jimnoneill/paper-to-field-training huggingface dataset:
[The application scenarios study on the intervention of cognitive decline in elderly population using metaverse technology].

China is facing the peak of an ageing population, and there is an increase in demand for intelligent healthcare services for the elderly. The metaverse, as a new internet social communication space, has shown infinite potential for application. This paper focuses on the application of the metaverse in medicine in the intervention of cognitive decline in the elderly population. The problems in assessment and intervention of cognitive decline in the elderly group were analyzed. The basic data required to construct the metaverse in medicine was introduced. Moreover, it is demonstrated that the elderly users can conduct self-monitoring, experience immersive self-healing and health-care through the metaverse in medicine technology. Furthermore, we proposed that it is feasible that the metaverse in medicine has obvious advantages in prediction and diagnosis, prevention and rehabilitation, as well as assisting patients with cognitive decline. Risks for its application were pointed out as well. The metaverse in medicine technology solves the problem of non-face-to-face social communication for elderly users, which may help to reconstruct the social medical system and service mode for the elderly population.

Topic: Medical Research and Treatments
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
IBM POWER6 accelerators: VMX and DFU

The IBM POWER6™ microprocessor core includes two accelerators for increasing performance of specific workloads. The vector multimedia extension (VMX) provides a vector acceleration of graphic and scientific workloads. It provides single instructions that work on multiple data elements. The instructions separate a 128-bit vector into different components that are operated on concurrently. The decimal floating-point unit (DFU) provides acceleration of commercial workloads, more specifically, financial transactions. It provides a new number system that performs implicit rounding to decimal radix points, a feature essential to monetary transactions. The IBM POWER™ processor instruction set is substantially expanded with the addition of these two accelerators. The VMX architecture contains 176 instructions, while the DFU architecture adds 54 instructions to the base architecture. The IEEE 754R Binary Floating-Point Arithmetic Standard defines decimal floating-point formats, and the POWER6 processor—on which a substantial amount of area has been devoted to increasing performance of both scientific and commercial workloads—is the first commercial hardware implementation of this format.

Topic: Numerical Methods and Algorithms
Subfield: Computational Theory and Mathematics
Field: Computer Science
Domain: Physical Sciences
CCDC 914393: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Robotic Harvesting System for Eggplants

The harvesting operation for eggplants is complicated and accounts for a little less than 40% of the total number of working hours. For automating the harvesting operation, an intelligent robot that can emulate the judgment of human labor is necessary. This study was conducted with a view to developing a robotic harvesting system that performs recognition, approach, and picking tasks. In order to accomplish these tasks, 3 essential components were developed. First, a machine vision algorithm combining a color segment operation and a vertical dividing operation was developed. The algorithm could detect the fruit even under different light conditions. Next, a visual feedback fuzzy control model to actuate a manipulator was designed. The control model enabled the manipulator end to approach the fruit from a distance of 300 mm. Furthermore, an end-effector composed of a fruit-grasping mechanism, a size-judging mechanism, and a peduncle-cutting mechanism was developed. It produced enough force for grasping the fruit and cutting the tough peduncle. Finally, the 3 essential components were functionally combined, and a basic harvesting experiment was conducted in the laboratory to evaluate the performance of the system. The system showed a successful harvesting rate of 62.5%, although the end-effector cut the peduncle at a slightly higher position from the fruit base. The execution time for harvesting of an eggplant was 64.1 s.

Topic: Smart Agriculture and AI
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Evidence for the Innateness of Deontic Reasoning

Abstract: When reasoning about deontic rules (what one may, should, or should not do in a given set of circumstances), reasoners adopt a violation‐detection strategy, a strategy they do not adopt when reasoning about indicative rules (descriptions of purported state of affairs). I argue that this indicative‐deontic distinction constitutes a primitive in the cognitive architecture. To support this claim, I show that this distinction emerges early in development, is observed regardless of the cultural background of the reasoner, and can be selectively disrupted at the neurological level. I also argue that this distinction emerged as a result of selective pressure favouring the evolution of reasoning strategies that determine survival within dominance hierarchies.

Topic: Child and Animal Learning Development
Subfield: Developmental and Educational Psychology
Field: Psychology
Domain: Social Sciences
Motion Correction via Locally Linear Embedding for Helical Photon-counting CT

X-ray photon-counting detector (PCD) offers low noise, high resolution, and spectral characterization, representing a next generation of CT and enabling new biomedical applications. It is well known that involuntary patient motion may induce image artifacts with conventional CT scanning, and this problem becomes more serious with PCD due to its high detector pitch and extended scan time. Furthermore, PCD often comes with a substantial number of bad pixels, making analytic image reconstruction challenging and ruling out state-of-the-art motion correction methods that are based on analytical reconstruction. In this paper, we extend our previous locally linear embedding (LLE) cone-beam motion correction method to the helical scanning geometry, which is especially desirable given the high cost of large-area PCD. In addition to our adaption of LLE-based parametric searching to helical cone-beam photon-counting CT geometry, we introduce an unreliable-volume mask to improve the motion estimation accuracy and perform incremental updating on gradually refined sampling grids for optimization of both accuracy and efficiency. Our numerical results demonstrate that our method reduces the estimation errors near the two longitudinal ends of the reconstructed volume and overall image quality. The experimental results on clinical photon-counting scans of the patient extremities show significant resolution improvement after motion correction using our method, which reveals subtle fine structures previously hidden under motion blurring and artifacts.

Topic: Advanced X-ray and CT Imaging
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Dynamic web server construction on the intranet using a change management framework

As organizations increasingly emphasize effective collaborative working through networked systems, the World Wide Web (WWW) server and associated intranet technologies are gaining wider acceptance as a new enterprisewide information systems paradigm. In an intranet collaborative working environment, data used in the web server are usually modified more frequently than are those used in a traditional Internet web server. Thus, to support synchronous collaboration without causing any inconsistency among multiple concurrent users, the intranet web server must provide users with synchronized and consistent views of shared data. However, current web technologies have limitations in supporting this, largely because the existing Hypertext Transfer Protocol (HTTP) is unidirectional and does not allow web servers to send messages to their web browsers without first receiving requests from them. This paper proposes a web-based change management framework that can overcome such limitations and support synchronous collaboration in an intranet computing environment. The web-based change management framework facilitates management of dependency relationships between shared data in the web server and dependent user views in the client web browser and allows the web server to actively propagate changing details of the shared objects to all users referencing them. On the basis of the change management framework, we propose a dynamic web server that can support synchronous collaboration in various intranet-based collaborative systems including concurrent engineering design systems and electronic approval systems. The prototype system of the dynamic web server is developed on a commercial Object-oriented Database Management System (ODBMS) called OBJECTSTORE using the C++ programming language. Copyright © 1999 John Wiley & Sons, Ltd.

Topic: Business Process Modeling and Analysis
Subfield: Management Information Systems
Field: Business, Management and Accounting
Domain: Social Sciences
LHD ICHPXI #170857.1

Ion Cyclotron Range of Frequencies (ICRF) heating system to launch fast waves (Ion Cyclotron Range of Frequencies (ICRF) waves) to heat plasma particles by wave-particle interaction. Raw data are forward and reflected power and voltage of transmission lines, 3.5 U/L and 4.5 U/L.

Topic: Orthopedic Surgery and Rehabilitation
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Elaboration and Evaluation of Produced Hamburger with Meat of Old Sheep and Pig with Added of Chia Seed (Salvia hispanica)

The objective of this study was to develop some hamburger meat product aimed at harnessing meat of old sheep, of little acceptance in nature, with pork and chia seed. The better acceptance formulation was used to prepare three formulations the relationship being of sheep/pork of 50/50 (w/w) and chia seed concentrations of 0%, 2% and 4%. The results showed significant difference (p ˂ 0.05) acceptability among FA formulations (without chia seed) and FC (4% chia seed) at 120 days and between FC formulation at 90 and 120 days. The chemical composition was significantly affected by the addition of chia seed. The cooking weight loss was ranging from 11.6% (FC) to 19.29% (FA). In the evaluation of TBARS and IP it was verified interference in the formulations by the addition of chia seed. The use of chia seed these burgers can be recommended up to 4%.

Topic: Polysaccharides Composition and Applications
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Comparative study of the student's design process: Implications for the teaching of the later phases of the mechanical engineering design process

Most methods that guide the designer through the later phases of the design process are general in na-ture, and it is up to the designer to organize the design work using the tools and techniques available. This process also relies greatly on experience, which is quite a challenge for students, who are mostly novices in the area. In a comparative study, the evolution of the experience and skills acquired by the students in performing design tasks during the embodiment design and detail design phases has been analyzed. The re-sults indicate the main directions for improvement in teaching the later phases of the mechanical engineer-ing design process. 1.

Topic: Design Education and Practice
Subfield: Mechanical Engineering
Field: Engineering
Domain: Physical Sciences
Exploring the Effects of Cancer-Associated Mutations in Selected Cell Lines Using Online Computational Tools

<title>Abstract</title> This research aimed to investigate the mutations in selected cancer-related genes across three different cell lines: A549, NCI-H23, and NCI-H460. The genes of interest included HSP90AA1, TBL1XR1, ZFHX3, DDR2, LIFR, and MYH11, with a focus on their mutation profiles and potential impacts on cancer development. Various online programs, including PolyPhen-2, Mutation Master, and DynaMut, were employed to analyze the functional effects of mutations on the proteins encoded by these genes. Results indicated that HSP90AA1 and DDR2 had high Mutation Master scores, suggesting a strong association with disease. PolyPhen results showed that HSP90AA1 and ZFHX3 mutations were predicted to be probably damaging, while TBL1XR1 was classified as benign. The DynaMut analysis revealed significant changes in flexibility and stability for most mutations, particularly highlighting the destabilizing effects of TBL1XR1 and ZFHX3. The Swiss-Model results showed full green structures upon superposition of wild-type and mutant proteins, indicating minimal structural differences. However, the absence of results for ZFHX3 in Mutation Master due to missing transcript data emphasizes the challenges faced in mutation research. The findings provide insights into the mutation landscape of these genes, suggesting potential avenues for further investigation in cancer research.

Topic: Cancer Genomics and Diagnostics
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Coffee in Colombia, 1850–1970

In this book, Marco Palacios explores the history of Colombia as a coffee-producer, and the implications that coffee has had for its economy, society, and politics since the middle of the nineteenth century. He provides a history of the commercialization of the crop, and relates it to the general evolution of Colombian society, an evolution often determined by coffee even in areas remote from the crop itself. The book also covers the development of the specific institutions that have been set up to manage coffee affairs, and their role in the Colombian state. Since the last quarter of the nineteenth century coffee has been the mainstay of the Colombian economy, and no historian, economist, or sociologist interested in the country can escape its importance; nor can anyone interested in the commodity ignore Colombia. This is the first work on the subject to appear in English.

Topic: History and Politics in Latin America
Subfield: Demography
Field: Social Sciences
Domain: Social Sciences
&lt;b&gt;Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People with Type 2 Diabetes Mellitus&lt;/b&gt;

&lt;p dir="ltr"&gt;OBJECTIVE To identify genetic risk factors for incident cardiovascular disease (CVD) among people with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS We conducted a multi-ancestry time-to-event genome-wide association study for incident CVD among people with T2D. We also tested 204 known coronary artery disease (CAD) variants for association with incident CVD. RESULTS Among 49,230 participants with T2D, 8,956 had incident CVD events (event rate 18.2%). We identified three novel genetic loci for incident CVD: rs147138607 (near CACNA1E/ZNF648, HR 1.23, P=3.6×10-9), rs11444867 (near HS3ST1, HR 1.89, P=9.9×10-9), and rs335407 (near TFB1M/NOX3, HR 1.25, P=1.5×10-8). Among 204 known CAD loci, 5 were associated with incident CVD in T2D (multiple comparison-adjusted P &lt; 0.00024, 0.05/204). A standardized polygenic score of these 204 variants was associated with incident CVD with HR 1.14 (P=1.0×10-16). CONCLUSIONS The data point to novel and known genomic regions associated with incident CVD among individuals with T2D.&lt;/p&gt;

Topic: Genetic Associations and Epidemiology
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Cachexia in head and neck squamous cell carcinoma (HNSCC) patients (pts) after cisplatin-based chemoradiation (CRT): A cross-sectional study.

e23138 Background: Cachexia is a wasting syndrome that may affect HNSCC pts, contributing to their dismal prognosis. We aimed to study the frequency of cachexia in HNSCC survivors treated with CRT with curative intent. Methods: Cross-sectional study that included 120 consecutive pts from Jan/2014 to Feb/2017, over 18 y.o. and who were previously treated with definitive or adjuvant CRT for HNSCC (nasopharynx, oropharynx [OP], oral cavity [OC], hypopharynx and larynx [L]). Eligible pts were in regular follow-up for at least 2 years in the multidisciplinary team, with no evidence of disease. Medical history, body weight, height, mid-arm muscle circumference (MAMC) and muscle strength (MS, handgrip dynamometer) were measured, and laboratory tests (hemoglobin [Hb], albumin and C-reactive protein [CRP]) were obtained. Cachexia was diagnosed when there was any weight loss in the previous year, and at least 3 of the following: reduced grip muscle strength, fatigue, anorexia, low lean body mass, or laboratorial alterations (Hb &lt; 12 g/dL, serum albumin &lt; 3.2 g/dL or CRP &gt; 5.0 mg/L). A subjective assessment of nutritional status was made based on the Patient-Generated Subjective Global Assessment (PG-SGA) in its short form. Results: Median age 59 y.o. (21-78), 88 male (73%). Most common primary sites were OP (42%), L (24%) and OC (19%). Median follow-up was 42 mo. (24-125). There was a predominance of locally advanced disease at diagnosis: 73% T3/T4 and 72% N+. The mean weight was 64.5 kg (±14.6) pre-CRT, 57.8 kg (±12.2) post-CRT (p 0.02) and 63 kg (±11.8) in the present evaluation (p NS). Dysphagia was a complaint in 88 pts (73%). Cachexia was diagnosed in 42 pts (35%). As expected, cachectic pts (CP) presented lower MAMC (25.1 vs. 27.2 cm, p 0.0002) and MS (24.3 vs. 29.5 kgf, p 0.004). Higher mean CRP (12.7 vs. 4.2 mg/L, p 0.0001) and lower Hb (13.1 vs.13.9 g/dL, p 0.01) were also seen in CP. The PG-SGA score was higher in CP (7.9 vs. 5.7, p 0.006). Conclusions: Cachexia was frequently diagnosed in HNSCC pts with NED after CRT in a long-term follow-up, without evident weight loss. More effective preventive and therapeutic strategies are warranted. Supported in part by FAPESP grant 2014/00172-9.

Topic: Nutrition and Health in Aging
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
A Study on the Implementation of SIP based new Integrated Instant Messenger

IETF(Internet Engineering Task Force)에서 제안한 SIP(Session Initiation Protocol)는 텍스트 기반의 프로토콜로서 유연성과 뛰어난 확장성을 가지고 있어 다양한 응용 서비스에 적용할 수 있는 호 설정 프로토콜이다. 본 논문에서는 이러한 SIP를 기반으로 하여 사용자의 현재 상태에 관련된 정보를 알려주는 Presence 서비스 및 Presence 서비스에서의 Watcher 정보 서비스도 아울러 포함시킨 통합 인스턴트 메신저 시스템을 구현하였다. 이 시스템에서는 텍스트 기반의 인스턴트 메시지뿐만 아니라 음성 및 화상 통신도 가능하도록 하였다. 그리고 음성 및 화상통신의 경우 Presence 정보를 담는 PRESENCE TUPLE을 확장하여 Presence 서버가 통신에 필요한 각종 세션 정보를 저장하도록 함으로써 SIP INVITE 요청 메시지를 통한 다이얼로그의 생성 없이 직접 사용자간의 연결이 가능하도록 하는 새로운 방법을 제시하였다. SIP(Session Initiation Protocol) is a text based call signaling protocol that has characteristics such as flexibilities and extensibility for various application services over Internet. In this paper, we have implemented SIP based integrated Instant Messenger system which includes Presence Watcher Information service that can notify various current users status. In this system, voice and video communications are also possible as well as text based instant messages. For voice and video communication, we have newly proposed a method in which direct connection is possible between users without creation of SW INVITE dialog by extending PRESENCE TUPLE of presence information. In this case, PRESENCE TUPLE stores some informations necessary for the session.

Topic: IPv6, Mobility, Handover, Networks, Security
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Appearance of nuclear factors that interact with genes for myeloid calcium binding proteins (MRP-8 and MRP-14) in differentiated HL-60 cells

Myeloid calcium binding proteins MRP-8 and MRP-14 were induced, and their genes were coordinately expressed, during differentiation of human leukemia HL-60 cells into macrophage-like cells after treatment with 1,25-dihydroxyvitamin D3 (VD3). Both MRP-8 and MRP-14 mRNAs appeared on the day after VD3 treatment. Their level reached a peak on day 2, and then quickly declined. Nuclear factors that interact with the 5'-upstream regions of MRP-8 and MRP-14 genes were studied with gel mobility-shift assays. Two factors (MP8FI and MP8FII) that interacted with 379 bp (426–48 bp upstream from the transcription-initiation site of MRP-8 gene) and 67 bp (-47 – +20) DNA fragments, respectively, were found in the cells treated with VD3 for 1 day. MP8FI and MP8FII were present neither in the nuclei of untreated HL-60 cells, nor in the nuclei of the cells treated with VD3 for 6 days. Human monocytic leukemia THP-1 cells, which constitutively expressed MRP genes, had MP8FII but not MF8FI. MP8FII was found to interact with the 19-mer sequence located just upstream of the TATA box. Also, two factors that bound to the different upstream regions (-400 – -150 and -149 – +50) of MRP-14 gene were detected in the differentiated HL-60 cells. One of these, MP14FI, appeared on day 1, but on day 6 its concentration greatly decreased. The other, MP14FII, was found in greater quantity on day 6 than on day 1. MP14FI, but not MP14FII, was found in THP-1 cells. These factors may be involved in the expression of MRP-8 and MRP-14 genes in VD3-differentiated HL-60 cells.

Topic: S100 Proteins and Annexins
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Case Study on H Corp. Software Project Risk Management with ISM

The comprehensive risk management system based on the software project features of H Corp. is established, the causal relationships among risk factors are discovered, and corresponding risk structure model is built with ISM. Five original risk factors are found, including requirements analysis risk, project communication risk, schedule risk, risk of system design, and risk of project cooperation. Finally, some specific counter measures are put forward to help H Corp. improve the ability of software project risk management.

Topic: Software Engineering Techniques and Practices
Subfield: Information Systems
Field: Computer Science
Domain: Physical Sciences
Technical Guidelines for Reliable Measurements of the Quantized Hall Resistance

This paper describes the main tests and precautions that guarantee both reproducible and accurate results in the use of the quantum Hall effect as a means to establish a reference standard of resistance having a relative uncertainty of a few parts in 108.

Topic: Quantum and electron transport phenomena
Subfield: Atomic and Molecular Physics, and Optics
Field: Physics and Astronomy
Domain: Physical Sciences
Ruptured Dissecting Aneurysm of the Carotid Artery 12 Years after Gamma Knife Therapy for Pituitary Adenoma

The etiology of this pathology may have been a collapsed vasa vasorum or fibrosis of adventitia on the carotid wall adjacent to the irradiated site. We need to suspect this rare but serious pathology in patients with histories of irradiation of the cavernous region who develop massive hematemesis of unknown origin.

Topic: Intracranial Aneurysms: Treatment and Complications
Subfield: Neurology
Field: Medicine
Domain: Health Sciences