jimnoneill/paper-to-field-training huggingface dataset:
Inertial migration of a neutrally buoyant spheroid in plane Poiseuille flow

Field: Physics and Astronomy (Physical Sciences)

We study the cross-stream inertial migration of a torque-free neutrally buoyant spheroid, of an arbitrary aspect ratio $κ$, in wall-bounded plane Poiseuille flow for small particle Reynolds numbers\,($Re_p\ll1$) and confinement ratios\,($λ\ll1$), with the channel Reynolds number, $Re_c = Re_p/λ^2$, assumed to be arbitrary; here, $λ=L/H$ where $L$ is the semi-major axis of the spheroid and $H$ denotes the separation between the channel walls. In the Stokes limit\,($Re_p =0)$ and for $λ\ll 1$, a spheroid rotates along any of an infinite number of Jeffery orbits parameterized by an orbit constant $C$, while translating with a time dependent speed along a given ambient streamline. Weak inertial effects stabilize either the spinning\,($C=0$) or the tumbling orbit\,($C=\infty$), or both, depending on $κ$. The separation of the Jeffery-rotation and orbital drift time scales, from that associated with cross-stream migration, implies that the latter occurs due to a Jeffery-averaged lift velocity. Although the magnitude of this averaged lift velocity depends on $κ$ and $C$, the shape of the lift profiles are identical to those for a sphere, regardless of $Re_c$. In particular, the equilibrium positions for a spheroid remain identical to the classical Segre-Silberberg ones for a sphere, starting off at a distance of about $0.6(H/2)$ from the channel centerline for small $Re_c$, and migrating wallward with increasing $Re_c$. For spheroids with $κ\sim O(1)$, the Jeffery-averaged analysis is valid for $Re_p\ll1$; for extreme aspect ratio spheroids, the regime of validity becomes more restrictive being given by $Re_p\,κ/\ln κ\ll 1$ and $Re_p/κ^2 \ll 1$ for $κ\rightarrow \infty$\,(slender fibers) and $κ\rightarrow 0$\,(flat disks), respectively.
LMD-17. Neoplastic meningitis in lung cancer: retrospective review of clinical features, diagnosis and outcome in adult patients

Field: Medicine (Health Sciences)

Abstract Background Neoplastic Meningitis (NM) is a lethal complication of cancer. Its incidence is rising and in 10% of the cases NM is the first manifestation of the disease. Diagnosis relies on the clinical manifestations, neuroimages, and finding of malignant cells in cerebrospinal fluid (CSF). Diagnosis is often challenging due to the low sensitivity of the different diagnostic modalities. The aim of this study is to identify the clinical features, diagnosis, treatment and outcome of lung cancer patients with NM. Methods Clinical records from patients with diagnosis of lung cancer and NM between 2011–2021 were retrospectively reviewed at a tertiary neurological center in Buenos Aires, Argentina. Results Twenty-seven patients were included. Median age was 58 years (IQR 52–64). 17 (65%) were female. Twenty-four patients had non-small cell lung cancer (91% adenocarcinoma), two had neuroendocrine lung cancer and one small cell lung cancer. In 19 (70%), meningeal involvement was a result of progressive disease from previously diagnosed cancer. In 12 (44%) patients meningeal disease developed posterior to parenchymal brain metastases surgical approach, 5 (41%) with posterior fossa craniotomy. Headache was the most frequent symptom (53%). CSF analysis was abnormal in 13 (48%) patients, with positive cytology in 10 (37%). Meningeal enhancement was detected with magnetic resonance imaging of brain or spine in 24 (92%) patients. Twenty-one (77%) patients received oncological treatment, 14 (51%) with chemotherapy (8 systemic, 3 intrathecal and 3 intrathecal plus systemic). Thirteen (48%) patients underwent treatment with either immunotherapy or target-therapy. 11 patients underwent whole brain radiotherapy. Median overall survival was 7 months (CI 95%: 3.5–10.4). Conclusion Headache was the most frequent symptom. Ninety-two percent of patients had meningeal pathological enhancement in high-quality MRI with gadolinium contrast of brain and spine. Despite median survival was poor (7 months), small subsets of these patients (22%) survived more than 2 years.
Private Finance Initiative in the healthcare sector: trends and risk assessment

Field: Business, Management and Accounting (Social Sciences)

Purpose The UK Government has now adopted Private Finance Initiative (PFI) as a major vehicle for the delivery of additional resources to the health sector in order to achieve a greater investment in healthcare facilities. The purpose of this paper is to examine the trends and risk assessment of the PFI in the healthcare sector. Design/methodology/approach The paper employed secondary data and interviews of key participants in two hospital PFI projects to highlight developments in healthcare PFI and the risk management of hospital projects. Findings The results show that the use of PFI in the provision of healthcare is increasing in terms of number, capital value and size of projects. What emerged in the healthcare PFI project was a usage of a plethora of risk management techniques, albeit to varying degrees. Experience appeared to be the prime risk assessment technique employed, while risk avoidance was first explored before pricing and allocating any residual risks. “Risk prompts”, such as using checklists and risk registers were also useful in the identification of risks. Among all participants, insurance cover and sub‐contracting appear to be the most prominent strategies employed for managing out the risks. Originality/value The negotiations that precede the signing of a healthcare PFI project contract had an impact on the final choice of facilities or their specifications. The two contracting parties sought a balance between an optimal allocation of risks, choice of facilities and project price. Although the risk management techniques being used are generic in nature, there is still no evidence at the moment to show that these are appropriate for PFI projects. It is important that further investigation is undertaken to assess the level of current skills in risk management techniques to deal with PFI projects and the extent to which these techniques are appropriate to tackle complex healthcare PFI projects.
Processing of Sound Sequences in Macaque Auditory Cortex: Response Enhancement

Field: Neuroscience (Life Sciences)

It is well established that the tone-evoked response of neurons in auditory cortex can be attenuated if another tone is presented several hundred milliseconds before. The present study explores in detail a complementary phenomenon in which the tone-evoked response is enhanced by a preceding tone. Action potentials from multiunit groups and single units were recorded from primary and caudomedial auditory cortical fields in lightly anesthetized macaque monkeys. Stimuli were two suprathreshold tones of 100-ms duration, presented in succession. The frequency of the first tone and the stimulus onset asynchrony (SOA) between the two tones were varied systematically, whereas the second tone was fixed. Compared with presenting the second tone in isolation, the response to the second tone was enhanced significantly when it was preceded by the first tone. This was observed in 87 of 130 multiunit groups and in 29 of 69 single units with no obvious difference between different auditory fields. Response enhancement occurred for a wide range of SOA (110–329 ms) and for a wide range of frequencies of the first tone. Most of the first tones that enhanced the response to the second tone evoked responses themselves. The stimulus, which on average produced maximal enhancement, was a pair with a SOA of 120 ms and with a frequency separation of about one octave. The frequency/SOA combinations that induced response enhancement were mostly different from the ones that induced response attenuation. Results suggest that response enhancement, in addition to response attenuation, provides a basic neural mechanism involved in the cortical processing of the temporal structure of sounds.
Figure 3: Assembly formation and characterization with Helium Ion Microscopy (HIM), Atomic Force Microscopy (AFM), and Transmission Electron Microscopy (TEM)

Field: Chemistry (Physical Sciences)

Figure 3: Assembly formation and characterization with Helium Ion Microscopy (HIM), Atomic Force Microscopy (AFM), and Transmission Electron Microscopy (TEM), all reveal fractal-like topologies on a surface, (A to G) Longer fractal-like structures, branch-like, and flower-like structures are seen in HIM (A to C) and AFM (D). (E) Representative HIM images for assemblies obtained at different concentrations of pY-AtzAM1 (250 nM- 3 µM) while maintaining a fixed concentration of AtzCM1-SH2 (2 µM). Increasing concentrations of pY-AtzM1 result in larger assemblies with higher fractal dimensions. (F) Df and l, the fractal dimension and lacunarity of the images, are similar for images obtained from different microscopy techniques. HIM images show fractal-like assembly formation with pY-AtzAM1 and AtzCM1-SH2 (G), while the Gly-Ser-rich linker-containing variants form globular assemblies under these conditions (H).
Teaching Tradition Teaches Us

Field: Social Sciences (Social Sciences)

Teaching of Indigenous traditions in the context of an Aboriginal counselling pro­ gram located in a Eurocentric university context can be viewed as both exemplary and contradictory. This article documents how we at the First Nations and Aboriginal Degree Program (FNAC) are challenged to excel at revitalizing tradition­ al healing and teaching strategies while acknowledging the domination of Western theories and practices. Contradictions that have arisen in our daily lived experience of bringing tradition into a modern context are posed as lessons to learn from. Resolv­ ing these controversies on an ongoing basis evidences the struggles and successes of FNAC as a modelofexemplaryIndigenouseducation.
Magnetic resonance spectroscopy in pediatric white matter disease

Field: Medicine (Health Sciences)

Magnetic resonance spectroscopy (MRS) provides in vivo information into the metabolic alterations occurring during the different stages of white matter (WM) diseases. Inborn metabolic/genetic disorders are considered here, while the acquired, mainly inflammatory or hypoxic–ischemic conditions, are addressed in Chs. 28, 30, and 48.
SIGMORPHON 2022 Shared Task on Morpheme Segmentation Submission Description: Sequence Labelling for Word-Level Morpheme Segmentation

Field: Computer Science (Physical Sciences)

We propose a sequence labelling approach to word-level morpheme segmentation. Segmentation labels are edit operations derived from a modified minimum edit distance alignment. We show that sequence labelling performs well for “shallow segmentation” and “canonical segmentation”, achieving 96.06 f1 score (macroaveraged over all languages in the shared task) and ranking 3rd among all participating teams. Therefore, we conclude that sequence labelling is a promising approach to morpheme segmentation.
Workers’ Participation at Plant Level: Lessons from History, International Comparison, and Future Tendencies

Field: Social Sciences (Social Sciences)

In the last chapter, the editors summarize the findings of the volume and draw some general comparative conclusions from the presented chapters. The first aspect which the editors focus on is the argument that history matters, as a crucial precondition to understand the contemporary workings of workers' representation at plant level. In the second part, the continuities and shifts in national models of workers' participation are put in a comparative perspective to illustrate how diversified the landscape of workers' representation at plant level was, is, and continues to be. The last part of the chapter concludes by making some observations regarding the future of models of workers' representation at plant level.
The Prevention of Softball Injuries: The Experience at Yokota

Field: Health Professions (Health Sciences)

Softball injuries occur in a predictable pattern. Review of Emergency Room records at Yokota AB Hospital for three summers showed a high incidence of ankle injuries. Sliding is the cause of many of these injuries. Common sense interventions should reduce the incidence of softball injury. Use of low profile bases or the outlawing of sliding are reasonable interventions that should be considered by policy makers.
SynthI: a new open-source tool for synthon-based library design

Field: Computer Science (Physical Sciences)

Here we present a new open-source toolkit for library design, called Synthons Interpreter or SynthI that allows merging those chemical space of the retrosynthetically generated fragments and the pool of available reagents into a single synthons space. Here synthons are defined as the actual fragments with valid valences and special labels, defining the position and nature of reactive centers. They can be issued from either the “break-up” of reference compounds according to retrosynthetic rules, or real reagents/BBs, after leaving groups transformation. Such an approach not only enables the design of synthetically accessible libraries and analogs generation but also facilitates BB analysis in the medicinal chemistry context. SynthI code is available in https://github.com/Laboratoire-de-Chemoinformatique/SynthI
On Monitoring Processes and Assessing Process Capability under a Hierarchical Model, Part 1

Field: Decision Sciences (Social Sciences)

In this paper we discuss the practical problems involved in following the rational subgrouping principle for control charting as many processes exhibit variation that exceeds the within subgroup variation. As an example we consider simple models for processes where the two extremes 'high frequency variation' and 'low frequency variation' both contribute to inherent process variation. We emphasize the importance of distinguishing between charting aimed at identifying situations where minor process adjustments are needed to compensate for process disturbancies, and charting aimed at demonstrating a state of 'statistical control' with a predictable long-term distribution of process output. For the latter purpose we discuss the modelling of process variation by means of a hierarchical model for normally distributed measurements. The approach is illustrated by a case from the pharmaceutical industry. We finally discuss the assessment of process capability under a hierarchical model for process variation.
Risks of Simultaneous Co-Infection of Dengue and COVID-19 in Bangladesh: Challenges and Recommendations

Field: Medicine (Health Sciences)

The current global COVID-19 pandemic is compounding on populations susceptible to tropical illnesses like dengue in different developing countries like Bangladesh. The growing concern is that Bangladesh is a dengue-endemic zone and the peak transmission occurs in the monsoon season (June to October). In the most recent monsoon, a total of 354 dengue cases have been confirmed until 27th July 2020, data-driven from only 41 hospitals alone. A fifty-three-year-old male patient was found to be co-infected with COVID-19 and dengue fever. Concerns arise as hospitals are increasingly denying to admit the patients. Moreover, reports of the false-positive results in dengue screening tests recorded in different countries further exacerbate the issue. These conditions could postpone the early diagnosis of COVID-19 cases and aggravate the situation. In addition, the overwhelming wave of the dengue cases would be a challenge for the vulnerable health care system of the country which is already under strain due to the COVID-19 pandemic. Failure to establish and implement proper policies might lead to the dengue outbreak with the burdens of the concurrent COVID pandemic, resulting in the collapse of the health and social system, as well as the economic growth of the country.
The Higgs Frontier, Final Technical Report

Field: Physics and Astronomy (Physical Sciences)

In the wake of Run II of the Large Hadron Collider (LHC), the high energy community has gained immense insight into the origin and nature of electroweak symmetry breaking and its connections to dark matter, cosmology, and effective field theory. During this time, our group has completed all of the originally proposed projects relating to the connected topics of Higgs and dark matter (DM). Furthermore, we have made many new discoveries regarding effective field theories (EFTs) and their rich connections to scattering amplitudes.
Ibu Heni 0822-1455-5757 Distributor Herbalife di Sugio Lamongan

Field: Business, Management and Accounting (Social Sciences)

Hubungi Ibu Heni 0822-1455-5757 Alamat, Distributor Herbalife di Halmahera Selatan Maluku Utara\n\nAlamat Agen Distributor Herbalife di Halmahera Selatan Maluku Utara, Distributor Herbalife di Genteng Surabaya, Distributor Herbalife di Gubeng Surabaya, Distributor Herbalife di Gununganyar Surabaya, Distributor Herbalife di Jambangan Surabaya, Distributor Herbalife di Karangpilang Surabaya, Distributor Herbalife di Kenjeran Surabaya, Distributor Herbalife di Krembangan Surabaya\n\nKelas Diet Online Program Slim Marathon 10 Hari Herbalife.\n\nCOACH NIA TLP WA 0822-1455-5757\nKami adalah distributor Resmi Herbalife produsen makanan kesehatan\nKelas Diet Online\nAgen Herbalife\nHerbalife Terdekat\nNo Telepon Kelas Diet Online\n\n\n#DistributorHerbalifediHalmaheraSelatanMalukuUtara, #DistributorHerbalifediGentengSurabaya, #DistributorHerbalifediGubengSurabaya, #DistributorHerbalifediGununganyarSurabaya, #DistributorHerbalifediJambanganSurabaya, #DistributorHerbalifediKarangpilangSurabaya, #DistributorHerbalifediKenjeranSurabaya, #DistributorHerbalifediKrembanganSurabaya\n\n
Using Reduced Intersection Data Set from SHRP2 to Model Intersection Variation

Field: Engineering (Physical Sciences)

Project Description The purpose of this project is to build models of vehicle fuel consumption at intersections using SHRP2 data. Data Request Scope Access to the non-PII "FHWA Reduced Intersection Data Set" containing summaries of over one million SHRP2 intersection traversals. Data Specification Access to the non-PII "FHWA Reduced Intersection Data Set" Vehicle make, model, and year A table indicating which trips have RPM data
Response to Stephen Webb on Christology in Conflict

Field: Arts and Humanities (Social Sciences)

The basic argument of Christology in Conflict is this: if ultimate and universal significance must be ascribed to Jesus Christ, and to him alone, then a reflective account of faith in Jesus (i.e., a Christology) must have a specific structure. In order for anything to count as ultimately significant or meaningful in human life (such as "salvation" and "a saviour"), it must come to pass in, be included in or be coincident with Jesus' reality as a particular person. Or, in the logico-grammatical terms I prefer for making this point, the criterion for what is ultimately meaningful (however characterized) is applicability to the narratively identified Jesus as its ascriptive subject. The point is not to playoff Jesus as a particular person against his general or saving significance, or to give one more weight than the other in Christology (their relationship is not a quantitative one), but to argue that a successful Christology must order them in a certain way. The book makes no attempt to argue for the antecedent of this hypothetical proposition: to show that Jesus Christ alone is ultimately significant. It rather takes this claim for granted and argues that the Christologies of Barth and Thomas Aquinas share a common logical structure appropriate to this claim, while Christologies in modernity (of which Rahner serves as the example) have typically been set up in such a way that they are, despite themselves, incoherent with it.
HOMOCYSTEINE LEVEL IN PATIENTS WITH POLYCYSTIC OVARY SYNDROME WITH AND WITHOUT INSULIN RESISTANCE.

Field: Medicine (Health Sciences)

Until recent period, hyperinsulinemia and hyperandrogenism were thought to be involved in the pathogenesis of polycystic ovary syndrome (PCOS), however, in recent years several studies reported that hyperhomocysteinemia, which may be associated with insulin resistance, plays important role in the pathogenesis of PCOS. Therefore, hyperhomocysteinemia (HHcy) can be considered as one of the newly identified characteristics of PCOS. The aim of the study was to evaluate homocysteine (Hcy) levels in patients with PCOS with and without insulin resistance. The study was conducted in 59 patients with PCOS aged 13-35 (mean age 24.5±3.5). Patients were divided into 2 groups: Group I - 38 patients with PCOS and insulin resistance, Group II - 21 patients with PCOS without insulin resistance. PCOS patients as well were divided into 3 subgroups according to homocysteine values: low - ≤ 6.09 μmol/l, moderate - 6.10-9.33 μmol/l, high >9.34 μmol/l). In patients with PCOS and insulin resistance were established a significant increase in homocysteine levels, HOMA-IR and BMI indicators compared to those patients with PCOS without insulin resistance. In the group of patients with PCOS with insulin resistance homocysteine level with increased and high normal level of homocysteine (high Hcy subgroup, >9.34 μmol/l) were significantly more common (84.2%) compared to patients without insulin resistance (52%). Homocysteine level is significantly elevated in patients with PCOS, and insulin resistance compared to patients without insulin resistance. In the management of patients with PCOS, along with correction of insulin resistance, control and correction of homocysteine level should be considered, which will improve their reproductive outcome.
Pola penggunaan obat anti diabetes mellitus tipe-II pada pasien rawat inap di RSUD Praya tahun 2021

Field: Medicine (Health Sciences)

Diabetes mellitus is a metabolic disease characterized by hyperglycemia due to abnormalities in insulin secretion. The prevalence of people with diabetes mellitus in Indonesia reached 6.2% per year in 2020 and ranks 7th in the world with 8.5 million people. Based on the results of observations at the Praya Hospital in 2021, type-II diabetes mellitus is the 4th highest-order disease suffered by the community, especially Central Lombok Regency, with a total incidence of 131 patients. This study aims to determine the pattern of drug use and HbA1c profile in patients with type-II diabetes mellitus in the inpatient installation of Praya Hospital in 2021. This study was retrospective, using the Nonprobability Sampling method, namely the type of purposive sampling so that a sample of 96 medical records of diabetes mellitus patients was obtained type-II. The data is presented as pie charts and tables in percentages, which were analyzed using Microsoft Excel and SPSS version 25. From the results of this research, it was found that the pattern of drug use at Praya Hospital in 2021 was given the highest from each group namely the oral antidiabetic drug group (OAD) was in the Biguanid class with 61 drugs (8,13%), while insulin drugs were in the Rapid-Acting class with 343 drugs (45,73%), and the OAD + Insulin combination with 119 drugs (15,87%). For the HbA1c profile, high HbA1c levels were found in 76 patients (79%). This shows that blood glucose control is not reasonable. Based on the study's results, the recommended recommendation is that patients routinely control blood sugar and be educated on the accuracy of drug use to control blood sugar.
ChemInform Abstract: Simple and Direct sp3 C—H Bond Arylation of Tetrahydroisoquinolines and Isochromans via 2,3‐Dichloro‐5,6‐dicyano‐1,4‐benzoquinone Oxidation under Mild Conditions.

Field: Chemistry (Physical Sciences)

Abstract DDQ allows the oxidative arylation of activated sp 3 C‐H bonds of tetrahydroisoquinolines, isochromanes and structurally related non‐cyclic substrates.