jimnoneill/paper-to-field-training huggingface dataset:
THE EFFECTIVENESS OF PROPRIOCEPTIVE NEUROMUSCULAR FACILITATION TECHNIQUES AND HIDROTHERAPY TO IMPROVE KNEE STABILITY AFTER ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION

Background Rehabilitation after anterior cruciate ligament reconstruction is a significant process which may decisively influence patient capacity to return to usual activity levels. Physiotherapy has a favourable influence on improving stability in the ACL deficient knee by using physical exercise and manual contact, the most affordable methods that can be used to improve quality of life. A combination of proprioceptive neuromuscular facilitation (PNF) tehniques and hydrotherapy is a treatment that can prevent stability loss and serve as an adjunct to conventional therapy. Purpose To compare the effect of adding a combination of PNF tehniques and hydrotherapy (research group) to a standard postoperative rehabilitation program (control group). Methods A total of fourty patients completed a standard rehabilitation program and in addition, twenty of them underwent 10-minute sessions of PNF tehniques and 15-minute sessions of hydrotherapy (34–36°C) each day, five days a week, for four weeks. Outcome measures including knee range of motion (ROM), manual muscle testing of flexors and extensors of the knee, functional assessment using Modified Cincinnati Knee Rating System (MCKRS), were assessed at baseline (initial assessment) and at four weeks (final assessment). Results The research group achieved significantly better results at the end of rehabilitation program compared with the control group. ROM of the reaserch group increased by 52.8° for flexion and 3.2° for extension, between the initial and final measurements in the injured knee. The corresponding changes for control group were 44° for flexion and 2° for extension. Extensor strength of the reaserch group increased by 40% and 22% for flexors, between the initial and final measurements in the injured knee, comparative to the control group where the increase was by 30% for extensors and 20% for flexors. The functional score with respect to the MCKRS, for the research group, improved by 36.4% between the initial and final measurements, whereas the corresponding changes for the control group were 25.8%. Conclusion PNF tehniques and hydrotherapy combined with standard rehabilitation program is effective at accelerating recovery after anterior cruciate ligament reconstruction.

Topic: Knee injuries and reconstruction techniques
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Detecting Privacy Preferences from Online Social Footprints: A Literature Review

Providing personalized content can be of great value to both users and vendors. However, effective personalization hinges on collecting large amounts of personal data about users. With the exponential growth of activities in social networking websites, they have become a prominent platform to gather and analyze such information. Even though there exist a considerable number of social media users with publicly available data, previous studies have revealed a dichotomy between privacy-related intentions and behaviours. Users often face difficulties specifying privacy policies that are consistent with their actual privacy concerns and attitudes, and simply follow the default permissive privacy setting. Therefore, despite the availability of data, it is imperative to develop and employ algorithms to automatically predict users’ privacy preferences for personalization purposes. In this document, we review prior studies that tackle this challenging task and make use of users’ online social footprints to discover their desired privacy settings.

Topic: Privacy, Security, and Data Protection
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
COMPUTATIONAL BIOLOGY APPROACH FOR THERAPEUTIC INTERVENTION OF ALEXANDER DISEASE BY POST TRANSCRIPTIONAL GENE SILENCING

Alexander disease (AxD) primarily affects the white matter of the central nervous system (CNS). It is an astrogliopathy in which Astroglial cells involved in maintenance homeostasis and providing defence to the brain are affected. Therefore their dysfunction has been implicated in a number of neurological, neuropsychiatric and neurodegerative disorders. GFAP (Glial fibrillary acidic protein) is the major intermediate filament protein present in astrocytes whose heterozygous missense mutations have been reported to be a cause of AxD. In the absence of any effective therapeutic intervention of AxD, in the present study PTGS (Post transcriptional gene silencing) approach to knock down mutant gfap gene. Various mutations causing AxD were checked for their pathogenicity using various in silico tools and 13 mutations were shortlisted based on their pathogenicity and probability of occurrence. Thereafter siRNA were designed against the mutant genes to silence them and thereby preventing the accumulation of mutant gfap that causes the pathophysiology of AxD.

Topic: RNA regulation and disease
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Play is play : theatrical illusion in Chinese wall by Frisch and other "epic" plays by Brecht, Wilder, Hazelton, and Li

Chapter 1 Introduction Chapter 2 Conceptional Foundations Chapter 3 The Theatrical Versus the Dramatic Chapter 4 Theater Is Theater Chapter 5 Play is Play Chapter 6 The Manipulation of Time in Epic Plays Chapter 7 Conclusion References Notes

Topic: Theatre and Performance Studies
Subfield: Visual Arts and Performing Arts
Field: Arts and Humanities
Domain: Social Sciences
End-to-end framework for QoS guarantee in heterogeneous wired-cum-wireless networks

With information access becoming more and more ubiquitous, there is a need for providing QoS support for communication that spans wired and wireless networks. For the wired side, RSVP/SBM has been widely accepted as a flow reservation scheme in IEEE 802 style LANs. In this paper, we investigate the integration of RSVP and a RSVP-like flow reservation scheme in wireless LANs, as an end-to-end solution for QoS guarantee in wired-cum-wireless networks. We propose WRESV, an RSVP-like flow reservation and admission control scheme for IEEE 802.11 wireless LAN. Using WRESV, wired/wireless integration can be easily implemented by cross-layer interaction at the access point. Main components of the integration are RSVP-WRESV parameter mapping, and the initiation of new reservation messages, depending on where senders/receivers are located. In addition, we also propose various optimizations for supporting multicast session, mobility management, and admission control.

Topic: Wireless Networks and Protocols
Subfield: Computer Networks and Communications
Field: Computer Science
Domain: Physical Sciences
Islamic Finance — An Overview

The sources of Islamic Finance are the Quran and Sunnah. These are the basic two sources from which conclusions regarding the authenticity of Islamic finance are considered. Islam itself is complete in all respects and therefore it has provided detailed guidelines for Islamic finance, either directly or indirectly, in a variety of different ways.

Topic: Islamic Finance and Banking Studies
Subfield: Accounting
Field: Business, Management and Accounting
Domain: Social Sciences
Changes in the Distribution of Plasma High Density Lipoproteins after Heparin-induced Lipolysis

The effect of heparin-induced lipolysis on the high density lipoprotein (HDL) subfractions was studied in 12 normotriglyceridemic patients (NTG) and 12 mildly hypertriglyceridemic patients (HTG). HDL2 and HDL3 were separated by ultracentrifugation before and 10min after heparin (10 units/kg of body weight) injection intravenously. In all subjects, there were negative correlations among the changes of VLDL- and HDL2-lipid levels after heparin injection. The changes of HDL2-lipid levels, except for triglyceride (TG), were inversely correlated with those of HDL3-lipid levels. These results supported that the conversion of HDL3 to HDL2 was induced during lipolysis of triglyceriderich lipoproteins (TGRLP) in vivo. In HTG, TG, free cholesterol (FC) and phospholipid (PL) in HDL2 increased significantly and esterified cholesterol (EC) and PL in HDL3 decreased significantly after heparin injection. In NTG, however, EC and PL in HDL2 decreased significantly and PL in HDL3 increased significantly after heparin injection. NTG differed from HTG in the heparininduced changes of HDL subfractions. In this experiment, it is not confirmed whether this difference is due to only the difference of TGRLP level between in NTG and HTG.

Topic: Diabetes, Cardiovascular Risks, and Lipoproteins
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
AN OPTIMISTIC THIRD PARTY PROTOCOL TO PROTECT A MOBILE AGENT'S BINARY CODE

In the world of mobile agents, security aspects are being discussed extensively, with strong emphasis on how agents can be protected against malicious hosts and vice versa. While in recent years many research groups presented solutions offering protection schemes for hosts that receive and run un-trusted, possibly malicious agents, in the field of protecting the agent against malicious hosts, development seems to grow very slowly. This paper discusses a protocol for detecting modifications at the agent's binary code that, for a particular class of modifications, undoubtedly unmasks the attacking host. Furthermore, it is shown that in co-operation with a special kind of route protection in a lot of scenarios the protocol resists attacks from coaliting malicious hosts as well as from a single malicious host.

Topic: Mobile Agent-Based Network Management
Subfield: Computer Networks and Communications
Field: Computer Science
Domain: Physical Sciences
Expansion of IR into the LSC region.

&lt;p&gt;The dashed lines depict the junction boundaries. The arrowed grey lines indicate the process of IR expansions. a, &lt;i&gt;Amborella&lt;/i&gt; and &lt;i&gt;Nicotiana&lt;/i&gt;; b, &lt;i&gt;Lemna&lt;/i&gt;; c, intermediate; d, &lt;i&gt;Acorus&lt;/i&gt; and &lt;i&gt;Dioscorea&lt;/i&gt;; e, date palm, &lt;i&gt;typha,&lt;/i&gt; and all Poaceaes; f, &lt;i&gt;Phalaenopsis&lt;/i&gt; and &lt;i&gt;Oncidium&lt;/i&gt;.&lt;/p&gt;

Topic: Wheat and Barley Genetics and Pathology
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
The Effect of Within Stimulus Presentation in Implicit Sequence Learning

The tacit and incidental acquisition of sequential information can occur in tasks from air-traffic control to crossing the streets in a crowded metropolis. The present study investigated how implicit sequence learning occurs when attention is divided amongst tasks. Our conceptualization of implicit sequence learning is that dual task interference arises from multiple control processes in the secondary task. This fits with findings that implicit learning remains intact when a within stimulus dual task is employed, where the stimulus for both tasks is incorporated within a single stimulus. However, a direct comparison with the standard dual task condition has not been presented. This comparison revealed another possible explanation for dual task interference in implicit sequence learning, that longer inter-trial intervals, a function of the within stimulus methodology, result in better performance and implicit learning. The data suggest that implicit learning and overall performance in a task that contains an incidental, consistent structure is optimized when stimuli are contained within a single stimulus.

Topic: Neural and Behavioral Psychology Studies
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Evaluation of active explosion suppression system for modern coal mining safety

The HS mine active suppression system,derived from military technology and based on intelligent high speed activation can provide an effective and practical method for the elimination of the devastating effects of a gas/coal dust explosion in a mining operation.This is a major breakthrough in gas/coal dust explosions prevention technology.

Topic: Safety and Risk Management
Subfield: Organizational Behavior and Human Resource Management
Field: Business, Management and Accounting
Domain: Social Sciences
Efficacy and safety of chemotherapy DCX (DOCETAXEL–CISPLATIN–CAPECITABINE) as a perioperative treatment of gastric cancer: A single institution analysis.

e16094 Background: Currently, ECF/ECX is the standard of care for peri-operative oesophagogastric adenocarcinoma (OGA), considering MAGIC trial even though the outcome still remains unsatisfactory with 36% 5-year overall survival (OS). FLOT4 trial proved superior results in OS and progression free survival (PFS) than ECF/ECX. The aim of our study is to check out the paper of taxane in perioperative setting as DCX schedule. Methods: Patients affected by OGA between 2008 to 2016 treated in our hospital with perioperative DCX were analyzed. Demographic, clinical, pathological and treatment characteristics were evaluated. We used the Kaplan-Meier method to generate curves for overall survival and time to progression (TTP). Results: Twenty-three patients were included. The median age at diagnosis was 64.13 years (46-75) and the male/female ratio was 1,3. The prevalence of primary location was antrum 21.7%, cardias Siewert II 4.3%, cardias Siewert III 26.1%, gastric body 43.5, linitis plastica 4.3%. Intestinal Laureen subtype was more common than diffuse subtype (39.1% vs 30.4%). 39.1% patients relapsed after surgery and the most common location was peritoneal (26.1%). Time admitted by surgery was 9.96 days (6-52). Time between end-of-chemotherapy and surgery was 48.3 days and time elapsed between surgery and postoperative chemotherapy was 45.8 days. Median OS data are not reached with current (34.69 months) follow-up, whereas a 65.5 months survival has been obtained with an immature evaluation. The median TTP was 15.79 months. Conclusions: Despite median OS data are still immature, they are superior than those obtained in FLOT4 trial and MAGIC trial. Further follow-up is required for more consistent data.

Topic: Gastric Cancer Management and Outcomes
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Morphometric and productive characteristics of sorghum genotypes for forage production in the Brazilian semi-arid

SUMMARY This study agronomically evaluated 14 sorghum genotypes in the Brazilian semi-arid region. A randomized complete block design, with the treatments represented by sorghum genotypes and three replicates, was used. The dry matter (DM), plant height (PH), number of live leaves, fresh matter production (FMP), dry matter production (DMP), leaf blade (LB), stem, panicle (PAN), dead material, water accumulation (WA), efficiency of rainwater use (ERU) and carrying capacity (SC) were measured. There was an effect of genotype among all the variables. The genotype with the highest percentage of DM was BRS 655 (26.42%). The genotypes BRS 655, BRS 506, B1141340, 13F04 (1141572) and PONTA NEGRA produced the most FMP, with values of 48,517, 48,500, 44,879, 44,788 and 43,549 kg/ha, respectively. Not only did the genotypes BRS 655, B1141340, 13F04 (1141572), BRS 506 and PONTA NEGRA present the highest DMP, with values of 12,426, 10,344, 9,778, 9,756 and 9,176 kg/ha, respectively, but also the highest values for ERU, WA and SC. There was a significant positive correlation between productive variables (FMP with DMP, PH, ERU and WA) and a nonsignificant negative correlation between morphometric variables (FMP with LB and PAN). A hierarchical formation of four groups was observed, with groups I and III composed of the most productive genotypes. BRS 655 can be recommended for cultivation since this genotype has desirable agronomic characteristics.

Topic: Agroforestry and silvopastoral systems
Subfield: Forestry
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Decline in Breast-feeding: What are the factors responsible?

Objective: Breast-feeding is on decline (1,2). The objective of this study is to determine factors responsible for discontinuation of continued breast-feeding among mothers. Design: Community-based, Descriptive and cross sectional household survey. Place and Duration of Study: This study was carried out in different localities of urban area of city, Dera Ismail Khan during month of July 2003. Subjects and Methods: It is cross-sectional study, interviewing one hundred and seventy six samples consisting of mothers who discontinued breastfeeding before 2 years. Questionnaire was constructed on basis of focuss group discussion. Informations was collected and then analyzed. Statistical Analysis: Descriptive statistical methods. Results: The result of this mini-survey showed a major reason behind the discontinuation of breastfeeding at early period is having not enough milk in their breasts (54%). The second major reason say that their babies were not feeling well after receiving their breast milk (23%). Other reasons discovered in this study is that their babies were still feeling hungry after breast fed (10%), difficult to give enough time for lactation as doing work outside home (6%), fear of loss of physical attraction (4%) and milk dried up (3%). Conclusion: Breastfeeding is important determinant of nutritional status of child which in turn influences growth and development of child. In future, breastfeeding promotion campaign may include stress on continued breastfeeding and underlying barriers as explored in this study should be fully addressed.

Topic: Breastfeeding Practices and Influences
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
[The effect and safety of tirofiban on acute ST segment elevation myocardial infarction patients receiving no early reperfusion therapy].

Tirofiban did not increase initial patency in STEMI patients without early reperfusion therapy. However, it can improve myocardial perfusion after PCI.

Topic: Acute Myocardial Infarction Research
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Formatting a Proactive Principal Preparation Program in Response to the National Reform Movement in Education Administrative Preparation.

This paper discusses a preparatory program for educational leaders at the University of Southern Mississippi (USM). The report outlines the numerous calls for reform of preparatory programs and focuses on the four factors motivating reform efforts: a move away from a managerial to a human-centered perspective; a continued orientation on the importance of a knowledge base that is best learned via traditional academic preparation; a strengthening orientation on learning by doing; and a renewed orientation on the importance of personal professional characteristics of the administrator. These factors served as a general philosophical framework upon which the USM program was based. The program was conceptualized to reflect essential, significant shifts in the basic premises on which schools and leaders have operated, most importantly the development of proactive principals. The paper offers information on the organization and sequencing of integrated curriculum blocks for the program, the instructional procedures and methodology, the assessment of students, and the assessment of the program. It is stated that the new reform program has brought together a number of ideas, models, and delivery formats to create a totally different approach from that which has been in operation at USM. (Contains approximately 112 references.) (RJM) ******************************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. ********************************************************************************

Topic: Teacher Education and Leadership Studies
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Anterior Cruciate Ligament Reconsruction using Tibialis Tendon Allograft - Comparison of the Results according to the Femoral Fixation Methods -

Resul ts : Twenty-eight patients (90.3% ) in group I and 33 (91.7% ) in group II were good or excellent according to the Lysholm score. T wenty-seven patients (87.1% ) in group I and 33 (91.7% ) in group II had IKDC subjective knee score ＞70. Thirty patients (96.8%) in group I and 35 (97.2)% in group II had 1+firm end or negative Lachman test. Twenty-seven patients (87.1%) in group I and 35 (97.2%) in group II had a negative pivot shift. Thirty patients (96.8% ) in group I and 36 (100% ) in group II had ＜5 mm of difference according to the KT-1000 arthrometer. Twenty-nine patients (93.5%) in group I and 34 (94.4%) in group II were normal or nearly normal according to the 2000 IKDC knee examination. Concl u si o n: AC L reconstruction with fresh-frozen tibialis tendon allograft produced a reliable and predictable outcome after the short-term follow-up. The two methods used for femoral fixation produced similar outcomes.

Topic: Knee injuries and reconstruction techniques
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
The Role of BRDT in Esophageal Squamous Cell Carcinoma

Esophageal squamous cell carcinoma (ESCC), the predominant subtype of esophageal cancer, remains a deadly malignancy due to the lack of effective therapies. Precision oncology, utilizing various techniques to identify patient-specific vulnerabilities for therapeutic intervention, has emerged as a promising approach for cancer treatment. Many clinical trials involving EGFR-targeted therapies in ESCC have failed, highlighting a need for the identification of novel therapeutic targets. Epigenetic alteration is one of the hallmarks of cancer and epigenetic factors are also widely dysregulated in ESCC. In this project, we sought to identify a therapeutic target for advancing precision medicine in ESCC. Using an unbiased method, we screened a curated list of epigenetic factors and found that a testis-specific epigenetic reader protein BRDT to be expressed and functional active in a significant portion of ESCC patients. While it does not affect cell proliferation, it is essential for cell migration. Transcriptomic profiling revealed extracellular matrix-related pathways are altered upon loss of BRDT, which could explain the decreased migratory potential. Chromatin occupancy profiling of BRDT uncovered its preferential occupancy of active promoters and enhancers. Subsequently, we found that genes dependent on BRDT are also targets of ΔNp63, a master transcription factor for squamous lineage commitment. Besides the common target genes, genomic co-localization of BRDT and ΔNp63 confirms the functional interplay between them. Knock-down of ΔNp63 or FAT2, a common target of BRDT and ΔNp63, phenocopies the loss of BRDT. Furthermore, overexpression of BRDT in a BRDT-negative ESCC cell line can enhance the expression of the ΔNp63-dependent gene expression program and significantly increase cell migration. To gain more mechanistic insight, we integrated chromatin topology data with epigenome profiles and found that BRDT and ΔNp63 co-localize at selected super enhancers to regulate ΔNp63-dependent transcription programs that promote cell migration. Strikingly, pharmacologically depleting BRDT recapitulates the effects of BRDT depletion. Collectively, these findings revealed the role of BRDT in ESCC and uncover the potential of BRDT as a novel therapeutic target for precision medicine in a subset of ESCC.

Topic: Cancer-related gene regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences