jimnoneill/paper-to-field-training huggingface dataset:
Collaborative and Content-Based Filtering Hybrid Method on Tourism Recommender System to Promote Less Explored Areas

The COVID-19 pandemic has significantly impacted various areas of life, including tourism. Currently, the tourism sector is starting to recover and start its activities. However, several tourist attractions have not been explored, thus making visitors less aware of information about these tours. This affects the number of tourist visits. Therefore, there is a need of an information technology approach to promote tourism objects, including a tourist recommendation system. This study proposed a hybrid recommendation system incorporating collaborative and content based filtering. This model is proven to be able to produce good rating predictions on a recommendation system. This hybrid method uses a linear combination by calculating the rating matrix and user profile as the first step in providing rating predictions. Collaborative filtering is calculated using the cosine similarity algorithm and weighted sum algorithm, while the content-based filtering method is performed by calculating the weight of each available feature. We apply this model to the Palembang tourism dataset to the the website. This system recommends existing historical tourist attractions based on visitor criteria. The results show the existing data's effective, efficient, and accurate results. The calculation result that the rating prediction using the hybrid method is 3.203. In addition, this method can also help overcome existing cold start problems.

Topic: Digital Marketing and Social Media
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Do feral pigs increase soil erosion? A monsoonal northern Australia case study

Abstract Animals are recognised biological agents that can turn over large amounts of soil, influence soil structure and composition and may allow soil to more easily erode. Feeding activities of feral pigs ( Sus scrofa ) are known to produce considerable soil disturbance. Here, pig disturbance, together with soil erosion and deposition patterns, are quantified along two hillslope transects in northern Australia over 10 years. Annual disturbance by pigs was ~1% of surface area. The erosion rate was low with a range of 0.008–0.13 mm year −1 . Both transects had similar hillslope profiles, vegetation patterns and similar appearance. There was a greater number of pig disturbances, area and mass of material disturbed by pigs for one transect compared to the other moving downslope. However, for the second transect, the number of disturbances significantly decreased moving downslope while the mass of material exhumed remained relatively constant along the hillslope. For the first transect, this suggests that the greater number of pig digs moving downslope reduces hillslope connectivity and therefore reduces erosion. That is, the greater the amount of disturbance by pigs, the less erosion. The pig digs produce a pit and a mound with the material diffusing locally and the pit capturing material from upslope reducing hillslope connectivity. These pits have been observed to last many years. A control on pig disturbance was likely to be rock content. The average surface rock content of the two transects was significantly different (9% and 20%, respectively) and with the higher rock content reducing pig disturbance and erosion for the second transect. The bio geomorphic influence that pigs represent in the landscape for biogeochemical cycling requires ongoing investigation.

Topic: Soil erosion and sediment transport
Subfield: Soil Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Thin and Ultrathin Structure of Envelopes of Stephanostomum baccatum (Trematoda: Acanthocolpidae) Metacercariae in Yellowfin Sole, Limanda aspera

The structure of the envelopes (capsule and cyst) surrounding metacercariae of Stephanostomum baccatum (Nicoll, 1907) in the second intermediate host, the yellowfin sole Limanda aspera (Pallas 1814), is examined with the methods of light and transmission electron microscopy. The cyst, presumably formed by secretions of the metacercarial tegument, consists of 2 layers: the outer, very thin layer of an electron-dense, finely granular substance and the inner layer composed of loose material of a moderate electron density that includes dense bodies varying in size, shape, and localization. The capsule, formed by the host's cells, is also organized into 2 distinct layers. The inner layer of the capsule is loose, consisting of evenly spaced debris of degenerated cells and lipid droplets with inclusions of intact macrophages between them. The outer layer of the capsule consists of parallel rows of cells arranged around the parasite, with fibroblasts and macrophages being dominant types and granulocytes and lymphocytes found in smaller numbers. Aggregations of collagen fibers are located in narrow spaces between the cells. The number of lipid droplets in the outer layer is significantly smaller than in the inner layer. The capsules formed around the examined trematodes have several structural features that distinguish them from those of S. baccatum and Stephanostomum sp. metacercariae recovered from other fishes of the family Pleuronectidae. The major morphological features of such capsules are the lack of epithelioid or giant multinucleated cells and the presence of numerous lipid droplets. Investigating the structural details of the envelopes surrounding metacercariae in trematodes, as well as other helminths, contributes to our scientific understanding of parasite biology, which can, in turn, have broader implications for understanding host-parasite interactions and evolutionary biology.

Topic: Parasite Biology and Host Interactions
Subfield: Ecology
Field: Environmental Science
Domain: Physical Sciences
Influence of Genes Associated with the Main Histocompatibility Complex on Deoxyribonucleic Acid Excision Repair Capacity and Bleomycin Sensitivity in Mouse Lymphocytes

In sets of mice congenic at H‐2 and upon two backgrounds, and selected according to known differences in strain‐specific lifespans, DNA repair efficiency in spleen cells was compared by two techniques: excision repair capacity following UV‐irradiation, and bleomycin sensitivity. Significant differences between certain congenic partner sets were noted with both techniques, suggesting that the main histocompatibility complex influences DNA repair capacity.

Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Confinement encoded in Landau gauge gluon and ghost propagators

An introduction is given into current lattice investigations of the non-perturbative gluon and ghost propagators, in the light of the Gribov-Zwanziger and Kugo-Ojima scenarios of confinement, in the context of results obtained from the non-perturbative Dyson-Schwinger approach in the continuum and in connection with the vortex mechanism of confinement.

Topic: Quantum Chromodynamics and Particle Interactions
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
Porous Carbon-Modified Silk-Derived Carbon Mesh for High-Performance Transparent All-Solid Supercapacitors

The practical application of transparent supercapacitors (TSCs) is limited by the inherent trade-off between transparency and conductivity, as well as the environmental and economic drawbacks of electrode materials. This study presents a novel and scalable method for fabricating porous carbon-modified silk-derived carbon fiber meshes as electrode materials for transparent supercapacitors. The process involves the in situ growth of a cobalt organic complex on a silk mesh, followed by carbonization to produce a flexible, transparent carbon fiber mesh with a hierarchical porous structure (specific surface area: 570 m2/g). The resulting material exhibits good mechanical properties and electrical conductivity due to the nanographene-like structure formed during the cobalt-catalyzed carbonization process. This TSC achieves an optical transparency of up to 65% and an aerial capacitance of 9.65 mF/cm2 at a scan rate of 0.01 V/s, surpassing many existing transparent electrodes. Additionally, the device demonstrates outstanding electrochemical stability, retaining 89% of its initial capacitance after 2000 cycles at a scan rate of 0.5 V/s, showcasing superior durability. This study presents a pioneering method for developing TSCs by utilizing sustainable silk-derived carbon materials and a cost-effective fabrication process.

Topic: Supercapacitor Materials and Fabrication
Subfield: Electronic, Optical and Magnetic Materials
Field: Materials Science
Domain: Physical Sciences
The Influence of Aromatic Side-Chains on the Aqueous Properties of pH-Sensitive Poly(L-lysine iso-phthalamide) Derivatives

The endosomal membrane has proven to be a challenging barrier for the delivery of therapeutic biomacromolecules, including DNA, siRNA and proteins, which are taken up by endosomes but cannot freely diffuse across lipid bilayers. Anionic polymers that undergo conformational changes and become membrane disruptive in low-pH environments have the potential to assist in the delivery of these biomacromolecules across the endosomal membrane to the cytosol. Such endosomolytic polymers have been synthesized through the grafting of hydrophobic side-chains to a poly(L-lysine iso-phthalamide) backbone. The phenylalanine grafted form of poly(L-lysine iso-phthalamide) has a pH-sensitive membrane disruptive profile corresponding to the pH range of maturing endosomes and, thus, has a favourable endosomolytic profile. In order to understand the influence of hydrophobicity versus pi-pi interactions mediated by aromatic rings, a tyrosine grafted form of poly(L-lysine iso-phthalamide) was synthesized and its aqueous pH-sensitive properties, cytotoxicity and endosomal disruptive capacity were compared to phenylalanine-grafted poly(L-lysine iso-phthalamide). The similarity between these two polymers' properties, despite the large difference in hydrophobicity between their side-chains, supports the conclusion that the aromatic character of sidechains in poly(L-lysine iso-phthalamide) is an important property, as opposed to hydrophobicity alone, in determining the effectiveness of acidic pH triggered endosomolysis.

Topic: RNA Interference and Gene Delivery
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
New ATP-competitive inhibitors of <i>E. coli</i> GyrB obtained from the mapping of the hydrophobic floor at the binding site: synthesis and biological evaluation

A diagram of the active site of E. coli gyrase B, highlighting the hydrophobic subsite, including key residues relevant to ligand binding.

Topic: Bioactive Compounds and Antitumor Agents
Subfield: Toxicology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
Effectiveness of Cervical Manual Mobilization Techniques versus Stretching Exercises for Pain Relief in the Management of Neck Pain: A Randomized Control Trail

Background: Although a huge literature is available regarding the efficacy of various physiotherapytechniques for neck pain. This study was to compare effectiveness of stretching exercises versus manualmobilization techniques in management of neck pain along withhome exercises program.Methodology: A randomized controlled trial parallel group design study was conducted on the patientssuffering from neck pain. Participants with the history of NP and aged between 19 to 60 years, Neckpain without radiculopathy, no history of trauma was included in the study. Two outcomes measureswere used. NPRS and neck pain disability questionnaire. Two groups were equally divided had twentyfivepatients each. Group A received treatment cervical stretching with strengthening exercises as hometreatmentprogram and group B received manual mobilization with strengthening exercises as hometreatmentprogram. Six sessions were given on alternate basis and assessed pre- and post-treatmentinformation of all patients.Result: The results of the study is that NPRS outcomes in two treatment groups, in stretching exercisesbefore treatment 68% samples found with moderate pain, whereas in manual mobilization techniques52% samples found with severe pain, after treatment, in stretching exercises 76% samples convertedto mild pain, and in manual mobilization techniques 88% samples converted to mild pain, howeverp-value of Mann Whitney U-test suggested that, both treatment performing similar on average in allpatients.Conclusion: The conclusion of the study is that both the treatment therapies are effective in Np andpatient condition is improving as such there were not any significant differences in these treatmentgroups. Patient’s quality of life is improving with the both therapies.

Topic: Musculoskeletal pain and rehabilitation
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Nonsurgical management of a patient with multiple dens invaginatus affecting all maxillary incisors

This paper discussed a patient with dens invaginatus (DI) in all maxillary incisors that was accompanied by supernumerary tooth and also bifid cingulum, lingual pit, and talon cusp on the other teeth. DI is a rare developmental malformation usually seen in the maxillary lateral incisors of permanent dentition. A healthy 22-year-old Iranian woman was referred for the treatment of carious teeth. Following comprehensive clinical and radiographic examination, that was diagnosed DI affecting all maxillary central and lateral incisors. Left maxillary central incisor was Type I and the other incisors were Type II, according to Oehlers classification. Furthermore, she had supernumerary tooth and Class III malocclusion. All teeth responded to sensibility tests, except right maxillary central incisor that was diagnosed pulp necrosis and asymptomatic apical periodontitis. Conventional root canal therapy was done for the right maxillary central incisor using mineral trioxide aggregate and gutta percha and AH26 sealer by thermoplastic method. After 18 months of follow-up, clinical and radiographical examination revealed periapical healing of the right maxillary central incisor and absence of pulp and periapical pathosis in other incisors. The early recognition of DI, correct diagnosis, and appropriate management of this tooth is essential to ensure favorable treatment outcome.

Topic: Oral and Maxillofacial Pathology
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Plant attributes interact with fungal pathogens and nitrogen addition to drive soil enzymatic activities and their temporal variation

Abstract Nitrogen enrichment can alter soil communities and their functioning directly, via changes in nutrient availability and stoichiometry, or indirectly, by changing plant communities or the abundance of consumers. However, most studies have only focused on one of these potential drivers and we know little about the relative importance of the different mechanisms (changes in nutrient availability, in plant diversity or functional composition or in consumer abundance) by which nitrogen enrichment affects soil functioning. In addition, soil functions could vary dramatically between seasons; however, they are typically measured only once during the peak growing season. We therefore know little about the drivers of intra‐annual stability in soil functioning. In this study, we measured activities of β‐glucosidase and acid phosphatase, two extracellular enzymes that indicate soil functioning. We did so in a large grassland experiment which tested the effects, and relative importance, of nitrogen enrichment, plant functional composition and diversity, and foliar pathogen presence (controlled by fungicide) on soil functioning. We measured the activity of the two enzymes across seasons and years to assess the stability and temporal dynamics of soil functioning. Overall β‐glucosidase activity was slightly increased by nitrogen enrichment over time but did not respond to the other experimental treatments. Conversely, plant functional diversity and interactions between plant attributes and fungicide application were important drivers of mean acid phosphatase activity. The temporal stability of both soil enzymes was differently affected by two facets of plant diversity: species richness increased temporal stability and functional diversity decreased it; however, these effects were dampened when nitrogen and fungicide were added. The fungicide effects on soil enzyme activities suggest that foliar pathogens can also affect below‐ground processes and the interacting effect of fungicide and plant diversity suggests that these plant enemies can modulate the relationship between plant diversity and ecosystem functioning. The contrasting effects of our treatments on the mean versus stability of soil enzyme activities clearly show the need to consider temporal dynamics in below‐ground processes, to better understand the responses of soil microbes to environmental changes such as nutrient enrichment. Read the free Plain Language Summary for this article on the Journal blog.

Topic: Soil Carbon and Nitrogen Dynamics
Subfield: Soil Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
HUBUNGAN MINUM OBAT ANTI HIPERTENSI DENGAN MELAKUKAN KONTROL TEKANAN DARAH RUTIN PADA LANSIA

Hypertension is a disease characterized by above-normal blood pressure , usually does not cause symptom, it is often called the silent killer. An estimated 76 % cases of hypertension in people who have not been diagnosed, in this case a person does not know that he was suffering from hypertension. This study aimed to get an overview of the factors that affect blood pressure control in the elderly. Methods: The study was a non - experimental (observational) with cross-sectional approach. The population in this study were all elderly people who come on Posyandu Lansia in Puskesmas Pulogadung district, East Jakarta with sample of 46 respondents. Results and Discussion: There was a significant relationship between taking antihypertensive medication ; have a history of hypertension ; and long suffered from hypertension with blood pressure control routine (p = 0.004 ; p = 0.018 ; p = 0.026). The factors that most influence on the elderly to perform routine blood pressure control is taking antihypertensive medication (p = 0.014 and Exp (B) = 45.5). A controlled blood pressure can reduce the risk factors of cardiovascular disease. To keep improving and maintaining the quality of the elderly can be done through activities in Posyandu Lansia with health education, monitoring the elderly who suffer from hypertension, and peer group

Topic: Public Health and Nutrition
Subfield: Pediatrics, Perinatology and Child Health
Field: Medicine
Domain: Health Sciences
Session 23 Overview: THz Circuits and Front-Ends

The THz frontier continues to be pushed by mainstream-CMOS circuits with excellent performance. The papers present diverse circuits and front-ends extending state of the art on linearity, signal generation/steering, and detection sensitivity. The first paper presents a THz upconverter leveraging the benefit of parametric gain using optimally biased varactors for enhanced even-order harmonic generation. A THz 2D beamsteering pixel-array source with the capability to spatially and electronically steer is presented in the second paper. The session continues with an ultra-low power and area THz detector with leading-edge noise performance and concludes with a W-band PLL demonstrating best-in-class jitter and FoM.

Topic: Radio Frequency Integrated Circuit Design
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
The Characteristics of Shoulder Muscles in Archery Athletes

BACKGROUND: This study evaluated the shoulder girdle muscle characteristics of elite archery athletes and provides suggestions for archery training programs.METHODS: This study enrolled 15 cases of high level archery athletes (7 males, 8 females) and 30 cases of (15 males, 15 females) sex, age-matched, healthy, non-athletic individuals. We measured peak torques of flexion (FL), extension (EX), abduction (ABD), adduction (ADD), external rotation (ER) and internal rotation (IR) of both shoulders at an angular velocity of 30°/sec, 60°/sec, and 180°/sec. The peak torques and peak torque ratios of FL/EX, ABD/ADD, and ER/IR of the two groups were compared.RESULTS: The archer group had a greater peak torque of IR and ADD, but only in the left shoulder (p &lt; 0.05). In the same group, both shoulders had greater peak torque of EX and lower peak torque of FL. The peak torque ratios of FL/EX of both shoulders were significantly lower in the archer group at all three angular velocities (p &lt; 0.05). The peak torque ratios of ABD/ADD were significantly greater in only the left shoulder of the archer group (p &lt; 0.05).CONCLUSIONS: The prominent characteristics of the shoulder girdle muscles of an elite archer are stronger adductor muscles of the bow shoulder and stronger extensors of both shoulders, as compared to healthy, non-athletic individuals. These muscle groups of the shoulder probably contribute a major role in maintaining the accuracy and stability during archery shooting. Hence, a training program that selectively enhances the adductor and extensor muscles could prove helpful in enhancing the archery skills of the athlete.

Topic: Mechanics and Biomechanics Studies
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Association of Mycobacterium Proteins with Lipid Droplets

Mycobacterium spp. are one of the few prokaryotes known to produce lipid droplets (LDs), and their production has been linked to aspects of persistent infection by M. tuberculosis . Unfortunately, little is known about LD production in these organisms, including how LDs are formed, their function, or the identity of proteins that associate with them. In this study, an established M. tuberculosis LD protein and a surrogate Mycobacterium host were used as model systems to study the interactions between proteins and LDs in bacteria. Through these studies, we identified a commonly occurring protein motif that is able to facilitate the association of proteins to LDs in prokaryotes.

Topic: Evolution and Genetic Dynamics
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Virtue and Criminal Negligence

This article addresses the contention of some prominent criminal law scholars – notably Jerome Hall and Glanville Williams – that negligence is an improper basis for the imposition of criminal punishment. An Aristotelian, virtue-ethics theory of punishment treats the inculcation of sound practical judgment as a function of punishment. The assessment of reasonable conduct implicit in negligence as a criterion of criminal fault fits comfortably within such a theory.

Topic: Free Will and Agency
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
CCDC 155200: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: X-ray Diffraction in Crystallography
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
ON THE REPROGRAMMING OF THE KREBS CYCLE IN HYPOXIC AND VHL-DEFICIENT CANCER CELLS

Tese de doutoramento em Bioquímica apresentada à Faculdade de Ciências e Tecnologia da Universidade de Coimbra

Topic: Radiation Therapy and Dosimetry
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences