jimnoneill/paper-to-field-training huggingface dataset:
LHD Magnetics #4952.1

Magnetic measurements for estimating global parameters and for magnetohydrodynamic (MHD) study to introduce diamagnetic flux measurement and MHD mode analysis. Various types of magnetic sensors are used; Rogowski coils and magnetic probes inside and ourside the LHD vacuum vessel.

Topic: High-Energy Particle Collisions Research
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
A comparative study on health related quality of life in hemodialysis patients and healthy people

Introduction: End stage renal disease affects many aspects of the hemodialysis patients life, and finally affects their health relate quality of life .The aim of this study was comparison between the hemodialysis patients and healthy population in the Fatima Zahra and Imam Khomeini hospital of Sari.(2007-2008). Methods: We interviewed and completed the SF-36 questionnaires for 100 hemodialysis patients and 100 healthy people and collected data were analyzed by SPSS 15 software, with McNemar, Pearson, chi- square, and independent t-test. Results: Mean age for patients was 55.41 and for healthy people 55.16 years. Patients were mostly with low education, urban residents, and intermediate socio-economic class. Mental health score was the top and the role emotional scores the least aspects of patients' quality of life. In addition there was significant difference between patients and healthy people scores on every subscale in quality of life. Conclusions: The results showed that there is necessity for socioeconomic support and counseling activities for patients with hemodialysis.

Topic: Health and Wellbeing Research
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
MD files (psf, pdb, and toppar) for the trajectories of the glycoprotein receptors FSHR and LHCGR.

PSF and PDB files for trajectories on FSHR and LHCGR in SDPC lipids. Top and par parameters for charmm36m included. PDB files and trr files include only backbone atoms. All frames were fitted to the to the transmembrane domains.

Topic: Medical Imaging Techniques and Applications
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Multifocality and Bilaterality of Papillary Thyroid Microcarcinoma

In cases of PTMCs, the incidence of multifocal tumors is high. However, additional tumor foci are too small to be diagnosed preoperatively, especially under the recent guidelines on radiologic screening tests for papillary thyroid carcinoma. Multifocal PTMCs have high risk of bilateral tumors, necessitating more extensive surgery or more thorough follow-up.

Topic: Thyroid Cancer Diagnosis and Treatment
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
E06884: Three letters of Pope Vitalian I (657-72), of disputed authenticity, condemn the removal of relics of *Benedict (of Nursia, monk, ob. 547, S01727) from Montecassino, central Italy, and their translation to Fleury (central Gaul), in c. 660. Written in Latin in Rome.

Vitalian I, Letter 6<br><br>Extract:<br><br>Audivimus, quod sine gravi dolore loqui non possumus, quemdam vestri coenobii gyrovagum, Augulfum nomine, suggestione diabolica Casinum venisse, et effracto beati Benedicti sepulcro, ejus reliquias diminuisse.<br><br>We have heard, and we cannot say this without grave sorrow, that a certain wandering monk of yours called Augulf, at the suggestion of the devil, came to Montecassino, smashed open the tomb of Benedict and took some of [lit: diminished] his relics. <br><br>Vitalian continues to condemn this violation and insists that the relics be returned to Montecassino. <br><br>Vitalian I, Letter 7<br><br>Addressed to Clovis, king of the Franks. This letter condemns the theft in the same terms as the previous letter and informs Clovis of the papal decision to excommunicate both Augulf and his ‘false’ abbot Mommulus. <br><br>Vitalian I, Letter 9<br><br>Addressed to the bishops of Spain and Gaul. This letter also condemns the theft and informs these bishops of the excommunication of Augulf and Mommulus. <br><br>Text: Patrologia Latina 87. Translation and Summary: Frances Trzeciak.<br><br>

Topic: Microbial Natural Products and Biosynthesis
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Preventive effect of Chyavanprash against steroid induced cataract in the developing chick embryo

The anticataract potential of Chyavanprash, a popular herbal formulation of India was investigated in hydrocortisone-induced cataract in the developing chick embryo. Aqueous extracts of Chyavanprash (3% and 10%) were applied at 3, 10 and 20 h after hydrocortisone administration. The incidence of advanced opacity (stage 4 and 5) was 33% after treatment with 3% extract, and 16.5% after treatment with 10% extract, compared with 96.6% in the control group. The aqueous extracts (3% and 10%) significantly prevented depletion of glutathione. Levels were 1.8 ± 0.22 and 1.96 ± 0.33 μmol/g wet weight of lens, respectively compared with 1.06 ± 0.073 in the control group. In conclusion Chyavanprash, which is widely used in India as an anti-aging formula, provides significant protection against HC-induced cataract in the developing chick embryo. © 1998 John Wiley & Sons, Ltd.

Topic: Plant-based Medicinal Research
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
The nature of the carcinoma associated with ulcerative colitis

1Scott and White Clinic, Temple, Texas aSenior Consultant in Gastroenterology Read at the meeting of the American Proctologic Society, Miami Beach, Florida, April 30 to May 3, 1962.

Topic: Inflammatory Bowel Disease
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Size-Aware Cache Management for Compressed Cache Architectures

A practical way to increase the effective capacity of a microprocessor's cache, without physically increasing the cache size, is to employ data compression. Last-Level Caches (LLC) are particularly amenable to such compression schemes, since the primary purpose of the LLC is to minimize the miss rate, i.e., it directly benefits from a larger logical capacity. In compressed LLCs, the cacheline size varies depending on the achieved compression ratio. Our observations indicate that this size information gives useful hints when managing the cache (e.g., when selecting a victim), which can lead to increased cache performance. However, there are currently no replacement policies tailored to compressed LLCs; existing techniques focus primarily on locality information. This article introduces the concept of size-aware cache management as a way to maximize the performance of compressed caches. Upon analyzing the benefits of considering size information in the management of compressed caches, we propose a novel mechanism-called Effective Capacity Maximizer (ECM)-to further enhance the performance and energy consumption of compressed LLCs. The proposed technique revolves around four fundamental principles: ECM Insertion (ECM-I), ECM Promotion (ECM-P), ECM Eviction Scheduling (ECM-ES), and ECM Replacement (ECM-R). Extensive simulations with memory traces from real applications running on a full-system simulator demonstrate significant improvements compared to compressed cache schemes employing conventional locality-aware cache replacement policies. Specifically, our ECM shows an average effective capacity increase of 18.4 percent over the Least-Recently Used (LRU) policy, and 23.9 percent over the Dynamic Re-Reference Interval Prediction (DRRIP) [1] scheme. This translates into average system performance improvements of 7.2 percent over LRU and 4.2 percent over DRRIP. Moreover, the average energy consumption is also reduced by 5.9 percent over LRU and 3.8 percent over DRRIP.

Topic: Parallel Computing and Optimization Techniques
Subfield: Hardware and Architecture
Field: Computer Science
Domain: Physical Sciences
Episcopal Church Home For Children Records - Accession 31

This collection is a valuable source on the Church’s historical effort to extend its services for the social improvement of South Carolina (in this case the Episcopal Diocese’s program for destitute children.) While there is information on the Episcopal Home for Children from its beginning in 1850 to 1967, the actual records do not start until 1866. A centennial history of the Episcopal Home will serve as an aid and general guideline to the researcher. (See box 1, folder 1). The collection consists of minutes, reports of the annual meeting, general correspondence, superintendent’s records, health records, attendance registers, financial records, newsletters (both bound and unbound), and photographs. See the Caroliniana File for the Church Home newsletters.

Topic: Pentecostalism and Christianity Studies
Subfield: Religious studies
Field: Arts and Humanities
Domain: Social Sciences
The Role of the Statistical Laboratory in the Teaching of Statistics

Summary The object of this article is to discuss the role of the statistical laboratory in the teaching of statistics. At the same time it is intended to bring to the attention of the reader the importance of the developing of a statistical laboratory in all centres of education where statistics is included in the curriculum. The size of each laboratory, of course, will depend upon the amount and level of statistics taught. A wider use of the laboratory is advocated to include such facilities as a ‘Statistical Library’, a ‘Data Bank’ and the publication of a ‘Statistical Bulletin’, etc. The laboratory should also house a comprehensive selection of equipment ranging from the simple to the more sophisticated, thus offering opportunities to users with varied statistical interests. In conclusion it has been suggested that proper statistical training with the help of a well equipped laboratory will not only provide better understanding of the subject but also prevent the incorrect uses of the techniques.

Topic: Statistics Education and Methodologies
Subfield: Statistics and Probability
Field: Mathematics
Domain: Physical Sciences
Design and Evaluation of an Augmented Reality-Based Exergame System to Reduce Fall Risk in the Elderly

Falls are a major public health concern in today’s aging society. Virtual reality (VR) technology is a promising method for reducing fall risk. However, the absence of representations of the user’s body in a VR environment lessens the spatial sense of presence. In terms of user experience, augmented reality (AR) can provide a higher degree of presence and embodiment than VR. We developed an AR-based exergame system that is specifically designed for the elderly to reduce fall risk. Kinect2.0 was used to capture and generate 3D models of the elderly and immerse them in an interactive virtual environment. The software included three functional modules: fall risk assessment, cognitive–motor intervention (CMI) training, and training feedback. The User Experience Questionnaire (UEQ-S) was used to evaluate user experience. Twenty-five elders were enrolled in the study. It was shown that the average scores for each aspect were: pragmatic quality score (1.652 ± 0.868); hedonic quality score (1.880 ± 0.962); and overall score was 1.776 ± 0.819. The overall score was higher than 0.8, which means that the system exhibited a positive user experience. After comparing the average score in a dataset product of UEQ-S Data Analysis Tool, it was found that the pragmatic quality aspect was categorized as good, while the hedonic quality aspect was categorized as excellent. It revealed a positive evaluation from users.

Topic: Stroke Rehabilitation and Recovery
Subfield: Rehabilitation
Field: Medicine
Domain: Health Sciences
[Mucosa dimensions and cell proliferation in intestinal organ cultures with and without inhibition of cholesterol synthesis].

The changes in the structure and proliferative activity of rabbit ileal mucosa have been studied with morphometric and stathmokinetic techniques during 24 h organ culture. Under control conditions the villus base diameter and villus height decreased by 34 and 53%, respectively, whereas the number of villi per mm2 remained constant. The reduction of crypt depth was less pronounced than the loss in villus height, leading to a decrease in the villus height to crypt depth ratio from 3.4 to 2.3. The likely reason for this culture induced hypoplasia was a significant drop in mitotic activity as early as 2 h after starting the culture. Inhibition of HMG-CoA reductase, the key enzyme of cholesterogenesis, lead to a further reduction in mucosal dimensions and a near complete suppression of crypt cell regeneration. These data imply that despite the well-known preservation of differentiated function mucosal cell renewal during organ culture is impaired.

Topic: Clinical Nutrition and Gastroenterology
Subfield: Nutrition and Dietetics
Field: Nursing
Domain: Health Sciences
Data from IL3-Driven T Cell–Basophil Crosstalk Enhances Antitumor Immunity

&lt;div&gt;Abstract&lt;p&gt;Cytotoxic T lymphocytes (CTL) are pivotal in combating cancer, yet their efficacy is often hindered by the immunosuppressive tumor microenvironment, resulting in CTL exhaustion. This study investigates the role of interleukin-3 (IL3) in orchestrating antitumor immunity through CTL modulation. We found that intratumoral CTLs exhibited a progressive decline in IL3 production, which was correlated with impaired cytotoxic function. Augmenting IL3 supplementation, through intraperitoneal administration of recombinant IL3, IL3-expressing tumor cells, or IL3-engineered CD8&lt;sup&gt;+&lt;/sup&gt; T cells, conferred protection against tumor progression, concomitant with increased CTL activity. CTLs were critical for this therapeutic efficacy as IL3 demonstrated no impact on tumor growth in Rag1 knockout mice or following CD8&lt;sup&gt;+&lt;/sup&gt; T-cell depletion. Rather than acting directly, CTL-derived IL3 exerted its influence on basophils, concomitantly amplifying antitumor immunity within CTLs. Introducing IL3-activated basophils retarded tumor progression, whereas basophil depletion diminished the effectiveness of IL3 supplementation. Furthermore, IL3 prompted basophils to produce IL4, which subsequently elevated CTL IFNγ production and viability. Further, the importance of basophil-derived IL4 was evident from the absence of benefits of IL3 supplementation in IL4 knockout tumor-bearing mice. Overall, this research has unveiled a role for IL3-mediated CTL–basophil cross-talk in regulating antitumor immunity and suggests harnessing IL3 sustenance as a promising approach for optimizing and enhancing cancer immunotherapy.&lt;/p&gt;&lt;p&gt;&lt;a href="https://aacrjournals.org/cancerimmunolres/article-abstract/doi/10.1158/2326-6066.CIR-24-0395" target="_blank"&gt;&lt;i&gt;See related Spotlight, p. 798&lt;/i&gt;&lt;/a&gt;&lt;/p&gt;&lt;/div&gt;

Topic: Immune Cell Function and Interaction
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
POST-BUCKLING OF AN ELASTIC COLUMN WITH VARIOUS ROTATIONAL END RESTRAINTS

In this technical note, the post-buckling behavior of a simply supported elastic column with various rotational end conditions of the supports is investigated. The compressive force is applied at the tip of the column. The characteristic equation for solving the critical loads is obtained from the boundary value problem of linear systems. In the post-buckling state, a set of nonlinear differential equations with boundary conditions is established and numerically solved by the shooting method. The interesting features associated with this problem such as the limit load point, snap-through phenomenon and the secondary bifurcation point will be highlighted herein.

Topic: Composite Structure Analysis and Optimization
Subfield: Mechanics of Materials
Field: Engineering
Domain: Physical Sciences
An Expeditious Route to Both Enantiomers of All Carbon Quaternary Stereocenters at C-3 Carbon of Lactams via [3,3]-Sigmatropic Rearrangement: Total Synthesis of (−)-Physostigmine

A diastereoselective route to all carbon quaternary stereocenters at the C-3 position of cyclic lactams has been developed via Johnson-Claisen rearrangement of γ-hydroxy-α, β-unsaturated lactams. It has been observed that olefin geometry plays an important role in the development of the absolute stereochemistry of the product. The dependence of the product configuration on the olefin geometry is explained by postulating probable transition states. The success of this method has been shown for the multigram scale synthesis of these substituted lactams from commercially available cheap starting materials. The synthetic usefulness of this method is also demonstrated by carrying out the total synthesis of (-)-physostigmine.

Topic: Asymmetric Synthesis and Catalysis
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Past and Present Scholarship on The Politeia of the Epirotes and a New Book on the History of Molossia

Piccinini Jessica. Past and Present Scholarship on The Politeia of the Epirotes and a New Book on the History of Molossia. In: L'antiquité classique, Tome 84, 2015. pp. 227-235.

Topic: Classical Antiquity Studies
Subfield: Anthropology
Field: Social Sciences
Domain: Social Sciences
Comparison of Selected Physiological and Personality Variables in Regular and Nonregular Adult Male Exercisers

Abstract The purpose of this study was to compare regular and nonregular adult exercisers on selected physiological and personality measures over a four-year period. Forty-eight participants in the 1971 Purdue Adult Fitness Program were retested four years later. As a result three groups of 16 subjects each were established, based on responses to an Exercise and Leisure Questionnaire. Relevant physiological data were collected and physical fitness scores were obtained for each subject using the criterion of Ismail and others. Personality traits were assessed using the same form of the Cattell 16 Personality Factor Questionnaire as both pre- and posttests. The data were analyzed at both test periods using the ANOVA technique. The effect of different activity levels was assessed by several fitness parameters such as percent lean body weight, resting and submaximal heart rates, submaximal RQ, [Vdot]O2 max, and physical fitness score. The two regularly active groups increased significantly in physical fitness over the four-year period. At both test periods the regularly active group was significantly more confident (Factor O) than the other two groups, indicating that the relationship between physical fitness and self-confidence is stable.

Topic: Physical Activity and Health
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
‘I Interact Therefore I Am’: The Self as a Historical Product of Dialectical Attunement

In this article, moving from being to becoming, we construe the 'self' as a dynamic process rather than as a static entity. To this end we draw on dialectics and Bayesian accounts of cognition. The former allows us to holistically consider the 'self' as the interplay between internalization and externalization and the latter to operationalize our suggestion formally. Internalization is considered here as the co-construction of bodily hierarchical models of the (social) world and the organism, while externalization is taken as the collective transformation of the world. We do not consider these processes as sequentially linked, but rather as a dialectic between the collective and the individual. This leads us to the suggestion of the self as a historical product of dialectical attunement across multiple time scales, from species evolution and culture to individual development and everyday learning. Subsequently, we describe concrete means for empirically testing our proposal in the form of two-person psychophysiology and multi-level analyses of intersubjectivity. Taken together, we suggest that a fine-grained analysis of social interaction might allow us to reconsider the 'self' beyond the static individual, i.e. how it emerges and manifests itself in social relations. Such an approach, we believe, could be relevant in multiple fields, from ethics and psychiatry to pedagogy and artificial intelligence.

Topic: Embodied and Extended Cognition
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Metabolism and Effects of Synthetic Gonadotropin-Releasing Hormone (GnRH) in Children and Adults*

To compare the metabolism and effects of synthetic GnRH (Parke-Davis CI-785) in children and adults, 24 children were given 10 μg GnRH/m2 iv; 5 adult male volunteers randomly received 1, 10, 25 and 100 μg GnRH/m2 iv at weekly intervals. Blood samples were withdrawn at frequent intervals during the 1 hr before and 4 hr after injection. GnRH concentrations were determined by a highly specific radioimmunoassay which utilizes Niswender antiserum #R-42 and 125I-GnRH purified by polyacrylamide disc gel electrophoresis. Sensitivity of this assay is 1 pg/tube or 5 pg/ml of unextracted plasma. Serum LH and FSH were determined by radioimmunoassay. No correlation was found between physiological state or serum gonadotropin concentrations, and endogenous GnRH values. Indeed, most plasma samples were at or below the sensitivity of the GnRH assay. Maximum GnRH concentrations occurred at +1 or +2 min and were significantly greater in children (4.02 ± 0.33 (se) ng/ml) than adults (2.05 ± 0.37 (se) ng/ml) given GnRH iv at 10 μg/m2. The plasma disappearance curve of GnRH in children and adults could be described by a double exponential function with an average distribution phase half-life of 2.5 min and a highly variable elimination phase half-life of approximately 20 min. Initial distribution volumes and plasma clearance rates were also similar: children 8.7 ± 0.8 (se) % body weight and 657 ± 42 (se) l/d/m2; adults 8.5 ± 2.2 (se) % body weight and 682 ± 44 (se) l/d/m2. In adults, plasma clearance decreased progressively with increasing doses of GnRH. Despite greater maximum concentrations of GnRH, prepubertal children had bluntedserum LH responses compared to adult males. Serum FSH responses were similar in prepubertal, pubertal and adult males, but greatly exaggerated responses were seen in some prepubertal females. Linear log dose-responses for LH and FSH were found between 1.0 and 100 μg/m2 doses of GnRH. Significant LH release occurred during all tests inadult males with only one exception at the 1.0 μg/m2 dose. Significant FSH release was not uniformly observed at any dose. These data indicate that: 1) endogenous concentrations of GnRH are less than earlier reports; 2)children and adults metabolize GnRH similarly, but plasma clearance is dose-dependent; 3) gonadotropin responses to iv GnRH are dependent on age, sex and degree of sexual maturation.

Topic: Sexual Differentiation and Disorders
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Cloning,Expression and Establishment of the ELISA Detection Method of the S1 Protein of SARS

Serological testing of SARS cases is very important for diagnosis and treatment of clinical patients,for control of SARS epidemics and the epidemiological study.A highly sensitive,specific and convenient indirect enzyme-linked immunosorbent assay(ELISA) was established by using the S1 protein of SARS coronavirus as the antigen.The S1 proteins were highly expressed independently using pGEX-4T1 expression system,and the target protein was purified by the inclusion bodies.The inclusion bodies were washed,lysed,refolded to a purity of 75?%.An indirect ELISA for the detection of antibodies against people was developed using the recombinant S1 protein expressed highly in E.coli as antigen.The best condition which is filtrated through experimentation of veaction is 5?μg per hole.Using the antigen expressed by purifying E.coli cover the board of enzyme-linked and obturate it with bovine serum then dilute uninspected serum with liquor of E.coli.The results show that the assay is characterized by its specificity,simplicity and economical cost.

Topic: SARS-CoV-2 and COVID-19 Research
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences