jimnoneill/paper-to-field-training huggingface dataset:
Prediction of V <sub>s30</sub> in Datong Basin and Amplification Effect of Site Ground Motion Based on Typical Geological Characteristics Analysis

Abstract Shear wave velocity of soil layer is an important dynamic parameter, which is of great significance for site classification, determination of ground motion parameters and prediction of ground motion. Based on the analysis of shear wave velocity data of 1429 geological boreholes in Datong Basin, this paper studies the relationship between V S and geological characteristics such as soil type, geological unit type, SPT blow number and compactness degree. Based on the correlation analysis of shear wave velocity ratio of soil, soil compactness coefficient and thickness of Quaternary upper overburden, this paper presents a soil V S30 prediction model. The goodness of fit R 2 &gt; 0.90 and the prediction accuracy is very high under the overall sample condition. Based on the abundant strong earthquake records and drilling information of KiK-net and K-net networks in Japan, V S30 and site period T S are selected as the two quantitative indexes of the amplification effect of site ground motion. The correlation between V S30 and PGA amplification coefficient and site period T S is established. The distribution characteristics of PGA amplification coefficient and site period T S based on V S30 distribution are given. The results show that the maximum values of PGA amplification coefficient and T S distribution characteristics of site period are consistent with the geological location of the earthquake swarm with M6.1 in 1989 in Datong Basin. It shows that the characteristics of the site ground motion effect estimated by V S30 can indicate the occurrence of earthquakes. The occurrence of earthquakes is affected by active faults and local conditions of the site at the same time, which fully proves the feasibility of this research method and the accuracy of the research results. The shear wave velocity ratio and the soil compactness coefficient are proposed for the first time, and they are applied to the prediction of V S30 with the thickness of the upper overburden of the quaternary system. This paper provides a good research idea for V S30 prediction of non-shear wave velocity test site, study of amplification effect of site ground motion, study and judgment of earthquake location. The research results can provide important technical support for urban earthquake prevention and mitigation planning, large earthquake scenario construction, earthquake risk analysis, earthquake damage prediction and regional earthquake safety evaluation in Taiyuan Basin.

Topic: Seismic Performance and Analysis
Subfield: Civil and Structural Engineering
Field: Engineering
Domain: Physical Sciences
Factors related to the first use of tobacco in Secondary School Students

Objective: To study the prevalence of smoking in students of Secondary Education at IES Valley and the factors that lead to the first use of snuff. Methods: Cross-sectional study on a sample of 123 students obtained through convenience sampling. The information was collected by a self-administered questionnaire that included variables of age, sex,

Topic: Health and Lifestyle Studies
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
Controversy over the scope of the term “medical care” in the context of its exemption from value added tax

Generally, health care services that are intended to prevent, save, restore, and improve health are exempt from VAT. However, not every activity meets the requirements set by EU or national law. The rules regarding VAT exemptions for medical services are not precise enough to avoid controversy. Case law and tax interpretations help determine whether a medical service is exempt. However, it is not consistent. It is problematic to assess whether comprehensive services, services related to plastic surgery, and recently also medical advice by phone or internet are eligible for VAT exemption. These problems were signaled in the article.

Topic: Health Systems, Economic Evaluations, Quality of Life
Subfield: Economics and Econometrics
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Path dependency, regional variety and the dynamics of new firm creation in rooted and pioneering industries

Abstract This paper explores regional firm entry connecting insights on the role of localised path dependency with the analysis of variety in regional sectoral structures. Using data on 700 SIC5 industries across 174 NUTS3 regions in the UK between 2000 and 2014, we provide evidence of positive complementarities between industrial path dependence and regional-related variety for firm entry in rooted pre-existing industries. These are negative for entry of pioneering firms in industries new to the region, pointing to lock-in effects and the role of unrelated variety in fostering linkages and knowledge spillovers away from established trajectories.

Topic: Regional Economics and Spatial Analysis
Subfield: Economics and Econometrics
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Gas recombination device design and cost study. Final report

Under a contract with Argonne National Laboratory, VARTA Batterie AG. conducted a design and cost study of hydrogen-oxygen recombination devices (HORD) for use with utility load-leveling lead-acid cells. Design specifications for the devices, through extensive calculation of the heat-flow conditions of the unit, were developed. Catalyst and condenser surface areas were specified. The exact dimensions can, however, be adjusted to the cell dimension and the space available above the cell. Design specifications were also developed for additional components required to ensure proper function of the recombination device, including metal hydride compound decomposer, aerosol retainer, and gas storage component. Costs for HORD were estimated to range from $4 to $10/kWh cell capacity for the production of a large number of units (greater than or equal to 10,000 units). The cost is a function of cell size and positive grid design. 21 figures, 2 tables.

Topic: Energetic Materials and Combustion
Subfield: Mechanics of Materials
Field: Engineering
Domain: Physical Sciences
Data from Targeting the WASF3–CYFIP1 Complex Using Stapled Peptides Suppresses Cancer Cell Invasion

&lt;div&gt;Abstract&lt;p&gt;Activation of the WASF3 protein by extracellular stimuli promotes actin cytoskeleton reorganization and facilitates cancer cell invasion, whereas WASF3 depletion suppresses invasion and metastasis. In quiescent cells, the interaction between WASF3 and a complex of proteins, including CYFIP1, acts as a conformational restraint to prevent WASF3 activation. Therefore, we took advantage of this endogenous regulatory mechanism to investigate potential sites that disrupt WASF3 function. Here, we show that genetic knockdown of CYFIP1 in cancer cells led to the destabilization of the WASF3 complex, loss of WASF3 function, and suppressed invasion. Based on existing crystallographic data, we developed stapled peptides, referred to as WASF Helix Mimics (WAHM), that target an α-helical interface between WASF3 and CYFIP1. Treatment of highly invasive breast and prostate cancer cells with WAHM inhibitor peptides significantly reduced motility and invasion &lt;i&gt;in vitro&lt;/i&gt;. Mechanistic investigations revealed that these inhibitors suppressed the interaction between Rac and the WASF3 complex, which has been shown to promote cell migration. Furthermore, peptide-mediated inhibition of WASF3 also resulted in the dysregulation of known downstream targets such as MMP-9 and KISS1. Finally, we demonstrate that this invasive phenotype is specific to WASF3 as depletion of WASF1 and WASF2, which can also bind to CYFIP1, did not affect invasion. Collectively, our findings suggest that targeting WASF3 function with WAHM peptides could represent a promising therapeutic strategy for preventing tumor invasion and metastasis. &lt;i&gt;Cancer Res; 76(4); 965–73. ©2015 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;

Topic: Machine Learning in Bioinformatics
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Application in Up-Flow Filtration of Filter Material for Urban Stormwater Control

In this research, a up-flow filtration device was developed for the on-site treatment of urban stormwater runoff during storm events, and particle removal characteristic of porous polypropylene as a filter material was experimentally examined. The up-flow filtration device showed high removal efficiency, more than 90% (mainly 95-98%) of the SS concentration of influent particles. After the sedimentation in the bottom part of up-flow filtration device, the up-flow filtration filled with porous polypropylene material was able to remove more over 70% of the SS concentration in the up-flow. The increase rate of captured particle amount retained in 10, 20 cm from the bottom of filter bed was lower while flow rate increased. This is attributed to the fact that fine particles detached or not removed by the bottom of filter bed were mainly retained in that section. The particles (mainly finer particles) captures were increased by those particles (mainly large particles) retained in the initial stage for influent particles. However, the improvement of particle removal efficiency (as SS concentration) was not observed along with this phenomenon. The reason may relate to the fact that the particles retained by the captured particles in the initial stage were fine particles.

Topic: Urban Stormwater Management Solutions
Subfield: Environmental Engineering
Field: Environmental Science
Domain: Physical Sciences
193-nm photodissociation of acryloyl chloride to probe the unimolecular dissociation of CH2CHCO radicals and CH2CCO

The work presented here uses photofragment translational spectroscopy to investigate the primary and secondary dissociation channels of acryloyl chloride (CH2=CHCOCl) excited at 193 nm. Three primary channels were observed. Two C–Cl fission channels occur, one producing fragments with high kinetic recoil energies and the other producing fragments with low translational energies. These channels produced nascent CH2CHCO radicals with internal energies ranging from 23 to 66 kcal/mol for the high-translational-energy channel and from 50 to 68 kcal/mol for the low-translational-energy channel. We found that all nascent CH2CHCO radicals were unstable to CH2CH+CO formation, in agreement with the G3//B3LYP barrier height of 22.4 kcal/mol to within experimental and computational uncertainties. The third primary channel is HCl elimination. All of the nascent CH2CCO coproducts were found to have enough internal energy to dissociate, producing CH2C:+CO, in qualitative agreement with the G3//B3LYP barrier of 39.5 kcal/mol. We derive from the experimental results an upper limit of 23±3 kcal/mol for the zero-point-corrected barrier to the unimolecular dissociation of the CH2CHCO radical to form CH2CH+CO.

Topic: Atmospheric chemistry and aerosols
Subfield: Atmospheric Science
Field: Earth and Planetary Sciences
Domain: Physical Sciences
Synthesis, stereochemistry, and bonding of tetrapyridinemagnesium(II) bis(.pi.-cyclopentadienyltricarbonylmolybdate(I-)) and related compounds

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis, stereochemistry, and bonding of tetrapyridinemagnesium(II) bis(.pi.-cyclopentadienyltricarbonylmolybdate(I-)) and related compoundsS. W. Ulmer, P. M. Skarstad, J. M. Burlitch, and R. E. HughesCite this: J. Am. Chem. Soc. 1973, 95, 13, 4469–4471Publication Date (Print):June 27, 1973Publication History Published online1 May 2002Published inissue 27 June 1973https://pubs.acs.org/doi/10.1021/ja00794a080https://doi.org/10.1021/ja00794a080research-articleACS PublicationsRequest reuse permissionsArticle Views92Altmetric-Citations65LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Topic: Ferrocene Chemistry and Applications
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Activities of human recombination protein Rad51

Homologous pairing and strand exchange, which are catalyzed by Escherichia coli RecA protein, are central to homologous recombination. Homologs of this protein are found in eukaryotes; however, little has been reported on the recombinase activities of the mammalian homologs, including the human protein, denoted HsRad51. For the studies described here, we purified HsRad51 from E. coli . Although the activities of HsRad51 and RecA were qualitatively similar in the presence of ATP, there were also striking differences. The stoichiometry of binding to DNA and the rate of renaturation of complementary strands were similar for the two proteins, but rates of ATP hydrolysis, homologous pairing, and subsequent strand exchange promoted by HsRad51 were less than (null)/1;10 those of RecA. In addition, HsRad51 bound γ-thio-ATP and formed stable presynaptic complexes that promoted renaturation as rapidly as RecA, but the recombinant human protein catalyzed neither strand exchange nor homologous pairing of a single strand with duplex DNA in the presence of the ATP analog. By contrast, RecA promoted both of the latter reactions in control experiments. These observations suggest that among RecA-like proteins, HsRad51 may be a variant in which homologous pairing and strand exchange are more closely linked to the hydrolysis of ATP.

Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Primary cilia in cancer cells

Primary cilia are sensory organelles that exist on the surface of most cells. Since primary cilia play an important role in cell cycle and cilia‐related signaling pathways (e.g. Hedghog and Wnt signaling pathways), ciliary dysfunction has been proposed as an essential factor of cancer development. In our current study, we characterized the expression of the primary cilia in two breast cancer (MCF7 and MDA132), two prostate cancer (PC3 and DU145), and one lung cancer (NL20‐TA) cell lines by counting number of cilia formation and measuring cilia length. We also examined the effect of shear stress on the cilia number and cilia length. Moreover, we investigated the correlation between primary cilia and cilia‐related signaling pathways. We found that the frequency and the length of the primary cilia were reduced in MCF7 and MDA‐MB‐231 breast cancer cells and in PC3 prostate cancer. Primary cilia were absent in DU‐145 prostate cancer and NL20‐TA lung cancer. The β‐catenin of Wnt signaling pathway was elevated in the prostate and lung cancers, while Gli1 and smoothened of Hedghog pathway remained the same. Our results suggested an association between primary cilia and Wnt signaling in cancer cells. This abstract is from the Experimental Biology 2019 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .

Topic: Genetic and Kidney Cyst Diseases
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Mentoring and the emotions

Drawing on data from nine secondary school mentor teachers, the authors explore the emotional aspects of mentoring. Embracing a view of 'cool' professionalism, the mentors hid from their interns the intensity and complexity of their work as mentors. The authors argue that to maximize the value of mentoring neophyte teachers should be given a glimpse into its difficulty as part of engaging in rich conversations about teaching and learning.

Topic: Teacher Education and Leadership Studies
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Retrospective comparison of costs between medical and surgical treatment of canine pyothorax.

This study compared costs of treating dogs with pyothorax medically versus surgically. Medical records from the University of Wisconsin School of Veterinary Medicine were searched for cases of pyothorax that underwent either medical or surgical treatment. Patients undergoing surgery were subdivided into early (ES; < 48 h) and late (LS; > 48 h) surgery groups. Costs and length of stay were compared between treatment groups. Treatment costs were adjusted for inflation. Nineteen dogs were included in analysis; 7 in the medical group (MG), 5 in the ES group, and 7 in the LS group. Total costs were significantly lower in the MG than in the LS group. Total costs were less for the MG than the ES group, and for ES than LS, but the differences did not achieve significance. Preoperative costs were higher in the LS than the ES group. We conclude that surgery for canine pyothorax is less costly if pursued earlier than later.

Topic: Pleural and Pulmonary Diseases
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Efficacy of Argel (Solenostemma argel (Del) hayne) Shoots’ Extract in the Control of the Red Flour Beetle (Tribolium castaneum Herbst)

Laboratory studies were conducted to evaluate the efficacy ofaqueous and organic extracts of the argel (S. argel) shoots against the 4thlarval instar and adult stages of the red flour beetle (Tribolium castaneum)in the Sudan. Argel shoots were extracted sequentially by organic solventsof increasing polarity (petroleum ether, ethyl acetate and ethanol) as wellas directly by distilled water or ethanol. Extracts were tested atconcentrations ranging between 1% and 10%. The evaluated efficacyparameters were mortality, repellency and antifeedant effects. The testswere conducted in Petri dishes (9 cm i.d) and plastic cups (capacity 200ml) and the obtained data were subjected to the analysis of variance and tothe probit analysis. The results of the mortality data indicated thatpetroleum ether extracts was the most potent against the 4 th larval instar ofT.castaneum as shown by its low LD50 of 8.2%, while ethyl acetateextract was the most potent against the adult of this pest with an LD50value of 16%. The results showed that various types of argel shootextracts induced significant dose dependent repellency against theT. castaneum. The highest 24 hours repellency was caused by thepetroleum ether extract on the adult stage of T. castaneum as indicated byits low ED50 value of 1.58%.The different argel shoot extracts inducedsignificant antifeedant action against the test insect. The lowest feedingratio (0.02) was recorded in ethyl acetate extract- treated crushed wheatgrains

Topic: Insect Pest Control Strategies
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
The Cephalostatins. 23. Conversion of Hecogenin to a Steroidal 1,6-Dioxaspiro[5.5]nonane Analogue for Cephalostatin 11

Cephalostatin 1 (1) has proved to be a remarkably potent cancer cell growth inhibitor. Since this steroidal alkaloid constituent of the marine worm Cephalodiscus gilchristi possesses a complex structure, providing preclinical supplies by total synthesis continues to be challenging. Therefore, syntheses of less complex structural modifications of this important pyrazine have also received substantial attention. Herein are summarized the synthesis of [5.5]spiroketal 5, a simplified right-side steroidal unit of 1, in seven steps from hecogenin acetate (11) with an overall yield of 4.6%. Consistent with other SAR studies, such reduction in structural complexity compared to 1 led to loss of cancer cell growth inhibitory activity against the P388 lymphocytic leukemia cell line.

Topic: Marine Sponges and Natural Products
Subfield: Biotechnology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Climate Policy after 2012

Discussion over post-2012 climate policy is now entering a crucial phase. Despite the potential great risks of prolonged global warming, the success of an international climate stabilization agreement hinges to a great extent on its economic feasibility. This article makes precise the assumptions that underpin current mainstream estimates of the costs of controlling climate change and provides quantitative estimates of cost differentials under different scenarios. In particular, the article analyses the role of three utmost factors in the economic cost of a climate treaty: energy technology development; the participation rate of developing countries; and the timing of global action. We show that all three factors have a major impact on policy macroeconomic costs. Addressing them effectively is therefore indispensable in ensuring the feasibility of any international agreement to control global warming. Therefore, we propose a series of policy recommendations that can help addressing the issues of technology, timing and participation, and that represent key policy implications for a post-2012 climate policy. (JEL codes: C72, H23, Q25, Q28) Copyright The Author 2009. Published by Oxford University Press on behalf of Ifo Institute for Economic Research, Munich. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org, Oxford University Press.

Topic: Economic Growth and Productivity
Subfield: Economics and Econometrics
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Propagation of photons and massive vector mesons between a parity breaking medium and vacuum

The problem of propagation of photons and massive vector mesons in the presence of Lorenz and CPT invariance violating medium is studied when the parity-odd medium is bounded by a hyperplane separating it from the vacuum. The solutions in both half-spaces are carefully discussed and in the case of space-like boundary stitched on the boundary with help of the Bogolubov transformations provided by the space-like Chern-Simons vector. The presence of two different Fock vacua is shown and the probability amplitude for transmission of particles from vacuum to parity breaking medium is calculated. We have also found classical solutions and showed that the results are consistent with ones obtained by canonical quantization formalism. In the cases, both of entrance to and of escaping from parity-odd medium, the probabilities for reflecting and passing through were found for each polarization using the classical solutions. Finally, the propagator for each polarization is obtained in the momentum space. Boundary effects under consideration are of certain importance for registration of local parity violation in the finite volume of heavy ion fireball and/or of a star with cold axion condensate.

Topic: Advanced Synthetic Organic Chemistry
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences