jimnoneill/paper-to-field-training huggingface dataset:
An efficient and reliable service customized routing mechanism based on deep learning in IPv6 network

Field: Computer Science (Physical Sciences)

Abstract Best‐effort service model of traditional routing is gradually hard to meet the personalized demands under the rapid development of network technologies (e.g. 5G and IPv6). Therefore, service customization should be considered. In this work, a service customized routing mechanism based on deep learning in IPv6 network is proposed, which includes deep learning‐based service customization module, reliability evaluation module, and routing calculation module. The first module uses neural network to learn the complex service customization function, which can quickly output win‐win customized service strategies based on user demands. The second module can quantify the reliability of service routing paths, where not only the link status of IPv6 Neighbor Unreachable Detection (NUD) is considered, but also propose link performance weights to ensure the reliability of differentiated service performance. The third module uses the gray wolf optimization algorithm to calculate an optimal routing path to forward services with the customized strategies as the constraints and the maximum reliability and minimum cost as the goal. Finally, the mechanism is tested on the IPv6 Source Address Validation Improvement (SAVI) platform, which can reduce the execution time by 12.25% and improve the average routing reliability, user and ISP satisfaction by 9.0%, 40.45% and 7.4%, respectively.
Political Participation and Pleasure in Green Lifestyle Journalism

Field: Social Sciences (Social Sciences)

This article examines the reportage of green lifestyle practices across the online sites of major British newspapers. The articulation of “green lifestyle journalism” in the study is suggestive of its complex identity, given its implication in existing orders of consumption while also expressive of emerging everyday practices that potentially and variously challenge those orders of consumption. The study enquires into whether such green lifestyle journalism stories are, in fact, reported across different online sites, and if so, in which publications and how such stories are classified within online menus. It also examines the range of reported environmental lifestyle practices and how they are attributed with meaning, including their engagement with the concept of pleasure and its association with political participation. The study reveals that the pleasures associated with sustainable living are often marginalized, and instead an ethical consumer is commonly posited who is variously cognitively deficient, worried about the environmental consequences of their everyday behavior, or concerned about their inability to realize their desires to engage in sustainable lifestyle practices. The article also examines those instances when the pleasures of a more sustainable lifestyle are represented as deriving from the implementation of environmental practices and technologies in everyday, domestic contexts, and also when they are illustrated as the product of civic and political engagements with issues of sustainability.
Spirituality in Tribal India

Field: Social Sciences (Social Sciences)

Spirituality in tribal religion was not a topic of academic interest at a time when tribes were studied as 'others'. Studies presented the faith, beliefs, and practices of tribes as magic, animism, animatism, etc., and lacked the theoretical rigour to consider the belief systems as religions. However, the confusion no more stands at present. Nevertheless, the spiritual aspect of tribal religion is yet a least studied topic. What has been understood as spirituality is a perspective related to the tribal 'world of spirits', the essence of their beliefs in ancestor spirits and spirits or souls of natural objects. In recent years, eco-spiritualism has emerged as an interesting area of investigation, but it limits its scope to tribal ecological knowledge. A few Christian scholars have tried to explore tribal spirituality from their perspectives. Spirituality in tribal religion appears as a passing reference in some studies. This emerging trend is undoubtedly an inciting academic motivation for an understanding of the spiritual dimension of tribal religion. The present chapter is a preliminary attempt in this direction. The chapter tries to explore spirituality in tribal faith, belief, and practices with reference to worldly and cosmic consciousness in the religious worldview of some Indian tribes.
Impact of Pranayama on Cardiopulmonary Health

Field: Health Professions (Health Sciences)

Pranayama, an ancient Indian breathing exercise technique, regulates the length, frequency, and timing of breaths. Pranayama releases the breath and allows prana also facilitates the flow of life force throughout the body, helping it to heal, relax, and become more energized. Cardiovascular endurance, also known as aerobic fitness. Benefits of cardiovascular endurance include lowering blood pressure and cholesterol, reducing the risk of heart and blood vessel problems, strengthening the heart and lungs, enhancing mental performance and improving the overall quality of life. Nose is the primary system for inhalation and exhalation in many breathing exercises. This technique is based on the extraordinary sensitivity of our lungs, optimizing the air we breathe for entry into the respiratory system, where the air's temperature and humidity are adjusted. This chapter will explain how Pranayama enhances airflow into the body, generating both physical and subtle heat that ignites the internal fires of the body and mind and that improves cardio-pulmonary health by enhancing the circulation.
Restrictions in Distinguishing Lung Disease in α1-Antitrypsin Deficiency from COPD

Field: Medicine (Health Sciences)

Poster: ESTI 2016 / P-0005 / Restrictions in Distinguishing Lung Disease in α1-Antitrypsin Deficiency from COPD by: P. Konietzke 1, B. Jobst1, A. Opgenorth1, K. Kenn2, I. Jarosch2, H. U. Kauczor1, M. O. Wielputz1; 1Heidelberg/DE, 2Schonau am Konigssee/DE
Proteome Analysis of Phase-Separated Condensed Proteins\nwith Ionic Surfactants Revealed Versatile Formation of Artificial\nBiomolecular Condensates

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The\nformation of highly condensed, native proteins is important\nfor the development of protein-based drugs and materials. In the cell,\nvarious types of liquid droplets with broad functions are formed by\nthe spontaneous condensation of protein, as a physiological response.\nThese droplets lack a surrounding membrane but are phase-separated\nfrom the water medium. These types of phase-separated states of proteins\nhave potential applications in biotechnology. Recently, we have developed\nan artificial phase-separated liquid of condensed native proteins,\ntermed a protein condensate (PC), formed by electrostatic complexation\nwith ionic surfactants. Here we report the applicability of PC formation,\nstudied using an <i>E. coli</i> extract as the protein source.\nThe addition of anionic and cationic surfactants at a specific ratio\nto the <i>E. coli</i> extract resulted in PC formation.\nA proteome analysis showed that the PC thus formed contained about\n600 kinds of proteins, representing 65% of the uniquely detected proteins\nand confirming the high versatility of PC formation. A statistical\nanalysis revealed that a variety of types of proteins with a wide\nrange of molecular weights and isoelectric points could form PCs.
Automating relative debugging

Field: Computer Science (Physical Sciences)

The creation of a new program version based on an existing version is known as software evolution. In 1994, Abramson and Sosic proposed relative debugging to assist users to locate errors in programs developed with software evolutionary techniques. Relative debugging is a paradigm described by D. Abramson et al. (1996) that enables programmers to locate errors by comparing the developed (evolved) program with the original (existing) program as they are concurrently executed. The aim of the proposed research is to further enhance the currently defined paradigm by (partially or completely) automating the process of relatively debugging. We investigate the possibility of automatically identifying the data structures and program points, normally performed by the user, where values should be equivalent during program execution. Minimizing the user's involvement will reduce the cost of enhancing, maintaining and porting software, and has the potential to provide significant productivity gains on current practices in software development.
A multiscale correction to the Black–Scholes formula

Field: Mathematics (Physical Sciences)

Based on a new multiscale hybrid structure of the volatility of the underlying asset price, we study the pricing of a European option in such a way that the resultant option price has a desirable correction to the Black–Scholes formula. The correction effects are obtained by asymptotic analysis based upon the Ornstein–Uhlenbeck diffusion that decorrelates rapidly while fluctuating on a fast time‐scale. The subsequent implied volatilities demonstrate a smile effect (right geometry), which overcomes the major drawback of the Black–Scholes model as well as local volatility models, and move to a right direction as the underlying asset price increases (right dynamics), which fits the observed market behavior and removes the possible instability of hedging that the local volatility models may cope with. Further, we demonstrate that our correction brings significant improvement in terms of fitting to the implied volatility surface through a calibration exercise. Copyright © 2014 John Wiley & Sons, Ltd.
Association of Risk Factors, Frequency and Outcomes of ST-Elevation Segment in MI with Patients' Birth-Month; Data from a Cohort Study in Western Iran

Field: Medicine (Health Sciences)

BACKGROUND Given newly debates on the association of birth-month with various diseases, we investigated the association of patients' birth-month with a burdensome lethal disease, ST-elevation myocardial infarction (STEMI). METHODS The data comes from an ongoing cohort-registry conducted on patients with STEMI registered to a mega cardiovascular hospital, in Western Iran (2016 - 2019). Baseline and follow-up data were collected using the European observational registry program (EORP) case report form, through interviewing eligible patients and reviewing their medical records. The quality of data as well as ethics considerations has been approved by EORP and Kermanshah University Medical Sciences (KUMS) Ethics Committees. RESULTS Among 2341 patients (81.5 % male) analysed, the peak of event [myocardial infarction (MI)] was 10 am followed by 8 pm. Their mean age (± SD) was 60.34 ± 12.40 years, minimum 19 years and maximum 96 years. March was significantly more frequent birth-month (16.4 %) (p < 0.001). Nevertheless, in terms of MI incidence, no significant variation was found between 12 months of a year, as well as the four seasons. The most common risk factors were smoking, hypertension, hypercholesterolemia and diabetes. About 3.8 % (n = 90) died in hospital (23 women). More than 6 % of patients expired during the first year of follow up. Although birth- month of 18.89 % (n = 17) of those expired was March, the difference was not significant (p = 0.025). CONCLUSIONS Among 12 months, March was highly significant common birth-month among patients with STEMI; however, this birth-month was not significantly associated with MI frequency of MI risk factors and/or a worse outcome. KEY WORDS Birth Month, Acute Myocardial Infarction, Heart Attack, Risk Factors, Outcomes
Issues in the Assessment of Outcome in Family Therapy

Field: Psychology (Social Sciences)

This paper examines several issues in family therapy outcome research. These include the need to consider numerous population and treatment variables, the influence of treatment goals and values upon the research, the difficulties in defining and operationalizing family treatment, the choice between emphasizing integrity of treatment or randomness of sampling, the selection of measurement methods, the controls needed in research design, the extent of generalizability of results, the importance of efficiency of treatment, and the special role of deterioration effects. Throughout, the need for a multivariate schema for conceptualizing this research and special attention to the role of values and assumptions in it are highlighted.
Hereditary Elliptocytosis

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The of the erythrocyte biochemistry in 15 cases of hereditary elliptocytosis, shown and both before and after incubation with APHand an increase of G6PDH, NAPDH-GR, HK, PFK, ENOL, and LDH activities. A slight decrease in ALD and ATP-ase was also observed. The raised values of many enzymatic activities may be a consequence of hy-perhaemolysis and thus the presence of a young erythrocyte population containing an increased concentration of enzymes. The normal but low values of ATP-ase and the ALD deficiency may be the result of structural alterations of the erythrocyte membrane.
Fast Prescreening for GPR Antipersonnel Mine Detection via Go Decomposition

Field: Engineering (Physical Sciences)

Ground-penetrating radar (GPR) has been widely used for antipersonnel mine (APM) detection. However, its efficiency is often impaired by high false alarm rate (FAR) caused by the ground clutters. In this letter, a novel robust principal component analysis (RPCA)-based method is proposed for fast prescreening of APM in GPR image. Taking advantage of low rank and sparse structure of GPR image, the proposed method first adopts an efficient RPCA technique—Go Decomposition (GoDec)—to extract the target image. Then, thresholds are applied to the extracted image to detect the target and reject false alarms. The proposed method enjoys two advantages over traditional methods: 1) the ability of reducing FAR while maintaining high probability of detection (PD) in strong noise and clutter environment and 2) the fast detection guaranteed by the modified GoDec that yields results within several iterations. Extensive simulations and laboratory experiments are conducted to validate the proposed method, and the results are satisfactory (high PDs up to 99% and low FARs).
Figure S4 from BRAF and MEK Inhibitors Increase PD-1-Positive Melanoma Cells Leading to a Potential Lymphocyte-Independent Synergism with Anti–PD-1 Antibody

Field: Medicine (Health Sciences)

<p>Fig. S4. PD1+ melanoma cells proliferate less than their PD1- counterpart. A representative proliferation assay is shown. The proliferation of PD1+ and PD1- mMel2 patient-derived melanoma cells was evaluated by the vital dye CFSE staining and fluorescence intensity decrement over time.</p>
Environmental Conservation as Source of Building Peace – Myth or Reality

Field: Social Sciences (Social Sciences)

Peace-building is both the theory and practice of identifying the conditions that can lead to a sustainable peace . It is must for human development and effective environmental management, both of which are critical to achieving national and regional goals. Applying peace building to environmental crises would include developing an understanding of eco-justice and promoting its advancement. Both peace and environmental educators have a common goal-of stopping violence. Both negative and positive peace implies a commitment to nonviolence in inter human relations and human relationships with nature.
A Systematic Review to Assess the Use of Peer Mediated Interventions for Children with Autism When Autistic Children Serve as Peer Instructors and Models

Field: Medicine (Health Sciences)

Abstract Autism spectrum disorder is a neurodevelopmental disorder characterized by deficits in social communication, social interactions and restricted, repetitive and stereotyped patterns of behavior, interest or activities. These deficits hinder autistic children’s social and communicative skills. Peer-mediated interventions (PMIs) have been found effective in the development of communication, play and social skills in individuals with ASD. In PMIs typically developing children are trained to be peer models of socially acceptable behavior for children with ASD. This however may contrast with literature indicating that the most effective peer models are individuals who share similarities with the learner. The current study was a systematic review of literature to determine if there is sufficient empirical research to support the use of PMIs for autistic children when autistic children are utilized as peer instructors and models. A total of 74 studies were assessed for inclusion criteria. No articles were left in this literature review, which concluded as empty. Key words: peer-mediated intervention, peer-based intervention, peer modeling, autism
Validity of the DIAL-R for Identifying Children with Special Education Needs and Predicting Early Reading Achievement

Field: Social Sciences (Social Sciences)

The validity of the DIAL-R for identifying special-needs children and predicting early achievement was investigated for 463 prekindergarten screening program participants. The DIAL-R was found to be useful for selecting children in need of follow-up services. A decision-to-refer rule based on one low DIAL-R area score was most satisfactory in identifying special-needs children (sensitivity = .57; specificity = .95). All children with more disabling educational handicaps and one-half of those with less severe impairments were identified. Findings supported the use of locally validated decision-to-refer rules and multiple cut-off scores (OK, monitor, refer). The correlation between DIAL-R and kindergarten Clymer-Barrett Readiness Test scores was r = .64 (p <.01); the correlation of the DIAL-R with first-grade Stanford Reading Test scores was .54 (p <.01). Consistent with findings for other screening instruments, results suggested that the DIAL-R has limited validity for predicting the achievement of individual children beyond kindergarten.
On compression of electromagnetic pulses in dielectric plates

Field: Physics and Astronomy (Physical Sciences)

The results of theoretical investigation of propagation of electromagnetic wave pulses in nonlinear dielectric plates, taking into account the dispersion introduced by the plate to the maximum possible extent, are presented. The investigation is aimed at obtaining the shortest possible pulses of electromagnetic waves. Pulse compression is based on the collapse of electromagnetic waves in transparent dielectrics with electronic non-linearity. The integral equation for describing the pulse compression is derived, and conditions under which a pulse is compressed relative to time and one of the transverse coordinates are determined. Numerical simulation shows that quite short (on the order of a few femtoseconds) pulses can be obtained in this way.
A tumor-associated antigen in gastric cancer secretions.

Field: Medicine (Health Sciences)

Summary An antigen, distinct from Gold9s carcinoembryonic antigen, was identified in 91% of gastric cancer secretions (GCJ). Reacted with rabbit immune serum against GCJ, this antigen appears as one precipitin line among others on double diffusion in agar gel. When the immune serum has been absorbed with noncancer secretions, it gives a distinctly prevalent line with GCJ both on immunodiffusion and by immunoelectrophoresis. After absorption with normal human plasma, the gastric cancer antigen appears on immunoelectrophoresis as a sharp single line in the β region with a mobility greater than Gold9s carcinoembryonic antigen. Gastric cancer antigen has an immunologically reactive carbohydrate moiety and is different from blood group substances. It was not detected in the gastric tumor itself. The corresponding precipitin line disappeared when the immune serum was absorbed with GCJ, thus establishing its pathognomonic significance. Detection of gastric cancer antigen may be crucial for early diagnosis, particularly in younger, still salvageable patients, when there is free HCl on gastric analysis.
Molecular and cellular studies of Drosophila neuroserpin Spn4A and its polymer-forming mutants

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Serpins (Serine Protease Inhibitors) are expressed by most organisms and perform a variety of functions. Most serpins inhibit proteases by undergoing a unique conformational change. They are clinically relevant in two ways. First, introduction of single amino acid point mutations transforms the serpins’ labile conformations into pathogenic, inactive polymers causing “serpinopathies”. In particular, human neuroserpin is a brain-specific serpin that, when mutated, causes a debilitating early onset dementia through unknown cellular pathways. Second, serpins are currently under investigation as therapeutic inhibitors of proprotein convertases (PCs). PCs are associated with some bacterial and viral infections as well as cancer. However, no comprehensive investigation into the cellular effects of PC inhibitor expression in mammalian cells has been performed. This thesis details the use of the Drosophila serpin, Spn4A, to address the cellular pathways mediated by serpin polymers or PC inhibition. Spn4A is a neuron-specific, secretory pathway serpin that inhibits Drosophila or human PCs. We hypothesized that Spn4A mutants, encoding homologous disease-causing mutations in human neuroserpin, would form pathogenic polymers and represent an ideal candidate for generating a cell-based and transgenic Drosophila serpinopathy model. Further, we hypothesized that we could evaluate the cellular response to PC inhibition and polymer accumulation by transcriptome profiling of H4 human neuroglioma cells expressing Spn4A wild-type and mutants. We established an expression system using Spn4A and its mutants in H4s. Subsequently, we used microarray analysis to simultaneously address how serpin polymers may induce cytotoxicity as well as the effects of proprotein processing inhibition in neuroglioma cells. We demonstrated that Spn4A mutants formed polymers, were retained in the endoplasmic reticulum, and lacked inhibitory function, but induced few changes on the transcriptome (under 20 genes differentially regulated). To this end, we have developed transgenic Drosophila overexpressing Spn4A variants to further investigate the biological impact of Spn4A mutants. Next, we analyzed the response to the PC inhibitor, Spn4A, and found marked changes in genes related to malignancy. Our genome-wide gene expression studies have provided novel insights into cellular changes in response to polymeric or PC-inhibiting serpins, and establish the foundation for future functional studies.