jimnoneill/paper-to-field-training huggingface dataset:
&lt;title&gt;Performance analysis of two linear array processing algorithms for obstacle localization&lt;/title&gt;

The performance of a commonly employed linear array of sonar sensors is assessed for point- target localization. Two different methods of combining time-of-flight information from the sensors are described to estimate the range and azimuth of the target: pairwise estimate method and the maximum likelihood estimator. The biases and variances of the methods are investigated and their combined effect is compared to the Cramer-Rao Lower Bound. Simulation studies indicate that in estimating range, both methods perform comparably; in estimating azimuth, maximum likelihood estimate is superior at a cost of extra computation.

Topic: Underwater Acoustics Research
Subfield: Oceanography
Field: Earth and Planetary Sciences
Domain: Physical Sciences
CRANKING THE CHIRAL SOLITON BAG MODEL: QUANTUM CORRECTIONS

The generation of physical states from mean field hedgehogs by cranking is extended to coherent hedgehogs, thus improving the agreement between the cranking and coherent state projection methods, and enabling us to correct simultaneously for translational and rotational fluctuations. These corrections lead to a drastic reduction in the mean nucleon-delta mass which, for the physical values of m π and F π , is lower than, or approximately equal to, the experimental value.

Topic: Quantum, superfluid, helium dynamics
Subfield: Atomic and Molecular Physics, and Optics
Field: Physics and Astronomy
Domain: Physical Sciences
The Shakespeare Society of Philadelphia

Journal Article The Shakespeare Society of Philadelphia Get access Henry L. Savage Henry L. Savage Princeton University Search for other works by this author on: Oxford Academic Google Scholar Shakespeare Quarterly, Volume 3, Issue 4, Autumn 1952, Pages 341–352, https://doi.org/10.2307/2866697 Published: 01 October 1952

Topic: Shakespeare, Adaptation, and Literary Criticism
Subfield: Literature and Literary Theory
Field: Arts and Humanities
Domain: Social Sciences
Identification and isolation of full-length cDNA sequences by sequencing and analysis of expressed sequence tags from guarana (Paullinia cupana)

The current intense production of biological data, generated by sequencing techniques, has created an ever-growing volume of unanalyzed data. We reevaluated data produced by the guarana (Paullinia cupana) transcriptome sequencing project to identify cDNA clones with complete coding sequences (full-length clones) and complete sequences of genes of biotechnological interest, contributing to the knowledge of biological characteristics of this organism. We analyzed 15,490 ESTs of guarana in search of clones with complete coding regions. A total of 12,402 sequences were analyzed using BLAST, and 4697 full-length clones were identified, responsible for the production of 2297 different proteins. Eighty-four clones were identified as full-length for N-methyltransferase and 18 were sequenced in both directions to obtain the complete genome sequence, and confirm the search made in silico for full-length clones. Phylogenetic analyses were made with the complete genome sequences of three clones, which showed only 0.017% dissimilarity; these are phylogenetically close to the caffeine synthase of Theobroma cacao. The search for full-length clones allowed the identification of numerous clones that had the complete coding region, demonstrating this to be an efficient and useful tool in the process of biological data mining. The sequencing of the complete coding region of identified full-length clones corroborated the data from the in silico search, strengthening its efficiency and utility.

Topic: Biofuel production and bioconversion
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Exposure to a more unhealthy diet impacts sleep microstructure during normal sleep and recovery sleep: A randomized trial

Abstract Objective Although intake of specific macronutrients has been associated with sleep parameters, interventional evidence is lacking. Therefore, this randomized trial was conducted to examine how a more unhealthy high‐fat/high‐sugar (HFHS) diet impacts sleep in humans. Methods In a crossover study, 15 healthy young men consumed two isocaloric diets in random order for a week: an HFHS and a low‐fat/low‐sugar diet. Following each diet, in‐lab sleep was recorded using polysomnography during a full night of sleep and during recovery sleep after extended wakefulness. Sleep duration, macrostructure, and microstructure (oscillatory pattern and slow waves) were investigated using machine learning‐based algorithms. Results Sleep duration did not differ across the diets based on actigraphy and the in‐lab polysomnography. Sleep macrostructure was similar after 1 week on each diet. Compared with the low‐fat/low‐sugar diet, consumption of the HFHS diet resulted in reduced delta power, delta to beta ratio, and slow wave amplitude but increased alpha and theta power during deep sleep. During recovery sleep, similar sleep oscillatory changes were observed. Conclusions Short‐term consumption of a more unhealthy diet alters sleep oscillatory features that regulate the restorative properties of sleep. Whether such changes can mediate adverse health outcomes associated with consumption of an unhealthier diet warrants investigation.

Topic: Sleep and Wakefulness Research
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Ubiquitin‐proteasome pathway and nuclear factor‐κB activity in skeletal muscle of mildly weight‐losing cancer patients

Non‐small‐cell lung cancer (NSCLC) is often associated with a systemic inflammatory response and loss of muscle mass (cancer cachexia). In experimental cachexia increased proteolysis through the ubiquitin‐proteasome pathway (UPP) is essential for the loss of muscle mass. Tumor necrosis factor α (TNFα) and the transcriptional regulator nuclear factor κB (NF‐κB) have been implicated in skeletal muscle UPP activation. The aim of this study was to investigate whether the UPP was activated in skeletal muscle of NSCLC patients, and whether systemic inflammation in patients correlated with markers of muscle NF‐κB activity. Vastus lateralis muscle biopsies were collected of 12 NSCLC patients (5% weight loss) and 8 control subjects. Chymotrypsin‐ and caspase‐like proteasome activities were not different, whereas atrogin‐1/MAFbx, but not MuRF‐1, mRNA levels were increased in muscle biopsies of NSCLC patients vs. controls. Although muscle IκBα and TNFα mRNA levels were not different between the two groups, strong correlations between IκBα and both, plasma soluble TNF receptor 55 (R=0.74, p=0.01) and C‐reactive protein (R=0.86, p=0.001) were observed in patients only. Taking the very mild weight loss into account, our results suggest that atrogin‐1 may be an early marker of cancer cachexia. In addition, we show evidence for an association between systemic inflammation and muscle NF‐κB activity in NSCLC patients.

Topic: Nutrition and Health in Aging
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Cryophilic Isotomidae (Collembola) of the Northwestern Rocky Mountains, U. S. A.

Fjellberg, Arne (2010): Cryophilic Isotomidae (Collembola) of the Northwestern Rocky Mountains, U. S. A. Zootaxa 2513: 27-49, DOI: 10.5281/zenodo.196078

Topic: Collembola Taxonomy and Ecology Studies
Subfield: Ecology, Evolution, Behavior and Systematics
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Regional consensus gave birth to the modern public library

In 1982, library experts from 30 Latin American and the Caribbean countries met in Venezuela to discuss the current state and development strategies for the region’s public libraries. The result was the first technical-normative document for public libraries in the region, commonly known as the Caracas Declaration. This issue of Developing Latin America comments on the contents of this document, its influence and importance, and suggests the exercise of invoking and reviewing its principles and objectives to once again analyze the current state and project new development strategies.

Topic: Library Science and Administration
Subfield: Library and Information Sciences
Field: Social Sciences
Domain: Social Sciences
Chi ha bisogno della montagna italiana?

Due to urban and industrial development in the post-war period, the Italian Alps and Apennines have experience an intense phenomenon of depopulation, mainly caused by massive emigration to urban areas. Italian mountain regions, considered for a long time as marginal, neglected areas out of public and political attention, since long have also been affected by different forms of migration that question their representation as ‘places left behind’. At first focusing on the phenomenon of the ‘new mountain people’, and just later on taking into account also the role of foreign migrants in mountain areas, several studies highlighted the fundamental role im-migration flows in transforming Italian mountains, favouring a ‘return to the centre’ of highlands also – and above all – in public and political discourse. This article investigates, also through the analysis of Berceto case, the role – current and potential – of foreign immigrants in this re-thematization in economic, territorial as well as demographic and socio-cultural terms of the marginalized territories of the Alps and Apennines.

Topic: Rural development and sustainability
Subfield: General Agricultural and Biological Sciences
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Research in Practice: Preservice Teachers of the Deaf Action Research With DHH K–12 Learners and Self-Graphing

Abstract: When an instructional strategy lacks evidence of its effectiveness with certain learner groups, educators can conduct action research in their classroom to determine strategy effectiveness. In the present study, seven preservice teachers of the deaf (TODs) implemented self-graphing interventions with deaf/hard of hearing (DHH) learners to change target on- and off-task behaviors. Preservice teachers were master's-level candidates in a university teacher preparation program. DHH learners were 5–16 years old, attended general education classrooms at their local schools or schools for the deaf, and used multiple forms of communication/language. Candidates successfully completed ABAB design studies, and three candidates collected maintenance data after the interventions were withdrawn. They conducted their studies with high interobserver agreement. All DHH learners changed their target behavior when self-graphing was introduced. This study expands self-graphing evidence from high-incidence disability groups to a diverse group of DHH students.

Topic: Hearing Impairment and Communication
Subfield: Developmental and Educational Psychology
Field: Psychology
Domain: Social Sciences
MOESM1 of Full moonlight-induced circadian clock entrainment in Coffea arabica

Additional file 1: Table S0. REPLICATES. Table S1. Genes differentially expressed between Full moon and new Moon at ZT0. Table S2. Genes differentially expressed between Full moon and new Moon at ZT3. Table S3. Genes differentially expressed between Full moon and new Moon at ZT6. Table S4. Genes differentially expressed between Full moon and new Moon at ZT9. Table S5. Genes differentially expressed between Full moon and new Moon at ZT12. Table S6. Genes differentially expressed between Full moon and new Moon at ZT15. Table S7. Genes differentially expressed between Full moon and new Moon at ZT18. Table S8. Genes differentially expressed between Full moon and new Moon at ZT21. Table S9. Genes differentially expressed between Full moon and new Moon at ZT24. Figure S10. Rhythmic genes in common between Coffee and Arabidopsis thaliana. Figure S11. Pairwise phase plots of the core clock genes. Figure S12. Number of genes per phase under new moon and the full moon. Table S13. Correlation matrix between Redox homeostasis genes and LHY. Table S14. Correlation matrix between genes involved in lipids pathways and LHY. Table S14. Primers used for genes studied by qRT-PCR. Figure S16. RT-QPCR of LHY gene during new moon. Figure S17. RT-QPCR time-course of core clock genes, POR1A and GWD1.

Topic: Coffee research and impacts
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Protective Effect of Cast‐Off Skin of <i>Cicadidae Periostracum</i> Water Extract in a Radiation‐Induced Testicular Injury Mice Model

ABSTRACT Radiation therapy has been used to treat cancer; however, the associated DNA damage and adverse effects in the surrounding tissues remain major concerns. In radiation injury, several natural remedies can effectively relieve symptoms with minimal side effects. Cicadidae Periostracum (CP, also called “Sun‐Tae”) is the cast‐off shell of Cryptotympana pustulata Fabricius and has been traditionally used for several pharmacological actions. This study investigated the protective effects of CP water extract (CPE) on irradiated testicular tissue and spermatogenesis. The chemical constituents of CPE were analyzed using a high‐performance liquid chromatography system equipped with a mass detector and were determined to be dimeric N ‐acetyl dopamine derivatives. The testes and epididymal tissues of male C57BL/6 mice orally pretreated with CPE (25 and 50 mg/kg) 24 h and 15 min before radiation exposure (5 Gy) were collected for analysis. CPE pretreatment ameliorated radiation‐induced apoptosis in the testes and inhibited weight loss in the epididymis compared to those of the irradiated group. Treatment with high‐dose CPE prevented the radiation‐induced decrease in the epithelial height of seminiferous tubules. In addition, the morphology, motility, and number of damaged sperm cells following radiation exposure were alleviated by CPE treatment. Furthermore, the dose‐dependent antioxidative activity of CPE was confirmed in 2,2‐diphenyl‐1‐picrylhydrazyl and 2,2′‐azinobis‐(3‐ethylbenzothiazoline‐6‐sulphonic acid) radical scavenging assays, and reactive oxygen species generation by hydrogen peroxide was reduced by CPE treatment in vitro. Our findings suggest that pretreatment with CPE can ameliorate testicular tissue damage and sperm degeneration via the antioxidative properties of CPE in radiation‐injured testis tissue.

Topic: Reproductive Biology and Fertility
Subfield: Public Health, Environmental and Occupational Health
Field: Medicine
Domain: Health Sciences
TOWARDS A NOVEL DESIGN OF CREATIVE SYSTEMS

The topic of the presented investigation is the automation of creative processes via one Synthetic Mata Method (SMM) and few analytic methods considered in the paper and used under SMM control. The prevention of contemporary web threats is discussed at an agent/application level. Advantages and disadvantages of synthetic data mining methods are investigated, and obstacles are revealed to their application in contemporary systems. Novel results for juxtaposing statistical vs. logical data mining methods aiming at possible evolutionary fusions are described. Recommendations are made on how to build more effective applications of classical and/or presented novel (meta) methods: SMM, KALEIDOSCOPE, FUNNEL, PUZZLE, and CONTRADICTION. The usage of ontologies is investigated with the purpose of information transfer by sense. Practical aspects of agent applications, intrusion detection, intrusion prevention, cryptography applications, multiple software and other research results are mentioned aiming to show that intelligent and classical technologies should be carefully combined in one software/hardware complex to achieve the creative goals. It is shown that all the demonstrated advantages may be combined with other known methods and technologies.

Topic: Slime Mold and Myxomycetes Research
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Pharmacological Treatments in Gambling Disorder: A Qualitative Review

Gambling disorder (GD) is a psychiatric condition associated with both social and family costs; DSM-5 currently includes GD among addictive disorders. Despite the high burden of this condition, to date there are no treatment guidelines approved by Food and Drug Administration (FDA). Purpose of this paper is to offer a qualitative overview about the different pharmacologic agents used for the treatment of GD. Our analysis, conducted on a final selection of 75 scientific papers, demonstrates that a variety of pharmaceutical classes have been utilised, with different results. Published data, although limited by brief duration of the studies and small number of enrolled subjects, shows mixed evidence for serotonergic antidepressants, opioid antagonists, and mood stabilizers. Other compounds, such as glutamatergic agents and psychostimulants, deserve further studies.

Topic: Gambling Behavior and Treatments
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
Soluble Urokinase-Type Plasminogen Activator Receptor (suPAR) Is a Biomarker Associated with Left Ventricular Hypertrophy in the Elderly, Specifically in Women

Left ventricular hypertrophy (LVH) may result in the development of heart failure, which is widespread among people of advanced age. The pathophysiology of LVH is complex and its biochemical pathways are not fully understood in this group. Elevated soluble urokinase-type plasminogen activator receptor (suPAR), a biomarker of immune activation, including fibrosis, reflects subclinical organ damage in systematic diseases. The present study assesses the clinical role of suPAR measurement in determination of LVH-associated cardiac disorders in the elderly. The studied population consisted of 238 individuals aged 76–91 years; of these, 139 (58%) were diagnosed with LVH. Serum biomarkers measurement (suPAR, troponin T, NT-proBNP and CRP) and echocardiography were performed in all subjects. The suPAR level was significantly higher in the LVH group (4.01 vs. 3.82 ng/mL, p = 0.033) and correlated with the parameters of cardiac diastolic function. Stepwise logistic regression found suPAR level (OR = 1.55, p = 0.016), BMI (OR = 1.17, p = 0.0003) and hypertension (OR = 2.42, p = 0.046) to be independently associated with LVH in women. In men, the strongest predictors of LVH were hypertension (OR = 7.52, p = 0.014) and BMI (OR = 1.42, p = 0.032). The observations indicate suPAR as a promising marker reflecting LVH, especially in women at advanced age, independent of age-associated cardiac remodeling.

Topic: Cardiovascular Function and Risk Factors
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Reply to the Correspondence on “How Aromatic Are Molecular Nanorings? The Case of a Six‐Porphyrin Nanoring”**

Abstract A recent article by Anderson and co‐workers challenges our conclusions on the aromaticity of the four oxidation states of a butadyine‐linked six‐porphyrin nanoring, based on the experimental 1 H‐NMR data and some recent calculations they have performed using the BLYP35 functional. Here, we show that BLYP35 should be taken with caution and demonstrate that the indirect evidence of a ring current from experimental 1 H‐NMR data is not a definite proof of aromaticity.

Topic: Synthesis and Properties of Aromatic Compounds
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Electrical conduction and breakdown in argon and helium at temperatures from 1500°K to 2500°K

Characteristic current/voltage curves have been obtained for inert gases at high temperature and pressure between coaxial graphite electrodes. Argon and helium of commercial purity have been investigated at pressures from 1 to 2 atmospheres and in the temperature range 1500–2500°K. The geometry chosen was such that the gases and the electrodes were in approximate thermal equilibrium. 400 c/s alternating voltages (up to 500 V peak) were applied to the electrodes, and breakdown occurred at voltages which decreased rapidly as the temperature increased. Below about 2000°K, sharp transitions were observed to either glow-or arc-type discharges. Above this temperature, thermionic emission from the electrodes controlled the form of the characteristic which could be separated into four well defined regions. The initial slopes of the characteristics indicate high effective conductivities, which are believed to be partly associated with the dynamic nature of the characteristics.

Topic: Graphene research and applications
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Knowledge sharing of employees who are envied by their workmates: A resource perspective

Drawing on conservation of resources theory, we examined the effect of workplace envy on the work behaviors and experiences of employees who are envied by others. From the resource perspective, we proposed that ego depletion would mediate the relationship between being envied and knowledge sharing, and that the envied employees' competitive orientation would moderate this mediation. We empirically tested the model with 280 employee–supervisor dyads in China in a two-wave survey. Results show that being envied was negatively related to employees' knowledge sharing, and that the envied employees' ego depletion significantly mediated this negative relationship. Further, envied employees' competitive orientation moderated the indirect mediating effect, such that the negative influence of ego depletion on knowledge sharing was enhanced for those envied employees whose orientation was highly competitive. Our results show the critical role of resource supply and demand on social influence.

Topic: Job Satisfaction and Organizational Behavior
Subfield: Organizational Behavior and Human Resource Management
Field: Business, Management and Accounting
Domain: Social Sciences
CGE-LIF pour cartographie des glycanes : amélioration de méthode et création d'une base de données des N-glycanes

Most biopharmaceuticals are glycoproteins whose inherent properties are highly dependent on their glycosylation patterns. Glycosylation is becoming a crucial quality attribute to control during biotechnological development as it can impact protein activity, stability and half-life in vivo. However the structural elucidation of glycans, which may possess broad structural heterogeneity, represents a substantial analytical challenge. CGE-LIF (Capillary Gel Electrophoresis with Laser-Induced Fluorescence) is a high-throughput analytical method allowing a monitoring of different types of released glycans and their distribution. It provides highly reproducible profiles where all major N-glycans including isomers are quantified. Thanks to the implementation of a new data processing method and to a modification in sample preparation, data processing is faster and migration times are harmonized: a given glycan now always elutes at the same migration time –irrespective of the protein analyzed. The working range of the method has been assessed in terms of precision and accuracy. Ranges were defined in terms of protein quantity to be loaded and maximum peak intensity ensuring linear and robust results. To aid unravelling the glyco-puzzle, a glycan database gathering 64 N-glycans frequently encountered in therapeutic antibodies was implemented. This database enables semi-automated identification of N-glycans based on their migration time calibrated against known migration times of DNA ladder fragments. The improvements set up in CGE-LIF allow quicker and more precise analyses, whether it is for glycosylation monitoring or for N-glycan identification in new proteins in development.

Topic: Glycosylation and Glycoproteins Research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences