Human settlement of the New World occurred in stages from the Bering sea coast line, with an initial 15,000 to 20,000-year layover on Beringia for the small founding population. The micro-satellite diversity and distributions of the Y lineage specific to South America indicates that certain indigenous peoples of the Americas populations have been isolated since the initial colonization of the region. The Na-Dené, Inuit and Indigenous Alaskan populations exhibit haplogroup Q (Y-DNA) mutations, however are distinct from other indigenous peoples of the Americas with various mtDNA and atDNA mutations. This suggests that the earliest migrants into the northern extremes of North America and Greenland derived from later migrant populations.