Medicinal Chemistry: A Biochemical Approach
"The text is very readable and each chapter has a bibliography for further reading.  The book will be very useful for those wishing to understand the mechanisms of drug action and how to design new drugs." --International Journal of Biochemistry"Despite the intense interest in medicinal chemistry, there have been surprisingly few useful texts available . . . Almost all have been organized and oriented along the same lines, namely a discussion of drugs by pharmacological class.  This effort by Thomas Nogrady represents a major and refreshing departure from this format by emphasizing the biochemical basis of drug action . . . The book is a welcome and refreshing approach to the presentation of medicinal chemistry and should prove valuable." --Journal of Pharmaceutical Sciences (on the first edition)"Useful as an introductory book or a quick reference for medicinal chemists." --Journal of the American Chemists Society"The approach to medicinal chemistry presented in this book fills a void found in most medicinal chemistry textbooks. Its contents is very informative and this textbook should be utilized as a primary reference for undergraduate medicinal chemistry courses.  Because of its excellent organization and the up-to-date content, this textbook could serve as a textbook for graduate courses in introductory medicinal chemistry as well as for one which focuses on neurotransmitters, hormones and nonmessenger targets for drug action.  This book would be a valuable addition to any library that supports programs in medicinal chemistry or the other pharmaceutical sciences." --American Journal of Pharmaceutical Education"Includes a very comprehensive discussion of chemical and physical properties of drugs, and the general principles involved in their design.  It also has a nice discussion on the biochemical basis of their action, including alot of relevant background information on the systems involved--for example, nice sections on the biochemistry of hormone/receptor function, the biochemistry of neurotransmitters, and so on.  Another useful feature is a list of drugs at the end of the book. . . .good for medically minded biochemists and scientifically minded medical students." --New Scientist"The text is very readable and each chapter has a bibliography for further reading.  The book will be very useful for those wishing to understand the mechanism of drug action and how to design new drugs." --Gen. Pharmac."The text is very readable and each chapter has  a bibliography for further reading. The book will be very useful for those wishing to understand the mechanisms of drug action and how to design new drugs." --Comparative Biochemistry and Physiology"A concise review of the topic that is enhanced by several well chosen examples and numerous diagrams.. . . the author has highlighted the major findings in each area in a succinct, readable style, and has provided the reader with key references to recent reviews at the end of each section." --Drug Intelligence and Clinical Pharmacy--This text refers to an out of print or unavailable edition of this title.