jimnoneill/paper-to-field-training huggingface dataset:
Obstructive Sleep Apnea Surveillance and Oral Appliance Therapy Evaluation, Active Duty US Army, 2014-2019

Study Objectives: Determine the incidence of obstructive sleep apnea (OSA) among United States Army soldiers from 2014 through 2019 and assess self-reported impacts of the disorder and one of its treatments-oral appliance therapy.Methods: Surveillance data were obtained from the Armed Forces Health Surveillance Division; remaining data were self-reported through an electronic survey.Results: There were 87 404 cases of OSA from 2014 through 2019; incidence rates ranged from 274.3 to 330.3 cases per 10 000 personyears (p-yrs).Male incidence rates (from 294.3 to 355.9/10 000 p-yrs) exceeded female incidence rates (from 155.2 to 189.2/10 000 pyrs).Soldiers ≥40 years old had the highest incidence rates (from 820.1 to 973.2/10 000 p-yrs).The survey was completed by 8740 soldiers.The majority reported positive airway pressure therapy as their current treatment method; 9% (n=795) reported treatment with an oral appliance.Comparing pretreatment to post-treatment, respondents treated with the oral appliance reported statistically significant improvements in sleep quality, duration, and various aspects of daily life.The predominance (76%) of those treated with anything other than the oral appliance reported they were not aware of the oral appliance as a treatment method.Conclusion: Results suggest soldiers are satisfied with the oral appliance; it has significantly improved their sleep quality, duration, and various aspects of daily life.Clinical Implications: Military dentists can support a streamlined process to diagnose and treat OSA.The required yearly dental exam provides an opportunity to screen soldiers for OSA and discuss the lesser-known treatment-oral appliance therapy.

Topic: High Altitude and Hypoxia
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Primary ovarian malignant lymphoma presenting as ovarian carcinomatosis: a case report and literature review.

Primary ovarian lymphoma presenting as an ovarian tumor is exceedingly rare. Since the prognosis and treatment of lymphoma differs significantly from ovarian carcinoma, a representative tissue sample of the adnexal tumor should be obtained and sent for frozen section analysis to establish the diagnosis. Principal treatment for non-Hodgkin's lymphoma is chemotherapy without surgical cytoreductive efforts.

Topic: Lymphoma Diagnosis and Treatment
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Energy Dissipation Model for 4G and WLAN Networks in Smart Phones

With the modernization of the telecommunication standards, there has been considerable evolution of various technologies to assist cost effective communication. In this regard, the fourth generation communication services or commonly known as 4G mobile networks have penetrated almost every part of the world to offer faster and seamless data connectivity. However, such services come at the cost of energy drained from the smart phone supporting 4G services. This paper presents an algorithm that is capable of evaluating the actual amount of energy being dissipated while using next generation mobile networks. The study also performs a comparative analysis of energy dissipation of 4G networks with other wireless local area networks to understand the networks that cause more energy dissipation.

Topic: Green IT and Sustainability
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
‘COVID-19: The Fall and Rise of the Events Industry’&#13;\nAn examination of the internal organisational challenges and external&#13;\nindustry transformations in the UK events management sector due to&#13;\ncovid-19 in order to assess the best practices used by professionals and&#13;\nsuggest strategies for preparing and adapting to future unforeseen&#13;\nchallenges

COVID-19 had a devastatingly transformative impact on the UK events industry from&#13;\neverchanging rules and regulations to lockdowns globally. The purpose of this research is to&#13;\ndraw conclusions and recommendations on how organisations in the events industry can&#13;\nimplement strategies to plan for future industry disruptions as well as offering employees an&#13;\nopportunity to reflect on how their job roles have adapted to circumstances to assess best&#13;\npractices.&#13;\nThe research results from a questionnaire using a sample of 16 employees at an experiential&#13;\nmarketing company, Jack Morton London, has been compared with previous literature to&#13;\nunderstand the developments the pandemic forced upon the industry. Through data&#13;\npresentation and discussion, the research has reached conclusions that technology has aided&#13;\nthe events industry through COVID-19 both with innovation through AI and the rise of&#13;\nvirtual/hybrid events, and logistical organisational challenges through virtual meeting software&#13;\nencouraging hybrid working into a post-pandemic environment.&#13;\nAdditionally, the research reveals how the on-going health and safety concerns induced by&#13;\nglobal anxiety surrounding COVID-19 influence consumer decisions, as well as, how pent-up&#13;\ndemand from the pandemic has led to increased demand and popularity for in-person,&#13;\nimmersive experiences. This research is integral to the events industry, as a failure to recognise&#13;\nindustry trends and recognise lessons learned will reult in organisational failure through lack of&#13;\ninnovation.

Topic: Conferences and Exhibitions Management
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
A VALID SELF‐APPRAISAL INSTRUMENT FOR COMMUNITY COLLEGE ADMINISTRATORS

This study resulted from a concern that a valid and reliable self‐assessment instrument was needed for community college administrators. The instrument constructed included thirty performance dimensions. Administrators from three community colleges assisted in the establishment of the validity and reliability of the instrument. The process for developing a self‐assessment instrument for performance appraisal was validated. Implications for practice include a method for administrator self‐improvement of performance and the development of administrator training programs.

Topic: Higher Education Research Studies
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Abstract P256: Epigenetic Changes by Nuclear Calcium/Calmodulin-Dependent Protein Kinase II in the Heart

Calcium is central in the regulation of many cellular functions and alteration of calcium signaling leads to a variety of cardiac disorders. An important question remaining in cardiac biology is how calcium-dependent mechanisms are regulated and more specifically how calcium activates intracellular signaling pathways and regulates gene activity in the cell nucleus. The nuclear isoform of calcium/calmodulin-dependent protein kinase II (CaMKIIB) plays a protective role in the heart under basal conditions, and alteration of its level or activity is associated with pathological events such as cell death and cardiac hypertrophy. We recently made a novel discovery showing that CaMKIIδB couples calcium signals to the genome by targeting specific histones in chromatin. Our preliminary results show that CaMKIIδB selectively phosphorylates histone H3 in vitro and in primary cardiomyocytes. Activation of CaMK activity after α-adrenergic stimulation of primary cardiac cells increases histone H3 phosphorylation at serine 10 (Ser-10), whereas specific elimination of the kinase has the opposite effect. Enhanced phosphorylation of histone H3 Ser-10 is observed in primary fibroblasts and also in primary ventricular myocytes and culminates at 24 hours of stimulation, suggesting that signaling to histone H3 is not limited to highly dividing cells and is not transient. Importantly, Enhanced histone H3 Ser-10 phosphorylation can be detected in the heart of mice subjected to myocardial infarction. These results reveal a new role for CaMK enzymes in chromatin remodeling the heart and that epigenetic changes may contribute to the development cardiac diseases.

Topic: RNA Research and Splicing
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Differences in Pelvic Morphology Between Women with and Without Provoked Vestibulodynia

ABSTRACT Objective Pelvic morphology has been suggested to reflect increased tone and reduced strength of the pelvic floor muscles (PFMs) in women with provoked vestibulodynia (PVD) compared to healthy controls. We aimed to determine whether there are differences in pelvic morphology in the resting state, on maximum voluntary contraction (MVC), or on maximum effort Valsalva maneuver (MVM) between women with and without PVD. Methods While imaged using ultrasound, 38 women with PVD and 39 controls relaxed their PFMs, performed 3 MVCs and performed 3 MVMs. Levator plate length (LPL), levator plate angle (LPA), and anorectal angle (ARA) were determined at rest, at MVC and at MVM. The displacement of the bladder neck (BN) on MVC and on MVM was also determined. Two-way ANCOVAs were used to evaluate the main effects of group and task, the interaction between group and task, and the effect of resting morphology on LPL, LPA, and ARA. A 2-way repeated-measures ANOVA was used to determine whether the groups differed in terms of BN displacement during the tasks. Results Women with PVD had smaller LPLs and LPAs than controls across all tasks. The significant group differences in LPL and LPA at MVC and MVM were no longer significant once the resting values were included as covariates in the models. Bladder neck displacement differed between the groups at MVM but not at MVC. Conclusion Women with PVD display shorter LPL sand smaller LPAs than controls but their behavior does not differ when MVC and MVMs are performed. Our results do not support the hypothesis that women with PVD demonstrate abnormalities in PFM contractility on MVC or compliance on MVM.

Topic: Pelvic floor disorders treatments
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Web based monitoring improves glycaemic control in type 2 diabetes

Research question Can web based enhancements to self monitoring improve glycaemic control for patients with type 2 diabetes? Answer Yes. Glucose monitoring and feedback via the web help reduce concentrations of haemoglobin A(1c) compared with traditional face to face consultations.

Topic: Diabetes Management and Research
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Some Factors in the Decline of the Osprey in Connecticut

THE Osprey (Pandion haliaetus) is an inviting subject for ecological study, with its exposed and often gregarious nesting, and its conspicuous feeding behavior. In many parts of the world the Osprey nests in loose colonies of a few to several hundred pairs. One of the best-known colonies in the northeastern United States is at the eastern end of Long Island Sound in coastal Connecticut and New York. The birds on Gardiners Island, New York, have been studied by many people, principally by LeRoy Wilcox, who has banded nestlings for more than 20 years. Until our study started, in 1957, the Ospreys on the Connecticut shore of the Sound had never been studied ecologically. Our goal, to evaluate population-regulating factors and other aspects of breeding ecology, has been only partially attained, but our tentative conclusions may prove of use to others studying the ecology of birds of prey.

Topic: Avian ecology and behavior
Subfield: Ecology
Field: Environmental Science
Domain: Physical Sciences
Motivations for Social Interaction: The Case of Pokémon Go After the Fad Ended

Objective We survey Pokémon Go players regarding motivations/patterns of gameplay and sociability over time to understand human interaction in augmented game settings. We disentangle effects of solo versus social and past versus current gameplay through replication of the Pokémon Go Motive Scale. Methods We use OLS regression to determine how motivation affects hours of gameplay, to measure changes in hours spent playing Pokémon Go, and to capture perceptions of engagement with the game over time. Results We find seven motivations: exercise, fun, escapism, nostalgia, friendship maintenance, relationship initiation, and achievement. Initiating new relationships leads to increased social playing time and increased perceptions of Pokémon Go as both interesting and challenging. Conclusion Intrinsic rewards hold the most staying power as a distinct motivation for gameplay. Implications go beyond Pokemon Go gaming to shed light on the differential impact of human motivation for social interaction in games that utilize augmented reality.

Topic: Media Influence and Health
Subfield: Literature and Literary Theory
Field: Arts and Humanities
Domain: Social Sciences
Villous Adenoma of the Rectosigmoid and Sigmoid Colon

Villous adenoma of the colon is an interesting and unique tumor. It has been referred to by many names, including papillary adenoma or polyp; villous papillary adenoma; villous, columnar, or mucous papilloma; papilloma; villoma and villous tumor. Although numerous reports of this neoplasm have been published, few of them have appeared in the radiological literature (6), and little emphasis has been placed upon the roentgen diagnosis (26). X-ray studies after a barium enema have been said by some authors (1) not to be helpful in most cases. The reason may be that the majority of villous adenomas, approximately 80 per cent (25), are located in the rectum and rectosigmoid and are accessible for diagnosis and treatment by sigmoidoscopy (10, 11). Nevertheless, a roentgen study of the colon is an indispensable aid in the diagnosis of these tumors, regardless of location. Radiologically, the limits of the neoplasm can be ascertained, and additional lesions, either benign or malignant, may be demonstrated in approximately one-third of the cases (25). This report of 2 cases is submitted because of certain radiographic characteristics depicted by air-contrast study, which, when correlated with the clinical findings, resulted in an accurate roentgen diagnosis in the second case. Clinical Manifestations Renewed interest in villous adenoma has been shown during the past few years due to the recognition of a definite clinical syndrome, characterized by excessive mucus (pseudodiarrhea), rectal bleeding, and severe electrolyte depletion (3, 5, 6, 12–15, 17–19, 21–24). The electrolytes which are affected are particularly sodium and potassium. Not all patients with villous tumors show fluid and electrolyte imbalance (2, 8, 11, 22); when present, it is a late complication (19, 26) leading to death in some cases (7, 15, 18). This syndrome was apparently first recognized by McKittrick and Wheelock (16). The salient symptomatology consists of an excessive watery mucous type of secretion, rectal bleeding, and occasional tenesmus. Characteristically, the patient passes a considerable amount of mucus upon arising in the morning. This may be preceded or followed by a normal bowel movement. Secretion and expulsion of mucus continue thereafter, from five to twenty times a day (19). This is described by the patient as a “diarrhea,” but close questioning will reveal the true nature of the discharge. The patient should be asked specifically to describe the character of the “diarrhea” stools. Only when they are numerous, clear, and watery is suspicion of villous adenoma aroused. Villous tumors are found more commonly in the fifth and sixth decades of life, in either sex (2, 22); they are seldom encountered before forty years of age (20). The reported incidence of benign villous tumors varies from 2 to 8 per cent of adenomas of the colon (2, 8) and does not exceed 3 per cent of all tumors of the large bowel (9).

Topic: Colorectal and Anal Carcinomas
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Indications and limits of digital tomosynthesis in trauma imaging.

Poster: ECR 2015 / C-1788 / Indications and limits of digital tomosynthesis in trauma imaging.   by: P. Gollini, G. Battezzati, G. Cortese; Torino/IT

Topic: Advanced X-ray and CT Imaging
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
The Ketibiqere in the Aramaic Portions of Ezra and Daniel

language represented by the Tiberian vowel points in the biblical text (Q). By way of contrast, most previous work on the date and provenance of BA has concentrated on the consonantal text (K).1 At an earlier date, scholars studying the question of dialects in Ezra and Daniel drew mainly on Old Aramaic (OA) texts which come from the 8th-5th centuries B.C.E. or on Egyptian Aramaic, socalled Imperial or Official Aramaic (OfA). Currently, the outcome of this research is to suggest that the Aramaic of K in both Ezra and Daniel antedates the emergence of Middle Aramaic dialects with distinctive Western or Eastern features. The K appears to belong to the stratum of OfA, albeit, in the case of Daniel it may belong to the very end of that period.2 Opinions vary regarding the identity of the Q with the Aramaic represented in the K. Although it is often assumed that the language represented in the vocalization of BA antedates the language of targumic Aramaic and cognate literature3 at the present time the linguistic provenance and character of the Q remains

Topic: Historical and Linguistic Studies
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Direct observation of the Ni stabilising effect in interfacial (Cu,Ni)6Sn5 intermetallic compounds

The polymorphic transformation in interfacial intermetallic compounds in three lead-free solder joints was investigated using in situ heating/isothermal/cooling observation techniques in high-voltage transmission electron microscopy (HVTEM). Here, the hexagonal η- to monoclinic η′-Cu6Sn5 polymorphic transformation was visualised systematically through zone-axis electron diffraction patterns and real-space imaging. Cu6Sn5 grains obtained in the as-reflowed solder joints that did not contain Ni (Sn–0.7Cu/Cu and Sn–3.0Ag–0.5Cu/Cu) show weak reflections in the diffraction patterns from the η′-Cu6Sn5. In Sn–0.7Cu–0.05Ni/Cu joints, no weak reflections were present in the diffraction patterns of the (Cu,Ni)6Sn5 grains indicating the presence of Ni prevented the η- to η′-Cu6Sn5 transformation. The movement of bend contours was also observed at around 186 °C in adjacent the grain boundaries in Cu6Sn5 but not in the (Cu,Ni)6Sn5. We also uncover the origin of the weak reflections and confirm the superstructure of monoclinic η′-Cu6Sn5 by obtaining atomic-resolution images within the areas from which the selected area diffraction patterns were obtained.

Topic: Electronic Packaging and Soldering Technologies
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Gymnotus cylindricus: Lyons, T.J. &amp; Matamoros, W.A.

Established in 1964, the IUCN Red List of Threatened Species has evolved to become the world’s most comprehensive information source on the global conservation status of animal, fungi and plant species.

Topic: Mediterranean and Iberian flora and fauna
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
SURVEY TESTS. EMISSIONS FROM A VOLVO BUS WITH A TD 123 ES ENGINE AND FROM FOUR PREVIOUSLY REPORTED HD VEHICLES

In a survey test series two buses, two trucks and one light duty truck have been tested regarding exhaust emissions. Four of the have previously been reported in MTC 9406A. These four vehicles are: a Scania city bus with a DSC 1127 engine, a Volvo Truck with a TD 63 ES engine, a Mercedes Benz 814 truck with an OM 366 engine and a Tristar truck with a Ford 250 Tristar engine. Now, a Volvo bus with a TD 123 ES engine has been tested. The tests were carried out on a chassis dynamometer. Test cycles were the A30 Regulation test, simulated on the chassis dynamometer, US transient cycle for heavy duty vehicles and the Braunschweig bus cycle. The tested vehicles have modern engines. The emissions at the simulated A30 tests were within the limits of the certification tests. The Scania bus was noise tested and did not pass the requirements for the noise emission of C1. The buses and the Mercedes Benz truck were tested twice. At the first time the Scania bus was new, at the second time, about 1,5 years later, the odometer reading was 142 000 km. The NOx emission increased somewhat at simulated A30 Regulation tests. The CO and HC emissions showed changes due to catalyst deterioration, but were still low. The odometer reading of the Mercedes Benz truck was 13 700 km at the first test occasion and at the second 76 200 km. The emission changes were small or insignificant. The odometer reading of the Volvo bus was 222 000 km at the first test occasion and at the second time 300 100 km. No significant emission changes were observed at the steady state tests. At the transient driving cycles CO and particulate emissions had increased. (A)

Topic: Vehicle emissions and performance
Subfield: Automotive Engineering
Field: Engineering
Domain: Physical Sciences
Genetic variations in cytarabine pathway genes as determinants of outcome in acute myeloid leukemia.

10005 Background: Cytarabine (ara-C), a key component of AML therapy, is a prodrug that requires activation to ara-CTP, which inhibits DNA/RNA synthesis and triggers leukemic cell death. Thus, cellular pathways involved in ara-CTP metabolism and/or cell death are likely to influence treatment response. Methods: In the present study, we used a pathway-directed approach to identify the genetic predictors of ara-C response in 187 pediatric patients enrolled in the St. Jude AML02 trial. Patients were randomized to receive the first course of remission induction therapy containing either high- or low-dose ara-C, combined with daunorubicin and etoposide. SNPs in 14 key ara-C pathway genes were genotyped and screened for association with multiple endpoints, such as in vitro ara-C LC50 in diagnostic leukemic cells, minimal residual disease levels (MRD), event-free survival (EFS), overall survival (OS), and rate of relapse. Because AML is a very heterogeneous disease with multiple clinical, cytogenetic, and molecular features that are associated with response, we also evaluated SNPs in ara-C PK genes in the context of prognostic factors of proven clinical utility. Results: Ara-C pathway SNPs were significantly associated with clinical outcome. Known variables such as treatment, core-binding factor leukemia, MRD after one course of therapy, age at diagnosis, 11q23 rearrangements, megakaryoblastic leukemia without t(1;22), and FLT3-ITD accounted for 18.7% of variability in EFS. Additional variation in EFS could be explained by individual SNPs or a combination of SNPs within ara-C pathway genes. For instance, our analysis showed that incorporation of a DCTD SNP into existing model could enhance the percent total variation in EFS explained from 18.7% to 22.9%. Inclusion of all DCTD SNPs in the model increased the percent total variation in EFS explained from 18.7% to 29.7% Conclusions: Overall our results indicate that genetic variation in the ara-C pathway genes had a prognostic relevance that was similar to that of well-known factors. Understanding this variation can provide additional insights into the factors influencing treatment response and could lead to the identification of new prognostic markers.

Topic: Acute Myeloid Leukemia Research
Subfield: Hematology
Field: Medicine
Domain: Health Sciences