jimnoneill/paper-to-field-training huggingface dataset:
Rapid Platform Exploration – A Sprint to Discover and Design Digital Platform Business Models

In recent years, the significance of digital platform business models has been increasing. This growth creates an increasing demand for tools that companies and startups can apply to find and develop sustainable platform business models. Today, various platform design tools are available to help companies and startups in the platform development. Previous research by Brecht et al. (2021) on the validation of platform business models has provided methods requiring, amongst others, a discovered and verified business model. However, there is a lack of research in establishing guidelines on how to reach this verified state. By applying the Google Sprint, a popular method to quickly generate insights into a variety of problems and enriching it with platform design tools, this research creates the Smart Platform Design Sprint (SPDS). The SPDS provides a solution to discover and obtain a verified business model. Its novelty lies in incurring the speed of the Google Sprint and incorporating the expertise of platform design tools. Through a series of expert interviews, the SPDS is improved, and its necessity verified. In future research, the SPDS awaits application in a practical setting showing its feasibility. Keywords: platform design tools, business model, exploration, google sprint, smart platform experiment cycle

Topic: Digital Platforms and Economics
Subfield: Strategy and Management
Field: Business, Management and Accounting
Domain: Social Sciences
Hydrogen Sulfide Hydrate Dissociation in the Presence of Liquid Water

Of the major components found in lean sour natural gas (CH4, H2S, CO2, H2O), hydrogen sulfide (H2S) readily forms the one of the highest temperature hydrates in the presence of water (structure I). Thus, when heating wellheads, flowlines, processing and injection facilities, the H2S hydrate formation conditions dictate the design for flow assurance purposes. Due to the high toxicity of H2S, there is a paucity of hydrate formation/dissociation condition data in the literature, especially in the liquid H2S region. In fact, there are only four previous experimental decomposition measurements reported in the literature for liquid H2S. In this work, we report the dissociation of pure H2S hydrate in the presence of water for p = 0.360 to 16.343 MPa and T = 285.23 to 304.04 K. These measurements were carried out in a 25 cm3 stirred autoclave cell, where both the Lw–H–H2S(g) and Lw–H–H2S(l) phase boundaries were autonomously measured by using the phase boundary dissociation method. These new measurements augment our previously reported data, which were below the vapor pressure of H2S. The results obtained were used to fit a semiempirical Clausius–Clapeyron equation for the rapid calculation of H2S hydrate formation conditions. Also, the results were thermodynamically modeled using the reference quality reduced Helmholtz energy equations of state and the van der Waals and Platteeuw model for fluid and hydrate phases, respectively. Finally, the results obtained from the model were compared to available literature where the uncertainty in temperature was found to be within an average ±0.2 K.

Topic: Methane Hydrates and Related Phenomena
Subfield: Environmental Chemistry
Field: Environmental Science
Domain: Physical Sciences
Cytotoxic, Antioxidant and Apoptotic Effects of Twenty Sri Lankan Endemic Plants in Breast Cancer Cells

Aims: Main aim of this study was to evaluate cytotoxic, antioxidant and apoptotic properties of Sri Lankan endemic plants in estrogen receptor positive (MCF-7) breast cancer and triple negative breast cancer (MDA-MB-231) cells.Place and Duration of Study: At the Institute of Biochemistry, Molecular Biology and Biotechnology, between June 2013 and May 2015.Methodology: We investigated leaf and bark extracts (hexane, chloroform, ethyl acetate, methanol) of twenty endemic plants for possible cytotoxicity against breast cancer (on estrogen receptor positive MCF-7 and triple negative MDA-MB-231 breast cancer) cell lines and normal Original Research Article mammary epithelial cells (MCF-10A).Cytotoxic extracts were also investigated for possible apoptotic effects on MDA-MB-231 cells by caspase 3/7 estimation.Total polyphenols, flavonoids and the free radical scavenging activity of the extracts were also measured.Results: Of the 156 solvent extracts from 20 plants studied only 35 extracts from 14 plants were significantly cytotoxic [18 extracts to MCF-7 cells (IC 50 31.43to 97.50 µg/mL), 7 extracts to MDA-MB-231 cells (IC 50 16.11 to 95.83 µg/mL) and 10 extracts (IC 50 0.51 to 99.35 µg/mL) to both cell lines] with only some of these being less cytotoxic to normal breast epithelial cells.Caspase 3/7 was activated by some of the cytotoxic extracts.Polyphenol and free radical scavenging activity were high in most of the methanol and ethyl acetate extracts.Flavonoids were present in all the extracts in varying quantities. Conclusion:The cytotoxic and apoptotic potential demonstrated by some plants endemic to Sri Lanka, indicates strong leads for future drug discovery for combating breast cancer.

Topic: Phytochemicals and Antioxidant Activities
Subfield: Biochemistry
Field: Medicine
Domain: Health Sciences
Addition of anti-leukotriene agents to inhaled corticosteroids for chronic asthma

The addition of licensed doses of anti-leukotrienes to add-on therapy to inhaled glucocorticoids brings modest improvement in lung function. Although addition of anti-leukotrienes to inhaled glucocorticoids appears comparable to increasing the dose of inhaled steroids, the power of the review is insufficient to confirm the equivalence of both treatment options. Addition of anti-leukotrienes is associated with superior asthma control after glucocorticoid tapering; although the glucocorticoid-sparing effect cannot be quantified at present, it appears modest.

Topic: Asthma and respiratory diseases
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Antioxidant Activity, Total Phenolic and Flavonoid Content of Berberis aristata DC. and Berberis thomsoniana C.K. Schneid. from Sagarmatha National Park, Nepal

Background: Medicinal plants are the major sources of the crude drugs and natural antioxidants. Berberis species have been used in the treatment of various ailments around the world including Nepal. However, systematic study on phytochemistry and pharmacology of Berberis species from Nepal is lacking. Objectives: To evaluate the antioxidant activity, total phenolic and flavonoid contents of Berberis aristata and Berberis thomsoniana from Sagarmatha National Park. Materials and Methods: Antioxidant activity was measured through 2, 2-Diphenyl-1-Picrylhydrazyl assay. Total phenolic and flavonoid content were estimated using Folin–Ciocalteau and aluminum chloride method respectively. Results: Samples showed dose-dependent radical scavenging activity. Radical scavenging activity of the methanolic extracts of different parts of B. aristata and B. thomsoniana ranged from 19.38 to 98.47%, with leaf extracts of B. thomsoniana showing the strongest activity. The total phenolic content of the samples varied from 11.04 to 65.30 mg GAE g-1 dry weight whereas total flavonoid content was in between 2.4 to 16.46 mg quercetin/g dry weight. Conclusion: Among the tested samples, leaf extracts of B. thomsoniana showed the strongest antioxidant activity and contained the highest amount of total phenolic and flavonoid content.

Topic: Ethnobotanical and Medicinal Plants Studies
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
A Mathematical Model Simulating Organic Variation in Bioreactor Landfill

Leachate can be disposed in situ and solid wastes stabilization accelerated in bioreactor landfills.In order to investigate organic dynamic variation and influencing factors in bioreactor landfills,a mathematical model simulating organic variation in the leachate of bioreactor landfill was presented and demonstrated based on mass balance of contaminants and degradation kinetics.The model was solved numerically using a fourth-order Runge-Kutta algorithm and the model parameters were validated by monitoring data in simulated experiment.The simulating results are close to monitoring data,which indicates that biodegraded organic concentration has been forecasted accurately by this model.Given the limitations in data capture,a sensitivity analysis is performed,highlighting the model's response to changes in input variables.The results show that leaching velocity constant from solid to liquid and degradation velocity constant of organic in liquid have significant effect on simulating outcome.

Topic: Landfill Environmental Impact Studies
Subfield: Industrial and Manufacturing Engineering
Field: Environmental Science
Domain: Physical Sciences
Supplementary Figure 4 from Inhibition of miR-17 and miR-20a by Oridonin Triggers Apoptosis and Reverses Chemoresistance by Derepressing BIM-S

&lt;p&gt;PDF file - 32KB, Effects of miRNA inhibitors of the miR-17-19b cluster on the expression of BIM-S.&lt;/p&gt;

Topic: Bioactive Natural Diterpenoids Research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Are the Most Effective Approaches towards Helping Students with Emotional Behavioural Disorders (EBDs) Predisposed and Trait Based?

Trait emotional intelligence (EI) may prove to be most valuable as an approach for dealing with others’ behaviours/emotions via its related psychological processes. Personality trait theory posits that an individual’s level of EI affects their cognitive-affective-behavioural reaction towards students with emotional behavioural disorders (EBDs) and influences the level of difficult behaviour. EI would be an essential element in fostering supportive interactions with students as a way of preventing and/or managing disruptive behaviours. The author explores which individuals are more predisposed to discriminate against EBD students using an attribution model framework and identifies the most effective and supportive EI traits. Two hundred and sixty-one teachers from 51 Victorian schools completed self-report questionnaires, including the Trait Emotional Intelligence Questionnaire. A quantitative survey methodology used vignettes (depicting a student with either mild or severe EBD symptoms), with 50/50 surveys randomly distributed. Teacher EI predicted the behaviour towards students with EBDs, whilst bypassing or biasing conscious thought processing. Combinations of EI traits were identified that produced the most desirable outcomes, demonstrating EI’s propensity to direct reactions towards a more effective or dysfunctional helping approach. The findings suggest that the most effective approaches towards helping EBD students are the innate dispositional reactions that establish the necessary psychological foundations for any successful interaction or outcome. The development of an assessment tool (Assessment Screen for Emotionally Intelligent Teachers (ASET)) lays a sound foundation for profiling teachers with these ideal qualities.

Topic: Emotional Intelligence and Performance
Subfield: Social Psychology
Field: Psychology
Domain: Social Sciences
JUSTINIAN AND HIS IMPACT - (F.K.) Haarer Justinian. Empire and Society in the Sixth Century. Pp. xxii + 274, ills, maps. Edinburgh: Edinburgh University Press, 2022. Paper, £29.99 (Cased, £95). ISBN: 978-0-7486-3678-5 (978-0-7486-3677-8 hbk).

JUSTINIAN AND HIS IMPACT - (F.K.) Haarer Justinian. Empire and Society in the Sixth Century. Pp. xxii + 274, ills, maps. Edinburgh: Edinburgh University Press, 2022. Paper, £29.99 (Cased, £95). ISBN: 978-0-7486-3678-5 (978-0-7486-3677-8 hbk). - Volume 73 Issue 1

Topic: Classical Antiquity Studies
Subfield: Anthropology
Field: Social Sciences
Domain: Social Sciences
Division or Union of Labor? Analyzing Workers’ Representation in the Argentine Congress

Abstract Does social background affect legislators’ behavior in office? Do individuals with specific social ties tend to be mainly concerned with representing their group of reference, beyond partisanship? This article deals with these questions by analyzing bill-drafting patterns by representatives in the Argentine Congress who belong to an understudied group: workers. The wide presence of a broad, populist party (Peronism) that historically incorporated organized labor, along with other groups, provides consistent variation for empirical assessment. Evidence demonstrates that only labor-based representatives in general, regardless of party membership, tend to use legislative resources to target workers, while every other member of the populist party does not consider labor issues at all in their legislative tasks. Such findings open new directions for analysis of representation, legislative performance, and strategies developed by dissimilar groups in broad political organizations.

Topic: Politics and Society in Latin America
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
Wiener Index, Hyper-wiener Index, Harary Index and Hamiltonicity of graphs

In this paper, we discuss the Hamiltonicity of graphs in terms of Wiener index, hyper-Wiener index and Harary index of their quasi-complement or complement. Firstly, we give some sufficient conditions for an balanced bipartite graph with given the minimum degree to be traceable and Hamiltonian, respectively. Secondly, we present some sufficient conditions for a nearly balanced bipartite graph with given the minimum degree to be traceable. Thirdly, we establish some conditions for a graph with given the minimum degree to be traceable and Hamiltonian, respectively. Finally, we provide some conditions for a $k$-connected graph to be Hamilton-connected and traceable for every vertex, respectively.

Topic: Graph theory and applications
Subfield: Geometry and Topology
Field: Mathematics
Domain: Physical Sciences
WA 0822-1455-5757 Distributor Jual Herbalife di Tanggung Gunung Tulungagung

Hubungi WA 0822-1455-5757 Alamat, Distributor Jual Herbalife di Pondok Aren Banten\n\nAlamat Agen Distributor Jual Herbalife di Pondok Aren Banten, Distributor Jual Herbalife di Semarang Utara, Distributor Jual Herbalife di Tembalang, Distributor Jual Herbalife di Jebres, Distributor Jual Herbalife di Laweyan, Distributor Jual Herbalife di Pasar Kliwon, Distributor Jual Herbalife di Serengan, Distributor Jual Herbalife di Margadana\n\nKelas Diet Online Program Slim Marathon 10 Hari Herbalife.\n\nCall HP WA 0822-1455-5757\nKami adalah distributor Resmi Herbalife produsen makanan kesehatan\nKelas Diet Online\nAgen Herbalife\nHerbalife Terdekat\nNo Telepon Kelas Diet Online\n\n\n#DistributorHerbalifediPondokArenBanten, #DistributorHerbalifediSemarangUtara, #DistributorHerbalifediTembalang, #DistributorHerbalifediJebres, #DistributorHerbalifediLaweyan, #DistributorHerbalifediPasarKliwon, #DistributorHerbalifediSerengan, #DistributorHerbalifediMargadana\n\n

Topic: Hermeneutics and Narrative Identity
Subfield: Philosophy
Field: Arts and Humanities
Domain: Social Sciences
The conundrum of articulating societal knowledge and technology demand

One of the strategies to 'make knowledge work' is to design ways to enhance the articulation of knowledge demands in society, assuming that such articulation will lead to the production (or co-creation) of more relevant knowledge and technology. Using five mini case studies, this chapter critically examines the idea that demand-articulation can enhance the applicability of knowledge generated in a straightforward manner. Assumptions that are critically examined include: (a) the idea that prospective users and scientists have a similar idea about what 'research' entails and what kinds of questions may be answered by it; (b) the idea that citizens can explicate unequivocally what it is that they need; (c) the idea that answers and solutions that result from citizen's questions will face less constraints in terms of their applicability; (d) the idea that it is the research results rather than the research process that has impact in society; and finally (e) the idea that articulating the demands of citizens is sufficient to escape from the linear model of innovation. Identification of the limitations in these assumptions helps to understand why the results of involving citizens in agenda setting for research are often disappointing. Finally, I discuss implications for the practice of involving citizens in knowledge creation and provision, and propose an altogether different view of how demand-articulation may be embedded in society.

Topic: Innovative Approaches in Technology and Social Development
Subfield: Management of Technology and Innovation
Field: Business, Management and Accounting
Domain: Social Sciences
Treatment of cervical stenotic myelopathy: a cost and outcome comparison of laminoplasty versus laminectomy and lateral mass fusion

Object Cervical stenotic myelopathy due to spondylosis or ossification of the posterior longitudinal ligament is often treated with laminoplasty or cervical laminectomy (with fusion). The goal of this study was to compare outcomes, radiographic results, complications, and implant costs associated with these 2 treatments. Methods The authors analyzed the records of 56 patients (age range 42–81 years) who were surgically treated for cervical stenosis. Of this group, 30 underwent laminoplasty and 26 underwent laminectomy with fusion. Patients who had cervical kyphosis or spondylolisthesis were excluded. An average of 4 levels were instrumented in the laminoplasty group and 5 levels in the fusion group (p &lt; 0.01). Forty-two percent of the fusions crossed the cervicothoracic junction, but no laminoplasty instrumentation crossed the cervicothoracic junction, and it only reached C-7 in one-third of the cases. Preoperative and postoperative Nurick grades and modified Japanese Orthopaedic Association (mJOA) scores were obtained. Outcomes were also assessed with neck pain visual analog scale (VAS) scores and the Odom outcome criteria. Postoperative length of stay, complications, and implant costs were calculated. Results The mean duration of follow-up, average patient age, and length of hospital stay were similar for both groups. The mean Nurick scores were also similar in the 2 groups and improved an average of 1.4 points in both (p &lt; 0.01 for preoperative-postoperative comparison in each group). The mean mJOA scores improved 2.7 points in laminoplasty patients and 2.8 points in fusion patients (p &lt; 0.01 for each group). The mean VAS scores for neck pain did not change significantly in the laminoplasty cohort (3.2 ± 2.8 [SD] preoperatively vs 3.4 ± 2.6 postoperatively, p = 0.50). In the fusion cohort, the mean VAS scores improved from 5.8 ± 3.2 to 3.0 ± 2.3 (p &lt; 0.01). Excellent or good Odom outcomes were observed in 76.7% of the patients in the laminoplasty cohort and 80.8% of those in the fusion cohort (p = 0.71). In the fusion group, complications were twice as common and implant costs were nearly 3 times as high as in the laminoplasty group. When cases involving fusions crossing the cervicothoracic junction were excluded, analysis showed similar complication rates in the 2 groups. Conclusions Patients treated with laminoplasty and patients treated with laminectomy and fusion had similar improvements in Nurick scores, mJOA scores, and Odom outcomes. Patients who underwent fusion typically had higher preoperative neck pain scores, but their neck pain improved significantly after surgery. There was no significant change in the neck pain scores of patients treated with laminoplasty. Our series suggests cervical fusion significantly reduces neck pain in patients with stenotic myelopathy, but that the cost of the implant and rate of reoperation are greater than in laminoplasty.

Topic: Cervical and Thoracic Myelopathy
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Homogenization of water and sediment bacterial communities in a shallow lake (Lake Balihe, China)

All samples were from Lake Balihe which is a subtropical fish farming lake in China. Water and sediment samples from all 18 locations were collected in four seasons (autumn, November 2018; winter, January 2019; spring, April 2019 and summer, July 2019). <br> Total genomic DNA was extracted using the SDS method. PCR amplified the V3-V4 region of the 16S rRNA gene using the general bacteria primers 341F (5’-CCTAYGGGRBGCASCAG-3’) and 806R (5’-GGACTACNNGGGTATCTAAT-3’) with appropriate sample-specific barcodes. Single-end (400 bp) sequencing was performed on the Ion S5TM XL platform.<br>

Topic: Microbial Community Ecology and Physiology
Subfield: Ecology
Field: Environmental Science
Domain: Physical Sciences
The Relationship Between Remote Work and Job Satisfaction: The Mediating Roles of Perceived Autonomy, Work-Family Conflict, and Telecommuting Intensity

The purpose of the current study was to examine the relationship between remote work and job satisfaction levels of employees in the workplace. Additionally, the variables perceived autonomy, work-family conflict, and telecommuting intensity were investigated as mediators. A total of 185 employees participated in the study, which utilized an online survey. Results showed that remote work had a positive relationship with job satisfaction. Perceived autonomy, work-family conflict, and telecommuting intensity each mediated the relationship between remote work and job satisfaction. An inverted u-shaped curvilinear relationship between the extent of working remotely (telecommuting intensity) and job satisfaction was not found and instead support for a positive, linear relationship was found. The major implication of the findings is that increasing remote work in the workplace may be an efficient way to increase employees’ job satisfaction levels. This is because remote work influences employees to have higher perceived autonomy, less work-family conflict, and more telecommuting intensity, which in turn influences their job satisfaction.

Topic: Work-Family Balance Challenges
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
LHD AXUVD #22075.1

20-channel Absolute eXtreme Ultra-Violet (AXUV) detector (photodiode) arrays installed inside the vacuum vessel of LHD to monitor MHD fluctuations of AXUV emissions from edge plasma region

Topic: Beetle Biology and Toxicology Studies
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences