jimnoneill/paper-to-field-training huggingface dataset:
Ok: A Kinetic Model for Locally Reconfigurable Molecular Systems

Field: Computer Science (Physical Sciences)

Abstract Oritatami is a formal model of RNA co-transcriptional folding, in which an RNA sequence (transcript) folds upon itself while being synthesized (transcribed) out of its DNA template. This model is simple enough for further extension and also strong enough to study computational aspects of this phenomenon. Some of the structural motifs designed for Turing universal computations in oritatami have been demonstrated approximately in-vitro recently. This model has yet to take a significant aspect of co-transcriptional folding into full account, that is, reconfiguration of molecules. Here we propose a kinetic extension of this model called the oritatami kinetic (O k ) model, similar to what kinetic tile assembly model ( k TAM) is to abstract tile assembly model ( a TAM). In this extension, local rerouting of the transcript inside a randomly chosen area of parameterized radius competes with the transcription and the folding of the nascent beads (beads are abstract monomers which are the transcription units in oritatami). We compare this extension to a simulation of oritatami in the nubot model, another reconfiguration-based molecular folding model. We show that this new extension matches better a reconfiguration model and is also faster to simulate than passing through a nubot simulation.
CYANOSIS IN INFANTS WITH NITRATES IN DRINKING WATER AS CAUSE

Field: Medicine (Health Sciences)

Five cases of idiopathic cyanosis in babies are reported. They cleared and did not recur when well water used for drinking and formula was changed, as a result of demonstrated contamination with Coliform organisms. These cases substantiate the contention of Comly that the toxic, or nitrate-containing water, is the cause of the cyanosis. This cyanosis appears as a result of the oxidation of hemoglobin into methemoglobin by the nitrites derived from nitrates present in the well water used for drinking or formula. Cyanosis cleared within a few days following removal of the infant to the hospital, away from the home water supply, but recurred within one to two weeks after returning home to the use of the contaminated water. One infant strongly suggested that milk from cows which drank the contaminated water may be the cause of moderate cyanosis when the milk supply is restricted to the single herd. One infant suggested that cyanosis may occur in a breast-fed infant, if the mother drinks the contaminated well water, or the milk from cows drinking water from that well. Many cases of cyanosis in early infancy in farm homes have been and still are being incorrectly treated for hypertrophy of the thymus gland. Cyanosis in early infancy, occurring particularly in babies living on farms one to three weeks after birth, can be cleared by using uncontaminated water.
Specific or general health outcome measures in the evaluation of total hip replacement

Field: Health Professions (Health Sciences)

We assessed 100 patients with a primary total hip replacement using the Harris hip score and the Nottingham Health Profile at one, three and five years after operation. They were derived from two prospective randomised series of cemented and uncemented replacements. Both scoring systems correlated highly and were each heavily influenced by the system of functional classification defined by Charnley. After five years both reflected the function of the implant and the general state of the patient. A higher degree of sensitivity is needed to show differences in the performance of an implant in the short and medium term. We do not yet have an ideal system of clinical assessment and the overall function must always be properly assessed.
Tacrolimus Concentration Fluctuations Caused by Chyle Leakage After Liver Transplantation: A Case Report

Field: Medicine (Health Sciences)

Background: Chyle leakage is known to be a rare postoperative complication following liver transplantation (LT), and continuously leaked large quantities of chyle leakage can worsen prognosis. However, there is no explicit understanding of its mechanism and no existing reports showing the influence of chyle leakage after LT on blood concentration of the drug tacrolimus. Case presentation: Despite escalating tacrolimus daily dose to 4.0 mg with CYP3A5 inhibitor, blood concentrations remained subtherapeutic (1.7–2.5 ng/mL) during active leakage. Conservative treatments failed, prompting intraperitoneal injection of erythromycin (0.75 g)-25% glucose solution (40 mL every other day). Following three treatments, chylous drainage diminished significantly, and tacrolimus concentrations abruptly increased to 14.7 ng/mL 2 days after leakage resolved. Dose adjustments subsequently stabilized levels at 4.6–6.2 ng/mL with daily dose of 2.0mg. Conclusions: Intraperitoneal injection of erythromycin hypertonic solution may promote lymphatic fistula closure via chemical stimulation. Chyle leakage may reduce tacrolimus blood concentration through drug loss in chylous fluid. This case highlights the need for clinical attention to the association between chyle leakage and immunosuppressant concentrations, though further studies are required for validation.
Pathology of the Testicle and Sex Accessory Glands Following the Administration of Boldenone and Boldione as Growth Promoters in Veal Calves

Field: Veterinary (Health Sciences)

FIGURE 7. Type-locality of Acratosaura spinosa sp. nov. (red star), Mucugê municipality, State of Bahia, Brazil, and distribution of Acratosaura mentalis (yellow circles) in eastern Brazil. Localities: 1. Fechados, Santana de Pirapama, MG; 2. Guinda, Diamantina, MG; 3. Peixe Cru, Turmalina, MG; 4. Cristália, MG; 5. Grão Mogol, MG; 6. Parque Nacional do Peruaçu, Januária, MG; 7. Maracás, BA; 8. Mucugê, BA; 9. Santo Inácio, Gentio do Ouro, BA; 10. Senhor do Bonfim, BA; 11. UHE de Xingo, Delmiro Gouveia, AL; 12. Serra Negra, Mata Grande, AL; 13. Serra do Triunfo, Garanhuns, PE; 14. Parque Nacional do Catimbau, Buíque, PE; 15. Brejo da Madre de Deus, PE; 16. Fazenda Bravo, Barra de São Miguel, PB; 17. Cabaceiras, PB; 18. RPPN Fazenda Almas, São José dos Cordeiros and Sumé municipalities, PB; and 19. Cacimba de Dentro, PB. For localities see Appendix, and Arzabe et al. (2005), Delfin (2007), Queiroz & Lema (1996), and Rodrigues (1986). State Abbreviations: AL = Alagoas; BA = Bahia; MG = Minas Gerais; PE = Pernambuco; PB = Paraíba.
Why didn’t it work out? The effects of attributions on the efficacy of recovery strategies

Field: Business, Management and Accounting (Social Sciences)

Purpose – The purpose of this paper is to analyze the effects of attributions on the efficacy of service recovery strategies in preventing customer defection following a service failure. Design/methodology/approach – The empirical investigation is carried out on the retail banking industry with a final sample of 448 real cases of customer retention or defection after a service failure. Findings – The results of the study not only highlight the relevance of intentionality as an additional factor in explaining customer defection, but also show the effects of some attributional dimensions (intentionality and controllability) on the efficacy of some recovery strategies (redress, apology and explanation) applied by companies to prevent post-complaint customer defection. Practical implications – The efficacy of the recovery strategies depends on the causal attributions that the customer makes about the service failure. Originality/value – This study analyzes not only the effects of traditional dimensions of attribution (stability and controllability), but also the additional effect that intentionality attributions may have on actual customer defection (not intentions). Moreover, it analyzes their effects on the effectiveness of recovery strategies in preventing customer defection. Most of these effects have never been empirically analyzed in the literature.
Non-Stationarity of Resting-State Connectivity in Patients with Brain Tumors in the Awake and Anesthetized State

Field: Neuroscience (Life Sciences)

Motivation: Map temporal fluctuations of functional connectivity (FC) in anesthetized brain tumor patients. Goal(s): Map static FC (sFC), dynamic inter-region FC (dFC), and test-retest reliability between awake and anesthetized states in patients undergoing resection of brain tumors. Approach: A sliding-window xDF method was developed to estimate variance of the correlation in spatial-temporal resolution resting-state fMRI, considering nonstationary autocorrelation and cross-correlation. Results: The largest decrease in sFC during anesthesia was observed across, rather than within, networks. The sliding-window xDF increased sensitivity compared to the static model. Test-retest reliability between cortical areas was higher during anesthesia versus awake state, in contrast to subcortical and cortical-subcortical dFC. Impact: These results demonstrate the feasibility of performing resting-state functional connectivity studies in intraoperative settings with high spatial-temporal resolution. The higher test-retest reliability within cortical areas during anesthesia versus awake state informs the design of minimum duration intra-operative resting-state fMRI protocols.
Determining the Relationship between Lower Limbs Strength Parameters and Balance in 5-8-Year-Old Children Practicing Dance

Field: Health Professions (Health Sciences)

This paper aims to determine the relationship between parameters of lower limb strength and balance in 5-8-year-old children practicing dance. Methods. So, an exploratory study was organized with a group of 24 children aged 5-8 years from the National Palace of Children of Bucharest. Tests used: Test 1 (15 jumps free arms), Test 2 - static balance (SB), Test 3 – lateral dynamic balance (LDB) and Test 4 vertical dynamic balances (VDB). Parameters: performance, front and back inside (LDB), left and right inside (VDB), avg. deviation. In this regard, establishing the relationship degree between lower limb strength parameters and balance in 5-8-year-old dancers depends on the number of negative correlations, especially between average deviation parameters.
Discovery and Total Synthesis of Streptoaminals: Antimicrobial [5,5]‐Spirohemiaminals from the Combined‐Culture of Streptomyces nigrescens and Tsukamurella pulmonis

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract A series of lipidic spirohemiaminals, designated streptoaminals, is reported. These were discovered by surveying the unique molecular signatures identified in the mass spectrometry data of the combined‐culture broth of Streptomyces nigrescens HEK616 and Tsukamurella pulmonis TP‐B0596. Mass spectrometry analysis showed that streptoaminals appeared as a cluster of ion peaks, which were separated by 14 mass unit intervals, implying the presence of alkyl chains of different lengths. The chemical structures of these compounds were elucidated by spectroscopic analysis and total synthesis. Streptoaminals with globular structures showed broad antimicrobial activities, whereas the planar structures of the 5‐alkyl‐1,2,3,4‐tetrahydroquinolines found in the same combined‐culture did not. This work shows the application of microbes as reservoirs for a range of chemical scaffolds.
Tara Alberts. Conflicts and Conversion: Catholicism in Southeast Asia, 1500–1700.

Field: Arts and Humanities (Social Sciences)

Tara Alberts has written an excellent and ambitious book on the early history of Catholicism in Southeast Asia. It is ambitious in both the scope of the cultures studied and in the complexity of the subject matter. It is to Alberts's credit that she manages to hold these countries and challenges together with the lightest of touches as she leads the reader through otherwise confusing terrain. In her introduction Alberts presents the three “hows” of the missionary endeavor she wishes to explore. First, how did successive generations of missionaries respond to the evocative accounts of martyrdom and evangelization regularly communicated back to Europe in such propagandistic publications as Giovanni Filippo di Marini's Historia et relatione del Tunchino e del Giappone (1665) or the Lettres édifiantes et curieuses series (first published in 1702)? Second, how do scholars examine hitherto little-used archival resources to understand why some Southeast Asians converted while others not only did not, but also actively opposed Christian presence (the “conflict” of her title)? And third, how were lay Christians in this diverse region able to exercise their agency and even reshape Catholicism such that it ceased to be a European import and became a religion both localized and international?
Data from Oropharyngeal Cancer, Race, and the Human Papillomavirus

Field: Medicine (Health Sciences)

<div>Abstract<p>This perspective on Settle et al. (beginning on p. 776 in this issue of the journal) discusses the racial disparity in oropharyngeal cancer survival in relation to the biological factor human papillomavirus and its association with sexual behavior. This discussion is expanded to a more general consideration of biological and nonbiological (e.g., socioeconomic and cultural) factors affecting racial disparities in disease.</p></div>
The Normative Broken: Melinda Gebbie, Feminist Comix, and Child Sexuality Temporalities

Field: Arts and Humanities (Social Sciences)

Abstract Lost Girls (2006) is a return to the themes explored by Melinda Gebbie and other underground feminist cartoonists in the 1970s and 1980s. The text, a collaboration between Gebbie and Alan Moore, should be read as reminiscent of feminist cartoonists who intentionally depicted the taboo or obscene in order to address sexual and gender inequalities. These comics suggest that the obscene can push against purity narratives attached to womanhood, narratives that potentially stigmatize all girls and women. Lost Girls keeps the taboos of children’s sexuality and incest central to the representation in order to reframe possibilities of women’s healthy sexual subjectivity. Injurious pasts and irreconcilable desires do not preclude joyous futures. Painful pasts enable the eponymous lost girls’ agency, creating the conditions that help them find homosocial and queer belonging with one another. The comic thus models the temporalities of surviving trauma. The feminist temporalities of survivorship here also model utopian futures that are homosocial, queer, often ecstatic, and resistant to normative scripts of what should give women comfort. Undergirded by a radical feminist perspective that sees injury as being embedded in many women’s experiences, the creation of community from the wound makes it normal to have been broken.
The MeerTime Thousand Pulsar Array: Elucidating the population properties of neutron stars

Field: Physics and Astronomy (Physical Sciences)

The long-term timing of radio pulsars yields a rich vein of science. The Thousand Pulsar Array (TPA) programme uses the power of MeerKAT in sub-array mode to monitor and time more than 500 pulsars with a monthly cadence. This allows us to explore the turbulent, magnetic structure of the interstellar medium through the time-variability of the dispersion and rotation measures. More importantly it sheds light on the spin-down history of these pulsars and the correlation between changes in the torque and observed radio profile shapes. Understanding this behaviour is a critical component in the detection of gravitational waves through pulsar timing arrays. In this talk I will introduce the TPA long-term monitoring programme, provide an overview of the current project status and describe key science results, including measurements of pulsar viewing and magnetic geometries, assessing the stability of pulsar spin-down rates with time, and an observationally driven unification of the bulk properties of young and millisecond pulsars.
Silicon Application to Several Soybean (Glycine max, Merrill) Varieties Under Drought Stress Condition

Field: Agricultural and Biological Sciences (Life Sciences)

Drought stress becomes a serious threat to the cultivation of soybean because it could affect the whole processes of soybean plants that may ultimately result in a significant reduction in yield. To obtain high production in drought stress conditions, one needs such efforts as including the use of utilizing high yielding varieties resistant to drought and/or designing environmental alteration engineering by using compounds or substances which can set osmolitic regulation. This study aims to determine the effect of the use of silicon (silica) on the four morpho-agronomic characters of soybean varieties tested. The study is designed by using a Factorial Randomized Block Design basis and implemented at the Faculty of Agriculture experiment station UPN “Veteran” Jawa Timur. The results showed that there were are significant interactions between treatment varieties and silica concentration for of the variables; the number of branches, number of pods per plant, and seed weight per plant. Character of each variety show varied responses to the application of silicon. Silicon concentration of 20 cc / l increased the weight of seed weight per plant and seed yield potential per hectare.
An Interdisciplinary and Empirical View of Literary Education: Using Original and Translated Poetry in the Classroom

Field: Arts and Humanities (Social Sciences)

Historically, literary research has prioritized hermeneutic interpretations over empirical approaches. Despite a few efforts to examine real readers’ emotional responses (e.g., Fialho, Miall, and Zyngier 2012; Zhang and Lauer 2015; Hakemulder et al. 2016; Miall and Chard 2016), investigations in the area of literary education have privileged theoretical discussions rather than looking at student-readers’ reactions. The chapter argues that, besides examining students’ reactions, cultural differences also come into play when reading in a foreign language, so they must be taken into account. Based on empirical evidence derived from a large-scale project involving three national groups – Brazil, Ukraine and the US – and four languages – English, Portuguese, Russian and Ukrainian (Chesnokova et al. 2009; Chesnokova et al. 2017), in this chapter we report briefly the results of how 995 participants (all university students of the Humanities from both private and public sectors in urban areas) responded to poems by Poe in the source text or in translation into their native languages. The participants from Kiev and Rio de Janeiro learned English as a foreign language. The North American respondents were undergraduate students from Portland, Oregon, majoring in English, History and the Humanities. We argue that the differences that surged in these studies cannot be overlooked especially when decisions are taken on what language the texts used in the classroom will be made available to the students. From a pedagogical perspective, this chapter aims at casting light on the intercultural implications involved when reading literary texts in original and translated versions and offers active learning strategies that may promote collaborative interactions in courses where literary interpretations are considered. It is true that when properly contextualized and discussed, texts from different countries, even when translated, may help students become more sensitized to cultural differences. In this paper, we present empirical data that enable us to state that, instead of following a traditional hermeneutic approach or discussing facts that a wide variety of texts may offer, the perception of how language works in translated texts may promote insights from other peoples and other world views.
Migrating emboli of retinal arteries in thrombocythaemia.

Field: Medicine (Health Sciences)

Case reportA 37-year-old man, in the early months of I 965 complained of repeated attacks of temporary blind- ness in the right eye, occurring on an average of three or four times a week, and lasting for 2 to 3 minutes. HistoryThe patient had had two cerebral concussions in I952 and in 1955.In 1958 he had a slight attack and in April, I964, a more serious attack of aphasia.The neurological diagnosis was syndrome of the temporal lobe with aphasia, probably of vascular aetiology.The visual acuity at this time was normal.On fundus examination a small white stripe was seen along the upper temporal branch of the right central retinal artery some 2 disc diameters from the edge of the papilla.This phenomenon was considered to be an arteriolar spasm.The surrounding retina showed an area of slight oedema I disc diameter in size.The patient had no symptoms.The oedema of the retina disappeared after 2 minutes as did the white stripe and the fundus became normal in appearance.Other clinical examinations were negative except for the neurological findings which consisted of the residue of expressive aphasia. ExaminationAfter discharge from hospital episodes of misty vision in the right eye occurred with greater fre- quency and the patient was re-admitted in December, I965, when a photograph was taken of a spasm, this time progressing from the papilla to where the blood vessel divided into three branches above the papilla.This spasm remained visible for about half a minute (Fig. i) and at the same time N FIG.I Two emboli are seen, one at the bifurcation of the retinal artery, the other more distally
Design and characterization of fast dissolving buccal film of imipramine HCL

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

In depressed individuals, Imipramine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. Imipramine hydrochloride having variable bioavailability i.e. ranging from 29-77% due to first pass metabolism, peak plasma concentration is usually attained 2-6 hours. Absorption is unaffected by food. It is freely soluble in water. The objective of this research work is to improve the bioavailability of the drug and fast the onset of action to decrease the depressant activity. The Buccal bioavailability of Imipramine HCL is only 29-77% for this reason drug can be administered into Buccal mucosa using mucoadhesive film. It can be made fast drug release and directly enter into blood circulation through Buccal mucosa and increase the drug bioavailability. Fast dissolving Buccal films were prepared by solvent casting method using various polymers like hydroxyl propyl methyl cellulose E15, PVP, PVA and sodium saccharin, plasticizer and vanillin as flavouring agent. Dissolution profile as studied in USP dissolution apparatus type 1 using pH 6.8 simulated saliva. The influence of variable like polymer type and concentration on Imipramine HCL release profile was studied. The formulation was optimized on the basis of various evaluation parameters like drug content and in vitro drug release. Formulation F3 successfully fast the release of drug within 8 minutes. The IR Spectra revealed the absence of interaction between drug and selected polymer, results of stability studies were as per ICH guide lines and results indicated that the selected formulation was stable.
Monitoring and forecasting of Dendrolimus punctatus by sex pheromone lure

Field: Agricultural and Biological Sciences (Life Sciences)

The test on trapping adult Dendrolimus punctatus by synthetic sex pheromone lure and monitoring of larval population density in forest was conducted.The result showed that,with low population density of larva(below 100 per plant) and low trapping number of adult(below 65),the trapping number of adult had significantly correlation with the population density of larva,which could be simulated by power function equation 1n(T)=2.278×1n(p)-2.521.With high population density of larva and high trapping number of adult,the trapping number of adult had no obvious correlation with the population density of larva.