jimnoneill/paper-to-field-training huggingface dataset:
Architect’s vision, creative process and architecture for empowerment: learning from creative process of Indonesian architects

In the course of architect's career, a vision of work is developed. The firm's orientation where the architect works becomes one determining factor of the vision. The vision may change over time based on their professional experiences. At some point, some architects decide to focus only on a particular project, such as architecture for empowerment. This research was conducted by analysing theoretical and empirical studies of architect's creative process. The study was done through a qualitative approach. The participating architects were chosen purposively. Exploration was conducted through deep retrospective interviews. This study aims at: (1) describing the relevance between the architect's vision and his creative process; (2) describing the proportion of combination between problem solving process and the process of self-expression in the creative process in the architecture domain; (3) describing the proportion of combination between problem solving process and self-expression process in architectural creative process for empowerment. The main findings are: (1) every architect develops a personalized creative vision. The architect's creative vision will vary the creative process, although it may not always be the dominating factor of the creative process; (2) in the creative work process, the architect may not always determine the problem solving domination or the self-expression domination as his identity; (3) in the case of architectural design for empowerment, the architect's creative process is dominated by problem solving, even it is possible for the loss of self-expression.

Topic: Creativity in Education and Neuroscience
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
Measurement, Modeling, and Performance, of Indoor MIMO Channels

The objective of this dissertation is to investigate the performance of the recently proposed MIMO technology in real indoor environments based on channel measurements centered at 5.8 GHz. First, a MIMO channel measurement system is implemented based on the virtual antenna array infrastructure. This measurement testbed can acquire the wideband channel matrices of MIMO systems with arbitrary array geometries. The measurement system structure and measurement procedure are described in detail in the first part. The second part is about MIMO channel modeling. Two novel number-of-sources detection algorithms, which are more robust and suitable for practical applications than traditional methods, are proposed. The MIMO path parameters, including delay, DOA, and DOD are estimated from measured data by several estimation schemes based on the ESPRIT algorithm. The accuracies of these estimation schemes are evaluated in terms of the estimation error between the capacities of the directly measured and the reconstructed channels. Moreover, based on ray tracing and measurement results, the spherical wave model is suggested to replace conventional plane wave model in order to prevent the capacity underestimation of short-range MIMO channels. An important observation is that short-range MIMO can achieve full capacity in free space channel. A threshold distance is derived to determine whether the spherical wave model is necessary. In the final part, measurements conducted in the Residential Laboratory are used to investigate the impact of element spacing, LOS, interference, spatial correlation between the interfering and data links, and stream control. A capacity enhancement scheme, which improves the performance by adapting the element locations, is implemented using our measurement system. Finally, the performances of beam selection and antenna selection in combination with MIMO technologies are compared in both narrowband and wideband channels.

Topic: Advanced MIMO Systems Optimization
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Data Supplement from The SIRT1/HIF2α Axis Drives Reductive Glutamine Metabolism under Chronic Acidosis and Alters Tumor Response to Therapy

&lt;p&gt;Supplementary Figure S4. HIF acetylation is regulated by acidosis-triggered SIRT1 activity.&lt;/p&gt;

Topic: Cancer, Hypoxia, and Metabolism
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Core-shell microgels via precipitation polymerization: computer simulations

In this work we presented a novel computational model of precipitation polymerization allowing one to obtain core-shell microgels via a realistic cross-linking process based on the experimental procedure. We showed that the cross-linker-monomer reactivity ratios r are responsible for the microgel internal structure. Values of r lower than 1 correspond to the case when alternating sequences occur at the early reaction stages; this leads to the formation of microgels with pronounced core-shell structure. The distribution of dangling ends for small values of r becomes bimodal with two well-distinguished peaks, which correspond to the core (short dangling ends) and corona (long dangling ends) regions. The density profiles confirm the existence of two distinct regions for small r: a densely cross-linked core and a loose corona entirely consisting of dangling ends with no cross-linker. The consumption of the cross-linker in the course in the microgel formation was found to be in a perfect agreement with the predictions of Monte Carlo (MC) model in the sequence space.

Topic: Hydrogels: synthesis, properties, applications
Subfield: Molecular Medicine
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Occupational-Based Effects of Retirement on Health

Many European countries have recently decided to increase their statutory retirement ages because the demographic change poses a challenge to the stability of social security systems. The success of this policy depends among others on the health effect of such a delayed retirement. This study analyzes the effect of retirement on mental and physical health and further examines whether the health effect depends on the type of occupation. For this purpose, a cross-country analysis is applied on the basis of the Survey of Health, Ageing and Retirement in Europe (SHARE) dataset. To control for endogeneity, country-specific eligibility ages for early and full retirement are used for an instrumental variable approach. Overall, the results suggest a health-preserving effect of retirement as indicated by a 12 percent decrease in the likelihood of reporting bad health and by an improvement in a defined health index by a one-quarter standard deviation. Concerning the occupational-based effects of retirement on health, the results are as expected: Retiring from a blue collar occupation has significant positive effects on health whereas retiring from a white collar occupation influences health negatively. The policy implication of these findings is to increase the statutory retirement ages for white collar workers and to implement special pension schemes for blue collar workers which allow them to retire earlier according to the number of years they have been working in a physically harmful occupation.

Topic: Retirement, Disability, and Employment
Subfield: Demography
Field: Social Sciences
Domain: Social Sciences
Design and Polarimetric Calibration of Dual-Polarized Phased Array Feeds for Radio Astronomy

Research institutions around the globe are developing phased array feed (PAF) systems for wide-field L-band radio astronomical observations. PAFs offer faster survey speeds and larger fields of view than standard single-pixel feeds, which enable rapid sky surveys and significantly increased scientific capability. Because deep space astronomical signals are inherently weak, PAF systems must meet stringent noise and sensitivity requirements. Meeting these requirements requires detailed modeling of the phased array itself as well as the reflector it is mounted on. This thesis details a novel approach to dual-pol PAF design that models the array and reflector as a complete system in order to achieve a more optimal sensitivity and system noise temperature. The design and construction of two arrays designed using this technique is discussed. The implementation of a data acquisition system to receive data from the first of these arrays is also detailed. Polarization state information plays an important role in understanding cosmological processes for many deep space sources. Because of phase and gain imbalances in the LNAs and receiver chains calibration is required for accurate measurement of polarization by phased array feeds. As a result accurate polarimetric calibration techniques are essential for many observations. Existing polarimetric calibration methods are based on assumptions about the form of the system Mueller matrix that limit the generality of the method or require long observations of a polarized source which is time-consuming for multiple PAF beams. This thesis introduces a more efficient method of calibration that uses only three snapshot observations of bright astronomical calibrator sources, one unpolarized and two partially polarized. The design of an engineering array for the Green Bank Telescope is discussed. Measured results from a prototype element are presented along with simulated on-reflector results for the full array. Simulations predict that the array will be the highest sensitivity dual pol feed built by the Radio Astronomy Systems group at Brigham Young University to date.

Topic: Radio Astronomy Observations and Technology
Subfield: Astronomy and Astrophysics
Field: Physics and Astronomy
Domain: Physical Sciences
Choroidal Neovascularization Associated with Morning Glory Syndrome: A Case Report

Morning glory syndrome (MGS) is a congenital optic disc anomaly caused by abnormal closure of the embryonic fissure. Retinal detachment is commonly associated with MGS, though the association of choroidal neovascularization (CNV) with MGS is rare. Herein, we report a case of CNV associated with MGS, which was successfully treated with a single intravitreal injection of bevacizumab. A 32-year-old Japanese woman consulted at our clinic for blurred vision in her left eye for five days. Her best-corrected decimal visual acuity (BCVA) was 1.5 (S-1.0) OS. The fundus examination revealed subretinal hemorrhage associated with MGS in the temporal margin of the optic disc. As she was pregnant, we planned to continue follow-up without further invasive testing and treatment; however, her visit to the hospital was interrupted. Ten months later, she returned with complaints of poor vision and central scotoma in her left eye for six months. The BCVA was 0.5 (S-1.0/C-1.0/45°) OS. The fundus examination showed that subretinal hemorrhage increased, and the subretinal fluid extended below the fovea. Multimodal imaging revealed type 2 CNV on the temporal and nasal disc margins. After she received an intravitreal injection of bevacizumab (1.25 mg), rapid absorption of subretinal fluid and regression of CNV were observed. The BCVA improved to 1.5 (S-0.5/C-0.75/35°) OS. No recurrence of CNV was observed for 26 months after the injection. During the follow-up of MGS cases, we should pay attention, not only to retinal detachment, but also to the occurrence of CNV around the disc margins.

Topic: Retinal and Macular Surgery
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Quality Assessment and Standardization of Samvardhana Ghrita: A Comprehensive Pharmacognostical, Physico-Chemical, and Chromatographic Evaluation

This study aimed to authenticate and evaluate the quality of Samvardhana Ghrita, an Ayurvedic formulation, by analyzing its ingredients and therapeutic properties as outlined in the Ayurvedic Pharmacopoeia of India (API). Raw materials were sourced from local and specialized markets, and the Ghrita was prepared according to API guidelines. The authenticity of key ingredients such as Bala, Atibala, Khadira, Prishniparni, Tinisha, and Kebuka was confirmed through organoleptic evaluation, physico-chemical analysis, and Thin Layer Chromatography (TLC). Organoleptic assessment revealed the preparation's viscous consistency, algae green color, and bitter taste, typical of herbal formulations. Physico-chemical analysis demonstrated low moisture content (0.12%), an iodine value of 35.69, and a saponification value of 235.79 mg KOH/g, confirming stability and quality. TLC analysis identified five distinct retention factors (Rf values), supporting the presence of multiple bioactive components. These results confirm the authenticity, stability, and therapeutic efficacy of Samvardhana Ghrita, supporting its use for promoting child growth and treating conditions like Pangu, Muka, Ashruti, and Jada, as prescribed by Acharya Kashyapa. The study emphasizes the importance of quality control measures for ensuring the safe and effective clinical application of Ayurvedic formulations. Key words: Ayurveda, Atibala, Bala, Kebuka, Khadira, Physico-chemical analysis, Prishniparni, Samvardhana Ghrita, Tinisha, and Thin Layer Chromatography

Topic: Phytochemicals and Medicinal Plants
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Habitat, Succession, Attachment, and Morphology of Segmented, Filamentous Microbes Indigenous to the Murine Gastrointestinal Tract

Some indigenous microorganisms localize on epithelial surfaces in various areas of the digestive tracts of animals. One of these, a segmented, filamentous microbe, localizes on the epithelium in the small bowels of mice and rats. These filamentous microbes colonize mice at weaning time and persist in adult animals for at least 2 months. Results of the study of light and electron micrographs suggest that the microorganisms are procaryotic, and that they interact with small bowel epithelial cells to form an attachment site. This site consists of modified epithelial cell membrane and apical cytoplasm adjacent to the attached bacterium. The microbe fills the site with part of its first segment. This segment has a nipple-like appendage on the end inserted into the epithelial cell. The other segments, which compose the rest of the filament, are usually separated by septa. Many of the individual segments contain intrasegmental bodies that appear to be procaryotic cells. Some of these intrasegmental bodies are similar in morphology to the first segment of each filament inserted into an epithelial cell. These intracellular bodies may be components in the life cycle of the microorganism. The organism has not yet been cultured in recognizable form. Therefore, such a hypothesis cannot be proved as yet, nor can the microbe be classified with certainty. Because it localizes in an epithelial habitat in the small bowel, however, it may be a particularly important microbial type in the gastrointestinal ecosystem of laboratory rodents.

Topic: Probiotics and Fermented Foods
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Modelling the Endothelial Glycocalyx Layer

This thesis concerns the construction of a mathematical model for blood flow in microvessels coated with an endothelial glycocalyx layer (EGL). Special attention is focused on the effect of the wall layer on the system as a whole and the interaction between blood, EGL and the wall vessel. Interest in this problem is motivated by its implications for better understanding of the clinical function of the EGL which is extremely challenging to measure in-vivo. The early parts of this thesis investigate the motion of a rigid particle through a microtube which has a non-uniform wall shape, is filled with a viscous Newtonian fluid, and is lined with a thin poroelastic layer. This is relevant to the transport of small rigid cells (such as neutrophils) through microvessels that are lined with an EGL. We describe a new boundary-integral representation for Biphasic Mixture Theory, which allows us to efficiently solve elastohydrodynamicmobility problems using Boundary Element Methods. In this context, we examine the impact of geometry upon creation of viscous eddies, fluid flux into the EGL, as well as the role of the EGL in transmitting mechanical signals to the underlying endothelial cells. We then examine electrochemical properties of the EGL by introducing a charge effect into a mathematical model. The asymptotic solutions obtained enable us to investigate some of the important physical phenomena inherent in electroviscous ow in porous media. The results facilitate construction of a numerical technique that allows to simulate a two-dimensional ow through a wavy wall particle-free channel lined with ionised porous material. The data obtained, particularly shear stress exerted on the vessel wall, is of importance for understanding the physiological role of the EGL as a mechanotransducer.

Topic: Hermeneutics and Narrative Identity
Subfield: Philosophy
Field: Arts and Humanities
Domain: Social Sciences
Abstract 2718: Fasting and cancer treatment: A case series

Abstract Short-term fasting (48 hours) was shown to be effective in protecting normal cells and mice but not cancer cells against high dose chemotherapy, termed Differential Stress Resistance (DSR), but the feasibility and effect of fasting in cancer patients undergoing chemotherapy is unknown. Here we describe 10 cases in which patients diagnosed with a variety of malignancies had voluntarily fasted prior to (48-140 hours) and/or following (5-56 hours) chemotherapy. None of these patients, who received an average of 4 cycles of various chemotherapy drugs in combination with fasting, reported significant side effects caused by the fasting itself other than hunger and lightheadedness. Chemotherapy associated toxicity was graded according to the Common Toxicity Criteria (CTC) of the National Cancer Institute (NCI). The six patients who underwent chemotherapy with or without fasting reported a reduction in fatigue, weakness, and gastrointestinal side effects while fasting. In those patients whose cancer progression could be assessed, fasting did not prevent the chemotherapy-induced reduction of tumor volume or tumor markers. Although the 10 cases presented here suggest that fasting in combination with chemotherapy is feasible, safe, and has the potential to ameliorate side effects caused by chemotherapies they are not meant to establish practice guidelines for patients undergoing chemotherapy. Only controlled-randomized clinical trials will determine the effect of fasting on clinical outcomes including quality of life and therapeutic index. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 2010 Apr 17-21; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2010;70(8 Suppl):Abstract nr 2718.

Topic: Dietary Effects on Health
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
[The fossil record of the Eurasian Neogene insectivores (Erinaceomorpha, Soricomorpha, Mammalia) : Part I / L.W. van den Hoek Ostende, C.S. Doukas and J.W.F. Reumer (editors)]: Spain

Introduction Spain, with its many Cenozoic continental basins, has one of the finest fossil records of mammals in the world. The presence of nearly continuous sections with mammal localities make some of these basins ideal for defining mammalian continental stages, such as the Ramblian, Aragonian, Vallesian and Turolian.\nThe first mention of fossils mammals in Spain, and one of the first scientific essays on fossil bones in the world, dates back to the beginning of the eighteenth century, when Benito JerÃ³nimo Feijoo (1736) described the presence of bones near Concud in "El Barranco de las Calaveras" (the valley of the skulls). Feijoo ascribed the numerous bones to a battle in antiquity.\nMore localities were discovered and classical localities like Los Mansuetos were already known early in the history of palaeontology. However, the systematic investigation of the fossil mammals from Spain started in the 1940s. The main driving force was Miquel Crusafont PairÃ³ from Sabadell. Trained as a pharmacist, Crusafont was one of the leading palaeontologists of his days, becoming professor of Paleontology at the University of Barcelona, and founder director of the Institute of Paleontology in Sabadell that took his name after his death on 1983. Together with his co-workers Josep Villalta Comella and Jaume Truyols Santonja, Crusafont published a series of papers on mammals from the VallÃ¨s-PenedÃ¨s area. The fossils they collected formed the basis of the Institute Miquel Crusafont. Crusafont's main field of interest were the carnivores, but

Topic: Evolution and Paleontology Studies
Subfield: Paleontology
Field: Earth and Planetary Sciences
Domain: Physical Sciences
Preferential flows and travel time distributions: defining adequate hypothesis tests for hydrological process models

Abstract This introduction to the second annual review issue of Hydrological Processes tries to put the collection of papers on preferential flows and travel time distributions into a more general context of testing models as hypotheses about how catchment systems function. It is suggested that, because of the possibilities of non‐stationary and epistemic errors in both data and models, such tests could be carried out within a rejectionist limits‐of‐acceptability framework. The principles and difficulties of hypothesis testing within these particular research areas are discussed. An important point to take from this discussion is that the use of a formal testing framework, and the consequent rejection of models as hypotheses after allowing for uncertainties in the data, is the starting point for developing better theories and data sets. Copyright © 2010 John Wiley &amp; Sons, Ltd.

Topic: Hydrology and Watershed Management Studies
Subfield: Water Science and Technology
Field: Environmental Science
Domain: Physical Sciences
Structural insights into the effects of charge-reversal substitutions at the surface of horseradish peroxidase.

Horseradish peroxidase (HRP), has gained significant interests in biotechnology, especially in biosensor field and diagnostic test kits. Hence, its solvent-exposed lysine residues 174, 232, and 241 have been frequently modified with the aim of improving its stability and catalytic efficiency. In this computational study, we investigated the effects of Lys-to-Glu substitutions on HRP structure to model charge-reversal manipulations at the enzyme surface. Simulation results implied that upon these substitutions, the number of stable hydrogen bonds and α-helical content of HRP are increased and the proximal Ca2+ binding pocket becomes more integrated. The results revealed that although Glu174-heme hydrogen bond is lost after mutation, formation of a new hydrogen bonding network contributes to the stability of heme-protein linkage. Together, it may be concluded that these substitutions enhance the stability of the protein moiety as well as the heme-protein non-covalent interactions. In the enzyme active site, we observed increased accessibility of peroxide binding site and heme prosthetic group to the peroxide and aromatic substrates, respectively. Results also demonstrated that the bottleneck entry of the peroxide-binding site has become wider and more flexible upon substitutions. Moreover, the hydrophobic patch functioning as a binding site or trap for reducing aromatic substrates is more extended in mutated enzyme. These observations suggest that the reactivity of the enzyme to its substrates has increased. Together, the results of this simulation study could provide possible structural clues to explain those experimental observations in which the protein stability achieved upon manipulation of charge distribution on protein surface.

Topic: Electrochemical sensors and biosensors
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences