jimnoneill/paper-to-field-training huggingface dataset:
Fan geographies and engagement between geopolitics of Brexit, Donald Trump, and Doctor Who on social media

The 2016 Brexit decision and Donald Trump's election to the US presidency that same year led to a wide variety of social media activity, ranging from visceral anger to unadulterated jubilation. How members of particular fandoms choose to express their emotions regarding a geopolitical event can be filtered through the lens of their fannish enthusiasm. Analysis of Doctor Who-influenced geopolitical engagement on Facebook that uses case studies of both Brexit and Donald Trump's election and 2017 inauguration shows that fans used Doctor Who to cope with emotionally taxing geopolitical events and expressed their anguish through the lens of selected Doctor Who plotlines. This use of social media permits fans to shape a new geopolitical landscape within which they can grapple with their political surroundings as influenced by their fandom.

Topic: Digital Games and Media
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Tilting Control of Railway Vehicle using Electric Actuators. 1st Report. Study on the Modeling and Feedforward Control using Stepping Motors.

In order to shorten the traveling time for passengers, it is more important to increase the speed on the curved sections than that on the straight secions of the railways. However, when the train passes along the curved section at high speed, it is uncomfortable for passengers because of the over centrifugal acceleration, when the effect of the cant of the rails cannot be suppressed. In this research, the experimental set-up "Over Centrifugal Acceleration Simulator" was developed, which simulated high-speed passing through curved sections indoors, and developed electric actuators for tilting using a stepping motor which is capable of accurate-positioning control without feedback control, instead of air cylinder or hydraulic actuator which is used by the pendulum car and the test car. By the experimental set-up, high-speed passing through curved sections was simulated and a control method for the electric tilting actuator was examined, i.e., feedforward control with the track data. Experiments were carried out under some conditions to verify the effectiveness of the control method of the tilting control with a stepping motor for good ride quality.

Topic: Railway Systems and Energy Efficiency
Subfield: Industrial and Manufacturing Engineering
Field: Engineering
Domain: Physical Sciences
Design and implementation of an electronic system to monitor and record agroclimatic variables in greenhouses

Objective: To describe the development of a low-cost electronic device that can monitor, track, record, store, export, and interpret climatic variables of greenhouse-produced crops. Methodology: An Arduino UNO board was used, along with specific sensors, to measure the agroclimatic variables under study. A Raspberry Pi® 3B+ board was also used to store and export the recorded information. The previously assembled device was installed in a greenhouse located in San Agustín Calvario, municipality of Cholula, Puebla, from March to July. Finally, graphs were developed to interpret the variables according to the agroclimatic requirements of native cucumber. Study Limitations/Implications: Greenhouses must have access to an electrical supply, regardless of their geographic location or the crop they produce. Findings: A low-cost electronic system and device were successfully developed, allowing each sensor to monitor, record, store, and export the following agroclimatic variables: minimum and maximum temperature, relative humidity, carbon dioxide (CO2) concentration, and light intensity in a greenhouse with electrical supply. Regarding data interpretation, graphs were developed for the agroclimatic variables in the greenhouse, based on the needs of the native cucumber plant.

Topic: Greenhouse Technology and Climate Control
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Curcumin combined with glycyrrhetinic acid inhibits the development of hepatocellular carcinoma cells by down-regulating the PTEN/PI3K/AKT signalling pathway.

Curcumin is an active component of turmeric, which is derived from the rhizomes of Curcuma longa. Glycyrrhetinic acid (GA) is a natural compound extracted from liquorice. Both curcumin and GA are widely used as anticancer agents for treating many human cancers. In this study, curcumin and GA were used separately and in combination to treat human hepatocellular carcinoma (HCC) HepG2 cells. MTT assays were used to evaluate cell proliferation. Flow cytometry was carried out to measure cell apoptosis and determine cell cycle progression. Western blot analyses were applied to determine the expression levels of B-cell lymphoma-2 (Bcl-2), B-cell associated X protein (Bax), phosphatase and tensin homolog (PTEN), phosphorylated phosphoinositide 3-kinase (PI3K) and AKT serine/threonine kinase 1 (Akt). The results showed that combined treatment with curcumin and GA resulted in a significant reduction in proliferation and an increase in apoptosis and G1 cell cycle arrest in HepG-2 cells. A xenograft tumour model showed that curcumin and GA suppressed HCC development in vivo. Moreover, by knocking down the expression of PTEN, we confirmed that curcumin and GA exert their anticancer effects by inhibiting the PTEN/PI3K/Akt signalling pathway. Collectively, these results indicate that the combination of curcumin and GA could effectively inhibit the development of HepG2 cells by inhibiting PTEN/PI3K/Akt signalling and could be a promising treatment strategy for patients with HCC.

Topic: Pharmacological Effects of Natural Compounds
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
[Paper] Still Images of High Spatial Resolution Enable Short TV Viewing Distances

Preferred viewing distance (PVD), which is the viewing distance favored in the home viewing environment, is important for overall TV broadcasting system assessments to guarantee the image quality of TV programs. Previous studies have suggested that image size and resolution have little effect on the PVD. However, in future TV systems such as ultra-high-definition TVs (UHDTVs), which are expected to have a wide field of view (FOV) and high spatial resolution, program production methods may change depending on the specific values of these parameters, and viewer behaviors may change accordingly. Here we used a program consisting of still images to show that viewer behavior differs between two spatial resolutions. This result suggests that the conditions in previous studies discouraged viewers from finding an optimized PVD for each scene because there was little need and insufficient time to move spontaneously.

Topic: Image and Video Quality Assessment
Subfield: Computer Vision and Pattern Recognition
Field: Computer Science
Domain: Physical Sciences
Sobre algunos problemas reales en visión por ordenador que conducen a sistemas de ecuaciones algebraicos

&lt;p&gt;[EN] In this paper we present some real problems which appear in computer vision which yields to nonlinear system of algebraic equations. We study the problem of camera calibration. Roughly speaking camera calibration consists in looking at the camera position in the 3- D world using as information the projection of a 3- D Scene in a 2-D plane (the photogram). The problem is quite different when we use a single view or several views (stereo vision) of the 3-D scene. We will show in this paper how these problems yields to nonlinear algebraic system of equations.&lt;/p&gt;

Topic: Magnetic confinement fusion research
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
A Comparative Study of the Characteristics, Actions, and Mythological Symbols of the God Mithra in Religious and Mythological Narratives and Ancient Iranian Stories, and its Manifestation in the Sasanian Relief of Taq-e Bostan, Kermanshah

The god Mithra and Jamshid Pishdadi are among the oldest mythological and religious figures of the Aryan people, playing a role in the beliefs of the Aryans before their migration and before the emergence of Zoroaster. With the appearance of Zoroaster, and the development of his thoughts in the Gathas, there is a pronounced opposition to Jamshid’s teachings, which prominently feature the sacrifice of the bull and the consumption of the intoxicating Haoma. These two practices are the main characteristics of Mithraic religion within Aryan mythology. The similarity between Jamshid and Mithra is so significant that it prompts the researcher to question whether Mithra and Jamshid can be seen as one symbolic figure within Aryan mythological and religious narratives. How have Mithraic symbols, as represented in ancient Iranian myths and narratives, been reflected in the motifs and symbols of Taq-e Bostan? This article seeks to prove the unity of Mithra and Jamshid as one figure and to uncover the relationship between the Mithraic and Zoroastrian discourses in shaping these two myths and their impact on the formation of the Aryan creation myth. Using an analytical and descriptive approach, it examines the god Mithra and Jamshid Pishdadi within the framework of religious and mythological beliefs, comparing and analyzing them. Based on this approach, Mithra manifests in Jamshid’s character in three forms, each illustrating a unique function in the Aryan mythological world. The first manifestation of Mithra is as the deity who sacrifices the bull, marking the beginning of Ahuric creation. The second is represented in Jamshid’s luminous, radiant form, protecting the Ahuric world from Ahriman’s harm. The third phase, during the Ahuric resurrection, presents the god Mithra as Saoshyant, bringing immortality with Jamshid’s primary teaching, which is the sacrificial act of the bull.

Topic: Eurasian Exchange Networks
Subfield: Anthropology
Field: Social Sciences
Domain: Social Sciences
Avoidance and intolerance of uncertainty: Precipitants of rumination and depression

The primary goal of the present study was to examine whether avoidance and intolerance of uncertainty predict depression and anxiety through rumination over a two week time period. Results indicated that cognitive, behavioral, and experiential avoidance all individually predicted depressive and anxious symptoms over two weeks. Cognitive, behavioral, and experiential avoidance all predicted rumination one week later. Intolerance of uncertainty predicted higher levels of anxiety and depression but not rumination. No evidence emerged that rumination acted as a mechanism of action between any of the hypothesized mediational models for depressive symptoms. Only the cognitive and experiential avoidance mediational models indicated mediation for anxiety.

Topic: Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
Roe v Wade Was Followed by a Decrease in Neonatal Homicide

<h3>To the Editor.</h3> —The decision by the US Supreme Court in 1973 in<i>Roe v Wade</i>(410 US 113) made it far easier for women in America to obtain abortions. Therefore, the number of unwanted children born to American women might have been expected to decrease. This in turn might have resulted in lower rates of infant abuse and, in the extreme, homicide of newborns. It is impossible to obtain accurate estimates of the incidence of infant or child abuse in America, but neonatal homicide is accurately recorded. To explore whether this legal decision was associated with a reduction in neonatal homicide, the homicide rates by age were examined for each year in the periods from 1963 through 1972 and from 1974 through 1983 using data from<i>Vital Statistics of the United States</i>, which is published by the National Center for Health Statistics. (It should be noted that in 1980,

Topic: Homicide, Infanticide, and Child Abuse
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Etiology, Epidemiology, Patho physiology and Histo pathology of Idiopathic Pulmonary Fibrosis

The progressive lung condition known as idiopathic pulmonary fibrosis (IPF) is characterised by lung scarring, especially from an unidentified source. The long-term prognosis for the disorder is dismal. IPF's classic symptoms include increasing dyspnoea, a dry, ineffective cough, and a slow development of shortness of breath. Restricted lung function impairment, decreased functional vital capacity, and decreased carbon monoxide diffusing capacity are typically linked to pulmonary function testing. Due to the disease's propensity to develop quickly in its later stages, early identification is crucial for optimal care. With a thorough evaluation of the patient's medical history, imaging findings, and elimination of other illnesses, the diagnosis may often be made without a biopsy. Whatever it is, when there is ambiguity about the diagnosis, a lung biopsy can be necessary. In order to help diagnose IPF, imaging methods particularly computed tomography scans often show a characteristic pattern of fibrosis, which is usually shown along the edges of both lungs and more concentrated at the bases in a timely way. In situations when the diagnosis is unclear, a lung biopsy can help determine the diagnosis. Treatment options include supportive care, oxygen supplementation when necessary, antifibrotic drugs, and, in extreme situations, lung transplantation, which is the only cure. In addition to emphasising the importance of the interprofessional healthcare team in its evaluation, diagnosis, and management, this exercise provides a thorough explanation of the aetiology, epidemiology, clinical symptoms, diagnosis, and therapy of IPF in adults.

Topic: Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Supplementary Table 2 from Aberrant Expression of proPTPRN2 in Cancer Cells Confers Resistance to Apoptosis

&lt;p&gt;Immunohistochemical expression of proPTPRN2 in invasive breast carcinoma specimens in National Cancer Institute Progression tumor microarrays.&lt;/p&gt;

Topic: RNA modifications and cancer
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
[Liddle's syndrome caused by a novel mutation of the gamma-subunit of epithelial sodium channel gene SCNN1G in Chinese].

Screening for specific mutations of the SCNN1 gene in relatives of patients with Liddle's syndrome can be used to identify the previously unrecognized cases within the family. A new nonsense mutation(Q567X) of the SCNN1G gene is likely the cause of Liddle's syndrome in family 2.

Topic: Ion Transport and Channel Regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Supplemental Figure S1 from Targeting RRM2 and Mutant BRAF Is a Novel Combinatorial Strategy for Melanoma

&lt;p&gt;Figure S1. Combinatorial inhibition of RRM2 and mutant BRAF inhibits cell proliferation to a greater extent than either treatment alone.&lt;/p&gt;

Topic: Melanoma and MAPK Pathways
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Quo Vadis the fumigants?

Fumigation is the most widely used procedure to control stored product pests to prevent economic and quality losses by providing various application methods and penetration capability into the treated commodity. However, most of the available fumigants have limitations in use due to various reasons. Methyl bromide (MB), according to Montreal Protocol, is scheduled to be phased out worldwide by 2015. Sulphuryl fluoride (SF) is known to have limited efficiency on egg stages of insects. Reportedly, it also contributes to the greenhouse effects, which may jeopardize its future use. Currently, phosphine (PH 3 ) is the most widely used fumigant worldwide due to its low cost and ease of application, though resistance observed in major pest species threatens the continued use of PH 3 . Recent studies in beetles reveal that phosphine resistance is governed through two genes on separate autosomal chromosomes. Research on new fumigants continue to be restricted due to concerns over the adverse effects of fumigant residues in food and the environment that led regulatory agencies to take actions by imposing strict limitations on fumigant registration. On the other hand the phase out of MB and resistance to PH 3 has stimulated significant interest on development of alternatives like modified atmospheres (MAs), thermal disinfestation and irradiation. In Turkey, MAs applications are preferred for the treatment of organic food products and are performed mostly in transportable PVC structures (Cocoons or Volcani Cubes). In museums high nitrogen or SF applications are the only procedures to eradicate structural pests. Under the given constraints of registration of new fumigants, it is anticipated that more attention will be devoted to develop novel alternative treatments that are economically feasible, sustainable, user friendly and environmentally benign. Keywords : Fumigants, Modified atmospheres, Insect resistance, Stored products pests, Fumigant alternatives

Topic: Insect Pest Control Strategies
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Trade Openness, FDI and Economic Growth: Evidence from SAARC Countries

<strong>Abstract: </strong>This study attempts to empirically examine the role of international trade and FDI inflows in the economic development of South Asian Association for Regional Cooperation (SAARC) countries and to analyze impact on economic growth. The panel analysis using random effect model shows that there is a significant impact of trade on the development of the SAARC group of countries for the period 1993-2019. The capital flows measured in terms of FDI net flows also shows a positive impact on the growth rate of GDP. <strong>Keywords</strong>: Trade Openness, Economic Growth, Random Effects <strong>JEL Classification Number</strong>: F14, 040

Topic: Global trade and economics
Subfield: General Economics, Econometrics and Finance
Field: Economics, Econometrics and Finance
Domain: Social Sciences
CAN WE BE BRIEF?

abstract The author explores the subjective and objective nature of time in relation to brief psychotherapy, the contemporary contexts for this work and the impact of research on the changing culture of provision of counselling/psychotherapy. She describes clinical treatment using a brief Dynamic Relational approach with a traumatized patient in primary care who presents with panic and depression. Through this case she illustrates the most significant points of technique in her interpretation of this approach: assessment through interactional aspects of the first and second meetings, further assessment through history‐taking and the development of narrative, forming a collaborative focus based on a maladaptive relational pattern, selective inattention and benign neglect, interpretative ‘action’, termination and the collaborative therapeutic summary and use of other attachment figures available in the primary care team setting, particularly during the termination phase. The patient's unconscious and conscious internalization processes enable brief treatment to be durable, and it is argued that depth can be achieved. The author contends that brief therapy requires specific techniques but also makes connections with long‐term analytic work, for example, the parallel between Bion's concept of the ‘selected fact’ and the ‘focus’ in brief therapy.

Topic: Psychotherapy Techniques and Applications
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Assessment of Additively Manufactured Thermoplastic Composites for Ablative Thermal Protection Systems (TPSs)

This study focused on the thermal stability and ablative behavior assessment of five newly developed composite TPS configurations. All ten test samples were 3D printed via FDM using various fire-retardant thermoplastic materials, with and without reinforcement. Eight samples integrated a new thermal management internal air chamber conceptualized architecture. A prompt feasible approach for the flame resistance preliminary assessment of ablative TPS samples was developed, using an in-house oxy-acetylene torch test bench. Experimental OTB ablation tests involved exposing the front surface samples to direct flame at 1450 ± 50 °C at 100 mm distance. For each configuration, two samples were tested: one subjected to 30 s of flame exposure and the other to 60 s. During testing, internal temperatures were measured at two backside sample contact points. Recorded temperatures remained below 46 °C, significantly under the maximum allowable back face temperature of 180 °C set for TPSs. The highest mass losses were measured for PC and PETG FR materials, achieving around 19% (30 s) and, respectively, 36% (60 s), while the reinforced configurations showed overall only a third of this reduction. The study’s major outcomes were the internal air chamber concept validation and identifying two reinforced configurations as strong candidates for the further development of 3D-printed ablative TPSs.

Topic: Additive Manufacturing and 3D Printing Technologies
Subfield: Automotive Engineering
Field: Engineering
Domain: Physical Sciences
Oleanane- and Ursane-Type Triterpene Saponins from <i>Centella asiatica</i> Exhibit Neuroprotective Effects

Six new pentacyclic triterpenoid saponins, centelloside F (<b>1</b>), centelloside G (<b>2</b>), 11-<i>oxo</i>-asiaticoside B (<b>3</b>), 11-<i>oxo</i>-madecassoside (<b>4</b>), 11(β)-methoxy asiaticoside B (<b>5</b>), and 11(β)-methoxy madecassoside (<b>6</b>), along with seven known ones, asiaticoside (<b>7</b>), asiaticoside B (<b>8</b>), madecassoside (<b>9</b>), centellasaponin A (<b>10</b>), isoasiaticoside (<b>11</b>), scheffoleoside A (<b>12</b>), and centelloside E (<b>13</b>), were separated from the 80% MeOH extract of the whole plant of <i>Centella asiatica</i>, which has been used as a medicinal plant and is now commercially available as a diatery supplement in many countries. Compounds <b>1</b> and <b>2</b>, <b>3</b> and <b>4</b>, and <b>5</b> and <b>6</b> are three pairs of isomers with oleanane- or ursane-type triterpenes as aglycones. The chemical structures of the new triterpene saponins were fully characterized by extensive analysis of their nuclear magnetic resonance and high-resolution electrospray ionization mass spectrometry data. The protective effects of compounds <b>1</b>-<b>13</b> on PC12 cells induced by 6-OHDA were screened, and compound <b>3</b> displayed the best neuroprotective effect, with 91.75% cell viability at the concentration of 100 μM. Moreover, compound <b>3</b> also attenuated cell apoptosis and increased the mRNA expression of antioxidant enzymes, including superoxide dismutase and catalase. Additionally, compound <b>3</b> activated the phosphatidylinositol 3-kinase/Akt pathway, including PDK1, Akt, and GSK-3β. These findings suggested that triterpene saponins from <i>C. asiatica</i> were worthy of further biological research to develop new neuroprotective agents.

Topic: Medicinal Plants and Neuroprotection
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences