jimnoneill/paper-to-field-training huggingface dataset:
Towards Design Guidelines for IoT Applications considering Elderly Users

The Internet of Things (IoT) has become a relevant topic in Human-Computer Interaction (HCI), as it has introduced a new technological paradigm capable of transforming how people experience and use technology. Despite the significant growth in the number of connected devices in IoT scenarios, not all users have the same ability to benefit from this technology. Population aging is a global phenomenon that occurs at an accelerated pace. Thus, elderly users (60+) also must be able to use technologies like IoT. In this regard, design guidelines play a crucial role. Therefore, in this paper, we have established a set of guidelines to support designers and developers in constructing IoT solutions, focusing on elderly users and considering requirements such as usability and accessibility. The guidelines were created following several steps, namely: literature review, interviews with elderly users and companies, expert evaluation steps, and conducting a proof of concept. The guidelines were subjected to cycles of evaluations and refinements that resulted in new versions of the set. The results of the evaluations showed that the current version of the guidelines (version 2.1) supports the development of IoT applications since developers, when using them, consider accessibility and usability issues more effectively for elders.

Topic: Technology Use by Older Adults
Subfield: Demography
Field: Social Sciences
Domain: Social Sciences
Outcome of surgical treatment of hilar cholangiocarcinoma: a special reference to postoperative morbidity and mortality

Abstract Background/purpose Radical resection for hilar cholangiocarcinoma is still associated with significant morbidity and mortality. The aim of this study was to analyze short‐term surgical outcomes and to validate our strategies, including preoperative management and selection of operative procedure. Methods We surgically treated 146 consecutive patients with hilar cholangiocarcinoma with a management strategy consisting of preoperative biliary drainage, portal vein embolization, and selection of operative procedure based on tumor extension and hepatic reserve. Major hepatectomy was conducted in 126 patients, and caudate lobectomy or hilar bile duct resection in 20 patients. Results The overall 5‐year survival rate was 35.5%, with overall in‐hospital mortality and morbidity rates of 3.4 and 44%, respectively. Hyperbilirubinemia (total bilirubin &gt;5 mg/dL, persisted for &gt;7 postoperative days) and liver abscess were the most frequent complications. Five among 9 patients with liver failure (total bilirubin &gt;10 mg/dL) encountered in‐hospital mortality. Four out of 5 mortality patients had suffered circulatory impairment of the remnant liver due to other complications. Multivariate analysis revealed that operative time is a single independent significant predictive factor (odds ratio, 1.005; 95% confidence interval, 1.000–1.010, P = 0.04) for postoperative complications. Conclusions Aggressive resection for hilar cholangiocarcinoma, performed in accordance with strict management strategy, achieved acceptably low mortality. Prolonged operative time was a risk for morbidity following hepatobiliary resection.

Topic: Cholangiocarcinoma and Gallbladder Cancer Studies
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Management of Delayed Eruption in Permanent Incisor Following Intrusion Injury of Primary Dentition: A Case Report

Jawza H Alfarraj,1 Faisal Alsaif,2 Sama A Alsaad3 1Pediatric Dentistry Department, King Fahad Medical City, Riyadh, Saudi Arabia; 2General Dentist, Private Practice, Riyadh, Saudi Arabia; 3Pediatric Dentistry Department, King Saud Medical City, Riyadh, Saudi ArabiaCorrespondence: Jawza H Alfarraj, Tel +966509948859, Email Jalfarraj@kfmc.med.saAbstract: This article describes the clinical management of delayed eruption of the upper left permanent central incisor of an eight-year-old child with a history of overlooked intrusive trauma to the primary maxillary incisors. Initial conservative management involved simple extraction of the over-retained upper right primary left incisor. At the recall visit, the decision was made to expose permanent incisors surgically aiming to facilitate its eruption. Two years later, the upper right central and lateral incisors have been erupted into the oral cavity, improving patient aesthetics. This case report aims to demonstrate the clinical diagnosis and intervention for delayed eruption of maxillary permanent central incisor as a consequence of an overlooked intrusive trauma in the primary dentition. Additionally, to emphasize the importance of periodic radiographic examination in monitoring the sequence of eruption in mixed dentition.Keywords: dental trauma, unerupted, delayed eruption, pediatric

Topic: Dental Trauma and Treatments
Subfield: Emergency Medical Services
Field: Health Professions
Domain: Health Sciences
The symptom as metaphor in Lacan's theory of the unconscious.

An analysis of Freud's forgetting of the name Signorelli provides a framework for an explication of some central concepts in Lacan's theory of the unconscious. The parapraxis is viewed as a symptom which is structured like a metaphor. The creation of a symptom during the process of repression produces a gap in conscious discourse. The analysis of such symptoms provides evidence for Lacan's assertion that the unconscious is structured like a language.

Topic: Psychoanalysis, Philosophy, and Politics
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
THE CONSEQUENCES OF SOFT REPRESSION*

This article examines the consequences of soft repression on social movement activists. By drawing on activists’ perceptions, we develop a multilayered analytical framework that captures the experienced effects of soft repression at the individual, organizational, and movement levels. Our results show that soft repression—in particular, labeling, and stigmatization—primarily affect the individual level by triggering self-policing and self-control. By introducing a model that incorporates several radical social movement organizations, we also show how labeling and stigmatization affect different radical groups in different ways. These measures sometimes fail to demobilize the primary targets of the repressive actions, the most militant and clandestine groups. Instead, the demobilizing effects seem most evident in organizations that mobilize openly and inclusively. Our analysis is based on in-depth interviews with activists from the radical left-libertarian movement (RLLM) in Sweden, most of which have been active in organizations labeled as “violence-affirming extremists” by the Swedish government.

Topic: Terrorism, Counterterrorism, and Political Violence
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
pL0R-LacZ v1

Name: pL0R-LacZ Description: a L0 receiver vector which can be used for domestication using SapI-mediated restriction ligation or Gibson assembly. Contains lacZ for blue/white colony screening. Requires X-GAL, IPTG optional depending on E. coli strain. Level 0 Overhangs: Special (cuts into BsaI sites) Length: 2646 Antibiotic selection: Spectynomycin Other info: pMB1 ori Characterisation: ++++ (substantial), works as expected. Primers: U1FCATTACTCGCATCCATTCTCU1RGAGACGAGACGAGACAGCCTUXFCCAGGATACATAGATTACCAUXRGGTGGAAGGGCTCGGAGTTGL0FTGGGCTGCCTGTATCGAGTGL0RGCTGGCCTTTTGCTCACA L0 F works great for sequencing. Submitter: Bernardo Pollak Cloned by: Bernardo Pollak Availability: Upon request at the Pollak/Dupont/Federici labs at the moment and will be available soon from Addgene.

Topic: Molecular Biology Techniques and Applications
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Comparative efficacy and safety of 4 atypical antipsychotics augmentation treatment for major depressive disorder in adults: A systematic review and network meta-analysis

Background: Atypical antipsychotic (AAP) augmentation is an alternative strategy for patients with major depressive disorder (MDD) who had an inadequate response to antidepressant therapy (ADT). We aimed to compare and rank the efficacy and safety of 4 AAPs in the adjuvant treatment of MDD. Methods: We searched randomized controlled trials (RCTs) published and unpublished from the date of databases and clinical trial websites inception to April 30, 2023. The evidence risk of bias (RoB) and certainty are assessed using the Cochrane bias risk tool and grading of recommendations assessment, development, and evaluation (GRADE) framework, respectively. Using network meta-analysis, we estimated summary risk ratios (RRs) or standardized mean difference (SMD) based on the random effects model. Results: 56 eligible studies comprising 11448 participants were included. In terms of primary efficacy outcome, compared with placebo (PBO), all AAPs had significant efficacy (SMD = −0.40; 95% CI, −0.68 to −0.12 for quetiapine (QTP); −0.35, −0.59 to −0.11 for olanzapine (OLA); −0.28, −0.47 to −0.09 for aripiprazole (ARI) and −0.25, −0.42 to −0.07 for brexpiprazole (BRE), respectively). In terms of acceptability, no significant difference was found, either agents versus agents or agents versus PBO. In terms of tolerability, compared with the PBO, QTP (RR = 0.24; 95% CI,0.11–0.53), OLA (0.30,0.10–0.55), ARI (0.39,0.22–0.69), and BRE (0.37,0.18–0.75) were significantly less well tolerated. 8 (14.2%) of 56 trials were assessed as low RoB, 38 (67.9%) trials had moderate RoB, and 10 (17.9%) had high RoB; By the GRADE, the certainty of most evidence was low or very low. Conclusion: Adjuvant AAPs had significant efficacy compared with PBO, but treatment decisions must be made to balance the risks and benefits.

Topic: Treatment of Major Depression
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Clean Development Mechanism (CDM) – Based Development of Grid-Connected Rice Husk-Fuelled Bio-Power Plants in Mekong Delta, Vietnam

The research is designed for developing the pilot small-scale clean development mechanism bundled project activities in Vietnam electricity/ energy sector. Its overall purpose is to assess the potential of rice husk - fuelled bio-power development projects in Mekong delta. Based on estimating the electricity potential of a bundle of rice husk-fuelled bio-power development projects in Mekong delta with the capacity of 11 MW per project, assessing their CO2 emission reductions (CERs) and CER credits, calculating and comparing their financial indices (NPV, B/C, IRR) in two cases: W/O CDM and W/CDM, the research expects to establish a rice husk energy balance flowchart for the whole Mekong delta in the year 2021 and recommend policies to use for bio-power generation the unused rice husk that is dumped and discharged from local paddy milling centers into rivers and canals, as well as, to put forward a safe and environmentally friendly solution to minimize thoroughly the current serious pollution of rivers and canals in Mekong delta with the increasing unused rice husk quantity in the context is where the sea level rise phenomenon is the strongest in the world .

Topic: Water-Energy-Food Nexus Studies
Subfield: Water Science and Technology
Field: Environmental Science
Domain: Physical Sciences
Bi-Directional Pseudo-Three-Dimensional Network for Video Frame Interpolation

Recent video frame interpolation methods have employed the curvilinear motion model to accommodate nonlinear motion among frames. The effectiveness of such model often hinges on motion estimation and occlusion detection, and therefore is greatly challenged when these methods are used to handle dynamic scenes that contain complex motions and occlusions. We address the challenges by proposing a bi-directional pseudo-three-dimensional network to exploit the correlation between motion estimation and depth-related occlusion estimation that considers the third dimension: depth. Specifically, the network exploits the correlation by learning shared multi-scale spatiotemporal representations, and by coupling the estimations, in both the past and future directions, to synthesize intermediate frames through a bi-directional pseudo-three-dimensional warping layer, where adaptive convolution kernels are estimated progressively from the coalescence of motion and depth-related occlusion estimations across multiple scales to acquire nonlocal and adaptive neighborhoods. The proposed network utilizes a novel multi-task collaborative learning strategy, which facilitates the supervised learning of video frame interpolation using complementary self-supervisory signals from motion and depth-related occlusion estimations. Across various benchmark datasets, the proposed method outperforms state-of-the-art methods in terms of accuracy, model size and runtime performance.

Topic: Advanced Vision and Imaging
Subfield: Computer Vision and Pattern Recognition
Field: Computer Science
Domain: Physical Sciences
SUMMARY Although

anthropometric dimensions eval-uate the health of newborns, there is not enough information in this field in Iran. This study was undertaken on female newborns from Arak to determine the range of their head and face dimensions in comparison with other subgroups of the Iranian population. The means and SD of cephalic and prosopic indices were 81.5 ± 4 and 94.9 ± 8.1 respec-tively. The dominant type of cephalic index was mesocephalic and the rarest one was dolichocephalic. The dominant and rare types of faces were hypereuryprosopic and hyperlep-toprosopic. The means of head length did not show statistically significance in the Arak, Turkmen and Fars populations, while head breadth was higher for the Arak individuals in comparison with Fars (P&amp;lt;0.01) and Turkmen (P&amp;lt;0.002). Although the mean of head cir-cumference for the Arak was higher, there was no statistical significance in comparison with the Kurd, Turkmen and Fars racial subgroups. Morphological classification of the head showed that there were no statistical signifi-cant differences between Arak and Fars. The percent of the brachyocephalic type for Arak and Fars subgroup was statistically higher than that for Turkmen (P&amp;lt;0.02), while the dolichocephalic type was lower for Arak and Fars (P&amp;lt;0.02) Morphological classification of the face showed that there were no statistical significant differences between Arak and Fars. The most marked differences were observed in the face shapes of the Arak and Fars in com-parison with Turkmen. The types of head and face of the female Arak newborns differ some-what from those observed in populations from other parts of Iran. However, the cephalomet-ric evaluation indicates that the craniofacial features of Arak newborns are more similar to the Fars racial subgroup living in Iran. In sum, it can be said that across the racial differ-ences, socio-ecological factors such as colder climates and nutrition may influence craniofa-cial parameters.

Topic: Forensic Anthropology and Bioarchaeology Studies
Subfield: Archeology
Field: Arts and Humanities
Domain: Social Sciences
SNAI1 is a prognostic biomarker and correlated with immune infiltrates in gastrointestinal cancers

Epithelial-mesenchymal transition (EMT)-related genes play an important role in immunosuppression. However, the correlations of EMT-related genes to prognosis and tumor-infiltrating lymphocytes in different cancers remain unclear. TCGA, GEO databases were used to analyze the expression, prognosis, and immune infiltration of EMT markers in cancer. RT-qPCR, immunohistochemistry, and western blot were used to analysis the expression and prognosis of SNAI1 in gastrointestinal cancers. High SNAI1 expression was closely related with poorer overall survival in gastrointestinal cancers in TCGA cohort. High SNAI1 expression was closely related with poorer overall survival in gastrointestinal cancers, and was validated in GEO database. Simultaneously, high expression of SNAI1 correlates with clinical relevance of gastric cancer. Moreover, SNAI1 expression was associated with tumor-infiltrating immune cells in gastrointestinal cancers. In addition, RT-qPCR, immunohistochemistry, and western blot showed SNAI1 expression was higher in gastrointestinal cancers compared to the normal tissues. Finally, high SNAI1 expression was closely related with poorer overall survival and correlates with clinical relevance of gastrointestinal cancers in an independent validation cohort. In summary, the results approaches to suggest that SNAI1 can be used as a prognostic biomarker for determining prognosis and immune infiltration in gastrointestinal cancers.

Topic: Cancer Immunotherapy and Biomarkers
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Additional file 1: of Risk-conscious correction of batch effects: maximising information extraction from high-throughput genomic datasets

Contains additional information and discussion on gPCA (Reese et al., 2013). Table S1. Demonstrates the inverse proportionality between gPCA p-value and the associated â deltaâ score, reflecting unadjusted relative magnitude of batch effects (Reese et al., 2013). The table shows the scores for all three datasets. Figure S1. Contains an Illustration to further help interpret gPCA p-value vs preserved data variance plots. (DOCX 60 kb)

Topic: Gene expression and cancer classification
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Contributions to the taxonomy of the Brazilian Leurus Townes, 1946 (Hymenoptera: Ichneumonidae, Metopiinae)

Leurus Townes, 1946 is a small genus of Metopiinae (Hymenoptera: Ichneumonidae), consisting of 13 described species distributed in the Neotropics and the Nearctic region. The present work aims to contribute to the taxonomic knowledge of Leurus in Brazil. A total of 109 specimens were identified and 15 literature records were analyzed. The genus geographical occurrence was evaluated according to data obtained from the literature and labels of analyzed specimens. Five species of Leurus were identified for the Brazilian fauna: L. angustignathus, L. caeruliventris, L. discus, L. gracius and L. nostrus. New municipality records of occurrence were made for L. angustignathus in the state of São Paulo, L. caeruliventris in the states of Bahia, Distrito Federal, Mato Grosso, Mato Grosso do Sul, Minas Gerais, Paraná, Piauí and Rondônia; for, L. discus in the state of Alagoas and São Paulo, and L. gracius in the state of Minas Gerais, Rio de Janeiro, and São Paulo. Females of L. angustignathus and L. gracius were described for the first time in the present study. The genitalia of males of L. caeruliventris, L. discus and L. gracius were described and illustrated for the first time.

Topic: Hymenoptera taxonomy and phylogeny
Subfield: Ecology, Evolution, Behavior and Systematics
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Less is More: Optimizing Function Calling for LLM Execution on Edge Devices

The advanced function-calling capabilities of foundation models open up new possibilities for deploying agents to perform complex API tasks. However, managing large amounts of data and interacting with numerous APIs makes function calling hardware-intensive and costly, especially on edge devices. Current Large Language Models (LLMs) struggle with function calling at the edge because they cannot handle complex inputs or manage multiple tools effectively. This results in low task-completion accuracy, increased delays, and higher power consumption. In this work, we introduce Less-is-More, a novel fine-tuning-free function-calling scheme for dynamic tool selection. Our approach is based on the key insight that selectively reducing the number of tools available to LLMs significantly improves their function-calling performance, execution time, and power efficiency on edge devices. Experimental results with state-of-the-art LLMs on edge hardware show agentic success rate improvements, with execution time reduced by up to 70% and power consumption by up to 40%.

Topic: Advancements in Semiconductor Devices and Circuit Design
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Lithium in Soils and Plants of Western Transbaikalia

The content of lithium in soil-forming rocks, soils, and plants of forest-steppe, steppe, and dry-steppe landscapes of Transbaikalia has been studied. The mean Li content is 1.1 times higher in soil-forming rocks than the natural abundance (clarke) of this element in the Earth crust and is 1.1–1.3 times higher in the studied soils as compared to the clarke of this element in soils of the world. The Li content in soils is closely related to its amount in soil-forming rocks, while its correlation with the soil humus and Li concentration in plants is absent. Spatial and vertical distribution patterns of Li in soils of the studied landscapes are described. According to the coefficients of the biological uptake of Li by steppe, meadow, and agrogenic cenoses from soils (1.2–2.4), this element is assigned to the group of moderate accumulation. The mean Li content in steppe and meadow plants and crops is 1.3–2.3 times higher than its average content in terrestrial vegetation. Lithium concentrations reach toxic values (5–15 mg/kg) in plants of eight test plots in meadow cenoses. The accumulation of Li per unit area in the meadow vegetation is 10.5 times higher than that in the dry-steppe vegetation.

Topic: Soil and Environmental Studies
Subfield: Soil Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
5-HT activates nitric oxide-generating neurons to stimulate chloride secretion in guinea pig distal colon

The participation of nitric oxide (NO) in serotonin (5-hydroxytryptamine; 5-HT)-evoked chloride secretion in guinea pig distal colon was examined. Submucosal/mucosal segments were mounted in Ussing flux chambers, and an increase in short-circuit current ( I sc ) was used as an index of secretion. Addition of 5-HT to the serosal side produced a concentration-dependent (10 −7 –10 −5 M) increase in I sc caused by chloride secretion. N G -nitro-l-arginine (l-NNA) significantly reduced the 5-HT-evoked early (P-1) and late (P-2) responses to 61.1 and 70.6% of control, respectively. Neurally evoked response was also inhibited by l-NNA. The NO donor sodium nitroprusside (SNP, 10 −4 M) increased basal I sc mainly because of chloride secretion. The SNP-evoked response was significantly reduced by tetrodotoxin but was unchanged by atropine or indomethacin. These results suggest that the 5-HT-evoked increase in I sc is associated with an NO-generating mechanism. Atropine significantly reduced the 5-HT (10 −5 M)-evoked P-1 and P-2 responses to 71.8 and 19.7% of control, respectively. Simultaneous application of atropine andl-NNA further decreased the 5-HT-evoked responses more than either drug alone; application ofl-NNA and atropine decreased the 5-HT-evoked P-1 and P-2 responses to 68.5 and 39.2% of atropine-treated tissues, respectively. These results suggest that noncholinergic components of P-1 and P-2 responses are 71.8 and 19.7% of control, respectively, and that NO components of P-1 and P-2 responses are 32 and 61%, respectively, of the noncholinergic component of the 5-HT-evoked responses. The results provide evidence that NO may participate as a noncholinergic mediator of 5-HT-evoked chloride secretion in guinea pig distal colon.

Topic: Neuropeptides and Animal Physiology
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences