jimnoneill/paper-to-field-training huggingface dataset:
Paclitaxel Versus Sirolimus Stents in Diabetic and Nondiabetic Patients

Field: Medicine (Health Sciences)

Background— Drug-eluting stents are more effective in reducing restenosis than bare-metal stents. Less certain is the relative performance of 2 widely used drug-eluting stents—sirolimus- and paclitaxel-eluting stents—in diabetic and nondiabetic patients undergoing percutaneous coronary intervention in routine clinical practice. We therefore studied the long-term effectiveness and safety of sirolimus versus paclitaxel stents overall and stratified by the absence or presence of diabetes. Methods and Results— We compared sirolimus and paclitaxel stents in a propensity-score matched cohort of 2054 pairs of patients (835 matched pairs of diabetic patients and 1219 matched pairs of nondiabetic patients) undergoing percutaneous coronary intervention in Ontario between December 1, 2003 and March 31, 2006. The cohort was derived from the Cardiac Care Network of Ontario percutaneous coronary intervention registry and linked to population-based administrative health databases. In the overall cohort, there was no difference in rates of target-vessel revascularization ( P =0.47), myocardial infarction ( P =0.71), or death ( P =0.49). As compared with paclitaxel stents, the use of sirolimus stents was associated with a significantly lower 3-year rate of target-vessel revascularization in nondiabetic patients (8.3% versus 10.0%, P =0.01), but not in diabetic patients (12.7% versus 10.3%, P =0.07). Rates of all-cause mortality were similar in patients receiving sirolimus stents versus paclitaxel stents in both the diabetic (8.4% versus 9.2%, P =0.91) and nondiabetic (4.6% versus 3.0%, P =0.22) groups. Conclusions— In this large observational study, patients receiving paclitaxel and sirolimus stents had similar mortality rates, but nondiabetic patients receiving sirolimus stents were significantly less likely to require repeat revascularization.
Development of colony phenotype in social insects controlled by frequency-dependent thresholds among workers

Field: Agricultural and Biological Sciences (Life Sciences)

The frequency of workers adopting different behaviours often depends on thresholds. If too few workers are foraging, for example, then those workers with relatively low foraging thresholds begin to collect food. The regulation of colony phenotype is controlled by frequency-dependent feedback among worker threshold values. I show that, for a given average threshold value among workers, variability in thresholds influences the frequency of workers that adopt a particular behaviour. This conclusion applies whenever the tendency of a developmental unit to adopt a particular phenotype depends on the frequency of other units with that phenotype. Social insects are unusual, however, because the distribution of thresholds among developmental units (workers) depends on the number of times the queen has mated.
Uterine torsion in second trimester of pregnancy followed by a successful-term pregnancy

Field: Medicine (Health Sciences)

Uterine torsion is defined as rotation of the uterus of more than 45° on its long axis. It is an unusual complication of pregnancy and for most obstetricians it probably represents a ‘once-in-a-lifetime’ diagnosis. Fetal mortality up to 12% and occasional maternal mortality are reported. A 22-year-old second gravida presented at 22+ weeks gestation with severe abdominal pain and shock. Laparotomy was done for suspected abruptio placenta, when torsion of the uterus to 180° was diagnosed. Posterior hysterotomy was performed. She conceived the next year and was delivered at term by caesarean section. Uterine torsion is a rare complication of pregnancy and obstetricians should have this complication in mind when performing a caesarean section for undiagnosed severe abdominal pain in pregnancy. Anatomical landmarks should be defined if possible, prior to uterine incision during a caesarean section, to avoid posterior hysterotomy
RELATION OF DIETARY THIAMINE AND PANTOTHENIC ACID CONCENTRATIONS TO THEIR TISSUE LEVELS

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Relation of Dietary Thiamine and Pantothenic Acid Concentrations to Their Tissue Levels Get access Nutrition Reviews, Volume 5, Issue 2, February 1947, Pages 41–42, https://doi.org/10.1111/j.1753-4887.1947.tb04104.x Published: 01 February 1947
Figure S3 from The Oncolytic Adenovirus XVir-N-31 Joins Forces with CDK4/6 Inhibition Augmenting Innate and Adaptive Antitumor Immunity in Ewing Sarcoma

Field: Medicine (Health Sciences)

<p>Supplemental Figure 3: Characterization of tumor-infiltrating T cells at the end of experiment (A673 xenografts).</p>
Cumulative Response to Various Recurrent Selection Schemes in Soybean: Oil Quality and Correlated Agronomic Traits1

Field: Agricultural and Biological Sciences (Life Sciences)

practiced in a soybean [ Glycine max (L.) Merr.] population to indirectly decrease linolenic acid percentage in the seed oil. Three selection schemes were employed during specific stages of the program: Individual or mass (Cycles 1 to 3), mass plus within half‐sib family (Cycles 4 to 7), and S 1 ‐progeny selection (Cycle 8). In addition, reverse selection for low oleic acid (LO) was initiated in Cycle 6 and continued simultaneously with HO selection. Objectives of this study were to evaluate cumulative selection response for fatty acid traits and other correlated traits, and to evaluate the potential for further selection progress. To achieve those objectives, selected lines from each cycle were composited in bulk populations and tested in eight environments. Regression analysis showed that the average rate of change in oleic acid percentage increased from 1.15 f 0.17% per cycle (HO mass selection) to 2.64 ± 0.24% per cycle (HO mass plus within half‐sib family selection). The difference in observed genetic gains was consistent with theoretical expectation. Rate of change in linolenic acid percentage, however, did not increase in magnitude, averaging −0.34 ± 0.03% (HO mass selection) and −0.24 ± 0.05% per cycle (HO mass plus within half‐sib family selection). Divergent responses to HO and LO selection for oleic and linolenic acid percentages indicated that genes governing those traits were not fixed after six cycles. Seed weight and days to maturity were correlated with selection for oleic acid, but no consistent trends throughout the selection program were noted for seed yield or oil and protein percentages. Although further progress from HO selection can be expected, a change in selection criterion to low linolenic acid percentage may be justified to minimize bias caused by genotype ✕ environment interaction.
The TMA-93: A New Memory Test for Alzheimer’s Disease in Illiterate and Less Educated People

Field: Medicine (Health Sciences)

The present study aimed at validating the Memory Associative Test of the district of Seine-Saint-Denis (TMA)-93, a new test of episodic memory. The TMA-93 was proposed to mostly less educated and multicultural elderly population composed of 376 healthy controls (HC) and 94 patients with Alzheimer’s disease (AD). The construct validity was checked by studying correlations with a widely used memory test (the Free and Cued Selective Reminding Test [FCSRT]) in the subsample of literate patients. Results showed that (i) all the TMA-93 scores of the patients with AD were lower than those of the HC, (ii) the TMA-93 total score identified patients with AD with a high sensitivity (88%) and very high specificity (97%), and (iii) the TMA-93 total score was strongly correlated with both free recall and total recall scores of the FCSRT. Taken together, results showed that the TMA-93 is a reliable tool to assess episodic memory in a multicultural, less educated, or illiterate population, with good construct validity for AD diagnostic accuracy.
The effects of cyber harassment and its relationship with coping styles, coping self-efficacy and the actions victims take

Field: Psychology (Social Sciences)

This study examined cyber harassment in a Singapore population. Victims of cyber harassment were asked about aspects of their harassment incident. Cyber harassment was also studied in relation to anxiety, coping styles, coping self-efficacy as well as the actions that victims had taken against their harassers. The study included a college age sample as well as public respondents and responses were collected through an online survey. Results revealed 42% of the victims had been harassed by strangers, 72% of the incidents had lasted for less than a month, 42% of victims were harassed on social networking sites, 36% of victims had first encountered their harassers offline and 72% of these harassment incidents were purely online encounters. Results also suggested that a problem-focused coping style, high coping self-efficacy and taking direct actions against the harasser could contribute to lower anxiety levels. On the other hand, an emotion-focused and maladaptive coping style contributed to higher levels of anxiety. Coping self-efficacy was positively correlated with a perceived satisfactory resolution of the harassment incident. While some of these results were non-significant, all correlations were in the hypothesized direction. The results and implications of the study are discussed in relation to the actions and coping styles that victims can take to protect themselves from future psychological impacts.
Report of the Surgeon - General of the Army for the Fiscal Year Ending June 30, 1889.

Field: Medicine (Health Sciences)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Yosemite Watershed Restoration Project

Field: Environmental Science (Physical Sciences)

Abstract NOTE: The first page of text has been automatically extracted and included below in lieu of an abstract Session 2651 Yosemite Watershed Restoration Project Eliot S. Metzger, Sonya M. Havens, Vivian Chang, Kathryn M. Clifton, and John M. Lendvay University of San Francisco, San Francisco, CA Abstract: The Bay View-Hunters Point neighborhood of San Francisco has a history of significant environmental degradation and a population comprised mainly of underrepresented minorities. This highly industrialized area lies adjacent to Yosemite Slough, on the western shore of South San Francisco Bay. Under normal conditions local runoff is diverted into the city’s combined sewer system. However, during heavy precipitation events the runoff is discharged with untreated sewage directly to the slough through the combined sewer overflow system. Moreover, Yosemite Slough is bordered by the San Francisco 49er’s stadium parking lot, heavy industry, and the former Hunters Point Naval Shipyard, each of which provide a source of diffuse urban and industrial pollution through direct runoff and groundwater – surface water interactions. The Yosemite Watershed Restoration Project is a community-based assessment of water quality at Yosemite Slough and is organized and led by undergraduate research assistants at the University of San Francisco. Teams of local high school students are trained on environmental concerns impacting the community and on sampling protocols necessary to conduct a detailed water quality assessment of the slough. The students examine the impact of sewage treatment plant outflow, good urban water quality practices, and sources of impervious surface runoff. Additionally, the students take part in enrichment programs and a local wildlife census. Data from this water quality assessment and wildlife census will be incorporated into a community- wide effort to influence redevelopment decisions to minimize environmental impacts. Through the community-involved environmental assessment, this project will lay a foundation for community empowerment so that decisions regarding future redevelopment projects will be scientifically sound and informed. Background: Yosemite Slough (Yosemite Watershed) in the Bay View-Hunters Point (BVHP) community is located in the southeast corner of the City and County of San Francisco, California. Bay View- Hunters Point is a low-income community largely comprised of people of color. Cumulative air, land, and water pollution disproportionately affect the community; it has some of the highest rates of breast and cervical cancer, asthma, and respiratory illnesses in California. Over 100 brown-field sites, two large power plants, a heavily contaminated naval base, and the city’s sewage treatment facility are contained within this five square mile community. “Proceedings of the 2003 American Society for Engineering Education Annual Conference & Exposition Copyright © 2003, American Society for Engineering Education”
A Study of the Shapes of Economic Phenomena for the Purpose of Elaborating More Rational Techniques for the Opening up of Tayga Territories

Field: Economics, Econometrics and Finance (Social Sciences)

Starting from the premise that “shape is an important [spatial] property” (Bunge), the author analyzes the optimal shapes and dimensions of fragmented plots of arable land typical of Yakutia and other parts of the forest zone of the USSR. The optimal shape of an arable plot in a forest clearing is found to be an elongated piece of land of about 200–250 meters by 750–1500 meters and an area of 15 to 30 hectares. A program of land consolidation in the last decade has aimed at the elimination of excessively small plots and the expansion of mean plot size within the limitations of the Yakutian environment, where the presence of ground ice and thermokarst conditions produces a complex system of thaw depressions impeding the development of agriculture.
Government Mobile Apps: Analysing Citizen Feedback via App Reviews

Field: Computer Science (Physical Sciences)

Governments worldwide are increasingly embracing digital transformation initiatives to enhance service delivery, engage citizens, and achieve better outcomes. However, obtaining continuous feedback on these initiatives poses a substantial challenge. This paper investigates the feasibility of leveraging mobile app reviews as a valuable source of citizen feedback on government digital services. We analyse 100,146 app reviews from 129 government mobile apps in Australia and identify several functional and usability issues. These include issues such as app instability, complexity, integration problems, navigation difficulties, inaccuracies, and challenges with ID verification and authentication processes. Furthermore, we uncover several factors that influence user satisfaction, including accuracy and reliability, convenience, dependability, user-centric design, and overall user-friendliness. These findings demonstrate a strong correlation between user feedback and the government's digital transformation strategy, underscoring the viability of mobile app reviews as a cost-effective avenue for collecting citizen feedback.
Effects of KAI gene expression on ferroptosis in pancreatic cancer cells

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The specific role and mechanism of ferroptosis in the development of pancreatic cancer (PC) remain to be elucidated. The present study aimed to investigate the effects of the overexpression of the KAI1 gene on the ferroptosis of the human PC cell line MIA PaCa‑2. MIA PaCa‑2 cells infected with pCMV‑KAI1 and selected by G418 and KAI1 protein were analyzed by western blotting. The MIA PaCa‑2 cells with a stable expression of the KAI1 gene were termed MIA PaCa‑2‑KAI1. The proliferative capacities of MIA PaCa‑2 and MIA PaCa‑2‑KAI1 cells were detected using Cell Counting Kit‑8. The reactive oxygen species (ROS) in the cells were compared by flow cytometry. The expressions of ferroportin (FPN) and glutathione peroxidase 4 (GPX4) protein were analyzed by western blotting. The KAI1 stable expression cell line was confirmed and relabeled as MIA PaCa‑2‑KAI1. No significant differences in the proliferation of MIA PaCa‑2 and MIA PaCa‑2‑KAI1 were identified. Following treatment with a ferroptosis blocker, the increase in the proliferation of MIA PaCa‑2‑KAI1 (from 2.06±0.02 to 2.75±0.02) was more evident compared with MIA PaCa‑2 (from 2.94±0.02 to 2.95±0.02; P<0.05). The ROS in MIA PaCa‑2‑KAI1 was significantly higher compared with MIA PaCa‑2 (P<0.05). FPN and GPX4 protein demonstrated higher expression levels in MIA PaCa‑2‑KAI1 compared with MIA PaCa‑2. Moreover, KAI1 exerted an obvious promotion effect on FPN expression. This study identified that the high expression of the KAI1 gene promoted the occurrence of ferroptosis in PC cells through its extensive effect on FPN and GPX4. KAI1‑induced ferroptosis did not significantly inhibit the proliferation of PC cells.
Managing Collaboration: Adding Communication and Documentation Environment to a Product Development Cycle

Field: Business, Management and Accounting (Social Sciences)

This chapter describes a repeatable process for managing communication and interaction patterns of multidisciplinary teams during the product development life cycle. Collaboration among discipline specialists is particularly important in the early phases of the product development cycle, and systemic communication throughout the cycle is critical, especially if the discipline specialists change during the cycle. To maintain an organized project and the documentation associated with it, project management needed systemic communication. Communication is an important attribute, not mentioned but assumed within the RUP process. "Communication leads to community, that is to understanding, intimacy and mutual valuing". To create this community of better understanding, intimacy, and mutual valuing, we developed a Communication and Document Environment (CDE), which was added to the product life-cycle plan. Universities, government organizations, and businesses need a more robust communication environment to accommodate a high turnover rate of multidisciplinary experts.
Detection of Expression of Immunity Related Cytokines in NDV Infected CEF

Field: Immunology and Microbiology (Life Sciences)

In this study,we used Newcastle disease virus (NDV)strains F48E9 and La Sota infected chicken embryo fibroblast (CEF) with 10-day-age chick embryo 24 hours after the infection,we isolated the total RNA from the CEF and detected the expression quantities of 21 sorts of immunity related cytokines by RT-PCR,and then scanned of the corresponding bands. The results showed that,wether or not the CEF were infected with the NDVs,we could not detect the corresponding bands of IL-2,IL-3,IL-4,IL-21. By analysis of stastistics,we found that IFN-β,IFN-γ,IL-9,IL-12-P35,IL-12-P40 showed statistically significant difference among interblocks,but only IFN-γ and IL-9 presented the statistically significant difference between F48E9 infected CEF and La Sota infected CEF.
Nettle (Urtica Dioica L.) Modulates Angiogenesis by Targeting the PI3K/AKT/eNOS Pathway in Prostate Cancer

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Background: Medicinal plants, predominantly those rich in polyphenolic mixtures, have been recommended to have chemopreventive and chemotherapeutic effects. This study aimed to investigate the effects of Urtica dioica L. extract (UDE) on angiogenesis and prostate cancer (PCa) cell progression through the phosphoinositide 3-kinase/Protein kinase B/ endothelial nitric oxide synthase (PI3K/AKT/eNOS) signaling pathway.Method: This study employed an in vitro experimental design using PCa cell lines. To gain mechanistic insights into the anti-proliferative properties of UDE, PCa cell proliferation was assessed using an MTT (3-(4, 5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide) assay in DU-145 cells (incubated for 48h). Also, we explored expression patterns of PI3K/AKT/eNOS pathway genes with therapeutic potential (with 50 µg/ml of UDE) in DU-145 cells by quantitative polymerase chain reaction and western blotting assay. Furthermore, we applied the ELISA cell death assay kit to reveal the apoptotic effects of UDE on PCa cells. Statistical analysis was determined using the Mann-Whitney U test and P ≤ 0.05 was considered statistically significant. Results: UDE significantly decreased the cell viability after 48 h of treatment in DU-145 cells. Also, reducing the vascular endothelial growth factor (VEGF) levels revealed anti-angiogenic outcomes. Also, the eNOS level in the PI3K/AKT/eNOS pathway is dramatically alleviated upon treatment with UDE. Moreover, the apoptosis rate of DU-145 cells was enhanced compared with the control group.Conclusion: The antitumoral activity of UDE was prominent in its persuasive anti-angiogenic potential, as UDE contributed to a striking diminish in PI3K/AKT/eNOS pathway in PCa and diminished the VEGF expression.
Study on chemical compounds of Radix Glehniae

Field: Chemistry (Physical Sciences)

目的 深入研究中药北沙参(Glehinia littoralis F. Schm idt ex M iq.)的化学成分.方法 采用溶剂法对北沙参化学成分进行粗分,运用硅胶柱色谱进行分离纯化,通过波谱分析鉴定结构.结果 从北沙参中分离得到了8个化合物,分别鉴定为花生酸(1),亚油酸(2),人参醇(3),福尔卡烯炔二醇(4),十八碳二烯酸单甘油酯(5),阿魏酸(6),胡萝卜苷(7),齐墩果酸(8),结论化合物1,2,5,8为首次从北沙参中分离得到。
The Power of English

Field: Social Sciences (Social Sciences)

Spanish was entrenched as the language of public-school instruction with the advent of elected governors in the middle of the previous century. Since then heated exchanges over the language-education nexus subsided significantly. English is still associated with upward socio-economic mobility and facilitated migration to the US mainland. This chapter also explores the linguistic panorama and linguistic enclaves on the island. The largest pockets of English speakers are in the San Juan metropolitan area and areas adjacent to military installations. Data also reveal that since Puerto Rico’s economic downturn in the first decade of this century the percentage of English speakers on the island has dropped significantly. The drop coincides with a mass migration off the island. Consequently, English is no longer associated exclusively with Americans. It is increasingly becoming a critical medium for communication with stateside Puerto Ricans.
On Jorge Becoming a Boy: A Counselor's Perspective

Field: Psychology (Social Sciences)

In this portrait, Travis Wright, writing as a psychology counselor in training, brings the reader into one morning's events in his clinical work with Jorge, a three-year-old boy whose family is experiencing difficult times. Throughout the morning at Jorge's day-care center, Wright encounters scenarios that force him to ask questions about child development, gender identity, masculinity, and family dynamics. Wright observes that boys are often thrust into a gendered world dictated by adult norms before they can make sense of their own life events and losses. The portrait is a poignant narrative of Jorge's experiences in and out of his day-care center, as well as a moving self-reflection on Wright's own gender identity.