jimnoneill/paper-to-field-training huggingface dataset:
Proton nuclear magnetic resonance investigation of the nature of solution conformational equilibriums of monomeric insect deoxyhemoglobins

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The proton nuclear magnetic resonance spectra of the three monomeric deoxyhemoglobins of the insect larva Chironomus thummi thummi have been recorded, assigned, and analyzed. In the two allosteric hemoglobins, the heme methyls and vinyl protons were assigned by specific deuterium labeling. The hyperfine-shifted proximal histidyl imidazole exchangeable protons for the three native and two deuteroheme-reconstituted hemoglobins were assigned by comparison of spectra in H2O and 2H2O. Both native and reconstituted allosteric hemoglobins exhibit two sets of interconvertible resonances indicative of two heme orientations differing by a 180 degrees rotation about the alpha-gamma-meso axis, as previously found for the met-cyano analogues [La Mar, G. N., Smith, K. M., Gersonde, K., Sick, H., & Overkamp, M. (1980) J. Biol. Chem. 255, 66]. The relative pH sensitivities of the heme resonance hyperfine shifts for the two allosteric hemoglobins and the apparent pK approximately 8 indicate that the t in equilibrium r allosteric transition, as modulated by the Bohr proton, is being observed. For the native hemoglobins, the t in equilibrium r conformational transition was found to be centered at the heme periphery, with the proximal histidyl imidazole environment insensitive to both pH and the rotational position of the heme, consistent with the absence of a pH influence on the ligation on-rate. For the deuteroheme-reconstituted allosteric hemoglobins, both the heme and axial imidazole environments sense the t in equilibrium r transition, and the histidine environments for the two components for each hemoglobin can be clearly distinguished, suggesting that the ligation on-rates may depend on both pH and heme orientation.
Hamid Dabashi. Masters & Masterpieces of Iranian Cinema. Washington DC, Mage Publishers, 2007, 456 p.

Field: Arts and Humanities (Social Sciences)

Sous prétexte de répondre à un jeune réalisateur iranien, l’A. s’exprime sur le cinéma iranien à travers une sélection d’œuvres cinématographiques et d’auteurs-réalisateurs. Tant sur la forme que sur le fond, ce livre sur le cinéma iranien peut s’inscrire dans la continuité de son ouvrage intitulé : Close up: Iranian Cinema, Past, Présent and Future, paru en 2001. Dabashi se veut inactuel, au sens poétique et philosophique du terme, et surtout pas historien, même si à travers une douzaine de ...
Occurrence Download

Field: Agricultural and Biological Sciences (Life Sciences)

A dataset containing 218 species occurrences available in GBIF matching the query: { "and" : [ "TaxonKey is Breviceps adspersus Peters, 1882", "HasCoordinate is true", "HasGeospatialIssue is false", "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)", "Geometry POLYGON ((35.5808 -24.13,35.5909 -24.0715,30.5701 -24.0715,30.5701 -28.5786,32.4847 -28.5786,32.55 -28.5222,33.0346 -26.8668,32.9741 -26.7838,33.0415 -26.059,32.9304 -26.0011,32.7994 -26.1281,32.6834 -26.0015,32.813 -25.8728,32.8513 -25.7166,33.3048 -25.3731,35.1489 -24.6699,35.5808 -24.13))" ] } The dataset includes 218 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0031383-250525065834625/datasets/export for details. Data from some individual datasets included in this download may be licensed under less restrictive terms.
Equilibrium and kinetic studies of the association of catalytic and regulatory subunits of aspartate transcarbamoylase.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

I'*'I-Labeled catalytic and regulatory subunits were used to study the assembly of aspartate transcarbamoylase (EC 2.1.3.2;carbamoylphosphate: L-aspartate carbamoyltransferase) of Escherichia coli.The association of the two catalytic and three regulatory subunits in the oligomeric enzyme is virtually irreversible as shown by the small rate constant (less than 2 X lo-' s-') for exchange of a subunit.With labeled subunits of high specific radioactivity the pathways of assembly could be studied at protein concentrations in the nanomolar range, and the overall process which required about 20 min could be "stopped" at various times by a "chase" with unlabeled subunits.Various intermediates were "trapped" and their amounts measured after electrophoretic separation.At very low concentrations
E-Government—The Inclusive Way for the Future of Digital Citizenship

Field: Social Sciences (Social Sciences)

eGovernment brings administration closer to its citizens and entrepreneurs, speeding up, facilitating, and increasing the transparency of administrative actions, consequently saving time and money and increasing efficiency. The study aims to explore the digital divide and digital citizenship in eGovernment usage in Slovakia and Norway according to their national statistics. The study adopted quantitative secondary data from Eurostat’s individual-level database, originating from the questionnaire ‘Information and Communications Technology (ICT) use in households and by individuals’. The analysis was applied to Norwegian and Slovak data from 2021, and the research sample consists of 2145 observations from Norway and 3252 observations from Slovakia. The results show that being a beneficiary of eGovernment services aligns with sociodemographic variables to a lower extent in Norway than in Slovakia. In Slovakia, the usage of the services varies not only according to the education of the user but also according to income, even if an individual has access to the Internet and sufficient skills. Due to the high level of development, and especially the inclusive nature of eGovernment, the Norwegian approach with the implementation of electronic identification (eID), digital mailbox, contact information, Altinn, and public common registers could serve as a benchmark for the further development of public digital services—not only in Slovakia but also for other countries. The conclusion shows that there is less inequity in the possibility to use eGovernment within individual social groups in Norway than in Slovakia. Norway manifests and emplaces strategies to guarantee critical judgment, ensuring the use of digital tools with safety. Slovakia, with lower levels of digital service users, tends to experience higher levels of digital divide which make the situation with eGovernment penetration even more difficult.
Chemical Stock Prices Post Slight Gain in 1992

Field: Economics, Econometrics and Finance (Social Sciences)

RETURN TO ISSUEPREVNewsNEXTChemical Stock Prices Post Slight Gain in 1992■ Smaller firms' stocks perform better than those of major companies; biotechnology stocks fall from year-earlier levelsWILLIAM J. STORCKView Author Information C&EN Northeast News BureauCite this: Chem. Eng. News 1993, 71, 3, 20–21Publication Date (Print):January 18, 1993Publication History Published online12 November 2010Published inissue 18 January 1993https://pubs.acs.org/doi/10.1021/cen-v071n003.p020https://doi.org/10.1021/cen-v071n003.p020newsACS PublicationsCopyright © 1993 American Chemical SocietyArticle Views4Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Investigating the effectiveness of planned focus on form method in teaching young learners English as a foreign Language

Field: Arts and Humanities (Social Sciences)

This study aimed at investigating the effectiveness of planned focus on form method in the acquisition of target language forms in English. The study specifically examined the planned focus on form method and the teaching model in the textbook of the 5th graders in terms of the attainment of the objectives of the target unit ‘Health’. The participants of the study were 5th grade learners (n= 60) studying at a state secondary school in Milas in the district of Muğla province in Turkey. The research was a quasi-experimental research design in which two intact 5th grade classes were assigned as experimental and control groups. The data collected from pre-test, progress achievement tests, and the post-test were analysed using the SPSS 17.0 statistical programme. The progress achievement test scores and post-test scores of the subjects were analysed through independent samples t-test in order to analyse which instructional treatment was more effective in reaching the objectives of the unit. Repeated measures ANOVA test was also administered in order to measure the effects of the treatment in time, which indicated that both treatment types were effective in increasing the learners’ scores from pre-test to post-test. The statistical analysis of data indicated that planned focus on form was significantly more effective than the regular instruction according to the results of the progress achievement tests [t(58)= 2.67; p=0.010]. The results of the post-test did not indicate a statistically significant difference between the two groups [t(58)= -1.058: p= 0.294], the experimental group (M=60.86) performed better than the control group (M=55.06) in the post-test, though.
On the Sub-Exponential Decay of Detection Error Probabilities in Long Tandems

Field: Mathematics (Physical Sciences)

We consider the problem of decentralized binary hypothesis testing in a network of sensors arranged in a tandem. We show that the rate of error probability decay is always sub-exponential, establishing the validity of a long-standing conjecture. Under the additional assumption of bounded Kullback-Leibler divergences, we show that for all d > 1/2, the error probability is Omega(e -cnd ), where c is a positive constant. Furthermore, the bound Omega(e -c(logn)d ), for all d > 1, holds under an additional mild condition on the distributions. This latter bound is shown to be tight.
Update on Assessment of Estimated Glomerular Filtration Rate in Patients with Cirrhosis

Field: Medicine (Health Sciences)

Background: cirrhosis causes muscle loss and changes in creatinine levels, it is difficult to assess renal function in these patients. Often, creatinine-based processes calculate GFR too high which causes renal diseases to be diagnosed late and the illness to be undertreated. Objectives: To study which eGFR equation works best in cirrhotic patients and can most reliably be used in assessing and detecting early kidney impairment. Study Design: A Cross-Sectional Study. Place and Duration of study: From May 2024 to December 2024 Nephrology & Gastroenterology Department, Sandeman Provincial Hospital / Bolan Medical College / Hospital, Quetta. Methods: This cross-sectional study was performed at Nephrology & Gastroenterology Department, SPH/BMCH, Quetta. One hundred and twenty-five people with cirrhosis participated in the study. Serum creatinine, cystatin C and true GFR by radionuclide scanning were all measured. Creatinine and cystatin C, MDRD and Cockcroft-Gault formulas were used for estimating GFR. The statistical comparisons were made using version 24 of SPSS. Results: The average age among the 125 cirrhotic patients was 56.8, with a variance of 10.2 years. More men (61.6%) than women were part of the study. Compared to measured GFR, the CKD-EPI creatinine-cystatin C formula showed the best correlation (r = 0.82, p < 0.001). Both the MDRD and Cockcroft-Gault equations were found to overestimate GFR by about 11 and 15 mL per minute per square meter (p<0.01). Patients in Child-Pugh class C experienced the greatest difference between the GFR predicted and the GFR measured. Calculations that use Cystatin C gave the best outcomes in patients with more advanced liver disease. Conclusion: For people with cirrhosis, the common eGFR formulas using creatinine may give a misleading assessment of renal function. For patients with kidney disease, especially when creatinine becomes less accurate, use of CKD-EPI that includes cystatin C is the best option.
Physical Activity Intensity Among Adolescents and Association With Parent–Adolescent Relationship and Well-Being

Field: Psychology (Social Sciences)

Participation in physical activity (PA) provides young people significant health benefits, including improved well-being. However, large percentages of children and adolescents do not meet the recommendations for PA. Given that PA patterns are established during childhood and adolescence, and evolve within the context of the family, the current study explores the relationship between perceived parent–adolescent relationships and adolescents’ PA levels, body mass index (BMI), and subjective well-being. The study was conducted in Israel, and the sample included 233 participants (126 girls, 107 boys) aged 13 to 18 years. Participants self-reported the following measures: demographic information, BMI, the Godin-Shephard Leisure-Time Physical Activity Questionnaire, the Personal Well-Being Index, and parent–adolescent relationship. The data were analyzed using Pearson analyses, t tests, and regressions. A clear difference emerged in strenuous PA activity by sex [ t( 223 ) = 2.1, p < .01]; the average strenuous PA was greater for boys ( M = 3.9, SD = 2.4) than for girls ( M = 1.8, SD = .2.4). Furthermore, different predictors of strenuous PA by sex were found: for boys, parent–adolescent relationship was a significant predictor; for girls, subjective well-being was a predictor. The findings can shed light on the need for different intervention programs for adolescent boys and girls to increase their involvement in PA.
Figure 1 from: Li G-J, Li S-M, Buyck B, Zhao S-Y, Xie X-J, Shi L-Y, Deng C-Y, Meng Q-F, Sun Q-B, Yan J-Q, Wang J, Li M (2021) Three new Russula species in sect. Ingratae (Russulales, Basidiomycota) from southern China. MycoKeys 84: 103-139. https://doi.org/10.3897/mycokeys.84.68750

Field: Agricultural and Biological Sciences (Life Sciences)

Figure 1 Phylogenetic tree generated from Bayesian analysis of ITS sequences. Main clades corresponding to subsections of sect. Ingratae are indicated in colour blocks. Holotypes of the new species are shown in bold. Values of posterior probabilities (PP) of MrBayes (≥ 0.9) and bootstraps of ML and MP analyses (≥ 50) are presented above the nodes as (MLBS/PP/MPBS).
Analysis of chlorimuron ethyl in crops by high-performance liquid chromatography

Field: Agricultural and Biological Sciences (Life Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnalysis of chlorimuron ethyl in crops by high-performance liquid chromatographyJames L. Prince and Richard A. GuinivanCite this: J. Agric. Food Chem. 1988, 36, 1, 63–69Publication Date (Print):January 1, 1988Publication History Published online1 May 2002Published inissue 1 January 1988https://pubs.acs.org/doi/10.1021/jf00079a017https://doi.org/10.1021/jf00079a017research-articleACS PublicationsRequest reuse permissionsArticle Views87Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
[Pathology related to altitude].

Field: Medicine (Health Sciences)

Low atmospheric pressure at high altitude causes a reduction of partial oxygen pressure in the air. Resulting hypoxia triggers adaptive mechanisms to maintain oxygen delivery to cells at levels compatible with requirements of the body. Hyperventilation and tachycardia followed by polyglobulia are the main physiological responses. Hypoxia-related events can lead to edema of certain organs. Acute mountain sickness, high altitude pulmonary and cerebral edema are potentially serious disorders in remote areas. Since the only remedy is descending to lower altitudes, early recognition of symptoms while return is still possible is important. Use of a portable hyperbaric chamber can be an alternative if return is impossible. The potentially serious consequences of these diseases and poor effectiveness of treatment modalities underscore the need for prevention. The main preventive measures are screening to identify subjects at risk and providing information to mountaineers.
Physician–Patient Racial Concordance, Continuity of Care, and Patterns of Care for Hypertension

Field: Health Professions (Health Sciences)

To assess the effects of physician–patient racial concordance and continuity of care on hypertension outcomes, we described patterns of care for hypertension; we used cross-tabulations and repeated measures (generalized estimating equations) analyses with panel survey data from elderly persons interviewed and examined in 1987 and 1990. Continuity of care was associated with recognition of hypertension, receipt of medication, and lower incidence of undetected hypertension. Physician race had little effect, but continuity is important for successful management of hypertension in older persons.
Toward single-photon imaging at short wave infrared (SWIR)

Field: Physics and Astronomy (Physical Sciences)

We present our latest results from a novel nano-injector-base photon detector. Previously, we have demonstrated the excellent noise performance and large linear gain of single-element devices at room temperature. Here we demonstrate the first focal plane array (FPA) made from this unique device, and show that they hold their high gain and low noise performance at a good array uniformity. The high internal gain produces significantly better images at high frame rates, or at low light level conditions.
Effect of l‐caldesmon on osteoclastogenesis in RANKL–induced RAW264.7 cells

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Non‐muscle caldesmon (l‐CaD) is involved in the regulation of actin cytoskeletal remodeling in the podosome formation, but its function in osteoclastogenesis remains to be determined. In this study, RANKL‐induced differentiation of RAW264.7 murine macrophages to osteoclast‐like cells (OCs) was used as a model to determine the physiological role of l‐CaD and its phosphorylation in osteoclastogenesis. Upon RANKL treatment, RAW264.7 cells undergo cell‐cell fusion into multinucleate, and TRAP‐positive large OCs with a concomitant increase of l‐CaD expression. Using gain‐ and loss‐of‐function in OC precursor cells followed by RANKL induction, we showed that the expression of l‐CaD in response to RANKL activation is an important event for osteoclastogenesis, and bone resorption. To determine the effect of l‐CaD phosphorylation in osteoclastogenesis, three decoy peptides of l‐CaD were used with, respectively, Ser‐to‐Ala mutations at the Erk‐ and Pak1‐mediated phosphorylation sites, and Ser‐to‐Asp mutation at the Erk‐mediated phosphorylation sites. Both the former two peptides competed with the C‐terminal segment of l‐CaD for F‐actin binding and accelerated formation of podosome‐like structures in RANKL‐induced OCs, while the third peptide did not significantly affect the F‐actin binding of l‐CaD, and decreased the formation of podosome‐like structures in OCs. With the experiments using dephosphorylated and phosphorylated l‐CaD mutants, we further showed that dephosphorylated l‐CaD mutant facilitated RANKL‐induced TRAP activity with an increased cell fusion index, whereas phosphorylated l‐CaD decreased the TRAP activity and cell fusion. Our findings suggested that both the level of l‐CaD expression and the extent of l‐CaD phosphorylation play a role in RANKL‐induced osteoclast differentiation.
Trajectory prediction in North Atlantic Oceanic airspace by wind netxorking

Field: Engineering (Physical Sciences)

• Implementing new technologies enables aicraft to exchange the measured meteorological data with each other directly • The data obtained with wind networking is much more accurate than the initial estimations • Adjusted predictions of cruising time and conflicts are much closer to the reality • Wind networking evolves great amelioration of flight prediction • Wind networking is especially efficient in dense traffic conditions • Future work: to apply the concept in other dense areas (ex. big terminal maneuvering areas).
Chemoselective heterocyclization and pharmacological activities of new heterocycles--a review. Part V-Synthesis of biocidal 4-thiazolidinones derivatives.

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

4-Thiazolidinones have been reported to possess biological activity especially fungicidal activity. With an intention to prepare some more 4-thiazolidinones as drugs for anti HIV and anticancer activity, we have synthesized some more 4-thiazolidinones by the action of mercaptoacetic acid on Schiff's base and/or heterocyclization of N-substituted thioureas with monochloracetic acid. Characterization of 4-thiazolidinone was deduced upon elemental and spectral analysis.