jimnoneill/paper-to-field-training huggingface dataset:
Precision measurements, extra generations and heavy neutrino

The existence of extra chiral generations with all fermions heavier than $M_Z$ is strongly disfavored by the precision electroweak data. The exclusion of one additional generation of heavy fermions in SUSY extension of Standard Model is less forbidden if chargino and neutralino have low degenerate masses with $Δm \simeq 1$ GeV. However the data are fitted nicely even by a few extra generations, if one allows neutral leptons to have masses close to 50 GeV. Such heavy neutrino can be searched in the reaction $e^+ e^- \to N\bar{N}γ$ at LEP-200 with total final luminosity of $2600 pb^{-1}$.

Topic: Particle physics theoretical and experimental studies
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
Decreased Level of Nitric Oxide in Preeclamptic Pregnancy: A Relationship with PON1 Arylesterase Activity

Aims: The aim of the study was to evaluate the status and diagnostic utility of PON1. (Paraoxonase-1) Arylesterase and nitric oxide as indicator of antioxidant status in preeclampsia.&#x0D; Study Design: Analytical case control study.&#x0D; Place and Duration of Study: Sample: Department of obstretics and gynecology Department, G. M. C. Ambajogai, between July 2010 and July 2012.&#x0D; Methodology: We conducted a case-control study of 57 women with preeclampsia and 57 women with uncomplicated deliveries. We measured PON1 Arylesterase activity, Nitric oxide and lipid profile.&#x0D; Results: Serum levels of LDLc (low density lipoprotein cholesterol) are higher in cases than in controls and are statistically significant (p=0.023). However serum HDLc (high density lipoprotein cholesterol) levels are decreased significantly (p = 0.017). Serum PON1 Arylesterase showed significant decrease in cases152.68 KU/L versus controls 180.89 KU/L, p value=0.002. Serum nitric oxide also showed significant decrease in cases 22.77 ± 4.792 umol/L versus controls 25.127 umol/L, p=0.010. PON1 Arylesterase activity is found to be positively correlated with serum HDL cholesterol (r = 0.449, p value&lt; 0.001). Multivariate logistic regression analysis was done.&#x0D; Conclusion: Our observed results show decrease in the antioxidant PON1 Arylesterase activity point towards their role in the pathogenesis of Preeclampsia.

Topic: Paraoxonase enzyme and polymorphisms
Subfield: Clinical Biochemistry
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
The Impact of Nitrification on Soil Acidification and Cation Leaching in a Red Alder Ecosystem

Abstract The objectives of this study were to investigate the impacts of internal nitrification on soil and soil solution acidity and on the rate of nutrient export through NO 3 − mediated leaching. This was achieved by comparing soil chemical properties and soil solution composition within a naturally N‐rich red alder ( Alnus rubra Bong.) ecosystem to those of an adjacent Douglas‐fir [ Pseudotsuga menziesil (Mirbel) Franco] forest where soil N levels were significantly lower and no measurable HNO 3 production could be observed. In the red alder system, where &gt; 100 kg ha −1 yr −1 of N were added through symbiotic N 2 fixation, the net annual NO 3 − leaching past the 40‐cm soil depth amounted to 3460 mol charges ha −1 , and NO 3 − concentrations in the solutions collected below 40 cm periodically exceeded drinking water standards of 10 mg L −1 . The H + and NO 3 − release was most pronounced in the forest floor and top 10 cm of the soil under alder occupancy and caused significant acidification of percolating solutions. Less than 1% of the total H + input from internal (nitrification) and external (atmospheric) sources leached below the 40‐cm depth, which was indicative for the strong buffering capacity of this particular soil. The cation displacement reactions involved in this pH buffering caused a 15% decline in base saturation and a significant acidification of the upper part of the soil profile. The presence of large amounts of mobile NO 3 − in solution triggered accelerated cation leaching, causing a selective redistribution of primarily exchangeable Ca 2+ from the A to the B horizon. These field studies lead us to conclude that the rate and the selectivity of NO 3 − mediated leaching in a red alder system could significantly lower the exchangeable cation pool in the rooting zone or cause nutrient imbalance, if a site is managed for repeated rotations of red alder.

Topic: Soil Carbon and Nitrogen Dynamics
Subfield: Soil Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
"Living the dream" atop Whistler Mountain : the malaise of modernity and Vancouver's leisure culture

Our modern age is purportedly like a mountain; high and mighty, worthy in stature and significance. Perhaps we live in the Everest era, atop the summit of achievements in science, technology, and innovation. If so, then modernity should be viewed as untroubled progress. Yet Charles Taylor's malaise of modernity presents us with a rather different view. Given the pervasive logics of individualism, instrumental reason, and a loss of freedom, the onward march of modernity should perhaps be met with more resistance. Taylor charges us to recognize such inherent contestation. The case study of a leisure culture in Vancouver, British Columbia, sheds light on this tension. An elite class of young urban professionals is observed to respond to Taylor's malaise by escaping and returning to nature, notably the Coast Mountains. Twenty in-depth interviews were conducted to examine their refusals of the metropolitan auspices of the malaise, manifest in the pursuit of heroism, awe and wonder, and vitality, all of which reify mountain culture. Yet the call and response are far from simple. Rather, a riddle of sorts emerges. Given the logics, technologies, and terrain of escape, the grip of the malaise seems as tight on the mountainside as in the metropolis. Taylor serves as a valuable guide in this fraught terrain. His 'work of retrieval' informs a pursuit of the richer sources feeding this culture. Logics of social atomism, fragmentation, and instrumentalism are examined. In doing so, a critique of radical anthropocentrism is mounted, challenging the young professionals’ attitudes towards fulfillment. Does this quest for meaning negate nature, society, history, tradition, and even God? These questions reveal potential limits to the modern frame, in its individualized, secularized, and subjectivized versions. The mountain emerges as a powerful conceptual image amidst this analysis. In times of clarity and confusion, the permanence and perspective of the mountain are to be treasured. Whilst Leopold's call of 'Thinking like a Mountain' is considered, the limitations of a mountainous group, in the Coast Mountains, atop the 21st Century informational mountain are duly noted. The hope is that Taylor's 'work of retrieval' can, after all, enlarge the frame.

Topic: Sport and Mega-Event Impacts
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Functionalization of poly(bis‐thiophene methine)s via facile C–C bulk polymerization and their application as chemosensors for acid detection

ABSTRACT Up to now, 3,4‐ethylenedioxythiophene (EDOT) or its modified analogs are indispensable units or subunits in all successful monomers for polythiophene synthesis through solid‐state polymerization (SSP). Here, a more open thiophene‐(CH(R))‐thiophene platform was developed successfully and corresponding poly(bis‐thiophene methine)s were obtained via C–C SSP or melt‐state polymerization (MSP), that is, bulk polymerization. Meanwhile, the observation of quite long effective Br–Br distance of 5.634 Å, which is more than 50% of halogen's double van der Waals radius (2 r w ), would help us to understand powerful capability of modulation of molecule movement and reaction under SSP. In addition, these polymers were further employed as acid sensors and they show highly sensitive response to HCl, MeSO 3 H, BF 3 ‐OEt 2 , and HNO 3 . The detailed experiment reveals that P1 has the detection limit of 3.35 × 10 −5 M for HCl. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018 , 56 , 1676–1683

Topic: Conducting polymers and applications
Subfield: Polymers and Plastics
Field: Materials Science
Domain: Physical Sciences
Advancing Newborn Screening Long-Term Follow-Up: Integration of Epic-Based Registries, Dashboards, and Efficient Workflows

The Connecticut Newborn Screening (NBS) Network, in partnership with the Connecticut Department of Public Health, strategically utilized the Epic electronic health record (EHR) system to establish registries for tracking long-term follow-up (LTFU) of NBS patients. After launching the LTFU registry in 2019, the Network obtained funding from the Health Resources and Services Administration to address the slow adoption by specialty care teams. An LTFU model was implemented in the three highest-volume specialty care teams at Connecticut Children’s, involving an early childhood cohort diagnosed with an NBS-identified disorder since the formation of the Network in March 2019. This cohort grew from 87 to 115 over the two-year project. Methods included optimizing registries, capturing external data from Health Information Exchanges, incorporating evidence-based guidelines, and conducting qualitative and quantitative evaluations. The early childhood cohort demonstrated significant and sustainable improvements in the percentage of visits up-to-date (%UTD) compared to the non-intervention legacy cohort of patients diagnosed with an NBS disorder before the formation of the Network. Positive trends in the early childhood cohort, including %UTD for visits and condition-specific performance metrics, were observed. The qualitative evaluation highlighted the achievability of practice behavior changes for specialty care teams through responsive support from the nurse analyst. The Network’s model serves as a use case for applying and achieving the adoption of population health tools within an EHR system to track care delivery and quickly fill identified care gaps, with the aim of improving long-term health for NBS patients.

Topic: Genomics and Rare Diseases
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
The Application of Principle of Formative Assessment in the Classroom Teaching of English Methodology

The summative assessment is now giving way to the formative assessment in English teaching.The wide application of the formative assessment can provide a fast feedback for the teacher and the student.It can improve the quality of teaching,develop students' interest in learning and promote an overall development of the students.

Topic: Educational Technology and Assessment
Subfield: Information Systems
Field: Computer Science
Domain: Physical Sciences
Molecular Characterization of Multi-drug Resistant Streptococcus pyogenes and Its Eradication Using Essential Oil of Zingiber officinale as a Natural Antimicrobial Agent

M ULTIDRUG-resistant (MDR) Streptococcus pyogenes is implicated in a variety of diseases.S. pyogenes has been found to produce novel enzymes to break down antibiotics more than most other bacteria.This study aimed to detect and to identify S. pyogenes in some clinical samples by serotyping method especially multidrug resistant S. pyogenes with detection and sequencing of meF and ermB genes responsible for Macrolide resistance, parC gene responsible for Quinelone resistance and folP gene responsible for Sulfonamide resistance and using essential oil of Ginger (Zingiber officinale) as a natural treatment agent for MDR S. pyogenes strains.S. pyogenes was detected in 60/120 throat and blood samples (50.0%).36/60 samples were found to be multidrug resistant.Men were more likely infected than women.The results indicated that 52.8% of S. pyogenes isolates harbored meF gene, 72.2% harbored ermB gene, 100.0%harbored parC gene and 100.0%harbored folP gene while 25% of them harbored the four genes.The sequencing alignment of meF, ermB, parC and folP genes showed some mutations in the four genes ranged between inversion mutation in meF gene, substitution mutation in ermB and parC genes and deletion and inversion mutations in folP gene.Zingiber officinale essential oil was analysed by GC-MS which illustrated that 17-Octadecynoic acid was the most common ingredient with percentage of 48.27%.20µg/ml was found to be the minimal bactericidal concentration (MBC).

Topic: Ginger and Zingiberaceae research
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
[Location of PERIFIX SOFT epidural catheter investigated by X-ray].

It is known that the course of catheter placement is related to the firmness of catheter. This paper reports the results of roentgenographic analysis of the location of catheters (20G PERIFIX SOFT catheter-B. Braun Melsungen-blind tip with three side holes) inserted into the lumbar epidural space in 20 patients. Epidural catheterization was performed in patients on the lateral decubitus position. The epidural space was identified by the loss of resistance technique with a 17 gauge Tuohy needle, with median approach. Post-operatively, the injection of 0.5 ml radiopaque solution (Iopamidol) through the catheter was made. A-P X-ray film showed that 70 per cent of epidural catheters were inserted straightly cephalad. It has been reported that the optimum hardness and blind tip of the catheter are required for the good epidural placement. PERIFIX SOFT epidural catheter showed the good result for this purpose. From the recent anatomical observation by MRI, epi-dural space takes various figures depend on the location. Since posterior median part is the widest part in lumbar region, catheter placement should be done in this area. This will increase the success of straight placement of the epidural catheter.

Topic: Spine and Intervertebral Disc Pathology
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Modulation of NK Cell Autocrine-Induced Eosinophil Chemotaxis by Interleukin-15 and Vitamin D<sub>3</sub>: A Possible NK-Eosinophil Crosstalk via IL-8 in the Pathophysiology of Allergic Rhinitis

Natural killer cells (NK) secrete eosinophilotactic cytokines, however, whether they contribute to eosinophil chemotaxis by secreting IL-8 is not known. We investigated the ability of CD56+CD3-ve (NK cells) to induce chemotaxis of peripheral blood eosinophils from allergic rhinitis (AR) patients, through IL-8 secretion, and the effects of IL-15, the NK cell proactivating cytokine, and calcitriol: 1α, 25-dihydroxy Vitamin D 3 (vitamin D 3 ), the immunomodulator agent, in this scenario. Herein, it is shown that supernatants from unstimulated NK cells exhibited chemotactic activity against eosinophil. This effect was significantly augmented by IL-15 (1 ng/mL) treatment, resulting in an increase in the chemotactic index of approximately 3 folds and was abrogated by neutralizing antibody (Ab) to IL-8 in a dose-dependent fashion. The amount of IL-8 secreted by NK cells was increased by IL-15 treatment from levels of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mn>88.64</mml:mn><mml:mo>±</mml:mo><mml:mn>21.5</mml:mn></mml:mrow></mml:math>to<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mn>178.9</mml:mn><mml:mo>±</mml:mo><mml:mn>23.6</mml:mn></mml:mrow></mml:math> Pg/mL and was significantly reduced by 10 -6 M vitamin D 3 to levels of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:mn>59.2</mml:mn><mml:mo>±</mml:mo><mml:mn>16.3</mml:mn></mml:mrow></mml:math> Pg/mL. Our results indicate a novel inflammatory crosstalk between NK cells and eosinophils via IL-15/IL-8 axis that can be modulated by vitamin D 3 .

Topic: Asthma and respiratory diseases
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
ChemInform Abstract: Telomerization of Isoprene with Phthalimide by Complex Palladium Catalysts.

Abstract Telomerization of phthalimide (I) with isoprene (II) in the presence of palladium complex affords a mixture of two isomeric N‐dimethyloctadienylphthalimides.

Topic: Catalytic Cross-Coupling Reactions
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Ventilation of the Baltic Sea deep water: A brief review of present knowledge from observations and models

The ventilation of the Baltic Sea deep wateris driven by either gale-forced barotropic or baroclinic salt water inflows.During the past two decades, the frequency of large barotropic inflows(mainly in winter) has decreased and the frequency of medium-intensity baroclinic inflows(observed in summer) has increased. As a result of entrainment of ambient oxygen-rich water,summer inflows are also important for the deep water ventilation.Recent process studies of salt water plumes suggest that the entrainmentrates are generally smaller than those predicted by earlier entrainment models.In addition to the entrance area, the Słupsk Sill andthe Słupsk Furrow are important locations for the transformation of water masses. Passing the Słupsk Furrow, both gravity-driven dense bottom flows and sub-surface cyclonic eddies,which are eroded laterally by thermohaline intrusions,ventilate the deep water of the eastern Gotland Basin.A recent study of the energy transfer from barotropic to baroclinicwave motion using a two-dimensional shallow water model suggests thatabout 30% of the energy needed below the halocline for deep water mixingis explained by the breaking of internal waves.In the deep water decade-long stagnation periods with decreasingoxygen and increasing hydrogen sulphide concentrations might be caused by anomalously largefreshwater inflows and anomalously high mean zonal wind speeds. In differentstudies the typical response time scale of average salinity was estimated tobe between approximately 20 and 30 years.The review summarizes recent research resultsand ends with a list of open questions and recommendations.

Topic: Oceanographic and Atmospheric Processes
Subfield: Oceanography
Field: Earth and Planetary Sciences
Domain: Physical Sciences
Retrograde-Delivered Cardioplegia Is Not Distributed Equally to the Right Ventricular Free Wall and Septum

Comment The right ventricle is at risk of receiving inadequate protection from retrograde cardioplegia. The ventricular free wall is particularly at risk if the balloon catheter is placed beyond the first branch of the coronary sinus. Technical enhancements to transesophageal echocardiography continue to be made. The authors demonstrated one of these advances with a mediodology that measures the real time, right ventricular distribution of retrograde-administered cardioplegia. They showed that the right ventricular free wall is indeed at risk for receiving inadequate protection. This capability may enhance the use of transesophageal echocardiography for cardiopulmonary bypass surgery. These investigators wisely warn us of die limitations of retrograde cardioplegia. How antegrade cardioplegia fits into this scenario or whether some other solution will be used remains to be determined.

Topic: Congenital Heart Disease Studies
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
PENGARUH BUDAYA ORGANISASI TERHADAP PERILAKU IHSAN PERAWAT MELALUI PERSONAL VALUES PADA RUMAH SAKIT ISLAM GONDANGLEGI MALANG

Abstract: Every organization must have a culture that guides the organization. Someone will work seriously ifin a comfortable atmosphere and working environment. The purpose of this study was to find out how big inthe organizational culture directly or indirectly that influenced the Nurses Ihsan Behavior at GondanglegiIslamic Hospital of Malang. Type of research used a quantitative research model with descriptive or surveyapproach that aimed at testing the predefined hypothesis. The object of this study was conducted atGondanglegi Islamic Hospital of Malang. The sample used 72 respondents with non-probability samplingtechnique. The result indicated that the organizational Culture had direct and significant effect to NursesIhsan Behavior. The Organizational Culture had significant effect to Ihsan Behavior through Personal Values.It meant that if in the organizational culture and personal values increase, then the Nurses Ihsan Behavior willalso increase variable.

Topic: Healthcare Quality and Satisfaction
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
CCDC 647821: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
A comparison of the health effects of water supply and sanitation in urban and rural Guatemala.

Researchers analyzed 1987 data on 2008 75% of children had access to a flush toilet) was basically the same for both urban and rural ares (31.5% and 33.3% respectively). Further the risk of stunting was the same in a high level of sanitation area whether or not they had individual access to a flush toilet. Thus sanitation should receive the same attention and resources as water supply in water and sanitation programs whose goal it is to improve health. The importance of sanitation is universal. The most important goal and evaluation indicator should be achieving a community level of sanitation in which at least 75% of the people have access to sanitary facilities and uses them properly.

Topic: Child Nutrition and Water Access
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
A Low-Power Fully Implantable 15-Channel Retinal Stimulator Chip

Retinal prostheses are being developed around the world in hopes of restoring useful vision for patients suffering from certain types of diseases like age-related macular degeneration (AMD) and retinitis pigmentosa. The central component of an electrical retinal prosthesis is a wirelessly powered and driven stimulator chip. The chip receives commands from the outside and outputs biphasic current pulses to an electrode array placed in the retina that stimulate the remaining retinal neurons. The chip contains 30\thinspace000 transistors in a 0.5 mum technology (two-poly three-metal, 2P3M), occupies an area of 2.3 mm x 2.3 mm, and excluding the current sources consumes less than 2 mW of power. The chip is powered inductively via a 125 kHz power signal which is rectified to generate a plusmn2.5 V supply. The data signal is transmitted as an amplitude shift keyed (ASK) signal on a 13.56 MHz carrier. The data rate can be varied from 25 to 714 kHz and the symbol (0 or 1) is encoded as the pulse width of the data signal. A self-biased feedback-loop-based single-to-differential converter restores the signal to full rail levels. Clock and data recovery is performed by a self-biased low-power inverter-based delay-locked loop (DLL). The chip can receive four commands, and each command is 16 bits long. The current amplitude, pulse duration, and inter-pulse duration can be programmed by using the four commands.

Topic: Neuroscience and Neural Engineering
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Supplementary Figure 3 from Regulation of DNA Polymerase POLD4 Influences Genomic Instability in Lung Cancer

Supplementary Figure 3 from Regulation of DNA Polymerase POLD4 Influences Genomic Instability in Lung Cancer

Topic: Cancer-related molecular mechanisms research
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences