jimnoneill/paper-to-field-training huggingface dataset:
Jet-Setting Koalas Spread Cryptococcus gattii VGII in Australia

Field: Immunology and Microbiology (Life Sciences)

Cryptococcus gattii molecular type VGII is one of the causes of cryptococcosis, a severe fungal disease that is acquired from the environment and affects many host species (including humans and koalas). In Australia, disease caused by C. gattii VGII is largely confined to western and central northern parts of the country, with sporadic cases reported in eastern Australia. We investigated an unusual case cluster of cryptococcosis, caused predominantly by C. gattii VGII, in a group of captive koalas in eastern Australia. This research identified that the movements of koalas between wildlife parks, including an initial transfer of a koala from Western Australia, introduced and subsequently spread C. gattii VGII in this captive environment. The spread of this pathogen by koalas could also impact other species, and these findings are significant in the implications they have for the management of koala transfers and captive environments.
Acoustics and psychoacoustics study of fireworks displays in two different environments: 'Fallas' in Valencia and 'Sanfermines' in Pamplona (Spain).

Field: Arts and Humanities (Social Sciences)

The different representative manifestations of the culture and traditions constitute the cultural heritage of a people. The globally extended fireworks displays are the visual and sound manifestations of traditions associated with popular culture that must be preserved. The visual component of the castle is not excessively different from one culture to another, but the sound component shows great differences, from the taste for sound power to the search for a practical disappearance of the sound that accompanies it, in direct relation to the cultural component. This paper presents a study of the different soundscapes represented by pyrotechnic fireworks in two traditional festivities in Spain. This paper presents the study carried out on the different soundscapes represented by various fireworks during two traditional festivities in Spain, both UNESCO World Heritage Sites, the Valencia "Fallas" and the Pamplona "Sanfermines", and following the ISO 12913 standard guidelines. Numerous recordings were made for the calculation of psychoacoustic parameters in accordance with the Zwicker models. The similarities and differences of the same event in different locations have been analyzed. Finally, the results of the psychoacoustic parameters have been compared with the subjective responses.
IN Botswana Supply Price for 1kg hager +2778915305 werken embalming powder in ZAMBIA,NAMIBIA Cape Town

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

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Using a digital corpus for the study of the earliest stages of Negerhollands

Field: Arts and Humanities (Social Sciences)

Abstract In this article I show three methods to use the Negerhollands computer corpus for a better understanding of the eighteenth century variety of Negerhollands. The first one is the study of metalinguistic comments which are taken up in several manuscripts. The second method is stemma/variety research between and within texts with the same content. The third method to study the do's and doubts of the first translators in order to present the right variety of the language is the analysis of annotations, changes and erasures of the writers. This philological approach was common in Medieval studies, for instance, but is hardly used with respect to Creole languages.
Ethical issues with psychedelic-assisted treatments in psychiatry: A systematic scoping review

Field: Medicine (Health Sciences)

Abstract Based on promising preliminary results from clinical trials, it seems likely that psychedelic substances (classic serotonergic psychedelics, such as psilocybin, and entactogens, such as MDMA) will be introduced into psychiatry as psychedelic-assisted therapy. This also raises a range of ethical questions that urgently need to be addressed before widespread roll-out in society. This scoping review fills a gap in the literature by providing an overview of these ethical issues using a systematic search, presentation, and descriptive analysis of ethical issues in psychedelic-assisted treatments. It includes peer-reviewed studies pertaining to human study participants and psychiatric patients (population), which discuss ethical issues (concept) of psychedelic treatments (context) in clinical trials and other clinical applications. The systematic search included several databases: MEDLINE, PsycInfo, CINAHL, HeinOnline, and PsycArticles. The search strategy, including all identified keywords and index terms, was adapted for each included database. The search was completed in June 2025 and studies published until then in any language were included. After an iterative process of inductive and deductive coding of ethical issues, the scoping review comprises seven themes related to the ethics of psychedelic-assisted treatments: (1) safety and patient well-being, (2) therapeutic relationships, (3) informed consent, (4) equity and access, (5) research ethics, (6) special contexts, and (7) societal and cultural implications. The results can be used to inform and stimulate further discussion and in-depth research on the ethics of psychedelic-assisted treatments, possibly leading to more nuanced debate surrounding a safer and more ethical implementation of psychedelic-assisted treatments in the future.
Limited, considered and sustainable consumption: The (non)consumption practices of UK minimalists

Field: Social Sciences (Social Sciences)

Minimalism is an increasingly popular lifestyle movement in western economies (predominantly in the USA, Japan and Europe) that involves voluntarily reducing consumption and limiting one’s possessions to a bare minimum. This is with the intention of making space for the ‘important’ (potentially immaterial) things that are seen to add meaning and value to one’s life. Drawing on interviews with minimalists in the UK, this article reveals that minimalists practice sustainable (non)consumption via limiting their consumption. This is achieved by actively buying less, using up and maintaining what is owned, and, when objects are acquired, only practising highly intentional, considered and (sometimes) ethical consumption. For some, such practices are predominantly based on strong ethical and environmental motivations or are seen as a positive ‘by-product’ of their minimalist lifestyles. Whilst for others, their motivations are primarily aligned to personal well-being. The article subsequently argues that the limited and considered practices of minimalist consumption can be seen as sustainable practices in outcome, if not always in intent.
Root system and yield of sugarcane cultivated under different amounts of straw in southern Brazil

Field: Agricultural and Biological Sciences (Life Sciences)

The amount of straw of sugarcane needed to remain in field for sustainability of the production system and quantity that could be used in sectors such as cogeneration and production of bioethanol for optimization of power generation by the sector are unclear issues. The aim of this study was to evaluate the effect of different amounts of straw on the development of the sugarcane root system and yield using the variety SP 801816 in a Rhodic Eutrudox in southern Brazil. Six treatments were evaluated: 0 (no straw), 25, 50, 75 and 100% (20 Mg ha-1) of straw and straw burned at 60, 180 and 270 days after planting in 150 m2 plots. Root samples were collected at 0.45 and 0.75 m from the planting line at depths of 0-0.10, 0.10-0.20, 0.20-0.40 and 0.40 to 0.60 m at harvest, and the stems of the plots were weighed to measure yield. In water stress period, the 50, 75 and 100% straw treatments promoted a greater root mass to 0.20 m deep, which was also reflected in the yield. The 50 and 75% straw treatments resulted in 25% greater yield than the 0 and 25% straw and straw burned, resulting in 28 Mg ha-1 more. The amount, 50% straw retention in the field is sufficient to increase the mass of the roots and, in turn, productivity, which is possible to remove the 50% surplus from the field for industrial processes for the production of energy, without the occurrence of damage to the crop. Key words: Green cane, biomass, mechanized harvesting, agricultural waste, Saccharum spp.
Modelling and observations of the katabatic flow dynamics over Greenland

Field: Earth and Planetary Sciences (Physical Sciences)

The katabatic wind system over the Greenland ice sheet is studied using simulations of the hydrostatic Norwegian Limited Area Model (NORLAM) and measurements of an instrumented aircraft. The structure and the dynamics of the katabatic wind over the ice sheet are investigated for a case study of the aircraft-based experiment KABEG (Katabatic wind and boundary layer front experiment around Greenland) in the area of southern Greenland in April/May 1997. Monthly mean Structures and individual contributions of the momentum budget integrated over the boundary layer are examined for one winter month. The NORLAM is able to simulate realistically the Structures of the katabatic wind system in the lowest 400 in. The comparison with KABEG aircraft measurements for a katabatic wind case with strong synoptic forcing shows good agreement for the momentum budget terms. The pure katabatic force represents the main mechanism for the boundary layer wind field. but a considerable influence of the large-scale synoptic forcing is found as well. Acceleration components from the NORLAM forecasts are also presented for the whole month of January 1990. The monthly mean fields show significant regional differences because of different inversion strengths and synoptic forcings. In particular. Southeast Greenland is influenced by transient synoptic cyclones and the associated cloud patterns. All other areas of the slopes of the Greenland ice sheet are characterized by a downslope katabatic acceleration. The pressure gradient force over the northwestern part of the Greenland ice sheet points in the direction of the local katabatic force, which explains the relatively strong monthly mean near surface winds over the ice. Over the southwestern and northeastern parts of Greenland, however, no significant synoptic support of the katabatic winds is present, and the synoptic pressure gradient is even opposed to the katabatic force in some regions.
EFEK PEMBERIAN MULTI MICRO NUTRIENT (MMN) DAN KONSELING GIZI TERHADAP STATUS GIZI WANITA PRAKONSEPSI

Field: Health Professions (Health Sciences)

The preconception period is the time before pregnancy, during which preconception women are assumed to be adult women or women of childbearing age ready to become mothers, where nutritional needs during this period differ from those of children, adolescents, or the elderly. Pre-marital women suffering from undernutrition can lead to anemia, maternal death during childbirth, fetal death, low birth weight babies (LBW), premature birth, birth defects, and infant death. This study aims to examine the relationship between the nutritional status of preconception women and the consumption of Multiple Micronutrient Supplementation (MMN), nutritional counseling involvement, and the frequency of nutritional counseling attendance.The study design is cross-sectional. The population consists of all preconception women who meet the inclusion criteria in the Batui Selatan district. The sampling technique used purposive sampling, and the study was conducted from October to December 2023. Data collection used a questionnaire to determine MMN consumption and involvement in nutritional counseling, nutritional status was assessed by measuring height, weighing, and measuring mid-upper arm circumference. The analysis used univariate and bivariate, using the Chi-Square test. The results showed that there was a significant relationship between the nutritional status of preconception women and the level of MMN consumption (P=0.001), and nutritional status with attendance in nutritional counseling (P=0.005). this it can be concluded that MMN consumption and nutritional counseling affect the nutritional status of preconception women.
Measurement, modeling, and prediction of temperature rise due to optogenetic brain stimulation

Field: Neuroscience (Life Sciences)

Optogenetics is one of the most important techniques in neurophysiology, with potential clinical applications. However, the strong light needed may cause harmful temperature rises. So far, there are no methods to reliably estimate brain heating and safe limits in actual optogenetic experiments. We used thermal imaging to directly measure such temperature rises at the surface of live mouse brains during laser illumination with wavelengths and intensities typical for optogenetics. We then modeled the temperature rise with a simple logarithmic model. Our results indicate that previous finite-element models can underestimate temperature increases by an order of magnitude. We validate our empirical model by predicting the temperature rise caused by pulsed stimulation paradigms. These predictions fit closely to the empirical data and constitute a better estimate of real temperature increases. Additionally, we provide a web-based app for easy calculation that can be used as a tool for safe design of optogenetic experiments.
Effectiveness of Lithium Carbonate in the Treatment of Manic-Depressive Illness

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The author reports on the responses to lithium cabonate of 75 manic-depressive patients. Lithium carbonate was found to be highly effective in the acute manic state but without merit in the treatment of acute depression. Its efficacy was inversely related to age. Response to the drug varied in some patients; a positive response at one time was no guarantee for a similar response in subsequent trials. The possibility of different biochemical states underlying similar clinical states is discussed.
HIV Revisited: The Global Impact of the HIV/AIDS Epidemic

Field: Medicine (Health Sciences)

This review is intended as an update on modern trends in the global impact and epidemiology of human immunodeficiency virus infection for physicians who are not acquired immunodeficiency syndrome experts. Africa has been the most affected, but epidemics are spreading in Asia and Russia. Therefore, physicians should be informed about seroconversion disease and human immunodeficiency virus diagnosis as well as the impact of sexually transmitted infections on many stages of human immunodeficiency virus. International treatment guidelines are available. Highly active antiretroviral therapy has been the mainstream therapy since 1996, but all drugs—regardless of class used—have potent side effects, many of which are dermatologic. Others affect the neurologic, hematopoietic, cerebral, and abdominal systems, and drug interactions are common. Lipodystrophy is a common, long‐term side effect that is still not well understood. Broader use of highly active antiretroviral therapy has highlighted viral resistance. This is reviewed, and a simple explanation of therapeutic monitoring is provided.
Navigating Incommensurability Between Ethnomethodology, Conversation Analysis, and Artificial Intelligence

Field: Arts and Humanities (Social Sciences)

Like many research communities, ethnomethodologists and conversation analysts have begun to get caught up -- yet again -- in the pervasive spectacle of surging interests in Artificial Intelligence (AI). Inspired by discussions amongst a growing network of researchers in ethnomethodology (EM) and conversation analysis (CA) traditions who nurse such interests, I started thinking about what things EM and the more EM end of conversation analysis might be doing about, for, or even with, fields of AI research. So, this piece is about the disciplinary and conceptual questions that might be encountered, and -- in my view -- may need addressing for engagements with AI research and its affiliates. Although I'm mostly concerned with things to be aware of as well as outright dangers, later on we can think about some opportunities. And throughout I will keep using 'we' to talk about EM&CA researchers; but this really is for convenience only -- I don't wish to ventriloquise for our complex research communities. All of the following should be read as emanating from my particular research history, standpoint etc., and treated (hopefully) as an invitation for further discussion amongst EM and CA researchers turning to technology and AI specifically.
The Texture of Traumatic Attachment: Presence and Ghostly Absence in Transgenerational Transmission

Field: Psychology (Social Sciences)

Work on the transgenerational transmission of trauma refers to unspoken stories across generations, but the actual mode of transmission has remained somewhat mysterious. Utilizing examples from her own life, the author illustrates how attachment patterns are a primary mode of transmission of trauma. When trauma revisits a person transgenerationally through dysregulated and disrupted attachment patterns, it is within the child's empathic attunement and search for a parental bond that the mode of transmission can be found. This will become the texture of traumatic attachment: how it feels to this child to feel connected to the parent.
Structural and biochemical studies of substrate recognition and allostery in aPKCι and PKN2

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The AGC family of protein kinases (related to protein kinases A, G and C) are a functionally and structurally distinct class of eukaryotic kinases that phosphorylate serine/threonine residues within their substrates. AGC kinases are implicated in diverse biological processes but mechanisms generating substrate specificity remain unclear. Protein kinase substrates can be recognised through sequences proximal to the phospho-acceptor, distal docking motifs or subcellular co-localisation by associated scaffold proteins. Peptide libraries revealed that AGC kinases target a basophilic (R-X-X-S/T-ψ) consensus but the contribution of distal docking motifs towards their substrate recognition, remains poorly understood. This thesis investigates structural features implicated in substrate recognition and allostery, in two related human AGC kinases; the atypical PKC (aPKC) isoform iota (PKCι) and protein kinase novel isoform 2 (PKN2), primarily using crystallographic and biochemical methods. The docking role of the FXR (Phe-X-Arg) motif, present in many cell polarity substrates of aPKC was investigated. This study supports the docking role of the FXR motif, reveals a novel allosteric pocket in the PKCι kinase domain, whilst collaborative studies in silico and in vivo indicate a broader role of the motif in polarity substrates of aPKC. Crystallographically defined allosteric pockets within the kinase domain of PKCι, were targeted in a search for small molecule ligands, including a high throughput compound library screen. The first structure of a substrate peptide bound to the PKN2 kinase domain is reported, revealing a novel peptide binding trajectory, engaging the conserved but poorly understood RYPR (Arg-Tyr-Pro-Arg) motif. This structure and preliminary biochemical data, explain the previously observed S312 phospho-acceptor preference of PKN2 in the CLIP1 protein, point to a RYPR mediated substrate docking PKN2 kinase domain dimer and suggest an extensive CLIP1-PKN2 interface potentially regulated by S755 phosphorylation in PKN2.
Arteriogenesis in mouse hindlimb following ischemia and growth factor therapy

Field: Medicine (Health Sciences)

The restoration of blood flow following occlusion of a major artery occurs through the development of new collaterals. The commonly used histological determination of capillary density only provides semi‐quantitative measure of vessels in a limited tissue area and without confirming their perfusion functionality. The quantitative assessment of arteriogenesis in small animal models has not been possible. In this study, a high resolution micro‐CT imaging was used to study arteriogenesis in the mouse model of hindlimb ischemia, and to examine the effects of growth factor therapy on this processes. Three dimensional micro‐CT and quantitative image analysis showed that ligation of femoral artery resulted in the increase in the number of vessels ranging from 8 to 160 μm in diameter. More importantly, the increase in the volume of medium size vessels, ranging from 48–160 μm, was the major contributor to the vascular change in response to ischemia. Collateral vessels originating near the ligation site in the upper limb and connecting to the ischemic calf muscle region became prominent and remained stable until the end of study (4 weeks). Intramuscular PIGF gene delivery using adenoviral vector significantly increased Sca1 + cells in the circulation and the volume of collateral vessels in the ischemic hindlimb. These results for the first time show that an increase in the vascular volume of medium size vessels is a major contributor to the restoration of blood flow following ischemia. PIGF selectively enhanced the medium size vessels suggesting its therapeutic potential for induction of arteriogenesis in ischemic coronary and peripheral arterial disease.