jimnoneill/paper-to-field-training huggingface dataset:
Effect of polar substituents upon carbon-13-carbon-13 coupling constants

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of polar substituents upon carbon-13-carbon-13 coupling constantsWilliam M. Litchman and David M. GrantCite this: J. Am. Chem. Soc. 1967, 89, 25, 6775–6776Publication Date (Print):December 1, 1967Publication History Published online1 May 2002Published inissue 1 December 1967https://pubs.acs.org/doi/10.1021/ja01001a076https://doi.org/10.1021/ja01001a076research-articleACS PublicationsRequest reuse permissionsArticle Views33Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Topic: Molecular spectroscopy and chirality
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Dimerization of lactase-phlorizin hydrolase occurs in the endoplasmic reticulum, involves the putative membrane spanning domain and is required for an efficient transport of the enzyme to the cell surface.

Analysis of the quaternary structure of human intestinal lactase-phlorizin hydrolase (LPH) by chemical cross-linking and sucrose-gradient centrifugation reveals that the brush border form of LPH (LPH beta; 160-kDa) is a homodimeric molecule. Dimerization ensures in the ER when LPH is still exclusively found as an uncleaved mannoserich precursor (pro-LPHb; 215-kDa). This is supported by the following observations. (i) Biosynthetically labeled intestinal biopsy specimens as well as transfected COS-1 cells expressing pro-LPH contain monomeric and dimeric forms of pro-LPHb; the complex glycosylated pro-LPH (pro-LPHc; 230-kDa) as well as the cleaved mature LPH beta species in intestinal biopsy samples are discerned exclusively as dimers. (ii) Dimeric forms of pro-LPHh could be also detected when cells were biosynthetically labeled at 15 degrees C, at which temperature the egress of pro-LPH from the ER is blocked. Dimerization is essential for the transport competence of pro-LPH and is strongly associated with the presence of an intact transmembrane domain. Mutant pro-LPH-mact lacking the complete transmembrane domain persists as a monomeric, mannose-rich and transport-incompetent molecule that is not secreted into the exterior milieu, accumulates most likely in the ER and is ultimately degraded. Further, deletion of the cytoplasmic tail in the pro-LPH-ct mutant leads to marked reduction in the proportion of dimeric as well as complex glycosylated pro-LPH-ct. Finally, dimerization is linked to the acquisition of LPH to its biological function, since only dimers of wild type pro-LPH or pro-LPH-ct are enzymatically active, while their monomeric counterparts as well as pro-LPH-mact are not.

Topic: Digestive system and related health
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Impact of Panicum maximum substitution for fish meal in Nile tilapia (Oreochromis niloticus) diets: effects on growth performance, body composition, feed efficiency, and nutrient digestibility

In our research, we explored how effective it is to use Panicum maximum meal (PMM) in place of fish meal for young Nile tilapia's food. We formulated five different meals that all had the same levels of protein and energy but varied in how much PMM they contained, replacing 0, 25, 50, 75, or 100% of the fish meal protein. For 75 days, we fed these specially prepared meals to young fish (each meal was given to 30 fish starting with an average weight of about 10.2 grams). We looked into how this change affected their growth, how well they used the food, their body makeup, and how well they could digest the nutrients. Compared to the usual fish meal diet, replacing half of the fish meal with PMM didn't negatively impact their growth or how efficiently they turned food into body mass, even though their ability to digest solid food components went down significantly. Fish that ate the diet with the most Corn Gluten Meal (CGM) had too much triglyceride in their blood, and any diet with more than half CGM led to too much cholesterol. Examining the fish that were given a diet with 50% CGM, we noticed they retained more protein and less fat in their bodies. A mathematical model suggested that the optimal growth rate for young Nile tilapia occurs when their diet includes up to a 25% substitution of PMM. Our study shows that CGM can effectively replace up to half of the protein from fish meal in Nile tilapia diets.

Topic: Aquaculture Nutrition and Growth
Subfield: Aquatic Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Supernova Bounds on keV-mass Sterile Neutrinos

Sterile neutrinos of keV masses are one of the most promising candidates for the warm dark matter, which could solve the small-scale problems encountered in the scenario of cold dark matter. We present a detailed study of the production of such sterile neutrinos in a supernova core, and derive stringent bounds on the active-sterile neutrino mixing angles and sterile neutrino masses based on the standard energy-loss argument.

Topic: Dark Matter and Cosmic Phenomena
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
&lt;title&gt;Digitization and metric conversion for image quality test targets: Part II&lt;/title&gt;

A common need of the INCITS W1.1 Macro Uniformity, Color Rendition and Micro Uniformity <i>ad hoc</i> efforts is to digitize image quality test targets and derive parameters that correlate with image quality assessments. The digitized data should be in a colorimetric color space such as CIELAB and the process of digitizing will introduce no spatial artifacts that reduce the accuracy of image quality parameters. Input digitizers come in many forms including inexpensive scanners used in the home, a range of sophisticated scanners used for graphic arts and scanners used for scientific and industrial measurements (e.g., microdensitometers). Some of these are capable of digitizing hard copy output for image quality objective metrices, and this report focuses on assessment of high quality flatbed scanners for that role. Digitization using flatbed scanners is attractive because they are relatively inexpensive, easy to use, and most are available with document feeders permitting analysis of a stack of documents with little user interaction. Other authors have addressed using scanners for image quality measurements. This paper focuses (1) on color transformations from RGB to CIELAB and (2) sampling issues and demonstrates that flatbed scanners can have a high level of accuracy for generating accurate, stable images in the CIELAB metric. Previous discussion and experimental results focusing on color conversions had been presented at PICS 2003. This paper reviews the past discussion with some refinement based on recent experiments and extends the analysis into color accuracy verification and sampling issues.

Topic: 3D Surveying and Cultural Heritage
Subfield: Geology
Field: Earth and Planetary Sciences
Domain: Physical Sciences
Safety Evaluation of a Transfer Station Based on Gray Incidence Appraisal Method

As numerous passengers gather in a transfer station, ensuring the safety of the transfer station is of great significance. Through the analysis of the traditional safety evaluation of transfer station and the evaluation index system based on the safety assessment of the changes in passenger traffic of the transfer station, the proposed gray correlation degree evaluation method based on the coefficient of variation empowered is proposed. The method is a variation coefficient method, gray relational degree evaluation method combining method. Empowerment with a coefficient of variation of the evaluation index is an objective method of empowerment and will not be influenced by subjective factors. Gray relevant coefficient evaluation did not ask how much of the sample size and does not need the typical distribution of a small amount of calculation, and for the safety assessment of the transfer station indicators there may be overlapping or related issues such as gray correlation degree evaluation method not be affected. This paper takes the safety evaluation method of combining gray correlation grade analysis and the coefficient of variation method to evaluate the safety of the transfer station. And a transfer station is taken for evaluated. Based on the results of local investigation, conduct the safety evaluation by applying the methods above and obtain transfer station's final evaluation results.

Topic: Evaluation Methods in Various Fields
Subfield: Ecological Modeling
Field: Environmental Science
Domain: Physical Sciences
Scalable Analysis of Authentic Viral Envelopes on FRONTERA

Enveloped viruses, such as SARS-CoV-2, infect cells via fusion of their envelope with the host membrane. By employing molecular simulations to characterize viral envelopes, researchers can gain insights into key determinants of infection. Here, the Frontera supercomputer is leveraged for large-scale modeling and analysis of authentic viral envelopes, whose lipid compositions are complex and realistic. Visual Molecular Dynamics (VMD) with support for MPI is employed, overcoming previous computational limitations and enabling investigation into virus biology at an unprecedented scale. The techniques applied here to an authentic HIV-1 envelope at two levels of spatial resolution (29 million particles and 280 million atoms) are broadly applicable to the study of other viruses. The authors are actively employing these techniques to develop and characterize an authentic SARS-CoV-2 envelope. A general framework for carrying out scalable analysis of simulation trajectories on Frontera is presented, expanding the utility of the machine in humanity’s ongoing fight against infectious diseases.

Topic: Lipid Membrane Structure and Behavior
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Feasibility of a Group-Based Purpose Renewal Intervention for Cancer Survivors Via Zoom

The COVID-19 pandemic contributed to both existential distress and the rapid adoption of telehealth-based services. Little is known about the feasibility of delivering group occupational therapy intervention to address purpose-related existential distress via face-to-face synchronous videoconferencing. The objective of the study was to evaluate the feasibility of providing a purpose in life renewal intervention to breast cancer survivors via Zoom. Descriptive data were collected on acceptability and implementability of the intervention. Limited-efficacy testing involved a prospective pretest–posttest study where participants with breast cancer ( n = 15) received an eight-session purpose renewal group intervention plus a Zoom tutorial. Participants completed standardized measures of meaning and purpose at pretest and posttest, and a forced-choice Purpose Status Question. The purpose renewal intervention was acceptable and implementable via Zoom. Pre–post changes in purpose in life were not statistically significant. Group-based purpose in life renewal intervention is acceptable and implementable when delivered via Zoom.

Topic: Cancer survivorship and care
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Absenteeism Control Programs

An absenteeism control program can reduce employee absenteeism, thereby reducing company expenses, improving productivity, and bringing workers back to work sooner. A survey of Cohn's suggests that many companies in the United States lack absenteeism control programs, and those firms that have such programs are unlikely to have all the elements of a good program in place. Placing the occupational health nurse in charge of a comprehensive program will provide needed leadership, responsibility, expertise, and control.

Topic: Workplace Health and Well-being
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
Bacterial chemotaxis control process analysis with SysML

Abstract This paper looks at the bacteria chemotaxis control process utilizing the System Modeling Language (SysML) to leverage well‐defined and proven engineering tools for architecting, analyzing, and refining complex systems. It proposes a new methodology called reverse‐engineering object‐oriented systems engineering method (RE‐OOSEM) that converts descriptive biology research information into descriptive systems engineering information. It utilizes SysML and model‐based systems engineering (MBSE) to capture system architecture from biological system knowledge and inputs them into systems engineering tools. From an engineering point of view, this allows greater insight into how biological systems operate and suggests how much model detail is required to uncover a top‐down system understanding. RE‐OOSEM methodology guides the SysML chemotaxis control capture process. SysML syntax is used instead of biological syntax to facilitate biological chemotaxis control system analysis from an engineered system point of view. The model can act as a scaffolding to help uncover system function, the relationships of system components and processes, and bioinformatic phenotype and genotype correlation. An executable MathWorks Stateflow chemotaxis control process model based on the SysML architectural model is included. The results show the following engineering perspective observations. (1) Several control components are not dedicated but are available and utilized when needed. (2) Individual chemoreceptors act together as a sensor array. (3) Phosphate groups act as a signaling mechanism. (4) Methylation via CH 3 groups of the chemoreceptor results in sensitivity adaptation. (5) Closed‐loop control collaboratively utilizes ligand bonding, phosphorylation, and methylation. (6) Timing relationships of the control subprocesses give insight into the system's architecture.

Topic: Gene Regulatory Network Analysis
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Psychometric Properties of a New Decision-Making Capacity Assessment Tool for People with Substance Use Disorder: The CAT–CAT

Abstract Individuals with substance use disorder (SUD) often present with cognitive impairments, which may impede their ability to make decisions for themselves, including treatment-related decisions. It is therefore important to assess whether individuals with SUD have adequate decision-making capacity. Indeed, there have not been any capacity assessment tools tailored for use with SUD populations that demonstrate adequate psychometric properties or that have the strong ethical foundation that is required of capacity assessment tools. The Compulsory Assessment and Treatment–Capacity Assessment Tool (CAT–CAT) was designed to fill this gap in the literature. Therefore, the aim of this study was to establish the interrater and test–retest reliability, and discriminative validity of the CAT–CAT. The first of this two-part study recruited healthcare professionals in New Zealand and asked them to conduct a capacity assessment on two hypothetical clients. Generally, excellent interrater reliability (ρ = .998 overall) and test–retest reliability (ρ = .996 overall) was found. The CAT–CAT has exhibited reliability that was at least comparable to widely used capacity assessment tools for other pathologies. The second part of this study involved cognitively normal individuals undergoing capacity assessments to investigate the hypothesis that individuals that do not lack capacity will obtain scores significantly higher than 50% in each section of the CAT–CAT. This hypothesis was met with highly significant results. To conclude, preliminary data suggest that the CAT–CAT has excellent reliability and correctly classifies those with capacity.

Topic: Healthcare Decision-Making and Restraints
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Development of an elastic tactile sensor emulating human fingers for tele-presentation systems

We have developed a tactile sensor for tactile tele-presentation systems by focusing on four features of the human finger considered to play an important role in texture perception; the existence of nails and bone, the multilayer structure of soft tissue, the distribution of mechanoreceptors, and the deployment of epidermal ridges. As a result, the developed sensor could detect roughness, softness and friction known to constitute texture perception of humans with precision equivalent to human. In addition, our sensor can be equipped with robot hands as it satisfies the requirements such as size equivalent to human finger, durability to withstand the wearing for repeated use, correspondence for scanning two dimensions.

Topic: Tactile and Sensory Interactions
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
LHD nb1pwr_PortThrough #152024.1 (analyzed)

Neutral beam injector (NBI) power-PortThrough of beam line 1 (BL1). The effective power that actually reaches the plasma after the negative ion-based neutral particle beam emitted from the NBI system passes through BL1.

Topic: GABA and Rice Research
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
VISCOUS DISSIPATION INSTABILITY OF NON-NEWTONIAN FLOW IN A HORIZONTAL POROUS CHANNEL

The onset of thermal convection inside a horizontal porous layer is investigated. An Ostwald-de Waele non-Newtonian fluid is saturating the porous layer. The layer is impermeable with an adiabatic lower boundary and an isothermal upper boundary. A horizontal basic flow with uniform velocity and variable direction is imposed. The viscous dissipation contribution is included into the energy balance equation as internal heat source. A linear stability analysis of the basic state is performed employing the normal mode method. The problem is solved for high values of the Péclet number. The set of ordinary differential equations obtained are solved numerically as an eigenvalue problem by employing the Runge-Kutta method coupled with the shooting method. An accuracy test of the numerical solver is reported. The neutral stability curves are obtained for transverse, oblique, and longitudinal rolls. The threshold conditions of the governing parameters for the onset of thermal convection are reported.

Topic: Nanofluid Flow and Heat Transfer
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Circumscribing Circumscription: A Guide to Relevance and Incompleteness

Intelligent agents in the physical world must work from incomplete information due to partial knowledge and limited resources. An agent copes with these limitations by applying rules of conjecture to make reasonable assumptions about what is known. Circumscription, proposed by McCarthy, is the formalization of a particularly important rule of conjecture likened to Occam's razor. That is, the set of all objects satisfying a certain property is the smallest set of objects that is consistent with what is known. This paper examines closely the properties and the semantics underlying circumscription, considering both its expressive power and limitations. In addition we study circumscription's relationship to several related formalisms, such as negation by failure, the closed world assumption, default reasoning and Planner's THNOT. In the discussion a number of extensions to circumscription are proposed, allowing one to tightly focus its scope of applicability. In addition, several new rules of conjecture are proposed based on the notions of relevance and minimality. Finally a synthesis between the approaches of McCarthy and Konolige is used to extend circumscription, as well as several other rules of conjecture, to account for resource limitations.

Topic: Logic, Reasoning, and Knowledge
Subfield: Artificial Intelligence
Field: Computer Science
Domain: Physical Sciences
Perinatal Mental Health in Community Psychiatry: A Reproductive Psychiatry eConsult Pilot Project

Kennedy proposed his new program in 1963, the state hospitals had already been downsized by more than 54,000 patients, 10% of the total.Community psychiatry was also underway.A few good mental health centers existed prior to the federal program, such as the Prairie View Mental Health Center in Newton, Kansas, which opened in the 1940s.Similarly, the Fountain House Clubhouse in New York had opened in 1948.Thus, community psychiatry predates the federal CMHC program and has continued to thrive since the demise of that program.

Topic: Maternal Mental Health During Pregnancy and Postpartum
Subfield: Public Health, Environmental and Occupational Health
Field: Medicine
Domain: Health Sciences
&lt;p class="HeadingRunIn"&gt;&lt;strong&gt;Six new species, complementary descriptions and new records from the &lt;/strong&gt;&lt;strong&gt;Neotropical Region of the spider genus &lt;em&gt;Dipoena&lt;/em&gt; (Araneae: Theridiidae)&lt;/strong&gt;&lt;/p&gt;

The theridiid genus Dipoena Thorell, 1869 is distributed worldwide. Dipoena are recognized by male with carapace often high, cylindrical, with grooves or depression on dorsum; carapace of female rarely modified, sometimes high. In this paper six new species of Dipoena are described from Brazil, one from the state of Mato Grosso do Sul: Dipoena bonitensis new species, three from São Paulo: Dipoena cidae new species, Dipoena ericae new species and Dipoena santaritadopassaquatrensis new species and two from Paraná: Dipoena guaraquecaba new species and Dipoena fozdoiguacuensis new species, all based on males and females. The males of Dipoena pusilla (Keyserling, 1886); D. peruensis Levi, 1963; D. olivenca Levi, 1963 and D. esra Levi, 1963 and the female of Dipoena niteroi Levi, 1963 are here described and illustrated for the first time. New records from Brazil include Dipoena augara Levi, 1963; D. bryantae Chickering, 1943; D. duodecimpunctata Chickering, 1943; D. isthmia Chickering, 1943; D. kuyuwini Levi, 1963; D. mendoza Levi, 1967; D. puertoricensis Levi, 1963; D. tiro Levi, 1963 and D. trinidensis Levi, 1963; and new records from Bolivia include Dipoena atlantica Chickering, 1943, D. cornuta Chickering, 1943 and D. kuyuwini. New distribution records within Brazil are presented for Dipoena cordiformis Keyserling, 1886; D. hortoni Chickering, 1943; D. ira Levi, 1963; D. militaris Chickering, 1943; D. obscura Keyserling, 1891; D. pumicata (Keyserling, 1886); D. santacatarinae Levi, 1963; D. tingo Levi, 1963 and D. variabilis (Keyserling, 1886).

Topic: Spider Taxonomy and Behavior Studies
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences