jimnoneill/paper-to-field-training huggingface dataset:
Non-Destructive Analytical Investigation of Decorative Wallpapers Samples of the Nineteenth Century before Their Restoration

In this work, decorative wallpapers (19th century) from an historical palace located in Oiartzun (Basque Country, Spain) were analyzed before their restoration. Micro-energy dispersive X-ray fluorescence spectroscopy, Raman spectroscopy, and attenuated total reflectance infrared spectroscopy were used to investigate the elemental and molecular composition of pigments, the presence of binders, and the state of conservation of the paper support. The aim of the investigation was trying to understand the possible degradation pathways and identify the raw materials in order to choose the best restoration protocol according to the original aspect of wallpapers. As stated from both the elemental distribution and the identification of mineral phases by Raman spectroscopy, the most used pigment was lead chromate. It was mixed with other pigments such as ultramarine blue, zinc chromate, hematite, and atacamite among others to obtain different shades and they were applied mixed with an animal glue. Brass, identified thanks to elemental micro-EDXRF maps, was employed as a shiny decorative element. In addition, a partial degradation of cellulose was detected due to its natural ageing, the acidic nature of lignin, and to a phenomenon of humidity of the walls. Probably the deposition of black particulate matter was the cause of the darkening of the painting surfaces.

Topic: Cultural Heritage Materials Analysis
Subfield: Archeology
Field: Arts and Humanities
Domain: Social Sciences
Determination of Fatty Acid Composition, Cholesterol and Fat-soluble Vitamin Levels of Capoeta trutta, Luciobarbus mystaceus and Luciobarbus esocinus Caught from the Keban Dam Lake, Elazig, Turkiye

The fatty acid composition, cholesterol and fat-soluble vitamin levels in the muscle tissue of economically important freshwater fish Luciobarbus esocinus, Capoeta trutta and Luciobarbus mystaceus were investigated. The analysis of fatty acid methyl esters was carried out by gas chromatography, and cholesterol and fat-soluble vitamin amounts were determined by high-performance liquid chromatography (HPLC). Among polyunsaturated fatty acids (PUFA), eicosapentaenoic acid (EPA, C20:5n-3) was found to be higher in C. trutta (14.84%) compared to the other fish species, while the highest amount of docosahexanoic acid (DHA, C22:6n-3) was determined in L. mystaceus (20.43%). While the maximum amount of total n-3/n-6 PUFA ratio was determined for C. trutta with 4.64%, it was determined that the sum of EPA and DHA from n-3 series fatty acids was higher in C. trutta with 31.74%. When the fat-soluble vitamin and cholesterol levels of the species were compared, it was found that the difference between the amounts of δ-tocopherol, α-tocopherol, D3, K1, K2 and cholesterol did not differ between the species. In conclusion, L. esocinus, C. trutta and L. mystaceus living in the Keban Dam Lake are valuable food source in terms of fatty acids, vitamin and cholesterol. It is thought that the findings of this study is beneficial for researchers and fish consumers.

Topic: Aquaculture Nutrition and Growth
Subfield: Aquatic Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Magnetic relaxation in pre-annealed amorphous (Fe<sub>0.1</sub>Ni<sub>0.35</sub>Co<sub>0.55</sub>)<sub>78</sub>Si<sub>8</sub>B<sub>14</sub>

The relaxations of structurally sensitive magnetic parameters, in particular those of magnetic permeability, were investigated on a pre-annealed nearly zero-magnetostrictive amorphous (Fe0.1Ni0.35Co0.55)78Si8B14 alloy at temperatures up to 300 degrees C. The ordinary disaccommodation (DA) and the continuous permeability decay in the total permeability relaxation exhibit a characteristic spectrum with a single relaxation peak. The distributions of the activation energies in the relaxation processes were evaluated. The most probable activation energies for DA and the decay are approximately 1.12 and 1.76 eV, respectively. It was confirmed that the permeability decay by aging is a process of reversible structural rearrangements. The crossover effect in the decay was observed and quantitative estimation made for the magnetic stability at lower temperatures.

Topic: Metallic Glasses and Amorphous Alloys
Subfield: Mechanical Engineering
Field: Engineering
Domain: Physical Sciences
A phase Ib dose escalation study of vantictumab (VAN) in combination with nab-paclitaxel (Nab-P) and gemcitabine (G) in patients with previously untreated stage IV pancreatic cancer.

249 Background: Vantictumab is a fully human monoclonal antibody that inhibits Wnt pathway signaling through binding FZD1, 2, 5, 7, and 8 receptors. A phase Ib study of VAN in combination with Nab-P and G was performed in patients with untreated stage IV pancreatic adenocarcinoma. Methods: Patients received VAN at escalating doses (3-7 mg/kg) in combination with standard dosing of Nab-P and G according to a 3+3 design. Due to fragility fractures occurring in this and other related clinical trials, dosing on an every 2 week schedule in cohorts 1 and 2 was transitioned to every 4 week dosing for cohorts 3 through 5. In these later cohorts, a minimum of six patients were treated at each dose level and additional criteria for maximum tolerated dose (MTD) integrating bone safety parameters were added. The bone safety plan was also revised for these cohorts. Sequential dosing of VAN followed by Nab-P and G was explored in cohort 5. Results: Thirty-one patients (52% male, 48% female) were enrolled and treated in 5 dosing cohorts. Median age was 66. Most common study-treatment related adverse events were nausea (68%) and fatigue (52%). One dose limiting toxicity (DLT) event occurred in the study population—grade 3 dehydration in 1 of 9 patients in cohort 4 (5 mg/kg q4w). Fragility fractures attributed to VAN occurred in two patients in cohort 2 (7 mg/kg q2w). Once the dosing schedule was revised to every 4 weeks, the maximum administered VAN dose was 5 mg/kg. No fragility fractures attributed to VAN occurred in these cohorts; pathologic fracture not attributed to VAN was documented in 2 patients. The study was terminated due to lack of an acceptable therapeutic index. Partial response was documented in 13 patients (42%) and stable disease in 11 (36%). Conclusions: The MTD of VAN plus Nab-P and G was not determined, but the maximum administered dose (MAD) of VAN, 7 mg/kg every 2 weeks, was considered unsafe related to bone toxicity, a known effect of WNT inhibition. After the study was revised, the MAD was 5 mg/kg every 4 weeks, with no protocol-specified bone toxicity observed (n = 16). Clinical trial information: NCT02005315.

Topic: Pancreatic and Hepatic Oncology Research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
The Relationship Between MOTS-c K14Q Polymorphism and Sarcopenia, Blood Lipids, and Mental Health in Older Korean Adults

Background/objectives: An East Asian-specific 1382A&gt;C polymorphism in the mitochondrial open reading frame of the 12S rRNA type-c results in an amino acid substitution from Lys (K) to Gln (Q) at the 14th amino acid residue. This study investigated the association between m.1382A&gt;C polymorphism and sarcopenia, blood lipids, and mental health in older Korean adults. Methods: The study included 683 community-dwelling Korean adults (345 men and 338 women) aged 65 years and older. The m.1382A&gt;C polymorphism was genotyped with a 7500 real-time PCR system. Handgrip strength (HGS) was measured, and appendicular skeletal muscle (ASM) mass was calculated. Demographics, blood lipids, falling risk, nutritional intake, cognition function, and depression were additionally measured. Results: Men carrying the C allele had significantly higher ASM (21.6 ± 3.0 vs. 19.5 ± 2.2 kg, p = 0.018), ASM/height2 (7.76 ± 0.76 vs. 7.14 ± 0.62 kg/m2, p = 0.012), lean mass (53.3 ± 6.2 vs. 46.5 ± 4.0 kg, p &lt; 0.001), left HGS (33.3 ± 5.0 vs. 28.9 ± 4.0 kg, p = 0.010), and right HGS (35.6 ± 5.3 vs. 30.9 ± 4.3 kg, p = 0.009) than men carrying the A allele. The genotype differences in ASM (p = 0.017), ASM/height2 (p = 0.011), lean mass (p &lt; 0.001), left HGS (p = 0.010), and right HGS (p = 0.009) remained significant even after adjusting for all measured covariates. By contrast, no significant differences in other measured parameters were found between women carrying the A and C alleles. Conclusions: Our study findings indicate that the m.1382A&gt;C polymorphism may be used as a genetic biomarker of age-related sarcopenia in older Korean men.

Topic: Nutrition and Health in Aging
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Restriction enzyme improves the efficiency of genetic transformations in Moniliophthora perniciosa, the causal agent of witches’ broom disease in Theobroma cacao

The presence of restriction enzymes in the transformation mixture improved the efficiency of transformation in Moniliophthora perniciosa. The influence of the vector shape (linear or circular), the patterns of plasmid integration in genomic sites and the influence of the promoter used to express the gene marker were also analyzed. The addition of BamHI or NotI increased the number of transformants by 3-10-fold and 3-fold, respectively, over the control without added enzyme. The use of pre-linearized plasmid did not increase the transformation efficiency in comparison with the circular plasmid. However, the frequency of multi-copy transformants increased significantly. The transformation procedure here reported resulted in better production of protoplasts and transformation efficiency. In addition, the time necessary for the detection of the first transformants and the number of insertions were reduced.

Topic: Cocoa and Sweet Potato Agronomy
Subfield: Horticulture
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Darstellung neuer substituierter 1,2,4‐Triazin‐6‐carbonsäuren und 1,2,4‐Triazin‐6‐yl‐alkancarbonsäuren

Synthesis of New Substituted as‐Triazine‐6‐carboxylic Acids and as‐Triazine‐6‐yl‐alkanoic Acids New substituted 3‐amino‐, 5‐amino‐ and 3,5‐diamino‐as‐triazine‐6‐carboxylic acids 4a , b , 5a , b and 6 were obtained by the hydrolysis 6‐azalumazine derivatives 3a – e . Corresponding acids of the structure 10a – d , 11a , b and 12 were synthesized from 5‐chlor‐3‐methylthio‐astriazine‐6‐carboxylic‐ester 8 . The synthesis of new 3‐alkylthioderivatives of as‐triazine‐6‐yl‐acetic acid 16a – c and ‐propionic acid 18 and its hydrolysis to 3,5‐dioxotetrahydro‐as‐triazine‐6‐yl‐propionic acid 19 is reported.

Topic: Synthesis and Characterization of Heterocyclic Compounds
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Low-dose Radiation Effects to Humans and the Importance of Eating Wisely

2011年3月11日の東日本大震災に端を発した福島第一原発事故の影響は,3年以上を経過した今なお12万人以上の方が県内外に避難を余儀なくされている。事故後3年半を経て,事故直後に騒がれた低線量放射線の子ども達への健康影響については,懸念されたような大きな影響はほとんどなかったとほっとする人がいる一方,長期的影響についてまだまだ不安を持っている人が多数いる事も事実である。そして,今なお福島で生きようとする方々の生活に放射線は大きくのしかかっている。既に昨年,本学会誌に「"低線量放射線を超えて"に込めたる想い」を寄稿したので,一部の重複はご容赦願うとして,日本原子力学会シンポジウム 女性のためのフォーラム「低線量放射線の生体への影響と食の重要性」でお話した内容および,この間思いがけず免疫を専門とする人間が,放射線・福島の問題に深く関わり考えたことについて,特に他の研究者があまり触れていない事を中心に,私自身の専門分野との関連から紹介する。

Topic: Radiation Dose and Imaging
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Competition over Competition Policy for International Trade and Intellectual Property

ABSTRACT Increasingly, international trade law demands that national competition policy play a role making domestic markets more accessible to foreign traders. But can international competition policy also control transnational business practices? New international intellectual property power is providing a reason why such control is needed. This article gauges the competition over the nature of competition policy in a global era.

Topic: Merger and Competition Analysis
Subfield: Economics and Econometrics
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Crystal phase induced band gap energy enhancing the photo-catalytic properties of Zn–Fe<sub>2</sub>O<sub>4</sub>/Au NPs: experimental and theoretical studies

Au NPs on ZnFe<sub>2</sub>O<sub>4</sub> enhances visible absorption, employed for paracetamol oxidation, where peaks were resolved by 2D HPLC.

Topic: Advanced Photocatalysis Techniques
Subfield: Renewable Energy, Sustainability and the Environment
Field: Energy
Domain: Physical Sciences
A biopsychosocial treatment approach to Post-Traumatic stress disorder

Post-Traumatic stress disorder (PTSD) is defined and treatment discussed from a combined biologic, psychologic, and social perspective. Literature relevant to each parameter is discussed. Pharmacologic interventions are described along with guidelines to carrying out the psychotherapeutic process which should accompany the former. Finally, insight is offered into the problems of the PTSD patient in using social support, with suggestions for their treatment.

Topic: Posttraumatic Stress Disorder Research
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Implementing Evidence-Based Instruction: Talking the Talk and Walking the Walk

No AccessPerspectives on Augmentative and Alternative CommunicationArticle1 Sep 2006Implementing Evidence-Based Instruction: Talking the Talk and Walking the Walk Joe Reichle Joe Reichle Department of Speech-Language-Hearing Sciences, University of MinnesotaMinneapolis, MN Google Scholar More articles by this author https://doi.org/10.1044/aac15.3.11 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationTrack Citations ShareFacebookTwitterLinked In References Bondy, A., & Frost, L. (1994). The picture exchange communication system.Focus on Autistic behavior, 9, 1–19. CrossrefGoogle Scholar Drasgow, E., Halle, J. W., & Ostrosky, M. M. (1998). Effects of differential reinforcement on the generalization of a replacement mand in three children with severe language delays.Journal of Applied Behavior Analysis, 31(3), 357–374. Google Scholar Justice, L. M., & Fey, M. E. (2004, Sept. 21, 2004). Evidence-based practice in schools: Integrating craft and theory with science and data.The ASHA Leader, 9, 4–5, 32. Google Scholar Mirenda, P. (2005). Toward functional communication in individuals with autism.Language Speech and Hearing Services in Schools, 34, 203–216. Google Scholar Reichle, J. (2001). Examining reliable practice in applied educational settings. Unpublished manuscript, University of Minnesota, MN. Google Scholar Reichle, J., Johnson, L.Hargrove, P., & Lund, B. (2006, November). Establishing technical assistance teams in schools: Challenging behavior and AAC. Paper submitted for a seminar to the ASHA annual Convention, Miami, FL. Google Scholar Schlosser, R. W., & Raghavendra, P. (2003). Towards evidence-based practice in augmentative and alternative communication. In R.W. Schlosser, The efficacy of augmentative and alternative communication: Towards evidence-based practice (pp. 259–297). New York: Academic Press. Google Scholar Shafer, E. (1993). Teaching topography-based and selection-based verbal behavior to developmentally disabled individuals: Some considerations.The Analysis of Verbal Behavior, 11, 117–133. Google Scholar Sundberg, M. (1993). Selecting a response form for nonverbal persons: Facilitated communication, pointing systems, or sign language?.The Analysis of Verbal Behavior, 11, 99–116. Google Scholar Additional Resources FiguresReferencesRelatedDetails Volume 15Issue 3September 2006Pages: 11-15 Get Permissions Add to your Mendeley library History Published in issue: Sep 1, 2006 Metrics Downloaded 19 times Topicsasha-topicsasha-article-typesasha-sigsCopyright & PermissionsCopyright © 2006 American Speech-Language-Hearing AssociationLoading ...

Topic: Behavioral and Psychological Studies
Subfield: Developmental and Educational Psychology
Field: Psychology
Domain: Social Sciences
A Roentgenographic Technique to Evaluate and Document Hindfoot Position

The position of the posterior portion of the foot is difficult to evaluate and document on the basis of clinical examination. Conventional roentgenographic techniques also do not allow objective determination of hindfoot position. A new roentgenographic technique utilizing a double-exposure has been developed to allow accurate documentation of the position of the calcaneus relative to the ankle. Normal adult values for this technique have been determined from 60 normal feet.

Topic: Foot and Ankle Surgery
Subfield: Orthopedics and Sports Medicine
Field: Medicine
Domain: Health Sciences
The Principle of Acupoint Selection Based on Branch and Root Treatment

Other SectionsAbstract서 론표치 측면에서 질병과 경혈의 관계본치 측면에서 변증을 통한 질병과 경혈의 관계표치와 본치의 측면에서 경혈 선혈의 원리결 론AcknowledgementFundingData availabilityConflicts of interestReference

Topic: Healthcare and Venom Research
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
SARS-CoV-2 vaccination in patients with inflammatory bowel disease: A systemic review and meta-analysis

Background: In the coronavirus disease 2019 (COVID-19) pandemic, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) vaccination has been effective in preventing COVID-19 infections and related mortality. The SARS-CoV-2 vaccination was also recommended by the international society for patients with inflammatory bowel disease (IBD). However, IBD patients were not recruited in prospective randomized clinical vaccine studies. To evaluate the efficacy and safety of SARS-CoV-2 vaccination in IBD patients, we conducted this systemic review and meta-analysis. Methods: We systematically searched PubMed, Medline, and the Cochrane Library for studies published between January 1, 2019, and September 9, 2021. Studies written in English reported the efficacy, seroconversion (anti–SARS-CoV-2 anti-spike (S) antibody titer beyond the threshold) rate, and adverse events after the SARS-CoV-2 vaccination in IBD patients. We extracted the author, date, study design, country, types of SARS-CoV-2 vaccination, number of IBD patients receiving SARS-CoV-2 vaccinations, and study outcomes. Published data from the enrolled studies were pooled to determine effect estimates. The study protocol was registered in PROSPERO (CRD42021264993). Results: We analyzed findings from 27 454 IBD patients who received SARS-CoV-2 vaccinations in 11 studies that met the inclusion criteria. The post–SARS-CoV-2 vaccination COVID-19 infection rate was comparable between the IBD patients and non-IBD patients (odds ratio [OR], 1.28 [95% CI, 0.96–1.71]) and higher in nonvaccinated IBD patients compared with vaccinated IBD patients (OR, 8.63 [95% CI, 5.44–13.37]). The adverse event rate, severe adverse events, and mortality after the SARS-CoV-2 vaccination were 69%, 3%, and 0%, respectively. Conclusion: The SARS-CoV-2 vaccine is effective and tolerated in preventing COVID-19 infections in IBD patients. Over 98% of patients had seroconversion after receiving all doses of the SARS-CoV-2 vaccination, and the influence of biologics on vaccination was limited. The SARS-CoV-2 vaccination is recommended for IBD patients.

Topic: SARS-CoV-2 and COVID-19 Research
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Doctors need to establish general skills before specialist training, says report

Doctors should establish more generalist skills before specialist training to cope with increasing rates of chronic disease, says a report by the Centre for Workforce Intelligence (CfWI).

The report, Informing medical and dental student intakes, is part of an ongoing project to review the future healthcare workforce, and it outlines the long term factors that are anticipated to affect future medical and dental school intakes. One of the factors cited most often was that of rising rates of …

Topic: Global Health Workforce Issues
Subfield: Emergency Medical Services
Field: Health Professions
Domain: Health Sciences
TINJAUAN YURIDIS TERHADAP VISUM ET REPERTUM SEBAGAI ALAT BUKTI DALAM PEMERIKSAAN

Visum et repertum is an equipment of valid evidence in court session and confessed in code/law and has permanent legal force, based on rule of section 186 KUHAP. The purpose of this paper is to explain and to give more detail about the visum et repertum which can be made as a means of valid evidence to determine death causes. The method used is bibliography study. The result shows that not only the visum et repertum as a means of evidence, but also the verification in the court will be believed by the confidence of judge for knowing that crime already happened as an effort in looking for the fact.

Topic: Legal Studies and Policies
Subfield: Law
Field: Social Sciences
Domain: Social Sciences
Dealing with death: The role of animal-themed literature in supporting children with grief and loss

Abstract The way that children deal with, and develop an understanding of death has long-term effects on their development and wellbeing. Mental health practitioners regularly turn to bibliotherapy (the use of books), many of which portray non-human animals as central characters, as a therapeutic tool for bereaved children. However, the extent to which non-human animal characters are used to assist children dealing with loss and dying, nor how and why it is used, particularly in relation to available therapies, is not well understood. To explore this, we conducted an online survey of 47 Australian mental health practitioners ( M = 45.55 years of age, SD = 12.81; 80.9% female) who specialise in providing grief counselling to children (average of 13.26 years +/− 10.05 of professional experience). Overall, just over half (60.0%, n = 24/40) of practitioners preferred to use animal-themed death literature. However, it was not the most frequently used, nor considered the most effective therapeutic option across all age groups. There was a clear reduction in perceived usefulness with age. Bibliotherapy with animal characters was considered most effective for children between the ages of 2 and 7, and least effective for those over 12. Thematic analyses of open-ended responses revealed three overarching themes: (1) Animal-themed bibliotherapy was viewed as helpful in creating a bridge to access children’s emotions and providing a safe space to share them. (2) Practitioners considered animal-characters helpful for developing accurate death conceptualisation in younger children due to their familiarity with animals. Familiarity helps to encourage children to apply their observations of animal life cycles to human death, children identify with animal-characters, and they generally find animals appealing. (3) Its adoption by a therapist is dependent on children’s unique characteristics, practitioners’ personal preferences and the availability of appropriate literature. Findings from this study provide insight into practitioner perceptions of the role animal-characters play in children’s understanding of death at different ages and help to inform subject-matter choice for bibliotherapy literature. Animal-themed death literature has application as an adjunct therapy tool to assist children experiencing grief related to death and dying, but also more broadly (e.g., teachers and caregivers) to foster a healthy understanding of death in children.

Topic: Human-Animal Interaction Studies
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences