jimnoneill/paper-to-field-training huggingface dataset:
Pleiotropic effects of enhancing vacuolar K/H exchange in tomato

Field: Agricultural and Biological Sciences (Life Sciences)

Cation antiporters of the NHX family are widely regarded as determinants of salt tolerance due to their capacity to drive sodium (Na) and sequester it into vacuoles. Recent work shows, however, that NHX transporters are primarily involved in vacuolar potassium (K) storage. Over‐expression of the K/H antiporter AtNHX1 in tomato increases K accumulation into vacuoles and plant sensitivity to K deprivation. Here we show that the appearance of early leaf symptoms of K deficiency was associated with higher concentration of polyamines. Transgenic roots exhibited a greater sensitivity than shoots to K deprivation with changes in the composition of the free amino acids pool, total sugars and organic acids. Concentrations of amides (glutamine), amino acids (arginine) and sugars significantly increased in root, together with a reduction in malate and succinate concentrations. The concentration of pyruvate and the activity of pyruvate kinase were greater in the transgenic roots before K withdrawal although both parameters were depressed by K deprivation and approached wild‐type levels. In the longer term, the over‐expression of the NHX1 antiporter affected root growth and biomass partitioning (shoot/root ratio). Greater ethylene release produced longer stem internodes and leaf curling in the transgenic line. Our data show that enhanced sequestration of K by the NHX antiporter in the vacuoles altered cellular K homeostasis and had deeper physiological consequences than expected. Early metabolic changes lead later on to profound morphological and physiological adjustments resulting eventually in the loss of nutrient use efficiency.
Bat Optimized Watershed based Segmentation of Lamina Cribrosa

Field: Computer Science (Physical Sciences)

The segmentation of Lamina Cribrosa(LC) is a challenging task to detect the glaucomatous damage. In this paper a new method of segmenting the LC using bat optimized Watershed segmentation is done. By using wavelet transform LC structures are decomposed. Then, the decomposed image is optimized using Bat algorithm and by applying histogram equalization the optimized image is normalized. Watershed algorithm is used to segment the Lamina Cribrosa from its outer layer. Using some parameters like PSNR, MSE, F-Measure, rand index, sensitivity, specificity, SSIM and accuracy, the performance of the proposed system is calculated. The results show that the proposed method provides higher accuracy of 99.29%.
Development of Proportional Counters Using Photosensitive Gases and Liquids

Field: Physics and Astronomy (Physical Sciences)

An introduction to the history and to the principle of operation of wire chambers using photosensitive gases and liquids is presented. Their use as light sensors coupled to Gas Scintillation Proportional Counters and BaF2, as well as their use in Cherenkov Ring Imaging, is discussed in some detail.
Investigation of Tissue Inhibitor of Metalloproteinases 1 in Plasma from Colorectal Cancer Patients and Blood Donors by Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

Field: Medicine (Health Sciences)

Early detection of colorectal cancer (CRC) improves patient survival. Plasma tissue inhibitor of metalloproteinases 1 (TIMP-1) measurements by enzyme-linked immunosorbent assay (ELISA) have been suggested as a new method for the early detection of CRC. To further investigate the nature of TIMP-1 in plasma, surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI TOF MS) was used. TIMP-1 measurements of plasma from 16 healthy donors and 14 CRC patients were performed using TIMP-1 monoclonal antibody in SELDI TOF MS and ELISA. SELDI TOF MS applying an antibody to TIMP-1 revealed that human plasma TIMP-1 has a mass of 25.1 kDa and exhibits several isoforms. Both methods showed increased plasma TIMP-1 values for cancer patients as compared to healthy individuals. The p values for the separation of the groups were 0.0019 for ELISA and <0.0001 for SELDI TOF MS. CRC did not fundamentally affect the appearance of TIMP-1 as evaluated by SELDI TOF MS.
Examination of wheat kernels for the presence of Fusarium damage and mycotoxins using near-infrared hyperspectral imaging

Field: Agricultural and Biological Sciences (Life Sciences)

The agriculture industry experiences severe economic losses each year when wheat crops become infected with Fusarium and the mycotoxin Deoxynivalenol (DON). This research investigated the feasibility of using near infrared hyperspectral imaging to detect Fusarium damage and DON in Canadian Western Red Spring wheat. Four samples were selected from each grain grade resulting in 16 samples and 240 hyperspectral data cubes. The data cubes were calibrated to the system, the consistent spectra was found and then a 1- nearest neighbour classifier was generated. Grade percentages were computed and used to generate two 3- nearest neighbour classifiers, one for identifying Fusarium damage and the other for identifying DON content. The Fusarium damage classifier had an accuracy of 85% and the DON content classifier had an accuracy of 80%. While a single sample image classification will not replace manual testing, the use of multiple samples from one harvest could reduce manual inspections.
Big Data: Evaluating business value and firm performance

Field: Business, Management and Accounting (Social Sciences)

This report is an output of a research project co-financed by Grenoble Ecole de Management and Auvergne-Rhône-Alpes French region. This study was conducted with the aim of understanding how Information Technology (IT) provides new opportunities to firms, specifically focusing on the role of Big Data in creating value for the companies. Gartner defines Big Data as "high volume, velocity and/or variety information assets that demand cost-effective, innovative forms of information processing that enable enhanced insight, decision making, and process automation".
KEGIATAN PELAKSANAAN PEMELIHARAAN TANAM POHON KAMPUNG BUNGA WARNA WARNI DI DESA SUKALAKSANA RW.01 RT.016

Field: Agricultural and Biological Sciences (Life Sciences)

Community service activities in the implementation of the maintenance of planting colorful flower village trees in Sukalaksana Village RW.01 RT.016 as a form of environmental conservation that needs to be cultivated, this activity is carried out with the involvement of the Sukalaksana Village community, Youth Organizations, and a team of KKM Students Group 11 UNBAJA 2021. The Maintenance of Planting Colorful Flower Village Trees in Sukalaksana Village RW.01 RT.016 is expected to be able to make the first tap of public awareness to have concern for the environment, especially in this flower village or also called by its original name Kaningan village. This activity not only aims to realize reforestation in Sukalaksana village, but it is also one of the work programs of the 2021 Unbaja Group 11 KKM team, In this community service program method, the team uses an activity method with several stages, namely the Planting Planning stage, Planting Preparation, Determination of Candidate Locations, Need for Number of Seeds, Planting Design, namely the preparation and selection of plant types. Next is tree planting, namely the stage of the tree planting process, from this community service the results obtained are increasing public awareness to have a concern for the environment and nature conservation, especially in this flower village in Sukalaksana Village.
Review: Architecture and the Historical Imagination: Eugène-Emmanuel Viollet-le-Duc, 1814–1879, by Martin Bressani

Field: Arts and Humanities (Social Sciences)

Book Review| June 01 2017 Review: Architecture and the Historical Imagination: Eugène-Emmanuel Viollet-le-Duc, 1814–1879, by Martin Bressani Martin BressaniArchitecture and the Historical Imagination: Eugène-Emmanuel Viollet-le-Duc, 1814–1879Farnham, England: Ashgate, 2014, 624 pp., 86 color and 64 b/w illus. $114.95, ISBN 9780754633402 Sean Weiss Sean Weiss City College of New York Search for other works by this author on: This Site PubMed Google Scholar Journal of the Society of Architectural Historians (2017) 76 (2): 245–248. https://doi.org/10.1525/jsah.2017.76.2.245 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Sean Weiss; Review: Architecture and the Historical Imagination: Eugène-Emmanuel Viollet-le-Duc, 1814–1879, by Martin Bressani. Journal of the Society of Architectural Historians 1 June 2017; 76 (2): 245–248. doi: https://doi.org/10.1525/jsah.2017.76.2.245 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentJournal of the Society of Architectural Historians Search When the French architect, theorist, and ardent medievalist Eugène-Emmanuel Viollet-le-Duc taught at the Parisian École des Beaux-Arts, he was met by the sneers of students, a reception that ultimately led him to resign after his seventh lecture on 18 March 1864. Scarcely four months earlier, he had been appointed to the newly minted chair of art history and aesthetics at France's stronghold of academic tradition. He had already published most of the volumes of his influential Dictionnaire raisonné de l'architecture française du XIe au XVIe siècle (Dictionary of French Architecture from the Eleventh to the Sixteen Century) and Entretiens sur l'architecture (Lectures on Architecture).1 He was also overseeing the restoration of a number of significant medieval monuments under the auspices of the French government's Commission des Monuments Historiques. At the height of his career, he had developed the modern conception of restoration and... You do not currently have access to this content.
Infant Sleep Position Placing infants to sleep on their backs reduces the risk of

Field: Health Professions (Health Sciences)

Sudden Infant Death Syndrome (SIDS) – one of the leading causes of death to infants. 46 In Oregon, SIDS is the number one cause of death to older infants (between 28 days and up to 1 year), accounting for nearly 30 percent of all deaths in this age group during 2002-2004. 47 The American Academy of Pediatrics recommends that healthy infants younger than 6 months of age be placed to sleep on their back. 48 • In 2004, Oregon mothers were significantly more likely than other U.S. 49 mothers to place their infants to sleep on their backs – 74.7 versus 65.1 percent, respectively. Furthermore, Oregon achieved the Healthy People 2010 target of having at least 70 percent of infants put to sleep on their backs. • Although Oregon mothers were more likely to place their infants to sleep on their backs than any other position, more than a quarter (25.3 percent) of Oregon infants were put to sleep in the higher risk
Reference‐free discovery of nuclear SNPs permits accurate, sensitive identification of Carya (hickory) species and hybrids

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Premise DNA‐based species identification is critical when morphological identification is restricted, but DNA‐based identification pipelines typically rely on the ability to compare homologous sequence data across species. Because many clades lack robust genomic resources, we present here a bioinformatics pipeline capable of generating genome‐wide single‐nucleotide polymorphism (SNP) data while circumventing the need for any reference genome or annotation data. Methods Using the SISRS bioinformatics pipeline, we generated de novo ortholog data for the genus Carya , isolating sites where genetic variation was restricted to a single Carya species (i.e., species‐informative SNPs). We leveraged these SNPs to identify both full‐species and hybrid Carya specimens, even at very low sequencing depths. Results We identified between 46,000 and 476,000 species‐identifying SNPs for each of eight diploid Carya species, and all species identifications were concordant with the species of record. For all putative F 1 hybrid specimens, both parental species were correctly identified in all cases, and more punctate patterns of introgression were detectable in more cryptic crosses. Discussion Bioinformatics pipelines that use only short‐read sequencing data provide vital new tools enabling rapid expansion of DNA identification assays for model and non‐model clades alike.
Autosensitivity Diseases

Field: Medicine (Health Sciences)

A NUMBER of clinical syndromes are now recognized in which there is immunologic hyperactivity and tissue damage without an obvious exogenous cause for the damage. The concept that immunologic factors are themselves the cause of the damage has been a natural development. Autoantibodies have been found in some of these conditions, and the term "autoimmune diseases" has been used to refer to the disorders. Many prefer the term "autosensitive" or "autoallergic," however, for two reasons: immunity in the classic sense is not involved; and the word "autosensitive" or "autoallergic" carries the important qualification that autoantibodies may represent only a liability . . .
A Prospective Randomized Trial Comparing Percutaneous Local Ablative Therapy and Partial Hepatectomy for Small Hepatocellular Carcinoma

Field: Medicine (Health Sciences)

OBJECTIVE: To compare the results of percutaneous local ablative therapy (PLAT) with surgical resection in the treatment of solitary and small hepatocellular carcinoma (HCC). SUMMARY BACKGROUND DATA: PLAT is effective in small HCC. Whether it is as effective as surgical resection in the long-term survivals remains unknown. METHODS: We conducted a prospective randomized trial on 180 patients with a solitary HCC ≦5 cm to receive either PLAT or surgical resection. The patients were regularly followed up after treatment with physical examination, blood, and radiologic tests. RESULTS: Of the 90 patients who were randomized to PLAT, only 71 received PLAT because 19 withdrew their consent. Of the 90 patients who were randomized to surgical resection, a single Couinaud liver segment resection was carried out in 69 patients, 2 segments in 16 patients, and 3 or more segments in 3 patients. Ethanol injection was given during open surgery in 2 patients. Only 1 patient died after surgical resection within the same hospital admission. Posttreatment complications were more often and severe after surgery than PLAT. The 1-, 2-, 3-, and 4-year overall survival rates after PLAT and surgery were 95.8%, 82.1%, 71.4%, 67.9% and 93.3%, 82.3%, 73.4%, 64.0%, respectively. The corresponding disease-free survival rates were 85.9%, 69.3%, 64.1%, 46.4% and 86.6%, 76.8%, 69%, 51.6%, respectively. Statistically, there was no difference between these 2 treatments. CONCLUSION: PLAT was as effective as surgical resection in the treatment of solitary and small HCC. PLAT had the advantage over surgical resection in being less invasive.
Neuroprotective Effect of Buyang Huanwu Decoction on Rat Ischemic/Reperfusion Brain Damage by Promoting Migration of Neural Precursor Cells

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Buyang Huanwu Decoction (BYHWD) is a classic formula widely used for treating stroke-induced disability, the highest morbidity of neurological disorders in China. However, the mechanism of its neuroprotection has not been fully clarified. Previous reports indicated that BYHWD may promote growth and differentiation of neural precursor cells (NPCs). The present study focused on the effects of BYHWD on migration of NPCs in rats with middle cerebral artery occlusion (MCAO). Rats were treated with different doses of BYHWD (12 and 24 grams/kg) from day 1 to day 21 after model building. BYHWD could increase the survival rate and decrease neurological scores and infarct volume as compared with the vehicle-treated MCAO rats. Moreover, BYHWD treatment significantly increased 5-bromo-2-deoxyuridine (BrdU)-positive cells in the subventricular zone (SVZ), subgranular zone (SGZ), and corpus striatum (CS) of the infarct brain. Interestingly, BYHWD could markedly enhance BrdU + /doublecortin + cells not only in the SVZ and SGZ but also in CS, by up-regulating the protein expression of migration activators, including stromal cell derived factor-1, CXC chemokine receptor 4, vascular endothelial growth factor, Reelin, and brain-derived neurotrophic factor in the ipsilateral infarct area after MCAO. In addition, BYHWD treatment was able to promote the neuronal differentiation, which was closely related to the migratory process of NPCs in MCAO rats. These findings offer evidence for the first time that BYHWD may exert its neuroprotective effects partially by promotion of NPCs migration to ischemic brain areas.
Highly sensitive photodetection using a microwave-coupled BaPb0.7Bi0.3O3 Josephson junction array

Field: Physics and Astronomy (Physical Sciences)

The BaPb0.7Bi0.3O3 sputtered film possesses tunnel Josephson junctions at boundary layers [boundary Josephson junction (BJJ)] normal to the film plane in a homogeneous junction array. The film has high efficiency for optical irradiation of the junctions because of the high optical transparency. The letter presents the optical effect on the current-voltage characteristics for this Josephson junction array locked to a microwave field. The microwave-induced hysteresis loop caused by voltage locking among junctions in a microwave field is highly sensitive to optical illumination with as low an incident power as a few nanowatts. This probably can be exploited in a future, highly sensitive photodetector.
Kinetics and Thermodynamics of Limonene Ozonolysis

Field: Chemistry (Physical Sciences)

Using density functional methods, the initial reaction steps of limonene ozonolysis have been investigated with a focus on primary ozonide formation and its decomposition to Criegee intermediates and carbonyl compounds. The ozonide formation is highly exothermic, and the decomposition channels have similar free energies of activation, ΔG(‡), indicating that there is no primary pathway for ozonide decomposition. Assuming that ozonide formation is the rate limiting step, the theoretical rate coefficient, k = 1.6 × 10(-16) molecule(-1) cm(3) s(-1), evaluated at the CCSD(T)/6-31G(d,p)//BHandHLYP/cc-pvdz level and 298.15 K for d-limonene is in good agreement with the experimental value, k(exp) = 3.3 × 10(-16) molecule(-1) cm(3) s(-1). The theoretical Arrhenius expression is also in good agreement with experimental results.
Mucin 4 and matrix metalloproteinase 7 as novel salivary biomarkers for periodontitis

Field: Dentistry (Health Sciences)

Abstract Aim Periodontitis is a chronic inflammatory disease, characterized by irreversible destruction of tooth‐supporting tissue including alveolar bone. We recently reported mucin 4 ( MUC 4) and matrix metalloproteinase 7 ( MMP 7) as highly associated with periodontitis in gingival tissue biopsies. The aim of this study was to further investigate the levels of MUC 4 and MMP 7 in saliva and gingival crevicular fluid ( GCF ) samples of patients with periodontitis. Materials and Methods Saliva and GCF samples were collected from periodontitis patients and healthy controls. The levels of MUC 4, MMP 7, and total protein concentrations were analysed using ELISA or Bradford assay. Results MUC 4 levels were significantly lower in saliva and GCF from periodontitis patients relative to healthy controls. MMP 7 levels were significantly higher in saliva and GCF from periodontitis patients. Multivariate analysis revealed that MUC 4 was significantly associated with periodontitis after adjusting for age and smoking habits and, moreover, that the combination of MUC 4 and MMP 7 accurately discriminated periodontitis from healthy controls. Conclusions MUC 4 and MMP 7 may be utilized as possible novel biomarkers for periodontitis.
Tick Bite Prophylaxis: Results From a 2012 Survey of Healthcare Providers

Field: Health Professions (Health Sciences)

Summary In a recent national survey, over 30% of healthcare providers ( HCP s) reported prescribing tick bite prophylaxis in the previous year. To clarify provider practices, we surveyed HCP s to determine how frequently and for what reasons they prescribed tick bite prophylaxis. We included four questions regarding tick bite prophylaxis in the DocStyles 2012 survey, a computer‐administered questionnaire of 2205 US primary care physicians, paediatricians and nurse practitioners. Responses in 14 states with high Lyme disease incidence (high LDI ) were compared with responses from other states (low LDI ). Overall, 56.4% of 1485 providers reported prescribing tick bite prophylaxis at least once in the previous year, including 73.9% of HCP s in high LDI and 48.2% in low LDI states. The reasons given were ‘to prevent Lyme disease’ (76.9%), ‘patients request it’ (40.4%) and ‘to prevent other tickborne diseases’ (29.4%). Among HCP s who provided prophylaxis, 45.2% did so despite feeling that it was not indicated. Given a hypothetical scenario involving a patient with an attached tick, 38.1% of HCP s from high LDI states and 15.1% from low LDI states would prescribe a single dose of doxycycline; 19.0% from high LDI states and 27.5% from low LDI states would prescribe a full course of doxycycline. HCPs prescribe tick bite prophylaxis frequently in areas where Lyme disease is rare and for tickborne diseases for which it has not been shown effective. HCPs may be unaware of current tick bite prophylaxis guidelines or find them difficult to implement. More information is needed regarding the efficacy of tick bite prophylaxis for diseases other than Lyme disease.
Elastic Modulus Prediction of Asphalt Concrete

Field: Engineering (Physical Sciences)

The distresses of asphalt pavement, which include fatigue, rutting, and low temperature cracking, are related to the elastic modulus of asphalt concrete (AC). In addition, the elastic modulus of AC is a design variable for asphalt pavement structural design when elastic-layer system theory is employed. However, in the most commonly used AC design methods (the Marshall, Hveem, and Superpave methods), the elastic modulus is not used as a control variable. Therefore, these design methods do not ensure that the desired elastic modulus of AC will be obtained. In this paper, AC is treated as a two-phase composite with aggregates dispersed in the asphalt matrix. Based on this treatment, a two-layer built-in micromechanical model of AC is developed by embedding an asphalt-coated circular aggregate into an equivalent AC medium. Using this model, an equation predicting the elastic modulus of AC is derived. The elastic modulus of AC predicted by the present model is compared with the Hashin and Shtrikman theoretical bounds and the Heukelom and Klomp equation. Using these comparisons, the proposed model is shown to be reasonable and applicable for predicting the elastic modulus of AC. Thus, the existing mix design approaches can be improved by using the modulus prediction model presented in this paper.