jimnoneill/paper-to-field-training huggingface dataset:
Motivational intermediaries of self-regulation among university students

Purpose The concept of self-regulated learning (SRL) has become increasingly important in higher educational institutes seeking to provide students with a holistic education. It is important for students entering, and faculty within higher education, to understand whether future time perspective (FTP) or self-efficacy is more predictive of self-regulation. The paper aims to discuss these issues. Design/methodology/approach Through the use convenience sampling, data were collected via an online survey from 130 undergraduate students attending universities in the United Arab Emirates (UAE). Data were analysed using regression analysis and inferential measures identifying themes in participants study habits in order to examine whether it is FTP or self-efficacy that more strongly predicts SRL behaviours. Findings Results suggest that self-efficacy is a much stronger predictor of SRL in undergraduate students than goal setting, as measured by FTP. Student’s most deficient SRL behaviours related to reading and comprehension of texts prescribed across modules. Research limitations/implications Due to the fact that only an adjusted 33 per cent of self-regulation was predicted by the two variables under consideration, researchers are encouraged to identify further variables that may predict students SRL. Practical implications This paper seeks to support both students and faculty in how to draw on SRL in order to optimize students’ success in higher education. Originality/value The current research supports the identification of learning behaviours specific to branch campuses in a Middle-Eastern context.

Topic: Psychological and Temporal Perspectives Research
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
The Affect of Application Volume and Deposition Aids on Droplet Spectrum and Deposition for Aerial Applications

A field study was conducted to determine the influence of application volume and tank mix deposition aids on droplet spectrum and deposition for a fixed wing aerial application. The study involved using a turbine powered aircraft to apply four products designed to improve deposition in 9 and 28 L/ha tank mix solutions. Kromekote papers were used to collect the data at low, medium, and high positions in full canopied soybeans. Comparisons were made using Dropletscan™ software to calculate droplet statistics and deposition (percent area coverage) for both collector materials. Differences in coverage were found between products in all three collector positions in the canopy (top, middle, and bottom) with the top position being significant. Significant differences were found in the application volume and product comparisons for percent area coverage at all levels in the canopy. Typically the higher application volumes (28 L/ha) resulted in higher coverage's for all products tested. The combination treatment of Interlock and Preference resulted in the highest amount of coverage in the canopy. The presence of the soybean canopy reduced the amount of coverage in the top of the canopy nearly 3 times. Droplet size was slightly affected by the different tank mix products. The trend was for the higher application volume treatments to show increased droplet sizes.

Topic: Plant Surface Properties and Treatments
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
The utility of Foot Length as a Non-Invasive Anthropometric Measurement in Neonates Admitted in NICU in A Tertiary Care Centre in North Karnataka, India

Background: Most newborns in NICU would be on respiratory support either on invasive or non-invasive ventilation and it is difficult to measure anthropometries like weight, length and head circumference in these sick newborns. This study was aimed to determine the correlation of foot length of a newborn with occipitofrontal head circumference (OFC), crown-heel length (CHL) and weight of the newborn. Methods: A cross-sectional study was conducted in the NICU of Shri B M Patil Medical College Hospital and Research center, Vijayapura. The foot length, occipitofrontal head circumference (OFC) and crown-heel length (CHL) of neonates of gestational ages 28-42 weeks were measured between 12 hours and 7 days of life. Results: Among 350 neonates enrolled, 61% of babies were preterm and 39% were term babies. In premature babies, the correlation between foot length and birth weight (r=0.90) and foot length and length (r=0.89) was pronounced. A positive linear correlation was observed between foot length and weight in babies of all gestational ages. For the identification of LBW babies (<2500 gm), a foot length of less than 7.41cm had 94% sensitivity and 50% specificity. Foot length less than 6.62 cm had 100% sensitivity and 67% specificity for the identification of VLBW babies (<1500 gm). Conclusion: Birth weight and CHL of premature babies can be estimated from the measurement of foot length that was performed easily and rapidly. Measurement of foot length is valuable in premature babies on a ventilator. Foot length may be used in the identification of LBW and VLBW babies who are admitted to the NICU.

Topic: Neonatal Respiratory Health Research
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
[Spontaneous pneumopyelography: ureterocolic fistula caused by rectosigmoid carcinoma].

We present a case of ureterocolic fistula, secondary to a rectosigmoid carcinoma. The infrequency of these ureterocolic fistulae, contrasts with the more usual vesicointestinal ones. In our case, the diagnosis of pathological communication arose from the presence of gas in the excretory tract, after ruling out all those processes which could have led to a similar situation. In agreement with the world literature consulted, we confirm the great difficulty in tracing the course of the fistula by the usual means of diagnosis, in view of the minimal size of the pathological communication and the frequent obstructive behaviour of the fistula itself.

Topic: Infectious Disease Case Reports and Treatments
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Spray Dried Mucoadhesive Microspheres of Ondansetron for Nasal Administration

Systemic delivery of drugs via nasal route has many advantages for protein and peptide drug molecules as well as conventional molecules. Mucoadhesive drug delivery systems are those that provide intimate contact of the drug are those that provide intimate contact of the drug with the mucosa for an extended period of time. In this current work chitosan mucoadhesive microspheres of ondansetron HCL were prepared by spray-drying method, with an aim to avoid first pass effect and to improve therapeutic efficacy of Ondansetron in treatment of nauseas and vomiting. Preformulation studies were carried out in order to find out the drug excipient interaction in order to find out the drug excipients. I.R. spectrum and TLC method was used to find out the interaction between drug and excipient. Formulations were evaluated for physical characteristics such as particle size, incorporation efficiency, swelling ability in vitro bioadhesion and in vitro drug release in pH 6.6 phosphate buffer. Average particle size of microspheres was found to be in size of microspheres was found to be in size range 7-9 µm. All microspheres had good percentage of entrapment efficiency between 88% and 97% chitosan microspheres showed very good mucoadhesion due to electrostatic attraction between chitosan and mucin. The Fourier transformed infrared (FTIR) spectra obtained from various formulations of spray-dried microspheres showed no interaction within these formulations. The release of ondansetron hydrochloride from these microspheres was fast. These in vitro results show that spray-dried microspheres based on chitosan could be suitable nasal mucoadhesive delivery system for administration of ondansetron hydrochloride.

Topic: Advanced Drug Delivery Systems
Subfield: Pharmaceutical Science
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
Visit to Fernão Veloso, and Discovery and Survey of Nakala and Kisima Julu Bays – in 1881

O’Neill’s hitherto unpublished book makes available for the first time information on northern Mozambique in the late nineteenth century, on the slave trade and on the expansion of Portuguese rule and the resistance to it by powerful local communities.

Topic: Global Maritime and Colonial Histories
Subfield: Anthropology
Field: Social Sciences
Domain: Social Sciences
Mechanisms of antinatriuresis during low-frequency renal nerve stimulation in anesthetized dogs

The influence of 1.0 Hz renal nerve stimulation (RNS) on the renal excretion of sodium and bicarbonate was determined in anesthetized dogs before and during inhibition of renal bicarbonate reabsorption. RNS decreased both urinary sodium and bicarbonate excretion without changing arterial pressure, renal blood flow, or glomerular filtration rate. Pharmacological blockade of bicarbonate reabsorption with acetazolamide prevented RNS-induced decreases in bicarbonate excretion and reduced the antinatriuretic response. Physiological blockade of tubular bicarbonate reabsorption with intrarenal sodium bicarbonate infusion (1 M) abolished both the antinatriuretic response to RNS and the decrease in bicarbonate excretion. This physiological blockade of neurogenic antinatriuresis resulted from alkalinization of the urine and/or peritubular blood rather than an increase in filtered sodium load, because during intrarenal infusion of 1 M sodium chloride RNS concomitantly decreased sodium and urinary bicarbonate excretion. Since antinatriuretic responses and the decrease in bicarbonate excretion response to RNS were significantly decreased by blockade of bicarbonate reabsorption (with acetazolamide and intrarenal sodium bicarbonate infusion), antinatriuresis during RNS is partly mediated by a mechanism dependent on intact bicarbonate reabsorption. The data suggest that renal nerve activity may participate in the normal regulation of acid-base balance via changes in bicarbonate excretion.

Topic: Renal function and acid-base balance
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Cases of Extrauterine F tation, Detected at an Early Stage of Gestation

T-HE-,MIMZLS'ff MEDICAL _7URTAL.small to occlude; but then it should be recollected> -that-tiresvessels had been forcibly torn from the convolutions; and thwt;thelstr.iniexertedupon them, communicated to the fluid with which th-lWere distended, would be quite adequate to dislodge many of -them frdm the situations in which they had been impacted.It is, of course, obvious that such masses as those seen in Fig. i, if they had not previowsly been im- pacted in an artery, must have been on the very eve of being so at the time of the man's death.Vessels from all parts of the convolutional grey matter showed similar occluding masses within.An examination of portions of the liver showed the cells of the organ to be uniformly large and distended with granules.;whilst.hereand there were to be seen areas in which actual fatty degeneration had taken place.In the thin sections which were made, several of the hetic arteries were seen to contain masses of white blood-corpuscles-similr to those in the vessels of the brain; and a condition of thromboalvawa een in many of the portal veins; that is to say, in the sections of so-e'^these, there was seen within them (instead of the well-forned re blood-corpuscles, mixed with masses of white corpuscles, which were recognisable in others) only a dark reddish granular dibris, such as results from the breaking up of red blood-corpuscles, together with intermixed single and aggregated white blood-corpuscles.The kidneys presented appearances in every way analogous.Both -organs were extremely congested.The renal epithelium throughout was granular and swollen, so as almost completely to fill the tubules; and many of the vessels were blocked up with aggregated white cor- puscles, like those in the liver; whilst others showed evidences of a mere arrest of blood, and subsequent disintegration of red blood-cor--puscles.

Topic: Surgical Sutures and Adhesives
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Genome-wide DNA methylation analysis in Chinese Chenghua and Yorkshire pigs

Abstract Background The Chinese Chenghua pig (CHP) is a typical Chinese domestic fatty pig breed with superior meat quality characteristics, while the Yorkshire pig (YP) has the characteristics of fast growth and a high rate of lean meat. Long term natural selection and artificial selection resulted in great phenotypic differences between the two breeds, including growth, development, production performance, meat quality, and coat color. However, genome-wide DNA methylation differences between CHP and YP remain unclear. Results DNA methylation data were generated for muscle tissues of CHP and YP using reduced representation bisulfite sequencing (RRBS). In this study, a total of 2,416,211 CpG sites were identified. Besides, the genome-wide DNA methylation analysis revealed 722 differentially methylated regions (DMRs) and 466 differentially methylated genes (DMGs) in pairwise CHP vs. YP comparison. Six key genomic regions ( Sus scrofa chromosome (SSC)1:253.47–274.23 Mb, SSC6:148.71–169.49 Mb, SSC7:0.25–9.86 Mb, SSC12:43.06–61.49 Mb, SSC14:126.43–140.95 Mb, and SSC18:49.17–54.54 Mb) containing multiple DMRs were identified, and differences of methylation patterns in these regions may be related to phenotypic differences between CHP and YP. Based on the functional analysis of DMGs, 8 DMGs ( ADCY1 , AGBL4 , EXOC2 , FUBP3, PAPPA2 , PIK3R1 , MGMT and MYH8 ) were considered as important candidate genes associated with muscle development and meat quality traits in pigs. Conclusions This study explored the difference in meat quality between CHP and YP from the epigenetic point of view, which has important reference significance for the local pork industry and pork food processing.

Topic: Genetic and phenotypic traits in livestock
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
The Double Mutation DSG2-p.S363X and TBX20-p.D278X Is Associated with Left Ventricular Non-Compaction Cardiomyopathy: Case Report

Left ventricular non-compaction cardiomyopathy (LVNC) is a rare heart disease, with or without left ventricular dysfunction, which is characterized by a two-layer structure of the myocardium and an increased number of trabeculae. The study of familial forms of LVNC is helpful for risk prediction and genetic counseling of relatives. Here, we present a family consisting of three members with LVNC. Using a next-generation sequencing approach a combination of two (likely) pathogenic nonsense mutations DSG2-p.S363X and TBX20-p.D278X was identified in all three patients. TBX20 encodes the cardiac T-box transcription factor 20. DSG2 encodes desmoglein–2, which is part of the cardiac desmosomes and belongs to the cadherin family. Since the identified nonsense variant (DSG2-p.S363X) is localized in the extracellular domain of DSG2, we performed in vitro cell transfection experiments. These experiments revealed the absence of truncated DSG2 at the plasma membrane, supporting the pathogenic relevance of DSG2-p.S363X. In conclusion, we suggest that in the future, these findings might be helpful for genetic screening and counseling of patients with LVNC.

Topic: Cardiomyopathy and Myosin Studies
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Succession planning for the board

How do directors ensure that the succession planning for the board is optimised with respect to the long-term success of the organisation? Based on a framework of global corporate governance best practice, which can be used in all organisations anywhere in the world, this chapter of Questions To Ask (QTA) in the boardroom gives a high-level but succinct introduction to succession planning for the board. For many boards, succession planning is a reactive activity, triggered by the imminent departure of an existing member, usually through retirement or exhaustion of tenure. However, as many businesses seek to become more agile and find that the pace of change is accelerating, waiting for a board member to retire can result in stale boards which lack diversity of thought. The most efficient boards engage in a continual process of assessment and review to ensure their make-up is best suited to meet the upcoming strategic challenges of the business. The chapter’s introduction leads into the key Questions To Ask in the boardroom, giving the reader further insight into how to initiate discussions about the diversity of thought, effectiveness reviews, role specifications, and the recruitment Process.

Topic: Human Resource and Talent Management
Subfield: Organizational Behavior and Human Resource Management
Field: Business, Management and Accounting
Domain: Social Sciences
Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies

Typical crystallizable fragment (Fc) glycans attached to the CH2 domain in therapeutic monoclonal antibodies (mAbs) are core-fucosylated and asialo-biantennary complex-type glycans, e.g., G2F (full galactosylation), G1aF (terminal galactosylation on the Man α1-6 arm), G1bF (terminal galactosylation on the Man α1-3 arm), and G0F (non-galactosylation). Terminal galactose (Gal) residues of Fc-glycans are known to influence effector functions such as antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity (CDC), but the impact of the G1F isomers (G1aF and G1bF) on the effector functions has not been reported. Here, we prepared four types of glycoengineered anti-CD20 mAbs bearing homogeneous G2F, G1aF, G1bF, or G0F (G2F mAb, G1aF mAb, G1bF mAb, or G0F mAb, respectively), and evaluated their biological activities. Interestingly, G1aF mAb showed higher C1q- and FcγR-binding activities, CDC activity, and FcγR-activation property than G1bF mAb. The activities of G1aF mAb and G1bF mAb were at the same level as G2F mAb and G0F mAb, respectively. Hydrogen-deuterium exchange/mass spectrometry analysis of dynamic structures of mAbs revealed the greater involvement of the terminal Gal residue on the Man α1-6 arm in the structural stability of the CH2 domain. Considering that mAbs interact with FcγR and C1q via their hinge proximal region in the CH2 domain, the structural stabilization of the CH2 domain by the terminal Gal residue on the Man α1-6 arm of Fc-glycans may be important for the effector functions of mAbs. To our knowledge, this is the first report showing the impact of G1F isomers on the effector functions and dynamic structure of mAbs. <b>Abbreviations:</b> ABC, ammonium bicarbonate solution; ACN, acetonitrile; ADCC, antibody-dependent cell-mediated cytotoxicity; C1q, complement component 1q; CDC, complement-dependent cytotoxicity; CQA, critical quality attribute; Endo, endo-β-<i>N</i>-acetylglucosaminidase; FA, formic acid; Fc, crystallizable fragment; FcγR, Fcγ receptors; Fuc, fucose; Gal, galactose; GlcNAc, <i>N</i>-acetylglucosamine; GST, glutathione S-transferase; HER2, human epidermal growth factor receptor 2; HDX, hydrogen-deuterium exchange; HILIC, hydrophilic interaction liquid chromatography; HLB-SPE, hydrophilic-lipophilic balance-solid-phase extraction; HPLC, high-performance liquid chromatography; mAb, monoclonal antibody; Man, mannose; MS, mass spectrometry; PBS, phosphate-buffered saline; SGP, hen egg yolk sialylglycopeptides.

Topic: Monoclonal and Polyclonal Antibodies Research
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Liver damage in HIV-infected patients.

HCV and HBV co-infection is frequently encountered in this cohort of HIV-infected patients. In the majority of cases the liver diseases were asymptomatic or mildly symptomatic. The hepatic disorders found in HIV-infected patients are due to different etiopathogenic factors.

Topic: Liver Disease Diagnosis and Treatment
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Autobiography

Bertrand Russell remains one of the greatest philosophers and most complex and controversial figures of the twentieth century. Here, in this frank, humorous and decidedly charming autobiography, Russell offers readers the story of his life – introducing the people, events and influences that shaped the man he was to become. Originally published in three volumes in the late 1960s, Autobiography by Bertrand Russell is a revealing recollection of a truly extraordinary life written with the vivid freshness and clarity that has made Bertrand Russell’s writings so distinctively his own.

Topic: Philosophy, Science, and History
Subfield: History and Philosophy of Science
Field: Arts and Humanities
Domain: Social Sciences
Characterization of Adult Prostatic Progenitor/Stem Cells Exhibiting Self-Renewal and Multilineage Differentiation

Abstract Demonstration of the hallmarks of stem cells, self-renewal and multilineage differentiation, is a challenge that has not been met for numerous tissues postulated to possess adult stem cells, including prostate tissue. Using a defined medium, we reproducibly isolated and maintained adult mouse prostatic cells with characteristics of progenitor/stem cells. Clonal populations of cells demonstrated tissue-specific multilineage differentiation by their ability to generate organized prostatic ductal structures in vivo, with luminal and basal cell layers, when grafted under the renal capsules of mice in the presence of fetal rat urogenital mesenchyme. Complete differentiation was demonstrated by the expression and secretion of terminally differentiated prostatic secretory products into the lumens. Self-renewal was demonstrated by serial transplantation of clonal populations that generated fully differentiated ductal structures in vivo. In vitro, undifferentiated cells expressed markers associated with prostate stem cells, including Sca 1 and CD49f, as well as basal cell markers (p63 and cytokeratins 5 and 14) and, at a low level, luminal cell markers (androgen receptor and cytokeratins 8 and 18). When grafted and allowed to differentiate in the presence of fetal urogenital mesenchyme, the cells differentiated into luminal cells and basal cells with more restricted protein expression patterns. These studies are the first to report a reproducible system to assess adult prostatic progenitor/stem cells. Disclosure of potential conflicts of interest is found at the end of this article.

Topic: Tissue Engineering and Regenerative Medicine
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
3D Tissue Modeling of Skin Tissue

The skin is the largest organ of the body. As it is the first line of defense from the external environment, it is the most vulnerable organ to injury. In 2016, there were 500 000 burn patients, and they incurred astronomical medical costs. Researchers have studied a wide range of treatments for skin injuries, including wound dressing, skin tissue engineering, and cell sheets. However, there are limitations to these treatments. They cannot regenerate the full thickness of the skin or heal extensive burn wounds. Many researchers are working towards developing skin bioprinting, which is a promising technology that can potentially be applied to overcome the limitations of current burn treatments. One of the key advantages of this technology is that it can be used to produce biomimetic artificial skin with multiple types of skin cells. Hence, various studies have been conducted using bioprinting technology to generate advanced biomimetic and functional skins containing vasculature, pigmentation, sweat glands and hair follicles. The resulting skin substitutes are expected to have a range of applications including cosmetics, skin disease modeling and drug development. In this chapter, we will review progress in bioprinting technology relating to manufacturing artificial skins.

Topic: 3D Printing in Biomedical Research
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences