jimnoneill/paper-to-field-training huggingface dataset:
ASSESSMENT IN THE MERDEKA CURRICULUM: HOW ARE THE TEACHERS' PERSPECTIVES ON IT?

Assessment is a step to measure students’ learning outcomes. This paper discusses the teachers’ perception and understanding of how to carry out assessments in the Merdeka Curriculum. This paper also uses a qualitative descriptive survey research method with four stages; preparation, data collection, data analysis, and conclusions. Data collection techniques are carried out through interviews. The samples of the research are teachers from Penggerak School throughout Riau Province with a total population of 23 teachers. The data obtained are analyzed using descriptive statistical techniques. The results indicate that the implementation of the assessment in the Merdeka Curriculum, which consisted of diagnostic, formative, and summative assessments, is conducted by the teacher after the learning process is completed. Students’ learning outcomes are obtained from their knowledge, attitudes, and skills during learning activities. The student’s learning outcomes are presented in a school report based on the Merdeka Curriculum school report application. Thus, the teachers overall understand and have conducted the assessments that are required in the Merdeka Curriculum.

Topic: Educational Curriculum and Learning Methods
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
[Surgical treatment of Morel-Lavallée lesion with perineal lacerations].

The treatments of Morel-Lavallée lesion with perineal lacerations were significantly different from simple close Morel-Lavallée lesion. With high mortality and disability, Morel-Lavallée lesion with perineal lacerations require more challenging treatment protocols among which the most important is the soft tissue management and nutrition. The satisfactory outcomes come from joint efforts of multiple departments.

Topic: Pelvic and Acetabular Injuries
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Plethora of Antibiotics Usage and Evaluation of Carbapenem Prescribing Pattern in Intensive Care Units: A Single-Center Experience of Malaysian Academic Hospital

Excessive antibiotic consumption is still common among critically ill patients admitted to intensive care units (ICU), especially during the coronavirus disease 2019 (COVID-19) period. Moreover, information regarding antimicrobial consumption among ICUs in South-East Asia remains scarce and limited. This study aims to determine antibiotics utilization in ICUs by measuring antibiotics consumption over the past six years (2016–2021) and specifically evaluating carbapenems prescribed in a COVID-19 ICU and a general intensive care unit (GICU) during the second year of the COVID-19 pandemic. (2) Methods: This is a retrospective cross-sectional observational analysis of antibiotics consumption and carbapenems prescriptions. Antibiotic utilization data were estimated using the WHO Defined Daily Doses (DDD). Carbapenems prescription information was extracted from the audits conducted by ward pharmacists. Patients who were prescribed carbapenems during their admission to COVID-19 ICU and GICU were included. Patients who passed away before being reviewed by the pharmacists were excluded. (3) Results: In general, antibiotics consumption increased markedly in the year 2021 when compared to previous years. Majority of carbapenems were prescribed empirically (86.8%). Comparing COVID-19 ICU and GICU, the reasons for empirical carbapenems therapy in COVID-19 ICU was predominantly for therapy escalation (64.7% COVID-19 ICU vs. 34% GICU, p &lt; 0.001), whereas empirical prescription in GICU was for coverage of extended-spectrum beta-lactamases (ESBL) gram-negative bacteria (GNB) (45.3% GICU vs. 22.4% COVID-19 ICU, p = 0.005). Despite microbiological evidence, the empirical carbapenems were continued for a median (interquartile range (IQR)) of seven (5–8) days. This implies the need for a rapid diagnostic assay on direct specimens, together with comprehensive antimicrobial stewardship (AMS) discourse with intensivists to address this issue.

Topic: Antibiotic Use and Resistance
Subfield: Applied Microbiology and Biotechnology
Field: Immunology and Microbiology
Domain: Life Sciences
Effect of low level helium-neon (He-Ne) laser therapy in the prevention & treatment of radiation induced mucositis in head & neck cancer patients.

The low-level He-Ne laser therapy during the radiotherapy treatment was found to be effective in preventing and treating the mucositis in head and neck cancer patients. Further studies need to be done on a larger sample to find the mechanism.

Topic: Laser Applications in Dentistry and Medicine
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Relationship Of Lipids, C-Reactive Protein And Sialic Acid In The Healthy Individuals.

The study showed that serum CRP and Sialic Acid had a significant negative correlation with serum HDL. A significant positive correlation was found between serum Sialic Acid and triglycerides. CRP and Sialic Acid though expensive but are useful predictors of atherosclerotic disease.

Topic: Liver Disease Diagnosis and Treatment
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Lateralization of Brain Lesions Following Extracorporeal Membrane Oxygenation

The cranial ultrasound and computed tomography scan films of 180 patients who underwent extracorporeal membrane oxygenation were reviewed. Sixteen patients were considered to have moderate to severe brain lesions. Of these, 6 were ischemic and 10 were hemorrhagic. Five (83.3%) of the 6 ischemic lesions involved the right side and only 1 ischemic injury occurred on the left. Seven (70%) of the 10 hemorrhagic lesions occurred solely or predominantly on the side opposite the carotid ligation and 3 were found on the same side as the ligation. One patient suffered a right temporal hemorrhage following cannulation of the left common carotid artery. There was no predominance of brain lesions for either side when both hemorrhagic and ischemic lesions were combined. These observations implicate alterations in cerebrovascular hemodynamics accompanying carotid ligation and reperfusion in the path ogenesis of central nervous system lesions associated with the extracorporeal membrane oxygenation procedure. It is suggested that systematic classification of brain lesions associated with extracorporeal membrane oxygenation be made to get a better understanding of their pathology.

Topic: Mechanical Circulatory Support Devices
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Post‐treatment effects of token reinforcement, verbal praise, and self‐monitoring in a residential psychiatric program

Abstract The present study was designed to investigate the effects of token reinforcement, verbal praise, and self‐monitoring on post‐treatment performance of bedroom preparation tasks by adult clients in a residential psychiatric program. Twenty‐four clients were randomly assigned to six experimental conditions (four subjects per condition) as follows: (1) contingent token reinforcement, (2) contingent verbal praise, (3) contingent token reinforcement plus contingent verbal praise, (4) self‐monitoring, (5) self‐monitoring plus contingent token reinforcement, and (6) control. All participants were exposed to a one week initial baseline period, then one week of their experimental condition, and finally, one week of a second baseline period. Research participants who received contingent token reinforcement engaged in bedroom‐area preparation tasks significantly less during the second baseline period of the study than during the initial baseline period. Verbal praise, however, produced a significant increase in performance from Baseline 1 to Baseline 2. The presence of both contingent token reinforcement and verbal praise produced a significant increase in performance during the second baseline period as compared to the control condition. This increase, however, was not found with concomitant token reinforcement and self‐monitoring. Changes in performance from Baseline 1 to Baseline 2 for participants assigned to the token reinforcement plus self‐monitoring condition were not significantly different from those found for participants assigned to the control condition. Implications of these results for clinical settings using token economies are presented.

Topic: Behavioral and Psychological Studies
Subfield: Developmental and Educational Psychology
Field: Psychology
Domain: Social Sciences
ISONIAZID PROPHYLAXIS SIGNIFICANTLY REDUCES THE INCIDENCE OF TUBERCULOSIS IN PATIENTS AFTER RENAL TRANSPLANT

1Division of Nephrology, Tygerberg Hospital and University of Stellenbosch, 2Centre for biostatistical sciences, University of Stellenbosch

Topic: Tuberculosis Research and Epidemiology
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Optimal long-term investment in general insurance

Introduction&#13;\nAn important issue in actuarial theory is to study the ruin probability of an in- surance company when the management has the possibility of investing in the ﬁnancial market. Azcue and Muler(2009) studies the problem of ﬁnding the op- timal dynamic investment strategy which minimizes the ruin probability under inﬁnite time horizon [1]. It is assumed that the ﬁnancial market follows a classic Black-Scholes model consisting of one risk-free asset (bond) and one risky asset (stock). The insurance claims follow ordinary models in general insurance. One problem with the Azcue and Muler solution is that insurance companies do not decide ﬁnancial strategies for inﬁnite time periods. Normally 5 to 15 years will be more than enough. &#13;\nThis thesis tries to ﬁnd optimal dynamic strategies for these more realistic time perspectives. The same model as in Azcue and Muler(2009) will be used. I will solve this problem recursively with the Bellman equation (known as a dynamic programming equation). Dynamic programming breaks the optimization problem into two sub problems, making a initial decision based on the initial capital and making decisions for the rest of the time period where we only have a probability of what the capital will be. &#13;\nThe probability distribution for the balance of an insurance company is difficult to calculate analytically, I will therefore use Monte-Carlo simulations to approximate the probability distribution. One problem is that since we are dealing with a recur- sive method, there can be to many simulations for the computer to handle. Chapter 2 will introduce the models that are used and show a simple exact calculation to a simpliﬁed problem. Chapter 3 will show the ruin probability and the optimal strategy with ﬁxed weights. The theory on dynamic programming, and how we solve our problem with the Bellman equation on the computer are described in chapter 4. The numerical results of the simulations are described and showed in Chapter 5. Finally, in Chapter 6, a summary with some concluding remarks are given. The computer program and discussion of error sources are included in the appendix.

Topic: Insurance, Mortality, Demography, Risk Management
Subfield: Demography
Field: Social Sciences
Domain: Social Sciences
Relativistic theory of few body systems and their electromagnetic interactions

Recent results obtained from the manifestly covariant spectator theory are summarized. A recent unpublished best fit to NN scattering using 13 OBE parameters gives x{sup 2}=2.25 and a triton binding energy of {minus}8.491 MeV. This agreement is possible because of the existence of off-shell coupling of the phenomenological, intermediate range effective scalar exchanges (both isoscalar and isovector). The previously published results for the deuteron form factors are reviewed, and new, preliminary results for electrodisintegration of the deuteron are presented.

Topic: Atomic and Molecular Physics
Subfield: Atomic and Molecular Physics, and Optics
Field: Physics and Astronomy
Domain: Physical Sciences
DEVELOPMENT OF A HYPSOMETER FOR ATMOSPHERIC SOUNDING.

This report describes the development of a descent hypsometer for use at high altitudes in the atmosphere. The basic concept employed is to measure the equilibrium temperature of a boiling liquid and its pure vapor while the latter is in equilibrium with the ambient pressure. ' The ambient pressure is then determined from the known vapor-pressure temperature characteristics of the liquid, or by direct calibration. This sensor can be used in rocketsondes and dropsondes. It is simple, reliable, and can be produced economically even in small quantities. When prepared for production in moderate quantities, the sensor will have a very attractive cost. It is small, light, and has simple sampling requirements. This report describes all the aspects of development, design, and laboratory and environmental tests. Sonde field tests, which were successfully completed, are described in another report. (Author)

Topic: Hermeneutics and Narrative Identity
Subfield: Philosophy
Field: Arts and Humanities
Domain: Social Sciences
Dynamics of the RING Domain from Human TRAF6 by <sup>15</sup>N NMR Spectroscopy: Implications for Biological Function

Activation of transcription factor NF-kappaB requires Lys63-linked polyubiquitination of the E3 ubiquitin ligase TRAF6 via protein-protein interactions mediated by a RING domain. In this study, intra- and intermolecular chemical exchange processes of the TRAF6 RING domain were analyzed by (15)N NMR spectroscopy. Micro- to millisecond time scale motions were assessed through R 1, R 2, NOE, and cross-correlated relaxation measurements, and the kinetics of these motions were quantified with relaxation dispersion. The relaxation experiments indicate that the protein core is rigid, consistent with the functional requirement that RING domains form a binding scaffold for E2 ubiquitin conjugation enzymes. Chemical exchange is observed at the C-terminal end of the main alpha-helix of the RING domain. The C-terminal end of the main alpha-helix from the RING domain is involved in E2-E3 interactions, and modulation of slow motions for this region of the helix may be a general mechanism by which these interactions achieve ubiquitin transfer. Chemical shift mapping indicates that the TRAF6 RING domain does not self-associate in solution. Numerous RING domains are homo- or heterodimeric, and this is thought to be a functional necessity for recruitment of substrates for ubiquitination, or recruitment of multiple E2 enzymes for efficient substrate ubiquitination. However, lack of self-association for the RING domain from TRAF6, and the observation that the intact protein is a trimer, suggests that close association of RING domains within a homodimeric scaffold may not be a fundamental requirement for biological function.

Topic: Ubiquitin and proteasome pathways
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Datumsbeschränkung bei WWW-Suchanfragen - eine untersuchung der möglichkeiten der zeitlichen einschränkung von suchanfragen in den suchmaschinen Google, Teoma und Yahoo

On their advanced search pages search engines usually offer date restricted searches. But there are problems in determining the actual date information of a web page. We investigate date restricted searches on Google, Teoma and Yahoo. We find that these engines perform poorly on this kind of search. We offer some explanation for this and give an outlook on techniques that could help solve the problem.

Topic: Information Retrieval and Search Behavior
Subfield: Information Systems
Field: Computer Science
Domain: Physical Sciences
Purposeful and Occupation-Based Interventions for Chronic Musculoskeletal Pain: A Systematic Review

Abstract Date Presented 4/17/2015 Chronic musculoskeletal pain is a significant issue in the United States. This systematic review provides information regarding the current state of evidence for purposeful and occupation-based interventions in the treatment of chronic musculoskeletal pain.

Topic: Musculoskeletal pain and rehabilitation
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
In vivo studies on hemopoietic stem cells and target cells for Friend virus infection in vitro.

Friend virus replicating target cells have been characterized by in vitro infection of bone marrow cells from DBA/2 mice after multiple injections of hydroxyurea (HU), after bleeding and/or hypertransfusion and after busulfan treatment. The concentration of CFUS, BFUE and CFUE in the cell suspension was correlated with the number of infectious centers (IC) induced after infection. HU treated mice were also infected in vivo. The results demonstrate that there is almost no target cell 4 h after the last of 4 HU injections. The number of IC induced could correlate with the numbers of CFUS in the HU experiment, but this possibility can be rejected based on the busulfan experiments. All results, including those after bleeding and/or hypertransfusion are compatible with a target cell between BFUE and CFUE, as suggested by other in vitro infection methods and also in vivo experiments.

Topic: Virus-based gene therapy research
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Regulation of Glut-4 Expression in Skeletal Muscle cells: The Roles of Nuclear Respiratory Factor-1 and calcium/calmodulin dependent protein Kinase

GLUT4 protein is the major glucose transporter in skeletal muscle and is vital in the maintenance of euglycemia (17; 108). Underexpression of GLUT4 or impairement of its translocation from intracellular compartments to the cell surface, are linked to diminished glucose transport, hyperglycemia and type II diabetes (59; 61; 153). Type II diabetes can be alleviated by increasing GLUT4 expression (223). Previous reports have shown that overexpression of NRF-1 and activation of CaMKII increases GLUT4 expression but the mechanisms involved have not be characterized (10; 173). Therefore, the objective of this thesis was to investigate the molecular mechanisms by which NRF-1 and CaMK II regulate GLUT4 expression in C2C12 myocytes. We engineered C2C12 cells that overexpressed NRF-1 in response to doxycycline (Dox) using a Tet-On gene expression system and assessed the effects of NRF-1 overexpression on: a) MEF2A, GLUT4 and &amp;Icirc;&amp;acute;ALAS proteins by western blot, and b) the binding of NRF-1 to mef2a and &amp;Icirc;&amp;acute;alas genes and MEF2A to the glut4 gene, by chromatin immunoprecipitation assay (ChIP). The importance of MEF2A in NRF-1-induced increase in GLUT4 expression was investigated by silencing MEF2A expression using small interference RNA (siRNA). CaMK II was activated in wild-type C2C12 myocytes using 10 mM caffeine and was inhibited by 25 &amp;Icirc;¼ M KN93. Acetylation of histones in the vicinity of NRF-1 and MEF2A binding sites on the mef2a and glut4 genes, respectively, were assessed by ChIP assay. HDAC5 nuclear export was assessed by immunocytochemistry and mRNA levels by qRT-PCR. Overexpression of NRF-1 resulted in ~3-fold increases in mef2a-bound NRF-1 and glut4 -bound MEF2A at 6 h and 8 h post Dox treatment, respectively. MEF2A and GLUT4 proteins were both increased ~1.6-fold at 6 h and 18 h post Dox treatment. Silencing of MEF2A caused a marked downregulation of GLUT4 expression in NRF-1-overexpressing cells.

Topic: Adipose Tissue and Metabolism
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Antinociceptive local effect of the combination of dexketoprofen trometamol and chlorhexidine gluconate in a formalin test: an additive effect

ABSTRACT A drug delivery system (DDS) with analgesic and antibacterial properties would be desirable for the local control of post-operatory pain and the prevention for surgical site infection (SSI). The objective of the present study was to evaluate the antinociceptive effect of the combination between dexketoprofen trometamol (DXT) and chlorhexidine gluconate (CHX) in the formalin pain model. Different doses of CHX were combined with DXT and were locally administered in rats paw simultaneously with 5% formalin dilution. Flinches were documented and the antinociceptive effect was calculated. The area under the curve of each experimental group were calculated and the % of antinociception were compared. The groups of CHX and DXT showed similar antinociceptive effect. The combination groups (DXT-CHX) showed higher antinociceptive effect that the one obtained with individual molecules. Besides the confirmation of DXT local antinociceptive properties, CHX also showed a positive effect; and an additive effect when combined with DXT.

Topic: Pain Mechanisms and Treatments
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Business and Accounting Ethics in Islam

The present book represents the first serious attempt to explore Islamicbusiness and accounting ethics. After placing their subject in a broad Islamicframework, which they have documented quite ably, they then compare thedistinctive features of Islamic business and accounting principles with Westerntheory and practice. While the book has several strong points and breaks newground in a number of areas, it also lacks clarity and specific authority fromIslamic sources on quite a few points.To begin with, the authors argue quite convincingly that the logical corollaryof prohibiting riba (interest) is the negation of any time value for money.Thus the theory and practice of capital budgeting, which feature in the use discountedcash flow techniques in the West, become redundant. This point,seemingly so obvious to economists, has not found favor with the economicthinking of the Islamic establishment. Rather, many Muslim economists andaccountants have been busy justifying it on one pretext or another. This is thefitst time that somebody has come out with a compelling discussion of this question.The authos have also argued that Islam absolutely forbids the nonrepaymentof a debt. Thus the concept of limited liability, one of mainsprings ofeconomic power in a capitalist society, is not recognized by Islam. However,the related theory of incorporation, the legal mechanism for justifying limitedliability, is found in Islamic societies. Again, such an obvious and sensiblepoint remains unacceptable to Muslim economists. They continue looking forexcuses to accept these ideas, thereby betraying their intellectual poverty.Although the authors do not devote a single chapter to the state’s economicrole in Islam, they discuss this question throughout the book Theyargue for a strong regulatory and framework role for the Islamic state.Gambling and Abdel Karim deal with several other important issues. Forinstance, they argue that the Islamic concept of economic development revolvesaround the development of human resources rather than capital formation,as is the main focus of the popular theory of development in the West.In their discussion of the Islamic concept of shura (consultation) and khilafa(vice-gerency), they also bteak new ground. They opine that these conceptsquestion ...

Topic: Islamic Finance and Banking Studies
Subfield: Accounting
Field: Business, Management and Accounting
Domain: Social Sciences