jimnoneill/paper-to-field-training huggingface dataset:
EMPLOYEE AFFECTIVE RESPONSES TO ORGANIZATIONAL STRESS: MODERATING EFFECTS OF JOB CHARACTERISTICS

Field: Business, Management and Accounting (Social Sciences)

This research examines (a) the relative importance of each of three role variables—role conflict, ambiguity, and overload—as sources of stress and dissatisfaction among managerial‐level personnel, and (b) the moderating effects of job enrichment characteristics on the relationships between role stressors and intrinsic job satisfaction, involvement, and anxiety. Data were collected from a sample of 89 managerial personnel of a large, heavy‐equipment manufacturing company in the Midwest. Results show that role ambiguity has the strongest relationships with role responses in the predicted directions. Further, significant interactions are obtained between each of role ambiguity and role overload, but not role conflict, and job characteristics. The two role stressors tend to be more aversive for individuals on low‐enriched rather than high‐enriched jobs. Implications of the findings for work design and the management of stress are discussed.
Peer Review #2 of "Indole and 2,4-Thiazolidinedione conjugates as potential anticancer modulators (v0.1)"

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Background: Thiazolidinediones (TZDs), also called glitazones, are five-membered carbon ring molecules commonly used for the management of insulin resistance and type 2 diabetes.Recently, many prospective studies have also documented the impact of these compounds as anti-proliferative agents, though several negative side effects such as hepatotoxicity, water retention and cardiac issues have been reported.In this work, we synthesized twenty-six new TZD analogues where the thiazolidinone moiety is directly connected to an N-heterocyclic ring in order to lower their toxic effects.Methods: By adopting a widely applicable synthetic method, twenty-six TZD derivatives were synthesized and tested for their antiproliferative activity in MTT and Wound healing assays with PC3 (prostate cancer) and MCF-7 (breast cancer) cells.Results: Three compounds, out of twenty-six, significantly decreased cellular viability and migration, and these effects were even more pronounced when compared with rosiglitazone, a well-known member of the TZD class of antidiabetic agents.As revealed by Western blot analysis, part of this antiproliferative effect was supported by apoptosis studies evaluating BCL-xL and C-PARP protein expression.Conclusion: Our data highlight the promising potential of these TZD derivatives as anti-proliferative agents for the treatment of prostate and breast cancer.
Breaking down employment barriers for PWDs: Disability inclusion in the Philippine hospitality industry

Field: Social Sciences (Social Sciences)

Despite numerous local and international statutes on their acceptance in mainstream employment, persons with disabilities (PWDs) still experience various forms of discrimination. The actions that the PWDs get may result in the way how other people treat them, or the improper stereotypes that the employers perceive them to be. Hence, underemployment among PWDs is still one of the problems in the society, mainly because some are having difficulties in being employed due to their condition. Persons with Disabilities have been fighting for their rights in the workforce for a long time in the Philippines. Despite all the efforts of the government and advocacies of the private sector, employment among PWDs has been difficult and rigorous. There have been different multi-sectoral movements to lobby for change especially in the hospitality sector. Hence, focusing on the views of the key-players are the main objective of this investigation. The goal of this paper is to understand the view of government and private sectors in hiring PWDs in the hospitality establishments of the National Capital Region (NCR) of the Philippines. Phenomenology, a qualitative type of technique, was employed in the study. The researchers collected the data through semi-structured face-to-face interviews and implemented a thematic analysis to create themes based on extracted codes. The findings of this study come from the views of public and private sectors, the government’s involvement, the implementation of Republic Act 7277 or Magna Carta for PWDs, and the hiring process associated with hiring PWDs. The researchers concluded that the government and private sectors are gearing towards inclusive growth by hiring PWDs in the National Capital Region, Philippines, despite the social stigmas associated with hiring them.
FIGURE 7. A–D in Review of the Southeast Asian leafhopper genus Loeia Duan (Hemiptera: Cicadellidae: Deltocephalinae)

Field: Agricultural and Biological Sciences (Life Sciences)

FIGURE 7. A–D, Loeia serrata ovipositor: A–B, first valvula with enlargement of apex; C–D, second valvulae and gonoplac with enlargement of second valvulae apex. E–N, sternite VII: E, L. articulata; F, L. cetacea; G, L. chelata; H, L. compressa; I, L. decidua; J, L. elongata; K, L. robusta; L, L. serrata; M, L. tamtipi; N, L. tridentata. O, L. tamtipi, base of abdomen, ventral view, showing 1S and 2S apodemes; P, same showing apodemes only.
Clostridial Toxins Involved in Human Enteric and Histotoxic Infections

Field: Immunology and Microbiology (Life Sciences)

Clostridial enterotoxins Clostridium perfringens enterotoxin (CPE) Clostridium difficile toxins A and B Clostridial toxins involved in histotoxic infections The α toxin from C. perfringens Perfringolysin O from C. perfringens The α toxin from C. septicum
Isolation and characterization of organisms in high vaginal swab culture in preterm pregnancy (28-37 week)

Field: Medicine (Health Sciences)

Background: The study was performed to isolate, identify and determine the antibiotic sensitivity profile of the pathogens in the genital tract of preterm pregnant women (28 week- 37 week) gestation to the prevention of preterm delivery, pPROM, chorioamnionitis, neonatal, puerperal and maternal- foetal infections.Methods: The present perspective study in S. C. B. medical college, Cuttack was conducted in department of Obstetrics and Gynaecology from January 2014 to September 2015 in 100 patients with singleton pregnancy. The cases for study were selected randomly from the patients attending O and G OPD or admitted to the labour room or antenatal ward. Each of the patients was informed about the type, quality, and consequence of the study as well as their role in this particular participation. Valid consents were obtained from each patient who showed their cooperation. Under available aseptic conditions high vaginal swabs were collected with a commercially available collection and transport system for isolation of pathogens present in the genital tract of preterm pregnant women having gestational age 28 week-37 week. The samples were examined in the Department of Microbiology in S. C. B. medical college, Cuttack.Results: We have isolated the most common organism in preterm pregnancy is the E. coli amounting 34% followed by Candidial spp. 21%. Then comes Enterococci scoring 10%, then Staphylococci 8%, Gardenerella vaginalis 7%. Eventually Group B Streptococcus 5%. However, there is about more number of culture negative cases (no growth -24 %) according the department of Microbiology of this college. From the above study we got more number of aerobic vaginitis in contrast to bacterial vaginitis. The prevalence of pPROM was associated with E. coli i. e. 30%. Second are Enterococci having 20%. Candidial spp. Scores 18%. Gardenerella vaginalis takes 12%. However, organisms like Staphylococci and GBS comes last with a score of 6% and 2% respectively.Conclusions: As preterm birth is more associated with mother having genital infections. Our study awards the champion cup to the E. coli as it is associated with maximum number of preterm birth cases i.e. 30%. Candidial spp. comes with the number about 21% causing both symptomatic and asymptomatic infection. Enterococci and Staphylococci almost have same prevalence of preterm birth viz. 12%.
Expression of RECK in Non-Small Cell Lung Cancer Tissues and its Relationship with Prognosis

Field: Medicine (Health Sciences)

Objective To study the expression and correlation of RECK and MT1-MMP in non-small cell lung cancer(NSCLC)and clinic pathological features.Methods Immunohistochemical SP method was used to detect the expression of RECK proteins in 48 NSCLC tissues and the same para-cancerous tissues.Kaplan-Meier and Log-rank test were used to compare the survival time of positive staining group and negative staining group.Results The positive rates of RECK in NSCLC carcinoma tissues were 29.2%(14/48)which is lower than that in para-cancerous tissues 85.7%(42/48)(P0.05).The positive rates of RECK was correlated with lymph node metastasis and TNM stage.There was no relationship with age,sex,pathology subtype and histological grades,respectively.The survival time in negative RECK staining group was significent shorter than that in RECK positive staining group.Conclusion RECK is lower-expressed in NSCLC and may play an important role in invasion and metastasis of NSCLC.Low-expression of RECK suggests poor prognosis in patient with NSCLC.
SAT-666 Possible Amelioration of Diabetic State After Intravesical BCG Instillations for Bladder Cancer

Field: Medicine (Health Sciences)

Abstract Introduction - Current research provides strong evidence that intradermal Bacillus Calmette-Guerin (BCG) vaccination improves glucose metabolism by a mechanism of switching oxidative phosphorylation to aerobic glycolysis inducing a state of high glucose utilization. We present a case that demonstrates improvement in blood sugar levels upon administration of a series of intravesical BCG instillations. There is no research, in current literature, correlating blood sugars lowering after intravesical administration of BCG vaccines. Case Description - An 81 years old male with a medical history of type 2 diabetes mellitus, coronary artery disease, and bladder cancer underwent a series of BCG instillations, as therapy for his bladder cancer. He underwent BCG treatments according the Southwest oncology protocol for bladder cancer. During his BCG treatments, the patient was on Humalog 75/25, 30 units twice a day. Upon completion of his treatments, the patient experienced an episode of hypoglycemia that required hospitalization. His insulin regimen was decreased from 30 to 25 units BID. His A1C at the time of diagnosis was 8.7% and after insulin adjustments declined to 8.1%. We are reviewing a list of type II diabetic patients with bladder cancer who were treated with BCG and analyzing blood sugars before and after BCG exposure. We hypothesize that BCG vaccination precipitated the improvement in his blood sugars. Conclusion - Additional studies on BCG vaccinated, diabetic, bladder cancer patients are needed for confirmation of this effect. Our case illustrates a probable reduction in blood sugars attributable to his BCG vaccinations. Research suggests that intradermal BCG switches cellular metabolism from oxidative phosphorylation to early aerobic glycolysis. Another effect of BCG is the increasing levels of tumor necrosis factor (TNF) that leads to elimination of self-reactive white blood cells and inducing regulatory T cells. More research is needed to confirm whether intravesical administration of BCG has the same effect as intradermal BCG vaccination, which would have a potential impact on the clinical management of both type 1 and type 2 diabetic patients.
Construction of a Dual-Mode Biosensor with Ferrocene as Both a Signal Enhancer and a Signal Tracer for Electrochemiluminescent and Electrochemical Enantioselective Recognition

Field: Chemistry (Physical Sciences)

We demonstrate for the first time the construction of a dual-mode biosensor for electrochemiluminescent (ECL) and electrochemical chiral recognition of l- and d-isomers of amino acids, with ferrocene (Fc) as both a signal enhancer and a signal tracer. With the dissolved oxygen as a coreactant, ZnIn2S4 acts as the ECL emitter to generate a weak cathodic ECL signal. Fc can enter into the β-cyclodextrin (β-CD) cavity on ZnIn2S4-modified electrode as a result of host-guest interaction. Since Fc can promote H2O and O2 to produce abundant reactive oxygen species (ROS) (e.g., O2·- and ·OH), the ECL signal of ZnIn2S4 can be further amplified with Fc as a coreaction accelerator. Meanwhile, Fc molecules on the β-CD/ZnIn2S4-modified electrode can be electrochemically oxidized to Fc+ to produce a remarkable oxidation peak current. When l-histidine (l-His) is present, the matching of the l-His configuration with the β-CD cavity leads to the entrance of more l-His into the cavity of β-CD than d-histidine (d-His), and the subsequent competence of l-His with Fc on the Fc/β-CD/ZnIn2S4-modified electrode induces the decrease in both Fc peak current and ZnIn2S4-induced ECL intensity. This dual-mode biosensor can efficiently discriminate l-His from d-His, and it can sensitively monitor l-His with a detection limit of 7.60 pM for ECL mode and 3.70 pM for electrochemical mode. Moreover, this dual-mode biosensor can selectively discriminate l-His from other l- and d-isomers (e.g., threonine, phenylalanine, and glutamic acid), with potential applications in the chiral recognition of nonelectroactive chiral compounds, bioanalysis, and disease diagnosis.
Design of photonic metamaterial multi-junction solar cells using rigorous coupled wave analysis

Field: Materials Science (Physical Sciences)

We have developed a method to design multi-junction horizontally-oriented solar cells using single-layer photonic metamaterials. These metamaterial light harvesting templates are capable of separating white light into discrete wavelength ranges and trapping it efficiently into different, separately wired cavities. Any number of different wavelength-tailored charge separation complexes can be fixed to the walls of these tuned cavities. To design the metamaterials we have developed a coupled wave analysis of 2D periodic metamaterials. Past results with 1D gratings have shown that this is a very effective method for designing periodic structures and we have generalized the approach to 2D periodic cavities.
Application of the set pair analysis based on entropy and weight to efficiency evaluation of the BDAR for amphibious equipment

Field: Decision Sciences (Social Sciences)

Aiming at the particularity of the BDAR, the method which employs the set pair analysis based on entropy and weight to rational efficiency evaluation of the BDAR had been discussed by taking certain five amphibian equipments as example. Firstly, the evaluating index system was established by analyzing the characteristic of the BDAR and the factors which affect the efficiency evaluation of the BDAR. Secondly, an evaluation model of the efficiency of the BDAR was built based on the set pair analysis and entropy weight, and its weight of evaluation indexes was gained by calculating the entropy in order to form the optimization matrix. Then the equipment which has the optimal efficiency of BDAR was chosen after the five candidates being ranked by comparing their degrees of identities. At last, the theory of the set pair analysis was validated, and scientific basis of the optimum and elevation of the equipment was proved.
Barriers to entrepreneurship education coordinated by the Entrepreneurship Development Centres (EDCs) in Nigeria

Field: Business, Management and Accounting (Social Sciences)

In Nigeria however, entrepreneurship development centres (EDCs) have been created in universities, colleges and polytechnics to provide hands-on entrepreneurship education (EE) that would help reduce youth unemployment, boost employability skills, stimulate wealth creation and increase the chances of economic growth and development. Several studies in Nigeria have explored the philosophy, policy thrust and relevance of entrepreneurship education, but very few works focused on the impact of EDCs and operational barriers facing the teaching of entrepreneurship education. In bridging the gap in the literature, the chapter investigates the barriers to EE run by the EDCs in the Nigeria's higher education institutions (HEIs). To objectively investigate the barriers to EE run by the EDCs in the Nigeria's HEIs, with a view to coming up with evidence-based findings, the author adopted positivist paradigm, which entails preference for a quantitative research method and survey research design. EDCs are established by universities and other levels of HEIs to deepen entrepreneurial attitudes, spirits and mindsets among students and members of society.
A-optimal designs for heteroscedastic multifactor regression models

Field: Mathematics (Physical Sciences)

This paper searches for A-optimal designs for Kronecker product and additive regression models when the errors are heteroscedastic. Sufficient conditions are given so that A-optimal designs for the multifactor models can be built from A-optimal designs for their sub-models with a single factor. The results of an efficiency study carried out to check the adequacy of the products of optimal designs for uni-factor marginal models when these are used to estimate different multi-factor models are also reported.
Prediction Method for Perforation Corrosion Life of Coated Steel Sheets in Actual Automobiles

Field: Materials Science (Physical Sciences)

自動車用防錆鋼板の耐食性評価には様々な腐食試験法が用いられている．本研究では，各種腐食試験法による表面処理鋼板の穴あき腐食挙動を北米走行車における腐食挙動と比較した．腐食試験の結果から，亜鉛めっき鋼板の穴あき腐食挙動や耐食性支配因子が，試験条件によって異なることが分かった． 腐食試験法の実車腐食再現性を評価するために，本研究では，亜鉛めっき鋼板の穴あき腐食過程における下地鋼とZnめっきの腐食速度比に着目し，穴あき腐食指標PCI（Perforation Corrosion Index）を考案した．PCIを用いて腐食試験法と実車腐食との相関性を評価することやZn系合金めっき鋼板の実車における穴あき耐食性を予測することができる．また，実車における腐食機構を再現するためには，自動車の生産工程に合わせて試験片を作製することも重要となる．本技術の適用により，表面処理鋼板を適正且つ効率的に開発できることが期待できる．
Native growth of vertically pattened ZnO nanowire arrays under mild conditions without templates or catalysts

Field: Materials Science (Physical Sciences)

Based on the implications of a pellet experiment,we have designed and implemented a low temperature(≤90℃) approach to generate native patterned,vertically aligned ZnO nanoarrys without any templates or catalysts.This simple,economic and spontaneous patterning process offers a promising avenue for overcoming several inherent limitations of the artificial manners[1].While the purity,orientation and electrical properties of the as prepared materials allow them to be applied in various fields.
Systemic analysis of a drug trafficking mess

Field: Decision Sciences (Social Sciences)

In an effort to combat drug trafficking at the federal level, the USA faces an unenviable task. Trying to address this situation involves consideration of drug production, importation and consumption. The think-act-observe (TAO) approach of Hester and Adams (2017) provides a systems theory-based multi-methodology for addressing these and other complex, interconnected problems. After an articulation of the constituent problems of the mess and their collective stakeholders, the problems are individually subjected to systemic analysis in the think stage; further, the production problem analysis is reported in detail as a case study. These problem-level analyses are then integrated and utilised in the act stage to analyse the systemic impact of potential mess interventions. Recommendations for future action are provided in support of the observation stage. Problem owners can then move forward in an effort to resolve the mess in a manner satisfactory to all affected parties.
Female political representation in the aftermath of ethnic voilence. A comparative analysis of Burundi and Rwanda

Field: Social Sciences (Social Sciences)

We study the impact of electoral gender quotas in post-war Burundi and Rwanda on women’s political representation. First, we look at descriptive representation by studying the number of female representatives and the prestige of their positions in the legislative and executive branches of government. Second, we focus on political representation as perceived by ordinary women, before, during, and after the introduction of gender quotas. We find that, both in Rwanda and Burundi, descriptive female political representation significantly increased with the introduction of gender quotas, with the share of women in parliament and ministries consistently exceeding 30 per cent. While women still disproportionally end up in ministries of relatively lower prestige, the gap with men is closing as more women have joined the executive branches of power. We do not find any tangible effect on women’s perceived political representation. Among the possible explanations, we discuss the authoritarian nature of the regime and the crowding out of gender identity by ethnic identity. We argue that these explanations are not entirely consistent with our data and put forward a third explanation, i.e. that the perception of political representation depends on the implementation of policies—thus substantive representation, not descriptive representation—and that men and women are to a very large extent appreciative of the same policies.
Soco-net: Social care community network

Field: Health Professions (Health Sciences)

Summary: SoCo-net presents a social care network based on an innovative practice-oriented care community model that supports elderly people to remain longer indepenedent by integrating new types of advance elderly social interaction with new ways of formal and informal care provision. \nObjective: The main aim is to organize around the elderly personalized Virtual Collaborative Care Teams, consisiting of formal and informal carers, that can actively collaborate to provide ICT based elderly care in the areas of care & wellness, guidance and mobility assistance services. It focuses on end-users wishes and needs in terms of what factors, relationships and communication issues are meaningful and generate the greatest impact on the elderly self care. \nMethodology: Focus groups, structured interviews and questionnaires were applied to identify the elderly socialization needs and wishes and use case scenarios were formulated. The solution was validated by a sample of 100 end-users (including elderly, formal and informal care professionals) by the Orbis Medical & Care Group, in Netherlands. \nResults: Based on the analysis performed on the validation results, 72% of the elderly and 100% of the care professionals find it very easy to use (even without guidance). Also 84% of the elderly and 100% of the care professionals find it very useful and said that it can significantly improve their quality of life.
[Orthostatic reactions of blood circulation and autonomic regulation in healthy persons of various ages].

Field: Medicine (Health Sciences)

The age-related changes in vegetative regulation of blood circulation during active orthostatic test (AOT) have been studied in 90 practically healthy people aged from 21 to 89. The stroke blood volume was determined using the tetrapolar thoracic rheography. The basic state of the vegetative heart regulation and its changes during AOT were studied by means of the spectral analysis of the stationary rhythmograms. It is shown that intensity of both primary and secondary compensatory circulatory responses during the AOT decreases with age. An age-related impairment of the reflectory influences on heart and vessels is induced by a decreased overall vegetative tonus and insufficient activation of the sympathetic system in orthostasis. The orthostatic hypotension in elderly and old people is probably mediated by an inadequately small increment of peripheral vascular resistance and cardiac rhythm resulting from the age-related impairment of baroreceptor sympathetic control of the blood pressure.