jimnoneill/paper-to-field-training huggingface dataset:
Eyelid basal cell carcinoma

We read with interest the paper by Hamada et al ,1 which draws a number of conclusions from a 5 year follow up study of 69 periocular basal cell carcinomas (BCCs) treated by conventional surgery and, in particular, suggests that there is no place for Mohs micrographic surgery (MMS) in patients with periocular BCCs. MMS is the serial saucerisation excision with mapped horizontal tissue sections examining 100% of the surgical margins to produce histological evidence of tumour negative margins. Unfortunately, the data included in the paper are incomplete and if such conclusions are to be considered, then further clarification is required.

Risk of BCC recurrence relates directly to the nature of the tumours treated.2 The principal risk factors for recurrence include previous treatment, large tumour size, and an infiltrative or micronodular histological growth pattern. No information is given on the first two factors and the histological subtype was non-specified in approximately 45% of cases. We calculate from the data provided that the authors experienced a 19% 5 year recurrence rate in patients with a histologically infiltrative BCC.

If most of the “non-specified” tumours in Hamada’s series were small nodular tumours, as the paper implies, then Hamada’s series also differs significantly from other larger series in that it represents a group of patients with an inherently better prognosis. Other comments hint at this, in that 76% of BCCs were on the …

Topic: Nonmelanoma Skin Cancer Studies
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
ChemInform Abstract: Synthesis and Structure of New Layered Oxides, M<sup>II</sup>La<sub>2</sub>Ti<sub>3</sub>O<sub>10</sub> (M: Co, Cu, and Zn).

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Topic: Layered Double Hydroxides Synthesis and Applications
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Learning Dimensions

In this paper, we describe work to investigate the creation of engaging programming learning experiences. Background research informed the design of four fieldwork studies involving a range of age groups to explore how programming tasks could best be framed to motivate learners. Our empirical findings from these four studies, described here, contributed to the design of a set of programming "Learning Dimensions" (LDs). The LDs provide educators with insights to support key design decisions for the creation of engaging programming learning experiences. This paper describes the background to the identification of these LDs and how they could address the design and delivery of highly engaging programming learning tasks. A web application has been authored to support educators in the application of the LDs to their lesson design.

Topic: Teaching and Learning Programming
Subfield: Computer Science Applications
Field: Computer Science
Domain: Physical Sciences
Understanding The Impact of Mentorship, Marketing Skills, And Personality Traits on Career Readiness Of Gen Z Apprentices

This study explores the effects of mentorship, marketing skills, and personality traits on the career readiness of Generation Z interns in Indonesia. As organizations face rapid market evolutions, understanding how these factors influence early career success becomes essential. This research addresses the gap in quantitative evidence linking these variables with career outcomes in the Indonesian context. A quantitative survey was conducted among 19–34-year-old Gen Z interns across various industries, and data were analyzed using Partial Least Squares Structural Equation Modeling (PLS-SEM). The results indicate that mentorship, marketing skills, and personality traits significantly predict career readiness both individually and collectively. These findings suggest that educational institutions and business organizations should enhance their training programs to better prepare young professionals for the competitive job market, emphasizing the development of essential marketing skills and positive personality traits alongside robust mentorship. This study contributes to the literature by highlighting specific employability factors critical for Generation Z, offering insights into stakeholders involved in career development and talent management.

Topic: Grit, Self-Efficacy, and Motivation
Subfield: Social Psychology
Field: Psychology
Domain: Social Sciences
Influence of phallotoxins and metal ions on the rate of proteolysis of actin

The rate of proteolytic degradation of rabbit skeletal muscle actin by trypsin, alpha-chymotrypsin, and, mainly, subtilisin was followed by dual wavelength spectroscopy at 285 nm by reference at 320 nm. Phalloidin and phallacidin, two toxic bicyclic heptapeptides from the mushroom Amanita phalloides, protect F-actin against degradation by the proteolytic enzymes. G-actin, which does not combine with phalloidin when maintained in the monomeric state by working at low ionic strength, and bovine serum albumin, which also has no affinity to the toxin, are hydrolyzed at the same rates in the presence or absence of phalloidin. The proteolysis of F-actin is distinctly retarded by KCl alone, i.e., without phalloidin, whereas Mg2+ or Ca2+ as sole cations permit a rather high rate of hydrolysis. An even faster degradation of F-actin by subtilisin is observed in the presence of Mg2+ plus cytochalasin B. Adenosine diphosphate and triphosphate have no influence on the rate of the enzymatic degradation. The S sulfoxide of phalloidin, the nontoxic diastereomer of the toxic R form, exerts only a limited inhibitory effect on the enzymatic hydrolysis; secophalloidin, another nontoxic derivative, which does not bind to F-actin has practically no effect.

Topic: Cardiomyopathy and Myosin Studies
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
“Quasi Nonparametric” Upper Tolerance Limits for Occupational Exposure Evaluations

Upper tolerance limits (UTLs) are often used in comparing exposure data sets with an occupational exposure limit (OEL) or other regulatory criterion (RC): if the 95%-95% UTL does not exceed the OEL, one is 95% confident that at most 5% of exposures exceed the OEL, and the comparison "passes." The largest of 59 observations is a nonparametric (distribution-free) 95%-95% UTL (NPUTL); the chance that this largest value equals or exceeds the actual 95th percentile is at least 95%, regardless of the underlying data distribution. That many observations may seem excessive in clean environments or small studies, though, and one would like to "pass" using UTLs based on fewer observations sufficiently far below the OEL or RC. "Quasi-nonparametric" UTLs (QNP UTLs) accomplish this. QNP UTLs assign a "pass" so long as one has "59 [values] less than the RC" (the NPUTL itself), "30 less than 1/2 [of the RC]," "21 less than 1/3," and on down to "8 less than 1/10," the last matching a rule-of-thumb given in 2006 American Industrial Hygiene Association (AIHA) guidance. They are derived using the conservative, experience-based assumption that the data distribution is lognormal with log-scale standard deviation σ at most 2.0 (geometric standard deviation at most 7.39). Although based on this assumption, their statistical performance is reasonably unaffected or conservative when data come from other distributions often assumed for contaminant concentrations; moreover, their performance is insensitive to analytical variation. This conservative robustness merits the description "quasi-nonparametric." QNP UTLs are very easy to use. Reporting Limit (RL) issues do not arise. QNP UTLs reduce the numbers of observations needed to support conservative risk management decisions when sampling from compliant working conditions.

Topic: Occupational Health and Safety Research
Subfield: Radiological and Ultrasound Technology
Field: Health Professions
Domain: Health Sciences
Value of real-time gastric juice analysis in upper gastrointestinal endoscopy.

Real-time gastric juice analysis provided information about the presence of gastric lesions in an otherwise "normal" stomach at EGDS. It improved the diagnostic yield and optimized resource utilization without any additional effort by the endoscopist.

Topic: Helicobacter pylori-related gastroenterology studies
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Articulatory reflexes of the three-way contrast in labial stops and kinematic evidence for domain-initial strengthening in Korean

This study examines articulatory characteristics of the three-way contrast in labial stops / p p h p */ (lenis, aspirated, fortis, respectively) in Korean in phrase-initial and phrase-medial prosodic positions with a two-fold goal. First, it investigates supralaryngeal articulatory reflexes of the stops and explores articulatory invariance of these stops across prosodic positions. Second, it investigates Korean stops in kinematic terms from the perspective of domain-initial strengthening, and explores the nature of prosodically-conditioned speech production from a dynamical perspective. Results showed that the articulatory reflex of the three-way contrast was invariantly observed across prosodic positions with lip constriction degree (/ p /&lt;/ p h /&lt;/ p */), while lip constriction duration showed a binary distinction (/ p /&lt;/ p h p */). Kinematically, there was only very weak articulatory evidence for the contrast across prosodic positions: The V-to-C lip closing movement tended to be faster for / p h / than for / p /, and the C-to-V lip opening movement tended to be larger for / p h p */ than for / p /. As for domain-initial strengthening, the consonantal lip closing gesture was characterized by a larger, longer and slower articulation, whereas the vocalic lip opening gesture (after the release) was larger and faster, but not longer. Kinematic relations indicated that the lip closing movement is most likely controlled by a rate of the clock (possibly modulated by a temporal modulation gesture, or π-gesture) comparable to boundary effects in English, but the boundary-induced lip opening movement was better accounted for by a change in target (possibly modulated by a spatial modulation gesture, or μ-gesture) which was comparable to prominence rather than boundary effects in English. The cross-linguistic difference was interpreted as coming from different prosodic systems between Korean and English, presumably instantiated in dynamical terms of how the temporal and the spatial modulation gestures are phased with constriction gestures in relation to boundary marking versus prominence marking.

Topic: Phonetics and Phonology Research
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
A novel compound-heterozygous EPCAM mutation in congenital tufting enteropathy

1. Holt-Danborg L, Vodopiutz J, Nonboe AW, . SPINT2 (HAI-2) missense variants identified in congenital sodium diarrhea/tufting enteropathy affect the ability of HAI-2 to inhibit prostasin but not matriptase. Hum Mol Genet 2019; 28: 828-41. Google Scholar

Topic: Genetic factors in colorectal cancer
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
CCDC 683875: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
ERIC ED352478: Volunteer Venture '92. Proceedings of the Annual Statewide Conference on Volunteerism (Columbus, Ohio, May 27-29, 1992).

These conference proceedings contain abstracts of papers that were submitted for presentation and descriptions of all presentations and workshops from a conference on volunteerism. Three papers are included in full. Organized in five sections, the following are included: "Building Better Young People: Powerful and Practical Techniques to Teach Youth" (Brandywein); "Engaging Youth as Volunteers" (Beugen); "Peer Counseling Programs" (Clark); "Strengthening Adult-Youth Interactions"--complete paper (Groff); "Legal Issues in Youth Volunteerism" (Colley); "Cooperation and Competition: A Volunteer's Responsibility" (Maddy); "What's in It for YOUth?" (panel discussion); "Youth Leadership Skills" (Shelly); "The Role of the Community Relations Professional in Shaping the Corporate Social Vision" (Goldberg); "How to Develop an Employee Volunteer Program (Galligan); "Getting Media Coverage for Your Community" (panel discussion); "Preparing Employees for Community Leadership" (Jenkins); "Legal Ramifications of Employee Volunteer Program" (McCurley); "Gaining Management Support for Your Program" (Galligan); "Environmental Issues and Employee Involvement" (DeWein); "Involving Retirees and Labor Unions in Employee Volunteerism" (Hester, Breitenstein); "Special Events Spell Success" (Phillips); "How to Effectively Raise Money in the 90s" (Nichols); "Serving the Diverse Community" (Richards); "Technology for the 90s--How to Choose It" (Risch); "Organizational Values and Culture" (Shullman); "High Tech, Grass Roots Technology for the 90s--How to Use It"--complete paper (Souder);"Focus on the Future: Where Do We Want Volunteerism to Go" (Ellis); "Improving Your Listening Skills" (Savage); "Assessing Our Impact" (Ellis); "Managing the New Volunteer" (Cooper); "Influence Strategies" (Verble); "Legal Issues in Volunteerism" (Colley); "Volunteers: Guardians of Social Change"--complete paper (Lonergan); "Designing a Service Learning Program" (Beugen); "Volunteering Is for Everyone" (Bernstein); "The Interviewer as In-Depth Listener" (Savage); "Communicating Confidence" (Verble); "Staying on Purpose" (Braham); "Time Mastery" (White); "Creativity and Innovation: Zip!" (Schubert); "Effective Communication Skills" (Donadio); "The Legal Environment of Volunteer Referral Agencies" (McCurley); and "Managing Conflict with and among Young People" (Trichel). (KC)

Topic: Lung Cancer Treatments and Mutations
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Production and body composition traits of broilers in relation to breast weight evaluated by path analysis

Breast weight has great economic importance in poultry industry, and may be associated with other variables. This work aimed to estimate phenotypic correlations between performance (live body weight at 7 and 28 days, and at slaughter, and depth of the breast muscle measured by ultrasonography), carcass (eviscerated body weight and leg weight) and body composition (heart, liver and abdominal fat weight) traits in a broiler line, and quantify the direct and indirect influence of these traits on breast weight. Path analysis was used by expanding the matrix of partial correlation in coefficients which give the direct influence of one trait on another, regardless the effect of the other traits. The simultaneous maintenance of live body weight at slaughter and eviscerated body weight in the matrix of correlations might be harmful for statistical analysis involving systems of normal equations, like path analysis, due to the observed multicollinearity. The live body weight at slaughter and the depth of the breast muscle as measured by ultrasonography directly affected breast weight and were identified as the most responsible factors for the magnitude of the correlation coefficients obtained between the studied traits and breast weight. Individual pre-selection for these traits could favor an increased breast weight in the future reproducer candidates of this line if the broilers' environmental conditions and housing are maintained, since the live body weight at slaughter and the depth of breast muscle measured by ultrasonography were directly related to breast weight.

Topic: Animal Nutrition and Physiology
Subfield: Animal Science and Zoology
Field: Agricultural and Biological Sciences
Domain: Life Sciences
The Interconnectedness of Black Liberation: The Cross-Political Relationship of African and African American Leaders in the Struggle for Independence and the Civil Rights Movement (1950–60)

The linkages between African and African American freedom advocates began long before their demands actualized in the latter half of the 1950s and early 1960s. Some of the leaders of this global Black movement for self-determination met when they were students at historically Black colleges and universities (HBCUs) in the United States, notably, Lincoln University and Howard University. While these movements and their aims were generally connected, this article examines the close relationships of their political leaders. It was partly through their relationships that they were able to advance their political demands for freedom. The article explores the cross-political ties of African leaders Kwame Nkrumah and Nnamdi Azikiwe, and of African American leaders like W.E.B. Du Bois, in their respective movements for human rights recognition from 1950 to the early 1960s. This was a time in which legal segregation and racial violence targeted Black people in the United States and the presence of European colonialism encroached on the sovereignty of Africans. This article explores how these political relations and the events of these movements influenced one another. This research intends to help readers understand the interconnectedness of the global Black struggle for self-determination, specifically as it relates to African American Civil Rights leaders and the leaders of independence movements in Africa like Azikiwe and Nkrumah, who would become the first presidents of Nigeria and Ghana, respectively.

Topic: Race, History, and American Society
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Thermal reactions of cyclic ethers at high temperatures. III. Pyrolysis of furan behind reflected shocks

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThermal reactions of cyclic ethers at high temperatures. III. Pyrolysis of furan behind reflected shocksAssa Lifshitz, Menashe Bidani, and Shimon BidaniCite this: J. Phys. Chem. 1986, 90, 21, 5373–5377Publication Date (Print):October 1, 1986Publication History Published online1 May 2002Published inissue 1 October 1986https://pubs.acs.org/doi/10.1021/j100412a096https://doi.org/10.1021/j100412a096research-articleACS PublicationsRequest reuse permissionsArticle Views414Altmetric-Citations88LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts

Topic: Free Radicals and Antioxidants
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Professional Socialization and Development Needs of Coordinators of Clinical Education

Context Coordinators of clinical education (CCEs) play a vital role in ensuring effective clinical education experiences, including developing and maintaining clinical affiliation agreements, developing preceptors, evaluating students, preceptors, and clinical education sites, and managing conflict. However, CCEs are often not formally trained for the role. The purpose of this study was to understand the processes used to socialize CCEs and to identify professional development needs. Methods All 291 CCEs of accredited athletic training programs were purposively recruited through direct e-mails, and 132 CCEs participated in this cross-sectional online survey. The survey consisted of 4 sections: (1) demographics, (2) role induction (RI), (3) usefulness of RI (URI), and (4) socialization needs (SN). For RI, participants identified items that were included in the orientation into their roles (eg, overview of duties, resources provided). For URI, participants identified how useful each orientation tactic was. For SN, participants identified how helpful they would find topics if they were included in a formal CCE development workshop. A panel of experts established content validity of the survey, and it was piloted with 8 CCEs. Reliability was established via Cronbach α = 0.86. Results Common RI tactics were receiving contact information for current preceptors, overview of the duties as CCE, and review of clinical education documentation. All tactics included in RI were rated at least moderately useful . Topics that would be helpful as part of CCE training include assessing clinical skill development, analyzing clinical data, and navigating difficult conversations and conflict. Conclusion(s) Many tactics are used to socialize CCEs into their administrative roles, but orientations vary based on the institution. Providing CCEs clear direction could lead to better student outcomes and overall job satisfaction. Therefore, programs should develop detailed onboarding for their CCEs specific to their roles within the program and institution.

Topic: Athletic Training and Education
Subfield: Physical Therapy, Sports Therapy and Rehabilitation
Field: Health Professions
Domain: Health Sciences