jimnoneill/paper-to-field-training huggingface dataset:
Buddhist Attitude towards Health Related Physical Fitness in Kathmandu Valley

Field: Arts and Humanities (Social Sciences)

This study entitled “Buddhist Attitude towards Health Related Physical Fitness in Kathmandu Valley”, was carried out to find out the Buddhist attitude towards health related physical fitness. The necessary information was taken from six Monasteries and Bihars of Kathmandu Valley. Altogether, there were 310 respondents for quantitative data and six respondents for qualitative data. The major source of data was primary. The researcher used attitude scale and in-depth interview for data collection. The researcher found that the health-related physical fitness is most important aspect for improving physical condition, fighting against diseases, to reduce stress and maintaining mental fitness. Similarly, it helps us to maintain the degree of health, bodily posture, physique, proper functioning of organs and good health habits along with an adequate amount of endurance, strength, stamina and flexibility. Another finding highlighted that, through meditation and walking meditation, the body achieves a greater state of balance and breathing is regulated. Our mind becomes focused, clear, and organized. Unnecessary desires and improper thoughts are eliminated. Most of the Buddhist have had positive attitude towards health related physical fitness.
Conditional Average Treatment Effect Estimation Under Hidden Confounders

Field: Computer Science (Physical Sciences)

One of the major challenges in estimating conditional potential outcomes and conditional average treatment effects (CATE) is the presence of hidden confounders. Since testing for hidden confounders cannot be accomplished only with observational data, conditional unconfoundedness is commonly assumed in the literature of CATE estimation. Nevertheless, under this assumption, CATE estimation can be significantly biased due to the effects of unobserved confounders. In this work, we consider the case where in addition to a potentially large observational dataset, a small dataset from a randomized controlled trial (RCT) is available. Notably, we make no assumptions on the existence of any covariate information for the RCT dataset, we only require the outcomes to be observed. We propose a CATE estimation method based on a pseudo-confounder generator and a CATE model that aligns the learned potential outcomes from the observational data with those observed from the RCT. Our method is applicable to many practical scenarios of interest, particularly those where privacy is a concern (e.g., medical applications). Extensive numerical experiments are provided demonstrating the effectiveness of our approach for both synthetic and real-world datasets.
Tobramycin, amikacin, sissomicin, and gentamicin resistant Gram-negative rods.

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Sensitivities to gentamicin, sissomicin, tobramycin, and amikacin were compared in 196 gentamicin-resistant Gram-negative rods and in 212 similar organisms sensitive to gentamicin, mainly isolated from clinical specimens. Amikacin was the aminoglycoside most active against gentamicin-resistant organisms, Pseudomonas aeruginosa, klebsiella spp, Escherichia coli, Proteus spp, Providencia spp, and Citrobacter spp being particularly susceptible. Most of the gentamicin-resistant organisms were isolated from the urine of patients undergoing surgery. Gentamicin was the most active antibiotic against gentamicin-sensitive E coli, Proteus mirabilis, and Serratia spp. Pseudomonas aeruginosa and other Pseudomonas spp were most susceptible to tobramycin.
The Relative Contribution of Emotional Competence and Cognitive Ability to Individual and Team Performance

Field: Psychology (Social Sciences)

The relative contributions of emotional competence and cognitive ability to individual and team performance, team-member attitudes, and leadership perceptions were examined. Focusing on emotional competencies, we predicted that, although both cognitive ability and emotional competence would predict performance, cognitive ability would account for more variance on individual tasks, whereas emotional competence would account for more variance in team performance and attitudes. We also predicted that emotional competence would be positively related to team attitudes 220and to both leader emergence and effectiveness. Using a sample of undergraduate business majors who completed tasks alone and as members of teams, our results generally supported the hypotheses. Implications for the reach and impact of work relating emotional competencies to performance are offered.
Associations Between Amplification (1q) and Prior Cancer in a Real-World De Novo Myeloma Cohort

Field: Medicine (Health Sciences)

Abstract Genomic biomarkers inform treatment in multiple myeloma (MM), making patient clinical data a potential window into MM biology. We evaluated de novo MM patients for associations between specific MM cytogenetic patterns and prior cancer history. Analyzing a MM real-world dataset, we identified a cohort of 1769 patients with fluorescent in situ hybridization cytogenetic testing at diagnosis. Of the patients, 241 (0.14) had histories of prior cancer(s). Amplification of the long arm of chromosome 1 [amp(1q)] varied by prior cancer history (0.31 with prior cancer vs 0.24 without; 2-sided P = .02). No other MM translocations, amplifications, or deletions were associated with prior cancers. Amp(1q) and cancer history remained strongly associated in a logistic regression adjusting for patient demographic and disease attributes. The results merit follow-up regarding carcinogenic treatment effects and screening strategies for second malignancies. Broadly, the findings suggest that analyses of patient-level phenotypic-genomic real-world dataset may accelerate cancer research through hypothesis-generating studies.
Optimal Discriminant Analysis Based on Kernel Extension of Graph Embedding and Face Recognition

Field: Computer Science (Physical Sciences)

PDF HTML阅读 XML下载 导出引用 引用提醒 基于核化图嵌入的最佳鉴别分析与人脸识别 DOI: 10.3724/SP.J.1001.2011.03843 作者: 作者单位: 作者简介: 通讯作者: 中图分类号: 基金项目: 国家自然科学基金(60632050, 60873151, 60973098); 国家高技术研究发展计划(863)(2006AA01Z119) Optimal Discriminant Analysis Based on Kernel Extension of Graph Embedding and Face Recognition Author: Affiliation: Fund Project: 摘要 | 图/表 | 访问统计 | 参考文献 | 相似文献 | 引证文献 | 资源附件 | 文章评论 摘要:将压缩映射和同构映射引入核化图嵌入框架(kernel extension of graph embedding,简称KGE),从理论上了KGE 框架内的各种核算法其实质是KPCA(kernel principal component analysis)+LGE(linear extension of graph embedding,简称LGE)框架内的线性降维算法,并且基于所给出的理论框架提出了一种综合利用零空间和非零空别信息的组合方法.任何一种可以用核化图嵌入框架描述的核算法,都可以有相应的组合方法.在ORL,Yale,FERET 和PIE 人脸数据库上验证了所提出的理论和方法的有效性. Abstract:By making use of compressive mapping and isomorphic mapping in the kernel extension of graph embedding, this paper proves that the essence of kernel extension of graph embedding (KGE) is KPCA (kernel principal component analysis) plus all kinds of linear dimension reduction approaches interpreted in a linear extension of graph embedding (LGE). Based on the theory framework, a combined framework, which takes advantage of the discriminant feature in both null and non-null spaces, is developed. Furthermore, every kernel dimensionality reduction algorithm has its own corresponding combined algorithm. The experimental results from ORL, Yale, FERET and PIE face databases show that the proposed methods are better than the original methods in terms of recognition rate. 参考文献 相似文献 引证文献
Work-Based Networked Learning

Field: Social Sciences (Social Sciences)

Networked learning is an important driver for informal professional development and workplace learning based on social relationships. However powerful networked learning may be, there is a problem when it comes to making it a real asset within organizations. This may seem as a paradox, but networked learning activities are mostly invisible to others, sometimes the learners themselves might not even be aware of the learning that occurs. As a consequence networked learning in organizations goes undetected, remains off the radar of HR departments and is therefore hard to asses, manage and value (Wenger, Trayner, & De Laat, 2011). Bearing this in mind we acknowledge a great need for empirical research and tools that can raise awareness about networked learning activities to make it visible, amplify the benefits of it and strengthen the social relations through which it occurs. Through our research practice we have experimented with several visualization methods of informal learning networks (De Laat, 2011; Haythornthwaite & De Laat, 2012) and developed a research methodology around this practice, We will present the results of a descriptive study conducted with 22 teachers in a secondary school in the Netherlands alongside the design guidelines for a research practice to visualize (personal) professional development networks driven by networked learning issues. The goal of this paper is to increase our understanding of how we can make networked learning activities visible and as a consequence help organisations to support a bottom-up approach to stimulate professional development amongst teachers.
Study on Raman Spectrum Detection Method Based on Surface Enhanced Micro-nano Fiber

Field: Chemistry (Physical Sciences)

In this paper, an optical fiber Raman probe based on surface-enhanced particles is used to study the Raman spectroscopy of liquid trace substances. The optical fiber Raman detection probe uses a hollow-core fiber structure, and its air cavity as the optical excitation region of the surface-enhanced metal particles and the sample to be measured, it can form the high-efficiency action region of the sample and the excitation light, so as to achieve the perfect coincidence of the optical path and the sample cavity. Through the research on the output power of hollow fiber probe and the detection of Raman signal after inhaling different amount of samples and so on, the performance of the fiber Raman detection probe system is improved to the greatest extent. At the same time, the applicability of surface-enhanced metal particles is analyzed, and the best three kinds of metal sol, sample and hollow fiber are formed. The optimum measurement method was studied and tested. The melamine aqueous solution was measured by this method. The detection limit can reach 100 ppb. This Raman spectroscopic method is suitable for biological fluids or high-value fluids because of its small extraction of liquid samples. Its probe has low cost and is easy to mass production, which provides an effiective solution for the realization of all-optical fiber, portable and rapid detection of the whole Raman system.
Effects of Seed Coating and Osmotic Priming on the Germination of Lettuce Seeds

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract Lettuce ( Lactuca sativa L. ‘Empire’) seeds (achenes) were primed in aerated solutions of polyethylene glycol 8000 (−1.56 MPa) for 24 hr at 18°C and dried to 6% water content. Control (untreated) and primed seeds then were commercially coated in a clay-based material (Royal Sluis Splitkote). Priming prevented the occurrence of thermodormancy in seeds imbibed at temperatures between 32° and 37° and accelerated the rate of germination at all temperatures tested. Coating delayed germination slightly and reduced the maximum germination temperature of control seeds. Primed seeds exhibited thermodormancy when tested immediately after coating, but they soon regained their capacity for high-temperature germination. When tested after 5 months of storage at 5°, primed seeds germinated at temperatures up to 37° regardless of coating. Osmotically primed seeds retained the capacity for germination at high temperature after seed coating and storage, providing an effective means of improving stand establishment of direct-seeded lettuce in hot weather.
From Novice to Expert: How Expertise Shapes Motor Variability in Sports Biomechanics—a Scoping Review

Field: Medicine (Health Sciences)

ABSTRACT With expertise, athletes develop motor strategies that enhance sports performance or reduce functional costs. Motor variability is known as a relevant way to characterize these strategies in athletes with different levels of expertise. The aim of this scoping review is to gather and discuss the latest advances in the impact of expertise on motor variability during sports‐related tasks. A search encompassing three databases, Medline, SportDiscus, and Academic Search Complete, was performed. Our research methodology included three core themes: motor variability, laboratory instruments, and sports. Motor variability metrics (e.g., standard deviation and approximate entropy) and laboratory instruments (e.g., motion capture system, EMG, and force plate) were compiled. Athletes' expertise was defined by the time of deliberate practice, the performance results, or the level in which they performed. Overall, 48 of the 59 included studies determined that higher‐skilled athletes had lesser motor variability than lower‐skilled athletes. This difference in motor variability between skill levels was present within individual athletes (intra‐individual) and between athletes (inter‐individual). This result was independent of the criteria used to define expertise, the type of instrumentation used, and the metrics used to quantify motor variability.
“ENLIGHTENING THE BLACK BOX: TECHNOLOGY MOTIVATING MATHEMATICS”

Field: Arts and Humanities (Social Sciences)

Introduction Possibly referring to calculators such as the TI-92 or Casio CFX-9970G, Usiskin (1999, p. 1) relates: “[U]ser-friendly calculators have appeared that can solve literal algebraic equations, manipulate algebraic expressions, differentiate and integrate and solve systems of equations....[and which] force an examination of the amount of paper-and-pencil mathematics a person needs in
Effective Feature Representation for Clinical Text Concept Extraction

Field: Computer Science (Physical Sciences)

Crucial information about the practice of healthcare is recorded only in free-form text, which creates an enormous opportunity for high-impact NLP. However, annotated healthcare datasets tend to be small and expensive to obtain, which raises the question of how to make maximally efficient uses of the available data. To this end, we develop an LSTM-CRF model for combining unsupervised word representations and hand-built feature representations derived from publicly available healthcare ontologies. We show that this combined model yields superior performance on five datasets of diverse kinds of healthcare text (clinical, social, scientific, commercial). Each involves the labeling of complex, multi-word spans that pick out different healthcare concepts. We also introduce a new labeled dataset for identifying the treatment relations between drugs and diseases.
Amyloid β Perturbs Cu(II) Binding to the Prion Protein in a Site-Specific Manner: Insights into Its Potential Neurotoxic Mechanisms

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Amyloid β (Aβ) is a Cu-binding peptide that plays a key role in the pathology of Alzheimer's disease. A recent report demonstrated that Aβ disrupts the Cu-dependent interaction between cellular prion protein (PrPC) and N-methyl-d-aspartate receptor (NMDAR), inducing overactivation of NMDAR and neurotoxicity. In this context, it has been proposed that Aβ competes for Cu with PrPC; however, there is no spectroscopic evidence to support this hypothesis. Prion protein (PrP) can bind up to six Cu(II) ions: from one to four at the octarepeat (OR) region, producing low- and high-occupancy modes, and two at the His96 and His111 sites. Additionally, PrPC is cleaved by α-secretases at Lys110/His111, yielding a new Cu(II)-binding site at the α-cleaved His111. In this study, the competition for Cu(II) between Aβ(1-16) and peptide models for each Cu-binding site of PrP was evaluated using circular dichroism and electron paramagnetic resonance. Our results show that the impact of Aβ(1-16) on Cu(II) coordination to PrP is highly site-specific: Aβ(1-16) cannot effectively compete with the low-occupancy mode at the OR region, whereas it partially removes the metal ion from the high-occupancy modes and forms a ternary OR-Cu(II)-Aβ(1-16) complex. In contrast, Aβ(1-16) removes all Cu(II) ions from the His96 and His111 sites without formation of ternary species. Finally, at the α-cleaved His111 site, Aβ(1-16) yields at least two different ternary complexes depending on the ratio of PrP/Cu(II)/Aβ. Altogether, our spectroscopic results indicate that only the low-occupancy mode at the OR region resists the effect of Aβ, while Cu(II) coordination to the high-occupancy modes and all other tested sites of PrP is perturbed, by either removal of the metal ion or formation of ternary complexes. These results provide important insights into the intricate effect of Aβ on Cu(II) binding to PrP and the potential neurotoxic mechanisms through which Aβ might affect Cu-dependent functions of PrPC, such as NMDAR modulation.
The Natural Foundation and Realization Path of the Recreation Function of the Qinghai-Tibet plateau National Park Group

Field: Environmental Science (Physical Sciences)

PDF HTML阅读 XML下载 导出引用 引用提醒 青藏高原国家公园群游憩功能的自然基础与实现路径 DOI: 10.5846/stxb202005181261 作者: 作者单位: 作者简介: 通讯作者: 中图分类号: 基金项目: 第二次青藏高原综合科学考察研究（2019QZKK0401）；中国科学院A 类战略性先导科技专项（XDA20020302）；三江源国家公园联合研究专项（LHZX-2020-05） The Natural Foundation and Realization Path of the Recreation Function of the Qinghai-Tibet plateau National Park Group Author: Affiliation: Fund Project: 摘要 | 图/表 | 访问统计 | 参考文献 | 相似文献 | 引证文献 | 资源附件 | 文章评论 摘要:研究青藏高原国家公园群游憩功能有助于发挥其生态系统服务价值，促进青藏高原可持续发展，并为中国国家公园建设提供参考。阐述游憩功能的理论基础，分析游憩功能的定义与特征，探讨青藏高原国家公园群游憩功能的自然基础并提出实现路径。主要结论有：（1）游憩功能是生态地理要素形成的对人类游憩活动的支撑或保障程度，具有属性依赖性、潜在性、可实现性3个特征；（2）生态地理要素是形成游憩功能的自然基础。青藏高原国家公园群游憩功能的自然基础包括地形地貌、地表覆被、独特景观、生态区系、气候条件等方面，这些条件共同影响青藏高原国家公园群的游憩利用适宜性与游憩利用承载力；（3）青藏高原国家公园群游憩功能的实现路径包括合理形式、生态设施、影响控制、特许经营与协作共享。 Abstract:Studying the recreational function of the Qinghai-Tibet Plateau National Park Group can help promote the sustainable development of the Qinghai-Tibet Plateau and provide a reference for the construction of national parks in China. This article traces the theoretical basis of recreational function, clarifies the definition, characteristics and application direction of recreational function. Then, we analyze the natural basis of recreational function of the Qinghai-Tibet Plateau National Park Group and propose the realization path. The main conclusions are showed as follows. (1) The recreational function is the degree of support or guarantee of human recreational activities formed by ecological geographical elements, with three characteristics of attribute dependence, potential, and achievability. (2) Ecological geographical elements are the formation of recreational functions. The natural foundation of the recreational function of the Qinghai-Tibet Plateau national park includes topography, land cover, unique landscape, ecological flora, and climatic conditions. These conditions jointly affect the suitability of recreational development of the Qinghai-Tibet Plateau National Park Group carrying capacity with recreational development. (3) The realization path of the recreational function of the Qinghai-Tibet Plateau National Park Group includes reasonable forms, ecological facilities, impact control, franchising and collaborative sharing. 参考文献 相似文献 引证文献
Analysis of the treadmilling model during metaphase of mitosis using fluorescence redistribution after photobleaching.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

One recent hypothesis for the mechanism of chromosome movement during mitosis predicts that a continual, uniform, poleward flow or "treadmilling" of microtubules occurs within the half-spindle between the chromosomes and the poles during mitosis (Margolis, R. L., and L. Wilson, 1981, Nature (Lond.), 293:705-711). We have tested this treadmilling hypothesis using fluorescent analog cytochemistry and measurements of fluorescence redistribution after photobleaching to examine microtubule behavior during metaphase of mitosis. Mitotic BSC 1 mammalian tissue culture cells or newt lung epithelial cells were microinjected with brain tubulin labeled with 5-(4,6-dichlorotriazin-2-yl) amino fluorescein (DTAF) to provide a fluorescent tracer of the endogenous tubulin pool. Using a laser microbeam, fluorescence in the half-spindle was photobleached in either a narrow 1.6 micron wide bar pattern across the half-spingle or in a circular area of 2.8 or 4.5 micron diameter. Fluorescence recovery in the spindle fibers, measured using video microscopy or photometric techniques, occurs as bleached DTAF-tubulin subunits within the microtubules are exchanged for unbleached DTAF-tubulin in the cytosol by steady-state microtubule assembly-disassembly pathways. Recovery of 75% of the bleached fluorescence follows first-order kinetics and has an average half-time of 37 sec, at 31-33 degrees C. No translocation of the bleached bar region could be detected during fluorescence recovery, and the rate of recovery was independent of the size of the bleached spot. These results reveal that, for 75% of the half-spindle microtubules, FRAP does not occur by a synchronous treadmilling mechanism.
Ovarian Cancer Metastasis: A Unique Mechanism of Dissemination

Field: Medicine (Health Sciences)

Ovarian cancer is the most lethal of all gynecologic malignancies and has witnessed minimal improvements in patient outcomes in the past three decades. About 70% of ovarian cancer patients present with disseminated disease at the time of diagnosis. The standard of care remains a combination of debulking surgery and platinum‐ and taxanes‐based cytotoxic chemotherapy. Even though metastasis is the leading cause of ovarian cancer related fatalities, our understanding of the process remains limited. Ovarian cancer has a unique pattern of metastasis where the hematogenous spread is less common. Ovarian cancer cells mainly metastasize within the peritoneal cavity, which involves exfoliation from the primary tumor, survival, and transport in the peritoneal fluid followed by metastatic colonization of the organs within the peritoneal cavity. A key step for successful metastasis is their attachment and productive interactions with the mesothelial cells covering the metastatic organs for the establishment of metastatic tumors. This chapter provides an overview of ovarian cancer metastasis highlighting the unique dissemination and the underlying mechanisms of regulation of the steps involved. The role of the microenvironment in the process of metastasis will also be reviewed.