jimnoneill/paper-to-field-training huggingface dataset:
Supplementary List 1 from Gene Signatures Associated with Mouse Postnatal Hindbrain Neural Stem Cells and Medulloblastoma Cancer Stem Cells Identify Novel Molecular Mediators and Predict Human Medulloblastoma Molecular Classification

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

<p>PDF file - 135K, List of the top-ranking genes included in the two NSC-associated gene signatures List S2 - List of the top-ranking genes included in the three different CSC-associated gene signatures</p>
‘Cultured’ Food Futures? Agricultural Power, New Meat Ontologies, and Law in the Anthropocene

Field: Social Sciences (Social Sciences)

Animal agriculture in the US and Canada is a colonial geography borne of imported ontologies of property, life, land, and food shaped by and reproducing agricultural power. This article primarily examines the ontologization of in-vitro meat (IVM) and, to a lesser degree, plant-based synthetic meat relative to our current food ontologies. IVM is positioned as the pragmatic solution to food-driven climate catastrophe in that it will supposedly allow consumers to eat meat without the ethical, environmental, safety, or health concerns associated with agriculturally produced meat. I show that arguments for and against new meat technologies pivot on ontological claims about its realness. Those in favour claim that ‘real meat’ is nothing more than a specific chemical composition that can be divorced from the animal body and current production methods. Those against IVM claim that it cannot be separated from meat as the fetishization of meat renders these technologies intelligible in the first place, and that current production methods rely on ‘livestock’ and the slaughterhouse. IVM then represents a modified form of agricultural power in which the point of application moves from the animal body to the animal cell, and synthetic meat is an articulable invention due to the material and symbolic place of animal flesh in colonial orderings of life. The regulation of these new meat technologies will likely continue to ontologize farmed animals as meat, thereby continuing dominant relationships between agricultural power and food law. I conclude by considering whether new meat technologies ought to be ontologized as food.
Rural development in the Common Agricultural Policy: correlations at regional level

Field: Social Sciences (Social Sciences)

Balanced territorial development is one of the key objectives of the rural development expenditure of the CAP. However, territorial aspects do not appear to be sufficiently considered in the policy design nor in allocation of funds. We used data on per capita EAFRD expenditures to evaluate correlations between and among NUTS2 regions. Global as well as local measures of spatial autocorrelation demonstrated a high spatial association as payments tend to be above average throughout the eastern part of the EU. The expenditure is increasingly positively associated with small farming, agricultural employment and investments, while relationship with organic production has weakened.
Institutional report - Arrhythmia Incidence and risk factors for pacemaker implantation following aortic valve replacement

Field: Medicine (Health Sciences)

Our aim was to identify the predictive factors for permanent pacemaker (PM) implantation in patients undergoing isolated aortic valve replacement (AVR). A total of 3534 patients received an AVR between January 1990 and December 2003 in our institution. Permanent PM implantation was performed in 234 (6.6%) patients, over median time of three days (range one to 24 days). This patient population was compared to a random sample of 191 patients undergoing AVR without permanent PM implantation. The overall mean age was 63.5 years (14.2) and 261 patients (62%) were male. Univariate and multivariate logistic regression analysis of pre- and perioperative data were performed. Overall the 30 days mortality was 4.2% (10y234) in patients with PM and 1% (2y191) in the control group (Ps0.046). Patients with PMs were older (P-0.001), had more additional coronary artery bypass grafting (CABG) surgery or mitral valve replacement (MVR) (P-0.001), complete right bundle branch block (RBBB) prior to surgery, and more frequently underwent re-operations compared to patients without PMs (P-0.001). The multivariate logistic regression model with PM implantation as the dependent variable demonstrated that older age was not independently associated with PM implantation. As independent predictors concomitant severe mitral valve insufficiency, CABG, subaortic stenosis (SAS) or re-do operations were identified. 2010 Published by European Association for Cardio-Thoracic Surgery. All rights reserved.
Outcomes-Based Education: Teachers’ Attitude and Implementation

Field: Social Sciences (Social Sciences)

Assessing teachers’ attitudes in the implementation of Outcomes-Based Education (OBE) is essential for the success of this new paradigm shift in the educational system. This study used a descriptive research design where the researcher gathered quantitative data utilizing a survey questionnaire to assess the attitude fostered by the teachers of the University of Bohol towards OBE. It further assessed the level of its implementation in the four major areas: formulation and alignment of learning outcomes, curriculum content and structure, teaching-learning process, and assessment. Findings of the study revealed that the respondents’ age, length of teaching experience, and highest educational attainment have no direct relationship towards OBE implementation. However, the respondents’ age is directly related to the level of its implementation. Results also revealed that teachers who have a highly favorable attitude towards OBE are more motivated and willing to carry out the overall processes that necessitate OBE implementation. For a change in education to be effective and long-lasting, teachers need to view the entire OBE process as desirable and necessary. With a strong determination and purpose combined with a collaborative effort between the school administrators, teachers, students, and other stakeholders, indeed successful implementation of this newly adopted curriculum in the higher education institutions will reach far beyond one could imagine.
Phaseolus vulgaris ECr9695

Field: Agricultural and Biological Sciences (Life Sciences)

Plant Genetic Resource.
Taxonomy: Phaseolus vulgaris
Common name(s): common bean
Conserved by: Dipartimento di scienze Agrarie Alimentari e Ambientali, Università Politecnica delle Marche (D3A-UNIVPM), Italy
Local sample unique identifier: ECr9695
Method of creation: Acquisition
Date: 2015-05-15
Historical: No
Biological status: Traditional cultivar/landrace
MLS status: SMTA transfer
Economic development and trade outcomes in East African countries: prospects and constraints

Field: Economics, Econometrics and Finance (Social Sciences)

This study employed a panel data analysis from selected East African countries, with the use of fixed and random effects model which was tested using Hausman specification test. The results from the study showed that; trade agreement and foreign direct investment (FDI) have a significant positive effect on East African economy, while trade openness exerts a negative effect as a result of low productivity. Therefore, the study recommended that the government of East African countries should embrace and develop policies in promoting the continental trade agreement and economic integration, in order to raise the level of productivity within the region and the sub-region for sustainable economic development.
Lymphocyte subpopulations in donovanosis assessed by monoclonal antibodies and immunoglobulins.

Field: Medicine (Health Sciences)

The haematological profile and peripheral blood lymphocyte subpopulations of 36 patients with donovanosis were estimated by an indirect immunofluorescence technique using monoclonal antibodies. Concentrations of serum immunoglobulins (IgM, IgG, and IgA) were also estimated. The total leucocyte and lymphocyte counts were generally raised, as were total T lymphocyte, T4, and T8 counts. Patients with the hypertrophic variant, however, had decreased numbers of T lymphocytes and T8 cells and increased B cells and IgG. B lymphocyte counts and IgM and IgG concentrations were raised generally.
Is an i-gel® supraglottic airway useful for airway rescue in the community?

Field: Health Professions (Health Sciences)

Objective: To ascertain whether an i-gel ® (Intersurgical UK) supraglottic airway is suitable for newborn resuscitation in the community. Method: Fifty five community midwives were invited to participate in this study during their continuing professional development (CPD) training time over a 4 month period. Twenty of the midwives were able to participate during this time frame. The midwives were asked to manage a newborn resuscitation scenarios using 2 differing techniques: Bag valve mask with a Guedel airway (control) and a bag with an i-gel ® . Results: Time to first breath was quicker using the i-gel ® compared to bag valve mask and Guedel airway. There was no significant difference in duration of inflation breaths between the two techniques. Participants generated higher inflation pressures using i-gel ® with a mean of 40cm H 2 O as opposed to 34cm H 2 O with the bag valve mask and Guedel airway. Conclusion: The time to first breath is considerably shorter using an i-gel ® although airway pressures were significantly higher. Further investigation is needed before it could be recommended for clinical use, specifically to investigate the increased airway pressures and the true rate of failure.
Auditory sensory range of male mosquitoes for the detection of female flight sound

Field: Neuroscience (Life Sciences)

Male mosquitoes detect and localize conspecific females by their flight-tones using the Johnston's organ (JO), which detects antennal deflections under the influence of local particle motion. Acoustic behaviours of mosquitoes and their JO physiology have been investigated extensively within the frequency domain, yet the auditory sensory range and the behaviour of males at the initiation of phonotactic flights are not well known. In this study, we predict a maximum spatial sensory envelope for flying Culex quinquefasciatus by integrating the physiological tuning response of the male JO with female aeroacoustic signatures derived from numerical simulations. Our sensory envelope predictions were tested with a behavioural assay of free-flying males responding to a female-like artificial pure tone. The minimum detectable particle velocity observed during flight tests was in good agreement with our theoretical prediction formed by the peak JO sensitivity measured in previous studies. The iso-surface describing the minimal detectable particle velocity represents the quantitative auditory sensory range of males and is directional with respect to the female body orientation. Our results illuminate the intricacy of the mating behaviour and point to the importance of observing the body orientation of flying mosquitoes to understand fully the sensory ecology of conspecific communication.
Of rights and wrongs: why China is subject to a double standard on rights

Field: Social Sciences (Social Sciences)

Abstract This chapter argues that China is subject to a double standard and explains it in detail. It briefly describes the form of Chinese nationalism with a negative feeling of resentment. It compares China to other politically unstable countries and examines the civil and political rights violations and bias against nondemocracies. It also shows a possibility of human rights policy being used for a strategy of containment. It suggests that Chinese leaders are also to be blamed for a lack of transparency and the image of China as a repressive totalitarian state. The chapter concludes that a more balanced approach on human rights issues would soften the growing politics of resentment and nationalism. It may also help negotiate a new balance of power between China and Western powers.
Depraved and Disorderly: Female Convicts, Sexuality and Gender in Colonial Australia. By Joy Damousi (New York: Cambridge University Press, 1997. x plus 221pp. $64.95/cloth $18.95/paperback)

Field: Social Sciences (Social Sciences)

Journal Article Depraved and Disorderly: Female Convicts, Sexuality and Gender in Colonial Australia. By Joy Damousi (New York: Cambridge University Press, 1997. x plus 221pp. $64.95/cloth $18.95/paperback) Get access Tamsin O'Connor Tamsin O'Connor University of New South Wales Search for other works by this author on: Oxford Academic Google Scholar Journal of Social History, Volume 32, Issue 4, Summer 1999, Pages 953–955, https://doi.org/10.1353/jsh/32.4.953 Published: 01 July 1999
Low Cell‐Wall Extensibility Can Limit Maximum Leaf Growth Rates in Rice

Field: Agricultural and Biological Sciences (Life Sciences)

The aim of this research was to clarify physiological mechanisms underlying slower leaf growth rates in rice( Oryza sativa L.) as compared with maize ( Zea mays L.) and barley ( Hordeum vulgare L). Seedlings were grown under controlled‐environment conditions with adequate supplies of water and mineral nutrients. The growth rates of emerging first leaves in both paddy and upland rice were low by comparison with maize and barley genotypes. The possibility that differences in mature cell size, comparative cell production rates, osmotic potentials, or extensibility characteristics of growing cell walls were involved in regulating these species differences were investigated. The lower growth rate of the rice leaves was not associated with comparatively lower rates of epidermal cell production but was associated with the production of smaller mature cells. The smaller size of the rice leaf cells was not associated with less negative osmotic potentials in the cell‐expansion zone. However, the comparative extensibilities of the growing leaf tissues and cell walls decreased in the order barley > maize > rice and gave good linear correlations with leaf relative‐growth rates ( r = 0.87** and 0.97**, respectively). The data suggest that exceptionally low cell‐wall extensibility is involved in limiting maximum leaf growth rates in rice. Future introduction of increased wall extensibility in paddy rice might lead to increases in leaf growth potential and conceivably to improved yields.
Multiscale Graph Neural Network for Turbulent Flow-Thermal Prediction Around a Complex-Shaped Pin-Fin

Field: Computer Science (Physical Sciences)

This study presents the development of a domain-responsive edge-aware multiscale Graph Neural Network for predicting steady, turbulent flow and thermal behavior in a two-dimensional channel containing arbitrarily shaped complex pin-fin geometries. The training dataset was constructed through an automated framework that integrated geometry generation, meshing, and flow-field solutions in ANSYS Fluent. The pin-fin geometry was parameterized using piecewise cubic splines, producing 1,000 diverse configurations through Latin Hypercube Sampling. Each simulation was converted into a graph structure, where nodes carried a feature vector containing spatial coordinates, a normalized streamwise position, one-hot boundary indicators, and a signed distance to the nearest boundary such as wall. This graph structure served as input to the newly developed Graph Neural Network, which was trained to predict temperature, velocity magnitude, and pressure at each node using data from ANSYS. The network predicted fields with outstanding accuracy, capturing boundary layers, recirculation, and the stagnation region upstream of the pin-fins while reducing wall time by 2-3 orders of magnitude. In conclusion, the novel graph neural network offered a fast and reliable surrogate for simulations in complex flow configurations.
The association of antibiotic pharmacodynamic indices with survival in human septic shock

Field: Medicine (Health Sciences)

Septic shock and sepsis associated multiple organ failure are a major cause of morbidity and mortality in intensive care units (ICUs) globally. The treatment of patients with septic shock remains one of the major challenges to ICU clinicians. In this research, 342 bacteremic patients with septic shock were determined to have been treated with a β-lactam monotherapy. Objective: To show that key pharmacokinetic indices for a wide variety of β–lactams are associated with outcome in human septic shock. Methods: β-lactam pharmacodynamic (PD) indices including time above MIC and four times above MIC (ƒT>MIC, ƒT>4X MIC). Logistic regression analysis of 1st 24 hour time above MIC (p=.0005) and 1st 24 hour time above 4X MIC (p=.0003) were strongly associated with the improved survival of septic shock. Neither the 1st 24 hour Cpeak/MIC (p=.0762) or 1st 24 hour AUC/MIC (p=.0872) achieved significance in relation to outcome in logistic regression analysis.
Development of E-Learning, Mobile Apps, Character Building, and Outdoor Study (EMCO Learning Model) to Improve Geography Outcomes in the 21st Century

Field: Social Sciences (Social Sciences)

This development study aims to 1) create a learning model that fuses e-learning, a mobile app, character building, and outdoor study and 2) determine the effectiveness of the EMCO learning model on student learning outcomes. This study uses a research and development design with the model of Dick and Carey. A product feasibility test is performed by the learning, media, and materials expert validators, and the product’s effectiveness is tested by students. The data analysis includes descriptive statistics to determine the product feasibility and an independent sample t-test to determine the effectiveness of the learning model. The results of the expert validation show that the EMCO model is in the very good category and does not need revision. The EMCO model has a learning syntax with four phases: LKPD (student worksheet), assessment instrument, learning media, and teaching materials. Results indicate that the EMCO learning model is effective in improving geography learning outcomes. The model has the advantages of 1) effective and innovative material delivery; 2) easy-to-use navigation keys to access the material; 3) attractive design; 4) availability of CBT (computer-based test); and 5) online learning media that can be accessed anytime, anywhere, and under any conditions. The research has a positive impact on students and is able to transform them into 21<sup>st</sup>-century learning agents.
Colorstock, SScolor, Ratón: RNA alignment visualization tools

Field: Computer Science (Physical Sciences)

Abstract Summary: Interactive examination of RNA multiple alignments for covariant mutations is a useful step in non-coding RNA sequence analysis. We present three parallel implementations of an RNA visualization metaphor: Colorstock, a command-line script using ANSI terminal color; SScolor, a Perl script that generates static HTML pages; and Ratón, an AJAX web application generating dynamic HTML. Each tool can be used to color RNA alignments by secondary structure and to visually highlight compensatory mutations in stems. Availability: All source code is freely available under the GPL. The source code can be downloaded and a prototype of Ratón can be accessed at http://biowiki.org/RnaAlignmentViewers Contact: ihh@berkeley.edu
Figure_S4_for_modification – Supplemental material for LKB1 and YAP phosphorylation play important roles in Celastrol-induced β-catenin degradation in colorectal cancer

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Supplemental material, Figure_S4_for_modification for LKB1 and YAP phosphorylation play important roles in Celastrol-induced β-catenin degradation in colorectal cancer by Shuren Wang, Kai Ma, Cuiqi Zhou, Yu Wang, Guanghui Hu, Lechuang Chen, Zhuo Li, Chenfei Hu, Qing Xu, Hongxia Zhu, Mei Liu and Ningzhi Xu in Therapeutic Advances in Medical Oncology
The Role and Importance of Glycosylation of Acute Phase Proteins with Focus on Alpha-1 Antitrypsin in Acute and Chronic Inflammatory Conditions

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Acute phase proteins (APPs) are a group of circulating plasma proteins which undergo changes quantitatively or qualitatively at the time of inflammation. Many of these APPs are glycosylated, and it has been shown that alterations in glycosylation may occur in inflammatory and malignant conditions. Changes in glycosylation have been studied as potential biomarkers in cancer and also in chronic inflammatory conditions and have been shown to correlate with disease severity in certain conditions. Serine protease inhibitors (serpins), many of which are also APPs, are proteins involved in the control of proteases in numerous pathways. Alpha-1 Antitrypsin (AAT) is the most abundant serpin within the circulation and is an APP which has been shown to increase in response to inflammation. The primary role of AAT is maintaining the protease/antiprotease balance in the lung, but it also possesses important anti-inflammatory and immune-modulating properties. Several glycoforms of AAT exist, and they possess differing properties in regard to plasma half-life and stability. Glycosylation may also be important in determining the immune modulatory properties of AAT. The review will focus on the role and importance of glycosylation in acute phase proteins with particular attention to AAT and its use as a biomarker of disease. The review describes the processes involved in glycosylation, how glycosylation changes in differing disease states, and the alterations that occur to glycans of APPs with disease and inflammation. Finally, the review explores the importance of changes in glycosylation of AAT at times of inflammation and in malignant conditions and how this may impact upon the functions of AAT.
A New Model of Multiple Intelligence for Teaching English Informatics in the IoT Scenario

Field: Computer Science (Physical Sciences)

This paper presents an in-depth study on the new mode of intelligent multidistance teaching of English with the help of virtual scenes of the Internet of Things. The virtual simulation technology is integrated into the traditional IoT teaching, and the professional education of IoT application technology is tapped; from the analysis of the current situation of IoT skills teaching and the feasibility of carrying out virtual simulation teaching, the “four-driven” design principle is proposed, and the teaching design is combined with the virtual simulation technology teaching, and the case design of the skill-based virtual simulation technology teaching of experience, demonstration, interaction, and assessment in the virtual environment is given. This paper presents the case design of virtual simulation teaching in a virtual environment with experience, demonstration, interaction, and assessment, and the multidimensional effect evaluation of IoT skills teaching and researches the application of virtual simulation to IoT skills teaching through the above four aspects. In this paper, a framework for distributed collaborative computing is built using an asynchronous message queue MQ, which enables multiple nodes to serve a task through task splitting. The DeepCluster module can effectively cluster the time series by deep representation learning and obtain the typical variation of time series patterns. In the task offloading module of the framework, a task offloading decision algorithm based on a value-constrained multi 0–1 backpacking model is designed to minimize task processing latency with an optimal offloading solution. The system test results show that the proposed distributed computing framework and offloading decision algorithm can significantly reduce the processing latency of large tasks.