jimnoneill/paper-to-field-training huggingface dataset:
Is there any influence of personality disorder on the treatment of social phobia?

The aim of the study was to asses the efficacy of the 6 week therapeutic program designed for social phobia (SSRIs and CBT) in patients suffering with social phobia and comorbid personality disorder (17 patients) and social phobia without comorbid personality disorder (18 patients). Diagnosis was done according to the ICD-10 research diagnostic criteria confirmed with MINI. Patients were treated with CBT and antidepressants. They were regularly assessed in week 0, 2, 4, and 6 on the CGI (Clinical Global Improvement) for severity, LSAS (Liebowitz Social Anxiety Scale), and in self-assessments BAI (Beck Anxiety Inventory) and BDI (Beck Depression Inventory).

Topic: Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
Laser direct writing of submicron lines using micro- and nanofiber pens

In this paper, a novel direct writing technique using micro- and nanofiber pens is presented. The micro- and nanofiber pen serves as a tightly confined point source and it adopts micro touch mode in the process of writing. The energy distribution of direct writing model is analyzed by Three-Dimension Finite-Difference Time-Domain method. The lines with feature sizes down to 100 nm are experimentally achieved by this technique. Experiments also demonstrate that direct writing using micro- and nanofiber pens has some advantages: simple process, large writing area, and controllable width of lines. In addition, by altering writing direction of lines, complex submicron patterns can be fabricated.

Topic: Advanced Surface Polishing Techniques
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Environmental consciousness and brand equity

Purpose The purpose of this paper is to investigate the activities of environmental consciousness from socio-psychographic perspectives and hence evaluates its effect on brand equity through intervening elements of environmental attributes (EAt). It further attempts to research the effect of the environmental performance, environmental communication and environmental positioning in enhancing brand equity. Indian refrigeration industry, particularly the air conditioners and refrigerator brands are chosen to convey and receive the research inputs as their impact on environment is easily interpretable. Design/methodology/approach A hypothesized model comprising the environment consciousness and association dimensions with brand equity is framed. In total, 74 expert respondents from four state capital cities of India participated in the survey and the model has been tested in the scope of analytical hierarchy process (AHP). Findings The result shows that the EAt and activities can be prioritized and subsequently efficient resource allocation can be done. It also gives theoretical arguments to legitimize the environmental practices. Practical implications On the other hand, clients have numerous options, and a competitive advantage may not be maintained. Regardless of the fact that clients are environmentally conscious of a given refrigeration brand at the present time that they are utilizing, they may observe that they are much more charmed with a competitors’ enhanced environmental dimensions. All methods that take a try at an enhanced brand equity must be continually determined by environmental consciousness. The above can be accomplished if the evaluations of competitors by the clients are known. The AHP-ECBE technique depicted in this study accordingly helps refrigeration organization to devise and keep up a pertinent, focused plan for persistent improvements in environmental dimensions. It offers a “greater image” in brand equity administration. Originality/value If legitimately done in a generalized way, environmental activities like eco-literacy, interpersonal influence and value orientation can impact EAt and contribute in building brand equity.

Topic: Environmental Sustainability in Business
Subfield: Marketing
Field: Business, Management and Accounting
Domain: Social Sciences
Corrigendum to “Do Equine-assisted Physical Activities Help to Develop Gross Motor Skills in Children with the Down Syndrome? Short-term Results”

A misspelling of the first author's surname was inadvertently introduced in the process of making minor editorial adjustments to the final version of the article. His correct name should read 'Sergiy Voznesenskyy' (orcid.org/0000-0003-4037-8625). The correct citation should therefore be: Voznesenskyy, S., Rivera-Quinatoa, J. A., Bonilla-Yacelga, K. A., & Cedeño-Zamora, M. N. (2016). Do equine-assisted physical activities help to develop gross motor skills in children with the Down syndrome? Short-term results. Procedia - Social and Behavioral Sciences, 233, 307-312. doi: 10.1016/j.sbspro.2016.10.140

Topic: Pasture and Agricultural Systems
Subfield: Forestry
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Improvement of tribological properties of detonation carbosilicide coatings with subsequent pulsed-plasma treatment

This work considers the results of research of mechanical and tribological properties of surface layer of Ti3SiC2coatings after exposure to pulsed-plasma energy flows. Varying of technological parameters of pulsed-plasma treatment is made by changing the distance of pulse exposure. The analysis of the obtained results shows that the pulsed-plasma treatment technology makes it possible to improve the properties of Ti-SiC based coatings by strengthening the deposited compositions by modifying the structure with an increase in the number of МАХ-phases. It is established that the modification of the structural and phase state of the near-surface layers of the carbosilicide coatings leads to a change in their mechanical properties: an increase in the surface microhardness up to 1.8 times, a decrease in the dry friction coefficient by 1.5-2.0 times and an increase in wear resistance by 2.5 times. Based on the XRD analysis, it is established that the improvement of mechanical and tribological properties of Ti3SiC2 detonation coatings as a result of pulsed-plasma treatment is associated with phase transformations in the surface layer, in particular with an increase in the Ti3SiC2 phase content.

Topic: Metal and Thin Film Mechanics
Subfield: Mechanics of Materials
Field: Engineering
Domain: Physical Sciences
Construction Project Managers Skills, Client Satisfaction and Business Profitabilty in Selected Architectural Firms in Metro Manila

The construction industry is one of the world’s largest economic sectors, with global spending reaching $10.6 trillion in 2017 and projected to rise to $15.5 trillion by 2030 (Jackson, 2020). This study investigated the levels of project construction managers’ skills, client satisfaction, and business profitability in selected architectural firms in Metro Manila using a descriptive-correlational design. A total of 92 respondents were selected from 120 project construction managers through random sampling and surveyed using a validated and reliable instrument. Findings revealed very high ratings in construction management skills, client satisfaction, and business profitability. Resource and risk management were top-rated competencies, while clients highly valued timeliness, communication, and responsiveness. Although no significant relationship was found between management skills and client satisfaction, both were shown to positively influence profitability. Cost management emerged as the strongest predictor of financial success. In conclusion, high levels of project management skills and client satisfaction contribute to strong business profitability, emphasizing the critical role of cost management in sustaining financial performance in architectural firms.

Topic: Construction Project Management and Performance
Subfield: Management Science and Operations Research
Field: Decision Sciences
Domain: Social Sciences
Clinical and molecular problems of polycystic kidney disease.

Using nephrological, genealogical and molecular genetic methods, the authors examined 85 members of 19 families with autosomal dominant polycystic kidney disease. With the aid of probe 3'HVR, alpha-globin and restriction endonuclease Pvu II, the families were found 95% informative. The rate of diagnostic reliability was also 95%. The authors verified the homogeneity of the disease in the Czech population and the applicability of the probe and endonuclease for molecular gene diagnostics in the population.

Topic: Genetic and Kidney Cyst Diseases
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
[Relationship between the expression of hypoxia-inducible factor-1alpha and chemotherapy response in esophageal squamous cell carcinoma].

HIF-1alpha protein expression by immunohistochemistry may be a useful indicator to prediction the chemotherapy response and clinical outcome for esophageal squamous cell carcinoma.

Topic: Cancer, Hypoxia, and Metabolism
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Assessment of the maturity of E-Government Websites in the DR Congo

Many improvements to the connection<br> between government and citizens are brought about by<br> ICT evaluation. Through e-government websites, ICT has<br> given citizens a new way to interact with the government<br> at any time and from any location. In order to assess the<br> maturity of e-Government and the advancements the Congolese government is making towards the supply of e-<br> services, this paper evaluates the current condition of e-<br> government websites in the Democratic Republic of Congo using the United Nations Maturity Model of<br> Online development. The outcome demonstrated that<br> Democratic Republic of the Congo (DRC) e-government<br> websites is in the infancy stage as it performs well in the<br> first stage, relatively well in the second stages, but achieve<br> very little or nothing at the third and fourth stages.

Topic: E-Government and Public Services
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
Innate immunity in Arabidopsis : molecular mechanisms of HOPA1 and AVRRS4 - specific disease resistance signaling pathways

The entire thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file; a non-technical public abstract appears in the public.pdf file.

Topic: Plant-Microbe Interactions and Immunity
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Current status of global conservation and characterisation of wild and cultivated Brassicaceae genetic resources

Abstract Background The economic importance of the globally distributed Brassicaceae family resides in the large diversity of crops within the family and the substantial variety of agronomic and functional traits they possess. We reviewed the current classifications of crop wild relatives (CWRs) in the Brassicaceae family with the aim of identifying new potential cross-compatible species from a total of 1,242 species using phylogenetic approaches. Results In general, cross-compatibility data between wild species and crops, as well as phenotype and genotype characterisation data, were available for major crops but very limited for minor crops, restricting the identification of new potential CWRs. Around 70% of wild Brassicaceae did not have genetic sequence data available in public repositories, and only 40% had chromosome counts published. Using phylogenetic distances, we propose 103 new potential CWRs for this family, which we recommend as priorities for cross-compatibility tests with crops and for phenotypic characterisation, including 71 newly identified CWRs for 10 minor crops. From the total species used in this study, more than half had no records of being in ex situ conservation, and 80% were not assessed for their conservation status or were data deficient (IUCN Red List Assessments). Conclusions Great efforts are needed on ex situ conservation to have accessible material for characterising and evaluating the species for future breeding programmes. We identified the Mediterranean region as one key conservation area for wild Brassicaceae species, with great numbers of endemic and threatened species. Conservation assessments are urgently needed to evaluate most of these wild Brassicaceae.

Topic: Plant Ecology and Taxonomy Studies
Subfield: Ecology, Evolution, Behavior and Systematics
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Data from Phase I Dose-Escalation Study of the Multikinase Inhibitor Lenvatinib in Patients with Advanced Solid Tumors and in an Expanded Cohort of Patients with Melanoma

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; This “3+3” phase I study evaluated the safety, biologic, and clinical activity of lenvatinib, an oral multikinase inhibitor, in patients with solid tumors.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; Ascending doses of lenvatinib were administered &lt;i&gt;per os&lt;/i&gt; twice daily in 28-day cycles. Safety and response were assessed for all patients. Angiogenic and apoptotic factors were tested as possible biomarkers in an expanded melanoma cohort.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; Seventy-seven patients were treated in 3 cohorts: 18 with intermittent twice-daily dosing (7 days on, 7 days off) of 0.1–3.2 mg; 33 with twice-daily dosing of 3.2–12 mg; and 26 with twice-daily dosing of 10 mg (expanded melanoma cohort). Maximum tolerated dose was established at 10 mg &lt;i&gt;per os&lt;/i&gt; twice daily. Prominent drug-related toxicities included hypertension (43%), fatigue (42%), proteinuria (39%), and nausea (25%); dose-limiting toxicities included hypertension, fatigue, and proteinuria. Twelve patients (15.6%) achieved partial response (PR, &lt;i&gt;n&lt;/i&gt; = 9) or unconfirmed PR (uPR, &lt;i&gt;n&lt;/i&gt; = 3), and 19 (24.7%) achieved stable disease (SD) ≥23 weeks. Total PR/uPR/SD ≥23 weeks was 40.3% (&lt;i&gt;n&lt;/i&gt; = 31). Responses (PR/uPR) by disease were as follows: melanoma, 5 of 29 patients (includes 1 patient with &lt;i&gt;NRAS&lt;/i&gt; mutation); thyroid, 3 of 6 patients; pancreatic, 1 of 2 patients; lung, 1 of 1 patients; renal, 1 of 1 patients; endometrial, 1 of 4 patients; and ovarian, 1 of 5 patients. AUC&lt;sub&gt;0–24&lt;/sub&gt; and &lt;i&gt;C&lt;/i&gt;&lt;sub&gt;max&lt;/sub&gt; increased dose proportionally. In multivariate Cox proportional hazard model analyses, increased baseline systolic blood pressure and decreased angiopoietin-1 ratio (2 hours:baseline) were associated with longer progression-free survival (PFS) in the expanded melanoma cohort (&lt;i&gt;P&lt;/i&gt; = 0.041 and &lt;i&gt;P&lt;/i&gt; = 0.03, respectively).&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; The toxicity profile, pharmacokinetics, and antitumor activity of lenvatinib are encouraging. Decreases in the angiopoietin-1 ratio correlated with longer PFS in melanoma patients. &lt;i&gt;Clin Cancer Res; 21(21); 4801–10. ©2015 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;

Topic: Melanoma and MAPK Pathways
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
The Influence of Root Temperature on Nitrate Assimilation by Cucumber and Figleaf Gourd

In vivo nitrate reductase (NR) activity in roots of both cucumber (Cucumis sativus L. cv. Suyô) and figleaf gourd (Cucurbita ficifolia Bouchè) grown at a root temperature of 20°C was greatly reduced by low temperature of the enzyme assay medium. In contrast, NR activity in roots of plants grown at either 13° or 20°C root temperature did not differ, based on the temperature of incubation. Activity of root NR was very low compared to that of leaf NR, particularly in figleaf gourd.The fate of nitrate nitrogen (N) in plants exposed for 2h to K15NO3 solutions at either 13° or 20°C root temperature was determined by chase experiments for 8h in the light after transfer of plants to non-labeled media at the same temperatures as those used for exposure to 15N. Absorption of nitrate-15N at 13°C root temperature was significantly lower than that at 20°C, especially in cucumber. However, in both species the assimilation and translocation of absorbed nitrate-15N were little affected by root temperature. Roots of both species accumulated very slight amounts of reduced-15N. Most of 15N translocated to leaves was assumed to be in the form of nitrate.These results suggest that nitrate assimilation takes place predominantly in leaves in both cucumber and figleaf gourd, and that the nitrate assimilating capacity is not affected by low root temperature and therefore not responsible for the differential root-chilling tolerance of these plant species.

Topic: Plant nutrient uptake and metabolism
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Metaheuristics for (Variable-Size) Mixed Optimization Problems: A Unified Taxonomy and Survey

Many real world optimization problems are formulated as mixed-variable optimization problems (MVOPs) which involve both continuous and discrete variables. MVOPs including dimensional variables are characterized by a variable-size search space. Depending on the values of dimensional variables, the number and type of the variables of the problem can vary dynamically. MVOPs and variable-size MVOPs (VMVOPs) are difficult to solve and raise a number of scientific challenges in the design of metaheuristics. Standard metaheuristics have been first designed to address continuous or discrete optimization problems, and are not able to tackle (V)MVOPs in an efficient way. The development of metaheuristics for solving such problems has attracted the attention of many researchers and is increasingly popular. However, to our knowledge there is no well established taxonomy and comprehensive survey for handling this important family of optimization problems. This paper presents a unified taxonomy for metaheuristic solutions for solving (V)MVOPs in an attempt to provide a common terminology and classification mechanisms. It provides a general mathematical formulation and concepts of (V)MVOPs, and identifies the various solving methodologies than can be applied in metaheuristics. The advantages, the weaknesses and the limitations of the presented methodologies are discussed. The proposed taxonomy also allows to identify some open research issues which needs further in-depth investigations.

Topic: Metaheuristic Optimization Algorithms Research
Subfield: Artificial Intelligence
Field: Computer Science
Domain: Physical Sciences
Local disease control after stereotactic body radiotherapy in patients with neuroendocrine neoplasms: a cohort study

Our study suggests that SBRT may offer a feasible and effective treatment of neuroendocrine neoplasms in selected cases. SBRT provides long-term local stability and may be useful in treating patients with localised disease not fit for surgery.

Topic: Neuroendocrine Tumor Research Advances
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Flexible architecture of the ‘popsyandu’: An appropriate adaptable solution for urban kampung land - use issue

Urban kampung in Indonesia has the characteristics of a high population density living in a limited amount of land. Residents of an urban kampung require a space that can be used together to carry out communal activities. However, the limited amount of land in a kampung causes these activities to occupy whatever land is available which often has uncertain ownership status. A team from the Department of Architecture UI built 'Popsyandu' shelter in Kampung Palsigunung, Depok, West Java, using the 'flexible architecture' approach to respond to the needs and issues of the kampung. Using qualitative methods and data collection through observation and interview, this paper attempts to discuss the application of flexible architecture in the design of 'Popsyandu'. The result shows that the application of 'flexible architecture' approach is difficult to be comprehended by the residents of the kampung, even though the designers tried to involve the residents during the design and construction process. Therefore, the authors conclude that in adopting a flexible architecture to respond to certain issues, the designer must consider the capabilities of the user instead of just following the theories stated beforehand.&#x0D; © 2020 Dalhar Susanto, Widyarko, Nisrina Dewi Salsabila

Topic: Architectural and Urban Studies
Subfield: Conservation
Field: Arts and Humanities
Domain: Social Sciences
Extensive Aberrant Mongolian Spot

Abstract A 9‐month‐old male infant had generalized diffuse blue‐gray pigmentation over most of his body, sparing the scalp, face, neck, palms, soles, periumbilical area, genital area, and nipples. Within the lesion, there were several conspicuous macules of considerably darker hue. Histologic examination revealed numerous dermal melanocytes. By 16 months of age, the child's blue‐gray pigmentation had decreased substantially.

Topic: Dermatologic Treatments and Research
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Grasses of Chihuahua, Mexico

&lt;div&gt;Our revision of the grasses of Chihuahua includes 385 species in 95 genera, 15 subspecies, 29 varieties, and 4 forms. We provide keys for determination, detailed descriptions, nomenclatural synonyms, ecological information on habitat, distribution based on herbarium specimens, and illustrations for 251 species and 8 varieties. We provide a new combination for &lt;i&gt;Cenchrus polystachios&lt;/i&gt; subsp. &lt;i&gt;setosus&lt;/i&gt;. &lt;/div&gt;

Topic: Plant Taxonomy and Phylogenetics
Subfield: Ecology, Evolution, Behavior and Systematics
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Introduction: Pushing the Limits

Whenever I review an article submission to Theatre Research in Canada/Recherches théâtrales au Canada, one of the first questions I ask is: Does this article push the limits of theatre and performance studies in an exciting, provocative, or challenging way? Does it open up a fresh approach to existing material, shed light on an overlooked subject, excavate new primary sources, employ innovative methodologies, or introduce a novel theoretical approach? In short, does the article do something different for the discipline and does this difference matter? I am pleased to say that all six of the articles gathered in this issue of TRIC/RTAC push the limits of theatre and performance studies scholarship in diverse and engaging ways. This pushing continues in the excellent Forum section edited by Adriana Disman, which explores four of the performance art pieces she curated as part of the LINK &amp; PIN series in 2013-14.

Topic: Theatre and Performance Studies
Subfield: Visual Arts and Performing Arts
Field: Arts and Humanities
Domain: Social Sciences