jimnoneill/paper-to-field-training huggingface dataset:
[Gnathostoma larvae investigation in fresh water fishes in the valley of Chinese Chang River and the morphological characteristics of the larvae].

Field: Veterinary (Health Sciences)

An investigations were carried out on the prevalence of larval gnathostomes in fresh water fishes in southeast area of the Yang-tze Valley, the people's Republic of China, from October to November. The fishes were collected from five districts which were from Shanghai, Chenchiang, Nanching, Chiuchiang and Nanchang, especially the Shanghai district involved Kunshan, Tienshanhu, Chingpu and Nanhui areas. Species of the fishes collected were Channa argus (110), Siniperca chuatssi (24) and Silurus asotus (39). A total number of fishes examined were 137. Muscles of the fishes were each dissected into small pieces and sliced. These slices were examined under a dissecting microscope. The fish viscera from 4-5 individuals were mixed, homogenized and digested by the artificial gastric juice at 37 degrees C overnight. As a result, four encysted larvae were recovered from the muscles of four fish of C. argus. 34 larvae in total were obtained by the digesting. Those larvae mainly recovered from the viscera. The morphological examination showed those 38 larvae could divide into three groups by their body lengths such as 0.58-0.86 mm (group A), 1.12-2.61 mm (group B) and 4.86 mm (group C). Group A consisted of 5 which belong to the early third-stage parasitologically which usually lives the first intermediate host. The majority (32) belongs to group B. Unfortunately, only one larva was obtained in group C which belongs to the advanced third-stage which usually lives in the second intermediate host. Light and scanning electron microscopy revealed that group A and B had the characteristics of G. hispidum and group C had those of G. spinigerum. Next, we investigated fishes near the tow big lakes, Hongtze-hu and Tai-hu situated along the river. In these lakes 12 genera, 12 species fishes (533 individuals) were captured. From these fishes 18 ganathostome larvae collected. Most of the larvae obtained from C. argus and Monopterus albus. All these larvae belongs group B which identified as G. hispidum. In conclusion, many fishes have only G. hispidum of stage of the early third in their viscera.
[Bone evaluation in ten adults with cutaneous mastocytosis].

Field: Medicine (Health Sciences)

This study suggests better investigation of bone density and bone marrow in patients who have cutaneous mastocytosis. Systematic histopathology of bone marrow and osteodensitometry help to detect patients with systemic involvement. Bone densitometry is particularly effective for early detection of patients at risk for fracture and is of practical interest since patients with osteoporosis can now be treated with Pamidronate.
Quantum Computing and Control by Optical Manipulation of Molecular Coherences: Towards Scalability

Field: Physics and Astronomy (Physical Sciences)

Abstract : Principles of quantum computing using molecular vibronic states and time-frequency resolved coherent anti-stokes Raman scattering (TFRCARS) were demonstrated through, and the execution of standard algorithms were elaborated along with measures of fidelity. These proof-of-principle implementations are on ensembles of molecules in the gas phase, unlikely to be a realistic architecture in practical implementations. We have therefore focused on solid-state implementations of the same, where now the understanding and control of decoherence of systems in intimate contact with their surrounding environment is the key scientific challenge. Very significant progress in this regard has been made in, (a) developing the tools to probe quantum coherence and decoherence of vibronic states in phase space, (b) developing semi-classical methods for the analysis of the mechanics of decoherence, (c) demonstrating mesoscopic coherence (cat-states) and complete arrest of decoherence in stationary non-eigenstates prepared by environmentally induced coherence. Also, significant progress has been made in approaching the single molecule limit in TFRCARS implementations - a crucial step in considering scalable quantum computing using the molecular Hilbert space and nonlinear optics.
Designed heterodimerizing leucine zippers with a ranger of pIs and stabilities up to 10−15 M

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract We have designed a heterodimerizing leucine zipper system to target a radionuclide to prelocalized noninternalizing tumor‐specific antibodies. The modular nature of the leucine zipper allows us to iteratively use design rules to achieve specific homodimer and heterodimer affinities. We present circular‐dichroism thermal denaturation measurements on four pairs of heterodimerizing leucine zippers. These peptides are 47 amino acids long and contain four or five pairs of electrostatically attractive g ↔ e′ (i, i′ +5) interhelical heterodimeric interactions. The most stable heterodimer consists of an acidic leucine zipper and a basic leucine zipper that melt as homodimers in the micro (T m = 28°C) or nanomolar (T m = 40°C) range, respectively, but heterodimerize with a T m >90°C, calculated to represent femtamolar affinities. Modifications to this pair of acidic and basic zippers, designed to destabilize homodimerization, resulted in peptides that are unstructured monomers at 4 μM and 6°C but that heterodimerize with a T m = 74°C or K d(37) = 1.1 × 10 −11 M. A third heterodimerizing pair was designed to have a more neutral isoelectric focusing point (pI) and formed a heterodimer with T m = 73°C. We can tailor this heterodimerizing system to achieve pharmacokinetics aimed at optimizing targeted killing of cancer cells.
Generalized network flow techniques for dynamic voltage scaling in hard real-time systems

Field: Computer Science (Physical Sciences)

Energy consumption is an important performance parameter for portable and wireless embedded systems. However, energy consumption must be carefully balanced with real-time responsiveness in hard real-time systems. We present an optimal offline dynamic voltage scaling (DVS) scheme for dynamic power management in such systems. A generalized network flow model for the uniprocessor DVS problem is developed and solved optimally using an efficient network flow algorithm. The proposed method outperforms existing DVS schemes for several popular embedded processors where the number of processor speeds is limited to a few values. The GNF model provides theoretical lower bounds on energy consumption using DVS in hard real-time systems.
Membranous laryngotracheobronchitis (membranous croup)

Field: Medicine (Health Sciences)

Membranous laryngotracheobronchitis (membranous croup), not previously described as a distinct entity, is characterized by diffuse inflammation of the larynx, trachea, and bronchi with adherent or semiadherent mucopurulent membranes in the subglottic trachea (conus elasticus) and in the upper trachea distal to the conus elasticus. We reviewed 28 cases of membranous croup diagnosed by endoscopy and/or radiographic examination. The importance of the recognition of membranous croup as a distinct entity is discussed. The characteristic radiologic findings consist of subglottic tracheal narrowing, irregularity of contour of the proximal tracheal mucosa, and sometimes detached or partially detached proximal tracheal membranes, which can be mistaken for tracheal foreign bodies.
Women health: Psychological and most prominent somatic problems in 3-year follow-up in Bosnian refugees

Field: Medicine (Health Sciences)

Background: Little is known about gender differences among people exposed to war related trauma. Aim of this study is to explore gender differences in health status and comorbidity of mental and physical disorders in a cohort of Bosnian refugees followed up for 3 years (1996–1999). Methods: This longitudinal study included 534 subjects followed up for 3 years. The interviews were conducted in refugee camps in Varaždin, Croatia in Bosnian language. Data were collected using Harvard Trauma Questionnaire (Bosnian version) and Hopkins Checklist-25, respectively. Physical health disorders were self-reported. Results: In both assessments there was a statistically significant difference between men and women in the number of physical health disorders, even when results were controlled for educational status. Although there was no difference in total number of symptoms in both assessments ( F = 0.32; df = 1; p > 0.05 and F = 1.15; df = 1; p > 0.05), important physical health disorders were significantly more frequent among women than in men in different educational groups, namely high blood pressure and cardiovascular diseases, arthritis, and anaemia. Asthma, tuberculosis, cirrhosis of the liver, ulcer and epilepsy were more frequent in men than in women. There were no differences in frequencies of psychiatric disorders at baseline, but frequency of psychiatric disorders in women was higher at endpoint for uneducated respondents. There was significant difference compared to men in group of respondents without formal education, but only in comorbidity of PTSD and depression which was more often present in females (22.1%) than in males (3.6%). Conclusion: Our findings indicate the importance of gender and education on mental and physical health of people exposed to warrelated trauma. Long term health monitoring and programs, especially related to women’s health are needed in order to avoid lasting consequences.
Clinical significance of Src expression and activity in human neoplasia.

Field: Medicine (Health Sciences)

Src, a 60 kDa non-receptor tyrosine kinase, is the product of normal c-src of the human genome and member of the Src protein tyrosine kinases family (SFK). As described by Martin and Rous, a genetic recombination between c-src and the RSV oncogene of Rous sarcoma virus results in a modified Src protein, with increased intrinsic activity and transforming potential in animal and human tissues. Several in vitro and in vivo studies supported this theory providing insight in the signalling pathways involved. Accumulating evidence from studies on clinical samples supported the role of Src in the process of carcinogenesis and disease progression in several human malignancies. Some studies have further reinforced the significance of the kinase in malignacy by correlating its expression and/or activity with important clinicopathological parameters, such as tumour stage, histopathological grade, proliferative capacity and most importantly patient's survival. This review is a comprehensive report of the published evidence on the expression and clinical significance of Src in human malignancy, which constitutes the background of the current studies and clinical trials on the use of Src inhibitors as novel potent antineoplastic strategy.
Relationship of Workload and Double Role With Work Fatigue on Batik Craftsmen

Field: Health Professions (Health Sciences)

<p><em><em>Background: In Batik Mawar, almost all work is done manually using the hands and upper arms on a continuous basis combined with the rigor of work and the use of traditional tools. The work has a heavy workload because all the work process is done by the same craftsman causing fatigue besides that the worker also have double role. The purpose of this study is to determine the relationship between workload and dual role with feelings of fatigue on craftsmen batik roses.Method: This research is Quantitative research with Cross Sectional research design. The population in this study are all artisans in Batik Mawar. Sampling in this study using total sampling technique with the number of research samples as many as 40 respondents. Data analysis used by Univariat and Bivariat.Result: Result of data analysis using Chi-Square test for work load got value p-Value = 0,001. The result of data analysis using Chi-square test for double role got p-value = 0,031. Thus it is concluded that there is a meaningful relationship between workload and dual role with feeling tired. We recommend that craftsmen wash clothes 2 times a day, cook ready meals, other than together in completing the work at home</em></em></p><p><em><br /></em></p><p><em>Di Batik Mawar, hampir semua pekerjaan dikerjakan secara manual menggunakan tangan dan lengan atas secara berkesinambungan yang dikombinasi dengan ketelitian kerja dan penggunaan alat-alat tradisional. Pekerjaan mempunyai beban kerja yang berat dikarenakan semua proses kerja dilakukan oleh pengrajin yang sama sehingga menimbulkan kelelahan</em><em> disamping itu pekerjanya juga memiliki peran ganda</em><em>.</em><em> Tujuan penelitian ini adalah untuk mengetahui hubungan beban kerja dan peran ganda dengan perasaan lelah pada pengrajin batik mawar.Metode: </em><em>Penelitian ini merupakan penelitian Kuantitatif dengan desain penelitian Cross Sectional. Populasi dalam penelitian ini adalah semua pengrajin di Batik Mawar. Pengambilan sampel pada penelitian ini menggunakan teknik total sampling dengan jumlah sampel penelitian sebanyak 40 responden. Analisis data yang digunakan Univariat dan Bivariat.</em><em>Hasil: </em><em>Hasil analisis data yang menggunakan uji Chi-Square untuk beban kerja didapatkan nilai p-Value = 0,001. Hasil analisis data yang menggunakan uji Chi-square untuk peran ganda didapatkan nilai p-value= 0,031. Dengan demikian disimpulkan bahwa ada hubungan yang bermakna antara beban kerja dan peran ganda dengan perasaan lelah.Sebaiknya pengrajin mencuci pakaian 2 kali sehari, memasak makanan siap saji, selain itu dengan cara bersama-sama dalam menyelesaikan pekerjaan dirumah.</em><em></em></p><strong><em></em></strong>
Research on comprehensive method of equipment update decision

Field: Decision Sciences (Social Sciences)

Aiming at the decision-making problem of equipment update, this article judges the relationship between the equipment's natural life, technical life and economic life, considers five update schemes of the equipment maintenance and replacement, and gives a comprehensive update decision-making process. From the perspective of economic trade-offs, this paper establishes the equipment present value cost model and the unit use cost model to determine the optimal update schemes.
Glomus Tumor in the Left Submandibular Region: A Rare Case Report and Literature Review

Field: Medicine (Health Sciences)

ABSTRACT Background Glomus tumors are rare, benign mesenchymal neoplasms predominantly located in subungual regions of the extremities. Their occurrence in the mandibular region is exceptionally uncommon, presenting unique diagnostic challenges. Only a limited number of submandibular glomus tumors have been documented, leaving their presentation and management largely underexplored. Case We presented a case of glomus tumor in the submandibular area of a 60‐year‐old female, which appeared as a purplish‐red lesion. In the absence of characteristic symptoms such as tenderness and cold sensitivity, the lesion was initially misdiagnosed as a pigmented nevus. Histopathological analysis subsequently confirmed the diagnosis as a glomus tumor. Immunohistochemical (IHC) staining further confirmed the tumor's smooth muscle and mesenchymal origins, with positive for Vimentin, SMA, Syn, Actin, Desmin, and CD34. The patient underwent surgical tumor excision with no recurrence after 28 months of follow‐up. Conclusion This case underscores the importance of considering glomus tumors in atypical locations and highlights the need for a comprehensive diagnostic approach to prevent misdiagnosis. Surgical excision remains the primary treatment, with extended postoperative surveillance recommended to monitor for recurrence.
The coupling of thermodynamics with the organizational water-protein intra-dynamics driven by the H-bonds dissipative potential of cluster water

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The Red cell-Hb-CSF functions as a sensor adapting response to Hb heterotropic equilibriums. At the lungs O2 and Mg2+, each one increasing affinity for the other stabilize the relax (R) form [(O2)4Hb(Mg)2].(H2O)R. At tissue level, the inclusion of H+ and 2,3-DPG excludes O2 and Mg2+ to stabilize the tense (T) form 2,3-DPG-deoxyHb-(H2O)T. Both senses are integrated into a cycle T into R and R into T, without involving a direct reversal. The dissipative potential of water cluster (H2O)n interacts with the hydrophilic asymmetries of Hb, to restrict randomness of the kinetic sense implicated in a single peak for activation energy (Ea). The hydration shells could sequence an enhanced Ea into several peaks, to sequentially activate transitions states. Hence, changes in dipole state, sliding, pKa, n-H-bonds, etc., could became concatenated for vectoriality. (H2O)n by the loss of H-bonds couple with to the hydration turnover of proteins and ions to result in incomplete water cluster (H2O)n*, with a lower-n. (H2O)n* became a carrier of heat/entropy into the cerebrospinal fluid (CSF) which has to be replaced 3.7 times per day. OxyHb formation involves sliding-down of alpha vs beta chains, to shift alpha1 and alpha2 Pro 44 into allowing the entrance of a fully hydrated [Mg.(H2O)6](H2O)12-14(2+) (or Zn2+) into the hydrophilic beta2-alpha1 and beta1-alpha2 interfaces. OxyHb pKa of 6.4 leads to H+-dissociation increasing negative charge of R-groups. This at beta2-alpha1 sequence two tetradentate chelates, first an Mg2+, bonding with beta2 His 92 and a second Mg2+ with alpha1 His 87, to cooperatively release hindrance. The interconversion of oxy-to-deoxyHb, pKa=8, leads to the amphoteric imidazole to became positively charged and proximal histidines return into hindrance position, releasing the incomplete hydrated Mg.(H2O)inc(2+) and O2 into CSF.
Effects of valence and arousal on working memory performance in virtual reality gaming

Field: Psychology (Social Sciences)

The role of affective states in cognitive performance has long been an area of interest in cognitive science. Recent research in game-based cognitive training suggest that cognitive games should incorporate real-time adaptive mechanisms. These adaptive mechanisms would change the game’s difficulty according to the player’s performance in order to provide appropriate challenges and thus, achieve a real cognitive improvement. However, these mechanisms currently ignore the effects of valence and arousal on the player’s cognitive skills. In this paper we investigate how working memory (WM) performance is affected when playing a VR game, and the effects of valence and arousal in this context. To this aim, a custom video game was created for Desktop and VR. Three difficulty levels were designed to evoke different levels of arousal while maintaining the same memory load for each difficulty level. We found an improvement in WM performance when playing in VR compared to Desktop. This effect was particularly pronounced in those with a low WM capacity. Significantly higher levels of valence and arousal were self-reported when playing in VR.We explore the impact that reported affective states could have in the player’s WM performance. We suggest that high levels of arousal and positive valence can lead players to a flow state [1] that may have a positive impact on the player’s WM performance.
Phosphate free perfusion prevents washout of tissue creatine in Langendorff perfused rabbit heart.

Field: Medicine (Health Sciences)

Rabbit hearts were perfused with Krebs-Henseleit bicarbonate buffer supplemented with 15 mM glucose and 10 mU/ml of insulin +/- Pi. At the end of 60 min the hearts were freeze-clamped and the content of ATP, creatine phosphate, creatine, lactate, pyruvate, DHAP and 3-P glycerate were determined enzymatically in neutralized perchloric acid tissue extracts. The free cytosolic ADP and Pi and the cytosolic NAD+ redox and phosphorylation potentials were calculated from the measured metabolite concentrations. Pi free perfusion resulted in increased creatine, free cytosolic ADP and cytosolic phosphorylation potential, decreased calculated free Pi and no change in cardiac ATP and creatine phosphate content. The increase in the cytosolic phosphorylation potential was due to the lowering of cytosolic free Pi. The increase in ADP was due to the increase in creatine. The increase in creatine appeared to be due to an inhibition of creatine efflux from the heart during Pi free perfusion which was mediated by an enhanced Na+ electrochemical gradient.
In: ed. Denis Fisette, Consciousness and Intentionality: Models and Modalities of

Field: Arts and Humanities (Social Sciences)

and logical form of perceptual reports, direct and indirect? Each of these questions has been the subject of recent discussion. In what follows I set out one answer to each of them and explore some of the ways these answers support and complement each other. The answers adopted are: to perceive- and I shall normally only have in mind visual perception- is not to judge or to conceptualize but a sui generis mental mode or activity involving non-conceptual content; perception is of particulars only; the complements of perceptual verbs are, with one exception, non-propositional and indirect perceptual reports are made true by direct perceptual relations between subjects and particulars of various sorts. Perhaps the most basic and certainly the most familiar connection between the psychological, ontological and semantic aspects of perception is provided by the following two claims. First, that the syntactic difference between the complements in “Sam saw Mary ” and “Sam saw that Mary was happy ” is correlated with the ontological difference between the two types of referent of the two complements, an individual and a state of affairs (situation, singular proposition, fact) where the latter is understood to be an abstract entity “containing ” a thing and another abstract entity, a property. Second, that seeing Mary, unlike seeing that, need involve no judgement or belief1. Thanks to Warnock and Dretske such distinctions are now familiar. Simple, direct seeing is attributed by perceptual reports containing non-propositional,