jimnoneill/paper-to-field-training huggingface dataset:
Minimum viable governance for data science initiatives

Too much governance can stifle innovation in organizations. Too little governance can waste precious organizational resources. Business agility demands empowerment of people to take decisions on initiatives designed to deliver innovative products and services. Traditional monthly and quarterly governance forums such as steering committees and program boards for decision-making potentially impede the flow of work when the delivery of a program or project is done using agile methods in two-weekly sprints. Data science initiatives (DSIs), which are exploratory and innovative in nature, follow agile delivery methods and often require decisions in a different and more frequent cadence. This chapter is an exploratory study of implementing governance for DSIs based on a single case study at Transport for New South Wales. It investigates agile governance at project, program, and portfolio level for DSIs and suggests eight guiding principles focusing on product and portfolio governance. It is targeted at practitioners to guide them in setting minimum viable governance to ensure value is realized from their DSIs and for academics to advance research in governance of DSIs.

Topic: Qualitative Comparative Analysis Research
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Supplementary Table S1. Association between raw garlic consumption and lung cancer stratified by major risk factors among men and women from Raw Garlic Consumption and Lung Cancer in a Chinese Population

&lt;p&gt;This supplementary table presents the results of association between raw garlic consumption and lung cancer stratified by major risk factors among male and female participants.&lt;/p&gt;

Topic: Garlic and Onion Studies
Subfield: Plant Science
Field: Agricultural and Biological Sciences
Domain: Life Sciences
Assessing the Effect of a Continuous Evaluation Strategy on the Success of an Undergraduate Course on Particle Technology

Particulate Technology is a horizontal subject that traverses several scientific and technological fields. In fact, when speaking about Particle Technology we are referring to both phenomena and processes involved in disperse systems: powders, droplets, emulsions, aerosols, etc, that are present in a large variety of industrial and economic activities. Thus, particulate technology, although many times associated with Chemical Engineering, is relevant to many other engineering and scientific fields. Particulate Technology has been receiving an increasing attention both from the education and research angles, especially in Europe, having evolved from what was considered as an art, to a structured scientific field. In t he Chemical Engineering curriculum of the University of Coimbra, Particle Technology has acquired since soon (1988) an autonomous status. It is possible to confi rm that the competencies acquired in that field, by our chemical engineering graduates, constitute an added value for their employability. Many companies have become aware of the importance of a deeper understanding of particulate processes and this has contributed to reinforce the partnership university/industry. This paper explains the strategy adopted to teach Particulate Technology at the University of Coimbra, focusing on the benefits for the employability of the graduates. The paper gives also notice of a continuous evaluation strategy which has contribu ted to an increase of success rate and average marks.

Topic: Science, Technology, and Education in Latin America
Subfield: Demography
Field: Social Sciences
Domain: Social Sciences
134: USE OF THROMBOELASTOGRAPHY FOR MONITORING HEPARIN IN EXTRACORPOREAL MEMBRANE OXYGENATION THERAPY

Wallskog, Kirsten; Feih, Joel; Rinka, Joseph; Tawil, Justin; Gaglianello, Nunzio; Kruetziger, Lisa Baumann; Joyce, David Author Information

Topic: Thermal Regulation in Medicine
Subfield: Critical Care and Intensive Care Medicine
Field: Medicine
Domain: Health Sciences
Intermediality: Disciplinary flux or formalist retrenchment?

Click to increase image sizeClick to decrease image size Notes 1. F. Senn, ‘Reading Ulysses’, radio series of 20 episodes (2004). Episode 8: ‘Lestrygonians’. RTÉ Radio 1, Dublin, produced by Ann Marie O’Callaghan. 2. One impulse for this special issue is the very slim number of Anglophone contributions to the intermediality debate. For example, only one of the nine texts cited as examples by Livia Monnet in her 2002 Monnet, L. 2002. Towards the feminine sublime, or the story of ‘a twinkling monad, shape‐shifting across dimension’: Intermediality, fantasy, and special effects in cyberpunk film and animation. Japan Forum, 14(2): 225–68. [Taylor & Francis Online] , [Google Scholar] list of five definitions of intermediality is written in English (six are in French and one is in German) (2002, 229–30). This issue therefore takes the opportunity to bring recent work carried out by two of the term’s Francophone proponents into English in the form of André Gaudreault and Philippe Marion’s ‘The mysterious affair of styles in the age of kine‐attractography’.

Topic: European Cultural and National Identity
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
512 Systemic Norepinephrine Impact on Tangential Split Thickness Skin Graft Outcomes in Burn Shock Patients

Abstract Introduction Blood pressure supporting agents like vasopressors are often used to treat patients with burn shock. Norepinephrine is part of the algorithms used by regional burn centers for fluid resuscitation in burn shock. In our population of burn shock patients, we have noticed an association of poor graft take when norepinephrine is used. We undertook this study to assess the relationship between systemic norepinephrine use and split-thickness skin graft (STSG) healing. Methods We retrospectively identified burn patients who presented to our burn center from January 2014 –June 2020, who were treated with systemic vasopressors within the first 48 hours of admission, and received at least one tangential excision and STSG procedure as part of their treatment. We compared these patients to a matched control group of burn patients who did not receive vasopressors for resuscitative purposes. The primary outcome investigated was graft take percentage at time of graft takedown. Results During the time frame, we found 19 patients and 19 matched controls within the same time period who did not receive norepinephrine. The mean percent graft take for patients treated with systemic norepinephrine was 77.9% (SE = 3.00), which was significantly lower than that of the control group, 92.8% (SE = 3.56) (P= &amp;lt; 0.001). Furthermore, patients who received norepinephrine had a statistically significant increase in both hospital (P= 0.038) and intensive care unit (ICU) length of stay (P= 0.009). The two populations were equivalent in all other characteristics such as TBSA, number of comorbidities, age, and resuscitation volumes. Conclusions In this retrospective assessment, the use of norepinephrine seems to have a significant association with worse graft take and longer length of stay. Since graft loss begets more graft reoperations and a longer stay, our findings would lead one to incorporate norepinephrine as a last resort in the treatment algorithm for burn shock.

Topic: Wound Healing and Treatments
Subfield: Rehabilitation
Field: Medicine
Domain: Health Sciences
Spinning dilaton black hole in 2 + 1 dimensions as a particle accelerator

In this paper, we have studied particle collision around a spinning dilaton black hole in 2 + 1 dimensions. This black hole is a solution to the low-energy string theory in 2 + 1 dimensions. Time-like geodesics are presented in detail and the center-of-mass (CM) energy of two-particle collision at the horizon of a spinning black hole is considered. We noticed that there is a possibility of the two masses to create infinite CM energy.

Topic: Black Holes and Theoretical Physics
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
Site-specific mutations alter in vitro factor binding and change promoter expression pattern in transgenic plants.

The 35S promoter of cauliflower mosaic virus (CaMV) is able to confer high-level gene expression in most organs of transgenic plants. A cellular factor from pea and tobacco leaf tissue, which recognizes nucleotides in a tandemly repeated TGACG motif at the -75 region of this promoter, has been detected by DNase I footprinting and gel retardation assays. This factor is named activation sequence factor 1 (ASF-1). A cellular factor binding to the two TGACG motifs can also be detected in tobacco root extracts. Mutations at these motifs inhibit binding of ASF-1 to the 35S promoter in vitro. When examined in transgenic tobacco, these mutations cause a 50% drop in leaf expression of the 35S promoter. In addition, these same mutations attenuate stem and root expression of the 35S promoter about 5- to 10-fold when compared to the level of expression in leaf. In contrast, mutations at two adjacent CCAAT-box-like sequences have no dramatic effect on promoter activity in vivo. A 21-base-pair element containing the two TGACG motifs is sufficient for binding of ASF-1 in vitro when inserted in a green-tissue-specific promoter. In vivo, the insertion of an ASF-1 binding site caused high levels of expression in root. Thus, a single factor binding site that is defined by site-specific mutations is shown to be sufficient to alter the expression pattern of promoters in vivo.

Topic: Transgenic Plants and Applications
Subfield: Biotechnology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Rodzaje aukcji na wytwarzanie energii elektrycznej z odnawialnych źródeł energii w świetle przepisów ustawy o odnawialnych źródłach energii

After an analysis of certain legal texts, the authors have established that under Polish law the President of the Energy Regulatory Offi ce may conduct 56 diff erent types of auctions for generators of the electric energy from renewable sources (RSE). For each individual RSE installation complying with the RES parameters a separate auction may be carried. One RSE installation may take part in several RSE auctions provided it satisﬁ es the parameters of each individual installation. These parameters concern both the premises connected with the start-up process (the commencement of the production of electric energy) of a given installation and the premises of technical nature such as carbon dioxide emission or the level of the installation capacity used, as well as premises of a subjective character regarding individual producers participating in the auction. A detailed analysis of all types of RSE auctions described in the Act of 20 February 2015 on renewable sources of energy allows to determine which types of installation may take part in individual actions. However, of key importance from the point of view of the possibility of a RSE auction to be carried are secondary regulations which allow the Council of Ministers to determine individual types of RSE auctions in which the volume of energy, subject of the auction, will be made available. Consequently the Council of Ministers which runs the State policy within the area of RSE has become essentially responsible not only for the possibility of conducting an RSE auction, but also for the implementation of the EU climate and energy policy which is also binding upon Poland.

Topic: Renewable energy and sustainable power systems
Subfield: Renewable Energy, Sustainability and the Environment
Field: Energy
Domain: Physical Sciences
SOM-Based Clustering of Multilingual Documents Using an Ontology

Clustering similar documents is a difficult task for text data mining. Difficulties stem especially from the way documents are translated into numerical vectors. In this paper, we will present a method which uses Self Organizing Map (SOM) to cluster medical documents. The originality of the method is that it does not rely on the words shared by documents but rather on concepts taken from an ontology. Our goal is to cluster various medical documents in thematically consistent groups (e.g. grouping all the documents related to cardiovascular diseases). Before applying the SOM algorithm, documents have to go through several pre-processing steps. First, textual data have to be extracted from the documents, which can be either in the PDF or HTML format. Documents are then indexed, using two kinds of indexing units: stems and concepts. After indexing, documents can be numerically represented by vectors whose dimensions correspond to indexing units. These vectors store the weight of the indexing unit within the document they represent. They are given as inputs to a SOM which arranges the corresponding documents on a two-dimensional map. We have compared the results for two indexing schemes: stem-based indexing and conceptual indexing. We will show that using an ontology for document clustering has several advantages. It is possible to cluster documents written in several languages since concepts are language-independent. This is especially helpful in the medical domain where research articles are written in different languages. Another advantage is that the use of concepts helps reduce the size of the vectors, which, in turn, reduces processing time.Request access from your librarian to read this chapter's full text.

Topic: Semantic Web and Ontologies
Subfield: Artificial Intelligence
Field: Computer Science
Domain: Physical Sciences
Was It a Profitable Business?

This penultimate chapter attempts to answer whether or not merchant shipping in the seventeenth and eighteenth centuries was a profitable enterprise. It first quantifies the costs of operating ships, including wages, earnings, and profit, by analysing the account books of shipmasters and various other contemporary sources. It divides running costs into four sections: wages and crew costs; repairs and stores; port charges, pilotage and lighthouse dues; and miscellaneous expenses; and explores each in turn. After determining the cost of operations and of ships themselves, it then considers capital charge rates per annum. It asserts that voyage estimates alone cannot determine the profitability of shipping, and so turns to examine rates of financial ruin; increases in flow of capital into the industry; and the nature of fluctuating returns inherent to long-distance shipping. It concludes that these factors caused profit to vary, but stresses that it was not merely financial gain that led people to a career at sea, but an affection for ships and the appetite for adventure as much as enterprise, which renders financial gain less imperative.

Topic: Historical Economic and Social Studies
Subfield: Economics and Econometrics
Field: Economics, Econometrics and Finance
Domain: Social Sciences
Incidence, mortality and risk factors of drug-induced acute kidney injury: A multi-center study in China

Objective: The aim of this study was to investigate the incidence, prognosis and risk factors of the prognosis of drug-induced acute kidney injury (AKI) in hospitalized patients in 23 third-level urban hospitals in China.

Topic: Drug-Induced Hepatotoxicity and Protection
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
A Life Saving Exchange: A Case of Severe Direct Hyperbilirubinemia And Liver Failure in Leptospirosis Successfully Treated with Plasma Exchange

Leptospirosis is an infection with multiorgan involvement and a high mortality rate. Extreme hyperbilirubinemia in leptospirosis has been reported to exert multiple cellular toxic effects on kidney and liver cells. We describe a young man with leptospirosis who had extreme hyperbilirubinemia, acute liver injury, coagulopathy, hepatic encephalopathy, and pulmonary haemorrhages. Early initiation of therapeutic plasma exchange (PEX) dramatically improved patient’s clinical and biochemical parameters. We conclude that, in addition to the mortality benefit provided by PEX in severe pulmonary hemorrhage syndrome in leptospirosis, PEX is also beneficial in reducing systemic toxic insults of hyperbilirubinemia.

Topic: Leptospirosis research and findings
Subfield: Parasitology
Field: Immunology and Microbiology
Domain: Life Sciences
Innovating Emergency Medicine: Generative AI, Narrative Medicine, and Human-Centered Design

Background: Emergency medicine in resource-limited settings faces a growing burden of disease and disability. This article presents the "Create to Innovate" (C2i) masterclass, built using Human-Centered Design Thinking (HCDT). It explores narrative medicine through AI-generated storytelling. The study aimed to assess (1) how generative AI contributes to emergency medicine innovation and (2) its impact on participants' emotional engagement. Methods: The C2i masterclasses were held in Karachi, Pakistan (December 2023) and Lagos, Nigeria (March 2024). This study used an explanatory mixed-methods approach, collecting quantitative data from a post-intervention 'MoodBoard' survey and qualitative data from AI-generated children's stories. The total sample size was 60 participants. The quantitative data was analyzed using descriptive statistics and a two-sample t-test comparing responses between the Karachi and Lagos cohorts. Results: The study included 22 participants in Karachi and 38 in Lagos. The MoodBoard visual analog scale revealed a significant difference in the mean scores between the two cohorts (Karachi: 3.74 vs. Lagos: 3.96, p &lt; 0.05, CI: -0.42 to -0.01). The AI-generated stories revealed themes of prosocial behavior, resourcefulness, and health awareness. Conclusion: The masterclass achieved its goal of fostering innovative solutions through storytelling. The MoodBoard survey highlighted its effectiveness and enjoyment. The imaginative stories offered educational insights into healthcare challenges, highlighting their potential for broader applications in healthcare education and professional training.

Topic: Empathy and Medical Education
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
[RE: Getty Center's National Conference, October 5, 1992]

Photocopy of a letter from Vicki Rosenberg, program officer of the Getty Center, to the Regional Institute Directors. Providing logistics about the Center's Fourth National Conference, "Achieving National Education Reform: Arts Education As Catalyst." The letter in an invitation to attend the conference, to be held February 4 - 6, 1992 at the San Francisco Hilton and Towers. The next two pages are a letter from Julie Able, from the office of Rosenberg, to the Regional and Californian Institute Directors, providing information on expected arrival schedules, purchasing airfare, and details exhibition booth spaces and where to ship their materials prior to the conference date.

Topic: Art Education and Development
Subfield: Visual Arts and Performing Arts
Field: Arts and Humanities
Domain: Social Sciences
Intraoperative autotransfusion for elective aortic surgery

Abstract Intraoperative autotransfusion using the Bentley ATS 100 was used in 23 patients requiring Dacron replacement of their abdominal aorta. An average of 2000 ml of blood was reinfused and a total heparinization dose was given. The mean haemoglobin fell 2·8 g/dl and on average 2 pints of banked blood were given in the post-operative period. Coagulation studies performed before and after surgery showed minimal alteration. We feel that further evaluation of this system is essential so that an alternative is established for when banked blood is not available. The system is particularly useful at the present time for such emergencies as a leaking abdominal aortic aneurysm and severe trauma to the live.

Topic: Trauma, Hemostasis, Coagulopathy, Resuscitation
Subfield: Critical Care and Intensive Care Medicine
Field: Medicine
Domain: Health Sciences
PET molecular imaging of fibroblast activity after myocardial infarction using a 68Ga-labelled fibroblast activation protein inhibitor (FAPI-04)

Myocardial infarction (MI) and subsequent heart failure (HF) is associated with significant morbidity and mortality worldwide. Spatial and temporal presence of the activated fibroblasts in the injured myocardium predicts the quality of cardiac remodeling post-MI. Therefore, monitoring of activated fibroblasts is of great interest for studying myocardial remodelling after MI. Fibroblast activation protein (FAP) expression is upregulated in activated fibroblasts. This study sought to investigate the potential of a 68Ga-labelled FAP inhibitor (68Ga-FAPI-04) for PET imaging of activated fibroblasts in a preclinical model of MI.

Topic: Peptidase Inhibition and Analysis
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
DNA Methylation at Specific Loci is Associated with Overall Survival in The Cancer Genome Atlas Patients

DNA methylation influences gene expression and is altered in many cancers, but the relationship between DNA methylation and cancer outcomes is not yet fully understood. To advance our understanding of DNA methylation in cancer biology, we studied the relationship between methylation and cancer outcomes across 28 different cancer types. Using data from The Cancer Genome Atlas (TCGA), we used Cox proportional hazards regression to establish associations between methylation of individual genes and overall survival of patients in 28 studies, each examining a different cancer type. Our results showed that the numbers of genes with significant associations varied widely across studies, yet some of the genes recurred across many cancer types. The genes that recurred across cancer types were enriched for certain biological functions, including immunity and cell‐cell adhesion. There were similar numbers of genes for which methylation was associated with better survival and genes for which methylation was associated with worse survival. While these recurrent genes appeared across the entire genome, they were enriched in certain genomic regions. We also used RNA sequencing data to learn about possible mechanisms to explain the association between DNA methylation and survival. As expected, higher methylation of genes associated with survival was frequently accompanied by reduced mRNA levels. Increased methylation of genes that suppress tumor growth could contribute to worse outcomes, and increased methylation of genes that promote tumor growth could contribute to better outcomes. Ultimately, while global DNA methylation is known to be associated with outcome in certain cancers (such as prostate cancer and colorectal cancer), our results suggest that DNA methylation at specific loci also plays a role. Our work suggests that understanding patterns of localized DNA methylation is important for optimal development and use of cancer treatments.

Topic: Epigenetics and DNA Methylation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
IMPROVING FINGER FORCE CONTROLWITH VIBRATIONAL HAPTIC FEEDBACK FORMULTIPLE SCLEROSIS

Pathologies including stroke and multiple sclerosis can leave patients with impaired tactile and proprioceptive sen-sation, which contributes to their difficulty in performing everyday tasks. We present the results that indicate that a combination of fingertip force sensing and vibrational feedback can help patients with multiple sclerosis improve their performance in manipulation tasks. The feedback can take the form of an “event cue ” in which patients are alerted when forces at the fingertips stray outside of a rec-ommended range, or proportional feedback, in which trains of vibration pulses are correlated directly with the fingertip forces. While both types of feedback allow the patients to handle objects with more accurate force control, the for-mer approach is more successful and preferred by subjects with mild impairment while the latter approach appears to be most effective for patients with severe impairment.

Topic: Motor Control and Adaptation
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences