Building an Elder God
You and your cultist friends have researched the hidden secrets of the universe and dark mysteries of the Great Old Ones to grow a tentacled horror from beyond the evils of space and time. Problem is, some of your research buddies are now growing their own monstrosities. No way do they get to steal your glory. You must ensure your beast is complete first which is why you brought your trusty shotgun. And if your precious, slimy baby is injured you brought your travel copy of the Necronomicon as a little healing insurance. Do whatever it takes for whoever has the first complete beast wins everything. Build a Cthulhu-esque tentacled monstrosity to completion before the other players, using damage cards to blast your opponents' creatures to slow down their progress so that you can win. Assuming no aversion to a little (goofy) implied violence and the sight of ichor, this is appropriate for friends and families.