jimnoneill/paper-to-field-training huggingface dataset:
Cumulative generation of electricity from the wind of passing vehicles and natural wind in the Bukhara region of the Republic of Uzbekistan

Wind energy occupies are a rather important place in the balance of global “green” generation. Wind energy directly depends on the wind speed in the region under consideration. The highest average wind speed during the year is observed in the Bukhara region of the Republic of Uzbekistan. Vertical wind generators are widely used to collect the energy of natural wind and air movement generated by traffic into electricity. In order to effectively use the power of natural wind and air turbulence that occurs during the movement of vehicles, it is proposed to install vertical wind generators on the side of highways of international importance in the Bukhara region at certain intervals of the road.

Topic: Engineering and Agricultural Innovations
Subfield: Aquatic Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
CO<sub>2</sub> Laser Scattering from Turbulence in Tokamaks

We report a study of electron density fluctuations in the Adiabatic Toroidal Compressor (ATC) Tokamak using heterodyne detection to study the small angle scattering of CO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> laser radiation. The scattering apparatus described below allows us to study fluctuations with wavelengths from 1 to 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−3</sup> cm, frequencies from 10kHz to 1GHz and fluctuation amplitudes ñn as low as 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−5</sup> (where ñ is the total fluctuation amplitude and n is the electron density)[1]. We observed scattering due to density fluctuations at frequencies ω/2Π below 2MHz and wavelengths λ from 0.3 to 1cm These fluctuations are predicted to be driven in contained plasmas by density and temperature gradients. The observed turbulence may play an important role in electron transport phenomena in prototype fusion reactors similar to the ATC.

Topic: Magnetic confinement fusion research
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
Aberrant histone modification in CD19+ B cells of the patients with chronic lymphocytic leukemia

Keshu Zhou, Qing Zhang, Yanyan Liu, Yuanyuan Xiong, Shengsheng Wu, Jingke Yang, Hu Zhou, Xinjian Liu, Xudong Wei, Yongping Song Department of Hematology, Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou, People&amp;amp;rsquo;s Republic of China Abstract: The aim of this study was to detect the alterations in histone methylation and acetylation in patients with chronic lymphocytic leukemia (CLL). Global histone H3/H4 acetylation and H3K4/H3K9 methylation were detected by the EpiQuik&amp;amp;trade; global histone H3/H4 acetylation and H3K4/H3K9 methylation assay kits. The mRNA expression of selected chromatin modifier genes was measured by real-time polymerase chain reaction (RT-PCR). Our results found that the global histone H3/H4 hypoacetylation in the CD19+ B cells of patients with CLL (P=0.028 and P=0.03, respectively) and the global histone H3K9 methylation in patients with CLL were significantly increased compared with controls (P=0.02), while there was no significant difference in the global histone H3K4 methylation between the two groups. The level of SIRT1 and EZH2 mRNA expression was upregulated in patients with CLL (P=0.03 and P=0.02, respectively), which increased significantly with progression from Binet stage A to stage C (P=0.015 and P=0.01, respectively) and Rai good to high risk stage (P=0.007 and P=0.008, respectively). The level of HDAC1 and HDAC7 mRNA expression was significantly increased (P=0.02 and P=0.008, respectively) and HDAC2 and P300 mRNA expression was reduced in patients with CLL (P=0.002 and P=0.001, respectively). In conclusion, it is observed that the aberrant histone modification plays an important role in the pathogenesis of CLL. Keywords: histone methylation, histone acetylation, SIRT1, EZH2, CLL

Topic: Chronic Lymphocytic Leukemia Research
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Supervised<i>t</i>-Distributed Stochastic Neighbor Embedding for Data Visualization and Classification

We propose a novel supervised dimension-reduction method called supervised t-distributed stochastic neighbor embedding (St-SNE) that achieves dimension reduction by preserving the similarities of data points in both feature and outcome spaces. The proposed method can be used for both prediction and visualization tasks with the ability to handle high-dimensional data. We show through a variety of data sets that when compared with a comprehensive list of existing methods, St-SNE has superior prediction performance in the ultrahigh-dimensional setting in which the number of features p exceeds the sample size n and has competitive performance in the p ≤ n setting. We also show that St-SNE is a competitive visualization tool that is capable of capturing within-cluster variations. In addition, we propose a penalized Kullback–Leibler divergence criterion to automatically select the reduced-dimension size k for St-SNE. Summary of Contribution: With the fast development of data collection and data processing technologies, high-dimensional data have now become ubiquitous. Examples of such data include those collected from environmental sensors, personal mobile devices, and wearable electronics. High-dimensionality poses great challenges for data analytics routines, both methodologically and computationally. Many machine learning algorithms may fail to work for ultrahigh-dimensional data, where the number of the features p is (much) larger than the sample size n. We propose a novel method for dimension reduction that can (i) aid the understanding of high-dimensional data through visualization and (ii) create a small set of good predictors, which is especially useful for prediction using ultrahigh-dimensional data.

Topic: Face and Expression Recognition
Subfield: Computer Vision and Pattern Recognition
Field: Computer Science
Domain: Physical Sciences
Regarding of legislation on Cellular Therapy. A case report

This manuscript is centered on novel aspects of the legislation on “Cell Therapy” through the case of a patient who underwent intrarticular treatment with an uncharacterized cellular product from which complications arose. It aims to alert the medical community that could act outside the regulations concerning advanced therapies, implying a risk of iatrogenic actions and consequent litigation processes. The commercial expansion of devices that offer cellular products without the control of the Health Administration makes it advisable to pay extreme attention to these legislative aspects.

Topic: Biomedical Ethics and Regulation
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Chromosome abnormalities in patients with syndactyly.

Chromosome studies on 105 patients with syndactyly included two trisomy-21 mongols, a chromatin-positive boy with 47, XXY, a chromatin-negative short girl with 45,X0 and a boy with a familial D/D translocation. Chromosome patterns were normal in the other cases which included three patients with acrocephalosyndactyly and one patient with oro-facial-digital syndrome.The incidence of chromosome abnormalies was greater than expected since syndactyly of the fingers is uncommon in the chromosome disorders.THIS INCIDENCE MAY BE RELATED TO THE INCREASED MATERNAL AGE (MEAN: 29.4 years) of the syndactyly group compared to maternal age (mean: 26.64 years) of the control group although, paradoxically, four mothers of the five patients with chromosome abnormalities were young.

Topic: Congenital limb and hand anomalies
Subfield: Developmental Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Do Health Benefits Outweigh the Costs of Mass Recreational Programs? An Economic Analysis

ABSTRACT One promising public health intervention for promoting physical activity is the Ciclovía program. The Ciclovía is a regular multisectorial community-based program in which streets are temporarily closed for motorized transport, allowing exclusive access to individuals for recreational activities and physical activity. The objective of this study was to conduct an analysis of the cost–benefit ratios of physical activity of the Ciclovía programs of Bogotá and Medellín in Colombia, Guadalajara in México, and San Francisco in the USA. The data of the four programs were obtained from program directors and local surveys. The annual cost per capita of the programs was: US $6.0 for Bogotá, US $23.4 for Medellín, US $6.5 for Guadalajara, and US $70.5 for San Francisco. The cost–benefit ratio for health benefit from physical activity was 3.23–4.26 for Bogotá, 1.83 for Medellín, 1.02–1.23 for Guadalajara, and 2.32 for San Francisco. For the program of Bogotá, the cost–benefit ratio was more sensitive to the prevalence of physically active bicyclists; for Guadalajara, the cost–benefit ratio was

Topic: Urban Transport and Accessibility
Subfield: Transportation
Field: Social Sciences
Domain: Social Sciences
Profil Kondiloma Akuminata di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado Periode Januari 2013 sampai Desember 2013

Abstract: Condyloma acuminata (CA) is a certain type of human papilloma virus (HPV) vegetation, stemmed from a jagged surface. This study was aimed to obtain the profil of CA cases at the Department of Dermatovenerology Prof. Dr. R. D. Kandou Hospital Manado. This was a retrospective study using the medical record data of Polyclinic Dermatovenerology. The results showed that there were 40 patients (3.7%) with CA out of 1077 patients with skin diseases. Most of the patients were females (25 patients; 62.5%), in the age group of 25-44 years (19 patients; 47%), and worked as private workers (15 patients; 37 %). The most common location of the lesions in females was vulva (8 patients; 32%), and in males was glans penis (6 patients (40%). 28 patients (70%). The most comorbidity was candidiosis vulva vaginalis (CVV) as many as 5 patients (12.5%). Conclusion: In this study, most patients were females, age group of 25-44 years, and private worker. The most common location of CA was vulva in females and glans penis in males. Most patients were treated with podophylline. The most common comorbidity was CVV.Keywords: condyloma acuminata, human papilloma virus Abstrak: Kondiloma akuminata (KA) adalah vegetasi Human Papiloma Virus (HPV) tipe tertentu, bertangkai, dengan permukaan berjonjot. Penelitian ini bertujuan untuk mendapatkan profil penyakit kondiloma akuminata di Poliklinik Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado periode Januari 2013 sampai Desember 2013. Jenis penelitian ialah deskriptif retrospektif menggunakan data rekam medik dan buku register infeksi menular seksual di Poliklinik Ilmu Penyakit Kulit dan Kelamin RSUP Prof. Dr. R. D. Kandou Manado. Hasil penelitian mendapatkan jumlah penderita KA sebanyak 40 orang (3,7%) dari 1077 pasien penderita penyakit kulit yang datang berobat. Jumlah penderita KA terbanyak pada kelompok usia 25-44 tahun yaitu 19 orang (47%), jenis kelamin perempuan dengan jumlah 25 orang (62,5%), pekerja swasta yaitu 15 orang (37%), Lokasi lesi terbanyak pada perempuan terdapat di vulva sebanyak 8 orang (32%) sedangkan lokasi lesi terbanyak pada laki laki terdapat di glans penis sebanyak 6 orang (40%), Terapi yang paling sering diberikan ialah podofilin yaitu sebanyak 28 orang (70%), Penyakit penyerta terbanyak ialah kandidiosis vulva vaginalis (KVV) sebanyak 5 orang (12,5%). Simpulan: Dalam penelitian ini, pasien KA terbanyak pada kelompok usia 25-44 tahun, berjenis kelamin perempuan, pekerjaan swasta, lokasi lesi pada perempuan tersering di vulva sedangkan pada laki-laki tersering di glans penis, dan pengobatan dengan podofilin. Penyakit penyerta terbanyak ialah KVV.Kata kunci: kondiloma akuminata, human papilloma virus

Topic: Cervical Cancer and HPV Research
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Water space in the Turgenev's novel «The day before»: philosophical and mifipoetichesky

The nature images of the Turgenev's novel «The Day Before» are examined in the article and connected with the area of water space. Nature is always a focus of philosophical writer's thought and depth of memory, which is reflected in its mythopoetic semantics. The article is devoted to the correlation of consciousness and unconsciousness in that Turgenev's novel.

Topic: Russian Literature and Bakhtin Studies
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
The research on the connotation characteristics and policy analysis of smart urban agglomeration under holistic governance

After nearly a decade of practice and exploration, the construction of smart cities in China still exposes many practical difficulties that are hard to break through. Driven by the longterm prospect of smart society, the construction of smart urban agglomeration provides a new idea for breaking the bottleneck of construction and promoting the phased achievement of smart society. Based on the internal logic of holistic governance theory, this study makes a theoretical interpretation of the connotation and characteristics of smart urban agglomerations, and puts forward that smart urban agglomerations have four characteristics: combination of goals and concepts, integration of regional governance, complementary application of technologies and coordination of industrial functions. At the same time, combining with the policy planning of China's major urban agglomerations, this study analyzes the key policy points of China's smart urban agglomerations development from three aspects of technology foundation, resource integration and application system. Therefore, we conclude that as a transitional development model between smart city and smart society, smart urban agglomeration is not only a further extension of the new smart city in the spatial scope, but also a forward-looking thinking to integrate the fragmented and distributed smart city.

Topic: Smart Cities and Technologies
Subfield: Media Technology
Field: Engineering
Domain: Physical Sciences
CCDC 921289: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Effect of Temperature on the Extraction of β-Glucan from Different Jeju Barley Varieties

The effect of different temperatures (45, 55, 65, and <TEX>$75^{\circ}C$</TEX>) on the extraction of <TEX>${\beta}$</TEX>-glucan and the properties of extracted <TEX>${\beta}$</TEX>-glucan were investigated with four different varieties of barley. Jeju naked barley, blue barley, beer barley, and black barley contained 6.85, 5.13, 3.58, and 4.16% of <TEX>${\beta}$</TEX>-glucan, respectively. <TEX>${\beta}$</TEX>-glucan in barley was extracted in the range of 64.88 to 93.84% depending on the extraction temperature and barley variety. The <TEX>${\beta}$</TEX>-glucans in Jeju naked barley, Jeju blue barley, and black barley were optimally extracted at <TEX>$65^{\circ}C$</TEX> for 3 h and Jeju beer barley at <TEX>$75^{\circ}C$</TEX>. The extracted <TEX>${\beta}$</TEX>-glucan resolubilized to 43.48-81.73% and the ratio of <TEX>${\beta}(1{\rightarrow}3)$</TEX> to <TEX>${\beta}(1{\rightarrow}4)$</TEX> linkage was in the range of 1:3.8-5.8. These results suggest that purification and properties of <TEX>${\beta}$</TEX>-glucan depend not only on the water extraction temperature, but also on the barley variety.

Topic: Food composition and properties
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Von HÜgel and Catholic Education

Trois themes cle coexistent dans la theorie catholique contemporaine de l'education, le developpement integral de la personne, l'autonomie des disciplines et la synthese de la foi, de la vie et de la culture; ceci dans une tension qui n'est pas toujours creative. Le but du present article est de demontrer, au moyen des points de vue et de l'exemple du baron Friedrich von Hugel (1852-1925), que la tentative catholique de combiner ce qui distingue et ce qui englobe est a la fois possible et fructueuse, et que les themes cle du developpement humain integral, des disciplines autonomes et d'une synthese foi/vie/culture peuvent etre interpretes et compris de telle sorte qu'ils se soutiennent et s'eclairent mutuellement.

Topic: Religious Education and Schools
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Trends of Coronary Artery Bypass Grafting Performance in a Cohort of Hospitals in China Between 2013 and 2018

Background: China has witnessed a rapid increase in the volume of coronary artery bypass grafting (CABG) but substantial gaps in the performance for CABG across the nation. The present study aimed to investigate the change in CABG performance after years of quality improvement measures in a national registry in China. Methods: The study included 66 971 patients who underwent isolated CABG in a cohort of 74 tertiary hospitals in China between January 2013 and December 2018. Data were collected from the Chinese Cardiac Surgery Registry. Outcomes were in-hospital mortality and postoperative length of stay. Five process measures for surgical technique and secondary prevention were also analyzed. We described the changes in the overall performance and interhospital heterogeneity across the years. Results: The in-hospital mortality declined from 0.9% in 2013 to 0.6 in 2018, with a risk-adjusted odds ratio of 0.66 (95% CI, 0.46–0.93; P &lt;0.001). The standard mean difference for risk-standardized mortality rate between hospitals in the lowest and highest quartile narrowed from 1.63 in 2013 to 1.35 in 2018. The median (interquartile range) hospital-level rate of using arterial graft increased from 93.9% (86.0%–97.8%) to 94.6% (83.3%–99.2%), but the difference was not statistically significant. Meanwhile, the rate of free from blood transfusion increased from 17.0% (2.6%–32.0%) to 34.1% (8.8%–52.9%). The hospital-level rate of prescribing β-blockers at discharge significantly increased from 82.8% (66.7%–90.3%) to 91.1% (82.1%–97.1%), statin from 75.8% (55.7%–88.9%) to 88.9% (75.0%–96.0%), and aspirin from 90.3% (83.9%–95.2%) to 95.3% (88.9%–98.1%). Conclusions: In the Chinese Cardiac Surgery Registry, there were notable improvements in the treatment process related to CABG and decline of in-hospital mortality with reduced interhospital heterogeneity.

Topic: Acute Myocardial Infarction Research
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Investigation of the early response to rat forepaw stimulation

The role of relative cerebral blood volume (rCBV) in the early response of blood oxygenation level-dependent (BOLD) signal following sensory stimulation was assessed. Magnetic resonance imaging (MRI) measurements of rCBV and BOLD signal as a function of time (t) were compared with relative cerebral blood flow (rCBF) obtained by laser doppler flowmetry during a repeated epoch of rat forepaw stimulation in which 6 sec of electrical stimulation followed 54 sec of rest. rCBF(t) exceeded rCBV(t) in somatosensory cortex at all time points and reached a maximal increase (60%) during a 6 sec stimulation that was much higher than maximal rCBV (10%). An initial dip was not observed in BOLD signal, which showed a delay with respect to rCBF that was roughly consistent with the cerebral blood transit time. Magn Reson Med 41:247–252, 1999. © 1999 Wiley-Liss, Inc.

Topic: Advanced MRI Techniques and Applications
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Effect of Corporate Tax Avoidance on the Investment-cash Flow Sensitivity

Abstract This paper aims to disclose the comprehensive effect of corporate tax avoidance on investment cash flow sensitivity. for this purpose, a number of enterprises listed on shanghai and shenzen stock exchanges (a-share enterprises) during 2009∼2015 were selected to explore the effect of corporate tax avoidance on the free cash flow of enterprises. in light of the preivous studies, an investment cash flow sensitivity model was created based on book-tax difference (btd), and the descriptive statistics were subjected to regression analysis. the research reveals that enterprises with a high level of tax avoidance have a high investment cash flow sensitivity; tax avoidance of an enterprise can directly increase the cash flow, and suppress the cash flow by raising the deferred financing cost. the research findings shed new light on the decision-making of corporate tax avoidance.

Topic: Corporate Taxation and Avoidance
Subfield: Accounting
Field: Business, Management and Accounting
Domain: Social Sciences
Devenir intracellulaire des vecteurs AAV dans les cellules dendritiques humaines et conséquences sur le transfert de gène

Les vecteurs viraux dérivés du virus adéno-associé (AAV) apparaissent depuis deux décennies, comme des outils efficaces pour le transfert de gène in vivo. Cependant, malgré une faible immunogénicité et une absence de toxicité in vivo, leur optimisation requiert encore un effort important vers une meilleure compréhension de leur biologie et, en particulier, de leur interaction avec le système immunitaire. Au cours de ce travail de thèse, nous avons utilisé une méthode de sélection dirigée in vitro dans le but d’obtenir un variant de capside capable de transduire efficacement un type cellulaire non-permissif aux vecteurs AAV : les cellules dendritiques (DC). En effet, ces cellules jouent un rôle primordial dans l’établissement de la réponse immunitaire et, par conséquent, dans la persistance de l’expression du transgène in vivo. Cette technologie, très répandue dans la communauté AAV, a permis de sélectionner un variant de capside aux propriétés très intéressantes. La mutation sélectionnée, caractérisée in vitro comme induisant une instabilité de la capside, a permis d’identifier et de surmonter un point de blocage majeur dans le processus de transduction des DC par les vecteurs AAV consistant dans l’étape de décapsidation du génome du vecteur dans le noyau cellulaire. De manière intéressante, le variant obtenu exhibe un avantage en terme de transduction non seulement dans les DC mais aussi dans différents modèles de cellules primaires humaines (e.g. HUVEC) ou animales (OBC), peu ou pas permissive à l’AAV. De plus, des expériences de transfert de gène in vivo réalisées dans un modèle murin, indiquent que le variant sélectionné conduit à une meilleure expression du transgène, possiblement due à la mise en place d’un processus de tolérisation. Les propriétés remarquables de ce variant de capside, font de lui un candidat intéressant pour des applications médicales.

Topic: Virus-based gene therapy research
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences