MP01-13 GREENLIGHT (532 nm) LASER TRANSURETHRAL PROSTATECTOMY FOR TREATMENT OF BENIGN PROSTATE OBSTRUCTION USING XPS-180 WATT SYSTEM, DOES IT PASS THE TEST OF TIME?

Field: Medicine (Health Sciences)

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology I (MP01)1 Sep 2021MP01-13 GREENLIGHT (532 nm) LASER TRANSURETHRAL PROSTATECTOMY FOR TREATMENT OF BENIGN PROSTATE OBSTRUCTION USING XPS-180 WATT SYSTEM, DOES IT PASS THE TEST OF TIME? Fady Ghobrial, Mahmoud Laymon, Mohamed Soltan, Ahmed Abolazm, Nasr El-Tabey, and Ahmed Elshal Fady GhobrialFady Ghobrial More articles by this author , Mahmoud LaymonMahmoud Laymon More articles by this author , Mohamed SoltanMohamed Soltan More articles by this author , Ahmed AbolazmAhmed Abolazm More articles by this author , Nasr El-TabeyNasr El-Tabey More articles by this author , and Ahmed ElshalAhmed Elshal More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000001962.13AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To evaluate efficacy and durability of greenlight laser (XPS-180watt) based prostatectomy for treatment of benign prostatic obstruction (BPO). The need for medical and or surgical retreatment for recurring or residual BPO as well as their predictors will be assessed. METHODS: After IRB approval, a prospectively maintained database was established for patients with BPO for whom greenlight laser photoselective vaporization (PVP) and vapoenucleation (PVEP) of the prostate were carried out between August 2014 to March 2018. Patients’ perioperative data and urinary functional outcome parameters and postoperative complications were depicted. The need for retreatment was assessed and its predictors retreatment were evaluated. RESULTS: This study included 248 patients, 157 (63.3%) and 91(36.7%) patients underwent PVP and PVEP with mean prostate volume (60±18 and 100±22 ml) respectively. Mean ±SD follow up duration was 62±9 months. At last point follow up, mean ±SD percentage of improvement in IPSS was 61±28 and 78±20 p=0.03, median (range) percentage of improvement in Q max was 119(-13-549) and 123(-13-649) % p=0.2 and median (range) percentage of PSA reduction was 63(-172-99) and 65(-75-97) % p=0.7 for PVP and PVEP groups respectively. Overall retreatment rate (medical and surgical) was 23% (57 patients), 38 (24.2%) after PVP and 19 (20.9%) after PVEP, p=0.5. The need surgical retreatment was statistically significant more after PVP (table 1). Median (range) time to event (defined as medical or surgical re-intervention) was 20 (1-60) for all cases, 3.5 (0-42) and 30 (18-60) months p= 0.7 for PVP and PVEP groups respectively. On multivariate analysis, only percent reduction of one-year post-operative PSA was a significant predictor of need for retreatment (surgical/ medical) of recurring or residual BPO (P 0.021, 95% CI 0.018-0.024). The cutoff point was 64.2% (58.2% sensitivity, 73.4% specificity, AUC 0.647, 95% CI 0.52-0.76) above it there is less probability for having BPO retreatment. CONCLUSIONS: Greenlight laser prostatectomy using XPS-180Watt is an effective and versatile tool in treating BPO. Durability of the outcome is predictable with more postoperative PSA reduction. Source of Funding: No funding © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e5-e6 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Fady Ghobrial More articles by this author Mahmoud Laymon More articles by this author Mohamed Soltan More articles by this author Ahmed Abolazm More articles by this author Nasr El-Tabey More articles by this author Ahmed Elshal More articles by this author Expand All Advertisement PDF downloadLoading ...