jimnoneill/paper-to-field-training huggingface dataset:
Adherence of Piliated Haemophilus influenzae Type b to Human Oropharyngeal Cells

Journal Article Adherence of Piliated Haemophilus influenzae Type b to Human Oropharyngeal Cells Get access N. G. Guerina, N. G. Guerina Harvard Medical School, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar S. Langermann, S. Langermann Harvard Medical School, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar H. W. Clegg, H. W. Clegg Harvard Medical School, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar T. W. Kessler, T. W. Kessler Harvard Medical School, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar D. A. Goldmann, D. A. Goldmann Harvard Medical School, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar J. R. Gilsdorf J. R. Gilsdorf University of Minnesota, Minneapolis, Minnesota Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 146, Issue 4, October 1982, Page 564, https://doi.org/10.1093/infdis/146.4.564 Published: 01 October 1982

Topic: Bacterial Infections and Vaccines
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
A C onstraint on Planck-scale M odications to Electrodynam ics w ith C M B polarization data

A bstract. W e show that the Cosm ic M icrowave Background (CM B) polarization data gathered by the BOOM ERanG 2003ightand W M AP providean opportunity to investigate in-vacuo birefringence,ofa type expected in som e quantum pictures ofspace-tim e,with a sensitivity thatextendseven beyond the desired Planck-scale energy. In orderto renderthis constraint m ore transparentwe rely on a wellstudied phenom enologicalm odelofquantum

Topic: Cosmology and Gravitation Theories
Subfield: Astronomy and Astrophysics
Field: Physics and Astronomy
Domain: Physical Sciences
Tuberc Respir Dis 2013;74:82-85

A 62-year-old man with a chronic cough presented with atelectasis of the left upper lobe on chest X-ray. Chest computed tomography showed an atelectasis in the left upper lobe with bronchial wall thickening, stenosis, dilatation, and mucoid impaction. We performed bronchoscopy and found a well-circumscribed mass on the left upper lobe bronchus. The mass was removed by flexible bronchoscopy using an electrosurgical snare and diagnosed with lipoma. An endobronchial lipoma is a rare benign tumor that can be treated by a surgical or endoscopic approach. We report the successful removal of endobronchial lipoma via flexible bronchoscopic electrosurgical snare.

Topic: Tracheal and airway disorders
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Sequence‐specific chemical modification of a 365‐nucleotide‐long DNA fragment with an alkylating oligonucleotide derivative

An aromatic 2‐chloroethylamino group was attached to the 5'‐terminal phosphate of the oligodeoxyribonucleotide pCCCTCTTTCTT. The oligonucleotide derivative prepared was used for modification of the 365‐nucleotide‐long DNA fragment. It was found that modification of the fragment proceeds in a sequence‐specific way at 3 guanosine residues within the sequence complementary to the oligonucleotide reagent.

Topic: DNA and Nucleic Acid Chemistry
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
How Aberrant N-Glycosylation Can Alter Protein Functionality and Ligand Binding: an Atomistic View

These files contain the input files, topologies and restart files to run the simulations described in accepted paper: <strong>How Aberrant <em>N</em>-Glycosylation Can Alter Protein Functionality and Ligand Binding: an Atomistic View </strong> Matteo Castelli<sup>1</sup>, Pengrong Yan<sup>2</sup>, Anna Rodina<sup>2</sup>, Chander S. Digwal<sup>2</sup>, Palak Panchal<sup>2</sup>, Gabriela Chiosis<sup>2,3,</sup>*, Elisabetta Moroni<sup>4,</sup>*, Giorgio Colombo<sup>1,2,5</sup> Department of Chemistry, University of Pavia, Pavia, Italy. Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. SCITEC-CNR, Milano, Italy.

Topic: Glycosylation and Glycoproteins Research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Chromohalobacter salexigens sp. nov., a moderately halophilic species that includes Halomonas elongata DSM 3043 and ATCC 33174.

Two strains that were originally isolated and characterized as members of the moderately halophilic species Halomonas elongata, strains DSM 3043 (= 1H11) and ATCC 33174 (= 1H15), were studied in detail. Their complete 16S rRNA sequences were determined and, when compared to sequences available from the databases, they showed a close phylogenetic relationship to Chromohalobacter marismortui. In addition, DNA-DNA hybridization experiments showed that both strains are members of the same species, but their DNA relatedness to the type strains of Halomonas elongata, ATCC 33173T, and Chromohalobacter marismortui, ATCC 17056T, is very low. Phenotypically, the two strains showed very similar features, related to those of Chromohalobacter, but clear differences were found between these two strains and Chromohalobacter marismortui. On the basis of these data, it is proposed that Halomonas elongata DSM 3043 and ATCC 33174 should be included in a new species of the genus Chromohalobacter, Chromohalobacter salexigens sp. nov. The type strain is DSM 3043T (= ATCC BAA-138T = CECT 5384T = CCM4921T = CIP106854T = NCIMB 13768T).

Topic: Genomics and Phylogenetic Studies
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Density, Viscosity, and Conductivity for the Binary Systems of Water + Dual Amino-Functionalized Ionic Liquids

The density, viscosity, and conductivity were investigated for binary mixtures of water and three ionic liquids (ILs), respectively: (3-aminopropyl) tributylphosphonium L-alpha-aminopropionic acid salt ([aP(4443)][Ala]), (3-aminopropyl) tributylphosphonium L-alpha-aminoisovaleric acid salt ([aP(4443)][Val]), and (3-aminopropyl) tributylphosphonium L-alpha-amino-4-methylvaleric acid salt ([aP(4443)][Leu]). The mole fractions of water increased from 0.00 to 0.75, and the temperature varied from (298.15 to 343.15) K. It was found that the viscosity decreased while conductivity increased with the increase of temperature and water content. As the alkyl side-chains of the amino acid anions which might play a role of steric hindrance were lengthened, the density (rho), viscosity (eta), and conductivity (sigma) follow the order of rho([aP4443][Ala]) &gt; rho([aP4443][Val]) &gt; rho([aP4443][Leu]), eta([aP4443][Ala]) &lt; eta([aP4443][Val]) &lt; eta([aP4443][Leu]), and sigma([aP4443][Ala]) &gt; sigma([aP4443][Val]) &gt; sigma([aP4443][Leu]), respectively. The temperature-dependent density is fit for the quadratic equation. The temperature dependence of viscosity and conductivity can be described by the Vogel-Tammann-Fulcher (VTF) equation.

Topic: Ionic liquids properties and applications
Subfield: Catalysis
Field: Chemical Engineering
Domain: Physical Sciences
Analisis Persepsi Pelaku Usaha Mikro dan Kecil (UMK) atas Kebijakan Sertifikasi Halal

Halal certification on a product in circulation is an action that must be taken as a form of halal assurance for consumers and producers. As stated in the Regulation of the Minister of Religion of the Republic of Indonesia Number 20 of 2021 concerning Halal Certification for Micro and Small Business Actors Part One Article 2. Therefore, the Government of Indonesia implements regulations that require all business actors to obtain halal certification. The focus of this research is: 1) What is the perception of micro and small businesses on halal certification policy? 2) What are the factors that influence the perception of micro and small enterprises on halal certification policy?. To answer the research focus above, using a skinative approach method with a type of case study research. The research subjects were selected by snowball sampling and used data collection techniques in the form of observation, interviews, and documentation. The data analysts used in the study using Miles &amp; Hurberman and the validity of the data include, credibility, transferability, and confermability. The results in the study show that: 1) There are 70% or 7 business actors know that halal certification can provide good, to meet the rights of consumer needs, can provide an increase to micro and small enterprises. And this perception influences business actors to have the desire to have halal certification. There are 40% or 4 business actors who want their products to have halal certification. 2) There is still a lack of information, knowledge, and assistance about the existence of the policy. and burdensome due to lack of understanding regarding the procedure for making halal certification for micro and small enterprises in Sumbersari sub-district, Jember Regency from the authorities.

Topic: Islamic Finance and Banking Studies
Subfield: Accounting
Field: Business, Management and Accounting
Domain: Social Sciences
Shy–bold behaviours in dragonfly larvae: syndromes or personality?

Abstract Researchers have recently focused efforts on the study of animal personality and behavioural syndromes, exploring consistent behaviour variations and correlations. Dragonflies, with their diverse behaviours, have become good models to improve our knowledge on animal behaviour. Here, we addressed whether dragonfly larvae exhibit shy–bold behaviours, akin to personality traits or behavioural syndromes. We made a series of experiments where we restrained larvae and noted their behaviour — some larvae exhibited thanatosis, playing dead when touched, while others boldly reacted with aggression. Later, we tested how active the larvae were in a water channel by analysing their movement. These experiments were made in three trials with 15 days apart. Our results show that larvae display consistent behaviours over time, hence, they exhibit personalities in terms of predator avoidance behaviour. Nevertheless, we found little evidence for behavioural syndromes. The boldness of larvae was only partially correlated with larval activity in the experimental channel. In conclusion, dragonflies emerge as a potential model for insect personality, prompting future studies on how cognition and personality impact fitness in different environments. Unravelling whether behavioural syndromes are a true phenomenon in these insects awaits further investigation.

Topic: Plant and animal studies
Subfield: Ecology, Evolution, Behavior and Systematics
Field: Agricultural and Biological Sciences
Domain: Life Sciences
GDPR v. GDPL

Purpose ”“ The main purpose of this article is to analyze the aspects of the responsiveness approach adopted by European and Brazilian lawmakers in the elaboration of data protection rules, such as GDPR and LGPD. &#x0D; Methodology ”“ The applied methodology is based on the responsive regulation theory and, additionally, the network governance theory, through the comparative analysis of personal data protection legal frameworks in Brazil and the EU.&#x0D; Findings ”“ Based on the comparative analysis of the GDPR and the LGPD, it is verified the adoption of escalated regulatory techniques of Ayres and Braithwaite’s enforcement pyramid in the developed of these norms, as a strategy adopted by lawmakers to guarantee a greater compliance from regulated entities.

Topic: Regulation and Compliance Studies
Subfield: Strategy and Management
Field: Business, Management and Accounting
Domain: Social Sciences
The Tumor Microenvironment in Thyroid Cancer: A Scoping Review of Components, Analytical Methods, and Clinical Associations

Background: Thyroid cancer is the most frequent endocrine malignancy, encompassing subtypes such as papillary, follicular, medullary, and anaplastic carcinomas. Despite the generally favorable prognosis, heterogeneity in tumor biology underscores the relevance of the tumor microenvironment (TME), which comprises immune and stromal cells, extracellular matrix, cytokines, and molecular signaling networks that influence tumor progression and therapeutic response. Several analytical methods—including immunohistochemistry, flow cytometry, single-cell RNA sequencing, and spatial transcriptomics—are employed to characterize the TME. However, evidence on TME components, methodologies, and clinical associations in thyroid cancer remains fragmented and has not been comprehensively mapped. Objective: This scoping review aims to identify, catalogue, and describe studies of the TME in thyroid cancer, focusing on investigated components, analytical techniques, and reported associations with clinical outcomes. Methods: The review will follow the Joanna Briggs Institute (JBI) methodology for scoping reviews and be reported according to PRISMA-ScR. Literature searches will be conducted in MEDLINE (PubMed), Embase, LILACS, Web of Science, and Scopus, complemented by grey literature, citation tracking, and manual reference screening. Eligible sources will include original studies with human thyroid cancer samples (tissue, blood, aspirates) that assess TME features using histological, molecular, or spatial analytical methods. Two reviewers will independently perform study selection and data extraction, with results synthesized descriptively. Evidence maps and visualizations will summarize the distribution of TME components, methodological platforms, and clinical associations. Results: Findings will be presented through narrative synthesis, structured tables, and visualizations, highlighting which TME components have been most studied across thyroid cancer subtypes, the diversity of analytical methods employed, and the consistency of reported clinical correlations. Conclusion: This review will provide the first comprehensive map of TME research in thyroid cancer, identifying evidence clusters, methodological trends, and knowledge gaps. These insights will inform future translational studies and contribute to the refinement of therapeutic strategies targeting the TME.

Topic: Lipoproteins and Cardiovascular Health
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Development, multiplexing, and application of ARMS tests for common mutations in the CFTR gene.

The amplification refractory mutation system (ARMS) is a simple, rapid and reliable method for the detection of any mutation involving single base changes or small deletions. We have applied ARMS methodology to the detection of mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Single ARMS tests have been developed for 11 CFTR mutations found in the northwest of England. ARMS reactions for the most common mutations have been multiplexed to give a test which will detect the presence of the delta F508, G551D, G542X, and 621 + 1G----T mutations in a DNA sample. The multiplex test has been validated by the analysis of over 500 previously genotyped samples and has been found to be completely accurate. The rapid detection of the most common mutations has enabled early molecular confirmation of suspected cystic fibrosis in neonates, rapid typing of cystic fibrosis patients and their relatives, and testing of sperm and egg donors.

Topic: Cystic Fibrosis Research Advances
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Nutrient Composition, Physical and Sensory Characteristics of Bread Nutrified with Abattoir Waste

Objective: The study was designed to determine nutrient composition, evaluate physical and organoleptic properties of bread incorporated with abattoir waste (blood meal) as protein and micronutrient fortifier. Methods: Fresh abattoir blood meal was collected from Anyigba abattoir, divided into two equal parts, one part kept frozen until used and the other prepared into powder (6.5% moisture content, 180 micron particle size) and packaged into heat sealed HDPE bag for use. Both liquid and powdered abattoir wastes were each incorporated into bread recipe at four (4) different levels: 5.0%, 7.5%, 10.0% and 12.5% of flour, and then baked into bread loaves, making eight experimental samples plus the control, using standard methods and procedures. The physical characteristics and chemical composition of the bread loaves were determined. Their sensory qualities as well as acceptability were also evaluated. The data obtained were subjected to statistical analysis.Results: Protein contents of experimental bread loaves increased with increase in abattoir waste levels from 8.98% - 13.31%, showing appreciable increase above 6.89% obtainable in conventional bread. Similarly, the range of values for micronutrients content of the experimental bread were: Fe (14.5-23.1 mg /100g), P (24.8-37.8mg/100g) and I2 (0.100-0.261 mg/100g).They also showed significant increases over and above the respective micronutrient contents of traditional bread. There were little or no variations in physical characteristics, except the weight of bread loaves. The crust and crumb colours of bread loaves containing liquid abattoir waste (at 5.0 – 12.5% levels) and powder (at 5.0% level) were more cherished, though significantly different (P&lt;0.05) from the conventional loaf of bread. The taste and detectable flavour of all experimental bread samples were similar, with characteristic meat flavour, significantly different (P&lt;0.05) from the control. Samples containing both liquid and dried abattoir waste at 5% and 7.5% levels had firm and brittle crumb similar to the conventional bread. Conclusion: It is possible to use liquid/dried abattoir blood meal to improve the protein and micronutrient (Fe, P, I2) contents of bread, also give acceptable novel bread product.

Topic: Food Industry and Aquatic Biology
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Some recent progress of biharmonic submanifolds

In this note, we give a brief survey on some recent developments of biharmonic submanifolds. After reviewing some recent progress on Chen's biharmonic conjecture, the Generalized Chen's conjecture on biharmonic submanifolds of non-positively curved manifolds, and some classifications of biharmonic submanifolds of spheres, we give a short list of some open problems in this topic.

Topic: Geometric Analysis and Curvature Flows
Subfield: Applied Mathematics
Field: Mathematics
Domain: Physical Sciences
Chaos Expansions, Multiple Wiener-Ito Integrals, and Their Applications

Multiple Wiener-Ito Integrals: An Introductory Review, C. Houdre, V. Perez-Abreu, and A.S. Ustunel. The Hu-Meyer Formula: A View of the Problem with Special Attention to the Poisson Case, J.L. Sole and F. Utzet. Remarks on the Existence of k-Traces, G.W. Johnson and G. Kallianpur. Multiple Wiener-Ito Integrals and a Multivariate Version of Schoenberg's Theorem, O. Kallenberg. The State of Decoupling: A Survey, J. Szulga. MWI Expansions for Functionals Related to Level-Crossing Counts, E.V. Slud. Scaling Limits of Solutions of Burgers' Equation with Singular Gaussian Initial Data, D. Surgailis and W.A. Woyczynski. Weak Convergence in Dynamical Systems to Self-Similar Processes with Time Average Representation, M.T. Lacey. On Exact Tails for Limiting Distributions of U-Statistics in the Second Gaussian Chaos, P. Imkeller. Limit Theorems for Empirical Processes under Dependence, M.A. Arcones and B. Yu. Mixing for Multiple Wiener-Ito Integral Processes, D.W. Chambers. Zero-One Laws for Multiple Stochastic Integrals, J. Rosinski and G. Samorodnitsky. Continuity of Some Gaussian Chaoses, M.B. Marcus. Some Formulas for Anticipative Girsanov Transformations, J.A. Leon and P. Protter. Absolute Continuity of Processes and a Derivation Rule, M.E. Caballero and B. Fernandez. Smoothness of Local Time and Related Wiener Functionals, D. Nualart and J. Vives. Distributions on Wiener Space and Fluctuation Limits of Poisson Systems of Brownian Bridges, L.G. Gorostiza. Ito-Ramer, Skorohod and Ogawa Integrals with Respect to Gaussian Processes and Their Interrelationship, L. Gawarecki and V. Mandrekar.

Topic: Stochastic processes and financial applications
Subfield: Finance
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Symbiotic &amp;#x201C;main manufacturer-supplier&amp;#x201D; relationship model for civil aircraft manufacturing

The supplier of civil aircraft manufacturing industry is an important part in the supply chain system for civil aircraft. Hence, strengthening supplier relationship management for civil aircraft manufacturers is significant to reduce costs and improve their core competitiveness. In this paper, civil aircraft manufacturer-supplier symbiotic relationship analysis with the logistic model is constructed to make correlative analysis, which shows that different measures can be taken for different types of supplier relations.

Topic: Quality and Supply Management
Subfield: Management Information Systems
Field: Business, Management and Accounting
Domain: Social Sciences
A Study on Favorability and Satisfaction after Using Natural Toothpaste among College Students

Objectives: Toothpaste, which is essential for toothbrushing, suppresses the formation of calculus to clean the oral cavity, prevent tooth decay and periodontitis, avoid dental plaque, and remove halitosis. However, numerous recent reports on the side effects and toxicity of the chemical compounds in toothpaste have led to active research aiming to develop oral hygiene products that contain safe substances, thereby increasing the development of and interest in natural materials. According to many studies, natural toothpaste has been made from Artemisia capillaris Thunberg, which has strong antibacterial effects throughout the human body; cinnamon, which is used as food and medicine, has a strong scent that helps control halitosis and suppress fungal growth. This study aims to evaluate the favorability of and satisfaction with the use of toothpaste that contains natural materials extracted from A. capillaris Thunberg and cinnamon. Methods: In the experiment, college students used natural toothpaste for five days, and their oral hygiene before and after use was assessed. For statistical analysis, a frequency analysis and a confidence interval test were run using the software SPSS WIN 25.0. Results: Most of the subjects used the rotation method, and 72.5% of them had no experience using natural toothpaste. The expected effect of the natural toothpaste was higher in halitosis reduction than in bacterial reduction. The use of the natural toothpaste also showed a reduction in oral resident bacteria. Conclusions: The favorability of and satisfaction with the use of natural toothpastes were determined. The natural toothpaste effectively removed oral resident bacteria.

Topic: Food Quality and Safety Studies
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences