jimnoneill/paper-to-field-training huggingface dataset:
A Review On Solution Focused Brief Therapy Studies In Turkey

The aim of this study is to examine experimental studies conducted with solution focused brief therapy psychological counselling in Turkey. In this study in which descriptive method was used, the data were analysed with document analysis. In this respect, a total of 26 studies, 24 graduate theses and 2 articles, which were conducted experimentally with solution focused counselling approach, were analysed. According to the results of the study, it was found that there was an increase in studies conducted with this approach in recent years, the majority of the studies were conducted in the fields of education and nursing, and the sample groups of the study were mostly secondary school, high school and university students. It was found that mostly group counselling method and semi-experimental pattern were used in studies, a great majority of the studies were conducted with 6 sessions, all of the studies except one included control group, 3 of the studies included placebo group and follow-up test was conducted in 14 of the studies. It was found that the studies were applied on very different problem areas, mainly undesired behaviours and that 4 of the studies met all the criteria determined for solution focused approach. When the studies conducted were examined, it was found that there were no studies in which solution focused approach was compared with another psychotherapy approach. As a result of the study, it was found that in all studies except one, solution focused counselling had a significant effect on the experimental group.

Topic: Counseling, Therapy, and Family Dynamics
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
[Method of damaging rabbit myocardium during the intrauterine period].

The author describes a method used for injury of rabbit fetuses myocardium on the 20-24th days of pregnancy. The abdominal cavity and the uterus of pregnant rats were incised and the amniotic sac and thoracic wall of the fetus -- punctured, thus injuring the heart. Two methods were used: in the first case the amniotic sac was completely drawn out from the uterine cavity, and in the other case -- it remained in the uterus and was punctured through the uterine incision. If the operation was not followed by abortion the animals gave birth to viable full-term rabbits.

Topic: Congenital Anomalies and Fetal Surgery
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Optimalization of reaction time through imagery and concentration training in fencing

This study aims to investigate the effect of imagery training and concentration on the reaction time of students taking fencing extracurricular activities. It was a quasi-experimental research using quantitative approach. A total of 15 respondents were classified into 3 groups, which were control (K) and two experimental groups. Students in experimental groups were given imagery training (E1) and concentration training (E2) for six weeks and reaction times were measured using Electronic Fencing Target-1 (EFT-1) before and after the exercise was given. Data were analyzed using descriptive and inferential statistic using paired t-test and Anova one way, and significance level was set at p=0.05. The results found that the imagery and concentration training had a positive impact on the decrease of reaction time, with significance values of 0.008 and 0.005, respectively. From these results it can be concluded that imagery and concentration exercises can help players to improve their reaction time, so that fencers can react quickly to every movement. OPTIMALISASI WAKTU REAKSI MELALUI LATIHAN IMAGERY DAN KONSENTRASI DALAM OLAHRAGA ANGGAR AbstrakPenelitian ini bertujuan untuk mengetahui pengaruh latihan imagery dan konsentrasi terhadap kecepatan waktu reaksi pada siswa yang mengikuti ekstrakulikuler anggar. Penelitian ini merupakan penelitian eksperimen semu yang menggunakan pendekatan kuantitatif. Sebanyak 15 orang responden dikelompokkan menjadi 3 kelompok, yaitu satu kelompok kontrol (K) dan dua kelompok eksperimen yang diberi latihan imagery (E1) dan latihan konsentrasi (E2). Latihan dilakukan selama enam minggu dan waktu reaksi diukur sebelum dan sesudah latihan diberikan menggunakan Electronic Fencing Target-1 (EFT-1). Analisis data dilakukan secara deskriptif dan inferensial menggunakan uji paired t-test dan Anova one way, dengan nilai signifikan ditetapkan sebesar 0.05. Hasil analisis didapatkan bahwa latihan imagery dan konsentrasi yang diberikan kepada responden memberikan dampak positif terhadap penurunan waktu reaksi, dengan nilai signifikansi secara berturut-turut sebesar 0.008 dan 0.005. Dari hasil ini dapat disimpulkan bahwa latihan imagery dan konsentrasi dapat membantu pemain untuk meningkatkan kemampuan reaksi, sehingga pemain anggar dapat bereaksi dengan cepat terhadap setiap gerakan.

Topic: Sports and Physical Education Research
Subfield: Physical Therapy, Sports Therapy and Rehabilitation
Field: Health Professions
Domain: Health Sciences
Therapeutic needs from early childhood in four patients with 21-hydroxylase deficiency harboring the P30L mutation on one allele

21-hydroxylase deficiency (21-OHD) is the most common type of congenital adrenal hyperplasia. Phenotypically, 21-OHD can be divided into classical and non-classical (NC) forms. The genotype-phenotype correlation in 21-OHD is well established. The P30L mutation is usually associated with the NC form and common among Japanese patients with the NC form of 21-OHD. Herein, we report the clinical course of four patients with 21-OHD with the P30L mutation on one allele and loss-of-function variants on the other allele. Contrary to the findings of most previous studies, all patients were treated with hydrocortisone, and two required fludrocortisone therapy in early childhood. The management strategies for patients with 21-OHD, especially those with the P30L mutation on at least one allele, should be determined based on the clinical phenotype predicted by the <i>CYP21A2</i> genotype and individual clinical symptoms and biochemical data.

Topic: Sexual Differentiation and Disorders
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Breaking the Linear-Memory Barrier in MPC: Fast MIS on Trees with Strongly Sublinear Memory

Recently, studying fundamental graph problems in the \emph{Massively Parallel Computation (MPC) framework, inspired by the MapReduce paradigm, has gained a lot of attention. An assumption common to a vast majority of approaches is to allow $\widetildeΩ(n)$ memory per machine, where $n$ is the number of nodes in the graph and $\widetildeΩ$ hides polylogarithmic factors. However, as pointed out by Karloff et al. [SODA'10] and Czumaj et al. [STOC'18], it might be unrealistic for a single machine to have linear or only slightly sublinear memory. In this paper, we thus study a more practical variant of the MPC model which only requires substantially sublinear or even subpolynomial memory per machine. In contrast to the linear-memory MPC model and also to streaming algorithms, in this low-memory MPC setting, a single machine will only see a small number of nodes in the graph. We introduce a new and strikingly simple technique to cope with this imposed locality. In particular, we show that the Maximal Independent Set (MIS) problem can be solved efficiently, that is, in $O(\log^3 \log n)$ rounds, when the input graph is a tree. This constitutes an almost exponential speed-up over the low-memory MPC algorithm in $O(\sqrt{\log n})$-algorithm in a concurrent work by Ghaffari and Uitto [SODA'19] and substantially reduces the local memory from $\widetildeΩ(n)$ required by the recent $O(\log \log n)$-round MIS algorithm of Ghaffari et al. [PODC'18] to $n^α$ for any $α&gt;0$, without incurring a significant loss in the round complexity. Moreover, it demonstrates how to make use of the all-to-all communication in the MPC model to almost exponentially improve on the corresponding bound in the $\mathsf{LOCAL}$ and $\mathsf{PRAM}$ models by Lenzen and Wattenhofer [PODC'11].

Topic: Complexity and Algorithms in Graphs
Subfield: Computational Theory and Mathematics
Field: Computer Science
Domain: Physical Sciences
CCDC 795844: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Supplemental Figures from v-Src Oncogene Induces Trop2 Proteolytic Activation via Cyclin D1

&lt;p&gt;Supplemental Figure 1. Trop2 ICD abundance is maintained by Src kinase. Supplemental Figure 2. Canertinib, a tyrosine kinase inhibitor targeting EGFR reduces cell proliferation but does not affect Trop2 ICD abundance. Supplemental Figure 3. Schematic representation of the mechanism by which Src induction of cyclin D1 enhances cleavage of the membrane associated Trop2 complex to thereby enhance Trop2 ICD. Supplemental Figure 4. Human prostate cancer Tissue Microarray (TMA) IHC staining.&lt;/p&gt;

Topic: Cancer Genomics and Diagnostics
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Social behavior and cooperative breeding in a precocial species: The Kalij Pheasant (<i>Lophura leucomelanos</i>) in Hawaii

ABSTRACT We examined social behavior and documented cooperative breeding in Kalij Pheasants (Lophura leucomelanos) in an introduced population in Hawaii, only the third reported instance of cooperative breeding in Phasianidae. Birds in 31 distinct social groups occupied overlapping home ranges, and group composition remained relatively constant over the 3-yr study period. Each social group contained 1 breeding female and 1 to 6 males. One male was socially dominant in each multiple-male group. Age was the only factor found to determine within-group dominance, suggesting that subordinate males may gain dominance and breeding status by staying in the group. All adults exhibited cooperative behavior, including caring for chicks, agonistic behaviors against conspecific intruders, and vigilance against predators. Average population density was high (3.21 residents per ha), which may lead to habitat saturation in this population. The adult sex ratio was male-biased, with an average M:F ratio of 2.1:1.0. Genetic sex identification of egg samples revealed unbiased primary and secondary sex ratios, which suggests that the bias in adult sex ratio may be caused by differential survival and/or dispersal. Paternity analysis of 13 broods revealed that ~68% of offspring were fathered by the dominant male of the social group, while ~17% were fathered by subordinate males in the group, suggesting that helpers gained some direct benefit by sharing reproduction. We suggest that cooperative breeding may be more common in precocial species than conventionally recognized.

Topic: Animal Behavior and Reproduction
Subfield: Ecology, Evolution, Behavior and Systematics
Field: Agricultural and Biological Sciences
Domain: Life Sciences
MP43-17 SONIC HEDGEHOG REGULATION OF COLLAGEN IN THE PENIS

You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Basic Research I1 Apr 2014MP43-17 SONIC HEDGEHOG REGULATION OF COLLAGEN IN THE PENIS Christopher Bond, Kevin McVary, and Carol Podlasek Christopher BondChristopher Bond More articles by this author , Kevin McVaryKevin McVary More articles by this author , and Carol PodlasekCarol Podlasek More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2014.02.1174AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail Introduction and Objectives Cavernous nerve (CN) injury, which occurs during prostatectomy, decreases penile smooth muscle through an apoptotic mechanism, leading to erectile dysfunction (ED). As smooth muscle is lost, collagen production increases and there is a change in subtypes. This occurs in ED patients by a largely undefined mechanism. We’ve shown in previous studies that the sonic hedgehog (SHH) pathway is critical for the response of the penis to denervation. It has recently been suggested that SHH may play a role in renal and pulmonary fibrosis and collagen production during lung embryogenesis. Our preliminary studies suggest that collagen production is responsive to SHH signaling and we hypothesize that SHH may be a regulator of collagen in the penis. Methods Collagen abundance was quantified by trichrome stain and Image J analysis in corpora cavernosal tissue of prostatectomy, diabetic and control (Peyronnie’s) patients, and in rat penis from: 1.) CN crushed, 2.) SHH inhibited, 3.) SHH treated control and CN injured penis, and 4.) Postnatal development time points. Results Our results show that collagen was increased 16% in prostatectomy and 20% in diabetic patients. SHH treatment of the penis at the time of CN injury prevented collagen induction by 20% at 2 days and 7% at 4 days after injury, as SHH became depleted from the delivery vehicle. During the first week after birth smooth muscle is abundant with minimal collagen synthesis. Collagen abundance increased significantly between postnatal day 7 and 13. Conclusions These results show that SHH suppresses collagen induction in response to CN injury. This is an innovative idea with significant potential for intervention and suggests that the SHH pathway sits at the nexus of several key pathways which regulate erectile function. © 2014FiguresReferencesRelatedDetails Volume 191Issue 4SApril 2014Page: e484 Advertisement Copyright & Permissions© 2014MetricsAuthor Information Christopher Bond More articles by this author Kevin McVary More articles by this author Carol Podlasek More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...

Topic: Sexual Differentiation and Disorders
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Characterization of Induced Resistance to Anthracnose in Alfalfa by Races, Isolates, and Species of<i>Colletotrichum</i>

By prior inoculation with race 1 of Colletotrichum trifolii, race 1-resistant, race 2-susceptible cultivars such as Arc can be protected against subsequent infection by race 2. (…). Protection of Arc seedlings against race 2 was highly correlated with increasing spore concentrations of race 1. Arc has no specific genes for resistance to race 2, and a gene for resistance to race 1

Topic: Plant Pathogens and Fungal Diseases
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Influences of population-level factors on suicides in older adults: a national ecological study from Australia

Specific factors increasing risk of suicide for older adults on SA4 level in Australia were living in areas with a higher proportion of male population, a higher proportion of tenant household dwellers and a higher proportion of immigrants from North-West Europe. The different influences of population-level factor on suicide between older men and women indicate the need for targeted suicide prevention activities.

Topic: Suicide and Self-Harm Studies
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Basic Principles of Antifungal Treatment

There are limited classes of antifungal agents available. Patients most at risk of fungal infections are the critically ill and immunocompromised individuals. An essential component of antifungal treatment is source control. Biomarkers are useful for supporting the diagnosis as well as to rule out a fungal infection. Azoles are inhibitors of CYP450 enzymes, and clinicians need to be aware of the risk of drug-drug interactions. Echinocandins have a low toxicity profile but are only available as an intravenous formulation and are generally less effective against moulds. Amphotericin B is a broad-spectrum antifungal agent and the treatment of choice against Mucorales. It can be nephrotoxic and infusion-related reactions occur.

Topic: Antifungal resistance and susceptibility
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Natural Law Modernized

Hobbes, Locke, Hume, and Rousseau are classic modern philosophers, widely consulted in matters of ethics and political theory. In this provocative study David Braybrooke challenges received scholarly opinion by arguing that these canonical theorists took St Thomas Aquinas as their point of reference, reinforcing rather than departing from his natural law theory. The natural law theory of St Thomas Aquinas is essentially a secular theory, says Braybrooke. He argues that Hobbes, Locke, Hume, and Rousseau share a core of thought that not only has roots in St Thomas but offers an alternative to other ethical theories now current. According to Braybrooke, this surviving and reinforced core qualifies as an ethical theory viable by the most sophisticated standards, meeting the main challenges of analytical metaethics, and thus standing up to the scrutiny that any ethical theory must undergo in contemporary philosophical discussions. Braybrooke's study takes the reader into a rich and compelling intellectual universe, one in which medieval natural law theory, widely ignored as obsolete, survives robustly through the modern canon and into the third millennium.

Topic: American Constitutional Law and Politics
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
Clinical skills of medical residents: a review of physical examination.

Students are introduced to techniques of physical examination at medical school. However, their skills are deficient at the time of graduation, and with the increasing shift of clinical teaching away from the bedside and into the conference room it is expected that these skills will weaken in succeeding generations of physicians. A practical and satisfactory method of addressing this problem during internship and residency training has not been forthcoming because of the lack of a regular forum for the teaching of clinical skills in busy tertiary referral hospitals and the shortage of teachers with the necessary skills and commitment to teaching a large number of house staff. We describe a program whose unique hierarchical approach has permitted a detailed ongoing review of physical examination. One clinician was able to teach 24 residents by instructing a small group of senior residents, who in turn, after practising with clinical clerks, taught groups of junior residents.

Topic: Patient Satisfaction in Healthcare
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
Categorical centers and Yetter--Drinfel`d-modules as 2-categorical (bi)lax structures

The bicategorical point of view provides a natural setting for many concepts in the representation theory of monoidal categories. We show that centers of twisted bimodule categories correspond to categories of 2-dimensional natural transformations and modifications between the deloopings of the twisting functors. We also show that dualities lift to centers of twisted bimodule categories. Inspired by the notion of (pre)bimonoidal functors due to McCurdy and Street and by bilax functors of Aguiar and Mahajan, we study 2-dimensional functors which are simultaneously lax and colax with a compatibility condition. Our approach uses a sort of 2-categorical Yang-Baxter operators, but the idea could equally be carried out using a kind of 2-categorical braidings. We show how this concept, which we call bilax functors, generalize many known notions from the theory of Hopf algebras. We propose a 2-category of bilax functors whose 1-cells generalize the notions of Yetter-Drinfel`d modules in ordinary categories, and a type of bimonads and mixed distributive laws in 2-categories. We show that the 2-category of bilax functors from the trivial 2-category is isomorphic to the 2-category of bimonads, and that there is a faithful 2-functor from the latter to the 2-category of mixed distributive laws of Power and Watanabe.

Topic: Algebraic structures and combinatorial models
Subfield: Geometry and Topology
Field: Mathematics
Domain: Physical Sciences
FOUR CASES OF ALPHA-FETOPROTEIN PRODUCING GASTRIC CANCER

We experienced four clinical cases of alpha-fetoprotein (AFP) producing gastric carcinoma. Those four cases were difinitely diagnosed as AFP producing gastric carcinoma, because the serum levels of AFP decreased significantly after surgical removal of the tumors and the localizations of AFP in tumor tissues were demonstrated in all resected specimens by immunohistochemical study (peroxidase-anti-peroxidase; PAP method). It is said that AFP producing gastric carcinomas are characterized by advanced gastric cancer and histologically undifferentiated or poorly differentiated adenocarcinoma.These four cases also had advanced gastric carcinoma, which were histopathologically papillary, medullary, poorly differentiated and well differentiated adenocarcinomas respectively. AFP producing gastric carcinomas are frequently accompanied with liver metastasis and the prognosis is miserable. Of these 4 cases, 2 already had liver metastasis at surgery, and one developed liver metastasis in an early period after surgery. Their prognoses were poor such as one year survival rate of 25% and the 2 year rate of 0%. From the above, the importance of some strategies or efforts for preventing liver metastasis is emphasized even after curative resection could be attained.

Topic: Cholangiocarcinoma and Gallbladder Cancer Studies
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Functions of protein phosphatase-6 in NF-κB signaling and in lymphocytes

Protein phosphatase-6 (PP6) is a member of the PPP family of Ser/Thr phosphatases involved in intracellular signaling. PP6 is conserved among all eukaryotes, and genetics in model organisms indicates it has non-redundant functions relative to other PPP phosphatases. PP6 functions in association with conserved SAPS subunits and, in vertebrate species, forms heterotrimers with Ankrd subunits. Multiple studies have demonstrated how PP6 exerts negative control at different steps of nuclear factor kappaB signaling. Expression of PP6 catalytic subunit and the PPP6R1 subunit is especially high in hematopoietic cells and lymphoid tissues. Recent efforts at conditionally knocking out genes for PP6c or PP6R1 (SAPS1) have revealed distinctive effects on development of and signaling in lymphocytes.

Topic: Protein Tyrosine Phosphatases
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Epictia subcrotilla: Cisneros-Heredia, D.F. &amp; Venegas, P.

Established in 1964, the IUCN Red List of Threatened Species has evolved to become the world’s most comprehensive information source on the global conservation status of animal, fungi and plant species.

Topic: Plant Pathogens and Fungal Diseases
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences