jimnoneill/paper-to-field-training huggingface dataset:
Quantitative Trait Loci (QTL) that Underlie SCN Resistance in Soybean [ Glycine max (L.) Merr.] PI438489B by ‘Hamilton’ Re - combinant Inbred Line (RIL) Population

Soybean cyst nematode caused by Heterodera glycines Ichinohe is the most devastating pest in soybean [Glycine max (L.) Merr.]. Resistance to SCN is complex, polygenic, race and cultivar specific, and it is controlled by several quantitative trait loci (QTL). Our objective was to identify and map QTL for SCN resistance to races 3 (HG Type 0) and 5 (HG Type 2.5.7) using a high density SNP-based genetic linkage map based on the PI438489B by 'Hamilton' (PIxH, n=50) recombinant inbred line population. The PI438489B by Hamilton map contained 648 SNPs distributed on 31 LGs with coverage of 1,524.7 cM and an average distance of 2.35 cM between two markers (Kassem et al., 2011). Using interval mapping (IM) and composite interval mapping (CIM), eight QTL were identified for SCN resistance to races 3 and 5 on 7 different soybean chromosomes. Four QTL for resistance to SCN race 3 were identified and mapped on chromosomes 7, 13, 15, and 16. Similarly, four QTL for resistance to SCN race 5 were identified and mapped on chromosomes 5, 8, and 11. The QTL identified here will be highly beneficial in breeding programs to develop cultivars with resistance to both SCN races 3 and 5.

Topic: Soybean genetics and cultivation
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
What? Why? When? How? Where? of Technology-Based Bibliometric Review

The proliferation of bibliometric review articles is a true reflection of how bibliometrics is gaining popularity and has been widely adopted in various disciplines. The growing interest of scholars has encouraged us to dwell upon the what, why, when, how, and where of bibliometric literature reviews. The study explained the bibliometric review with the standpoint that it can be considered a strong review method for analyzing a large volume of data and scholars can supplement their traditional reviews with bibliometric reviews to strengthen their knowledge. This will help researchers to justify the (a) need for a study on the particular topic; (b) type or method of review chosen; (c) number of articles selected; (d) inclusion and exclusion criterion; (e) method of analysis; and (f) presentation of the findings.

Topic: scientometrics and bibliometrics research
Subfield: Statistics, Probability and Uncertainty
Field: Decision Sciences
Domain: Social Sciences
Epidemiological Investigation of A Goat Rabies Outbreak and Assessment of Knowledge, Attitudes, and Practices of Communities Regarding Rabies in the Rural Commune of Sabou, Burkina Faso

Background: Dog-mediated human rabies is one of the top five priority zoonotic diseases identified for the One Health multisectoral engagement in Burkina Faso. Integrated approaches are required in endemic areas for reliable data collection and improved management of bite victims. This study aimed to assess the knowledge, attitudes, and practices of communities regarding rabies and preventive methods.Subjects and Method: A cross-sectional household survey was conducted in the Commune of Sabou after a goat rabies confirmation. A structured questionnaire was administered to 305 house-hold members to capture data. The dependent variables in this study were the knowledge of rabies and animal vectors, the action to be taken regarding the biting animal, the main challenges to PEP coverage, the knowledge of preventive measures, and the minimum age recommended for primo-vaccination. The independent variables in this study were gender, level of education, professional status, and dog-owning status. The study was analyzed using the Chi-Square test.Results: The results provided that the suspected goat was infected by the rabies virus. Subsequently, the outbreak joint investigation initiated involved key local stakeholders. Data collected during the investigation raised the need for counter-measures such as identification of awareness gaps, organization of a dog rabies vaccination, and awareness-raising campaigns in the local communities. The household survey revealed low awareness about animals involved in human rabies transmission, the common routes of transmission, and the postexposure prophylaxis. Moreover, hindrances to postexposure prophylaxis access cited by the participants were related to frequent vaccine shortage (39.7%) as well as financial inaccessibility (60.3%). In addition, 40% of participants were not well aware of pet rabies prevention and reported only 67.6% of owned dogs were vaccinated.Conclusion: According to the study results, there is a need to strengthen rabies surveillance, promoting outbreak joint investigation, and integrated bite case management. Moreover, key messages on animal and human rabies prevention should be developed and shared with the communities. Keywords: Canine rabies, zoonoses, joint investigation, community awareness, public health, household survey

Topic: Rabies epidemiology and control
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
The Effect of 5-aza,2’-deoxyCytidine (5 AZA CdR or Decitabine) on Extrinsic, Intrinsic, and JAK/STAT Pathways in Neuroblastoma and Glioblastoma Cells Lines

5 AZA CdR can play its role through extrinsic, intrinsic, and JAK/STAT pathways to induce cell apoptosis.

Topic: Epigenetics and DNA Methylation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Myopic Loss Aversion and the Equity Premium

It uses two behavioral concepts to explain the famousequity premiumin financial markets.One is Loss Aversion meaning investors are more sensitive to loss than to gain.The other is that investors tend to evaluate their portfolios too frequently.We find that a loss averse investor who evaluate his portfolios annually will behavior in consistence with the empirical equity premium.

Topic: Financial Markets and Investment Strategies
Subfield: Finance
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Imaging and biodistribution of Her2/neu expression in non‐small cell lung cancer xenografts with <sup>64</sup>Cu‐labeled trastuzumab PET

Abstract Non‐small cell lung carcinomas (NSCLC) overexpress the Her2/neu gene in approximately 59% of cases. Trastuzumab, a humanized monoclonal antibody, interferes with Her2 signaling and is approved for the treatment of Her2/neu overexpressing breast cancer. However, its therapeutic use in Her2/neu overexpressing NSCLC remains obscure. The present study aimed to determine the role of 64 Cu‐labeled trastuzumab positron emission tomography (PET) for non‐invasive imaging of Her2/neu expression in NSCLC. Trastuzumab was conjugated with the bifunctional chelator 1, 4, 7, 10‐tetraazacyclododecane‐1, 4, 7, 10‐tetraacetic acid (DOTA) and radiolabeled with 64 Cu. The molecular specificity of DOTA‐trastuzumab was determined in NSCLC cell lines with Her2/neu overexpression (NCI‐H2170) and negative expression (NCI‐H520). Imaging of Her2/neu expression was performed in NCI‐H2170 tumor‐bearing mice with 64 Cu‐DOTA‐trastuzumab PET and 64 Cu‐DOTA‐IgG. In vitro studies revealed specific binding of DOTA‐trastuzumab in the Her2/neu positive NCI‐H2170 cells, while no binding was seen in the Her2/neu negative NCI‐H520 cell line. Biodistribution and PET studies revealed a significantly high accumulation of 64 Cu‐DOTA‐trastuzumab in the Her2/neu overexpressing NCI‐H2170 tumor at 24 h and 48 h post‐injection (21.4±1.4% and 23.2±5.1% injection dose/gram (% ID/g), respectively). PET imaging of Her2/neu negative NCI‐H520 tumors showed much less uptake of 64 Cu‐DOTA‐trastuzumab (4.0% ID/g). The NCI‐H2170 tumor uptake of 64 Cu‐DOTA‐trastuzumab was significantly higher than that of 64 Cu‐DOTA‐IgG (p&lt;0.0001). 64 Cu‐DOTA‐trastuzumab showed a very clear image of a Her2/neu positive tumor and appeared to be effective as a PET tracer for imaging of Her2/neu gene expression in NSCLC, suggesting its potential clinical use for identifying patients that might benefit from trastuzumab‐based therapy.

Topic: Radiopharmaceutical Chemistry and Applications
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Drugs and Pharmaceuticals: Safety Considerations

Man and animals are prone to a wide variety of diseases and infections. Over the centuries and decades humans suffer due to known (identifiable) and unknown (not well diagnosed) diseases and ailments, making it imperative to introduce a large number of newer and newer drugs. Very often these conditions need multiple drug therapy for effective cure. In this context, the safety and efficacy of the therapy is of immense importance. Drugs are known to possess physical and chemical incompatibilities. During the manufacturing of drugs and pharmaceutical dosage forms care should be taken to contain the ill effects. Also, complete care is necessary in handling and disposal, especially with potent drugs and the associated problems that result from their storage and packaging in pharmacies and health care industries. The present chapter deals with therapeutic incompatibilities such as drug interactions and associated toxicities, accidental or deliberate poisoning, and treatment of adverse effects in emergency in the health care industry. The understanding of the drug interactions is essential for workers because it is associated with the potentiation or alteration of therapeutic effects vis-à-vis the skills background knowledge of the personal and professionals working in the factories, store house, and the clinical industries as a whole. During the multiple drug therapy many a times one mixes two medicines of different classes and administer to the patient. Under such conditions it is possible that some of these drugs either loose their activity or rarely may have an enhanced effect. This change is known as incompatibility hence the pharmacist/doctor/nurse must use his pharmaceutical knowledge and pharmacological background, which will help an appropriate line of action. There are many reports of interactions of plastic bags, plastic syringes, aluminium needles with medicines where additives/materials of these packaging materials either reacts or leach out into the formulations. This information will help the manufacturers and packaging agents to exercise caution during the processing, packaging and storage of drugs meant for human consumption. The handling of toxic compounds such as anticancer agents, demand proper handling with protective clothing and hand gloves. Industrial pharmacists or workers should be well aware of the possible physical and physico-chemical incompatibilities and chemical incompatibilities. This chapter deals on different important aspects associated with accidental, deliberate or acute poisoning of drugs leading to adverse effects and drug abuse.

Topic: Safe Handling of Antineoplastic Drugs
Subfield: Occupational Therapy
Field: Health Professions
Domain: Health Sciences
THE IMPLEMENTATION OF MEDIA IN ENGLISH LANGUAGE TEACHING

This study which was conducted at SD Islam Laboratorium Neuhen, Mesjid Raya is intended to figure out how the implementation of media in English language teaching to the six levels. The study was conducted case study research design. The population was 44 and the sample was taken by using nonprobability sample that is convenience sampling was 22 students and 1 English teacher. The research problems are: (1) what kinds of media are used by the teacher in teaching English? (2) how does the teacher implement media in teaching English? (3) what are the obstacles faced by the teacher in teaching English by using media (4) what are students’ responses toward using media in English language teaching? The data were collected by using instruments, namely: observation checklist sheets, questionnaire sheet, interview guidelines, and documentations.Based on the data analysis, it was found that (1) the English teacher at SD Islam Laboratorium used (a) smart phone as audio media (b) visual printed media such as book, magazine and newspaper (c) visual display media such as picture, flashcard, poster, realia/model/mock up, puzzle and blackboard (d) teacher herself as model (2) the teacher did three phases in using media. They are: (a) preparation; learning curriculum and syllabus, the teacher matches the basic competences with appropriate media, preparing the media, bring the media to the class, recognizing the types of the students (b) core activity; students’ question about media, student-centered in learning process while using media, good interaction in using media, cognitive-affective-psychomotor of the student in using media (c) closing; summarization of using media, motivation/moral value of using media, giving homework. In addition the teacher did positive performance in using media (3) some difficulties faced by the teacher in the implementation of media in English language teaching, they are: designing lesson plan and preparing appropriate teaching materials as media (4) the students' responses toward the implementation of media was very positive. The findings show that 90% of the students like to study English by using media. So, it is suggested that English teacher should use the media, because they are the effective tools in English teaching-learning process.

Topic: English Language Learning and Teaching
Subfield: Information Systems
Field: Computer Science
Domain: Physical Sciences
Mental Health Literacy and Self-Stigma on Intention to Seek Professional Psychological Help

This study aims to determine the effect of mental health literacy and self-stigma on the intention to seek professional psychological help in the mental health community. Data collection using research instruments from the Mental Health Literacy Scale (MHLS), The Self Stigma of Seeking Psychology Help (SSOSH-10), and the TPB Questionnaire on Mentalhealing.id community members who joined in the application Telegram (n=100). Data were analyzed using the Multiple Linear Regression analysis. The results of this study indicated that there is a significant effect of mental health literacy and self-stigma on the intention to seek professional psychological help in the mental health community (Fvalue= 20,501; Ftable= 2.36; p&lt;0.10). The level of intention to seek professional psychological help is in a good category, which is 61%.

Topic: COVID-19 Prevention and Impact
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Quantization of causal diamonds in (2+1)-dimensional gravity -- Part I: Classical reduction

We develop the non-perturbative reduced phase space quantization of causal diamonds in (2+1)-dimensional gravity with a nonpositive cosmological constant. In this Part I we focus on the classical reduction process, and the description of the reduced phase space, while in Part II we discuss the quantization of the phase space and quantum aspects of the causal diamonds. The system is defined as the domain of dependence of a spacelike topological disk with fixed boundary metric. By solving the constraints in a constant-mean-curvature time gauge and removing all the spatial gauge redundancy, we find that the phase space is the cotangent bundle of Diff^+(S^1)/PSL(2,R), i.e., the group of orientation-preserving diffeomorphisms of the circle modulo the projective special linear subgroup. Classically, the states correspond to causal diamonds embedded in AdS_3 (or Mink_3 if $Λ= 0$), with fixed corner length, and whose Cauchy surfaces have the topology of a disc.

Topic: Black Holes and Theoretical Physics
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
Photonic synaptic system for MAC operations by interconnected vertical cavity surface emitting lasers

We report experimentally on high-speed, tuneable photonic synaptic architectures realized with vertical cavity surface emitting lasers (VCSELs) connected in series and in parallel configurations. These are able to perform the controlled weighting of fast (150 ps long) and low energy ( µ W peak power) optical pulses (or spikes), and permit high-speed (0.5 GHz) dynamic weight tunability, for the implementation of important spike processing functionalities. These include, for the in-series VCSEL synaptic architecture, the performance of accumulative weighting and, due to amplification, the compensation of losses in sequential neural network layers. Additionally, for the in-parallel VCSEL synaptic architecture, we show the system’s ability to perform key multiply and accumulate operations using fast, low-power optical spiking signals as inputs. Moreover, this work uses off-the-shelf VCSELs operating at key telecom wavelengths (1300 and 1550 nm) thus making our technique fully compatible with optical telecommunication networks and data centre technologies. These results therefore highlight the suitability of our approach for hardware-friendly, low power, high-speed and fast tuning VCSEL-based photonic synaptic architectures with excellent scalability prospects for use in future neuromorphic photonic computing systems.

Topic: Neural Networks and Reservoir Computing
Subfield: Artificial Intelligence
Field: Computer Science
Domain: Physical Sciences
Failure mechanism of solidification cracks in semiconductor laser packaging

In this work, we experimentally investigate the defect mechanisms in spot-welding technique for receptacle laser packaging. Results obtained from the stainless-to-kovar joints show that the surface cracks are eliminated by reducing the gold thickness from the kovar before welding, while the centerline cracks in the fusion zone are eliminated by the air gap tightness between the kovar and stainless. The low solubility of gold in the kovar and the large air gap between the joints are identified as the mechanisms for surface and centerline cracks, respectively. A reduction of post-weld-shift (PWS) technique in laser packaging is also presented on the basis of a detailed understanding of the welded joint quality and the defect mechanisms in the laser welding process. Preliminary reliability data demonstrated that these laser packages, which do not have hole and crack defects in the welded joints, are reliable.

Topic: Electronic Packaging and Soldering Technologies
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Swamped By Muslims: A Critical Discourse Analysis of Pauline Hanson’s Maiden Speech 2016

This article explores the recent upsurge of using prejudicial discourses in political communication. Following in the footprints of US president Donald Trump many right-wing populist politicians around the world used the strategies of fear to coerce policy making. This article examines the implicit and explicit discursive strategies that were used by Australian Senator Pauline Hanson in order to persuade policymakers to stop immigration and ban the woman's headscarf. The study involves a critical discourse analysis of the maiden speech delivered by Pauline Hanson in Parliament in 2016. The article focuses on the methodologies of Van Dijk's Ideological Square and Ruth Wodak's discourse –historical approach to inspect the linguistic devices used. The findings of the study show that Pauline Hanson used certain lexical choices to represent Australian Muslims as the 'Other' and politicized the issue to achieve her long-lasting wish of banning the immigrants.

Topic: Migration, Refugees, and Integration
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
[Insulinoma of the pancreas--difficulties with imaging].

We present a case of 29-year old man in whom despite the lack of finding tumor in USG and CT surgical intervention was performed and insulinoma of the pancreas was excised. Insulinoma was diagnosed on the basis of clinical picture (Whipple's triade) that was reassured by positive fast test. The fast was terminated at 11 and half hours because of neuroglycopenic symptoms with serum glucose and insulin levels 2.0 mmol/l (36 mg/dl) and 11.07 microU/ml respectively, which established the diagnosis. Laparotomy was performed, during which the tumor was palpated and seen in ultrasonography in the head of pancreas. The tumor of 12 mm diameter was excised. Histopathological examination revealed benign insulinoma. After surgery the symptoms alleviated completely. The patient with proper glucose levels was discharged in good health. The case supports high usefulness of intraoperative ultrasonography and surgeon's palpation.

Topic: Neuroendocrine Tumor Research Advances
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
CCDC 738747: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Frequency and antibiogram of multi-drug resistant Pseudomonas aeruginosa.

Increasing fequency of infections due to MDR Pseudomonas aeruginosa is an emerging threat in our set up which an be prevented by prescribing antibiotics judiciously and by adopting proper disinfection measures.

Topic: Antibiotic Resistance in Bacteria
Subfield: Molecular Medicine
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Application of Texture and Fractal Dimension Analysis to Evaluate Subgingival Cement Surfaces in Terms of Biocompatibility

Biocompatibility is defined as “the ability of a biomaterial, prosthesis, or medical device to perform with an appropriate host response in a specific application”. Biocompatibility is especially important for restorative dentists as they use materials that remain in close contact with living tissues for a long time. The research material involves six types of cement used frequently in the subgingival region: Ketac Fil Plus (3M ESPE, Germany), Riva Self Cure (SDI, Australia) (Glass Ionomer Cements), Breeze (Pentron Clinical, USA) (Resin-based Cement), Adhesor Carbofine (Pentron, Czech Republic), Harvard Polycarboxylat Cement (Harvard Dental, Great Britain) (Zinc polycarboxylate types of cement) and Agatos S (Chema-Elektromet, Poland) (Zinc Phosphate Cement). Texture and fractal dimension analysis was applied. An evaluation of cytotoxicity and cell adhesion was carried out. The fractal dimension of Breeze (Pentron Clinical, USA) differed in each of the tested types of cement. Adhesor Carbofine (Pentron, Czech Republic) cytotoxicity was rated 4 on a 0–4 scale. The Ketac Fil Plus (3M ESPE, Germany) and Riva Self Cure (SDI, Australia) cements showed the most favorable conditions for the adhesion of fibroblasts, despite statistically significant differences in the fractal dimension of their surfaces.

Topic: Endodontics and Root Canal Treatments
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences