Essentials of Chemical Biology: Structure and Dynamics of Biological Macromolecules
?Essentials in Chemical Biologyis a valuable resource not only for chemistry students who are venturing into and interested in biological systems, but also biochemistry and biology students who want a fundamental understanding of the physical and chemical basis of biology and the techniques used in its study.? (Chemistry World, August 2009)"The succinct and lucid presentation style ofEssentials Of Chemical Biologywill likely make it a popular resource for undergraduate and graduate students interested in the structure and interaction of biologically relevant macromolecules." (Journal of Chemical Biology, February 2009)"This excellent work fills the need for an upper-level graduate course resource that examines the latest biochemical, biophysical, and molecular biological methods for analyzing the structures and physical properties of biomolecules. Miller (Imperial College London, UK) and Tanner (Univ. of Hong Kong) cover traditional subjects such as binding interactions and catalysis. They also describe biophysical theories and current methods for protein structure determinations such as circular dichroism, X-ray crystallography, neutron diffraction, NMR, EPR, fluorescence, mass spectrometry, and electron and atomic force microscopy. For example, the chapter on solution NMR provides simplified yet high-quality explanations of the key principles of NMR. The well-developed introduction helps students to better follow the more complex information concerning the principles of multidimensional NMR. In addition, the latter part of the chapter offers current applications using a variety of multidimensional NMR spectroscopy experiments in the analysis of proteins, nucleic acid, carbohydrate, and lipid structures. This reviewer showedEssentials of Chemical Biologyto several of his senior graduate students, and they unanimously gave the book rave reviews. The work could be improved by better referencing the resource materials within the text and by providing student exercises at the end of each chapter."(J. M. Tomich, Kansas State University,Choice, February 2009)