jimnoneill/paper-to-field-training huggingface dataset:
Assessment of Clinical Outcomes Following Ankle Arthro desis Among Patients Who Had Post Traumatic Arthritis and Infected Primary Ankle Injury at Specialized Hospitals in Kaduna, Kaduna State, Nigeria

Field: Medicine (Health Sciences)

This study is on the assessment of clinical outcomes following ankle arthrodesis among patients who had posttraumatic osteoarthritis of the ankle and infected open primary ankle injury at specialized hospitals in Kaduna, Kaduna State, Nigeria, with the aim of determining the mechanism of injury, mode of treatment and treatment outcome. A retrospective study research design was employed for all the patients to collect data from the two specialized hospital records. The data were analyzed using Pearson and chi-square test tool. The results revealed that Motor vehicular crashes (MVCs) are the leading mechanism of injury, accounting for 66.7%, majority of patients underwent ankle arthrodesis using Charnley’s compression clamp, and on the functional outcomes measured using the AOFAS Ankle-Hind foot scale, findings show that they were favorable, with over 80% of patients achieving good-to-excellent results. The paper recommended that further research with larger cohorts and randomized controlled designs is warranted to more definitively compare the long-term efficacy and safety profiles of Charnley’s clamp versus trans articular screw fixation in ankle arthrodesis.
Colocalization of synaptophysin with transferrin receptors: implications for synaptic vesicle biogenesis.

Field: Neuroscience (Life Sciences)

We have reported previously that the synaptic vesicle (SV) protein synaptophysin, when expressed in fibroblastic CHO cells, accumulates in a population of recycling microvesicles. Based on preliminary immunofluorescence observations, we had suggested that synaptophysin is targeted to the preexisting population of microvesicles that recycle transferrin (Johnston, P. A., P. L. Cameron, H. Stukenbrok, R. Jahn, P. De Camilli, and T. C. Südhof. 1989. EMBO (Eur. Mol. Biol. Organ.) J. 8:2863-2872). In contrast to our results, another group reported that expression of synaptophysin in cells which normally do not express SV proteins results in the generation of a novel population of microvesicles (Leube, R. E., B. Wiedenmann, and W. W. Franke. 1989. Cell. 59:433-446). We report here a series of morphological and biochemical studies conclusively demonstrating that synaptophysin and transferrin receptors are indeed colocalized on the same vesicles in transfected CHO cells. These observations prompted us to investigate whether an overlap between the distribution of the two proteins also occurs in endocrine cell lines that endogenously express synaptophysin and other SV proteins. We have found that endocrine cell lines contain two pools of membranes positive for synaptophysin and other SV proteins. One of the two pools also contains transferrin receptors and migrates faster during velocity centrifugation. The other pool is devoid of transferrin receptors and corresponds to vesicles with the same sedimentation characteristics as SVs. These findings suggest that in transfected CHO cells and in endocrine cell lines, synaptophysin follows the same endocytic pathway as transferrin receptors but that in endocrine cells, at some point along this pathway, synaptophysin is sorted away from the recycling receptors into a specialized vesicle population. Finally, using immunofluorescent analyses, we found an overlap between the distribution of synaptophysin and transferrin receptors in the dendrites of hippocampal neurons in primary cultures before synapse formation. Axons were enriched in synaptophysin immunoreactivity but did not contain detectable levels of transferrin receptor immunoreactivity. These results suggest that SVs may have evolved from, as well as coexist with, a constitutively recycling vesicular organelle found in all cells.
Terrestrial planet finder: technology development plans and progress

Field: Physics and Astronomy (Physical Sciences)

One of humanity's oldest questions is whether life exists elsewhere in the Universe. The Terrestrial Planet Finder (TPF) mission can survey stars in our stellar neighborhood to search for planets and perform spectroscopic measurements to identify potential biomarkers in their atmospheres. TPF is planned for launch around 2015. Two major classes of mission have been identified as likely to meet the TPF goals: visible-light coronagraphs, and infrared interferometers. Within the interferometer class are options for using separated spacecraft or a connected structure. TPF is in the midst of an intensive period of technology development, design study, and scientific investigation to make a selection in 2006 for Phase A development. Substantial funding has been committed for development in these three areas, with the largest portion going to support demonstration of key technologies. Efforts underway through industry and university contracts and at JPL include a number of system and subsystem testbeds, as well as components and numerical modeling capabilities. The science, technology, and design efforts are closely coupled to ensure that requirements and capabilities are consistent and meet the science goals.
Corpuscular influences upon the upper atmosphere

Field: Physics and Astronomy (Physical Sciences)

The evidence for the corpuscular theory of magnetic storms and aurorae is briefly reviewed. No certain success has attended the efforts made to detect the solar corpuscles during their emission from the sun or their passage to the earth; recent observations of atomic hydrogen lines in the auroral spectrum, which are broadened and displaced by Doppler effect, give the most direct support yet available to the corpuscular theory.
Time Imagery, Introversion and Fantasied Preoccupation in Simulated Isolation

Field: Psychology (Social Sciences)

The propensity to view time in passive-oceanic images is shown to be positively correlated with introversive tendencies as manifest on the Myers-Briggs Type Indicator and with preoccupation with moral and rational discipline under conditions of extreme hypothetical personal isolation. The existence of this three-fold syndrome is seen as related to the character and orientation of the ego structure, manifesting itself in three separate but highly correlated ways.
Intelligent malay speech therapy system

Field: Health Professions (Health Sciences)

This study describes the design of an intelligent computer based Malay speech therapy system for Malay vowels. The proposed system is very convenience for the patient can undergo therapy like they are speaking naturally. The target patient group is Malay children therefore the system is created based on male and female children from 7 to 12 years old. Multi layer Perceptron is used as a method of speech recognition in proposed system. The speech therapist can easily use this system to perform therapy on children with speaking difficulty and speech disorder. By adding video of the training speaker and Magnetic Resonance Image, the children would be able to observe the correct way of articulating and pronouncing of different vowels. Moreover, children are able to practice and test on their own time independently and recognition system can evaluate their pronouncing.
Effect of Crude Aqueous Extract of the Leaf of Cissampellos Owariences on Litter Number in Rats

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective: To determine the effect of a crude aqueous extract of the leaf of Cissampellos Owariences on the number of Litters produce per rat against the background of a folkloric reputation an application to human patients.
Method: The method for extraction included the use of cold percolation and distilled water. The extract was administered to mature albino rats of proven fertility using the orogastric method.
Main outcome measure: Litter number Results: The extract significantly reduced the number of litters produced by the rat.
Conclusion: Cissampellos Owriences has a deleterious effect on the reproductive system and caution must be exercised in its use in humans. Key Words: Crude aqueous extract, Cissampellos Owariences, Litter number. Jnl of Medical Investigation and Practice Vol.1 2000: 35-40
Factors Associated with Specialist Referral for Patients with Type 2 Diabetes in Southwestern and Central Ontario

Field: Medicine (Health Sciences)

Objective: Determine the referral rate and the visit and patient factors associated with specialist referral for patients with type 2 diabetes. Methods: Sample consisted of 9,443 patient-physician visits from eight family practice groups in southwestern and central Ontario. GEE was used for the regression analysis. Results: The referral rate was 3.7 referrals per 100 patient visits. The odds of referral decreased if a visit occurred with a female patient and if an ACR measurement was not available at the visit. A one year increase in the number of years with the family physician resulted in a lower odds of referral. The odds of referral increased if the patient had a specialist appointment in the previous two years, if lifestyle counseling occurred and if a neuropathy examination was performed. Conclusions: Further research should assess the influence of visit level factors on decision making. Guidelines for specialist referral should also be considered.
An Assessment of Pre-Primary School Programme Activities in Kwara State, Nigeria

Field: Social Sciences (Social Sciences)

In National Policy on Nigerian Education (NPE, 2004) Pre-primary education or early childhood education is a process of educating young children in educational institutions prior to their entry into primary schools. This study assesses Pre-primary schools programme activities across Kwara State, Nigeria. The objective is to determine the extent to which the programme on the ground has met with the stipulated policy statement as contained in the National Policy on Education. The findings revealed the jeopardy due to: the lack of government adherence to the objectives of the policy in respect of adequate funding, infrastructural development, material and non – material resources and standard curriculum guidelines as stipulated in the policy statement. The findings in this study would thus serve as a yardstick for success or otherwise of the policy statement as contained in the National Policy on Pre-primary education which would serve in facilitating actions toward improving Pre-primary education in Kwara State and in Nigeria in general. Keywords: Policy statement, Pre-primary Education, National policy, Assessment, Educational Administration, School Programme, Curriculum, Instructional Material
Credit derivatives: where will they go from here?

Field: Economics, Econometrics and Finance (Social Sciences)

Describes credit derivatives (CDs) and the beginning and meaning of this market with strengths and weaknesses. Wonders who should care most about CDs and gives the following examples: insurance companies; corporations; investors; and banks, giving full details of all, and stresses CDs make natural business sense for these users. Projects that CDs in an investment bank could fit in either of the areas of derivatives – fixed income and credit – and it could also fit in areas such as: mortgages; mergers and acquisitions – or project finance. Closes by stating that CDs are here to stay.
The Evaluation of Multiple Birth Rates For Patients Who Had IVF-ET Procedure in Our Clinic

Field: Medicine (Health Sciences)

OBJECTIVE: We evaluated the multiple birth rates for the patients who had undergone IVF-ET procedure in our clinic. STUDY DESIGN: Total number of births and the amount of the births following assisted reproductive techniques (ART) in 2006 in Gulhane Military Medical Academy was investigated. We determined the multiple pregnancy rates among the total births, and our overall success rates, and compared those with the embryo transfer policies and the multiple pregnancy rates of other countries. RESULTS: 120 out of 1797 births (6.6%) in 2006 was the result of ART. A total of 345 embryo transfers made resulted in 176 pregnancies (51%). Live birth rate per embryo transfer was 35%, (120/345). Multiple births were 42 (2.5%), and all were the result of the ART. The ratio of multiples in ART pregnancies were 35%, (42/120). CONCLUSION: Elective single embryo transfer should be promoted by explaining the patients the possible complications of the multiple pregnancies in detail.
Gianotti-Crosti Syndrome in an Adult after Influenza Virus Vaccination

Field: Medicine (Health Sciences)

have had Sjogren's syndrome.Such patients, in whom the cause of lip licking can be iden tified, are older at onset.The age in our patient is atypical of idiopathic lip licking.The clinical findings in the reported cases included dryness with scales of the perioral area, an annular dark red rash that was clearly marginated, greater severity of the lesion in the peripheral region and around the lower lip, normal skin adjacent to the vermilion bor der and, in some cases, fissure, pigmentation and inflammation.The lesion in lip licking can be differen tially diagnosed from eczema periorale.bc-
Target normal sheath acceleration: theory, comparison with experiments and future perspectives

Field: Physics and Astronomy (Physical Sciences)

Ions can be effectively accelerated during the interaction of an ultra-intense ultra-short laser pulse irradiating a thin solid target via the so-called target normal sheath acceleration (TNSA) mechanism. One of the pivotal questions at this stage of the research is how to predict the properties of the accelerated ions, both from a fundamental point of view and in the light of foreseen applications. In this context, it is desirable to have a simple but reliable description to be used to extrapolate current results to future regimes, which will be made available in the near future, thanks to developments in laser technology. In this paper, the possible approaches for an analytical description of TNSA are discussed, and a theoretical TNSA model is developed. This model is then used to investigate the maximum ion energy as a function of laser parameters. Detailed comparisons with available experimental data and scaling laws are presented. In particular, the relative role played by both the laser pulse energy and irradiance in determining the ion features is investigated.
Oldman Lake ostracode surface sample dataset

Field: Earth and Planetary Sciences (Physical Sciences)

Raw data for the Oldman Lake ostracode surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
The Effect of Methadone-Maintenance Therapy with and Without Interactive Treatment on Improving Emotion-Regulation Strategies and Resilience Among Opiate-Dependent Clients

Field: Psychology (Social Sciences)

Due to the chronic and recurrent nature of addiction, many people who quit drug addiction may slip back into the pattern of using drugs shortly after the detoxification period. Emotion-regulation strategies and resilience play an important role in preventing the recurrences of substance abuse.This study aimed to compare the effects of methadone-maintenance therapy (MMT) and interactive therapy (a combination of MMT and cognitive-behavioral therapy) on improving emotion-regulation strategies and resilience among opiate-dependent clients.This pretest-posttest quasi-experimental study was performed on 60 patients with substance abuse admitted to Methadone Addiction Treatment Centers and Detox Centers in Sari within three months of therapy for their addiction (from October to December 2013). Then, the participants were randomly assigned to two different groups (n = 30) were examined in two groups of 30 people targeted to be available in the selected population. Participants in all three groups, before and after the intervention, filled out the questionnaires of Schutte emotional intelligence scale and Connor-Davidson resiliency questionnaire. Data were analyzed using the analysis of covariance method.The results showed that an interactive therapy would be significantly more effective than the MMT on improving emotion-regulation strategies and promoting the resilience level among opiate-dependent clients. Moreover, the results showed that cognitive- behavior therapy combined with MMT may improve emotion-regulation strategies, and promote the amount of resiliency and recovery.The cognitive-behavior therapy combined with MMT can improve emotion-regulation strategies and resiliency and thus prevent the substance-abuse relapse.
Gender Diversity of Corporate Boards and Key Financial Metrics

Field: Business, Management and Accounting (Social Sciences)

Gender diversity has been a topic of debate for some time. While males have dominated corporate boards for a long time, women are slowly making their way to the top echelons of the corporate world. Proponents of gender diversity suggest that women are able to bring a unique perspective to the board table especially since they are gaining experience at all levels. A survey on global trends in board diversity confirms a steady, albeit incremental, increase in female board membership. In this study, we compare key financial performance metrics of companies with gender diversity on boards with those that have no women on boards. Results show a significant difference between the two groups: companies with gender diversity on boards perform better than those that lack diversity.Â An important question remains, however: does diversity contribute to success or success invite diversity.
First ALMA observations of the HD 105211 debris disc: A warm dust component close to a gigayear-old star

Field: Physics and Astronomy (Physical Sciences)

Most debris discs consist of a gas-poor, cold dust belt located tens to hundreds of astronomical units away from the host star. Many cold dust belts exhibit distinct structures attributed to the dynamic interaction of planetary systems. Moreover, in a few systems, additional warm components can be found closer to the central star, resembling the asteroid belt or zodiacal dust in our Solar System. In this work, we investigate the structure of the disc surrounding the nearby F2V star HD 105211, which has a warm excess and a potential asymmetry in the cold belt. We applied the CASA pipeline to obtain the ALMA 1.3 mm continuum images. Then we constructed the SED and performed MCMC simulations to fit a model to the ALMA visibility data. To characterise the disc asymmetry, we analysed the ALMA images of two individual observation blocks and compared them to the previous Herschel images. Our modelling reveals that the disc is a narrow ring (23.6+-4.6 au) with low eccentricity positioned at a distance of 133.7+-1.6 au from the central star, which differs from the broad disc (100+-20 au) starting at an inner edge of 87+-2.5 au, inferred from the Herschel images. We found that both observation blocks show excess emission at the stellar position, while OB1 shows an offset between the star and the phase centre, and OB2 shows brightness clumps. We used a two-temperature model to fit the infrared SED and used the ALMA detection to constrain the warm component to a nearly pure blackbody model. The relatively low ratio of actual radius to blackbody radius of the HD105211 debris disc indicates that this system is depleted in small grains, which could indicate that it is dynamically cold. The excess emission from the stellar position suggests that there should be a warm mm-sized dust component close to the star, for which we suggest two possible origins: in situ asteroid belt or comet delivery.
Real world data in mechanical thrombectomy: who are we losing to follow-up?

Field: Medicine (Health Sciences)

Background Missing outcome data (MOD) is a common problem in clinical trials and registries, and a potential bias when drawing conclusions from these data. Identifying factors associated with MOD may help to increase follow-up rates and assess the need for imputation strategies. We investigated MOD in a multicenter, prospective registry study of mechanical thrombectomy (MT) in large vessel occlusion ischemic stroke. Methods 13 082 patients enrolled in the German Stroke Registry-Endovascular Treatment from May 2015 to December 2021 were analyzed with regard to MOD (90 day modified Rankin Scale, mRS). Univariate logistic regression analyses identified factors unbalanced between patients with and without MOD. Subgroup analyses were performed to identify patients for whom increased efforts to perform clinical follow-up after hospital discharge are needed. Results We identified 19.7% (2580/13 082) of patients with MOD at the 90 day follow-up. MOD was more common with higher pre-stroke disability (mRS 3–5, 32.2% vs mRS 0–2, 13.7%; P<0.001), absence of bridging intravenous thrombolysis, longer time to treatment, and in patients with high post-stroke disability at discharge (mRS 3–5 vs 0–2: OR 1.234 (95% CI 1.107 to 1.375); P<0.001). In contrast, MOD was less common with futile recanalization (thrombolysis in cerebral infarction (TICI) score of 0–2a, 12.4% vs TICI 2b–3, 15.0%; P=0.001). In patients discharged alive with well documented baseline characteristics, shorter hospital stay (OR 0.992 (95% CI 0.985 to 0.998); P=0.010) and discharge to institutional care or hospital (OR 1.754 (95% CI 1.558 to 1.976); P<0.001) were associated with MOD. Conclusion MOD in routine care MT registry data was not random. Increased efforts to perform clinical follow-up are needed, especially in the case of higher pre-stroke and post-stroke disability and discharge to hospital or institutional care. Trial registration NCT03356392 .