jimnoneill/paper-to-field-training huggingface dataset:
DNA Nanorobot Delivers Antisense Oligonucleotides Silencing c-Met Gene Expression for Cancer Therapy

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Antisense oligonucleotides are considered to be a promising strategy for cancer therapy because of their high specificity and minimal side effects. They can bind specifically to mRNA silencing the expression of target genes. However, ssDNA cannot enter cells in large quantities, which limits its applications. Tetrahedral framework nucleic acids (tFNA) are considered to be optimal nanoscopic drug carriers because of their editability and biocompatibility. Most importantly, they can be modified with functional molecules. The over-expression of c-Met is associated with a wide variety of tumor occurrences, developments, drug resistance and prognoses. Activation of HGF/c-Met signaling pathways can promote cell migration and invasion in cancer. Therefore, blocking the expression of c-Met is a valid technique for cancer therapy. In this study, we used tFNA as carriers to deliver antisense oligonucleotides, which can bind to c-Met mRNA with high specificity and affinity, into cells resulting in the inhibition of c-Met expression for cancer therapy.
IPTEKS EDUKASI DALAM PENGAMATAN MELAKUKAN TRANSAKSI PERDAGANGAN KOMODITI BERJANGKA PADA PERUSAHAAN PIALANG PT. VICTORY INTERNATIONAL FUTURES

Field: Business, Management and Accounting (Social Sciences)

PT. Victory International Futures was established in 2003 as a brokerage company in the world financial market that uses information technology to support its business. Centered in the city of Surabaya in the heart of the Indonesian business city. PT. Victory International Futures is one of the institutions recognized by the Indonesian government. We provide 100% focus on trading via the internet using the "Meta Trader 5" system PT. Victory International Futures is under the supervision of the Commodity Futures Trading (BAPPEBTI), Member of Indonesia Commodity & Derivatives Exchanges (ICDX) / Indonesian Commodity and Derivative Exchange (BKDI) and PT. Identrust Security International (ISI). Time never stops in the era of global trade and so does PT. Victory International Futures serves thousands of customers directly and always provides quality and professional financial services.Keywords : brokerage company, gold, forex, trading system via the internet
Antecedents of privacy concerns and their online actual purchase consequences: a cross-country comparison

Field: Psychology (Social Sciences)

The paper develops a framework that shows the sequential interaction between possible causes and consequences of privacy concerns. It analyses how different levels of privacy concerns are developed and their influence on actual purchase behaviour. Theory of planned behaviour was adapted to explain the relationship between privacy concerns and online buying behaviour. Data were gathered from internet users in Egypt, UK and USA. The results indicate that online privacy concerns vary across a host of factors such as individual culture, demographic variables, internet experience, and contextual variables. Furthermore, there is significant association between privacy concerns and attitudes toward shopping online, and there is a clearly significant relationship between attitudes toward internet shopping, perceived behaviour control and actual internet purchases in all three countries.
Serial beta-hCG measurements in the early detection of ectopic pregnancy.

Field: Medicine (Health Sciences)

We investigated the sensitivity and specificity of serial serum hCG assays to diagnose early ectopic pregnancy in 50 asymptomatic women at risk. The initial two hCG values obtained at 2-5-day intervals were used to calculate doubling time and percentage increase. Twenty-five women had a viable intrauterine pregnancy, 14 an ectopic gestation, ten a spontaneous abortion, and one a molar pregnancy. A normal percentage increase and/or doubling time was observed in 64% of women who eventually proved to have an ectopic pregnancy. Ultimately, 85% of our patients demonstrated abnormal values when subsequent hCG pairs were analyzed. The sensitivity of these tests to diagnose asymptomatic ectopic pregnancy was 36%, with a specificity of 63-71%. We conclude that a normal rise in hCG production does not reliably differentiate an ectopic from an intrauterine pregnancy in the asymptomatic patient.
The Effect of a Low-Cost Body Weight-Supported Treadmill Trainer on Walking Speed and Joint Motion

Field: Health Professions (Health Sciences)

Background and Objectives: Gait training with body weight-support has been shown to improve the walking speed of individuals with movement disorders. The AccesSportAmerica Gait Trainer is a low-cost, pre-market gait rehabilitation device that alters the stride characteristics of participants walking on a standard treadmill. The purpose of this study was to examine the biomechanical outcomes that training on this device has for people with brain injuries that affect motor functioning. It was hypothesized that there would be an increase in walking speed post-intervention, and that there would be an increase in step length and joint range-of-motion. Materials and Methods: An intervention study was conducted with 11 people with ambulatory difficulty caused by post-stroke hemiparesis (n = 7), traumatic brain injury (n = 3), and cerebral palsy (n = 1). The average time using the AccesSportAmerica Gait Trainer was 34.5 (SD = 6.0) minutes per session for 36.9 (SD = 21.8) sessions. Gait speed, step length and time, and joint flexion were measured during the 10 Meter Walk Test. Results: From pre- to post-intervention, there was a mean increase in walking speed of 0.19 m/s (SD = 0.06, p = 0.016, d = 0.40) and a decrease in step time of both affected and unaffected legs (affected: p = 0.011, d = 0.37; unaffected: p = 0.004, d = 0.67). There was no significant change in stride length or joint angles. Conclusions: The AccesSportAmerica Gait Trainer has the potential to improve the walking speed of people with ambulatory difficulty.
LHD NB1arm #934829.1

Field: Physics and Astronomy (Physical Sciences)

The neutral beam (NB) shine-through profile is routinely monitored on the Large Helical Device (LHD) both to calibrate the port-through power of the NB and to evaluate the NB-deposition power to LHD plasmas. The profile is measured with a calorimeter (CM) array on an armor plate of the NB counter wall inside the LHD vacuum vessel.
Determination of high-affinity oestrogen-receptor sites in uterine supernatant preparations

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

An assay method was developed for the determination of high-affinity oestradiol receptors in uterine supernatant preparations. When only high-affinity sites are present in such preparations, or when they predominate, the analysis of the equilibrium between oestradiol and receptor sites based on the Scatchard (1949) plot may be used to determine the dissociation constant of the equilibrium and the molar concentration of the high-affinity sites. When both high-affinity and low-affinity sites are present the Scatchard plot is no longer linear and cannot be used directly to determine high-affinity sites. Determination of the reverse velocity constants of the reaction between high-affinity (k−1) and low-affinity (k−2) receptor sites and [3H]oestradiol has shown that these constants differ by at least one order of magnitude. Advantage has been taken of this difference to introduce an additional step into the assay procedure that eliminates oestradiol bound to low-affinity sites and permits the determination of high-affinity sites in different species and under a variety of physiological conditions.
A Sister Species for the Blue Crab, Callinectes sapidus? A Tale Revealed by Mitochondrial DNA

Field: Agricultural and Biological Sciences (Life Sciences)

The Atlantic blue crab, Callinectes sapidus, is acknowledged as one of the worst invasive alien species in the Mediterranean, impacting biodiversity and human activities. Native to the western Atlantic, it has expanded to European coastal waters since the early 1900s. Despite its ecological and commercial importance, genetic research on this species is limited. Here we show a comprehensive investigation of the genetic variation and evolutionary history in Callinectes sapidus using 667 mitochondrial COI gene sequences. Our dataset encompasses 36 newly generated sequences from previously understudied Mediterranean sites and 631 from worldwide locations obtained from the GenBank public database. Our findings reveal two distinct, but closely related, genetic groups within the species’ distribution range, suggesting the occurrence of a potential species complex. Furthermore, in the Mediterranean, low levels of genetic variability were observed except for substantial haplotypic differentiation in Turkish samples. This study depicts the global genetic diversity and evolutionary patterns of Callinectes sapidus, offering new insights into the taxonomic status of the species.
John McGahern’s ‘Oldfashioned’ and Anglo-Irish culture

Field: Arts and Humanities (Social Sciences)

In the short story ‘Oldfashioned’, McGahern repeats many of the tropes found in twentieth-century literary works about the Anglo-Irish. What makes this story unique, however, is that McGahern’s treatment of the Anglo-Irish is closer to that of writers from Anglo-Irish Anglican backgrounds than it is to writers from his own Catholic Nationalist background. Whereas twentieth-century Catholic Nationalist writers often subtly mock the Anglo-Irish for being out-of-touch, snobbish, and psychologically compromised by their ‘Britishness’, McGahern suggests that Anglo-Irish Anglicans are often gracious, aesthetically-minded, intellectual, and less gossipy and venally materialistic than Irish Catholics. This chapter argues that, in this, McGahern demonstrates openness to all traditions on the island and a freedom from the narrow-gauge republican perspective common to his father’s generation.
Reactions of hydrocarbons with electrophilic transition metal complexes in trifluoroacetic acid

Field: Chemistry (Physical Sciences)

The results of studies on the catalytic and stoichiometric activation of C-H and C=C bonds in hydrocarbons by electrophilic metal complexes in trifluoroacetic acid are surveyed. Reactions involving the dehydrogenation of cycloalkanes, carboxylation and oxydative carbonylation, of alkanes and aromatic compounds, oxidative coupling of aromatic hydrocarbons, oligomerisation of norbornadiene with participation of transition metal trifluoroacetates, and certain others are examined. Much attention is devoted to the conditions for the generation of active species and their nature. The bibliography includes 185 references.
Treatment of idiopathic chylothorax in 14 dogs by ligation of he thoracic duct and partial pericardiectomy

Field: Veterinary (Health Sciences)

The outcome and complications associated with thoracic duct ligation combined with partial pericardiectomy in 14 dogs with idiopathic chylothorax were investigated retrospectively. Nine of the dogs were treated in the UK and five in Italy. All of them were reassessed clinically four weeks after surgery and the respiratory function and any pleural fluid accumulation were evaluated; they were followed up by telephone contact for at least six months. Eleven of the dogs were clinically normal and had no radiographic signs of pleural effusion when reassessed after four weeks. Two showed radiographic signs of a minor accumulation of pleural fluid but were clinically normal; when reassessed after three months they showed similar radiographic signs and clinical findings; but after four months there was no evidence of pleural effusion. one dog had a major complication that required a second surgical intervention.
Paper 20: New Optical Method of Assessing Surface Quality

Field: Engineering (Physical Sciences)

A new method of assessing surface quality is described in which the light scattered from the surface is scanned by the edges of a chopper disc. The electrical output from the photocell is differentiated twice to give a signal which is a measure of the maximum rate at which the intensity of the reflected light falls off. It allows a simple, cheap, and robust instrument to be made which is insensitive to ambient illumination and can be used as a surface comparator either ‘on-line’ or as a bench instrument.
Analytic Precision in Clinical and Medical Decisions

Field: Medicine (Health Sciences)

Analytic Precision in Clinical and Medical Decisions Get access Laurence P. Skendzel, M.D. Laurence P. Skendzel, M.D. Department of Pathology Munson Medical Center Traverse City, Michigan Search for other works by this author on: Oxford Academic Google Scholar American Journal of Clinical Pathology, Volume 74, Issue 5, 1 November 1980, Page 714, https://doi.org/10.1093/ajcp/74.5.714 Published: 01 November 1980 Article history Received: 23 April 1980 Accepted: 23 May 1980 Published: 01 November 1980
Recycling carbon fibre reinforced polymers for structural applications: technology review and market outlook. Waste Manage

Field: Environmental Science (Physical Sciences)

Both environmental and economic factors have driven the development of recycling routes for the increasing amount of carbon fibre reinforced polymer (CFRP) waste generated. This paper presents a review of the current status and outlook of CFRP re-cycling operations, focusing on state–of–the–art fibre reclamation and re-manufacturing processes, and on the commercialisation and potential applications of recycled prod-ucts. It is shown that several recycling and re-manufacturing processes are reaching a mature stage, with implementations at commercial scales in operation, production of recycled CFRPs having competitive structural performances, and demonstrator com-ponents having been manufactured. The major challenges for the sound establishment of a CFRP recycling industry and the development of markets for the recyclates are summarised; the potential for introducing recycled CFRPs in structural components is discussed, and likely promising applications are investigated.
Prospects for the Development of Coconut Cooking Oil Household Business in Galang District, Deli Serdang Regency

Field: Business, Management and Accounting (Social Sciences)

Micro, small and medium enterprises (UMKM) in Indonesia have a very large and important contribution to the country's economy. UMKM currently running in the community consist of many fields, one of which is the use of Indonesian agricultural products. Coconut oil can be used as cooking oil, margarine and white butter ingredients, components in soap making and cosmetic formulations. UMKM producing coconut oil have considerable business opportunities, one of which is the Maida Coconut Cooking Oil Business which is located in Galang District, Deli Serdang Regency. The amount of coconut oil produced is still on a small scale. This is due to very simple equipment, high selling prices, and limited range of marketing strategies. This activity aims to help Maida UMKM to increase production by providing assistance in the form of tools and determining a reasonable cost of goods sold. The results showed that the cost of the product before adding equipment based on the full costing method was Rp. 41,746/L and the variable costing method was Rp. 39,236/L. Meanwhile, after adding tools based on the full costing method, it was Rp. 104,211/L and the variable costing method was Rp. 89,757/L.
Data from: Evaluation of micro-GPS receivers for tracking small-bodied mammals

Field: Agricultural and Biological Sciences (Life Sciences)

GPS telemetry markedly enhances the temporal and spatial resolution of animal location data, and recent advances in micro-GPS receivers permit their deployment on small mammals. One such technological advance, snapshot technology, allows for improved battery life by reducing the time to first fix via postponing recovery of satellite ephemeris (satellite location) data and processing of locations. However, no previous work has employed snapshot technology for small, terrestrial mammals. We evaluated performance of two types of micro-GPS (< 20 g) receivers (traditional and snapshot) on a small, semi-fossorial lagomorph, the pygmy rabbit (Brachylagus idahoensis), to understand how GPS errors might influence fine-scale assessments of space use and habitat selection. During stationary tests, microtopography (i.e., burrows) and satellite geometry had the largest influence on GPS fix success rate (FSR) and location error (LE). There was no difference between FSR while animals wore the GPS collars above ground (determined via light sensors) and FSR generated during stationary, above-ground trials, suggesting that animal behavior other than burrowing did not markedly influence micro-GPS errors. In our study, traditional micro-GPS receivers demonstrated similar FSR and LE to snapshot receivers, however, snapshot receivers operated inconsistently due to battery and software failures. In contrast, the initial traditional receivers deployed on animals experienced some breakages, but a modified collar design consistently functioned as expected. If such problems were resolved, snapshot technology could reduce the tradeoff between fix interval and battery life that occurs with traditional micro-GPS receivers. Our results suggest that micro-GPS receivers are capable of addressing questions about space use and resource selection by small mammals, but that additional techniques might be needed to identify use of habitat structures (e.g., burrows, tree cavities, rock crevices) that could affect micro-GPS performance and bias study results.
Control Effects of Three Botanical Insecticides against Erythroneura apicalis Nawa

Field: Agricultural and Biological Sciences (Life Sciences)

[Objective] The aim was to screen suitable botanical insecticides for controlling E.apicalis in Turpan region.[Method] Control effects of three kinds of botanical insecticides like Matrine,Veratridine and Pyrethrum against E.apicalis were studied.[Result]Pyrethrins had the best control effect against E.apicalis,and the control efficiency was up to 97.79% in one day and was 100% in three days,furthermore the spraying drug effect had not changed in 11 days.Matrine and Veratridine had obvious control effects against E.apicalis,and their control efficiencies were more than 50% in nine days.[Conclusion]Three kinds of medicament could be used as effective agents of prevention and control of E.apicalis.
[The catabolic patient].

Field: Medicine (Health Sciences)

Trauma and stress can cause characteristic changes in metabolism: raised lipolysis and reduced glucose tolerance as well as major renal nitrogen losses are manifestations of a postoperative or posttraumatic excess of catabolism over anabolism. Excess catabolism is caused by immobilisation and inadequate oral or parenteral nutrition. Wasting in seriously ill patients for intensive treatment. Priority must be given to the prevention of insufficiencies of organs and systems, and to the elimination of stress factors. It is only then that mobilisation and the administration of calories and nitrogen will restore a normal anabolism-catabolism balance.
Teriparatide Increases Bone Formation in Modeling and Remodeling Osteons and Enhances IGF-II Immunoreactivity in Postmenopausal Women With Osteoporosis

Field: Medicine (Health Sciences)

Abstract Transiliac bone biopsies were obtained from 55 women treated with teriparatide or placebo for 12–24 months. We report direct evidence that modeling bone formation at quiescent surfaces was present only in teriparatide-treated patients and bone formation at remodeling sites was higher with teriparatide than placebo. Introduction: Recombinant teriparatide [human PTH(1-34)], a bone formation agent for the treatment of osteoporosis when given once daily subcutaneously, increases biochemical markers of bone turnover and activation frequency in histomorphometry studies. Materials and Methods: We studied the mechanisms underlying this bone-forming action of teriparatide at the basic multicellular unit by the appearance of cement lines, a method used to directly classify surfaces as modeling or remodeling osteons, and by the immunolocalization of IGF-I and IGF-II. Transiliac bone biopsies were obtained from 55 postmenopausal women treated with teriparatide 20 or 40 μg or placebo for 12–24 months (median, 19.8 months) in the Fracture Prevention Trial. Results: A dose-dependent relationship was observed in modeling and mixed remodeling/modeling trabecular hemiosteons. Trabecular and endosteal hemiosteon mean wall thicknesses were significantly higher in both teriparatide groups than in placebo. There was a dose-dependent relationship in IGF-II immunoreactive staining at all bone envelopes studied. The greater local IGF-II presence after treatment with teriparatide may play a key role in stimulating bone formation. Conclusions: Direct evidence is presented that 12–24 months of teriparatide treatment induced modeling bone formation at quiescent surfaces and resulted in greater bone formation at remodeling sites, relative to placebo.
[Disinsertion of the left innominate vein during median vertical sternotomy (author's transl)].

Field: Medicine (Health Sciences)

The left innominate vein may be torn during median vertical sternotomy. This tear may in fact be a disinsertion of the venous trunk from the superior vena cava. Repair of this disinsertion is difficult, with a risk of stenosis. It requires the most careful technique, after dissection of the superior vena cava on either side of the tear. It is made much more simple by the use of extracorporeal circulation, which empties and collapses the superior vena cava. Finally, it may be necessary to repair this loss of substance by enlarging it with a fragment of saphenous vein.
Ipomoea sp. LOTID 293505

Field: Agricultural and Biological Sciences (Life Sciences)

Plant Genetic Resource.
Taxonomy: Ipomoea sp.
Common name(s): Sweetpotato
Conserved by: Centro Internacional de la Papa (CIP), Peru
Local sample unique identifier: LOTID 293505
Method of creation: In-house copy
Date: 2018
Other identifiers: n/a,CIP 441662
Historical: Yes
Biological status: Breeding/research material
MLS status: Included
Pointless or Powerful: The Case for Oaths of Office

Field: Arts and Humanities (Social Sciences)

The practice of making oaths comes from ancient times, a tradition common to virtually all peoples and cultures. Recent calls for ethics reform have included questions about how or whether these declarations are honored. In the fraught politics of today’s secularized, pluralistic society, skepticism about oaths may be tempting, but it is insufficient as the topic deserves critical reflection. This study assesses the efficacy of oaths of office by examining them using intellectual, aesthetic, moral, and spiritual transcendental values that define excellence. The analysis offers recommendations to reinforce the significance of this once-venerable bond between the populace and public servants.