jimnoneill/paper-to-field-training huggingface dataset:
Dietary Energy Regulation During Gestation on Subsequent Lactational Response to Soybean Meal or Dried Brewers Grains

Forty-two Holstein cows were paired by body condition and mature equivalent milk production and fed either a high or low energy diet for the last 16 to 18 wk of lactation. Cows fed the high energy diet produced more milk (21.6 versus 17.6 kg/d), gained more body condition, and were heavier after calving (641 versus 591 kg) than cows fed the low energy diet. Beginning wk 3 postpartum, half the cows in each prepartum energy group were fed supplemental dried brewers grains or soybean meal. During wk 1 to 15 of lactation, cows from the high energy group produced more 3.5% fat-corrected milk (33.8 versus 31.3 kg/d), consumed less dry matter (23.2 versus 24.4 kg/d), and lost more body weight (-2.7 versus .9 kg/wk) compared with cows from the low energy group. Milk production, feed intake, and body weight change were not affected by protein source. The high amount of bound nitrogen in dried brewers grains resulting in decreased intestinal digestibility of escape protein may have been responsible for the lack of production response to this protein source.

Topic: Ruminant Nutrition and Digestive Physiology
Subfield: Agronomy and Crop Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Bonding of Aluminum Nitride to Copper for Reducing Thermal Stress

The crack susceptibility and properties of AlN to copper joints brazed with the Ag-27 mass%Cu-2%Ti filler metal and the Sn-38 mass%Pb solder were investigated. The heat conduction analysis suggested that the thermal conductivities of AlN-copper joints using the Ag–Cu–Ti insert metal added to tungsten interlayer and using the Sn–Pb solder with a thickness of less than 0.5 mm exceeded that of the AlN substrate (180 W/m·K). Thermal stress distribution in the AlN-copper joints was numerically calculated by a finite element method. The calculated maximum principal stress in AlN reduced by the use of a soft insert layer and/or a low expansivity interlayer. The crackings of brazed joints could be prevented when the tungsten interlayer thickness exceeded 0.8 mm in the brazed joint, and when the Sn–Pb solder was employed during the bonding operation. The tensile strength of the AlN-copper joints brazed at 1078 K for 120 s added to the 1.0 mm thick tungsten interlayer reached about 50 MPa, and that of the metallized AlN-copper soldered joints was about 20 MPa. The superior reliability for thermal cycling and heat conduction could be obtained for the AlN-W-copper joints using the Ag–Cu–Ti filler metal and titanium-copper multilayer-metallized AlN-copper joints using Sn–Pb solder.

Topic: Electronic Packaging and Soldering Technologies
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Data from EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape

&lt;div&gt;Abstract&lt;p&gt;Oncogenic signaling reprograms cancer cell metabolism to augment the production of glycolytic metabolites in favor of tumor growth. The ability of cancer cells to evade immunosurveillance and the role of metabolic regulators in T-cell functions suggest that oncogene-induced metabolic reprogramming may be linked to immune escape. EGF signaling, frequently dysregulated in triple-negative breast cancer (TNBC), is also associated with increased glycolysis. Here, we demonstrated in TNBC cells that EGF signaling activates the first step in glycolysis, but impedes the last step, leading to an accumulation of metabolic intermediates in this pathway. Furthermore, we showed that one of these intermediates, fructose 1,6 bisphosphate (F1,6BP), directly binds to and enhances the activity of the EGFR, thereby increasing lactate excretion, which leads to inhibition of local cytotoxic T-cell activity. Notably, combining the glycolysis inhibitor 2-deoxy-d-glucose with the EGFR inhibitor gefitinib effectively suppressed TNBC cell proliferation and tumor growth. Our results illustrate how jointly targeting the EGFR/F1,6BP signaling axis may offer an immediately applicable therapeutic strategy to treat TNBC. &lt;i&gt;Cancer Res; 76(5); 1284–96. ©2016 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;

Topic: Cancer, Hypoxia, and Metabolism
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
VAR MODEL UNTUK ANALISIS FOREIGN DIRECT INVESTMENT DI INDONESIA

Vector Autoregresive model is used to gives a more comprehensive view of how the relationship of FDI to economic growth, trade, exchange rate, the output value of the industry, and the interest rate in Indonesia. This study provides empirical evidence about the relationship which are interrelated to each other among the variables analyzed. By using VAR can analyze the impact of FDI on economic growth with other variables. The empirical results of whole analysis to give an answer to the original question posed in this study relate to how economic growth has been achieved, what the role of FDI and other spillovers in this process. Through the VAR model, the interdependence between the variables FDI, GDP, Trade, Industrial Output Value, Exchange Rate and Interest rates have been investigated in long-term relationships through cointegrating vectors and the short-term impact of the VAR model. Correlation of dynamic variables have been captured by the analysis of variance decomposition and impulse response.

Topic: International Business and FDI
Subfield: Strategy and Management
Field: Business, Management and Accounting
Domain: Social Sciences
The United States and the rise, fall and future prospects of the (Comprehensive and Progressive Agreement for) Trans-Pacific Partnership

The Trans-Pacific Partnership (TPP) is one of the most politically resilient economic&#13;\narrangements in the past decade. Its evolution including highs and lows is closely tied to the&#13;\nshifting positions of the United States (U.S.). This article examines the role played by the U.S.&#13;\nbehind the rise, fall and future of the TPP and its successor, the Comprehensive and Progressive&#13;\nAgreement for TPP (CPTPP). This article first revisits Washington’s three-fold geo-economic&#13;\ninterest behind the original TPP in terms of projecting influence in Asian affairs, supporting&#13;\nObama’s Rebalance to Asia strategy and leading the regional rule-writing efforts to facilitate&#13;\n21st century trade and investment. This article then delves into offering an explanation of the&#13;\nloss of the TPP in the U.S. It argues that the TPP was crippled under an overlay of bad timing,&#13;\nbad politics and bad context. Specifically, the 2016 elections, Trump’s disapproving views on&#13;\nthe TPP and the narrow, underperforming US trade policy ecosystem at large were the key&#13;\nfactors leading to the US withdrawal from the TPP. Lastly, the article ponders upon the future&#13;\nof the CPTPP by asking and answering three questions: Will China and other countries join the&#13;\nbloc? Will the CPTPP evolve into a Free Trade Area of the Asia-Pacific? Are the CPTPP and&#13;\nthe China-backed Regional Comprehensive Economic Partnership part of the Asia-Pacific’s&#13;\nconstructive response to Trump protectionism?

Topic: Global trade and economics
Subfield: General Economics, Econometrics and Finance
Field: Economics, Econometrics and Finance
Domain: Social Sciences
AP1.2 - A novel flexible room-temperature NO2 sensor based on WO3 integrated with white LED lamps

Miniaturized, portable and flexible WO 3 sensors illuminated by commercially available white LED lamps for ppb-level NO 2 detection at room temperature were successfully fabricated.The gold electrodes and LED lamps were integrated on the transparent substrates, in which the electrodes were deposited on the front side and the lamps were fixed at the back side.The hierarchical hollow WO 3 microspheres were solution-processed, and screen-printed on the substrate.The prepared sensor exhibits excellent response to ppb-level NO 2 in the range of 100-700 ppb, the sensitivity is as high as 13.3 even for 100 ppb NO 2 .The repeatability tests show that the sensor has a good repeatable performance.In addition, in contrast with the traditional room-temperature semiconductor gas sensors which are strongly influenced by humidity, the prepared sensor is less sensitive to humidity.

Topic: Gas Sensing Nanomaterials and Sensors
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Innovation Ecosystem Perspectives on Financial Services Innovation

The context of financial services has been characterised by changes in the&#13;\nregulatory, technological and societal landscape. Consumers are increasingly&#13;\ninterested in mobile payments, crowdfunding and microfinance services,&#13;\neither for themselves or because collaborative consumption is viewed as a&#13;\nmore sustainable. Retail branches are re-organised to further meet the&#13;\nexpectations of customers, start-ups focusing on technology for financial&#13;\nservices (i.e. Fintech) are ever growing and financial services companies&#13;\nreinforce their own innovation practices (e.g. creation of innovation labs or&#13;\nventure capital investment funds).&#13;\nThe innovation ecosystem around financial services companies represents the&#13;\nmany actors with whom they can co-create and co-produce innovative new&#13;\nservices for their customers (or for themselves). The innovation process is no&#13;\nlonger a closed internal effort but needs to include external actors from the&#13;\ninnovation ecosystem. This topic is especially interesting in a small and open&#13;\neconomy where the financial centre takes a prominent place in the economy.&#13;\nThe research question is therefore “How does the innovation ecosystem&#13;\ninfluence the innovation process within financial services companies?”.&#13;\nThe influence of the innovation ecosystem on the innovation process within&#13;\nfinancial service companies mainly comes from its social capital and value&#13;\ncreation efforts. However learning to work and exchange in an innovation&#13;\necosystem is also expected to influence the innovation process in place.&#13;\nRealizing the potential of the innovation ecosystem requires sufficient&#13;\ncapabilities to manage new information coming from the innovation&#13;\necosystem. The professional associations provide the necessary coordination&#13;\namong actors in the innovation ecosystem to co-create and appropriate value,&#13;\nwhile fostering co-evolution within the innovation ecosystem.

Topic: Digital Platforms and Economics
Subfield: Strategy and Management
Field: Business, Management and Accounting
Domain: Social Sciences
Theoretical and practical aspects of social sphere management in the Yamalo-Nenets Autonomous Okrug

This article discusses social management challenges in Arctic region, using the example of existing social issues in the cities of the Yamalo-Nenets Autonomous Okrug. The theoretical concept is based on the authors' ideas, who postulate rational management principles, the evolutionary transformation of modern society principles that imply the mutual influence of economic and social factors. In additional, this concept advocates the importance of humanization and harmonization of public relations, the significance of the human factor, and citizens' initiatives. Improving the social sphere in the northern region can be achieved through successful business practices and implementing market mechanisms that balance state, public, and private interests. The article argues that optimizing managerial regulation in the region's social sphere is based on well-established legislative practice of social welfare. An analysis of scientific literature, along with qualitative and quantitative empirical research, uncovered the most pressing social issues in the region. This analysis led to insights about the current state of the social sphere in the Yamalo-Nenets Autonomous Okrug and helped identify strategies to optimize management approaches that aim to enhance public trust in government authorities. The interpretation of primary sociological data allowed to highlight critical areas for socio-economic development in the region's cities, such as healthcare, education, housing affordability, rising utility prices, and access to consumer goods. The survey results revealed respondents' priorities, which included health, family, financial stability, employment, etc. Furthermore, the survey results underscored the necessity of considering public opinion on enhancing social infrastructure and establishing continuous feedback with residents regarding vital socio-economic development sectors in cities. In conclusion, the study emphasizes the importance of improving socially-oriented managerial efforts and adopting principle of integrity that considers both economic and social indicators. These indicators enhance overall satisfaction with the quality of public services, including medical, educational, and other services. Only a comprehensive strategy for addressing social challenges is crucial for fostering public well-being, improving human capital, and optimizing the social sphere in the region.

Topic: Arctic and Russian Policy Studies
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Low-viscosity and fast-curing polymer system for UV-based nanoimprint lithography and its processing

One of the key elements for the successful integration of nanoimprint lithography into industrial production processes is the availability of high-performance resist materials. In this contribution we present a novel low-viscosity and fast curing UV-NIL polymer, which is applied by spin-coating and designed for wafer-scale imprinting. Systematic investigations of photocurable components and photoinitiators led to the formulation of the polymer system mr-UVCur06. Film thicknesses in the range of 50 - 500 nm with excellent quality and uniformity could be obtained by spin-coating. Its suitability for UV-NIL processes was evaluated by means of imprinting tests and plasma etching investigations. This included investigations on imprinting with hard moulds, UV curing doses, resolution, etch rates using various plasma gases and pattern transfer. The beneficial flow behaviour of mr-UVCur06 led to short UV-NIL cycle times. Patterns of several orders of magnitude with feature sizes in the range of 30 nm to several tens of micrometers could be imprinted simultaneously. An example of a pattern transfer into Si was shown, where mr-UVCur06 was used as an polymer etch mask.

Topic: Nanofabrication and Lithography Techniques
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Religião e política no campo evangélico contemporâneo : ancoragens, homologias e retraduções

The presence of religious actors in the construction of public debate is, in Brazil, undisguised. Thus, we highlight the evangelical churches. Some denominations are relatively able to mobilize its members around specific demands or to broader political projects. However, religious filiations do not define political memberships. Affinity relationships between the two spheres are usually partial, and very complex. It is true that a faithful engaged in order to justify their political positions, will tend to evoke religious views available in the group to which it belongs. But this fact does not necessarily produce very stable identity convergences in the group, since the religious or political ideas are constantly retranslated by agents. Thus, the homologies raised here and regularities in the actions of individuals are contingent, however, always possible. Occasionally, they translate into modes of participation, inclusion of the faithful in public areas, political memberships and speeches somehow anchored to particular ways to experience religion. So it initially asks: what types of links between religion and politics are being produced in different social areas of interest to this investigation? Such homologies produce significant regularities, identity definitions? To tackle these problems, we used a focused research on participant observation that it intended to collate the political positions undertaken by evangelical believers focused on this work in the face of religious justifications for them mobilized. What entailed an analysis of the different discourses that try to justify the involvement of religious actors in the public debate. The thesis also searched far-reaching convergences in the contemporary evangelical discourse; also why, they were listed in the investigation two very different denominations: the Traditional and the second wave Pentecostals. Despite the diversity found within the studied groups, and the uniqueness of each religious denomination, the survey encountered a type of speech, widespread in varying degrees in religious spaces, it is called here pragmatic conservatism.

Topic: Religion and Society in Latin America
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Effects of Technology Support for Groups

In the context of a case study this paper explains some of the powerful impacts of technology support on teamwork which result in subtle changes in teams which appear over time. In consequence it is argued that the effects of computer support on teamwork are not easy to capture without looking at the object of study for a longer period of time and looking at the organisational context becomes relevant. In detail the study explores, whether computer support provides benefits to the launching of projects and, if so, what these benefits are. The basis of analyses is a case study of teamwork in a project which aims to introduce of standard software into a larger company. Therefore, this study tries to answer the following question: What is the contribution of computer support to the success of meetings in the early phases of a project (kick-off phase)?. Results show that in the short term an increase in efficiency is the main improvement arising from technology support. In the long run, technology enabled the project team to avoid negative effects of group dynamics since team members were enabled to reflect on their own development as a group.

Topic: Team Dynamics and Performance
Subfield: Social Psychology
Field: Psychology
Domain: Social Sciences
Hardware Efficient Approximative Matrix Inversion for Linear Pre-Coding in Massive MIMO

This paper describes a hardware efficient linear pre-coder for Massive MIMO Base Stations (BSs) comprising a very large number of antennas, say, in the order of 100s, serving multiple users simultaneously. To avoid hardware demanding direct matrix inversions required for the Zero-Forcing (ZF) pre-coder, we use low complexity Neumann series based approximations. Furthermore, we propose a method to speed-up the convergence of the Neumann series by using tri-diagonal pre-condition matrices, which lowers the complexity even further. As a proof of concept a flexible VLSI architecture is presented with an implementation supporting matrix inversion of sizes up-to 16 × 16. In 65 nm CMOS, a throughput of 0.5M matrix inversions per sec is achieved at clock frequency of 420 MHz with a 104K gate count.

Topic: Advanced Wireless Communication Techniques
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Pain management during pregnancy

Maternal adaptations in pregnancy are attributed to the hormones of pregnancy and to mechanical pressures arising from the enlarging uterus and other tissues. These adaptations protect the woman's normal physiological functions, meet the metabolic demands pregnancy imposes on the body, and provide for fetal development and growth needs (Bowback et al, 1995).

Topic: Pediatric Pain Management Techniques
Subfield: Pediatrics, Perinatology and Child Health
Field: Medicine
Domain: Health Sciences
A Digital Engineering Methodology for Design, Exploration and Validation of Safety‐Critical Software for Integrating AI‐based Algorithms

Abstract A strong shift towards the usage of AI/ML techniques is observed in a variety of applications and domains ranging from systems health monitoring, and fuel optimization up to novelties like Collision Avoidance and Unmanned Air Mobility. Developing such systems is challenging given the required levels of safety, autonomy, and the complexity of the environmental conditions. To provide guidance, standardization bodies like SAE, EUROCAE, and ISO work on guidelines for AI/MLs integration into safety‐critical systems (e.g., ED‐324/ARP6983 in aeronautics, ISO/PAS‐8800 in automotive). In this work, some AI/ML challenges are first surveyed including limited embedded HW resources and the AI/ML uncertainty. Then, a modular, iterative Digital Engineering Methodology based upon SysML® v2 is introduced to support AI/ML design and development. The methodology is aligned with the Department of Defense Digital Engineering Directive 5000.97 and the MIL‐STD‐881f standard for structuring work breakdown. To ensure datasets quality, the methodology includes validation of properties of the Operational Design Domain (ODD) like completeness, representativeness, and independence. To characterize the ML model, techniques are applied to assess stability, generalization, and robustness. Last, to validate system safety a probabilistic scenario‐based method is introduced to ensure the ML performance remains within safety thresholds. The approach is illustrated by a formation flying Use Case integrating a Reinforcement Learning model, and some MBSE techniques for engineering requirements, system, architecture, and ODD. Some perspectives towards the consolidation of the proposed methodology and to foster AI/ML maturity are finally given.

Topic: Software Reliability and Analysis Research
Subfield: Software
Field: Computer Science
Domain: Physical Sciences