jkeisling/hacker-news-corpus-2007-2022 huggingface dataset:
I have worked in the Biotech industry and worked with both the FDA and CDC.

The CDC and FDA have separate missions. The CDC tries to manage diseases once local authorities become overwhelmed. They maintain the Strategic National Stockpile. The SNS is a stockpile of different drugs, not enough for everyone, but enough to hopefully contain an outbreak. Our particular vaccine was FDA approved, and purchased for the SNS. The CDC also may purchase drugs that have not yet been FDA approved (depending on the political climate).

The FDA is the regulatory agency that polices, in this article's case, drugs. They monitor the clinical trials, and manufacturing process of the drugs (gmp-good manufacturing process). The FDA makes sure that drug companies do not exaggerate the efficacy of their products.

So it is not really that surprising that an agency that monitors and manages diseases would recommend drugs, while the agency that monitors and manages drugs would point to drug efficacy first.
Maybe a bunch of people emailed him after hearing the news?
You can definitely do this, but you need to be smart about it and assess how much time you realistically have. If you do have, 10-15hrs a week - this could be great. I won't comment if you actually will have this time - that's your call! But assuming you want to:

How I'd do it:
- If you don't have a great website with your work / skills - MAKE ONE NOW! Also, get some business cards - as cliche / outdated that is - it makes the old men think you're serious - along with good work on your site.

- Go on StartupDigest, Meetup, Craigslist, OHours, etc. and find the local networking events for web design, tech, startups and small business - then attend all of them that look promising.

- You won't have the time to drum up a ton of business on your own, but you can show your site to the people you meet who are already serving the same customers - here are the targets:

+ Other Freelance Web Designers / Programmers / etc.

+ Tech "connectors" - who shows up at all these meet ups and know everyone? - find them

+ Consultants / Business Service People - these people often provide ancillary services like translation, HR, etc., but they're always looking for more services they can provide their clients. They are often snakes, but when they get a client interested - it's still money. Just filter appropriately.

Impress the good people you meet & keep up-to-date - you'll get some pretty easy deal flow - programmers are in high demand everywhere & you can afford to be selective & charge market / premium pricing.

INAL and not sure on your background, but you should probably set up a simple S-Corp / LLC and have a simple contract - even steal another service providers - you want shit on paper to keep in clean & filter the shit clients.

Hope that helps.
I don't think such low level access will be allowed. Would be cool but it is a lot of work and means to change the scripting layer every time we change the internals. I'll start with something much higher level than that.
It talks about it in the FAQ they put out. Crowd sourced database and all. They are even talking about building a product based on the data with regards to traffic and directions.

http://www.apple.com/pr/library/2011/04/27location_qa.html
Chart drawing is useful (if only for visually exploring the data). I wouldn't be willing to be tied to your service, so you may want to integrate some standard library?

A chroot-like system would work fine, and also make it easy to export data.

This also needs a live demo. And have you already figured out how to make the Python interpreter persist across reboots?
The problem is exactly the one with VM: I believe that likely disk will suck but for a specific work load, that is, extremely biased working set + mostly reads. But this is exactly the use case of on disk DBs anyway, that are doing a lot work to work well in this use case, why should we also enter this business? There should be space for everybody, I'll be very happy if we'll do our work well, that is, the in memory data structure server :)

BUT I did not stop experimenting, we'll return on this, but in the form of diskstore and as on disk allocators using mmap() that is another thing I'm playing with.
With the iPhone(s) becoming the most used camera on flickr it's a shame this won't work for iPhone (at least 3gs)... "does not write serial information"
It's actually quite clear -- group housing doesn't inherently drive most people insane after months. Solitary confinement does.

http://www.newyorker.com/reporting/2009/03/30/090330fa_fact_...

Change it from less than 1 hour of contact per day to something like 4, and I doubt it would be harmful.
What fallacy?
"Labour used to be much cheaper." - with 10% unemployment in the US (that's higher if you use more accurate measures), I'm not quite sure why the reason for this would be a lack of available labor.
Welders might buy this - they already have auto-darkening helmets, they might be interested in something that darkened only part of the field of vision.

Of course you would have to be very careful on the design, since a failure would be very hazardous.
Political affiliation is only one of many ideological and demographic dividing lines that the Digg power users carved out.
Pagination is definitely better than manual scrolling, but I find iBooks' animation too visually fancy. The Kindle iPad app is better: it just slides the new page in.
I hope they'll add cool stuff from functional web (continuations, etc.) programming, like in Arc, Ocsigen, Seaside or Ur/Web.
That one is better, a close up, thanks from cloudy south eastern Canada!
You know what, I agree. But today after the release of ImpactJS I thought, f* it. Release! On my giant todo list, this is one, I assure you.
NaCl might be good for doing the transcoding on the client side before uploading - and would be especially helpful if the transcoding is a downsampling (i.e. reducing stream length), and if the client machine is beefy enough to do it without adversely affecting performance when pumping out bits at the rate of the upload connection.

However, it wouldn't be particularly useful for things like queuing uploads from a directory. The point of NaCl is running native machine code in a provably secure sandbox. It's about making possible web app features faster on the client side, rather than adding new capability, per se.
Fission is non-renewable. We might get 50 years of economical generation with current technology, maybe more with breeder reactors. Germany spent 3.6 billion euros on the SNR-300 reactor and never got useful output from it, nor America from the 8 billion dollar Clinch River reactor. Monju at least produced power, but only for four months before it blew up. At this stage, economical breeder reactors are an entirely hypothetical proposition. The next generation of reactors in development are only around 15% more efficient than the best extant facilities.

We cannot continue to act on the hope that some future generation will fix our energy problems with a hypothetical technology. It is energy policy of the dot-com bubble. There is an outside possibility that technology might save us, but it is just that, a possibility. There is no roadmap, no plan, merely some things that might work, maybe, some day. Without such a hypothetical breakthrough, there is simply no possibility of continuing our current rate of energy production.

I highly recommend Dr David MacKay's book "Energy Without the Hot Air". In it, he surveys the production possibilities of all the currently viable technologies, gives current consumption levels of British people, and leaves the reader to decide how to make one number match the other. It is impeccably researched and available to read for free online - http://www.inference.phy.cam.ac.uk/withouthotair/
I didn't mean the act of being the centre of your own universe, but him transitioning to being the centre of his own would have immediate detrimental effects if he decided to chase something like a bloodhound.

Like I said, he should find something to do in his free time that fulfils his transition. If you're dedicated, you'll soon be making money one way or another and can switch to that as your day job.

It's inadvisable to anyone who's self-supporting or supporting others to make a drastic change. There's no point trying to self-actualize if you're going to starve in the process, because you'll never get there.
My recommendation to use minimal semicolons is a very weak suggestion. I took great care to make that clear, and to point out a few cases where it makes perfect sense to use more semicolons than strictly necessary.

My recommendation against lying is much more forceful.
I’m not familiar with Android phones. I have never seen or heard of anyone intentionally rebooting or shutting down his or her iPhone or iPod touch, though.
I got a Pebble a few weeks ago. I use it for sleep tracking as well as daily wear, so charging at night isn't an option. I've gotten into the habit of charging it every morning while I shower and shave. Even when I'm extra-quick with my morning routine, I still find that the 15-20 minutes is enough to bring it back to 100%.

From everything I've read, lithium batteries actually do better when they're not discharged all the way—the only downside being that the device's battery gauge can lose calibration over time (hence the recommendation to do a deep discharge every 30-50 cycles or so).

This habit also will extend the useful life of the watch for me: Since I'm already in the habit of topping off daily, when the battery begins to lose capacity (down to 3 days from the initial 7, for instance), I won't even notice.
I do both FPGA and high performance ASIC design for a living - there is typically a pretty big gap between something designed well for an FPGA and something designed well for an ASIC. You’re probably making use of FPGA-specific hard IP (memories, PLLs, PHYs, etc.) that you’ll need to replace, and the logic will have been implemented in a way that’s tuned to the timing trade offs on an FPGA. Clicking “recompile” is only the case if your design has terrible performance in an FPGA and you want awful performance in an ASIC too.
Ain't that the truth! I guess where I'm trying to draw the parallel is that it's becoming somewhat of a "default" where people aren't critically thinking about whether it's right for them, they just see dollar signs. Maybe that is what strikes me as a little bubble-ish. (I'm young though and have not been through a downturn in my career, so what do I know)
> That's because some people should think harder about their comparisons before they verbalize them. The quoted comment poo-pooed an existing product that you could buy with a mere trip to one's local Apple retailer.

cmdrtaco was also criticizing the product as it existed at the time, not the product it would evolve into which, in retrospect, made his criticism seem ridiculous. He was criticizing the first revision which had poor connectivity (firewire only) and little storage (5GB on launch, 10GB later.) The fourth revision, the one that actually became a run-away success, had 20-60GB of storage and was the first to have full USB support.

https://en.wikipedia.org/wiki/IPod#/media/File:Ipod_sales_pe...
As long as the officers of ShapeShift or its shareholders are within reach of the U.S. government, those rules are physically enforceable.
Comments merged into https://news.ycombinator.com/item?id=25661474.
Coup-o-meter is right on the line between "preparing for a coup" and "attempted coup" https://isthisacoup.com/
Listen to the tape of the Trump call to Georgia, or better yet this Georgia election official's point-by-point takedown of Trump's claims: https://www.nytimes.com/2021/01/04/us/politics/trump-georgia...

There simply is no reality based reason to believe that the election was stolen, certainly not in any consistently logical belief system (e.g. the 2016 Electoral College results were almost exactly the same in the opposite direction).
He is submitting more because they keep getting flagged.

There is a coup going on right now. How do you not understand what is happening?
Can you please share your thesis for ShapeShift from an equity upside standpoint?
Not sure, there was smoke near the entrance area in one video I seen. So, possibly, but no idea.
This is the answer, I don't have the source in front of me but I remember reading some surveys about American trust in institutions circa 2015 and people who identified as Republican trusted "Media" at a rate of 8%. I can't imagine that number particularly improved since then.
Chapeau, good move. Your honesty is impressive.

IMO paying money and thus enabling humane businesses to thrive is key.
Hi, Anders here. I'm currently working on a BI SaaS that might be a good replacement for Chartio: https://www.rationalbi.com

It's a modern take on BI/Analytics, and has all the typical business intelligence functionality: dashboards, scheduled reporting, enterprise security and SAML as well as notebook analytics (like Observable/Jupyter).

You can just drop in data files of any kind, syndicate data from your cloud drives, connect to remote databases, upload via the API, and it has 80k+ open datasets available for analysis and benchmarking.

It also has a full SQL database running in the browser, so if you build dynamic notebooks/dashboards with business logic, you can do really fast SQL without any network latencies.

Disclaimer: Founder of Rational BI.
I can't stand graffiti, please don't enable this kind of behavior.
That's just a support for CPU rendering. How are going to render without GPU acceleration? It might take hours to finish.
IMO animations are a hurdle more than an aid. macOS has so many long animations that it takes everything longer. 300ms might not be long, but it adds up. For first few times, animations are cool. But the novelty wears off when you need to do the same action 80th time.

Animations regardless of the domain should be used extremely sparingly. It’s appalling that JS frameworks such as Svelte has this built in. It’s only going to encourage more animations.

I can only imaging how much faster macOS would feel if for example exposè had no animation. Forget about better processors and GPU, the easiest way to make the entire OS faster by 500% would be to turn off all animations. Unfortunately, Apple doesn’t allow us. Even accessibility settings for “reduce motion” just uses fade-in/out animation instead. I really don’t buy the arguments for animation “it gives context to where things come from and where they pop out”. I find that disputable, sure good for initial familiarity but painful the second time.
Yes, a lot of this kind of "everyone is replaceable" 4D chess mentality of management leads to a fat middle.

I've seen this both at large, stodgy organizations that have frequent layoffs and at smaller organizations with Frank Underwood CTOs.

Bottom performers get managed out on the firms schedule, but top performers find their way out on their own schedule. This can lead to great chaos.. people getting un-fired, throwing money at the key man risks you accidentally created, and over-correcting with too-fast over-hiring which then leads to inevitable future firings.
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My name is Andrei Pervychine, I'm a Full Stack Senior developer with a Master's degree, and a lot of experience with Mobile Technologies. I'm a generalist that can get you from a PSD file to a website/mobile app built using the latest tech, clean code capable of scaling to a million users and take care of the hosting (Apache setup, AWS).
I can only comment on the study in front of me, and not the use cases that 'might have been'. In this case, they tested in a healthcare setting as there is a presumed higher risk of catching covid amongst participants. Would the same false positive rate be true in the community, where transmission is much lower? We don't know because that wasn't the experiment.
The study authors claim that this is useful in the healthcare setting- I'm saying that it's useless because there are better tools in the arsenal (lateral flow tests), and watches are an infection risk.
I can't disagree. With one exception, that being Raymond Hettinger, it's to the point of cringiness when someone says "pythonic". The last 2 years of my last job was 99% python, and the smug, "we love what we did and nothing else" attitude I think you've exactly captured.

I know this is not universal, but I've seen it online a lot, and lived it for far too long.
FileMaker's quiet, sustained success over the years makes you wonder why Microsoft didn't spin off FoxPro in the same way that Apple spun off Claris. Perhaps they were worried it would be too competitive with their own core products?
Which one was it? The common one is Universal Certification and Surveillance Services Trade Co. [0]

What I’ve heard, is that almost all the European labs had crazy backlogs for certification of PPE and the Turkish one was the only one with capacity.

[0] www.universalcert.com
However you might describe the present state of firefox,
"success" is unlikely to be one of the adjectives.
The term "window snapping" must have some precise definition that I'm unaware of, because the Mac does have behaviors that I would call "window snapping":

- On the Mac, when you drag a window to a side or bottom edge of the screen, it will "catch" on the edge, making it easy to avoid dragging it partially off of the screen. In Windows, when I want to move a window to the edge of a screen, I have to be very slow and careful to get it just up to the edge without going over.

- Likewise on the Mac, windows will "catch" on the edges of other windows, making it easy to put windows up against each other with no overlap or intervening space

- If you click and hold the Maximize button, you get a menu that gives you the option to tile the window to the left or right half of the screen

So, what exactly is this "window snapping" feature that Windows has that the Mac doesn't? I'm genuinely clueless and curious.
Funnily enough these "small" things are probably the biggest barrier for switching. I'm a long-time mac user and I asked for a Surface laptop at my new job to give me some variation. Luckily I was able to switch to a Macbook Pro after a year or so, not because of the mouse but because of Windows' awful font rendering.

I know, I know, some people prefer the Windows way of rendering, but I just get sad :) Great system otherwise, especially with WSL!
Also set up a non-Gmail email and redirect your account recovery across all services there, because if Google suddenly bans you from Gmail and it's your only recovery email for a service, you may get locked out of it permanently.
I only found this:
https://man7.org/tlpi/

Is there any free or low-cost version?
Love this. If only Hacker News and Reddit would implement it.
> Department of Labor can crack down on the company for not paying the "prevailing" wage.

That is technically true, but effectively impossible. The DoL simply does not pursue H1B abuses. They do not have the political will nor the budget to even look for them.

There is literally zero budget allocated to "prevailing wage" enforcement. That is a deliberate oversight by congress and has been that way for the 20+ years I've been observing the H1B process. To the best of my knowledge the DoL has only twice ever initiated action for H1B prevailing wage violations and in both cases it was the result of a disgruntled employee tipping them off to a series of violations that were so egregious that the political fallout of ignoring them would have gotten senior bureaucrats fired.

You might also want to read up on how classifications are gamed in order to work around even the very minor risk of prevailing wage violations.

http://www.cringely.com/2012/10/23/what-americans-dont-know-...
Some time ago I read something that seemed a much stronger case against the Year of the Desktop Linux - lack of binary compatibility. It is hard to develop commercial software for Linux, when it means building your software for every distribution and supporting all of them. Anyone buying a piece of software would probably have to stop upgrading their system if they want to keep using the software. Different desktops add to this pain, but not as much.

Of course, Linux is not about buying software, so I guess not many people care. But the availability of a certain, professional piece of software (aka "killer app"?) is often what eliminates Linux as a choice for many people, in my experience. (That is, now that there are good graphics drivers available and you can watch bloody YouTube.) Ultimately, in a very ironic twist, this makes Linux most suitable for people who do not know anything about computers. I install them Ubuntu, they don't touch anything except updates, and everybody's happy.
I disclosed on my employment contract for IP reasons. But I didn't go into specifics.
I don't want what Bradley Mannig has done to be compared to what Edward Snowden has been doing.
It's a dramatized example intended only to illustrate the point.
Oh I agree that he mentions it in his article, but everything he says is good about his library is already done (better, I might add) by Web API.
Why is there no Reddit integration?

Pitting /r/atheism and /r/Christianity together (just an example), might be quite effective. In fact I believe it already happened in the past though I can't remember the specific instance right now.
When military technology enters the mainstream, and becomes the basis of technology in widespread use by the public, it goes without saying that the original military specifications are the initial "standards" present for that technology.

This isn't the same as the government attempting to mandate standards for public use, especially with the intent to alter the way people are already using technology.

In your list, only GPS represents a technology originally used by the military, whose initial military specification still mostly describes its current function. Everything else, and especially the Internet - which grew out of a DARPA project, but certainly isn't one any longer - is either a vague category (electrical/safety standards), areas in which standards have not originated from government mandates (telephony, the Internet, time zones), or areas in which government attempts to shift standards have been demonstrable failures (metric usage in the US).
How is losing $450 a win for the seller? You mean it was a requirement to get your business, to throw in $450 of extras? I hope it was a very real coffee machine. Plumbed variety? :)
Sounds like a poor idea to me. Eyeballs are already cheap and plentiful, especially if you are not particular about what kind of eyeballs you can get.

Today, I can get narrowly specified demographic eyeballs from Facebook, of users who have are documented to have interests that make them good prospects for my business, with a link to my site, quite cheaply.
I'm not say the way he did the martial arts thing is the way to go. Personally, I wouldn't be able to pull it off because I don't think I would be able to face the other players and not feel bad about what I was doing.

But, by his definition, and by those set up by that martial arts sport, he did win, and he got the title/paper to prove it. What can you say, some people like titles/papers more than the actual process :)