jimnoneill/paper-to-field-training huggingface dataset:
CCDC 740027: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Supplementary Figures and Legends from Semaphorin 4C Promotes Macrophage Recruitment and Angiogenesis in Breast Cancer

&lt;p&gt;S1. Apoptosis detected by TUNEL in MDA-MB-231 cells expressing shSEMA4C or EV. S2. Sema4C cDNA re-expressed in these MDA-MB-231 siSEMA4C cells could recover cell growth and ANG and CSF secretion. S3. Expression of senescence-associated pathway proteins in MDA-MB-231 cells were examined using western blot post-transfection at the indicated time. S4. SEMA4C regulates angiogenesis. S5. The vascular integrity was detected in EV tumours and shSEMA4C tumours. S6. Sections from tumors were immunostained with anti-cd45 (white arrowhead) or F4/80(black arrow) antibody. S7. SEMA4C regulates macrophage recruitment. S8. The vascular density and macrophage area were detected in EV tumours and shSEMA4C tumours at the same weight. S9. Recombinant soluble Sema4C did not affect MDA-MB-231 proliferation and endothelial cells tube formation despite could increase macrophages migration. S10. mRNA levels of ANG and CSF were analyzed in presence of siSEMA4C RNA or sema4C cDNA in MDA-MB-231cells. S11. Expression of mRNA(A) and secreted protein(B) level of ANG and CSF-1 were detected in the MCF-7 cells overexpressing SEMA4C. S12. The growth curve and cell cycle were detected in presence of siANG in MDA-MB-231 cells.&lt;/p&gt;

Topic: Axon Guidance and Neuronal Signaling
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Physico-Chemical Properties of Cationic Derivatives of the Anti-Inflammatory Drug, , β-Glycyrrhizinic Acid

The anti-inflammatory drug, β-glycyrrhizinic acid 20-methyl ester (GMe), was converted to cationic variants (CGRs) by derivatizing diglucronic carboxyl groups with 2- (N-ethyl-, N-butyl- and N-benzyl-N, N-dimetylammonio) ethylamines. Critical micellar concentrations, ranging from 0.40.7mM, were essentially independent of solution pH from 5 to 9 and approximated that of GMe (0.3mM at pH 57.4). Transferability (%) of CGRs from water to 1-octanol phase at higher-than-neutral pH was much more than that of GMe or β-glycyrrhizinic acid (GL) : CGBu (55) >CGBn (20) >CGEt (15) >GMe (10) >GL (0). CGRs remarkably accelerated the release of the carboxyfluorescein (CF) trapped inside DPPC vesicles with no costing significant damage to cell membranes. The CF-releasing mechanism was examined kinetically by differential scanning calorimetory, light-scattering and electron microcopy.

Topic: Pharmacological Effects of Natural Compounds
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
Le Candi Badut

Jacques Dumarçay Candi Badut, in the Malang region in East Java, was built in the second half of the 8th c. It was subsequently transformed over a long span of time up to the 1 3th c. as it was adapted to successive changes of rituals. The observation of these transformations shows the role of architecture in the ritual life of temples, but also the liberty of builders towards the religious symbolism of the buildings.

Topic: Architectural and Urban Studies
Subfield: Conservation
Field: Arts and Humanities
Domain: Social Sciences
Empirical Modeling of Metal-Contact Effects on Graphene Field-Effect Transistors

An empirical model is developed to characterize metal-contact effects on the transfer characteristics of graphene field-effect transistors. The present model is based on a diffusive transport, and considers charge carrier doping from metallic electrodes to the adjacent graphene channel. An electron–hole conductivity asymmetry, one of the main features in the transfer characteristics, is well reproduced by the model. Model calculations with varied parameters show that the conductivity asymmetry becomes more distinct with higher charge-carrier mobility, higher doping level at the metal contacts, larger extent of the doped region near the contacts, or shorter channel lengths.

Topic: Graphene research and applications
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Transnational migration, gender and educational development of children in Tajikistan

Abstract In Tajikistan, a Central Asian country with high rates of emigration, there is little systematic empirical research on the education of children in transnational households. In this study, I use national representative data from 2011 to examine the number of years lag in education of boys (N=1110) and girls (N=1140) aged 7 to 17 who live in different transnational care arrangements compared with those living in non‐migrant households. I demonstrate that being in a transnational household reduces the risk of an educational lag, although there are gender differences when measuring this relationship. In particular, girls are less likely to have an educational lag if the mother or both parents migrate, if the duration of parental absence is shorter rather than longer, and if migrants send remittances home. The legal status of parents abroad and maternal migration are advantageous for boys’ education. These findings highlight the importance of looking at complex transnational forms of living and at gender when assessing the educational outcomes of children in migrant sending contexts.

Topic: Migration and Labor Dynamics
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Beer Fluorescence and the Isolation, Characterisation and Silica Adsorption of Haze-Active Beer Proteins

The fluorescence spectra and lifetimes of diluted beer have been explored and found not to report on protein removal either by silica or tannic acid, nor polyphenol uptake by PVPP. Comparing the fluorescence spectra of beer with that of tea and hops, it seems that proteins, complex polyphenols and iso-α-acids can contribute to the intrinsic fluorescence of beer, although the contribution from polyphenols must be minimal since treatment with PVPP does not dramatically change the background fluorescence. To eliminate the problem of background fluorescence haze-active protein was isolated. Steady-state and time-resolved fluorescence techniques were used to characterise these and to monitor their uptake by different silica gels as a function of pH. Heat treated large pore volume, small surface area silicas were the more effective adsorbers for the proteins under study, with pH 4 being optimum. Using both intrinsic amino acid fluorescence and the extrinsic fluorophore fluorescamine, the time-resolved fluorescence anisotropy has been measured and the radius of the isolated haze protein found to be ∼ 35 Å. Comparisons have been made with proteins of known size and structure such as human and bovine serum albumins (HSA and BSA).

Topic: Fermentation and Sensory Analysis
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
[Complications of laparoscopic gastrectomy for gastric cancer and the management].

In recent years, laparoscopic gastrectomy has developed rapidly for both early and advanced gastric cancer. Most studies showed that the operative complication rate is comparable between laparoscopic and open surgery. The common complications related to laparoscopic gastrectomy are anastomotic leakage, stenosis, intra-abdominal bleeding, pancreatic leakage, bowel obstruction, etc. This article provides insights into the reasons, classification, management, and prevention of the complications related to laparoscopic gastrectomy.

Topic: Gastric Cancer Management and Outcomes
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Acaseofacutecompartmentsyndromeof thelegfollowingprolongedlithotomyposition duringurologicalsurgery ChetanPrakash,AbdullahABonajmah,AmroAhmed CASE REPORT OPEN ACCESS

� � � � � � � � � � � � � � � � ABSTRACT � Introduction: Acute compartment syndrome (ACS) is an orthopedic emergency which if not recognized and treated in time can lead to serious irreversible damage to neuromuscular structures. Case Report: We are reporting here a case of acute compartment syndrome of the right leg in an adult male patient following a prolonged urological surgery of five hours in the lithotomy position. Post-operatively the patient's signs and symptoms were diagnosed early and an urgent fasciotomy was done which relieved him of his symptoms and averted major damage to his leg. Conclusion :�Acute compartment syndrome of the leg is a recognized but rare iatrogenic complication in many prolonged urological procedures due to lithotomy position used in them. Ifprolonged urological procedure is necessary patient should be monitored post operatively for early and prompt treatment of this complication. Early diagnosis and prompt treatment is the main-stay of the treatment in cases of acute compartment syndrome following unavoidable prolonged urological procedures in lithotomy position. We recommend a written consent and

Topic: Muscle and Compartmental Disorders
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
LHD LHDGAUSS_RAY_MWRM3 #162301.1 (analyzed)

Ray trajectories for microwave reflectometry (mwrm) at set3 point obtained using ray-tracing code LHDGauss.

Topic: Signaling Pathways in Disease
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Inhaled colistin in patients with non - cystic fibrosis bronchiectasis and chronic pseudomonas aeruginosa bronquial infection

<b>Introduction:</b> Treatment with inhaled colistin in chronic Pseudomonas aeruginosa bronchial infection in patients with non-cystic fibrosis bronchiectasis is gaining prominence. <b>Objectives:</b> To evaluate the relationship between the use of inhaled colistin and the eradication of Pseudomonas aeruginosa (PA), induction of resistance, exacerbations and lung function. <b>Methods:</b> Retrospective before-after study in patients with bronchiectasis and persistence of PA in sputum treated for at least one year with inhaled colistin from 2009-2015. The functional tests, sputum microbiology, number and type of exacerbations (hospital and non-hospital) were analyzed 1 year before and after the use of inhaled colistin. <b>Results:</b> The study included 49 patients with an average age of 72 years (SD± 10); 30 (61%) males. After 1 year of treatment with inhaled colistin: 55% PA sputum cultures were negative (p &lt;0.0001) and 45% positive PA and sensitive to colistin, while there was a decrease in non hospital exacerbations of 2 (SD ± 1.4) to 1 (SD ± 0.7 ) on average (p &lt;0.001) and of hospital exacerbations from 65% to 22.5% (p &lt;0.001). The walking test in patients with persistent positive cultures for PA decreased a mean of 42 mts (SD ± 77) (p=0.033). <b>Conclusions:</b> Inhaled colistin produces a significant eradication of PA in sputum cultures and a decrease in exacerbations. The long-term treatment with colistin did not induce resistance to PA. In spite of the treatment with inhaled colistin, patients with persistent positive cultures for PA showed a significant reduction in exercise capacity.

Topic: Cystic Fibrosis Research Advances
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Combining ability analysis of days to silking, plant height, yield components and kernel yield in maize breeding lines

The present study was carried out to determine the combining ability for yield and yield associated traits by crossing 8 diverse maize inbred lines in a half diallel mating design. Twenty eight F1 progenies along with their parents were planted in randomized complete block design with four replications in two environments. Combined analysis of variance showed significant mean squares of general combining ability (GCA) and specific combing ability (SCA) for days to ear silking (DS), plant height (PH), 1000-kernel weight (KW), number of kernels in ear row (KR), number of rows in ear (NR), kernel length (KL), cob to ear weight ratio (CR) and kernel yield (KY) indicating the importance of both additive and non additive genetic effects for these traits. However, high narrow-sense heritability estimates, low degree of dominance and the ratio of estimates of GCA to SCA effects for DS, KW, NR and CR indicated that additive genetic effect were more important for these traits. Most of the crosses with significant SCA effects for DS and KY had at least one parent with significant GCA effects for the same traits. Significant positive correlations were detected between KY and other yield components which included; KW, KR and KL. Therefore, these traits can be used as indirect selection criteria for seed yield improvement. The crosses MO17 × L8, MO17 × L12 and MO17 × L24 had high KY and were thus, considered as good combinations for improving the trait.

	 

	Key words: Additive, combined analysis, correlation, dominance, heritability.

Topic: Genetics and Plant Breeding
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Changes in intima media thickness, ankle brachial index and flow mediated dilation in pre hypertensive individuals

Introduction: Prehypertension (PH) is a state being on the frontier between the physiological referent arterial pressure values and pathological ones. The opinion concerned with its treatment is contradictory. Vascular alteration is an object of interest. Material and methods: Intima Media Thickness (IMT), Ankle Brachial Index (ABI) and Flow Mediated Dilation (FMD) indices were examined in 103 individuals with PH and 45 normotensives. Anthropometric and clinical chemical methods were also applied. The statistical processing was carried out by ÐœS Excel 2000 and SPSS 11.0. Results: The pre hypertensives` metabolic profile was unfavorable, they are overweight and have bigger waist size, reflecting in higher cardiovascular risk. The percentage of FMD is reduced as an expression of endothelial function. Structural vascular alterations are not registered - ITM and ABI values are of no significant difference in the two followed up groups. Conclusion: The therapeutic approach in prehypertensives should be directed to reestablishment of the endothelial function.

Topic: Cardiovascular Health and Disease Prevention
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Manihot esculenta COL2641

Plant Genetic Resource.<br>Taxonomy: Manihot esculenta<br>Common name(s): cassava<br>Other names: Hmc 2, Hmc 2<br>Conserved by: Centro Internacional de Agricultura Tropical (CIAT), Colombia<br>Local sample unique identifier: COL2641<br>Method of creation: Acquisition<br>Date: 1991-03-06<br>Other identifiers: n/a,CMC 260, n/a,CMC 260<br>Historical: No<br>Biological status: Breeding/research material<br>MLS status: Included

Topic: Antimicrobial Resistance in Staphylococcus
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
IMEMO in the First Part of the 2000s (HR and Organizational Issues)

The article is dedicated to the events in IMEMO in the first half of the 2000s, associated with the activities of the Academician Nodari Simoniya, the new director of the Institute. In 2002, Simoniya added Gennadii Chufrin to his team as one of his deputy directors. In 2002, the editor-in-chief of the “World Economy and International Relations” journal was replaced. After the death of German Diligenskii, who had been heading the journal since 1988, the well-known political scientist Andrei Ryabov became the new editor-in-chief. He managed to preserve the best traditions laid down by his predecessor. The article also traces the main measures for the partial reorganization of the Institute’s structure, carried out by the Academician Simoniya in 2001–2006. The author reveals the substance of this reorganization aimed at concentrating the efforts of the IMEMO research team on the study of the most pressing and important problems of the contemporary world. One of the important decisions was the creation of the Center for Energy Problems headed by the Director of the Institute. The emergence of this research unit was the result of numerous requests received by the Institute from government agencies and economic structures, which wanted to have qualified expert assessments in this area. Therefore, it was decided to concentrate research on energy problems in one Center. Several previously existing research subdivisions also underwent reorganization: the Department of Developing Countries, which studied the Third world, was transformed into the Center for Development and Modernization Problems, where, among other things, Russia’s problems were addressed; the Department studying the internal political processes in Western countries was transformed into the Center for Socio-Economic and Socio-Political Studies of Western Countries and Russia. The Department of North American Studies, the Department of International Political Problems, the Department of Global Economic Problems and Foreign Economic Policy, and the Center for Asia-Pacific Studies were reorganized as well in order to actualize their studies. The measures for the partial reorganization of IMEMO were explained not only by considerations of research expediency, but also by the increasingly insistent demands of the government to reduce the number of employees of academic institutes in the system of the Russian Academy of Sciences. By the end of 2006, there was a slight decrease in the number of doctors of sciences at the Institute in comparison with 2001. This was largely due to objective reasons – retirement or death of senior researchers. But at the same time, there was a significant influx of young people into the postgraduate school. In general, the management of IMEMO succeeded in preserving human resources and academic potential of the Institute.

Topic: Global Energy Security and Policy
Subfield: General Energy
Field: Energy
Domain: Physical Sciences
For Weber: Essays on the Sociology of Fate. By Bryan S. Turner. and The Rise of Western Rationalism: Max Weber's Developmental History. By Wolfgang Schluchter

For Weber: Essays on the Sociology of Fate.By Bryan S. Turner. and The Rise of Western Rationalism: Max Weber's Developmental History.By Wolfgang Schluchter Get access Dennis H. Wrong Dennis H. Wrong New York University Search for other works by this author on: Oxford Academic Google Scholar Social Forces, Volume 62, Issue 4, June 1984, Pages 1092–1094, https://doi.org/10.1093/sf/62.4.1092 Published: 01 June 1984

Topic: Weber, Simmel, Sociological Theory
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
PERSPECTIVE

identified by the international participants. The audiotapes from the workshop discussions were summarised by the organising chairs of the Symposium and the resulting document was circulated for input from all invited workshop participants. In total, 100 key questions and research needs were identified. Identified needs included: provision of different definitions depending on the use of data; explanations for differences in frequency studies; and better characterisation of genetic and environmental determinants of occupational asthma. The role of irritants and the pathogenesis of various forms of work-related asthma need further research, and there are also questions and research needs for diagnosis, prevention and understanding of persistence and airway remodelling. In conclusion, although advances have been made in the understanding of occupational asthma and other work-related asthma, further key issues remain that need addressing.

Topic: Botanical Studies and Applications
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Prokaryotic Community Structures in a Thermophilic Anaerobic Digestion Reactor Converting Poly( <scp>l</scp> -Lactic Acid) for a Long Period Revealed by 16S rRNA Gene Amplicon Sequencing

Little information on poly( l -lactic acid) (PLLA) treatment-associated microbiota in thermophilic anaerobic digestion reactors is available. Here, we provide 16S rRNA gene sequence data on microbiota in a thermophilic anaerobic digestion reactor converting PLLA to methane for 336 days. Data comprising 99,566 total high-quality reads were tabulated at the taxonomic class level.

Topic: Probiotics and Fermented Foods
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Cytokine induction after Epstein-Barr virus infection of peripheral T-lymphocytes in vitro

Abstract Background: Although the presence of Epstein-Barr virus (EBV) in different T-cell malignancies has been widely reported, there is very few data available for EBV infection of normal T cells. This leads to the lack of knowledge on the early events after T cell infection. Objective: Investigate the early events occurring after normal human peripheral T-cells are infected with EBV in vitro. Methods: T-cells were treated with EBV in vitro. The expression of tumor necrosis factor- α (TNF-α) mRNA were determined using reverse-transcription (RT)-PCR, and the level of TNF-α and interferon- γ (IFN-γ) in the culture supernatant were measured using ELISA. The effect of virus inactivation on cytokine induction from T-cells was also determined. Results: At the beginning of T cell infection by EBV, the expression of several lytic EBV transcripts (BALF5, BcLF1, and BLLF1) were observed using RT-PCR. This indicated the susceptibility of in vitro EBV infection and the entering lytic cycle of EBV-infected T-cells. The interactions of EBV with T-cells lead to induction of inflammatory cytokines, tumour necrosis factor- α (TNF-α) and interferon- γ (IFN-γ), production from the T-cells. Inactivation of the virus by UV irradiation eliminated the TNF-α and IFN-γ induction by EBV, suggesting the involvement in the expression of viral gene(s). Conclusion: This in vitro analysis demonstrated the cytokine induction by EBV after primary infection of T-cells.

Topic: Viral-associated cancers and disorders
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
The surgical treatment of idiopathic osteonecrosis of the femoral head.

The results of surgery in the treatment of osteonecrosis of the femoral head are analysed and discussed. Medullary decompression by the forage biopsy technique in the early stage facilitates normalisation of the intramedullary pressure and breaks the vicious circle constituted by ischaemia-oedema-increased medullary pressure-ischaemia which eventually produces bone death. Flexion osteotomy is indicated in the advanced stage (Ficat stage 3) provided certain parameters are respected such as the age of the patient, the stage of the lesion, the extent of the necrosis and the absence of secondary arthritis. For cases classified as Ficat stage 4, the only solution is total arthroprosthesis.

Topic: Bone and Joint Diseases
Subfield: Orthopedics and Sports Medicine
Field: Medicine
Domain: Health Sciences