jimnoneill/paper-to-field-training huggingface dataset:
Design and Research on the Application of Flipped Classroom in Business English Teaching in Higher Vocational Education

In order to provide real Business English learning context, to greatly improve teaching and learning efficiency, to cultivate student’s autonomous learning ability, research on flipped classroom teaching is made in this paper. Background theories for flipped classroom are briefly discussed. A new flipped classroom teaching model is designed and constructed. Business English Curriculum under the new model is further designed and presented. And the new teaching model is also applied in Business English teaching. To assess the application effect of the new flipped classroom teaching model, a survey is conducted and presented at the end of the probationary period. Questionnaire and interview are applied. The results show that the newly-developed model has many advantages over traditional teaching. The new model reconstructs Business English learning process into three phases; it breaks through the limitations of time and space and allows for individualized learning; the follow-up assessment system provides instantaneous feedback and ensures personalized teaching and learning. Drawbacks and challenges of the new model are also pointed out. E-learning resource is not rich enough to meet the demands of students at different levels. The assessment function is to be improved to reflect students’ learning more exactly and objectively.

Topic: Innovative Teaching Methods
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Effect of Moringa Leaf Extract on Growth and Yield of Tomato

This study delves into the effects of Moringa oleifera leaf extract (0%, 3%, 6%, and 9% V/V) on tomato plant growth. Employing a randomized design, the 6% concentration emerges as a key player, significantly boosting performance. Results include heightened leaf count, increased height, larger and heavier fruits, improved firmness, volume, and elevated chlorophyll content. Intriguingly, the 9% concentration indicates a potential for increased branches, suggesting enhanced fruit production. Fruit pH remains consistently unaffected across treatments. Integrating moringa leaf extract, particularly at 6% and 9%, not only enhances tomato plant productivity and fruit quality but also lays the ground work for sustainable cultivation practices. This research contributes valuable insights for optimizing growth conditions, there by offering a pathway to improving overall crop yield and agricultural sustainability.

Topic: Moringa oleifera research and applications
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
The evolving educational needs of nurses caring for the older adult: a literature review

In this paper reporting the findings of a study commissioned by the National Board for Nursing, Midwifery and Health Visiting for Scotland, the intention was to try to identify key sources in the literature concerning the educational needs of staff moving from hospital-based to community-based services for older people. The keywords ‘community nurse education’, ‘elderly nursing’ and ‘community elderly nursing’ were used to search the databases CINAHL, MEDLINE and EMBASE between 1993 and 1997. The results were rather sparse, but the literature that was located emphasised the importance of a multidisciplinary approach to care, supported by shared learning for the professionals involved. 62 references.

Topic: Aging and Gerontology Research
Subfield: Neuropsychology and Physiological Psychology
Field: Psychology
Domain: Social Sciences
Evaluation of Interface Strength between Submicron-structure and Substrate Based on Fracture Mechanics Concept

Analytical and experimental studies are carried out to evaluate interface strength between submicron structures and substrates on the basis of the fracture mechanics concept. Finite element analyses reveal that the stress intensity near the interface edge between a dot and substrate greatly increases with an increase of the aspect ratio of the dot. Delamination tests for submicron chromium (Cr) dots with different aspect ratios on a silicon dioxide (SiO_2) substrate are conducted by means of a modified AFM. The results show that the smaller load is required to separate the dots with higher aspect ratio from the substrate. This is desirable to evaluate the interface fracture toughness.

Topic: Advanced Surface Polishing Techniques
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Restorative and Periodontal Challenges in Adults with Dystrophic Epidermolysis Bullosa

Oral manifestations of dystrophic epidermolysis bullosa (DEB) include blistering of the oral mucosa, scarring, limited mouth opening, decreased mobility of the tongue, restrictions in oral functions and a high incidence of caries. Adult oral health management is challenging and requires unique strategies, which have not been well described in the published literature. We present a case of DEB focusing on the obstacles encountered during restorative and periodontal care and recommendations for appropriate treatment.

Topic: Skin and Cellular Biology Research
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Mechanical characterization of solder interconnections on functionalized, copper-containing polymer thick-film pastes for hybrid integration

Abstract In this work, on different substrate materials thermally cured polymer thick-film (PTF) pastes are connected to surface mount technology resistors using a SnBiAg solder alloy. The effect of substrate pre-treatment with atmospheric plasma and thermal cycling on the shear strength of these interconnections is investigated, and the shear forces obtained are graded using United States Defense Standard / Military Standard (MIL-STD) 883. In particular, the build-up of solder interconnections on conductive structures made of commercially available copper-containing PTF pastes and their mechanical characterization is novel. As well as the mechanical characterization of conductive structures, made of PTF pastes, on plasma-treated substrates and their grading using the MIL-STD 883. In addition, interconnections with silver-containing conductive structures are realized for comparison. Depending on the interconnection system, component mean shear forces of up to 31 N are achieved. While some systems meet the 1.25× criterion of MIL-STD 883, the majority of the systems investigated do not meet the 1.00× criterion. Hereby, the adhesion between the conductive structure and the substrate usually fails. Plasma pre-treatment shows an adhesion-increasing effect only for a proportion of substrate materials used, as does thermal aging. But thermal loads can also impair the adhesive strength.

Topic: Electrical and Thermal Properties of Materials
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Variation in Phytochemical, Morphological, and Ploidy Levels of Iranian <i>Thymus</i> Species

Abstract Thymus is one of the most important genera of the Lamiaceae family. This work was performed to assess inter and intra species variation, which is an indispensable prerequisite for the selection and the exploitation of the germplasm, using yield, secondary metabolites, and ploidy level criteria. Nineteen Iranian populations belonging to 11 Thymus species which includes T. vulgaris were used in this study. The results of cytological observations on the 19 populations revealed the three root‐tip chromosome numbers of 2 n =2 x =30, 2 n =4 x =56 or 60 (diploid and tetraploid). This study also presents the results of a two‐year field experiment that evaluates the agronomic and morphology of the 19 populations of Thymus spp. Cluster analysis grouped the populations into six groups and explained the relationships among ploidy levels, morphological traits, and essential oils (EOs). In general, diploid species belonged to the thymol chemotype, whilst carvacrol chemotype consistently dependent on the gene‐dosage effect. Thymus migricus , T. daenensis‐2 , T. serpyllum , and T. trautvetteri populations with diverse thymol background were the best selection as the parents to improve thymol in a breeding program. Moreover, dry and fresh weight criteria can be used to improve EO content in thyme. Achieving this goal would be expected by crossing T. migricus and T. daenensis‐2 . Finally, providing relevant information on the ploidy level of Thymus species, with emphasis on morphology and EO components variations, may be recommended for the selection of populations or species to improve bioactive components as well as morphological traits in future breeding programs.

Topic: Essential Oils and Antimicrobial Activity
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Assessment of risk factors for inappropriate empiric antibiotic therapy in patients with Gram-negative sterile site infection complicated by sepsis or septic shock

The association between the administration of inappropriate empiric antibiotic treatment (IEA) and an increased risk of hospital mortality has been consistently reported. This study explores pre-infection risk factors for IEA in patients with Gram-negative (GN) sterile site infections complicated by sepsis or septic shock. Retrospective cohort study at Barnes-Jewish Hospital (2010–2015). Risk factors including history of hospitalization, receipt of intravenous antipseudomonal antibiotics, and isolation of GN organisms 90 days prior to admission were collected. Process of care variables assessed included ICU admission, durations of mechanical ventilation, central venous catheter, and urinary catheter insertion, and antibiotic days prior to isolation of a GN pathogen(s). IEA was defined as receipt of antibiotic therapy that lacked in vitro activity against the identified pathogen(s) within the 24 hours of the culture being obtained. Multivariable logistic regression analysis (MVLRA) risk factor modeling that included IEA as the dependent outcome variable was conducted. 855 consecutive patients with first episode sepsis or septic shock were included. Compared with patients receiving appropriate empiric therapy (n = 715), variables significantly associated with IEA (n = 140) within 90 days prior to admission included recent hospitalization (23.1% v. 34.3%, P = 0.005), mean days of meropenem (0 v. 2.1, P = 0.010) and piperacillin-tazobactam (0 v. 1.6, P <0.001) therapy, and isolation of a GN organism(s) (8.4% v. 20.0%, P <0.001). Prior to isolation of the GN pathogen(s), median hospital (0 v. 6 days, P < 0.001) and ICU (0 v. 0 days, P < 0.001) length of stay, as well as the median duration of CVC dwell time (10 v. 17 days, P = 0.050) was associated with IEA. MVLRA identified isolation of a GN pathogen (AOR 3.432 95% CI 2.024-5.820, P <0.001) and days of piperacillin-tazobactam therapy (AOR 1.149 95% CI 1.061–1.245, P <0.001) in the 90 days prior to admission, as well as Charlson score (AOR 1.097 95% CI 1.023-1.177, p + 0.010) as independent risk factors for IEA. Consideration of risk factors prior to admission and prior to collection of a sterile site specimen appear to be critical when making empiric antibiotic decisions targeting GN pathogens in patients with sepsis or septic shock. S. Micek, Merck: Grant Investigator, Research grant.

Topic: Antibiotic Use and Resistance
Subfield: Applied Microbiology and Biotechnology
Field: Immunology and Microbiology
Domain: Life Sciences
STEROIDS DO NOT DECREASE POSTOPERATIVE PAIN OR NARCOTIC REQUIREMENTS FOLLOWING LIVER TRANSPLANTATION.

Ozcay, Figen; Canan, Oguz; Haberal, Aysegul; Yilmaz, Ugur; Karakayali, Hamdi; Haberal, Mehmet Author Information

Topic: Liver Disease and Transplantation
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences
The Papanicolaou Smear as a Diagnostic Tool in Male Trichomoniasis

No AccessJournal of Urology1 May 1972The Papanicolaou Smear as a Diagnostic Tool in Male Trichomoniasis Jack L. Summers and Manley L. Ford Jack L. SummersJack L. Summers More articles by this author and Manley L. FordManley L. Ford More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)61155-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1972 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 107Issue 5May 1972Page: 840-842 Advertisement Copyright & Permissions© 1972 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Jack L. Summers More articles by this author Manley L. Ford More articles by this author Expand All Advertisement PDF downloadLoading ...

Topic: Reproductive tract infections research
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Reducing Adiposity Indicators: How Much Exercise Dosage Is Needed?

Physical inactivity is considered a major factor contributing to the energy imbalance that leads to an excess of adiposity. There is a dearth of research regarding the exercise dosage required to reduce adiposity indicators in overweight minority girls. PURPOSE: To determine the exercise dosage required to reduce adiposity indicators. METHODS: Sixty-two overweight (BMI > 85th percentile for age and sex) Hispanic and African American girls (mean age (SD) 11.2 + 1.5 years) participated in either a three-week (2580 minutes of physical activity exposure) or four-week (3600 minutes of physical activity exposure) BOUNCE healthy lifestyle summer intervention. Participants wore accelerometers to assess the frequency and intensity of their physical activity levels each day of the BOUNCE interventions. Adiposity indicators (BMI, weight, body fat, and waist circumference) were taken pre- and post-intervention. Differences in daily minutes of MVPA over time were measured using a repeated measures analysis of variance. Differences between intervention doses were measured using repeated measures multivariate analysis of variance. RESULTS: Both BOUNCE interventions significantly increased MVPA levels (p = 0.020) over time. The four-week intervention had a significantly greater decrease in adiposity indicators (p = 0.006) over time as compared to the three-week intervention. Waist circumference displayed the most significant decrease (p = 0.001) with an observed power of 0.951. CONCLUSION: Interventions such as BOUNCE are effective in increasing MVPA and reducing abdominal obesity for minority girls, with greater benefit at a higher dose. The practical implications of these results can help shape future physical activity and obesity interventions.

Topic: Muscle metabolism and nutrition
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Presence of toxin-producing bacterial pathogens and associated risk factors in neonatal diarrhea of piglets on commercial sow farms in Vietnam

Background and Aim: Neonatal piglet diarrhea (NPD) remains a significant challenge in the swine industry, contributing to elevated pre-weaning mortality, reduced productivity, and increased economic losses. In Vietnam, despite the growing importance of commercial pig production, comprehensive studies investigating the epidemiology of NPD and associated bacterial pathogens are lacking. This study aimed to assess the prevalence of Escherichia coli, Clostridium perfringens, and Clostridioides difficile and to identify risk factors contributing to NPD on Vietnamese sow farms. Materials and Methods: A cross-sectional study was conducted on 40 commercial sow farms across North, Central, and South Vietnam between August and December 2023. Structured questionnaires captured data on farm characteristics, management practices, and health interventions. Fecal samples from symptomatic piglets aged 1–14 days were pooled and analyzed using multiplex quantitative polymerase chain reaction to detect virulence genes of E. coli (F4, F5, F6, LT), C. perfringens (alpha, beta, and epsilon toxins), and C. difficile (toxins A and B). Logistic and ordinal regression models were applied to assess associations between risk factors and pathogen prevalence. Results: All farms tested positive for at least one pathogen. C. perfringens was the most prevalent (97.37%), followed by E. coli (46.49%) and C. difficile (39.47%). Co-infections involving multiple pathogens were common (64.91%), with C. perfringens consistently present in all mixed infections. Key virulence genes detected included LT (35.96%), alpha toxin (95.61%), and toxin A (20.17%). Significant risk factors included farm type, region, weaning performance, and peripartum antibiotic administration route. Notably, farms using mixed-feed antibiotics exhibited higher E. coli prevalence. Larger farms and those practicing early piglet relocation also showed increased pathogen diversity. Conclusion: This study presents the first national-scale assessment of bacterial pathogens in NPD across Vietnamese sow farms. The findings highlight the high burden of toxin-producing bacteria, frequent co-infections, and multiple farm-level risk factors. Interventions such as targeted vaccination, optimized antibiotic use, improved weaning practices, and enhanced regional surveillance are essential for mitigating NPD impacts and improving piglet health outcomes in Vietnam. Keywords: bacterial toxins, Clostridioides difficile, Clostridium perfringens, Escherichia coli, farm management, multiplex quantitative polymerase chain reaction, neonatal piglet diarrhea, Vietnam, risk factors.

Topic: Clostridium difficile and Clostridium perfringens research
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Development of a source of accelerated neutral particles for the final purification of dielectric substrates

The paper discusses approaches to the improvement of sources for receiving streams of accelerated neutral particles, applied for final purification of dielectric surfaces. It is revealed that the most effective method of neutralization is based on the reflection of ions from a solid surface with their subsequent recharge. In the present work novel approach to the design of an accelerated neutral particles generator and the results of the study of its main characteristics are shown. Also a consistent cleaning process of a borosilicate glass using a developed source is demonstrated.

Topic: Advanced Sensor Technologies Research
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Green synthesis and antimicrobial activity of copper nanoparticles (Cu-NPS) by Piper longum fruit extract

Many applications of green synthesis in the field of environment and biomedicine aiming at decreasing the use of toxic chemicals through utilizing of plants which are safe. In this study, at 0.1 M concentration of copper sulfate (CuSO4.5H2O), CuNPs were prepared and identified by changing the blue color into green color (ethanolic extract) and from blue color to black color (water extract) and the spectrophotometric detection of ultraviolet and infrared spectra. X-Ray diffraction (XRD) pattern was utilized to confirm the crystal structure of CuNPs. The morphology and size of the CuNPs was measured by a high-resolution transmission electron microscope (HR-TEM). Energy dispersive X-ray (EDX) was used for identification of the elemental composition of CuNPs involving copper and oxygen. Field emission scanning electron microscopy (FESEM) was utilized to confirm the shape of prepared copper nanoparticles. In vitro antibacterial activity was tested using two methods including desk diffusion assay considering zones of inhibition and minimum inhibitory concentration (MIC) against six types of certain bacterial types (Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Staphylococcus aureus, Streptococcus pneumoniae and Enterococcus faecalis). The results showed potent inhibitory activity of copper nanoparticles (CuNPs) and water extract (Ext. 2) against all bacterial strains. KEY WORDS: Copper nanoparticles, Piper Longum, Extract, Synthesis, Antibacterial Bull. Chem. Soc. Ethiop. 2024, 38(6), 1653-1666. DOI: https://dx.doi.org/10.4314/bcse.v38i6.12

Topic: Piperaceae Chemical and Biological Studies
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
Hybrid level anharmonicity and interference-induced photon blockade in a two-qubit cavity QED system with dipole–dipole interaction

We theoretically study a quantum destructive interference (QDI)-induced photon blockade in a two-qubit driven cavity quantum electrodynamics system with dipole–dipole interaction (DDI). In the absence of dipole–dipole interaction, we show that a QDI-induced photon blockade can be achieved only when the qubit resonance frequency is different from the cavity mode frequency. When DDI is introduced the condition for this photon blockade is strongly dependent upon the pump field frequency, and yet is insensitive to the qubit–cavity coupling strength. Using this tunability feature we show that the conventional energy-level-anharmonicity-induced photon blockade and this DDI-based QDI-induced photon blockade can be combined together, resulting in a hybrid system with substantially improved mean photon number and second-order correlation function. Our proposal provides a nonconventional and experimentally feasible platform for generating single photons.

Topic: Quantum Information and Cryptography
Subfield: Artificial Intelligence
Field: Computer Science
Domain: Physical Sciences
Mining novel biosynthetic machineries of secondary metabolites from actinobacteria

ABSTRACT Secondary metabolites produced by actinobacteria have diverse structures and important biological activities, making them a useful source of drug development. Diversity of the secondary metabolites indicates that the actinobacteria exploit various chemical reactions to construct a structural diversity. Thus, studying the biosynthetic machinery of these metabolites should result in discovery of various enzymes catalyzing interesting and useful reactions. This review summarizes our recent studies on the biosynthesis of secondary metabolites from actinobacteria, including the biosynthesis of nonproteinogenic amino acids used as building blocks of nonribosomal peptides, the type II polyketide synthase catalyzing polyene scaffold, the nitrous acid biosynthetic pathway involved in secondary metabolite biosynthesis and unique cytochrome P450 catalyzing nitrene transfer. These findings expand the knowledge of secondary metabolite biosynthesis machinery and provide useful tools for future bioengineering.

Topic: Microbial Natural Products and Biosynthesis
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences