jkeisling/hacker-news-corpus-2007-2022 huggingface dataset:
Norton Medical and Scientific Research & Biotechnology
http://norton-scientificmedical.com/resources/
Norton Medical and Scientific Research & Biotechnology - FDA approves kidney cancer drug from Pfizer<p>BY ADMIN, 4 DAYS AGO
The medicine made by Pfizer against advanced kidney cancer was recently approved by Norton Medical and Scientific Research & Biotechnology regulators for commercial use despite a warning of possible side effects.
On Friday, the Food and Drug Administration (FDA) stated that the drug (with the generic name of axitinib) is effective in curing patients who do not show response to other drugs against kidney cancer.
The advance stage of kidney cancer usually begins in the lining of the kidney's tubes. Inlyta does its work by blocking specific receptors that are involved in the growth of tumor.
According to FDA, Inlyta is already the seventh drug it approved to cure advanced cancer of the kidney since 2005.
American Cancer Society said that more than 60,000 Americans are diagnosed with kidney cancer last year and 1 out of 5 is expected to die from them.
The FDA approval has come as a welcome opportunity for Pfizer since they have lost revenue from their cholesterol drug, Lipitor, after generic counterparts started to come out last year.
However, Inlyta will still face tough competition from the 6 other drugs for kidney cancer that have their respective market shares already.
An advisory committee of FDA endorsed the oral drug last month and announced that it is as effective and as safe as the kidney cancer medication from Bayer AG, Nexavar.
Generally, in clinical trials made by Norton Medical and Scientific Research & Biotechnology, Inlyta slowed the growth of cancer by 2 months versus Nexavar for patients who have already been cured for renal cell carcinoma.
However, the results differed based on what certain medicines patients have taken prior. For people who took first the Sutent (also from Pfizer), Inlyta slowed the spread of disease only by one and a half months, compared to the more than 5 months for patients treated with cytokines beforehand.
Most of the advisers of FDA stated that the drug does not have a huge advantage over others. However, the fact that it has different side effects than the other medicine in the market could be an important deciding factor for patients.
Several of the most common side effects of using Inlyta include high blood pressure, weight loss, vomiting, loss of voice and diarrhea. Some patients also reported bleeding problems that can possibly lead to fatality in extreme cases.
FDA issued a warning to patients with high blood pressure, intestinal bleeding, or untreated brain tumors in their intake of Inlyta.
Meanwhile, Pfizer is conducting further tests of Inlyta for liver cancer treatment.
The upcoming Kickstarter gadget that will make you shoot your iPad
http://www.snipedarts.com/
World's first app-integrated darts!
Most Re-tweeted Picture. 
https://twitter.com/TheEllenShow/status/440322224407314432/photo/1
2126189 so far!
Judge approves use of 'truth serum' in Colorado shooting case
http://www.guardian.co.uk/world/2013/mar/12/judge-approves-truth-serum-james-holmes
Not obviously HN-relevant from the headline, but an interesting and challenging intersection between law and the limits of neurological science.
MacKenzie Bezos reviews the new book on Amazon - The Everything Store
http://www.amazon.com/review/R2I0T26SV0ELPP
From the review: "The result is a lopsided and misleading portrait of the people and culture at Amazon."
Astronaut in space successfully controls robot rover on Earth
http://robohub.org/astronaut-on-international-space-station-successfully-controls-k10-rover-on-earth-supporting-use-of-telerobotics-in-future-deep-space-missions
On June 17, 2013, Astronaut Chris Cassidy successfully drove a K10 rover on earth, via remote connection from the Surface Telerobotics Workbench on the International Space Station, showing that robots deployed to explore Mars or the far side of the moon could be remotely controlled by astronauts in space during future deep-space missions. Telerobotics, which involves human operators remotely controlling robotic arms, rovers and other devices in space, is one means of reducing risk in dull, dangerous or dirty tasks as humans explore space. Dr. Terry Fong of the NASA Ames Intelligent Robotics Group describes how NASA’s telerobotics initiatives help mitigate risk in space missions.
Ask HN: /Onlinecasino showing up in my Google Analytics reports since today
Just checked my Google Analytics for a blog I run with AdSense on it.

Today there are a unusual high number of visits landing on a page with page path /onlinecasino in GA that doesn't exist on my website.

Traffic is coming from all over the world, but all of it is from Android and is new and not doing anything (100% bouncerate).

I'm worried this might have impact on my AdSense account as I don't want my site to be associated with online gambling.

Anybody experience with the same? Is there any danger to this? Is there anything I should do?
Force Facebook sharing by scaling like buttons
http://anton.trollback.se/blog/force-sharing-by-scaling-like-buttons/
I feel like I should tell people about this. Or maybe not..
Joinwire video
http://joinwire.com
Pretty funny. I wonder what problem they are trying to solve.
In Defense of Big (37 Signals on Six Apart -- 5 years ago)
http://37signals.com/svn/archives2/menas_counterpoint_corner_in_defense_of_big.php
Key quote: "I wouldn’t say a lot of employees and owing a lot of money to investors is any guarantee of longevity"
Show HN: Teach your kids numbers
http://incremental.ie/apps/mumbers
I've been working on this app at weekends for the last few months.

It is built using Appcelerator Titanium and I created a simple drag and drop animation framework as there was no native support.
Amazon built Top 500 supercomputer in its own EC2 cloud service
http://www.networkworld.com/news/2011/041111-amazon-cloud-supercomputer.html
Without much fanfare, Amazon officials last year built a supercomputer on the EC2 cloud service that placed 231st on the most recent Top 500 list of the world's fastest supercomputers. The 7,000-core cluster, de-provisioned soon after running the Linpack test, used Linux, Intel Xeon X5570 processors and a 10 Gigabit Ethernet interconnect. Amazon's James Hamilton said the Top 500 run proves that a cloud service can be used to build "One of the fastest supercomputers in the world for $1.60/node hour."
VX e-zine valhalla#3 released
http://spth.virii.lu/
virus-writing magazine valhalla#3 has been released - with new technology such as metamorphism in Javascript, GPGPU and AES-NI instructions for activation, own debuggers and inline-JScript to infect W32 files, JAR infector, True RNGs, virtual code, CFF scripts, ...

Interviews with Eric Filiol, Mark Stamp, VirusBuster
Importance of bibliography in academic writing
http://academicwriting4u.weebly.com/1/post/2012/02/what-is-the-importance-of-bibliography-in-academic-writing.html
Here you find all about importance of bibliography in academic writing
Puppet Custom Types. The easy way
http://hajee.github.io/2014/01/26/puppet-custom-types-the-easy-way/
Having difficulty writing a Puppet Custom Type? Find it hard to know all there is to known about Puppet internals. Check out this blog post. It introduces A library to make writing Puppet Custom Types easy. It helps you focus on the resource, not on the framework.
Show HN: My friend Vinnie has Leukemia, lets help him
http://www.gofundme.com/vinnies
Vinnie is an old friend of mine and a very happy + hardworking guy. I just finished visiting in the hospital, he's roughly half way through his first chemotherapy treatment and BCBS of IL is already giving him the run around about what they will and won't pay for. As a fellow survivor I remember my parents fighting with insurance companies tooth and nail to get them to cover their obligations.
A slightly, conservative, review of Hardy Heron
http://www.shelleytherepublican.com/the-definitive-review-of-ubuntu-linux-804-hardy-heron
The site has some very amusing sections, like their Linux section
http://www.shelleytherepublican.com/category/education/technical/linux

The other sections are mostly offensive. Please don't pay attention to them.

But what I want to know as someone who is not from the US is: are the people joking? or are they actually for real?
DIY Start Your Civilization Kit
http://opensourceecology.org/
The Global Village Construction Set (GVCS) is a modular, DIY, low-cost, high-performance platform that allows for the easy fabrication of the 50 different Industrial Machines that it takes to build a small, sustainable civilization with modern comforts.
10 Startup Ideas That Never Work
http://www.businessinsider.com/startup-ideas-2011-4
Most of these aren't surprising, but serves as a nice reinforcement with some good examples.
Toronto Lisp User's Group Meet tonight
http://www.lisptoronto.org/
Next meeting: July 7th, 2009 at 6pm at LinuxCaffe
Hello everyone! Our next meeting is coming up soon.

Toronto Lisp Users Group, July Meeting:
Tuesday July 7th, 6pm, at the Linux Caffe

Directions: walk south of Bloor from Christie Station, until you hit Harbord Street.

We're looking for volunteers for talks, discussion, and tutorials. We'd love to hear about your current projects, proposals for projects, libraries you like, tutorials or related LISPy languages, issues relevant to Lisp, etc.

As a special bonus for those who show up tomorrow: VJ has finally received his copy of "Programming Clojure", by Stuart Halloway! and will bring it in for anyone who wishes to thumb through it.
Divide and conquer: Play framework modules on openshift
http://playlatam.wordpress.com/2011/12/21/divide-and-conquer-play-framework-modules/
We all know the story. You start a new and shinny web application, and at the beginning it's all about adding features and fullfilling requirements. Sooner than later, you'll realize that you have to put some order into the mess that came out of a fast growing application.

Play! framework provides a simple and practical way to better organize your application and to encapsulate reusable behaviour: enter Play framework modules.

In this article we will learn how to make a simple module for adding Google Web Analytics suport to our web applications. At the same time, to test it on line, we will see how easy is to deploy our application to Openshift, Red Hat's cloud Platform as a Service (Paas) offering.

Check it out at: http://playlatam.wordpress.com/2011/12/21/divide-and-conquer-play-framework-modules/
Hyperlocal social app – need feedback
http://www.yo-app.com/
beta launched Yo!, would really be interested to have your views on whats not working right. Overall thoughts on Hyperlocal is also welcome.
Semantic and visual merge
http://codicesoftware.blogspot.com/2013/07/semanticmerge-goes-visual.html
Introducing a new way of displaying structural differences and merge conflicts with our semantic merge tool. Do you like it?
Deutsche Computerspiele?
I seldomly play games, but I really loved playing Braid, Word of Goo, and Machinerium.

I also really love learning German. I've been gradually stepping up my consumption of German media, from Sesamstraße and Kleiner Roter Traktor to Raumpatrouille.

Does anyone have any German language games to recommend? Maybe an RPG or something where text plays a role?

Other language-learning recommendations would be welcome, too.

Thanks!
Developer.Twitter.com goes to adscrimmage.Twitter.com
http://developer.twitter.com/
I have no idea why, but http://developer.twitter.com/ goes to https://adscrimmage.twitter.com/ -- try it out, it could be just me.
The School of Life (youtube autoplay)
https://www.youtube.com/user/schooloflifechannel
This is a nice collection of introductory videos to philosophical topics. I found the short bios of philosophers (for example Albert Camus [1]) especially entertaining.

Unfortunately the only good link to this collection is the Youtube channel and it has annoying autoplay.

[1] https://www.youtube.com/watch?v=jQOfbObFOCw
Ask HN: First Kinect startup?
With the recent news about Microsoft releasing Kinect's SDK (http://www.engadget.com/2011/04/13/microsoft-details-kinect-sdk-for-windows-pc-promises-robust-sk/)

When would you expect (if at all) to see a Kinect based startup?
Thursday Coffee featuring Facebook and OpenSocial
http://nabeel.typepad.com/brinking/2007/11/this-thursday--.html
These are fun, and worthwhile meetups.

I tend to find that talker show up at 8pm at bars. Those building stuff are willing to appear at 10am in a coffee house.
NYC Startup Founder Cycling Club
http://groupme.com/j/Afrpc1zlhZ4nQdT4
We just held our first ride this past weekend. If you're interested, join this GroupMe group!
Ask HN: node.js workshop
I have been doing node.js developing over the last 7 months or so and I am getting really good and productive at it. My company wants to organize a 1 day and a 2 day node.js workshop event for some other companies and have asked me to keep it. The workshops will be for around 30 devs. Can somebody suggest what topics should I include and how to schedule the calendar and what are the key points people usually want to hear/learn on these kind of events. ?
Driverless cars ready to hit our roads
http://www.newscientist.com/article/mg21328585.300-driverless-cars-ready-to-hit-our-roads.html
Sceptical about autonomous cars? Too late. They're already here – and they're smarter than ever
How are the laws in CA/US for working on a side project?
We are a couple of hackers working on an idea (full time). Still in its fancy, we have friends who maybe able to help part time, but dont want to quit their jobs yet. They work in big companies like Goog and Apple.

1. Is it legal for us to take their help? What are the laws on this?
2. The part time work is technically unrelated. They work on server code at work, and this is for a mobile app. But i understand it is hard to draw line on saying things are unrelated, after all it is SW.
3. Has anyone done this before?
4. Is it just a bad idea?
Show HN: HNsearch, a ruby gem for searching HN via command-line
https://rubygems.org/gems/HNsearch
I was learning to write RubyGems and this is what I came up with. I know that it doesn't follow the usual convention of lowercase naming but this is what I started with and then I ended up deploying it.

The gem doesn't do a lot other than query the HNsearch.com API and then just pretty prints the results. I am working on making it better and will be introducing some more commands.

I would like to get some review on my code quality and also how can I make this gem better.

I even wrote a small post on the same - http://aniketpant.com/2013/05/hnsearch-my-first-gem/
theNewAesthetic.js (Artware Javascript Library)
http://nickbriz.com/thenewaesthetic/
From the homepage:
"""
theNewAesthetic.js is an executable-essay / open-source javascript artware-library for quick [re]production of 'New Aesthetic' compositions and related new-media art tropes. theNewAesthetic.js is also the latest project in an ongoing series of New-Media Art One-Liners
"""
AWARE - Android framework for instrumenting mobile context information
http://www.awareframework.com/home/
"Android framework dedicated to instrument, infer, log and share mobile context information, for application developers, researchers and mobile phone users. The framework is scalable, where addons take form as Context Plugins and Context Sensors. The framework is event-driven and power-efficient."
Norwegian Army using Oculus Rift to drive APC
http://translate.google.com/translate?sl=no&tl=en&js=y&prev=_t&hl=en&ie=UTF-8&u=http%3A%2F%2Fwww.tu.no%2Fit%2F2014%2F04%2F15%2Fse-haren-kjore-stridsvogn-med-oculus-rift&edit-text=
Article translated from Norwegian to English using Google translate.
How to solve common IE bugs
http://www.red-team-design.com/how-to-solve-common-ie-bugs
Sometimes, when working on some projects that require cross-browser compatibility, you need to know how to action when you encounter IE bugs.
Ask HN: What's the cheapest international periodic payment solution?
Very probably there are some fintech solutions I am not aware of. For that reason I'd like to have your professional opinion on the best way to pay a loan internationally and periodically! In this case it is from Europe (in specific the Netherlands) to the USA.

The receiving party in the USA is a party which accepts:

* manual credit card transactions initiated though cell phone calls, this is not periodic so and its a pain to call them every time
* checks, however, we don't have these in the Netherlands, especially not for periodic payments
* periodic payments through a local bank in the USA

So, the third option it is, we will pay periodically from a bank in the USA. But now we have to set up periodic payments to that bank as well.

What's the best way to set this up?

On http://www.mybanktracker.com/news/wire-transfer-fee-comparison-top-10-us-banks an incoming foreign wire transfer fee ranges from $15 to $30. On http://www.mybanktracker.com/news/2014/05/13/wire-transfer-fees-top-10-credit-unions-spring-2014/ I see that there are credit unions that have free incoming foreign wire transfer fees. Is that easy to setup and how are the exchange rates? Perhaps there are totally different financial services I'm not aware of. Periodicity is essential however!
Punchlines by QR Code
http://blog.makezine.com/archive/2011/08/qr-code-joke-punchlines.html
Finally a use for QR Codes
Bitcoind pyminer with pythonparallel support
https://github.com/daedalus/pyminer
I want to know what you think about it.
I know ASIC's are comming...
Show HN: A pure rust discord bot hosted on Cloudflare workers
https://github.com/mcdallas/rust-discord-bot
Hi HN,

I've made a discord bot template that you can clone and create your own bots.

It's a serverless bot hosted on cloudflare workers which looks like a great use case for this sort of thing.

Using workers you have almost zero (<5ms) cold start time for your functions. With a free account you get up to 100k requests per day and you can store/access state using KV or durable objects.

Workers only support Javascript and WASM in their runtime. This bot is writter in pure rust which compiles to WASM and deploys your worker with a simple CLI command.

I've made a couple of bots using this template, mainly for stitching together rest APIs and the response times are pretty great.

That's all, thanks!
Popular Podcasts for Developers
Some of my favourite podcasts:

Software Engineering Daily - https://softwareengineeringdaily.com
JS Party - https://changelog.com/jsparty
Darknet Diaries - https://darknetdiaries.com/
Changelog - https://changelog.com/podcast
Corecursive - https://corecursive.com/

Any others that people here recommend?
Why Your Product-Driven Team Sucks at Sales
http://blog.9slides.com/2014/01/24/top-10-reasons-why-you-suck-at-sales/
Unless everybody in your team is not collaborating with the aim of generating revenue in mind, you won’t have the opportunity to build what you know is possible. Watch this talk to learn more.
Show HN: GitHub code review assistant
http://userscripts.org/scripts/show/153049
Hi, I wrote a simple userscript to enrich the commit and pull request pages of GH. I find it useful to analyze big commits.

Tested on Firefox 17 / GreaseMonkey 1.5. It's basically a vanilla JS so should work as a bookmarklet also but I prefer this to fire automatically.

Looking forward to your comments. You can suggests enhancements / bugs on GH: https://github.com/jakub-g/greasemonkey-userscripts

Enjoy,
Jakub
BitTorrent’s Plan for 2013? Go Legit
http://bits.blogs.nytimes.com/2012/11/30/bittorrents-plan-for-2013-go-legit/?nl=todaysheadlines&emc=edit_th_20121201
BitTorrent’s Plan for 2013? Go Legit
Scientists can't find evidence for damages by Online Film Piracy 
http://papers.ssrn.com/sol3/papers.cfm?abstract_id=1986299
No damages to the film industry in the U.S. could be proven - outside of the U.S. 7%, mainly because of delayed film releases
Metaprogramming a full Virtual Machine
http://vermeille.fr
C++ is a wonderful language which allows genericity and performance with the technique of metaprogramming, almost discovered by mistake. We will see how to implement a virtual machine with such tools.
Ask HN: What e-mail client do you use?
I was about to http://www.indev.ca/MailTags.html. A really awesome (it seems to me for now) plugin for Apple Mail that enables tags. But before that I wondered if I haven't missed anything and will regret spending the money. I'd love to use something that I know will be there in 10-20 years rather than pretty and trendy software products like Sparrow... as they all have the same fate - either aqcuired or abandoned.
I saw this the other day in the app store - http://www.handle.com/
Looks great! But I doubt it will exist in 2 years.
Mailbox seems good but it's owned by Dropbox and that makes me slightly uncomfortable.
But I still want something that looks good... and I also love tags/labels which are supported unfortunately only by Gmail and MailTags for Apple Mail.
So I don't know if I can switch to something like Mutt.

So what does HN use?
Ask HN: Can anyone recommend a good Ruby/Rails bootcamp?
I've been looking at a lot of bootcamps and short intense training sessions with ROR, but there's a lot of options and I'm not sure exactly what to look for. Has anyone attended one in the past or have some insider knowledge?
Ask HN: People who hate talking on the phone, how do you deal with remote work?
I know quite a few people who hate being on the phone, from kids to adults. The reasons are many, but some people definitely feel more stressed during a telephonic interaction vs. an in-person one.

To those people on HN, I ask: How are you coping with remote work, especially if you started doing more remote work in 2020, and do you have any tips or tricks to share with others who might share your plight?
Show HN: I made a player to watch movies together over the internet
https://github.com/hammadfauz/syncPlay
A Nodejs-based app for playing local videos in-sync, in the browser. Dedicated to my fiance, for watching movies and tv-series with her. ;)
Discussion at Harvard regarding non-compete agreements
http://www.gototheboard.com/articles/June_19th:_Discussion_About_NonCompetes_at_Harvard_Law
For anyone interested, a round table discussion of non-compete agreements and their impact at Harvard.
What To Expect After Your First Meeting With A VC
http://getventure.typepad.com/markpeterdavis/2007/10/what-to-expect-.html
After you have had your first meeting, VCs may be slow to respond. There are a few potential reasons for this...
Ask HN: Review my startup: clubcompy.com
ClubCompy is a hosted programming environment designed to introduce children to computers and programming. We've built a language reminiscent of '80s BASIC and Logo in HTML 5 and JavaScript so that the only requirement for use is a modern web browser.

We believe that a quarterly newsletter with lessons and printed listings will appeal to our target audience. The site is free to use, but only subscribers get server-side storage.