jimnoneill/paper-to-field-training huggingface dataset:
Myocardial Ischemia/Reperfusion Injury in NADPH Oxidase–Deficient Mice

Abstract —Previous studies have suggested that oxygen-derived free radicals are involved in the pathophysiology of myocardial ischemia/reperfusion (MI/R) injury. Specifically, neutrophils have been shown to mediate postischemic ventricular arrhythmias and myocardial necrosis. We hypothesized that MI/R injury would be reduced in the absence (−/−) of NADPH oxidase. Heterozygous control mice (n=23) and NADPH oxidase –/– mice (n=24) were subjected to 30 minutes of coronary artery occlusion and 24 hours of reperfusion. Myocardial area at risk per left ventricle was similar in heterozygous control hearts (55±3%) and NADPH oxidase –/– hearts (61±4%). Contrary to our hypothesis, the size of infarct area at risk was similar in the heterozygous control mice (42±4%) and NADPH oxidase –/– mice (34±5%) ( P =not significant). In addition, echocardiographic examination of both groups revealed that left ventricle fractional shortening was similar in NADPH oxidase –/– mice (n=8; 27±2.5%) and heterozygous control mice (n=10; 23.3±3.3%) after MI/R. Superoxide production, as detected by cytochrome c reduction, was significantly impaired ( P &lt;0.01) in NADPH oxidase –/– mice (n=6) compared with heterozygous mice (n=7) (0.04±0.03 versus 2.2±0.08 nmol O 2 ·min –1 ·10 6 cells –1 ). Intravital microscopy of the inflamed mesenteric microcirculation demonstrated that leukocyte rolling and adhesion were unaffected by the absence of NADPH oxidase. Oyster glycogen-stimulated neutrophil transmigration into the peritoneum was also similar in both the heterozygous control mice and NADPH oxidase –/– mice ( P =not significant). These findings suggest that NADPH oxidase does not contribute to the development of myocardial injury and dysfunction after MI/R.

Topic: Cardiac Ischemia and Reperfusion
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Supplementary Results, Figure and Table Legends from Malignant Germ Cell Tumors Display Common MicroRNA Profiles Resulting in Global Changes in Expression of Messenger RNA Targets

Supplementary Results, Figure and Table Legends from Malignant Germ Cell Tumors Display Common MicroRNA Profiles Resulting in Global Changes in Expression of Messenger RNA Targets

Topic: Cancer-related molecular mechanisms research
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Klebsiella plasmid K21 is not involved in the aetiology of ankylosing spondylitis.

The possibility that a plasmid carried by Klebsiella pneumoniae plays a role in the pathogenesis of ankylosing spondylitis was explored. K. pneumoniae K21 contains a congruent to 25-kb plasmid, but this plasmid is not present in lymphocyte DNAs of ankylosing spondylitis HLA-B27 patients, as demonstrated by molecular hybridization experiments.

Topic: Spondyloarthritis Studies and Treatments
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Cortical Activations During Auditory Verbal Hallucinations in Schizophrenia: A Coordinate-Based Meta-Analysis

This meta-analysis demonstrated that experiencing AVHs is associated with increased activity in fronto-temporal areas involved in speech generation and speech perception, but also within the medial temporal lobe, a structure notably involved in verbal memory. Such findings support a model for AVHs in which aberrant cortical activations emerge within a distributed network involved at different levels of complexity in the brain architecture. Critical future directions are considered.

Topic: Hallucinations in medical conditions
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
[A probe into the origin and development of Ba Duan Jin's name and its connotation].

The earliest record of Ba Duan Jin is <i>Yi Jian Zhi</i>(, <i>Records of Yi Jian</i>) of the Song Dynasty, among which Ba Duan Jin refers to sitting Ba Duan Jin.Many Ba Duan Jin in books from Ming and Qing Dynasty, which are about nurturing vitality and preserving health, refer to the sitting Ba Duan Jin.Standing Ba Duan Jin was not called Ba Duan Jin at first. It was basically established in <i>Dao Shu</i> of the Song Dynasty, which has no specific name.At the procedure of spread, it was called "Yin Dao Jue" or "Lyu Zhen Ren An Le Ge" or "Xu Zhen Jun Yin Dao Jue" . Until the early years of Guangxu, when the <i>Yijinjing Wai Jing Tu Shuo</i> first call the standing Ba Duan Jin as Ba Duan Jin, the word Ba Duan Jin were mainly referred to standing Ba Duan Jin instead of sitting Ba Duan Jin.

Topic: Medical Research and Treatments
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Election Omnibus: Efforts to Realize Legal Certainty in General Elections in Indonesia

Constitutional Court Decision Number 85/PUU-XX/2022 explicitly states that there is no longer any difference between the Election regime and the Regional Election regime. This decision, in addition to providing legal certainty regarding which institution is authorized to resolve disputes over the results of the Regional Election, on the one hand also creates legal uncertainty itself. The legal uncertainty is regarding the extent to which the Regional Election regime is merged into the Election regime as stated in the decision, whether it is only limited to the principles of implementation and institutions authorized to resolve disputes over results or all of them. On that basis, this study aims to examine and analyze the urgency of forming an omnibus Election law in order to realize legal certainty for Elections in Indonesia. This research is a legal research using a statutory approach, conceptual approach, and case approach. The results of this study indicate that the meaning of merging the Regional Election regime into the Election regime must be interpreted as a whole. Starting from the organizing institution, the principles of implementation, to the institution authorized to resolve disputes over results. So, it is important to form what is called an omnibus Election law. This is because to realize legal certainty; To implement Constitutional Court Decision Number 85/PUU-XX/2022; and To realize a meaningful election.

Topic: Indonesian Election Politics and Participation
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
A polynomial time algorithm for computation of the Tutte polynomials of graphs of bounded treewidth

For each fixed, positive integer k we give an algorithm which decides if a given graph G has treewidth at most k and if so, it computes the Tutte polynomial of G in time O((2 n) 3+2 log 2 (c 1 )= log 2 ( 5 4 ) ), where c1 is twice the number of partitions of a set with 3 k +3 elements. The decision if G has treewidth at most k can be obtained in linear time due to an algorithm of H. Bodlaender.

Topic: Advanced Graph Theory Research
Subfield: Computational Theory and Mathematics
Field: Computer Science
Domain: Physical Sciences
Varietal Identification and Seed Quality Estimation through Biochemical Characterisation of Amaranth (Amaranthus hypochondriacus L.)

The present investigation was conducted during kharif of 2021 at College of Forestry, Ranichauri, Tehri Garhwal of VCSG Uttarakhand University of Horticulture &amp; Forestry, Bharsar, Pauri, Garhwal, Uttarakhand, to investigate the biochemical characteristics of different varieties of amaranth.The laboratory experiment was conducted in completely randomized design (CRD) with three replications comprising seven varieties to assess the seed quality and biochemical characters of grain amaranth.In laboratory condition, the seed quality attributes under standard germination test ,viz., germination percentage, seedling total length, seedling fresh and dry weight,and seedling vigour indices were recorded higher with the treatmentT5(PRA-2).Under stress test,viz., accelerate ageing, cold test and water sensitivity test, significantly higher value of seed quality parameters were recorded with the treament T6(PRA-3).On the basis of this investigation, it could be concluded that treatments T4 (PRA-1), T5(PRA-2), T6(PRA-3) and T7(Annapurna)are performing overall better for biochemical and seed quality of amaranth.

Topic: Seed and Plant Biochemistry
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
CCDC 1557698: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Far from Houdini: The ‘Magic’ of the VFX Breakdown

VFX (visual effects) breakdowns are short ancillary videos that advertise the digital animation work undertaken by a VFX company for a particular film or television programme. Claiming to take viewers ‘behind the magic’ of VFX, breakdowns disassemble a wide variety of shots and sequences, and point to the extensive use of computer-generated imagery in contemporary blockbuster cinema. But, as much as breakdowns reveal some illusions, they conjure others. Breakdowns operate in a register of speed, fluidity and efficacy, showing neither the many people nor the extensive periods of time that it takes to painstakingly generate all these VFX. In this article, the author reveals how the omission of labour and duration in VFX breakdowns both reflects and contributes to a broader (mis)understanding of digital effects as immaterial, instantaneous and magical. His case study is Spider-Man: Far From Home (2019), a film that links VFX with magic, evokes the breakdown in some of its spectacular visuals, and even outright villainizes those effects artists who seek fair recognition for their work.

Topic: Cinema and Media Studies
Subfield: Economics and Econometrics
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Process optimization tweaking tool (POTT) and its application in controlling oxidation thickness

This computer utility extracts process data from a manufacturing statistical process control database, calculates oxidation times appropriate to recenter the thickness to the desired process mean, and inserts the values of new oxidation times directly into furnace oxidation recipes resident in the main BTU host computer so that production furnace recipes downloaded to the furnace controller automatically contain the new oxidation times. The major attributes of POTT are summarized and its application in controlling oxidation thickness for silicon integrated-circuit fabrication as well as results obtained using two different retargeting strategies are described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>

Topic: Industrial Vision Systems and Defect Detection
Subfield: Industrial and Manufacturing Engineering
Field: Engineering
Domain: Physical Sciences
Notes On Two Original Metres

This is a letter I sent out as dated. I can't find the enclosure, and can't remember to whom I sent it, although I have a feeling that at some point I sent a copy to the World Order Of Narrative Poets (ie one man and his dog in New York). Such vanity!

Topic: Single-cell and spatial transcriptomics
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Identifiability and identification of a class of parabolic distributed systems under approximation

The identifiability and identification problem of linear distributed parameter systems is studied. A parabolic distributed parameter system is approximated into a finite-dimensional model using orthogonal polynomials. The identifiability problem of the lumped model is studied. Then the problem of estimating the parameters of the finite-dimensional model is investigated, and the local uniqueness of the identified values is discussed. An illustrative example is given and good results are obtained.

Topic: Numerical methods in inverse problems
Subfield: Mathematical Physics
Field: Mathematics
Domain: Physical Sciences
Comparative Analysis of Software Complexity of Searching Algorithms Using Code Based Metrics

Software complexity metrics are used to quantify a variety of software properties. Complexity measures can be used to predict critical information about testability, reliability and maintainability of the software systems from automatic analysis of the source code. In this paper different software complexity metrics were applied to searching algorithms, our intention is to compare software complexity of linear and binary search algorithms, evaluate, rank competitive object oriented applications (Visual Basic, C#, C++ and Java languages) of these two algorithms using code based complexity metrics such as (line of codes, McCabe cylomatic complexity metrics and Halstead complexity metrics) and measured the sample programs using length (in lines) of the program, line of code (LOC) without comments, LOC with comments, McCabe method, the program difficulty using Halstead method. The result revealed that McCabe method has negligible values of complexity for Visual Basic, C#, C++ and Java languages for linear search and similar measuring values for binary search and also from statistical analysis of ANOVA (Analysis of Variance) the result showed that for both linear and binary search techniques, the four (4) languages do not differ significantly, therefore it is concluded that any of the four (4) programming languages is good to code linear and binary search algorithms.

Topic: Software Engineering Research
Subfield: Information Systems
Field: Computer Science
Domain: Physical Sciences
Cardiac transplantation in Hawai'i: a summary of the first 21 years.

Between 1987 and 2008, 45 patients have undergone cardiac transplantation in Hawai'i. This article summarizes the authors' experiences with cardiac transplantation over this 21-year period. The cumulative 1-, 3- and 5-year survival rates after transplantation have been 73.8%, 70.0%, and 63.2%, respectively. The corresponding survival rates have improved over the last eight years and are now 90.0%, 87.5%, and 83.3%, respectively. Despite clinical improvements, low patient volumes make the maintenance of a state-based program in Hawai'i difficult. Problems with financing and referral biases will need to be addressed if a local program is to continue.

Topic: Transplantation: Methods and Outcomes
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Wages and Employment in a Random Social Network with Arbitrary Degree Distribution

Empirical studies of labor markets show that social contacts are an important source of job-related information [Ioannides and Loury (2004)]. At the same time, wage differences among workers may be explained only in part by differences in individual background characteristics. Such findings motivate our model in which differences in "social connectedness" among otherwise identical workers result in wage inequality and differences in unemployment rates. The paper is related to theoretical contributions by Calvo- Armengol and Jackson (2004) and Calvo-Armengol and Zenou (2005) and builds on the Pissarides (2000) model. Workers may hear about job openings directly from employers or through their social contacts. We go further by introducing heterogeneity in the number of contacts each worker has with others, i.e. in the workers' degree. We utilize results from the technical literature on random graphs with arbitrary degree distributions [Newman, (2003a)] to account for a consequence of workers' receiving information about job openings from their social contacts: they compete with their social contacts' other contacts. For social networks with arbitrary degree distributions we show that people who are better connected receive a higher wage on average and face a lower unemployment rate. Numerical computations for the specific case in which connections follow a Poisson distribution show that variability in connections can result in substantial variation in the above labor market outcomes.

Topic: Game Theory and Applications
Subfield: Management Science and Operations Research
Field: Decision Sciences
Domain: Social Sciences
Exploring the Clinical Signatures of Cervical Dysplasia Patients and Their Association With Vaginal Microbiota

ABSTRACT Aims The vaginal microbiota plays a crucial role in women's health, and an imbalanced vaginal microbiota is linked to various diseases, including human papillomavirus (HPV) infection. However, most available data comes from Western countries and primarily focuses on HPV infection, with only a few studies considering detailed clinical factors to explore the relationship between vaginal microbiota and the development of cervical cancer, especially in China. Materials and Methods Our study involved 266 women, including individuals at all stages of cervical dysplasia, and healthy controls with and without HPV infection. We assessed several aspects of the vaginal environment, including vaginal microbiota composition using 16S rRNA gene sequencing, HPV infection status using the standard Roche Cobas method, pH value, age, and H 2 O 2 levels from clinical records, and partner numbers and contraceptive methods obtained through questionnaires. The association of these clinical signatures with cervical dysplasia stages and vaginal microbiota was analyzed. Key Findings Our findings demonstrate a significant association between vaginal microbiota and cervical dysplasia stages. Patients with cervical dysplasia and cancer showed a substantial increase in HPV 16 infection, a higher prevalence of pH &gt; 5, a lower H 2 O 2 level, and older ages compared to healthy individuals. Additionally, these factors influence the beta diversity of the vaginal microbiota. Significance These results underscore the importance of considering the vaginal microbiota within the cancer microenvironment and highlight the need to integrate all available data to aid in the current diagnosis and understanding of cervical dysplasia and the cervical cancer microenvironment.

Topic: Reproductive tract infections research
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
A Study on the Relationship between Attachment, Social Competence, and Emotion Regulation

This study investigated the structural relationships between attachment, social competence, and emotion regulation. A survey was administered to 233 children of elementary school age(5th-6th grades) in G-city, Korea, using the IPPA-R, the Social Competence Inventory and an Emotion Regulation Scale. The collected data were then analyzed using a Canonical Correlation Analysis. First, the relationship between attachment and social competence was analyzed. The results showed that attachment and social competence have a positively correlated relationship. Peer attachments strongly affect the attributes of social competence when using a canonical variate analysis. Secondly, the relationship between attachment and emotional regulation was analyzed. The results showed that attachment and emotion regulation are also positively correlated. Maternal attachment particularly strongly affected the attributes of emotion regulation. Thirdly, the relationship between social competence and emotional regulation was analyzed. The results showed that social competence and emotional regulation have a positive relationship.

Topic: Attachment and Relationship Dynamics
Subfield: Social Psychology
Field: Psychology
Domain: Social Sciences
Roles of the Bloom's syndrome helicase in the maintenance of genome stability

The RecQ family of DNA helicases is highly conserved in evolution from bacteria to humans. Of the five known human RecQ family members, three (BLM, WRN and RECQ4, which cause Bloom's syndrome, Werner's syndrome and Rothmund–Thomson syndrome respectively) are mutated in distinct clinical disorders associated with cancer predisposition and/or premature aging. BLM forms part of a multienzyme complex including topoisomerase IIIα, replication protein A and a newly identified factor called BLAP75. Together, these proteins play a role in the resolution of DNA structures that arise during the process of homologous recombination repair. In the absence of BLM, cells show genomic instability and a high incidence of sister-chromatid exchanges. In addition to a DNA structure-specific helicase activity, BLM also catalyses Holliday-junction branch migration and the annealing of complementary single-stranded DNA molecules.

Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Developing a Program Model for School-Based Day Treatment for Social, Emotional, and Behavioral Difficulties

School-based day treatment is an intensive mental health service for children with social, emotional, and behavioral difficulties. Research on day treatment is scarce and descriptions of program models are lacking. We used stimulated recall interviews to explore the moment-to-moment processes and strategies of classroom staff in a day treatment program for children in kindergarten and Grade 1 in Canada. Several processes and strategies used by staff emerged from the thematic analysis of the interviews. These included a process of individualized intervention, characterized by a continual and cyclical process of attunement, responsiveness, assessment, and evaluation, using a team-based approach, noticing positives about children, a climate of positive relationships, staff regulating their own emotions, being flexible while also being firm and consistent, and seeing children from a developmental perspective. More specific strategies used by staff (e.g., token economy) also emerged from the interviews. Implications for future research and teacher training are discussed.

Topic: Child and Adolescent Psychosocial and Emotional Development
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
A quickscan pest risk analysis for the Meloidogyne mali

A quickscan pest risk analysis for the apple root-knot nematode Meloidogyne mali for the territory of Ukraine was performed. This assessment was initiated in response to the recent (2012/2013) interception of the apple root-knot nematode in the Netherlands and Italy and because of the species inclusion on the EPPO Alert List in 2014. The risk of M. mali introduction, establishment and economic impact in Ukraine was assessed as likely, which proved the need for specific statutory actions to be taken to prevent ingress of the apple root-knot nematode and mitigate its effects in Ukraine. It is stated that the detailed pest risk analysis is required.

Topic: Nematode management and characterization studies
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences