jimnoneill/paper-to-field-training huggingface dataset:
Reply to Terzi et al.

We read with interest the paper by Bai et al. [1] regarding the efficacy of surgery, mainly pneumonectomies, in the treatment of tuberculosis (TB)-destroyed lungs and we congratulate them on their results.One of the most dreaded complications after pneumonectomy is the bronchopleural fistula (BPF), and this is particularly true for pneumonectomies performed for infectious diseases including TB.The authors report a very low incidence of BPF, but they do not give information about the method, if any, they use to reinforce the bronchial stump.It should be of great interest to know whether or not they protect the stump and to know which criteria they use to decide who can benefit from the bronchial stump coverage.For Wang et al.[2], the incidence of BPF was 9% when parietal pleura or the pericardium were used to protect the bronchial stump, and it was as high as 36% when they were not.According to Pomerantz [3], positive sputum at the time of surgery and polymicrobial contamination increases the risk of BPF, and he suggests using muscle flaps to protect the bronchial stump.In our experience, we used with satisfaction a muscle flap of the serratus anterior or a split latissimus dorsi flap [4] in all sputum-positive patients, most of whom also had a polymicrobial contamination of the destroyed lung.Both these flaps can be easily and quickly harvested and add only a minimal morbidity to the operation.

Topic: Pleural and Pulmonary Diseases
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
MRSA Defenses Found

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal

Topic: Antimicrobial Resistance in Staphylococcus
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Red‐Shifted Bioluminescence Using Substrate‐Fluorophore Conjugates

Abstract NanoLuc (NLuc) is one of the brightest luciferases and has been used in numerous reporter assays and sensor designs. However, its blue light emission (460 nm) is suboptimal for deep tissue imaging or some diagnostic application, and red shifting its emission is desirable. Here, we report the design and synthesis of novel furimazine and coelenterazine analogs conjugated with fluorophores to achieve red‐shifted bioluminescence with NLuc and closely related H‐Luc via a bioluminescence resonance energy transfer (BRET). Structural insights into NLuc‐substrate interactions informed the functionalization of substrates. We report the synthesis of novel substrate‐fluorophore conjugates. We show that red‐shifted emission was achieved with high BRET ratios. The conjugates are less bright than the parent substrates, but our study highlights the importance of linker length and flexibility for optimizing bioluminescence emission reaching wavelength beyond 600 nm.

Topic: bioluminescence and chemiluminescence research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Gait classification of stroke survivors - An analytical study

Gait of post-stroke patients have been analyzed and classified in this paper. Data pertaining to gait of both post-stroke patients and healthy people of the same age group were obtained and analyzed. Xsens motion capture system was used for obtaining this data from 40 people belonging to both categories. Advanced modern machine learning techniques such as Logistic Regression, Multilayer Perceptron (MLP), Support Vector Machine (SVM), and Extreme Gradient Boosting (XGBoost) were employed for classifying the data obtained. Accurate spatiotemporal parameters values for gait were obtained. Amongst the different machine learning techniques, XGBoost gave the most accurate classification result of about 96%. The walking patterns of the patients who had undergone a stroke attack were analyzed. severity of abnormal gait patterns was a key factor that was taken into consideration and points were given accordingly. The data presented in this paper can be used to develop diagnostic tools for gait rehabilitation of stroke survivors, to evaluate and estimate their way of walking in order to understand their progress. It can be used to understand the different types of walking disorders post-stroke and thereafter select the right kind of treatment that needs to be implemented for proper recovery.

Topic: Stroke Rehabilitation and Recovery
Subfield: Rehabilitation
Field: Medicine
Domain: Health Sciences
Menstrual Cycle Changes in Mate Preferences for Cues Associated with Genetic Quality: The Moderating Role of Mate Value

The purpose of the study was to explore the influence of mate value and fertility status on women's implicit and explicit preferences for male traits associated with genetic quality. It was hypothesized that a woman low in mate value would experience greater fluctuation across her menstrual cycle in her preferences for characteristics associated with genetic quality than a woman high in mate value. Specifically, a low mate value woman during the non-fertile part of the cycle would experience a reduction in a desire for traits associated with health and reproductive success. To test the hypothesis, the college age female participants completed two measures of mate value and a self-report measure designed to gauge fertility status. Then the participants performed an Implicit Associations Test (IAT) designed to measure implicit associations with a male trait related to genetic quality and a questionnaire designed to measure their explicit responses to the same trait. As predicted, mate value moderated the relationship between fertility status and implicit preferences.

Topic: Evolutionary Psychology and Human Behavior
Subfield: Experimental and Cognitive Psychology
Field: Psychology
Domain: Social Sciences
A 17ns 64K CMOS RAM with a schmitt trigger sense amplifier

This paper will describe a CMOS SRAM using a four-transistor cross-coupled flip-flop memory cell with a high resistivity load composed of the second poly-Si. Cell is 12.5μm <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">× 21.5μ</tex> m. Die is 3.86mm×6.99mm that can De packaged in a 300 mil wide 22 pin plastic DIP.

Topic: Low-power high-performance VLSI design
Subfield: Electrical and Electronic Engineering
Field: Engineering
Domain: Physical Sciences
Platelet Indices Are Associated with Disease Activity Scores and the Severity of Sacroiliitis on Magnetic Resonance Imaging in Axial Spondyloarthritis Patients

Objective To investigate the associations among platelet indices, disease activity scores, and inflammatory markers in axial spondyloarthritis, and to determine the relation between platelet indices and inflammation measured on magnetic resonance imaging (MRI). Methods The study included 161 patients who fulfilled Assessment of Spondyloarthritis International Society criteria. Platelet indices such as mean platelet volume (MPV), plateletcrit (PCT), platelet large cell ratio (PLCR), and platelet distribution width (PDW) were measured. Ninety patients underwent sacroiliac (SI) MRI at baseline. Bone marrow edema (BME) and erosion on MRI were scored using the SPondyloArthritis Research Consortium of Canada (SPARCC) method. Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Ankylosing Spondylitis Disease Activity Score (ASDAS) and spinal radiologic progression were also assessed. The associations among platelet indices and disease activity scores and inflammatory markers were evaluated. Results Of the 161 patients, 130 (81%) were male. MPV, PLCR, and PDW were negatively associated with ASDAS and inflammatory marker expression, whereas PCT was positively associated with these parameters. MPV, PLCR, and PDW were negatively associated with BME and erosion scores on SI MRI. However, platelet indices were not associated with the BASDAI and BASFI. The mean erythrocyte sedimentation rate, C-reactive protein, and BME and erosion scores were significantly higher in patients with low MPV. Changes in MPV, PCT, and PDW at baseline and after one year were associated with changes in ASDAS and inflammatory marker expression. Conclusion Platelet indices are associated with ASDAS, inflammatory marker levels, and severity of BME and erosion measured on MRI.

Topic: Spondyloarthritis Studies and Treatments
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Biological activity of polysaccharides from the mycelial culture of Tylopilus felleus (Bull.: Fr.) P. Karst.

Polysaccharide A and B fractions from mycelial culture of Tylopilus felleus (Bull,: Fr.) P. Karst. were isolated. The acidic hydrolysis of the polysaccharides yielded glucose and peptidic part. Both polysaccharide fractions revealed mitodepressive and mitostatic activities in Allium test.

Topic: Cancer Treatment and Pharmacology
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Association between early parental deprivation and cellular immune function among adults in rural Fujian, China

Abstract This study investigated the role of childhood parental deprivation in the association between quality of life (QOL) and the Epstein–Barr virus (EBV) antibody titer, a marker of cellular immune functioning, using data from 734 adults living in seven communities in rural Fujian, China. Parental deprivation was defined if either of their parents had died, divorced, or left them for migratory work for more than 1 year before they turned (a) 16 years of age (childhood and adolescence), or (b) 3 years of age (early childhood). A mixed‐effects regression analysis with a random effects model revealed that parental deprivation during early childhood was positively associated with the EBV antibody titer (coefficient = 0.33, p = 0.007), whereas parental deprivation during the first 16 years was not. Further analysis incorporating an interaction term between QOL and parental deprivation revealed a significant interaction between QOL and parental deprivation during early childhood; a significant association between QOL and the EBV antibody titer was found only among those who reported parental deprivation during early childhood. This study suggests that parental deprivation during the period of immune system development may be linked with physiological responses to stressors later in life.

Topic: Early Childhood Education and Development
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Ecocide in the Amazon: the contested politics of environmental rights in Brazil

Though a discussion of the 2019 Brazilian Amazon fires, this article examines the contested politics of environmental rights in Brazil. It analyses how the concept of ecocide can offer a useful lens with which to articulate the socio-ecological consequences of President Bolsonaro’s extractive imperialism, and the persistent failure of current international governance frameworks to address the continuing widespread destruction of the natural environment. Firstly, the article places the concept of ecocide within the context of the international governance framework of the 2030 Agenda for Sustainable Development and the challenges that natural resource exploitation presents to the achievement of sustainable development in Latin America. Secondly, it presents an overview of the concept of ecocide that includes cultural genocide as a method for undermining a way of life and a technique for group destruction. Lastly, through an analysis of Brazil’s environmental politics, contested claims of sovereignty and the recent push for the industrialisation of the Amazon, the article considers whether claims of ecocide in the Brazilian Amazon can be substantiated when using the criteria for the crime of ecocide–namely the size, duration and impact of the extensive damage to, destruction of or loss of ecosystems in the Amazon rainforest.

Topic: Wildlife Conservation and Criminology Analyses
Subfield: Nature and Landscape Conservation
Field: Environmental Science
Domain: Physical Sciences
An implantable window system for chronic two-photon microscopy on mouse organs

Animal models were developed for chronic observation with using two-photon microscopy. To demonstrate potency of the models, T-cell and macrophage migration in inguinal lymph node, spleen, abdominal cavity and kidney were observed for two weeks on single mice. The image quality was maintained high enough during an observation period to count and trace cell population and migration.

Topic: Advanced Fluorescence Microscopy Techniques
Subfield: Biophysics
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Formation of vocal-stage mastery of the future singer-novice on vocal lessons

The purpose of the theses is to highlight the important pedagogical conditions and stages of the student's preparation for public speaking in vocal classes, which will promote the consistent and systematic pedagogical activity of the teacher to the formation of vocal-stage mastery in the future of the beginner singer.

Topic: Environmental Engineering and Cultural Studies
Subfield: Information Systems
Field: Computer Science
Domain: Physical Sciences
[A case of mediastinal cavernous hemangioma].

A case of mediastinal cavernous hemangioma was reported. An asymptomatic 6-year-old girl was discovered to have a mass in the left anterior superior mediastinum on a routine chest x-ray film. Computed tomograms demonstrated a mediastinal mass with calcification. Under a median sternotomy, a 10 x 9 x 5 cm mass was resected after dissecting the connections to the pericardium. As the mass surrounded the left phrenic nerve, the nerve was resected with the tumor. The histopathology was cavernous hemangioma. The calcification was not found in the vessels as the phleboliths but was showed in the interstitial tissues.

Topic: Vascular Malformations and Hemangiomas
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Sedative polypharmacy mediates the effect of mechanical ventilation on delirium in critically ill <scp>COVID</scp>‐19 patients: A retrospective cohort study

Abstract Background Polypharmacy of sedatives (PP) is a potentially modifiable, iatrogenic risk factor for ICU delirium. The extent to which sedative PP influenced development of high rates of delirium among critically ill COVID‐19 patients is unknown. We tested the hypothesis that PP, defined as the use of four or more classes of intravenous agents, is a mediator in the causal pathway of mechanical ventilation and delirium. Methods Retrospective cohort study of adults admitted with a primary diagnosis of RT‐PCR+ for SARS‐CoV2 to ICUs of a tertiary‐level academic medical center between February 2020 and April 2021. Mediation analysis was conducted with bootstrap estimation to assess whether an association between mechanical ventilation and delirium was mediated by PP. Analyses were adjusted for potential confounders related to mechanical ventilation, mediator, and outcome, including age, gender, vasopressor use, median RASS scores, SOFA score within 24 h of admission, and maximum CRP levels. Results A total of 212 patients were included in the analysis. Of total patients, 72.6%(154/212) of patients had delirium (CAM‐ICU+) during ICU stay. 54.7%(116/212) patients received PP. Mechanical ventilation (OR 3.81 [1.16–12.52]) and PP (OR 7.38 [2.4–22.68]) were identified as risk factors for development of ICU delirium after adjusting for prespecified confounders. PP acts as a mediator in the causal pathway between mechanical ventilation and delirium. 39% (95% CI: 17%–94%) of the effect of mechanical ventilation on delirium was mediated through PP. Conclusion PP mediates approximately 39% of the effect of mechanical ventilation on delirium, which is clinically and statistically significant. Studies should assess whether mitigating PP could lead to reduction in ICU delirium. Implication Statement PP of sedatives (defined as use of four or more intravenous agents) mediates approximately 39% of the effect of mechanical ventilation on development of ICU delirium. Avoidance of sedative PP may represent a viable strategy for reduction of ICU delirium.

Topic: Intensive Care Unit Cognitive Disorders
Subfield: Critical Care and Intensive Care Medicine
Field: Medicine
Domain: Health Sciences
Fascism in Popular Memory: The Cultural Experience of the Turin Working Class

Preface Introduction Part I. Oral Sources and the analysis of Cultural Identities: 1. Memories of self- autobiography and self-representation Part II. Oral Sources and the History of Grass-Roots Cultural Forms: 2. Fascism and the symbolic order in everyday life Part III. Oral Sources and the History of the events of Everyday Life: 3. Forms of social acceptance of Fascism 4. Resistance to demographic policy 5. Mussolini's visit to Mirafiori Appendix Notes Index.

Topic: Italian Fascism and Post-war Society
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Floral evolution in the Ranunculaceae

Six clearly separable evolutionary levels in the floral evolution of the Ranunculaceae were found to coincide with the six corresponding stages of sensory development of their pollinators as follows: amorphic -> haplomorphic -> actinomorphic -> pleomorphic -> stereomorphic-zygomorphic. This is a basic trend of floral evolution, fully recapitulated in a single family. Except for the first (amorphic), all upper levels are represented in the present-day floras as clearly separable type-classes. They are therefore accessible to direct observations and experimental study. Extensive statistical data on flower visitors of the Ranunculaceae confirm the proposed theory of the mutual interrelationship between the evolutionary levels of flower types and sensory stages of pollinating insects. The new picture, obtained by this study, gives us a better understanding of the evolutionary relationship between insects and plants and explains the extreme diversity in the floral structure of the Ranunculaceae.

Topic: Hermeneutics and Narrative Identity
Subfield: Philosophy
Field: Arts and Humanities
Domain: Social Sciences
Stability of Shells Attached to Elastic Core

The effect upon the buckling strength of a soft elastic core attached to a shell of revolution subjected to axisymmetric loads is investigated. The axisymmetric stress problem is solved by using the finite element method to solve the body of revolution problem with an axis of material symmetry subjected to Fourier expandable thermal, body force, and surface traction loading. The governing equations are derived for a triangular toroidal continuum element attached to shell elements. The elastic core influence coefficient matrix of the core is derived by applying the unit line load at the interface nodal point of the core. The inversion of the influence coefficient matrix yields an equivalent stiffness matrix of the core which is then combined with the shell stiffness matrix. Results from this investigation are in good agreement with available analytical and experimental results for cylindrical shells. New results are obtained for conical and spherical shells.

Topic: Composite Structure Analysis and Optimization
Subfield: Mechanics of Materials
Field: Engineering
Domain: Physical Sciences
STATISTICAL TOLERANCE TRANSFER FOR COMPLEX SHEET METAL PART FORMING

Current process planning practice and theory for sheet metal part forming does not consider transfer of geometric tolerances (GD&T). To eliminate this shortcoming, GD&T tolerance transfer is implemented using a statistical model of machining errors and a Monte-Carlo simulation. Considered sources of errors comprise positioning errors of the part and bend lines, bending angles, and blanking. Typical sheet metal parts are studied.

Topic: Manufacturing Process and Optimization
Subfield: Industrial and Manufacturing Engineering
Field: Engineering
Domain: Physical Sciences
Breathing Capacity and Grip Strength of Preschool Children.

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Pediatrics HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Pediatrics journal

Topic: Child and Adolescent Health
Subfield: General Health Professions
Field: Health Professions
Domain: Health Sciences
Conformation characters of gel sheets with rotational symmetry: the role of boundary

In this paper, we systemically study the conformation characters of rotational symmetric gel sheets with free boundary and investigate the role of boundary on the equilibrium conformation. In gel sheet the boundary provides a residual strain which leads to re-distribution of stress and impacts the shape of equilibrium conformation accordingly. For sheet with boundary, the in-plane stretching energy is far larger than the bending energy in some cases. It is intrinsic different from closed membrane. In gel sheets, the boundary doesn't only quantitatively amend to the elastic energy. The residual strain on boundary cooperates with bending and stretching to determine the equilibrium conformation rather than just the last two factors. Furthermore, on the boundary of gel sheet, there is an additional energy induced by boundary line tension $γ$. If $γ=0$, there is $10\%$ difference of elastic energy from the experimental result. Finally, we discuss the effects of such line tension $γ$ and propose a way to measure it by the border radius. It redounds to study the physical origination of $γ$.

Topic: Advanced Materials and Mechanics
Subfield: Mechanical Engineering
Field: Engineering
Domain: Physical Sciences