jimnoneill/paper-to-field-training huggingface dataset:
Image_6_Identifying α-KG-dependent prognostic signature for lower-grade glioma based on transcriptome profiles.tif

&lt;p&gt;The inhibition of alpha-ketoglutarate (α-KG)-dependent dioxygenases is thought to contribute to isocitrate dehydrogenase (IDH) mutation-derived malignancy. Herein, we aim to thoroughly investigate the expression pattern and prognostic significance of genes encoding α-KG-dependent enzymes for lower-grade glioma (LGG) patients. In this retrospective study, a total of 775 LGG patients were enrolled. The generalized linear model, least absolute shrinkage and selection operator Cox regression, and nomogram were applied to identify the enzyme-based signature. With the use of gene set enrichment analysis and Gene Ontology, the probable molecular abnormalities underlying high-risk patients were investigated. By comprehensively analyzing mRNA data, we observed that 41 genes were differentially expressed between IDH&lt;sup&gt;MUT&lt;/sup&gt; and IDH&lt;sup&gt;WT&lt;/sup&gt; LGG patients. A risk signature comprising 10 genes, which could divide samples into high- and low-risk groups of distinct prognoses, was developed and independently validated. This enzyme-based signature was indicative of a more malignant phenotype. The nomogram model incorporating the risk signature, molecular biomarkers, and clinicopathological parameters proved the incremental utility of the α-KG-dependent signature by achieving a more accurate prediction impact. Our study demonstrates that the α-KG-dependent enzyme-encoding genes were differentially expressed in relation to the IDH phenotype and may serve as a promising indicator for clinical outcomes of LGG patients.&lt;/p&gt;

Topic: Microbial Natural Products and Biosynthesis
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Finite element approximation of coupled seismic and electromagnetic waves in fluid‐saturated poroviscoelastic media

Abstract This work presents a collection of global and iterative finite element procedures for the numerical approximation of coupled seismic and electromagnetic waves in 2D bounded fluid‐saturated porous media, with absorbing boundary conditions at the artificial boundaries. The equations being analyzed are the coupled Biot's equations of motion and Maxwell equations in the diffusive range. Both seismoelectric and electroseismic coupling are simultaneously included and analyzed in the model. The case of compressional and vertically polarized shear waves coupled with the transverse magnetic polarization (PSVTM‐mode) is analyzed in detail, including the derivation of a priori error estimates on the global finite element procedure and results on the convergence of a domain decomposition iterative algorithm. Later, the corresponding results for the case of horizontally polarized shear waves coupled with the transverse electric polarization (SHTE‐mode) are stated. © 2009 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq, 2011

Topic: Numerical methods in engineering
Subfield: Mechanics of Materials
Field: Engineering
Domain: Physical Sciences
Taurine: A Source and Application for the Relief of Visual Fatigue

According to reports, supplementation with appropriate doses of taurine may help to reduce visual fatigue. Presently, some progress has been made in research related to taurine in eye health, but the lack of systematic summaries has led to the neglect of its application in the relief of visual fatigue. This paper, therefore, provides a systematic review of the sources of taurine, including the endogenous metabolic and exogenous dietary pathways, as well as a detailed review of the distribution and production of exogenous taurine. The physiological mechanisms underlying the production of visual fatigue are summarized and the research progress of taurine in relieving visual fatigue is reviewed, including the safety of consumption and the mechanism of action in relieving visual fatigue, in order to provide some reference basis and inspiration for the development and application of taurine in functional foods for relieving visual fatigue.

Topic: Aldose Reductase and Taurine
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Lateral root initiation requires the sequential induction of transcription factors LBD16 and PUCHI in <i>Arabidopsis thaliana</i>

Summary Lateral root (LR) formation in Arabidopsis thaliana is initiated by asymmetric division of founder cells, followed by coordinated cell proliferation and differentiation for patterning new primordia. The sequential developmental processes of LR formation are triggered by a localized auxin response. LATERAL ORGAN BOUNDARIES‐DOMAIN 16 (LBD16), an auxin‐inducible transcription factor, is one of the key regulators linking auxin response in LR founder cells to LR initiation. We identified key genes for LR formation that are activated by LBD16 in an auxin‐dependent manner. LBD16 targets identified include the transcription factor gene PUCHI , which is required for LR primordium patterning. We demonstrate that LBD16 activity is required for the auxin‐inducible expression of PUCHI . We show that PUCHI expression is initiated after the first round of asymmetric cell division of LR founder cells and that premature induction of PUCHI during the preinitiation phase disrupts LR primordium formation. Our results indicate that LR initiation requires the sequential induction of transcription factors LBD16 and PUCHI.

Topic: Plant Molecular Biology Research
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
El aprovechamiento económico de los bienes de uso público. Reflexiones con ocasión del reciente fallo de unificación sobre la improcedencia del contrato de arrendamiento

In the Colombian legal system, rules pertaining to private occupation of public property available for public use, including its economic exploitation, are uncertain. In the absence of legal clarity, the Council of State has ruled to exclude the possibility to use a lease contract to grant private occupation of public property available for public use. Although a reasonable decision, such ruling is poorly justified by the Colombian administrative judge. This paper vindicates a new contractual model for managing public property available for public use that takes into account the peculiarities of its legal regime and protection, as well as the need of an economic and social use.

Topic: Magnetic confinement fusion research
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
CAoSLEFGMVFpcE01RlJOYVU2aDVQR2tpeWtPTXNoN0Q4bkowanZhQ3UtTTlQcENa-240

Source: GoogleStreetViewStatic 4DCity URL: https://4dcity.org/imgupload/1653147437.595.jpg Original Image URL: https://maps.googleapis.com/maps/api/streetview?pano=CAoSLEFGMVFpcE01RlJOYVU2aDVQR2tpeWtPTXNoN0Q4bkowanZhQ3UtTTlQcENa&heading=240&fov=120&size=1200x1200&key=AIzaSyBjhzVSplTwzFdSsgSFCLpVrd3Wkdmx_GA Image-Metadata:Filename: 1653147437.595.jpgImage Dimensions: 640x640Megapixels: 0.41 MPFilesize: 60.34 KB

Topic: Insect and Pesticide Research
Subfield: Insect Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Clinical Observation of Meniere's Disease

我々の経験した55例のメニエール病症例につき, その年令分布・聴力型・聴力損失等を検討した. その結果, これらの項目については, 諸家の報告とほぼ同様の傾向を示した.また, 新鮮例で経過観察の十分行なえた24例について, 保存的治療とめまいおよび聴力の経過を検討した. めまいについては, 95.8%の改善がみられたが, めまいの完全消失例はなかった. 聴力は, 62.5%が不変・33.3%が悪化を示した.さらに, 3例の症例をあげ, 保存的治療とめまい・聴力の経過を示すとともに, 聴力の変動について, 保存的治療および手術治療に関する文献的考察を加えた.以上の結果より, めまいの完全治癒・聴力の保存のために, よりよい治療法の確立が望まれることを強調した.

Topic: Vestibular and auditory disorders
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Determinant of the Efficiency of Islamic Commercial Banks in Indonesia

This study aims to analyze what variables affect the efficiency of Islamic Commercial Banks in Indonesia. Design/methodology/approach: This study uses secondary data involving 9 Islamic Commercial Banks that report quarterly financial statements in full to the Otoritas Jasa Keuangan. The period used is during the first to fourth quarters of 2016 – the first to fourth quarters of 2021. This study uses Data Envelopment Analysis with the help of DEAP software version 2.1 and Tobit Regression Analysis with the help of STATA software version 14.2. Findings: The results of this study indicate that the variables of Third Party Funds, ROA and ROE have no positive and insignificant effect on the efficiency value. Meanwhile the variables FDR and Operating Cost of Operating Income have no negative and insignificant effect on the efficiency value. Variables CAR and Operating Expenses Operating Income have positive and significant effect on the value of efficiency. However, the variables of Bank Size and NPF have negatif and significant effect on the efficiency value.

Topic: Islamic Finance and Banking Studies
Subfield: Accounting
Field: Business, Management and Accounting
Domain: Social Sciences
CCDC 1047536: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: X-ray Diffraction in Crystallography
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Event Oriented Dictionary Learning for Complex Event Detection

Complex event detection is a retrieval task with the goal of finding videos of a particular event in a large-scale unconstrained Internet video archive, given example videos and text descriptions. Nowadays, different multimodal fusion schemes of low-level and high-level features are extensively investigated and evaluated for the complex event detection task. However, how to effectively select the high-level semantic meaningful concepts from a large pool to assist complex event detection is rarely studied in the literature. In this paper, we propose a novel strategy to automatically select semantic meaningful concepts for the event detection task based on both the events-kit text descriptions and the concepts high-level feature descriptions. Moreover, we introduce a novel event oriented dictionary representation based on the selected semantic concepts. Toward this goal, we leverage training images (frames) of selected concepts from the semantic indexing dataset with a pool of 346 concepts, into a novel supervised multitask lp -norm dictionary learning framework. Extensive experimental results on TRECVID multimedia event detection dataset demonstrate the efficacy of our proposed method.

Topic: Human Pose and Action Recognition
Subfield: Computer Vision and Pattern Recognition
Field: Computer Science
Domain: Physical Sciences
The Persistent Complex Bereavement Inventory: A Measure Based on the <i>DSM-5</i>

The Persistent Complex Bereavement Inventory (PCBI) was developed to facilitate research into the construct of persistent complex bereavement disorder (PCBD). Across 2 studies, the PCBI yielded a stable 3-factor structure that corresponded with DSM-5 criteria for PCBD. The PCBI demonstrated solid reliability in the forms of internal consistency and test-retest reliability. Correlation analyses provided evidence of the measure's construct, convergent, and divergent validity. The PCBI predicted outcomes, above and beyond measures of prolonged grief disorder, separation anxiety, depression, and post-traumatic stress. In addition, the Social/Identity Disruption subscale was able to predict future negative religious coping, harmful health behaviors, hallucinations, somatic complaints, medical conditions, and suicidal ideation. This article provides preliminary evidence for a reliable and valid way to measure PCBD symptomatology.

Topic: Grief, Bereavement, and Mental Health
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Focus on Teacher Education: Social Studies and the Black Male: Culturally Responsive Curricula

At a 2010 meeting at the National Press Club, then U.S. Secretary of Education, Arne Duncan, offered the following challenge:The truth is—there are indefensible inequities in our school system—in t...

Topic: Educator Training and Historical Pedagogy
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Implicit Cognitive Distortions and Sexual Offending

This work develops and tests the semantic-motivation hypothesis of sexual offenders' implicit cognitions. This hypothesis posits that sexual offenders' cognitive distortions emerge at the interface between implicit motivation and cognition. The semantic-motivation hypothesis is used to guide the development of 3 implicit association tests (IATs). These IATs were used to test for the existence of 3 expected child sexual offender implicit cognitive distortions in child sexual offenders ("children as sexual beings," "uncontrollability of sexuality," and "sexual entitlement-bias"). Results showed that child sexual offenders had larger IAT effects than did mainstream offenders and male and female nonoffenders for the "children as sexual beings" and the "uncontrollability of sexuality" implicit theories. Child sexual offenders also had a larger IAT effect than male and female nonoffenders for the "sexual entitlement-bias" implicit theory. Implications for the semantic-motivation hypothesis are discussed.

Topic: Psychopathy, Forensic Psychiatry, Sexual Offending
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Supplementary Figure 1 from A Human Single-Domain Antibody Elicits Potent Antitumor Activity by Targeting an Epitope in Mesothelin Close to the Cancer Cell Surface

&lt;p&gt;PDF file - 1308K, Production and analysis of the SD1-based recombinant immunotoxin.&lt;/p&gt;

Topic: Toxin Mechanisms and Immunotoxins
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
COVID-19 leadership challenges in knowledge work

Considerable attention has been paid to employees’ experiences when working from home (WFH) during the COVID-19 pandemic, including their well-being and performance. However, less attention has been paid to how managers experience WFH and how this may challenge them in their new role as distance managers. This study investigates how managers of knowledge work experienced distance management during COVID-19. An international survey was distributed in the first weeks of the Danish national lockdown and collected data in spring 2020. Based on Danish responses from 1053 employees and 290 managers of knowledge work, who had limited prior experience in distance management, our analysis revealed 12 items where managers found their work during lockdown to be more challenging than employees did. The implications are that research and practice should consider the well-being and performance consequences of WFH not only for employees but also for managers, as their experiences differ, and the managers express challenges in their leadership.

Topic: Team Dynamics and Performance
Subfield: Social Psychology
Field: Psychology
Domain: Social Sciences
Origin of karstic bauxite: Evidence against carbonate rock weathering residues and for lateritic bauxite

This dataset contains bulk-rock major and trace element compositions of global karstic bauxite (Table S1), bulk-rock major and trace element compositions of global lateritic bauxite (Table S2), raw data of major and trace element compositions of soil and stream sediment in Guangxi region (Table S3), concentration of SiO2 in karstic groundwater (Table S4), bulk-rock major element compositions of carbonate rock (Table S5), and mineral and major element compositions of karstic soil (Table S6).

Topic: Medication Adherence and Compliance
Subfield: Family Practice
Field: Medicine
Domain: Health Sciences
[Epidemiology of tuberculosis. Continued increase in resistant pathogens?].

Up into the eighties, such institutions as the WHO and the Center for Disease Control and Prevention in the USA were confident that tuberculosis would be eradicated by the start of the 21st century. Since then, however, tuberculosis has made such a vigorous comeback that in 1993, the WHO was prompted to call it a "global health emergency". The improverishment of large areas of the planet, resulting in an absence of elementary standards of medical care, in concert with population growth and the HIV epidemic, led to a dramatic increase in the incidence and deadliness of tuberculosis, as also in the incidence of resistant strains of the tuberculosis pathogen in many countries. As a result of migration, however, this development is not confined to such countries, but has also become a major problem in the developed countries, including Germany.

Topic: Tuberculosis Research and Epidemiology
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
The Effect of Environment on Galaxy Spiral Arms, Bars, Concentration, and Quenching

For a sample of 4378 nearby spiral and S0 galaxies, Yu and Ho (2020) used Fourier analysis of Sloan Digital Sky Survey images to show that the strengths of the spiral arms and the pitch angles of the arms are inversely correlated with central concentration. In the current study, we search for trends in the Yu and Ho (2020) spiral arm parameters with environment and specific star formation rate (sSFR). When comparing galaxies with similar concentrations, we do not find a significant difference in the arm strengths or pitch angles of spiral galaxies in clusters compared to field galaxies. When differences in concentration are taken into account, we also find no significant difference in the parameter f3 for cluster spirals compared to field spirals, where f3 is the normalized m = 3 Fourier amplitude. When concentration is held fixed, both arm strength and pitch angle are correlated with sSFR, but f3 is not. These relations support the suggestion by Davis et al. (2015) of a `fundamental plane' of spiral structure involving pitch angle, bulge stellar mass, and gas surface density. We discuss these results in terms of theories of spiral arm production and quenching in galaxies. To aid comparison with earlier studies based on Galaxy Zoo, we explore how the Yu and Ho (2020) parameters relate to similar parameters measured by Galaxy Zoo (i.e., f3 vs. number of arms, pitch angle vs. winding parameter, and concentration vs. bulge class).

Topic: Galaxies: Formation, Evolution, Phenomena
Subfield: Astronomy and Astrophysics
Field: Physics and Astronomy
Domain: Physical Sciences
RETRACTED: Chung et al. Long-Lasting Exendin-4-Loaded PLGA Nanoparticles Ameliorate Cerebral Ischemia/Reperfusion Damage in Diabetic Rats. J. Pers. Med. 2022, 12, 390

The Journal retracts the article “Long-Lasting Exendin-4-Loaded PLGA Nanoparticles Ameliorate Cerebral Ischemia/Reperfusion Damage in Diabetic Rats” [...]

Topic: Advanced Glycation End Products research
Subfield: Clinical Biochemistry
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Measure of nonplanarity in conjugated organic molecules: which structurally characterized molecule displays the highest degree of pyramidalization? [Erratum to document cited in CA112(21):197274c]

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMeasure of nonplanarity in conjugated organic molecules: which structurally characterized molecule displays the highest degree of pyramidalization? [Erratum to document cited in CA112(21):197274c]R. C. HaddonCite this: J. Am. Chem. Soc. 1990, 112, 22, 8217Publication Date (Print):October 1, 1990Publication History Published online1 May 2002Published inissue 1 October 1990https://pubs.acs.org/doi/10.1021/ja00178a085https://doi.org/10.1021/ja00178a085research-articleACS PublicationsRequest reuse permissionsArticle Views66Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Topic: Surface Chemistry and Catalysis
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
supplementary_table_2 – Supplemental material for iTRAQ-based proteomics reveals SOD2 as a potential salivary biomarker in liver cancer

Supplemental material, supplementary_table_2 for iTRAQ-based proteomics reveals SOD2 as a potential salivary biomarker in liver cancer by Feng Ding, Kehuan Sun, Ningning Sun, Qianqian Jiang, Meiqun Cao and Zhengzhi Wu in The International Journal of Biological Markers

Topic: Salivary Gland Disorders and Functions
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Integrated Home-Based Palliative Care in Motor Neuron Disease: A Case Report from Low- Middle Income Country

In many international care guidelines, multidisciplinary palliative care forms a key to optimum management in Motor Neuron Disease (MND). We describe the home-based palliative care interventions for a client with MND and his family from a Low and Middle-income country context. This report also discusses the advantages and challenges of the same with suggestions for sustaining the quality of care for neuro palliative conditions.

Topic: Amyotrophic Lateral Sclerosis Research
Subfield: Neurology
Field: Medicine
Domain: Health Sciences
Composite wall‐to‐wall polymerization contraction in dentin cavities treated with various bonding agents

Abstract – Extracted human teeth are frequently used in studies on bonding of composites to dentin. However, little is known about the effect of storing conditions on the results recorded. The purpose of the present work was to measure the wall‐to‐wall polymerization contraction of a light‐cured composite material with and without the use of five different dentin bonding agents in cylindrical dentin cavities prepared in extracted human teeth, either fresh or after storing for up to 4 wk in four different media. No effect of the storing conditions on the width of contraction gaps could be demonstrated when the teeth were stored either in tap water or in a 1.0% aqueous chloramine solution. Aqueous solutions of either 0.1% benzalkonium chloride or 0.9% sodium chloride did occasionally affect the size of the contraction gap.

Topic: Dental materials and restorations
Subfield: Orthodontics
Field: Dentistry
Domain: Health Sciences
State lotteries and legalized gambling: painless revenue or painful mirage

Preface Lotteries: History, Controversies, and Current State The Three Waves of Lottery Activity in the United States Lotteries and Gambling as a Worldwide Phenomenon The Triumph of the Ethics of Tolerance: The Evolution of Lotteries in the Public Policy Process The Strategic Management of Lotteries Lottery Games and the Various Strategies for Conducting Lotteries Lottery Sales and Other Forms of Gambling: Possible Cannibalization and Other Consequences The Expansion of State-Sponsored Gambling Activities: The Cases of Massachusetts and Pennsylvania The Future of Lotteries and Legalized Gambling Privatization and Other Strategic Issues Concerning the Regulation of Gambling Concluding Remarks on Lotteries and Gambling Bibliography Index

Topic: Gambling Behavior and Treatments
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences