jimnoneill/paper-to-field-training huggingface dataset:
Open and structured assessment in addressing hospitalized cancer-related problems: The perception of patients and nurses in Indonesia

Purpose Although the concept of ‘cancer-related problems’ is complex, few studies compare nurses’ and caregivers’ perspectives on cancer-related problems, particularly in eastern cultures. The study aimed to identify the perceptions of patients and nurses concerning to what extent the problems of patients with cancer were assessed and addressed during hospitalization in Indonesia.Method A descriptive correlational study with cross-sectional comparisons was conducted in three major cities in Indonesia. With a convenience sample of 119 patients (response rate = 79.3%) with cancer and 147 nurses (response rate = 71%). The domains of validated Problems and Needs of Palliative Care – short version were used to measure the perceptions of the patients and nurses regarding the assessing and addressing of patients’ problems.Results The patients stated that their physical and psychological problems were very often assessed (>84%) and addressed (>90%). Patients who reported difficulties spontaneously had a lower prevalence of problems than patients who reported problems to a professional, except for the psychological subscale (P-value 0.05). The open assessment reported that the problems exhibited lower frequency than structure assessment, while nurses addressed all sub-scale problems (P-value < 0.005). Patients’ educational status, age, gender, and time of diagnosis had positive correlations with their perceptions of cancer-related problems, which they voluntarily stated.Conclusion These findings indicate essential similarities and incongruities between patients with cancer and nurses perceive cancer-related problems. The results highlight the complex technical directions of cancer nursing care in Indonesia.

Topic: Palliative Care and End-of-Life Issues
Subfield: Public Health, Environmental and Occupational Health
Field: Medicine
Domain: Health Sciences
Effect of fruit shape on core rot caused by Phomopsis sp. in Japanese pear cv. ‘Kosui’

The effect of fruit shape on the incidence of core rot caused by Phomopsis sp. in Japanese pear cv. ‘ Kosui’ was investigated in 3 field experiments during 1999-2000. One finding was that fruit where the diameter of the calyx tube at harvest was bigger than 1 mm had an incidence of core rot twice (41.3%) as high as fruit (22.1%) with a tube diameter smaller than 1 mm. Moreover the rate in fruit with a calyx hole bigger than 1mm when measured 52 days after full bloom stage was remarkably higher for flattened fruit compared to those with an oval shape. I estimated that it would be possible to greatly reduce the incidence of core rot if flattened fruit were selectively removed within 2 months after full bloom stage.

Topic: Plant Pathogens and Fungal Diseases
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Kinetic Model of Batch Lipase-Catalyzed Esterification Process with Function of Temperature and Water Content

Lipase-catalyzed esterification process has emerged as an effective technique for the esters formation. The interaction of temperature and water content with catalyst kinetic activity creates a variation in reaction rate that affect the productivity of esters production. In this work, the effect of temperature and water content variation on the kinetics of lipase-catalyzed reaction is analyzed. A mathematical model of the lipase-catalyzed esterification process that considers the effects of temperature and water content on esters dynamics is developed. The developed model is then solved numerically to obtain a better understanding of the ester dynamics at various time scales. As a result, the developed model showed strong predictive capability for the chronological production of esters.

Topic: Enzyme Catalysis and Immobilization
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
<i>S</i>-Methyl-<scp>l</scp>-cysteine targeting MsrA attenuates Ang II-induced oxidative stress and atrial remodeling <i>via</i> the p38 MAPK signaling pathway

SMLC protects against atrial remodeling of AF by inhibiting oxidative stress through the mediation of the MsrA/p38 MAPK signaling pathway

Topic: Receptor Mechanisms and Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Validity of two-dimensional ultrasound for determining extreme foetal weights to term

The aim of this study was to assess the validity of ultrasound carried out within seven days prior to birth at term for the calculation of full term estimated foetal weight (EFW) in order to diagnose extreme foetal weight, performed using a single-center retrospective cohort study of 2500 pregnant women. Ultrasound calculations of EFW with a standard error of less than 10% showed an accuracy ratio of 75.1% for the total sample. This percentage was similar for appropriate for gestational age (78.6%) and normal foetal weights (77.5%) but decreased significantly (<i>p</i> < .01) in the case of extreme foetal weights. The simple error increased in both the high and low EFWs, taking on positive values for the low weights and negative values for the high weights. As for the percentage error values, there was a tendency for positive errors for low weights and negative errors for high weights; this led to a tendency to overestimate low foetal weights and underestimate high foetal weights.IMPACT STATEMENT<b>What is already known on this subject?</b> Two-dimensional ultrasound is currently the principal tool used in obstetrics to evaluate foetal growth, mainly through the calculation of EFW. Foetal weight represents an important prognostic factor in perinatal results, with a greater risk of adverse effects in cases of extreme foetal weights. In this sense, there are few studies that assess the validity of EFW calculations focussing on extreme foetal weights to term.<b>What do the results of this study add?</b> The ultrasound estimates of EFW with an error lower than 10% in the seven days prior to birth showed an accuracy ratio of 75.1% for the total sample. This percentage was similar to appropriate for gestational age weights (78.6%) and of normal weights (77.5%), but decreased significantly (<i>p</i> < .01) in the case of extreme foetal weights: small for gestational age (52.1%), large for gestational age (68.2%), microsomia (49.1%), and macrosomia (61%). Likewise, we found high specificity and low sensitivity for ultrasound diagnosis of extreme foetal weights.<b>What are the implications of these findings for clinical practice and/or future research?</b> The validity of ultrasound EFW is influenced by extreme foetal weights, with a tendency to overestimate low weights and underestimate high weights, which represents a clinically important finding.

Topic: Pregnancy and preeclampsia studies
Subfield: Obstetrics and Gynecology
Field: Medicine
Domain: Health Sciences
Animated Game “Let's Pray at Al-Aqsa Mosque (Asma)”: The Development of An Islamic Medium of Learning Related to Al-Aqsa Mosque and Islamicjerussalem (Baitul Maqdis) For Children

Animation is one of the educational methodologies through entertainment that is very close to the world of children. However, the number of animations with Islamic patterns is still less either on television or on youtube channels. Therefore, the educational method using animation should be highlighted to educate children because this group is more receptive to messages through this method. The issue of Al-Aqsa Mosque and Islamicjerussalem (Baitul Maqdis) received a warm response among adults and the Palestinian people remain the focus of the world, including Malaysia. Based on solidarity, Muslims continue to help the Palestinians defend the al-Aqsa Mosque and Islamicjerussalem (Baitul Maqdis). Even so, the importance of Al Aqsa Mosque as the third main mosque in Islam and also the importance of Islamicjerussalem (Baitul Maqdis) in the history of Islam are not exposed to children. Unlike the more well-known Masjidil Haram and Masjid Nabawi, there are even parents who take their children to perform Umrah or Hajj at a young age. Thus, an animated game android application called 'Let's pray at Al-Aqsa Mosque (ASMA) has been developed using ADDIE Model, to provide key and accurate information about Al-Aqsa Mosque and Baitul Maqdis to children, in addition to fostering a sense of love for the most third important mosque to Muslims. The ASMA animated game android application is developed using three languages; Malay, Arabic, and English for children with the 2-in-1 benefit that is education and entertainment. The ASMA application was tested for usability by selecting a group of primary school students as respondents. The results of the study show that the majority of respondents can understand the content of the ASMA application. They also believe that this animated game is challenging, and entertaining and can train patience in a person. The existence of ASMA's animated game application is expected to fill the loophole in the latest Islamic medium for learning and related to Al-Aqsa Mosque and Baitul Maqdis, for children.

Topic: Education and Islamic Studies
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Study on the Transmissible Torque of HSK-E50 Toolholder-Spindle Interface

This paper introduces a methodology to evaluate and calculate the transmissible torque of the HSK-E tool system based on FEM. Calculation method of the transmissible torque and building of the FEM analysis model was first introduced. Using the model to analyze the effect of the interference, spindle speed, and drawbar force on the stress distributions of the contact surfaces of toolholder-spindle interface, then the transmissible torque is finally calculated. The results show that the HSK-E tool system satisfies high speed cutting requirements provided that reasonable parameters of the interference and the drawbar force are designed.

Topic: Gear and Bearing Dynamics Analysis
Subfield: Mechanical Engineering
Field: Engineering
Domain: Physical Sciences
Problem issues between the countries of the European Union

It has been defined that the current state of the world development in the socio-economic and political terms is characterized by the rapid development of the integration processes in the world and, particularly, in Europe. For these reasons, the development of the European integration as well as the problems that arise in the European Union affect not only the countries which are members of the EU but also others, so the problems, which can be solved in the future, have been identified. The problems of capital migration, which influence the economic development of the countries and the factors of deep imbalance in the Eurozone have been investigated. It has been established that the European Union (EU) is a political and economic partnership consisting of 28 states. The EU is a unique formation in the system of world relations, which has a powerful economic and political force. The world integration processes that affect both external and internal factors have been singled out, it is indicated that the countries which once used to be the engine of the European integration, now significantly prevent it. The economic parameters of the European Union have been analyzed and their general problems have been highlighted, such as: the problem of ratification of the Constitution of the European Union; European sovereign debt crisis; the growth of populists, nationalist and anti-Western political parties support; the migration crisis and the withdrawal of Great Britain from the EU, called Brexit. The expediency of the European Union expanding as an objective process, which is connected with the globalization of the world economy, has been substantiated. The scenarios of the European Union development on the basis of the integration and prospects of countries in the Euro zone have been suggested.

Topic: Economic Issues in Ukraine
Subfield: General Economics, Econometrics and Finance
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Thermodynamic Properties of the Calcium Ferrites CaFe<sub>2</sub>O<sub>4</sub> and Ca<sub>2</sub>Fe<sub>2</sub>O<sub>5</sub>

The chemical potentials of CaO in the two-phase fields Fe2O3 + CaFe2O4 and CaFe2O4 + Ca2Fe2O5 of the pseudobinary system CaO - Fe2O3 have been measured in the temperature range from 975 to 1275 K, relative to pure CaO as the reference state, using solid state galvanic cells incorporating single-crystal CaF2 as the solid electrolyte. The cell was operated under pure oxygen at ambient pressure. The standard Gibbs energies of formation of calcium ferrites, CaFe2O4 and Ca2Fe2O5, were derived from the reversible emfs. The results can be summarized by the following equations:CaO + Fe2O3 --> CaFe2O4;Delta G degrees = - 37,480 + 1.16 T (+/- 250) J/mol 2 CaO + Fe2O3 --> Ca2Fe2O5;Delta G degrees = - 45, 280 - 13.51 T (+/- 275) J/mol These values are compared with thermodynamic data reported in the literature. The results of this study are in excellent agreement with heat capacity data, and in reasonable agreement with earlier measurements of enthalpy and Gibbs energy of formation, but suggest significant revision of enthalpies of formation of calcium ferrites given in current thermodynamic compilations.

Topic: Metallurgical Processes and Thermodynamics
Subfield: Mechanical Engineering
Field: Engineering
Domain: Physical Sciences
Large Deformations of an Elastic Solid

Abstract Hencky’s stress-strain relation for large deformations of a rubberlike material is reviewed. It is then applied to the specific cases of pure tension, compression, bending, shear, and torsion. Each of these cases is verified experimentally on samples made from natural rubber. Particular emphasis is placed on the shear and torsion analysis because of its importance to practical applications.

Topic: Elasticity and Material Modeling
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
#3971 INJURY INDUCED RENAL FIBROSIS PROMOTES CYSTOGENESIS AND CYST GROWTH IN ADULT MICE WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE

Abstract Background and Aims Acute kidney injury (AKI) is not a merely transient event, which can lead to a subsequent progression to chronic kidney disease (CKD). Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent inherited kidney disease caused by mutations in PKD1 or PKD2 gene. Previous studies showed that acute kidney injuries promote cystogenesis in adult mice with ADPKD. Fibrosis is a hallmark of AKI to CKD (AKI-CKD) transition, and positively correlated with renal cyst growth in humans. All these data imply a role of AKI-CKD transition in ADPKD.In this study, we aimed to determine the role of AKI-CKD transition in the ADPKD. Method We established AKI-CKD transition model by toxic or surgical injuries, and Pkd gene inactivation in adult mice was performed in different time point of AKI-CKD transition. The progression of renal fibrosis was shown by Western blotting analysis in toxic or surgical injury induced AKI-CKD transition model. Results We showed that renal injury before or after Pkd gene inactivation can both induce renal cyst formation in adult Pkd1 or Pkd2 mice, and the extent of cyst formation was correlated with the initial fibrosis level of three hits (injury and gene inactivation). Inactivation of Pkd1 gene at fibrosis recovery stage in surgery induced less cyst formation in adult Pkd1 mice. Enhanced renal fibrosis by repeated toxic injuries before gene inactivation accelerated renal cyst growth in Pkd1 mice. We further showed that the speed of cyst growth at the early stage in adult Pkd1 mice was decided by the baseline of renal fibrosis. Finally, we showed that conditional knockout of Ezh2 gene attenuated renal fibrosis and cyst growth in adult Pkd1 mice with established renal fibrosis. Conclusion Fibrotic responses in AKI-CKD transition is a driving force for renal cyst formation and growth in adult kidneys and inhibition of renal fibrosis through targeting EZH2 might be new therapeutic strategy for adult ADPKD.

Topic: Genetic and Kidney Cyst Diseases
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Sucking behaviour in 2-7 year old Swedish children - a pilot study

SAMMANFATTNING&#13;\n&#13;\nI västvärlden är förekomsten av sugvanor hög med en prevalens på 75 % till 95 % hos barn upp till 9 år. Om vanan fortsätter efter tre års ålder finns det risk för störningar i utvecklingen av käkarnas tillväxt och ocklusion. Tidigare studier har visat att det finns faktorer som är associerade med utvecklingen och durationen av en icke-nutritiv sugvana. Författarna till denna artikel tror att socioekonomisk status, familjeförhållanden och amning är faktorer som är associerade med utvecklingen av en förlängd sugvana. Dessutom kan det finnas ett samband mellan en förlängd sugvana och barns emotionella natur och deras språkutveckling. I denna studie undersöktes därför prevalensen av sugvanor och faktorer som är associerade med förlängda sugvanor i en grupp svenska barn mellan 2-7 år. &#13;\nFöräldrarna till 80 barn var konsekutivt utvalda på Allmän barn- och ungdomstandvårdsavdelningen på Odontologiska Fakulteten i Malmö och intervjuade från ett strukturerat protokoll under deras barns besök i tandvården. &#13;\nSjuttio procent av barnen i studien hade någon gång haft en sugvana. Resultaten visade ett positivt samband mellan att ha en förlängd sugvana, det vill säga en sugvana efter 4 års ålder, och att vara pojke, vara förstfödd, att mamman är svenskfödd eller har en universitetsexamen. En fjärdedel av föräldrarna till de barn med förlängda sugvanor uppgav problem i språkutvecklingen grund av den icke-nutritiva sugvanan. Barn med sugvanor uppgavs även oftare vara ledsna jämfört med barn utan sugvanor. Ökad kunskap om faktorer som är associerade med sugvanor ökar möjligheten att tidigt kunna identifiera de barn som löper risk att utveckla en förlängd sugvana och därmed på sikt förhindra en bettavvikelse.

Topic: Dental Anxiety and Anesthesia Techniques
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
The Fatherhood Factor: The Impact of the Father-Child Relationship on the Social, Interpersonal, and Recidivism Risk Factors of Previously Incarcerated Men

Doctoral Candidate, Larissa Aine Maley, has successfully defended and made the required modifications to the text of the doctoral dissertation for the Ph.D. during this

Topic: Homelessness and Social Issues
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
Persistent headache attributed to previous ischemic stroke: a prospective cohort study

Introduction Headache is a frequent sign of stroke, occurring both in the acute phase and persisting for 3 months after the stroke. The most recent International Classification of Headache Disorders has included persistent headache attributed to past stroke. Diagnosis depends on the presence of headache in the acute phase of stroke, although the headache persists for more than 3 months after the cerebrovascular event. Objectives To assess the incidence, course and impact of persistent headache attributed to a past ischemic stroke. To identify risk factors for the development of persistent headache attributed to a past stroke. Methods This was a prospective, observational cohort study. Inpatients with stroke, admitted within 72 hours of the onset of symptoms, were assessed at the Real Hospital Português de Beneficência de Pernambuco. Diagnosis of ischemic stroke occurred through the presence of an area of restricted diffusion in the magnetic resonance examination within a compatible clinical context. A semi-structured questionnaire was applied to characterize the sociodemographic information, the cerebrovascular disease and the headaches according to the diagnostic criteria of the International Classification of Headache Disorders. The NIHSS Stroke Scale and the HIT-6 scale were also used. Patients were assessed in person by the researchers in the acute phase of stroke and by telephone after 1 year to assess persistent headache attributed to past stroke. Results Initially, 221 patients were included, most of them male (59.3%) and whose mean age was 68.2 years ± 13.8. One hundred and nineteen patients (53.9%) answered the questionnaire by telephone 1 year after the stroke. Persistent headache attributed to a past stroke presented a frequency of 10.1% in the sample (95%CI: 5.3 to 17.0%) 1 year after the stroke. Headache presented a median frequency of 2.5 (1 – 4) days... (To see the complet abstract, please, check out the PDF.)

Topic: Cerebral Venous Sinus Thrombosis
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Potent and Selective 1,2,3-Trisubstituted Indole NPY Y-1 Antagonists

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTPotent and Selective 1,2,3-Trisubstituted Indole NPY Y-1 AntagonistsPhilip A. Hipskind, Karen L. Lobb, James A. Nixon, Thomas C. Britton, Robert F. Bruns, John Catlow, Donna K. Dieckman-McGinty, Susan L. Gackenheimer, Bruce D. Gitter, Smriti Iyengar, Douglas A. Schober, Rosa M. A. Simmons, Steve Swanson, Hamideh Zarrinmayeh, Dennis M. Zimmerman, and Donald R. GehlertView Author Information Lilly Research Laboratories, A Division of Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana 46285Cite this: J. Med. Chem. 1997, 40, 23, 3712–3714Publication Date (Web):November 7, 1997Publication History Received4 August 1997Published online7 November 1997Published inissue 1 November 1997https://pubs.acs.org/doi/10.1021/jm970512xhttps://doi.org/10.1021/jm970512xrapid-communicationACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views594Altmetric-Citations74LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Anions,Antagonists,Indoles,Peptides and proteins,Receptors Get e-Alerts

Topic: Neuropeptides and Animal Physiology
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Transition in growth mode by competing strain relaxation mechanisms: Surfactant mediated epitaxy of SiGe alloys on Si

Surfactant mediated epitaxy of Si(1−x)Gex alloys on Si(111) can, besides technological importance, clarify the influence of the lattice mismatch during surfactant mediated heteroepitaxial growth. For low Ge concentration we find an immediate layer-by-layer growth, whereas at high Ge concentration a roughening transition followed by relaxation of the lattice mismatch in a periodic dislocation network is preferred. This behavior can be explained by comparing the dislocation nucleation rate on a smooth surface with the island nucleation rate on a pseudomorphic film.

Topic: Semiconductor Quantum Structures and Devices
Subfield: Atomic and Molecular Physics, and Optics
Field: Physics and Astronomy
Domain: Physical Sciences