jimnoneill/paper-to-field-training huggingface dataset:
Na Cocations and Hydrothermal Aging Cooperatively Boost the Regeneration of Phosphorus-Poisoned Pd/SSZ-13 for Passive NO<sub><i>x</i></sub> Adsorption

Pd/SSZ-13 has been proposed as a passive NO<sub><i>x</i></sub> adsorber (PNA) for low-temperature NO<sub><i>x</i></sub> adsorption. However, it remains challenging for Pd/SSZ-13 to work efficiently when suffering from phosphorus poisoning. Herein, we report a simple and efficient strategy to regenerate the phosphorus-poisoned Pd/SSZ-13 based on the cooperation between hydrothermal aging treatment and Na cocations. It was found that hydrothermal aging treatment enabled the redispersion of Pd and P-containing species in phosphorus-poisoned Pd/SSZ-13. Meanwhile, the presence of Na cocations significantly reduced the formation of AlPO<sub>4</sub> and retained more paired Al sites for highly dispersed Pd<sup>2+</sup> ions, which was of great importance for the recovery of adsorption performance. To our satisfaction, the restoration ratio of the adsorption capacity of poisoned Pd/SSZ-13 was >90% after regeneration. Strikingly, the NO<sub><i>x</i></sub> adsorption activities of phosphorus-poisoned Pd/SSZ-13 with phosphorus loadings of 0.2 and 0.4 mmol g<sup>-1</sup> almost completely recovered upon regeneration. This study demonstrates the promoting effect of Na cocations on the regeneration of phosphorus-poisoned Pd/SSZ-13 by hydrothermal aging treatment, which provides useful guidance for the design of PNA materials with excellent durability for cold-start application.

Topic: Catalytic Processes in Materials Science
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Video from SRSF2 Regulation of &lt;i&gt;MDM2&lt;/i&gt; Reveals Splicing as a Therapeutic Vulnerability of the p53 Pathway

&lt;p&gt;3D rendering of 60X confocal images taken of SRSF2 (green) and SRRM2 (red) coimmunofluorescence in HeLa S3 cells after 0 hours of UVC treatment. Colocalization channel is indicated by magenta color, while the blue color represents the nucleus stained with DAPI.&lt;/p&gt;

Topic: Cancer-related Molecular Pathways
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Electrophysiological effects of mucosal Cl- removal in Necturus gallbladder epithelium

The factors responsible for the cell membrane hyperpolarization elicited in Necturus gallbladder epithelium on Cl- removal from the mucosal bathing solution were evaluated with conventional and ion-sensitive microelectrode techniques. Cl- removal causes reversal of apical Cl- -HCO3- exchange, resulting in a fall in intracellular Cl- activity (aiCl) and an increase in intracellular pH (pHi). Concomitantly, the cell membranes hyperpolarize to values close to the K+ equilibrium potential (EK), aiNa falls, and aiK rises. The observed changes in membrane voltage are not attributable to a pHi-dependent increase in cell membrane K+ permeability (PK), because 1) the cell membrane resistances increased and 2) elevating solution partial pressure of CO2 (PCO2) to counterbalance the cellular alkalinization on mucosal Cl- removal caused a further hyperpolarization of the cell membranes to values greater than EK. This additional hyperpolarization was related to the activity of the Na+ pump, inasmuch as it was accompanied by an increase in aiNa and was ouabain sensitive. These results are consistent with, but do not prove, pump electrogenicity. During the period of Cl- removal from the mucosal bathing solution, the cell membrane depolarization caused by raising serosal K+ concentration was increased, whereas the depolarization caused by lowering serosal Cl- concentration was decreased, compared with substitutions under control conditions. These results indicate that mucosal Cl- removal causes a decrease in basolateral PCl, which we speculate could be due to a decrease in cell volume. We conclude that the hyperpolarization of the cell membranes on mucosal Cl- removal is primarily due to the combined effects of the fall in basolateral PCl and the increase in basolateral ECl.

Topic: Ion channel regulation and function
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Disneyworld.com redesign

Disneyworld.com has recently been redesigned from the ground up. This paper discusses the challenges facing the design team given the enormous and unique physical aspects of the property, a very challenging business climate for the travel industry in the post-911 world, and the need to uphold the magical imperative of the world's pre-eminent entertainment brand.Our solution needed to address two very specific and disparate groups of users: "Intenders" and "Repeaters". It needed to enfranchise new back-end systems and commerce processes. And it needed to tie into Walt Disney World's® overarching CRM initiative.The design solution is a holistic and scalable experience, allowing Guests to navigate via geographic and/or experience-based facets, incorporating a vast array of multimedia assets. Although the site has only been live for a little over a month, the early results are overwhelmingly positive.

Topic: Digital Games and Media
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
New earthworms of the Pheretima urceolata species group (Oligochaeta: Megascolecidae) from southern Luzon, Philippines

Hong, Yong, James, Samuel W. (2009): New earthworms of the Pheretima urceolata species group (Oligochaeta: Megascolecidae) from southern Luzon, Philippines. Zootaxa 2059: 33-45, DOI: 10.5281/zenodo.186796

Topic: Invertebrate Taxonomy and Ecology
Subfield: Ecology, Evolution, Behavior and Systematics
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Absolute Music and Contingent Music: A Theoretical Framework

Although music is often talked about as having one political agenda or another, in Western art music these features are generally thought to be distinct from the "music itself." As straightforward a proposition as this might seem to a reader fully acculturated to the contemporary music ideology, it is not the only possible way of conceiving of music as a social force. There exists music whose aesthetic merits are completely indistinguishable from its social function. More accurately, there exists an attitude about music in which it is not thought of as occupying a separate sphere with autonomous aesthetic principles. This paper creates a theoretical framework with these two attitudes at its extremes: absolute music and what I shall call "contingent" music. This theoretical framework has interesting historical antecedents, and is a useful way of thinking about some of modern music's ideological conflicts. It is also an important part of my own work as a composer, and this paper concludes by describing the way in which the absolute-contingent opposition informs three of my own compositions.

Topic: Musicology and Musical Analysis
Subfield: Music
Field: Arts and Humanities
Domain: Social Sciences
1177 Multi-Drug Immunosuppression Post-Solid Organ Transplantation Is Associated With Increased Enteric Infection on Multiplex Gastrointestinal Pathogen PCR Testing

INTRODUCTION: Diarrhea is a common sequela of solid organ transplantation. Post-transplant diarrhea may be attributed to non-infectious causes including medications, however the contribution of infectious etiology is unclear. The objective of our study was to evaluate the relationship between post-transplant immunosuppression and enteric infection as detected by multiplex gastrointestinal PCR stool testing in solid organ transplant (SOT) recipients. METHODS: We performed a multicenter cross-sectional analysis of inpatient and outpatient SOT recipients who underwent stool testing with a FilmArray multiplex gastrointestinal pathogen PCR panel (GI PCR panel) during an acute episode of diarrhea from April 2016 to May 2019. The primary endpoint was the detection of any enteric pathogen. Patients were stratified by the number of major classes of immunosuppressive agents, including calcineurin inhibitors, anti-proliferative agents, and corticosteroids, at time of stool testing. RESULTS: We identified 232 SOT patients who underwent a GI PCR panel comprising 52 (23%) lung, 84 (36%) kidney, 41 (18%) heart, and 55 (24%) liver transplants. 92 (40%) tested positive for an enteric pathogen. Patients whose immunosuppressive regimen included 3 medications (n = 139) were more likely to have a gastrointestinal pathogen detected (63, 45%) compared to patients on 2 immunosuppressive medications ( P = 0.02; Figure 1) Renal transplant patients were more likely to have an enteric pathogen detected (60%; P &lt; 0.0001) compared to other organ types, and more likely to be on 3 immunosuppressive medications ( P &lt; 0.01). Viruses, specifically norovirus and sapovirus, and bacteria, including C. difficile and E. coli subtypes, were common in transplant recipients on 2 immunosuppressive agents (Table 1). Of 139 patients on 3 immunosuppressive agents, 89 (59%) were more likely to be on opportunistic infection prophylaxis for CMV and P. jirovecii pneumonia compared to those patients on 2 drugs ( P &lt; 0.001). In the 30 days following stool testing, all SOT recipients, regardless of the number of immunosuppressive drugs, were as likely to visit an emergency room ( P = 0.57), require hospitalization ( P = 0.66), or undergo endoscopic procedures for persistent GI symptoms ( P = 0.78). CONCLUSION: Gastrointestinal infections, particularly enteric viruses, were common in SOT recipients who underwent a GI PCR panel for an episode of post-transplant diarrhea, with the highest proportion of positive results in patients maintained on 3 or more immunosuppressive agents.

Topic: Cytomegalovirus and herpesvirus research
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
(Un)Conditional surrender? Why do professionals willingly comply with managerialism Mats Alvesson

Purpose – The purpose of this paper is to explore the question – why do professionals surrender their autonomy? This paper looks at the case of academics, in particular business school academics. It traces how this group of professionals have progressively surrendered their autonomy and complied with the demands of managerialism. Design/methodology/approach – This largely theoretical paper looks to develop an understanding of (over)compliance with the bureaucratization of research using the four faces of power – coercive, agenda setting, ideological and discursive. Findings – The discussion of this paper argues that the surrendering of autonomy has been reinforced through coercive forms of power like rewards and punishment and bureaucratization; manipulation and mainstreaming through pushing a particular version of research to the top of the agenda; domination through shaping norms and values; and subjectification through creating new identities. Originality/value – The paper explores how academics deal with tensions and paradoxes such as compliance and resistance, as well as love of work and loathing of it. To deal with these paradoxes, academics often treat their work as a game and see themselves as players. While this process enables academics to reconcile themselves with their loss of autonomy, it has troubling collective outcomes: the production of increasing uninteresting and irrelevant research.

Topic: Management and Organizational Studies
Subfield: Organizational Behavior and Human Resource Management
Field: Business, Management and Accounting
Domain: Social Sciences
Finite Element Analysis and Deformation Homogeneity Optimization of Constrained Groove Pressing

Improvement of materials properties induced by constrained groove pressing (CGP) depends largely on deformation homogeneity. Utilizing commercial software DEFORM-3D, a finite element model of multi-pass CGP was established. The distribution and homogeneity evolution of equivalent strain ware analyzed in detail. Based on Taguchi optimization method, the influence of processing parameters (such as groove width, groove angle, friction coefficient and deformation rate) on strain homogeneity was studied numerically and systematically. Within a certain range, the optimum parameter combination is obtained by means of signal to noise ratio analysis. The inhomogeneity factor of the optimum model decreases by about 50 %. The average accumulative equivalent strain is almost twice that of the initial model. Analysis of variance shows that groove angle and groove width are the two most important parameters and effect of friction between dies and sample should not be neglected.

Topic: Microstructure and mechanical properties
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Insights into Transfer Learning between Image and Audio Music Transcription

Optical Music Recognition (OMR) and Automatic Music Transcription (AMT) stand for the research fields that devise methods to transcribe music sources---documents or audio signals, respectively---into a structured digital format. Historically, they have followed different approaches to achieve the same goal. However, their recent definition in terms of sequence labeling tasks gathers them under a common formulation framework. Under this premise, one may wonder if there exist any synergies between the two fields that could be exploited to improve the individual recognition rates in their respective domains. In this work, we aim to further explore this question from a Transfer Learning (TL) point of view in the context of neural end-to-end recognition models. More precisely, we consider a music transcription system, trained on either image or audio data, and adapt its performance to the unseen domain during the training phase using different TL schemes. Results show that knowledge transfer slightly boosts model performance with sufficient available data, but it is not properly leveraged when the latter condition is not met. This opens up a new promising, yet challenging, research path towards building an effective bridge between two solutions of the same problem.

Topic: Music and Audio Processing
Subfield: Signal Processing
Field: Computer Science
Domain: Physical Sciences
CCDC 1411999: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
PHARMACY HEALTH SYSTEM IN CANADA: AN ADOPTABLE MODEL FOR ADVANCED CLINICAL AND PHARMACEUTICAL CARE

The philosophy of patient care is a wide and complicated topic of literature. That is elaborated by different health institution to harmonize their local clinical activities. Undoubtedly, that is working successfully to satisfy patients, fulfill the requirement of clinicians and cover maximum mutual benefits within officially allocated budget. However, patient care has different comprehension in different demographic and socio-political setting. But, in general, the meaning, understanding and composition of clinical and pharmaceutical patient care may be same all over world. The pharmacists, clinicians and administration adopt, exercise and emphasize on certain parts depending upon the type of challenges, kind of patients and available health care facilities. Thus, the health care is an emerging field that always remained under consideration. The local and international experts like to work, contribute and improve it to enhance the public health. Even some time judiciary, parliament and local intelligentsia focus and emphasize to address some particular health related problems. So, we may need to elaborate the comprehension to satisfy the literature and logical need of health and medicine including identification of problems, designing treatment protocol and handling the complication of therapy. That may potentially improve the overall outcomes and maximize the patient’s benefit. After twenty five years the definition of pharmaceutical care is still unsatisfactory. The confusion remained about what this term comprises and how to distinguish it from other terms. The board of the Pharmaceutical Care Network Europe (PCNE) felt essential to rephrase pharmaceutical care and to answer the question: "What is Pharmaceutical Care ". The patient care is not perfectly incorporated into the health care system in most part of the world. However, pharmacy practice has shown positive attitudes toward patient care provision. Thus, an advanced working should focus to improve the understanding the concept of patient care and overcome barriers.

Topic: Pharmaceutical Practices and Patient Outcomes
Subfield: Geriatrics and Gerontology
Field: Medicine
Domain: Health Sciences
High Commissioners as Scholarly Observers: Crocker on Nehru, and Grant on Indira Gandhi

This chapter focuses on two Australian high commissioners in other than their official roles.Such a task is made possible by two incumbents leaving a legacy of writing about their respective times in situ, and writing about Indian leaders in particular.The two high commissioners who left strong written records, the kind of records that enable us to say that their legacies endured well beyond their times in New Delhi, were Walter Crocker (1952-55 and 1958-62) and Bruce Grant (1973-76).What follows is an analysis of Crocker's and Grant's sketches of Indian leaders, Nehru and Indira Gandhi, respectively, with a view to addressing the more general questions around

Topic: Indian History and Philosophy
Subfield: Philosophy
Field: Arts and Humanities
Domain: Social Sciences
Oxygen saturation in the supine hypotensive syndrome.

This study used recently available, continuous noninvasive monitoring techniques to evaluate positional variations in pulse, blood pressure, and maternal oxygen saturation in 42 women undergoing fetal nonstress testing in the third trimester. Ten nonpregnant women were similarly evaluated with the automatic sphymomanometer and pulse oximeter. Six of 42 pregnant women (14.3%) developed the supine hypotensive syndrome (defined as a mean blood pressure decrease of 15 mmHg and a sustained increase in pulse of 20 beats per minute) when in the supine position. Nine of them (21.4%) met at least one of the criteria, but the majority (27 of 42, 64.3%) met neither criterion. None of the ten nonpregnant subjects had hypotension or tachycardia, although nine demonstrated blood pressure elevation after assuming the supine position. Significant oxygen desaturation did not occur in any patient, although three of six hypotensive patients had a transient 3-5% desaturation after supine rest. This study confirms that a significant percentage of patients in the third trimester are affected to some degree by supine hypotension. However, significant oxygen desaturation does not appear to occur.

Topic: Neonatal Respiratory Health Research
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Target Centred Virtue Ethics and Role Ethics

Abstract The development of ‘virtue jurisprudence’ (a neo-Aristotelian virtue ethics for law) has highlighted the importance of virtue in legal ethics. Yet it has been criticized because it cannot account for “robust” role differentiation. In this chapter I argue that Target Centred Virtue Ethics can account for two features which constitute the ‘Role Dilemma’: (a) There is robust role differentiation; that is, role differentiation as conceived by the Standard Conception of law (and, e.g., business).(b) Occupiers of legal roles are not permitted to act immorally (except perhaps in “tragic” dilemmas).Virtue ethics and Standard Conceptions of law (and, e.g., business) are standardly thought to be incompatible. This may be true where virtue ethics is conceived in “orthodox” neo-Aristotelian terms. I reject this version of virtue ethics for role ethics and show that Target Centred Virtue Ethics can subscribe to both horns of the dilemma (a) and (b) above.

Topic: Psychology of Moral and Emotional Judgment
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
[Freud's letters as a historical source].

This article introduces the project of a "concordance of letters to and by Freud". It should make the broadly scattered Freud-correspondence more accessible to the historian. (Since the death of Freud, almost 3200 letters written by him and nearly 1200 letters to him have been published.) At the same time principles of methodology are discussed which have to be observed in using letters as historical source material.

Topic: Psychology and Mental Health
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Molecular Modeling, Cheminformatics Analysis, and Synthesis of Trifluoromethylated Aromatic Sulfonamides as Putative Inhibitors of Cholesteryl Ester Transfer Protein

Abstract Elevated lipid profile is a major risk factor for diseases like dyslipidemia. Cholesteryl ester transfer protein (CETP) inhibitors are explored for their potential to raise HDL and lower LDL, offering a promising approach to reducing cardiovascular risk. In this study, a series of ortho ‐ and meta ‐trifluoromethylated sulfonamides 6a‐6t were synthesized and evaluated for their CETP inhibitory activity at 10 µM concentration. Compounds 6a‐6t featured various aromatic substituents, positioned at different sites. Results revealed that compound 6f demonstrated the highest inhibitory efficacy, achieving a 100% inhibition. CETP inhibition was compared to computational models Hypo‐1 and Hypo‐1‐shaped to predict potential biological efficacy. The findings indicate that electron‐withdrawing groups, particularly Cl and NO₂, significantly enhance CETP inhibitory potency, especially when located at the ortho or meta positions. These compounds exhibited a strong correlation between Hypo‐1 activity and % inhibition, suggesting improved interaction with CETP. In contrast, methyl electron‐donating substitutions resulted in lower activity, indicating their inadequacy for this scaffold. Further cheminformatics analyses based on molecular descriptors indicated that 6f has enhanced lead‐like and drug‐like properties in comparison to the second most potent compound 6i (82%). Developing new compounds with CETP inhibitory properties shows promise for future interventions to regulate lipid profiles.

Topic: Computational Drug Discovery Methods
Subfield: Computational Theory and Mathematics
Field: Computer Science
Domain: Physical Sciences
A Competency Approach to Healing “Past Life Trauma”

Abstract Traces the use of competency-based counseling to relieve chronic headaches attributed by the client to physical, sexual and psychospiritual trauma suffered in past lives. Treatment focused on the skills and resources the client could bring to bear on her problem. Case study includes commentary by the counselor and comments from the client six months after treatment. Treatment consisted of 10 sessions over a five-month period, and the client reported sustained improvement six months after counseling ended. Competency-based counseling uses theory and technique from solution-focused brief therapy, narrative therapy, and O'Hanlon's possibility therapy to move clients toward their goals as quickly as possible.

Topic: Psychotherapy Techniques and Applications
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Nanostructured layers for optical coatings with improved UV-transmission

Nanostructured low-index layers are produced on glass and plastics by coating and plasma-etching of organic and inorganic materials. The organic content was reduced afterwards to achieve antireflective coatings with increased UV-transparency.

Topic: Optical Coatings and Gratings
Subfield: Surfaces, Coatings and Films
Field: Materials Science
Domain: Physical Sciences