jimnoneill/paper-to-field-training huggingface dataset:
Brain Imaging and Sculptural Plasticity

Field: Arts and Humanities (Social Sciences)

This article proposes to explore, through a series of intra-connected examples drawn from art and culture, an alternative imaging of brain plasticity. Taking influence from current discourses on the brainbody phenomenon (Schmitz and Hoppner, 2014; Schmitz, 2015, Pitts-Taylor, 2016), a diffractive methodology of reading will be explored through the mediations of the brain in culture, that is, through specific curatorial and artistic mechanisms which have sought to think the historical and contemporary technologies and apparatuses of neuroscience otherwise. \n \nThere are five key examples that help to situate the phenomenon of plasticity as the reception, production and annihilation of form in the worlds of art and culture, with the aim of revisiting the brain image from out of these spaces. The first presents a scientific-anthropological account of how PET scanning works, in particular, how a brain image is constructed from the technical and scientific processes involved. This provides a particular way of understanding the brain-as-image. The second provides a comparative analysis between different types of brain culture within exhibition environments. This draws upon the discourses of exchange between cultural artefacts, neuroscience and learning. The third example looks to the curatorial strategies deployed by Caroyln Christov-Bakargiev, in particular, the form iterations generated out of dOCUMENTA (13) (2012) and the 14th Istanbul Biennial SALTWATER: A Theory of Thought Forms (5 September-1 November 2015). These international exhibitions engage with a diffractive methodology of reading through the intra-active exchanges between art, neuroscience and neuroaesthetics in particular. The fourth example explores a recent film by Ursula Biemann entitled Twenty One Percent (2016). This is a return to the brainbody phenomenon and to the articulations of agential matter through the chemical compound structure of the body and its intra-celestial relationship to the universe. Biemann’s video essay will be considered as a specific type of diffractive reading which works inside the body. The final example makes a return to brain imaging technology in the context of The Human Connectome Project, to the ways in which a reading of this brain – as a collective speculative fiction of newly discovered regions – might think neuronal imaging otherwise, beyond the formal necessity of the brain imaging environment and into the spaces of our embodied imaginations. These are projects which have sought to explore the intersections between art and science, and which lend themselves to a reading that is entangled with differing perspectives and disciplines.
[Hypochondriasis. Symptom at the crossroad or a road crossing the syndromes?].

Field: Medicine (Health Sciences)

Even if widely described, hypochondriasis remains a multidimensional concept which has to be carefully reconsidered: different meanings are indeed involved in its use, coming from historical and classical psychiatry, and from psychoanalysis as well as from the new trends in psychosomatic medicine and liaison psychiatry. The syndrome/symptom confusion has to be avoided. It also appears that some light should be shed on the concept of the term "hypochondriasis", which has been used abusively in modern psychiatry.
Rivaroxaban With or Without Aspirin in Patients with Stable Peripheral or Carotid Artery Disease

Field: Medicine (Health Sciences)

Abstract This chapter provides a summary of a landmark study in the management of patients with atherosclerotic vascular disease. The Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) trial assessed the role of rivaroxaban in decreasing major adverse cardiovascular events. The COMPASS trial demonstrated better efficacy for a combination of low-dose rivaroxaban and aspirin than aspirin alone or rivaroxaban alone. This chapter describes the basics of the study, including funding, study location, who was studied, how many patients were recruited, study design, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, gives a summary and concludes with a relevant clinical case.
SUN-237 Clinical Outcomes after Adrenalectomy in Primary Aldosteronism

Field: Medicine (Health Sciences)

Abstract Disclosure: K. Zekarias: None. J. Kohlenberg: None. M. Johnston: None. S. Ikramuddin: None. Background: Previous studies have reported complete clinical cure, defined as normalization of blood pressure without antihypertensive medications, in 37-39% of patients (1-2) following adrenalectomy for primary aldosteronism (PA), based on the former blood pressure (BP) threshold of &lt;140/90 mmHg. This study evaluated outcomes using the current guideline BP threshold of &lt;130/80 mmHg. Methods: We performed a retrospective analysis using the Epic COSMOS database, a multi-institutional repository of de-identified electronic health records. Using International Classification of Disease (ICD) codes, we identified 1,320 patients who underwent laparoscopic adrenalectomy for primary aldosteronism between January 2013 and December 2024. Inclusion required preoperative aldosterone measurement and office BP readings within 6 months before and 6-18 months after surgery (n=1,098). After excluding patients with baseline BP &lt;130/80 mmHg and no antihypertensive medications, 1,079 patients were analyzed. Results: In this cohort, the mean age was 53.0±11.9 years, 40% female, complete clinical success (blood pressure &lt;130/80 mmHg without medications) was achieved in 16% (178/1079) of patients. Partial success, defined as reduction in antihypertensive medications, occurred in 57% (615/1079), while 17% (180/1079) remained on the same number of medications. Multivariate logistic regression analysis showed that more antihypertensive medications (p &lt; 0.001), higher blood pressure (systolic p = 0.004, diastolic p = 0.010), and greater social vulnerability (p = 0.013) predicted lower clinical success. Age, gender, race, body mass index, stroke history, sleep apnea, baseline potassium, and glomerular filtration rate showed no significant associations (all p &gt; 0.05).Our study has limitations inherent to EHR data analysis: documentation inconsistencies across institutions, incomplete data capture, and potential selection bias from analyzing only Epic-based healthcare facilities may limit result generalizability. Conclusions: When applying current BP guidelines, complete clinical success following adrenalectomy for PA occurs in a smaller proportion of patients than previously reported. These findings enable physicians to provide realistic expectations and emphasize the need for vigilant post-surgical BP monitoring and management.References: 1. Williams TA, et al; Primary Aldosteronism Surgery Outcome (PASO) investigators. Lancet Diabetes Endocrinol. 2017;5(9):689-699. 2. Marzano L, et al. Hypertens Res. 2024;47(3):721-734. Presentation: Sunday, July 13, 2025
Nutrient Testing of Soils to Determine Fertilizer Needs on Central Sierra Nevada Deer-Cattle Ranges

Field: Agricultural and Biological Sciences (Life Sciences)

Soil samples representing six major forest soil series and two meadow unclassified types were collected from 17 locations on critical deer migration routes in the central Sierra Nevada, California. Nutrient tests were conducted in the greenhouse using soft chess (Bromus mollis) as an indicator species to determine deficiencies of nitrogen, phosphorus, and sulfur. These tests were carried out to assess fertilizer needs and the probability of field response to increased nutrient levels in the soil for improvement of forage quality and quantity on deer migration routes. All soils were nitrogen deficient; the meadow soils were less so than the forest soils. In 94% of the soils samples, the addition of phosphorus (70%) or phosphorus and sulfur (24%) with nitrogen increased plant yields dramatically (as much as 26 times) compared with adding nitrogen alone. Addition of sulfur with nitrogen produced a yield response equal to that produced by phosphorus or phosphorus plus sulfur with nitrogen in three soils. Nitrogen was the nutrient most limiting for plant growth; phosphorus was next important and was essential for best response in most soils. Sulfur produced variable responses, usually increasing plant yields only after nitrogen and phosphorus deficiencies were corrected. Productivity of forage and browse species growing on these soils is determined by nutrient status; characteristics delineated at the series level, such as depth, texture, and structure; and moisture-temperature relations in specific years.
Factors causing employees to resign from foreign oil company in China National Oil Offshore Corporation South East Sumatra (CNOOC SES Ltd.)

Field: Business, Management and Accounting (Social Sciences)

This study was conducted to determine and analyse the influence of organisational culture, work-life balance (WLB) and work pressure on employee engagement and employee turnover intention. This research uses a quantitative approach using structural equation modelling (SEM) and surveys. The population used is CNOOC SES Ltd. employees which amounted to 574 people. This research was tried in January to August 2018. This research was tried out at the CNOOC SES Ltd. Office, which is located at Indonesia Stock Exchange Tower 1 floor 19-23 JendralSudirmanKav 52 Jakarta, 12190, Indonesia. The findings in this study are that there is a significant and positive influence between company culture and WLB on employee engagement and there is a significant and negative influence between work pressure on employee engagement.
Transcriptomics Study on Staphylococcus aureus Biofilm Under Low Concentration of Ampicillin

Field: Immunology and Microbiology (Life Sciences)

Staphylococcus aureus is one of the representative foodborne pathogens which forms biofilm. Antibiotics are widely applied in livestock husbandry to maintain animal health and productivity, thus contribute to the dissemination of antimicrobial resistant livestock and human pathogens, and pose a significant public health threat. Effect of antibiotic pressure on S. aureus biofilm formation, as well as the mechanism, remains unclear. In this study, the regulatory mechanism of low concentration of ampicillin on S. aureus biofilm formation was elucidated. The viability and biomass of biofilm with and without 1/4 MIC ampicillin treatment for 8 h were determined by XTT and crystal violet straining assays, respectively. Transcriptomics analysis on ampicillin-induced and non-ampicillin-induced biofilms were performed by RNA-sequencing, differentially expressed genes identification and annotation, GO functional and KEGG pathway enrichment. The viability and biomass of ampicillin-induced biofilm showed dramatical increase compared to the non-ampicillin-induced biofilm. A total of 530 differentially expressed genes (DEGs) with 167 and 363 genes showing up- and down-regulation, respectively, were obtained. Upon GO functional enrichment, 183, 252, and 21 specific GO terms in biological process, molecular function and cellular component were identified, respectively. Eight KEGG pathways including "Microbial metabolism in diverse environments", "S. aureus infection", and "Monobactam biosynthesis" were significantly enriched. In addition, "beta-lactam resistance" pathway was also highly enriched. In ampicillin-induced biofilm, the significant up-regulation of genes encoding multidrug resistance efflux pump AbcA, penicillin binding proteins PBP1, PBP1a/2, and PBP3, and antimicrobial resistance proteins VraF, VraG, Dlt, and Aur indicated the positive response of S. aureus to ampicillin. The up-regulation of genes encoding surface proteins ClfB, IsdA, and SasG and genes (cap5B and cap5C) which promote the adhesion of S. aureus in ampicillin induced biofilm might explain the enhanced biofilm viability and biomass.
Private Sector Engagement Policies in South Korea: Challenges and Policy Recommendations

Field: Social Sciences (Social Sciences)

Abstract The Korean government recently announced a strategy for engaging the private sector in international development. There are expectations that this will attract innovative solutions with more financial resources, but, on the other hand, there are concerns that private companies will only focus on pursuing commercial interests without paying attention to the normative legitimacy such as private sector development in partner countries. There are also concerns that fragmentation will further deepen as ODA funds are divided due to mutual non-interference among various actors. Finally, this study discusses policy implications for Korean private companies to be development agents which are derived from the case of German private sector engagement.
The Impact of Mergers on Quality Provision: Evidence from the Airline Industry

Field: Economics, Econometrics and Finance (Social Sciences)

We examine how mergers affect quality provision by analyzing five U.S. airline mergers, focusing on on‐time performance (OTP). We find that airline mergers have minimal negative impacts on OTP, and likely result in long‐run improvements due to efficiencies. Importantly, we show that this finding is not driven by post‐merger changes in price that could affect OTP. Consequently, at least in the case of airlines, policymakers should not, as a rule, fear the negative quality effects of mergers.
Studies of accuracy during protein synthesis involving the E-tRNA and the Shine-Dalgarno interaction

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The ribosome contains three tRNA binding sites, the A, P and E sites. Although the E site is separated\nfrom the A via the intervening P site, there is a striking communication between these sites. This crosstalk\nplays an important role for the accuracy of the decoding process. Codon-anticodon interaction at the\nE site seems to be the signal to switch into the post-translocational (POST) state characterized by a low\naffinity of the A site. This low affinity state forces the ternary complexes aminoacyl-tRNA•EF-Tu•GTP to\nenter the A site via the decoding center preventing the selection of non-cognate aminoacyl-tRNAs and\nincorporation of the amino acid. This has the important consequence that only 1 in 400 misincorporations\naffects protein functions. Another aspect of the three tRNA binding sites is that at least two\ntRNAs are present on the ribosome. Since the tRNAs are firmly bound by the ribosome whereas the\nmRNA practically only via codon-anticodon interaction during the elongation phase, the movement of the\ntRNA during translocation pulls the mRNA through the ribosome. In fact, the six base pairs of two\nadjacent codon-anticodon interactions are instrumental for maintaining the reading frame. Without the\ncodon-anticodon interaction of the E tRNA the reading frame would be lost at least after the incorporation\nof about 50 amino acids into the nascent chain.
VARIATION IN MECHANICAL PROPERTIES WITHIN AND BETWEEN PLANTATION-GROWN GMELINA ARBOREA TREES

Field: Agricultural and Biological Sciences (Life Sciences)

Recent studies have shown that the material properties of Gmelina -a fast-growing hardwood species, are comparable with those of European-grown softwood species and are suitable for construction purposes.Information on the variation in the material properties which could aid the end use, such as sorting the logs with respect to end user requirement, is lacking.This work is an investigation into the variation of the mechanical properties along the height and between different Gmelina trees, to aid an efficient and effective end use of the material.10 material properties were experimentally and statistically investigated.The results showed that the material properties of Gmelina do not vary along its height as much as is observed for other timber species.Between the trees, a variation range of 11 -14 % was determined.
Sex, Dating, Passionate Friendships, and Romance: Intimate Peer Relations Among Lesbian, Gay, and Bisexual Adolescents

Field: Psychology (Social Sciences)

Although the raw number of adolescent romantic and sexual involvements is well documented, the actual experience and meaning of these relationships for adolescents receives little attention. As a result, these relationships are frequently classed together on the basis of surface similarities, despite important structural and functional differences. Attention to these differences, however, reveals how young men and women craft adaptive constellations of peer relationships to meet changing needs for intimacy and social support during the multiple transitions of adolescence. In this chapter we put forth a typology of intimate peer relationships based on the motives prompting adolescents to pursue them, their specific characteristics, and the functions they serve. We specify four varieties of adolescent relationships – sexual relationships, dating relationships, passionate friendships, and romantic relationships – representing prototypical combinations of some of the most salient motives, characteristics, and functions.
Ultrastructural Alterations and DNA Synthesis of Renal Cell Nuclei following Cisplatin or Carboplatin Injection in Rats

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Abstract To clarify the difference in nephrotoxicity between cisplatin and carboplatin, ultrastructural alterations and DNA synthesis of renal cell nuclei were studied in Sprague-Dawley rats which had received intravenously either cisplatin or carboplatin at an equitoxic dose. Twelve hours after cisplatin injection, nucleolar segregation accompanied by aggregated nuclear heterochromatin was observed in the third segment of the proximal tubules. Seventy-two hours after cisplatin injection, nuclear damage was more widespread while regenerative cells were also observed. Nuclear damage was not observed in the carboplatin-treated rats. Nuclear DNA synthesis of renal cells was suppressed at 8, 12 and 24 h and was accelerated at 72 h after cisplatin injection. Carboplatin did not suppress nuclear DNA synthesis at any time. The results indicate that cisplatin, but not carboplatin, can affect the renal cell nuclei. Cisplatin-induced nephrotoxicity is related to its effects on renal cell nuclei.
Establish of the orthotopic human pancreatic cancer model in mice and high frequency probe of endoscopy ultrasonographic monitoring

Field: Medicine (Health Sciences)

Objective To establish the orthotopic human pancreatic cancer model in mice and study the method to detect the tumor growth. Methods Human pancreatic cancer cell lines SW1990 in logarithmic phase was made into cell suspension and in situ injected into the envelope of pancreatic tail of BALB/c nude mice. High-frequency endoscopy ultrasound was used to observe the growth of tumor mass and its imaging characteristics were studied. Results 20 nude mice were successfully implanted, and 1 died 25 h after implantation. 14 days after implantation, the tumor of pancreatic cancer on EUS was (8.09 ± 2.61) mm3, the tumor appeared as homogeneous hypoechoic mass with clear boundary, and envelope as well as sound halo was present, and the shape was regular; there was low speed circular vasculature signal in around 30% of tumor.The tumor size increased to (12.40 ± 3.51)mm3, and the shape of 70% tumor was irregular, and some appeared as lobulated, and the tumor appeared as heterogeneous hypoechoic mass, no necrosis or liquefaction was found 28 days after implantation. There was low speed circular vasculature signal in around 70% tumors.Conclusions The orthotopic pancreatic cancer model in nude mouse can be established by in situ injection and this method is relatively ideal because it is simple and effective. The high frequency probe of endoscopic ultrasonograph is a reliable method for monitoring implanted pancreatic cancer.

Key words:
Pancreatic neoplasms; Model,animal; Endoscopy Ultrasonography
Workload indexed blood pressure response to ramp exercise across intensity domains

Field: Medicine (Health Sciences)

During exercise, systolic blood pressure (SBP) increases due to rising cardiac output and vascular resistance. The slope of SBP relative to power output (ΔSBP/ΔW) has been proposed as a marker of cardiovascular risk, but whether this relationship varies across exercise intensity domains remains unclear. This study aimed to determine if ΔSBP/ΔW differs across moderate, heavy, and severe exercise intensity domains and whether domain-specific analysis offers added insight compared to the overall response. Thirteen healthy adults (21 ± 2.7 yrs; 7F/6M) completed a graded ramp cycling test to task failure, followed by a 3-minute all-out test to estimate critical power (CP). Exercise domains were defined individually as moderate (< gas exchange threshold, GET), heavy (between GET and CP), and severe (> CP). Beat-by-beat SBP was recorded via finger photoplethysmography, and ΔSBP/ΔW was calculated within each domain and for the overall test. Data were analyzed using mixed-effects linear modeling. No significant differences in ΔSBP/ΔW were observed between domains or compared to the overall response. However, within-domain variability was greater in the heavy (CV=0.76) and severe (CV=0.73) domains compared to moderate (CV=0.55). On average, SBP rose from 131 ± 11.1 mmHg at rest to 179 ± 38.5 mmHg at peak. CP occurred at 82% of VO₂peak, with average CP and VO₂peak values of 184 ± 62 W and 36 ± 9.2 mL/kg/min, respectively. While ΔSBP/ΔW did not differ significantly across intensity domains, increased variability in the heavy and severe domains suggests that individual cardiovascular responses may be more nuanced than overall trends reveal. This highlights the potential value of domain-specific analyses for identifying abnormal blood pressure responses that could indicate elevated cardiovascular risk, especially in populations with varied fitness levels. Further research in larger and more diverse cohorts is warranted to refine the use of workload-indexed SBP as a clinical tool.