Adult Group B Streptococcal Disease

Letters15 July 1996Adult Group B Streptococcal DiseaseDouglas C. Waite, MD, Eric J. Alper, MD, and Brian J. Mady, MDDouglas C. Waite, MDUniversity of Massachusetts Medical Center, Worcester, MA 01605Search for more papers by this author, Eric J. Alper, MDUniversity of Massachusetts Medical Center, Worcester, MA 01605Search for more papers by this author, and Brian J. Mady, MDUniversity of Massachusetts Medical Center, Worcester, MA 01605Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-125-2-199607150-00018 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Group B streptococci account for less than 1% of organisms causing meningitis in adults and are seen in immunocompromised and immunocompetent hosts [1]. Persons infected with the human immunodeficiency virus (HIV) have a risk for invasive group B streptococcal infection 30 times greater than that seen in persons without HIV infection [2]. We report the first case of group B streptococcal meningitis in a patient with HIV infection who had had splenectomy.A 39-year-old HIV-positive man with a CD4 count of 1100 cells/mm3 who had had splenectomy 10 years earlier presented with a 2-day history of fever ...References1. Dunne DW, Quagliarello V. Group B streptococcal meningitis in adults. Medicine (Baltimore). 1993; 72:1-10. Google Scholar2. Farley MM, Harvey RC, Stull T, Smith JD, Schuchat A, Wenger JD, et al. A population-based assessment of invasive disease due to group B streptococcus in nonpregnant adults. N Engl J Med. 1993; 328:1807-11. Google Scholar3. Hill HR. Group B streptococcal infections. In: Holmes KK, Mardh P, Sparling PF, Wiesner PJ, Cates W Jr, Lemon SM, et al, eds. Sexually Transmitted Diseases. 2d ed. New York: McGraw-Hill; 1990:854-5. Google Scholar4. Tremlett CH, Ridgway EJ, Allen KD. Fatal group B streptococcal septicaemia 16 years after splenectomy. J Infect. 1993; 28:107-8. Google Scholar5. Jackson LA, Hilsdon R, Farley MM, Harrison LH, Reingold AL, Plikaytis BD, et al. Risk factors for group B streptococcal disease in adults. Ann Intern Med. 1995; 123:415-20. Google Scholar Author, Article, and Disclosure InformationAffiliations: University of Massachusetts Medical Center, Worcester, MA 01605 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInfluence of proteins Bsp and FemH on cell shape and peptidoglycan composition in group B streptococcus c cThe GenBank accession number for the sequence reported in this paper is AJ305309.Identification and Molecular Analysis of PcsB, a Protein Required for Cell Wall Separation of Group B StreptococcusOverwhelming Postsplenectomy Infection Caused by Group B Streptococcus: A Case Report and Review of the LiteratureSurvival of Group B Streptococcus Type III in Mononuclear Phagocytes: Differential Regulation of Bacterial Killing in Cord Macrophages by Human Recombinant Gamma Interferon and Granulocyte-Macrophage Colony-Stimulating Factor 15 July 1996Volume 125, Issue 2Page: 152KeywordsCerebrospinal fluidGroup A streptococcal infectionHIV infectionsKneesMeningitisNeutrophilsPenicillinSplenectomyStreptococcal infectionsSynovial fluid Issue Published: 15 July 1996 Copyright & PermissionsCopyright © 1996 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

Topic: Neonatal and Maternal Infections
Subfield: Public Health, Environmental and Occupational Health
Field: Medicine
Domain: Health Sciences