jimnoneill/paper-to-field-training huggingface dataset:
Efficacy of early integrated rehabilitation therapy on treatment outcomes and limb functional recovery in patients with cerebral embolism: An observational study

Cerebral embolism presents a significant challenge for recovery of motor and neurological function. Early integrated rehabilitation therapy (EIRT) has been proposed as a beneficial approach, yet its efficacy requires thorough evaluation. This retrospective study, conducted from January 2020 to January 2023, involved 117 patient’s post-cerebral embolism, divided into an EIRT group (n = 56) receiving EIRT and a control group (n = 61) receiving standard care. The Fugl-Meyer Assessment (FMA) and the National Institutes of Health Stroke Scale (NIHSS) were used to evaluate motor and neurological functions, while muscle strength was categorized from Level 0 (complete paralysis) to Level V (normal strength) to assess physical recovery. Eligibility centered on confirmed cerebral embolism diagnosis, timing of poststroke admission, and baseline functional status. The study adhered to strict ethical standards, with informed consent obtained from all participants. The EIRT group showed substantial improvements in both FMA and NIHSS scores compared to the control group, indicating better motor and neurological recovery. Significant differences were found in the posttreatment FMA ( P &lt; .01) and NIHSS scores ( P &lt; .01). Muscle strength analysis further confirmed the positive impact of EIRT with more patients in the EIRT group achieving higher levels of muscle strength at discharge. The study demonstrates the potential of EIRT to significantly improve motor and neurological outcomes for patient’s post-cerebral embolism. The marked improvements in the observation group suggest that EIRT should be considered for broader application in stroke rehabilitation to enhance recovery and improve quality of life.

Topic: Acute Ischemic Stroke Management
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Crisis de cantidad y calidad en la universidad peruana

Many researchers have described the outgrowing number&amp;nbsp;of universities around our country as a problem: the higher&amp;nbsp;the quantity, the lower the quality and this applies since there&amp;nbsp;are little academic requirements for students to be enrolled.&amp;nbsp;Students have now become sort of "clients". The author&amp;nbsp;deems this situation as an opportunity for the Peruvian higher&amp;nbsp;education, provided that the State and the civil society device&amp;nbsp;mechanisms of requirements and integrate a working plan&amp;nbsp;aiming towards new and productive relationships between&amp;nbsp;the University and the country.

Topic: Magnetic confinement fusion research
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
Supplementary Table 1 from Hedgehog-Producing Cancer Cells Respond to and Require Autocrine Hedgehog Activity

Supplementary Table 1 from Hedgehog-Producing Cancer Cells Respond to and Require Autocrine Hedgehog Activity

Topic: Hedgehog Signaling Pathway Studies
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Assessment of Residual Feed Intake and Its Relevant Measurements in Two Varieties of Japanese Quails (Coturnixcoturnix japonica) under High Environmental Temperature

Three hundred and ten 12-week-old laying Japanese quails (Coturnixcoturnix japonica) from gray and white varieties (155 each) were randomly selected from the initial population and kept in individual battery cages. The measurements of growth and egg production were determined to derive residual feed intake (RFI). The relationship between RFI and egg quality, blood parameters, and carcass characteristics was also determined. The results indicated that the gray quails had significantly higher egg mass and lower broken eggs compared to the white quails. A significant increase of eggshell strength and shell percentage was found in eggs produced from gray quails compared to their white counterparts, although their shell thickness means weresimilar. The results of multiple regression analysis clearly identified a significant effect of metabolic body weight and egg mass for the computation of expected feed intake, rather than body weight gain, in both varieties of Japanese quails. A strong positive correlation between RFI and feed intake in both gray and white quail varieties was found. The same trend was also observed for feed conversion ratio (FCR). Therefore, including RFI in the selection criteria of Japanese quails in order to improve FCR under high environmental temperature is highly recommended.

Topic: Animal Nutrition and Physiology
Subfield: Animal Science and Zoology
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Clonidine suppression test--an evaluation of its diagnostic significance in hypertensive patients.

The Clonidine Suppression Test (CST) was performed in 8 patients with Labile hypertension (Group I), 8 patients with mild and moderate Essential hypertension (Group IIa), 8 patients with severe Essential hypertension (Group IIb) and 6 patients with pheochromocytoma (Group III). The mean plasma catecholamine (CA) levels as estimated by a Spectrofluorimetric method were significantly reduced 3-4 hours after administration of clonidine (5 micrograms/kg) by mouth in Group I, IIa & IIb patients. Plasma norepinephrine levels fell from 1.82 +/- SEM 0.35 ng/ml to 1.03 +/- 0.11 ng/ml (p less than 0.05) in Group I, 1.64 +/- 0.36 ng/ml to 0.88 +/- 0.12 ng/ml (p less than 0.025) in Group IIa, 1.23 +/- 0.16 ng/ml to 0.86 +/- 0.12 ng/ml (p less than 0.005) in Group IIb patients. Plasma epinephrine levels fell from 0.35 +/- 0.06 ng/ml to 0.16 +/- 0.03 ng/ml (p less than 0.05) in Group I, 0.34 +/- 0.04 ng/ml to 0.22 +/- 0.03 ng/ml (p less than 0.01) in Group IIa, 0.33 +/- 0.06 ng/ml to 0.18 +/- 0.03 ng/ml (p less than 0.025) in Group IIb patients. The blood pressure and heart rate showed a similar response. By contrast, in patients with pheochromocytoma, the mean plasma CA levels did not show any significant fall, and even rose during the CST, but, when repeated post-operatively, showed normal suppression. No serious side effects were noticed. We conclude that the CST is a safe and reliable test for the diagnosis of pheochromocytoma.(ABSTRACT TRUNCATED AT 250 WORDS)

Topic: Hormonal Regulation and Hypertension
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
The Origins and Evolution of Humanitarian Action in Southeast Asia

The history of humanitarianism in Southeast Asia is fraught with wicked problems and controversial decisions. Stemming from decades of bloody interstate wars, large-scale natural disasters and protracted subnational conflicts, Southeast Asia continues to be regarded as an especially conflict-ridden and disaster-prone region. This reflects a broader regional trend: a 2008 paper by the United Nations Development Programme identified Asia as having ‘the highest incidence of armed conflicts’ globally, with many lasting for decades and featuring both state-based and non-state-based violence. The ongoing Rohingya refugee crisis in Myanmar, separatist insurgencies in southern Thailand and human trafficking across the Andaman Sea and Bay of Bengal are but a few examples of the panoply of complex humanitarian challenges that come to mind. Even so, as this chapter posits, Southeast Asia’s collective memory is defined as much by acts of violence and political coercion as by humane acts of altruism and moral responsibility. Indeed, the region’s varied cast of humanitarian actors operate at multiple levels (i.e. transnational, domestic, interpersonal) and, depending on their operational context, can be driven by political imperatives as well as principled ideas.

Topic: Religion, Society, and Development
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Kon-Tiki costume

Group of kids dressed as passengers on the raft &amp;quot;Kon-Tiki.&amp;quot; Probably at the Fancy Dress Ball, an annual event held at the Eseeola Lodge at Linville Golf Club in Linville, NC.

Topic: Diptera species taxonomy and behavior
Subfield: Ecology, Evolution, Behavior and Systematics
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Laser damage comparisons of broad-bandwidth, high-reflection optical coatings containing TiO<sub>2</sub>, Nb<sub>2</sub>O<sub>5</sub>, or Ta<sub>2</sub>O<sub>5</sub>high index layers

We develop and characterize high index of refraction thin films by e-beam evaporation of Ti3O5, Ta2O5 and Nb2O5 in reactive, ion-assisted deposition processes. We then deposit broad bandwidth high reflection (HR) coatings based on quarter-wave stacks of these high index layers alternating with SiO2 low index layers. The HR band is centered at 1054 nm and designed for 45o angle of incidence. We compare the laser induced damage thresholds of these coatings in order to explore tradeoffs between their laser damage properties and HR bandwidths.

Topic: Optical Coatings and Gratings
Subfield: Surfaces, Coatings and Films
Field: Materials Science
Domain: Physical Sciences
Some thoughts and reflections on communicative therapy in aphasia

Abstract The author of the leading article deals with a topic very relevant to the general area of discourse performance in aphasia, and the goals which should be established for communicative therapy. Although the author brings up many useful points his argument has a number of serious shortcomings.

Topic: Neurobiology of Language and Bilingualism
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Improving therapeutic effectiveness and safety through big healthcare data

Big healthcare data—electronically recorded longitudinal data generated during the provision and administration of healthcare for millions of patients—have become essential for understanding the effectiveness and safety of therapeutics. They are most effectively used in concert with experimental and laboratory research throughout the life cycle of a drug. Applications range from providing phenotype and health outcomes information in genome‐wide association studies to postmarketing studies that assure prescribers of the safety of approved drugs (Figure ). The uses of big healthcare data and their analysis throughout the life cycle of prescription drugs. image

Topic: Health Systems, Economic Evaluations, Quality of Life
Subfield: Economics and Econometrics
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Surface representations of the three KH domains in the PCBP proteins

<b>Copyright information:</b>Taken from "Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 Å resolution"Nucleic Acids Research 2007;35(8):2651-2660.Published online 10 Apr 2007PMCID:PMC1885661.© 2007 The Author(s) Left: crystal structure of the PCBP2 KH1 domain. Middle: a homologous model (built by the program Modeller based on the crystal structure of PCBP2 KH1) of the PCBP2 KH2 domain. Right: crystal structure of the PCBP2 KH3 domain from the present study. Positively charged, negatively charged, uncharged hydrophilic and hydrophobic residues are colored in blue, red, yellow and green, respectively. Note the large, continuous hydrophobic surface area (in green) of the KH1 and KH2 domains.

Topic: Nuclear Structure and Function
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
&lt;title&gt;LDA measurements of merging flows in a symmetric curved junction model&lt;/title&gt;

A model symmetric junction is used to simulate steady expiratory flow in the upper part of human central airways. Velocity profiles were measured with a two color, two component laser Doppler anemometer at three Reynolds number levels of 518, 1036 and 2089. The test section is a symmetric junction of constant cross-sectional area with a branching angle of 70 degrees. The inlet flow rate into the two bronchi was the same for all Reynolds numbers studied. Results show that in the junction plane, velocity profiles in the bronchi are skewed towards the inner walls. In the trachea, the biconcave shape of the profile (i.e., a dip at the center of the profile) just downstream of the carina is rapidly transformed into a velocity spike. In a plane transverse to the junction plane, parabolic velocity distribution was conserved through the daughter branches. In the parent tube, following merging, the transverse profiles become flat as the flow proceeds downstream of the junction point. Further downstream towards the termination of the trunk of the junction the velocity profile develops a defect at the center. The velocity defect, nonetheless, is confined to a small region only in the vicinity of the centerline. Strong secondary helical motion is chiefly responsible for this type of velocity field in the junction.

Topic: Inhalation and Respiratory Drug Delivery
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Too much delay fault coverage is a bad thing

Delay fault test application via enhanced scan and skewed load techniques is shown to allow scan-based delay tests to be applied that are unrealizable in normal operation. Rather than higher coverage being a positive feature, it is shown to have negative impact on yield and designer productivity. The use of functionally justified tests is defended by both a motivating example and data from benchmark circuits. Implications on overhead, yield, timing optimization, and test debug are discussed.

Topic: VLSI and Analog Circuit Testing
Subfield: Hardware and Architecture
Field: Computer Science
Domain: Physical Sciences
Event Quality, Perceived Value, Destination Image, and Behavioral Intention of Sports Events: The Case of the IAAF World Championship, Daegu, 2011

This study proposes a conceptual model to investigate visitors' perceptions of an event's quality according to value and the destination image, and visitors' resulting behavioral intentions in the context of a mega-sports event. This study also examines whether or not perceived value and destination image determine visitors' future behavioral intentions. Using structural equation modeling analysis, this study determines that an event's quality and its perceived value have a significant effect on behavioral intentions. Moreover, perceived value exerted a direct influence on behavioral intentions, and destination image determined visitors' perceptions of value. However, the impact of destination image had an insignificant effect on behavioral intentions. The implications have merit for academic researchers and sports event organizers.

Topic: Sport and Mega-Event Impacts
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
What Has Artifact Evaluation Ever Done for Us?

Artifact evaluation is an established peer review practice in several fields of computer science research. In the security field it only has been introduced recently. The author highlights several benefits of artifact sharing for and beyond the research community, inspects the specifics of the security field, and derives suggestions to foster artifact sharing in the security field. Embracing artifact sharing will help to strengthen and mature the field.

Topic: Scientific Computing and Data Management
Subfield: Information Systems and Management
Field: Decision Sciences
Domain: Social Sciences
The potential role of YAP in Axl-mediated resistance to EGFR tyrosine kinase inhibitors.

Yes-associated protein (YAP) is a transcription co-regulator downstream of the Hippo pathway, and plays a critical role in cancer. Although YAP regulation in the canonical Hippo pathway is well established, the Hippo-independent regulation of YAP is not well explored. Here, we showed the possible new mechanism of YAP regulation by the receptor tyrosine kinase Axl. Co-immunoprecipitation and Western blot analysis demonstrated the interaction between YAP and Axl, which was enhanced by Axl ligand Growth Arrest Specific 6 (GAS6) stimulation. Furthermore, we found that YAP is phosphorylated at tyrosine residues by GAS6 stimulation <i>in vivo</i> and Axl directly phosphorylates YAP <i>in vitro</i>. Axl overexpression or GAS6 stimulation increased YAP-mediated transcriptional activity, and YAP-mediated colony forming activity in soft agar was enhanced by co-expression of Axl. In EGFR tyrosine kinase inhibitor (TKI)-sensitive lung cancer cells, YAP protein was downregulated in response to TKI treatment, while overexpression of YAP attenuated TKI sensitivity, suggesting that YAP is a key determinant of TKI response. Moreover Axl overexpression reversed TKI-induced YAP downregulation and induced TKI-resistance, which was reversed by YAP knockdown, further supporting the notion that YAP functions downstream of Axl. Together, these findings suggest a novel role of YAP in Axl-mediated TKI resistance.

Topic: Hippo pathway signaling and YAP/TAZ
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
An evaluation of the scales adapted for examining the job demands-resources model in an Indian policing context

The paper aims at documenting an evaluation of Hindi adaption of measurement scales for examining the job demands-resources (JD-R) model - a framework for observing the two facets of work-related well-being (i.e., burnout and work engagement) along with their correlates. Using a cross-sectional design, the study presented the measurement items to 1,600 police officers in an Indian state, Haryana. Exploratory and confirmatory factor analysis assessed the measurement items and scales in terms of dimensionality, reliability, and construct validity. This study findings suggest reliable and valid scales to examine the two (health impairment, and motivational) processes of the JD-R model, with an integration of personal resources in Indian policing context. For the policymakers and particularly for police organisations, the study, a novel one in Indian context, is likely to have important practical implications by offering suitable scales to monitor the work-related well-being along with their correlates.

Topic: Employment and Welfare Studies
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
Topology of graph configuration spaces and quantum statistics

In this thesis we develop a full characterization of abelian quantum statistics on graphs. We explain how the number of anyon phases is related to connectivity. For 2-connected graphs the independence of quantum statistics with respect to the number of particles is proven. For non-planar 3-connected graphs we identify bosons and fermions as the only possible statistics, whereas for planar 3-connected graphs we show that one anyon phase exists. Our approach also yields an alternative proof of the structure theorem for the first homology group of n-particle graph configuration spaces. Finally, we determine the topological gauge potentials for 2-connected graphs. Moreover we present an alternative application of discrete Morse theory for two-particle graph configuration spaces. In contrast to previous constructions, which are based on discrete Morse vector fields, our approach is through Morse functions, which have a nice physical interpretation as two-body potentials constructed from one-body potentials. We also give a brief introduction to discrete Morse theory.

Topic: Topological and Geometric Data Analysis
Subfield: Computational Theory and Mathematics
Field: Computer Science
Domain: Physical Sciences
Clinical implications of cortical microvasculature in adult Moyamoya disease

Objective: Cortical microvascular surface area (MVSA) and arterial microvascular transit time (AMVTT) have been described to be significantly increased in Moyamoya disease (MMD) patients. It was the aim of our study to investigate the clinical implications of anatomic and functional parameters of cortical[for full text, please go to the a.m. URL]

Topic: Moyamoya disease diagnosis and treatment
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
The determinants of point of sales system adoption perceived by micro small medium enterprises in West Java, Indonesia

This paper examines the determinants of a point of sales (POS) system adoption perceived by micro small medium enterprises (MSMEs) by using a cross-section survey data set of the largest population province in Indonesia, West Java. A binary logistic regression is employed to analyse the influence of subjective norms, images, perceived usefulness and perceived ease of use on POS system adoption. Valid and reliable questionnaires are used to collect data. This paper finds that image and perceived usefulness have an impact on the adoption. This result indicates that in the MSMEs context, image and perceived usefulness are factors that have a positive and significant impact on the adopters in terms of functionality.

Topic: SMEs Development and Digital Marketing
Subfield: Demography
Field: Social Sciences
Domain: Social Sciences
A Neutron Dose Calibration by a Low Power Reactor

A few methods for neutron dose measurement have been examined. In this paper, a simple method for dose calibration by a low power reactor is introduced. Calibration with the theoretically calculated values of some neutron dosimeters was made. This calibration was based upon the neutron flux values estimated by the activation method using the neutron field of UTR-B operating at 0.1W. On The calibration with the Bendix fast neutron dosimeter and thermal neutron dosimeters, the experimental values were found to be close enough to the theoritical values to be of practical use from the operational health physics stand point.

Topic: Radiation Therapy and Dosimetry
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Evaluating Cybersecurity Risks of Cooperative Ramp Merging in Mixed Traffic Environments

Connected and automated vehicle (CAV) technology has the potential to greatly improve transportation mobility, safety, and energy efficiency. However, ubiquitous vehicular connectivity also opens up the door to cyberattacks. In this study, we investigate cybersecurity risks of a representative cooperative traffic management application, i.e., highway on-ramp merging, in a mixed traffic environment. We develop threat models with two trajectory spoofing strategies on CAVs to create traffic congestion and devise an attack-resilient strategy for system defense. Furthermore, we leverage VEhicular NeTwork Open Simulator, a Veins extension simulator made for CAV applications, to evaluate cybersecurity risks of the attacks and performance of the proposed defense strategy. A comprehensive case study is conducted across different traffic congestion levels, penetration rates of CAVs, and attack ratios. As expected, the results show that mobility performance decreases up to 55.19% in the worst case when the attack ratio increases, as do safety and energy. With our proposed mitigation defense algorithm, the system's cyberattack resiliency is greatly improved.

Topic: Vehicular Ad Hoc Networks (VANETs)
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
EFFICIENCY OF MANAGEMENT OF FOOD INDUSTRY ENTERPRISES: MANAGEMENT STRATEGY AND ITS ORGANIZATIONAL AND ECONOMIC MECHANISMS

This article discusses the effectiveness of management strategies of food industry enterprises, factors influencing it, ways to increase the competitiveness of enterprises, as well as issues of improving organizational and economic mechanisms of management.

Topic: Economic and Business Development Strategies
Subfield: Economics and Econometrics
Field: Economics, Econometrics and Finance
Domain: Social Sciences