jimnoneill/paper-to-field-training huggingface dataset:
COMPARISON OF METABOLIC PROCESSES IN SMALL AND LARGE INTESTINE TISSUES IN THE ACUTE SPINAL INJURY ACCORDING TO FLUORESCENCE LIFETIME IMAGING MICROSCOPY (FLIM)

Field: Medicine (Health Sciences)

Intestinal dysfunction plays a crucial role in the developing of early and late complications in patients with spinal injury. Intestinal dysfunction can lead to metabolic imbalances like maldigestion, malabsorption, and intestinal dyskinesia. The study of metabolic processes in the tissues of the intestinal tube against the spinal cord injury can help to treat enteral and colonic insufficiency and reduce the number of surgical complications. The objective of the study is to examine the dynamics of metabolic processes in the tissues of the small and large intestines in acute spinal cord injury. Materials and Methods. The experiment was performed on laboratory animals, Wistar rats (n=22). Spinal cord injury was reproduced by complete transection of the spinal cord at the level of the Th5-Th6 vertebrae. The dynamics of cellular metabolism were assessed at different time intervals during the development of post-traumatic disease in vivo using fluorescence lifetime imaging microscopy (FLIM) based on autofluorescence in the spectral channel of the metabolic cofactor NAD(P)H. Results. The acute spinal cord injury is accompanied by changes in endogenous autofluorescence of the serous membrane tissues in the small and large intestines. A decrease in the activity of metabolic processes and their catabolic orientation are noted in the small intestine. On the contrary, metabolic processes intensify over time in the large intestine Conclusion. For the first time an in vivo experiment showed that the acute spinal injury was accompanied by a disruption of metabolic processes in the intestinal tissues. Fundamental multidirectionality was observed. Thus, a more balanced approach is necessary to combat intestinal failure in patients with acute traumatic spinal cord disease.
The generalized uncertainty principle effect in acoustic black holes

Field: Physics and Astronomy (Physical Sciences)

We obtain an effective acoustic metric with quantum corrections that are provided by a minimum length implemented by the generalized Heisenberg uncertainty principle (GUP) in the Abelian Higgs model. The effective acoustic metric now depends on the contribution of scalar and vector potentials. We also explore the Hawking radiation and entropy by considering the effective canonical acoustic black hole and find that the modified Hawking temperature leads to logarithm corrections to the entropy. Finally, we investigate the dispersion relations of the model to establish the relationships among the deviations of the group velocity, frequency and temperature due to the GUP.
Mediastinal Lobular Capillary Haemangioma in Children with Severe Airway Obstruction Symptom: A Case Report

Field: Medicine (Health Sciences)

Background: Lobular capillary haemangioma (LCH) is a polypoid form of capillary haemangioma occurring on the skin and mucosal surfaces. While LCH of the oral and nasal cavity is well-known entity, mediastinal localization is a rare case. In children, LCH is frequently benign. Case illustration: A two month age baby girl experienced recurrent inspiratory stridor since she was 42 days-old and diagnosed as laryngomalacia. Due to the widening of mediastinal area from chest x-ray, a chest CT-scan was conducted and showed a mass in the mediastinal area. A sternotomy was done and found mass filled the mediastinal space. Some parts of the mass found to depress the trachea. Mediastinal tumor resection procedure done. A definitive pathology anatomy result was a lobular capillary haemangioma. After surgery, stridor gradually improves. Summary: We reported this rare mediastinal lobular capillary haemangioma case that was initially diagnosed with laryngomalacia After removal of the tumor, the stridor gradually improved. Keywords: Lobular capillary haemangioma, pyogenic granuloma, mediastinal tumor, stridor, children
SJPYT-195:\nA Designed Nuclear Receptor Degrader That\nFunctions as a Molecular Glue Degrader of GSPT1

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

We previously reported a specific inverse agonist (SPA70)\nof the\nnuclear receptor pregnane X receptor (PXR). However, derivatization\nof SPA70 yielded only agonists and neutral antagonists, suggesting\nthat inverse agonism of PXR is difficult to achieve. Therefore, we\nsought to design proteolysis targeting chimeras (PROTACs) aimed at\ninducing PXR degradation. Conjugation of a SPA70 derivative to ligands\nof the E3 substrate receptor cereblon (CRBN) resulted in one molecule,\nSJPYT-195, that reduced PXR protein level in an optimized degradation\nassay described here. Further analysis revealed that SJPYT-195 was\na molecular glue degrader of the translation termination factor GSPT1\nand that GSPT1 degradation resulted in subsequent reduction of PXR\nprotein. GSPT1 has recently gained interest as an anticancer target,\nand our results give new insights into chemical determinants of drug-induced\nGSPT1 degradation. Additionally, we have developed assays and cell\nmodels for PXR degrader discovery that can be applied to additional\nprotein targets.
Motivational Workshops for Low Achieving High School Students in Order to Help Them Improve Their Career Maturity.

Field: Social Sciences (Social Sciences)

of a Major Applied Research Project Presented to Nova University in Partial Fulfillment of the Requirements for the Degree of Doctor of Education MOTIVATIONAL WORKSHOPS FOR LOW ACHIEVING HIGH SCHOOL STUDENTS IN ORDER TO HELP THEM IMPROVE THEIR CAREER MATURITY By Thomas R. Coleman May, 1975 Many of the students that come.to Essex County College fail. Many reasons for this failure are given. Some say that the student is not intelligent enough to meet the academic requirements of .a two year college. Others say the failure is due to the lack of preparation provided by primary and secondary schools. Still others say that the student fails because he lacks motivation. And even others say that the student does not have clear goals toward which to strive and therefore fails from lack of direction. While one can not be absolutely certain as to the reason for an individual's lack of success there is little doubt that the many community college teachers blame the primary and secondary schools for much of the student's failure in higher education. It was decided that instead of criticising the secondary schools for the lack of student success in college,that it would be better if some way could 4
2-(1H-1,2,3-Benzotriazol-1-yl)-1-(2-fluorobenzoyl)ethyl 2-chlorobenzoate

Field: Chemistry (Physical Sciences)

In the crystal structure of the title compound, C22H15ClFN3O3, the crystal packing is controlled by van der Waals forces. Weak intramolecular C—H⋯O and C—H⋯F hydrogen bonds link the molecules into chains extended along the c axis.The packing is further stabilized by van der Waals forces.
III. THE EFFECTS OF CHLORINATION ON THE RATE OF PENETRATION OF PHENOXYACETIC ACID AND BENZOIC ACID INTO LEAVES OF PHASEOLUS VULGARIS

Field: Agricultural and Biological Sciences (Life Sciences)

A comparative study has been made of the penetration into leaf disks of Phaseolus vulgaris of (a) phenoxyacetic acid and its 2-, 4-, 2,4-, 2,6-, 3-5, 2,4,5-, and 2,4,6- chloro derivatives, and (b) benzoic acid and its 2-, 2,4-, 2,5-, 2,3,6 chloro and 3,6-dichloro-2-methoxy derivatives. The methods of synthesis of each compound with 14C incorporated in the carboxyl group are described. In the series of substituted phenoxyacetic acids it was established that only for 2,4,5-T was there an appreciable loss of radioactivity from the system either in the light or darkness. In contrast, with the exception of 2,4-DCBA, 14C is lost from each member of the series of substituted benzoic acids. The level and pattern of penetration in the two series is differentially affected by chlorination. In general progressive chlorination of phenoxyacetic acid leads to an increase in the rate of penetration in both light and darkness. There are, however, exceptions; for illuminated disks the rate of entry of 2,4,5-T is exceeded by 2,4,6-T, 2,4-D, and 2,6-D whereas in the dark 2,4,5-T has by far the highest rate of penetration. Progressive chlorination of benzoic acid, however, depresses entry in both light and darkness. Possible relationships between these findings and changes in selected physical properties of each series of compounds have been examined. Between members of the series of substituted phenoxyacetic acids there is little variation in the dis sociation constant whereas for the substituted benzoic acids there is a marked lowering of the pK as the degree of chlorination increases. The rate of elution with chloroform of each compound from a buffered Silocel column gives a measure of the degree of partition into a lipid medium at a given pH. At pH 5-2 chlorination of phenoxyacetic acid results in more rapid elution whereas chlorina tion of benzoic acid causes a longer hold up. An apparatus was designed to enable measurements to be made of the rate at which a compound moves from one aqueous phase to another through a layer of lipid. Chlorination promotes the rate of transfer of phenoxyacetic acid through octanol but retards the transfer of benzoic acid. The extent to which chlorination depresses the rate of transfer of benzoic acid matches the diminution in the rate of leaf penetration. For the series of substituted phenoxyacetic acids transfer rates and penetration rates follow similar trends in the dark but in the light agree ment is less good. These findings are discussed in relation to prior studies on the rate of uptake and the metabolic fate of the individual compounds in a number of plant tissues.
Investigation of Shock Wave Impulse Influence on Solid Propellant Combustion

Field: Engineering (Physical Sciences)

The laboratory technique for test of solid propellant combustion under shock wave loading is described. The explosive generator was used for shock waves formation in propellant sample in pressure range 100 – 300 MPa. The experiments were conducted in the combustion chamber at pressure range 1 – 12 MPa. HE charge was initiated in 1–1.5 seconds after ignition of the propellant. For shock pressure in a sample less than 150 MPa, the experimental results have shown that the steady combustion regime is retained. The shock pressure increasing up to 230 MPa results in product pressure rise and consequent combustion chamber breakage. The analysis of possible causes of observed differences in regimes of burning was performed.
Biodegradable and Biocompatible Synthetic Saccharide−Peptide Hydrogels for Three-Dimensional Stem Cell Culture

Field: Materials Science (Physical Sciences)

Saccharide-peptide hydrogels have been developed in our laboratory as new synthetic extracellular matrices for regenerative medicine applications. In this work, we have expanded on our previously reported system and applied copolymerization of cysteine (Cys) and vinyl sulfone (VS)-functionalized saccharide-peptide polymers via Michael-type addition for encapsulation and 3D culture of cells. Specifically, our aims were to (1) develop a novel hydrogel platform, which could be applied for encapsulating and culturing mesenchymal stem cells (MSCs) in a 3D environment, (2) characterize the tunable properties of the hydrogel, specifically, degradation, mechanical, and gel network properties, and (3) determine the biocompatibility of the saccharide-peptide hydrogel material with MSCs. Hydrogel mechanical properties were tunable by varying the VS:Cys ratio (= 0.5, 1, or 2) as well as the pH (6, 7, or 8) of the cross-linking components. Stiffer gels were formed at VS:Cys = 1 and pH 6 or 7. Gels formed at pH 8 or with excess Cys (VS:Cys = 0.5) or VS (VS:Cys = 2) were significantly softer. Cross-linking pH and VS:Cys ratio also had an effect on the degradation behavior of the VS:Cys gels, with higher cross-linking pH resulting in an accelerated loss of mass. On the basis of environmental scanning electron microscopy (ESEM) analysis and fluorescence microscopy, all hydrogels appeared to exhibit porous gel networks. MSCs cultured in monolayer and exposed to soluble Cys or VS copolymers (0.1-5 mg/mL) did not exhibit measurable cytotoxicity. In addition, MSCs were cultured in 3D for up to 14 days in vitro without deleterious effects on cell viability. In summary, we have established and characterized a tunable 3D saccharide-peptide hybrid copolymer hydrogel platform for culturing MSCs. Future studies will focus on utilizing the hydrogel system for controlling the differentiation of MSCs.
A Grammar-Based Unsupervised Method of Mining Volitive Words

Field: Computer Science (Physical Sciences)

This paper proposes a grammar-based unsupervised method to automatically mine the Chinese volitive words, which are the important clues of intention and desiration in literal content, such as "can", "must", "rather than", etc. Besides, the paper introduces a scheme of manually tagging volitive words from large-scale Chinese blogs. And the tagged blogs are adopted as corpus to evaluate our unsupervised method in experiments. The results show a precision of 74.25% and a recall of 76.03%. Based on the above method, the paper constructs a statistical model to acquire all the volitive words with the trend of the mining, which improves the performance further.
Access to electoral rights : Ireland

Field: Social Sciences (Social Sciences)

Electoral rights for Irish citizens abroad and for foreign residents have been a topic of political debate (less so of legislative reform) for at least fifty years. There is a long-standing demand that Irish emigrants be given some parliamentary representation, in either the upper house (Seanad Éireann) or the lower house (Dáil Éireann). The only electoral rights granted to Irish citizens not ordinarily resident in the State are the right to be elected to either house of parliament and, for graduates of certain universities within the State, a vote in the election of the Senators representing those universities. Elections to the European Parliament apart, in relation to the electoral rights of non-citizens ordinarily resident in Ireland, a sharp distinction exists between local elections (where all ordinarily resident in the State, irrespective of citizenship, have both active and passive electoral rights) and elections to Dáil Éireann, in which only Irish citizens have the right to be elected and only Irish citizens, British citizens (and, potentially, citizens of other European Union member states) have the right to vote. Wide extension of electoral rights in local elections has been uncontroversial and there was little opposition to the constitutional amendment in 1984 providing for the possibility of noncitizens voting in Dáil elections. Issues concerning the extension of electoral rights generally appear to provoke relatively little public interest; extending a form of postal voting to all prisoners in the State, irrespective of their crimes or the duration of their sentences attracted little public attention.
Age And Gender Detection By Face Segmentation And Modefied CNN Algorithm

Field: Computer Science (Physical Sciences)

The fundamental purpose of the field of research known as "biometrics" is to explore the development of reliable approaches for identifying individuals using their observable traits. Examples of biometric identification include both physical and mental traits of an individual. As a kind of physical identification, fingerprints and facial features may be compared and analyzed. Human gait has been researched because it has the potential to be used as a behavioral identifier in computer visionUsing a Convolutional Neural Network (CNN) and a Support Vector Machine, the capacity to estimate a person's gender based on their stride was explored and investigated (SVM). Throughout our examination of CNN's potential uses for gait-based gender identification, we will strive for both a high degree of accuracy and a cheap computational cost. We analyzed and experimented with a variety of CNN architectures and hyperparameters in this setting.
A study on the stability of Shiweigukang oral solution

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective To investigate the stability and expiration date of Shiweigukang oral solution. Methods Influencing factors test, acceleration test, and long-term test were conducted to investigate properities, identification, filling volume, PH value, relative density, and microbial limits.Results EverT examination index on influencing factors test, acceleration test, and long-term test met the standards. This oral solution was blown in color and slightly bitter, and had little sediment. Shiweigukang showed the spots with the same color as those of epimedium, white paeony root, and malaytea scurfpea fruit on the color spectrum. The filling volume was not less than 10 ml/bottle; the relative density was not smaller than 1.02; PH value was 3.5 to 5.5; bacterial count was less than 10/ml; and mould and saccharomycetes count was less 10/ml. No E. Coliand mites were found. Conclusions Shiweigukang oral solution has good stability and an expiration date of two years.

Key words:
Shiweigukang oral soluation ; Stability ; Expiration date
Anxiety and Pain in Patients Undergoing Pipelle Endometrial Biopsy: A Prospective Study [11F]

Field: Medicine (Health Sciences)

INTRODUCTION: Pipelle biopsy is a minimally invasive endometrial sampling procedure, important for early diagnosis of endometrial pathology and treatment planning. While generally well tolerated, some women experience considerable pain. The prospective study reported here provides a first critical test of the hypothesis that heightened anxiety may contribute to the risk of severe pain in women undergoing Pipelle biopsy. METHODS: Pain and anxiety levels immediately prior to, during, and after the Pipelle biopsy were assessed (0-10 numeric rating) in a sample (n=113) of consecutively recruited women undergoing outpatient Pipelle biopsies in a tertiary care facility. Personal and clinical data were extracted from medical records and from surveys administered to providers. Multivariable logistic regression models and generalized estimating equations examined associations between severe (≥7) pain and anxiety prior to, during, and after the biopsy. RESULTS: Severe pain was reported by 9%, 43%, and 13% of participants prior to, during and after the procedure (respectively), while severe anxiety was reported by 30%, 38% and 12%. Pain was significantly associated with anxiety levels at all times assessed. Adjusting for covariates (e.g., age, BMI, biopsy indication), the odds of severe pain prior to, during, and after biopsy were 5.9, 2.3, and 11.0 times higher (respectively) for patients with severe anxiety prior to the procedure. CONCLUSION: The strong relationships between anxiety prior to Pipelle biopsy and patients’ experiences of severe pain associated with the procedure suggest that interventions aimed at reducing anxiety might substantially improve the patient experience of this widely-used procedure for endometrial biopsy.
Strengthening Children’s Religious And Moral Values In Shamil And Dodo Cartoon Film

Field: Arts and Humanities (Social Sciences)

The current era of education for children is experiencing a moral crisis in the aspects of religious and moral development. Religious and moral values ​​of children will be formed through interaction and environmental responses to an active five-sensory performance system. Cartoon films are a strategy for developing children's creativity. By presenting imaginative, interactive, and fun story events through the behavior and attitudes of the characters in cartoon films. The cartoon film Syamil and Dodo became a cartoon film by NCR Production which was made to educate children because it was rich in Islamic educational values ​​and religious and moral values ​​which were suitable to stimulate early childhood. The problem in this research is: "How is the strengthening of religious and moral values ​​in the cartoon film Syamil and Dodo?". The research analyzes the strengthening of religious and moral values ​​in the cartoon film Syamil and Dodo. This type of research is library or Library Research using the cartoon film Syamil and Dodo as the primary data source in this study. Meanwhile, secondary data were obtained from journals, books, and previous thesis. The data collection technique in this research is documentation by observing footage from the cartoon film Syamil and Dodo. Based on the research conducted by the author, the cartoon film Syamil and Dodo is a cartoon film suitable for watching early childhood, the film contains religious and moral educational values ​​for children aged 4-6 years. Strengthening the Syamil and Dodo cartoons can be a medium to reflect and actualize how to properly instill religious and moral values ​​for children in the scope of family and school education.
Evaluation of the effects of run off water on the Founkama plain in the Urban commune of Faranah, Republic of Guinea

Field: Environmental Science (Physical Sciences)

This research aims to assess the effects of runoff water on flood basins and structures. To achieve this, we identified the decomposable and non-decomposable materials that ran off the flood basins and into the canals; the effects of runoff on the flood basins; Quantify the volumes of soil transported by runoff on the north and south sides of the said plain; The research work took place from January 2 to October 31, 2014 inclusive. The results obtained are as follows: The area occupied by non-decomposable materials in sample per m2 is: 106.74; the average weight of the samples is 4.6 kg; the height of earth transported in layers in the submersion basins in cm is: the North side 60, the South side 47.5 and in the central canal 58.6; the volume of earth transported in the canals in m3 is: in the North belt canal 224.4 in the South belt canal 89.25 and in the central canal 599.4; the influx of earth deposits by runoff water in the belt canals in cm is: South 58.188 and North 45.278.
Conglomerate Horizons in South-Central Rajasthan and their Significance on Proterozoic Stratigraphy and Tectonics of the Aravalli and Delhi Fold Belts

Field: Earth and Planetary Sciences (Physical Sciences)

Abstract The Proterozoic sequences of South-Central Rajasthan are contained in the Lower to Middle Proterozoic Aravalli and Middle to Upper Proterozoic Delhi fold belts. The stratigraphic relations within these fold belts as well as the basement-cover relations are beset with several problems. The conglomerate horizons have been studied to address some of these problems. Based on the conglomerate horizons, representing erosional unconformities, the Aravalli Supergroup has been sub-divided into three groups and the Delhi Supergroup of the South Delhi fold belt into two groups with constituent formations. These horizons are also useful in identifying three stages of basin evolution for the Aravalli fold belt. The Middle Aravalli Conglomerate is the most prominent representing mid-Aravalli hiatus, and corresponding to the Debari Transgressive Stage which followed the Delwara Rifting Stage in the Lower Aravalli in a system of ensialic distensional tectonics where triple-junctions and pull-apart basins are formed. The Upper Aravalli has been the Jharol Ocean Opening Stage, the oceanic/transitional crust having been consumed at a median ultramafic suture line during the formation of the Aravalli fold belt. The South Delhi fold belt has also multi-stage development history with the Barr Conglomerate representing the base of the youngest Delhi sequence.