MP78-19 CHALLENGING THE USE OF COLOR DOPPLER DUPLEX ULTRASOUND IN THE PRESENT ERA: FINDINGS FROM TWO DIFFERENT SCENARIOS IN THE EVERYDAY CLINICAL PRACTICE

Field: Medicine (Health Sciences)

You have accessJournal of UrologySexual Function/Dysfunction: Evaluation II (MP78)1 Apr 2020MP78-19 CHALLENGING THE USE OF COLOR DOPPLER DUPLEX ULTRASOUND IN THE PRESENT ERA: FINDINGS FROM TWO DIFFERENT SCENARIOS IN THE EVERYDAY CLINICAL PRACTICE Walter Cazzaniga, Paolo Capogrosso, Davide Oreggia, Nicolò Schifano, Luca Boeri, Edoardo Pozzi*, Luigi Candela, Eugenio Ventimiglia, Federico Belladelli, Giuseppe Fallara, Andrea Baudo, Costantino Abbate, Vincenzo Mirone, Francesco Montorsi, and Andrea Salonia Walter CazzanigaWalter Cazzaniga More articles by this author , Paolo CapogrossoPaolo Capogrosso More articles by this author , Davide OreggiaDavide Oreggia More articles by this author , Nicolò SchifanoNicolò Schifano More articles by this author , Luca BoeriLuca Boeri More articles by this author , Edoardo Pozzi*Edoardo Pozzi* More articles by this author , Luigi CandelaLuigi Candela More articles by this author , Eugenio VentimigliaEugenio Ventimiglia More articles by this author , Federico BelladelliFederico Belladelli More articles by this author , Giuseppe FallaraGiuseppe Fallara More articles by this author , Andrea BaudoAndrea Baudo More articles by this author , Costantino AbbateCostantino Abbate More articles by this author , Vincenzo MironeVincenzo Mirone More articles by this author , Francesco MontorsiFrancesco Montorsi More articles by this author , and Andrea SaloniaAndrea Salonia More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000964.019AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: We sought to i) evaluate the prevalence of Color Doppler Duplex Ultrasound (CDDU) parameters suggestive for arteriogenic erectile dysfunction (ED) in men without known cardiovascular risk factors (CVD); and ii) to depict CDDU findings at different ages METHODS: Data from the last 125 consecutive patients evaluated at a single academic outpatient clinic were analyzed. All patients underwent dynamic CDDU. Arterial deficiency was diagnosed for PSV < 25 cm/sec and venogenic deficiency for RI < 0.85. According to comorbid CVD risk factors (e.g. overweight/obesity, hypertension, diabetes mellitus, hypercolesterolemia, smoking status), the patients were segregated in two groups (CVD- vs. CVD+); descriptive statistics was applied to evaluate the prevalence of CDDU parameters suggestive for arteriogenic ED in CVD- individuals. Moreover, descriptive statistics and multivariable logistic regression analysis with local polynomial smoothing method was used to calculate the probability of pathological findings at different ages RESULTS: Of 125 patients, 56 (44%) were CVD- and 74 (56%) CVD+. Patients CVD- were younger (median (IQR) 44.0 (36.0 – 56.2) vs. 51.0 (43 – 60); p = 0.05) and had a lower BMI (24.9 (22.8-26.7) vs. 26.1 (24.4 – 29.3); p = 0.003). In the CVD+ group, hypertension (49.3%) was the most common risk factor, followed by cigarette smoking (46.4%) and diabetes mellitus (10.3%). Overall, 51.7% vs. 56.6% CDDU were suggestive for any vascular dysfunction in CVD- vs. CVD+ patients. Of CVD-, 7.1% patients showed an arteriogenic ED vs. 12.6% in the CVD+ group (p=0.8). As for age classification, 35 (28%) patients were < 40 years, 65 (52%) were between 40 and 60 years, and 25 (20%) men were > 60 years at the time of CDDU assessment. The prevalence of pathological CDDU parameters increased throughout ageing (34.3% vs. 61.5% vs. 64.2%), with an increased prevalence of both arteriogenic and venogenic dysfunction (5.7% vs. 12.3% vs. 8% and 28.6% vs. 49.2% vs. 56.0%), respectively. At MVA model, the probability of having normal CDDU parameters ranged between from 76% <40 years of age to 28% at 75 years of age CONCLUSIONS: Despite the absence of any CVD, a non-negligible proportion of men with ED suffers from an arteriogenic dysfunction. Moreover, our findings elucidate a strict relationship between CDDU parameters and age, with less than one third of cases presenting with normal parameters at 75 years of age. These findings may be helpful to further improve the selection of the appropriate candidates for dynamic CDDU during the ED diagnostic work-up Source of Funding: / © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e1180-e1181 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Walter Cazzaniga More articles by this author Paolo Capogrosso More articles by this author Davide Oreggia More articles by this author Nicolò Schifano More articles by this author Luca Boeri More articles by this author Edoardo Pozzi* More articles by this author Luigi Candela More articles by this author Eugenio Ventimiglia More articles by this author Federico Belladelli More articles by this author Giuseppe Fallara More articles by this author Andrea Baudo More articles by this author Costantino Abbate More articles by this author Vincenzo Mirone More articles by this author Francesco Montorsi More articles by this author Andrea Salonia More articles by this author Expand All Advertisement PDF downloadLoading ...