Hepatitis C Virus in Saliva

Letters1 April 1995Hepatitis C Virus in SalivaXavier Mariette, Pascale Loiseau, and Frederic MorinetXavier MarietteHopital Saint-Louis, Paris 75010, France., Pascale LoiseauHopital Saint-Louis, Paris 75010, France., and Frederic MorinetHopital Saint-Louis, Paris 75010, France.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-122-7-199504010-00021 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We investigated the prevalence of hepatitis C virus (HCV) in saliva because it is still controversial [1-3] and because lymphocytic sialadenitis of the Sjogren syndrome was associated with HCV infection in previous reports [4]. Serum and saliva samples were obtained on the same day from 28 patients with HCV infection and HCV viremia (13 of them were also infected with the human immunodeficiency virus [HIV]). Whole saliva was collected after the patients chewed gum for 10 minutes. Polymerase chain reaction using the Amplicor HCV test (Roche Diagnostic Systems, Branchburg, New Jersey) was used to detect HCV RNA. ...References1. Takamatsu K, Koyanagi Y, Okita K, Yamamoto N. Hepatitis C virus in saliva (Letter). Lancet. 1990; 336:1515. Google Scholar2. Fried MW, Sindo M, Fong TL, Fox PC, Hoofnagle JH, Di Bisceglie AM. Absence of hepatitis C viral RNA from saliva and semen of patients with chronic hepatitis C. Gastroenterology. 1992; 102:1306-8. Google Scholar3. Young KC, Chang TT, Liou TC, Wu HL. Detection of hepatitis C virus RNA in peripheral blood mononuclear cells and in saliva. J Med Virol. 1993; 41:55-60. Google Scholar4. Haddad J, Deny P, Munz-Gotheil C, Ambrosini JC, Trinchet JC, Pateron D, et al. Lymphocytic sialadenitis of Sjogren's syndrome associated with chronic hepatitis C virus liver disease. Lancet. 1992; 339:321-3. Google Scholar5. Akahane Y, Kojima M, Sugai Y, Sakamoto M, Miyazahi Y, Tanaka T, et al. Hepatitis C virus infection in spouses of patients with type C chronic liver disease. Ann Intern Med. 1994; 120:748-52. Google Scholar Author, Article, and Disclosure InformationAffiliations: Hopital Saint-Louis, Paris 75010, France. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byHCV clearance from saliva of HIV-HCV-coinfected patients on treatment with interferon plus ribavirinSaliva specimen sampling: a noninvasive method for diagnosis and basic investigation of viral hepatitis A, B and CHepatitis C virus quantification in serum and saliva of HCV-infected patientsXerostomia in the ElderlyDetection of Hepatitis C Virus-RNA in Saliva from Chronically HCV-Infected PatientsDetection of HCV-RNA in Saliva of HIV-HCV Coinfected PatientsTransmission of hepatitis C virus by saliva?Transmisión de la hepatitis C esporádica en el ámbito odontológicoAn update of the etiology and management of xerostomiaDetection of HCV RNA in saliva of patients with hepatitis C virus infection by using a highly sensitive testWhole stimulated salivary flow in patients with chronic hepatitis C virus infectionQuantitation of hepatitis C virus RNA in saliva and serum of patients coinfected with HCV and human immunodeficiency virusDetection of Hepatitis C Virus RNA From Gingival Crevicular Fluid and Its Relation to Virus Presence in SalivaLymphomas in Patients with Sjögren's Syndrome: Review of the Literature and Physiopathologic HypothesisPredominance of HCV type 2a in saliva from intravenous drug usersDetection and genotyping of the hepatitis C RNA in tear fluid from patients with chronic hepatitis CNonhepatic manifestations and combined diseases in HCV infection 1 April 1995Volume 122, Issue 7Page: 556KeywordsAntibodiesHepatitis C virusInfectious hepatitisOropharynxPolymerase chain reactionRNASalivaSemenSjogren syndromeViremia ePublished: 15 August 2000 Issue Published: 1 April 1995 Copyright & PermissionsCopyright © 1995 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

Topic: Hepatitis C virus research
Subfield: Hepatology
Field: Medicine
Domain: Health Sciences