jimnoneill/paper-to-field-training huggingface dataset:
The Mechanism of Aminoacylation of Yeast Phenylalanine Transfer Ribonucleic Acid

Conference Article| December 01 1975 The Mechanism of Aminoacylation of Yeast Phenylalanine Transfer Ribonucleic Acid RAINER THIEBE RAINER THIEBE 1Institut für Physiologische Chemie, Physikalische Biochemie und Zellbiologie der Universität München, D-9 München 2, Goethestrasse 33, West Germany Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1975) 3 (6): 907. https://doi.org/10.1042/bst0030907 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation RAINER THIEBE; The Mechanism of Aminoacylation of Yeast Phenylalanine Transfer Ribonucleic Acid. Biochem Soc Trans 1 December 1975; 3 (6): 907. doi: https://doi.org/10.1042/bst0030907 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1975 Biochemical Society1975 Article PDF first page preview Close Modal You do not currently have access to this content.

Topic: DNA and Nucleic Acid Chemistry
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Coevolution of black holes and host galaxies

One of the most important astronomical discoveries of the last 20 years is that most local massive galaxies host a supermassive black hole (hereafter BH), with mass of ∼ 10^6 − 10^10 solar masses , in their centre. The most relevant discovery supporting a connection between a BH and its host galaxy is the tight correlation between the BH mass and the velocity dispersion of the stars in the bulge, which corresponds to the whole galaxy for the elliptical ones. Together with similar correlations with bulge luminosity and mass, this led to the belief that BHs and bulges coevolve by regulating each other’s growth. However, the difference of nine orders of magnitude between the typical spatial scales of BHs and bulges seems to preclude a direct casual connection.The goal of this thesis is a comprehensive investigation of the BH-galaxy coevolution over cosmic time and, in particular, of the main processes connecting a BH to its host galaxy. To analyse the evolution of star-forming galaxies over the cosmic history, we made use of data obtained at different wavelength ranges thanks to the new generation telescopes, such as the astronomical interferometry Atacama Large Millimetre/submillimetre Array (ALMA).

Topic: Mathematical and Theoretical Analysis
Subfield: Mathematical Physics
Field: Mathematics
Domain: Physical Sciences
Thyroid-stimulating immunoglobulins in neonatal Graves's disease.

Two patients with neonatal Graves's disease are reported. One of them had a delayed onset because of suppression of the fetal thyroid gland by antithyroid drug taken by the mother during pregnancy. Thyroid-stimulating immunoglobulins (TSAb), measured by a receptor assay, were present in both babies when they were thyrotoxic, and also in their mothers. TSAb were undetectable in both babies 1 year after birth. This strongly supports a pathogenetic role of TSAb in this condition through transplacental transfer of maternal TSAb.

Topic: Thyroid Disorders and Treatments
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
The Neolithic Causewayed Enclosure at Staines, Surrey: Excavations 1961–63

The partial excavation under rescue conditions in 1961–63 of the ditches and interior of an enclosure of the earlier neolithic period is described. The enclosure, covering a total area of approximately 2.4 ha, was defined by double concentric interrupted ditches, which were for the most part naturally filled. There were many traces of activity within the interior, presumed to be contemporary with the ditches, including pits, gullies, post- and stake-holes, and varying concentrations of struck and burnt flint and pottery. Human burials were found. There is a little Ebbsfleet pottery in secondary contexts and there are later prehistoric, Roman and medieval finds. It is probably not possible to ascribe a single or specific role to the site, which may have been important as a place where several activities were concentrated, including occupation, subsistence, exchange, enclosure or defence, burial and ritual.

Topic: Forensic Anthropology and Bioarchaeology Studies
Subfield: Archeology
Field: Arts and Humanities
Domain: Social Sciences
Successful Treatment with Patisiran in Amyloid Polyneuropathy Harboring His90Asn Mutation in the TTR Gene

Hereditary transthyretin amyloidosis (hATTR) is a multisystemic, rare, inherited, progressive and adult-onset disease, affecting the sensory-motor nerves, heart, autonomic function, and other organs. There are over 130 mutations known in the TTR gene. The His90Asn mutation has been previously reported in several reports, but its pathogenetic role is still debated. We report two sporadic cases of adult women with a heterozygous His90Asn mutation in TTR gene and neurological involvement extensively investigated. A typical Congo red-positive pathologic deposition of amyloid fibrils in the salivary glands was documented in one subject. Patients were successfully treated with patisiran with a good clinical outcome. These data support a pathogenetic role of His90Asn mutation in hATTR, and suggest early treatment in symptomatic carriers of His90Asn mutation.

Topic: Amyloidosis: Diagnosis, Treatment, Outcomes
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
The public visibility of Islam and European politics of resentment: The minarets-mosques debate

The public visibility of Islam reveals new political stakes in European democracies around issues of immigration and citizenship. By focusing on the societal debates and the controversies around the construction of mosques and minarets, this article explores the ways in which Islamic difference is manifested, perceived and framed in public life. The ‘visibility’ of Islam in public is conceptualized as a form of agency, a manifestation of religious difference that cannot be thought independent of the materiality of culture, namely aesthetic forms, dress codes, or architectural genres. It is argued that the debates for or against the banning of the construction of mosques and/or minarets reveal the tumultuous transition of Muslims from the status of the invisible migrant-worker to that of visible Muslim citizenship. The public visibility is approached therefore as a radically disruptive, transgressive, provocative form of transformative agency that is intrinsically related to the political process of becoming citizens.

Topic: Terrorism, Counterterrorism, and Political Violence
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
The Irrelevance of Active Poison Pills: Evidence from a Natural Experiment

I use a novel, hand coded dataset with pill-related information for a large sample of large firms over the period 2000/2011 to analyze how having an active poison pill affects firm value and operating performance. I exploit a change in the voting guidelines of Institutional Shareholder Services as a source of exogenous variation in the extent to which firms have an active poison pill in place. I conclude that, contrary to what one may believe by using a simpler identification strategy, there is no evidence that having an active pill in place has any effect on firm value or operating performance.

Topic: Corporate Finance and Governance
Subfield: Accounting
Field: Business, Management and Accounting
Domain: Social Sciences
Evaluation of Security Mechanisms for Information Dissemination in Wireless Sensor Networks

In recent years, extensive research has been conducted on Wireless Sensor Networks (WSNs) due to their wide range of potential applications ranging from commercial to critical military and health care applications. For most of these applications, security is an important requirement. However, security mechanisms in WSNs differ from traditional ad-hoc networks due to their energy and resource constraints. Due to these constraints, the sensor nodes are vulnerable to security threats because the traditional security measures are not enough to protect these nodes during information dissemination in WSNs. Thus, in this paper we have studied TinySec security measures, Authentication-only (TinySec-Auth) and Authentication Encryption (TinySec-AE) in order to evaluate the suitability of these security measures for WSN applications. We have evaluated these TinySec mechanisms in terms of packet transmission time, average number of packet received and energy consumption. The simulation results show that TinySec-AE consumed more energy and required more time to transmit packet in comparing to TinySec-Auth due to higher computational time and longer packet size for extra encryption mechanism.

Topic: Security in Wireless Sensor Networks
Subfield: Computer Networks and Communications
Field: Computer Science
Domain: Physical Sciences
Justice, management, and governance

Purpose The object of this paper is to examine the debate in business ethics over extending insights from political philosophy (e.g. theories of distributive justice) to address questions about the management and governance of economic enterprises. Design/methodology/approach The paper engages in a philosophical argument. Findings Even if justice does not matter in a direct manner for questions about economic enterprises, current debate overlooks the possibility that justice matters in an indirect manner for questions about the management and governance of economic enterprises. The paper illustrates two ways in which justice matters for such questions. The first concerns the promotion of stakeholder interests by multinational corporations. The second concerns the claims of workers to participate in the governance of economic enterprises. Originality/value The paper is offered as a contribution to the literature on normative theories of managerial responsibility and corporate governance.

Topic: Ethics in Business and Education
Subfield: Information Systems and Management
Field: Decision Sciences
Domain: Social Sciences
HYDROPERICARDIUM HEPATITIS SYNDROME AND VACCINATION WITH INFECTED LIVER EXTRACT

The experiment was carried out to evaluate a killed vaccine of HHS prepared from liver extract treated with (0.1%) formalin . The vaccine was injected Sc. Or. im. At (12) or (12,20) days old broilers . At age of 25 days, chicks were challenged with HHS liver extract . The vaccinated chicks showed full protection with no clinical signs or pathological changes .

Topic: Liver Disease Diagnosis and Treatment
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Design and Implementation of Iterative Algorithm in Auto-Arrange Curriculum System

On the basis of comprehensive analysis about the functions and data flow of collegial educational administration system, a detail description of the database design on curriculum arrangement system is given in this article, and the iterative algorithm for auto-arranging curriculum is presented to determine the classroom that meets the course conditions and to arrange concrete class-time according to courses information and classroom resource by the circulative iteration. The function of auto-arranging curriculum is realized.

Topic: Educational Technology and Assessment
Subfield: Information Systems
Field: Computer Science
Domain: Physical Sciences
Plain and Reinforced Concrete Targets Subjected to Projectile Impact

The ballistic performance of plain concrete and reinforced concrete targets of unconfined compressive strength 40 MPa was studied against projectile impact. The squarer plates of (450 mm x 450 mm) and thickness 60 mm with and without (8 [email protected] mmc/c) reinforcement were subjected to normal impact of hardened steel ogive nosed projectiles with diameter 19 mm and mass 0.5 kg. The incident velocities of the projectiles were varied between 28 to 102 m/s. The amount and area of damage, volume of spalling and scabbing as well as the ballistic limit of plain and reinforced concrete have been obtained and their results have been compared and discussed. The influence of reinforcement is clearly visible in minimizing the scabbing and spalling of material. The magnitude of scabbing decreased with increase in the projectile incidence velocity while the spalling of material remained unaffected. The ballistic limit of reinforced concrete target was 20% higher than plain concrete target for 60 mm thickness.

Topic: High-Velocity Impact and Material Behavior
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Practice of European Court of Human Rights (ECHR) in the enforcement of courtsï¿½ final decisions

The paper aims at highlighting the importance of enforcement of judicial decisions as a key factor in building Rule of Law. As courts do not have the opportunity to lead themselves the process of decisionsï¿½s execution and the respective institutions have performed poor results, many cases are presented in front of European Court of Human Rights due to the lack of efficiency in executing judicial decisions. Obtaining a favorable judicial decision does not imply necessarily the fulfillment of the general purpose, and ECHR through itï¿½s judgements has argued that the right to proper administration of justice implies that the enforcement of court decisions should itself be effective and efficient. Being considered as a compulsory provision for the successful conclusion of a legal process, the enforcment of courtsï¿½ final decisions within a reasonable time is an essential element of a fair trial. Also, this paper analyses the circumstances when excuses such as case complexity or lack of funds are considered objective and what is the responsibility of the states toward organizing their judicial system so that the justice is awarded.

Topic: European and International Law Studies
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
The role of “Bank of Kimchi Resources and Information”, biological resources integrated Information platform of kimchi

Modern society is in the era of the bio economy, and it is predicted that the value of bio materials will become more prominent in the future. In particular, the necessity and importance of national sovereignty over biological resources is emphasized with the adoption of the Protocol on Access and Benefit Sharing of Biological Resources for the purpose of the Convention on Biological Diversity (2010). The importance of securing differentiated biological resources and information as source materials for the bio industry is increasing. As a research institute leading kimchi R&D, the World Institute of Kimchi strives to scientifically prove the excellence of kimchi, and the results of its efforts are systematically compiled in the "Bank of Kimchi Resources and Information (BKRI)." In this article, an efficient information system is introduced, from the acquisition, storage, and distribution system of physical resources integrated and managed by BKRI to the disclosure of information resources.

Topic: Food Quality and Safety Studies
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
A review of the diatom research in the Gulf of Gdańsk and Vistula Lagoon (southern Baltic Sea)

Abstract The paper presents the history of diatom studies carried out in the Gulf of Gdańsk and the Vistula Lagoon since the beginning of the 20th century. One aspect of the research focuses on describing the structure of planktonic and benthic communities living in different parts of the area or occurring in their surface sediments as taphocoenoses. Other investigations concentrate on the fossil diatom flora, which is widely used in the research on the Late Glacial and Holocene to resolve paleogeographic, sedimentological and paleoecological problems.

Topic: Diatoms and Algae Research
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Multiple model based adaptive control of a DC motor under load changes

This short paper aims to survey available multiple model adaptive control (MMAC) techniques and to propose a different methodology for the multiple model based approach for the control of a DC motor under load changes. Two general approaches in MMAC, namely, multiple fixed models and multiple adaptive models have been reviewed and a novel method, which is based on the linear combination of adaptive models with no switching, is proposed. The proposed method is tested for the servo control of a DC motor. Performance of classical indirect adaptive control, MMAC methods and the proposed methodology is compared under abrupt large parameter changes.

Topic: Iterative Learning Control Systems
Subfield: Control and Systems Engineering
Field: Engineering
Domain: Physical Sciences
Physical Science Study Committee

The newly formed Physical Science Study Committee, directed by Jerrold R. Zacharias, Elbert P. Little, and Francis L. Friedman, held its first major planning conference on December 10, 11, and 12, 1956, at the Massachusetts Institute of Technology. The committee met to discuss and plan improved and modernized courses in physical science for secondary schools, under a program sponsored by the National Science Foundation. In attendance were forty-eight committee members, representing more than a dozen universities, government agencies, and commercial laboratories.

Topic: Science and Science Education
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
Child Maltreatment Profiles of Finnish Parents and Their Association With Parental Burnout During COVID-19-Lockdown

Although it has been proposed that the COVID-19 pandemic has increased the risk of parental burnout and child maltreatment in families, parent-reported empirical evidence is scarce. Furthermore, it is unknown whether different profiles of maltreatment can be identified among parents based on physical violence, emotional violence, and neglect, and how these profiles differ based on family-related background variables. We adopted a person-oriented approach and examined maltreatment profiles of Finnish parents and their association with parental burnout and different background variables. The participants were 967 Finnish parents (88% mothers) who filled in a questionnaire during the COVID-19 lockdown in the Spring of 2020. The data were analyzed using k-means cluster analysis, one-way analysis of variance (ANOVA), chi-square test, Kruskal–Wallis test, and multinominal regression. We found four different profiles: no maltreatment (67.4%), emotional maltreatment (21.3%), neglectful maltreatment (7.3%), and diverse maltreatment (3.9%). Parental burnout was associated with all maltreatment profiles. Furthermore, parents’ low education level as well as children's young age and the high number of boys in the family were associated with maltreatment profiles. More than one third of the parents used some form of maltreatment during the COVID lockdown, emotional maltreatment being the most common profile. From a prevention point of view, it is important to identify those parents who are at risk for burnout and offer early educational and practical support particularly for families with young children.

Topic: Child Abuse and Trauma
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Integrating an innovative social work practice into a pediatric dental residency program

Summary This article describes the implementation and outcomes of a social work program in a university pediatric dental clinic serving low-income families. The goal was to decrease barriers to dental care access, decrease appointment failure, and improve interprofessional practice (IPP). Funding was obtained through a foundation to hire a social worker and two interns, and cover program costs. A survey identified barriers families faced to obtain and complete pediatric dental care. Residents, dental students, and faculty make referrals to the social workers who intervene to help families overcome challenges for their children's care. Findings The program started in January 2019 and outcomes are reported through June 2021. The largest barriers families identified were lack of a pediatric dentist near home accepting public insurance (91%), the dentist who saw their child only did exams and cleanings but not fillings (84%), and need for specialized dental care (77%). Five hundred and eleven families were referred to the social workers, most commonly for resources, information or other referrals (30.5%), dental insurance lapse (14.9%), caregiver guidance on oral health (10.6%), mental health concerns (10.4%), and poor treatment compliance (9.6%). Social workers provided 424 interventions, mostly about information regarding community resources (26.8%), transportation issues (15.9%), and telephone consults (14.2%). Appointment failure rates decreased from 17% to 13.5%, while the cancelation rate decreased from 19.2% to 14.3% from January 2019 to June 2021, respectively. Applications Social workers helped decrease barriers to pediatric dental care, improve attendance to dental appointments, and enhance IPP for pediatric dental residents, students, and faculty.

Topic: Dental Health and Care Utilization
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Improved RawNet with Feature Map Scaling for Text-Independent Speaker Verification Using Raw Waveforms

Recent advances in deep learning have facilitated the design of speaker verification systems that directly input raw waveforms.For example, RawNet [1] extracts speaker embeddings from raw waveforms, which simplifies the process pipeline and demonstrates competitive performance.In this study, we improve RawNet by scaling feature maps using various methods.The proposed mechanism utilizes a scale vector that adopts a sigmoid non-linear function.It refers to a vector with dimensionality equal to the number of filters in a given feature map.Using a scale vector, we propose to scale the feature map multiplicatively, additively, or both.In addition, we investigate replacing the first convolution layer with the sinc-convolution layer of SincNet.Experiments performed on the VoxCeleb1 evaluation dataset demonstrate the effectiveness of the proposed methods, and the best performing system reduces the equal error rate by half compared to the original RawNet.Expanded evaluation results obtained using the VoxCeleb1-E and VoxCeleb-H protocols marginally outperform existing state-ofthe-art systems.

Topic: Speech Recognition and Synthesis
Subfield: Artificial Intelligence
Field: Computer Science
Domain: Physical Sciences
Pushing the Envelope for Evolution and Social Change

The Inside-Out Prison Exchange Program (Inside-Out) is a program that offers college courses taught in a blended classroom within correctional settings, resulting in multiple challenges for instructors. This article focuses on three major challenges that should be considered by Inside-Out instructors: addressing legal challenges for the instructor, students, university, and prison site; creating and sustaining diversity in a blended classroom; and, balancing the rules of the Inside-Out program and the institution. Utilizing a post hoc observation-as-participant framework, we present our experiences of teaching Inside-Out courses to demonstrate these distinct challenges and provide recommendations for current and future Inside-Out faculty, as well as the National program.

Topic: Criminal Justice and Corrections Analysis
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences