jimnoneill/paper-to-field-training huggingface dataset:
Design and implementation of a new variable configuration electric vertical take-off and landing urban air traffic vehicle

Field: Engineering (Physical Sciences)

In response to the growing traffic congestion in countries around the world, the idea of urban air traffic solutions has been proposed internationally. The electric vertical take-off and landing vehicle (eVTOL) was born out of this idea. Existing vehicles of this type have obvious problems in terms of take-off and parking footprint, and in terms of energy conversion efficiency of aerodynamic forces during normal flight. Based on these problems, this paper proposes a hybrid variable configuration layout eVTOL vehicle based on a hydraulic-linked rotating mechanism. In this design, the rotating and folding wing design revolutionises the problem of large space occupation during take-off and parking, while the hybrid power system layout with vertical take-off and landing and fixed wing flight modes successfully changes the poor endurance of this type of aircraft. Through motion simulation and dynamic finite element analysis, the key parameters of this design have achieved the design objectives. The design also relies on the low latency characteristics of 5G technology and the urban transportation network under the sharing economy, and further proposes a low usage threshold framework for unmanned vehicles, which will help China's future intelligent air transportation system to lead the development.
Characterization and purification of proteins which bind high-density lipoprotein. A putative cell-surface receptor

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

High-density lipoprotein (HDL) is shown by ligand blotting to bind membrane-associated polypeptides with sizes of 60, 100 and 210 kDa. Binding was concentration-dependent and competed by excess unlabelled HDL. All the major apolipoproteins of HDL, apoA-I, apoA-II and apoA-IV, bound independently. The 100 kDa and 210 kDa HDL-binding activities were purified from membranes of Hep3B tumour cells by ion-exchange chromatography and gel filtration. The binding activities at 100 kDa and 210 kDa co-purified. After treatment with disulphide-reducing reagent, the 210 kDa band was no longer present and an increase was observed in the amount and binding ability of the 100 kDa polypeptide. The 100 kDa binding protein labelled at the cell surface with 125I could be immunoprecipitated after cross-linking to cell-surface-bound HDL. It is proposed that this HDL-binding activity, a putative cell-surface receptor for HDL, exists totally or in part as a high-molecular-mass complex composed of 100 kDa subunits.
Evaluation on the Development Mode and Process of Modernized Education in China

Field: Social Sciences (Social Sciences)

Modernized education is an important supporting part for accelerating the construction of a modernized country.Based on references available at home and abroad, this author collects and borrows modernized education evaluation systems in all aspects.Based on the achievements, first, this article analyzes development mode of modernized education, detailing main characteristics and changes of modernized education process; second, it makes a systematic design of modernized education indices system to evaluate the overall process of modernized education from educational development level, educational condition and teaching faculties.Research results show, nature of modernized education is to continuously improve three-level enrollment rate, and China has made obvious progress in modernized education, reaching 90%.During the 13th five-year plan, senior high school education and higher education are accelerated to promote the upgrade of educational development strategy, and it is predicted that China will have its modernized education goal achieved by 2020 or earlier.
Samenvatting van de standaard 'Osteoporose' van het Nederlands Huisartsen Genootschap

Field: Medicine (Health Sciences)

The Dutch College of General Practitioners issued a standard 'Osteoporosis' with guidelines for prevention, diagnosis and treatment in patients who have a (probably) osteoporotic fracture, who are taking at least 7.5 mg corticosteroids per day for at least six months or who have questions about osteoporosis. - The core of the management is information about lifestyle (stimulation of physical activity) and nutrition. Prevention of falling is to be stimulated; sedatives, excessive drinking and smoking are to be discouraged. - Persons who cannot achieve a calcium intake of 500 mg/day, patients with osteoporotic fractures and takers of biphosphonates or corticosteroids whose calcium intake is insufficient are eligible for calcium suppletion. - In patients with (probably) osteoporotic fractures and those taking 7.5 mg corticosteroids per day for longer than six months preventive treatment may be considered with alendronic acid for a maximum of 3 years, if several vertebral fractures are visible roentgenologically, the T score is < -2.5 (if age < 70 years) or the Z score < -1.0 (> 70 years).
The Sonority Dispersion Principle in Albanian

Field: Arts and Humanities (Social Sciences)

An important pattern that is based on the sonority relationship is the Sonority Dispersion Principle (SDP) formulated by Clements (1990). This principle can serve as the basis for classifying syllable types in terms of relative complexity. The notion “dispersion in sonority” clearly defined within a demisyllable. According to this principle, the sonority slop from the onset to the syllable nucleus is maximized and from the nucleus to the coda is minimized. The purpose of this paper is to provide some data on the Albanian language by dividing the sounds within the demisyllable, by analyzing the combinations of sounds in the onset and in the coda. According to SDP, in Albanian the optimal syllable structure with 2 elements is C[stop]V, while among the optimal structures with 3 elements, the types C[stop]VC[glide], C[stop]C[liquid]V, C[stop]C[nasal]V and C[fricative]C[liquid]V predominate. The analyzed data are important and serve to deeply recognize the characteristics of phonological system of Albanian and can also serve for its approach to typological level.
The e-CLES project: how to make a scenario-based certificate valid, reliable and fair?

Field: Arts and Humanities (Social Sciences)

The Higher Education Language Skills Certification (French CLES) is a scenario-based language certification accredited by the French Ministry for Higher Education which is linked to the Common European Framework of Reference for Languages (CEFR). It allows students to obtain a certification to testify their skills in 11 different languages and at three different levels: CLES 1, 2, 3 corresponding respectively to levels B1, B2, C1 of the CEFR. CLES enables five language skills to be assessed: listening, reading, writing, speaking and interacting. As such it belongs to the fourth generation in the history of testing: the action-oriented integrative sociolinguistic approach (cf Spolsky 1981, Reichert, 2011, Tardieu 2013). This presentation will deal with a submitted Franco-Luxembourgian project aiming at framing the conditions for a valid, reliable and fair CLES. The project will notably involve improving the linking to the CEFR levels: The Dutch CEF Grid as well as the CEF-ESTIM grid and the expertise in standard setting gained through the Socrates EBAFLS project will be used. Key reference materials such as the SurveyLang (Cito, 2011) reports and The Manual (A.L.T.E/Council of Europe, 2011) will be solicited. The expertise of the CLES teams of testers shall be improved through the use of new criterial grids and specific tester trainings. A German and English C-Test (Raatz & Klein-Braley, 1982, Reichert, 2011), as well as additional comprehensive language tests will be used to verify the criterion validity of the CLES. Both reliability and validity of the CLES will be verified before and after the adaptation of the procedures linking the CLES to the CEFR. This will eventually allow the documentation of adequate approaches and methods helping to enhance the validity of language tests such as the CLES with regard to the CEFR.
Abstract 533: Critical role of MMP-9 dimers in cell migration: design of inhibitory peptides

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Non-proteolytic activities of matrix metalloproteinases (MMPs) have recently been shown to impact cell migration, but the precise mechanism remains to be understood. We previously demonstrated that the hemopexin (PEX) domain of MMP-9 is a prerequisite for enhanced cell migration. Using a biochemical approach, we now report that dimerization of MMP-9 through the PEX domain is necessary for MMP-9-enhanced cell migration. Following a series of substitution mutations within the MMP-9 PEX domain, two critical motifs in the outermost strands of the first and fourth blades of MMP-9 PEX domain were found to be involved in MMP-9 homo- and hetero- dimer formations. Peptides mimicking these motifs efficiently blocked MMP-9 dimer formations and inhibited MMP-9-mediated cell migration, but not membrane type 1- MMP (MT1-MMP)-induced cell migration. In addition, these peptides demonstrate inhibitory effects on migration of human fibrosarcoma HT1080 cells, which express high level of endogenous MMP-9. Using a shRNA approach, CD44 was found to be a critical molecule in MMP-9-mediated cell migration. Furthermore, a novel axis involving an MMP-9-CD44-EGFR signaling pathway in cell migration was identified using antibody microarray analysis and specific receptor tyrosine kinase inhibitors. In conclusion, we dissected the mechanism of proMMP-9-enhanced cell migration and developed structure-based inhibitory peptides specific targeting of MMP-9-mediated cell migration. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 2010 Apr 17-21; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2010;70(8 Suppl):Abstract nr 533.
Development Of Prototype Smart Door System With IoT Application

Field: Computer Science (Physical Sciences)

In this paper, the design of prototype Smart Door System with IoT Application which act as a digital door system is discussed. This paper presents the idea of controlling the lock, detecting a motion, and monitoring by live camera via a mobile application. This study is conducted to propose an enhancement to the traditional door system by utilizing the Internet of Things (IoT) technology. The bridge that we built between hardware and Internet is what we call IoT, and in this paper, Blynk application is used as the bridge for IoT.
Concurrent versus sequential neoadjuvant chemoradiation therapy for esophageal and gastroesophageal junction adenocarcinoma.

Field: Medicine (Health Sciences)

395 Background: Neoadjuvant therapy is the standard of care for locally advanced esophageal and gastroesophageal junction (GEJ) adenocarcinoma, with most patients receiving neoadjuvant chemoradiation (CRT). CRT can be delivered concurrently or sequentially after induction chemotherapy. The purpose of this study was to evaluate pathologic complete response (pCR) and overall survival (OS) among patients who received concurrent versus sequential CRT in the National Cancer Database (NCDB). Methods: Patients who received neoadjuvant CRT and underwent curative intent esophagectomy for esophageal or GEJ adenocarcinoma from 2006-2015 were included. Patients with clinical T4 or metastatic disease were excluded. Concurrent CRT was defined as radiation treatment starting within 6 weeks of chemotherapy start. Sequential CRT was defined as radiation treatment starting greater than 6 weeks after chemotherapy start. Propensity weighting was conducted to balance patient, disease, and facility covariates between groups. Results: 12,460 patients met inclusion criteria. 11,880 (95%) patients received concurrent CRT and 580 (5%) patients received sequential CRT. Patients who received sequential CRT were significantly younger (mean age: 60.7 vs 62.2 years), had higher clinical nodal stage (N2-3: 14.7% vs 10.1%), and were more often treated at academic/research hospitals (67.1 vs 55.5) (all p≤0.001). pCR was achieved in 16.2% of patients who received sequential CRT and in 14.0% of patients who received concurrent CRT (p = 0.131). Following propensity weighting, OS was significantly improved among patients who received sequential versus concurrent CRT (HR 0.82; 95% CI 0.74-0.92; p < 0.001) with a median OS for the sequential cohort of 41.4 months versus 29.4 months for those who received concurrent CRT. Conclusions: In this retrospective study from a large national database of patients who received neoadjuvant CRT for esophageal and GEJ adenocarcinoma, sequential CRT is associated with a significant OS benefit. These results merit consideration of a well powered prospective multi-institutional randomized clinical trial to further evaluate this observed difference.
Comparison Between Bivariate Phase-Rectified Signal Averaging and Sequence Method in Assessing the Baroreflex Sensitivity

Field: Medicine (Health Sciences)

Baroreflex sensitivity (BRS) measures the rate of changes in inter-beat time intervals (RR) with respect to changes in blood pressure (BP).Recently, Bivariate Phase-Rectified Signal Averaging (BPRSA) was proposed as possible BRS estimator and was compared with the validated sequence method (SM).However, the two methods differ substantially, questioning whether BPRSA might be considered as an estimator of BRS.In this study, we investigated the role that the coupling between RR, BP and respiration has on BRS estimates provided by BPRSA and SM.Multivariate autoregressive models (MVAR) were fitted to the data of 10 healthy subjects that underwent a tilt test.MVAR models were then used to generate synthetic signals while artificially varying the coupling between RR, BP and respiration.Both BPRSA and SM provided higher BRS values during supine with respect to head-up phase.Computerized simulations showed little influence of the coupling between respiration and RR on both estimators, whereas a major difference appeared when the coupling between BP and RR was removed.Then, BPRSA almost vanished, while SM increased of about 10%, regardless the phase.In conclusion, BRS estimates using BPRSA were highly dependent on the coupling between BP and RR, while SM resulted in more stable estimates.
Comparison Of The Success Rates Of The Prostaglandin E2 (PGE2) Versus Foley Catheter In Females With Postdate Pregnancy

Field: Medicine (Health Sciences)

Objective: Postdate pregnancies, defined as pregnancies that extend beyond the 40th-week gestation, are associated with an increased risk of adverse maternal and fetal outcomes. Consequently, there is a clinical need to manage these pregnancies effectively to prevent complications. Two common methods for inducing postdate pregnancies are the use of Foley catheters and prostaglandins. To determine the success rates of the Foley catheter and prostaglandin E2 (PGE2) in females with postdate pregnancy. Methods: 162 female participants were randomly divided into two groups through the lottery method. Group A utilised a Foley catheter, where after speculum examination, a 16F standard Foley catheter was aseptically inserted above the internal cervical os and inflated with 30ml of sterile water. In Group B, PGE 2 gel was administered, with nulliparous women receiving an initial dose of 2 mg per vaginum (PV) and parous women receiving 1mg PV. The gel was inserted into the posterior vaginal fornix. Success was defined as female giving within 24 hours. The data was analyzed using SPSS version 25. Results: The mean age of patients was 30.35 ± 6.89 years. Success was observed in 87(53.7%) patients, while 75(46.2%) patients did not achieve success. The study findings revealed that success was attained by 30(34.4%) individuals in group A and 57(65.5%) in group B. A statistically significant difference was observed between groups regarding the success of patients. i.e., p-value (<0.05) Conclusion: A study concludes that Prostaglandin E2 (PGE2) showed significantly higher success rates for achieving vaginal delivery within 24.0 hours when compared to Foley catheters in female individuals with postdate pregnancies. Key words: Pregnancy, Prostaglandins E2; Cervical Ripening; Pregnancy Outcome; Labour.
E-GOVERNMENT PRACTICES AND ORGANIZATIONAL PERFORMANCE IN MALAYSIA LOCAL GOVERNMENTS

Field: Social Sciences (Social Sciences)

e-Government implemented to enhance the quality and performance of services in the public sector. Malaysia faces various issues and challenges in developing e-Government, including organizational performance weaknesses. Therefore, empirical studies are important to demonstrate the impact of eGovernment on the performance of the public sector holistically and comprehensively, which is greatlyneeded to serve as input in efforts to improve the quality of e-Government. This study explores the literature on e-Government and organizational performance to see the extent of e-Government's contribution to the performance of the local government sector. To fill the research gap, an empirical study using quantitative research methods was conducted on local government in Malaysia. A total of 149 questionnaires were distributed to Local Authorities in Malaysia, and 87 questionnaires were returned. Then, the data were analysed using descriptive methodology and an inferential statistical approach. The study findings indicate that the implementation of e-Government does not have a significant impact on organizational performance. The difference results may be attributes to variationsin the e-Government development index between developed and developing countries. Additional factors such as the difference acceptance level and challenges in implementation may further affect the outcomes. Therefore, the study's findings conclude that the direct relationship is not significant. It is possible that other intermediate factors or variables exist within the relationship, which could allow for the study to be tested indirectly.
A Novel Framework for Cluster-based Sensor Fusion

Field: Computer Science (Physical Sciences)

Sensor fusion is a significant aspect for wireless sensor networks. Due to random deployment of sensor nodes, clustering and access sequence of sensor nodes will influence energy consumption and time delay of data fusion. In this paper, an energy-time-efficient framework for cluster-based data fusion is proposed for improving the performance and reducing the congestion of wireless link, which adopts maximum entropy clustering to partition wireless sensor network and engages ant colony optimization to arrange the schedule of access sequence for all sensor nodes inside clusters. In the proposed framework, a mobile agent firstly fuses local information progressively within each cluster; then central service node performs a global fusion from local results. The simulation results verify that the optimized method for cluster-based data fusion can improve the global precision. It is analyzed that the clustering can influence the efficiency and precision of data fusion. Finally, the performance of cluster-based data fusion is analyzed with the energy*time metric.
Proceedings of the 6th international conference on Web engineering - ICWE '06

Field: Computer Science (Physical Sciences)

It is our great pleasure to welcome you to the 2006 International Conference on Web Engineering.This year's conference builds on the successes of the previous ICWE conferences (ICWE'05 in Sydney, Australia, ICWE'04 in Munich, Germany, ICWE'03 in Oviedo, Spain, ICWE'02 in Santa Fe, Argentina and ICWE'01 in Caceres, Spain) in establishing ICWE as a premier venue for the presentation of research and applications in Web Engineering.This year's Call for Papers attracted 103 submissions from around the world; 44 of these were accepted as full papers and 10 as short papers. A program committee of over 100 reviewers evaluated the papers. The accepted papers span a wide range of topics, including measurement and evaluation, Web Services and service composition, security, processes and workflows, and the semantics and persistence of information, to list just a few.
A new anastomosis method for choledochojejunostomy by the way behind antrue pyloricum

Field: Medicine (Health Sciences)

Background Reflux cholangitis has been the most common complication after Roux-en-Y choledochojejunostomy. In this study we intended to evaluate the perioperative and long-term efficacy of a new anastomosis method for choledochojejunostomy. Methods Clinical data of 143 eligible patients who underwent choledochojejunostomy in the Eastern Hepatobiliary Surgery Hospital affiliated to the Second Military Medical University, China between January 2007 and December 2010 were retrospectively analyzed. Among the patients, 38 consecutive cases underwent this new anastomosis method for choledochojejunostomy (improved group, IG) and 105 underwent standard Roux-en-Y choledochojejunostomy (control group, CG). Changes in the incidence of cholangitis, the time of beginning to eat liquid meals, post-operative delayed gastric emptying and liver function between the two groups were compared. Results There was no statistical difference in the levels of alanine transaminase, alkaline phosphomonoesterase and gamma-glutamy transferase between the two groups. The time of beginning to eat liquid meals was significantly shorter in IG than CG ( P <0.05). The incidence of delayed gastric emptying was lower in IG than CG, with statistical tendency between the two groups ( P =0.052). Among nine patients with different degrees of acute cholangitis in the two groups, one patient (2.6%) in IG and eight (7.6%) in CG suffered from acute cholangitis within six months of follow-up after discharge, but with no statistical difference between the two groups ( P >0.05). Of the nine patients with acute cholangitis, none in IG and four in CG were hospitalized for further treatment ( P >0.05). Conclusions Patients in IG had satisfactory perioperative and long-term prognosis with shorter time of beginning to eat liquid meals and lower incidence of delayed gastric emptying. This new procedure of choledochojejunostomy by the way behind antrue pyloricum was easy and safe to perform with no mortality and low complication rates.
Response to Catastrophic Disasters: Toward a Network- Centered Approach

Field: Social Sciences (Social Sciences)

This research focused on the interorganizational and intergovernmental response to Hurricanes Katrina and Rita in 2005. The study used the concepts from the network and partnerships literature and used current techniques of network analysis. The study found that the use of intergovernmental and interorganizational response to coordinate complex operations in multiorganizational environments of catastrophic disasters was not successful in responding to both Hurricane Katrina and Rita in 2005. The research suggests that more investment should be made in community capacity building at the local and state levels for successful and effective partnerships in responding to catastrophic disasters. In this research, the local and state levels are shown to be faster in response and future research should focus on local, state, and federal resources coordination in response to catastrophic disasters.