jimnoneill/paper-to-field-training huggingface dataset:
Development of Blockchain-Based Digital Signature Platform

As technology develops, the Internet of Things (IOT) becomes a topic that is being mentioned over and over again. Many things can be done online. One of them is document signing activity. A company named “XYZ” wanted to build a prototype application using a framework that can build and develop a multiplatform app that can be used to sign a document and secure it with digital certificates, and the transaction activity is recorded and can be verified through a blockchain system. This study aims to find out how to apply blockchain system in a series of digital signing activities, how are the concept and how to verify a transaction that already recorded in a blockchain system, and also how to make a prototype that easy to develop further for other platforms. In the end, the application can be made easily using Expo, Node.Js, and the process for recording and verifying transactions can be done easily with the help of Hyperledger Iroha.

Topic: Blockchain Technology in Education and Learning
Subfield: Information Systems
Field: Computer Science
Domain: Physical Sciences
Effects of recovery type after a judo combat on blood lactate removal and on performance in an intermittent anaerobic task.

The ability to maintain power output during intermittent anaerobic exercises can discriminate properly judo players of different levels. Lactate removal was improved with AR when compared to PR but AR did not improve performance in a subsequent intermittent anaerobic exercise.

Topic: Sports Performance and Training
Subfield: Orthopedics and Sports Medicine
Field: Medicine
Domain: Health Sciences
Numerical Simulations of Blood Flow in a Stenosed Vessel under Different Flow Rates using a Generalized Oldroyd-B Model

The present paper discusses the influence and importance of the application of generalized Newtonian and generalized viscoelastic models to blood flow simulations. A simple shear‐thinning viscosity model together with a Oldroyd‐B model for the viscoelastic part of the stress was applied to a simplified test case of stenosed vessel. The direct comparison between results of Newtonian and non‐Newtonian flows is presented for various flow rates. The aim of the study is to test the applicability of the presented numerical method to this type of flows.

Topic: Coronary Interventions and Diagnostics
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
PMA suppresses breast cancer cell proliferation via PKCε‐mediated P‐Rex1 downregulation (1148.5)

Upregulated phosphatidylinositol‐3,4,5‐trisphosphate‐dependent Rac exchange factor 1 (P‐Rex1) promotes tumorigenesis and metastasis of various cancers, and thus could be a potential therapeutic target. The present study was to investigate the role and mechanism underlying phorbol‐12‐myristate‐13‐acetate (PMA), a protein kinase C (PKC) activator, down‐regulation of P‐Rex1 in breast cancer cells. Western blot analysis showed that PMA treatment caused a time‐ and concentration‐dependent decrease in P‐Rex1 protein levels in breast cancer MCF‐7 and BT‐474 cells with a maximum reduction of 87.2 ± 1.1 and 57.0 ± 8.6 %, respectively, at a concentration of 10 ng/ml. Interestingly, either silence of P‐Rex1 by siRNA or PMA treatment inhibits breast cancer cell proliferation by over 70%, which can be attenuated by restoring P‐Rex1 expression. MCF‐7 cells express PMA‐sensitive PKCα, δ, ε, and η. The PKC general inhibitor Gö6983, but not the PKCα‐selective inhibitor Gö6976, blocked the PMA down‐regulation of P‐Rex1 expression and breast cancer cell proliferation. Overexpression of a constitutively active PKCε mutant suppressed P‐Rex1 expression and breast cancer cell proliferation, which was also blocked by Gö6983 treatment. In contrast, overexpression of wild‐type PKCε, wild‐type or constitutively active PKCδ and PKCη had no effect. Together, our data suggest that PMA suppresses breast cancer cell proliferation via PKCε‐mediated P‐Rex1 down‐regulation. Since P‐Rex1 is highly overexpressed in human breast cancers with estrogen receptor (ER) expression, our study may provide a novel strategy for development of chemotherapeutic agents for patients with ER positive tumors that develop resistance to anti‐estrogen therapies. Grant Funding Source : Supported by the National Institutes of Health (CA125661 and 5P20GM103489) and Nebraska State LB595

Topic: PI3K/AKT/mTOR signaling in cancer
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Secondary Synchronization Signal in 5G New Radio

We propose a secondary synchronization signal (SSS) for the fifth generation (5G) New Radio (NR) communication systems, which is based on the element-wise multiplication of two BPSK modulated m-sequences with different cyclic shifts encoding the physical cell identity (ID) carried by the NR SSS. We present the details on the generator polynomial selection for the involved m-sequences and the mapping between their cyclic shift values and the cell ID. We also propose a double- threshold detection method which is able to mitigate false cell ID detection. Simulation results are provided to demonstrate the superiority of the proposed NR SSS over the LTE SSS. The proposed NR SSS has been accepted in 3GPP Release 15 technical specification.

Topic: Advanced Wireless Communication Techniques
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Multiple Upsets Induced by Protons in 90-nm SRAMs

The occurrence of single-event upsets (SEUs) in 90-nm SRAM integrated circuits irradiated by 1000-MeV protons has been investigated. The experimental data were analyzed and processed, and the results showed the possibility of multiple cell upsets in the integrated circuits studied.

Topic: Radiation Effects in Electronics
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
CCDC 809775: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Assessment for cardiovascular fitness in patients with stroke: which cardiopulmonary exercise testing method is better?

Background Assessment for cardiovascular disease (CVD) is important in stroke patients, both being one of the main factors limiting success in stroke rehabilitation and its increased risk in stroke patients. Reduced exercise capacity after stroke decreases patients’ functionality and further increases the risk of CVD. Carefully selected cardiopulmonary exercise testing (CPET) can be safely used to determine the risk of CVD and to prescribe exercise program in stroke rehabilitation.Objectives The primary purpose of this study is to determine the most appropriate CPET in patients with stroke. The secondary aim is to determine the relationship between cardiorespiratory fitness and functional status of the patients.Methods Two CPETs using treadmill and bicycle ergometer protocols determined with a preliminary study were performed on participants. The main outcome measure was VO2peak. Patients were also evaluated according to Brunnstrom motor staging, Modified Ashworth Scale, Berg Balance Scale, and Functional Independence Measure.Results In total, 38 patients reached higher VO2peak values at treadmill test compared to bicycle test (p < 0.001). The mean VO2peak reached at treadmill CPET was 62% of the control group where mean VO2peak reached at bicycle was 76% of the control group. No significant correlation was found between Brunnstrom staging, spasticity, Berg Balance Scale, and VO2peak .Discussion The results of this study indicate that CPET can be performed safely in stroke patients when appropriate protocol was selected and that treadmill was more appropriate to determine cardiorespiratory fitness in this study population.

Topic: Cardiovascular and exercise physiology
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
A Conceptual Framework for the Teaching of U. S. Women's History

KATHRYN KISH SKLAR is Associate Professor of History at the University of California, Los Angeles. She is the author of numerous articles and the book Catharine Beecher: A Study in American Domesticity (1973), which was nominated for the National Book Award in Biography. In 1975-1976 she was a Fellow at the National Humanities Institute, New Haven, where she developed a sequence of courses in the social history of American women, 1600-1975. This essay has benefited from the generous criticism and comments of many colleagues and friends. Particularly important were the participants in two workshops at UCLA on Strategies and Problems in Teaching the Social History of American Women from 1600 to 1975. Fourteen specialists in U.S. women's history, who teach at colleges and universities in four southwestern states, contributed a great deal to my understanding of conceptual problems in U.S. women's history. They are: Professors Emily Abel, Marilyn G. Boxer, Patricia C. Cohen, Thomas Dublin, Barbara Epstein, Mary L. Felstiner, Estelle Freedman, Sherna Gluck, Helen Horowitz, Norma Fain Pratt, Ruth Rosen, Mary Rothschild, Mary P. Ryan, and Jane Slaughter. These workshops were funded by the National Endowment for the Humanities through a grant to the National American Studies Faculty. I am grateful to the NEH and ASA for their past support of this group. I am also grateful to the NEH-sponsored year I devoted to curriculum development in U.S. women's history at the National Humanities Institute, New Haven, 1975-76, where I began to develop some of the ideas on which this essay is based. Earlier versions of this paper were presented at the American Historical Association meeting last December and at Cornell in April. On both occasions it was improved by helpful comments from those in the audience-particularly from Irene Brown and Joan Jacobs Brumberg. This essay was also substantially assisted by extensive comments from Robert Byer, Dolores Hayden, Temma Kaplan, Alice Kessler-Harris, Gerda Lerner, and Mary Yeager. I am grateful to these colleagues, individually and collectively, for their help.

Topic: Historical Gender and Feminism Studies
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Audit Committee Attributes and Financial Reporting Quality: A Pre and Post Cama 2020 Empirical Analysis

The study investigated the impact of audit committee attributes on the financial reporting quality of listed manufacturing firms in Nigeria, comparing pre- and post-Companies and Allied Matters Act (CAMA) 2020 periods using data from 2017–2023 from the Nigerian Exchange group. Specifically the study evaluated the impact of audit committee independence, audit committee size and audit committee financial expertise which served as proxies of audit committee attributes on earnings variability which served as a proxy for financial reporting quality. Ex-post facto research design was used and the population covered all listed manufacturing firms; out of which, 25 firms were selected via purposive sampling technique. Findings revealed that larger audit committees were associated with improved reporting quality before CAMA 2020, but reduced committee size under the new regulation correlated with higher earnings variability indicating a decline in reporting quality. Audit committee independence consistently improved reporting quality, even with fewer directors post-CAMA 2020 and financial expertise showed a positive relationship with earnings variability. The study concluded that while larger committees and independent directors enhance reporting quality, the role of financial experts requires reevaluation to address governance shortcomings. The study therefore recommended that the provisions of CAMA 2020 be revisited to reconsider the reduction in audit committee size.

Topic: Auditing, Earnings Management, Governance
Subfield: Accounting
Field: Business, Management and Accounting
Domain: Social Sciences
Mathematics Literacy of Secondary Students in Solving Simultanenous Linear Equations

This study examines the profile of secondary students' mathematical literacy in solving simultanenous linear equations problems in terms of cognitive style of visualizer and verbalizer. This research is a descriptive research with qualitative approach. The subjects in this research consist of one student with cognitive style of visualizer and one student with cognitive style of verbalizer. The main instrument in this research is the researcher herself and supporting instruments are cognitive style tests, mathematics skills tests, problem-solving tests and interview guidelines. Research was begun by determining the cognitive style test and mathematics skill test. The subjects chosen were given problem-solving test about simultaneous linear equations and continued with interview. To ensure the validity of the data, the researcher conducted data triangulation; the steps of data reduction, data presentation, data interpretation, and conclusion drawing. The results show that there is a similarity of visualizer and verbalizer-cognitive style in identifying and understanding the mathematical structure in the process of formulating. There are differences in how to represent problems in the process of implementing, there are differences in designing strategies and in the process of interpreting, and there are differences in explaining the logical reasons.

Topic: Mathematics Education and Pedagogy
Subfield: Applied Mathematics
Field: Mathematics
Domain: Physical Sciences
Paper No P41: Predicting Change in Cell Gap in LCD Panels Subjected to Touch Force

Abstract Liquid crystal displays (LCDs) with touch‐screen capabilities are becoming increasingly popular. When a user pushes a screen too hard, the cell gap changes and causes a blur (known as touch mura) around the push location. This paper uses finite element analysis to predict the change in cell gap when an LCD panel is subjected to a touch force.

Topic: Material Properties and Processing
Subfield: Mechanics of Materials
Field: Engineering
Domain: Physical Sciences
[Preparations of alpha-lipoic acid: the dynamics of their content in the blood and their effect on hemostasis in lesions of the human liver].

The changes in blood coagulating activity before and after treatment with alpha-lipoic acid drugs as compared with blood lipoic acid content were studied in 130 patients with chronic diffuse diseases of the liver of the virus and alcohol etiology. A moderate correlation between the increase in blood alpha-lipoic acid concentration in patients with the liver diseases during the replacement therapy with alpha-lipoic acid drugs and a number of parameters of thrombelastogram was established. It was shown that relief of coenzyme deficit against the background of treatment with lipoic acid is associated with relief of hypocoagulative syndrome and an elevation of the blood ATP level. It is suggested that the ability of the coenzyme to stimulate the bioenergetic protection of hemostasis processes plays the important role in the mechanism of action of alpha-lipoic acid drugs.

Topic: Biochemical Acid Research Studies
Subfield: Biochemistry
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
A performance analysis of a typical server running on a cloud

In recent years, Cloud computing has become very popular from individuals to big enterprises because of the reduced cost, minimal management effort etc. Cloud providers like Amazon, Google are now offering resources for web deployment, storage, servers etc. However, due to the varying load and cost, evaluating the performance of task scheduling policies in these real Cloud environments is very challenging. In this paper, the performance of Earliest Deadline First (EDF) scheduling policy has been investigated using CloudSim and the hardware configuration of Amazon Web Services (AWS) and Google Cloud Platform (GCP) with the time-out of a web and FTP servers. In addition, a comparison between space-shared and time-shared task provisioning policies have been examined which shows that the average execution time can be minimised by using space-shared policy in both AWS and GCP.

Topic: Cloud Computing and Resource Management
Subfield: Information Systems
Field: Computer Science
Domain: Physical Sciences
Assessment of the Jason-2 Extension to the TOPEX/Poseidon, Jason-1 Sea-Surface Height Time Series for Global Mean Sea Level Monitoring

The Jason-2 (OSTM) follow-on mission to Jason-1 provides for the continuation of global and regional mean sea level estimates along the ground-track of the initial phase of the TOPEX/Poseidon mission. During the first several months, Jason-1 and Jason-2 flew in formation separated by only 55 seconds, enabling the isolation of inter-mission instrument biases through direct collinear differencing of near simultaneous observations. The Jason-2 Ku-band range bias with respect to Jason-1 is estimated to be −84 ± 9 mm, based on the orbit altitudes provided on the Geophysical Data Records. Modest improved agreement is achieved with the GSFC replacement orbits, which further enables the isolation of subtle (<1 cm) instrument-dependent range correction biases. Inter-mission bias estimates are confirmed with an independent assessment from comparisons to a 64-station tide-gauge network, also providing an estimate of the stability of the 17-year time series to be less than 0.1 mm/yr ± 0.4 mm/yr. The global mean sea level derived from the multi-mission altimeter sea-surface height record from January 1993 through September 2009 is 3.3 ± 0.4 mm/yr. Recent trends over the period from 2004 through 2008 are smaller and estimated to be 2.0 ± 0.4 mm/yr.

Topic: Geophysics and Gravity Measurements
Subfield: Oceanography
Field: Earth and Planetary Sciences
Domain: Physical Sciences
An exploratory study of aspirations for change and their effect on purpose among Catalan university students

Catalan young adults have found themselves as prominent actors in important social, political and economic changes that Catalonia is currently experiencing. How are their life goals related to these events? We explore self-oriented, prosocial and change-oriented life goals and their expected social benefits among 160 Catalan university students who completed an online survey. Mean differences between highly and scantly change-oriented students were strong in their endorsement of prosocial life goals and mild in self-oriented life goals. Linear regression found modest predictive value for students’ expectations of producing social benefits based on prosocial and change-oriented life goals, but not self-oriented life goals.

Topic: Youth Development and Social Support
Subfield: Safety Research
Field: Social Sciences
Domain: Social Sciences
Measurements and Assessment of Adiabatic Film Cooling Performance on a Gas Turbine Vane Endwall Using PSP Technique

Turbine vanes are typically assembled as a section containing single or double airfoil\nunits in an annular pattern. First stage guide vane assembly results in two common mating\ninterfaces - a gap between combustor and vane endwall while another from the adjacent\nsections, called slashface. High-pressure coolant could leak through these gaps to reduce\nthe ingestion of hot gas and achieve certain cooling benefit. As vane endwall region flow\nfield is already very complicated due to the presence of highly three-dimensional\nsecondary flows, then a significant influence on endwall cooling can be expected due to\nthe gap leakage flows. The entire study is divided into two parts. The first part of this\ndissertation investigates the endwall film cooling from gap leakage flows with the\nmultiple rows of discrete film cooling holes inside the passages. The later part studies the\nfilm cooling performance of multiple endwall cooling designs including inlet leakage jet.\nPressure Sensitive Paint (PSP) technique is used to obtain the detailed film cooling\neffectiveness distributions on the endwall of a scaled up mid-range industrial turbine vane\ngeometry. Experiments are performed in a blow-down wind tunnel cascade facility at the\nisentropic exit Mach number of 0.5 corresponding to Reynolds number of 3.8 x 105 based\non inlet conditions and axial chord length. Passive turbulence grid is used to generate\nfreestream turbulence level about 19% with an integral length scale of 1.7 cm. The effect\nof coolant-to-mainstream mass flow ratio and density ratio on the film cooling have been\nstudied. Results indicated that leakage coolants have significant influence on the endwall\nfilm cooling and different endwall cooling designs are capable of achieving higher cooling\neffectiveness with relatively uniform coverage

Topic: Turbomachinery Performance and Optimization
Subfield: Aerospace Engineering
Field: Engineering
Domain: Physical Sciences
Deciphering the protonation and tautomeric equilibria of firefly oxyluciferin by molecular engineering and multivariate curve resolution

The mysterious flashes of light communicated by fireflies conceal a rich and exciting solution spectrochemistry that revolves around the chemiexcitation and photodecay of the fluorophore, oxyluciferin. A triple chemical equilibrium by double deprotonation and keto-enol tautomerism turns this simple molecule into an intricate case where the relative spectral contributions of six chemical species combine over a physiologically relevant pH range, rendering physical isolation and spectral characterization of most of the species unmanageable. To disentangle the individual spectral contributors, here we demonstrate the advantage of chemical oriented multivariate data analysis. We designed a set of specific oxyluciferin derivatives and applied a multivariate curve resolution-alternating least squares (MCR-ALS) procedure simultaneously to an extensive set of pH-dependent spectroscopic data for oxyluciferin and the target derivatives. The analysis provided, for the first time, the spectra of the pure individual components free of contributions from the other forms, their pH-dependent profiles and distributions, and the most accurate to date values for the three equilibrium constants.

Topic: bioluminescence and chemiluminescence research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
chirps: API Client for CHIRPS

API Client for the Climate Hazards Group InfraRed Precipitation with Station Data 'CHIRPS'. The 'CHIRPS' data is a 35+ year quasi-global rainfall data set, which incorporates 0.05 arc-degrees resolution satellite imagery, and in-situ station data to create gridded rainfall time series for trend analysis and seasonal drought monitoring. For more details on 'CHIRPS' data please visit its official home page &lt;https://www.chc.ucsb.edu/data/chirps&gt;. Requests from large time series (&gt; 10 years) and large geographic coverage (global scale) may take several minutes.

Topic: Distributed and Parallel Computing Systems
Subfield: Computer Networks and Communications
Field: Computer Science
Domain: Physical Sciences