jimnoneill/paper-to-field-training huggingface dataset:
Tingkat Oksigen Dalam Darah Terhadap Kejadian Cardiac Arrest Pada Pasien Cidera Kepala Berat

The most common causes of severe head injuries are motor vehicle accidents and falls from a height that cause cardiac arrest. Cardiac arrest resulted in the patient being unconscious, no breathing, and no pulse. The incidence of cardiac arrest is mostly because the patient is hypoxic. Patients with severe head injuries are characterized by a Gasglow Coma Scale (GCS) of 8 or less. Patients with severe head injuries who often have decreased oxygen saturation should require a definitive airway to prevent patient death. This study aims to determine the level of oxygen in the blood on the incidence of cardiac arrest in patients with severe head injury. The research was conducted at Gambiran Hospital, Kediri City. Correlational research with cross sectional approaches. The sample of this research is 18 respondents. The sampling technique is total sampling. The statistical test of this research is Spearman's rho. The results of this study p value = 0.035 which means p &lt; (α = 0.05). There is a relationship between the level of oxygen in the blood and the incidence of cardiac arrest in patients with severe head injury.&#x0D; Keywords: Blood Oxygen Level, Cardiac arrest, Severe Head Injury.

Topic: Public Health and Nutrition
Subfield: Pediatrics, Perinatology and Child Health
Field: Medicine
Domain: Health Sciences
Soil penetration resistence in coffe plantations cultivated with mechanized and manual systems

Coffee harvesting mechanization systems reduce production costs, however, there is the chance of soil physical degradation due to considerable increase of machinery traffic. The objective of the present study was to evaluate the soil resistance to penetration in two coffee plantation systems and was developed in the municipality of Tres Corações – MG, in a farming divided in two turfs: one where all of the cultivation treatments were performed mechanically and one other turf where the treatments were performed manually. Measurements were performed with the help of a digital penetrometer in the cultivation line, traffic line and in the center of the cultivation leadings. The conclusion was that the mechanized cultivation system presents greater soil resistance values to penetration down to 0,15m depths and les humidity, when compared to the manual cultivation system.

Topic: Soil Management and Crop Yield
Subfield: Soil Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Ichthyofauna of the Reserva Biol&amp;oacute;gica Guaribas and surrounding areas, state of Para&amp;iacute;ba, Brazil

The removal and management of the Atlantic Forest over the past centuries caused the destruction of most of this ecosystem. Among the few remaining areas of Atlantic Forest north of the S&amp;atilde;o Francisco River is the Reserva Biol&amp;oacute;gica&amp;nbsp;(REBIO) Guaribas. This study inventoried the ichthyofauna of the REBIO Guaribas (Mamanguape, Para&amp;iacute;ba) and its&amp;nbsp;surroundings. Two streams were sampled bimonthly (1 within the REBIO and the other adjacent to it) and another 11&amp;nbsp;additional sites were sampled once, resulting in 18 species of fish (7 families and 7 orders). Characiformes was the&amp;nbsp;most representative order, with12 species. This species list is an important tool for impact assessments as well as conservation&amp;nbsp;and management plans, given the current state of knowledge about Brazilian rivers and streams, especially&amp;nbsp;those of the northeastern Atlantic Forest.

Topic: Fish biology, ecology, and behavior
Subfield: Nature and Landscape Conservation
Field: Environmental Science
Domain: Physical Sciences
Illness identity, experience, and perceptions as longitudinal predictors of adherence behaviors and health outcomes in adolescent Cystic Fibrosis

People with Cystic Fibrosis (CF) experience considerable symptom and treatment burden on a daily basis. Airway Clearance Therapy (ACT) is one of the most time-consuming treatments and has low rates of adherence. Adherence behaviors are important to address in adolescence, as patients begin to take over responsibility from parents. However, adolescents with CF experience unique barriers to treatment adherence. Their symptoms and treatments can disrupt developmentally-appropriate pursuits like peer relationships and affect identity development. Illness identity describes distinct ways in which chronic illness can be integrated into a patient’s identity, with varying effects on mental health and treatment adherence. Patients’ experience of CF also alters their treatment adherence by affecting beliefs about the necessity and efficacy of their treatments. As such, improving treatment adherence may require considering not only the adolescents’ illness- and treatment-related beliefs, but also the experiences that have informed those beliefs. This study of 120 adolescents with CF recruited from a Central Texas medical center uses regression to determine whether past illness-related health, represented by average pulmonary function, predicts ACT adherence, and whether illness identity and treatment beliefs (Beliefs) mediate the relationship. The study also uses regression to assess whether ACT adherence mediates the relationship between past Beliefs and future pulmonary function. This study would allow clinicians to identify adolescents with uncontrolled illness-related health as at higher risk for developing future maladaptive Beliefs that could affect treatment adherence. It would also provide guidance on targeted interventions for adolescents with chronically poor treatment adherence that take their unique developmental stage into account.

Topic: Cystic Fibrosis Research Advances
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Peroxisomes in <i>Saccharomyces cerevisiae:</i> Immunofluorescence Analysis and Import of Catalase A into Isolated Peroxisomes

To isolate peroxisomes from Saccharomyces cerevisiae of a quality sufficient for in vitro import studies, we optimized the conditions for cell growth and for cell fractionation. Stability of the isolated peroxisomes was monitored by catalase latency and sedimentability of marker enzymes. It was improved by (i) using cells that were shifted to oleic acid medium after growth to stationary phase in glucose precultures, (ii) shifting the pH from 7.2 to 6.0 during cell fractionation, and (iii) carrying out equilibrium density centrifugation with Nycodenz containing 0.25 M sucrose throughout the gradient. A concentrated peroxisomal fraction was used for in vitro import of catalase A. After 2 h of incubation, 62% of the catalase was associated with, and 16% was imported into, the organelle in a protease-resistant fashion. We introduced immunofluorescence microscopy for S. cerevisiae peroxisomes, using antibodies against thiolase, which allowed us to identify even the extremely small organelles in glucose-grown cells. Peroxisomes from media containing oleic acid were larger in size, were greater in number, and had a more intense fluorescence signal. The peroxisomes were located, sometimes in clusters, in the cell periphery, often immediately adjacent to the plasma membrane. Systematic immunofluorescence observations of glucose-grown S. cerevisiae demonstrated that all such cells contained at least one and usually several very small peroxisomes despite the glucose repression. This finding fits a central prediction of our model of peroxisome biogenesis: peroxisomes form by division of preexisting peroxisomes; therefore, every cell must have at least one peroxisome if additional organelles are to be induced in that cell.

Topic: Peroxisome Proliferator-Activated Receptors
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Reporting of Anticonvulsant Blood Levels

<h3>To the Editor.—</h3> The article by McDanal and Bolman (231:1063, 1975) presents a psychotic reaction to phenytoin (formerly diphenylhydantoin) that they conclude was an idiosyncratic reaction because blood levels of phenytoin were low. Unfortunately, there is as yet no generally agreed standard way of reporting anticonvulsant blood levels. Most laboratories report the levels as indicated by McDanal and Bolman in μg/mg, but others, including our own, continue to report the levels in mg/100 ml. This can lead to obvious confusion both on the part of the reporter as well as on the part of the reader. For example, the therapeutic range of phenytoin is indicated by the authors to be 10μg to 15μg/ml, which is the same as 1 to 1.5 mg/100 ml. Confusion in making this transposition led to erroneous statements, for example, in the 1969<i>Physician's Desk Reference</i>, concerning therapeutic and toxic levels of phenytoin, in which a

Topic: Pharmacological Effects and Toxicity Studies
Subfield: Pediatrics, Perinatology and Child Health
Field: Medicine
Domain: Health Sciences
Supplementary Table 7 from Glioblastoma-Specific Protein Interaction Network Identifies PP1A and CSK21 as Connecting Molecules between Cell Cycle–Associated Genes

Supplementary Table 7 from Glioblastoma-Specific Protein Interaction Network Identifies PP1A and CSK21 as Connecting Molecules between Cell Cycle–Associated Genes

Topic: Bioinformatics and Genomic Networks
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Far-infrared emission from Si-MOSFET’s on high-index surfaces

Voltage-tunable far-infrared emission was observed from n-channel Si-MOSFET’s on high-index surfaces. The emission results from radiative decay of electronic excitations across a minigap in the ground-state subband of the channel. We have observed emission of 10−9 W at 4.4 meV with a linewidth of ∼1 meV. Our results indicate that a voltage-tunable monochromatic source of several times 10−7 W and tuning from ∼1 to ∼20 meV is attainable.

Topic: Integrated Circuits and Semiconductor Failure Analysis
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
PLASMA-2013: International Conference on Research and Applications of Plasmas (Warsaw, Poland, 2–6 September 2013)

The PLASMA-2013 International Conference on Research and Applications of Plasmas was held in Warsaw (Poland) from 2 to 6 September 2013. The conference was organized by the Institute of Plasma Physics and Laser Microfusion, under the auspices of the Polish Physical Society. The scope of the PLASMA conferences, which have been organized every two years since 1993, covers almost all issues of plasma physics and fusion research as well as selected problems of plasma technology.

Topic: Laser-induced spectroscopy and plasma
Subfield: Mechanics of Materials
Field: Engineering
Domain: Physical Sciences
A novel approach to regulate cell membrane permeability for ATP and NADH formation in<i>Saccharomyces cerevisiae</i>induced by air cold plasma

Air cold plasma has been used as a novel method for enhancing microbial fermentation. The aim of this work was to explore the effect of plasma on membrane permeability and the formation of ATP and NADH in Saccharomyces cerevisiae, so as to provide valuable information for large-scale application of plasma in the fermentation industry. Suspensions of S. cerevisiae cells were exposed to air cold plasma for 0, 1, 2, 3, 4 and 5 min, and then subjected to various analyses prior to fermentation (0 h) and at the 9 and 21 h stages of fermentation. Compared with non-exposed cells, cells exposed to plasma for 1 min exhibited a marked increase in cytoplasmic free Ca2+ concentration as a result of the significant increase in membrane potential prior to fermentation. At the same time, the ATP level in the cell suspension decreased by about 40%, resulting in a reduction of about 60% in NADH prior to culturing. However, the levels of ATP and NADH in the culture at the 9 and 21 h fermentation stages were different from the level at 0 h. Taken together, the results indicated that exposure of S. cerevisiae to air cold plasma could increase its cytoplasmic free Ca2+ concentration by improving the cell membrane potential, consequently leading to changes in ATP and NADH levels.

Topic: Plasma Applications and Diagnostics
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Treatment of Left Main Coronary Artery Stenosis with Drug-Eluting Stent Following Heart Transplantation

Cardiac allograft vasculopathy is the leading cause of death after the first year of heart transplantation. The optimal treatment for unprotected left main coronary artery disease in orthotopic heart transplantation (OHT) patients is unknown. Two OHT patients with left main disease following heart transplantation underwent percutaneous coronary intervention (PCI). Technical success was achieved in the patients with drug-eluting stents inserted to cover the lesions in the left main coronary artery. After 16 months follow-up, one patient died of multiorgan failure, the other was alive and free from myocardial infarction or target vessel revascularization. We conclude that the unprotected PCI for the left main coronary artery stenosis in transplanted heart is feasible.

Topic: Transplantation: Methods and Outcomes
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Temporal changes in chromosome abnormality rate in human spontaneous abortions: evidence for an association between sex-chromosome monosomy and trisomy 16

As part of a cytogenetic survey of human spontaneous abortions, the relative frequencies of different categories of chromosome abnormalities were evaluated for possible temporal changes. Three classes of chromosome abnormalities showed significant linear trends; sex-chromosome monosomy and tetraploidy decreased over the study period, while trisomy increased. The increase in trisomy was largely attributable to trisomy 16, which showed a two-fold increase over the duration of the study. The linear increase in trisomy 16 was inversely related to sex-chromosome monosomy. This effect was restricted to women over 30 yr of age and was most pronounced among Oriental women.

Topic: Prenatal Screening and Diagnostics
Subfield: Pediatrics, Perinatology and Child Health
Field: Medicine
Domain: Health Sciences
The Boy's Forum: An Evaluation of a Brief Intervention to Empower Middle-School Urban Boys

Programs for middle-school boys are needed because data suggests that young adolescent males have problems as they grow and develop. Few gender role interventions for boys have been evaluated or published in the professional literature. Conceptual justification for boy's programs is given using psychosocial theory, gender role transitions, multicultural aspects of masculinity, and positive/healthy masculinity. A short term, inexpensive intervention, “The Boy's Forum,” was implemented for middle-school boys who were predominately Hispanic and African American. The Boy's Forum explained the hazards of growing up male (Goldberg, 1977) but also emphasized positive masculinity through empowerment, emotional awareness, and personal problem solving. The use of media, group discussions, empowerment themes, and adult self-disclosure to promote boy's psychosocial growth are described. Evaluation of the program occurred before the program, immediately after the program and three weeks later. Results indicate that a majority of boys attending the Boy's Forum reported that the programming positively affected their thinking, feelings, and to a lesser extent their behaviors over a three-week period. Limitations of the evaluation of this program, recommendations for future research, and the need for future curricular development for boys are discussed.

Topic: Gender Roles and Identity Studies
Subfield: Gender Studies
Field: Social Sciences
Domain: Social Sciences
Growth factor-dependent and independent regulation of skeletal muscle mass - Is IGF-1 necessary for skeletal muscle hypertrophy? -

Pituitary growth hormone (GH) and insulin-like growth factor-1 (IGF-1) play a critical role in the regulation of postnatal organ growth and overall body size. IGF-1 has been indicated as a very effective anabolic agent, and thus considered a critical regulator of skeletal muscle hypertrophy in response to increased workload such as resistance exercise. In contrast, recent studies using a genetic model of IGF-1/IGF-1 receptor have indicated that functional IGF-1-dependent mechanisms are not an absolute requirement for growth/hypertrophy in mature skeletal muscle. In this brief review, classic and recent aspects in hormonal/growth factor-dependent regulation of skeletal muscle mass are discussed. This review will particularly focus on 1) functional requirements of IGF-1 regulation in skeletal muscle hypertrophy and 2) cellular mechanisms in the regulation of protein synthesis in skeletal muscle.

Topic: Muscle Physiology and Disorders
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Polarimetric characterisation of histological section of skin with pathological changes

This work focuses on the further development of the optical methods based on polarization detection to improve the reliability of the results of evaluation of structural changes in biological tissues. The paper presents an experimental study of tissues with pathological alterations to assess the capacity of differentiation of pathological conditions when using averaged local Mueller matrix elements. Experiments were carried out in direct scattering mode in histological samples of human epidermis. The practical significance of the results is the widespread application of the methodology for laser polarimetric analysis of structural changes in anisotropic tissues to identify and assess the degree of pathology in medical diagnosis of skin diseases.

Topic: Advanced Scientific Research Methods
Subfield: Food Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Figure S3 from 27-Hydroxycholesterol Impairs Plasma Membrane Lipid Raft Signaling as Evidenced by Inhibition of IL6–JAK–STAT3 Signaling in Prostate Cancer Cells

&lt;p&gt;PC3 and DU145 dose finding studies for STAT3 inhibitors&lt;/p&gt;

Topic: Cancer, Lipids, and Metabolism
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Development and Evaluation of an In-House ELISA to Detect Anti-FcεR1α IgG Autoantibodies in Chronic Spontaneous Urticaria Patients

Background. Association between chronic spontaneous urticaria (CSU) and autoimmunity has been well documented. Autologous serum skin testing could support the autoimmune etiology of CSU, whereas it is difficult to interpret and could not be performed on antihistamine omitted patients. It was found that immunoglobulin G (IgG) autoantibodies (autoAbs) against high-affinity IgE receptor (FcεR1) were suggested as a potential trigger in the pathogenesis of CSU. Although many ELISA protocols have been developed to detect these autoAbs, they lacked validation or a reliable cut-off point. We, therefore, aimed to develop a validated ELISA with a reliable cut-off point to quantitate IgG anti-FcεR1α autoAbs for CSU. Methods. We developed an in-house ELISA to quantitate IgG anti-FcεR1α autoAbs. Sera from 233 CSU patients and 25 healthy people were used to test with ELISA. The cut-off point was obtained from the results subjected to analyze with receiver operating characteristic (ROC) analysis. ELISA was validated with 116 CSU patients and 150 healthy donors. Results. ELISA revealed that healthy people had a basal level of IgG anti-FcεR1α autoAbs, whereas their levels were significantly lower than autoAbs levels in CSU patients. ROC analysis of ELISA determined the cut-off point at 936.7 ng/ml. Our ELISA was validated and provided excellent sensitivity and specificity at 98.28% and 92.67%, respectively. Conclusion. Our ELISA could detect significant levels of IgG anti-FcεR1α autoAbs in CSU, supporting that these autoAbs were associated with CSU etiology. Our validated ELISA with the reliable cut-off point provided excellent accuracy at 95.11% (98.28% sensitivity and 92.67% specificity). Our ELISA could be an alternative test benefit for the patient who is unable to omit antihistamine treatment.

Topic: Urticaria and Related Conditions
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Various Constraints Perceived by Urd Growers in Southern Rajasthan

The present study was conducted in Banswara and Udaipur district of Southern Rajasthan. Total 80 urd beneficiary farmers were selected on the basis of random sampling method from the identified districts. The study revealed that timely non-availability of seed minikits of urd at village level, lack of skill about application of chemicals, improper knowledge about application of micro-nutrients, Non–availability of bio-fertilizers at village level, lack of technological guidance at proper time and inadequate knowledge about soil treatments were major constraints perceived by the beneficiary urd growers in the study area.

Topic: Agricultural Economics and Practices
Subfield: General Agricultural and Biological Sciences
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Dietary grape pomace mediates jejunum epithelial apoptosis through antioxidative activity in ram lambs

Wine grape pomace (WGP) contains polyphenols that possess antioxidative ability, and its potential as feed ingredients in the lamb industry remains undefined. The objective of this study was to investigate the effect of dietary WGP supplementation on jejunum epithelial morphology, apoptosis and antioxidative activity in lambs. A total of 18 lambs (25.0 ± 0.2 kg) were randomly selected and equally divided into three groups, and offered diet containing different levels of WGP (0%, 5% and 10%). The results showed that dietary WGP supplementation decreased reactive oxygen species concentration (p < .05). Supplementation with 10% dietary WGP reduced villus height (p < .05), while 5% WGP supplementation decreased crypt depth (p < .05), and increased villus height:crypt depth ratio (p < .05). Interestingly, apoptotic cell numbers were declined in WGP feeding lambs (p < .05). Supportively, 10% WGP supplementation decreased both phosphorylated ATM (p < .05) and Bax abundance (p < .05). Meanwhile, both 5% and 10% dietary WGP supplementation increased Bcl-2 abundance (p < .05) and reduced both active form of caspase 8 and caspase 9 protein levels (p < .05). As expected, the cleaved-caspase 3 content was reduced in WGP feeding lambs (p < .05). The total antioxidative capacity, catalase, glutathione peroxidase 4 and superoxide dismutase activity were increased when lambs were fed the WGP-containing diet (p < .05). Taken together, these results suggest that WGP can be used as a feed ingredient in lamb production to relieve jejunum epithelial apoptosis, possibly due to the enhanced of antioxidative capacity.Highlights Dietary wine grape pomace (WGP) supplementation alleviates ROS induced apoptosis and modifies the jejunum epithelium structure in ram lambs. WGP has great potential as a source of functional feed or additive in lamb industry.

Topic: Bee Products Chemical Analysis
Subfield: Insect Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences