jimnoneill/paper-to-field-training huggingface dataset:
Antibodies to Thymocytes in Sera of Patients with Schizophrenia

Field: Medicine (Health Sciences)

Sera from healthy people and from patients with schizophrenia were heated at 56° for 30 min and then kept at 4°. These sera were then tested for cytotoxicity and by the indirect immunofluorescence method with thymocytes, bone-marrow cells, and lymph-node cells of adult C 3 H mice. The cytotoxicity index for mouse thymocytes of sera from 60 healthy donors ranged from 0.00 to 0.4, with an average of 0.08. That of sera from 35 patients with schizophrenia ranged from 0.29 to 0.91, with an average of 0.71. The cytotoxicity index for mouse bone-marrow cells of sera from healthy donors ranged from 0.03 to 0.23, whereas that of sera from patients with schizophrenia ranged from 0.00 to 0.14. Sera of patients at dilutions of 1:8-1:32 displayed immunofluorescence of almost 100% of thymocytes and 58-78% of lymphocytes, whereas sera of healthy donors displayed none. We thus conclude that the sera of patients with schizophrenia contain antibodies against thymic antigens localized on thymocytes and thymus-derived lymphocytes.
Book review: Asanga Abeyagoonasekera, Sri Lanka at Crossroads: Geopolitical Challenges and National Interests

Field: Social Sciences (Social Sciences)

Asanga Abeyagoonasekera, Sri Lanka at Crossroads: Geopolitical Challenges and National Interests. Singapore: World Scientific, 2019, pp. 224, S$ 145 (Hardcover), S$48 (Softcover). ISBN: 978-981-3276-73-4.
Multilayered Center-of-Pressure Sensors for Robot Fingertips and Adaptive Feedback Control

Field: Engineering (Physical Sciences)

This letter proposes a sheet-shaped force sensor for covering a robot fingertip. The sensor consists of flexible materials and can be adaptively designed to the shape of the fingertip. When a load acts on the sensor, the contact position and both normal and tangential forces can be detected. Experimental results show the sensor characteristics as follows: The contact position can be estimated in high accuracy if it is enough separated from the boundary of the sensing area, the normal force up to 4 N can be estimated independent with the contact position, and the tangential force can be estimated by calibration while the sensitivity remains to be improved. This letter also presents two feedback control laws of a robot finger mounted with the proposed sensor. One is to keep both a contact position and normal force at constant to a target object, and the other is to keep rolling contact even if the object moves while touching. The availability of the control laws are confirmed through motion experiments.
Some Pharmacological Studies of Ropivacaine in comparison With bupivacaine

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The effect of ropivacaine as a recent amino-amide local anaesthetic compared with bupivacaine on analgesic activities, cardiac contractility, blood pressure, heat rate, Electrocardiogram (ECG) and toxicity was studied. The result of our study revealed that ropivacaine Exhibited a less degree of analgesic potency than bupivacain, it increase the reaction time by 20.6 and up to 167.6%while bupivacaine increased it by 37.32 up to 197.1%. On isolated rabbits heart, ropivacaine and bupivacaine induced a significant dose dependent
THE QUALITY OF INFORMATION PROVIDED BY SURAKARTA TOURIST INFORMATION CENTRE

Field: Social Sciences (Social Sciences)

Denny Setyawan. 2011. THE QUALITY OF INFORMATION PROVIDED BY
SURAKARTA TOURIST INFORMATION CENTRE . English Diploma Program,
Faculty of Letters and Fine Arts, Sebelas Maret University.

This final project based on the job training which was done at Surakarta Tourist
Information Centre (TIC). The objective of this report is identifying the quality of
information provided by Surakarta Tourist Information Centre in providing information
to the tourists who visit Surakarta. The data of this project were taken from observation
and library study, by collecting information from books, websites, documents, and
observation itself.

Based on the observation, it can be concluded that Surakarta Tourist Information
Centre provide good quality information that supported by instruments such as brochures,
leaflets, maps, calendar events etc, which are implementing the characteristic of good
quality information well. Despite there are some lacks and obstacles which come from
technical or internal, those are not significantly affected the quality of information
provided by Surakarta TIC. Impressions issued by the tourists which are reflected in
impressions form can be determine the quality of information provided by Surakarta
Tourist Information Centre. It is shown that they can accept the information and
suggestions provided by TIC’s staff well
High-throughput sequencing reveals circular RNA hsa_circ_0000592 as a novel player in the carcinogenesis of gastric carcinoma

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Background/Aim: Gastric cancer is one of the most common malignant tumors, and its complex pathogenesis has not been fully elucidated. Circular RNAs (circRNAs) are involved in various biological processes and human diseases. However, their exact functional roles and mechanisms of action remain largely unclear. We previously discovered the differential expression of non-coding RNAs (ncRNAs) during the malignant transformation of human gastric epithelial cells. In this study, we investigated the functional roles of a significantly up-regulated circRNA (hsa_circ_0000592) in gastric cancer. Methods:N-methyl-N′-nitro-N-nitrosoguanidine (MNNG)-induced malignant-transformed gastric epithelial cells (GES-1-T) and normal gastric epithelial cells (GES-1-N) were analyzed by high-throughput circRNA sequencing. The top 15 up-regulated circRNAs in high-throughput sequencing results were further confirmed by qRT-PCR in different gastric epithelial cell lines. The function of the most significant circRNA (hsa_circ_0000592) was investigated by using RNA interference (RNAi) assays, fluorescence in situ hybridization analysis (FISH), and bioinformatics prediction methods. Results: A total of 1509 genes were up-regulated and 3142 genes were down-regulated in GES-1-T cells when compared with GES-1-N cells. When compared with GES-1-N cells, hsa_circ_0000592 was obviously up-regulated in GES-1-T cells, as well as in other gastric cancer cell lines. The silencing of hsa_circ_0000592 mRNA led to a decrease in cell proliferation, cell cycle arrest at the G0/G1 phase, an increased rate of apoptosis, and a reduction in cell migration. Furthermore, FISH showed that hsa_circ_0000592 was mainly located in the cytoplasm, and a bioinformatics analysis suggested that hsa_circ_0000592 might function by sponging multiple miRNAs, and most notably four conserved miRNAs, including miR-139-3p, miR-200, miR-367-3p, and miR-33a-3p. Conclusion: This study is the first to identify hsa_circ_0000592 as a novel circRNA with a critical role in MNNG-induced gastric cancer. Due to the essential role of hsa_circ_0000592 in gastric carcinoma cells, it may be considered as a potential biomarker for use in diagnosing gastric carcinoma. Our findings provide a new insight into the function of circRNAs in environmental carcinogen-induced gastric cancer.
Universal off-axis light transmission properties of the bright state in perfectly compensated liquid crystal devices

Field: Physics and Astronomy (Physical Sciences)

We studied the off-axis light transmission characteristics of the bright state of common liquid crystal device modes. The dark state of these device modes is optically compensated to have minimum light transmittance at all angles. Our research shows there is an unexpected universal shape of the off-axis light transmission value in its bright state, regardless of what liquid crystal mode is used. To understand this surprising fact, we consider simple dark and bright state models in terms of phase retardation and transmittance.
COVID-19 adds to Afghan fiscal and political pressures

Field: Social Sciences (Social Sciences)

Significance The government is struggling to manage the health crisis and is distracted by peace negotiations, the impending US troop withdrawal and its own factional infighting. Impacts Foreign direct investment is in decline and will not pick up unless there is clarity about a political settlement. A change in government resulting from the Doha peace talks could up-end fiscal management. Healthcare and social investment policy assume the Taliban will not be influencing policy by end-2021; this may be wrong. The IMF's recommendation of an audit of COVID-19 aid highlights the corruption that blights the government's record.
The Lrp Family of Transcription Regulators in Archaea

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Archaea possess a eukaryotic-type basal transcription apparatus that is regulated by bacteria-like transcription regulators. A universal and abundant family of transcription regulators are the bacterial/archaeal Lrp-like regulators. The Lrp family is one of the best studied regulator families in archaea, illustrated by investigations of proteins from the archaeal model organisms: Sulfolobus , Pyrococcus , Methanocaldococcus , and Halobacterium . These regulators are extremely versatile in their DNA-binding properties, response to effector molecules, and molecular regulatory mechanisms. Besides being involved in the regulation of the amino acid metabolism, they also regulate central metabolic processes. It appears that these regulatory proteins are also involved in large regulatory networks, because of hierarchical regulations and the possible combinatorial use of different Lrp-like proteins. Here, we discuss the recent developments in our understanding of this important class of regulators.
Phenomenological profile of top squarks from natural supersymmetry at the LHC

Field: Physics and Astronomy (Physical Sciences)

In supersymmetric models with radiatively-driven naturalness and light higgsinos, the top squarks may lie in the 0.5- 3TeV range and thus only a fraction of natural parameter space is accessible to LHC searches. We outline the range of top squark and lightest SUSY particle masses preferred by electroweak naturalness in the standard parameter space plane. We note that the branching fraction for b-> s\gamma decay favors top squarks much heavier than 500 GeV. Such a range of top-squark mass values is in contrast to previous expectations where m(stop)<500 GeV had been considered natural. In radiative natural SUSY, top squarks decay roughly equally via t1-> bW1 and Z_{1,2} where W1 and Z_{1,2} are higgsino-like electroweak-inos. Thus, top squark pair production should yield all of t\bar{t}+\eslt, t\bar{b}+\eslt, b\bar{t}+\eslt and b\bar{b}+\eslt signatures at comparable rates. We propose that future LHC top squark searches take place within a semi-simplified model which corresponds more closely to expectations from theory.
New methodologies for the introduction of the SCF3 and Cl groups by C(sp3)-H bond functionalization and the design of original fluorinated electrophilic reagents

Field: Chemistry (Physical Sciences)

Le domaine de recherche de la chimie du fluor a connu un essor considérable. En particulier, le motif SCF3 et plus récemment les groupements SCF2R (R = H, SO2Ph, SAr, COAr, Rf) ont fait l'objet d'une attention particulière de la part de la communauté scientifique du fait de leurs propriétés remarquables. Dans ce contexte, le développement de nouvelles méthodologies et de réactifs originaux pour l'introduction de ces groupements fluorés a suscité un fort intérêt. En conséquence, les objectifs de cette thèse ont été 1) de développer de nouvelles méthodologies pour la fonctionnalisation de liaisons C(sp3)-H par l'introduction directe d'un motif SCF3 catalysée par des métaux de transition, et son extension à d'autres groupements fonctionnels ainsi que 2) de concevoir et étudier de nouveaux réactifs fluorés électrophiles. La première partie de cette thèse a été dédiée au développement d'une réaction de trifluorométhylthiolation d'amides aliphatiques catalysée au palladium, une transformation inédite (Chapitre 2). Puis, la chloration d'amides aliphatiques catalysée au palladium, dans des conditions douces, a été étudiée (Chapitre 3). Enfin, une nouvelle voie de synthèse pour accéder aux sulfénamides trifluorométhylés a été développée (Chapitre 4). Cette approche a été étendue à la préparation d'un nouveau réactif électrophile pour l'introduction du groupement SCN. De plus, un réactif électrophile original, source du motif SCF2PO(OEt)2, a été synthétisé et appliqué à la construction de liaisons C-SCF2PO(OEt)2, N-SCF2PO(OEt)2 et S-SCF2PO(OEt)2 ainsi qu'à la synthèse d'un composé d'intérêt biologique (Chapitre 4).
Specifically unspecific – Simple devices as feasible and effective enrichment for small mammals

Field: Veterinary (Health Sciences)

Although enrichment is an essential part of modern zoo animal husbandry, research on effective enrichment for small mammals is scarce, albeit they are regularly kept in zoos. To develop solutions that are inexpensive, readily applicable, and adaptable for a variety of species, we investigate whether three types of simple enrichment devices (SEDs) – object, olfactory, and food-motivated – elicit positive interactions in various zoo-housed small mammal species. In this preliminary exploration study, we evaluate if amount of enrichment interactions, display of behavioral stress reactions, and display of stereotypic behaviors vary, if different types of SEDs are provided. Therefore, we observed 39 individuals of ten species, most of which are underrepresented in enrichment literature: Eastern quoll (Dasyurus viverrinus), round-eared elephant shrew (Macroscelides proboscideus), aardvark (Orycteropus afer), southern tamandua (Tamandua tetradactyla), northern Luzon giant cloud rat (Phloeomys pallidus), green acouchi (Myoprocta pratti), South African springhare (Pedetes capensis), aye-aye (Daubentonia madagascariensis), golden lion tamarin (Leontopithecus rosalia), and Javan mouse-deer (Tragulus javanicus) housed in Frankfurt Zoo, Germany. All focal individuals interacted with at least two types of SEDs and around 80% interacted with all types of SEDs, resulting in a considerable amount of time spent with the enrichment. There was a preference for food-motivated enrichment. Neither behavioral stress reactions nor stereotypic behaviors differed if different types of SEDs were present. Model selection showed that GLMs explaining enrichment interactions improved if the variable ‘individual’ instead of ‘species’ was included, suggesting that reactions towards unspecific SEDs might be more individual-driven than species-specific. Because individuals of all species chose to interact with the SEDs and we did not find behavioral indicators for stress elicited by the SEDs, we advocate for the regular provision of SEDs for small mammals in human care.
The Effect of Adding Oak Bark Powder to the Diet on Some Productive and Immunological Characteristics of Broiler Chicks

Field: Agricultural and Biological Sciences (Life Sciences)

Background and Objective: The current study investigated whether the addition of oak bark powder to poultry diets improved the production and immunological traits of broilers.The goal of farmers is to increase immunity to reduce the risk of different diseases and reduce the use of antibiotics, which negatively affect human and animal health.The attainment of this goal leads to an increase in profits for the broiler industry.We aimed to study the effect of oak bark powder on the productive, physiological and immunological characteristics of broiler chicks.Methodology: A total of 180 unsexed Ross chicks (initial weight of 41 g per chick) were raised in a closed house that was divided into pens, each of which was 3 m 2 and the chicks were randomly distributed to the pens.Four treatments with 45 chicks each were tested.Three replicates were carried out for each treatment.Results: The results showed that there were no significant differences in the final body weight, cumulative weight gain, total feed intake, total feed conversion ratio, mortality rate, economic figure and hemoglobin level of the chicks.However, the addition of oak powder had a significant effect on decreasing the incidence of Newcastle disease and infectious bursal disease.There was a significant increase in the number of blood cells for all levels of oak powder addition, resulting in a significant improvement in the number of red blood cells of the broiler chicks fed the 3% oak bark powder and a significant improvement in the number of white blood cells of the broiler chicks fed the 1% oak bark powder.Conclusion: Because the addition of oak bark powder improved the immunological and blood parameters of broiler chicks, it is recommended to add oak bark powder to broiler chick diets to enhance immunity and improve blood parameters in broiler chicks.
International standards of law-making: the concept and classifications

Field: Social Sciences (Social Sciences)

The article is devoted to the study of the concept of international legal standards and the definition of international standards of law-making, the establishment of their characteristic features, and their classification. It is noted that in modern conditions, the transformation of legal systems must comply with international standards, i.e., those value guidelines that are formed under the influence of the international community. International standards of lawmaking are a separate group of international legal standards that ensure the existence of the concept of the “ideal construction” of law, which, despite the existence of different legal systems, includes the achievements of the latter and serves as a benchmark for the development of effective and modern legislation. It is emphasized that international standards of lawmaking create ideological and value foundations, priorities, and general guidelines, given which, further reform and development of means of creating high-quality and effective legislation should take place to fully ensure the fulfillment by the state of its international obligations to ensure and protect human rights, freedoms, and legitimate interests. The author argues that international standards of law-making include the basic international standards in the field of human rights protection, which are enshrined in UN conventions and must be implemented by the participating states, UN and Council of Europe conventions on combating corruption, as well as many fundamental documents of the Venice Commission, which reveal the content of the principles of the rule of law, the practice of the ECHR in interpreting the provisions of the 1950 Convention for the Protection of Human Rights and Fundamental Freedoms, etc. It is proposed to classify international standards of law-making according to: the territory (space) of their creation, the level of formal binding force, the form of enshrinement, and their content. It is emphasized that the content of international standards of lawmaking best reveals their specificity and provides their division into: international standards for the implementation of the principle of the rule of law; international standards for the formation of anti-corruption legislation and anti-corruption infrastructure; international standards for the foundations of democratic functioning of government bodies; international standards for European integration and harmonization with EU law.
Statins: Not all are benefits

Field: Medicine (Health Sciences)

Introduction: Dyslipidemia is a group of diseases whose common characteristic is the abnormal concentration of blood lipoproteins. An abnormally high concentration leads to the formation of arteriosclerosis and an increased risk of cardiovascular diseases, the main cause of mortality. \nObjectives: To evaluate the impact of hypercholesterolemia and to know the effects of the use of statins as treatment in primary and secondary prevention. \nMethod: Systematic review in scientific databases of studies conducted in primary and secondary prevention for the treatment of hypercholesterolemia with statins assessing benefits and harms. \nResults: The prevalence of hypercholesterolemia is increasing due to the lack of healthy life habits in the population. There are studies that indicate that levels close to normal can be improved with hygienicdietetic measures and when these levels reach a certain value or do not change with these measures, one must move on to pharmacological treatment with statins, always assessing the risks and benefits in each patient. . \nConclusions: Hypercholesterolemia requires patient awareness in the problem of arteriosclerosis and its participation in the treatment since, being an asymptomatic disease in the early stages, many of them are not aware of the risks. Statins with their side effects are controversial and research continues on their use as a treatment. \n
All-systolic non-ECG-gated myocardial perfusion MRI: Feasibility of multi-slice continuous first-pass imaging

Field: Medicine (Health Sciences)

The presented methods and results demonstrate feasibility of the proposed approach for high-resolution non-ECG-gated FPP imaging of 3 myocardial slices at the same systolic phase, and indicate its potential for achieving desirable image quality (high CNR and no dark-rim artifacts).
SPONTANEOUS REGRESSION OF PRIMARY RENAL CELL CARCINOMA WITH INFERIOR VENA CAVAL TUMOR THROMBUS

Field: Medicine (Health Sciences)

No AccessJournal of UrologyCLINICAL UROLOGY: Case Reports1 Jan 2002SPONTANEOUS REGRESSION OF PRIMARY RENAL CELL CARCINOMA WITH INFERIOR VENA CAVAL TUMOR THROMBUS K.O. KOBAYASHI, TAKASHI SATO, KEN-ICHI SUNAOSHI, ATSUSHI TAKAHASHI, and MITSUHARU TAMAKAWA K.O. KOBAYASHIK.O. KOBAYASHI , TAKASHI SATOTAKASHI SATO , KEN-ICHI SUNAOSHIKEN-ICHI SUNAOSHI , ATSUSHI TAKAHASHIATSUSHI TAKAHASHI , and MITSUHARU TAMAKAWAMITSUHARU TAMAKAWA View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)65424-9AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "SPONTANEOUS REGRESSION OF PRIMARY RENAL CELL CARCINOMA WITH INFERIOR VENA CAVAL TUMOR THROMBUS." The Journal of Urology, 167(1), pp. 242–243 References 1 : Spontaneous regression of primary and metastatic renal cell carcinoma. J Urol1996; 155: 1385. Link, Google Scholar 2 : Radiologic assessment of renal masses. Radiology1997; 202: 297. Google Scholar 3 : Renal adenocarcinoma. Urol Survey1980; 30: 129. Google Scholar From the Department of Urology, Oji General Hospital, Tomakomai, and Department of Urology and Radiology, Sapporo Medical University, School of Medicine, Sapporo, Japan© 2002 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 167Issue 1January 2002Page: 242-243 Advertisement Copyright & Permissions© 2002 by American Urological Association, Inc.Keywordsthrombusvena cava, inferiorcarcinoma, renal cellMetricsAuthor Information K.O. KOBAYASHI More articles by this author TAKASHI SATO More articles by this author KEN-ICHI SUNAOSHI More articles by this author ATSUSHI TAKAHASHI More articles by this author MITSUHARU TAMAKAWA More articles by this author Expand All Advertisement PDF downloadLoading ...