jimnoneill/paper-to-field-training huggingface dataset:
Hadrian's Villa and Its Legacy

The great Villa constructed by the Emperor Hadrian near Tivoli between A.D. 118 and the 130s is one of the most original monuments in the history of architecture and art. In this beautiful book, two distinguished architectural historians describe and interpret the Villa as it existed in Roman times and track its extraordinary effect on architects and artists up to the present day. This lavishly illustrated book ... is the most ample and informed work on the villa, its figurative decoration and sculpture collection, and the first study of its reception over the past 500 years.... An essential source of information on one of the glories of Western architecture. -- James S. Ackerman, Times Literary Supplement Authoritative and highly readable, attractively designed with many fine photographs that complement (but do not dominate) the text, it is hard to imagine this study being superseded. -- Architects Journal A comprehensive account of the villa in its heyday and its long afterlife. -- Martin Filler, New York Times Book Review

Topic: Historical and Religious Studies of Rome
Subfield: History
Field: Arts and Humanities
Domain: Social Sciences
Prevention of menstrual attacks of migraine

Although perimenstrual percutaneous estradiol showed benefit during treatment, this was offset by deferred estrogen withdrawal, triggering post-dosing migraine immediately after the gel was stopped. Further work could assess if this could be avoided by extending the duration of treatment with estradiol.

Topic: Migraine and Headache Studies
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Carotenoid cation radicals produced by the interaction of carotenoids with iodine

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarotenoid cation radicals produced by the interaction of carotenoids with iodineRuisong Ding, Janice L. Grant, Robert M. Metzger, and Lowell D. KispertCite this: J. Phys. Chem. 1988, 92, 16, 4600–4606Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August 1988https://pubs.acs.org/doi/10.1021/j100327a010https://doi.org/10.1021/j100327a010research-articleACS PublicationsRequest reuse permissionsArticle Views173Altmetric-Citations39LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts

Topic: Antioxidant Activity and Oxidative Stress
Subfield: Biochemistry
Field: Medicine
Domain: Health Sciences
[Causes and treatment of recurrent varices of the lower limbs].

Recurrence of varicose veins following surgery is a common, complex and costly problem in vascular surgery. The aims of our study were to determine the causes of recurrent varicose vein disease, to compare the preoperative duplex ultrasound findings with surgical findings, and to evaluate the efficacy of our surgical policy. We retrospectively studied 49 limbs operated on for recurrent varicose veins. All patients were monitored 6 weeks and 6 months after surgery and then underwent clinical examination in June 2005. Preoperative duplex ultrasound showed 100% specificity and 97% sensitivity. The patients were operated on for recurrence 152.2 +/- 95.5 months after the primary operation. The incidence of postoperative minor complications was 8.1% and of re-recurrence 10.2%. In 73.5% of patients during surgical re-exploration of the groin we found one or more tributaries of the great saphenous vein/common femoral vein, producing reflux. In 90.1% of cases we also treated incontinent perforator vessels. We recommend surgical re-exploration of the sapheno-femoral venous junction and thorough preoperative study of the perforator vessels in all patients with recurrent varicose veins.

Topic: Diagnosis and Treatment of Venous Diseases
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
LHD TESPEL #154044.1

Tracer-Encapsulated Solid Pellet(TESPEL) is a double-layered impurity pellet, which basically consists of polystyrene polymer (-CH(C6H5)CH2-) as an outer shell and tracer particles as a core. TESPEL can be utilized for various physics-oriented experiments, e.g. impurity injection for the perturbative impurity transport, induction of a cold pulse propagation.

Topic: Biofield Effects and Biophysics
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Pathogenic mutations disrupt stress granules assembly in patients with <i>DDX3X</i> neurodevelopmental disorder

Abstract DDX3X neurodevelopmental disorder (DDX3X-NDD) represents a recently identified genetic syndrome characterized by intellectual disability (ID) and developmental delays, primarily caused by pathogenic variants in the DDX3X gene. The physiological ramifications of these mutations remain largely unexplored. In this study, we reported 21 DDX3X variants from 22 Chinese patients with DDX3X-NDD by whole exome sequencing. We selected five variants for further functional analyses, including two previously reported by our group. Three frameshift variants (c.280_281dup p.R95Efs*127, c.669_670del p.A224Pfs*70, and c.1579del p.H527Ifs*9) resulted in either the loss of DDX3X protein or the production of truncated proteins. Additionally, two missense variants (c.1051C &amp;gt; G p.R351G and c.1501G &amp;gt; A p.A501T) significantly reduced DDX3X protein expression. Notably, variants DDX3X-R95Efs*127 and DDX3X-A224Pfs*70 triggered marked apoptosis induction and failed to form stress granules in HEK293T cells compared to wild-type DDX3X. This defect may stem from their inability to interact with the stress particle marker PABPC1, as evidenced by co-immunoprecipitation assays. Moreover, DDX3X-H527Ifs*9 and DDX3X-R351G variants were found to disrupt the cell cycle, extending the S phase relative to the wild type. Collectively, our findings provide mechanistic insights into the pathogenic consequences of DDX3X-NDD associated mutations, suggesting that the loss-of-function variants of DDX3X lack a context-dependent survival advantage, potentially contributing to the pathology of this syndrome.

Topic: Genetics and Neurodevelopmental Disorders
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Development and Assessment of a Novel Composite Pathologic Risk Stratification for Surgically Resected Human Papillomavirus–Associated Oropharyngeal Cancer

Traditional pathologic risk stratification shows poor survival discrimination for HPV+ OPSCC and classifies many patients with an excellent prognosis as high risk. We derived a novel composite pathologic risk stratification system for HPV+ OPSCC that may be associated with improved survival discrimination.

Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
Phytochemical Investigation of Aristolochias ringens (Vahl.) n-hexane root extract using GC-MS and FTIR

Aristolochia ringens (Vahl.) has been featured in traditional medicinal practices to manage several diseases. This work aims to investigate the phytochemical contents of Aristolochia ringens n-hexane root extract and the functional groups present using Gas Chromatography-Mass Spectrometry (GC-MS) and Fourier Transform Infrared (FTIR) Spectroscopy methods of analysis and also to discuss the major and minor compounds detected with their biological activities. The plant material was extracted by macerating in n-hexane for 72 h. The extract was concentrated to dryness using a rotary evaporator and then screened for secondary metabolites. The phytochemical contents and FTIR were investigated using a GCMS-QP2010SE Shimadzu (Japan) fitted with an MS (Model EI) and an Agilent FTIR spectrophotometer (USA). Sixty-two compounds were detected by the GC-MS and identified using the NIST 11 library. The compounds consist of terpenes (28.97%), steroids and D-modified steroid (17.54%), cannabinoids (23.56%), esters (14.78%), epoxides (3.74%), alkanol, alkynol, and phenolic (3.00%), organosilicone (5.43%), alkanones and nitroalkanone (0.41%), hydrocarbons and chlorohydrocarbon (1.98%), pyrazine ester (0.11%), dioxocin (0.47%), and fatty acid (0.01%). Three cannabinoids are detected, and the most abundant of compounds and cannabinoid is cannabinol. FTIR detected OH-stretch (3327 cm⁻¹), C-H-stretch (2921 cm⁻¹ and 2854 cm⁻¹), C=O stretch (1711 cm⁻¹), C=C (1640 cm⁻¹ and 1462 cm⁻¹), C-O stretch for ether and epoxide (1380 cm⁻¹), and C-O stretch for alkanol (1171 cm⁻¹ and 1074 cm⁻¹). This study revealed the rich phytochemical contents of the n-hexane Aristolochia ringens extract, with their diverse medicinal properties. These results further explained the ethnomedicinal uses of the plant.

Topic: Nephrotoxicity and Medicinal Plants
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Degenerative joint disease: Multiple joint involvement in young and mature dogs

SUMMARY Radiologic, pathologic, and ancillary methods were used to determine the occurrence of degenerative joint disease involving multiple joints of immature and adult dogs. Animals were selected for the development of hip joint dysplasia and chronic degenerative joint disease. Of diseaseprone dogs, 82% (45 of 55 dogs) had radiologic changes, indicative of hip dysplasia, by 1 year of age. At necropsy, more abnormal joints were identified than by radiographic examination. Among 92 dogs between 3 to 11 months of age that had joint abnormalities, 71% had hip joint involvement; 38%, shoulder joint involvement; 22%, stifle joint involvement; and 40% had multiple joint involvement. Polyarthritis was asymptomatic and unexpected. Radiographic examination of older dogs also revealed evidence of degenerative joint disease in many joints. Multiple joint involvement was substantiated at necropsy of young and mature dogs. A similar pattern of polyarticular osteoarthritis was revealed in a survey (computer search) of necropsy reports from medical case records of 100 adult and elderly dogs. Usually, the joint disease was an incidental observation, unrelated to the clinical disease or to the cause of death. The frequent occurrence of degenerative changes in several joints of dogs aged 6 months to 17 years indicated that osteoarthritis may be progressive in these joints and raises the possibility that systemic factors are involved in the disease process.

Topic: Neurological diseases and metabolism
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
COMPARATIVE EVALUATION OF A TWO STROKE COMPRESSED NATURAL GAS MIXER DESIGN USING SIMULATION AND EXPERIMENTAL TECHNIQUES

Compressed Natural Gas (CNG) is a viable alternative fuel that is able to reduce tailpipe emission, most notably in two stroke engines. The excessive by-products of two-stroke engine combustion; normally due to inefficient combustion process is largely attributed to high particulate, carbon monoxide and hydrocarbon constituents. A prototype uniflow-type single-cylinder engine was equipped with a bi-fuel conversion system were used for the work. A dedicated mixer was also developed to meter the gaseous fuel through the engine intake system. It was designed to meet the air and fuel requirement similar to the gasoline counterpart. Modeling of the mixer was made to obtain optimum orifice diameter using three different sizes of 14, 16 and 18mm respectively. Here, flow simulations using a standard (Computational Fluid Dynamics) CFD software were extensively used and the predicted results were subsequently validated using a dedicated a flow test rig. Pressure drop across the venturi is an important parameter as it determines the actual fuel-air ratio in the actual engine. A good agreement of CFD outputs with that of the experimental outputs was recorded. This paper highlights the work, which leads to the use of the dedicated CNG fuelling system in a general-purpose gasoline two-stroke engine.

Topic: Advanced Combustion Engine Technologies
Subfield: Fluid Flow and Transfer Processes
Field: Chemical Engineering
Domain: Physical Sciences
Leadership And Management for The New Era of Public Healthcare in Singapore: A qualitative study of senior healthcare leaders

Background: Singapore's public healthcare system is undergoing significant transformation through the 'Healthier SG' initiative. Effective leadership is crucial to successfully manage this strategic shift and ensure the continued success of the public healthcare model. Methods: A qualitative study was conducted with senior leaders in Singapore's public healthcare sector to identify the key qualities required in future leaders and the necessary environment for nurturing them. In-depth individual interviews (n=46) and online open-ended questionnaires (n=11) were administered, and responses were analysed using thematic analysis. Results: Four key leadership qualities were identified: (i) systems-based thinking to balance competing priorities across the healthcare system, (ii) a long-term perspective with cross-industry experience to understand health within a broader sociological context, (iii) personal integrity, honesty, and authenticity aligned with public service values, and (iv) strong communication and collaboration skills to foster a shared vision. The study also highlighted four essential environmental factors to cultivate future leaders: (i) a healthcare system that embraces learning, innovation, and failure as part of growth, (ii) opportunities for cross-functional rotation and networking, (iii) a mature talent management system with robust succession planning and senior leaders as role models, and (iv) a focus on people management and talent potential over seniority in leadership selection. Conclusion: As Singapore transforms its healthcare system with a focus on population health, developing capable leaders is essential for achieving long-term strategic goals. This study provides insights for policymakers, senior healthcare leaders, and HR planners to identify and foster talent, creating an environment where future healthcare leaders can thrive.

Topic: Human Resource and Talent Management
Subfield: Organizational Behavior and Human Resource Management
Field: Business, Management and Accounting
Domain: Social Sciences
BENTUK PENYAJIAN TARI RADDAT APE NANG DITUMBOK DI KABUPATEN SAMBAS KALIMANTAN BARAT

This study aims to describe the form presentation of the Raddat Ape Nang Ditumbok Dance in Sambas Regency, West Kalimantan. The problem of this research is related to the elements of the presentation form of the Raddat Ape Nang Ditumbok Dance. This research uses qualitative approach. The authors used descriptive method to analyse the cheography of the Raddat Ape Nang Ditumbok Dance. The authors involved two informants in the process of interview. The authors also used observation dan document analysis in this study. Based on the interview, observation and document analysis, the authors concluded that the Raddat Ape Nang Ditumbok dance consists of 6 to 12 female players. This dance comprises 5 movements, namely “menumbuk padi”, “menampi padi”, “timang burung”, “nyiur melambai”, and “sedih bahagia”. The floor pattern in this dance uses horizontal, triangular, and zig-zag floor patterns. The musical instruments used in the the Raddat Ape Nang Ditumbok Dance are tambourines, long drums (kedumbak), tahar, and rumba. The dance is accompanied with song. The dancers use realistic make-up, the clothes used are brackets, tapeh sarong, bun, lotus, and head accessories such as rocking flowers and earrings. The venue used must be a proscenium stage and an open field.

Topic: Cultural and Artistic Studies
Subfield: Cultural Studies
Field: Social Sciences
Domain: Social Sciences
Additional file 3 of Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles

Additional file 3: Tables S1. Summary of the Wilcoxon rank sum test for the first three principal comments scores of PCA at both weeks 8 and 26.

Topic: Gut microbiota and health
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Inseets Attacking <i>Cordia macrostdchya</i> (Jacq.) Roem. and Schult in the West Indies

This is the second of a series of papers dealing with the life-histories of a number of insects attacking the black sage, Cordia macrostachya , in the West Indies, where search is being made for suitable species to use in an attempt at the biological control of the weed in Mauritius (Simmonds 1949). Schematiza , like Physonota alutacea , is a leaf-eating beetle, sometimes occurring in relatively large numbers on Cordia . It is very heavily parasitized in Trinidad, and as it appeared to be very suitable for introduction into Mauritius it was investigated in detail, both in the field and in the laboratory.

Topic: Biological Control of Invasive Species
Subfield: Insect Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Lipid Effect on the Progress of Artificial Carious Lesions in Dental Enamel

The aim of the study was to examine the effect of enamel lipids on the rate of progress of artificial carious lesions in dental enamel. Lipids were extracted from cut halves of human tooth crowns. Artificial carious lesions were formed in both lipid-extracted and control halves in a lactate-diphosphonate system over 2, 1, 14 and 21 days at 37 °C. A twofold increase in lesion formation rate occurred in the lipid-extracted teeth compared to the normal teeth. The lipid component of enamel apparently acts as a diffusion barrier during the enamel caries process, and inhibits demineralization.

Topic: Oral microbiology and periodontitis research
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Atmospheric dispersion in oblique imaging from an airborne platform

In a stand-off imaging scenario from a high-altitude airborne platform, the camera line-of-sight (LOS) passes through atmosphere layers of variable density at an oblique angle. Dispersion blur arises because of wavelength-dependent refraction in the atmosphere. In visible-and-near-infrared (VNIR) spectral band the atmospheric dispersion is significant and has some effect onto resolution performance in LOS elevation dimension. Historically the atmospheric refraction and dispersion issues were studied and analyzed in astronomy, considering an infinitely distant celestial body imaged by a ground-based telescope. The calculation involves an atmosphere properties model as well as an expression for air refractive index as function of pressure, temperature and humidity. However, a straightforward application of the star–to-ground telescope refraction formulae to the ground target–toairborne camera case leads to incorrect results. In the latter case boundary conditions for light ray refraction are different, since the ground target-to-camera distance is finite rather than infinite. There are dispersion-related ray angle differences both at departure of light from the target and on arrival to the camera. Only the latter part of the overall atmospheric dispersion is perceived at the camera and causes image blur. An iterative method of the camera-perceived dispersion calculation is presented. Parametric study results illustrate the dispersion dependence on camera altitude and LOS zenith angle. The model results are validated by comparison to vertical-to-horizontal sharpness ratio statistics calculated from images taken by Condor2 cameras at various ranges. The dispersion-related NIIRS grade loss is relatively small, and in most practical cases no optical compensation of the atmospheric dispersion is necessary.

Topic: Optical measurement and interference techniques
Subfield: Computer Vision and Pattern Recognition
Field: Computer Science
Domain: Physical Sciences
Rutin and quercetin content in the forage of common buckwheat as affected by maturity and conservation method

Abstract The content of rutin and quercetin was examined in fresh, hayed and ensiled forage of common buckwheat. The treatments were two varieties of buckwheat, ‘Bamby’ and ‘Lileja’, and two ripening stages of harvest, first green and first brown achenes. In the silage, produced with experimental mini‐silos, additional treatments were the wilting of the forage (at 35% dry matter) and the addition of Lactobacillus plantarum as inoculum. The concentration of rutin and quercetin decreased between ripening stages. Flavonoid content was different among varieties, ‘Lileja’ had the highest rutin concentration (about 20 g kg −1 ), while ‘Bamby’ had the highest quercetin concentration (about 0.2 g kg −1 ). Rutin and quercetin yield reached about 70 kg ha −1 and 500 g ha −1 , respectively. The haymaking process reduced the rutin and quercetin concentration in the forage, however, the extent of reduction was higher at the green (−43% for rutin and −55% for quercetin) than at the brown achenes stage (−13% rutin and −26% quercetin). The ensiling process, with the associated bacterial activities, led to the transformation of rutin into quercetin. The decrease of rutin in the silage, compared to fresh forage, ranged between −84 and −99%, while in contrast, the quercetin concentration increased by about 140–200 times. However, the loss of total rutin plus quercetin during ensiling was limited (approximately 5%). Forage wilting negatively affected rutin transformation in quercetin, while bacterial inoculum improved it. These results highlight that the forage of buckwheat could be considered like a dietary supplement rich of flavonoids, with the potential to be used as functional feed * .

Topic: Seed and Plant Biochemistry
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
[Non-invasive cerebral oximetry monitoring in percutaneous cardiac valvular implantations: two cases report].

Cerebral oximetry non-invasive technology is based on cerebral tissue oxygen saturation (StcO2) measure in microcirculation, through near-infrared spectroscopy (NIRS)). As a result, cerebral oximetry (StcO2) is a mixed oxygen saturation parameter between de-oxide and oxide hemoglobin witch estimates a value between arterial (SaO2) and jugular venous saturation (SvjO2) under physiologic conditions. Complementary to the arterial oxygen saturation measured by pulse oximetry, cerebral tissue oxygen saturation reflects regional cerebral metabolism and the balance of local cerebral oxygen supply and demand. In this article, the authors report two clinical cases, the first case of a 79 year old man, submitted to percutaneous aortic valve bioprothesis femoral implantation, complicated by a stroke event, expressed by cerebral hypoxia in StcO2 monitorization on the left hemisphere and clinical motor deficit evidence, and the second one a 73 year old man, ASA III, submitted to percutaneous aortic valve bioprosthesis subclavian implantation procedure, where no complications were decribed and haemodymic and StcO2 stability was noticed.Given the clinical evidence on the reported cases, StcO2 monitorization revealed to be a relevant and usefull tool, in order to identify cerebral tissue hypoxia in the first case, as well as reflecting the adequate balance of local cerebral oxygen supply and demand, in the later.

Topic: Traumatic Brain Injury and Neurovascular Disturbances
Subfield: Neurology
Field: Medicine
Domain: Health Sciences