jimnoneill/paper-to-field-training huggingface dataset:
Design and development prototype of measurement oxygen saturation in blood (SpO2) as early detection happy hypoxia in Covid-19 patients

The Covid-19 pandemic outbreak is still not over. Even today, there are many cases of people without symptoms (OTG=Orang Tanpa Gejala/People Without Symptoms). The sufferer does not feel the symptoms of fever, cough and runny nose. Patients can still do activities as usual, but suddenly experience shortness of breath and decreased consciousness due to lack of oxygen. This phenomenon of reducing the amount of oxygen in the body without causing symptoms is known as happy hypoxia. This study aims to design a prototype measurement of blood oxygen saturation (SpO2) as an early detection of happy hypoxia in Covid-19 patients using a pulse oximeter sensor and non-invasive methods (without surgery). The sensor is placed on the patient's fingertip and will measure the intensity of light that penetrates the bloodstream at the fingertip. The measurement data is compared with an oximeter and this tool has the highest error of 0.02% and the lowest 0.01%.

Topic: Non-Invasive Vital Sign Monitoring
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Dormancy induction by summer temperatures and/or desiccation in imbibed seeds of trumpet daffodils <i>Narcissus alcaracensis</i> and <i>N. longispathus</i> (Amaryllidaceae)

Abstract We analysed the effects of summer temperatures (28/14 °C) and/or desiccation (from 48% to 8% humidity) on imbibed Narcissus alcaracensis and N. longispathus seeds with an elongating embryo. In the N. alcaracensis seeds that overcame dormancy (embryo elongation = 27.14%), exposure to high temperatures induced secondary dormancy and reduced subsequent embryo growth. A further 3‐month cold stratification (5 °C) was required to break secondary dormancy. Desiccation in early embryo growth stages (elongation = 11.42%) also reduced germination. Desiccation in the seeds in a more advanced growth stage ( i.e . embryo elongation = 27.14%) induced secondary dormancy, which the further 3‐month cold stratification did not overcome. When desiccation was preceded by high temperatures, seeds better overcame secondary dormancy ( i.e . longer embryo elongation and seed germination). Treatments did not affect seed viability. In the N. longispathus seeds that overcame dormancy (embryo elongation = 59.21%), exposure to high temperatures induced secondary dormancy and they needed a further 1‐month stratification at 15/4 °C + 2 months at 5 °C to reactivate the germination process. When embryo elongation was 42.10%, seed desiccation totally impeded subsequent germination. When embryo elongation reached 59.21%, desiccation induced secondary dormancy, which was not overcome by the above‐described stratification treatment. When desiccation was preceded by high temperatures, seeds better overcame dormancy. Stress treatments killed 5–10% of seeds. This study suggests that the seeds of species with complex morphophysiological dormancy ( MPD ) levels are sensitive to desiccation in early embryo development stages, as opposed to the seeds of species with deep simple epicotyl MPD , which better tolerate water stress.

Topic: Seed Germination and Physiology
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Neumann′s tumor in new born

Congenital epulis (CE) also known as granular cell tumor of new born was first described by Neumann in the year 1871. Most frequent location includes maxillary alveolar ridge with a female preponderance up to 8 times more than males. These tumors are usually small and can be solitary or multiple, pedunculated or protuberant mucosa covered nodules presenting at birth. Multiple theories have been proposed for their origin. Though, it may cause panic at birth they are indolent and regress spontaneously. Rare cases require surgical intervention in the neonatal period when symptomatic, causing difficulties in respiration or deglutition. We describe a case of CE in a 2-day-old female neonate, who presented with pink protuberant mass in the anterior alveolar ridge of maxilla. The mass was symptomatic and surgery was indicated. The mass was excised and the benign nature was confirmed by histopathology.

Topic: Tumors and Oncological Cases
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
TO EVALUATE CLINICALLY THE OUTCOME OF LICHTENSTEIN REPAIR FOR INGUINAL HERNIA IN A TERTIARY CARE CENTRE

BACKGROUND&#13;\nThe first hernia repair was done by Bassini 100 years ago and all the next surgical methods and their modifications use a suture &#13;\nof the tissues under the tension. Lichtenstein technique challenged the concept of both the plication-darn technique and the &#13;\nShouldice operation and he introduced a tension free method of hernia repair for inguinal hernia with polypropylene prosthetic &#13;\nmesh and it did not rely upon muscle tendon union.&#13;\nMATERIALS AND METHODS&#13;\nAll 54 patients above 18 years belongs to both genders diagnosed to have inguinal hernia were included. All were underwent &#13;\nLichtenstein’s hernioplasty and different parameters were studied. Patients below 18 years and who came with recurrent inguinal &#13;\nhernia were excluded in this study.&#13;\nRESULTS&#13;\nAll the 54 patients who had been operated and monitored were all from low socioeconomic status and only a few had comorbidities and who had to be stabilised before surgery. The operation time and the intersurgeon variation time were noted &#13;\nand the average duration of surgery was calculated. Postoperatively, all the patients were monitored with visual analogue pain &#13;\nscale and checked. Follow up was done for 4 months and patients were enquired for complications and results were noted. In &#13;\nour study Lichtenstein’s hernioplasty surgery that had been done for inguinal hernia, it is found that postoperative complications &#13;\nrate were very much lower except for the high incidence of seroma, which is due to the increased operating time of the surgeons. &#13;\nThe limitations of this study was that the follow up time was short compared to other studies.&#13;\nCONCLUSION&#13;\nIn our study, haematoma and seroma were the only two postoperative complications, which occurred following Lichtenstein &#13;\nrepair for inguinal hernia. In that, incidence of seroma was found to be high.

Topic: Hernia repair and management
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Subtype-Specific Regulation of Receptor Internalization and Recycling by the Carboxyl-Terminal Domains of the Human A<sub>1</sub>and Rat A<sub>3</sub>Adenosine Receptors:  Consequences for Agonist-Stimulated Translocation of Arrestin3

In this study, we have characterized the differential effects on inhibitory adenosine receptor (AR) trafficking of disrupting predicted sites for palmitoylation and phosphorylation within each receptor's carboxyl terminus. While a Cys(302,305)Ala-mutated rat A(3)AR mutant internalizes significantly faster than the wild-type (WT) receptor in response to agonist exposure, analogous mutation of the human A(1)AR (Cys(309)Ala) had no effect on receptor internalization. Moreover, unlike the WT A(3)AR, the entire pool of internalized mutant A(3)AR is able to recycle back to the plasma membrane following agonist removal. These properties do not reflect utilization of an alternative trafficking pathway, as internalized WT and mutant A(3)ARs both accumulate into transferrin receptor-positive endosomal compartments. However, receptor accumulation into endosomes is dependent upon prior G-protein-coupled receptor kinase (GRK)-mediated phosphorylation of the receptor's carboxyl terminus, as replacement of the carboxyl-terminal domain of the human A(1)AR with the 14 GRK-phosphorylated amino acids of the rat A(3)AR confers rapid agonist-mediated endosomal accumulation of the resulting chimeric A(1)CT3AR. Sensitivity to GRK-mediated phosphorylation also dictates the distinct redistribution of arrestin3 observed upon agonist exposure. Thus, while the nonphosphorylated A(1)AR redistributes arrestin3 from the cytoplasm to punctate clusters at the plasma membrane, GRK-phosphorylated WT and Cys(302,305)Ala-mutated A(3)ARs, as well as the A(1)CT3AR chimera, each induce the redistribution of arrestin3 into punctate accumulations both at the plasma membrane and within the cytoplasm. Neither the human A(1)AR nor the rat A(3)AR colocalized with arrestin3 under basal or agonist-stimulated conditions. Together, these results demonstrate that inhibitory AR-mediated changes in arrestin3 distribution are subtype-specific, with specificity correlating with the sensitivity of the receptor's carboxyl-terminal domain to GRK phosphorylation. In the case of the rat A(3)AR, sensitivity to GRK-mediated internalization appears to be regulated in part by the integrity of putative palmitate attachment sites upstream of its GRK phosphoacceptor sites.

Topic: Receptor Mechanisms and Signaling
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
FINANCIAL ARCHITECTURE ADAPTATION OF ENTERPRISES: QUANTITATIVE DOMINANTS IN THE CYCLICAL ECONOMIC DEVELOPMENT

The article presents a study on the properties of adaptation of business financial architecture in a cyclical development of the economy. The importance of the ability to regulate both individual components and the architecture as a whole in accordance with the stages of the business cycle in terms of reducing business and financial constraints and reducing capital costs is emphasized. The adaptation of financial architecture of large metallurgical companies for the period of business cycle in Ukraine is considered. The speed of the dynamic adjustment of architecture based on key industrial enterprises in Ukraine, as well as the acceleration for models of adaptive changes are estimated.

Topic: Economic Issues in Ukraine
Subfield: General Economics, Econometrics and Finance
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Macrophage activities in sarcoma 180-bearing mice and EL4-bearing mice.

Four types of macrophage activities were studied in sarcoma 180-bearing ICR mice and EL4-bearing C57BL mice. Sarcoma 180 cells grow very slowly and do not metastasize, while EL4 cells grow very rapidly and metastasize rapidly to the liver. Chemotactic activity of macrophages was significantly reduced from an early stage in both sarcoma 180-bearing ICR mice and EL4-bearing C57BL mice as compared with that in normal mice. Digestive activity, which was determined by following O2- production by chemiluminescence measurements was also reduced from an early stage in tumor-bearing mice, whereas no reduction of engulfment activity of microorganisms was observed until an advanced stage in both sarcoma 180-bearing mice and EL4-bearing mice. In contrast enhancement activity of macrophages in the blastogenic response of spleen lymphocytes to bacterial lipopolysaccharide was retained at the normal level at the early stage of the tumor graft and was reduced in later stages. These results suggest that activities of Ia-negative macrophages were at first depressed generally in tumor-bearing hosts and later the activities of Ia-positive macrophages were depressed by factor(s) which might be produced by tumor cells.

Topic: Immune cells in cancer
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Relational Blocks: A Visual Dataflow Language for Relational Web-Applications

Many Web-applications can be characterized as "relational". In this paper we show that developers can greatly benefit from relational blocks, a visual, domain-specific, dataflow language that is designed to facilitate the construction of such web-applications. We define the relational blocks visual language, discuss our WebRB implementation, and show how WebRB is used to construct non-trivial web-pages.

Topic: Multimedia Communication and Technology
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
In Vitro Screening for ToxCast Chemicals Binding to Thyroxine-Binding Globulin

Thyroid hormone (TH) carrier proteins play an important role in distributing TH to target tissue as well as maintaining the balance of free versus bound TH in the blood. Interference with the TH carrier proteins has been identified as a potential mechanism of thyroid system disruption. To address the lack of data regarding chemicals binding to these carrier proteins and displacing TH, a fluorescence-based <i>in vitro</i> screening assay was utilized to screen over 1,400 chemicals from the U.S. EPA's ToxCast phase1_v2, phase 2, and e1k libraries for competitive binding to one of the carrier proteins, thyroxine-binding globulin. Initial screening at a single high concentration of 100 μM identified 714 chemicals that decreased signal of the bound fluorescent ligand by 20% or higher. Of these, 297 produced 50% or greater reduction in fluorescence and were further tested in concentration-response (0.004 to 150 μM) to determine relative potency. Ten chemicals were found to have EC50 values <1 μM, 63 < 10 μM, and 141 chemicals between 10 and 100 μM. Utilization of this assay contributes to expanding the number of <i>in vitro</i> assays available for identifying chemicals with the potential to disrupt TH homeostasis. These results support ranking and prioritization of chemicals to be tested <i>in vivo</i> to aid in the development of a framework for predicting <i>in vivo</i> effects from <i>in vitro</i> high-throughput data.

Topic: Carcinogens and Genotoxicity Assessment
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Josephson-based full digital bridge for high-accuracy impedance comparisons

This paper describes a Josephson-based full digital impedance bridge capable of comparing any two impedances, regardless of type (R-C, R-L, or L-C), over a large frequency range (from 1 kHz to 20 kHz). At the heart of the bridge are two Josephson arbitrary waveform synthesizer systems that offer unprecedented flexibility in high-precision impedance calibration, that is, it can compare impedances with arbitrary ratios and phase angles. Thus this single bridge can fully cover the entire complex plane. In the near future, this type of instrument will considerably simplify the realization and maintenance of the various impedance scales in many National Metrology Institutes around the world.

Topic: Advanced Electrical Measurement Techniques
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Analyses of transport in the upper soil layer and interpretation of caisson experiments

The transport experiments conducted by Los Alamos National Laboratory in an intermediate-scale caisson are described. The results suggest that the solute spreading pattern has been dominated by the effect of spatial variability of hydraulic properties. A stochastic model of horizontally varying velocity distribution is employed in order to interpret the concentration data. A satisfactory match between the measured solute mass cross-sectional transfer in saturated flow and model is achieved for a standard deviation of the logconductivity of 1.2. The model may serve for interpretation of transport in unsaturated flow and for reactive solutes. 11 refs., 7 figs.

Topic: Groundwater flow and contamination studies
Subfield: Environmental Engineering
Field: Environmental Science
Domain: Physical Sciences
"In the Cause of Liberty." The American Civil War Center at Historic Tredegar, Richmond, Va. http://www.tredegar.org/

Journal Article "In the Cause of Liberty." The American Civil War Center at Historic Tredegar, Richmond, Va. http://www.tredegar.org/ Get access Andrew J. Torget Andrew J. Torget University of VirginiaCharlottesville, Virginia Search for other works by this author on: Oxford Academic Google Scholar Journal of American History, Volume 94, Issue 3, December 2007, Pages 894–896, https://doi.org/10.2307/25095154 Published: 01 December 2007

Topic: Vietnamese History and Culture Studies
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
The University of Kansas Applied Sensing Program: An operational perspective

The Kansas applied remote sensing (KARS) program conducts demonstration projects and applied research on remote sensing techniques which enable local, regional, state and federal agency personnel to better utilize available satellite and airborne remote sensing systems. As liason with Kansas agencies for the Earth Resources Laboratory (ERL), Kansas demonstration project, KARS coordinated interagency communication, field data collection, hands-on training, and follow-on technical assistance and worked with Kansas agency personnel in evaluating land cover maps provided by ERL. Short courses are being conducted to provide training in state-of-the-art remote sensing technology for university faculty, state personnel, and persons from private industry and federal government. Topics are listed which were considered in intensive five-day courses covering the acquisition, interpretation, and application of information derived through remote sensing with specific training and hands-on experience in image interpretation and the analysis of LANDSAT data are listed.

Topic: Geographic Information Systems Studies
Subfield: Geography, Planning and Development
Field: Social Sciences
Domain: Social Sciences
Short-Term Clinical Results of Transoral Endoscopic Laryngo-pharyngeal Surgery for Superficial Laryngopharyngeal Carcinoma

内視鏡的咽喉頭手術 (endoscopic laryngo-pharyngeal surgery: ELPS) は頭頸部表在癌に対する経口的切除法の一つである. 当院では彎曲型喉頭鏡を用いて咽喉頭を展開後, 消化器内視鏡医が拡大内視鏡により病変の観察を行い, 術者である耳鼻咽喉科・頭頸部外科医が先端可変式の高周波ナイフを用いて病変を切除している. 切除の際, 病変周囲や粘膜下への局注は消化器内視鏡医が内視鏡の鉗子口を経由して局注針を用いて行っており, 場合によっては切開や助手的な手技も行う. 耳鼻咽喉科・頭頸部外科医と消化器内視鏡医の連携が重要である. 2014年8月~2017年12月の間に頭頸部表在癌例に対して施行した計50回の ELPS における40例57病変を対象に後方視的に検討した. 原発部位は下咽頭: 中咽頭: そのほかが43: 7: 7病変であった. 1病変の平均切除時間は59分で, 病理学的切除端は pHM0: pHM1: pHMX が27: 16: 14病変, pVM0: pVM1 が56: 1病変であった. 経口摂取開始日の中央値は1日であった. 術後2例でそれぞれ著明な喉頭浮腫と誤嚥により気管切開を行った. 局所再発を3例, 頸部リンパ節再発を4例で認め, 2例で他病死したがそのほか全例非担癌で生存中である. 当院では耳鼻咽喉科・頭頸部外科医と消化器内視鏡医が連携することで, 良好な成績で ELPS を行うことが可能であった.

Topic: Dysphagia Assessment and Management
Subfield: Speech and Hearing
Field: Health Professions
Domain: Health Sciences
A case of fatal gastrointestinal hemorrhage in granulomatosis with polyangiitis

Although granulomatosis with polyangiitis (GPA) can affect any organ, gastrointestinal (GI) involvement is uncommon. Moreover, death from massive GI hemorrhage is a rare entity, with few cases described in the literature. In our report, we present a case of a patient with GPA who developed massive ulcerative bleeding, which ultimately proved fatal. Given the paucity of reports available, the significant potential for morbidity, and the fact that concurrent immunosuppressive therapy may themselves exacerbate the risk of bleeding, we reviewed 49 case reports of patients with GPA and GI involvement from 1982 to June 2016 in an attempt to shed light on a little seen sequelae that warrants a high index of suspicion.

Topic: Vasculitis and related conditions
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Construction of a hypoxia responsive upconversion nanosensor for tumor imaging by fluorescence resonance energy transfer from carbon dots to ruthenium complex

Hypoxia responsive upconversion nano-aggregates are synthesized which can be excited by NIR light to give oxygen dependent phosphorescence emission <italic>via</italic> the FRET process.

Topic: Luminescence and Fluorescent Materials
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Upper Urinary Tract Cancer—Challenges for the Urologist

No AccessJournal of UrologyEditorial1 Jul 2007Upper Urinary Tract Cancer—Challenges for the Urologistis companion ofSquamous Cell Carcinoma of the Renal Pelvis and Ureter: Incidence, Symptoms, Treatment and OutcomeMalignant Ureteral Obstruction: Outcomes After Intervention. Have Things Changed? Peter J. Bostrom and Mark S. Soloway Peter J. BostromPeter J. Bostrom More articles by this author and Mark S. SolowayMark S. Soloway More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2007.04.014AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Upper Urinary Tract Cancer—Challenges for the Urologist." The Journal of Urology, 178(1), pp. 12–13 References 1 : Clonality of multifocal urothelial carcinomas: 10 years of molecular genetic studies. Int J Cancer2002; 101: 1. Google Scholar 2 : The outcome of patients with advanced pure squamous or mixed squamous and transitional urothelial carcinomas following platinium-based chemotherapy. Anticancer Res2006; 26: 3865. Google Scholar 3 : Cancer Pain Relief and Palliative Care. Geneva, Switzerland: World Health Organization1990: 11. Google Scholar 4 : Medical and surgical palliative care of patients with urological malignancies. J Urol2005; 174: 1177. Link, Google Scholar Department of Urology, Miller School of Medicine, University of Miami, Miami, Florida© 2007 by American Urological AssociationFiguresReferencesRelatedDetailsRelated articlesJournal of Urology10 May 2007Squamous Cell Carcinoma of the Renal Pelvis and Ureter: Incidence, Symptoms, Treatment and OutcomeJournal of Urology11 May 2007Malignant Ureteral Obstruction: Outcomes After Intervention. Have Things Changed? Volume 178Issue 1July 2007Page: 12-13 Advertisement Copyright & Permissions© 2007 by American Urological AssociationMetricsAuthor Information Peter J. Bostrom More articles by this author Mark S. Soloway More articles by this author Expand All Advertisement PDF downloadLoading ...

Topic: Bladder and Urothelial Cancer Treatments
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Design of Underwater Acoustic Modem for Short Range Sensor Network

This paper presents the design consideration, implementation details and initial experimental results of our modem. This paper also discusses the various modulation technique like ASK,FSK. This design uses commercial ultrasonic transducer of 200kHz bandwidth. Massage from transmitter can be displayed in visual format as well as it can be analyzed using different simulation tools at base station. Under water modem consists of three component i) An underwater transducer ii) An analog transceiver (matching pre-amplifier and amplifier), iii) A digital platform for control and signal processing. In this paper comparison of results of communication with ASK,FSK modulation technique, microcontroller & FPGA.

Topic: Underwater Vehicles and Communication Systems
Subfield: Ocean Engineering
Field: Engineering
Domain: Physical Sciences