jimnoneill/paper-to-field-training huggingface dataset:
Mitogenic and receptor activities of human growth hormone 108-129.

We have selectively synthesized a number of peptides encompassing the region of helix 3 of growth hormone (GH). These peptides and native human (h) GH have been evaluated for mitogenic and receptor activities in 3T3-F442A preadipocytes. In this system, wild type hGH is anti-mitogenic. In contrast, hGH 108-129 stimulated DNA synthesis while other GH-derived peptides were ineffective. hGH (L) 108-129 had an EC50 of about 0.2 nM and was maximally effective at about 0.5 nM in stimulating [3H]thymidine incorporation in 3T3-F442A cells. hGH (L) 108-129 was mitogenically as active as insulin-like growth factor-I and more active than insulin. It was less effective than transforming growth factor-beta. By cell cycle analysis, hGH (L) 108-129 increased the proportion of cells in S/G2/M phases to 28%. hGH, when coincubated with hGH (L) 108-129, blocked the mitogenic response of the peptide. A monoclonal antibody to the GH receptor significantly reduced binding of 125I-hGH to its receptor but had no effect on binding of 125I-hGH (L) 108-129. Affinity cross-linking of 125I-hGH to its receptor was not duplicated with 125I-hGH (L) 108-129. No other GH peptides or insulin competed for binding of 125I-hGH 108-129. Scatchard analysis indicated a Kd of 5.2 nM with 5.6 x 10(5) binding sites/cell for hGH (L) 108-129. These studies indicate that hGH (L) 108-129, a sequence encompassing helix 3 of hGH, acts by binding to a site other than the GH receptor and evokes high mitogenic responses.

Topic: Growth Hormone and Insulin-like Growth Factors
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Gingival Diseases in Children and Adolescents

Gingival diseases are prevalent in both children and adolescents. These diseases may or may not be associatedwith plaques, maybe familial in some cases, or may coexist with systemic illness. However, gingiva andperiodontium receive scant attention as the primary dentition does not last for a considerable duration. Asgingival diseases result in the marked breakdown of periodontal tissue, and premature tooth loss affectingthe nutrition and global development of a child/adolescent, precise identification and management ofgingival diseases is of paramount importance. This article comprehensively discusses the nature, spectrum,and management of gingival diseases.

Topic: Oral and gingival health research
Subfield: Pharmacy
Field: Health Professions
Domain: Health Sciences
Some Rearrangement Reactions of Organosodium and Organolithium Compounds

In continuation of rearrangement reactions of organometallic compounds, it was desirable to ascertain whether R-Metal combinations (free of halogen or other acidic groups) would react after the manner of benzylmagnesium chloride types with compounds like formaldehyde, for example. This last reaction gives not only the normal product (beta-phenylethyl alcohol), but also o-tolyl carbinol. It has been shown that the corresponding organosodium and organolithium compounds behave in a similar manner. Incidentally, it is possible to prepare some organolithium compounds, like phenyl-lithium, very conveniently, in a short time, and in excellent yields in the customary three-necked flasks.

Topic: Coordination Chemistry and Organometallics
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
CCDC 624678: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Topic: Crystallization and Solubility Studies
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Speedtest Open Data - Australia 2020 Q2, Q3 extract

This is an Australian extract of Speedtest Open data available at Amazon WS (link below - opendata.aws).<br>AWS data licence is "CC BY-NC-SA 4.0", so use of this data must be:- non-commercial (NC)- reuse must be share-alike (SA)(add same licence).This restricts the standard CC-BY Figshare licence.<br>A world speedtest open data was dowloaded (&gt;400Mb, 7M lines of data). An extract of Australia's location (lat, long) revealed 88,000 lines of data (attached as csv).<br>A Jupyter notebook of extract process is attached.A link to Twitter thread of outputs provided.A link to Data tutorial provided (GitHub), including Jupyter Notebook to analyse World Speedtest data, selecting one US State.<br>Data Shows: (Q2)- 3.1M speedtests- 762,000 devices- 88,000 grid locations (600m * 600m), summarised as a point- average speed 33.7Mbps (down), 12.4M (up)- Max speed 724Mbps- data is for 600m * 600m grids, showing average speed up/down, number of tests, and number of users (IP). Added centroid, and now lat/long.<br>See tweet of image of centroids also attached.<br>Versions:v7 - Rename to include Q2, Q3 in Title.v6 - Add Q3 20 data. Rename geojson AUS data as Q2. Add comparative Histogram. Calc in International.ipynb.v5 - add Jupyter Notebook inc Histograms. Hist is count of geo-locations avg download speed (unweighted by tests).v4 - added Melb choropleth (png 50Mpix) inc legend. (To do - add Melb.geojson)v3 - Add super fast data (&gt;100Mbps) less than 1% of data - 697 lines. Includes png of superfast.plot(). Link below to Google Maps version of superfast data points. Also Google map of first 100 data points - sample data. Geojson format for loading into GeoPandas, per Jupyter Notebook. New version of Jupyter Notebook, v.1.1.v2 - add centroids image.v1 - initial data load.

Topic: Traffic Prediction and Management Techniques
Subfield: Building and Construction
Field: Engineering
Domain: Physical Sciences
Dowsing for Potential Temporary Autonomous Zones: A Psychotopology of the Alternative Lifestyles of Nomadic Artisans in Mexico

By using qualitative data gathered from semi-structured interviews and participant observation, this study performs a psychotopological investigation of the lifestyles of nomadic artisans in Mexico in order to determine if the spaces created through the performance of such lifestyles are conducive to the germination of Temporary Autonomous Zones (Bey, 1990). In so doing, it analyzes these artisans' understandings and performances of time, space and mobility and the ways in which they lend themselves to free demonstrations of creative activity. It also examines whether or not such free expressions of creative activity, which are a fundamental part of these alternative lifestyles, are coupled with demonstrations of psychic nomadism and a rejection of psychic imperialism. Overall, the findings suggest that the lifestyles of these artisans may be conducive to the germination of a TAZ. However, such an occurrence is largely dependent on the artisans' subjective intentions and the achievement of unity among them.

Topic: Culinary Culture and Tourism
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Turn-on angle control for switched reluctance wind power generator system

The developed switched reluctance variable speed generator system was introduced. The component parts of the system and the turn-on angle control strategy were presented. The fuzzy logic algorithm for constant output power control was described. The variation of the phase winding DC output voltage and the variation of the phase winding DC output current were the two input control parameters. The turn-on angle of the main switches was the output control parameter. The experimental tested results of the prototype were given.

Topic: Electric Motor Design and Analysis
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Sonorism and the Polish Avant-Garde 1958-1966

This thesis was digitised for the purposes of Document Delivery. It is not available on open access and access is restricted. The item may be requested on Interlibrary Loan or viewed in the Rare Book Library at the University of Sydney. If you are the author of this work and would like it to be made available on open access please contact the Sydney eScholarship Repository Coordinator - escholarship.info@sydney.edu.au

Topic: Musicology and Musical Analysis
Subfield: Music
Field: Arts and Humanities
Domain: Social Sciences
Efficacy of artesunate and praziquantel combination on the prevalence of urinary schistosomiasis among children in Abua/Odual Local Government Area, Rivers State, Nigeria

A study to evaluate the efficacy of artesunate and praziquantel on urinary schistosomiasis was conducted in children between ages of 5-19 years in some communities in Abua/Odual Local Government Area of Rivers State, Nigeria. A total of three hundred and two (302) individuals who gave consent were assessed for the disease using the concentration technique. 55 (18.21%) infected individuals were exposed to the drugs in various regimens; Artessunate (4mg/kg x 3 times daily = 12mg/kg); Praziquantel (single oral dose of 40mg/kg) and Artesunate + Praziquantel combination (single oral dose of 40mg/kg + 4mg/kg x 3 times daily = 12mg/kg). A 40 (74.43%) reduction in the geometric egg count (eggs/ 1ml of urine) was recorded in the study with Artesunate single oral dose recording 11(64.70) cure, Praziquantel; 15(88.24) and the Artesunate + Praziquantel Combination; 14 (82.35). The three drug regimens variably reduced the clinical symptoms; heamaturia and proteinuria in the infected children. Sex and age of the children did not influence efficaciousness of the drugs. Praziquantel was more efficacious followed by the Artesunate + Praziquantel regimen. Arsunate single dose can substitute effectively for the chemotherapy of urinary schistosomiasis in endemic malarious regions of Nigeria. The study had revealed Artesunate as a cost effective intervention in the control of urinary schistosomiasis in the sampled areas of Abua/ Odua LGA of Rivers State.Keywords: Urinary schistosomiasis; Artesunate; Praziquantel; haematuria; proteinuria; geometric mean egg count

Topic: Parasites and Host Interactions
Subfield: Parasitology
Field: Immunology and Microbiology
Domain: Life Sciences
Porosity enhancement of biochar derived from rubber sawdust using steam injection at low temperature

Biochar is extremely interesting for energy and environment applications such assoil amender, sorbent materials and biofuels. In this study, rubber sawdust (RS) was prepared through the pyrolysis at 400 and 600°C with low and high heating rate (7 and 20°C/min) for 60 minutes.The pyrolytic parameters have a strong influence on biochar properties. Biochar yield was decreased from 33.1 to 22.6 wt% due to increasing of pyrolytic temperature. The higest BET surface area of biochar previous enhanced porosity was found about 410 m2/g at 600°C with 20°C/min of heating rate with particle size 0.3-1 mm. Afterwards, biochar porosity was enhanced through the steam injection process. Furthermore, the physicochemical properties of biochar product (i.e. surface morphology, BET surface area, and N2adsorption isotherm) will be characterized. (Texte intégral)

Topic: Thermochemical Biomass Conversion Processes
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Rubberlike Products from Linear Polyesters

Abstract The polymers which result from the condensation of dibasic acids with propylene glycol are viscous gums which can be vulcanized to rubberlike products. In the unpigmented condition these rubbers are quite weak, but when reinforced with suitable pigments their strength and elongation compare favorably with other synthetic rubbers. Because polyesters of known structure and molecular weight can be easily synthesized, these polymers are useful for the study of the relations between structure and properties in rubberlike materials in general. Factors affecting tensile strength, oil resistance, brittle temperature, and stability are discussed. The development of rubberlike products from linear polyesters was announced in a short news article more than three years ago, but a detailed description of their preparation and physical properties has not been published. The object of this paper is to review these properties. However, the paper is written not so much from the viewpoint of offering a synthetic rubber for practical use as from that of applying linear polyesters to the study of the relations between structure and properties of rubberlike substances in general. As has been pointed out in other articles, the linear polyesters are well suited to serve as models in such a study, since molecules of definitely known constitution and molecular-weight distribution can be synthesized by relatively simple methods. Furthermore, the chemical structure of the polyester chain molecules can be varied in a definite and controlled manner by the choice of suitable glycol and dibasic acid or hydroxy acid reactants. The structure of the chains in the case of the former, assuming equal molar proportions, may be represented by the general formula:

Topic: Polymer Nanocomposites and Properties
Subfield: Polymers and Plastics
Field: Materials Science
Domain: Physical Sciences
Cytological Aspects of Cervico-Uterine Smears from HIV/HPV HR Coinfected Women Treated with Antiretrovirals

Introduction: Women living with HIV are at high risk of developing persistent HPV-HR infections. This favors the development of precancerous lesions that may progress to cervical cancer. With a view to improving management and taking preventive action against cervical lesions and cervical cancer in women living with HIV, our study aimed to describe cervical abnormalities and establish a relationship between lesion severity and HPV-HR genotypes in HIV/HPV-HR co-infected women. Methodology: This was a descriptive cross-sectional study conducted at the CTAB from March 2021-December 2022. Of 122 women living with HIV screened HPV HR positive 90 presented for FCU. Cervico-uterine smears were read after Papanicolaou staining by two cytopathologists at the anatomy-cytology-pathology laboratory of the university hospital center. Results were rendered according to the 2014 Bethesda system classification, and data processing was performed using SPSS 25 software. Results: 90 patients co-infected with HIV/HPV-HR were included, with a mean age of 44.16±10.08 years, ranging from 20 to 70 years. The women in our study were all on triple therapy, and most had a controlled viral load and CD4 count above 200mm3. Cytological abnormalities accounted for 38.9%, with a predominance of atypical squamous cells of undetermined significance (ASCUS) 51.43%, followed by low-grade squamous intraepithelial lesions (LSIL) 37.14% and 11.43% of atypical squamous cells for which a high-grade lesion could not be excluded (ASC-H). Triple therapy had a protective impact in women against progression to precancerous states, although no statistically significant association was observed between cervical lesions and HR-HPV genotypes (p=0.819). Conclusion: Our study reveals a high proportion of ASCUS lesions in women living with HIV and co-infected with HPV HR. Triple therapy has a protective effect against progression to severe lesions. To this end, screening for precancerous lesions in this population should include diagnosis of the P16 protein by Histoimmuno chemistry. Key words: FCU, HR- HPV, Women, HIV, ARV, Congo.

Topic: Cervical Cancer and HPV Research
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Numerical analysis of heat pumps models: comparative study between equation-fit and refrigerant cycle based models

An equation-fit (EF) and a refrigerant cycle (RC) based heat pump models have been implemented, validated, analyzed and compared to each other under steady state conditions for a brine to water heat
pump. Models validations have been provided through comparisons against experimental data obtained at ISFH. The advantages and disadvantages of the both models have been identified. This work provides significant inputs regarding the selection of a specific model depending on the needs. Analysis of mass flow rates and calculations far from typical catalogue data (non-standard conditions) are provided. The
main conclusions can be summarized as: i) the EF model is recommended when the boundary conditions for the estimation and prediction modes are the same and when non-standard conditions are considered;
ii) the RC model is the chosen alternative when the mass flow rates are modified from the estimation to the prediction mode.

Topic: Refrigeration and Air Conditioning Technologies
Subfield: Mechanical Engineering
Field: Engineering
Domain: Physical Sciences
MicroRNA expression profiling during upland cotton gland forming age by microarray and quantitative reverse-transcription polymerase chain reaction (qRT-PCR)

Plant microRNAs (miRNAs) have important impacts on growth, development, flowering, metabolism and response to stress.Studies indicate that post-transcriptional processes are important for regulating gene expression during development.However, we still have very limited knowledge on the regulatory mechanisms associated with this process.In particular, the function of miRNAs during gland morphogenesis in cotton remains unknown.In this study, we used the Affymetrix GeneChip miRNA Array (v11.0-therSpecies) and quantitative reverse transcriptase-PCR (qRT-PCR) to identify additional microRNAs during gland morphogenesis of near-isogenic lines in upland cotton.The results showed that 30 miRNAs were differentially expressed: 24 up-regulated (miR156, miR157, miR166 and miR390 families) and six down-regulated (miR149, miR169, miR289, miR705, miR1224 and miR1227 families).Some microRNAs, such as ghb-miR169a_st and ghr-miR166b_st, were confirmed by qRT-PCR assays.There was no significant difference in miRNA levels between the microarray and qRT-PCR.Analysis of the transcript data for some miRNA target genes indicated that they play an important role in the pathogenesis and development of gland morphogenesis.In summary, our results showed that some known miRNAs were expressed in the gland of upland cotton, and most of them were of low abundance.This data may be useful in future studies associated with gland control involved in the terpenoid aldehyde biosynthesis pathway, genetic engineering and molecular breeding of cotton.

Topic: Plant Molecular Biology Research
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Volumetric pulp chambers measurements in mandibular and maxillary permanent first molar using cone-beam computed tomography by age and gender

Aim: The aim of this study was to demonstrate the anatomical structure of pulp chamber, measure the volume of the total pulp chambers in mm3 and evaluate the pulp chamber volume changes by age and gender statistically in mandibular and maxillary first molars by means of CBCT.&#x0D; Methodology: In our study, CBCT examinations of patients between the ages of 7-18 years, which were carried out due to different reasons were evaluated retrospectively. The CBCT images of healthy total of 160 lower and upper right permanent first molar teeth were selected randomly and the volumes of the total pulp chamber were measured in mm3 with the 3D Slicer software program. We analyzed the collected data with statistical analysis methods and we evaluated whether there was any difference between the patients grouped according to the age in respect of volume changes in the total pulp chamber and whether there was any difference between the mean volume values and gender of the patients within the same group.&#x0D; Results: Comparison of the volume measurements of the lower and upper first permanent molar teeth between the groups showed that the volume values of the total pulp chamber decreased depending on the age (p&lt;0.05). Regarding gender, volume decrease related to age was statistically more significant among females. We determined in all age groups except age 7-9 group that the volume value of the total pulp chamber of the upper permanent first molar teeth was statistically higher than the volume value of the total pulp chamber of the lower permanent first molar teeth (p&lt;0,05).&#x0D; Conclusion: We believe that CBCT is an easy and conservative method for the 3D-imaging of the pulp chamber, volume measurement and examination of the dimensional changes of the total pulp chamber depending on deposition of secondary dentin.&#x0D; &#x0D; How to cite this article: Açıklar Kavas A, Tümen EC. Volumetric pulp chambers measurements in mandibular and maxillary permanent first molar using cone-beam computed tomography by age and gender. Int Dent Res 2019;9(1):30-40.&#x0D; &#x0D; Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

Topic: Endodontics and Root Canal Treatments
Subfield: Oral Surgery
Field: Dentistry
Domain: Health Sciences
Efficiency and Linearity Enhancement of Microwave GaN Power Amplifiers Using Harmonic Injection

This thesis addresses an architecture for enhancing efficiency and linearity of GaN power amplifiers using external second harmonic injection at the output. This transmitter architecture has potential uses in communication and radar systems which have stringent requirements of low DC power dissipation and minimum out of band interference. An idealized theoretical analysis based on expansions of the nonlinear transfer function of a PA predicts the measured improvements in linearity and efficiency.\nThe experimental demostration is performed with both hybrid and integrated harmonically-injected PA using discrete GaN 6W transistors in class-AB mode with 55% PAE at a fundamental frequency of 2.45 GHz. Harmonic injection at the output is shown to enhance the efficiency of the PA to 89%. For a slightly reduced efficiency of 78%, the linearity can be improved and &gt; 15 dB reduction of third and fifth order intermodulation distortion tones is measured in compression.\nIntegration of a dynamic supply of the harmonically-injected PA is also investigated in order to achieve high efficiency and linearity for signals with Peak-to-Average ratios (PARs) of 6 dB and higher. Experimental results demonstrate a 70-80% efficient HI-PA for an output power variation of 6 dB. Reduction in third order nonlinear products and AM-PM distortion shows improved linearity of the PA over the entire range of power levels.\nFinally, the concept is extended to an X-band GaN MMIC to demonstrate integration and efficiency enhancement at 10 GHz with a 4 W, 47% efficient class-AB PA, with an expected final efficiency of over 60% with harmonic injection.

Topic: Advanced Power Amplifier Design
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences