jimnoneill/paper-to-field-training huggingface dataset:
CCDC 239509: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Deployment of Workforce in Global Health: What are the Priorities for China?

Abstract BackgroundChina has increasingly emerged as an important player in global health. However, compared to the developed countries, China still lacks the sufficient human resources for global health engagement with limited necessary qualified capacity. The priorities for the deployment of Chinese workforce in global health engagement remains unclear. This study aims to identify the priorities of the deployment of Chinese global health workforce by exploring the core competencies for Chinese global health workforce, factors influencing the deployment and the approach of deployment. MethodA total of 148 key stakeholders from 10 provinces in China conducting global health program during the recent 3 years were selected as the study sample. A structured questionnaire was developed to collect the data on four aspects, including the general information, core competencies, factors influencing deployment, and the deployment way. The questionnaire was distributed to the respondents through an online survey tool. All original data was exported to Microsoft Excel 2010 to calculate the frequency and percentage of every option. The descriptive analysis was made on the priorities of deployment of Chinese global health workforce. ResultsMore than half of respondents 51.4% (76/148) regarded “communication” as the most important competency of Chinese global health workforce while a large portion of Chinese Embassies 50.0% (6/12) and international organizations 75.0% (12/16) believed that “professional skills” was the paramount. In addition, 58.1% (86/148) of the participants agreed that incentive factors (salary, professional title, etc.) are the first factors influencing the deployment, whereas, a majority of 75% (12/16) international organization stakeholders emphasized “security” as the foremost factor. Furthermore, 60.8% (90/148) thought that staff should be deployed align with the needs of global health program implementation. ConclusionThe study shows the priorities of the deployment of Chinese global health workforce, including strengthening the competency of communication and professional skills, stressing the personal security and incentives, and catering to the program implementation.

Topic: Healthcare Systems and Reforms
Subfield: Finance
Field: Economics, Econometrics and Finance
Domain: Social Sciences
FCRL4 Is an Fc Receptor for Systemic IgA, but Not Mucosal Secretory IgA

Abstract Fc receptor–like (FCRL) 4 is an immunoregulatory receptor expressed on a subpopulation of human memory B cells of mucosa-associated lymphoid tissue. Fc receptor function of FCRL4 was demonstrated by binding of IgA to FCRL4 following heat aggregation of the Ig. In this study, we demonstrate that FCRL4 recognizes J chain–linked systemic IgA in the absence of heat aggregation. We further demonstrate that mucosal secretory IgA is not recognized by FCRL4 and that systemic IgA binding can be competitively inhibited by recombinant secretory component protein. Finally, we provide evidence that primary FCRL4-bearing human memory B cells are constitutively bound to IgA. Our study provides a mechanism for the negative regulatory activity of FCRL4 on AgR-mediated B cell activation.

Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Listening to Stanley Kubrick: The Music in His Films By Christine Lee Gengaro. Lanham, MD: Rowman &amp; Littlefield, 2014, pp. 305. $66.00 paper

"Listening to Stanley Kubrick: The Music in His Films By Christine Lee Gengaro. Lanham, MD: Rowman & Littlefield, 2014, pp. 305. $66.00 paper." Journal of Popular Film and Television, 44(2), pp. 121–122

Topic: Literature, Film, and Journalism Analysis
Subfield: Literature and Literary Theory
Field: Arts and Humanities
Domain: Social Sciences
Endurance training for judo athletes: Improving anaerobic and aerobic capacity in the high altitude

Background Problems: Judo is a sport that requires aerobic and anaerobic abilities. This is because the scoring in judo matches is different from other martial arts, where athletes will look for absolute 'ippon' points in one match. Therefore, training is needed that can support increasing aerobic and anaerobic capacity in judo athletes. Endurance training at high altitudes is a training method that is believed to have benefits for athletes' aerobic and aerobic capacity. Research Objectives: The study aims to examine the effect of endurance training on increasing the anaerobic and aerobic capacity of judo athletes based on the Special Judo Fitness Test (SJFT), which is a specific test for the sport of judo that can describe anaerobic and aerobic fitness according to the needs of judo. Methods: This research was conducted in the Puncak area of West Java, which is included in the highlands. An experimental method was used in this research on twenty-four Indonesian elite judo athletes who are carrying out training camps to face the SEA Games in Vietnam in 2021. The t test using SPSS Version 24 was used for data analysis in this study. Findings and Results: The results showed that there was a significant increase in anaerobic and aerobic capacity at high altitudes in judo athletes, as seen from the SJFT. Conclusion: This study concluded that endurance training could increase the anaerobic and aerobic capacity of judo athletes in the highlands. Endurance training at high altitudes for judo athletes is highly recommended because it has been proven to have a significant effect on increasing anaerobic and aerobic capacity. We recommend that judo coaches carry out training at high altitudes because it has been proven to improve the aerobic and anaerobic abilities of judo athletes.

Topic: High Altitude and Hypoxia
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Cloud Computing in Housing and Utility Services Monitoring Systems

The development of cloud technologies, miniaturization of computing and sensor devices has led to an explosive growth in the field of the Internet of Things. One of the promising research areas within the framework of this concept is smart homes, and, more broadly, smart cities, associated with increasing the values of such parameters of housing and utility services as energy efficiency, resistance to failures, failing and efficiency in general. This article is devoted to the development of an information system for monitoring, remote management and maintenance of engineering systems at the housing infrastructure facilities. The functions of information system include the operational status control of engineering systems on housing infrastructure objects, support, maintenance, repair, prediction and alerts on routine, unplanned and critical situations. Data from engineering objects is transferred over a network to the cloud for processing and subsequent analysis. The IoT infrastructure is used for collecting data from engineering objects. The article presents the results of a comparative analysis of technologies and protocols, and substantiates the proposed architectural solution based on the Raspberry and MQTT.

Topic: IoT and Edge/Fog Computing
Subfield: Computer Networks and Communications
Field: Computer Science
Domain: Physical Sciences
Inhibition of platelet aggregation and thromboxane production by low concentrations of aspirin <i>in vitro</i>

1. The aspirin concentrations previously reported to inhibit platelet aggregation in vitro (40–500 μmol/l) are much greater than those required in vivo in man (5 μmol/l). 2. Human platelet-rich plasma was incubated with buffer or various aspirin concentrations at 37°C for up to 4.5 h. Platelet aggregation and thromboxane generation were measured in response to collagen (0.4–6.3 μg/ml) and adenosine 5′-pyrophosphate (0.5–4 μmol/l). 3. The concentration of aspirin needed to inhibit platelet aggregation in response to a critical concentration of aggregating agent (lowest concentration to cause greater than 50% aggregation) was lower than that required for higher concentrations of aggregating agent. 4. With more prolonged incubation times with aspirin, lower concentrations of aspirin inhibited platelet aggregation. 5. Inhibition of platelet aggregation and thromboxane formation by 10 μmol/l aspirin was maximal by 90 min. There was progressive inhibition by 3 μmol/l aspirin during incubation for 270 min. By the end of this time there was also significant inhibition by 1 μmol/l aspirin. 6. The apparent discrepancy between inhibitory aspirin concentrations in vivo and those observed in vitro in previous studies appears to have been resolved by extending the incubation time of platelets with low aspirin concentrations, thus mimicking the conditions in vivo.

Topic: Antiplatelet Therapy and Cardiovascular Diseases
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Validation of Real-Time RT-PCR for Detection of SARS-CoV-2 in the Early Stages of the COVID-19 Outbreak Without Emergency Use Authorization Reagents in the Republic of Korea

Abstract Background: A real-time reverse transcription polymerase chain reaction (RT-PCR) assay for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was developed to rapidly diagnose coronavirus disease 2019 (COVID-19). Early diagnosis of COVID-19 enables timely treatment and the implementation of public health measures. We validated the sensitivity, specificity, precision, linearity, accuracy, and robustness of a real-time RT-PCR-based assay for SARS-CoV-2 detection and compared the sensitivity and specificity of Emergency Use Authorization (EUA)-approved reagents for COVID-19 with those of the real-time RT-PCR method. Methods: The real-time RT-PCR-based assay was performed to specifically amplify genomic markers of SARS-CoV-2. Results: The real-time RT-PCR assay was highly specific for SARS-CoV-2, and did not amplify genomic fragments of 13 other viruses that cause respiratory diseases. The assay showed high linearity when conducted with a viral isolate from a patient with COVID-19 together with plasmids containing the target genes. The assay showed good repeatability and reproducibility, with a coefficient of variation of 3%, and detected SARS-CoV-2 with a limit of detection of 1 PFU/mL. Conclusions: The present real-time RT-PCR-based assay can diagnose COVID-19 with high accuracy and sensitivity. This approach is highly effective and can facilitate the early diagnosis of COVID-19 without the use of EUA reagents in the Republic of Korea.

Topic: SARS-CoV-2 detection and testing
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Conditions Affecting the Release of Heavy and Rare Earth Metals from the Mine Tailings Kola Subarctic

In the Kola Subarctic, a mining industry has developed, which is a source of environmental pollution with heavy metals. The objects of study were the tailings of three large mining enterprises in the region: apatite-nepheline, complex and loparite ores. The geotechnical characteristics were studied, and the granulometric composition of the samples was established. The main minerals that make up the material of ore dressing tailings have been determined. Using inductively coupled plasma mass spectrometry, the content of trace elements, in particular heavy metals and rare earth elements, has been established. The enrichment factor, the geoaccumulation indexes, the potential ecological risk index factor and the potential environmental hazard index have been calculated. Priority pollutants characteristics for specific objects have been identified. It is noted that the finely dispersed material of the tailings of loparite and complex ores is 1.5–3 times enriched in heavy and rare earth metals in comparison with the total material of the tailings. In laboratory conditions, experiments were carried out to simulate the process of interaction of dust particles with soil solutions containing different amounts of dissolved organic matter and at average seasonal temperatures. It was found that a decrease in the pH of the solution and an increase in the amount of organic carbon and temperature lead to the mobilization of heavy and rare earth metals from the tailings.

Topic: Geochemistry and Geologic Mapping
Subfield: Artificial Intelligence
Field: Computer Science
Domain: Physical Sciences
Obese Patients After Laparoscopic Adjustable Gastric Banding Complications and The Influence on Body Mass Index and Comorbidities.

LAGB is a safe and effective approach in short-term management of morbid obesity. Weight loss, complications and resolution of comorbidities are comparable with the other obesity procedures.

Topic: Bariatric Surgery and Outcomes
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Why 2016 House races still matter, Sanders in voter data spat with DNC, and Congress’ budget deal: US national blog roundup for 12 – 18 December

USAPP Managing Editor, Chris Gilson looks at the best in political blogging from around the Beltway. Our roundup of state political blogging will follow over the weekend.

Topic: Electoral Systems and Political Participation
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
EEG Signal Classification for Mental Stress During Arithmetic Task Using Wavelet Transformation and Statistical Features

This paper on electroencephalogram (EEG) analysis describes a feature extraction model based on discrete wavelet transforms for the classification of EEG signals during a mental arithmetic task as mental stress. Stress is a normal part of life. Stress analysis is more important than sleep analysis because stress causes sleeping disorders. The EEG is used to monitor the electrical activities of the brain. The features were computed in time-frequency domain using wavelet decomposition and they were extracted from single-channel EEG signal during and before a mental arithmetic task. The amplitude, power, and frequency of extracted decomposed signals changed significantly during mental stress compared to the state before the mental arithmetic task. 12 state-of-art statistical features were computed from each decomposed signal (5 decomposed frequency bands gave a total of 60 features) of a fixed window of 10 seconds. The Neighborhood Component Analysis (NCA) feature selection method was used to find the most significant features, which resulted in the discovery of four features. Finally, mental stress was classified using the selected four features and Ensemble Subspace KNN classifier. The classifier's performance was evaluated on 11 subjects using a five-fold cross-validation technique, which crossed state-of-the-art methodologies in the literature by 77.3 percent.

Topic: EEG and Brain-Computer Interfaces
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Postharvest Handling Practices and Perception of Potato Safety among Potato Traders in Nairobi, Kenya

Postharvest handling of the potato is an important factor not only in preventing postharvest losses but also in maintaining its safety and nutritional quality. Exposure of the potato to unfavorable conditions such as light, extreme temperatures, and bruising can result in accumulation of glycoalkaloids, which are toxic substances. This study was a cross-sectional survey which aimed to investigate the postharvest handling practices of potatoes and perception of potato safety among open air market traders in Nairobi County, Kenya. Information was collected from 100 potato traders using a semistructured questionnaire that assessed postharvest handling practices such as potato transportation, exposure to sunlight, and storage. Results indicated that most of the potatoes (88%) took one day to be transported to the market, with the storage period at the market ranging from 2 to 3 days for most traders (42%). Forty-seven percent (47%) of the vehicles and hand-pulled carts used to transport potatoes had open backs, while 53% had closed backs. Over half (69%) of the potatoes in the markets were directly exposed to sunlight, with 75% of the traders leaving their potatoes in the open covered with a polythene bag after the day's activities. Greening, sprouting, or bruised potatoes were mostly sold as seed, sold to restaurants and French fries vendors, or sold to consumers at a lower price. More than half of the traders did not think that consumption of greened potatoes is harmful to health. The results clearly show that there is poor handling of the potatoes by the traders which increases the risk of consumer exposure to glycoalkaloids. There is, therefore, a need to create awareness among traders on appropriate postharvest handling of potatoes to protect consumer health and reduce economic losses as well.

Topic: Potato Plant Research
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Stellarangia namibensis (Teloschistaceae) out of the Namib Desert

During lichenological fieldwork along the coast of the Atlantic Sahara, Morocco, we collected some remarkably long lobed “Caloplaca” specimens, which turned out to be Stellarangia namibensis. This is the first record of this species in the northern hemisphere, and represents a significant extension of the known range of a lichen previously thought to be endemic to the Namib Desert.

Topic: Lichen and fungal ecology
Subfield: Ecology, Evolution, Behavior and Systematics
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Answer to case of the month #121. Diagnostic imaging of small bowel obstruction secondary to intussusception in an adult female.

A 51-year-old woman presented with confusion and headache of increasing intensity. She had a history of renal cell carcinoma of the right kidney with metastasis to her left lung. During her time in hospital, the patient had nausea and one episode of vomiting. A soft abdomen with tinkling bowel sounds, mild left lower-quadrant tenderness, and equivocal rebound tenderness were notable on preoperative abdominal examination. There was no mass, blood, or stored fecal material in the rectum.

Topic: Gastrointestinal disorders and treatments
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
The effect of veterinarian’s communication skills on the client’s ability to recall information

Introduction: Conveying information is an important objective of a veterinary consult. In order to effectively improve the transfer of information, it is important to know which communication factors influence it. This study will explore whether there are significant relations between the communication skills of a veterinarian and the degree of clients to recall veterinary information.&#13;\n&#13;\nMaterials and methods: For this study 30 clients were asked to fill out a feedback form based on their first consult at the division of medical oncology and radiotherapy at the University clinic of companion animals. With this feedback form the clients rate the communication skills of the veterinarian (such as use of language, taking enough time, encouraging clients to ask questions and checking whether the client has understood the information). Four hours after the consult, the clients were called to assess how much information from the consult was recalled, by scoring the amount of keywords the clients were able to reproduce. The presence of significant correlations between how respondents rated the veterinarian’s communication skills and the extent of veterinary information they recalled was analyzed.&#13;\n&#13;\nResults/conclusions: This study shows that the ability of clients to recall information is significantly lower in the consultations when clients feel less encouraged to ask questions during the consult. Furthermore, there is evidence in this study that aging has an negative impact (≈ -0,266% of the total number of keywords per year) for clients on the ability to recall veterinary information.

Topic: Veterinary Practice and Education Studies
Subfield: Speech and Hearing
Field: Health Professions
Domain: Health Sciences
159930_1_supp_0_d72rhn.doc from Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma

159930_1_supp_0_d72rhn.doc from Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma

Topic: Melanoma and MAPK Pathways
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Gap States at Low-Angle Grain Boundaries in Monolayer Tungsten Diselenide

Two-dimensional (2D) transition metal dichalcogenides (TMDs) have revealed many novel properties of interest to future device applications. In particular, the presence of grain boundaries (GBs) can significantly influence the material properties of 2D TMDs. However, direct characterization of the electronic properties of the GB defects at the atomic scale remains extremely challenging. In this study, we employ scanning tunneling microscopy and spectroscopy to investigate the atomic and electronic structure of low-angle GBs of monolayer tungsten diselenide (WSe2) with misorientation angles of 3-6°. Butterfly features are observed along the GBs, with the periodicity depending on the misorientation angle. Density functional theory calculations show that these butterfly features correspond to gap states that arise in tetragonal dislocation cores and extend to distorted six-membered rings around the dislocation core. Understanding the nature of GB defects and their influence on transport and other device properties highlights the importance of defect engineering in future 2D device fabrication.

Topic: 2D Materials and Applications
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Improvement method of WSNs for real-time monitoring

A WSNs-based real-time monitoring system was built in view of the application in hazardous materials transportation monitoring.MAC layer protocol and physical layer transmission time sequence of the monitoring system were improved and optimized.Priority supported GDCF algorithm was introduced after improving the original BEB algorithm of MAC layer.Effectiveness analysis was made for the RTS/CTS mechanism of MAC layer.Sleep mode was introduced for energy saving.Time sequence was optimized to reduce data transmission time and collision probability in physical layer data transmission.Practical test was made by IRIS node platform installing on an engineering automobile.Test result shows that the drop rate using improved backoff algorithm has no significant change with the increase of network node number.The drop rate without RTS/CTS mechanism reduces from the original about 20% to less than 6% when the giving sampling interval time is 50 ms,and 95% energy is saved in every working period.Design goal is achieved in improved time sequence of wireless data transmission,and the performance requirements in real-time monitoring system of WSNs are satisfied in practical application.3 tabs,4 figs,16 refs.

Topic: Advanced Sensor and Control Systems
Subfield: Control and Systems Engineering
Field: Engineering
Domain: Physical Sciences