jimnoneill/paper-to-field-training huggingface dataset:
The relationship between mindfulness and suboptimal health status: a chain/serial mediation model

Field: Psychology (Social Sciences)

Suboptimal health status (SHS) represents a third state between health and disease and often progresses into chronic conditions, negatively impacting an individual's well-being. Studies have shown that mindfulness has a beneficial effect on various SHS symptoms. This study aims to explore the influence of mindfulness on SHS and its underlying mechanisms, with a particular focus on examining the mediating roles of stress and social support.A total of 173 healthy Chinese college or graduate students, with an average age of 21.85 years, participated in this study. Measurements were taken using the Five Factor Mindfulness Questionnaire, the Sub-Health Measurement Scale, the Perceived Stress Scale, and a self-constructed scale that included demographic information. The PROCESS plugin for SPSS was used to assess mediating effects.Significant correlations were found among SHS, social support, mindfulness, and perceived stress (|r| = 0.38-0.85, p < 0.01). Specifically, mindfulness showed a significant positive correlation with SHS and social support (r = 0.38-0.77), while perceived stress was significantly negatively correlated with mindfulness, social support, and SHS (|r| = 0.45-0.85). Perceived social support was positively associated with SHS (r = 0.65). Furthermore, social support and perceived stress partially mediated the influence of mindfulness on SHS. Additionally, a sequential mediation effect of perceived social support and stress in the relationship between mindfulness and SHS was supported.The cultivation of trait mindfulness may be advantageous for individuals' sub-health. Perceived social support and perceived stress are important underlying mechanisms contributing to this effect.
Interference Effects of Fuselage-Stored Missiles on Inlet Duct Model of an Interceptor-Type Aircraft at Mach Numbers 1.5 to 1.9

Field: Engineering (Physical Sciences)

Memorandum presenting the effect of missile armament on the performance of an interceptor-type aircraft model at Mach numbers 1.5, 1.7, and 1.9 and at angles of attack up to 19 degrees. The aircraft model was characterized by triangular-shaped normal-shock inlets located at wing roots. Results regarding force measurements, effect of armament on inlet-duct performance, fuselage boundary-layer survey, and total-pressure contours at inlet throat and diffuser exit are provided.
Study on Fertility and Heterosis of Cotton Photo-thermo Sensitive Genic Male Sterile Lines

Field: Agricultural and Biological Sciences (Life Sciences)

Cotton photo-thermo-sensitive genic male sterile line(P/TGMS)was a new type of genic male sterile lines with yellow bud as marker traits,it was derived from hybrid progeny of G.hirsutum and G.barbadense.The experiment was carried out in Shijiazhuang and Sanya for the fertile alteration characteristic of P/TGMS cotton and the main ecnomic characteristics of hybrids,such as yield,disease resistance,fiber quality,salt resistance in different thermo-photoperiod conditions.The results showed that P/TGMS cotton planted in Sanya could transfer their pollen fertility from completely sterile to fertile,produce abundant pollen to increase self-fertilization ratio for reproduce naturally.However it was completely sterile in Shijiazhuang,where the selfing cotton boll rate was 0,the sterile degree was 100%,which could be used as female parent in hybrid seed production of Shijiazhuang with good combining ability,wide sterile line restoring sources and obvious heterosis.The fertility in the F1 generation of sterile hybrids could be restored,and produce abundant pollen,boll naturally and show obvious heterosis.Some hybrid combination performed high yield,better disease resistance,good fiber quality and strong salt resistance.
Equine Therapy Programs: Healthcare Organization Management

Field: Health Professions (Health Sciences)

Equine therapy programs (EAP) are currently being used as complementary therapy services. As EAP has evolved in recent years, the potential to sophisticate these programs and classify them into managed healthcare organizations is better than it's ever been. [TOPIC] Currently, EAP is standardized under the guidelines set forth by equine accrediting organizations, but no EAP center has been identified and accredited as a healthcare organization. [IDENTIFIED PROBLEM] This project provides a grant proposal and detailed business plan for an EAP called V.E.T.S. [RESULT] EAP can be successfully managed and delivered as an accessible, affordable and quality healthcare organization. [OUTCOME]
Protease-activated receptor 2 (PAR2) inhibition reduces complement-associated cardiac remodelling in obesity-related heart failure

Field: Medicine (Health Sciences)

Abstract Background and Aims Obesity is considered a major risk factor for the development of heart failure (HF) due to lipid accumulation, oxidative stress and inflammation which results in cardiac remodeling. Protease activated receptor 2 (PAR2) has been linked to various cardiovascular and inflammatory diseases. The role of PAR2 has not yet been studied in obesity-related HF. Methods In the experimental mouse study, we used 1-year-old ApoE knockout (ApoE-/-) and ApoE PAR2 double knockout (ApoE-/-PAR2-/-) mice with a C57BL/6J background on a high fat (HF) diet (n=5/ group). Cell culture experiments were performed with human primary cardiac fibroblasts and HepG2 hepatocytes. Patients (n=50) included in the clinical study had a BMI &gt; 25kg/m², symptoms of heart failure (HF), coronary angiography (CA) that excluded coronary artery disease (CAD) and endomyocardial biopsy (EMB) that confirmed the absence of active myocarditis or primary cardiac amyloidosis. Patients were divided into PAR2low (n=22) and PAR2high (n=22) based on the median PAR2 expression measured via qPCR in the EMB of the cohort, and six patients served as healthy controls. Results Evaluation of endomyocardial biopsies (EMB) from overweight/ obese non-ischemic cardiomyopathy (NICM) patients with heart failure (HF) (n=44) revealed that a reduced cardiac PAR2 expression is associated with less cardiac C3 (p≤0.054), C4 (p≤0.041) and C5 gene expression (p≤0.045), as well as plasma levels of complement C3 (1.1g/l± 0.7 vs 2.1g/l±0.2; p≤0.016) and C5b-9 (303.4ng/ml± 215.7 vs 992.7ng/ml± 756.2; p≤0.0002) and as a result, better systolic function i.e. LVEF (46.1%±17.1 vs 36.8%±15.2; p≤0.046) and LV GLS (-14.9%± 5.7 vs -9.5%± 4.6; p≤0.009), less cardiac remodeling and damage. Correspondingly, aged ApoE-/-PAR2-/-mice on a Western diet showed less hepatic and cardiac complement expression (i.e. C1q, C3, C4, C5, C9), cardiac C3 deposition (p≤0.047) and C5b-9 plasma levels (p≤0.049), as well as less cardiac necrosis (p≤0.046) and lower BNP (p≤0.016) than ApoE-/-. PAR2 overexpression in human cardiac fibroblasts (HCFs) independently enhanced and PAR2 antagonism reduced interferon γ (IFNγ)-mediated STAT1-dependent complement C3, C4 and C5 expression. Conclusions Protease-activated receptor 2 regulates complement-mediated cardiac damage and remodeling in HF. The PAR2-IFNγ/STAT1/C3-C4-C5 complement-axis might be a promising prognostic and therapeutic approach to identify and treat high-risk cases of HF in overweight/obese patients.
Stretchable and robust transistor of single wall carbon nanotube, gel and elastomeric materials

Field: Materials Science (Physical Sciences)

We have developed the coating and microfabrication technique of the single walled carbon nanotubes and its composite with rubbers in the way compatible to the conventional device technology in order to incorporate the unique properties of SWCNTs, such as diversity of electrical properties depending on the charity, mechanical flexibility and stretchability arising from the formation of network structure, with device applications. Utilizing the process technologies, we have recently succeeded in assembling the field effect transistor of all rubbery materials on the rubber substrate, demonstrating that it exhibits the transistor performance comparable to the conventional CNT-transistors and significant tolerance to the mechanical loadings. The stretchability and robustness of our FET is promising for the wearable electronics, especially which is used for human body.
Health-related quality of life among patients with cirrhosis at a tertiary care center in Addis Ababa, Ethiopia: a cross-sectional study

Field: Medicine (Health Sciences)

Background Health-related quality of life (HRQoL) reflects an individual’s perception of how disease and treatment affect their physical, functional, emotional, and social well-being. The burden of cirrhosis is high in Ethiopia but reports on HRQoL among cirrhosis patients are lacking. This study aimed to assess HRQoL and associated factors among patients with cirrhosis at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods A cross-sectional study was conducted among 221 patients with cirrhosis at Tikur Anbessa Specialized Hospital. Data were coded and entered into Epi Data 4.6.0.2 and analyzed by STATA software version 17m/p. Bivariable and multivariable linear regression analyses were performed. A p-value lower than 0.05 was used to declare statistical significance. Results The mean ± SD age was 42.74 ± 12.25. In multivariable linear regression analysis, Mid Upper Arm Circumference (MUAC) (Standardized β.coff (Std.β.coff) = 0.12, 95% CI (0.06, 0.18), age ≥50 (Std.β.coff = -0.38, 95% CI (-0.68,-0.09), Child-Turcotte-Pugh (CTP) class B (Std.β.coff = -0.92, 95% CI (-1.28, -0.55), CTP class C (Std.β.coff = -1.69, 95% CI (-2.30,-1.07) were significantly associated with mean quality of life score. Conclusion Quality of life score was significantly associated with age, CTP class, and MUAC. Health-related quality of life should be taken into consideration in the assessment and treatment of patients with cirrhosis. Older patients, patients with decompensated cirrhosis, and patients with lower MUAC measurements should be given special attention.
The Value of Integrating Nutrition in Mental Health Counseling and Treatment

Field: Psychology (Social Sciences)

Integrative Journal of Conference Proceedings The Value of Integrating Nutrition in Mental Health Counseling and Treatment Ida Chauvin*, Ewing HD and Jerry T Louisiana Tech University, Ruston, Louisiana, USA *Corresponding author: Ida Chauvin, Department of Psychology, Louisiana Tech University, Louisiana, USA Submission: January 24, 2020;Published: February 5, 2020 Volume2 Issue2February, 2020
Methodology for the Evaluation of Real Options in Real Estate Development in Areas Characterized by Uncertain Scenarios

Field: Decision Sciences (Social Sciences)

<p>The recovery of brownfield sites has been in the past and still is today at the center of urban policies that have started, set up and, in some cases, completed the main projects of urban transformation. In this regard it should be noted that large transformation areas often require a preliminary remediation before that the urban functions are established. The recovery of these areas has, among other things, the character of public interest in relation to the environmental protection and public health goals. Basically, the investment decision, concerning the development of brownfields is affected by two critical variables: the remediation costs and the market value of the area after completion of the environmental recovery. This last is in fact a complex process, which cannot be estimated with certainty, influenced by many variables, such as, for example, the cost of the single operations, the timing, the technology and the uncertainty of achieving the remediation goals (Weber et al., 2008). In the past and in many countries, the public resources were preferred to encourage the development of urban transformation projects of contaminated lands. On the contrary, the current economic scenario requires a new insight that includes the possibility of involving the private developers from the early stages of the transformation. In this regard, given the uncertainty surrounding the remediation costs, some authors (Espinoza &amp; Luccioni, 2007) have aimed to the definition of the optimal size of the investments, able to make feasible the land transformation from the financial and economic point of view, through the Real Options Theory (ROT). In this light, the work attempts to argue and support the application of the ROT, considering a contaminated area where the plan allows the change from industrial to residential and commercial use, but where the remediation costs are unavoidable. The numerical example, that is solved using the Black &amp; Scholes formula, shows that, the higher is the volatility – the uncertainty – of the transformation value of the land, more the deferral option value is increasing . After a year, the landlord will proceed with the remediation, only if the market value of the land is greater than the cost of its recovery; otherwise it will not. As a result, the payoff for the landlord is obtained from the maximization of the value added and from the sales price of the land, that, in turn, will result from the transformation value.</p>
Veterinary compounding: In vitro assessment of Methimazole-based foam for feline hyperthyroidism

Field: Veterinary (Health Sciences)

Veterinary compounding: In vitro assessment of Methimazole-based foam for feline hyperthyroidism Areej Alshikhey, Raimar Löbenberg, Michael Doschak Objective: Hyperthyroidism is one of the most common feline endocrine disorders due to excess production of active thyroid hormone in middle-aged cats. The management involves oral or transdermal antithyroid drug delivery. The use of transdermal medications in cats has become popular in veterinary medicine due to the ease of administration compared to oral medications. We hypothesized that microemulsion-based system could improve the in vitro flux of Methimazole using a Franz cell model. Method: A concentrations of 2.5% of Methimazole were incorporated into Labrafac-based microemulsion formulations with Labrasol as a surfactant and Plurol Oleique as cosurfactant to be used for transdermal delivery of Methimazole. The in vitro studies were carried out using Franz cell apparatus with a diffusional surface area of 1.79 cm2 and synthetic membranes. A direct comparison of release profiles using Franz diffusion cells between Methimazole-loaded microemulsion and commercial formulations of transdermal Methimazole were performed. Purified water was used as the receptor fluid, and the temperature maintained at 32 ± 0.5°C. The withdrawn samples were appropriately diluted and calculated at different time points 30 min, 1, 2, 4, and 6hrs using HPLC. Result: The obtained result of in vitro study indicated that the foamable microemulsion system might be a candidate carrier for transdermal delivery of Methimazole. Cumulative drug percentage releases through hydrophobic synthetic membranes into the receptor media were found to be 84.64% in Methimazole-loaded microemulsion compared to 47.86%, 33.53%, 33.08% in Lipoderm, Versapro, PLO vehicle, respectively, p< 0.05. Conclusion: Hence the microemulsion system is one of the promising tools for percutaneous delivery of Methimazole. The release profiles obtained from in vitro permeability tests might be used for predicting the in vivo permeability of the formulation. Findings from the current research work evidenced that foam-based microemulsion formulation was superior to cream-based formulations; thus, ME-based foam might be a potential vehicle for enhancing the transdermal penetration of Methimazole.
‘The fidelity of promising’: Egoism and Obligation in Austen

Field: Arts and Humanities (Social Sciences)

Abstract This essay reads the promises that permeate Sense and Sensibility (1811) in the context of late eighteenth-century discussions about the nature and value of voluntary obligations, probing Austen’s engagement with ideas advanced by thinkers including David Hume, Adam Smith, William Paley, William Godwin, and Edmund Burke. In doing so, the essay contributes to long-standing debates about Austen’s ethical vision, highlighting her simultaneous commitment to and critique of the individualist ethos structuring modern life. Austen’s approach to promises, the essay argues, is broadly aligned with that of Hume, Smith, and Paley: like these philosophers, Austen suggests that one is bound by a pledge whenever one knowingly raises another’s expectations concerning the existence of an obligation even if one does not intend to be bound. Yet Austen is less optimistic than these thinkers are about men’s willingness to honour their pledges. She uses the resources of fiction—in particular, experiments with third-person narration and point of view—to examine the problems that result from the unequal power relations between men and women as well as the tendency of individuals to conflate desire with expectation. Even as Austen attempts to shore up a sense of individual responsibility in her society, she implicitly acknowledges that, in some cases, breaking a promise may result in more happiness than keeping it would.
Peripheral blood leucocyte subpopulations in patients splenectomized for trauma.

Field: Medicine (Health Sciences)

Monoclonal antibodies were used to type leucocyte subpopulations in peripheral blood mononuclear leucocytes (MNL) from patients who had had spleens removed following trauma. The proportion of OKT3+ (T) cell and OKT4+ ('T helper/inducer') cell was significantly decreased in splenectomized subjects. While a decrease was also observed for the OKT8+ ('T suppressor/cytotoxic') cells, this was not significant. The ratio of OKT4+/OKT8+ cells was significantly decreased in the splenectomized group. Interestingly, the absolute numbers of OKT3+, OKT4+ and OKT8+ cells were increased. The % of B lymphocytes (identified as Ig+ and FMC1+ cells) was significantly increased in patients. The proportion of MHC Class II+ cells (FMC4+) was also increased although not significantly. A marked increase in % of monocytes (FMC33+) was observed in patients. The changes in proportion of regulatory T cells and monocytes may in part explain the depressed mitogen responses of MNL from splenectomized subjects.
Simultaneous Analysis Method for Polar and Non-polar Ginsenosides in Cultivated Wild Ginseng by Reversed-phase HPLC-CAD

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

산양삼은 식품 또는 약초로써 많이 사용되고 있다. 이번 연구의 목표는 high performance liquid chromatography (HPLC) - charged aerosol detection (CAD)에 의해 산양삼의 추출물에 사포닌들의 분석을 최적화 하는 것이다. CAD는 물리적인 특성은 물론이고 입자크기, 스펙트럼 특성과는 무관하게 비휘발성 물질도 분석할 수 있다. 산양삼 추출물 중 Gensenoside Rb1, Rd, Rg1, Rf, Re 및 Rh1을 분석하였다. HPLC-CAD분석을 위한 사포닌 추출물은 건조 산양삼 10 g에 95% 에탄올 100 ml을 넣어 80℃에서 24시간 동안 추출하여 사포닌을 얻었다. 6개의 주요한 사포닌을 정량화하였을 경우 값은 다음과 같다. 사포닌들의 함량은 Rb1 (5.48±0.12 mg/g), Rd (5.33±0.14 mg/g), Rg1 (12.80±0.05 mg/g), Rf (19.08±0.68 mg/g), Re (19.87± 0.05 mg/g), 및 Rh1 (16.47±0.16 mg/g)로 확인하였다. 대체적으로 산양삼 추출물의 사포닌은 protopanaxatriol (Rg1, Rf, Re, Rh1)의 값이 protopanaxadiol (Rb1, Rd)보다 높게 확인 되었다. 이번 연구에서는 산양삼 사포닌의 분석조건을 HPLC-CAD를 이용하여 최적화하였고 제품화를 위해 약리활성에 관한 연구도 매우 중요할 것이다. Cultivated wild ginseng is a widely used dietary supplement and medicinal herb. The aim of this study was to optimize the ginseng using high performance liquid chromatography (HPLC)- charged aerosol detection (CAD) for ginsenoside analysis. CAD measures the physical property of an analyte and responds to almost all non-volatile species, independent of their nature, spectral properties, or particle size. It has become widely employed in pharmaceutical analysis. The cultivated wild ginseng extracts were analyzed for compositions of ginsenosides Rb1, Rd, Rg1, Rf, Re, and Rh1. The optimal analysis condition was set up from an experiment using a gradient. Ten grams of cultivated wild ginseng were extracted with 95% EtOH 100 ml for 24 hr at 80℃. The contents of the 6six major ginsenosides in the cultivated wild ginseng extract were Rb1 (5.48±0.12 mg/g), Rd (5.33±0.14 mg/g), Rg1 (12.80± 0.05 mg/g), Rf (19.08±0.68 mg/g), Re (19.87±0.05 mg/g), and Rh1 (16.47±0.16 mg/g), respectively. HPLC showed that the protopanaxatriol group (Rg1, Rf, Re, Rh1) had more content than the protopanaxadiol group (Rb1, Rd) in cultivated wild ginseng extract. In summary, the ginsenosides were identified with HPLC-CAD analysis, and their presence and quantity imply the importance of quality control, as well as the pharmacological activity of the ginseng root.
Subjective Beliefs And Confidence When Facts Are Forgotten

Field: Psychology (Social Sciences)

Forgetting a piece of decision-relevant information is a salient source of uncertainty that should influence one's beliefs, confidence, and ambiguity attitudes. To investigate this, we run several experiments where people bet on propositions (facts) that they cannot recall with certainty. We use betting preferences to infer subjects' revealed beliefs and their revealed confidence in these beliefs. Forgetting is induced via interference tasks and time delays (up to one year). We observe a natural memory decay pattern where beliefs become less accurate and confidence is reduced as well. Moreover, we find a form of comparative ignorance where subjects are more ambiguity averse when they cannot recall the truth rather than never having learnt it. In a different vein, we identify an overconfidence pattern: on average, subjects overpay for bets on propositions that they believe in, but underpay for the opposite bets. We formulate a two-signal behavioral model of forgetting that generates all of these patterns. It suggests new testable hypotheses that are confirmed by our data.
The importance of artificial nervouses for safety of movement of road transport

Field: Engineering (Physical Sciences)

Значение искусственных неровностей для обеспечения безопасности движения автомобильного транспортаАннотация.Современное состояние безопасности движения на автомобильных дорогах нашей страны по сравнению с предыдущими годами становится более благоприятным.Однако, ужесточение правил дорожного движения и высокие штрафы за их нарушение не всегда приводят к значительному снижению смертности и ранений на автомобильных дорогах.Масштабы и характер данной проблемы по обеспечению
1 Ethnic entrepreneurship in a multicultural society

Field: Social Sciences (Social Sciences)

Modern societies are moving away from stable social and established structures toward a state of fluidity in which mobility of people (commuters, migrants) tends to become a visual landmark. The action radius of spatial mobility is steadily increasing from the local or regional scale to the national and global (Sassen, 1991; Scott, 1990). The current globalisation trend, which has only recently started, will mean an even more diffuse pattern of community life in which complex network configurations will play a dominant role. It also seems plausible that uniformity in society will increasingly be replaced by diversity, so that future societies will be characterised by their `multicolour&apos; composition, with great cultural, social, ethnic, and religious variety (Cross, 1992; Esping-Andersen, 1993; Massey and Denton, 1993; Storper, 1997). The aforementioned dynamics manifests itself in particular in cross-border migration (see Gorter et al, 1998; Nijkamp and Spiess, 1994). It should be recognised, however, that international migration as such is not a new phenomenon in many countries. In the past, we have witnessed huge transborder migration flows as a result of natural disasters, wars, famine, and poor socioeconomic conditions. Most of these movements were of a forced nature, and, in the main, caused only a temporary disturbance.With the beginning of the colonial period, the phenomenon of economic migration between countries began, sometimes forcibly supported by slavery (see, for example, Sowell, 1975). In addition, the subsequent period of the Industrial Revolution provided a further stimulus to In search of ethnic entrepreneurship opportunities in the city: a comparative policy study