jimnoneill/paper-to-field-training huggingface dataset:
Leading the way in clinical effectiveness

The Bradley Report heralded a fundamental change in the operation of the ambulance services and one of its main objectives was to improve clinical leadership. Here, we learn about the man charged with delivering these improvements and the initiatives that he has spearheaded in the East Midlands Ambulance Service and beyond.

Topic: Nursing Roles and Practices
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
Rb756 Gar-2(Ok520)Iii | 2010-07-22T11:24:00+01:00

This experiment is part of the <em>C.elegans behavioural database</em>. For more information and the complete collection of experiments visit http://movement.openworm.org <b>preview link</b> : https://www.youtube.com/watch?v=cidLyjFhYG4 <b>strain</b> : RB756 <b>timestamp</b> : 2010-07-22T11:24:00+01:00 <b>gene</b> : gar-2 <b>chromosome</b> : III <b>allele</b> : ok520 <b>strain_description</b> : gar-2(ok520)III <b>sex</b> : hermaphrodite <b>stage</b> : adult <b>ventral_side</b> : anticlockwise <b>media</b> : NGM agar low peptone <b>arena</b> : <b>style</b> : petri <b>size</b> : 35 <b>orientation</b> : away <b>food</b> : OP50 <b>habituation</b> : 30m wait <b>who</b> : Laura Grundy <b>protocol</b> : Method in E. Yemini et al. doi:10.1038/nmeth.2560. Worm transferred to arena 30 minutes before recording starts. <b>lab</b> : <b>name</b> : William R Schafer <b>location</b> : MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH, UK <b>software</b> : <b>name</b> : tierpsy (https://github.com/ver228/tierpsy-tracker) <b>version</b> : cbfc23eb4f1ac2f29be75ade7a937eed58a5b219 <b>featureID</b> : @OMG <b>base_name</b> : gar-2 (ok250)III on food R_2010_07_22__11_24___3___3 <b>total time (s)</b> : 898.102 <b>frames per second</b> : 24.0385 <b>video micrometers per pixel</b> : 4.53292 <b>number of segmented skeletons</b> : 21542

Topic: Solid-state spectroscopy and crystallography
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Preliminary study on the prevalence of Varroa sp in honeybee colonies in the village of Mondon (Burkina Faso)

In Burkina Faso, beekeeping is practised throughout the country. It has many potentialities, but it faced many constraints. Sanitary constraints are less investigated and need to be elucidate for a better management of bee colonies and improvement of beekeeping. A descriptive study was conducted in Cascades region to assess the prevalence and the density of Varroa mite infestation. The method of sugar shake on adult bees was used. The overall prevalence found was 91.7% [95% CI: 83.8% - 99.5%] and the density varied from 0.3 mite/100 bees to 12.3 mites/100 bees. These results show that the Varroa mite is widespread in bee colonies and its monitoring should be considered for bee health management, which is essential for sustainable beekeeping. Advanced research is needed in a large sample area to further investigate the epidemiological aspects and the potential impact of the mite on honeybee production.

Topic: Insect and Pesticide Research
Subfield: Insect Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Disparities of Care in Post-Concussive Pediatric Patients

The objective of this study was to examine the association between insurance status and prevalence of follow up care at a tertiary referral center compared to the emergency department.Concussions are extremely common in today's society, affecting patients of all demographic backgrounds. There is concern that public insurance status may affect follow up care at tertiary treatments centers compared to children with private insurance, as evidenced by Copley et al. who documented insurance disparities between children presenting to a sports medicine clinic with orthopedic injuries verses concussion.We compared insurance status of patients presenting to our pediatric concussion clinic to the insurance status of patients diagnosed with concussion at the emergency department of our tertiary hospital. From 2018 to 2019, 725 patients received an ICD-10 diagnosis code for concussion in our clinic. Patients were excluded if insurance status was not available for the clinic visit (4), or if they were lost to follow up (380). ICD-10 codes for concussion during the same period were recorded from the COA emergency department (ED). The insurance status was then recorded for each patient.Of the 345 patients included from the COA concussion clinic, 253 (73%) patients had private insurance while only 92 (27%) had public insurance. In comparison, of the 1,160 patients diagnosed with concussion in the COA ED, 642 (55%) patients had private insurance, 478 (41%) had public insurance, 37 (3.1%) were self-pay, and 3 (0.3%) were listed as "other."There is a significant difference in the insurance status of patients with concussion that present to the COA ED when compared to those presenting to concussion clinic. As a result, children with public insurance may have prolonged recovery and more significant symptoms burden compared to children with private insurance.

Topic: Hip and Femur Fractures
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Consumer Acceptance toward Functional Foods: A Scoping Review

Chronic diseases (e.g., heart disease, cancer, diabetes) are of major public concern. Such chronic diseases are often caused by a dietary pattern characterized as relatively high in fat, refined sugar, salt, and cholesterol. Societal interest in consuming healthy foods and the demand for healthy food products have increased significantly. As a result, functional foods have gained significant research attention in the food health and technology innovations field. To date, many studies have investigated the factors that may predict consumer acceptance of functional foods, and a wide range of influential factors have been reported. However, studies conducted in different contexts pose challenges to gaining a clear understanding of the factors influencing consumer acceptance. Therefore, the purpose of our scoping review was to synthesize the possible determinants of consumer acceptance toward functional foods and provide a resource that describes global trends regarding consumers’ functional foods behavior. We identified 75 articles published with varying populations around the globe that empirically investigated consumers’ acceptance of functional foods. We identified and categorized a wide range of determinants related to consumer acceptance of different types of functional foods. The five categories of determinants were product characteristics, socio-demographic characteristics, psychological characteristics, behavioral characteristics, and physical characteristics. Each of the determinants were more fully described by sub-determinants in our scoping review. These determinants should be considered and used by leaders and scientists in product development to aid decision making and, ultimately, the successful launch of novel functional foods.

Topic: Consumer Attitudes and Food Labeling
Subfield: Public Health, Environmental and Occupational Health
Field: Medicine
Domain: Health Sciences
Multivariate analysis of the association of acid and duodeno-gastro-oesophageal reflux exposure with the presence of oesophagitis, the severity of oesophagitis and Barrett&amp;apos;s oesophagus.&amp;quot; Gut 57(8

bilitec monitoring, multivariate analysis the Corresponding Author has the right to grant on behalf of all authors and does grant on behalf of all authors, an exclusive licence (or non exclusive for government employees) on a worldwide basis to the BMJ Publishing Group Ltd and its Licensees to permit this article (if accepted) to be published in GUT and any other BMJPGL products to exploit all subsidiary rights, as set out in our licence

Topic: Gastroesophageal reflux and treatments
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Alexander disease

Alexander disease has always been considered a classic leukodystrophy (the term literally meaning abnormal white matter nutrition, but usually used more broadly to indicate any hereditary or metabolic white matter abnormality). Although rare (the true incidence is not yet known), the disease is always included in the differential diagnosis when encountering an infant with macrocephaly, delayed development, and an abnormal neuroimaging study primarily affecting the frontal lobes. Confirmation of the diagnosis previously required brain biopsy or autopsy, and demonstration of protein aggregates known as Rosenthal fibers within the cytoplasm of astrocytes. MRI criteria for diagnosis, as refined by van der Knaap et al.,1 noted additional features besides frontal white matter defects (a periventricular rim with high signal on T1-weighted images and low signal on T2-weighted images, abnormalities of the basal ganglia and thalami, brainstem abnormalities, and contrast enhancement of particular gray and white matter structures) and are now highly reliable benchmarks for clinical practice. The realization that mutations in the astrocyte intermediate filament GFAP are responsible for nearly all cases transformed the clinical approach for the most common, infantile, form. …

Topic: RNA regulation and disease
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
A new approach to develop cost-effective lignocellulosic bioethanol production

2\(^n\)\(^d\)-generation bioethanol can be produced from cellulose fraction present in lignocellulosic biomass and has become a significant research focus due to its potential for replacing fossil fuels and decreasing greenhouse gases emissions. In order to produce 2\(^n\)\(^d\)-generation bioethanol, biomass processing is required in order to access cellulose within lignocellulose and convert it into glucose. However, an efficient cost-effective and environmental-friendly process has not been achieved. The aim of this work was to produce glucose from purified cellulose from \(Miscanthus\) \(x\) \(giganteus\), an energy crop. The lignocellulosic biomass was selectively fractionated into its main components, hemicellulose, lignin and cellulose, after extractions using ‘green’ processes in a biorefinery approach. Hydrolysis of the cellulose-enriched fibres into glucose was evaluated using subcritical water (SBW) in a batch reactor at temperatures from 190-320oC, residence times from 0-54min and biomass loading from 0.5-6.4% (w/v). The process used for cellulose purification had significant effect on glucose production by SBW, and higher glucose yields were achieved at higher temperatures and shorter residence times. Glucose was used for bioethanol production. Although the formation of inhibitors during SBW hydrolysis could not be prevented, fermentation could be performed in the presence of these compounds at some conditions, with high ethanol yields.

Topic: Biofuel production and bioconversion
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Respiratory distress syndrome: perinatal prediction of one year development outcome.

A number of perinatal variables were entered into multivariate regression analyses to determine which variables predicted the one-year Bayley Mental and Motor scores of 46 infants surviving the respiratory distress syndrome. Significant predictors were gestational age, 5 minute Apgar scores, obstetric complications, duration of IPPV and intensive care. Although gestational age was the strongest single predictor of developmental outcome, its predictive power was enhanced by the addition of the other significant perinatal variables. A greater number of the RDS infants received low motor scores as opposed to low mental scores, suggesting that intervention efforts with this group might focus on the development of early sensorimotor skills.

Topic: Infant Development and Preterm Care
Subfield: Pediatrics, Perinatology and Child Health
Field: Medicine
Domain: Health Sciences
Algorithmic information theory

This article is a brief guide to the field of algorithmic information theory (AIT), its underlying philosophy, and the most important concepts. AIT arises by mixing information theory and computation theory to obtain an objective and absolute notion of information in an individual object, and in so doing gives rise to an objective and robust notion of randomness of individual objects. This is in contrast to classical information theory that is based on random variables and communication, and has no bearing on information and randomness of individual objects. After a brief overview, the major subfields, applications, history, and a map of the field are presented.

Topic: Computability, Logic, AI Algorithms
Subfield: Computational Theory and Mathematics
Field: Computer Science
Domain: Physical Sciences
Schedulability analysis for dual-armed cluster tools with mixed-processing of multi-variety wafers

Wafer fabrication tends to small batch, and single wafer processing is effective in cluster tools. With the decrease of processes, redundant processing modules are adopted to improve the utilization of cluster tools. The scheduling of mixed-processing of multi-variety wafers should be developed for dual-armed cluster tools. Based on resource oriented Petri net model, we analyze the process by the traditional swap strategy, then wafer processing cycle time and robot cycle time are obtained. A theorem of the schedulability is achieved by analyzing the processing parameters of multi-variety wafers. The schedule is obtained by a scheduling determining programming. Finally, illustrative examples are presented to show the usage of the programming.

Topic: Scheduling and Optimization Algorithms
Subfield: Industrial and Manufacturing Engineering
Field: Engineering
Domain: Physical Sciences
Compressive sensing method for EUV source optimization using different bases

An EUV source optimization technique using compressive sensing is introduced in this paper. The pixelated source pattern is sparsely represented in a set of certain basis functions. Blue noise sampling method is used to select sampling points around the margins of the target layout for imaging fidelity evaluation. Based on the compressive sensing theory, the EUV SO is formulated as an l1-norm inverse reconstruction problem and solved by the linearized Bregman algorithm. Different types of sparse bases are also experimented in this paper to investigate their impact on the SO results. These bases include the 2D-DCT basis, spatial basis, Zernike basis, and Haar wavelet basis. Simulations show that ℓthe Haar wavelet basis results in the best imaging fidelity among the four types of bases.

Topic: Advancements in Photolithography Techniques
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
The MEMOWAVE project: A phase I/II clinical trial targeting treatment of mild cognitive impairment through sound stimulation during slow‐wave sleep

Abstract Background Mild Cognitive Impairment (MCI) is a highly prevalent syndrome especially among the elderly, but its treatment remains challenging. The MEMOWAVE project is a phase I/II randomized, double blind and cross‐over clinical trial. The first objective is to validate the safety and tolerance of a device consisting of a small microphone, also equipped with electroencephalographic electrodes, inserted in the external ear canals. The device produces pink noises during slow‐wave sleep based on real‐time EEG acquisition. The second objective is to investigate the effectiveness of this device in amplifying cerebral slow waves during sleep through sound emission. The third objective is to study the effect of this stimulation on memory consolidation, attention, executive functions, insight, creativity and mood in patients with MCI. Indeed, there is converging evidence that deep slow‐wave sleep plays a major role in these aspects. This process has already shown improvements in memory performance in healthy subjects and during normal aging. Method Twenty‐four patients between 40 and 85 years of age will spend three nights in a Center for sleep disorders. Their cognitive functions, insight, creativity abilities and mood will be tested before and after a night of slow wave stimulation or placebo (device in place without stimulation), in a randomized and crossover fashion. Result We expect that this device will represent a simple therapeutic approach, easily tolerable by the patient, and able, if successful, of being offered quickly to a larger population of patients with MCI. Conclusion We are proposing a new innovative methodology for the treatment of MCI which we are going to test for safety and efficacy.

Topic: EEG and Brain-Computer Interfaces
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Chinese Poplar Propolis Inhibits MDA-MB-231 Cell Proliferation in an Inflammatory Microenvironment by Targeting Enzymes of the Glycolytic Pathway

Propolis is rich in flavonoids and has excellent antitumor activity. However, little is known about the potential effects of propolis on glycolysis in tumor cells. Here, the antitumor effects of propolis against human breast cancer MDA-MB-231 cells in an inflammatory microenvironment stimulated with lipopolysaccharide (LPS) were investigated by assessing the key enzymes of glycolysis. Propolis treatment obviously inhibited MDA-MB-231 cell proliferation, migration and invasion, clone forming, and angiogenesis. Proinflammatory mediators, including tumor necrosis factor-alpha (TNF-α), interleukin (IL)-1β, and IL-6, as well as NLRP3 inflammasomes, were decreased following propolis treatment when compared with the LPS group. Moreover, propolis treatment significantly downregulated the levels of key enzymes of glycolysis–hexokinase 2 (HK2), phosphofructokinase (PFK), pyruvate kinase muscle isozyme M2 (PKM2), and lactate dehydrogenase A (LDHA) in MDA-MB-231 cells stimulated with LPS. After treatment with 2-deoxy-D-glucose (2-DG), an inhibitor of glycolysis, the inhibitory effect of propolis on migration was not significant when compared with the LPS group. In addition, propolis increased reactive oxygen species (ROS) levels and decreased mitochondrial membrane potential. Taken together, these results indicated that propolis targeted key enzymes of glycolysis to suppress the proliferation of MDA-MB-231 cells in an inflammatory microenvironment. These studies provide a molecular basis for propolis as a natural anticancer agent against breast cancer.

Topic: Bee Products Chemical Analysis
Subfield: Insect Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
The experimental investigation of the circulation of the bilirubin in the intestinal canal

Dr. Sakakibara has positively proved by the streams-examination of the van den Bergh and Lepehne's hypothesis, that the bilirubin which shows only the so called van den Bergh's indirect reaction is primarily produced in the all reticuloendothelial system, and that, by the function of the hepatic cells, it is converted into the bilirubin which shows indirect and direct reaction, and that is excreted into the bile duct.But the consequence of the Bergh's reaction of the bilirubin in the intestines does not seem to have been determined. Regarding this problem, I have performed several experiments and reached the following results.The bilirubin-Index, the direct reaction of the Bergh's reaction in the intestines is not influenced by the pancreas juice, ferments, bakteria and white blood corpscles; While the bilirubin is taken up by the small intestinal wall, it is influenced by the vital force of the epithelial cells, and then only the indirect bilirubin is absorved into the lymph and blood vessels, so the epithelial cells of the small intestine give a very important influence to the bilirubin-Index in the small intestince.

Topic: Neonatal Health and Biochemistry
Subfield: Pediatrics, Perinatology and Child Health
Field: Medicine
Domain: Health Sciences
Supplementary Tables 1-2 from Autophagy Is Activated by TGF-β and Potentiates TGF-β–Mediated Growth Inhibition in Human Hepatocellular Carcinoma Cells

Supplementary Tables 1-2 from Autophagy Is Activated by TGF-β and Potentiates TGF-β–Mediated Growth Inhibition in Human Hepatocellular Carcinoma Cells

Topic: Metabolism, Diabetes, and Cancer
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
The occurrence of copper in Shasta County, California; Geology of the copper districts near Montpelier, Bear Lake County Idaho; The copper deposits of South Mountain in southern Pennsylvania; Survey publications of copper

Shasta County lies just south of the northernmost tier,of counties in California, about midway between the eastern and western boundaries of the State.The Shasta County copper region is a somewhat ill-defined area lying near the middle of the western half of the county, 80 to 100 miles east of the Pacific and at about the latitude of New York City.It is included within meridians 122° and 122° 33' west longitude and parallels 40° 37' and 40° 50' north latitude.Next to.the Lake Superior district of Michigan it is areally the largest copper region in the United States that can be regarded as a geologic unit.As commonly described, it is a narrow curved belt, convex toward the north, popularly known as the "copper crescent."From tip to tip this bow measures about 25 miles in a direction but little north of east, but the length measured along the curve is nearly 35 miles.In reality this " crescent" or "belt" is simply the locus of a number of deposits or groups of deposits, separated by stretches in which important deposits of copper are not known and throughout most of which such deposits probably do not exist.It is more exact, therefore, to regard the belt, so far as now developed, as a number of detached camps or districts which, more by chance than because of o This paper contains a preliminary statement of the salient features of the Shasta County copper region aad of some of the general conclusions already reached, and has been presented, in response to a request by the Geological Survey, in advance of a detailed geologic report now being prepared.It should be borne in mind that although the conclusions herein expressed are for the most part well established by evidence to be presented later, they are not necessarily final and are subject to any modification that may be found necessary as the result of additional study now in progress. 71

Topic: Geological and Geochemical Analysis
Subfield: Geophysics
Field: Earth and Planetary Sciences
Domain: Physical Sciences