jimnoneill/paper-to-field-training huggingface dataset:
Tourism potential analysis of the castles of Vinalopó, Spain: an opportunity for social and tourist development of cultural heritage

Field: Social Sciences (Social Sciences)

Within the overall framework of the renewal process of coastal tourist destinations, cultural heritage has frequently been used as a key argument for the introduction and development of strategies for the diversification and differentiation of the traditional tourist product based on sun and sand. This is the situation of the province of Alicante, identified with the Costa Blanca geotourism brand, where there are important economic issues that could contribute to the renewal of this coastal tourist destination. One of the most significant heritage values of this space consists of a series of medieval fortresses located along the axis of the Vinalopó River, which has acted since prehistoric times as a natural route from within the provincial mainland to the coast. It is precisely the argument of this historical, territorial and landscape content that has been used repeatedly in recent years to develop initiatives aimed at the creation of a tourist product, currently inexistent, based on the route of the castles of Vinalopó. This communication aims to analyse the degree of tourism potential of the fortresses located in the towns of Biar, Banyeres de Mariola, Sax, Villena, Novelda, Elda, Petrer and Elche, which constitute the core of municipalities where these medieval fortresses are located, finally pointing out some proposals for the creation of a heritage tourism product.
Tigranakert of Artsakh

Field: Arts and Humanities (Social Sciences)

Tigranakert of Artsakh is situated in the Askeran region of the Republic of Artsakh (former Nagorno Karabakh Autonomous Region), in the lower valley of Khachenaget, the second-largest river of the highlands. Occupying an area of more than 70 ha, it is spread over the south-western lower slope of Mt Vankasar and in the plain next to it (Figure 1), in the neighbourhood of the freshwater sources called ‘Shahbulagh’ (‘Royal Sources’). The city was founded at the end of 90s BC by the Armenian King, Tigranes II the Great (95-55 BC). The Artsakh expedition of the Institute of Archaeology and Ethnography of the National Academy of Sciences of Armenia found traces of the city in 2005, and thus far has realised archaeological excavations in its vicinity. Tigranakert of Artsakh is the only one among numerous settlements named after Tigranes that has been precisely located and is being investigated by archaeologists. The archaeological museum of the city was founded in 2010, based on the large amount of excavated archaeological material. Tigranakert is the most visited archaeological site in Artsakh, described in detail on the Internet, and is widely known within scientific circles and the public. The investigations of Tigranakert were undertaken and financed by the ‘Yerkir’ Union of Non-Governmental Organisations for Repatriation and Settlement. Since 2008, the archaeological investigation of the site has been financed by the government of the Republic of Artsakh.
Manheimia Haemolitica A1’E ait LktA ile Pasteurella Multocida A:3’E AİT PlpEC VE OmpH’den oluşan rekombinant aşı adaylarının geliştirilmesi.

Field: Veterinary (Health Sciences)

Mannheimia haemolytica A1 and Pasteurella multocida serotype A:3 are gramnegative bacterial pathogens which are considered the causative agents of bovine respiratory disease (BRD) or shipping fever in cattle. The foremost of several virulence factors of M. haemolytica A1 which allows lung colonization and establishment of infection is leukotoxin (Lkt). The others include adhesin, capsule, outer membrane proteins, and various proteases used for attachment, spreading and evading innate and adaptive host immune responses. Similarly, the major virulence factors of P. multocida are capsule, lipopolysaccharide (LPS), toxin (PMT), outer membrane proteins (OMPs), especially PlpE and OmpH, adhesins and type IV fimbriae (pili). BRD has considerable economic importance to the global cattle and feedlot industry. Effective control of BRD is challenging due to inconsistencies in diagnosis and treatment regimes. Extensive antibiotic usage in cattle industry, both prophylactically and therapeutically, leads to development of antibiotic resistance. Therefore, development of vaccine strategies against BRD to demonstrate protection becomes an important issue for cattle industry. P. multocida A:3 lipoprotein E (PlpE) and outer membrane protein H (OmpH) and M. haemolytica A1 leukotoxin (LtkA) have been selected as the antigens for vaccine development studies in our laboratory. PlpEC-OmpH and OmpH-LktA recombinant fusion proteins were previously constructed, expressed and purified. When PlpEC-OmpH was used as an universal vaccine candidate in combination with a mineral oil-based CpG adjuvant, it conferred 100% protection against P. multocida A:3 in BALB/c mice. In the present study, OmpH-Lkt recombinant protein was formulated as an oil-based vaccine candidate and BALB/c mice were immunized with this vaccine formulation. In two independent sets of mice challenge-protective potency experiments for each pathogen, %100 and %50 protection was demonstrated against M. haemolytica A1 and P. multocida A:3, respectively. Additionally, lktA fragment was cloned from the genomic DNA of M. haemolytica A1 at the upstream of plpEC-ompH fusion and the resulting lktA-plpEC-ompH triple fusion was constructed. In vitro expression of this fusion was shown in E.coli BL21 (D3) cells and the purified protein was used for vaccine preparation. The vaccine candidate comprising LktA-PlpECOmpH was formulated with a mineral oil-based adjuvant and the sera collected from the immunized mice were used for the determination of specific antibody and serum IFN-γ titers. Although the antigen-specific IgG1 and IgG2a levels were higher in immunized group, there was no significant difference between control and immunized mice groups in terms of IFN-γ levels. Protective capacity (potency) of this vaccine candidate was also evaluated via mice challenge experiments with lethal doses of P. multocida A:3 and M. haemolytica A1 separately, which did not give consistent results in two independent sets of experiments for each pathogen.
Haplotype‐resolved genome assembly provides new insights into the genomic origin of purple colour in Prunus mume

Field: Agricultural and Biological Sciences (Life Sciences)

Summary Prunus mume , an important ornamental woody plant in the Rosaceae family, contains many interspecific hybridizations. Purple colour is a breeding trait of aesthetic value for P. mume , but little is known about the origin and genetic architecture of this trait. Here we address these issues by producing a haplotype‐resolved genome from an interspecific hybrid cultivar of P. mume (M) and P. cerasifera ‘Pissardii’ (C), named P. mume ‘Meiren’, followed by a detailed molecular characterization. The final length of the diploid genome is 499.47 Mb, with 250.66 Mb of haplotype M (HM) and 248.79 Mb of haplotype C (HC). Approximately 95.42% (476.61 Mb) of the phased assembly is further anchored to 16 homologous chromosomes. Based on the genomic variation, we identify a 1.8 Mb large‐fragmented inversion (INV) on chromosome 1b of HC, which co‐segregates with purple colour traits of ‘Meiren’ inherited from its purple C parent ‘Pissardii’. We find that a MYB transcription factor, PmmMYB10.5b , resides at the distal breakpoint of the INV, which displays consistent allele‐specific expression (ASE). By directly binding to the promoter of anthocyanin synthetic alleles, PmmMYB10.5b serves as a co‐activator to promote anthocyanin accumulation in ‘Meiren’ organs. Notably, the INV identified in ‘Meiren’ is generated from ‘Pissardii’ rather than P. cerasifera , which alters the promoter sequence of PmmMYB10.5b , activates its expression and results in the purple colour trait. Results from this study shed light on the evolutionary origin of purple colour in ‘Meiren’ and could potentially provide guidance on the genetic improvement of colour traits in ornamental woody plants.
Exploitation of solar energy for the elaboration of zinc oxide thin films according to a new method of solar spray pyrolysis

Field: Energy (Physical Sciences)

The deposition of thin films is done by several methods such as physical process (PVD), chemical process (CVD), spray pyrolysis is part of these methodes, where heat is required as the main factor, in this work we used the sun as a source of heat. For this purpose a parabolic concentration system was used, which offers the possibility to produce heatfrom solar energy, where temperatures can easily exceed 800°C and the conversion efficiency is high generally. By exploiting direct solar radiation, considered the main resource, which is very considerable on a planetary scale, this technology offers a real alternative to the consumption of fossil resources with a low environmental impact and a strong potential for cost reduction. The parabolic geometry of this device allows all the light rays falling on the surface of the parabola to be concentrated in one point where the cooking dish is placed (focus). The power of this device depends of course on the size of the parabola. The elaboration of the thin layers based on zinc oxide is done at well determined conditions, allows these conditions the temperature, where it is chosen at400C°. for that, a geometrical study on the parabolic solar concentrators was made to determine the various parameters which allow to wait for this temperature with the solar radiation of 950 W/m 2 [1]. after the dimensioning of the concentrator one elaborated a series of ZnO to see their effectiveness
Extension of the genus Pseudopeas (Dysopeas) (Gastropoda: Subulinidae) from Venezuela to Nicaragua

Field: Agricultural and Biological Sciences (Life Sciences)

The study of Nicaraguan land snails is fragmentary. Recent sampling produced specimens of an undetermined species of Pseudopeas Putzeys, 1899. This genus was segregated from Opeas Albers, 1850 by reason of its prominent rib sculpture and later re-de- scribed by Pilsbry (1906) for the characteristic spiral sculpture of its nepi- onic whorls. Baker (1927) named a new subgenus Dysopeas for species where the spiral sculpture covers the entire shell, not only the nepionic whorls. The Nicaragua specimens show nepionic and body sculptures that precisely match descriptions and illustrations given by Pilsbry and Baker for the complex Pseudopeas/Dysopeas. Since 1999, a total of 160 specimens have been collected from El Castillo on Río San Juan, Isletas de Granada and the Universidad de las Regiones Autónomas de la Costa Caribe Nicaragüense (URACCAN) in Blue elds. Similitude with some sculpture traits and protoconch development with species of Spiraxidae, Subulinidae or Lamellaxis might cause confusion in the determination of Pseudopeas. Besides the critical protoconch sculpture and pro le, additional discriminatory di erences from these look-alikes are dimensions, sculpture pattern and crystalline structure.
Analisis Penggunakan E-Wallet Dalam Bertransaksi Keuangan Mahasiswa Universitas Sultan Maulana Hasanuddin Banten

Field: Business, Management and Accounting (Social Sciences)

Internet users are growing rapidly from time to time all over the world, including Indonesia. As a result, their consumer's need for making payments has changed to non-cash payments, namely electronic wallets, which are becoming a huge potential in their e-commerce market. Their preference for e-wallet transactions increases compared to using cash. Most of its users are millennials, including students. This study has knowledge relevant to the use of e-wallets and the reasons behind their use. Their study involved college students, which consisted of nine female students, and one male student whose ages varied between 19 and 23 years. This study uses a quantitative method with an in-depth approach as a technique for collecting primary data and secondary data obtained from related websites. The results of this study yielded the following data: 1. Student knowledge about e-wallets has a positive and significant impact on student transaction interest based on the results, the t count is 10,160, which is greater than the t table, which is 1,989. 2. From the results of the deitemination coefficient test, it can be seen that the variable effect of student knowledge about e-wallets on interest in financial transactions is as much as 52.3%. This can be seen from the R value of squiarei in the variable knowledge of students about Islamic banks, which is equal to 0.523. The remaining 47.7% is affected by variables that are not included in the research being studied. On the other hand, e-wallets are not only understood as a place to store money electronically, but also as digital payments such as OVO, Gopay and DANA. and students not only feel comfortable, but also make payments easier because they can be done anywhere as long as the user is connected to the internet.
Политико-психологический профиль Трампа в предвыборной кампании 2024: предвзятость цифровых медиа и поляризация общества

Field: Social Sciences (Social Sciences)

Drawing upon original programs for processing an array of publications (n=1000) and analyzing the tonality of articles published from November 15, 2022 to March 30, 2023 on twenty digital platforms of various ideological leanings, the article examines the bias of these platforms towards Donald Trump with the intent to identify the predominant agenda in the US digital media from the official announcement of D. Trump’s entry into the 2024 presidential race until the filing of charges against him. The assumption is increasing media bias begets political polarization in society and radicalization of citizens’ political preferences. Research shows that left-wing media, the largest part of the digital media sphere, demonstrate the highest negative bias towards D. Trump, centrist media, ranking second, demonstrate a positive attitude towards the left agenda and acquire characteristics of clearly pro-Democratic platforms, and right-wing, the least popular, demonstrate equal levels of negative and positive bias, striving for constructive criticism of their political favourite. Thus, most US media, regardless of their declarations, broadcast political messages of a high level of negative bias towards the Republican candidate, seeking to influence the perception of D. Trump’s political psychological profile to benefit their editorial boards and owners.
Outpatient phototherapy for psoriasis

Field: Medicine (Health Sciences)

• Using a new protocol with varied exposure increments, we found that, in 18 of 20 patients with psoriasis vulgaris who were given ultraviolet (UV)-B phototherapy three times a week, the disease completely cleared. One patient's condition substantially improved, and one patient's condition failed to respond. Ten to 38 treatments were required during a three- to 13-week period. The only topical treatment agent used was white petrolatum. The results are compared with a schedule using five treatments a week and fixed UV-B-exposure increments. Infrequent (three times weekly) treatments, avoidance of hospitalization and crude coal tar treatment, and fewer episodes of UV-radiation burn may offer advantages for selected patients. Long-term effects and maintenance requirements for this treatment regimen are not known. (Arch Dermatol1981;117:623-626)
Organization and Management of Language Arts Teaching: Classroom Environments, Grouping Practices, and Exemplary Instruction

Field: Social Sciences (Social Sciences)

A major concern of teachers is organization and management of their language arts programs. Teachers are able with appropriate professional development to integrate cutting-edge strategies into their literacy curriculum, but have a difficult time putting the different pieces of the program together in their school day. In this chapter we attempt to review research that could help professionals with management issues. We examine research areas specifically dealing with the organization and management of language arts instruction, and also focus on theory and research about exemplary practice in the language arts, since this line of work can inform and improve organization and management of language arts teaching. Our purpose is to raise awareness, provide implications for classroom practice, and suggest topics for future research. To accomplish this goal, this chapter is divided into topics that answer some of our questions concerning research on the organization and management of language arts programs:1. How is student behavior and achievement affectedby the physical designof the classroom environment, for example, how are space andmaterials used in language arts instruction?
MRSA Defenses Found

Field: Immunology and Microbiology (Life Sciences)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Role of Endophytes in Apple Replant Disease

Field: Agricultural and Biological Sciences (Life Sciences)

Apple replant disease (ARD) is a major problem in all the apple-growing areas of the world. It is a complex problem. The exact cause of the problem is unknown, but soil biotic factors play a major role. The repeated cultivation of same crop on same land and exhaustion of nutrients of soil, persistence of soil-borne pathogens and changes in the pH of soil. Symptoms include stunting of tree growth with short internodes, small and light green rosette leaves, development of few lateral or feeder roots, underdeveloped root systems, decayed and discolored roots, poor establishment and severe disease results in the death of young trees and, sometimes, whole orchards. The endophytes provide direct benefits to host plants as they live in close proximity. Once they enter inside the host tissue they get easily established as they feel no competition with other microorganisms. Endophytes have the capacity to produce different secondary metabolites, which saves the host plants from biotic and abiotic stresses the host plants become resistant to both biotic and abiotic stresses. An interesting facet of the interaction between endophytes and their hosts is the capacity of many microorganisms to improve the plant’s resistance by providing several bioactive metabolites. Therefore, the exploitation of soil microbial endophytes for the management of ARD is an important strategy.
Antibiotics in Tests for Toxicity of Snake Venom

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Preliminary experiments on the effects of snake venom on rabbits have revealed that the injection of solutions of venoms as ordinarily supplied, although under aseptic conditions, may be followed by indications not only of venom poisoning but also of bacterial action. Experimental and clinical observations on cases of snake envenomization wherein antibiotics have not been employed (to wit, in animal experiments to eliminate any bacteria contaminating the venom, and in naturally envenomated animals or humans to prevent or minimize secondary tissue bacterial contamination), cannot be accepted as reliable indicators of venom action since bacterial action may be an important factor in the symptomatology and results of the envenomization.

The Problem

The scientific literature of recent years has included several publications which appear to substantiate the above conclusion. In 1956, Parrish and others1reviewed the literature pertaining to the bacterial contaminants in the mouths and the venom glands of venomous
Analysis of Factors Delaying on Waiting Time for Medical Examination of Outpatient on a Hospital

Field: Health Professions (Health Sciences)

Background : To shorten processing time for variety of medical affairs of the patient at the outpatient clinic of a big hospital is very important to qualify medical care of the patient. Therefore, patient's waiting time for medical examination is often utilized as a strong tool to evaluate patient satisfaction with a medical care provided. We performed this study to investigate factors delaying related with waiting time for medical examination. Methods : The data were collected from June 26 to July 30, 1999. A total 275 case of medical treatment and 5,634 patients who visited outpatient clinics of a tertiary hospital were subjected to evaluate the waiting time. The data were analyzed using frequency, t-test, ANOVA, -test by SPSS Windows 7.5 program. Results : The mean patient's waiting time objectively evaluated ( min) was longer than that subjectively by patient evaluated ( min). Patient waiting time objectively evaluated was influenced by the starting time of medical examination, consultation hours, patients arriving time etc, as expected. The time discrepancy between two evaluations was influenced by several causative factors. Regarding the degree of patients accepted waiting time with the medical examination is 20 min. Conclusion : The results show that, besides the starting time of medical examination, consultation hours and patients arriving time, influence the patient's subjective evaluation of waiting time for medical examination and his satisfaction related with the service in the big hospital. In order to improve patient satisfaction related with waiting time for medical examination, it will be effective examination rather than to shorten the real processing time within the consultation room.
Timolol-Induced Bradycardia

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

* Assistant Administrative Director, Department of Anesthesia, Massachusetts Eye and Ear Infirmary; Instructor in Anaesthesia, Harvard Medical School, Boston. Department of Anesthesia, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, Massachusetts 02114. † Chief. Department of Anesthesia, Massachusetts Eye and Ear Infirmary; Assistant Clinical Professor of Anaesthesia, Harvard Medical School, Boston. Department of Anesthesia, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, Massachusetts 02114. Reprint requests to Dr. Kim. Accepted for publication December 12, 1979.