jimnoneill/paper-to-field-training huggingface dataset:
Intelligent content management in e-commerce websites: Creating an intelligent content management to have intelligent customer relationship management in e-commerce websites

Seller and buyer are present in physical relationships between humans and their interactions to perform business dealings, so the seller can make relation with customer to know his needs by using customer management sciences and psychologies necessary for understanding customer needs. The most important and difficult part of the sales is to identify customer needs and they are not well known, but to identify the customer itself. Customer identification in terms of tastes, personality and psychology are as important as understanding of his /her needs. When the seller knows his/her customers, even the kind of deal between them takes a special form. Identify the customer and his/her needs lead to satisfy his/her needs at best. It has a completely unconscious impact on increasing customer confidence. When the customer confidence increases, its effect on his/her loyalty can be felt. The ultimate goal of any business is customer loyalty. The thesis tries to create intelligent and targeted management in websites content by intelligent agents. The aim of management is to create customer relationship management which establishes an intelligent relationship to identify the customer and to continue to keep and improve customer confidence by specific marketing techniques and to make loyalty in customer. As mentioned before, customer loyalty is the ultimate goal of any business. The thesis tries to create an intelligent business website so that it begins with bilateral interaction between the customer and the web. Web content will take an action to identify the customer by intelligent agents for customer relationship management science and continue its management to complete web customer process.

Topic: Customer churn and segmentation
Subfield: Marketing
Field: Business, Management and Accounting
Domain: Social Sciences
Supplementary Figure 2 from &lt;i&gt;NOTCH&lt;/i&gt; Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer

Supplementary Figure 2 from &lt;i&gt;NOTCH&lt;/i&gt; Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer

Topic: Cancer Research and Treatments
Subfield: Biotechnology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
UM-164, a Dual Inhibitor of c-Src and p38 MAPK, Suppresses Proliferation of Glioma by Reducing YAP Activity

UM-164 is a dual inhibitor of c-Src and p38 MAPK, and has been a lead compound for targeting triple-negative breast cancer. UM-164 shows stronger binding to the active sites of Src compared with the conventional Src inhibitor Dasatinib. While Dasatinib has displayed some inhibitory effects on glioma growth in clinical trials, whether UM-164 can suppress glioma growth has not been reported. Here we show that UM-164 suppressed the proliferation, migration and spheroid formation of glioma cells, and induced cell cycle arrest in the G1 phase. Moreover, UM-164 triggered YAP translocation to the cytoplasm and reduced the activity of YAP, as evidenced by a luciferase assay. Accordingly, UM-164 markedly decreased the expression levels of YAP target genes CYR61 and AXL. Importantly, ectopic expression of wild-type YAP or YAP-5SA (YAP constitutively active mutant) could rescue the anti-proliferative effect induced by UM-164. Intriguingly, p38 MAPK appears to play a greater role than Src in UM-164-mediated inhibition of YAP activity. Furthermore, the in vitro anti-glioma effect mediated by UM-164 was confirmed in a xenograft glioma model. Together, these findings reveal a mechanism by which UM-164 suppresses the malignant phenotypes of glioma cells and might provide a rationale for UM-164-based anti-glioma clinical trials.

Topic: Hippo pathway signaling and YAP/TAZ
Subfield: Cell Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Effect of tobramycin on urinary gamma-glutamyltransferase activity: Studies in a case of renal carcinoma.

Abstract Gamma-Glutamyltransferase activity was studied in a man presenting with recurrent septicemia owing to pyonephrosis and renal carcinoma. Increased activity in the urine was ascribable to administration of the aminoglycoside antibiotic, tobramycin. That the renal carcinoma did not contribute to the increased values was confirmed by homogenization and enzyme histochemistry of the tumor. Although the activity of this enzyme in serum was greater than normal, this persisted postoperatively, and thus was not related to the renal carcinoma.

Topic: Amino Acid Enzymes and Metabolism
Subfield: Biochemistry
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Melatonin and TGF-β-Mediated Release of Extracellular Vesicles

The immune system, unlike other systems, must be flexible and able to “adapt” to fully cope with lurking dangers. The transition from intracorporeal balance to homeostasis disruption is associated with activation of inflammatory signaling pathways, which causes modulation of the immunology response. Chemotactic cytokines, signaling molecules, and extracellular vesicles act as critical mediators of inflammation and participate in intercellular communication, conditioning the immune system’s proper response. Among the well-known cytokines allowing for the development and proper functioning of the immune system by mediating cell survival and cell-death-inducing signaling, the tumor necrosis factor α (TNF-α) and transforming growth factor β (TGF-β) are noteworthy. The high bloodstream concentration of those pleiotropic cytokines can be characterized by anti- and pro-inflammatory activity, considering the powerful anti-inflammatory and anti-oxidative stress capabilities of TGF-β known from the literature. Together with the chemokines, the immune system response is also influenced by biologically active chemicals, such as melatonin. The enhanced cellular communication shows the relationship between the TGF-β signaling pathway and the extracellular vesicles (EVs) secreted under the influence of melatonin. This review outlines the findings on melatonin activity on TGF-β-dependent inflammatory response regulation in cell-to-cell communication leading to secretion of the different EV populations.

Topic: Circadian rhythm and melatonin
Subfield: Endocrine and Autonomic Systems
Field: Neuroscience
Domain: Life Sciences
Prognosis of Patients Listed for a Heart Transplant During the Pretransplant Period: Does Diabetes Matter?

Whether patients with advanced heart failure and diabetes mellitus (DM) should be listed for heart transplantation (HTx) remains controversial due to conflicting findings regarding their post-HTx survival (1–3). We studied HTx candidates with and without DM during the pre-HTx period, examining multiple waiting list outcomes. Patients were enrolled in the Waiting for a New Heart Study, a multisite observational study of 318 adult (≥18 years of age) patients (aged 53 ± 11 years; 18% female) who were newly listed for HTx with Eurotransplant between April 2005 and December 2006 (4). Informed consent and ethics approval were obtained (4). Characteristics at the time of listing included age, DM, and the Heart Failure Survival Score (1). Outcomes were mechanical circulatory support (MCS) device implantation, death combined with delisting due to clinical deterioration, high urgency HTx, and elective HTx.

There were 288 patients (75 with DM, 213 without …

Topic: Transplantation: Methods and Outcomes
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Return Migration among Elderly, Chronically Ill Bosnian Refugees: Does Health Matter?

Elderly migrants constitute a considerable share of global return migration; nevertheless, literature on the health aspects of the return migration among these migrants is still scarce. This study explores the significance of return migration among elderly, chronically ill Bosnian refugees from Denmark and the role of health issues in their decision to return. It is based on semi-structured interviews with 33 elderly, chronically ill Bosnian refugees who have moved back to Bosnia and Herzegovina, and 10 elderly, chronically ill Bosnian refugees who have remained in Denmark. The interviews show that physical health, in the sense of the absence of illness and easy access to necessary health-care services and medicines, was not highly prioritized when the decision was made whether or not to return. However, if health is regarded more broadly as involving more than mere physical health and the absence of illness, health did matter. Viewed as physical, social and mental well-being in line with WHO’s definition of health, health was indeed one of the most important factors when the decision to return was made.

Topic: Migration, Health and Trauma
Subfield: Clinical Psychology
Field: Psychology
Domain: Social Sciences
System Architecture For High Speed Sorting Of Potatoes

This paper illustrates an industrial application of vision processing in which potatoes are sorted according to their size and shape at speeds of up to 40 objects per second. The result is a multi-processing approach built around the VME bus. A hardware unit has been designed and constructed to encode the boundary of the potatoes, to reducing the amount of data to be processed. A master 68000 processor is used to control this unit and to handle data transfers along the bus. Boundary data is passed to one of three 68010 slave processors each responsible for a line of potatoes across a conveyor belt. The slave processors calculate attributes such as shape, size and estimated weight of each potato and the master processor uses this data to operate the sorting mechanism. The system has been interfaced with a commercial grading machine and performance trials are now in progress.

Topic: Industrial Automation and Control Systems
Subfield: Control and Systems Engineering
Field: Engineering
Domain: Physical Sciences
Effects of Walking on Accelerated Plethysmogram in Middle-aged and Elderly Women.

1日の平均歩数が中高年女性の末梢循環機能に及ぼす影響について検討することを目的として行った。対象は, 平成5～7年に肥満予防教室や糖尿病予防教室等を受講した中高年女性58名であった。受講中の1日の平均歩数が8, 000歩以上であった者をA群 (61.7±6.1歳) , 7, 000歩代であった者をB群 (60.8±6.0歳) , 7, 000歩未満であった者をC群 (65.1±2.5歳) とし, 教室前後で比較を行った。末梢循環機能の評価は, 加速度脈波計を用いて右手第2指の指尖部にて測定した。得られた波形をA～Gに分類, また算出された加速度脈波形数 (APG-Index) を採用した。その結果, すべての群において教室前後で体重, BMIの低下がみられた。A群ではHDLCの増加とFBSの低下がみられ, B群では最大酸素摂取量の増加とSBP, TC, LDL-Cの低下がみられた。A・B群では, 教室後に加速度脈波の波形タイプの改善がみられ, さらに加速度脈波形数の増加もみられた。以上の結果から, 1日7, 000歩, またはそれ以上の歩行により, 中高年女性における末梢循環機能の改善が可能であることが示唆された。

Topic: Physical Activity and Health
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Identification of Common Subpopulations of Non-Sorbitol-Fermenting, β-Glucuronidase-Negative <i>Escherichia coli</i> O157:H7 from Bovine Production Environments and Human Clinical Samples

ABSTRACT Non-sorbitol-fermenting, β-glucuronidase-negative Escherichia coli O157:H7 strains are regarded as a clone complex, and populations from different geographical locations are believed to share a recent common ancestor. Despite their relatedness, high-resolution genotyping methods can detect significant genome variation among different populations. Phylogenetic analysis of high-resolution genotyping data from these strains has shown that subpopulations from geographically unlinked continents can be divided into two primary phylogenetic lineages, termed lineage I and lineage II, and limited studies of the distribution of these lineages suggest there could be differences in their propensity to cause disease in humans or to be transmitted to humans. Because the genotyping methods necessary to discriminate the two lineages are tedious and subjective, these methods are not particularly suited for studying the large sets of strains that are required to systematically evaluate the ecology and transmission characteristics of these lineages. To overcome this limitation, we have developed a lineage-specific polymorphism assay (LSPA) that can readily distinguish between the lineage I and lineage II subpopulations. In the studies reported here, we describe the development of a six-marker test (LSPA-6) and its validation in a side-by-side comparison with octamer-based genome scanning. Analysis of over 1,400 O157:H7 strains with the LSPA-6 demonstrated that five genotypes comprise over 91% of the strains, suggesting that these subpopulations may be widespread.

Topic: Escherichia coli research studies
Subfield: Endocrinology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Key Design Characteristics for Developing Usable E-Commerce Websites in the Arab World

This research aims to suggest key design characteristics that are necessary for developing usable e-commerce websites in the Arab world. A comprehensive usability evaluation of four leading Arab e-commerce websites was conducted using the heuristic evaluation method. The results identified major and minor usability problems and major and minor good design characteristics on the selected websites. Based on the results, 51 key design characteristics were suggested. The recommended key design characteristics comprised two levels according to their priority: level one which includes mandatory key design characteristics and level two which includes supplementary design characteristics. The key design characteristics in each level were categorized under specific pages and areas that can be found on any e-commerce website. Such categorizations could direct website evaluators and designers to important pages and areas that should be considered to improve the overall usability of e-commerce websites. The results of this research are particularly important to developing countries which are still facing challenges that may affect the design and accessibility of usable and useful websites. These relate to low speed of accessing the Internet and a lack of website designers who have experience in customers’ needs and websites’ usable design characteristics.

Topic: Technology Adoption and User Behaviour
Subfield: Information Systems and Management
Field: Decision Sciences
Domain: Social Sciences
The Impact of School Heads’ Technology Leadership on Teachers’ Technological Proficiency and Academic Optimism

The adoption, integration, and use of technology in the classroom should be planned by school leaders and teachers, who should also arm themselves with the newest technological developments. This study was designed to determine the impact of school heads’ technology leadership to teachers’ instructional innovation and academic optimism during the COVID-19 period. The study utilized a quantitative research design and a descriptive-correlational research method and was confined among 31 school heads and 651 teachers in Candelaria East and West Districts during the S.Y. 2021-2022. The survey-questionnaire, which was developed by the researcher and validated by research practitioners and experts, was the primary data gathering tool. From the findings, it was deduced that there is no significant difference between the perception of the elementary and secondary teachers on the school head’s technology leadership, teachers’ technological proficiency, and teachers’ academic optimism. It revealed that the social, legal, and ethical issues; and the leadership and vision significantly predict the teachers’ technological proficiency while the social, legal, and ethical issues; leadership and vision; productivity and professional practice and support; and management, operations, and finance significantly predict the teachers’ academic optimism. In light of the findings and conclusion, the study recommends that DepEd may include the nature and concept of digital citizenship in school management and leadership.

Topic: Technology-Enhanced Education Studies
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Circulating bilirubin and defense against kidney disease and cardiovascular mortality: mechanisms contributing to protection in clinical investigations

Unconjugated bilirubin is an endogenous circulating antioxidant, bound to albumin, and therefore is retained in the vascular compartment. Bilirubin has well-documented neurotoxic effects in infants; however, current evidence indicates mildly elevated bilirubin is associated with protection from cardiovascular disease and all-cause mortality in adults. Recent clinical studies show mildly elevated bilirubin is associated with protection from kidney damage and dysfunction, in addition to cardiovascular events and all-cause mortality in patients undergoing hemodialysis. This is the first review to examine the clinical evidence and summarize the potential mechanisms of action that link bilirubin to protection from kidney damage, subsequent kidney failure, and dialysis-related mortality. With this understanding, it is hoped that new therapies will be developed to prevent renal dysfunction and mortality from cardiovascular disease in at-risk individuals.

Topic: Heme Oxygenase-1 and Carbon Monoxide
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Celebrations, Exaltations and Alpha Lands: Everyday geographies of the far-right

There is a gap in research that considers, and spatializes, the everyday geographies of far-right encounters, socialization, recreation and leisure. While much research considers the end-stages of right-wing radicalisation and focuses on the extreme right (e.g., hate groups, fringe political parties, despotic leaders, specific eruptions and episodes of violence or terror, online rhetoric), the daily processes, moments and spatial configurations in-between the mainstream and extreme are sometimes overlooked. These are crucial to understand, in order to develop a more nuanced and effective language in recognizing, responding to, and combatting right-wing radicalisation. This paper thus addresses the geographical blind spot by spatializing the everyday life of the far-right, through a three-pronged taxonomy. Drawing from ethnographic observations and social media and socio-demographic analyses, the paper argues that three geographies in particular emerge as nodes of far-right formation (attached to specific sites and online/offline): a) spaces of recreation and leisure ("Celebrations"); b) spaces of faith and spirituality ("Exaltations"); and c) spaces of the corporeal ("Alpha Lands"). These spaces intersect, extend across urban, peri-urban and rural terrains, and do not necessarily adhere to established political or territorial borders and boundaries, but rather, can be envisioned as multi-scalar spatial fixes, laden with political possibilities.

Topic: Populism, Right-Wing Movements
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
The Erotic Charisma of Alexander Hamilton

As an outsider with a mysterious childhood, Alexander Hamilton is, as psychologists say, a good “hook” for a projective identification. For his admirers Hamilton is a source of political capital. His ideas and proposals about the debt, protectionism, and an American manufacturing base are in the news in the early twenty-first century. Although the Old Left saw Hamilton as an elitist, possibly a monarchist, and a promoter of industrial capitalism, contemporary American progressives have called attention to his explicit support for habeas corpus, his efforts on behalf of banking, and his surprisingly enlightened attitudes about race and slavery. As one of the founders of a new republic, Hamilton knew he would be in the history books, but his image, representations of his physical presence, and speculation about his private life circulate on the Internet in ways that would surely astonish him. Alexander Hamilton not only has admirers in the fields of politics and history; he also has fans.

Topic: American Constitutional Law and Politics
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
Introducing the Concept of Performance Support Using the Performance Pyramid

Abstract Organizations today face social, competitive, and technological conditions unlike they have seen before. Within this complex environment, managers and team leaders must get the highest levels of performance from a diverse mix of individuals and groups. Achieving this goal requires a range of performance support strategies and resources that can be applied to various situations. This paper outlines a comprehensive model of performance support that integrates a set of factors leading to optimal performance and significant accomplishments. Referred to as the Performance Pyramid, the model has been an effective means of introducing the notion of performance support to individuals unaccustomed to thinking outside of a training paradigm. Using this model, continuing educators can offer a comprehensive program that focuses on enhancing worker performance to address the needs of their business and agency partners.

Topic: Human Resource Development and Performance Evaluation
Subfield: Applied Psychology
Field: Psychology
Domain: Social Sciences
ChemInform Abstract: New Trends in Heterogeneous Catalysis Processes on Metallic Clusters from Synchrotron Radiation and Theoretical Studies

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Topic: Advanced Chemical Physics Studies
Subfield: Atomic and Molecular Physics, and Optics
Field: Physics and Astronomy
Domain: Physical Sciences
The status and prospects for genetically modified food in Europe and Croatia

In the last sixteen years worldwide production of genetically modified (GM) crops has been increased sharply. At the same time, consumer?s attitudes toward food products made from GM ingredients have been largely negative. This review considers the global production of GM plants in 2011 and consumer attitudes towards genetically modified foods in Europe and Croatia. While planted areas of GM crops grow worldwide, data from European surveys shows generally negative consumer?s perception towards GM food. Eurobarometer survey from 2010 was especially pointed out, where Croatian consumers were included in research for first time. It has been shown that the Croatian, even more than Europeans, do not approve the use of genetically modified food in human consumption. This aversion to GM crops is based on the personal attitude of consumers, whereas the two main risks cited are: potential health risk and preference for natural food, and social risks which include possible adverse effects of GM plants on the environment. Research has shown that the perceived level of risk by consumers can be mitigated if the confidence is built in state institutions and scientific research.

Topic: Genetically Modified Organisms Research
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences