jimnoneill/paper-to-field-training huggingface dataset:
Bilayer silicon oxide and silicon nitride thickness OOS elimination

In plasma enhanced chemical vapor deposition process, RF power is one of the dominant factors affecting the film deposition rate. The efficiency of RF power coupling is decided by the RF circuit, the plasma and the substrate. In this paper, we studied how the substrate electrical conductivity affects the RF power coupling efficiency and PECVD film deposition rate. For high resistivity wafers, wafer backside edge metallization increased its electrical conductivity hence increased the RF power coupling and increased the SiO and SiN film deposition rate. This impact was more on low frequency RF power than on high frequency RF power. In this work, we demonstrated SiO and SiN thickness out of specification on the InGaN LED (light emitting diodes) wafers was eliminated by removing the wafer edge backside metallization.

Topic: GaN-based semiconductor devices and materials
Subfield: Condensed Matter Physics
Field: Physics and Astronomy
Domain: Physical Sciences
ChemInform Abstract: Reaction of Salts of Hypophosphorous Acid with Alkyl Halides.

Abstract The potassium salt (I) of hypophosphorous acid reacts with the alkyl halides (II) to give the phosphonous acid esters (III), whereas the sodium salt (V) yields hypophosphorous acid (VI) and the alcohols (VII) under similar conditions.

Topic: Organophosphorus compounds synthesis
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Faber Method Classical Piano Learning In Purwacaraka Music School Purwokerto

Purwacaraka Purwokerto Music School is able to give birth to talented classical piano students so they can win various championships. From the observations, this is influenced by the use of the faber method in learning. This study aims to describe learning methods faber at Purwacaraka Purwokerto Music School. The research approach applied in this study is descriptive qualitative. Data collection techniques are carried out by observation, interview and document study. The results of this study indicate that the use of the faber method in classical piano learning in Purwacaraka Purwokerto Music School is only used at the beginner level (Grade Preparatory) and is an excellent method for learning at the beginner level because it uses books specifically designed for beginners with many bring up colorful images that make students imagine, so students understand learning material in their own way. The advantages of the faber method are that students get a strong foundation in reading beam notation, dynamics games and articulation in a score of songs played and this method is a very good method used as a basis for learning piano because it has material and theory that is emphasized to provide basic reference piano playing with piano playing techniques.

Topic: Sports and Physical Education Research
Subfield: Physical Therapy, Sports Therapy and Rehabilitation
Field: Health Professions
Domain: Health Sciences
Expression of Telomerase Reverse Transcriptase during the Malignant Transformation of Cadmium-Induced Cells

The objective of the present study was to investigate human telomerase reverse transcriptase (hTERT) mRNA and protein expressions during the cadmium chloride-induced malignant transformation of human bronchial epithelial (16HBE) cells.Fluorescence quantitative PCR (FQ-PCR) and Western blot analyses were performed to detect the hTERT mRNA and protein expressions in normal 16HBE cells, cadmium chloride-transformed 16HBE cells, and tumorigenic cells from nude mice inoculated with cadmium chloride-transformed 16HBE cells.Under the inner standard of GAPDH, the hTERT mRNA expression was significantly higher at different stages of malignant transformation (cadmium chloride-transformed 16HBE cells at passages 15 and 35 and tumorigenic cells from nude mice) than in normal 16HBE cells, and increased with the development of malignancy (P < 0.01).In addition, hTERT protein expression increased with the development of malignancy.These findings demonstrate that hTERT expression is related to cadmium chlorideinduced malignant transformation.Cadmium chloride-induced malignant transformation is involved in changes in the hTERT activity, and might be an early event in cadmium chloride-induced malignant transformation.

Topic: Microplastics and Plastic Pollution
Subfield: Pollution
Field: Environmental Science
Domain: Physical Sciences
Ocular abnormalities in patients with beta-thalassemia: a prospective study

&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Beta thalassemia is severe genetic blood disorder caused by mutation in the gene encoding for the beta chains of haemoglobin and individuals with beta thalassemia require life-long red blood cell transfusions to survive which leads to hemosiderosis and affects all the organs in the body including eyes. The study aims to study ocular manifestations in these children and its correlation with age and serum ferritin levels.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A descriptive cross-sectional study was done in government medical college Jammu in 2014-2015 on 67 BTM children. Children below 3 years of age and with pre-existing ocular abnormalities, infections were excluded from the study. Ocular examination was done for any major eye abnormality, congenital malformations or trauma. Retinal examination was done using direct and indirect ophthalmoscope, changes were recorded.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;47.76% of children belonging to the group: 5-10 years, while only 5.97%, i.e., 4 in number pertained to the age group: &amp;gt;15 years. Lens opacity was seen in 29.85% of children. 31 children showed changes in retinal activity, while decreased visual acuity was also observed in 17 children. Iris was significantly affected in children with serum ferritin &amp;gt;2500 ng/ml. Even greater lenticular changes and opacities were observed in children with higher serum ferritin levels (&amp;gt;4500 ng/ml).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;As life expectancy for beta-thalassemia patients extends, regular monitoring of the progression of disease and symptoms to detect early changes in their ocular system is recommended, to achieve a better quality of life for this patient group.&lt;/p&gt;

Topic: Hemoglobinopathies and Related Disorders
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
The influence of mineral nutrition and humic acids on the intensity of photosynthesis, as well as the yield and quality of seeds, roots, and aboveground phytomass of milk thistle <i>Silybum marianum</i> (L.) Gaertn. in marginal growing conditions

Abstract Milk thistle Silybum marianum (L.) Gaertn. is one of the most researched medicinal plants, but at the same time it belongs to crops with wide industry potential whose growth requirements for marginal agroecological conditions or the response to agronomic interventions has not yet been sufficiently studied. The aim of the present research was to verify the effect of mineral nutrition (NPK 200 kg/ha) and humic acids applied to the soil (HUMAC Agro 250 kg/ha) on the main biometric parameters and the intensity of photosynthesis of milk thistle grown under less favourable climatic conditions of the semi-cold and humid foothills in Central Europe. The highest seed yield was achieved with the NPK variant in terms of dry matter 0.534 t/ha, in the HUMAC Agro variant 0.254 t/ha and with the untreated control 0.087 t/ha. The soil before the trial establishment was characterised by low nutrient content. The use of mineral fertiliser on NPK treatment eliminated the influence of low PK nutrients content of the soil, influencing the crop growth and yield/quality, while no doses of NPK were used on the HUMAC Agro variant and the untreated control. For both of the two sequences created (temperature and light), the highest photosynthesis rate was measured on untreated control (20.115 and 12.386 mmol/m 2 /s 1 ), markedly lower on HUMAC Agro (16.386 and 9.653 mmol/m 2 /s 1 ) – and the lowest on the NPK (10.933 and 7.813 mmol/m 2 /s 1 , respectively), in inverse proportion to the crop yield. Therefore, the size of the leaf area of the crop was decisive for the increased crop yield. The polynomial trend line of the photosynthesis rate according to the temperature sequence shows the photosynthesis rate and the torrential decrease by temperature increasing on untreated control compared with both treated variants. Both of these threats, mineral nutrition and use of humic preparations to soil, although they reduce the photosynthesis rate, have a wide range of complex effects that provide an opportunity to optimise the growth and yield of milk thistle. Ideally, the mineral nutrition and humic preparations should be used in combination with the crop of milk thistle for medicinal and energy purposes.

Topic: Silymarin and Mushroom Poisoning
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Real‐world emetic risk of chemotherapy and the corresponding antiemetic therapy in Japan: A study based on a nationwide database

Abstract Background Chemotherapy‐induced nausea and vomiting (CINV) is a major concern of patients with cancer, leading to suboptimal treatment. Aim This study assessed the emetic risk associated with intravenous and oral chemotherapy and the prophylactic antiemetic drugs by cancer type in a real‐world setting. Methods and Results We used the health services utilisation data for patients with cancer diagnosed in 2016. Patients aged at least 20 years at the time of diagnosis and who started their first course of chemotherapy were included. The emetic risk of chemotherapy was determined according to the cancer type and was classified based on clinical practice guidelines. The prescription of antiemetic drugs was assessed. Overall, 172 133 patients were evaluated, of whom 121 103 (70.4%) received intravenous chemotherapy. High‐emetic‐risk chemotherapy (HEC) was prescribed in 46 458 (27.0%) patients. HEC was prescribed most for patients with oesophageal cancer (80.3%), followed by malignant lymphoma (60.2%) and breast cancer (53.8%). Moderate‐emetic‐risk chemotherapy (MEC) was prescribed in 60 528 (35.2%) patients and was mostly prescribed for small cell lung cancer (59.9%). Meanwhile, more than 50% of the chemotherapy prescribed for patients with gastric, colorectal, and pancreatic cancer was low‐emetic‐risk chemotherapy. HEC was accompanied by three‐drug antiemetic prophylaxis in more than 90% of patients with small cell lung, non‐small cell lung, breast, and oesophageal cancer, whereas only 13.5% of patients with malignant lymphoma were administered CHOP (cyclophosphamide, doxorubicin, vincristine sulphate, and prednisolone) with prophylaxis. Conclusion The risk of CINV differs with cancer type. HEC was less prescribed compared with MEC. Most patients received the recommended anti‐emetic prophylaxis.

Topic: Nausea and vomiting management
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Production technology of late Roman decorated tableware from the Vesuvius environs: Evidence from Pollena Trocchia (Campania region, Italy)

Abstract The northern slope of Mt. Vesuvius contains some interesting archaeological sites, including the site discovered in the town of Pollena Trocchia , where the remains, dated to between the 79 and 472 CE eruptions, document the transition from the Roman to late Roman cultural and socioeconomic settings. Profound changes occurred in this time interval, which can be inferred from changes in the ceramic manufacturing processes. Common wares, as the most widespread ceramic class in the archaeological record, are a useful example that illustrates this technological transformation. Seventeen samples of tableware, distinguished into three ceramic classes according to the method of slip application (i.e., Slipped Ware, Painted Ware “a straccio,” and Painted Ware), were analyzed. The results highlight the use of high‐CaO clayey raw materials compositionally similar to Apennine clayey deposits. The clay bodies were occasionally tempered with sandy‐silt materials composed of volcanic grains with lesser amounts of siliciclastic fragments. Firing temperatures ranged from 800 to 950°C, as suggested by quantitative X‐ray powder diffraction and microstructural analyses combined with colorimetric measurements of the ceramic bodies. Micro‐Raman analyses performed on slips revealed the use of ochre for decorating the vessels; it was applied in a different way, representing an actual technological change.

Topic: Cultural Heritage Materials Analysis
Subfield: Archeology
Field: Arts and Humanities
Domain: Social Sciences
Role of Treponema Reiter in Modern Serology of Syphilis

Wassermann and Ficker (1922) succeeded in isolating seven virulent strains of Treponema pallidum from the serum from eighty to ninety primary chancres.One strain, B:,, was kept and * For instance, Gelperin (1951) was unable to protect rabbits against syphilis by immunization with Reiter's spirochaetae.

Topic: Syphilis Diagnosis and Treatment
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Redesign of technological tools to increase the level of learning of CIBERTEC students

RESUMENEn el presente trabajo de investigación se diagnosticó y determinó la influencia del rediseño de las herramientas tecnológicas de los cursos de Blended en el grado de aprendizaje de los estudiantes matriculados en los cursos Blended de la Línea de Tecnología del Instituto Superior Tecnológico Privado Cibertec de la sede Trujillo.En este trabajo se utilizaron los indicadores Diseño Instruccional, Modelo Pedagógico, Curso, Herramienta Virtual

Topic: Foreign Language Teaching Methods
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Impact of Light Intensity on Antioxidant Activity of Tropical Microalgae

Twelve microalgae species isolated in tropical lagoons of New Caledonia were screened as a new source of antioxidants. Microalgae were cultivated at two light intensities to investigate their influence on antioxidant capacity. To assess antioxidant property of microalgae extracts, four assays with different modes of action were used: 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2’-azino-bis (3-éthylbenzothiazoline-6-sulphonique) (ABTS), oxygen radical absorbance capacity (ORAC), and thiobabituric acid reactive substances (TBARS). This screening was coupled to pigment analysis to link antioxidant activity and carotenoid content. The results showed that none of the microalgae studied can scavenge DPPH and ABTS radicals, but Chaetoceros sp., Nephroselmis sp., and Nitzschia A sp. have the capacity to scavenge peroxyl radical (ORAC) and Tetraselmis sp., Nitzschia A sp., and Nephroselmis sp. can inhibit lipid peroxidation (TBARS). Carotenoid composition is typical of the studied microalgae and highlight the siphonaxanthin, detected in Nephroselmis sp., as a pigment of interest. It was found that xanthophylls were the major contributors to the peroxyl radical scavenging capacity measured with ORAC assay, but there was no link between carotenoids and inhibition of lipid peroxidation measured with TBARS assay. In addition, the results showed that light intensity has a strong influence on antioxidant capacity of microalgae: Overall, antioxidant activities measured with ORAC assay are better in high light intensity whereas antioxidant activities measured with TBARS assay are better in low light intensity. It suggests that different antioxidant compounds production is related to light intensity.

Topic: Algal biology and biofuel production
Subfield: Renewable Energy, Sustainability and the Environment
Field: Energy
Domain: Physical Sciences
TAVI Program in a Center Without On-Site Cardiac Surgical Department

Background: Aortic stenosis (AS) is the most common valvular heart disease, associated with poor outcomes if left untreated. Current guidelines recommend that transcatheter aortic valve implantation (TAVI) procedures be performed in hospitals with an on-site cardiac surgery unit due to potential complications requiring surgical intervention. This study aims to evaluate the feasibility and clinical outcomes of implementing a TAVI program at a cardiology department without an on-site cardiac surgery department, in collaboration with a remote hospital for surgical backup. Methods: The TAVI program involved pre- and post-procedural evaluations conducted at Meir Medical Center (Kfar Saba, Israel) with a remote surgical team available. The study population included 149 consecutive patients with severe aortic stenosis treated at the Meir valve clinic between November 2019 and December 2023. Procedures were performed by the center&amp;#039;s interventional cardiology team. Results: The mean age of the 149 patients was 80 ± 6 years, and 75 (50%) were female. The average STS score was 4.3 and the EuroSCORE II was 3.1. Among the patients, 68 (45%) were classified as New York Heart Association (NYHA) class III-IV. Valve types used included Acurate-neo 2 (57 patients, 38%), Sapien-3 (43 patients, 28%), Evolut-PRO (41 patients, 27%), and Navitor (7 patients, 4%). There were no cases of moderate to severe paravalvular leak, no elevated post-implantation gradients, and no need for urgent cardiac surgery. One case of valve embolization was successfully managed percutaneously during the procedure. In-hospital follow-up revealed no deaths and only one major vascular complication. At one-year follow-up, six patients had died, with only one death attributed to cardiac causes. Conclusions: This study demonstrates that the transfemoral TAVI procedure can be safely and effectively performed in a cardiology department without an on-site cardiac surgery unit, provided there is collaboration with a remote surgical center. These findings suggest that expanding TAVI programs to centers without on-site cardiac surgery could increase access to this life-saving treatment for aortic stenosis.

Topic: Cardiac Valve Diseases and Treatments
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
An RT-PCR-based multi-gene prognostic signature predicts distant metastasis of node negative, ER positive breast cancer from FFPE sections

506 Background: Gene expression profiles have been shown to predict distant metastasis risk in breast cancer patients. For routine medical practice, molecular prognostic tests need to be able to quantify metastasis risk with readily available samples and optimally employ regulatory-approved platforms. Methods: 142 early stage, N-, ER+, untreated breast cancer patients were chosen. Mean age was 61.8 (31 - 89) yrs with 72% &gt; 55 yrs. RNA was isolated from 4×10 μm FFPE sections. Using real-time RT-PCR, 200 genes selected from van ‘t Veer et al, Dai et al, Paik et al and additional candidate genes were profiled. Primary endpoint was distant metastasis free survival. A prognostic signature was identified using semi-supervised principal component method. Metastasis score (MS) was calculated from gene expression levels. Results: We identified a unique 15-gene prognostic signature and 3 normalization genes. Probability of metastasis for any time period can be calculated from MS and was evaluated for 2, 5, and 10 yrs. Using median of MS to stratify patients, the high-risk group had a hazard ratio (HR) of 4.1 (95%CI 1.77–9.54, p = 0.001) vs. the low-risk group. 5-yr and 10-yr metastasis free survival rates (std. error) were 0.76 (0.053) and 0.62 (0.064) in the high-risk group and 0.96 (0.025) and 0.90 (0.038) in the low-risk group. Multivariate Cox regression analyses indicated that molecular signature had independent prognostic value with HR of 2.97 (95%CI 1.17 - 7.52, p = 0.022) after adjusting for age, tumor size and grade. Molecular signature was more prognostic in the low-grade subgroup (HR = 6.85, 95%CI 1.81–25.88) than an unstratified analysis. AUC at 5 yr was 0.65 and 0.60 for molecular signature and Adjuvant Online (AO) respectively. The prognosticator combining both had AUC of 0.67. 10-yr metastasis probabilities from MS and AO have low correlation (R 2 =0.17). Conclusions: A prognostic signature based upon mRNA expression of 15 genes has been identified using FFPE sections with RT-PCR for early stage, N-, ER+ patients. Metastasis score that quantifies distant metastasis risk for any time period, not confounded with any treatment effect, can help clinicians and patients to choose among different therapeutic options. (Lau and Wang contribute equally) [Table: see text]

Topic: Cancer Genomics and Diagnostics
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Anterior Vented Gas Forced Infusion System of the Accurus Surgical System in Phakonit

Journal of Cataract & Refractive Surgery 30(4):p 933-935, April 2004. | DOI: 10.1016/j.jcrs.2004.02.062

Topic: Intraocular Surgery and Lenses
Subfield: Ophthalmology
Field: Medicine
Domain: Health Sciences
Selective maintenance modeling for industrial systems

In many industrial environments, systems are required to perform a sequence of operations (or missions) with finite breaks between each operation. During these breaks, it may be advantageous to perform repair on some of the system’s components. However, it may be impossible to perform all desirable maintenance activities prior to the beginning of the next mission due to limitations on maintenance resources. In this paper, a mathematical programming framework is established for assisting decision‐makers in determining the optimal subset of maintenance activities to perform prior to beginning the next mission. This decision‐making process is referred to as selective maintenance. The selective maintenance models presented allow the decision‐maker to consider limitations on maintenance time and budget, as well as the reliability of the system. Selective maintenance is an open research area that is consistent with the modern industrial objective of performing more intelligent and efficient maintenance.

Topic: Reliability and Maintenance Optimization
Subfield: Safety, Risk, Reliability and Quality
Field: Engineering
Domain: Physical Sciences
A comparison of dressings in the management of surgical abdominal wounds

This prospective randomised trial compared the performance of three dressing protocols in the management of 36 dehisced surgical abdominal wounds: a standard alginate; a gauze moistened with sodium hypochlorite (0.05%); and a combine dressing pad. Outcomes assessed were: healing time (cm2 per day and cm3 per day), patient comfort (pain and satisfaction) and cost. There were no statistically significant differences in healing rates between the three groups but there was a trend for the combine dressing pad protocol to produce a greater reduction in wound area. The combine dressing pad protocol performed well when compared with the calcium alginate in terms of healing time, patient comfort and cost. Maximum pain was significantly greater (p=0.011) and satisfaction significantly lower among patients who received the sodium hypochlorite protocol. Costs during the in-patient phase were also substantially higher for the sodium hypochlorite protocol. Trial results support the view that sodium hypochlorite dressing protocols for surgical wounds should be abandoned.

Topic: Abdominal Surgery and Complications
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences