jimnoneill/paper-to-field-training huggingface dataset:
Whole-body X-irradiation of Mice Accelerates Polyploidization of Hepatocytes

Male C57BL/6 mice were whole-body irradiated with 4.75 Gy of X-rays at the age of 2 months and killed at 2, 6, 12 and 19 months after irradiation. The percentage survival began to decline earlier and faster in the irradiated group than the controls up to 19 months after exposure when the study was terminated. The nuclear DNA content of individual hepatocytes was measured by a Feulgen-DNA microfluorometric method, and hepatocytes were classified into various ploidy classes. In the irradiated mice, the degree of polyploidization was significantly higher than the controls by 2 months after exposure and steadily increased up to 6 months after exposure. Thereafter, however, a slow return to the control level was found up to 19 months after irradiation. These results appear to support a hypothesis that radiation accelerates the ageing process as judged from hepatocyte polyploidization.

Topic: CRISPR and Genetic Engineering
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Physical and Chemical Characteristics of Pearl Millet Grains and Their Relationship to Roti Quality

ABSTRACT Physical characteristics such as swelling capacity of grain and flour and water‐soluble flour fraction, and chemical characteristics such as protein, starch, amylose, soluble sugars and fat content in pearl millet ( Pennisetum americanum (L.) Leeke ) grains from 20 cultivars comprising local types, popular hybrids and prerelease lines were determined. Rotis were made from the grains of the 20 cultivars and evaluated for color, texture, odor, taste, and acceptability by a trained taste panel. The correlations between physicochemical characters and roti quality of 20 cultivars were worked out. The swelling capacity, water‐soluble flour fraction, water‐soluble protein, and amylose content of flour influenced the roti quality.

Topic: Food composition and properties
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Read [PDF] Books John Coltrane - Omnibook: for B-flat Instruments Full PDF

Read Or Download John Coltrane - Omnibook: for B-flat Instruments Full Books By John Coltrane\n\nRead Online =&gt; Read John Coltrane - Omnibook: for B-flat Instruments\n\nDownload Book =&gt; Download John Coltrane - Omnibook: for B-flat Instruments\n\nJohn Coltrane - Omnibook: for B-flat Instruments pdf download\nJohn Coltrane - Omnibook: for B-flat Instruments read online\nJohn Coltrane - Omnibook: for B-flat Instruments epub\nJohn Coltrane - Omnibook: for B-flat Instruments vk\nJohn Coltrane - Omnibook: for B-flat Instruments pdf\nJohn Coltrane - Omnibook: for B-flat Instruments amazon\nJohn Coltrane - Omnibook: for B-flat Instruments free download pdf\nJohn Coltrane - Omnibook: for B-flat Instruments pdf free\nJohn Coltrane - Omnibook: for B-flat Instruments pdf\nJohn Coltrane - Omnibook: for B-flat Instruments epub download\nJohn Coltrane - Omnibook: for B-flat Instruments online\nJohn Coltrane - Omnibook: for B-flat Instruments epub download\nJohn Coltrane - Omnibook: for B-flat Instruments epub vk\nJohn Coltrane - Omnibook: for B-flat Instruments mobi\n\n\n#downloadbook #book #readonline #readbookonline #ebookcollection #ebookdownload #pdf #ebook #epub #kindle

Topic: Hermeneutics and Narrative Identity
Subfield: Philosophy
Field: Arts and Humanities
Domain: Social Sciences
mer-Trichlorotris(2,3-dihydrobenzo[b]thiophene-S)rhodium(III)

The Rh atom has a distorted octahedral geometry. Two of the benzothiophenyl ligands occupy trans equatorial positions with Rh-S distances [2.351 (1) and 2.369 (1) A] which are significantly longer than the third [2.330 (1) A] distance. The Rh-Cl distances are in the range 2.333 (2)-2.359 (1) A. The benzothiophenyl ligand at the axial position is inclined at almost right angles [mean-planes angles 89.6 (2) and 79.5 (2) o ] to the other two ligands which lie almost parallel to each other [mean-planes angle 10.4 (2) o ]

Topic: Metal complexes synthesis and properties
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Atopic Dermatitis

Atopic dermatitis (AD; atopic eczema, eczema) is an inflammatory, chronically relapsing, and intensely pruritic skin disease occurring often in families with atopic diseases (atopic dermatitis, bronchial asthma, and/or allergic rhino-conjunctivitis). AD is a noncontagious inflammation of the epidermis and dermis with characteristic clinical (itch, erythema, papule, seropapule, vesicle, squames, crusts, lichenification, in synchronous, or metachronous polymorphy) and dermatopathological (spongiosis, acanthosis, hyper-and parakeratosis, lymphocytic infiltrates, and exocytosis, eosinophils) signs. With a prevalence of 2% to 5% (in children and young adults around 15%), AD is one of the most common skin diseases. The varying etiologic concepts of this disease are mirrored by the different names that are or have been used: “neurodermatitis,” “neurodermitis,” and “endogenous eczema” are just a few examples of current terms. Atopy is a strikingly common finding in these patients (Hanifin and Rajka 1980). It can be defined as familial hypersensitivity of the skin and the mucosa to environmental substances, associated with increased production of immunoglobulin E (IgE) and/or altered pharmacologic reactivity (Ring et al. 2006; Ring 2004). More recently, a new definition for atopy, restricted to IgE production, has been proposed: “a personal or familial tendency to produce IgE antibodies in response to low doses of allergens, usually proteins, and to develop typical symptoms such as asthma, rhinoconjunctivitis, or eczema/dermatitis” (Johansson et al. 2004, pp. 832-836).

Topic: Dermatology and Skin Diseases
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Study of Co/Pd multilayers as a candidate material for next generation magnetic media

We report a combinatorial synthesis study on the magnetic properties of sputter-deposited Co/Pd multilayers with high perpendicular anisotropy and high remnant squareness for magnetic media applications such as magnetic logic systems, bit patterned media, magneto-optical recording, and multilevel three-dimensional (3D) magnetic media. The perpendicular magnetic anisotropy in the multilayers originates from the interfacial anisotropy of the alloylike structure. The deposition conditions and subsequent microstructures of the multilayers are critical factors to determine the magnetic properties of the media. We investigated the dependence of the magnetic properties on the thickness of Co and Pd layers the number of Co/Pd bilayers. For instance, we found that a 0.26-nm-thick layer of Co would produce the highest coercivity value if paired with a 0.55-nm-thick Pd layer. Our results revealed that an Ar+ milling could significantly increase the coercivity of the multilayer media. Further, we discovered that we could control the deposition pressure to achieve either granular or continuous media morphologies corresponding to exchange-coupled or decoupled grains, respectively. Finally, we used the combinatorial synthesis to tailor multilayers’ properties to engineer a eight-level three-layer 3D media.

Topic: Magnetic properties of thin films
Subfield: Atomic and Molecular Physics, and Optics
Field: Physics and Astronomy
Domain: Physical Sciences
Atypical Extrapulmonary Presentations Of Severe Respiratory Syncytial Virus Infection Requiring Intensive Care

The patterns and nature of a four-month epidemic of severe respiratory syncytial virus (RSV)-associated disease were analyzed using presenting, demographic, clinical, and therapeutic data. Of 218 infants with RSV infection admitted to Rainbow Babies and Childrens Hospital, 49 (22.4%), most born prematurely, entered the pediatric intensive care unit (PICU). Fluorescent antibody and/or enzyme-linked immunosorbent assay documented RSV infection. PICU patients underwent airway stabilization; 53.5% were intubated and evaluated for sepsis. Patients with positive bacterial cultures received antibiotics; 18% were given ribavirin. Patterns of infection included hypothermia, septic shock appearance, apnea, pneumonia, and wheezing due to bronchiolitis. The average age difference between patients with hypothermia (23.3 days) and those with pneumonia (11.2 months) was statistically significant. There were no significant differences in average age, gestational age at birth, number intubated, worst pH and PCO 2 , duration of intensive care, or treatment modalities between infants with bronchopulmonary dysplasia who received ribavirin and those who did not.

Topic: Respiratory viral infections research
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Very low internal loss, 1.5 μm wavelength SCH-MQW InGaAsP/InP laser diodes with broadened-waveguides

We have shown that the cladding layer free-carrier absorption is the main source of internal loss in the studied InGaAsP/InP SCH-MQW laser structures. Very low internal loss (1.3 cm/sup -1/) and low threshold current density (260 A/cm/sup 2/ for a 2 mm cavity) are obtained with the broadened-waveguide laser structure. High efficiency lasers can be made using this structure.

Topic: Semiconductor Lasers and Optical Devices
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Exploring the Correlation between TNC Gene and Osteoporosis

Introduction: Osteoporosis is one of the main causes of bone fractures in old age. The examination of osteoporosis in the elderly is very complicated due to the heterogeneity of the aging process. This study aimed to investigate the correlation of the TNC gene in the patients with an inherited and very rare osteoporosis syndrome. The importance of this study was the identification of a specific biomarker for the osteoporosis process in a monogenic disease. Methods: In this case-control study, the patients with Osteogenesis Imperfecta were used as a simple and monogenic model to investigate the possibility of TNC gene role in osteoporosis. For this purpose, TNC protein network and its related biological pathways were firstly evaluated by bioinformatic analysis. Then, skin biopsies were taken from 3 patients with inherited osteoporosis syndrome called Osteogenesis Imperfecta and two healthy individuals. After culturing the biopsy, fibroblast cells were isolated from keratinocyte cells. Then, the total RNA of each sample was extracted from two different passages and cDNA was synthesized. Subsequently, the expression of TNC gene was measured by Real-time PCR in healthy and patient cells using various replicates. Results: TNC network proteins are significantly associated with the biological pathways involved in the ossification process. The expression of the TNC gene was assessed in wild type and patient cells. Finally, our results confirmed a significant increase in the expression of TNC in the patients’ compared to wild types’ cells by using technical and biological replicates (p:0.005, p:0.007) and Student t-test. In this study, Excel and GraphPad Prism 5.0 software (GraphPad Software, Inc., San Diego, CA) were used. Conclusion: Increased expression of TNC gene in a monogenic osteoporosis syndrome can indicate the potential role of this gene in the process of bone loss and introduce this gen as a new biomarker for osteoporosis. The study on rare Osteogenesis Imperfecta syndrome is a simple and monogenic model to investigate the heterogeneous osteoporosis. Therefore, the expression of the candidate gene needs to be evaluated and confirmed in an appropriate statistical population composed of patients with osteoporosis.

Topic: Connective tissue disorders research
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
INCREASE OF THE BEARING ABILITY OF THE COLUMNS STRENGTHENED BY INHALINGS

The article considers the behavior of the columns strengthened by horizontal struts in one and two levels. The shafts of the pillars are taken from conventional steel and wood. Sets out the detailed calculation of the columns, graphics are given of the consumption of metal. Conclusions.

Topic: Structural mechanics and materials
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Transformations of the Language of Diplomatic Correspondence between the Entente Countries and Germany before The First World War

The spheres of official communication, which include public administration, legal proceedings, legislation, etc., are regulated, in contrast to everyday communication. Activities in each of these spheres are subject to precisely defined, strictly established rules that regulate and legitimize it. The diplomatic language is characterized by a special degree of regulation. “The weight of a word” in international politics is extremely heavy, since the fate of entire states and peoples may depend on successful or unsuccessful communication between diplomats. The strict standardization of the diplomatic language should serve as a kind of deterrent against the growth of tension in international relations. The goal of this study is to identify the degree of susceptibility of the diplomatic correspondence language to transformations in the political crisis context (during wartime). The research material is based on the texts from the Orange book, a collection of diplomatic correspondence between warring countries before the outbreak of the First World War. The application of the contextual analysis method made it possible to determine the vector of changes in the diplomatic correspondence language caused by the political crisis: from restraint, emotionlessness, tact and politeness accepted in the diplomatic sphere to ultimatumness, categoricalness, manifestation of emotions and deviation from the principle of objective reflection of events.

Topic: Language, Communication, and Linguistic Studies
Subfield: Communication
Field: Social Sciences
Domain: Social Sciences
Electrochemical and electron paramagnetic resonance studies of a series of 1,4-diphosphoniacyclohexa-2,5-diene salts. Electrochemical generation of the radical cations of a series of diphosphabenzene compounds

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectrochemical and electron paramagnetic resonance studies of a series of 1,4-diphosphoniacyclohexa-2,5-diene salts. Electrochemical generation of the radical cations of a series of diphosphabenzene compoundsReuben D. Rieke, Robert A. Copenhafer, C. K. White, Adam Aguiar, John C. Williams Jr., and M. S. ChatthaCite this: J. Am. Chem. Soc. 1977, 99, 20, 6656–6662Publication Date (Print):September 1, 1977Publication History Published online1 May 2002Published inissue 1 September 1977https://pubs.acs.org/doi/10.1021/ja00462a030https://doi.org/10.1021/ja00462a030research-articleACS PublicationsRequest reuse permissionsArticle Views51Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Topic: Synthesis and characterization of novel inorganic/organometallic compounds
Subfield: Inorganic Chemistry
Field: Chemistry
Domain: Physical Sciences
[Profile of the community health nurse].

This article highlights the profile of the community health nurse in the South African context. Our changing society and also the move in emphasis to primary health care services places great emphasis on the important role of the community health nurse in the health services of the future. A brief historical overview gives the development of the training for community health nurses in this country from the traditional health visitor, to the present day comprehensive basic training where community health is seen as part of the basic training for nurses. The answer to questions such as who and what is the community health nurse in South Africa is discussed and some essential characteristics of this nurse are described. Recent South African Nursing Council statistics reveal that only 7 percent of all registered nurses have the additional qualification in community health. Other statistics provide a view on numbers of registered nurses with the additional qualification in the different race groups.

Topic: Interprofessional Education and Collaboration
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
Interpersonal Conflict and Turnover Intention: The Mediating Role of Psychological Well-Being

The purpose of the study is to examine the direct effect of interpersonal conflict on turnover intention and indirect effect of psychological well-being between interpersonal conflict and turnover intention. The data was collected from IT executives working in Malaysian Software companies (n = 396). PLS-SEM technique was used to test the research model. The results of the study indicate that interpersonal conflict positively affects turnover intention while psychological well-being mediates the relationship between interpersonal conflict and turnover intention. The results revealed that the intervention of psychological well-being at workplace help to minimize the turnover intention of IT executives. Additionally, these findings might help IT practitioners to design psychological well-being policy to retain employees. This study establishes a noteworthy gap in the literature to find a mediation link of psychological well-being between interpersonal conflict and turnover intention. © 2017 American Scientific Publishers. All rights reserved.

Topic: Organizational and Employee Performance
Subfield: Artificial Intelligence
Field: Computer Science
Domain: Physical Sciences
Using Twentieth-Century U.S. Weather Modification Policy to Gain Insight into Global Climate Remediation Governance Issues

Abstract With atmospheric greenhouse gas concentrations increasing and binding agreements to reduce anthropogenic emissions wanting, interest in geoengineering as a climate remediation option to be used in tandem with climate change mitigation is growing. Solar radiation management (SRM), due to its relatively low financial cost and the potential for near-term reduction in average global temperature, is gaining particular attention despite the risks of its use, both identified and unanticipated. This paper considers the structure—the participants, positions, actions, outcomes, information, and positive and negative payoffs—of U.S. weather modification research and governance developed between 1947 and 1980, offering a case study that may be useful in thinking through how to move forward with SRM development and governance should a decision be made to contemplate augmenting mitigation and adaptation with geoengineering.

Topic: Climate Change and Geoengineering
Subfield: Global and Planetary Change
Field: Environmental Science
Domain: Physical Sciences
The Blood-Cerebrospinal Fluid Barrier in Man

The concept of a barrier between blood and cerebrospinal fluid (CSF) has its origins in the many observations concerning the relative exclusion of certain drugs from the fluids of the central nervous system. A standardized technique was developed for a study of the quantitative aspects of transfer of drugs or metabolites across the blood-cerebrospinal fluid barrier in the dog. 1 These drug distribution studies indicated that the plasma-CSF barrier is less of a special barrier than had been realized, and that, as far as the behavior of certain organic compounds, it would appear to have properties similar to other biological membranes. As with other membranes, the primarily lipoid nature of this barrier has been noted. 1-3 Drugs which enter CSF rapidly and extensively are in general lipoid soluble and undissociated at body pH. Those drugs excluded from CSF are lipoid insoluble and dissociated at body pH since ionized moieties do

Topic: Pharmacological Effects and Toxicity Studies
Subfield: Pediatrics, Perinatology and Child Health
Field: Medicine
Domain: Health Sciences
ChemInform Abstract: An Efficient Large Scale Synthesis of Coumarins by a Dealkylative Boron‐Mediated Ring Closure of 3‐(ortho‐Methoxyaryl)propenoic Esters.

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Topic: Synthesis of Organic Compounds
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
“Ungovernable Feelings and Passions”: Common Sense Philosophy and Mental State Defences in Nineteenth Century Scotland

During the nineteenth century, changing conceptions of mental disorder had profound implications for the way that criminal responsibility was conceived. As medical writers and practitioners increasingly drew attention to the complexities of insanity, the grounds on which mentally abnormal offenders could be excused began to seem unduly restrictive. By way of a contribution to our understanding of this development, this article examines how the growing disparity unfolded in Scotland. The author argues that the requirements of the insanity defence, as set out within judicial directions, reflect core facets of Scottish Common Sense philosophical thought, including Thomas Reid's view of human agency and understanding of ‘common sense’. Building on this contention, the author suggests that Scottish Common Sense philosophy played an important role in the development of Scottish mental state defences more broadly, and can provide an original interpretation of the way the doctrines of provocation and diminished responsibility changed during this era.

Topic: Historical Psychiatry and Medical Practices
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Multi-objective network design problem considering system time minimization and road safety maximization

This paper discusses the Network Design Problem (NDP) solved for travel time minimization and road safety maximization. Similarly to other NDP models, the model is formulated as a bi-level multi-objective optimization problem. The estimation of the system time benefit and safety benefit is performed using previously developed methods, and the optimal solutions are found using the multi-objective genetic algorithm. The proposed method is demonstrated on a real-size network, using a large set of candidate projects.

Topic: Transportation Planning and Optimization
Subfield: Transportation
Field: Social Sciences
Domain: Social Sciences