jimnoneill/paper-to-field-training huggingface dataset:
WATER PLANT Azolla sp. AS FEED ADDITIVE AND THE EFFECT ON PRODUCTION PERFOMANCE OF BROILER HUBBARD STRAIN

Field: Agricultural and Biological Sciences (Life Sciences)

Penelitian ini dilakukan untuk memanfaatkan suatu tanaman air Azolla sp. yang memiliki mikrosimbion mikroalga (ganggang) Anabaena azollae., yang dikembangkan sebagai formula imbuhan pakan (feed additive) pada pakan ayam pedaging (broiler). Formula imbuhan pakan ini adalah untuk pakan komplit ayam pedaging, baik fase starter maupun finisher. Hasil penelitian menunjukkan bahwa pemberian imbuhan pakan Azolla sp. yang bersimbiosis dengan A. azollae pada pakan jadi merk Malindo yang diujikan untuk ayam pedaging strain Hubbard, baik fase awal (starter) dan kemudian fase akhir (finisher) memberikan performa Pertambahan Bobot Badan Harian (PBBH) ayam broiler strain Hubbard sebesar 52,42 gram/ekor. Sedangkan pencapaian bobot badan akhir rata-rata sebesar 1,880.95 gram/ekor. Baik pertambahan bobot badan harian maupun pencapaian bobot badan akhir secara umum masih dalam kisaran sebagaimana disarankan, demikian pula konsumsi pakannya. Tetapi, kandungan kolestrol daging broiler perlakuan menunjukkan penurunan hingga perlakuan level 2 %. Berdasarkan hasil penelitian maka dapat disimpulkan bahwa Azolla sp. yang bersimbiosis dengan mikroalga A. Azollae dapat digunakan sebagai imbuhan pakan pada pakan komplit ayam pedaging dengan tidak memberikan efek terhadap penurunan palatabilitas maupun metabolisme, dan juga sumber bahan pakan ini merupakan non konvensional, sehingga hal ini merupakan potensi yang dapat dikembangkan untuk masa mendatangkan dengan meningkatkan efisiensi pakan dan kemampuan produksi ayam broiler.
Bidirectional power sharing in an ac/dc system with a dual active bridge converter

Field: Engineering (Physical Sciences)

This study introduces a bidirectional power sharing scheme between an ac electric utility and a dc microgrid. These two are connected together through an interlinking converter (IC) and a dual active bridge (DAB). The proposed control scheme allows predefined amount of power to be supplied from the ac to dc side or the other way around. The DAB is connected at the dc side of the IC and it controls the bidirectional power flow. The dc microgrid contains dc–dc converters, where boost converters are used with the sources and buck converters are used to supply loads. These dc–dc converters and the DAB are controlled by state feedback with integral control in a linearised discrete domain. The DAB linearisation and control law are presented in detail. The dc microgrid is controlled by conventional V‐P droop where the power from/to the ac side is considered as negative/positive load. Detailed simulation results are presented to validate the proposal. Also some hardware results are included that support the findings.
Effect of different milking methods on milk yield and growth of lambs

Field: Agricultural and Biological Sciences (Life Sciences)

Indian sheep are unexploited for their milk production potential. Among 43 sheep breeds, Patanwadi is considered to have higher milk yield. With the aim to compare different milking methods to get more yield and better lamb growth, 18 Patanwadi ewes having single born lambs were selected along with their lambs and randomly divided into three groups. Milk yield potential of ewes in Gr A was measured by hand milking method, whereas of Gr B by weigh-suckle-weigh method and of Gr C by hand milking followed by weigh-suckle-weigh method. Average daily milk yield was significantly (P<0.05) higher (658.00±24.60 ml) in Gr C compared to the ewes in Gr A (541.89±20.00 ml). Gr A lambs were fed by bottle feeding method while, Gr B and C lambs by suckling their dams. The lambs in suckling groups (Gr B and C) had significantly (P<0.05) higher growth compared to group A. The pre-weaning average daily gain (ADG) for Gr A lambs was 119 g as compared to Gr B and C (156 g). It was inferred that post-milking suckling method is the better method in Patanwadi ewes with respect to milk yield as well as for higher body weight gain in lambs.
Hypothyroidism and depression. Evidence from complete thyroid function evaluation

Field: Medicine (Health Sciences)

To evaluate the relationship between hypothyroidism and depression, thyroid function was evaluated in 250 consecutive patients referred to a psychiatric hospital for treatment of depression or anergia. Twenty of the 250 patients had some degree of hypothyroidism. Two patients (less than 1%) were identified with grade 1 (overt); nine patients (3.6%), grade 2 (mild); and ten patients (4%), grade 3 (subclinical) hypothyroidism. These results suggest that a significant proportion of patients with depression and anergia may have early hypothyroidism, the cases of about half of which are detected only by thyrotropin-releasing hormone (TRH) testing. Because hypothyroidism can produce signs and symptoms of depression and can coexist as a second illness in depressed patients, patients with early hypothyroidism may be candidates for thyroid replacement therapy. Clinical examination and measurement of triiodothyronine resin uptake thyroxine and baseline thyroid-stimulating hormone (TSH) levels, and TSH response to TRH are necessary to identify candidates for thyroid replacement among cases diagnosed by descriptive criteria as having either major or minor depression, particularly those that are atypical or treatment resistant.
Computational Model Predicts Patient Outcomes in Luminal B Breast Cancer Treated with Endocrine Therapy and CDK4/6 Inhibition

Field: Medicine (Health Sciences)

Abstract Purpose: Development of a computational biomarker to predict, prior to treatment, the response to CDK4/6 inhibition (CDK4/6i) in combination with endocrine therapy in patients with breast cancer. Experimental Design: A mechanistic mathematical model that accounts for protein signaling and drug mechanisms of action was developed and trained on extensive, publicly available data from breast cancer cell lines. The model was built to provide a patient-specific response score based on the expression of six genes (CCND1, CCNE1, ESR1, RB1, MYC, and CDKN1A). The model was validated in five independent cohorts of 148 patients in total with early-stage or advanced breast cancer treated with endocrine therapy and CDK4/6i. Response was measured either by evaluating Ki67 levels and PAM50 risk of relapse (ROR) after neoadjuvant treatment or by evaluating progression-free survival (PFS). Results: The model showed significant association with patient’s outcomes in all five cohorts. The model predicted high Ki67 [area under the curve; AUC (95% confidence interval, CI) of 0.80 (0.64–0.92), 0.81 (0.60–1.00) and 0.80 (0.65–0.93)] and high PAM50 ROR [AUC of 0.78 (0.64–0.89)]. This observation was not obtained in patients treated with chemotherapy. In the other cohorts, patient stratification based on the model prediction was significantly associated with PFS [hazard ratio (HR) = 2.92 (95% CI, 1.08–7.86), P = 0.034 and HR = 2.16 (1.02 4.55), P = 0.043]. Conclusions: A mathematical modeling approach accurately predicts patient outcome following CDK4/6i plus endocrine therapy that marks a step toward more personalized treatments in patients with Luminal B breast cancer.
Mechanism of RORα in Promoting Osteoarthritis through p53 Deubiquitination-Mediated Chondrocyte Ferroptosis

Field: Medicine (Health Sciences)

While ferroptosis is increasingly implicated in the pathogenesis of osteoarthritis (OA), a comprehensive transcriptomic profile of this process in human chondrocytes is lacking. We compared the gene expression profiles of primary chondrocytes isolated from normal and OA human cartilage using RNA-seq to identify key regulatory genes and pathways. Subsequently, we performed Gene Ontology (GO) enrichment analysis to characterize the functional significance of differentially expressed genes. The majority of variation was found between OA and normal chondrocytes, revealing a distinct ferroptosis-related gene signature in the diseased state. Specifically, key ferroptosis suppressors, including SLC7A11 and GPX4, were downregulated, while promoters such as ACSL4 and FTH1 were upregulated in OA chondrocytes. Functional clustering based on GO terms highlighted the disruption of iron homeostasis and dysregulation of glutathione metabolism as critical pathways in OA progression. Our findings provide a transcriptomic basis for the pathogenic role of ferroptosis in OA, corroborating in vitro and in vivo functional experiments, and this dataset serves as a resource for investigating novel therapeutic targets.
Self-unlinked simple closed curves

Field: Mathematics (Physical Sciences)

interiors of a collection of disjoint 3-cells each of diameter less than S. A set X is locally tame at p if p has a closed neighborhood in X which is a tame complex in M. If X is not locally tame at p then p is a wild point of X. A set is called nicely wild if the union of its wild points is a tame 0-dimensional set. For J an arc or scc we make the following definitions, the first of which is used in [1]. The penetration index P(J,x) of J at a point x E J is the smallest cardinal number n such that there are arbitrarily small 2-spheres enclosing x and containing no more than n points of J. The penetration index P(J) of J is the least upper bound of the cardinal numbers P(J, x), for all x E J. If J is nicely wild, then the nice penetration index NP(J) of J is the smallest integer n such that, for every E > 0, the set of wild points of J can be covered by the interiors of a collection of disjoint 3-cells each with diameter less than s and such that the boundary of each 3-cell intersects J in no more than n points. (The union of members of this collection is called a taming s-set of J of index n.) CONJECTURE. There is a nicely wild scc J such that NP(J) # P(J).
Quantitative and Qualitative Evaluation of the Lift-assist Device during Jackhammering Task

Field: Health Professions (Health Sciences)

Background: Jackhammers are commonly used on construction sites, and their general use comes with several injury risks, especially focused on lifting the jackhammer. A Lift-assist (LA) device is available that is aimed at eliminating the risk to the user from lifting. However, to date no scientific study has been conducted to determine if the LA provides any benefits to the user. The goal of this study was to make quantitative comparisons and qualitative assessments of operating a jackhammer with and without a LA.
Methods and findings: Eight experienced jackhammer operators broke a 0.9 × 0.9 m section of concrete with two different weights of jackhammers with and without a lift-assist. Muscle activity of the upper body was reduced (approx. 40%) during the lifting portion of the task when using the LA. The reduction of the muscle activity required to lift the jackhammer also enabled the subjects to retain a better posture throughout the lift. Additionally, grip pressure was reduced in the lifting portion of the task. While the LA reduced the time required to lift the jackhammer, no change in overall task completion time was observed due to large variations in the time effect of the lift-assist among subjects and the relatively minor contribution of lifting time to the total task time. A longer study that allowed subjects to better adapt to the LA might be required to assess potential effects on task efficiency. Overall the subjects perceived the LA to provide a benefit to the user during the jackhammer task, and reduced the physiological stress experienced by the operator during the lifting portion of the task.
Conclusions: These results indicate that use of the LA can potentially translate to a reduction in lifting related injury risks to the operator.
Wormhole Detection using Zonal Security Nodes in Wireless Sensor Networks

Field: Computer Science (Physical Sciences)

Wireless sensor networks, or WSNs, are selfconfigured, spatially distributed, large-scale networks composed of small-sized devices called sensors. These networks are deployed primarily in hostile or remote environments where monitoring is required either for critical observation or security purposes. These networks hold a wide range of applications in sectors including medical, military, environmental, industrial, infrastructural, and many more. Data security is one of the primary concerns in these networks, as they use the common medium of air for transmission. Wormhole attacks have been a constant challenge to WSN and disrupt routing in the network. We present an overview of WSN and propose an algorithm based on packet leashing and ZRP that employs specialized nodes to detect and alert the presence of a wormhole in the network.
A Randomized Clinical Trial to Evaluate the Effect of Programmed Labour and Epidural Analgesia on Onset and Duration of Stages of Labour

Field: Medicine (Health Sciences)

Background: The present study was conducted to evaluate the effect of programmed labour and epidural analgesia on onset and duration of stages of labour. Materials and Methods: This randomized interventional clinical trial was conducted in department of Anaesthesia at Kamla Nehru State Hospital for Mother and Child, Indira Gandhi medical College Shimla in collaboration with Department of Anaesthesia on eighty uncomplicated pregnant women that were divided into two groups of 40 patients each by block randomization. One group received programmed labour protocol (Injection Pentazocine 6 mg + Injection Diazepam 2 mg IV + Injection Tramadol 1-1.5 mg/kg I.M the rafter a single dose of injection Drotaverine 40 mg intravenously) while the other group received epidural analgesia. They were monitored for VAS score before and after intervention. Results: The two groups were comparable in terms of patient’s characteristics (age, parity, period of gestation). Both groups were comparable in terms of onset of labour Spontaneous labour seen in 65-70% of subjects. Regarding the duration of active phase of labour, in our study, in group 1 duration of active phase of 1 stage of labour was 215 min and in group 2 it was 204 minutes with standard deviation of 32 minutes in group 1 and 40.4 minutes in group 2 respectively. Using student ‘t’ test this difference was found to be significant statistically (p value <0.005). The mean duration of second stage of labour was 24.3 in group 1 and 35.8 min in group 2 with significant p value<0.005. The mean duration of third stage of labour in our study was 5.89 minutes in group 1 and 5.7 min group 2. This difference is statistically insignificant (using student ‘t’ test (>0.005). Conclusion: Our study concluded that there was significant difference in first and second stage of labour in both groups while there was no significant difference in third stage and onset of labour in both groups.
Simulation of ISAR image of complex targets based on GRECO

Field: Computer Science (Physical Sciences)

In this paper,an ISAR imaging simulation method combined with graphical electromagnetic computing(GRECO) technique is introduced.The electromagnetic scattering data of maneuvering targets is obtained by using of GRECO.The radar echo of maneuvering targets is got by transmitting linear FM signal and an ISAR imaging of simulated echo is carried out.Different from point target simulation,3D target simulation and imaging is very similar to the reality and is more suitable for application and imaging effects analysis and study of algorithm improvement and anti-interference.The scattering field of target surface is analyzed based on high frequency predict theory and is calculated based on the physical optics(PO) method and physical theory of diffraction(PTD).The ISAR images can be obtained with different motion compensation methods and reconstruction algorithms.The simulation results of complex target show that the method has the characteristics of correctness,effectiveness,and real-time performance.
The effects of duration of sprinkling and temperature of the drinking water on the feed intake and growth of pigs at high ambient temperature

Field: Agricultural and Biological Sciences (Life Sciences)

Morrison et al. (1972), Hsia, Fuller & Koh (1974), and Ho & Khoo (1977) showed that sprinkling can alleviate the adverse effects (Straub et al. 1976) of high ambient temperature on feed intake and growth of pigs. Vajrabukka, Thwaites & Farrell (1986) demonstrated that pigs need to be thoroughly wet by sprinkling at least once every 60 min if high evaporative rates are to be maintained, but little is known of the relative benefits of different sprinkling regimes for pigs growing at high temperatures.
Optimizing the Prevention of SARS-CoV-2 Transmission Through the Covid-19 Response Mosque

Field: Health Professions (Health Sciences)

This service aims to participate in the success of the efforts made by the management of the Al-Muttaqin prayer room in implementing health protocols according to government regulations regarding guidelines for organizing activities in houses of worship. It is also to educate the public or congregation about the meaning of Covid-19 and health protocols. This is because some people doubt that the Covid-19 virus can spread to farming communities. Because, for some of them, farmers only work in the fields. The methods used in the implementation of this service are: procurement of cleaning equipment, making liquid soap, spraying disinfectants, cleaning the prayer room, pasting posters, and distributing soap from house to house as well as an invitation to obey health protocols. The result achieved: the community or congregation became aware of the health protocol, which they then realized in the form of keeping the distance between congregations and bringing personal prayer mats from home. The prayer room management is also assisted by the procurement of cleaning equipment and additional personnel in the success of government regulations in the prayer room environment so that the implementation of health protocols is realized.
The spectroscopic signature of the Co magnetic state in CoxNbSe2superconducting single crystals

Field: Physics and Astronomy (Physical Sciences)

The magnetic state of Co in NbSe2 has been studied with low temperature scanning tunneling microscopy and spectroscopy. The local density of states (DOS) at the surface of CoxNbSe2, for different dopings x, does not show bound states predicted in the case of superconductors with magnetic impurities. Only occasionally local asymmetries in the DOS are found at some impurity sites and they appear to be very local. These asymmetries, together with a very low magnetic moment obtained from susceptibility measurements, point towards a possible Kondo effect at play. Tunneling spectra recorded at the impurity site in the presence of a magnetic field of 7 T (i.e. when the sample is in the normal state) show a dip-like feature at the Fermi energy, reminiscent of the Fano resonance observed in magnetic adatoms on metallic surfaces.
Application of serum lipase in acute or chronic kidney insufficiency

Field: Medicine (Health Sciences)

Objective To explore the serum enzyme in order to reflect the chances of the serum enzymology in kidney insufficiency.Methods The specimen was monitored by routine methods,the quality was controlled by definitive number and the serum lipase was assessed by normative rate nephelometric procedure.Results The serum lipase of the acute or chronic kidney insufficiency (especially in the urenia) was significantly increased than that of normal control group,glomerulonephritis group,nephrotic syndrome group(P0.01).The other four groups had no significant difference compared with each other(P0.05).Conclusion The serum lipase is the effective index of the diagnosis on the acute or chronic kidney insufficiency.
Late dental effects of chemotherapy and radiotherapy in childhood cancer survivor: case report

Field: Dentistry (Health Sciences)

Chemotherapy drugs and radiotherapy in the head and neck region are considered possible to interfere with odontogenesis. Patients may present alterations such as tooth agenesis, shortening or root malformation, enamel hypoplasia and microdontia. Such effects do not occur in adults, as they already have the dental structures formed. The objective of this study is to describe, through a case report, the dental alterations and implications for the clinical practice of a patient who received chemotherapy and radiotherapy in childhood. A 12- year-old female patient was diagnosed with embryonal rhabdomyosarcoma in the right parotid gland region at 5 years of age. Antineoplastic treatment consisted of IRS IV chemotherapy protocol: ifosfamide (IFO) - doxorubicin (DOXO) - etoposide (VP16) followed by vincristine - dactinomycin - cyclophosphamide (VAC) / vincristine - ifosfamide - etoposide (VIE) alternated, in addition to conventional radiotherapy, with a total dose of 45 Gy. The patient developed important dental alterations, such as root malformation in most teeth, microdontia and enamel hypoplasia, being essential the role of the dentist. Currently, after 6 years of anticancer treatment, she has regular dental follow-up.
The Effect of Radium on Blood Flow in the Human Uterine Cervix Measured by Local Hydrogen Clearance

Field: Medicine (Health Sciences)

Abstract. Cervical blood flow was measured by the local hydrogen gas clearance method in 15 patients with untreated carcinoma of the uterine cervix and in 16 patients six to eight weeks after radium irradiation. Mean cervical blood flow was 75.5 ml/min. 100 g in the untreated group and 92.4 ml/min. 100 g in the treated group.
A case of angioedema with dysarthria mimicking transient ischemic attack

Field: Medicine (Health Sciences)

An 85-year-old woman was transported to our emergency room by ambulance with a complaint of slurred speech. Neurological examination revealed dysarthria only. We considered that lingual edema identified on physical examination might have influenced dysarthria. However, we were unable to perform sufficient evaluation, since she could not open her mouth widely or push the tongue out beyond the lips. We considered the incidence of acute cerebrovascular disease because of the acute onset, and performed emergency brain MRI. Imaging revealed that although no abnormality was present in the brain parenchyma, edema of the tongue and soft palate was evident on T2-weighted sagittal imaging. We confirmed the dysarthria was caused by tongue edema due to angioedema. In addition, we diagnosed angiotensin-converting enzyme inhibitor (ACEI)-induced angioedema, because ACEI had been started 2 months earlier as pharmacotherapy for hypertension. Tongue swelling due to angioedema should be considered when examining patients with dysarthria.