jimnoneill/paper-to-field-training huggingface dataset:
doi:10.1155/2011/282503 Research Article A Population-Based Study of Peyronie’s Disease: Prevalence and Treatment Patterns in the United States

Field: Medicine (Health Sciences)

Copyright © 2011 Dana Britt DiBenedetti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Purpose. To estimate the US prevalence of Peyronie’s disease (PD) from patient-reported data and to identify diagnosis and treatment patterns. Methods. 11,420 US males ≥18 years old completed a brief web-based survey regarding the presence of PD, past treatments, and penile symptoms (Phase 1). Phase 1 respondents with PD diagnosis, history of treatment, or PD-related symptoms then completed a disease-specific survey (Phase 2). Results. Estimated prevalence of PD ranged from 0.5 % (diagnosis of PD) to 13 % (diagnosis, treatment, or penile symptoms). Thirty-six percent of Phase 2 participants reported that penile symptoms interfered with sexual activities. Of participants who sought treatment for penile symptoms (n = 128), 73 % initially saw a primary care physician, 74 % did not receive treatment from their first doctor, and 92 % were not diagnosed with PD. Conclusions. PD may be underdiagnosed/undertreated in the US. Improved awareness is needed of PD symptoms and treatment options among health care professionals. 1.
Stability Theory via Liapunov's Method: A Note on the Contribution of Takuma Yasui

Field: Arts and Humanities (Social Sciences)

Research Article| November 01 1987 Stability Theory via Liapunov's Method: A Note on the Contribution of Takuma Yasui E. Roy Weintraub E. Roy Weintraub Search for other works by this author on: This Site Google History of Political Economy (1987) 19 (4): 615–620. https://doi.org/10.1215/00182702-19-4-615 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation E. Roy Weintraub; Stability Theory via Liapunov's Method: A Note on the Contribution of Takuma Yasui. History of Political Economy 1 November 1987; 19 (4): 615–620. doi: https://doi.org/10.1215/00182702-19-4-615 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsHistory of Political Economy Search Advanced Search The text of this article is only available as a PDF. Copyright © 1987 by Duke University Press1987 Article PDF first page preview Close Modal You do not currently have access to this content.
Surgical-pharmacological interactions in the treatment of acromegaly

Field: Medicine (Health Sciences)

Continuing efforts at improving surgical techniques and at generating more efficacious pharmacological therapies for acromegaly are likely to improve the outcome of these patients. However, an integral approach of the patient aimed not only at achieving biochemical criteria of cure but also at treating the individual comorbidities is mandatory to improve the quality of life of these patients and to reduce their mortality rate.
An illustration of the development of a strategy for evaluating the design of hospitals within a practice order network

Field: Health Professions (Health Sciences)

This conference paper was presented at the 30th Annual ARCOM Conference held on the 1st-3rd September 2014, in Portsmouth. It was originally published at: http://www.arcom.ac.uk/-docs/proceedings/ar2014-1263-1272_OKeeffe_Thomson_Dainty.pdf
Nonlocal density correlations as a signature of Hawking radiation from acoustic black holes

Field: Physics and Astronomy (Physical Sciences)

We have used the analogy between gravitational systems and nonhomogeneous fluid flows to calculate the density-density correlation function of an atomic Bose-Einstein condensate in the presence of an acoustic black hole. The emission of correlated pairs of phonons by Hawking-like process results into a peculiar long-range density correlation. Quantitative estimations of the effect are provided for realistic experimental configurations.
Anthracycline-based preoperative chemotherapy plus lapatinib and trastuzumab or both in HER2-positive breast cancer: Preliminary cardiac safety report of the CHER LOB trial

Field: Medicine (Health Sciences)

573 Background: The combination of anthracyclines and anti-HER-2 agents is highly active in HER-2 positive breast cancer, but its use is limited by an enhanced risk of cardiac toxicity. We are running a randomized phase II trial of combined preoperative chemotherapy (CT) with anthracycline plus trastuzumab, lapatinib, or both in HER-2 positive stage II-IIIA breast cancer patients. Aims of the study are the percentage of pathological complete response (pCR = breast + axillary nodes) and cardiac safety. We report the updated cardiac safety and activity data following the IDMC recommendation to continue study accrual. Methods: CT consists of sequential paclitaxel (P) 80 mg/m 2 weekly for 12 weeks followed by 4 courses of FE 75 C administered every 3 weeks. Arm A is CT + trastuzumab 2 mg/kg weekly; arm B is CT + lapatinib 1500 mg po daily; arm C is CT + trastuzumab 2 mg/kg weekly + lapatinib 1,000 mg po daily. Both trastuzumab and lapatinib are started concomitantly with the first P administration, and are administered throughout the duration of CT. Left ventricular ejection fraction (LVEF) is evaluated at baseline, before the start of FE 75 C, and at the completion of treatment. The planned sample size is 120 patients, and has been calculated according to the two steps Simon's design. Results: 53 out of the 120 planned patients have been randomized: 16 in arm A, 17 in arm B, and 20 in arm C. Median age is 48 years (range 27–66). The mean LVEF was 63% (range 54–77%) at baseline, 61% (50–78%) at the completion of weekly P + trastuzumab, lapatinib, or trastuzumab + lapatinib, and 60.3% (54–74%) at the completion of the whole treatment plan. Thirty patients underwent surgery: 19 patients (63%) received breast conserving surgery; 13 patients (43%) achieved a pCR. Conclusions Following the updated interim analysis, the combination of T, L or both with an anthracycline-containing regimen is feasible, with very interesting level of activity. The next planned analysis will be performed when 60 patients will be evaluable and will be presented at the Meeting. [Table: see text]
The Study on Apolipoprotein E Gene Polymorphism Characteristics of Cerebral Infarction and Intracerebral Hemorrhage

Field: Medicine (Health Sciences)

Objective To study the apo-E gene polymorphisms and the lipoprotein level character of different gene expression in patients with cerebrovascular infarction(CI) and intracerebral hemorrhage(ICH).Methord With case-control study method,the apo-E gene expression,its allele frequency and the levels of serum lipids in patients with cerebrovascular infarction or with intracerebral hemorrhage and the control were compared.Result The CI group had a higher apo-E e4 allele frequency(10%) than controls(4.6%)(P0.05).The levels of TC and LDL-c were higher,and HDL-c was lower in CI group with e2 and e4 allele than that in ICH group.But the level of TG in CI group with e4 allele was significant higher than that in controls(P0.05).Conclusion Apo-E e4 allele is a genetic susceptible factor for CI.The gene polymorphism of apo-E wasn't associated with ICH.Apo-E could increase the risk of CI through influencing the metabolism of serum lipids.
Accuracy of Self-Reported Breast Cancer Information among Women from the Ontario Site of the Breast Cancer Family Registry

Field: Medicine (Health Sciences)

Obtaining complete medical record information can be challenging and expensive in breast cancer studies. The current literature is limited with respect to the accuracy of self-report and factors that may influence this. We assessed the agreement between self-reported and medical record breast cancer information among women from the Ontario site of the Breast Cancer Family Registry. Women aged 20–69 years diagnosed with incident breast cancer 1996–1998 were identified from the Ontario Cancer Registry, sampled on age and family history. We calculated kappa statistics, proportion correct, sensitivity, specificity, and positive and negative predictive values and conducted unconditional logistic regression to examine whether characteristics of the women influenced agreement. The proportions of women who correctly reported having received a broad category of therapy (hormone therapy, chemotherapy, radiation, or surgery) as well as sensitivity and specificity were above 90%, and the kappa statistics were above 0.80. The specific type of hormonal or chemotherapy was reported with low-to-moderate agreement. Aside from recurrence, no factors were consistently associated with agreement. Thus, most women were able to accurately report broad categories of treatment but not necessarily specific treatment types. The finding of this study can aid researchers in the use and design of self-administered treatment questionnaires.
Pex13p Is an SH3 Protein of the Peroxisome Membrane and a Docking Factor for the Predominantly

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract. Import of newly synthesized PTS1 proteins into the peroxisome requires the PTS1 receptor (Pex5p), a predominantly cytoplasmic protein that cycles between the cytoplasm and peroxisome. We have identified Pex13p, a novel integral peroxisomal membrane from both yeast and humans that binds the PTS1 receptor via a cytoplasmically oriented SH3 domain. Although only a small amount of Pex5p is bound to peroxisomes at steady state (&lt;5%), loss of Pex13p fur-C OMPARTMENTALIZATION of proteins within subcellular organelles is a hallmark of eukaryotic cells. Accordingly, eukaryotic cells have developed mechanisms for recognizing newly synthesized organellar proteins and directing them to their proper destination. In the
Comparison of inherited neural tube defects in companion animals and livestock

Field: Veterinary (Health Sciences)

Abstract Neural tube defects (NTDs) are congenital malformations resulting from the improper or incomplete closure of the neural tube during embryonic development. A number of similar malformations of the protective coverings surrounding the central nervous system are also often included under this umbrella term, which may not strictly fit this definition. A range of NTD phenotypes exist and have been reported in humans and a wide range of domestic and livestock species. In the veterinary literature, these include cases of anencephaly, encephalocele, dermoid sinus, spina bifida, and craniorachischisis. While environmental factors have a role, genetic predisposition may account for a significant part of the risk of NTDs in these animal cases. Studies of laboratory model species (fish, birds, amphibians, and rodents) have been instrumental in improving our understanding of the neurulation process. In mice, over 200 genes that may be involved in this process have been identified and variant phenotypes investigated. Like laboratory mouse models, domestic animals and livestock species display a wide range of NTD phenotypes. They remain, however, a largely underutilized population and could complement already established laboratory models. Here we review reports of NTDs in companion animals and livestock, and compare these to other animal species and human cases. We aim to highlight the potential of nonlaboratory animal models for mutation discovery as well as general insights into the mechanisms of neurulation and the development of NTDs.
Suitability of Pollen from Different Plant Species as Alternative Food Sources for Neoseiulus californicus (Acari: Phytoseiidae) in Comparison with a Natural Prey

Field: Agricultural and Biological Sciences (Life Sciences)

Alternative foods such as pollen may help predators to maintain their populations even when their prey is scarce or absent. In order to develop an appropriate spider mite management strategy using Neoseiulus californicus McGregor and optimize laboratory rearing, its biological parameters on four types of pollen (cedar, pistachio, pear, and apricot) were determined and compared on Tetranychus urticae Koch. Our results indicated that the developmental times of females and males varied from 6.06 to 7.32, and 6.00 to 7.15 d, respectively. The highest fecundity was obtained on pistachio pollen, followed by apricot pollen and T. urticae. Feeding on cedar pollen caused the lowest fecundity. In contrast to T. urticae and pistachio pollen, which resulted in the highest intrinsic and finite rates of increase, feeding on cedar pollen produced the lowest value. Pistachio and apricot pollen appear to have the highest nutritional value. From an ecological perspective, in the presence of pistachio pollen, a more rapid population increase of N. californicus could be expected, when the prey is scarce or absent in greenhouses or fields. This may provide valuable information for the design of a comprehensive program for conservation and/or mass production of N. californicus to control T. urticae and other pests.
Challenges of negotiating obesity‐related findings with African migrants in Australia: Lessons learnt from the African Migrant Capacity Building and Performance Appraisal Project

Field: Health Professions (Health Sciences)

Abstract Aim: To document sub‐Saharan African migrants' and teachers' reaction to and acceptance of findings from African Migrant Capacity Building and Performance Appraisal initiative, and to examine the implications for any community‐based obesity prevention program. Methods: Two community forums were organised to discuss the research findings: one with 45 African community leaders from various African communities in Melbourne; and the other with 17 primary and secondary teachers from English Language Schools and Centres across Victoria. The dissemination focused on highlighting the rapid weight gain and obesity risks observed among African migrant children. Results: Sub‐Saharan African migrants' reaction to the findings was that of pride and satisfaction with large body size, seeing it as a job well done, reflecting their perceptions that obesity is not a disease. In addition, they highlighted the intergenerational conflict related to body size ideals between parents and teenage offspring, with the latter preferring model‐like Australian body sizes. Conclusion: Further research is required to examine the association between shifting preferences in body ideals and obesity among traditional communities, such as sub‐Saharan African migrants. The understanding of how changes in body image perceptions may influence eating and exercise behaviours among sub‐Saharan African migrants would assist in the development of obesity‐related preventive interventional programs for this at‐risk population.
Intelligent Character System using Emotion Metadata

Field: Computer Science (Physical Sciences)

최근 IT와 네트워크 기술이 발전하고, 유무선 네트워킹을 통한 개인 간 교류가 매우 활성화됨에 따라, 개인의 개성과 감성을 잘 표현할 수 있는 시스템이 각광 받고 있다. 특히 휴대인터넷이 발달하면서 모바일을 중심으로 개인화된 시스템에 대한 요구가 증가하고 있다. 이에 발맞추어 사용자의 감성을 표현하는 지능형 캐릭터시스템을 감성인자 메타데이터 검색방법으로 구현하였다. 이 검색방법은 감성인자 근접도 측정을 통해 다양한 감성표현을 가능하게 함으로써 텍스트 기반의 기존 검색방식을 보완하고 개인의 감성을 표현하는 툴로 유용하게 사용될 수 있으며 지능형 캐릭터 시스템은 모바일 단말기에 탑재되어 다양한 서비스에 활용될 수 있을 것이다. As the information and the network technology are improved, the system which can express the interactions between the individuals becomes to play more important roles in these days. In fact, that tendency is especially well shown in the community area of P2P and social network service programs. This paper suggest an intelligent character manipulation system which can be effectively used to express emotional representation in an intelligent way in spite of many constraints. The system employs an emotion searching mechanism by attaching emotional information to each object in the database and defining a function of emotional similarity. It is expected that the system can be successfully used not only to find and represent the suitable emotional character representations but also to provide brand new services in the area of mobile platform based contents.
A spatially explicit study of prey–predator interactions in larval fish: assessing the influence of food and predator abundance on larval growth and survival

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract We apply a coupled biophysical model to reconstruct the environmental history of larval radiated shanny in Conception Bay, Newfoundland. Data on the larvae, their prey and predators were collected during a 2‐week period. Our goal was to determine whether environmentally explicit information could be used to infer the characteristics of individual larvae that are most likely to survive. Backward drift reconstruction was used to assess the influence of variations in the feeding environment on changes in the growth rates of individual larvae. Forward drift projections were used to assess the impact of predators on mortality rates as well as the cumulative density distribution of growth rates in the population of larvae in different areas of the bay. There was relatively little influence of current feeding conditions on increment widths. Patterns of selective mortality indicate that fast‐growing individuals suffered higher mortality rates, suggesting they were growing into a predator's prey field. However, the mortality rates appeared to increase with decreasing predator abundance, based on the drift reconstructions. The relationship of growth and mortality with environmental conditions suggests that short‐term, small‐scale variations in environmental history may be difficult to describe accurately in this relatively small system (∼1000 km 2 ).
Regional Sediment Analysis of Mississippi River Sediment Transport and Hydrographic Survey Data

Field: Environmental Science (Physical Sciences)

The cumulative impacts of human occupation and development of watersheds, combined with engineering works on river channels have significantly disrupted the dynamic equilibrium of many stream systems and ecosystems. Sediments generated through channel instability are carried downstream to cause sedimentation problems in flood control channels, destroy wetlands and lakes, adversely impact fish and wildlife habitats, degrade water quality, adversely impact infrastructure. In extreme cases, sedimentation itself may initiate further accelerated stream instabilities. The Corps of Engineers attempt to design channel systems on a regional basis, particularly with respect to sediment management. Progress is hampered because there is little published guidance for accomplishing effective regional sediment management and a shortage of reliable and comprehensive data sets with which to investigate and understand sediment dynamics at the regional scale. Compilation of historical and contemporary data on sediment transport rates, sediment load and bed material particles sizes, channel morphology and engineering interventions along the Lower Mississippi River provides a data set of unparalleled value in Regional Sediment Analysis. In this report, the potential of the data to support regional analysis of sediment transfer, morphological response and the identification of causal links between engineering and sediment problems at a variety of scales is examined.
<title>Analysis and testing of a Mach-scaled helicopter rotor in hover with piezoelectric bender-actuated trailing-edge flaps</title>

Field: Engineering (Physical Sciences)

This paper presents an analytic model and validation tests of Froude and Mach scaled rotors featuring piezoelectric bender actuated trailing-edge flaps for active vibration suppression. A finite element structural formulation in conjunction with time domain unsteady aerodynamics is used to develop the rotor blade and bender-flap coupled response in hover. The analysis accounts for the aerodynamic, centrifugal, inertial and frictional loads acting on the coupled bender-flap-rotor system in hover. To investigate the feasibility of piezo-bender actuation and validate the analytic model, a 6 foot diameter, two-bladed Froude scaled rotor with piezo-bender actuation is tested on the hover stand. Flap deflections of +/- 4 to +/- 8 degrees, for 1 to 5 /rev bender excitation were achieved at the Froude scaled operating speed of 900 RPM. The trailing-edge flap activation resulted in a 10% variation in the rotor thrust levels at 6 degrees collective pitch. The analytic model shows good correlation with experimental flap deflections and oscillatory hubloads for different rotor speeds and collective settings. Based on the analytic model, two Mach scaled rotor blades with piezo-bender actuation are designed and fabricated. To achieve the desired flap performance at Mach scale, an 8-layered, tapered bender is fabricated. The bender performance is further improved by selectively applying large electric fields in the direction of polarization for individual piezoceramic elements. A radial bearing is incorporated to reduce frictional loads at the blade-flap interface. Preliminary testing of the Mach scaled blades at 900 RPM in a vacuum chamber revealed negligible degradation in flap performance because of centrifugal and frictional loading. The analysis predicts that flap deflections of +/- 5 to +/- 10 degrees for 1 to 4 /rev bender excitation can be achieved at the Mach scaled operating speed of 2100 RPM. Future work will involve hover and wind tunnel testing at Mach scaled operating speeds.
JA’s Sanctuary

Field: Economics, Econometrics and Finance (Social Sciences)

This chapter evaluates strategic reform in rice-centric co-ops—those that produce and market more rice than any other product. It illustrates how the measuring rod of price wields its influence over the reform process differently than in co-ops with more diverse product lines, and for one simple reason: rice prices have been declining over the last generation. The chapter then analyzes two co-ops from Niigata Prefecture: JA Uonuma Minami and JA Echigo Jōetsu. It argues that, to do well, reformist rice-centric co-ops with a competitive product and strong farmer organizations must not only satisfy certain resource and market, organizational, and agency conditions but also place a premium on the timing of their reforms and on the co-op's acquisition of sophisticated marketing skills. The chapter also explains why even hardworking, reform-oriented co-ops in today's challenging rice market may fail to stabilize farmer incomes, let alone increase them.
Pragmatism and the Ideal Language

Field: Arts and Humanities (Social Sciences)

Pursuing a line of progression articulated by Prof. Quine, Dr. Pasch ( Experience and the Analytic ) argues that the analytic-synthetic distinction rests on mere convention. Further, that the use of this distinction by present day empiricists—especially the rational reconstructionists—has caused empiricism to take a departure from traditional empiricism. I observe, in opposition, 1) the natural language firmament is itself an amorphous construct, 2) the natural language might be the language of experience but not of empiricism, 3) the ideal language is tied to experience by primitives for what perceptually appears, and 4) if one claims the primitives must be tested in scientific inquiry, a case should be made for this philosophical position.
Bee Swarm Optimization in Model Specification Search: A Simulation Study

Field: Psychology (Social Sciences)

This study extends the Bee Swarm Optimization (BSO) algorithm for model specification search in psychological test construction by adapting it from bifactor to correlated factor models. Using simulation studies under varying structural complexities and noise conditions, the performance of BSO was evaluated using multiple optimization criteria, including global and local model fit, and item retention. The results demonstrate that BSO consistently identifies an optimal model across all conditions, even with a small number of seeds. This data-driven method offers a promising alternative to traditional item selection methods, contributing to the refinement of measurement model development.