jimnoneill/paper-to-field-training huggingface dataset:
Acute Myocardial Infarction Due to Spontaneous Coronary Artery Dissection – A Series of Five Cases

We report a series of five patients hospitalized due to acute coronary syndrome, from 2008 to 2010, in whom coronary angiography showed spontaneous coronary dissection. Spontaneous coronary artery dissection is a rare cause of acute myocardial infarction, most commonly seen in young individuals with no history of cardiovascular disease. The optimal management is uncertain, especially due to the limited clinical experience with this entity. Intravascular ultrasound is a useful tool to diagnose spontaneous coronary artery dissection as well as to guide percutaneous therapy. Infarto Agudo do Miocárdio por Dissecção Espontânea de Artérias Coronárias – Série de Cinco Casos Relatamos série de 5 pacientes internados por síndrome coronária aguda, entre 2008 e 2010, nos quais a cinecoronariografia evidenciou dissecção coronária espontânea. A dissecção coronária espontânea é uma causa rara de infarto do miocárdio, mais comumente observada em indivíduos jovens e sem histórico de doenças cardiovasculares. O manejo ideal é incerto, principalmente pela limitada experiência clínica com essa entidade. A ultrassonografia intracoronária é uma ferramenta útil tanto para o diagnóstico da dissecção coronária espontânea como para guiar o tratamento percutâneo.

Topic: Cardiovascular Issues in Pregnancy
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Body mass index, perceived and actual physical competence: the relationship among young children

Abstract Background The purpose of this study was to examine the relationship between perceived physical competence ( PPC ), actual motor competence ( MC ) and body mass index ( BMI ) in young children. Methods We assessed MC ( T est of G ross M otor D evelopment – 2nd Edition), PPC (Pictorial Scale of Perceived Competence and Social Acceptance) and BMI ( CDC calculator) of 178 young children ages 4–7 years. Results The linear regression model for the overall sample showed that BMI was a better predictor of PPC than MC . Also, obese children had lower PPC , but showed no differences in MC compared with leaner peers. Conclusions PPC of young obese children was lower than their leaner counterparts, yet their MC was similar. That outcome draws attention to the importance of promoting positive PPC in young children.

Topic: Children's Physical and Motor Development
Subfield: Developmental and Educational Psychology
Field: Psychology
Domain: Social Sciences
VALUE APPROACH TO THE EVALUATION OF MANAGERS’ WORK EFFECTIVENESS

The problem of evaluation of the effectiveness and quality of work of managers arises from the fact that the owners community of the Russian business starts to feel ready for the transfer of management functions to employees. These trends are complicated by many reasons, among of which we should highlight the lack of objective methods of evaluation of managers’ work effectiveness. At the same time, there are rather reliable methods of evaluation in foreign practice, based on the objective financial data. In this regard, there is a need to adapt the tools and methods to the activities of Russian enterprises developed by foreign scientists and used by practices. And as is the customary in modern management, the main purpose of management of the company is the increase of its value and, as a result, the shareholders' welfare, calculation of the cost is becoming one of the main tools for the evaluation of the quality and efficiency of the managers’ work. In this paper, the technique of using one of the methods is given, which is based on the determination of the intrinsic cost of the business with the purpose of business management and control over the activity of managers

Topic: Economic Development and Regional Competitiveness
Subfield: Economics and Econometrics
Field: Economics, Econometrics and Finance
Domain: Social Sciences
RETRACTED: Analysis and prediction of β-turn types using multinomial logistic regression and artificial neural network

Abstract Motivation So far various statistical and machine learning techniques applied for prediction of β-turns. The majority of these techniques have been only focused on the prediction of β-turn location in proteins. We developed a hybrid approach for analysis and prediction of different types of β-turn. Results A two-stage hybrid model developed to predict the β-turn types I, II, IV and VIII. Multinomial logistic regression was initially used for the first time to select significant parameters in prediction of β-turn types using a self-consistency test procedure. The extracted parameters were consisted of 80 amino acid positional occurrences and 20 amino acid percentages in β-turn sequence. The most significant parameters were then selected using multinomial logistic regression model. Among these, the occurrences of glutamine, histidine, glutamic acid and arginine, respectively, in positions i, i+1, i+2 and i+3 of β-turn sequence had an overall relationship with 5 β-turn types. A neural network model was then constructed and fed by the parameters selected by multinomial logistic regression to build a hybrid predictor. The networks have been trained and tested on a non-homologous dataset of 565 protein chains by nine fold cross-validation. It has been observed that the hybrid model gives a Matthews correlation coefficient (MCC) of 0.473 and 0.124, respectively, for β-turn types II and VIII which are best among previously reported results. Our model also distinguished the different types of β-turn in the embedded binary logit comparisons which have not carried out so far. Availability Available on request from the authors.

Topic: Protein Structure and Dynamics
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Formation control of autonomous robots to track a moving target in an unknown environment

This paper presents a novel approach to path planning for the formation of a swarm of autonomous robots to track a moving target in an unknown environment. This approach is based on the traditional potential fields combined with the rotational vector field. The potential field is used to repel the robots away from obstacles while the rotational vector field is added to drive robots to avoid obstacles in the direction of the target's trajectory. Under the effect of the blended vector field, autonomous robots can easily escape obstacles in order to quickly reach the target. In this approach, the neighboring robots in a swarm will be linked to each other by the attractive and the repulsive vector field between them in order to generate a stable formation. Moreover, information about obstacles, which each member robot detects from the environment, will be sent to all other member robots in the swarm. Hence, the formation of the swarm is maintained while tracking a moving target. The effectiveness of this proposed approach has been verified in simulations.

Topic: Robotic Path Planning Algorithms
Subfield: Computer Vision and Pattern Recognition
Field: Computer Science
Domain: Physical Sciences
Phenomenological Aspects of Supersymmetric Gauge Theories

In this thesis we study two important phenomenological issues in the context of supersymmetric gauge theories. In the Minimal Supersymmetric Standard Model (MSSM) we analyze properties of the neutral Higgs boson decays into two neutralinos. In the second part of our work we study in detail the Proton decay in the Minimal Supersymmetric SU(5) Theory.

Topic: Black Holes and Theoretical Physics
Subfield: Nuclear and High Energy Physics
Field: Physics and Astronomy
Domain: Physical Sciences
Neurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling

Abstract Introduction Giant cell arteritis (GCA) is characterized by intimal hyperplasia leading to ischaemic manifestations that involve large vessels. Neurotrophins (NTs) and their receptors (NTRs) are protein factors for growth, differentiation and survival of neurons. They are also involved in the migration of vascular smooth muscle cells (VSMCs). Our aim was to investigate whether NTs and NTRs are involved in vascular remodelling of GCA. Methods We included consecutive patients who underwent a temporal artery biopsy for suspected GCA. We developed an enzymatic digestion method to obtain VSMCs from smooth muscle cells in GCA patients and controls. Neurotrophin protein and gene expression and functional assays were studied from these VSMCs. Neurotrophin expression was also analysed by immunohistochemistry in GCA patients and controls. Results Whereas temporal arteries of both GCA patients ( n = 22) and controls ( n = 21) expressed nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), tropomyosin receptor kinase B (TrkB) and sortilin, immunostaining was more intense in GCA patients, especially in the media and intima, while neurotrophin-3 (NT-3) and P75 receptor (P75 NTR ) were only detected in TA from GCA patients. Expression of TrkB, a BDNF receptor, was higher in GCA patients with ischaemic complications. Serum NGF was significantly higher in GCA patients ( n = 28) vs. controls ( n = 48), whereas no significant difference was found for BDNF and NT-3. NGF and BDNF enhanced GCA-derived temporal artery VSMC proliferation and BDNF facilitated migration of temporal artery VSMCs in patients with GCA compared to controls. Conclusions Our results suggest that NTs and NTRs are involved in vascular remodelling of GCA. In GCA-derived temporal artery VSMC, NGF promoted proliferation and BDNF enhanced migration by binding to TrkB and p75 NTR receptors. Further experiments are needed on a larger number of VSMC samples to confirm these results.

Topic: Angiogenesis and VEGF in Cancer
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
Vliv prostředí na vývoj řeči dětí

The bachelor's thesis deals with influence of home environment on development of children's speech. It aims to describe present conditions of home environment, which completely influences the development of children?s language in the preschool age, and to identify whether children have higher level of speech when their parents read to them. The theory part deals with basic opinions on development of children's personality, and describes some present influences of environment on children, especially the influence of family and media (TV, computer). The next chapter explains the development of children's speech from birth to the end of preschool age. To the development are added possibilities of speech stimulation according to age of the child, includes using of a book as a device for development. The practical part deals with the research, which is focused on reading to children in the family, and the level of speech in the age group 3 - 4. It explains whether the reading has positive influence on quality of language. From the conclusion of research is obvious that parents read to their children relative regularly and children have average level of speech when their parents daily read to them.

Topic: Education, Psychology, and Social Research
Subfield: Education
Field: Social Sciences
Domain: Social Sciences
Negotiated employee involvement in the Societas Europaea : a new mode towards harmonization and convergence or to heterogeneity and fragmentation?

Presenting author: Prof. Dr. Berndt Keller Additional author: Frank Werner Organisation/affiliations of presenting author: Professor of Employment Relations, University of Konstanz, Germany; Address: Fach D 83, D-78457 Konstanz, E-mail: Berndt.Karl.Keller@uni-konstanz.de Organisation/affiliations of additional author: PhD-student at the chair of Prof. Berndt Keller, University of Konstanz, Germany; Address: Fach D 83, D-78457 Konstanz, E-mail: Frank.Werner@uni-konstanz.de

Topic: European Union Policy and Governance
Subfield: Political Science and International Relations
Field: Social Sciences
Domain: Social Sciences
Oxidative Metabolism in the Alveolar Macrophage: Analysis by Flow Cytometry

Abstract We evaluated the reagents dichlorofluorescin (DCFH) and hydroethidine (HE) for use in flow cytometric analysis of the respiratory burst of alveolar macrophages and monocytes. DCFH and HE are non-fluorescent precursors which can be oxidized intracellularly to the fluorescent compounds dichlorofluorescein and ethidium. Alveolar macrophages (AMs) loaded with either DCFH or HE were analyzed after phorbol myristate acetate (PMA) stimulation. The results, expressed as fmol/cell oxidation product (DCF or ethidium) after fluorometric standardization of the flow cytometer. show that both DCFH (273 ± 48, mean increase over control ± SE, fmol/cell, N = 9) and HE (416 ± 54, N = 11) detected the substantial respiratory burst of hamster AMs. Similar results were obtained with normal human AMs. By using multiparameter analyses, the oxidative response of AMs ingesting opsonized fluorescent latex beads was measured in subpopulations ingesting increasing numbers of particles. A graded increase in oxidation of both DCFH and HE was found in response to increasing phagocytosis. Ingestion of fluoresceinated staphylococcal bacteria caused similar changes in HE-loaded AMs. Inhibition of respiration with antimycin showed that approximately 95% of the increased oxidative metabolism of hamster AMs ingesting opsonized beads or bacteria was mitochondrial. The remaining 5% (10–40 fmol/cell) is membrane-derived oxidative activity quantitatively similar to that measured in assays of extracellular release of H2O2. Monocytes loaded with either DCFH or HE also showed substantial increases in fluorescence after PMA stimulation (mean % increase over control ± SE at 30 ruin: 464 ± 104, DCFH, 505 ± 156, HE). While DCHF is known to measure H2O2, HE is less well characterized. Exposure of cells to an extracellular source of both superoxide anion (O2-) and H2O2, xanthine oxidase-xanthine, resulted in marked oxidation of intracellular HE. Addition of both superoxide dismutase and catalase blocked this oxidation, indicating that HE can detect both O2- and H2O2. These agents can be useful probes for precise analysis of oxidative metabolism during phagocytosis in AMs and other mononuclear phagocytes.

Topic: Neonatal Respiratory Health Research
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
IMPACT OF GENDER DIVERSITY AND LEADERSHIP ON ORGANISATIONAL INTEGRITY IN PAKISTANI INDUSTRIAL SECTOR

Purpose of the study: The main purpose of this study is to analyse the impact of gender diversity on organisational integrity in the context of Pakistani industrial sector. This study also investigates about the influences of female leaders on the association between diversity and organisational integrity and evaluates the effect of work place diversity on increase in organisational performance.&#x0D; Methodology: This study involves mediating and moderating variables along with independent and dependent variables, therefore researcher in this study has utilised Structural equation model (SEM) and Meta Regression Analysis (MRA) for achieving the main objectives of this research. The researcher has followed the positivism research philosophy as well as deductive research approach. In this study, researcher has followed quantitative research design to attain the key objectives of this study.&#x0D; Main Findings: From the results of study, it can be suggested that employers in Pakistan should diversify their workforce and also look to hire female candidates for the same position as male candidates since it would increase the work efficiency and integrity within an organisation as women tend to work more or equally passionately in their respective fields similar to men.&#x0D; Applications of this study: So, the study of impact of gender diversity on organisational integrity in the context of Pakistani industrial sector is not only useful for IT department but also useful for all organisational where gender diversity exists.&#x0D; Novelty/Originality of this study: Finally, it is important to clarify that one of the research gap that has been identified is the difference in wages between the male and the female employees. The difference in the pay scale between the two genders is considered to be a sophisticated gap that the research can deliberately overcome.

Topic: Socioeconomic Development in MENA
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
Dealing with Danger: The Practices of Keeping and Discarding Magical Letters

Disposing of a piece of paper with a textual apotropaios might be even more problematic than storing or sharing it. A perfect example is a type of amulet named “heavenly letters”, “luck letters” or “chain letters”. Such a letter is often framed by its owner as an object or sacred/magic artifact which can act and produce non-beneficial effect on its own, without any human agency: one does not necessarily need to read or otherwise handle a luck letter to receive bad luck, while to receive good luck certain actions must be undertaken. Most often bad luck or a curse affects those who ignore or neglect a luck letter, and some of the later examples of this genre define at length different punishments for those who tear it or throw it away. Finding themselves in this situation, people turn to contemporary traditions of discarding sacred or malign artifacts. However, people often choose an intermediate strategy of giving a letter away, taking it to a specialist or discreetly passing it to a neighbor. The latter case is considered a malign magical activity. The intertwining between a luck letter as an autonomous force with a potential negative effect, “lay” senders and receivers and “specialists”, all bound together with the problem of discarding a magical object forms a complex and dynamic network of actors.

Topic: Historical, Religious, and Philosophical Studies
Subfield: Archeology
Field: Arts and Humanities
Domain: Social Sciences
THE UPTAKE AND RELEASE OF [<sup>3</sup>H]‐2‐AMINO‐6,7‐DIHYDROXY1,2,3,4‐TETRAHYDRONAPHTHALENE (ADTN) BY STRIATAL NERVE TERMINALS

A study has been made of the uptake and release of [G‐ 3 H]‐2‐amino 6,7‐dihydroxy‐1, 2,3,4‐tetra‐hydronaphthalene (ADTN) by crude striatal synaptosomes of the rat. Uptake was rapid, temperature‐dependent and could be suppressed by a variety of metabolic inhibitors. The Michaelis‐Menten kinetics indicated the presence of two distinct transport systems in the striatum which were of much higher capacity than those found in the cerebellum, which lacks dopaminergic innervation. Uptake of [ 3 H]‐ADTN was strongly inhibited by dopamine and the two potent dopamine‐uptake inhibitors, benztropine and nomifensine, but only weakly by imipramine and amphetamine (the latter in non‐reserpine‐treated animals). Accumulated [ 3 H]‐ADTN could be released from striatal slices by elevated K + . A similar release was evoked upon the addition of the ionophore, A23187. The most potent releaser of [ 3 H]‐ADTN was (+)‐amphetamine. This effect occurred at concentrations inactive against ADTN uptake. The neuroleptic ris‐flupenthixol produced an inhibition of the spontaneous release. It is concluded that [ 3 H]‐ADTN is accumulated preferentially into areas of the rat brain rich in dopamine. The pharmacological specificity of the uptake suggests that it is a good substrate for the dopamine carrier. Following uptake, [ 3 H]‐ADTN may be released by K + and a calcium ionophore, which raises the possibility that ADTN might act as a false transmitter.

Topic: Neuroscience and Neuropharmacology Research
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Clinical and endoscopist factors associated with post‐colonoscopy colorectal cancer in a population‐based sample

Abstract Aim Factors associated with verified post‐colonoscopy colorectal cancers (PCCRC) have not been well defined and survival for these patients is not well described. We aimed to assess the association of patient, tumour and endoscopist characteristics with PCCRC. Methods Using population‐based data, we identified individuals diagnosed with CRC from 1 January 2000 to 31 December 2005 who underwent a colonoscopy within 3 years prior to diagnosis. Detected cancers were those diagnosed ≤6 months following colonoscopy; PCCRC were diagnosed &gt;6 months to ≤3 years following colonoscopy. Post‐colonoscopy and detected cancers were verified through chart review using a hospital‐based simple random sampling frame. We used multivariable conditional logistic regression to determine the association of patient, tumour and endoscopist factors with PCCRC and compared overall survival using Cox proportional hazard models. Results Using the random sampling frame, we identified 498 patients with PCCRC and 498 with detected CRC; we obtained records and confirmed 367 patients with PCCRC and 412 with detected cancers. In multivariable analysis, patient age (OR 1.01; 95% CI 1.00–1.03) and tumour location (distal vs. proximal OR 0.36; 95% CI 0.25–0.53) were associated with PCCRC; endoscopist quality measures were not significantly associated with PCCRC. We did not find significant differences in overall survival between PCCRC and detected cancers (hazard ratio 1.12; 95% CI 0.92–1.32). Conclusion Although endoscopic quality measures are important for CRC prevention, endoscopist factors were not associated with PCCRC. This study highlights the need for further research into the role of tumour biology in PCCRC development.

Topic: Colorectal Cancer Screening and Detection
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Efficient use of timber resources in Mexico: Historical development and current challenges

The use and consumption of wood has always captured the attention of forest researchers, mainly from the point of view of forest management and the sustainable processing of raw materials. For this reason, the wood industry has not only been concerned with the maintenance of forests, but also with efficient processing. The objective was to identify, analyse and discuss the main elements that influence the efficient use of natural timber resources at a global, regional and local level, providing a historical and current perspective of the industrial forestry sector in Mexico. Historically, the wood industries worldwide have been concerned with applying intensive silvicultural treatments in native and artificial forest stands, in search of satisfying the demand of a growing market. In this context, industries evolved as processes needed to be more efficient. Therefore, efforts were made to reduce and take advantage of forest residues, at the same time various historical events generated additional needs. At present, the integration of silviculture and forest transformation allow to increase and improve the quality of the products generated. Through the application of intensive silvicultural treatments, products of a single species are obtained. However, it is possible to direct production to a specific market as the forest mass develops. For its part, selective treatments in uneven-aged forests maintain a constant production of diverse products for different specialized markets. In Mexico, it is imperative to analyse and generate innovative or competitive products derived from wood to improve the efficiency of forest harvesting.

Topic: Agricultural and Food Sciences
Subfield: Forestry
Field: Agricultural and Biological Sciences
Domain: Life Sciences