jimnoneill/paper-to-field-training huggingface dataset:
Analisis Penerapan E-Korespondensi Pada PT X

This research was conducted at PT X which aims to find out the implementation, the impact of the implementation and the effectiveness of implementing e-Correspondence according to the views of employees at PT X. In this study the authors used a qualitative method with a case study approach. Data collection techniques used are interviews, observation and literature study. This data analysis technique includes data reduction, data presentation and drawing conclusions. The results obtained in this study are that the use of e-correspondence at PT X has not been implemented optimally, as evidenced by the presence of several obstacles that occur. Therefore, regular implementation must be optimized so that employees have a basis for carrying out effective correspondence activities.

Topic: Agriculture and Agroindustry Studies
Subfield: General Agricultural and Biological Sciences
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Study area (Image source: https://www.naturalearthdata.com/downloads/10m-cultural-vectors/).

&lt;p&gt;Study area (Image source: &lt;a href="https://www.naturalearthdata.com/downloads/10m-cultural-vectors/" target="_blank"&gt;https://www.naturalearthdata.com/downloads/10m-cultural-vectors/&lt;/a&gt;).&lt;/p&gt;

Topic: Peanut Plant Research Studies
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Plasma Endothelin in Normal and Diabetic Pregnancy

OBJECTIVE To examine endothelin-1 (ET-1) concentrations longitudinally throughout pregnancy in healthy and insulin-dependent diabetic women and to evaluate the relationship between ET-1 and big ET-1 in normal pregnancy. RESEARCH DESIGN AND METHODS Venous blood samples were obtained consecutively in gestational weeks 18, 28, and 38 from 40 healthy women with uneventful pregnancies and 24 pregnant women with IDDM. By radioimmunoassay, plasma ET-1 and big ET-1 were analyzed in the healthy women and plasma ET-1 in the diabetic women. RESULTS In the diabetic pregnant women, plasma ET-1 levels were significantly higher than in healthy pregnant women during the entire observation period (P &amp;lt; 0.001), but did not change with advancing gestational age. Five of the diabetic, but none of the healthy pregnant women, developed preeclampsia. ET-1 levels did not differ between the diabetic women who developed preeclampsia and those who did not. Plasma ET-1 levels in healthy pregnant women were within the range of those in healthy nonpregnant women and did not change during pregnancy. The big ET-1 levels increased and the ET-1/big ET-1 ratio decreased significantly during the observation period. CONCLUSIONS Plasma ET-1 levels do not change with advancing gestational length. During normal pregnancy, the ET-1/big ET-1 ratio decrease, indicating a suppressed converting enzyme activity or altered clearance of ET-1. Pregnant women with IDDM have markedly elevated ET-1 levels. Although diabetic women with and without preeclampsia did not differ with respect to endothelial dysfunction, as reflected by elevated ET-1 concentration, we cannot exclude that altered endothelial function may be of importance for the increased frequency of preeclampsia in pregnant IDDM patients.

Topic: Nitric Oxide and Endothelin Effects
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Thermodynamic Property of Quantum Bose Gas

This thesis deduced the statistical expression of thermodynamic quantity in Bose system with methods of quantum statistics,and obtained the internal energy,entropy and the intensity of pressure in Bose system,which are indicated by grand partition function.The expression of grand thermodynamic potential with the influence of outside or not is also discussed.And we also give the form of internal energy of Bose gas under weak degeneration.The thermal properties of photon gas are studied as a special case of Bose gas,and as results,we discussed Planck Formula and the expressions of internal energy,calorific,enthalpy,self energy and Gibbs function for photo gas.

Topic: Advanced Thermodynamics and Statistical Mechanics
Subfield: Statistical and Nonlinear Physics
Field: Physics and Astronomy
Domain: Physical Sciences
Split Calibration Curve: An Approach to Avoid Repeat Analysis of The Samples Exceeding Uloq

Using this method, repeat analysis of samples can be avoided. This is useful for the bioanalysis of toxicokinetic studies with wide dose ranges and studies where the sample volume is limited.

Topic: Biosimilars and Bioanalytical Methods
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Meet-in-the-Middle (Second) Preimage Attacks on Two Double- Branch Hash Functions RIPEMD and RIPEMD-128

Even though meet-in-the-middle preimage attack framework has been successfully applied to attack most of narrow-pipe hash functions, it seems difficult to apply this framework to attack double-branch hash functions. Only few results have been published on this research. This paper proposes a refined strategy of applying meet-in-the-middle attack framework to double-branch hash functions. The main novelty is a new local-collision approach named one-message-word local collision. We have applied our strategy to two double-branch hash functions RIPEMD and RIPEMD-128, and obtain the following results.• On RIPEMD. We find a pseudo-preimage attack on 47-step compression function, where the full version has 48 steps, with a complexity of 2119. It can be converted to a second preimage attack on 47-step hash function with a complexity of 2124.5. Moreover, we also improve previous preimage attacks on (intermediate) 35-step RIPEMD, and reduce the complexity from 2113 to 296.• On RIPEMD-128. We find a pseudo-preimage on (intermediate) 36-step compression function, where the full version has 64 steps, with a complexity of 2123. It canl be converted to a preimage attack on (intermediate) 36-step hash function with a complexity of 2126.5.Both RIPEMD and RIPEMD-128 produce 128-bit digests. Therefore our attacks are faster than the brute-force attack, which means that our attacks break the theoretical security bound of the above step-reduced variants of those two hash functions in the sense of (second) preimage resistance. The maximum number of the attacked steps on both those two hash functions is 35 among previous works based to our best knowledge. Therefore we have successfully increased the number of the attacked steps. We stress that our attacks does not break the security of full-version RIPEMD and RIPEMD-128. But the security mergin of RIPEMD becomes very narrow. On the other hand, RIPEMD-128 still has enough security margin.

Topic: Cryptographic Implementations and Security
Subfield: Artificial Intelligence
Field: Computer Science
Domain: Physical Sciences
Mapping metabolic oscillations during cell cycle progression

Proliferating cells must synthesize a wide variety of macromolecules while progressing through the cell cycle, but the coordination between cell cycle progression and cellular metabolism is still poorly understood. To identify metabolic processes that oscillate over the cell cycle, we performed comprehensive, non-targeted liquid chromatography-high resolution mass spectrometry (LC-HRMS) based metabolomics of HeLa cells isolated in the G<sub>1</sub> and SG<sub>2</sub>M cell cycle phases, capturing thousands of diverse metabolite ions. When accounting for increased total metabolite abundance due to cell growth throughout the cell cycle, 18% of the observed LC-HRMS peaks were at least twofold different between the stages, consistent with broad metabolic remodeling throughout the cell cycle. While most amino acids, phospholipids, and total ribonucleotides were constant across cell cycle phases, consistent with the view that total macromolecule synthesis does not vary across the cell cycle, certain metabolites were oscillating. For example, ribonucleotides were highly phosphorylated in SG<sub>2</sub>M, indicating an increase in energy charge, and several phosphatidylinositols were more abundant in G<sub>1</sub>, possibly indicating altered membrane lipid signaling. Within carbohydrate metabolism, pentose phosphates and methylglyoxal metabolites were associated with the cycle. Interestingly, hundreds of yet uncharacterized metabolites similarly oscillated between cell cycle phases, suggesting previously unknown metabolic activities that may be synchronized with cell cycle progression, providing an important resource for future studies.

Topic: Metabolism, Diabetes, and Cancer
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Early Support Service

The Early Support Service offers support, advice and coordination of needs to families where there is a child or children aged 0-8 years with additional needs or disabilities. The child’s needs would require input from at least 2 specialist services. The current Early Support Coordinator is a registered Health Visitor who works exclusively with families where children have additional needs.

Topic: Family and Disability Support Research
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Insulin resistance, HIV infection, and anti-HIV therapies.

Insulin resistance, a risk factor for cardiovascular disease, is increasingly seen in persons infected with HIV. In those affected, it is unclear whether insulin resistance is a direct result of HIV infection alone; however, the development of insulin resistance has been established as a complication of antiretroviral therapies. Some protease inhibitors (PIs) are culpable, and there are significant differences in the impact of different PIs on glucose metabolism, with current evidence suggesting that atazanavir does not cause insulin resistance. The paucity of standardized laboratory tests makes early diagnosis of insulin resistance relatively elusive. Still, there are some clinically useful methods for assessing its presence. For prevention and/or treatment, exercise and optimal diet are useful, and metformin and rosiglitazone have been shown to improve insulin resistance. Changing an effective antiretroviral regimen to counter insulin resistance must be approached thoughtfully in carefully selected patients.

Topic: HIV-related health complications and treatments
Subfield: Emergency Medicine
Field: Medicine
Domain: Health Sciences
1880-LB: Implementation of Artificial Intelligence (AI)–Based Diabetic Retinopathy Screening Improves Ophthalmology Follow-up in the Intermountain West

Introduction and Objective: AI-based retinal imaging is highly sensitive in detecting diabetic retinopathy (DR). However, follow-up adherence, referral efficiency, and ophthalmologist availability remain key challenges for disease monitoring and treatment access. This project examines the impact that AI-based DR screening has on ophthalmology follow-up rates within a three month time frame for patients with more-than-mild diabetic retinopathy (MTMDR), compared to traditional tele-retinal screening. Methods: Previously (2018-2021), point-of-care DR screening at the Utah Diabetes and Endocrinology Center at the University of Utah utilized a traditional tele-retinal protocol, where clinic-acquired images were transmitted for off-site interpretation by a retina specialist. The lag time from photo acquisition to patient notification of findings was 10 days on average. In May 2021, our clinic began using the AI-based DR screening program EyeArt, which provides immediate interpretation following photo-acquisition. A retrospective review of adults with T1D or T2D and MTMDR on screening compared the follow-up rates of traditional tele-retinal versus AI-based DR screening processes. Results: Among the 357 patients screened traditionally, 12% (n=42) had MTMDR, with 38% (n=16) completing in-person ophthalmology evaluation within three months. Since implementation of AI based screening in 2021, 584 patients have undergone screening, with 25% (n=144) found to have MTMDR, 51% (n=73) of whom completed in-person ophthalmology follow-up within three months. Conclusion: AI-based screening resulted in improved adherence to successful ophthalmology follow-up ophthalmology within three months following a positive screening test as compared to a traditional tele-retinal process. Immediate results and streamlined referrals likely contributed to improved follow-up adherence. However, significant barriers to ophthalmology engagement persist following a positive DR screening. Disclosure C. Watson: None. F.A. Aljabrain: None. M. Wahl: None.

Topic: Healthcare Systems and Public Health
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
The protective effects of S14G-humanin (HNG) against streptozotocin (STZ)-induced cardiac dysfunction

Excessive oxidative stress, inflammation, and myocardial hypertrophy have been associated with diabetic cardiomyopathy (DCM). S14G-humanin (HNG) is a potent humanin analogue that has demonstrated cytoprotective effects in a variety of cells and tissues. However, the pharmacological function of HNG in diabetic cardiomyopathy has not yet been reported. In the present study, we investigated the protective effects of HNG against streptozotocin (STZ)-induced cardiac dysfunction in diabetic mice. Myocardial hypertrophy in diabetic mice was determined using Wheat Gem Agglutinin (WGA) staining. The heart function was measured with Echocardiographic imaging. Levels of tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) proteins in plasma were measured using enzyme-linked immunosorbent assay (ELISA) kits. Protein expression of Phosphorylated p38/p38 was determined using western blots. We found that HNG treatment attenuated the STZ-induced myocardial hypertrophy and significantly improved heart function. Also, its treatment proved effective as it reduced the levels of several myocardial injury indicators, including creatine kinase-MB (CK-MB), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), and both the cardiac and plasma levels of TNF-α and IL-6, highlighting its effect on the STZ-induced myocardial injury. Lastly, HNG suppressed the activation of the p38/nuclear factor kappa-B (NF-κB) signaling pathway. S14G humanin possesses protective effects against streptozotocin-induced cardiac dysfunction through inhibiting the activation of the p38/NF-κB signaling pathway.

Topic: GDF15 and Related Biomarkers
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Equations of contact deformation for 2 spheres by indirect-fictitious boundary integral method (Modification of Hertz’s formula)

Ball bearings are used for many mechanisms. For the precious linear motion mechanism, it is very important to know the ball bearing deformation because the driving load is supported by the bearing. Especially, for the focus control mechanism of the optical telescope, even a very small deformation is not negligible because a sub-micron precision is required for the driving stroke. The Hertz’s formula is very familiar to the relation between the load and the displacement in a small contact area. Hertz derived the formula by using a potential of the electricity distribution in the ellipsoid body. However, it is reported that an error becomes large when the contact area is large. It is a reason that the elliptic paraboloid is used for the ellipsoid body in the Hertzian contact theory. Some modified equations are reported by Nishihara et.al, Tatara and Villaggio. However, the modified equations by Nishihara et al. and Villaggio are a little different from the FEM result. Therefore, in this paper, a contact deformation for the 2 equivalent spheres is analyzed by the indirect-fictitious boundary integral method. For the relation between the load and the displacement, a new modified equation with the fractional expression is derived in this paper. And, for the relation between the load and the contact radius, it is confirmed that the Hertz’s formula is correct.

Topic: Adhesion, Friction, and Surface Interactions
Subfield: Mechanics of Materials
Field: Engineering
Domain: Physical Sciences
Perspectives of Alienation in the Digital Labour Market. A Debate and Empirical Proposals between Philosophy, Sociology and Human Rights

The concept of alienation has long been central in philosophical and sociological thought, especially within critiques of industrial capitalism. With the advent of artificial intelligence and digital technologies, alienation has taken new forms in the digital labour market. This paper re-examines alienation through both theoretical and empirical lenses, drawing on Marxist, existentialist, and contemporary critical theories. We explore how algorithmic management, digital surveillance, and the fragmentation of work under digital capitalism contribute to feelings of powerlessness, detachment, and diminished autonomy. The study focuses on how these dynamics reshape human labour, not only in terms of productivity but also in the erosion of agency and recognition. Empirical evidence from education and the gig economy highlights the socio-psychological consequences of algorithmic control. We propose that alienation should be reconceived not merely as a private psychological response, but as a systemic, organizational, and collective phenomenon. Finally, the paper suggests alternatives such as ethical AI, cooperative work models, and legal safeguards to mitigate digital alienation. Through an interdisciplinary approach combining philosophy and sociology, the study aims to update the concept of alienation for the digital era and provide tools for understanding and transforming contemporary work.

Topic: Digital Economy and Work Transformation
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Influence of Artificial Diet on Larvae of Eri Silkworm, Samia cynthia ricini Boisduval

An Artificial Diet composed of castor leaf powder (11.5 g), parched soybean powder (1.0 g), sucrose (1.0 g), agar-agar (1.5 g), inhibitor solution (5 ml) and water (20 ml) was evaluated against eri silkworm larvae. Castor fed eri silkworms were maintained as control for comparison. Larval weight was significantly maximum in eri silkworms fed with artificial diet upto first instar which was followed by feeding of eri silkworms on artificial diet upto second instar + castor leaves from upto fifth instar and feeding of eri silkworm on artificial diet upto third instar + castor during remaining instars. Whereas, the larval mortality was minimum in eri silkworms reared on artificial diet upto first instar followed by artificial diet upto second and third instars + castor during remaining instars, whereas, they were higher in eri silkworms fed on artificial diet upto fourth and fifth instars + castor during remaining instars.

Topic: Silkworms and Sericulture Research
Subfield: Insect Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Stiffness influence atlases of a novel flexure hinge-based parallel mechanism with large workspace

Parallel-structure flexure mechanisms are increasingly designed due to their superior characteristics. This paper explores a novel six degree-of-freedom large workspace flexure parallel mechanism based on the concept of wide-range flexure hinge, which can attain sub-micron scale accuracy over cubic centimeter motion range. The geometric dimensions of the flexure hinges utilized in this mechanism as passive joints will influence the system stiffness directly and other properties indirectly such as the workspace, load-carrying capacity, and driving-load capacity etc. In this paper, the stiffness model of individual flexure hinge is established firstly, and then the stiffness of the whole flexure mechanism is modeled via assembling stiffness matrices and formulating constraint equations. Based on the system stiffness model of the whole mechanism, the stiffness atlases' analysis is presented which provides theoretical principles for designing and developing this kind of flexure parallel mechanism in further. Finally, a 6-PSS large workspace flexure parallel mechanism prototype is proposed according to the analysis results, which will be utilized in the precision positioning.

Topic: Robotic Mechanisms and Dynamics
Subfield: Control and Systems Engineering
Field: Engineering
Domain: Physical Sciences
Keeping Quality of Bottled Wines

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKeeping Quality of Bottled WinesC. S. Pederson, H. E. Goresline, A. L. Curl, and E. A. BeavensCite this: Ind. Eng. Chem. 1941, 33, 3, 304–307Publication Date (Print):March 1, 1941Publication History Published online1 May 2002Published inissue 1 March 1941https://pubs.acs.org/doi/10.1021/ie50375a006https://doi.org/10.1021/ie50375a006research-articleACS PublicationsRequest reuse permissionsArticle Views17Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts

Topic: Horticultural and Viticultural Research
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
BACTERIOLOGICAL QUALITY OF DRINKING WATER SOURCES IN RURAL COMMUNITIES OF DIRE DAWA ADMINISTRATIVE COUNCIL

In Ethiopia, access to improved water supply and sanitation was estimated at 38% and 12% respectively. Three- forth of the health problems of children in Ethiopia are communicable diseases due to polluted water and improper water handling practices. Thus, this study was conducted to assess the microbiological quality of drinking water sources in rural communities of Dire Dawa Administrative Council (Adada Peasant Association). A cross-sectional study was conducted from February 2011 to May 2011. Microbiological water quality parameters were analyzed using the membrane filtration method. Water analysis demonstrated that all water sources in the study area were contaminated with total coliforms and fecal coliform. The fact that, about 83.34% of the water sample was positive for indicator bacteria shown that the three selected Peasant Associations had risk of contamination. High concentration of microbiological indicators in all water sources of this study area have demonstrated the presence of pathogenic organisms which constitute a threat to anyone consuming or in contact with these waters. The majority of the drinking water sources is either of unacceptable quality or grossly polluted. Regular quality control mechanisms need to be in place to ensure safety of drinking water.

Topic: Child Nutrition and Water Access
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences