THE CHRONIC TYPHOID CARRIER. III. THERAPY WITH ANTAGONISTIC BACILLUS, ANTIBIOTICS AND SULFONAMIDES

Article1 August 1950THE CHRONIC TYPHOID CARRIER. III. THERAPY WITH ANTAGONISTIC BACILLUS, ANTIBIOTICS AND SULFONAMIDESJ. A. VAICHULIS, Ph.D., A. LITTMAN, M.D., A. C. IVY, Ph.D., M.D., F.A.C.P., G. ZUBOWICZ, M.D., R. KAPLAN, M.D.J. A. VAICHULIS, Ph.D.Search for more papers by this author, A. LITTMAN, M.D.Search for more papers by this author, A. C. IVY, Ph.D., M.D., F.A.C.P.Search for more papers by this author, G. ZUBOWICZ, M.D.Search for more papers by this author, R. KAPLAN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-33-2-361 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONThe treatment of chronic typhoid carriers is an important public health problem. Hundreds of non-surgical methods of therapy have been tried and found ineffective.While cholecystectomy results in the cure of 70 per cent or more of biliary carriers, there are patients who refuse or who are too ill for this operation. There are also many extra-cholecystic carriers. Although the morbidity and mortality incident to cholecystectomy are low in many surgical clinics, it is undesirable to remove the gall bladder because of an infection which may not have destroyed the functional ability of that organ.It is the purpose...Bibliography1. LittmanVaichulisIvyKaplanBaer AJAACRWH: The chronic typhoid carrier: I. The natural course of the carrier state, Am. J. Pub. Health 38: 1675, 1948. CrossrefGoogle Scholar2. Nissle : Ueber die Grundlagen einer neuen ursachlichen Bekampfung der pathologischen Darmflora, Deutsch. med. Wchnschr. 42: 1181, 1916. CrossrefGoogle Scholar3. Bigger JW: Synergistic action of penicillin and sulphathiazole on B. typhosum , Lancet 1: 81, 1946. CrossrefMedlineGoogle Scholar4. ComerfordRichmondKay CHAWW: Typhoid carriers treated with penicillin and sulfathiazole, Lancet 2: 343, 1946. CrossrefMedlineGoogle Scholar5. KornsTrussell RFRE: Treatment of the typhoid carrier state, J. Lab. and Clin. Med. 33: 1150, 1948. MedlineGoogle Scholar6. BiggerDaly JWRW: The treatment of typhoid carriers with penicillin and sulphathiazole, Lancet 1: 296, 1949. CrossrefMedlineGoogle Scholar7. Hardy AV: Bacteriostatic action of sulfadiazine on E. typhosa in carriers and cases, Pub. Health Rep. 58: 833, 1943. CrossrefGoogle Scholar8. CollerCrabtree FAP: Chronic biliary typhoid carriers, Surgery 12: 426, 1942. Google Scholar9. Vaichulis JA: Unpublished data. Google Scholar10. Sievers JJ: Weekly report, Division of Communicable Disease, Illinois Department of Public Health, Feb. 12, 1949. Google Scholar11. LittmanVaichulisIvy AJAAC: The chronic typhoid carrier: II. The effect of cholecystectomy on the bacteriologic course, J. Lab. and Clin. Med. 34: 549, 1949. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Rock Island, Illinois*Received for publication August 12, 1949.From the Manteno State Hospital, Manteno, Illinois, State of Illinois Department of Public Welfare, and the Department of Clinical Science, University of Illinois, Chicago, Illinois.The coöperation of Dr. Alfred Paul Bay, Superintendent, Dr. D. A. Manelli, Assistant Superintendent and Dr. Otto Lohman, Public Health Officer of the Manteno State Hospital is gratefully acknowledged.The cultures of "antagonistic bacilli" used for therapy were prepared by Dr. P. S. Carley and Mr. L. Shermerdiak. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byMicro-cells beneath organic lacquers: a study using scanning Kelvin probe and scanning acoustic microscopyDie SalmonellosenTrinkwasserchlorination, Darmflora und Infektionskrankheiten, insbesondere TuberkuloseAntibacterial Agents in Gastrointestinal DiseaseUntersuchungen über die Wirkung des Jodtetragnost auf Bakterien der T.P.E.-GruppeGeneral abstracts 1 August 1950Volume 33, Issue 2Page: 361-370KeywordsAntibioticsBacillusBladderCholecystectomyMorbidityMortalityPrevention, policy, and public healthSulfonamideTyphoid ePublished: 1 December 2008 Issue Published: 1 August 1950 PDF downloadLoading ...

Topic: Cancer Research and Treatments
Subfield: Biotechnology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences