Claim: The Crazies is real.

The Crazies is a 2010 American science fiction horror film directed by Breck Eisner , with a screenplay by Scott Kosar and Ray Wright . The film is a remake of the 1973 film of the same name by George A. Romero , who is an executive producer of the remake .   The Crazies stars Timothy Olyphant and Radha Mitchell . The film takes place in the fictional town of Ogden Marsh , Pierce County , Iowa , `` friendliest place on Earth , '' whose town water supply is accidentally infected with the `` Trixie '' virus . After an incubation period of 48 hours , this virus gradually transforms the mental state of the infected into that of cold , calculating , depraved , bloodthirsty killers , who then prey on family and neighbors alike . The film was released on February 26 , 2010 to positive reviews from critics , and was a modest box office success .