The Compatibility Gene: How Our Bodies Fight Disease, Attract Others, and Define Our Selves
"Dr. Davis's readable and informative book takes the reader into unexpectedly interesting corners of both the immune system and the lives of immunologists. It is packed with an insider's knowledge - not just of the field, but of where its bodies are buried." -New York Times"...[A]n elegantly written, unexpectedly gripping account of how scientists painstakingly unravelled the way in which a small group of genes ... crucially influence, and unexpectedly interconnect, various aspects of our lives... Lab work has rarely been made to seem more interesting or heroic." --Bill Bryson, Guardian Books of the Year 2013"Davis ranges energetically through the research. Cultural references and anecdotes abound." --Nature"a fascinating, expertly told story" --The New Statesman"Davis provides a well-written and easy-to-read account of the sometimes complicated biology behind the crucial genes that affect our lives so profoundly" --New Scientist"Davis weaves a warm biographical thread through his tale of scientific discovery, revealing the drive and passion of those in the vanguard of research ... unusual results, astonishing implications and ethical dilemmas." -The Times of London"Davis makes the twists and turns all count." --The Guardian"Wonderful pen-portraits of the many scientists involved in this fast-moving field...5 out of 5 stars." --BBC Science Magazine FOCUS"Davis describes his task simply: '[T]his is the story of a few human genes and how we discovered what these genes do.' However, his book is far more complex and rich than such an explanation might lead us to expect." -Publishers Weekly"There aren't many stories of scientific endeavour that have never been told. This is one of them. Ostensibly about a set of genes that we all have and need, this book is really about the men and women who discovered them and worked out what they do. It's about brilliant insights and lucky guesses; the glory of being proved right and the paralysing fear of getting it wrong; the passion for cures and the lust for Nobels. It's a search for the essence of scientific greatness by a scientist who is headed that way himself.''-- Armand Marie Leroi, Professor of Evolutionary Developmental Biology, Imperial College London, author ofMutants"Who am I? What makes me different from everyone else? Daniel Davis recounts the remarkable science that has answered one version of these questions. He makes immunology as fascinating to popular science readers as cosmology, consciousness, and evolution."-- Steven Pinker, Johnstone Professor of Psychology, Harvard University, author ofHow the Mind WorksandThe Better Angels of Our Nature"What make us truly unique? Our personalities? Maybe, but more fundamental to the identity of each and every one of us is our spectrum of histocompatibility genes. Writing in a way that everyone can follow, Dan Davis tells this intriguing story. ''-- Peter C. Doherty, Professor of Biomedical Research at St Jude Children's Research Hospital, Memphis, USA, and at the University Of Melbourne Medical School, Australia, Winner of the Nobel Prize in Medicine for work on the immune system"In a rollicking romp through immunology's first century, Dan Davis expounds on the extraordinary genes that determine compatibility of donor organs with recipient patients in clinical transplantation.  By personalizing human immune systems, the compatibility genes have enabled individuals and populations to resist extinction by epidemic infections. If that were not enough, they also influence our brains, mate selection, and reproductive success.  Boasting a particularly rare set of compatibility genes, Davis has a raw talent for evoking the thrill and thrall of scientific research."-- Peter Parham, Professor of Structural Biology & Microbiology and Immunology, Stanford University, author ofThe Immune System"...[A]n elegantly written, unexpectedly gripping account of how scientists painstakingly unravelled the way in which a small group of genes ... crucially influence, and unexpectedly interconnect, various aspects of our lives... Lab work has rarely been made to seem more interesting or heroic." --Bill Bryson, Guardian Books of the Year 2013"The Compatibility Gene by Daniel M Davis is an elegantly written, unexpectedly gripping account of how scientists painstakingly unravelled the way in which a small group of genes (known as MHC genes) crucially influence, and unexpectedly interconnect, various aspects of our lives, from how well we fight off infection to how skilfully we find a mate. Lab work has rarely been made to seem more interesting or heroic." - Bill Bryson, The Guardian, Writers and critics on the best books of 2013"...the book presents a window into a prolific period of novel insights, early hypotheses that have since been rejected and groundbreaking discoveries." --Nature Medicine