jimnoneill/paper-to-field-training huggingface dataset:
Role of AA-NAT and TPH1 in the Ghrelin-Dependent Regulation of Melatonin Secretion in Sheep during Different Seasons: An &lt;em&gt;In Vitro&lt;/em&gt; Study

Several studies suggests that ghrelin (GHRL) has neurobiological effects that extend beyond control of food intake. Our previous results confirmed that GHRL modulates the secretory activity of the pineal gland (PG) through nocturnal melatonin (MEL) secretion in sheep, the seasonally reproductive animals. Here we investigated the effects of GHRL (10 ng/ml) on the expression of enzymes limiting synthesis of MEL, including tryptophan 5-hydroxylase 1 (TPH1), serotonin N-acetyltransferase (AA-NAT) and its phosphorylated form p31T-AA-NAT in sheep PG explants (n = 72) during the 4-hour incubation in a gas-liquid interface, at a short (SD) and long (LD) photoperiods. After each hour of incubation selected explants were frozen in liquid nitrogen and stored at -80&amp;deg;C for subsequent analysis (real-time PCR, western-blotting, ELISA). Results show that GHRL regulates nightly MEL secretion in a TPH1-independent manner. The factor modulating GHRL activity was photoperiod. During SD photoperiod GHRL significantly reduced the expression of p31T-AA-NAT, AA-NAT and inhibited MEL secretion from PG explants. Whereas, during LD photoperiod no effect of GHRL on MEL secretion and expression of examined enzymes was noted. Studies indicate that GHRL directly affects PG under in vitro conditions and causes MEL secretion in animals which exhibit seasonality in reproductive and metabolic processes.

Topic: Regulation of Appetite and Obesity
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
CCDC 639506: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
HIV-related knowledge and attitude among dental patients attending a Nigerian teaching hospital

Objective: To examine the HIV-related knowledge and attitude among dental patients attending a Nigerian teaching hospital.
Methods: This questionnaire based cross-sectional study among dental patients University of Benin Teaching Hospital, Benin City was conducted between August, 2016 and October, 2017.
Results: Three-quarters (73.1%) of the participants had poor HIV knowledge. Participants less and equal to 20years, males and never married participants had poorer HIV knowledge. Most of the participants had favourable attitude (66.9%) towards HIV. Most of the participants that were more religious had favourable attitude towards HIV.
Conclusion: This study revealed that majority of the participants had poor HIV-related knowledge and a minority of the participants exhibited negative/intermediate attitude towards People Living with HIV/AIDS (PLWHA). There is a need to activate HIV-related education and promotion in the dental clinic setting. Efforts at improving religious attendances may be necessary to help reduce negative/intermediate attitude towards PLWHA

Topic: HIV, Drug Use, Sexual Risk
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Love and/ or Lyric: Dickinson's “I cannot live with You-”

This chapter considers Emily Dickinson’s F706—the poem which begins, “I cannot live with You-.” But F706 does rather more than just explain why its speaker cannot live with her beloved; it also explains why the two can neither die nor rise together. Critics often link Dickinson to metaphysical traditions, and this chapter also considers Dickinson’s poem “metaphysical” in the sense that this book articulates: it invests in a virtual form of love at least as much as in an actual, and uses poetry’s affordances to realize a love, in this case a recessive one, in which the speaker finds a distinctive non-sovereign freedom. Dickinson’s speaker empties the lyric present and puts in its place imagined stories that she then refuses but that nonetheless have power: that saturate her as a lyric subject and her stanzas as a lyric moment in which speaker, beloved, and reader “meet apart.” If Hegel, this chapter’s principal philosophical interlocutor, suggests that lyric poets struggle for sovereignty, for mastery over the subjects that engross them, those of this book allow their “topic” to master them, so that they might be unmade and remade through a virtual life of love.

Topic: Poetry Analysis and Criticism
Subfield: Literature and Literary Theory
Field: Arts and Humanities
Domain: Social Sciences
NON-OBSERVANCE OF MAXIMS IN ASK.FM SOCIAL Q&amp;A WEBSITE

This paper entitled “Non-Observance of Maxims in Ask.fm Social Q&amp;A Website” investigates the types of maxims and non-observance of maxims which are broken on purpose by Ask.fm users. It also examines some possible reasons for breaking the maxims. By employing Grice’s (1975) cooperative principle, this qualitative study examines one hundred interactions of Ask.fm users. The findings reveal that maxim of quantity, relation and manner are types of maxims which are not obeyed by the users. In addition, the types of non-observance of maxims identified in this study are flouting and opting out. Finally, reasons for breaking maxims are due to the intention to create jokes, to please others and to avoid cyberbullying. Overall, the findings suggest that by performing non-observance intentionally, it does not necessarily lead to communication breakdown. In fact, it made the conversation in Ask.fm more interesting, relax, and lively.&#13;\nKeywords: Grice’s Cooperative Principle, Non-observance of maxims, social media, website, Ask.fm&#13;\nPenelitian yang berjudul “Pelanggaran Maksim di Situs Tanya-jawab Ask.fm” mengkaji beberapa tipe maksim dan tipe pelanggaran maksim yang sengaja dilanggar oleh pengguna Ask.fm. Penelitian ini juga membahas beberapa penyebab yang mempengaruhi para pengguna Ask.fm untuk melanggar maksim tersebut. Dengan mengacu kepada teori prinsip kooperatif Grice (1975), penelitian kualitatif ini meneliti seratus interaksi dari pengguna Ask.fm. Hasil dari penelitian ini menunjukan bahwa para pengguna melanggar tiga tipe maksim, yaitu maksim quantity, relation, dan manner. Pelanggaran maksim yang dilakukan oleh pengguna situs dalam studi ini masuk ke dalam kategori flouting dan opting out. Sebagai tambahan, penyebab mengapa para pengguna Ask.fm melakukan pelanggaran maksim adalah untuk menyampaikan lelucon, menghibur orang lain, dan menghindari cyberbullying. Secara keseluruhan, hasil penelitian ini menemukan bahwa dengan mempraktekkan kasus pelanggaran maksim secara sengaja, para pengguna Ask.fm menunjukkan keberhasilan dalam berkomunikasi. Faktanya, pelanggaran maksim di situs Ask.fm dapat membuat komunikasi berjalan menarik, santai, dan lancar. &#13;\nKeywords: Prinsip Kooperatif Grice, pelanggaran maksim, media sosial, situs, Ask.fm

Topic: Magnetic confinement fusion research
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
DEVELOPMENT OF A FLAMEOUT SENSOR FOR RAPID RELIGHT OF TURBO-JET ENGINE

In a program directed to the development, design, and test demonstration of a device for detecting flame-out in a turbo-jet engine, breadboard and prototype devices were delivered to the Naval Air Turbine Test Station, Trenton, New Jersey, for functional test. The test program was delayed by malfunction of the test facility and attendant rescheduling problems. (Author)

Topic: Advanced Combustion Engine Technologies
Subfield: Fluid Flow and Transfer Processes
Field: Chemical Engineering
Domain: Physical Sciences
Sustainable Production of Slow Release Fertilizers for Eco-Nutrient Delivery to Soil Microbial Communities in Nutrient Deficient soils

There is a growing need to develop a natural-based slow-release fertilizer for sustained nutrient delivery as a result of the challenges associated with the direct application of chemical fertilizers. In this study, two low crop residues, cassava mesocarp CM and coconut coir dust CD were employed in the formulation and production of slow-release fertilizers (SLR). The proximate and mineral content analysis revealed an appreciable quantity of micronutrients and other soil stabilizers in the crop residues. Super absorbent polymers produced from both crop residues (CM-SAP and CCD-SAP) revealed water absorption positive correlation values as 0.9842and 0.9859 and final dry weight values ranging from 2.66–2.99g and 2.20–2.28g, respectively. NPK garden fertilizer (20:10:10) was encapsulated in to each SAP to create the slow- release properties of the products branded casmes and coco dust. The conductivity analyses performed on the SLR formulations showed a steady release of the nutrient content in to the liquid medium which ranged from 10µs/cm at 30mins to 290µs/ cm at 160mins for casmes while cocodust had a final value of 110µs/cm. Both formulations were applied as biostimulants alongside other nutrient regimens and it was observed that the products supported the growth of active bacteria population competing favourably with other biostimulants.

Topic: Polymer-Based Agricultural Enhancements
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
DISCRETE-TIME VARIABLE STRUCTURE CONTROLLER FOR AIRCRAFT FLIGHT ANGLE TRACKING

Summary The paper presents the longitudinal, short-period aircraft dynamics and its application on the climb angle tracking. For the aircraft flight angle tracking the stable system centre technique is developed for controlling the output in a discrete-time non-minimum phase causal system using the sliding mode control. The developed discrete-time stable system centre technique transforms the output tracking problem to a corresponding state variable tracking problem by asymptotically identifying the ideal internal dynamics for the unstable internal states of a discrete-time system. A numerical simulation example is given to show the effectiveness of the method.

Topic: Adaptive Control of Nonlinear Systems
Subfield: Control and Systems Engineering
Field: Engineering
Domain: Physical Sciences
Islam and the Retrenchment of Turkish Conservatism

Abstract Islamist mobilization in Turkey has evolved into an Islamic conservatism that parallels mainstream Western (especially American) conservatism. After the turn of the century, interpretations of Islam that focus on authority, conformity and national strength have marginalized understandings of Islam that uphold liberties and plurality (“post-Islamism”), just like they have sidelined strict adherence to the scriptures and opposition to secularism (old style Islamism). Moreover, Islamic discourse on social issues has shifted from an emphasis on communal responsibility to a eulogy of individual responsibility. In line with these transformations, old religious foes (Islamists on the one hand and anti-Islamist, conservative Islamic communities such as the Gülen community on the other) have becomes allies.

Topic: Turkey's Politics and Society
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
Features and specifics of the main threats of the enterprises of power industry of the North Caucasian region

Power industry has become a vital component of the modern Russian economy and electric power plants can be found in each federal district of this country, which makes power industry of strategic importance for ensuring economic security of the Russian Federation. Similar to other industries, electric power sector has its specific features and a set of related specific risks and safety hazards. The authors argue that threats, inherent in power plants, must be examined for identifying urgent issues and ways to cope with threats, caused by fuel resources shortages, drawbacks in power supply of the North-Caucasian Region and challenges of peaking capacitances seasonality at water-power plants.

Topic: Arctic and Russian Policy Studies
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Kinematic analysis of a two different shooting technique in handball

Rezultati usporedne kinematicke analiza skok suta s vanjske pozicije izvedenih od dva elitna svjetska rukometasa, pokazali su postojanje znatnih razlika među njima. Skok prvog ispitanika bio je nesto niži a izbacaj lopte bio je u maksimumu trajektorije. Ovakav nacin skok suta upucuje da se radi o vrsti direktnog suta, cija je najveca prednost kratkoca vremena sto je proteklo od odraza do izbacaja lopte. Skok drugog ispitanika bio je izuzetno visok, bas kao i visina izbacaja lopte. Međutim, cinjenica da je izbacaj uslijedio u silaznoj fazi trajektorije težista, kao i relativno dugo vrijeme proteklo od odraza do izbacaja, upucuju da se ovaj skok sut može uvrstiti u skupinu suteva sa zadrskom. Prednost ovakvog nacina sutiranja svakako je velika visina izbacaja, te dovoljno vremena za fintiranje igraca iz obrambenog bloka i golmana. S obzirom da i jedan i drugi nacin skok suta ima svoje prednosti i nedostatke njihova primjena prvenstveno ce zavisiti od tehnicko taktickih sitacija igre, te od fizicke pripremljenosti igraca.

Topic: Sports Performance and Training
Subfield: Orthopedics and Sports Medicine
Field: Medicine
Domain: Health Sciences
Multiple Antenna Enhancements for a High Rate CDMA Packet Data System

A High Data Rate (HDR) system has been proposed for providing downlink wireless packet service by using a channel-aware scheduling algorithm to transmit to users in a time-division multiplexed manner. In this paper, we propose using multiple antennas at the transmitter and/or at the receiver to improve performance of an HDR system. We consider the design tradeoffs between scheduling and multi-antenna transmission/detection strategies and investigate the average Shannon capacity throughput as a function of the number of antennas assuming ideal channel estimates and rate feedback. The highest capacities are achieved using multiple antennas at both the transmitter and receiver. For such systems, the best performance is achieved using a multi-input multi-output capacity-achieving transmission scheme such as BLAST (Bell Labs Layered Space-Time) in which the transmitted signal is coded in space and time, and the receive antennas are used to resolve the spatial interference. In the second part of the paper, we discuss practical transmitter and receiver architectures using BLAST for approaching the theoretical gains promised by the capacity analysis. Because the terminal receivers will be portable devices with limited computational and battery power, we perform a computational complexity analysis of the receiver and make high-level assessments on its feasibility. We conclude that the overall computational requirements are within the reach of current hardware technology.

Topic: Advanced Wireless Communication Techniques
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
P0655 / #2074: EMERGENCE OF BURKHOLDERIA CEPACIA COMPLEX SEPSIS AMONG NEONATES: A RETROSPECTIVE COHORT STUDY

Aims & Objectives: Burkholderia cepacia complex (BCC) is emerging as an important causative agent of neonatal sepsis however, there is dearth of literature on same. We aim to determine the incidence, clinical features, antibiotic susceptibility pattern and outcome of culture proven BCC sepsis among neonates. Methods: It was a retrospective study and the data of all neonates admitted in Neonatal Intensive Care Unit (NICU) from July 2016 to June 2020 with BCC sepsis was retrieved from computerized database and analyzed. Results: Of the total 942 NICU admissions, the incidence of total and culture positive sepsis was 33.5% (316/942) and 12% (113/942) respectively. There were a total of 172 isolates with 124 (72%) being gram negative bacilli (GNB). Among GNBs, Klebsiella (n=36; 29%), Acinetobacter (n=27; 22%) and Burkholderia (n=17; 14%) were the predominant isolates. Thirteen neonates had these 17 isolates and out of these, 12 (70%) isolates were from VLBW infants. Respiratory deterioration, feed intolerance and recurrent apneas were the major presenting features. Hemodynamic instability was observed in 4 cases. Meningitis was diagnosed in 7 (41%) cases. 82% of neonates had invasive lines at the time of sepsis and 65% were invasively ventilated. None of the isolate was resistant to cotrimoxazole, 14 isolates were resistant to piperacillin-tazobactam, 9 to levofloxacin, and 3 each to Meropenem and ceftazidime. 11 (65%) isolates were multi drug-resistant (MDR). The case fatality rate was similar to non-BCC isolates [31% versus 30%; p=0.95]. Conclusions: Burkholderia cepacia complex sepsis has emerged as a third largest GNB isolate in our cohort.

Topic: Neonatal and Maternal Infections
Subfield: Public Health, Environmental and Occupational Health
Field: Medicine
Domain: Health Sciences
INCIDENCE OF SLEEP LOSS AND WAKEFULNESS DEGRADATION ON A U.S. COAST GUARD CUTTER UNDER EXEMPLAR CREWING LIMITS.

Abstract : The central objective of this study was to determine whether crew members are experiencing unacceptable fatigue levels while sailing under Exemplar crew reductions. This study was conducted aboard the CG Cutter MUNRO (WHEC-378 foot) during a patrol from Tokyo, Japan to Pearl Harbor, Hawaii. Daily evaluations of alertness and of the stability of the sleep/wake cycle were used to characterize fatigue levels throughout 30 consecutive days on patrol. Fourteen crew members participated in wakefulness maintenance tests consisting of the observation of the latency to sleep onset while volunteers attempted to maintain wakefulness. Nine out of 14 participants failed to maintain wakefulness in 57 to 100 percent of the tests. Forty-three volunteers participated in daily sleep evaluations by wearing wrist worn activity monitors 24 hours per day. Activity monitor data were used to document daily sleep onset times, wake up times, and the stability of the sleep/wake cycle throughout the 30 day evaluation. Over sixty percent of all scored sleep profiles exhibited severe disruptions of sleep patterns. Correlation analysis confirmed that participants experiencing frequent disruptions of the sleep/wake cycle also suffered reductions of sleep below six hours and a high incidence of failure to maintain wakefulness above six minutes, signifying reduced alertness. Watch schedules requiring frequent rotations from daytime to nighttime and early morning duty hours contributed to the consistent disruption of sleep/wake cycles. The combination of current watch schedules, reduced personnel, and high operational tempo are expected to exacerbate the fatigue symptoms documented in this patrol. To minimize sleep/wake cycle disruptions, it is recommended that the frequency of rotation from daytime to night and early morning duty hours be reduced.

Topic: Occupational Health and Performance
Subfield: Occupational Therapy
Field: Health Professions
Domain: Health Sciences
ESG-persistence in Socially Responsible Mutual Funds

This paper analyzes the persistence of environmental, social, and governance (ESG)-scores in socially responsible (SR) mutual funds. ESG-scores can be used as a measure for the level of social responsibility of an SR mutual fund. It is shown that ESG-scores persist for approximately two years. However, the persistence of the ESG-scores is terminated after approximately three years. This implies that value-driven investors of SR mutual funds who seek high-ESG investments cannot rely upon a long-term continuation of high ESG-scores and thus need to rebalance their portfolio from time to time. The lack of long-term persistence in the ESG-scores is caused by changes in the holdings of the SR mutual funds.

Topic: Financial Markets and Investment Strategies
Subfield: Finance
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Constitutionalism in Colonial Context: The Palestinian Basic Law as a Metaphoric Representation of Palestinian Politics (1993–2007)

The military control of Palestinian borders aiming to supervise the movement of people, commodities, capital and explosives has been the major question in the construction of the Israeli domination regime in the West Bank (WB) and Gaza Strip (GS) since June 1967. Despite the dominant security discourse and legitimization, I will argue here that the economic interests have been of dominant importance. The pattern of domination established in 1967—a captive market incorrectly called a "customs union"—has suffered significant changes since its formal Palestinian legitimization by the "Paris protocol" on May 1994, and since then it has deteriorated into a structurally unstable regime that I have proposed to call a "strangling envelope" (Grinberg 2007a).

Topic: Jewish and Middle Eastern Studies
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Aminoacylation of Nucleosides with FMOC Amino Acid Fluorides<sup>1</sup>

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTAminoacylation of Nucleosides with FMOC Amino Acid Fluorides1J. S. Oliver and A. OyelereView Author Information Department of Chemistry, Brown University, Providence, Rhode Island 02912 Cite this: J. Org. Chem. 1996, 61, 12, 4168–4171Publication Date (Web):June 14, 1996Publication History Received26 January 1996Published online14 June 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/jo9601674https://doi.org/10.1021/jo9601674brief-reportACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views595Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Anions,Monomers,Nucleic acids,Peptides and proteins,Reaction products Get e-Alerts

Topic: Advanced biosensing and bioanalysis techniques
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Design and algorithm research of a GNSS/FOG-SINS integrated navigation system for unmanned vehicles

According to the application requirements of autonomous navigation for unmanned vehicles which mainly used for forest exploration and border patrols, this paper designs a cost effective GNSS/SINS integrated system based on the fiber optic gyro (FOG). After that, the alignment method of SINS and the integrated navigation algorithm are also improved. By fusing the valid data of GNSS/FOG-SINS with Kalman filter, the error of inertial devices can be corrected and the high-precision inertial navigation results are used to locate by the satellite navigation system. At the end of this paper, the simulation and the vehicle field test are done, from which we can see that the tested accuracy can meet the practical precision requirement of the integrated navigation system when the satellite signal is blocked in the complex terrain environment for one minute.

Topic: Inertial Sensor and Navigation
Subfield: Aerospace Engineering
Field: Engineering
Domain: Physical Sciences