jimnoneill/paper-to-field-training huggingface dataset:
Product Recommendation based on Customer Segmentation Engine

In today's competitive market, it's critical to comprehend customer behavior and categorize customers according to their demographics and purchasing habits. This is an important part of consumer segmentation since it enables marketers to better customize promotional, marketing, and product development tactics to different audience groups. Customer segmentation is the practice of dividing consumers into groups based on common characteristics, spending habits, and purchasing patterns. Customer segmentation is a technique for determining how to interact with customers in various categories to maximize the value of each client to the company. Customer segmentation can help marketers reach out to each customer in the most effective way possible. Customer segmentation study makes use of a large amount of customer data to properly identify distinct groups of consumers based on behavioural, demographic, and other criteria. K-means clustering is an unsupervised machine learning approach, as opposed to supervised ones. When we have unlabeled data, we employ this method. Unlabeled data is information that hasn't been assigned to any of the available categories or groupings. Different techniques are applied in customer segmentation to determine the optimal number of clusters, but each approach has its own drawbacks, such as the DBSCAN algorithm failing in the scenario of changing density clusters. RFM research is based on historical data rather than future projections. The Hierarchical Clustering technique can never erase what has already been done, and therefore necessitates the use of labeled data. Whereas the K-means method ensures convergence, warm-starts the centroid's locations, and quickly adapts to new and form optimal cluster numbers.

Topic: Customer churn and segmentation
Subfield: Marketing
Field: Business, Management and Accounting
Domain: Social Sciences
SOIL EROSION RISK IN BARAK PLAIN FROM THE PERSPECTIVE OF THE ENVIRONMENTALISTS

This study aimed to determine the soil erosion risk in agricultural areas of Barak Plain (Gaziantep). The magnitude of soil erosion risk was investigated by the application of Revised Universal Soil Loss Equation and Geographic Information Systems and results were displayed as erosion risk maps. From the research area, 14 stations were determined. Soil erosion risk and several physicochemical properties of soils were investigated. The results showed a high erodibility factor and at the same time a very low content of organic matter in the soils of the studied area. This study indicated the necessity of taking more efficient precautions against erosion urgently

Topic: Soil and Environmental Studies
Subfield: Soil Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Forensic neurobiology underlying violent criminal behavior

Violent criminal behavior may be a sequela of functionally and structurally compromised prefrontal and corticolimbic cortices. These anatomically distinct yet functionally integrated regions of the human brain confer qualities of moral sensibility and intentionality of action. Criminal behavior leading to conviction necessitates the commission of a prohibited act, actus reus, coincidentally occurring with a guilty state of mind, mens rea. Sentencing determinations markedly differ for those who intentionally violate compared to reckless acts and such outcomes can be critically life-impactful. However, making inferential assessments about an aggressor’s mental state can be a challenging task for legal experts. This meta-analysis reviews how the functional somatotopy of brain regions associated with aggression can be forensically assessed to contextualize violent criminal behavior to facilitate legal processes. Because brain scans have diagnostic credibility, by extension, they are increasingly becoming persuasive forensic evidence. A centralized neuroimaging database may emerge as a game-change for legal processes. The intercalated framework of neurolaw uniquely offers great power to elucidate criminological factors within the statute.

Topic: Psychopathy, Forensic Psychiatry, Sexual Offending
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Ballet Educational Academic Model. Advocacy for an Epistemological Approach

This paper includes excerpts from the opening section of the author's doctoral dissertation on pedagogical action research, successfully defended in September 2023 at Babeș-Bolyai University in Cluj-Napoca. The PhD action research conducted an epistemological inquiry aimed at redefining ballet education for the contemporary era. It introduced innovative methods for identifying, analyzing, and rectifying systemic shortcomings within the ballet canon. Moreover, it proposed pathways for a fundamental shift in the perception of ballet, advocating for its recognition as a dynamic field that integrates art, profession, science, education, and lifestyle.

Topic: Sports and Physical Education Studies
Subfield: Life-span and Life-course Studies
Field: Social Sciences
Domain: Social Sciences
CMOS‐based high‐order LP and BP filters using biquad functions

This study proposes the complementary metal–oxide–semiconductor (CMOS)‐based current‐modehigh‐order active low‐pass (LP) and band‐pass (BP) filters using biquadfunctions. The passive RLC Chebyshev ladder filters were used as the prototype,and the mesh‐ and nodal‐analysis methods to derive the biquad functions. TheCMOS‐based transistor‐level biquad circuits were subsequently realised from thebiquad functions. The high‐order active LP and BP ladder filters were thensynthesised from an amalgamation of the biquad circuits. Simulations werecarried out to verify the performance and functionality of the LP and BP ladderfilters. The results revealed that the proposed ladder filters were operable inthe high‐frequency range and electronically tunable, given a low‐voltage supplyof 1 V for the entire circuit. The proposed filters could also achieve the LPfrequency response of 300 kHz–30 MHz and BP centre frequency of 200 kHz−20 MHzby means of the bias current ( I B ) manipulation from1 to 100 µA. Moreover, the multi‐tone simulations were undertaken to assess thefiltering performance of the proposed filters and the results are agreeable withthe design specifications.

Topic: Analog and Mixed-Signal Circuit Design
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Analysis of Aroma Compounds of Heated Fats from Wagyu Beef and Other Cattle Using Headspace SPME

市販の和牛,交雑牛,乳牛および輸入牛(豪州産)の皮下脂肪(SF)と筋内脂肪(IF)について,固相マイクロ抽出(SPME)した加熱香気成分を比較した.その結果SFでは,和牛はアルデヒド,アルコール類が,交雑牛ではアルカン,芳香族化合物類が,輸入牛はエステル類が多かった.和牛香に寄与するラクトン類(γ-あるいはδ-Cn (nは炭素数)と表す)については,和牛ではγ-C7,C8,C9が,乳牛と輸入牛ではγ-C10,C12,δ-C10が有意に多かった.交雑牛のラクトン類組成は乳牛に似ていた. IFでは和牛はアルカン,芳香族化合物,エステル類が多く,輸入牛はアルコール,アルデヒド類が多かった.いずれの牛でもSFとIFで香気成分の構成割合が異なっていた.ラクトン類は和牛のγ-C4,C6がその他の牛より多い傾向にあり,逆にδ-C6,γ-C7,C8,C9はその他の牛より少ない傾向にあった.交雑牛のラクトン類組成は乳牛と似ていた.

Topic: Meat and Animal Product Quality
Subfield: Animal Science and Zoology
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Recent Developments in EU Competition Law

It was a great pleasure to be asked to deliver a Lectio Magistralis in Rome on 23 April 2015 as part of the celebrations of the first year of the Revista Italiana di Antitrust. In my lecture I drew attention to four particular topics: the European Commission’s recent enforcement efforts in relation to cartels; the latest judgments of the Court of Justice on the meaning of a restriction of competition by object; vertical agreements; and the abuse of dominance.

Topic: European and International Law Studies
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
A Case of Triple-Infection with SARS-CoV-2, Chikungunya, and Dengue Fever in a Returning Traveler

Chikungunya (CHIKV) and dengue (DENV) fever are caused by arboviruses with a shared vector and often overlap in tropical endemic areas. COVID-19, caused by the SARS-CoV-2 virus, has a similar presentation to CHIKV and DENV. The case of a 39-year-old woman with a triple viral infection (DENV, CHIKV, and SARS-CoV-2) is presented. Co-infection with endemic viruses post-travel is likely underreported due to overlapping clinical presentations and timelines. Awareness of illness in returning travelers and prompt co-infection diagnosis are needed to optimize patient outcomes.

Topic: Mosquito-borne diseases and control
Subfield: Public Health, Environmental and Occupational Health
Field: Medicine
Domain: Health Sciences
Beta‐adrenoceptors and human skeletal muscle characterisation of receptor subtype and effect of age.

1. Rectus abdominis muscle biopsies were obtained from 28 patients undergoing abdominal surgery. In membranes prepared from these biopsies beta‐adrenoceptor binding was examined. The apparent affinity (KD) and the density (Bmax) of the receptors for the radioligand (−)− [125I]cyanopindolol were 28.5 +/‐ 2.7 (pM) and 25.9 +/‐ 2.1 (fmol mg‐1 protein) (mean +/‐ s.e. mean) respectively. In forceps biopsies from vastus lateralis muscle from four healthy volunteers the values for KD and Bmax were 22.5 +/‐ 4.4 (pM) and 16.4 +/‐ 2.2 (fmol mg‐1 protein). The binding characteristics for the radioligand were similar in the biopsies from the two muscle sites. 2. Inhibition of the radioligand binding by the selective beta 2‐adrenoceptor antagonist ICI 118551 (KI = 117 +/‐ 45 nM) and selective beta 1‐adrenoceptor antagonist metoprolol (KI = 15229 +/‐ 5046 nM) suggests the dominance of beta 2‐ adrenoceptor subtype in human skeletal muscle. 3. There were no significant differences in the skeletal muscle beta‐adrenoceptor densities or affinities between the young and older patients.

Topic: Pharmacological Effects and Assays
Subfield: Animal Science and Zoology
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Improving the Quality of Hotel Feasibility Studies: Evaluating Potential Opportunities for Hotel Development and Acquisition in University Towns

Hotel developers and purchasers searching for new opportunities have been advised to consider hotels in university towns because, among other reasons, universities provide a stable source of lodging demand. This study analyzes the performance and stability since 1990 of hotels in 27 cities dominated by a major university. This study finds that lodging demand in university towns is more stable than U.S. averages. This study also evaluates factors that lodging feasibility analysts should consider when studying proposed hotel development or acquisition in markets dominated by a university. Significant predictors of lodging demand include city employment and population trends, as would be expected. Interestingly, university grant funding and graduate student population also should be considered by feasibility analysts because of their strong predictive capability. The results of this study may be generalizable for analysts evaluating university-related lodging demand in general, not just in university towns.

Topic: Diverse Aspects of Tourism Research
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
[Effect of qianyang recipe on correlated indices of hypertension rats of gan-yang hyperactivity syndrome].

QYR could relieve GYHS rats' symptoms such as facial hotness, irritability, dry hair, and so on, and decrease the systolic pressure. Decreased Ang II level might be one of its mechanisms.

Topic: Traditional Chinese Medicine Studies
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Mutated GM‐CSF‐based CAR‐T cells targeting CD116/CD131 complexes exhibit enhanced anti‐tumor effects against acute myeloid leukaemia

Abstract Objectives As the prognosis of relapsed/refractory (R/R) acute myeloid leukaemia (AML) remains poor, novel treatment strategies are urgently needed. Clinical trials have shown that chimeric antigen receptor (CAR)‐T cells for AML are more challenging than those targeting CD19 in B‐cell malignancies. We recently developed piggyBac ‐modified ligand‐based CAR‐T cells that target CD116/CD131 complexes, also known as the GM‐CSF receptor (GMR), for the treatment of juvenile myelomonocytic leukaemia. This study therefore aimed to develop a novel therapeutic method for R/R AML using GMR CAR‐T cells. Methods To further improve the efficacy of the original GMR CAR‐T cells, we have developed novel GMR CAR vectors incorporating a mutated GM‐CSF for the antigen‐binding domain and G4S spacer. All GMR CAR‐T cells were generated using a piggyBac ‐based gene transfer system. The anti‐tumor effect of GMR CAR‐T cells was tested in mouse AML xenograft models. Results Nearly 80% of the AML cells predominant in myelomonocytic leukaemia were found to express CD116. GMR CAR‐T cells exhibited potent cytotoxic activities against CD116 + AML cells in vitro . Furthermore, GMR CAR‐T cells incorporating a G4S spacer significantly improved long‐term in vitro and in vivo anti‐tumor effects. By employing a mutated GM‐CSF at residue 21 (E21K), the anti‐tumor effects of GMR CAR‐T cells were also improved especially in long‐term in vitro settings. Although GMR CAR‐T cells exerted cytotoxic effects on normal monocytes, their lethality on normal neutrophils, T cells, B cells and NK cells was minimal. Conclusions GMR CAR‐T cell therapy represents a promising strategy for CD116 + R/R AML.

Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Dynamic changes in absolute immature platelet count suggest the presence of a coexisting immune process in the setting of thrombotic thrombocytopenic purpura

BACKGROUND Previous studies have indicated the usefulness of absolute immature platelet counts (A‐IPCs) in the management and diagnostic algorithm of thrombotic thrombocytopenic purpura (TTP). Specifically a threefold increase in A‐IPC from baseline may be diagnostic of TTP. Here, A‐IPC was used to understand a coexisting immune dysregulation complicating TTP treatment. CASE REPORT A 17‐year‐old previously healthy female was admitted with altered mental status, petechiae, anemia, thrombocytopenia, and schistocytes on peripheral smear. Daily therapeutic plasma exchange (TPE) and corticosteroids were started for suspected TTP supported by ADAMTS13 activity of less than 5%, inhibitor more than 8, and more than threefold A‐IPC increase from baseline post‐TPE initiation. Despite daily TPE, the patient had significant and unexpected decreases in platelet (PLT) counts and A‐IPCs during her hospital course. After each PLT count decline, response to TPE and immunosuppression led to increasingly prolonged count recovery with subsequent episodes. Decreases in both PLTs and A‐IPCs indicated that both mature and immature PLTs were being cleared from circulation. Recovery occurred once A‐IPC dynamics indicated restored negative feedback in relation to PLT count. CONCLUSION Serial monitoring of A‐IPC dynamics was indicative of coexisting processes in the setting of ADAMTS13 deficiency. Uncoupling of the expected A‐IPC and PLT count seen in TTP suggested the presence of such an immune process in addition to TTP with high ADAMTS13 inhibitor. Monitoring of A‐IPC is a clinically valuable, rapid, and noninvasive thrombopoietic measurement when TTP is suspected.

Topic: Complement system in diseases
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Concurrent administration of flunisolide nasal solution with beclomethasone dipropionate bronchial aerosol in patients with both rhinitis and asthma.

Twenty patients with asthma controlled by oral inhalations of beclomethasone dipropionate (400 micrograms/day) were treated for concurrent rhinitis by the addition of flunisolide nasal solution (300 micrograms/day) and its placebo for three weeks each in a randomized, double-blind, crossover trial. Flunisolide produced a statistically significant benefit for each symptom parameter: sneezing (p = 0.013), runny nose (p = 0.027), stuffy nose (p = 0.005 and over-all severity (p = 0.005). More concomitant rhinitis medication was used during placebo treatment (p = 0.069). Seventy percent of the patients had "total" or "substantial" control of nasal symptoms with flunisolide vs. 45% with placebo (p less than 0.01). Eighty percent felt that flunisolide was either the only active drug or the more active (p less than 0.01). Three morning plasma cortisol determinations during the last week of each treatment period showed no drug-related effect. No nasal cultures were positive for Candida; the incidence of positive pharyngeal; cultures did not vary significantly. Adverse reactions consisted primarily of nasal burning and stinging; none was serious. In this group of twenty patients using inhalations of beclomethasone dipropionate for asthma, accompanying perennial rhinitis was substantially controlled by 300 micrograms of flunisolide nasal solution per day without significant additive effect on plasma cortisol levels or the incidence of overgrowth of Candida.

Topic: Respiratory and Cough-Related Research
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
&lt;i&gt;In vitro&lt;/i&gt; susceptibility testing of phytochemicals from essential oils against &lt;i&gt;Prototheca&lt;/i&gt; species

Phytochemicals isolated from essential oils are effective alternatives for inhibiting microbial pathogens. Bovine protothecal mastitis is the cause of a reduction in milk production and the secretion of thin, watery milk with white flakes. In the present study, we performed in vitro susceptibility testing of the phytochemicals carvacrol, citral, and thymol in Prototheca strains isolated from cases of protothecosis in small animals and cow feces. The susceptibility of the algae to carvacrol, citral, and thymol was assessed using the modified CLSI M27-A3 broth microdilution method. The ranges of the minimum inhibitory concentrations (MIC%) of the phytochemicals in all isolates were 0.03% to 0.125% for carvacrol, 0.03% to 0.25% for citral, and 0.06% to 0.25% for thymol. Based on these results, carvacrol, citral, and thymol appear effective against Prototheca species at the tested concentrations, and may thus be useful for environmental disinfection in barns.

Topic: Essential Oils and Antimicrobial Activity
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Experimental Evaluation of Large Spacing Compound Angle Full Coverage Film Cooling Arrays: Adiabatic Film-Cooling Effectiveness

PROCEEDINGS PAPER Experimental Evaluation of Large Spacing Compound Angle Full Coverage Film Cooling Arrays: Adiabatic Film-Cooling Effectiveness Greg Natsui, Greg Natsui University of Central Florida, Orlando, FL Search for other works by this author on: This Site PubMed Google Scholar Roberto Claretti, Roberto Claretti University of Central Florida, Orlando, FL Search for other works by this author on: This Site PubMed Google Scholar Jayanta S. Kapat, Jayanta S. Kapat University of Central Florida, Orlando, FL Search for other works by this author on: This Site PubMed Google Scholar Michael E. Crawford, Michael E. Crawford Siemens Energy Inc., Orlando, FL Search for other works by this author on: This Site PubMed Google Scholar Glenn Brown, Glenn Brown Siemens Energy Inc., Orlando, FL Search for other works by this author on: This Site PubMed Google Scholar Ken Landis Ken Landis Florida Turbine Technology, Jupiter, FL Search for other works by this author on: This Site PubMed Google Scholar Author Information Greg Natsui University of Central Florida, Orlando, FL Roberto Claretti University of Central Florida, Orlando, FL Jayanta S. Kapat University of Central Florida, Orlando, FL Michael E. Crawford Siemens Energy Inc., Orlando, FL Glenn Brown Siemens Energy Inc., Orlando, FL Ken Landis Florida Turbine Technology, Jupiter, FL Paper No: HT2012-58131, pp. 737-743; 7 pages https://doi.org/10.1115/HT2012-58131 Published Online: July 24, 2013

Topic: Turbomachinery Performance and Optimization
Subfield: Aerospace Engineering
Field: Engineering
Domain: Physical Sciences
Composition and physiological functions of the porcine colostrum

Abstract The first secretion, 24‐h post parturition of the mammary glands of sows, known as colostrum, is high in protein and low in lactose and fat. As a consequence of an insufficient ingestion of colostrum, more than 50% of piglets fail to reach weaning and die. The composition and some functions of colostrum have been previously reported. For example, colostrum carbohydrates consist of mainly lactose. Lipids in the colostrum are mostly triacylglycerols, but &lt;1% is fatty acids, which may act as homeostasis regulators. Similarly, proteins are found mostly as casein and whey, the latter being ≥80% immunoglobulins. Colostrum‐derived immunoglobulins and bioactive proteins such as azurocidin help the immune system of the piglet fend off infections. In addition, leukocytes and exosomes are other minor but nonetheless equally crucial bioactive components in the porcine colostrum. Modern pig farming has achieved increases in pig productivity and litter size, but this has been accomplished in detriment of the health and the survival rate of piglets. Therefore, porcine colostrum is now even more important in pig farming. In the present review, we discuss the current knowledge on the composition and physiological functions of the porcine colostrum and briefly propose future research directions.

Topic: Animal Virus Infections Studies
Subfield: Animal Science and Zoology
Field: Agricultural and Biological Sciences
Domain: Life Sciences
On global behavior of a some SIR epidemic model based on the Poincaré compactification

It is important to study the global behavior of solutions to systems of ordinary differential equations describing the transmission dynamics of infectious disease. In this paper, we present a different approach from the Lyapunov function used in most of the study. This approach is based on the Poincaré compactification. We then apply the method to an SIR endemic model as a test case, and discuss its effectiveness and the potential applications of this approach. In addition, we refine the discussion of dynamics near the equilibrium, derive the asymptotic behavior, and mention its relation to the basic reproduction number.

Topic: Mathematical and Theoretical Epidemiology and Ecology Models
Subfield: Public Health, Environmental and Occupational Health
Field: Medicine
Domain: Health Sciences
Wine makings by the yeast isolated from raisin

The authors expected that the raisin-origin Iizuka yeast would have potential faculties for wine makings, and performed the new wine making by this yeast. The Iizuka yeast revealed the enough sulfite tolerance for the wine makings and the suitable concentration of sulfite to add was up to 100 ppm. The wine made from whole normal grapes by the yeast showed the certain tendency to higher non-volatile compounds and lower total acidity than commercial control wine. Especially, the red wine produced using Muscat berry A contained the higher levels of alcohol, non-volatile compounds, and reducing sugar. The analysis of aromas of the wines by the application of an aroma extract dilution analysis (AEDA) showed high flavor dilution (FD) factor ranges of certain compounds which can be supposed as 3-methylbutanol and β-damascenone. These results indicated that the Iizuka yeast has the potentially enough faculties for the wine making. Careful and appropriate improvements shall be necessary to make more marvelous wine that is featuring the faculties of the Iizuka yeast.

Topic: Fermentation and Sensory Analysis
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences