jimnoneill/paper-to-field-training huggingface dataset:
Juglone 4-Monooxime, an Isomer of 8-Nitro-1-naphthol

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTJuglone 4-Monooxime, an Isomer of 8-Nitro-1-naphtholD. C. Morrison and D. W. HeinritzCite this: J. Org. Chem. 1962, 27, 6, 2229–2231Publication Date (Print):June 1, 1962Publication History Published online1 May 2002Published inissue 1 June 1962https://pubs.acs.org/doi/10.1021/jo01053a517https://doi.org/10.1021/jo01053a517research-articleACS PublicationsRequest reuse permissionsArticle Views80Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Topic: Axial and Atropisomeric Chirality Synthesis
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
New North American Tabanidae (Diptera) III. Notes on Tabanus molestus and Related Horseflies with a Prominent Single Row of Triangles on the Abdomen

Stone (1938), in his monograph of the Nearctic species, has provided the most recent improvement in understanding of Tababus s. str. with a single row of pale triangles on the abdomen. Certain of these have shown most confusing variations and still are difficult in some cases to identify. The present paper aims to supplement his able treatment and provide certain new information.

Topic: Insect behavior and control techniques
Subfield: Insect Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Mechanical Properties of the Vertical Joints of Prefabricated Underground Silo Steel Plate Concrete Wall

Reliable joint connection is key to designing prefabricated structures. To study the mechanical properties of the vertical joints in the designed prefabricated underground silo steel plate concrete composite wall and verify their reliability, flexural and compressive experiments were conducted using two groups of six full‐scale steel plate concrete composite wall specimens; the mechanical properties between jointed and jointless specimens were compared and analyzed. The experimental results indicate that all specimens are in the elastic stage during the entire loading process; further, they exhibit large stiffness and high bearing capacity without damages. Thus, the designed vertical joints of the steel plate concrete composite wall provide a reliable connection that is safe and applicable. Further, the flexural and compressive properties of jointed and jointless specimens were found to be similar; the newly designed prefabricated underground silo steel plate concrete composite wall could be designed using the “equivalent principle” that the combined wall design calculation with the joint could be equivalent to that without the joint.

Topic: Structural Load-Bearing Analysis
Subfield: Civil and Structural Engineering
Field: Engineering
Domain: Physical Sciences
Wavefront preserving and high efficiency diamond grating beam splitter for x-ray free electron laser

X-ray free electron lasers (XFELs) provide femtosecond high-power x-ray beams with high spatial coherence, resulting in numerous influential discoveries. Diffractive optics allow for the easy manipulation and measurement of an x-ray beam’s wavefront and enable the realization of complex designed properties and specifications. For example, phase gratings can be used as x-ray beam splitters to enable beam sharing by multiple end stations or in-situ beam monitoring, including spectrum and wavefront measurements. Wavefront preservation and high efficiency and survivability under high power are requirements for such beam splitters. Diamond is the most suitable choice for phase grating fabrication, due to its high thermal conductivity that enables it to survive high average power XFEL beams. We have fabricated a large area (2×2 mm 2 ) high aspect ratio (13:1) diamond grating on a diamond plate. Testing was performed at 9.5 keV and resulted in a high splitting efficiency (30%). Tunable efficiency was obtained via tilting the grating with respect to the x-ray beam. Wavefront fidelity of the split beams were measured to less than λ /100 using a Talbot wavefront sensor.

Topic: Advanced X-ray Imaging Techniques
Subfield: Radiation
Field: Physics and Astronomy
Domain: Physical Sciences
SORT: A Self-ORganizing Trust Model for Peer-to-Peer Systems

Open nature of peer-to-peer systems exposes them to malicious activity.Building trust relationships among peers can mitigate attacks of malicious peers.This paper presents distributed algorithms that enable a peer to reason about trustworthiness of other peers based on past interactions and recommendations.Peers create their own trust network in their proximity by using local information available and do not try to learn global trust information.Two contexts of trust, service, and recommendation contexts, are defined to measure trustworthiness in providing services and giving recommendations.Interactions and recommendations are evaluated based on importance, recentness, and peer satisfaction parameters.Additionally, recommender's trustworthiness and confidence about a recommendation are considered while evaluating recommendations.Simulation experiments on a file sharing application show that the proposed model can mitigate attacks on 16 different malicious behavior models.In the experiments, good peers were able to form trust relationships in their proximity and isolate malicious peers.

Topic: Access Control and Trust
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Polyphenol Composition of Extracts of the Fruits of Laserpitium Krapffii Crantz and Their Antioxidant and Cytotoxic Activity

During inflammation, reactive oxygen species (ROS) are produced in large amounts, causing oxidative stress. Several studies confirm that plant extracts rich in phenolic compounds may inhibit ROS production. For that reason, the aim of this work is the qualitative and quantitative analysis of phenolic acids and flavonoids in the etheric (LAEN) and methanolic (LAM) extracts of the fruits of Laserpitium krapffii Crantz, as well as their antioxidative and cytotoxic properties. Liquid chromatography–electrospray tandem mass spectroscopy (LC-ESI-MS/MS) enabled the identification of 12 phenolic acids and nine flavonoids. Both tested extracts scavenged ROS in a concentration-dependent manner. Stronger activity was observed for the methanolic extract. The cytotoxic effect of both extracts in increasing concentrations on five types of cancer cell lines was also investigated. The cytotoxicity was estimated using trypan blue vital staining. It was found that the analyzed extracts induced the apoptosis of the cells of all the tested cell lines. In conclusion, our results present that the fruits of L. krapffii can be a source of valuable compounds with protective effects against oxidative damage.

Topic: Natural product bioactivities and synthesis
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Application of fuzzy inference to electric load clustering

In distribution system, bus load estimation is complicated because system load is usually monitored at only a few points. As a rule receiving nodes are not equipped with stationary measuring instruments so measurements of loads are performed sporadically. In general, the only information commonly available regarding loads, other than major distribution substations and equipment installations, is billing cycle customer kWh consumption. In order to model system uncertainty, inexactness, and random nature of customers' demand, a fuzzy system approach is proposed. This paper presents application possibilities of the fuzzy inference method to the electrical load modeling. Clustering of load profiles in different part of system was used to classify the substations. A regression model, expressing the correlation between a substation peak load and a set of customer features (explanatory variables), existing in the substation population, is determined. Simulation studies have been performed to demonstrate the efficiency of the proposed scheme and an effect of different parameters on its accuracy on the basis of actual data obtained at distribution system substations

Topic: Energy Load and Power Forecasting
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Diffusion in polymer‐solvent systems

Abstract Recent advances in the area of molecular diffusion in polymer‐solvent systems will be reviewed. Alfrey's classification scheme for the diffusion of solvent molecules in polymers will be used as a starting point. It will be shown that the various regions on Alfrey's diagram are distinguished by the ratio of two characteristic times, a characteristic relaxation time for the polymer‐solvent system and a characteristic diffusion time. Fickian diffusion is realized when this characteristic ratio is a small number, and anomalous behavior occurs when these two characteristic times are the same order of magnitude. Alfrey's “null” region corresponds to those conditions where this dimensionless ratio is much greater than one. The different manifestations of anomalous diffusion with polymer‐solvent systems will be discussed, including case II transport as defined by Alfrey, Gurnee, and Lloyd. Finally, diffusion in polymer‐solvent systems above the glass transition temperature where classical diffusion theory is applicable will be considered. Emphasis will be placed on the demonstration of the ability of theoretical methods based on free volume concepts to predict the concentration and temperature dependencies of diffusion coefficients. The extension of this free volume theory to describe diffusion in glassy polymers will also be demonstrated. Experimental results for several polymer‐solvent systems which exhibit different types of transport behavior will be used to illustrate the correlative and predictive capabilities of these recently developed theories.

Topic: Material Dynamics and Properties
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
An investigation of barriers and facilitators of coordination between primary palliative care and specialized palliative care in Switzerland: a qualitative study

Successful palliative care (PC) is determined by the collaborative approach of health care professionals. Importantly, the coordination of PC services across different institutions and health care settings plays a crucial role for collaborative approaches in PC. Coordination of services in PC is especially required between Primary Palliative Care (PPC) and Specialized Palliative Care (SPC). However, to date, little is known about barriers and facilitators to coordination between these services in Switzerland. Furthermore, each canton in Switzerland follows their own informal guidelines on coordination in PC, contributing to discrepancies in coordinative approaches in PC services. The purpose of this study is therefore to investigate barriers and facilitators to coordination between PPC and SPC service providers in Switzerland. Moreover, the study explores the implications of this for patient outcomes. Problem centered interviews with 40 health care professionals in PPC and SPC across 4 cantons in Switzerland (Basel, Waadt, Luzerne, Ticino), as well as well as with 24 family care givers were carried out. Data from the interviews were analyzed and interpreted using qualitative content-analysis. Results indicated that perceived Barriers and facilitators to coordination include; education and training in PC, financial incentives for PC services, information transfer between PPC and SPC services and organization factors. Significantly, that the barriers have a perceived negative impact on quality of care service provisions in Switzerland. The results will inform 'best practices' with respect to the coordination of palliative care networks and propose different ways of achieving the goal of service integration in PC. This is relevant for informing supply planning in community-based palliative care.

Topic: Palliative Care and End-of-Life Issues
Subfield: Public Health, Environmental and Occupational Health
Field: Medicine
Domain: Health Sciences
The future of development of croatian viticulture and enology

The Republic of Croatia has eekstremely beneficial ecological conditions for grape and vine production.Different cultivars, long tradition, contemporary knowledge and tehnpology may reveal recognizable products of the highest quality, that is, the products that could fined their place on the fastidious world market.However, there are also many problems, like shortage of founds, old vineyards, shortage of equipment etc.It is necessary to stimulate foundation of vineyards on the most convenient sites, as well as the growth and development(of family farms with more than 90% of vineyards, to maintain tehnical and tehnological sectors of the big viticultural and enological firms.Also, to establish optimal tehnology in wine production from grapes to bottle filling, taking into consideration ecological and cultivar peculiarities.Heuce the importance of the expert advisory service and science, as well as new laws and regulations concordant with regulations of the other wine-growing countries of the EU, EEZ and the world proffesional organizations O.I.V. and C.I.D.E.A.O.

Topic: Wine Industry and Tourism
Subfield: Tourism, Leisure and Hospitality Management
Field: Business, Management and Accounting
Domain: Social Sciences
Tanggung Jawab Pendidikan Menurut Alquran

Education is the most important factor in shaping human resources superior. In order to realize quality education so many factors that are responsible for and actively involved in advancing education. The following description is trying to explain the responsibilities of education based on the approach to librarianship and through analysis of the interpretation of the Qur'anic verses relating to responsibility for education. Specifically verses that will be examined is the surah Luqman/31:12-19 and Surah at-Tahrim/66:6. The results of the analysis of the research indicates that real education responsibilities given to four groups, namely: 1) parents as the first educators, 2) Educators/teachers that provide formal science at educational institutions, 3) Learners as people who need guidance, and 4 facilitate the sustainability of the Government) of education

Topic: Education and Character Development
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Treatment of Pathological Tooth Migration using Non- Surgical Periodontal Therapy

Migration or drifting of teeth is always multifactorial. This is one of the major concerns in the field of dentistry. On long standing periodontal disease this pathological migratory phenomenon occurs. Treating this pathological tooth migration requires some of the modalities like periodontal therapy/ orthodontic therapy/ restorative therapy. But in some cases periodontal therapy alone plays an important role in spontaneous correction of PTM. Present case report also demonstrate the spontaneous correction of mandibular anterior tooth proclination and slight amount of open bite with non- surgical periodontal therapy (periodontal therapy) alone

Topic: Dental Trauma and Treatments
Subfield: Emergency Medical Services
Field: Health Professions
Domain: Health Sciences
Mortality Reduction Associated With β-Adrenoceptor Inhibition in Chronic Heart Failure Is Greater in Patients With Diabetes

OBJECTIVE Diabetes increases mortality in patients with chronic heart failure (CHF) and reduced left ventricular ejection fraction. Studies have questioned the safety of β-adrenoceptor blockers (β-blockers) in some patients with diabetes and reduced left ventricular ejection fraction. We examined whether β-blockers and ACE inhibitors (ACEIs) are associated with differential effects on mortality in CHF patients with and without diabetes. RESEARCH DESIGN AND METHODS We conducted a prospective cohort study of 1,797 patients with CHF recruited between 2006 and 2014, with mean follow-up of 4 years. β-Blocker dose was expressed as the equivalent dose of bisoprolol (mg/day) and ACEI dose as the equivalent dose of ramipril (mg/day). Cox regression analysis was used to examine the interaction between diabetes and drug dose on all-cause mortality. RESULTS Patients with diabetes were prescribed larger doses of β-blockers and ACEIs than were patients without diabetes. Increasing β-blocker dose was associated with lower mortality in patients with diabetes (8.9% per mg/day; 95% CI 5–12.6) and without diabetes (3.5% per mg/day; 95% CI 0.7–6.3), although the effect was larger in people with diabetes (interaction P = 0.027). Increasing ACEI dose was associated with lower mortality in patients with diabetes (5.9% per mg/day; 95% CI 2.5–9.2) and without diabetes (5.1% per mg/day; 95% CI 2.6–7.6), with similar effect size in these groups (interaction P = 0.76). CONCLUSIONS Increasing β-blocker dose is associated with a greater prognostic advantage in CHF patients with diabetes than in CHF patients without diabetes.

Topic: Heart Failure Treatment and Management
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Induced abnormal bone growth with particular reference to the growth plate

Limb deformities were successfully produced in skeletally immature lambs following contralateral limb hip excision arthroplasty. In order to determine the growth potential of the ovine skeleton prior to induced pelvic limb imbalance a preliminary study of normal epiphyseal fusion in comparable lambs has been performed. A detailed investigation of the angular bone deformities that were produced was then Undertaken. In particular, the growth cartilage of deformed bones was studied and both decalcified and undecalcified sections of bone extremities prepared. Undscalcified sections permitted microradiographs to be produced and as sequential bone labels were administered the effect on longitudinal bone growth of limb imbalance could be assessed. In addition, angiography was performed and differences were visualised in the blood supply adjacent to the growth plate following induced limb imbalance. Although pronounced angular deformities were produced, in addition, a dramatic increase in bone torsion was encountered in tibiae. In metatarsi there was normally minimal or no torsion in control animals but those undergoing deformity exhibited marked axial rotation. By means of static load bearing and gait analysis observations, the aetiology of induced bone deformities has been investigated. It is postulated that asymmetrical growth plate loading occurs and, as a result, abnormal endochondral bone growth is produced.

Topic: Orthopaedic implants and arthroplasty
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Congenital Diaphragmatic Hernia

In recent years, increasing numbers of patients with congenital diaphragmatic hernia (CDH) have been offered extracorporeal membrane oxygenation (ECMO) preoperatively if they can not physiologically tolerate early surgical repair. These infants are sicker and more unstable than those repaired pre-ECMO and, in most cases, have not had a "honeymoon" period (i.e., PaO 2 &gt;100 mm Hg at some point). ECMO before surgical repair was offered to 27 CDH patients in our institution; of the 16 (59%) survivors, 11 are now 2 years of age or older. To determine the outcome risk for this critical population, we compared 11 infants placed on ECMO pre-CDH repair (Group A) with our previous series of 22 survivors who had their surgery prior to ECMO (Group B). Both groups were similar in birth weight, gestational age, and Apgar scores. In Group A, a greater number were females (73% vs 23%), had right-sided hernia (64% vs 23%), and required patch repairs (82% vs 23%). The mean time on ECMO, time to extubation, and mean length of hospitalization were longer in group A. In both groups combined, the frequency of reherniation was higher in the patch-repair infants compared with those with a primary closure. Incidence of reflux was high in both groups, with increasing frequency of Nissen fundoplication in Group A patients (45% vs 6%). Both groups demonstrated similar delayed growth at 1 year of age. Although infants placed on ECMO presurgery are sicker, with more post-ECMO morbidity, their growth failure is similar to the less sick infants repaired pre-ECMO. Therefore, we recommend close followup of all CDH infants treated with ECMO in multidisciplinary follow-up clinics.

Topic: Congenital Diaphragmatic Hernia Studies
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
The role of screencasts in virtual accounting education

Despite the rapid growth of new technologies in universities, there is still little empirical evidence on the incidence of certain e-learnings mechanisms on students’ success or failure, particularly among accounting students. According to the cognitive theory of multimedia learning, screencasts are an effective and efficient tool for enhancing students learning, particularly in online accounting education where face-to-face interactions between instructor and students are limited.

Topic: Innovations in Educational Methods
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Early-Onset Severe Encephalopathy with Epilepsy: The BRAT1 Gene Should Be Added to the List of Causes

A variety of pathologies can underlie early-onset severe encephalopathy with epilepsy. To aid the diagnostic process in such patients we present an overview of causes, including the rapidly expanding list of genes involved. When no explanation is found, whole-exome sequencing (WES) can be used in an attempt to identify gene defects in patients suspected to suffer from a genetic form. We describe three siblings, born to consanguineous parents, with a lethal severe epileptic encephalopathy with early-infantile onset, including their magnetic resonance imaging, electroencephalography and, in one case, neuropathological findings. Using WES a homozygous frameshift mutation in the BRAT1 gene, c.638dup p.(Val214Glyfs*189), was identified. We present our cases in the context of all published cases with mutations in the BRAT1 gene and conclude that BRAT1 should be added to the growing list of genes related to early-onset severe encephalopathy with epilepsy.

Topic: Genomics and Rare Diseases
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences