jimnoneill/paper-to-field-training huggingface dataset:
ANTIBACTERIAL ACTIVITY TEST OF DIPHENYLTIN(IV) DIBENZOATE AND TRIPHENYLTIN(IV) BENZOATE COMPOUNDS AGAINST BACILLUS SUBSTILIS AND PSEUDOMONAS AERUGINOSA

The antibacterial activity test of 2 organotin(IV) compounds, diphenyltin(IV) dibenzoate (2)
and triphenyltin(IV) benzoate (4) which were prepared by the reaction of diphenyltin(IV) dihydroxide
and triphenyltin(IV) hydroxide with benzoic acid has been pereformed. These compounds were
characterized by 1H and 13C NMR, IR, UV-Vis spectroscopies and also based on the microanalytical
data. The results of antibacterial activity by diffusion method against Pseudomonas aeruginosa and Bacillus
subtilis showed that both compounds werre active at concentration of 200 ppm, which are about 3.89x
10-4 M for 2 and 4.47x10-4 M for 4, while the chloramphenicol, as control postive, at the same
concentration 200 ppm ((6.1894 x 10-4 M), gave inhibition with halozone was bigger. This result indicated
that both compounds have potential to be used as antibacterial substances.

Topic: Organometallic Compounds Synthesis and Characterization
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Small bowel neuroendocrine tumors: A critical analysis of diagnostic work‐up and operative approach

Background Small bowel neuroendocrine tumors (SB‐NETs) are often small, multifocal, difficult to localize preoperatively, and can be overlooked during operative exploration. The optimal work‐up and operative approach is unknown. Methods Patients who underwent resection of SB‐NETs at a single‐institution from 2000 to 2014 were included. Primary aim was to describe the diagnostic work‐up and compare minimally invasive (MIS) to open resection. Results Ninety‐three patients underwent resection for SB‐NETs. About 71% were symptomatic and on average underwent three diagnostic tests: 45% had octreoscans (85% diagnostic yield); 11% had SB‐enteroscopy (10% yield); 19% had capsule endoscopy (83% yield, but identified the correct tumor number in only 21%). About 27 pts underwent MIS versus 66 open. MIS pts were younger (56 vs. 61 yrs; P = 0.035), and less likely to have obstruction (4% vs. 24%; P = 0.019) and metastases (19% vs. 44%; P = 0.038). Compared to open, MIS had smaller (1.7 vs. 2.4 cm; P = 0.03) and fewer tumors resected (2 vs. 5; P = 0.049), but similar LN yield (13 vs. 12; P = 0.7). In non‐metastatic, curative‐intent resections, MIS still resected fewer tumors compared to open (1.5 vs. 4; P = 0.034). Conclusion Capsule endoscopy may be better than small bowel enteroscopy at identifying occult SB‐NETs, but may underestimate tumor burden. While MIS may be appropriate in select patients, recognizing the limitations of preoperative evaluation is critical for these tumors, as heightened operative vigilance is often required. J. Surg. Oncol. 2016;114:671–676 . © 2016 Wiley Periodicals, Inc.

Topic: Neuroendocrine Tumor Research Advances
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
THE EFFECTS OF HYPERINFLATION ON FINANCIAL REPORTING AND AUDIT PRACTICES: EVIDENCE FROM TÜRKİYE

The purpose of this paper is to reveal the impact and reflections of a hyperinflationary economy, thus hyperinflationary accounting on annual financial reports and independent auditor’s reports in Turkey for the year 2023 regarding IAS 29 Financial Reporting in Hyperinflationary Economies, and International Standard on Auditing (ISA) 701-Communicating Key Audit Matters in the Independent Auditor’s Report &amp; (ISA) 706- Emphasis of Matter Paragraphs in the Independent Auditor’s Report. This study concerns a relatively emerging topic and an additional specific area for which there are a few studies peculiar to each country’s economy. The empirical findings of this study are significant in that they provide a complete map from a broader research perspective. The study adds to the literature by providing valuable insights and content about the matter of hyperinflation which is an ongoing problem in the long term as regards financial reporting and independent auditing. Moreover, it raises awareness about the reporting challenges of hyperinflation for the prospective hyperinflationist periods that might occur in the foreseeable future.

Topic: Auditing, Earnings Management, Governance
Subfield: Accounting
Field: Business, Management and Accounting
Domain: Social Sciences
Abstract 3582: In vitro pharmacological studies of water soluble garlic extract (WSGE) in the management of acute promyelocytic leukemia (APL)

Abstract Garlic (allium sativum) is one of the oldest cultivated plants, used in spices, food, and herbal medicine for over 4000 years. The therapeutic efficacy of garlic has a wide variety of ailments, including cardiovascular, cancer, hepatic and microbial infections. Although the therapeutic efficacy of garlic in the prevention of cancer and other diseases has received increasing attention in recent years, little is known about its mechanism for therapeutic action. In this research, we hypothesize that the pharmacological effect of garlic may be mediated through oxidative stress, DNA damage, modulation of annexin-5 and caspase-3 in human leukemia (HL-60) cells. To test this hypothesis, HL-60 cells were treated with various doses of water soluble garlic extract (WSGE) for 12 h. Cell survival was determined by MTT-assay. The extent of oxidative cell/tissue damage was determined by measuring the level of malonaldiahyde (MDA) concentrations. Cell apoptosis was measured by flow cytometry using annexin V and caspase-3 kits, respectively. MTT assay indicated a strong dose-response relationship with regard to the cytotoxic efficacy of WSGE in HL-60 cells. There was a slight increase in MDA concentrations in WSGE-treated cells compared to the control, but this was not statistically significant (P &amp;gt; 0.05) probably due to the antioxidant property of garlic. WSGE-induced apoptosis was characterized by a significant (P &amp;lt; 0.05) increase in the percentages of annexin-5 and caspase-3 positive cells. In summary, the pharmacotherapy of WSGE may be associated through induction of moderate toxicity, induction of DNA damage, phosphatidylserine externalization and caspase-3 activation characteristic of apoptosis. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 2010 Apr 17-21; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2010;70(8 Suppl):Abstract nr 3582.

Topic: Garlic and Onion Studies
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Cytoskeletal Functions During <i>Drosophila</i> Oogenesis

Organismal morphogenesis is driven by a complex series of developmentally coordinated changes in cell shape, size, and number. These changes in cell morphology are in turn dependent on alterations in basic cytoarchitecture. Elucidating the mechanisms of development thus requires an understanding of the cytoskeletal elements that organize the cytoplasm of differentiating cells. Drosophila oogenesis has emerged as a versatile system for the study of cytoskeletal function during development. A series of highly coordinated changes in cytoskeletal organization are required to produce a mature Drosophila oocyte, and these cytoskeletal transformations are amenable to a variety of experimental approaches. Genetic, molecular, and cytological studies have shed light on the specific functions of the cytoskeleton during oogenesis. The results of these studies are reviewed here, and their mechanistic implications are considered.

Topic: Cellular Mechanics and Interactions
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Antinociceptive activity of Hypericum caprifoliatum and Hypericum polyanthemum (Guttiferae)

The aim of the present study was to assess the analgesic activity of the aerial parts of two Hypericum species native to Southern Brazil, H. caprifoliatum and H. polyanthemum. The antinociceptive effect of the H. polyanthemum cyclohexane extract (POL; 180 mg/kg) and of the H. caprifoliatum methanol (MET) and cyclohexane (CH) extracts (90 mg/kg) was evaluated in the hot-plate (ip and po) and writhing (po) tests using male Swiss CF1 mice weighing 22-27 g (N = 10 per group). All extracts displayed antinociceptive effects in the hot-plate test (MET ip = 48%, MET po = 39%, CH ip = 27%, CH po = 50%, POL ip = 74%, and POL po = 49% compared to control). Pretreatment with naloxone (2.5 mg/kg, sc) abolished the effects of CH and POL, and partially prevented the analgesia induced by MET administered by the ip (but not by the po) route. POL and CH (po) significantly reduced the number of writhes induced by acetic acid, while MET was ineffective in this regard. We conclude that the antinociceptive effects of the H. caprifoliatum (CH) and H. polyanthemum (POL) hexane extracts seem to be mediated by the opioid system. Moreover, the antinociceptive activity of the H. caprifoliatum MET extract seems to depend on at least two chemical substances (or groups of substances) with distinct pharmacokinetic profiles and mechanisms of action. Only the naloxone-insensitive component of MET activity showed good bioavailability following oral administration.

Topic: Natural Compound Pharmacology Studies
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Cone-shaped Inwall Capillary based Microcavity Aimed for Temperature and Refractive Index Sensing

A cone-shaped capillary based microcavity aimed for the temperature and refractive index sensing are proposed, modeled and demonstrated, while the femtosecond laser micromachining method successfully enhances the Q factor.

Topic: Photonic and Optical Devices
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Research on Patent Protection of Business Model under the Background of Internet

"Internet +" is a disruptive technological innovation that brings unlimited possibilities for business model innovation. However, the lack of the patent protection system of the business model has hindered the innovation and development of the business model to a certain extent. From the perspective of the Internet + business model, this article briefly describes the current status and shortcomings of the protection of business model patents in China, and puts forward some thoughts and suggestions on establishing an Internet + business model to form a business model patent protection system.

Topic: Entrepreneurship Studies and Influences
Subfield: Management of Technology and Innovation
Field: Business, Management and Accounting
Domain: Social Sciences
Synchronization of thermal-carrier oscillations in coupled silicon microcavities

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text G. O. Luiz, T. P. M. Alegre, and G. S. Wiederhecker, "Synchronization of thermal-carrier oscillations in coupled silicon microcavities," in Conference on Lasers and Electro-Optics, OSA Technical Digest (online) (Optica Publishing Group, 2017), paper JTh2A.104. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article

Topic: Photonic and Optical Devices
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
LENGTH-WEIGHT RELATIONSHIPS FOR 14 FISH SPECIES OF NAPO RIVER BASIN, PERUVIAN AMAZON

This work presents the length-weight relationships of 14 species of fish of the Napo River basin. Fish collections were carried out between 2012 and 2014, using gill nets and seine. A total of 1896 specimens, belonging to 14 species and five orders were analyzed. The allometric coefficient b ranged from 2.69 to 3.78. A new record of length-weight relationship is presented for Curimata cisandina (Allen, 1942). The comparisons with other Amazonian studies indicated differences in the parameters a and b of LWR with this study for the species Triportheus angulatus (Spix &amp; Agassiz, 1829), Mylossoma duriventre (Cuvier, 1818), Roeboides myersii Gill, 1870 and Pellona castenaena Valenciennes, 1847 and only parameter b for Psectrogaster amazonica. The results presented in this work contribute to a better knowledge of fish resources in the region of the Peruvian Amazon, especially in the Napo River basin.

Topic: Fish Biology and Ecology Studies
Subfield: Aquatic Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Some Arguments Against Analyzing Client Change Graphically

Although single‐subject research techniques are relevant and valuable to counselors, analyzing change by graphs alone is open to major sources of error. The author discusses these sources and explores the issues of serial dependency, unreliability of graphs, interjudge disagreement on graphed data, and the use of a more reliable statistical procedure (the time‐series statistic) with relevance to the counselor in the field.

Topic: Cognitive and psychological constructs research
Subfield: Social Psychology
Field: Psychology
Domain: Social Sciences
Emergence of Coccoloba gigantifolia Melo, Cid Ferreira &amp; Gribel seedlings as a function of raceme and fruit maturation

Abstract: Coccoloba gigantifolia fruits show uneven maturation within each raceme, which can affect the quality of the seeds. This study aimed to characterize racemes, fruits, and seeds, after harvest, and evaluate the physiological performance of the seeds as a function of the fruit maturation stage. After characterization, two experiments were set up. In the first, a completely randomized design was used, in a 4 (racemes) x 4 (fruit maturation stages: green, half-green, red, and purple) factorial scheme, with 4 replications. In the second, a randomized block design was adopted, in a 4 (fruit maturation stages) x 2 (with and without seed drying) factorial scheme, with 4 replications. Fruit maturation occurs progressively within each raceme, with fruits from completely green to completely purple in color existing at the same time. In propagation, preference should be given to harvesting racemes with a greater number of fruits in the half-green, red, and purple stages, since seeds from green fruits have low physiological quality. In addition to the variation in emergence as a function of fruit maturation, the seeds of the different racemes also showed different behaviors, which seems to be associated with different levels of seed dormancy.

Topic: Growth and nutrition in plants
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Post-Pandemic Office Work: Perceived Challenges and Opportunities for a Sustainable Work Environment

The widespread adoption of remote and hybrid work due to COVID-19 calls for studies that explore the ramifications of these scenarios for office workers from an occupational health and wellbeing perspective. This paper aims to identify the needs and challenges in remote and hybrid work and the potential for a sustainable future work environment. Data collection involved two qualitative studies with a total of 53 participants, who represented employees, staff managers, and service/facility providers at three Swedish public service organisations (primarily healthcare and infrastructure administration). The results describe opportunities and challenges with the adoption of remote and hybrid work from individual, group, and leadership perspectives. The main benefits of remote work were increased flexibility, autonomy, work-life balance and individual performance, while major challenges were social aspects such as lost comradery and isolation. Hybrid work was perceived to provide the best of both worlds of remote and office work, given that employees and managers develop new skills and competencies to adjust to new ways of working. To achieve the expected individual and organisational benefits of hybrid work, employers are expected to provide support and flexibility and re-design the physical and digital workplaces to fit the new and diverse needs of employees.

Topic: Facilities and Workplace Management
Subfield: Social Psychology
Field: Psychology
Domain: Social Sciences
Progress In Coherent Optical Fibre Transmission Techniques In The United Kingdom

The initial reason for investigating coherent optical fibre transmission techniques was to determine if the predicted improvements in receiver sensitivity of between 10 to 20 dB over direct detection (1,2) could be achieved in a laboratory experiment. There had been several areas of doubt about the practicability of coherent detection, in particular the spectral properties of semiconductor laser sources, the polarisation characteristics of the fibre transmission medium, the increased complexity of a coherent transmission system and the extensive engineering development that is necessary. Once the practical problems have been reconciled a future for coherent transmission could be forseen, not just for point-to-point long haul telecommunications, but also for wideband signal distribution in local networks. For this second application the extra sensitivity of coherent detection would largely overcome optical path splitting losses and the selectivity of coherent detection could allow many thousands of channels to be frequency multiplexed with a spacing not attainable by other techniques.

Topic: Optical Network Technologies
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Proto‐oncoprotein Zbtb7c and <i>SIRT1</i> repression: implications in high‐fat diet and age‐dependent obesity

Zbtb7c is a proto‐oncoprotein that control cell cycle, and glucose, glutamate, and lipid metabolism. Zbtb7c expression is increased in the liver and white adipose tissues of aging or high‐fat diet‐fed mice. The knockout or knockdown of the Zbtb7c gene expression decreases adipose tissues in aging mice and inhibits adipocyte differentiation in 3T3‐L1 cells. We found that SIRT1 expression is derepressed in various tissues of Zbtb7c KO mice, and Zbtb7c is a potent transcription repressor of SIRT1. Mechanistically, Zbtb7c interacted with p53 and bound to the proximal promoter p53REs to repress the SIRT1 gene, in which p53RE2 is particularly critical. Zbtb7c made p53 interact with the corepressor mSin3A‐HADC1 complex at the p53RE. By repressing the SIRT1 gene, Zbtb7c increased the acetylation of Pgc‐1a and Pparg, which resulted in repression or activation of Pgc‐1a or Pparg target genes of lipid metabolism. Our study provided a molecular target that can overexpress SIRT1 protein in the liver, pancreas, adipose tissues, which can be beneficial in the treatment of diabetes, obesity, longevity, etc.

Topic: Sirtuins and Resveratrol in Medicine
Subfield: Geriatrics and Gerontology
Field: Medicine
Domain: Health Sciences
Aging and Mitochondrial DNA

According to the mitochondrial theory of aging, accrual of mutations in mitochondrial DNA (mtDNA) plays the paramount function in the cellular pathology of aging and in development of age-related degenerative ailments. Reactive oxygen species (ROS), which are byproducts of oxidative phosphorylation (OX-PHOS) in aerobic (mitochondrial) respiration, cause oxidative stress-induced damage to mtDNA. This damaged DNA, whose normal role is to encode proteins many of which are players in the electron transport chain (ETC), now codes for defective proteins. Such faulty proteins lead to a considerable impairment in the efficacy of ETC, thereby generating more ROS, which cause further damage to mtDNA in turn, leading to further defects in proteins, aggravated ETC dysfunction, and even more ROS. Hence, a ‘vicious cycle’ propagates that ultimately directs tissue cells towards structural and functional decline, or in other words, degeneration and aging. However, in spite of a wide acceptance of this theory, there have simultaneously been a considerable number of criticisms against it. This review is aimed at discussing the paradigm of aging and degenerative diseases in light of the mitochondrial paraphernalia, with reference to the evidences in support as well as in antagonism to the mitochondrial theory of aging.Keywords: Aging; Degenerative diseases; mtDNA mutations; ROS; Cell death.© 2011 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.doi:10.3329/jsr.v3i1.5078 J. Sci. Res. 3 (1), 176-186 (2011)

Topic: Mitochondrial Function and Pathology
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
The Experience of a Clinical Psychologiest

Journal Article The Experience of a Clinical Psychologiest Get access MEXTAL HYGIENE, two years' experience of a clinical psychologist. By Lillien J. Martin, Pp. 89, Price $1.40. Baltimore, Warwick and York, 1920. P.P P.P Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Heredity, Volume 12, Issue 5, May 1921, Page 236, https://doi.org/10.1093/oxfordjournals.jhered.a102095 Published: 01 May 1921

Topic: Academic and Historical Perspectives in Psychology
Subfield: General Psychology
Field: Psychology
Domain: Social Sciences
Legal Construction of International Business Contracts as an Instrument for Strengthening Banana Cracker Exports and Ogan Banana Supply Chain Management in Lumajang Regency

Today's entrepreneurs prioritize international trade as an important goal in business development, which leads to the formation of international business contracts, but not all entrepreneurs understand the various regulations related to international business contracts, dispute resolution in the event of a dispute, and legal certainty in the event of force majeure. In addition, this study also wants to analyze the provisions for the use of Indonesian in agreements based on Law of the Republic of Indonesia Number 24 of 2009 concerning the Flag, Language, and National Emblem, as well as the National Anthem, with an analytical knife using the principle of freedom of contact. This research related to international business contracts was inspired by the desires of home industry entrepreneurs in Nogosari Village, Rowokangkung District, Lumajang Regency, who produce "banana crackers" and want to spread their wings into the world of international trade. In addition to understanding the various rules of international business contracts, banana crackers entrepreneurs also face the problem of difficulty in obtaining organic banana raw materials. Fruits have a high water content so they are easily damaged and have a short shelf life. Bananas are a type of fruit that is easily damaged, so there must be a solution, namely producing banana products, one of which is banana crackers and analyzing the management of the Supply Chain....

Topic: Legal Studies and Policies
Subfield: Law
Field: Social Sciences
Domain: Social Sciences
Supplementary Figure 9 from Cooperativity of E-cadherin and Smad4 Loss to Promote Diffuse-Type Gastric Adenocarcinoma and Metastasis

&lt;p&gt;PDF - 81K, Monolayer growth rate of primary cells after knockdown of beta-catenin.&lt;/p&gt;

Topic: Kruppel-like factors research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Self-regulation Strategies and Vocabulary Size of EFL Turkish University Students

The present study attempted to investigate the relationship between Turkish EFL learners⿿ self-regulated learning components and vocabulary knowledge. The study examined the relationship between the participants⿿ proficiency level and vocabulary size. To fulfill this objective, a 150-item Schmitt vocabulary test administered to a sample of 149 students at Hacettepe University and 30 English Language and Literature students at Bülent Ecevit University. The Self- Regulation Questionnaire was administered to the same participants after they answered the vocabulary test. The results revealed that there is a strong positive correlation between high levels of self-regulation and high vocabulary size.

Topic: Innovative Teaching and Learning Methods
Subfield: Developmental and Educational Psychology
Field: Psychology
Domain: Social Sciences