jimnoneill/paper-to-field-training huggingface dataset:
Signal Feature Coverage and Testing for CPS Dataflow Models

Design of cyber-physical systems (CPS) typically involves dataflow modeling. The structure of dataflow models differs from the traditional software, making standard coverage metrics not appropriate for measuring the thoroughness of testing. To address this limitation, this article proposes signal feature coverage as a new coverage metric for systematically testing CPS dataflow models. We derive signal feature coverage by leveraging signal features. We developed a testing framework in Simulink, a popular dataflow modeling and simulation environment, that automates the generation and execution of test cases based on the defined coverage metric. We evaluated the effectiveness of our approach by carrying out experiments on five Simulink models tested against ten Signal Temporal Logic specifications. We compared our coverage-based testing approach to adaptive random testing, falsification testing, output diversity-based approaches, and testing using MathWorks’ Simulink Design Verifier. The results demonstrate that our coverage-based testing approach outperforms the conventional techniques regarding fault detection capability.

Topic: Software Testing and Debugging Techniques
Subfield: Software
Field: Computer Science
Domain: Physical Sciences
Physiological and biochemical responses of Hibiscus sabdariffa to drought stress in the presence of salicylic acid

Abstract Salicylic acid (SA) is one of the important signal molecules, which modulates plant responses to environmental stress. In the present work, impact of exogenous SA on some physiological and biochemical traits of Hibiscus sabdariffa in response to drought stress was studied. Hibiscus sabdariffa seedlings were exposed to six drought levels (0, -0.05, -0.1, -0.5, -0.75, and 1 MPa) with two SA concentrations (0 and 500 µM) in 5 days intervals up to 20 days in a factorial design. During drought stress period, the root and shoot growth, relative water content, pigments content, non-reducing sugar and starch content was significantly decreased. SA treatment cause prevention of the growth reduction and improvement of relative water content. Protein concentration was roughly unchanged during drought stress with SA, while, reducing sugars accumulates and non-reducing sugars and starch significantly decreases. The results show that exogenous SA application on leaves during drought stress can ameliorate detrimental effects of stress through reducing water loss and accumulating reducing sugars, which cause preserving turgor pressure of the cells.

Topic: Hibiscus Plant Research Studies
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
The study of ovulatory pattern following use of clomiphene citrate and anastrozole in infertile women with ovulatory dysfunction: A comparative study

Objective: To determine an efficacy of Anastrozole compared with clomiphene citrate to induce follicular growth and ovulation in infertile women with ovulatory dysfunction. Study Design: Comparative prospective study setting: The study was carried out in the department of Obstetrics and Gynaecology at AVBRH, Sawangi, Wardha. Patient(s): The study comprised a total of 100 infertile women (cycles) with ovulatory dysfunction. Intervention(s): Patient received anastrozole (1 mg /d;50 patient , 87 cycles) and CC (50 mg /d ;50 patient, 74 cycles) for 5 days , starting on day3 of mense. Result(s): In 1st treatment cycle the ovulation rates for anastrozole at 1 mg was 32% (n=50) ,compared with 54% (n=50) for Clomiphene citrate at 50 mg/d. in up to 3 cycles of treatment, cumulative ovulation rate was 59.4% with CC and 43.6% with anastrozole. Conclusion(s): CC 50 mg exerts a stronger stimulatory effect on follicular growth compared with 1 mg of anastrozole . Anastrozole was associated with significantly fewer mature and growing follicle and thicker endometrium.

Topic: Ovarian function and disorders
Subfield: Reproductive Medicine
Field: Medicine
Domain: Health Sciences
Time-Frequency Analysis of the Delta Modulation and PWM Control for the Asynchronous Motors

This work presents some considerations on a control method for a three-phase asynchronous motor and a time-frequency analysis of the proposed system. The control method uses the delta modulation principle to generate the command signals for a full bridge power inverter that drives three phase asynchronous motor. The time-frequency analysis can bring more new information that could be used to develop new control strategies. The operation principle and the analysis and simulation results are also presented to compare the performances of this control method versus a direct feed from mains

Topic: Gyrotron and Vacuum Electronics Research
Subfield: Atomic and Molecular Physics, and Optics
Field: Physics and Astronomy
Domain: Physical Sciences
Book Review: In the Bosom of the Father: The Collected Poems of Benedictine Mystic

Book Review of In the Bosom of the Father: The Collected Poems of Benedictine Mystic. Translated by Jacob Riyeff. Eugene, OR: Wipf and Stock, 2018, 226 pages

Topic: Early Modern Women Writers
Subfield: Religious studies
Field: Arts and Humanities
Domain: Social Sciences
The Prevalence of Renal Dysfunction in Young Adults with Sickle Cell Disease.

Abstract Sickle cell disease is typified by dramatic acute painful episodes, which consume the majority of patients’ and healthcare providers’ attention. However, the cumulative damage to vital organs that occurs in this disease is often the determinant of early death. The kidneys are a major target organ in sickle cell disease and renal failure is a highly morbid event. It is also strongly associated with early death. Glomerular hyperfiltration is often the earliest sign of renal injury. This is followed by return to apparently normal filtration rates, then successively lower rates, culminating in end-stage renal disease. Microalbuminuria follows hyperfiltration and progresses to frank proteinuria. We evaluated the prevalence of renal dysfunction in a cohort of patients with sickle cell disease managed at the University of Tennessee Cancer Institute’s adult sickle cell program. At entry into the program, patients underwent a routine battery of tests, including 24 hour urine collection for measurement of creatinine clearance and urine protein. Our findings are summarized in the table below. By the age of 25 years, almost 80% of patients with sickle cell disease showed significant abnormality of glomerular filtration and 40% had significant proteinuria. This worsens with age. By a median of 37 years, 2 in 3 patients have developed significant proteinuria and hypofiltration has become the predominant pattern of glomerular filtration abnormality. Since renal injury is reversible in the early stages, more emphasis needs to be placed on aggressive early screening, surveillance and intervention. Intervention at the stage of hyperfiltration and microalbuminuria is easier and much more likely to be successful. Patients and their healthcare providers need to be educated on the high prevalence of renal damage. Efforts at education, screening, surveillance and, where necessary, treatment should begin well before adolescence.

Topic: Hemoglobinopathies and Related Disorders
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
THE WOLFGANG MODEL: LESSONS FOR HOMICIDE RESEARCH IN THE 1990s

ABSTRACT There are a number of things that homicide research needs to do: (1) trace the volume of killing over time in various geo-political units; (2) delineate clearly the types of homicide that exist, for homicide is indeed a multidimensional, not unidimensional, phenomena; (3) specify the particular populations affected by these different types; and (4) determine the causes of each of these respective types as well as causes of increasing volume over time. Accomplishing these four objectives will allow us to reach the ultimate objective which is the development of social policies that can impact this lethal phenomena. This paper will analyze Marvin Wolfgang's classic work Patterns in Criminal Homicide to determine the contributions of his work to these overall objectives. It will do so by (1) briefly reviewing the major findings of Wolfgang's work on homicide; (2) reviewing studies of some other research scholars that have occurred since the publication of Wolfgang's work to show how homicide research has been advanced using his model; and (3) examining the advantages and limitations of the approach which he and others have used for understanding homicide and for the future of homicide research.

Topic: Crime Patterns and Interventions
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
The Implementation and Impact of a Revised National Childhood Immunization Schedule in an Urban Asian Community

Changes to the national childhood immunization schedule (NCIS) can have a potential impact on vaccine uptake in the community. The NCIS in Singapore has undergone several revisions over the years, with the most recent modification on 1 November 2020. The new NCIS includes, as routine, the influenza and the varicella vaccine, as well as two combination vaccines, the measles, mumps, rubella and varicella vaccine (MMRV), and the hexavalent diphtheria, acellular pertussis, tetanus, haemophilus influenza b, injectable polio, and hepatitis B vaccine (6-in-1). This retrospective database study aims to assess the effect of the new NCIS on (a) the vaccination uptake of children at 6 and 12 months and (b) the cost difference to the healthcare system and to parents. One-year vaccination data from two cohorts of children immunized according to the old (n = 10,916) and new NCIS (n = 10,299) were extracted, respectively, from their electronic medical records. The vaccine uptake at 6 and 12 months increased by 10.8 and 2.1%, respectively, with the new NCIS as compared to the old NCIS. The mean number of required visits to the primary care clinic for each child was reduced from six to four. There is an estimated 6.41% cost reduction with the new NCIS.

Topic: Vaccine Coverage and Hesitancy
Subfield: Health
Field: Social Sciences
Domain: Social Sciences
Meralgia Paresthetica After Spine Surgery on the Jackson Table

Meralgia paresthetica is a non–life-threatening neurological disorder characterized by numbness, tingling, and burning pain over the anterolateral thigh due to impingement of the lateral femoral cutaneous nerve. This disorder has been seen in patients with diabetes mellitus and obesity, but has also been observed in patients after procedures such as posterior spine surgery, iliac crest bone grafts, lumbar disk surgery, hernia repair, appendectomies, and pelvic osteotomies that ultimately lead to compression or damage to the lateral femoral cutaneous nerve. Overall, permanent sequelae of meralgia paresthetica are rare, however, some cases do require intervention.

Topic: Peripheral Nerve Disorders
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Prevalence and Risk Factors for Incontinence Among Emirati Women With Diabetes

Purpose: To estimate the prevalence and risk factors for urinary incontinence among a sample of Emirati women with diabetes. Design: A cross-sectional survey design using probability sampling was employed to evaluate incontinence among 350 Emirati diabetic women. Age, body mass index, history of urinary tract infections, parity, diabetes duration, and type of diabetes management were evaluated as potential risk factors for incontinence. To assess type and frequency of incontinence, items from the National Health and Nutrition Examination Survey–Kidney Condition–Urology were used. Findings: A total of 225 (64.3%) participants reported incontinence, with 110 (31.4%) expressed having an episode once a week or more. Both stress ( n = 197, 56.3%) and urge incontinence ( n = 208, 59.4%) were seen; 96 (48.7%) reported at least weekly stress incontinence episodes, and 109 (52.4%) reported weekly or more urge episodes. Results of logistic regression indicated that diabetes duration was the most significant risk factor for incontinence. Conclusion: Prevalence of incontinence in Emirati women was higher than that reported by diabetic women in other cultures. Practice Implications: Clinicians working with Emirati diabetic women should endeavor to enhance screening for incontinence and design culturally appropriate strategies for teaching and treating this complication of diabetes.

Topic: Pelvic floor disorders treatments
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Effect of Sprinkler Irrigation on Bacterial Soft Rot and Yield of Broccoli

The effect of amount of applied water under two irrigation frequencies (once versus three times per week) on the incidence of bacterial soft rot, caused by Erwinia carotovora subsp. carotovora, and yield of broccoli was investigated in field studies conducted in 1987 and 1988. At head initiation, the amount of applied water was varied by utilizing a line source irrigation system. Incidence of soft rot was higher in the OSU breeding line 86-3 plots, followed by cv. Citation and then cv. Gem. Soft rot was not consistently affected by amount of applied water. Differences in amount of disease were apparent, however, between the separate irrigation frequency studies in 1988; disease incidence more than doubled under the high- compared with the low-frequency irrigation. Further studies on the effects of frequency and timing of sprinkler irrigation on soft rot and yield of Gem broccoli were undertaken in 1993 and 1994. Six sprinkler irrigation regimes, a factorial combination of frequency (irrigation every 2, 4, or 8 days) and timing (morning or evening), were established. Total water applied did not differ by treatment. Incidence of soft rot was negligible at the first harvest in both years. At the last harvest, the incidence of soft rot was significantly reduced, from 22 to 10% in 1993 and from 30 to 15% in 1994, by the change in frequency of irrigation from 2 to 8 days. In contrast, timing of irrigation had no effect on disease incidence. Yield of broccoli was not affected by either frequency or timing of irrigation.

Topic: Plant Pathogenic Bacteria Studies
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Cars and sample probe measurementsin two pilot-scale natural gas flames

The design of a reliable low-NO x burner requires a good understanding of the mixing between the fuel and air jets. This is true both for technologies using staging of the combustion air and for those using exhaust gas recirculation. Therefore, there is a need for detailed measurements in the near-burner region to validate the theories on which the burner technology is based and to better understand the processes involved in this region of the furnace. This article presents intrusive measurements of conventional combustion products (O 2 , CO 2 , CO, and NO x ) and mean and fluctuating components of temperature using a laser-based measurement system (CARS) in two natural gas flames produced by two commercially available burners. Based on these measurements, the burners are compared with respect to combustion performance. The low-NO x burner produced similar amounts of NO x compared to the other burner. The reason for this is found in the differences in the fluctuating component of gas temperature in the flames from these burners. The low-NO x burner is shown to have broad temperature profiles resulting in much larger regions where the temperature is above the 1800 K limit for NO x formation compared to the high-NO x burner.

Topic: Combustion and flame dynamics
Subfield: Computational Mechanics
Field: Engineering
Domain: Physical Sciences
Rapid paper-based optical sensing of <i>Spilosoma obliqua nucleopolyhedrovirus via</i> ester hydrolysis

We have developed an easily scalable chromogenic probe for the dual-mode sensing of Spilosoma obliqua Nuclear polyhedrosis viruses (SpobNPV) in aqueous media.

Topic: Plant Virus Research Studies
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Mutation of Arginine 276 to Methionine Changes Mg2+ Cooperativity and the Kinetic Mechanism of Fructose-1,6-bisphosphatase

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMutation of Arginine 276 to Methionine Changes Mg2+ Cooperativity and the Kinetic Mechanism of Fructose-1,6-bisphosphataseRulin Zhang and Herbert J. FrommCite this: Biochemistry 1995, 34, 25, 8190–8195Publication Date (Print):January 27, 1995Publication History Published online1 May 2002Published inissue 27 January 1995https://pubs.acs.org/doi/10.1021/bi00025a026https://doi.org/10.1021/bi00025a026research-articleACS PublicationsRequest reuse permissionsArticle Views89Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Topic: Biochemical and Molecular Research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Paleoseismic studies of the San Francisco Peninsula segment of the San Andreas Fault zone near Woodside, California

A late Holocene slip rate is proposed for the San Francisco Peninsula segment of the San Andreas fault zone at the Filoli Center, located between the town of Woodside and Upper Crystal Springs Reservoir, California. At this site the primary trace of the San Andreas fault zone traverses N35°W across the head of a large alluvial fan, offsetting buried stream channel deposits. One deposit, with a minimum calibrated accelerator mass spectrometry (AMS) radiocarbon age of 2070±120 years B.P., is offset 30±2 m, yielding an average geologic slip rate of 17±4 mm yr −1 for the late Holocene. A stratigraphically lower channel sequence, with a minimum calibrated AMS radiocarbon age of 330±200 years B.P., is offset 4.1±0.5 m. We interpret that this older sequence records both the penultimate earthquake on the peninsula segment, accompanied by 1.6±0.7 m of dextral slip, and the ∼2.5 m of slip that occurred in 1906. On the basis of radiocarbon analyses and historical descriptions we propose that the pre‐1906 earthquake occurred in June 1838. Our interpretations suggest that the San Francisco Peninsula segment of the San Andreas fault zone may rupture in earthquakes of at least two magnitudes: (1) a large‐magnitude (≈ M w 8) event with a recurrence of ∼250–320 years that involves the North Coast, San Francisco Peninsula, and Santa Cruz Mountains segments, as occurred in 1906 and (2) a M w 7.0–7.4, 1838‐type event that ruptures only the San Francisco Peninsula segment. The apparent difference in slip rate of 7 ± 7 mm ‐yr −1 between the North Coast segment (24±3 mm yr −1 ) and the peninsula segment (17±4 mm yr −1 ) suggests a possible slip rate gradient on the northern California section of the San Andreas fault.

Topic: earthquake and tectonic studies
Subfield: Geophysics
Field: Earth and Planetary Sciences
Domain: Physical Sciences
Uncertainty about estimating total returns of Atlantic salmon, <i>Salmo salar</i> to the Gander River, Newfoundland, Canada, evaluated using a fish counting fence

Abstract For a number of rivers in Newfoundland, Atlantic salmon, Salmo salar L., is managed in relation to river‐specific conservation spawning requirements. One such river is the Gander River, where between 1989 and 1999, the escapement of Atlantic salmon, a major factor in assessing the status of stock, was determined using a fish counting fence. In 2000, the counting fence was discontinued and alternative means of calculating total returns were explored. Regression and simulation methods, using relationships between total returns and salmon counts at an upstream tributary during 1989–99, formed the basis for estimates of returns for 2000, and the uncertainty around estimates. The accuracy of methods is evaluated by retrospective comparisons with actual total returns between 1989 and 1999. Estimates of total returns deviated from the actual by as much as 50–60%, depending on the method. Management implications of the approach are discussed.

Topic: Fish Ecology and Management Studies
Subfield: Nature and Landscape Conservation
Field: Environmental Science
Domain: Physical Sciences
Optimization of Production-Distribution Network of Perishable High-Tech Products with Capacity

This paper address the problems of optimization of production -distribution network of the first and second generation products with capacity under uncertain environment in terms of perish ability and coexistence of high- tech products. The model examines the influential factors on demand of products such as response time, price, and substitution, then the demand id segmented. Response time model is established on the basis of stage features of the 2 generations products. The objective function of a non-linear integer programming model is formulated to determine the production scale, transportation mode and storage location. This research provides important reference for the manufacture to make decision.

Topic: Product Development and Customization
Subfield: Management of Technology and Innovation
Field: Business, Management and Accounting
Domain: Social Sciences
Dipyridamole-thallium imaging: the lazy man's stress test.

Dipyridamole-thallium imaging is a relatively safe and accurate method to evaluate myocardial perfusion and "stress." It is independent of patient motivation, exercise capacity and antianginal medications. Overall it detects coronary artery disease as well as exercise thallium and has already shown utility in prognostic determinations. The continued use of this test on a wide scale appears warranted and additional large scale experience needs to be critically evaluated.

Topic: Cardiac Imaging and Diagnostics
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Additional file 1 of Responsiveness and minimal clinically important difference of SGRQ-I and K-BILD in idiopathic pulmonary fibrosis

Additional file 1. Results of linear regression comparing SGRQ-I or K-BILD Total scores in groups of different stages of disease from baseline to 12 months. Patients were divided into three equally large groups according to stage of disease by SOBQ, SGRQ, FVC, DLCO and 6MWD. For GRCS, patients were divided into deteriorated, unchanged or improved.

Topic: Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences