Claim: 50 First Dates is a romantic comedy film starring Drew Barrymore.

50 First Dates is a 2004 American romantic comedy film directed by Peter Segal and written by George Wing . The film stars Adam Sandler as a lothario veterinarian and Drew Barrymore as an amnesiac , along with Rob Schneider , Sean Astin , Lusia Strus , Blake Clark , and Dan Aykroyd . Most of the film was shot on location in Oahu , Hawaii on the Windward side and the North Shore . Sandler and Barrymore won an MTV award . The fictitious memory impairment suffered by Barrymore 's character , Goldfield 's Syndrome , is similar to short term memory loss and anterograde amnesia . The 2014 Malayalam film Ormayundo Ee Mukham is inspired by 50 First Dates .