jimnoneill/paper-to-field-training huggingface dataset:
Effects of Performance Appraisal on Employee Productivity in Federal Ministry of Education Headquarters Abuja Nigeria

Field: Business, Management and Accounting (Social Sciences)

The study examined the effects of Performance Appraisal on Employee Productivity in Federal Ministry of Education Headquarters Abuja. The study used survey research design. The population of the study consists of 1797 employees of Federal Ministry of Education Headquarters Abuja. The sample size of the study was 400 respondents and was determined using Taro Yamane formula. Data for the study was collected using structured questionnaire and analyzed using descriptive and OLS analysis. Results from the findings revealed that the coefficients of appraisal performance and employee feedback had positive and significant effect on employee productivity for the period under study. The coefficients of employee training and employee compensation had positive but insignificant effect on employee productivity for the period under study. The coefficient of multiple determination R2 value of 0.687 percent implied that 68 percent total variation in employee productivity was explained by performance appraisal, employee feedback, employee training and employee compensation. The study recommends that multiple appraisal method should be introduced to further encourage objectivity and eliminate biasedness in the appraisal of workers in the Ministry.
Sonographic findings in acute uterine inversion

Field: Medicine (Health Sciences)

We present a case of acute uterine inversion in the third stage of labor in which critical management decisions were facilitated by ultrasound imaging in the operating room. Identification of the ovary and adnexa pulled into the indentation of the inversion allowed the successful diagnosis and guidance for uterine replacement. © 2013 Wiley Periodicals, Inc. J Clin Ultrasound 41:453–456, 2013
P-glycoprotein attenuates DNA repair activity in multidrug-resistant cells by acting through the Cbp-Csk-Src cascade

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Recent studies have demonstrated that P-glycoprotein (P-gp) expression impairs DNA interstrand cross-linking agent-induced DNA repair efficiency in multidrug-resistant (MDR) cells. To date, the detailed molecular mechanisms underlying how P-gp interferes with Src activation and subsequent DNA repair activity remain unclear. In this study, we determined that the C-terminal Src kinase-binding protein (Cbp) signaling pathway involved in the negative control of Src activation is enhanced in MDR cells. We also demonstrated that cells that ectopically express P-gp exhibit reduced activation of DNA damage response regulators, such as ATM, Chk2, Braca1 and Nbs1 and hence attenuated DNA double-strand break repair capacity and become more susceptible than vector control cells to DNA interstrand cross-linking (ICL) agents. Moreover, we demonstrated that P-gp can not only interact with Cbp and Src but also enhance the formation of inhibitory C-terminal Src kinase (Csk)-Cbp complexes that reduce phosphorylation of the Src activation residue Y416 and increase phosphorylation of the Src negative regulatory residue Y527. Notably, suppression of Cbp expression in MDR cells restores cisplatin-induced Src activation, improves DNA repair capacity, and increases resistance to ICL agents. Ectopic expression of Cbp attenuates cisplatin-induced Src activation and increases the susceptibility of cells to ICL agents. Together, the current results indicate that P-gp inhibits DNA repair activity by modulating Src activation via Cbp-Csk-Src cascade. These results suggest that DNA ICL agents are likely to have therapeutic potential against MDR cells with P-gp-overexpression.
Efektivitas Pembelajaran Daring Masa Pandemi Covid-19 Mata Kuliah Evaluasi Pembelajaran Prodi Pendidikan Bahasa Dan Sastra Jawa FBS UNNES

Field: Social Sciences (Social Sciences)

Education is one of the aspects affected by the Covid-19 pandemic. The online learning that has been taken since the outbreak began in March 2020 has an impact on the effectiveness of the learning outcomes themselves. This research is a qualitative research that aims to obtain a description of online learning for the Learning Evaluation course at the Javanese Language and Literature Education Study Program, Faculty of Language and Arts, Universitas Negeri Semarang, even semester 2020/2021. Online learning at Unnes uses the Elena system to support optimizing lecture outcomes. The technique of collecting data in this study used a questionnaire technique with 92 respondents in the sixth semester of the Java Language and Literature Education Study Program who took the Learning Evaluation course. The data analysis technique uses the Miles & Huberman (1994) technique which consists of three stages, namely data reduction, data display, and drawing conclusions and reflections. The results of this study indicate that online learning has been effective in achieving the learning objectives of the course, but it needs to be improved so that it is more structured in providing online material. The results of this study are used as guidelines for improving online learning, especially in the Learning Evaluation course in the coming semester and online learning in all courses in general.
Epidemiological Survey of Porcine Circovirus Type 2 (PCV2) in Large-Scale Pig Farms in Hubei Province and Comprehensive Evaluation of Commercial Vaccine Efficacy

Field: Veterinary (Health Sciences)

Background: Porcine circovirus type 2 (PCV2) is the primary pathogen responsible for postweaning multisystemic wasting syndrome (PMWS) and related diseases, leading to significant economic losses in the global pig industry. Methods: This study conducted a thorough epidemiological survey between 2022 and 2024, gathering 6600 samples from 24 large-scale pig farms in Hubei Province. On the basis of these findings, the immune response and economic benefits of two representative commercial PCV2 subunit vaccines, recombinant baculovirus CP08 and Ingelvac CircoFLEX®, were assessed in a modern fattening farm in Xiangyang city. Results: The results indicated no detection of viral antigens in sows; however, weaned piglets and fattening pigs presented high positivity rates, with 8-week-old nursery pigs identified as the peak period for infection. Both vaccines significantly improved average weight gain and reduced antigen positivity, with Ingelvac CircoFLEX® demonstrating superior viral control and economic returns. Conclusions: This study offers valuable scientific and practical guidance for PCV2 control strategies and vaccine selection in Hubei and comparable regions.
Apoptosis and expression of stress protein (ORP150, HO1) during development of ischaemic osteonecrosis in the rat

Field: Medicine (Health Sciences)

Using in situ hybridisation and the terminal deoxynucleotidyl transferase-mediated biotin-dUTP nick end-labelling (TUNEL) reaction in rats with osteonecrosis of the femoral head we have studied the effect of ischaemia on the gene expression of the stress proteins oxygen-regulated protein 150 (ORP150) and haemoxygenase 1 (HO1) and the death mechanism of the cells involved in osteonecrosis. Both ORP150 and HO1 have been reported to have important roles in the successful adaptation to oxygen deprivation. ORP150 and HO1 mRNA expression was induced by ischaemia in osteoblasts and osteocytes. In proliferative chondrocytes, these signals were detected constitutively. During the development of ischaemic osteonecrosis, the mechanism of cell death was apoptosis as indicated by DNA fragmentation and the presence of apoptotic bodies in osteocytes, chondrocytes and bone-marrow cells. After the initial ischaemic event, expression of ORP150 and HO1 mRNA, the TUNEL-positive reaction and empty lacunae were found sequentially. These findings were exclusive and may be considered to be markers for each stage in the development of osteonecrosis.
Knowledge on obstetric danger signs among antenatal mothers attending a tertiary level hospital, Nepal

Field: Health Professions (Health Sciences)

Background & Objectives: All pregnant women are at risk and can face problems at any time during or following pregnancy and childbirth which can cause death of mothers. Knowledge of key danger signs is essential for motivating women to seek skilled attendance at birth and also to seek referral in case of complications which definitely improves health of the mother and newborns. This study aimed to assess pregnant womens’ knowledge about obstetric danger signs and its associated factors.Materials & Methods: Quantitative approach with a facility based cross-sectional study was conducted among pregnant mothers attending Anti Natal Clinic of Dhulikhel hospital, Nepal. Data was collected from 1st June to 25th June 2017. Sampling technique was non probability, purposive sampling technique. A standardized tool was adopted. Face to face interview technique was used. Data had been processed by SPSS 20 version then analyzed using descriptive as well as inferential statistic.Results: Two third of the respondents (66.0%) had adequate knowledge on obstetric danger signs, while 21.0% of respondents had inadequate knowledge and few respondents (13.0%) had moderate knowledge on that. Age, educational status and gravida were not significantly associated with knowledge on obstetric danger signs but occupation and trimester of pregnancy were found to be associated with the same.Conclusion: A significant proportion of pregnant women do not have adequate knowledge on obstetric danger signs. Therefore, the quality of health information about obstetric danger signs during ANC follow up is to be improved.
Determiner-Established Deixis to Communicative Artifacts in Pedagogical Text

Field: Computer Science (Physical Sciences)

Pedagogical materials frequently contain deixis to communicative artifacts such as textual structures (e.g., sections and lists), discourse entities, and illustrations. By relating such artifacts to the prose, deixis plays an essential role in structuring the flow of information in informative writing. However, existing language technologies have largely overlooked this mechanism. We examine properties of deixis to communicative artifacts using a corpus rich in determiner-established instances of the phenomenon (e.g., “this section”, “these equations”, “those reasons”) from Wikibooks, a collection of learning texts. We use this corpus in combination with WordNet to determine a set of word senses that are characteristic of the phenomenon, showing its diversity and validating intuitions about its qualities. The results motivate further research to extract the connections encoded by such deixis, with the goals of enhancing tools to present pedagogical e-texts to readers and, more broadly, improving language technologies that rely on deictic phenomena.
What Do We Learn from Gene Deletion and Overexpression for Adrenal Function?

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The adrenal gland affects many of the body’s physiological processes of endocrine, metabolic, and immunologic nature. It is crucial in the adaptation to stress as the central effector organ of both the stress systems of the body. Alterations in adrenal function may thus result in severe consequences for the integrity of the organism, and adrenal function is tightly regulated by a complex network of regulatory mechanisms. Endogenous and exogenous genetic alterations now allow a functional dissection and analysis of single components of both classical and newly discovered regulatory mechanisms for evaluating their physiological importance in an otherwise intact organism.
Design of a Carbon Monoxide Gas Measurement Tool Using Microcontroller-Based MQ-7 Gas Sensor in Households

Field: Engineering (Physical Sciences)

The increasing presence of carbon monoxide in residential environments poses a serious health risk due to its colorless, odorless, and tasteless nature. This study aims to develop and evaluate a carbon monoxide detection system using the MQ-7 sensor integrated with an Arduino microcontroller. The research employs an experimental design approach with a sequential development model, including system analysis, design, coding, and testing phases. The system is designed to detect carbon monoxide levels and provide early warnings using visual and auditory indicators. Testing results indicate that the system successfully detects varying concentrations of carbon monoxide with satisfactory accuracy and provides timely alerts. This study contributes significantly to household safety by offering a simple, effective, and affordable solution for carbon monoxide detection, thereby enhancing preventive measures against potential carbon monoxide exposure.
The Headgroup Evolution of Cationic Lipids for Gene Delivery

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Cationic lipids are one of the most widely used nonviral vectors for gene delivery and are especially attractive because they can be easily synthesized and extensively characterized. Additionally, they can best facilitate the elucidation of structure-activity relationships by modifying each of their constituent domains. The polar hydrophilic headgroups enable the condensation of nucleic acids by electrostatic interactions with the negatively charged phosphate groups of the genes, and further govern transfection efficiency. The headgroups of cationic lipids play a crucial role for gene delivery; they can be quaternary ammoniums, amines, aminoacids or peptides, guanidiniums, heterocyclic headgroups, and some unusual headgroups. This review summarizes recent research results concerning the nature (such as the structure and shape of cationic headgroup) and density (such as the number and the spacing of cationic headgroup) of head functional groups for improving the design of efficient cationic lipids to overcome the critical barriers of in vitro and in vivo transfection.
Transformation of biblical, mythological and folklore models in “Three fairy tales of the winged, three-headed, fire-breathing Serpent” by Radiy Pogodin

Field: Arts and Humanities (Social Sciences)

The contemporary fairy tale continues the traditions of previous fairy tales to bring good, teach and entertain, but already through the transformation of biblical, mythological and folklore models, the prism of the author’s experience and his life position. We propose a new look at the mythopoetic space of “Three fairy tales of the winged, three-headed, fire-breathing Serpent” by Radiy Pogodin (1989) through their holistic analysis, revealing their mythopoetic specificity and artistic originality. Comprehension of archetypal plot features, work mythological subtext, charac-ters system in fairy tales, their intertextual connections make it possible to reveal the deep content layers of the work under consideration. Fairy tales filled with mythological archaics easily incor-porate modern realities, so that the artistic world of R. Pogodin’s literary fairy tales is a unity of ancient archetypal models with renewing, sometimes acutely relevant motives. The system of my-thologemes and binary oppositions, mythological allegories and allusions form the author’s world model. Mythopoetic plot sketches and archetypal prototypes largely determine the semantic poly-semy and artistic complexity of R. Pogodin’s fairy tales. R. Pogodin’s work, being a descendant of a folk tale, continues and develops its genre features, forcing us to perceive a fairytale miracle as a part of our life in its everyday details and details. The central fabulous image – the Serpent, due to its many-sidedness and ambiguity, becomes the embodiment of biblical, folklore and mythological motives, forcing a person to direct his gaze into the depths of his soul. The semantic ambiguity and artistic complexity of the work allows us to assume its appeal to a readership of different ages.
Systematic administration and analysis of verbal fluency tasks: Preliminary evidence for reliable exploration of processes underlying task performance

Field: Psychology (Social Sciences)

Verbal fluency (VF) tasks are typically scored by the number of acceptable words generated within an allotted time (i.e., total score). However, total scores do not provide insight into verbal and executive processes underlying VF task performance. Further analyses have been implemented to increase the analytical power of VF tasks, but systematic scoring guidelines are needed. We generated instructions for administration, scoring, and analyses of total scores, errors, temporal parameters, clustering, and switching with strong inter-rater reliability. To investigate the reliability of the proposed analysis, we modeled the performance of Finnish-speaking older adults (N = 50) in phonemic (/k/, /a/, and / p/) and semantic (animals) categories. Our results are in line with previous studies: We observed a higher performance on semantic than phonemic fluency (p=&lt;0.001, d=0.91) and significant effects for education (p=&lt;0.001, d=1.11) and gender (p=&lt;0.001, d=-1.11), but not for age (p=.10, d=0.48). Most errors were repetitions. Performance declined over the allotted time frame as measured in 15- second segments (all p’s &lt;0.001 with medium to large effect sizes). Task congruent clustering and switching were productive strategies (all p’s &lt;0.001 with large effect sizes), and participants generated task discrepant clusters in both phonemic (p=.004, d=0.69) and semantic tasks (p=.66, d=0.18). The results substantiate the proposed method, providing evidence that these guidelines are a reliable starting point for VF task performance analyses in various clinical populations investigating VF task performance in depth.
Biographical profile of practising veterinarians in South Africa.

Field: Veterinary (Health Sciences)

To identify the current South African practising veterinarians' profile, a survey was conducted by means of a questionnaire in 1992. The list of registered veterinarians according to the South African Veterinary Board was used as a frame for the sample. Five hundred questionnaires were processed. The general profile of a practising veterinarian in South Africa was male, between 30-40 years of age, city-dweller, English speaking and working in a mixed practice.
On-task theta power is correlated to motor imagery performance

Field: Neuroscience (Life Sciences)

This study aimed to evaluate on-task electroencephalographic spectral measures and its correlation to performance during a motor imagery (MI) task. By investigating this aspect, we hope to understand what makes some individuals MI "illliterates". Eighteen healthy subjects performed an experimental task whereby a cursor was moved to one of two targets (left and right) using only MI of the left and right hands. To evaluate the effect of aptitude, performance was measured as percentage of correct movement to target, and Mahalanobis distances were calculated between whole-scalp spectral patterns during left and right motor imagery. Then the correlation between performance and Mahalanobis distance was investigated for central, and whole-head topographies using Spearman's correlations. In central topographies, distances on alpha band were positively correlated with performance (ρ=0.562, p=0.032), while distances on theta band were negatively correlated to performance (ρ--0.648, p=0.018) in whole-head maps. The investigation of on-task whole-scalp differences allows a holistic comprehension of the neural basis of motor imagery, as well as how this leads to performance variations.
Back to the Future: Rising to the Semmelweis Challenge in Hand Hygiene

Field: Health Professions (Health Sciences)

Hand hygiene is the single most important intervention for reducing healthcare associated infections and preventing the spread of antimicrobial resistance. This sentence begins most publications regarding hand hygiene in the medical literature. But why - as we mark 150 years since the publication of Ignaz Semmelweis' landmark monograph on the subject - do we continue to repeat it? One might be tempted to regard it as a truism. However, while tremendous progress has certainly been made in this field, a significant amount of work is yet to be done in both strengthening the evidence regarding the impact of hand hygiene and maximizing its implementation. Hand hygiene cannot yet be taken for granted. This article summarizes historical perspectives, dynamics of microbial colonization and efficacy of hand cleansing methods and agents, elements and impacts of successful hand hygiene promotion, as well as scale-up and sustainability. We also explore hand hygiene myths and current challenges such as monitoring, behavior change, patient participation and research priorities.
Domain-specific variation in hemagglutinin-specific T-cell responses elicited by licensed seasonal influenza vaccines (106.11)

Field: Medicine (Health Sciences)

Abstract Persistent antigenic drift in influenza hemagglutinin (HA) results in the emergence of serologically novel influenza viruses that result in seasonal epidemics globally. While the globular domain of the HA antigen is the primary repository of drift mutations, the viral-fusion domain is highly conserved. T cells are being increasingly recognized as a significant component of influenza immunity in humans and may target variant regions of HA that are not effectively targeted by type-specific antibodies. While a trivalent inactivated influenza vaccine (TIV) and a live-attenuated influenza vaccine (LAIV) are now licensed for use in humans, their comparative ability to elicit T cell responses against influenza HA is not well understood: specifically, the relative magnitude of T cell responses elicited by TIV and LAIV and their domain-specificity toward HA regions is unknown. In this study, we systematically compare immune responses elicited by TIV and LAIV in a cohort of healthy adults (18 to 49 years old) against the rapidly evolving H3N2 HA antigen. Data suggests TIV elicits higher geometric mean antibody titers than LAIV; whereas, LAIV elicits superior T cell responses. Importantly, the two vaccines vary significantly in their ability to elicit T cell responses targeting the variant and conserved regions of HA. These results have important implications for the deployment of influenza vaccines in years of antigenic mismatch and shift.