jimnoneill/paper-to-field-training huggingface dataset:
Competition Climbing as Serious Leisure

Serious Leisure has received considerable attention in the leisure research for the past forty years. Building on recent efforts to operationalize serious leisure constructs, this study examined the relationship between serious leisure characteristics and rewards in the context of indoor competition climbing, a sport recognized as a potential serious leisure pursuit. The purposes of the study were to validate the 18-item Serious Leisure Inventory Measure (SLIM) as well as the three-factor model of serious leisure proposed by previous researchers. A national sample of 646 indoor competition climbers completed a 59-item survey. Results suggest partial validation of the 18-Item SLIM and a three factor model of serious leisure characteristics and rewards. Serious leisure characteristics significantly, positively contributed to personal and social rewards in the structural model, confirming the relationships and distinctions between these constructs. Further replication and validation of the 18-Item SLIM with different populations is recommended.

Topic: Recreation, Leisure, Wilderness Management
Subfield: Social Psychology
Field: Psychology
Domain: Social Sciences
The relationship between native English-speaking learners’ perception and lexical representation of Hindi affricates

Research often demonstrates discrepancies between learners’ perception and encoding of novel lexical contrasts. In some cases, L2 learners appear to establish contrastive lexical representations that are undermined by online perceptual neutralization (e.g., Cutler and Weber, 2006). In others, L2 learners’ target-like online perceptual representations access non-target-like lexical representations (e.g., Darcy et al., 2013). Here we further investigate the relationship between learners’ perceptual and lexical representation of novel contrasts in order to better understand the source of the difficulty that they face. Two groups of naive English speakers learned 5 minimal pairs distinguished by the notoriously difficult [tΠ]-[tʃʰ] aspiration or [tʃʰ]-[dʒh] voicing contrast among Hindi affricates. Following a word learning phase, participants were tested on their perception and lexical representation of the novel contrasts. We observed that while listeners generally demonstrated perceptual sensitivity to the two affricate contrasts, they failed to encode the novel contrast lexically. Interestingly, there was a significant positive correlation between participants’ perceptual acuity and their ability to contrast newly learned minimal pairs, suggesting that learner’s ability to encode a novel segmental contrast may be predicted by their pre-existing perceptual sensitivity, as has been reported for lexical tone contrasts (e.g., Perrachione et al., 2011).

Topic: Multisensory perception and integration
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
Nutritional supplementation of an apple callus extract to target epidermal aging

The global increase in life expectancy has led to a growing elderly population, which places a significant burden on healthcare systems. As a result, there is a growing interest to improve healthspan and promote healthy aging with accessible means, such as nutrition and lifestyle interventions. The skin, the body's largest organ and first line of defense against environmental stressors, is particularly vulnerable to aging due to both intrinsic and extrinsic factors. Various molecular and biochemical changes can drive skin aging, including the depletion of stem cells, which can lead to impaired skin properties. Nutrition plays a crucial role in skin aging, and dietary supplements could be a viable intervention to support a healthy skin. In this study, a plant callus extract from a specific apple variety (Malus Domestica Borkh), the Uttwiler Spätlauber, was evaluated as a dietary supplement to combat epidermal aging. The extract was found to maintain the function of keratinocyte progenitor cells during aging in vitro. Furthermore, an open-label pilot clinical study involving 31 female volunteers showed that the intake of apple callus extract led to improvements in skin elasticity, density, and firmness after 56 days of supplementation. This study highlights the potential of plant callus extracts as natural dietary supplements to support healthy skin aging. The use of plant callus cultures provides a sustainable and reproducible source of bioactive molecules, which is gaining acceptance in the nutraceutical market. These findings suggest that dietary interventions can play a role in promoting healthy skin aging and contribute to a holistic approach to improving healthspan during the aging process.

Topic: Plant tissue culture and regeneration
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Leveraging Comprehensive Cancer Registry Data to Enable a Broad Range of Research, Audit and Patient Support Activities

Traditional cancer registries have often been siloed efforts, established by single groups with limited objectives. There is the potential for registry data to support a broad range of research, audit and education initiatives. Here, we describe the establishment of a series of comprehensive cancer registries across the spectrum of common solid cancers. The experience and learnings of each registry team as they develop, implement and then use collected data for a range of purposes, that informs the conduct and output of other registries in a virtuous cycle. Each registry is multi-site, multi-disciplinary and aims to collect data of maximal interest and value to a broad range of enquiry, which would be accessible to any researcher with a high-quality proposal. Lessons learnt include the need for careful and continuous curation of data fields, with regular database updates, and the need for a continued focus on data quality. The registry data as a standalone resource has supported numerous projects, but linkage with external datasets with patients in common has enhanced the audit and research potential. Multiple projects have linked registry data with matched tissue specimens to support prognostic and predictive biomarker studies, both validation and discovery. Registry-based biomarker trials have been successfully supported, generating novel and practice-changing data. Registry-based clinical trials, particularly randomised studies exploring the optimal use of available therapy options are now complementing the research conducted in traditional clinical trials. More recent projects supported by the registries include health economic studies, personalised patient education material, and increased consumer engagement, including consumer entered data.

Topic: Cancer Genomics and Diagnostics
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
[Subunits of human holoenzyme of DNA dependent RNA polymerase III phosphorylated in vivo].

Phosphorylation of human holoenzyme of DNA dependent RNA polymerase III subunits in vivo has been investigated. RNA polymerase III from human placenta nuclei and epidermoid carcinoma cells A431 was isolated as two subfractions (IIIa and IIIb) distinguished in the order of elution from DEAE Sephadex A-25 column chromatography and buoyant density at glycerol gradient centrifugation. The subfractions of RNA polymerase III holoenzyme consists of four subunits with molecular masses 60, 52, 45 and 38 kDa, respectively, phosphorylated in vivo. The subunits with molecular masses 60 and 45 kDa are phosphorylated both on tyrosine and serine/threonine residues. All these subunits belong to subunits of the molecules of RNA polymerase III proper. RNA polymerase III and RNA polymerase I have the 38 kDa subunit in common. The subunit with molecular mass 52 kDa is phosphorylated on serine/threonine residues and may be related to some basal transcription factors of RNA polymerase III.

Topic: RNA and protein synthesis mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Qualitative and Quantitative Studies on DNA and RNA Synthesis in <i>Loxodes striatus</i> Nuclei*

SYNOPSIS. In this study the characteristics of the synthesis of DNA and RNA in the nuclei of Loxodes were investigated. Loxodes striatus is a primitive ciliate with 2 pairs of structurally differentiated diploid nuclei, the macro‐ and micronuclei. The macronuclei are differentiated morphologically into a clearly recognizable central core and an outer zone. To determine DNA and RNA synthesis, individual organisms were analyzed by autoradiography after incubating groups of cells with a 3 H‐labeled precursor ([ 3 H]thymidine for DNA and [ 3 H]uridine for RNA). The following observations were made: (A) All portions of macro‐ and micronuclei appeared to contain DNA as judged by the localizations of incorporated [ 3 H]thymidine. (B) The macro‐ and micronuclei did not synthesize DNA at the same time; moreover, the duration of DNA synthesis in the former was much longer than of the latter nucleus. (C) Replication of DNA in the inner core and outer zone of the macronucleus occurred at separate times with little if any overlap. (D) All of the detectable [ 3 H]uridine incorporation was found in the macronucleus and none in the micronucleus. Within the macro‐nucleus the central core was more heavily labeled. (E) The quantitative differences in the label of the different components of the nuclear complex were investigated. (F) Contrary to the previously reported information our results suggest that DNA synthesis can occur in adult macronuclei. The possible explanation of these results is discussed in the context of the nuclear evolution of ciliates and of recent information on nuclear differentiation.

Topic: Protist diversity and phylogeny
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Adaptive robust boundary control of coupled bending‐torsional vibration of beams with only one axis of symmetry

Summary In control design for vibration of beams in literature, the beam section is considered to have two axes of symmetry so that the bending and torsional vibrations are uncoupled; thus, the bending vibration is controlled independently without twisting the beam. However, if the cross section of a beam has only one axis of symmetry, the bending and torsional vibrations become coupled and the beam will undergo twisting in addition to bending. This paper addresses Lyapunov‐based boundary control of coupled bending‐torsional vibration of beams with only one axis of symmetry. The control strategy is based on applying a transverse force and a torque at the free end of the beam. The control design is directly based on the system partial differential equations (PDEs) so that spillover instabilities that are a result of model truncation are avoided. Three cases are investigated. Firstly, it is shown that when exogenous disturbances do not affect the beam, a linear boundary control law can exponentially stabilize the coupled bending‐torsional vibration. Secondly, a nonlinear robust boundary control is established that exponentially stabilizes the beam in the presence of boundary and spatially distributed disturbances. Thirdly, to rule out the need for prior knowledge of disturbances upper‐bound, the proposed robust control is redesigned to achieve an adaptive robust control that stabilizes the beam in the presence of disturbances with unknown upper‐bound. The efficacy of the proposed controls is illustrated by simulation results. Copyright © 2016 John Wiley &amp; Sons, Ltd.

Topic: Stability and Controllability of Differential Equations
Subfield: Control and Systems Engineering
Field: Engineering
Domain: Physical Sciences
Orange balsam (Impatiens capensis Meerb., Balsaminaceae): a re-evaluation by chromosome number and genome size<sup>1</sup>

Abstract Impatiens capensis Meerb. (1775) has been naturalized in the British Isles since the early 19th century. Though native to North America, the species is now established along waterways of lowland Britain and continues to increase its distribution across northern and central Europe. There have been two homonyms of I. capensis for a further two plant species with different sporophytic chromosome number. Impatiens capensis Thunb. (1794) is native to southern Africa, has a sporophytic chromosome number of 2n = 14, and now carries the accepted scientific species name I. duthieae L.Bolus (1921). Impatiens capensis Boj. ex Baker (1883) is native to Madagascar, has a sporophytic chromosome number of 2n = 14, and now carries the accepted scientific species name I. firmula Baker (1883). Karyological analyses of plants from three geographically separated I. capensis Meerb. populations from the River Thames Valley proved the sporophytic chromosome number of 2n = 20 and estimated the mean sporophytic unreplicated nuclear DNA amount of 2C ≌ 1.55 pg, which corresponds to a genome size of approximately 1.51264 Gbp per nucleus.

Topic: Plant Diversity and Evolution
Subfield: Ecology, Evolution, Behavior and Systematics
Field: Agricultural and Biological Sciences
Domain: Life Sciences
[LDL-cholesterol-lowering effect of a mixed green vegetable and fruit beverage containing broccoli and cabbage in hypercholesterolemic subjects].

The serum LDL-cholesterol (LDL-C)-lowering effects of two types of canned beverage containing mixed green vegetables and fruits, with or without broccoli and cabbage (B&C), were examined in a randomized double-blind study design. Seventy-seven adults subjects with mild to moderate hypercholesterolemia participated in this study after giving their informed consent. The subjects were randomly divided into two groups. One group(test group) was allocated a test sample, containing B&C as the main materials. Another group(control group) was allocated a placebo sample made from the same materials but without B&C. The subjects were administered 2 cans of the assigned sample (160 g contents/can) per day for 12 weeks. Forty-nine out of 77 subjects, whose LDL-C levels were greater than or equal to 140 mg/dl and less than 180 mg/dl, were analyzed for the effectiveness. Serum LDL-C levels in the test group were significantly(p < 0.05) reduced at 3, 6 and 9 weeks after administration in comparison to the baseline levels (155.7 mg/dl in average). The average LDL-C value at 9 weeks was 142.5 mg/dl and the reduction rate was 8.5%. But serum LDL-C levels in the control group were not significantly reduced. Significant differences(p < 0.05) between the groups were observed in the LDL-C levels at 6 and 9 weeks and also in the total cholesterol levels at 9 week. Thus daily intake of the beverage tested containing B&C are useful for lowering serum LDL-C levels in hypercholesterolemic subjects.

Topic: Nutrition, Genetics, and Disease
Subfield: Genetics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Battery Power Saving Profile with Learning Engine in android Phones

Android is an open platform which is becoming very popular operating system.Its open source code is easily handled by the users to get and use new contents and applications on their handsets.Android is based on Linux kernel.Android device are being activated per day and power management of these device is becoming an issue.The one problem is common that is Low battery life of the device.It is not a common thing in smartphones.Now days, more powerful with power consuming technologies like GPS, 3G and 3GS.In this approach we do not require the client server architecture .wewill include a learning engine.This learning will monitor the user behavior in terms of apps used, battery consumption and contexts, and then we will collect the information for a period of time and the fed to a learning engine.Artificial neural can be used to implement the learning engine.This pattern based learning engine intelligently decide, how to control the smartphones features.This will build after the learning of user behavior, would not include any statically define power saving profile.

Topic: Green IT and Sustainability
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
[Prehospital management of febrile convulsions by the Mobile Emergency Care Unit in the Capital Region of Denmark].

In general, parents appreciate the service provided by the MECU. Reasons of dissatisfaction are described. On several occasions, the prehospital physician administered intravenous anticonvulsants, but we discuss if the MECU should still be dispatched primarily to febrile convulsions.

Topic: Emergency and Acute Care Studies
Subfield: Emergency Medicine
Field: Medicine
Domain: Health Sciences
Episode 8: Leanne Schinkel

In episode, I chat with University of Regina alum and documentary filmmaker Leanne Schinkel about her film The Last Steamship, documentary filmmaking, types of docs and individual films, the state of SCN, the vague dissappointment over Cave of Forgotten Dreams, sailing and the days of the film program.

Topic: Magnetic confinement fusion research
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
Supplementary Figure 13 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers

Supplementary Figure 13 from MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers

Topic: MicroRNA in disease regulation
Subfield: Cancer Research
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
NASSP's National Study of Leadership in Middle Level Schools: Understanding Leaders and Programs in Highly Successful Middle Level Schools

Files attached below (in order) are "Leadership for Highly Successful Middle Level Schools" (part 1), "NASSP's National Study of Highly Successful Middle Level Schools and Their Leaders: Selected Comparisons of Leaders in Middle Level Schools Programs and Practices" (part 2), "Cornerstones On Which Programs and Practices were Built and Sustained" (part 3), and "Leadership in Six Highly Successful Middle Level Schools" (part 4).

Topic: Diverse Educational Innovations Studies
Subfield: General Agricultural and Biological Sciences
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Communication: Teaching an Elusive Discipline

De Wet, J.C. 1988. The Art of Persuasive Communication. Communicamus Series 1. Johannesburg: Juta. Pp. iii-94. Fourie, P.J. 1989. Aspects of Film and Television Communication. Communicamus Series 2. Johannesburg: Juta. Pp. xi-112. Jansen, N. 1989. Philosophy of Mass Communication Research. Communicamus Series 3. Johannesburg: Juta. Pp. x-111. Du Plooy, G.M. 1989. Understanding Television - Guidelines for Visual Literacy. Communicamss Series 4. Johannesburg: Juta. Pp. ix-102. Oosthuizen, L.M. 1989. Media Policy and Ethics. Communicamus Series 5. Johannesburg: Juta. Pp. ix-102. De Wet, J.C., R.S. Rensburg. 1989. Evaluation of Public Speaking. Communicamus Series 6. Johannesburg: Juta. Pp. viii-113.

Topic: Communication in Education and Healthcare
Subfield: Social Psychology
Field: Psychology
Domain: Social Sciences
Business Management Concept Evaluation in the Context of Public Relationship

Public relations in a strategic sense are addressed in three dimensions : in the order , at the level of functionality strategy , and at the level of operations . at the level of social strategy , public relations is a process that focuses on social relations , establishes a balance between business aims and social responsibility , and emphasizes a sustainability target audience and stakeholder connection _ Corporate governance , a strategic communication strategy based on mutually beneficial relationships between corporations and society , is commonly consider as a function of public relations _ Of this study , general information regarding " business management " and " public relations " functions is provided , along with exhaustive explanations and an analysis of their interrelationships .

Topic: Public Relations and Crisis Communication
Subfield: Communication
Field: Social Sciences
Domain: Social Sciences
Modeling client/server interactions by means of dynamic systems

The dynamic evolution of ecological systems in which predators and prey compete for survival has been investigated by applying suitable mathematical models. This kind of mathematical framework has been shown to be suited to describe evolution of economical systems as well, where instead of predators and prey there are consumers and resources. We believe that this kind of system, called dynamic systems, could be usefully applied to informatics context, for example to model the dynamic interactions of client/server systems, such as Internet users and Web servers. We present the general mathematical model, often referred to in biological and economics literature, and show how to apply dynamic systems theory to model client/server interactions in different system load conditions. Web clients compete to obtain some URLs from the server and the efficiency of the server decreases when the number of clients increases, in a similar way to predator and prey populations. The feasibility of this approach is supported by experimental results.

Topic: Game Theory and Applications
Subfield: Management Science and Operations Research
Field: Decision Sciences
Domain: Social Sciences
Chromosome-Level Genome Assembly and Comparative Genomic Analysis of the Barbel Chub (Squaliobarbus curriculus) by Integration of PacBio Sequencing and Hi-C Technology

The barbel chub (Squaliobarbus curriculus), the only species in the genus, is widely distributed in freshwater lakes and rivers at different latitudes in East Asia, with fishery and biodiversity importance, and is an emerging commercially important fish in China. However, the resource of this species has dramatically declined due to anthropogenic activities such as over-exploitation, as well as water pollution. Genomic resources for S. curriculus are useful for the management and sustainable utilization of this important fish species, and also for a better understanding of its genetic variation in the region. Here, we report the chromosome-level assembly of the S. curriculus genome obtained from the integration of PacBio long sequencing and Hi-C technology. A total of 155.34 Gb high-quality PacBio sequences were generated, and the preliminary genome assembly was 894.95 Mb in size with a contig N50 being 20.34 Mb. By using Hi-C data, 99.42% of the assembled sequences were anchored to 24 pseudochromosomes, with chromosome lengths ranging from 27.22 to 58.75 Mb. A total of 25,779 protein-coding genes were predicted, 94.70% of which were functionally annotated. Moreover, S. curriculus shows resistance to grass carp haemorrhagic disease (GCHD) caused by grass carp reovirus (GCRV), which seriously hinders the status and future perspectives of commercial grass carp production. Phylogenetic analysis indicated that S. curriculus diverged with grass carp (Ctenopharyngodon idellus) approximately 20.80 million years ago. Annotations of the expanded gene families were found to be largely enriched in immune-related KEGG pathway categories. Moreover, a total of 18 Toll-like receptor (TLR) genes were identified from the whole genome of S. curriculus. The high-quality genome assembled in this study will provide a valuable resource for accelerating ecological, evolutionary, and genetic research on S. curriculus.

Topic: Genomics and Phylogenetic Studies
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences