jimnoneill/paper-to-field-training huggingface dataset:
Conformational changes in the progesterone binding globulin-progesterone complex

An improved purification procedure for the progesterone-binding globulin (PBG) of the pregnant guinea pig has been developed utilizing sulfopropyl Sephadex, a strong cation exchanger, in the first step. The method exploits the low pI (2.8) and favorable acid stability of the glycoprotein. Subsequent chromatographies on DEAE-cellulose and Sephadex G-200 afford a highly purified PBG that exhibits the previously observed polydispersity (R.M. Burton et al. (1974), Biochemistry 13, 3554-3561). Circular dichroism, optical rotatory dispersion, and difference uv spectra all indicate the purified protein to undergo a conformational transition upon forming a complex with a steroid ligand. The CD and ORD spectra cannot be interpreted in terms of tertiary structure probably due to carbohydrate contributions. However, the difference spectra indicate strong perturbation of both a tryptophan residue and the steroid chromophore in the complex.

Topic: Protein Interaction Studies and Fluorescence Analysis
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
BUILDING BOOKS FROM BOOKS THE NEXT PAGE IN PUBLISHING

This report documents the launch of a new Web application (BookRiff) as a case study of one opportunity for the book publishing industry to increase revenues by diversifying digital publishing platforms. Because this application is a venture of D&amp;amp;M Publishers Inc, it has a unique position among other digital initiatives that largely originate outside of the industry. As such, this study demonstrates both the needs of the publishing industry to expand digital revenue streams, and the capabilities and limitations of Internet applications to respond to those needs. Part one describes publishers’ current goals relating to digitization. Part two describes BookRiff as a viable incentive to overcome current problems, as well as a revolutionary idea in the digital publishing area. Part three documents building the site to demonstrate how publishers’ concerns are dealt with as the application takes shape, and how they will come into play as it continues to evolve.

Topic: Publishing and Scholarly Communication
Subfield: History and Philosophy of Science
Field: Arts and Humanities
Domain: Social Sciences
Ring enlargement of diaziridinone with 2-substituted pyrrole leading to bicyclic triazine and its transformation to novel mesomeric betaine

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRing enlargement of diaziridinone with 2-substituted pyrrole leading to bicyclic triazine and its transformation to novel mesomeric betaineMitsuo Komatsu, Mitsuharu Kobayashi, Shinobu Itoh, and Yoshiki OhshiroCite this: J. Org. Chem. 1993, 58, 24, 6620–6624Publication Date (Print):November 1, 1993Publication History Published online1 May 2002Published inissue 1 November 1993https://pubs.acs.org/doi/10.1021/jo00076a020https://doi.org/10.1021/jo00076a020research-articleACS PublicationsRequest reuse permissionsArticle Views203Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Topic: Synthesis and Characterization of Heterocyclic Compounds
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Reactions of oxygen atoms with acetylene

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of oxygen atoms with acetyleneDavid G. Williamson and Kyle D. BayesCite this: J. Phys. Chem. 1969, 73, 5, 1232–1237Publication Date (Print):May 1, 1969Publication History Published online1 May 2002Published inissue 1 May 1969https://pubs.acs.org/doi/10.1021/j100725a009https://doi.org/10.1021/j100725a009research-articleACS PublicationsRequest reuse permissionsArticle Views124Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts

Topic: Fluorine in Organic Chemistry
Subfield: Pharmaceutical Science
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
Environmental Influences on the Distribution of Mangroves on Bahamas Island

Mangrove forests provide valuable ecosystem services but are declining in many tropical locations. The abundance of mangrove species in coastal fringe forests is related to biotic processes such as species succession or competition and abiotic factors, including nutrient availability, physiochemical water quality, soil composition, and tidal inundation. We examined the abundance of Rhizophora mangle and Avicennia germinans relative to environmental factors, including porewater chemistry, soil substrate, and distance from the ocean, on Bahamas Island. In this system, R. mangle were primarily found in litter-dominated soils and abundances were positively related to distance from the ocean, while A. germinans was only found in sandy soils closest to the ocean. Although phosphate, alkalinity, and salinity in porewater did not explain the distribution of species, free chloride varied significantly with distance from the ocean. These results suggest that soil conditions and tidal inundation may help determine the distribution of mangrove species on Caribbean islands. DOI: http://dx.doi.org/10.3126/jowe.v6i0.6081 J Wet Eco 2012 (6): 16-24

Topic: Coastal wetland ecosystem dynamics
Subfield: Ecology
Field: Environmental Science
Domain: Physical Sciences
Raising the National Revolutionary Army

In 1937, the Nationalists under Chiang Kaishek were leading the Chinese war effort against Japan and were lauded in the West for their efforts to transform China into an independent and modern nation; yet this image was quickly tarnished. The Nationalists were soon denounced as militarily incompetent, corrupt, and antidemocratic and Chiang Kaishek, the same. In this book, van de Ven investigates the myths and truths of Nationalist resistance including issues such as: the role of the US in East Asia during the Second World War the achievements of Chiang Kaishek as Nationalist leader the respective contributions of the Nationalists and the Communists to the defeat of Japan the consequences of the Europe First strategy for Asia. War and Nationalism in China offers a major new interpretation of the Chinese Nationalists, placing their war of resistance against Japan in the context of their prolonged efforts to establish control over their own country and providing a critical reassessment of Allied Warfare in the region. This groundbreaking volume will interest students and researchers of Chinese History and Warfare.

Topic: Vietnamese History and Culture Studies
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Pengaruh Disiplin Kerja dan Pemberian Insentif terhadap Kinerja Karyawan PT Putra Karisma Palembang

This study aims to analyze the effects of work discipline and incentives on the performance of employees of PT Putra Karisma Palembang. The sample was selected using the saturated sample technique. Data from 57 respondents were collected through interviews, documentation, and questionnaires. This study implemented the multiple linear regression method to analyze data. The results prove that partially each of work discipline and incentives has no significant effect on employee performance. However, simultaneously work discipline and incentives have a significant effect on employee performance. This insight is beneficial for PT Putra Karisma Palembang. To improve employees' performance, the company should consider both work discipline and incentives factors together. Penelitian ini bertujuan untuk menganalisis pengaruh disiplin kerja dan pemberian insentif terhadap kinerja karyawan PT Putra Karisma Palembang. Sampel dipilih menggunakan teknik sampel jenuh. Data 57 responden dikumpulkan melalui wawancara, dokumentasi, dan kuesioner. Studi ini mengimplementasikan metode regresi linier berganda untuk menganalisis data. Hasil investigasi membuktikan bahwa secara parsial baik disiplin kerja maupun pemberian insentif masing-masing tidak berpengaruh signifikan terhadap kinerja karyawan. Tetapi, secara simultan disiplin kerja dan pemberian insentif berpengaruh signifikan terhadap kinerja karyawan. Fakta ini bermanfaat bagi PT Putra Karisma Palembang. Untuk meningkatkan kinerja karyawan, maka perusahaan harus mempertimbangkan faktor disiplin kerja dan pemberian insentif secara bersama-sama.

Topic: Employee Performance and Management
Subfield: Human Factors and Ergonomics
Field: Social Sciences
Domain: Social Sciences
A qualitative study exploring the application of psychosocial screening to identify psychological conditions in non-surgical aesthetic patients

This study explores medical aesthetic practitioners' initial and ongoing application of psychosocial screening, to identify existing or emerging psychological disorders or conditions in non-surgical aesthetic patients. The increased demand for non-surgical aesthetic treatments correlates with the rise of patients who present with existing or evolving psychosocial problems or issues. Therefore, patients must be appropriately and adequately assessed, to identify those vulnerable individuals who are not suitable for treatment or whose treatments may exacerbate underlying psychological conditions. Identification can support signposting to trained professionals to ensure appropriate holistic care. Moreover, the study explores which validated screening tools have been adopted into practice, and routes for guiding patients should concerns arise.

Topic: Body Image and Dysmorphia Studies
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Austen's fans and fans' Austen

Abstract A corpus of Jane Austen's fanfic is constructed from sequels published in print and on line; it is then compared with a corpus of Austen's own writing, as well as one of contemporary romance fiction. Through analysis of the corpora, the “vertical intertextuality” of Austen's text and the fanfic corpus, and the “horizontal intertextuality” of contemporary romance fiction corpora and the fanfic corpus are articulated. The results illustrate that, although claiming to emulate her writing faithfully, Austen's fans reconstruct a modern Austen who is writing contemporary romance fiction through the “old” characters such as Elizabeth and Darcy. The different “Austens” emerging from this corpus research and other scholars' reading of Austen suggest that the death of the “Author” is only part of the story: we see not only the Author's death and the birth of the Reader, but a ghostly projection of a new “Author” in the reader's cultural context.

Topic: Authorship Attribution and Profiling
Subfield: Artificial Intelligence
Field: Computer Science
Domain: Physical Sciences
Local and National Democracy in Political Reconstruction

Abstract After conflict or breakdown of the state, successful democratic development will require an ample supply of leaders who have good reputations for responsible public service that can benefit all citizens. This essential supply of trusted democratic leadership can develop in responsible institutions of democratic local government, where successful local leaders can prove their qualifications to compete for higher office. If a transition to democracy begins with only national elections, however, then the winners will acquire a natural interest in centralizing power around themselves, and so political decentralization thereafter may become more difficult. Thus, those who would support the development of a new democracy need to recognize the potential advantages of decentralizing some power to elected local governments.

Topic: Political Conflict and Governance
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
ANMC depot, Dar es Salaam, Tanzania, 1918

“ANMC ground.” Landscape view of long thatched huts in front of large palm trees. The African Native Medical Corps (ANMC) arrived in Dar es Salaam in July 1917 and the, mainly Ugandan, orderlies worked with the Royal Army Medical Corps (RAMC) during the East African Campaign. ❧ The image is from an album chronicling the war time experiences of Archibald Clive Irvine (1893-1974) in German East Africa and Portuguese East Africa with the Royal Army Medical Corps. During this time he would meet Dr John W Arthur which in turn would lead to his missionary work at Chogoria in Kenya.

Topic: Actinomycetales infections and treatment
Subfield: Microbiology
Field: Medicine
Domain: Health Sciences
Factors affecting outcomes of liver transplantation: an analysis of OPTN/UNOS database.

This was a historic cohort analysis based on 110,521 patients who underwent liver transplant between 1987 and July 2011 in the United States and were reported to the UNOS registry. In addition to univariate Kaplan-Meier survival analyses, we used cox proportional hazard analysis and multiple logistic regression analysis to evaluate hazard ratios adjusted for clinical factors. The overall 5- and 10-year patient survival rates were 81% and 72%, respectively, for 4,412 recipients of living donor livers and 73% and 59%, respectively, for 106,109 recipients of deceased donor livers. Multivariate analyses suggest that these differences are due to demographics, including patient age rather than differences due to the donor organs. Recipients of zero HLA-mismatched livers had significantly worst graft survival (HR 1.29, p = 0.02) compared with those given an HLA mismatched graft. This appears to be due in part to graft versus host disease. Among recipients who experienced GVHD, multivariate analysis revealed that zero mismatch of HLA-A (HR 2.75), zero mismatch of HLA-B (HR 4.79), recipient age > 65 (HR 2.57) and Asian recipient (HR 2.70) were significant risk factors for GVHD respectively.

Topic: Organ Transplantation Techniques and Outcomes
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Maternal Care in Relation to Infant Behavior in the Squirrel Monkey

Observation of a mother squirrel monkey with her dead infant and an experiment with another mother and her viable 10-day-old infant are used to support the following points. (1) The typical, passive maternal care given by the squirrel monkey mother to her young is in part influenced by the behavior of the infant. (2) In response to certain behaviors of the infant, the squirrel monkey mother can exhibit behaviors that for her are otherwise improbable, including bipedal carrying and cradling of the infant. Implications of these findings for inferring the origin of bipedalism in primates are considered.

Topic: Primate Behavior and Ecology
Subfield: Social Psychology
Field: Psychology
Domain: Social Sciences
Introduction to men's mental health

Abstract Psychiatry has advanced enormously in the last 100 years, but so has its complexity, which can prove daunting to primary care physicians and even to psychiatrists. Longitudinal studies have frequently adopted narrow, simplistic, or reductionistic and impressionistic approaches that serve to harm rather then help men. Modern physicians and providers need to be sophisticated, scientific, and broad based in their approaches. The practitioner who wants to understand the intricate problems of men's mental health must be dedicated to gaining knowledge and accumulating clinical experience and wisdom over a lengthy time. Men must be given the time, study and respect they need to function in an ever more complicated world and environment. There is much to be done and many rivers to cross: psychoses in men, mood disorders, attention deficit hyperactivity disorder and its terrible sequellae if left untreated, anxiety disorders that affect the performance and happiness of men, the role of childhood trauma and neglect on the subsequent resiliency and mental health, how men are mistreated in the criminal justice systems, a host of antagonisms and prejudice towards men which deeply affects their self esteem, chronic substance abuse and the issues of self-medication for psychic anguish and the relation to violent behaviors, the workplace and its stresses and inconsistencies, unemployment and its effects on men, the effect of divorce on men and their subsequent enforced isolation from their children, and many others.

Topic: Gender Roles and Identity Studies
Subfield: Gender Studies
Field: Social Sciences
Domain: Social Sciences
MTA Enhances the Potential of Adipose-Derived Mesenchymal Stem Cells for Dentin–Pulp Complex Regeneration

The aim of the current study was to investigate the effects of mineral trioxide aggregate (MTA) on the proliferation and differentiation of human adipose-derived mesenchymal stem cells (Ad-MSCs) as a surrogate cell source in futuristic stem-cell-based endodontic therapies. Human Ad-MSCs and mesenchymal stem cells derived from bone marrow (BM-MSCs) were isolated from liposuction waste adipose tissue and femur, respectively, and the effects of MTA-conditioned media on their viability, mineralization potential, and osteo/odontogenic differentiation capacity were subsequently evaluated. Alkaline phosphatase (ALP) activity, quantitative alizarin red S staining, and quantitative reverse transcription-polymerase chain reaction (qRT-PCR) analyses were performed to investigate and compare the osteo/odontogenic induction potential of MTA on the Ad/BM-MSCs. The results of cytotoxicity assay revealed that at different concentrations, MTA-conditioned medium was not only biocompatible toward both cell types, but also capable of promoting cell proliferation. ALP activity assay showed that 0.2 mg/mL was the optimal concentration of MTA-conditioned medium for osteo/odontogenic induction in Ad/BM-MSCs. The expression of osteo/odontogenic gene markers was increased in Ad/BM-MSCs treated with 0.2 mg/mL MTA-conditioned media. Our results indicated that MTA can efficiently enhance the osteo/odontogenic potential of Ad-MSCs, and thus they can be considered as a better cell source for dentin–pulp complex regeneration. However, further investigations are required to test these potentials in animal models.

Topic: Endodontics and Root Canal Treatments
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Growth Responses of Two Cultivated Okra Species (&lt;i&gt;Abelmoschus caillei&lt;/i&gt; (A. Chev) Stevels and &lt;i&gt;Abelmoschus esculentus&lt;/i&gt; (Linn.) Moench) in Crude Oil Contaminated Soil

The morphological distinctiveness of two cultivated Okra species- Abelmoschus caillei and Abelmoschus esculentus was investigated using six accessions; three for each species in crude oil contaminated soil. The seeds were collected from home gardens in Benin City and NIHORT. Morpho-agronomic characters such as numbers of days from sowing to germination, plant height, stem base diameter, stem color and pubescence, leaf shape and color, number of leaves produced, growth habit, branching, fruit and fruiting characters were determined. The growth response of the different accessions varied significantly (p&lt; 0.05). Soil chemical analysis revealed decreased levels of pH, Phosphorus and Potassium in the contaminated soil. Generally, all the quantitative characters including number of flower buds and flowers produced, fruit length, height of plant and stem girth were reduced in plants (Okra) grown in the contaminated soil while most of the qualitative characters such as pigmentation and shape of plant organs were less affected. Thus, it can be suggested from the study that crude oil contamination of soil may lead to reduction in growth characteristics.Keywords: Crude oil, Soil, Morpho-agronomic characters, Abelmoschus caillei, A. esculentus.

Topic: Agricultural Practices and Plant Genetics
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Extinction and infrared emission from fractal dust grains

In current models of interstellar dust, such as that of Mathis, Rumpl and Nordsieck (1977) or Draine and Lee (1984), several assumptions are made about the dust. First, the size or sizes must be assumed. Careful interpretation of the interstellar extinction curve reveals that the far-UV rise is most likely caused by small particles (∼ hundredth of a micron), whereas the visible extinction requires a much larger particle size (∼ 0.1 μm). Authors have assumed either power law or exponential size distributions. A second assumption is that of the dust composition which may be deduced from the observed spectral features. The usual interpretation of these features are the presence of silicates, carbonaceous compounds, and in some cases, icy mantles. A third assumption concerns the shape of the dust. Past models have assumed spherical, spheroidal, and cylindrical grains. Polarization of starlight in the infrared around various sources implies that dust grains must be non-spherical and aligned. The grain formation process of nucleation and growth, thought to be a stochastic one, most certainly would not produce spheres or perfect cylinders. The subsequent processing of grains would also lead to irregularly shaped particles. Since the shape plays an important role in determining the extinction and infrared properties of interstellar dust, we attempt to examine the effect of irregularly shaped dust grains on models of interstellar extinction curves.

Topic: Advanced Mathematical Theories and Applications
Subfield: Statistical and Nonlinear Physics
Field: Physics and Astronomy
Domain: Physical Sciences