jimnoneill/paper-to-field-training huggingface dataset:
Extremity and caval deep venous thrombosis

Advances in supportive care have changed the landscape of clinical pediatrics from acute life-threatening conditions to more chronic diseases. Venous thromboembolism (VTE), comprising of deep venous and thrombosis (DVT) and pulmonary embolism (PE), traditionally considered as an acute and chronic disease of the elderly, is increasingly recognized in hospitalized children and has emerged as a significant public health burden. Although the incidence of pediatric thrombosis is lower than that in adults, over the last few decades it has been recognized that pediatric thrombosis has become a substantial health hazard and may be associated with significant morbidity and mortality. Additionally, the health-care burden of VTE may be particularly high for affected children, given the additional impact imposed on the child’s family members and by the much greater life expectancy compared with affected elderly adults. Evidence-based recommendations for management of pediatric thrombosis are still lacking, due to lack of large carefully conducted clinical trials and most recommendations are either directly extrapolated from adults or are based on consensus or expert opinions [1]. As the incidence of pediatric thrombosis increases and newer anticoagulant drugs make their way into the clinical field, investigators have felt the necessity for improved diagnostic testing, risk adapted treatment regimens and better definitions of outcome measures after pediatric thrombosis [2]. This chapter focuses on recent knowledge and current advances in pediatric extremity and caval thrombosis.

Topic: Venous Thromboembolism Diagnosis and Management
Subfield: Internal Medicine
Field: Medicine
Domain: Health Sciences
Why and how service quality perceptions impact consumer responses

Purpose This study aims to explore the relationship between the perceived quality of services provided by specialist physicians and patients' attitudinal responses along cognitive, emotive and conative levels. Design/methodology/approach The SERVQUAL model was used to evaluate the quality of the medical services. The data were collected in a survey of medium‐level executives enrolled in professional MBA and executive BA programs in Israel. Findings The study shows that patients' evaluations regarding service quality do affect significantly their attitudinal responses. It has also found out that service dimensions relating to anxiety reduction and the desires to reduce perceived risk, namely the Assurance and the Reliability dimensions are the most important for patients in these kinds of service encounters. Practical implications The study should encourage service managers of health care‐providing organizations to use these results to ensure higher patient satisfaction. These results indicate that, in these kinds of medical service encounters, physicians should explicitly recognize the role of service quality perceptions for anxiety reduction and incorporate as many anxiety‐reducing cues as possible in the environment of such interactions. Originality/value The research reinforces the importance of patients' perceptions of service quality in medical encounters. The study shows that such perceptions are relevant for patients in medical service encounters of the intermediate type where such patients are treated by specialist physicians. It shows that such perceptions affect the levels of patients' satisfaction from such encounters at both the cognitive and affective levels. They also affect their intentions to act following such encounters in the short, intermediate and long time spans.

Topic: Customer Service Quality and Loyalty
Subfield: Organizational Behavior and Human Resource Management
Field: Business, Management and Accounting
Domain: Social Sciences
Peroxisome proliferator-activated receptor-γ agonist rosiglitazone reduces secondary damage in experimental spinal cord injury

Objective To investigate the neuroprotective effects of rosiglitazone in a rat traumatic spinal cord injury (SCI) model. Methods Adult Sprague–Dawley rats ( n = 12/group) underwent laminectomy (sham), SCI, SCI and rosiglitazone treatment (2 mg/kg twice daily for 7 days), or SCI and saline injection (vehicle). SCI was induced via dural application of an aneurysm clip. Spinal cord apoptosis and levels of tumour necrosis factor-α (TNFα), interleukin (IL)-1β, myeloperoxidase (MPO) and the apoptosis-associated proteins B-cell leukaemia/lymphoma 2 (Bcl-2) and Bcl-2 associated X protein (Bax) were examined 24 h after SCI. Locomotor function was evaluated 3, 7, 10, 14 and 21 days after SCI. Results At 24 h after SCI, apoptosis and TNFα, IL-1β and MPO concentrations were significantly lower in the rosiglitazone group than in the vehicle and SCI groups. SCI resulted in an increase in Bax and a decrease in Bcl-2, which was reversed by rosiglitazone treatment. Rats in the rosiglitazone group had significantly better functional recovery than those in the vehicle and SCI groups. Conclusion Rosiglitazone signiﬁcantly improved functional recovery, probably via attenuation of the local inflammatory reaction and reduced apoptosis.

Topic: Spinal Cord Injury Research
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Effect of drying type on the physicochemical and phytochemical properties of young and mature Moringa oleifera leaves

Biochemical differences in response to dehydration methods in Moringa oleifera leaves were studied in moringa young and mature leaves. Sun drying, oven drying and Shade-drying were applied to leaves samples. After drying, leaves were powdered and subjected to physicochemical and phytochemical analyses. The results showed a lower concentration of physicochemical components in shade-dried moringa leaves excepted moisture content. However, shade-dried M. oleifera leaves showed higher phytochemical components than sun and Oven-drying leaves without significant difference (p˂ 0.05) between young and mature leaves. Furthermore, shade-dried drying leaves had better antioxidant activity (IC50 = 0.072 mg / ml for mature leaves and IC50 = 0.049 mg / ml for young leaves) than sun and oven-dried leaves. The shade-dried technique would be therefore the most recommended for preserving physicochemical and phytochemical quality. However, the higher moisture content of shade dried leaves could be a source of micro-organism proliferation when the powders are stored.

Topic: Moringa oleifera research and applications
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
T cell migration to synovial joints is not necessary for the development of proteoglycan-induced arthritis (95.5)

Abstract Rheumatoid arthritis (RA) is largely mediated by autoantibodies, the production of which is supported by autoreactive T cells. Previous reports in RA and its animal models also suggest that T cells present in the joints can locally propagate arthritis. To identify T cells migrating to the joints before and during arthritis development, we transferred fluorescence-labeled T cells and unlabeled antigen-presenting cells from BALB/c mice with proteoglycan-induced arthritis (PGIA) to syngeneic immunodeficient mice, and then monitored the recruitment of donor T cells in the ankle joints of the recipients using in vivo two-photon microscopy, immunohistochemistry, and flow cytometry. Despite the development of arthritis in the recipient mice, we found very few donor T cells in their joints after cell transfer. Furthermore, treatment of recipient mice with FTY720, an inhibitor of lymphocyte egress from lymphoid organs, which effectively depleted T cells in both peripheral blood and joints, failed to inhibit PGIA development. In contrast, arthritis did not occur in recipient mice after injection with donor cells depleted in T cells in vitro prior to transfer. Our results suggest that while lymphoid organ-homing T cells are required for the adoptive transfer of PGIA, the few T cells that migrate to the joints do not play a significant role in arthritis development. Work supported by the NIH and the Grainger Foundation.

Topic: Cell Adhesion Molecules Research
Subfield: Immunology and Allergy
Field: Medicine
Domain: Health Sciences
West Flank Coso FORGE: 33A-7 Image and Mud Log Data

Circumferential Borehole Imaging Log (CBIL) image log as DLIS file, and PDF mud log of well 33A-7 as part of the West Flank Coso, CA FORGE site.

Topic: Geological Modeling and Analysis
Subfield: Geochemistry and Petrology
Field: Earth and Planetary Sciences
Domain: Physical Sciences
OLDER AUSTRALIAN WOMEN’S HUMAN CAPITAL: PERCEPTIONS OF SKILL LEVELS AND PARTICIPATION IN LEARNING ACTIVITIES

Abstract While business cases for older workers’ employment stress their value it is well-known that they participate less in training activities than younger workers. Women are at particular risk of not accessing training opportunities. Drawing on a survey of 2500 women aged over 50 we report a fine-grained analysis of the types of training women were undertaking and the factors associated with participation in training. The analysis indicates that training is infrequently undertaken in preparation for a new job and large majorities of women see no need to and are not interested in retraining. This is observed across occupational groups, but more commonly among those with low educational levels. A lack of employer support is much less commonly reported as a barrier to older women’s participating in training. The findings suggest that it is primarily at women themselves that efforts aimed at promoting human capital development need to be directed.

Topic: Retirement, Disability, and Employment
Subfield: Demography
Field: Social Sciences
Domain: Social Sciences
Electrocatalyst Nanomaterials for Proton Exchange Membrane Fuel Cells

With the rapid depletion of fossil fuels and increasingly worsened environmental pollution caused by vast fossil-fuel consumption, there is high demand to make efficient use of energy and to seek renewable and clean energy sources alternative of fossil fuels to enable the sustainable development of our economy and society. Proton exchange membrane fuel cell is an efficient, silent and low pollution new electric power generator based oon two electrochemical reactions: the oxidation of hydrogen at the anode and the reduction of oxygen at the cathode.

Topic: Fuel Cells and Related Materials
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Spectral properties of the Newtonian potential field and their application in the interpretation of the gravity anomalies

Some spectral properties of the Newtonian potential field and of fields related to it by derivation processes are examined. Corresponding spectral techniques are proposed to treat several geophysical problems connected with the study of local gravity perturbation fields. In particular it is shown that, given the perturbing masses, such techniques allow the Bouguer and isostatic anomalies, the deflections of the vertical, as well as their upward and downward continuation, the geoidal height variations and, in general, the undulations of gravity equipotential surfaces, all to be obtained.

Topic: Geophysics and Gravity Measurements
Subfield: Oceanography
Field: Earth and Planetary Sciences
Domain: Physical Sciences
KMT Set7/9 affects genotoxic stress response via the Mdm2 axis

Genotoxic stress inflicted by anti-cancer drugs causes DNA breaks and genome instability. DNA double strand breaks induced by irradiation or pharmacological inhibition of Topoisomerase II activate ATM (ataxia-telangiectasia-mutated) kinase signalling pathway that in turn triggers cell cycle arrest and DNA repair. ATM-dependent gamma-phosphorylation of histone H2Ax and other histone modifications, including ubiquitnylation, promote exchange of histones and recruitment of DNA damage response (DDR) and repair proteins. Signal transduction pathways, besides DDR itself, also control expression of genes whose products cause cell cycle arrest and/or apoptosis thus ultimately affecting the sensitivity of cells to genotoxic stress. In this study, using a number of experimental approaches we provide evidence that lysine-specific methyltransferase (KMT) Set7/9 affects DDR and DNA repair, at least in part, by regulating the expression of an E3 ubiquitin ligase, Mdm2. Furthermore, we show that Set7/9 physically interacts with Mdm2. Several cancer cell lines with inverse expression of Set7/9 and Mdm2 displayed diminished survival in response to genotoxic stress. These findings are signified by our bioinformatics studies suggesting that the unleashed expression of Mdm2 in cancer patients with diminished expression of Set7/9 is associated with poor survival outcome.

Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Ipomoea batatas LOTID 304366

Plant Genetic Resource.<br>Taxonomy: Ipomoea batatas<br>Common name(s): Sweetpotato<br>Conserved by: Centro Internacional de la Papa (CIP), Peru<br>Local sample unique identifier: LOTID 304366<br>Method of creation: In-house copy<br>Date: 2019<br>Other identifiers: n/a,CIP 444126<br>Historical: Yes<br>Biological status: Traditional cultivar/landrace<br>MLS status: Included

Topic: Silymarin and Mushroom Poisoning
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Outbreak of Penicillinase-Producing Neisseria gonorrhoeae With an African Connection

Previous outbreaks of penicillinase-producing gonococcal infection in the United States have generally been attributed to importation of Southeast Asian strains. During July 1982 through July 1983, 110 cases of gonorrhea caused by penicillinase-producing strains were reported in metropolitan Atlanta, Georgia. Among the 53 infected women, 14 (26%) had pelvic inflammatory disease (PID). Compared to other infected women, those with PID experienced a greater delay from the time of last sexual exposure (19.1 vs 8.1 days) to receipt of appropriate antibiotic therapy (P less than .01). At least 22 prostitutes were involved in the outbreak. Sixteen (76%) of 21 isolates tested were serogroup 1A; 15 required arginine and proline for growth; and 17 (81%) possessed a 3.2 megadalton plasmid. Our data suggest that this outbreak was associated with both African and Southeast Asian strains.

Topic: Reproductive tract infections research
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Supporting student-written tests of gui programs

Tools like JUnit and its relatives are making software testing reachable even for introductory students. At the same time, however, many introductory computer sciences courses use graphical interfaces as an "attention grabber" for students and as a metaphor for teaching object-oriented programming. Unfortunately, developing software tests for programs that have significant graphical user interfaces is beyond the abilities of typical students (and, for that matter, many educators). This paper describes a framework for combining readily available tools to create an infrastructure for writing tests for Java programs that have graphical user interfaces. These tests are level-appropriate for introductory students and fit in with current approaches in computer science education that incorporate testing in programming assignments. An analysis of data collected during actual student use of the framework in a CS1 course is presented.

Topic: Teaching and Learning Programming
Subfield: Computer Science Applications
Field: Computer Science
Domain: Physical Sciences
Health Evaluation of Leatherback Turtles (Dermochelys coriacea) in the Northwestern Atlantic During Direct Capture and Fisheries Gear Disentanglement

Abstract Health evaluations were conducted in the northwestern Atlantic for 19 leatherback turtles, which included 12 turtles directly captured as part of a satellite telemetry study and 7 turtles entangled in fishing gear. Assessment included physical examination; determination of heart rate and respiratory rate; and hematologic, plasma biochemical, nutritional, toxicologic, parasitologic, and microbiological investigations. Significant differences were found between directly captured and entangled turtles for curved carapace length, curved carapace width, blood urea nitrogen, chloride, sodium, triglycerides, relative heterophil count, relative monocyte count, relative and absolute eosinophil count, pH, bicarbonate, lead, and beta-hydroxybutyrate. Directly captured turtles showed evidence of mild respiratory acidosis. Significant differences were found between sexes for curved carapace length, curved carapace width, total protein, globulin, sodium, relative monocyte count, gamma-globulin, and anion gap. Relatively high blood concentrations of selenium and cadmium were found in all turtles.

Topic: Turtle Biology and Conservation
Subfield: Nature and Landscape Conservation
Field: Environmental Science
Domain: Physical Sciences
Template induced chiral ordering in nematic liquid crystalline materials: A deuterium nuclear magnetic resonance study

Glancing angle deposition is used to create porous liquid crystal alignment layers with high aspect-ratio, three-dimensional features. We use solid-state deuterium nuclear magnetic resonance to determine the alignment of alpha deuterated 4′-pentyl-4-cyanobiphenyl in a 3.2μm thick SiO2 film comprised of independent, helical structures. Comparing measured spectra with models, we determine that the liquid crystalline molecules exhibit chiral ordering dictated by the features of the template films. In the plane of deposition the liquid crystalline molecules tilt away from the substrate normal at an average angle of 51°, which is commensurate with the helical features of the chiral template.

Topic: Liquid Crystal Research Advancements
Subfield: Electronic, Optical and Magnetic Materials
Field: Materials Science
Domain: Physical Sciences
Presence Over Time in Synchronous Communities of Inquiry

Abstract Abstract This study investigated the small-group, learner-led discussion process in synchronous discussions. Transcripts from online chats and face-to-face discussions were analyzed within the context of the Community of Inquiry framework to examine the relationship of teaching presence, social presence, and cognitive presence to one another and for evidence of changes in frequency of teaching, social, and cognitive presence over time. Findings suggest that social presence and cognitive presence are highly positively correlated and that teaching presence and social presence are moderately positively correlated in learner-led synchronous environments. The frequency of teaching, social, and cognitive presence did not change over time for either group. Findings also indicate that neither the group meeting online nor the group meeting face-to-face attained high levels of cognitive presence integration or resolution. ACKNOWLEDGMENT We thank Mona R. Simons for her assistance coding transcripts.

Topic: Online and Blended Learning
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
EFFECTS OF PLYOMETRIC TRAINING ON GRASS SURFACE AND CONCRETE SURFACE ON JUMPING PERFORMANCE AMONG VOLLEYBALL ATHLETES

The purpose of this study was to compare the effects of 4 weeks of plyometric training on grass surface group and concrete surface on jumping performance among volleyball athletes. The vertical jump was evaluated in two types of jump; squat jump (SJ) and countermovement jump (CMJ). The results of this study indicate that 4 weeks of intervention led to a significant improvement in post-tests of SJ and CMJ ( p &lt; 0.05) for both grass surface and concrete surface. However, in comparing the grass and concrete surfaces, there was no significant difference ( p &gt; 0.05). These findings suggest that plyometric training on different surfaces may be associated with similar training-induced effects on neuromuscular factors related to the efficiency of the stretch-shortening cycle.

Topic: Sports Performance and Training
Subfield: Orthopedics and Sports Medicine
Field: Medicine
Domain: Health Sciences
CCDC 821516: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Primary Power and Power Density Analysis.

This memorandum presents a simplified analysis of the active system power requirements for new submarine sonar. The analysis was performed in the new submarine sonar group for the purpose of indicating approximate primary power and transducer design requirements. The primary power and the power density required to produce a specific source level are functions of the geometry of the array, the efficiency of power conversion and the characteristic impedance of the water. The efficiency of power conversion is the product of efficiencies of the transducer and the power amplifier. The effect of the ordinary variation in the impedance of the ocean is insignificant.

Topic: Hermeneutics and Narrative Identity
Subfield: Philosophy
Field: Arts and Humanities
Domain: Social Sciences
Is Stimulant Treatment in Children and Adolescents with Mood Dysregulation Associated with Adverse Outcomes?

The aim of this paper is to examine effects of stimulant treatment in children and adolescents with high levels of emotional dysregulation in a psychiatric outpatient clinic. Subjects were referred children and adolescents 6-17 years of age who presented to a child psychiatric outpatient clinic between September 2016-November 2021 and received a prescription for a stimulant medication. Children were stratified into those with low and high levels of emotional dysregulation as defined by an aggregate T-score of &amp;lt;180 or &amp;ge;210 on the combined Attention Problems, Aggressive Behavior, and Anxious/Depressed subscales of the Child Behavior Checklist (CBCL; CBCL-AAA). We analyzed patient prescription, diagnosis, and hospital visit data extracted from the electronic medical record from any time prior to referral through three months after referral. Patients with higher CBCL-AAA scores at clinic intake had a significantly different medication and diagnosis profile and were more likely to have a higher dosage of stimulants than patients with lower scores. These patients also were more likely to receive an additional medication class during follow-up, which was driven by second-generation antipsychotics (SGAs). Emergency room visits and inpatient psychiatric admissions were rare but present only in the group with higher CBCL-AAA scores. These results suggest that stimulant treatment affects youth with high versus low levels of emotional dysregulation adversely with a need for higher stimulant doses and treatment augmentation with SGAs. The CBCL may be a useful tool for identifying poor outcomes with stimulant treatment.

Topic: Attention Deficit Hyperactivity Disorder
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
CCDC 1001523: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences