jimnoneill/paper-to-field-training huggingface dataset:
Impact of Cultural Competency Training in Naturopathic Medical Students: Self-Assessed Changes in Awareness, Knowledge, Skills, and Attitudes

Introduction: Cultural competency training is a growing requirement in medical schools across North America. Although accredited naturopathic medical schools now include some elements of cultural competency training throughout their programs, no literature to date has evaluated the effect of cultural competency curriculum among naturopathic medical students. This study evaluated the impact of a cultural competency training program of 4th-year naturopathic medical students at an accredited naturopathic medical educational institution in North America. Methods: Pre- and post-training online surveys were completed by naturopathic medical students using a 1 to 5 numerical scale (least to most confident), self-evaluating their awareness, knowledge, skills, and willingness to change behaviours, with some survey items adapted from the short version of the Cross-Cultural Care Survey (Harvard). Descriptive statistics were calculated, and a paired two-sided Wilcoxon signed-rank test was used to examine changes between pre- and post-training responses. Results: Out of 134 students enrolled in the training, 46 participants completed both the pre- and post-training surveys and were included in the final analysis. There was a statistically significant increase in self-rated confidence from pre- to post-training across all individual survey items spanning improvements in cultural competency awareness, knowledge, skills, and attitudes among students who completed both surveys. Conclusions: Results from this study indicate that cultural competency training of naturopathic students may improve their subjective assessment of their awareness, knowledge, skills, and attitudes related to working with diversity in clinical practice. Future research would benefit from using validated assessment scales, reducing loss to follow up, and investigating factors such as social demographics, prior training, and lived experience amongst participants.

Topic: Cultural Competency in Health Care
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Comparative Study on the Effect of Recesses on Conical Hybrid Journal Bearing Compensated with CFV under Micropolar Fluid Lubrication

This paper theoretically presents the comparative performances of conical hybrid journal bearing with 4-pockets and 6-pockets compensated with constant flow valve (CFV) under micropolar fluid lubrication for various semi-cone angles. The numerical solution of the modified Reynolds equation for micropolar fluid flow on the conical surface has been done by using finite element method using Galerkin’s technique along with the necessary boundary conditions and iterative scheme. The bearing performances have been presented for two different semi-cone angles, radial load and the restrictor design parameter. It is observed that bearing performances improve for 6-pockets CFV than 4-pockets. The bearing performances also increase with increase in semi-cone angle, constant flow valve restrictor and micropolar parameters significantly. With increase in semi-cone angle of bearing the direct stiffness, damping coefficients and the stability have been observed to increase under micropolar lubrication for 6-pockets CFV restrictors.

Topic: Tribology and Lubrication Engineering
Subfield: Mechanical Engineering
Field: Engineering
Domain: Physical Sciences
A Comparative Study of Interactional Meta-discourse in English Speeches of Chinese and American Stateswomen

By comparing Hillary and Fu Ying’s political speeches from the perspective of interactional meta-discourse, this paper is aimed at exploring the similarities and differences of Chinese and American stateswomen’s employment of interactional meta-discourse in their political speeches, and discussing the possible causes of such similarities and distinctions. This study suggests that interactional meta-discourse are frequently used in English speeches of both Chinese and American stateswomen, but American stateswomen utilize much more interactional meta-discourse than their Chinese counterparts. As for the five sub-categories, engagement marker and self-mention occur the most repeatedly, whereas booster the least frequently in both corpora. However, Chinese stateswomen use more hedges but less attitude marker, self-mention and engagement marker than American stateswomen. The reasons for such similarities may be the necessity of interacting with the audience in a political speech, while the causes of distinctions may be the different cultural backgrounds and expression styles of China and America.

Topic: Discourse Analysis in Language Studies
Subfield: Literature and Literary Theory
Field: Arts and Humanities
Domain: Social Sciences
A search for bcl1, bcl2, and c-myc oncogene rearrangements in chronic lymphocytic leukemia.

Three cellular or putative oncogenes: c-myc, bcl1, and bcl2 were previously found to be rearranged in some B cell malignancies due to chromosomal translocations. Data concerning the role of such genetic rearrangements in B-CLL are very scanty and limited to few cases in which bcl1 rearrangements were found. We studied DNA samples from 38 cases of B-CLL by Southern blot technique in order to find out the existence and frequency of such events. No bcl1 or bcl2 rearrangements were found in any of the studied cases; thus, involvement of these genes in CLL must be rare. In one patient who had an aggressive and resistant disease, c-myc rearrangement was found.

Topic: Chronic Lymphocytic Leukemia Research
Subfield: Genetics
Field: Medicine
Domain: Health Sciences
Influence of Multi Extrusion Die Process on Mechanical and Chemical Behavior of 2024-T3 Alloy

In this paper, a cold multi-pass extrusion process for a &lt;i&gt;15mm&lt;/i&gt; in diameter solid 2024-T3 aluminum alloy rod was carried out using three dies to obtain three different diameters of &lt;i&gt;14mm, 13mm&lt;/i&gt;, and &lt;i&gt;12mm&lt;/i&gt;. The microstructure, hardness, and corrosion behavior were investigated before and after the extrusion process. Load-Displacement data were recorded during each extrusion process. The electrochemical corrosion test was made in a &lt;i&gt;3.5 wt.&lt;/i&gt;% NaCl solution using potentiostat instrument under static potentials test. Corrosion current was recorded to determine the corrosion rate for specimens. The results showed that the extrusion load increased with the number of extrusion passes, which is also seen in hardness test results. In addition, the corrosion rate decreased with the increase in the number of extrusion passes. This is due to severe plastic deformation, which generates a fine grain structure of (AlCu) and (AlCuMg) components.

Topic: Aluminum Alloy Microstructure Properties
Subfield: Aerospace Engineering
Field: Engineering
Domain: Physical Sciences
Mitochondrial-encoded MOTS-c prevents pancreatic islet destruction in autoimmune diabetes

(Cell Reports 36, 109447-1–109447-16.e1–e7; July 27, 2021) In the originally published version of this article, Tables S2B and S2C contained typo errors, affecting insulin and units of some parameters, and clinical information errors. The corrected table now appears with the paper online. This correction does not change results in the text. The authors regret these errors. Mitochondrial-encoded MOTS-c prevents pancreatic islet destruction in autoimmune diabetesKong et al.Cell ReportsJuly 27, 2021In BriefKong et al. report that a mitochondrial-encoded peptide, MOTS-c, prevents autoimmune diabetes when treated in NOD mice by modulating CD4+ T cell function, including metabolism and preferred differentiation into Treg cells. T1D patients have lower circulating MOTS-c levels, which correlate with the metabolic state of their CD4+ T cells. Full-Text PDF Open Access

Topic: GDF15 and Related Biomarkers
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
The rate of action of atropine.

The rate of action of atropine has been studied in isolated guinea-pig atria, perfused hearts (Langendorff) and longitudinal muscle strips from the guinea-pig ileum. Evidence for a relatively rapid atropine-receptor reaction was obtained by direct observation of hearts perfused at high perfusion pressures, and also from the action of fast-acting antagonists in the presence of atropine in atria and ileum, and from the acceleration of the effect of atropine by pretreatment with dibenamine. In view of this evidence, it appears that the rate of action of atropine in isolated atrium and ileum (or longitudinal muscle strips) is limited by the rate of access of atropine to the receptor region, and not by the rate of the atropine-receptor reaction. The evidence in the literature appearing to support the opposite view is discussed, and it is argued that an access-limited model may be found to explain all the facts. In particular, the affinity of a drug for the muscarinic receptor will be the factor governing its rate of action. The precise roles of such factors as pacemaker shifts, special diffusion barriers and various drug-binding sites other than receptors have not yet been worked out.

Topic: Receptor Mechanisms and Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Effect of compositional variation of dental MTA cements on setting time

치과용 MTA (Mineral Trioxide Aggregate) 시멘트의 긴 경화시간은 임상사용에서 큰 단점이다. 본 연구는 시판되는 9종 MTA제품의 경화시간을 ISO 6876:2012 표준방법에 따라 5회 반복 측정하였다. 평가된 재료는 ProRoot MTA (PR), Ortho MTA (Ortho), Retro MTA (Retro), Endocem MTA (Endocem), Endoseal MTA (Endoseal), One-Fil (OF), MTA Cem (MC), EZ-Seal (EZ), 및 Biodentine (BD) 이었다. 경화시간에 미치는 조성의 영향을 평가하기 위하여 XRD 및 XRF 분석을 시행하였다. 경화시간 결과값 사이의 유의성은 비모수 검정 방법인 Kruskal-Wallis 분석 후 Duncan 사후검정을 통해 다중분석하였다. 경화시간은 PR > EZ > OF > Ortho > Retro > MC > Endoseal > BD > Endocem 순 이었다 (p < 0.001). PR은 가장 긴(369.4 분), Endocem은 가장 짧은(2.4 분) 경화시간을 보였다. Endocem (2.4 분), BD (16.0 분) 및 Endoseal (47.0 분)은 탄산칼슘(calcium carbonate)를 함유하였고, 그 다음으로 경화시간이 짧았던 MC (48.8 분), Retro (43.6 분), Ortho (65.0 분) 및 OF (165.4 분)는 알루민산 이석회(dicalcium aluminate)를 함유하였다. EZ (182.4 분)는 초기강도 형성에 기여하는 규산 삼석회(tricalcium silicate)보다는 규산 이석회(dicalcium silicate)가 주 결정상을 이뤘고, 황산칼슘(calcium sulfate)을 함유하였다. 가장 짧은 경화시간을 보인 Endocem은 가장 작은 d90 입도(6.12 μm)를 보였다. 본 연구결과는 MTA 시멘트의 경화시간 조절을 위한 조성 개발과 각 임상 증례에 적합한 경화시간을 갖는 제품의 선택에 도움이 될 것으로 사료된다.

Topic: Endodontics and Root Canal Treatments
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
A Characterization of the Linear P−O−P Bonds in M<sup>4+</sup>(P<sub>2</sub>O<sub>7</sub>) Compounds:  Bond-Angle Determination by Solid-State NMR

Many compounds of the type M4+(P2O7) contain, in their room-temperature structure, both linear and bent pyrophosphate groups. The commonly found packing motif is usually described as a 3 × 3 × 3 cubic superstructure (Pa3̄ with Z = 108) where 11% of the P−O−P angles are predicted by diffraction methods to be in the unusual linear configuration. Using a novel variant of two-dimensional (2D) exchange NMR spectroscopy, we have measured, in a the cubic room-temperature structure of SiP2O7, the angle between the 31P chemical-shift-anisotropy (CSA) tensors in covalently bonded P−O−P unit. The selectivity to covalently bonded pairs is achieved by using the scalar coupling interaction as the driving force for polarization exchange during the mixing time of a two-dimensional exchange experiment. The NMR data show that the "linear" pyrophosphate groups in SiP2O7 are in fact linear on the NMR time scale (∼100 μs). A static disorder of "normal" bent units, postulated previously, is clearly excluded.

Topic: Advanced NMR Techniques and Applications
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Effects of Treatment with Nilvadipine on Cerebral Ischemia in Rats.

The protective effects of a Ca2+ antagonist, nilvadipine, on focal cerebral ischemia were studied in male spontaneously hypertensive rats. The animals received either nilvadipine (3mg x kg(-1) x day(-1)) or a vehicle subcutaneously. Group 1 (n=11) was treated for 7 days, and Group 2 (n=11) for 14 days. The middle cerebral artery was occluded on the 6th (Group 1) or 13th (Group 2) day of the treatment, and neuropathological outcomes were quantified 24 hours later. The mean arterial blood pressure was significantly reduced with nilvadipine to normal levels. The % infarct volumes of Groups 1 (37+/-2) and 2 (34+/-3) were significantly less than those of their controls (39+/-3 [n=11] and 40+/-4 [n=12], respectively), although the difference between Groups 1 and 2 was not significant. When infarct areas were compared in each of 8 coronal sections, the infarct size had decreased in the 5 posterior sections in Group 2, but only in 2 sections of Group 1. A significant decrease in the edema volumes was observed in Group 2, but not in Group 1. Thus, nilvadipine provided protective effects against cerebral ischemia in rats having chronic hypertension, and the effects were dependent on the duration of treatment.

Topic: Neonatal and fetal brain pathology
Subfield: Pediatrics, Perinatology and Child Health
Field: Medicine
Domain: Health Sciences
The use of pronase-digested human leukocytes to improve specificity of the flow cytometric crossmatch

Abstract Two-color fluorescence cytometry (FCXM) has recently been introduced to improve the detection of anti-HLA antibodies that react to donor cells, especially in recipients receiving kidney allografts. Although this assay system is highly sensitive, it lacks specificity. Between 70% and 90% of potential kidney recipients with a positive FCXM would have been denied transplant if such an assay had been used alone to detect antidonor antibodies. Lack of specificity is principally due to normal or irrelevant IgG in aggregates or immune complexes binding to Fcy R receptors on lymphocytes including B cells and a significant subset of T cells. To circumvent this problem, we digested Fcy R receptors on lymphocytes with pronase. We present data demonstrating that pronase digestion of lymphocytes does not alter HLA antigenicity. In addition, pronased lymphocytes allow one to use either single- or two-color FCXM. With single-color FCXM, one can quantitate antibody reactivity to lymphocytes via a cursor (on the fluorescence histogram) that separates lymphocytes that do not bind to antibodies. We present data demonstrating that this modification renders FCXM highly sensitive and specific. In addition, one can discriminate between IgG and IgM antibodies that react to lymphocytes.

Topic: Renal Transplantation Outcomes and Treatments
Subfield: Transplantation
Field: Medicine
Domain: Health Sciences
Transport preferences of the students and employers in Lublin University of Technology

The problem of movement is very important in the context of logistic management, which has been gaining importance in recent years with the increasing phenomenon of people moving to large urban agglomerations. The article presents the transport preferences of employees and students the Lublin University of Technology. IT tools were used for the analysis, such as the Analysis ToolPak add-on and PowerMap in Microsoft Excel.

Topic: transportation and logistics systems
Subfield: Transportation
Field: Social Sciences
Domain: Social Sciences
Judicial Administration and Enforcement of the Right to Quality Education in South Africa: A Discussion of Selected Case Laws

This paper examines the judicial intervention in safeguarding the comprehension and the fulfilment of the right to quality education through its pronouncements and judgements. The paper showcase that these judgements and pronouncements have now become essential regulatory tools shaping the administration and enforcement of the right to quality education in South Africa. It emphasizes that the judiciary on its pronouncements showcase the importance of understanding the meaning of the right to education and steadfast the significance of having social services connected to the learning environment for the delivery and realization of quality and sustainable education. It concludes that this right is inalienable and as such, it is incumbent on the government and institutions responsible for the protection of this right to certify that the right is promoted, protected and provided for at all cost. The paper recommends that the judiciary must continuously contribute in ensuring that quality education is promoted and protected by pronouncing judgements that promote quality sustainable education connected with good social services in schools across South Africa.&#x0D; &#x0D; Received: 20 August 2021 / Accepted: 15 December 2021 / Published: 5 March 2022

Topic: Human Rights and Development
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Philosophical Foundations of Various Approaches to Medical Ethical Decision Making

Journal Article Philosophical Foundations of Various Approaches to Medical Ethical Decision Making Get access Donnie J. Self Donnie J. Self Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Medicine and Philosophy: A Forum for Bioethics and Philosophy of Medicine, Volume 4, Issue 1, March 1979, Pages 20–31, https://doi.org/10.1093/jmp/4.1.20 Published: 01 March 1979

Topic: Ethics in medical practice
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
A guide to the solo songs of Johannes Brahms

Preface Brahms as Song Composer Six Gesange for Tenor or Soprano Six Gesange for Soprano or Tenor Six Gesange Lieder and Romanzen Five Gedichte Lieder and Gesange to Texts by Platen and Daumer Romanzen from Tieck's aeMageloneAe Fopur Gesange Four Gesange Five Lieder Seven Lieder Five Lieder Lieder and Gesange to Texts by G. F. Daumer Eight Lieder and Gesange Eight Lieder and Gesange Nine Lieder and Gesange Nine Gesange Four Gesange Five Gesange Five Gesange Five Romanzen and Lieder for One or Two Voices Six Lieder Six Lieder for Low Voice Two Gesange for Alto Voice with Viola Five Lieder for Low Voice Seven Lieder Four Lieder Six Lieder Eight Zigeunerlieder for Solo Voice Five Lieder for Low Voice Five Lieder Five Lieder Four Ernste Gesange Mondnacht, Wo0 21 Regenlied, Wo0 posth. 23 Poets and Translators Settings of Folksong Texts Selected Bibliography Index of Titles and First Lines

Topic: Musicology and Musical Analysis
Subfield: Music
Field: Arts and Humanities
Domain: Social Sciences
Indwelling pleural catheters vs. pleurodesis for malignant pleural effusions: a meta-analysis

<b>Introduction:</b> The choice between pleurodesis and indwelling pleural catheters (IPC) for the management of malignant pleural effusions (MPE) has been a significant controversial topic because not one of the two interventions has conclusively shown to be clinically superior to each other. <b>Methods:</b> We performed a meta-analysis of randomized controlled trials that compared pleurodesis versus IPC in terms of control of effusion, length of hospital stay, quality of life, chest pain and complication rates. <b>Results:</b> Four randomized trials (n=472) were analyzed. IPC showed a significantly decreased hospital LOS (reduction by 3.63 days (4.15-3.16days). There is also a trend toward less loculations (45%), reintervention (40%) and increased survival in the IPC group. Meanwhile, pleurodesis showed a trend toward better QOL, less empyema and chest pain. <b>Conclusion:</b> Compared to pleurodesis, IPC significantly decreased the length of hospital stay and showed a trend toward less recurrence and improved survival. Pleurodesis had a trend towards favorable results in terms of quality of life, complication rates, empyema and chest pain.

Topic: Pleural and Pulmonary Diseases
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
G1 phase cell cycle arrest in NSCLC in response to LZ-106, an analog of enoxacin, is orchestrated through ROS overproduction in a P53-dependent manner

LZ-106, a newly synthetized analog of quinolone, has been shown to be highly effective in non-small cell lung cancer (NSCLC) in both cultured cells and xenograft mouse model with low toxicity, yet the molecular mechanisms still require exploration. Here, we substantiated the involvement of P53 activation in intracellular reactive oxygen species (ROS) generation upon LZ-106 treatment and related P53 to the ROS-induced viability inhibition and apoptosis, which was exhibited in the previous research. P53 was shown to play an indispensable role in the elevated levels of intracellular ROS in LZ-106-treated NSCLC cells through ROS detection. We further identified the anti-proliferation effect of LZ-106 in NSCLC cells through G1 phase cell cycle arrest by cell cycle analysis, with the expression analysis of the key proteins, and discovered that the cell cycle arrest effect is also mediated by induction of ROS in a P53-dependent manner. In addition, the tumor suppression effect exhibited in vivo was demonstrated to be similar to that in vitro, which requires the participation of P53. Thus, LZ-106 is a potent antitumor drug possessing potent proliferation inhibition and apoptosis induction ability through the P53-dependent ROS modulation both in vitro and in vivo.

Topic: Cancer therapeutics and mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Principals in Title I Schools with Teachers Integrating the New Literacies of Online Reading and Research

This article examines the instructional leadership characteristics of a principal in a Title I school with classroom teachers integrating new literacies. The two dominant frameworks guiding this study were: instructional leadership and the dual-level theory of New Literacies. This qualitative, case study design included one principal and three teachers in a Title I elementary school Northeast Kansas. The principal in this study created a culture of trust and professional growth through the following actions: goals and expectations were individualized; teachers felt safe to experiment and take risks; resources, encouragement and support occurred; opportunities for ongoing, differentiated professional development were implemented; and opportunities to collaborate.

Topic: Literacy, Media, and Education
Subfield: Literature and Literary Theory
Field: Arts and Humanities
Domain: Social Sciences
Subcellular Localization of the S Locus F-box Protein AhSLF-S2 in Pollen and Pollen Tubes of Self-Incompatible Antirrhinum

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Topic: Plant Reproductive Biology
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences