jimnoneill/paper-to-field-training huggingface dataset:
Assess the Various Risks Associated in Build Operate Transfer (BOT) Infrastructure Projects: Case study of (Shirwal-Lonand-Phaltan-Baramati Road Project)

In INDIA, BOT (Build Operate Transfer) approach has given an undeniably well known task financing to push toward framework improvement. There are numerous complexities in ventures on account of the assortment of elements in undertaking's pattern and furthermore the reliance of task. Because of the complexities and their drawn out working, the tasks meet with vulnerability and various dangers. This exploration study is to concentrate on the Indian foundation segment with an accentuation on various undertakings hazard factor . The advancement of the development area in india has been compratelly moderate . BOT(Build Operate Transfer) implies the administration move the admission to Private Company and the organization is liable for building, working the undertaking, and afterward move the task back to the legislature when the concession time frame terminates. The principle reason for this paper is to explore monetary hazard, specialized hazard, unique and support chance, remote trade risk and commercial chance in BOT projects. BOT venture is exposed to numerous dangers lastly it is changed over into money related risk.base on the audit the basic hazard are found :-change in law, cost overrun, delay in delay in endorsement , development plan budgetary shutting , traffic modification , natural hazard , and so forth The reason for this paper is to examine the hazard related with BOT plans in India

Topic: Construction Project Management and Performance
Subfield: Management Science and Operations Research
Field: Decision Sciences
Domain: Social Sciences
Diagnostic methods for pancreatic cancer and their clinical applications (Review)

Pancreatic cancer (PC) is often considered one of the most aggressive and deadly types of cancer, distinguished by its swift advancement and unfavorable prognosis. This reality highlights the vital necessity for early detection to improve patient survival rates. In recent years, notable advancements in medical technology have catalyzed the development of various diagnostic approaches, including imaging modalities, tumor markers, tissue biopsy, liquid biopsy, volatile organic compounds and nanomaterials. However, despite the promising progress in these diagnostic tools, numerous challenges persist, particularly concerning the sensitivity and specificity of these methods, as well as the complexities involved in their practical implementation in everyday clinical practice. The present review article aims to produce a thorough analysis of the applicability of each diagnostic method available for PC, highlighting their respective strengths and limitations while providing clinical recommendations aimed at enhancing the early identification of this formidable disease.

Topic: Extracellular vesicles in disease
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Supplemental Figures 1-5 from Akt-Dependent Glucose Metabolism Promotes Mcl-1 Synthesis to Maintain Cell Survival and Resistance to Bcl-2 Inhibition

Supplemental Figures 1-5 from Akt-Dependent Glucose Metabolism Promotes Mcl-1 Synthesis to Maintain Cell Survival and Resistance to Bcl-2 Inhibition

Topic: Cell death mechanisms and regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
LHD tsmesh_h #145074.1 (analyzed)

Effective minor radius (reff) and local magnetic field (B_r: radial magnetic field, B_z: axia magnetic field, B_phi: circumferential or azimuthal magnetic field) at horizontally elongated cross section.

Topic: Down syndrome and intellectual disability research
Subfield: Public Health, Environmental and Occupational Health
Field: Medicine
Domain: Health Sciences
[Relapse of pulmonary tuberculosis in the context of tuberculosis-HIV co-infection in Abidjan (Côte d'Ivoire). Short note].

A cohort study was carried out from October 2001 to March 2002, in order to analyze the main characteristics of 53 adults patients (38 HIV-positive and 15 HIV-negative), who had a relapse of pulmonary tuberculosis. The observance in the first period of the treatment of tuberculosis was regular in 79% of tuberculous patients infected by the HIV (30/38) and in 87% of tuberculous patients who where HIV-negative (13/15) (p = 0.7). The relapse occurred before one year after recovery in 74% among the HIV-positive (28/38) and in 33% among the HIV-negative patients (5/15) (p = 0.00). Most of the HIV-positive patients (74%) had CD4 counts under 200/mm3 and 80% of the HIV-negative patients had more than 500 CD4 counts/mm3 (p = 0.00). After two months of retreatment following the relapse diagnosis, the rate of improvement in patients was about 16% in HIV infected (6/38) and about 67% in HIV-negative patients (10/15) (p = 0.00).

Topic: Tuberculosis Research and Epidemiology
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
magistyka społeczno-kulturowa w średniowiecznej Serbii, czyli o strategii budowania wizerunku serbskich panujących

In the article, a phenomenon of promotion and marketing in the medieval Serbia was discussed, as well as the strategies of creating a specific, desired and functional image of the ruling dynasties. Due to this, the basic communication practices were recalled that is, a management of impression, building the so-called brand (social, political, cultural property of the dynasty, its family pattern), and also specifically conceived branding itself (that is, a management of consciousness and value of the dynastic brand), what ultimately proved that the lineage of social-cultural usage of images, along with the models and devices serving the politics of public relations is deeply rooted in the middle ages. The phenomenon of promotion and marketing in the medieval Serbia was presented on the basis of the medieval Serbian literature, hagiography, hymnography, historiography, and iconographic implementations were also included. The article presents images of rulers and dynasties prevailing in the historical, religious and ideological context, the phenomenon of promotion and marketing in the context of characteristic ideological structures, such as state and church tradition, imperial-monastic tradition, charismatic dynasty, sanctity of the ruling family, land and the Serbian nation e.t.c. The timeless phenomenon of promotion and marketing has been presented as a lasting component of shaping the culture model of the medieval Serbia.

Topic: Byzantine Studies and History
Subfield: Classics
Field: Arts and Humanities
Domain: Social Sciences
Mathematical Modeling of a Hydraulic Lifting System for the Autodock Docking Leveler

This paper focuses on aspects regarding the design of a universal lifting system (actuation) of the platform of a product such as hydraulically operated docking levelers, with example on the Autodock leveler, which can be found as a component of the external docking stations of logistics warehouses.Aspects regarding the configuration of this product are treated as well as functional aspects reflected through a mathematical model that describes the interdependence between the parameters that describe the movement of this mechanical system.It also describes the situation of the stresses that occur in this system during operation and how they vary depending on certain key parameters.Summarizing, an image is created on a design method that imposes a set of conditions and universal steps valid for the design of the leveler lifting system for any special configuration found in the required configuration limits.The aim of the paper is to form a clear picture of the interdependence of the parameters that shape the designed lifting system.

Topic: Industrial Engineering and Technologies
Subfield: Mechanical Engineering
Field: Engineering
Domain: Physical Sciences
SH2729646.08FU

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.

Topic: Gaze Tracking and Assistive Technology
Subfield: Human-Computer Interaction
Field: Computer Science
Domain: Physical Sciences
Intermediate and Long-term Outcomes Following Surgical Decompression of Neurogenic Thoracic Outlet Syndrome in an Adolescent Patient Population

Background: Although the diagnosis of thoracic outlet syndrome (TOS) is often missed, outcomes from surgical intervention significantly improve patient satisfaction. This article seeks to highlight patient characteristics, intraoperative findings, and both short and long-term outcomes of thoracic outlet decompression in the adolescent population. Methods: A retrospective chart review of patients between the ages of 13 and 21 years with a clinical diagnosis of neurogenic thoracic outlet syndrome (NTOS) who were treated surgically between 2000 and 2015 was performed. Data points including preoperative patient characteristics and intraoperative findings were collected. In addition, patient-reported outcome scores, including Visual Analog Scale (VAS), Single Assessment Numeric Evaluation (SANE), Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) questionnaire, Cervical Brachial Symptom Questionnaire (CBSQ), and NTOS index, were obtained for a cohort of patients with follow-up ranging from 2 to 15 years. Results: The study population consisted of 54 patients involving 61 extremities. The most common procedures included neurolysis of the supraclavicular brachial plexus (60, 98.4%), anterior scalenectomy (59, 96.7%), and middle scalenectomy (54, 88.5%). First rib resection (FRR) was performed in 28 patients (45.9%). Long-term outcomes were collected for 24 (44%) of 54 patients with an average follow-up of 69.5 months (range, 24-180 months). The average VAS improved from 7.5 preoperatively to 1.8 postoperatively. The average SANE increased from 28.9 preoperatively to 85.4 postoperatively. The average postoperative scores were 11.4 for the QuickDASH, 27.4 for the CBSQ, and 17.2 for the NTOS index. Subgroup analysis of patients having FRR (28, 45.9%) demonstrated no difference in clinical outcome measures compared with patients who did not have FRR. Conclusion: Surgical treatment of NTOS in adolescent patients has favorable intermediate and long-term outcomes.

Topic: Peripheral Nerve Disorders
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Robotic-Assisted Gait Training Therapies for Pediatric Cerebral Palsy: A Review

Background : Children and adolescents with CP experience many types of disability and functional impairment that effect the gait cycle. New robotic gait therapies adapted to pediatric patients provide a safe, highly repetitive, and task-specific therapeutic venue for the rehabilitation and elicitation of a more natural walking gait. While the use of robotic-assisted gait training (RAGT) is a relatively novel therapeutic approach to gait therapy, several studies have examined the efficacy of this therapeutic modality in pediatric patients with CP. Purpose : The purpose of this review is to examine the trends in the therapeutic efficacy of utilizing RAGT therapy as a gait restorative modality for children with CP. Results : The present studies show that RAGT therapy may provide multiple therapeutic benefits to children with CP, including statistically significant improvements in gross motor function and multiple gait characteristics. Also, RAGT therapy may be a safe and favorable complement to current physiotherapy regimens. Conclusion : As various degrees of functional improvement are a noticeable trend among all presented studies, further study in this therapeutic technique is warranted, and implementation of similar therapeutic protocol may be valuable to a rehabilitation care plan. The highly repetitive and task-specific nature of RAGT may provide a valuable paradigm for children with CP whom have never learned a normal gait pattern.

Topic: Cerebral Palsy and Movement Disorders
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
A Supervised Correlation Coefficient Method: Detection of Different Correlation

Correlation coefficient is a kind of feature selection method that can effectively choose the most appropriate feature and reducing data dimensions. There are several supervised correlation coefficient methods have been considered. However, few methods can detect both the linear correlation and non-linear correlation. Our study considered a supervised correlation coefficient method, named consistency detection, to detect linear and non-linear correlation. Our results show consistency detection can better retain the dimensions of classification and detect correlation than Pearson correlation coefficient in some way.

Topic: Data Management and Algorithms
Subfield: Signal Processing
Field: Computer Science
Domain: Physical Sciences
The major phosphorylation site of the NADPH oxidase component p67phox is Thr233

Phosphorylation of p67phox was shown to increase two- to three-fold upon stimulation by PMA, N-formylmethionyl-leucylphenylalanine or serum-opsonized zymosan. Phosphopeptide mapping showed one major tryptic peptide for p67phox immunoprecipitated from resting or stimulated cells. In vitro phosphorylation of p67phox by isolated cytosol or mitogen-activated protein kinase also generated the same phosphopeptide. Results of cyanogen bromide digestion and HPLC–MS suggested that Thr233 was the phosphorylated residue. Mutagenesis of Thr233 to alanine resulted in loss of phosphorylation in vitro. In the present work, Thr233 has been identified as the major phosphorylation site of p67phox, which is situated in a proline-rich domain.

Topic: Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Biomechanical evaluation of 10 configurations of a small external fixator set.

The small AO (Synthes, Paoli, Pa) external fixator is a valuable tool for the treatment of distal radius fractures. The construct has many possible bar and pin configurations. However, there are no data regarding which construct is optimal with respect to strength and versatility. We tested 10 configurations to determine bending stiffness, rotation, and axial loading. Although slight variations were found between constructs for bending and rotation forces, there were marked differences between constructs during axial loading. A frame design without bar-to-bar clamps was determined stiffest. However, this configuration may be more difficult to apply and adjust in the clinical setting. Although an "ideal" construct applicable to all fracture types does not exist, knowledge of the strengths of various configurations may allow for optimization of fixator assembly to meet specific clinical needs.

Topic: Orthopedic Surgery and Rehabilitation
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
The multiple faces of front line managers

Purpose – The purpose of this paper is to present exploratory research on the potential variation of front line manager (FLM) types and attendant causal links between FLM style and employee outcomes. It challenges the value of a homogenous FLM construct and tests for variation in FLM styles which may affect behaviours and employee outcomes. Design/methodology/approach – A set of discreet FLM types is defined from extant theory and literature (named here as Policy Enactor; Organizational Leader; and Employee Coach). Each type and its relationship to employee outcomes is explored empirically using survey data and qualitative interviews with a small sample of employees ( n =46 employees across eight FLM groups) within a multi-national manufacturing plant. Findings – The findings provide preliminary support for an FLM “type” construct. Employees reported a significant dominance of the “Organizational Leader” type for one FLM, while across a broader set of FLM’s the proportions showed measurable variation. The qualitative data provides context examples that help explain FLM typologies and link to employee outcomes. Originality/value – Much of current literature explores the FLM construct as a singular construct, relying on its contextual relevance for definition within a certain discipline. This paper focuses on combining these contextual experiences to present a multi-faceted construct for the role of FLMs within the employment relations literatures. By moving from the implicit to the explicit, the paper offers a conceptual lens for quantitative and qualitative exploration of the role of FLM types. As a result, attendant and subsequent FLM and employee behaviours may be better examined and possibly better specified. To add value to this contribution longitudinal and more extensive data sets could be examined and tested in the future.

Topic: Job Satisfaction and Organizational Behavior
Subfield: Organizational Behavior and Human Resource Management
Field: Business, Management and Accounting
Domain: Social Sciences
European League Against Rheumatism Sjögren's Syndrome Disease Activity Index and European League Against Rheumatism Sjögren's Syndrome Patient‐Reported Index: A Complete Picture of Primary Sjögren's Syndrome Patients

Objective The European League Against Rheumatism (EULAR) Sjögren's Syndrome (SS) Disease Activity Index (ESSDAI) and the EULAR SS Patient‐Reported Index (ESSPRI) were recently developed. We aimed to determine whether patients' symptoms differed between patients with and without systemic involvement and if the disease‐specific indices correlated with each other in primary SS. Methods Fifteen French centers included 395 primary SS patients in the Assessment of Systemic Signs and Evolution in Sjögren's Syndrome Cohort. At enrollment, physicians completed the ESSDAI, the SS Disease Activity Index (SSDAI), and the Sjögren's Systemic Clinical Activity Index (SCAI), and patients completed the ESSPRI, the Sicca Symptoms Inventory, and the Profile of Fatigue and Discomfort. All scores were compared between patients with and without systemic involvement. Correlations between scores of systemic activity and patients' symptoms were obtained. Results At enrollment, 120 (30.4%) patients had never experienced systemic complication and 155 (39.2%) patients and 120 (30.4%) patients had, respectively, only past or current systemic manifestations. Past or current systemic patients had higher levels of symptoms, except dryness. The ESSDAI did not correlate with the patient‐scored ESSPRI (rho = 0.06, P = 0.30), whereas the SSDAI and the SCAI, which include subjective items, did correlate (rho = 0.28 and 0.25, respectively; P &lt; 0.0001 for both). Conclusion Alterations of common patient‐reported outcomes are present in all patients with primary SS, including those with systemic complications. However, patient symptoms and systemic complications are 2 different facets of primary SS. Therefore, the use of both systemic and patients' indices, such as the ESSDAI and ESSPRI, are useful. Since these 2 facets weakly overlap, one should identify which of both components is the main target of the treatment to test, when designing clinical trials in primary SS.

Topic: Salivary Gland Disorders and Functions
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Supplemental materials and methods, supplemental references and supplemental figure legends from Loss of RASSF4 Expression in Multiple Myeloma Promotes RAS-Driven Malignant Progression

&lt;p&gt;Information about material and methods, that further support the date described in this article. Additional references and legends to the supplmental figures are also provided.&lt;/p&gt;

Topic: Ubiquitin and proteasome pathways
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
THE NATURE OF THE VEGETATIONAL CHANGES AT ABOUT 5000 <scp>b.p.</scp> WITH PARTICULAR REFERENCE TO THE ELM DECLINE: FRESH EVIDENCE FROM CONNEMARA, WESTERN IRELAND

S ummary Results of palaeoecological investigations on a core from Lough Sheeauns, N.W. Connemara, a small lake sited in an area with a dense concentration of megaliths datable to the Neolithic, are reported. Pollen analysis, involving continuous sampling over a 41 cm interval spanning the elm decline (c. 5000 B.P.), permitted a detailed reconstruction of the vegetational changes and the nature of human impact. The pollen data are supplemented by chemical analysis and a chronology is provided by radiocarbon dating. Farming, including cereal cultivation, in the century prior to the elm decline is demonstrated. The elm decline emerges as a distinct feature in both percentage and concentration pollen diagrams. It is argued that neither an anthropogenic nor a climatic explanation for that event is sustainable in the light of the available evidence; a disease hypothesis is favoured. In the immediate post‐elm decline period, Landnam, involving major woodland clearance in the context of a pastoral‐based Neolithic economy, is recorded as a distinctive feature in the pollen record.

Topic: Archaeology and ancient environmental studies
Subfield: Paleontology
Field: Earth and Planetary Sciences
Domain: Physical Sciences
Comparative study of new autologous material, bone‐cartilage composite graft, for ossiculoplasty with Polycel<sup>®</sup> and Titanium

Objective Ossiculoplasty is a surgical procedure that recreates sound transmission of the middle ear in conductive hearing loss. Various materials have been used for ossicular reconstruction, but the most ideal material for ossiculoplasty remains controversial. The purpose of this study was to introduce a novel method of autologous ossiculoplasty, bone‐cartilage composite graft ( BCCG ) and to compare its surgical results with different types of ossiculoplastic prostheses. Study Design A retrospective study was performed in a tertiary referral centre. Methods Data of 275 patients who received ossiculoplasty using the three different materials of BCCG , Polycel ® and titanium were analysed according to type of ossiculoplasty: partial or total ossicular replacement prosthesis ( PORP or TORP ). Hearing results, complication rates and clinical parameters including age, sex, past history, preoperative diagnosis and surgery type were compared among different groups. Results Ossiculoplasty with BCCG showed satisfactory hearing outcomes and the lowest complication rate among the three different materials. In particular, its extrusion rate was 0%. Conclusion We propose that the BCCG technique is a useful alternative method for ossiculoplasty, with proper patient selection.

Topic: Ear Surgery and Otitis Media
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences