jimnoneill/paper-to-field-training huggingface dataset:
Actinomycosis of the middle turbinate

Actinomycosis is an uncommon bacterial disease caused by actinomyces. Cervicofacial infection accounts for more than 60% of all cases. However, nasal and paranasal sinus involvement has rarely been described. We report herein a case of a patient presenting with middle turbinate actinomycosis.

Topic: Actinomycetales infections and treatment
Subfield: Microbiology
Field: Medicine
Domain: Health Sciences
The effect of information systems and human resources strategies on the success of information systems: Evidence from Jordanian commercial companies

The study aims at measuring the impact of human resources and information systems strategies on the success of information systems in the industrial companies operating in the Amman stock exchange. The study sample was made up of accounting and finance departments for these companies. The initial data were collected through a questionnaire that designed for this purpose. The results have confirmed a strong impact of information systems strategies on the information systems success. As well, the results have confirmed the impact of information systems strategies on human resources strategies. The study also has proved that human resources strategies have maintained a weak effect on the success of information systems. The study recommends the researchers in this field to re-study this subject by modifying the measuring variables methods, and study other economic sectors.

Topic: Technology Adoption and User Behaviour
Subfield: Information Systems and Management
Field: Decision Sciences
Domain: Social Sciences
Machine Vision Using Image Gradients for Spray-Deposit Analysis: Software Development

Software was developed to automatically analyze images of spray deposits on planar surfaces. Spot boundaries, which are extracted using image gradients rather than gray-level thresholds, are used to calculate spot and drop size distributions, spot counts, and coverage. The software was tested with spots ranging in size from 100 to 1600 mm generated on kromekote paper. Effects of spot contrast, orientation of oblong spots, camera aperture setting, and magnification on spot count and measured size were evaluated. Counting and sizing errors of 1 to 2% are possible with appropriate magnification and contrast.

Topic: Plant Surface Properties and Treatments
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
The Distinctions Between State, Parameter and Graph Dynamics in Sensorimotor Control and Coordination

The dynamical systems underlying the performance and learning of skilled behaviors can be analyzed in terms of state-, parameter-, and graph-dynamics. We review these concepts and then focus on the manner in which variation in dynamical graph structure can be used to explicate the temporal patterning of speech. Simulations are presented of speech gestural sequences using the task-dynamic model of speech production, and the importance of system graphs in shaping intergestural relative phasing patterns (both their mean values and their variability) within and between syllables is highlighted.

Topic: Language and cultural evolution
Subfield: Cultural Studies
Field: Social Sciences
Domain: Social Sciences
Significance of Serum Carotenoid Levels as a Biomarker of Hyperglycemia Estimated by HbA1c Measurement among Male Workers in an Industry

某事業所の男性技術系従業員 (320名) および事務系従業員 (177名) について, ヘモグロビンA1c (HbA1c) 値から見た高血糖者における自覚症状や食生活習慣, 野菜類摂取などの生体指標である血清カロテノイド値などの特徴を検討した。その結果, 事務系従業員の高血糖者では, 野菜類摂取の低頻度や血清α-およびβ-カロテンなどのカロテノイド値が低い者が多かったが, 技術系従業員ではこの関連が認められなかった。一方, 技術系従業員では眠れない, 夜トイレに起きるなど精神的負荷要因を有する者が多かった。したがって, 事務系従業員のヘモグロビンA1c5.6%以上の高血糖者には, 血清β-カロテン値を高めるなど緑黄色野菜類摂取などの生活環境要因など, 技術系従業員では, 精神的負荷要因などの健康指導が重要であることが推測された。

Topic: Adipose Tissue and Metabolism
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Preparatory Time–Related Hand Surgery Operating Room Inefficiency: A Systems Analysis

Background: No study exists on preparatory time—from patient’s entrance into the operating room to skin incision—and its role in hand surgery operating room inefficiency. The purpose of this study was to investigate the length and variability of preparatory time and assess the relationship between several variables and preparatory time. Methods: Consecutive upper extremity cases performed for a period of 1 month by hand surgeons were reviewed at 3 surgical sites. Preparatory time was compared across locations. Cases at one location were further analyzed to assess the relationship between preparatory time and several variables. Both traditional statistical methods and Shewhart control charts, a quality control tool, were used for data analysis. Results: A total of 288 cases were performed. The mean preparatory times at the 3 sites were 25.1, 25.7, and 20.7 minutes, respectivley. Aggregated preparatory time averaged 24.4 (range 7-61) minutes, was 75% the length of the surgical time, and accounted for 34% of total operating room time. Control charts confirmed substantial variability at all locations, signifying a poorly defined process. At a single site, where 189 cases were performed by 14 different surgeons, there was no difference in preparatory time by case type, American Society of Anesthesiologists status, or case start time. Preparatory time varied by surgeon and anesthesia type. Conclusions: Preparatory time was found to be a source of inefficiency, independent of the surgical site. Control charts reinforced large variations, signifying a poorly designed process. Surgeon seemingly plays an important, albeit likely indirect, role. Efforts to improve operating room workflow should include preparatory time.

Topic: Healthcare Operations and Scheduling Optimization
Subfield: Emergency Medical Services
Field: Health Professions
Domain: Health Sciences
Unsupervised Machine Learning for Analysis of Phase Separation in Ternary Lipid Mixture

Phase separation in mixed lipid systems has been extensively studied both experimentally and theoretically because of its biological importance. A detailed description of such complex systems undoubtedly requires novel mathematical frameworks that are capable of decomposing and categorizing the evolution of thousands if not millions of lipids involved in the phenomenon. The interpretation and analysis of molecular dynamics (MD) simulations representing temporal and spatial changes in such systems are still a challenging task. Here, we present an unsupervised machine learning approach based on nonnegative matrix factorization called NMFk that successfully extracts latent (i.e., not directly observable) features from the second layer neighborhood profiles derived from coarse-grained MD simulations of a ternary lipid mixture. Our results demonstrate that NMFk extracts physically meaningful features that uniquely describe the phase separation such as locations and roles of different lipid types, formation of nanodomains, and timescales of lipid segregation.

Topic: Lipid Membrane Structure and Behavior
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Some Possible Attentional Aspects of Post-Stimulus Signal Processing

Some possible attentional aspects of post-stimulus signal processing were investigated in a modified masked-signal detection paradigm. The signal was a 1000-Hz sinusoidal waveform 20 msec in duration and sated at positive zero-crossing of the waveform. The signal was masked by a broad-band (360–3360 Hz) Gaussian noise. The effect of a decrease in the amplitude of the masking noise, when confined to a limited frequency range, was investigated in terms of both the frequency range of the change and the temporal relationship between the offset of the signal observation interval and the onset of the decrease. An immediate decrease in masking noise in frequency regions outside the critical band of the signal decreased detectability.

Topic: Neural Networks and Applications
Subfield: Artificial Intelligence
Field: Computer Science
Domain: Physical Sciences
476 Induced hindgut acidosis in sheep affected gut permeability and ruminal fermentation

Abstract Leaky gut may be caused by acidotic conditions in the hindgut and lead to systemic inflammation and negative effects on the gastrointestinal tract. The objective was to determine the effects of induced hindgut acidosis in sheep on cecal pH, ruminal fermentation, and gut permeability. Ruminally and cecally cannulated ewes [n = 11; body weight (BW) = 49 ± 4 kg] were assigned to one of two treatments: control (CON; n = 5) or induced hindgut acidosis (HGA; n = 6). To induce hindgut acidosis, 3 g wheat starch/kg BW per 24 h was continuously infused via the cecal cannula for 4 d. Control ewes received a constant infusion of deionized water. The diet contained 40% grass hay pellets, 35% whole shelled corn, 15% dried distillers grains, and 10% alfalfa cubes. Chromium EDTA was dosed once daily via the cecal cannula as a marker of gut permeability. Rumen, cecal, and fecal samples were collected to determine pH and volatile fatty acids (VFA). Rumen fluid was collected on d 4 for an ex vivo fermentation. Flasks were incubated for 24 h to determine pH, VFA, ammonia and in vitro dry matter digestibility. Tissue samples from the ileum, cecum, and colon were mounted in Ussing chambers to measure transepithelial electrical resistance (TEER). There was a treatment × time effect (P = 0.05) for cecal pH with HGA ewes having lesser cecal pH after d 1. By d 4, cecal pH had declined to 5.07 for HGA ewes compared with CON ewes which remained above 6.40 throughout the experiment. A treatment × time interaction was also observed (P &amp;lt; 0.01) for fecal pH and followed the same trend as cecal pH. Rumen pH was not affected (P = 0.87) by the interaction of treatment and time but was affected (P &amp;lt; 0.01) by treatment as ewes on the HGA treatment had a lesser rumen pH than CON ewes. Control ewes had lesser ruminal VFA and ammonia concentrations than HGA ewes (P &amp;lt; 0.01). Urinary Cr recovery was not affected by the interaction of treatment and time, or treatment (P ≥ 0.13). In vitro dry matter disappearance was not affected by cecal infusion treatment (P = 0.60). There was no effect (P = 0.78) of treatment on ex vivo pH. There were no effects (P ≥ 0.11) of treatment, time, or their interaction on ex vivo ammonia or total VFA concentration. In cecal tissue, TEER tended (P = 0.09) to be greater in CON ewes than HGA ewes. In contrast, TEER was not different (P ≥ 0.83) in ileal or colonic tissues between treatments. Induced hindgut acidosis in sheep altered rumen fermentation and tended to increase ex vivo measures of cecal permeability, but did not affect ex vivo rumen fermentation.

Topic: Ruminant Nutrition and Digestive Physiology
Subfield: Agronomy and Crop Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
The Makara in Early Chinese Buddhist Sculpture

In the early Buddhist cave temples made in the latter half of the fifth century a.d., during the Northern Wei dynasty, at Yim-kang, in the Shansi Province of North China, can be found several carvings of a curious creature connected with the arches over a seated Buddha figure. It occurs at either end of the arch, the end merging into the hinder part of the creature, which is left with two legs, a long neck, and head. The body is turned away from the arch so that the two creatures are back to back, one at each end of the arch. Examples can be seen in Dr. Sirén's Chinese Sculpture from the Fifth to the Fourteenth Century , plates 51, 55, 57, 59, 60, and 61, in Tokiwa Daijo and Sikeno Tadaishi's Buddhist Monuments in China , vol. ii, plates 22 (2), 27, 30 (2), and 40, and in Chavannes' Mission archèologique dans la Chine septentrionale , plates 255, 256, 262–8, 272, and 277. Its representation was thus of common occurrence but nobody seems to have ventured to identify the creature. It is true that Dr. Sirén, with reference to plate 60 mentioned above, described the two arches being supported by two hydras and again wrote of the hydra and phœnix-like birds which support the foils of the arches, but he goes no further than this vague description.

Topic: Chinese history and philosophy
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Cyclosporine-induced adenosine triphosphate depletion in murine T and B lymphocytes.

Adenosine metabolism in C57BL/6 mouse spleen cells was studied. Adenosine triphosphate (ATP) levels in resting T cells were 26.9 +/- 3.4 ng/10(5) cells compared with 16.5 +/- 3.1 ng/10(5) cells in resting B cells. Cyclosporine (CSA) caused a prompt and severe ATP depletion in both T and B cells, which could be mitigated by the addition of adenosine. B cell ATP levels were returned to normal while T cell levels were only partially restored. The adenosine deaminase inhibitor erythro-9-(2 hydroxy-3 nonyl) adenine (EHNA) also caused ATP depletion in T and B cells, which could similarly be prevented in part by the addition of adenosine. However, when CSA and EHNA were combined, adenosine could no longer protect ATP pools and severe ATP depletion in T and B cells occurred. This suggests that CSA and EHNA affect different steps in the conversion of adenosine to ATP. Although both T and B cell ATP levels were affected by CSA, the ability of supplementary substrate to restore ATP levels to normal in B cells but not in T cells may explain the apparent selective effect of CSA impairing T cell functions with sparing of B cell functions. Furthermore, if causing ATP depletion is associated with immunosuppressive activity, EHNA may be useful in potentiating the immunosuppressive effects of CSA.

Topic: Adenosine and Purinergic Signaling
Subfield: Physiology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Developing Wheat Varieties for Whole Grain Artisanal Baking

AuthorsAllison Krill-Brown,1 Teng Vang,2 and Claudia Carter2 Affiliations1 University of California Davis. 2 California Wheat Commission. © 2019 AACC International, Inc.

Topic: Wheat and Barley Genetics and Pathology
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
P &amp; W 6512 277

•\nHOCKFOHD.\n" I do,., . aid the young lady: ' · and l must not n·­main\nhere, but go and adjust my hair.··\nl\\11·. Rockford en tered hastily, followed by :-:.cha ... tian.\nwho was the only one of the party that could keep pace\nwith the lengthy . tt·ides of the excited and happy Gov­ernor,\nwho, npproachin~ the place where :\\Irs. Rockfonl\nwas standing, f'a i&lt;l :\n" Oh ! J osephine, (;od has IH':trd our prayer. Seha.-:­tian,\nbehold your mother! ..\n~We mnsL let the t'nrlain fa ll npon this. ccnc.\n1J1·of ton has improveLl won\\lerfully ;::ince the abuut­tion\nQf ,'(•bastian. Samuel Cuh·erhouse aml Dorothy\nkwc been sleeping for many years under the sod. .J o­sephus\nNapoleon 13onaparte Snibbens married l\\iiss .Je­rush~~\nSmith. J lc named hiR first child Joachim Napo­leon\n::\\I nr:1t ife~· · lie has not yet completed his knowl­edge\nof the dns. i &lt;:~ . lmt it is hoped that he may &lt;lo '&gt;ll\nbefore he \\lit• . .\n' There wa; a grand fc. tival at the hou~e of ::Hr. Hoek-ford\nwithin a few weeks after Sebastian had been re­stored\nto his father. Captain Wal ingham was then·\nto give away the bride. Corolan and his wife antl ~fr.\n~Janning aml his ' rife were there.\nAll "Who were present declared that Sebastian an&lt;l\nE lfrida. were the finest couple that eyer knelt nt th&lt;'\naltn r.\n•

Topic: Magnetic confinement fusion research
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
UTILIZATION OF ANTIBIOTICS IN PATIENTS WITH URINARY TRACT INFECTIONS – A STUDY

The objective of this study was to assess and analyze the prescribing pattern, rationality of antibacterial, to study medication related problems and resistance/sensitivity patterns of antibiotics in patients with urinary tract infections. The observational prospective study was conducted in 100 patients with UTI at MVJ medical college and research hospital, Bangalore, India for six months. All required patient data were collected in specially designed case report form. Prescribing patterns, medication related problems and rationality were assessed. The average number of drug per encounter was 7.02. More than 63% of prescription had more than five drugs. Brand names of drug were prescribed more than the generic names. Fluroquinolones (norfloxacin) was mostly prescribed. Female population was more. Age group of &gt;58 years old was most prevalent. Monotherapy of antibiotic was more than combination therapy. Most of the possible drug interactions were moderate type. Norfloxacin was most frequently interacting antibiotic. No significant medication errors were identified. Rationality was assessed to be rational. The most common type of pathogen was E.coli. Antibacterial prescribing patterns and rationality of the medications were appropriate but, using drug brand names can increase the chance of medication related problems. Higher number of comorbidities was leading to polypharmacy which can increase possibility of drug-drug interactions therefore there is an increased requirement for close monitoring and management of these possible interactions. E. coli, K. pneumoniae and P. aeruginosa were more sensitive to nitrofurantoin, amikacin and norfloxacin therefore these may be the antibiotics of choice for the treatment of community-acquired UTIs.

Topic: Urinary Tract Infections Management
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Cavity assisted spin reconfiguration in a quantum wire

In the present work, we investigate the source-drain bias spectrum of a hybrid quantum device consisting of a dot-like QPC coupled to an electronic cavity. A singlet-triplet transition manifested as finite-bias anomaly is observed when the cavity is switched on. Besides, we noticed that the 0.7 conductance anomaly is not affected by the cavity, which provides a valuable insight on the origin of the 0.7 conductance anomaly.

Topic: Quantum and electron transport phenomena
Subfield: Atomic and Molecular Physics, and Optics
Field: Physics and Astronomy
Domain: Physical Sciences
Time-resolved x-ray crystallography capture of a slow reaction tetrahydrofolate intermediate

Time-resolved crystallography is a powerful technique to elucidate molecular mechanisms at both spatial (angstroms) and temporal (picoseconds to seconds) resolutions. We recently discovered an unusually slow reaction at room temperature that occurs on the order of days: the in crystalline reverse oxidative decay of the chemically labile (6S)-5,6,7,8-tetrahydrofolate in complex with its producing enzyme Escherichia coli dihydrofolate reductase. Here, we report the critical analysis of a representative dataset at an intermediate reaction time point. A quinonoid-like intermediate state lying between tetrahydrofolate and dihydrofolate features a near coplanar geometry of the bicyclic pterin moiety, and a tetrahedral sp3 C6 geometry is proposed based on the apparent mFo-DFc omit electron densities of the ligand. The presence of this intermediate is strongly supported by Bayesian difference refinement. Isomorphous Fo-Fo difference map and multi-state refinement analyses suggest the presence of end-state ligand populations as well, although the putative intermediate state is likely the most populated. A similar quinonoid intermediate previously proposed to transiently exist during the oxidation of tetrahydrofolate was confirmed by polarography and UV-vis spectroscopy to be relatively stable in the oxidation of its close analog tetrahydropterin. We postulate that the constraints on the ligand imposed by the interactions with the protein environment might be the origin of the slow reaction observed by time-resolved crystallography.

Topic: Porphyrin Metabolism and Disorders
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Cowboy Jack

Performer: Esmereldy and Dick Thomas; Frank Novak And The Sourwood Mountain Boys Duet. Digitized at 78 revolutions per minute. Four stylii were used to transfer this record. They are 3.8mil truncated conical, 2.3mil truncated conical, 2.8mil truncated conical, 3.3mil truncated conical. These were recorded flat and then also equalized with Turnover: 375.0, Rolloff: -12.0. The preferred versions suggested by an audio engineer at George Blood, L.P. have been copied to have the more friendly filenames. Matrix number: 5153 Catalog number: 298-B Other IDs from the record include: (5153)

Topic: African history and culture analysis
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
Molecular identification and high fidelity micropropagation of shell ginger (Alpinia zerumbet)

Alpinia zerumbet is a medicinal and ornamental plant of the Zingiberaceae family cultivated in many parts of the world. The plant is medicinally important and often misidentified with closely related species. The objective of this work was to establish its DNA-based identity and a protocol for high-fidelity micropropagation to support the medicinal plant industry. PCR amplification and subsequent sequencing of RuBisCO large subunit (rbcL) and Maturase K (matK) gene successfully report its DNA barcode. In vitro shoots were induced the best from rhizome buds on Murashige and Skoog (MS) medium supplemented with 6.0 mg L−1 6-benzyl amino purine and 30 g L−1 sucrose. Microshoots were rooted well in MS medium amended with 1.5 mg L−1 naphthalene acetic acid. Plantlets were satisfactorily acclimated to soils maintained in a growth chamber and subsequently in the open air for 10–20 days. Analyzing eight random amplified polymorphic DNA and eight inter-simple sequence repeat primers resulted in 53 and 60 distinct bands, respectively. Uniform banding patterns suggest the genetic uniformity of the micropropagated plants. The results offer an accurate identification of A. zerumbet from any plant tissue. The micropropagation protocol would be helpful for economically feasible and environmentally sustainable exploitation of this valuable plant.

Topic: Ginger and Zingiberaceae research
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
Multichannel SPR biosensor for detection of environmentalcontaminants

An increasing number of chemical and biological substances are
released into the environment every year as a result of
industrial and agricultural activity (e.g., polycyclic aromatic
hydrocarbons, pesticides and surfactants). In order to protect
the public health and local ecosystems from the harmful effects
of these compounds, efficient tools for their rapid detection
are urgently needed. Currently, detection of harmful
contaminants is performed using established analytical
techniques, such as gas chromatography, liquid chromatography,
and mass spectrometry. SPR biosensors for environmental
monitoring present an interesting alternative to these
conventional methods and offer numerous attractive features
such as ease of use, low cost, portability, and the ability to
perform detection in the field. Within this communication, we
report a novel portable SPR immunosensor for detection of
environmental contaminants exhibiting endocrine disrupting
effects.

Topic: Advanced biosensing and bioanalysis techniques
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences