jimnoneill/paper-to-field-training huggingface dataset:
Finding a suitable hop-to-hop busty traffic transmission approach for underwater acoustic networks: handshake-based vs. handshake-free MAC protocols

Any medium access control (MAC) protocol designed for underwater acoustic networks (UANs) must take some unique characteristics of underwater channels into consideration for apt functioning, such as long propagation delay, high bit-error rate, limited bandwidth and so forth. Already, many MAC protocols are designed for UANs, which have fully or partially taken these characteristics into account and could be classified as handshake-free and handshake-based protocols. In this paper, these two classes are investigated through a comprehensive simulation campaign by employing their prominent representative protocols, namely ALOHA, carrier sense multiple access (CSMA) and multiple access with collision avoidance based adaptive packet train (MACA-APT) protocol. The contribution of this paper lies as follows: (i) unearthing the optimum values of various parameters on which the performance of a protocol relies; (ii) investigating the performance of all three protocols through a realistic channel model simulator by varying a couple of network parameters, and iii) discovering their effectiveness on various applications.

Topic: Underwater Vehicles and Communication Systems
Subfield: Ocean Engineering
Field: Engineering
Domain: Physical Sciences
The Future of Science Training: Institutional and Departmental Recommendations from Trainees

For over twenty years, reports from the National Academies of Science, Engineering, and Medicine and other groups have recommended changes to improve the training environments of graduate and postdoctoral trainees and promote a sustainable STEM workforce. In a hypercompetitive climate with a shortage of funds, academic institutions and departments have largely failed to prioritize and implement these recommendations, leading to a lack of change and exacerbation of problems. Here, we describe seven concrete and implementable changes, developed as part of a set of larger guidelines at a national meeting of stakeholders from across career stages, that departments and programs can make to improve their training environments.

Topic: Health and Medical Research Impacts
Subfield: Public Health, Environmental and Occupational Health
Field: Medicine
Domain: Health Sciences
Active Vibration Control of Seismically Excited Building Structures by Upgraded Grey Wolf Optimizer

In recent decades, active vibration control of buildings for earthquake-induced damage mitigation has been widely considered in the scientific literature. Fuzzy logic control (FLC) has been shown to be an effective approach to regulate control forces exerted by actuators to building structures to reduce earthquake-borne oscillations. In many cases, FLC definition relying solely on expert knowledge does not result in optimal control responses for structures under strong ground motions. Thus, FLC optimal design becomes critical. In this regard, this paper puts forth an enhanced version of the metaheuristic Grey Wolf Optimizer (UGWO) to optimally design membership functions and rule base of FLC to minimize seismic structural damage defined in terms of maximum curvature ductility ratio at the end of structural members. The potential of UGWO for the purpose is demonstrated by considering a FLC implemented to control the seismic response of a 20-story steel structure with nonlinear behavior through active actuators. The performance of the UGWO is gauged by examining nine different structural performance metrics and compared to results from 5 different widely used state-of-art metaheuristic optimization algorithms including the original Grey Wolf Optimizer. Comparisons demonstrate the capability of UGWO in providing better solutions in most of cases, resulting in reduced structural response and damage of the considered building.

Topic: Vibration Control and Rheological Fluids
Subfield: Civil and Structural Engineering
Field: Engineering
Domain: Physical Sciences
Non-pancreatitis-Related Abdominal Pain Following ERCP in Patients With Pancreas Divisum

Introduction: Non-pancreatitis Post ERCP abdominal pain (NPPEP) is not uncommon following ERCP with minor papilla therapy. ERCP for pancreas divisum is technically demanding procedure requiring direct pancreatic duct manipulation. Non-Pancreatitis related pain following ERCP in patients with divisum has not been well evaluated. Methods: A retrospective case-control study in patients with divisum undergoing ERCP was conducted. NPPEP was defined as post ERCP abdominal pain without clinical, biochemical and radiological evidence of post ERCP pancreatitis (PEP). Patients with a diagnosis of PEP were excluded. Patients with NPPEP were compared with procedural complexity-matched controls without post ERCP abdominal pain in 1:2 ratio for demographic and procedure related factors. Descriptive analysis as well as paired t test and chi-square test were performed for analysis. Results: A total of 174 ERCPs performed in patients with divisum were reviewed. Out of all procedures, the incidence of NPPEP was 14%. (24/174) which was significantly higher than observed incidence of PEP of 5% (9/174) (P - 0.006). In patients with NPPEP, the average age was 34.6 years, 60% were male, 70% were Caucasian. 77% had complete divisum. 37% procedures were performed on native papilla. 80% procedures were ASGE complexity grade 3. The patients with NPPEP were admitted for an average of 3.3 days. 40% received rectal Indomethacin during the procedure. The average procedure time was 71.5 mins. 40% of patients were active smokers and 40% drank alcohol. 50% of patients were on home opioids. Compared to an ASGE complexity-matched control group, patients in the NPPEP group were younger (35 vs. 55 years, P=0.02). ROC curves showed age <49 years had sensitivity and specificity of of 64% and 63% respectively. There were no other differences in demographics and procedure related interventions between the two groups. Conclusion: The incidence of NPPEP was 17%, significantly higher than the observed incidence of PEP in this cohort. NPPEP was more common in younger patients (<49 years). Neither Indomethacin nor minor papilla stent placement impacted the risk of NPPEP. Attention to the rate of NPPEP following minor papilla intervention may help allay unnecessary testing in patients undergoing ERCP with minor papilla therapy. In the study institution, many patients have a scheduled admission following the index ERCP for pancreas divisum for close observation and pain management.Table: Table. Comparison between patients with non-pancreatitis post-ERCP pain (NPPEP) with patients without any post-procedure complications

Topic: Gallbladder and Bile Duct Disorders
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Asi1 is an inner nuclear membrane protein that restricts promoter access of two latent transcription factors

Stp1 and Stp2 are homologous transcription factors in yeast that are synthesized as latent cytoplasmic precursors with NH2-terminal regulatory domains. In response to extracellular amino acids, the plasma membrane–localized Ssy1–Ptr3–Ssy5 (SPS) sensor endoproteolytically processes Stp1 and Stp2, an event that releases the regulatory domains. The processed forms of Stp1 and Stp2 efficiently target to the nucleus and bind promoters of amino acid permease genes. In this study, we report that Asi1 is an integral component of the inner nuclear membrane that maintains the latent characteristics of unprocessed Stp1 and Stp2. In cells lacking Asi1, full-length forms of Stp1 and Stp2 constitutively induce SPS sensor–regulated genes. The regulatory domains of Stp1 and Stp2 contain a conserved motif that confers Asi1-mediated control when fused to an unrelated DNA-binding protein. Our results indicate that latent precursor forms of Stp1 and Stp2 inefficiently enter the nucleus; however, once there, Asi1 restricts them from binding SPS sensor–regulated promoters. These findings reveal an unanticipated role of inner nuclear membrane proteins in controlling gene expression.

Topic: Genomics and Chromatin Dynamics
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Expanded Emergency Management Roles and Missions for the National Guard.

Abstract : When called to do so, the military assists in meeting the country's domestic emergency needs. The National Guard (NG) is the initial component to be assigned these missions. However, Active Component (AC) troops are frequently employed even when the NG among the states in the region have the capacity to meet overall mission requirements. This unnecessary commitment of AC resources occurs because of inadequate planning or lack of coordination of Guard capabilities or inflexible government regulation which precludes employment of the NG. The nation continues to increase AC employment while we are reducing defense budgets and military personnel. This paper reviews the current policy, organization, and processes for military responses to domestic emergencies. Recommendations are made to improve cost effectiveness and response time, and to reduce the AC's optempo. The proposals are based substantially on the NG's increasing capacity for involvement in domestic support operations.

Topic: Military and Defense Studies
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
An aluminum hydroxide:CpG adjuvant enhances protection elicited by a SARS-CoV-2 receptor binding domain vaccine in aged mice.

Global deployment of vaccines that can provide protection across several age groups is still urgently needed to end the COVID-19 pandemic, especially in low- and middle-income countries. Although vaccines against SARS-CoV-2 based on mRNA and adenoviral vector technologies have been rapidly developed, additional practical and scalable SARS-CoV-2 vaccines are required to meet global demand. Protein subunit vaccines formulated with appropriate adjuvants represent an approach to address this urgent need. The receptor binding domain (RBD) is a key target of SARS-CoV-2 neutralizing antibodies but is poorly immunogenic. We therefore compared pattern recognition receptor (PRR) agonists alone or formulated with aluminum hydroxide (AH) and benchmarked them against AS01B and AS03-like emulsion-based adjuvants for their potential to enhance RBD immunogenicity in young and aged mice. We found that an AH and CpG adjuvant formulation (AH:CpG) produced an 80-fold increase in anti-RBD neutralizing antibody titers in both age groups relative to AH alone and protected aged mice from the SARS-CoV-2 challenge. The AH:CpG-adjuvanted RBD vaccine elicited neutralizing antibodies against both wild-type SARS-CoV-2 and the B.1.351 (beta) variant at serum concentrations comparable to those induced by the licensed Pfizer-BioNTech BNT162b2 mRNA vaccine. AH:CpG induced similar cytokine and chemokine gene enrichment patterns in the draining lymph nodes of both young adult and aged mice and enhanced cytokine and chemokine production in human mononuclear cells of younger and older adults. These data support further development of AH:CpG-adjuvanted RBD as an affordable vaccine that may be effective across multiple age groups.

Topic: SARS-CoV-2 and COVID-19 Research
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Response status as predictor of survival after autologous hematopoietic cell transplant (AHCT), without or with consolidation (with bortezomib, lenalidomide (Len) and dexamethasone) and len maintenance (AM vs. ACM) versus tandem AHCT and len maintenance (TAM) for up-front treatment of patients (pts) with multiple myeloma (MM): BMT CTN0702-stamina (NCT01109004).

8010 Background: The Stamina trial primarily aimed to identify the best strategy among AM, ACM, and TAM, leading to longer PFS (LBA-1, ASH, 2016). Here we report on interim, exploratory results of the association between PFS and overall survival (OS) and baseline MM response, risk category, and treatments (Rx). Methods: Pts with MM, &lt; 71 years, &lt; 12 mos from diagnosis were randomized to melphalan 200mg/m 2 (mel) and AHCT (AM), tandem mel AHCT (TAM), or mel AHCT and 4 cycles of RVD ((ACM). Pts received Len till progression. Pts were stratified by high risk vs. standard ( del13q, del17q, t(4;14), t(14;16), t(14;20) and hypodyploid; high β2 microglobulin). Kaplan Meier estimates of PFS and OS were performed as a function of Rx and ≥ very good partial response (VPGR including CRs) vs. &lt; VGPR. Cox proportional hazard models explored associations between PFS or OS and risk category, Rx, and ≥ VPGR vs. &lt; VGPR. Results: Between 6/2010-11/2013, 758 pts (AM, N = 257; ACM, N = 254; TAM, N = 247) aged 20-70 years (median 57y) were enrolled (24% high-risk). Baseline ≥VGPR responses were 45.5- 49.8%. PFS at 38 months was similar. For &lt; VGPR, 38-mos PFS with TAM:55.8% (95%CI: 45.8%, 64.7%); ACM: 54.0% (44.7%, 62.5%); AM: 50.1% (40.6%, 58.9%); For ≥VGPR, 38-mos PFS with TAM: 57.1% (46.8%, 66.1%); ACM: 60.1% (50.1%, 68.7%); AM: 55.1% (45.1%, 64.0%). Analyzing response, risk category, and Rx revealed no association between baseline response and PFS (Baseline response &lt; VGPR, hazard ratio (HR): 1.21,95% CI: 0.97-1.52) or OS (baseline response &lt; VGPR, HR 1.02, 95%CI:0.70-1.48). High risk category had an adverse association for PFS (HR 1.62, 95% CI: 1.27-2.07) and OS (HR 1.51 (95% CI:1.01-2.26). Conclusions: In this analysis &lt; VGPR at baseline was not associated with PFS or OS. High-risk had an adverse association. Whether accomplishment of CR/minimal residual disease after AM, ACM,or TAM predicts for longer PFS and OS is the subject of ongoing analysis. Clinical trial information: NCT01109004.

Topic: Multiple Myeloma Research and Treatments
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Experimental Investigation of the Fire Resistance of Thin Hollow-Core Concrete Slabs with Simple Supports

This paper presents an experimental study on the fire resistance of relatively thin hollow-core concrete slabs with simple supports.A series of fire tests were conducted according to ISO 834 standard on nine hollow-core concrete slab specimens with thickness not exceeding 150 mm.The key parameters investigated are the heating duration, slab thickness and load ratio.Based on the test results, it has been found that the fireresistance ratings of all the tested specimens fall below the specified requirements in the current building regulations of Thailand.The level of concrete spalling on the fire-exposed surface increases with the heating duration.It has also been found that the fire resistance of thicker hollow-core concrete slabs may be lower, even when smaller values of maximum vertical deflection are observed during the heating period.Furthermore, a higher load ratio leads to a more rapid collapse of the tested specimen.The experimental results suggest the necessity of supplementary means of fire protection for these slabs in practical building construction.

Topic: Fire effects on concrete materials
Subfield: Civil and Structural Engineering
Field: Engineering
Domain: Physical Sciences
Utilizing Some Spices and Their Essential Oils As Flavoring Agents, And Preserving Agents For Biscuits

Spices and their essential oils have been used for centuries to enhance the flavor and aroma of various dishes. In this essay, we explore the utilization of some spices and their essential oils as flavoring agents and preserving agents for biscuits. The study aims to investigate the impact of incorporating spices such as cinnamon, ginger, and nutmeg, along with their essential oils, in biscuit recipes. The method includes experimenting with different concentrations of these spices and oils in biscuit formulations and evaluating the sensory properties, shelf-life, and antioxidant activity of the biscuits. The results suggest that the addition of spices and essential oils not only improves the flavor and aroma of biscuits but also extends their shelf-life due to the antimicrobial and antioxidant properties of these ingredients. The discussion delves into the potential applications of spices and essential oils in the food industry, highlighting their benefits in terms of flavor enhancement and preservation. In conclusion, the findings of this study support the use of spices and essential oils as natural flavoring and preserving agents in biscuits, offering a healthier and more sustainable alternative to synthetic additives.

Topic: Essential Oils and Antimicrobial Activity
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
ChemInform Abstract: Pyrrolidinopyridines in Palladium‐Catalyzed Allylic Substitutions — Conformation of the Ligand.

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Topic: Asymmetric Synthesis and Catalysis
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Developing a Textile Design Recommendation System According to Consumers' Sensibilities

Abstract Analysis of customers' sensibilities and preferences is an important strategy in a market that is becoming increasingly more customer oriented. The authors propose the Textile Design Recommendation System (TDRS) as an effective tool for focusing on customers' needs in the textile industry. The authors have developed a user interface tool that can suggest textile designs according to the users' needs. Collaborative filtering was adopted to search a textile design, and the performance of TDRS was tested according to three algorithms. This system may allow textile merchandisers to meet a consumer's needs more exactly and easily.

Topic: Color perception and design
Subfield: Social Psychology
Field: Psychology
Domain: Social Sciences
Gauguin's Homage to Honesty

WT hen one surveys Paul Gauguin's pictorial work, now conveniently available in the catalogue for the exhibition of 1988 [1], one may be struck by certain works distinguished by more than the simplified handling of shape and color, which they have in common with that of other leading painters of the late nineteenth century. These works also display certain spatial and compositional features that differ from the style of many other of Gauguin's works in which he conforms to the Western tradition prevailing since the Renaissance.

Topic: Art History and Market Analysis
Subfield: Visual Arts and Performing Arts
Field: Arts and Humanities
Domain: Social Sciences
Potential for nontuberculous mycobacteria proliferation in natural and engineered water systems due to climate change: A literature review

Nontuberculous mycobacterial (NTM) infections are costly, difficult to treat, and increasing in prevalence. Given this, there is a desire to understand the potential relationships between NTM in water sources and climate change stressors. To address this need, a critical literature review was performed. Connections were made between NTM fate and transport, climate change, engineering decisions, and societal changes, and uncertainties highlighted. Environmental conditions discussed with respect to NTM risk included changing temperature, humidity, salinity, rainfall, and extreme weather events. NTM risk was then considered under climate/societal scenarios described by Intergovernmental Panel on Climate Change (IPCC) scientists. Findings indicate that the resilience of NTM under a variety of environmental conditions (e.g., warm temperatures, eutrophication) may increase their net prevalence in water environments under climate change, increasing exposure. Water management decisions may also influence exposure to NTM as water scarcity is expected to result in increased reliance on reclaimed water. Water managers may control risk of exposure through innovative water treatment processes and equitable water management decisions, turning towards an integrated One Water approach to reduce and/or mitigate the impacts of de facto reuse. Future research recommendations are provided including studies into potential changes to NTM fate and transport in uniquely impacted climates (e.g., boreal regions), and investigations into the relative risk of managed aquifer recharge as compared to no action.

Topic: Mycobacterium research and diagnosis
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
GAMBARAN PELAKSANAAN PELAYANAN KESEHATAN PEDULI REMAJA (PKPR) DI PUSKESMAS DUPAK SURABAYA

Background: Adolescent health services is one of the government programs aimed at teenagers in Indonesia with the intention that teenagers have a comfortable place to grip or help deal with all sorts of teenage problems that are being faced. This PKPR is implemented in every Health Care. Purpose: the aims of this study was seen implementation PKPR in Dupak Health Care, Surabaya. Methods: This study was conducted at Dupak Health Care, Surabaya using qualitative descriptive research with observation method and in-depth interview at Head of Dupak Health Care Surabaya, holder of UKBM program (The Effort of Health Community Based Services) in Health Care, PKPR program holder, and some teenagers working area of Health Care. Results: The results and discussion in this journal that describes the implementation of health care services adolescents at Puskesmas Dupak Surabaya Health Center by adjusting the reference of National Standard PKPR 2014 and in line with previous similar research. Conclusion: There is a mismatch between the implementation of PKPR and the national standard of health care for adolescents that is influenced by various factors.

Topic: Adolescent Health and Behaviors
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
CCDC 990320: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: X-ray Diffraction in Crystallography
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
The complete mitochondrial genome of the hybrid sturgeon of <i>Huso dauricus</i> (♀) × <i>Acipenser schrenckii</i> (♂)

The complete mitochondrial genome sequence of the hybrid of <i>Huso dauricus</i> (♀) × <i>Acipenser schrenckii</i> (♂) is described in this study. The 16,693bp long circular molecule consisted of 13 protein-coding genes, 2 rRNA genes, 22 tRNA genes, and a control region, showed a typical vertebrate pattern. All genes were encoded on the heavy strain except for ND6 and eight tRNA genes. Base composition of the heavy strain was A(30.40%), T(24.19%), C(29.26%), G(16.16%), and with A + T bias of 54.59%. Comparing with the complete mitochondrial genome of its parents, the hybrid sturgeon of <i>Huso dauricus</i> (♀) × <i>Acipenser schrenckii</i> (♂) was consistent with a maternal inheritance. The complete mitogenome of the hybrid sturgeon of <i>Huso dauricus</i> (♀) × <i>Acipenser schrenckii</i> (♂) provides an important dataset for the exploration of mitochondrial inheritance mechanism.

Topic: Aquaculture Nutrition and Growth
Subfield: Aquatic Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences