jimnoneill/paper-to-field-training huggingface dataset:
GHS101 and GHSP26 improves boll retention in upland cotton grown under high temperature of semi-arid subtropical climate

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract

Background Cotton is a natural fibre producing crop grown worldwide where agro climatic conditions match with its growth and reproduction. High temperature is a major environmental factor affecting cotton production due to climate change. Only way to cope with high temperature is to breed for the tolerance. High temperature tolerance is a complex mechanism that includes many genes by which cotton responds to stress. Genes conferring heat stress can be best studied in segregating population like F2 grown under stressed environment. Results Based on contrasting traits (boll retention percentage), two cotton cultivars i.e. FH-Lalazar (High temperature susceptible) and CRIS-9 (High temperature tolerant) were evaluated for eight heat stress related genes. Out of eight, two genes (i.e. GHS101 and GHSP26) were present only in tolerant genotype i.e. CRIS-9 and these two were selected for further analyses. After development of F2, the morphological and yield data from parental as well as F2 population was recorded under natural high temperature conditions. The data for boll retention percentage under high temperature was recorded as an indicator of high temperature tolerance. These two genes were surveyed in 129 plants of F2 population. Most of the plants, containing both genes showed up to 81% boll retention, but some exceptions were there. Most of the phenotypic traits showed skewed variation on histogram depicting metric nature of genes. Conclusion Results demonstrated that co-segregation of boll retention property along with heat tolerant genes in F2 population is important in reproductive development of cotton under high temperature conditions. Thus, it is necessary to identify, and pyramid other genes related to high temperature tolerance at reproductive stage.
Algorithm of Reducing the Non-uniformity of Images in LED Display Panel1

Field: Computer Science (Physical Sciences)

For the purposes of reducing the non-uniformity of images in LED display panel further, propose an algorithm. First, analyze the causes of the problem which images in LED display panel have shortcomings of the non-uniformity of images. Second, introduce the development course of the correction techniques which are used to reduce the nonuniformity of images. Simultaneously, point out the ground that location correction must be carried out. Third, for the example of a LED display panel which is spliced by modules, construct the algorithm model. Forth, describe the realization steps of the algorithm in accordance with this constructed model. Finally, this algorithm is implemented in a LED display panel, whose resolution is 640×480. Experimental results show that this algorithm is able to reduce the non-uniformity of images obviously.
MicroRNA-Mediated Transformation by the Kaposi's Sarcoma-Associated Herpesvirus Kaposin Locus

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

ABSTRACT The human oncogenic Kaposi's sarcoma-associated herpesvirus (KSHV) expresses a set of ∼20 viral microRNAs (miRNAs). miR-K10a stands out among these miRNAs because its entire stem-loop precursor overlaps the coding sequence for the Kaposin (Kap) A/C proteins. The ectopic expression of KapA has been reported to lead to transformation of rodent fibroblasts. However, these experiments inadvertently also introduced miR-K10a, which raises the question whether the transforming activity of the locus could in fact be due to miR-K10a expression. To answer this question, we have uncoupled miR-K10a and KapA expression. Our experiments revealed that miR-K10a alone transformed cells with an efficiency similar to that when it was coexpressed with KapA. Maintenance of the transformed phenotype was conditional upon continued miR-K10a but not KapA protein expression, consistent with its dependence on miRNA-mediated changes in gene expression. Importantly, miR-K10a taps into an evolutionarily conserved network of miR-142-3p targets, several of which are expressed in 3T3 cells and are also known inhibitors of cellular transformation. In summary, our studies of miR-K10a serve as an example of an unsuspected function of an mRNA whose precursor is embedded within a coding transcript. In addition, our identification of conserved miR-K10a targets that limit transformation will point the way to a better understanding of the role of this miRNA in KSHV-associated tumors. IMPORTANCE Kaposi's sarcoma-associated herpesvirus (KSHV) is a human tumor virus. The viral Kaposin locus has known oncogenic potential, which has previously been attributed to the encoded KapA protein. Here we show that the virally encoded miR-K10a miRNA, whose precursor overlaps the KapA-coding region, may account for the oncogenic properties of this locus. Our data suggest that miR-K10a mimics the cellular miRNA miR-142-3p and thereby represses several known inhibitors of oncogenic transformation. Our work demonstrates that functional properties attributed to a coding region may in fact be carried out by an embedded noncoding element and sheds light on the functions of viral miR-K10a.
Marginal Bone Remodeling Around Dental Implants with Hexagon External Connection After 10 Years: A Case Series with 10 to 19 Years of Function

Field: Dentistry (Health Sciences)

Peri-implant bone remodeling occurs in all osseointegrated implants and can be defined as an adaptive process of bone around the implant in response to functional loading. This retrospective study evaluated the marginal bone remodeling around dental implants with external hexagonal connections in function for more than 10 years. The sample consisted of 17 implants placed in the posterior region of the mandible to replace one or several teeth. For all cases, the initial periapical radiograph was assessed together with a subsequent follow-up periapical radiograph. Image analysis was performed using ImageJ software to establish the initial bone measurements and subsequent bone loss. The data were statistically analyzed using paired t test at a significance level of 5%. There was significant bone remodeling when the baseline and follow-up were compared (P < .001). The mean values of peri-implant bone remodeling on the mesial aspect were 0.90 ± 0.63 mm vertically and 1.17 ± 0.60 mm horizontally. The distal aspect of the implants showed 1.01 ± 0.82 mm and 1.06 ± 0.75 mm of marginal bone remodeling vertically and horizontally, respectively. Within the limitations of this study, marginal bone remodeling was visible, and bone levels around the external hexagon implants remain stable after 10 years of function.
Five-year growth responses of Douglas-fir, western hemlock, and western redcedar seedlings to manipulated levels of overstory and understory competition

Field: Agricultural and Biological Sciences (Life Sciences)

Douglas-fir (Pseudotsuga menziesii (Mirb.) Franco), western hemlock (Tsuga heterophylla (Raf.) Sarg.), and western redcedar (Thuja plicata Donn ex D. Don) seedlings were planted in March 2001 within three clearcut-harvested, shelterwood, or thinned stands of mature Douglas-fir near Olympia, Washington. From 2002 to 2005, areas of vegetation control of 0, 4.5, or 9 m 2 were maintained with herbicides around a total 162 seedlings per species. Photosynthetically active radiation (PAR) was 34%, 62%, and 100% of full sunlight in thinned stands, shelterwoods, and clearcuts, respectively. Effects of overstory level and vegetation control on seedling growth and resource availability generally were additive. Seedling stem volume index in clearcuts averaged four to eight times that observed in thinned stands, and with vegetation control, it averaged two to four times that observed without it. In thinned stands, relative growth rate of seedling stem volume index had a positive linear relationship with PAR (R 2 = 0.38). Foliar nitrogen content of Douglas-fir explained 71% of the variation in relative growth rate. Factors explaining the most variation in foliar nitrogen content differed between thinned stands (PAR, R 2 = 0.34) and clearcuts or shelterwoods (midday water potential, R 2 = 0.63), suggesting that light and root competition, respectively, were the primary growth-limiting factors for these overstory levels.
Diversification strategies for hospital pharmacies

Field: Health Professions (Health Sciences)

Several ways used by the pharmacy department of a large university hospital to generate revenue through diversification are described. The department offers its facilities and staff as a resource in training medical service representatives for several pharmaceutical manufacturers, which is projected to provide $85,000 in net income for fiscal year (FY) 1983-84. The pharmacy department also conducts a six-month program for training pharmacy technicians, which yields a small net profit. The pharmacy department actively participates in educational programs such as college courses and clerkships earning extra income. An apothecary-style outpatient pharmacy was set up under a for-profit corporation. Services have been expanded to include the preparation of i.v. solutions that support home care. A durable medical equipment (DME) business is planned. The ambulatory and home-care programs are expected to generate approximately $165,000 in net profit next year. Contract pharmaceutical services are provided to another hospital. The net income generated through diversification in this pharmacy department will exceed $250,000 in FY 1983-84.
Learning a Style Space for Interactive Line Drawing Synthesis from Animated 3D Models

Field: Computer Science (Physical Sciences)

Most non-photorealistic rendering (NPR) methods for line drawing synthesis operate on a static shape. They are not tailored to process animated 3D models due to extensive per-frame parameter tuning needed to achieve the intended look and natural transition. This paper introduces a framework for interactive line drawing synthesis from animated 3D models based on a learned style space for drawing representation and interpolation. We refer to style as the relationship between stroke placement in a line drawing and its corresponding geometric properties. Starting from a given sequence of an animated 3D character, a user creates drawings for a set of keyframes. Our system embeds the raster drawings into a latent style space after they are disentangled from the underlying geometry. By traversing the latent space, our system enables a smooth transition between the input keyframes. The user may also edit, add, or remove the keyframes interactively, similar to a typical keyframe-based workflow. We implement our system with deep neural networks trained on synthetic line drawings produced by a combination of NPR methods. Our drawing-specific supervision and optimization-based embedding mechanism allow generalization from NPR line drawings to user-created drawings during run time. Experiments show that our approach generates high-quality line drawing animations while allowing interactive control of the drawing style across frames.
A CMOS time-multiplexed digital filter for vocoder applications

Field: Computer Science (Physical Sciences)

In vocoder systems speech is spectrally analysed with filter banks containing 16 to 19 narrowband filters. Digital techniques can be used to realize these filter banks in an economical manner by using single time multiplexed second order filters. A hardware implementation of a fourth and an eighth order filter, realized with one time-shared second order section is described. A software package is developed to simulate the filter performance, and validate the experimentally measured response. The CMOS design of a programmable filter is presented. A second order section is time multiplexed to realize up to 32 poles of filtering. The configuration is mask programmable and the filter coefficients are programmable with a UV-PROM. The bank of contiguous bandpass filters for vocoder use can be implemented with three multi-function filter chips.
Factors Influencing Sacco Members to Seek Services of Other Financial Service Providers in Kenya

Field: Economics, Econometrics and Finance (Social Sciences)

The primary aim of this study is to examine the factors that influence Sacco members in Kenya to seek financial products from other financial service providers. The study investigated the factors that make Sacco members to seek the services of other financial service providers. Saccos are saving and credit cooperatives societies. Saccos are quasi financial institutions that mobilize savings, provide loans as well as other products to their members. To achieve this objective, the study employed the survey involving a sample of 100 Sacco members drawn from 18,833 members of the 44 Saccos operating within Central Rift Valley Region of the cooperative society. Stratified Random sampling was used to select respondents and a questionnaire was used to collect data from Sacco members. Both descriptive and inferential statistics were used to analyze the data. Hypotheses were tested using correlation analysis and regression analysis. Correlation analysis tested the relationship between the independent variables and the dependent variable while regression analysis was used to determine the contribution of each independent variable to the dependent variable. The findings of the study revealed that a large number of Sacco members took loans offered at the Saccos in spite of the cut throat competition by other financial institutions and that the Saccos were not as competitive as other financial service providers in terms of processing and delivering of financial products, the type of products offered and customer relations .
Further Observations on the Potentiation of the Antibacterial Effect of Methenamine by Acetohydroxamic Acid

Field: Social Sciences (Social Sciences)

Abstract copyright UK Data Service and data collection copyright owner.

The Labour Force Survey (LFS) has been carried out in the UK since 1973. From 1973 until 1983 the survey was carried out biennially, and from 1984 until 1991 it was conducted annually. In 1992 the quarterly LFS was introduced. For full background and methodological information users should refer to the main Quarterly Labour Force Survey (QLFS) series (held at the UK Data Archive (UKDA) under GN 33246).

The Local Area Data series was produced quarterly alongside the main QLFS from 1992-2006, and included aggregated data on employment, economic activity and related subjects, covering Local Authority Districts (LADs), Training and Enterprise Councils (TECs), and their Scottish and Welsh equivalents. From 1992 until August 1997, the data covered Great Britain, and from September 1997 data from Northern Ireland were added. The Local Area Data were also available as an annual database between 1994-1995 and 1999-2000, for LADs at individual level, but these are no longer produced.

LFS move from seasonal to calendar quarters
In accordance with EU regulations, the LFS moved from seasonal (spring, summer, autumn, winter) quarters to calendar quarters (January-March, April-June, July-September, October-December) in 2006. The last seasonal Local Area Data dataset issued was the Quarterly Labour Force Survey, December 2005 - February, 2006: Local Area Data (SN 5392), and the first calendar quarter dataset was the Quarterly Labour Force Survey, January - March, 2006: Local Area Data (SN 5393). Users should note that there is some overlap between these two datasets. Further information on the seasonal to calendar quarter change and its impact on LFS data may be found in the following online article:
Madouros, V. (2006) Impact of the switch from seasonal to calendar quarters in the Labour Force Survey, London: ONS.

LFS Documentation
The User Guides available with the UK Data Archive's LFS studies are those available at the time of deposit. Users can access the updated guides online via the ONS LFS User Guide pages.
Correlated Multiplicative Modulation in Coupled Oscillator Systems: A Model of Selective Attention

Field: Neuroscience (Life Sciences)

We develop an oscillator model of selective attention based on spread spectrum communication. Stimulus intensity and attention are differentially encoded in the time average of phase velocities of sender oscillators and their temporal structure respectively. Receiver oscillators are driven by a mixture of phase velocities of the sender oscillators. With the aid of top-down modulatory signals that do not change the mean rotational velocity of sender oscillators, our proposed communication scheme allows the receiver oscillators to selectively correlate their velocity with the attended stimulus.
The effects of different exercise intensities on word learning strategies in healthy older adults: A word learning strategy investigation nested in a randomised controlled trial

Field: Psychology (Social Sciences)

<b>Background</b> - Traditional aphasia treatments can improve word retrieval difficulties in people with aphasia , however, therapy outcomes including the extent and duration of improvements can greatly vary between individuals. - Novel treatment approaches, such as a single bout of high intensity exercise, show the potential to enhance novel word learning performance - Effective word learning strategies have been shown to maximise novel word learning and novel word learning performance has been correlated with anomia treatment outcome
Elective Conversion from Cyclosporin to Azathioprine in Living Related Donor Kidney Transplants

Field: Medicine (Health Sciences)

Abstract Thirty-five patients with living related donor kidney transplants who were initially immunosuppressed with cyclosporin and a small dose of prednisolone were electively converted to receive azathioprine. Conversion was carried out 6 months after initiation of cyclosporin therapy. Cyclosporin was initially given as part of a random study in 13 cases (group I), and due to the presence of immunological high-risk factor(s) or to control steroid-resistant rejection episodes in 22 cases (group II). In group I, three cases developed acute rejection symptoms which were easily controlled. In group II, conversion was followed by acute rejection episodes in six patients. In two cases these were easily controlled. In four cases the episodes were unsuccessfully controlled, even after reintroduction of cyclosporin. We conclude that conversion from cyclosporin to azathioprine in living related donor kidney transplant patients at 6 months is a safe and beneficial practice in immunologically stable cases, but hazardous in those with high-risk immunological factors.
Preparation, properties, and drug release of thermo- and pH-sensitive poly((2-dimethylamino)ethyl methacrylate)/poly(N,N-diethylacrylamide) semi-IPN hydrogels

Field: Chemical Engineering (Physical Sciences)

In this paper, a series of semi-interpenetrating polymer network (semi-IPN) hydrogels based on poly((2-dimethylamino)ethyl methacrylate)/poly (N,N-diethylacrylamide) (PDMAEMA/PDEA) were synthesized by changing the initial PDMAEMA/DEA molar ratio at room temperature. The influence of this additive on the property of resulting PDEA hydrogels was investigated and characterized. The interior morphology by scanning electron microscopy (SEM) revealed that the semi-IPN hydrogels have interconnected porous network structures. The glass transition temperature (T (g)) of the semi-IPN hydrogels was observed by differential scanning calorimetry (DSC). Equilibrium swelling ratio (ESR), swelling and deswelling dynamics of the hydrogels responding to temperature and pH were investigated in detail. Compared to PDEA, the semi-IPN hydrogels exhibited excellent mutative values in response to an alternation of the temperature and pH, and showed fast swelling and deswelling rates in response to temperature and pH change. The release behaviors of the model drug, aminophylline, were found dependent on hydrogel compositions and environmental temperature. These results suggest that the stimuli semi-IPN hydrogel have potential application as intelligent drug carriers.
SUN-275 DOSE EQUIVALENCY AND EFFICACY OF BIOSIMILAR ERYTHROPOIETIN STIMULATING AGENTS: DATA FROM REAL CLINICAL PRACTICE

Field: Medicine (Health Sciences)

Renal anemia is a common complication of end stage renal disease (ESRD) that require continuous replacement therapy with recombinant human erythropoietin stimulating agents (rESA) in most patients. Biosimilar erythropoietin stimulating agents (bESA) are available in Kazakhstan and that most of the dialysis centers switched their patients into the more cost effective bESA. However, important properties of bESA such as dose equivalency to rESA and the ability to maintain hemoglobin (HB) target levels were unknown.
Motifs in the amino-terminus of CENP-A are required for its accumulation within the nucleus and at the centromere

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Centromere protein A (CENP-A) is a variant of core histone H3 that marks the centromere's location on the chromosome. The mechanisms that target the protein to the nucleus and the centromere have not been defined. In this study, we found that deletion of the first 53 but not the first 29 residues of CENP-A from the amino-terminus, resulted in its cytoplasmic localization. Two motifs, R42R43R44 and K49R52K53K56, which are reported to be required for DNA contact in the centromere nucleosome, were found to be critical for CENP-A nuclear accumulation. These two motifs potentially mediated its interaction with Importin-β but were not involved in CENP-A centromeric localization. A third novel motif, L60L61I62R63K64, was found to be essential for the centromeric accumulation of CENP-A. The nonpolar hydrophobic residues L60L61I62, but not the basic residues R63K64, were found to be the most important residues. A protein interaction assay suggested that this motif is not involved in the interaction of CENP-A with its deposition factors but potentially mediates its interaction with core histone H4 and CENP-B. Our study uncovered the role of the amino-terminus of CENP-A in localization.
A large dataset of real patients CT scans for COVID-19 identification

Field: Medicine (Health Sciences)

We describe a publicly available multiclass CT scan dataset for SARS-CoV-2 infection identification. Which currently contains 4173 CT-scans of 210 different patients, out of which 2168 correspond to 80 patients infected with SARS-CoV-2 and confirmed by RT-PCR. These data have been collected in the Public Hospital of the Government Employees of Sao Paulo (HSPM) and the Metropolitan Hospital of Lapa, both in Sao Paulo - Brazil. The dataset is composed of CT scans in png format, which are divided into: 758 CT scans for healthy patients (15 CT scans per patient on average). 2168 CT scans for patients infected by SASR-CoV-2(27 CT scans per patient on average). 1247 CT scans for patients with other pulmonary directions (16 CT scans per patient on average). TOTAL: 4173 CT scans for 210 patients of Sao Paulo - Brazil (20 CT scans per patient on average).