jimnoneill/paper-to-field-training huggingface dataset:
Neonatal Clinical Outcomes: a Comparative Analysis

Field: Medicine (Health Sciences)

The most popular neonatal clinical outcomes, which are blood pH (PH), base excess (BE) and Apgar after 5 minutes from birth (AP5), may provide contrasting information. Thus, aim of the paper is to perform a critical evaluation and comparison of PH, BE and AP5. Reliability of neonatal clinical outcomes was evaluated in relation to perinatal features. Neonatal and fetal cardiotocographic data of 391 newborns (CTU-CHB Intrapartum Cardiotocography Database) were analyzed. Newborns were classified as positive (i.e., as showing critical conditions) if PH<7.10 or BE<-10mmol/l or AP5<7, as negative (i.e., as showing healthy conditions) otherwise. Agreement between pairs of neonatal clinical outcomes was evaluated by computing the correlation coefficient. Fetal decelerations were characterized in terms of rate of occurrence, depth, mean, duration, and area. Correlation between PH and BE, PH and AP5 and BE and AP5 was 0.83, 0.45 and 0.38 (P<0.01), respectively; 329 newborns (84%) were equally classified by all neonatal clinical outcomes, 5 as positive and 324 as negative. Deceleration depth and rate of occurrence were comparable among positive/negative classes, while deceleration mean, duration and area were systematically higher in the positive than in the negative classes, also statistically only for PH classification. Positive class by PH counted the highest number of small newborns; large newborns were similarly distributed over all positive classes. Objective neonatal clinical outcomes, and in particular PH, seems to be more reliable than subjective clinical outcomes, and thus should be preferable for describing neonatal health status.
GROWTH AND PROSPECTS OF SYSTEM BANKING IN ROMANIA

Field: Economics, Econometrics and Finance (Social Sciences)

The years of crisis were characterized by a moderation of the lending activity in Romania, banks have changed their focus from a rapid expansion towards a strategy determined by caution. The credit institutions have adapted the strategy, the territorial expansion plans, the product portfolio and switched to a more careful control of the operating costs. The purpose of this paper is to review status of the banking sector in Romania, compared with the data obtained in the EU countries. We will examine the structure indicators, the indicators measuring the degree of development and competition as well as the indicators measuring the performance of the banking system in Romania. The study period was 2000-2012
An 8-Gb/s capacitively coupled receiver with high common-mode rejection for uncoded data

Field: Engineering (Physical Sciences)

An 8-Gb/s receiver is demonstrated in 0.35-/spl mu/m SiGe with two on-chip 60-fF ac-coupling capacitors. These capacitors are formed by on-chip metal layers and have a breakdown voltage of at least /spl plusmn/690 V, which is the dc input range of the receiver. The receiver especially resists strong ac common-mode edges with a slew rate up to 4V/ns for enhanced EMI rejection. The self-clocked quantized feedback technique used, features uncoded data that contains long sequences of consecutive identical digits or ac-unbalanced data. The differential input sensitivity is 0.5-1.1Vpp with a supply voltage between 2.5 and 3.5 V.
Hurdles Faced in Getting a Clinical Biochemistry Laboratory Accredited by NABL in Government Setup: Our Experience

Field: Health Professions (Health Sciences)

Diagnostic care is the heart of the healthcare management system.Clinical laboratories that are accredited by National Accreditation Board for Testing and Calibration Laboratories (NABL) get worldwide acceptance.Accreditation is an attempt to encourage diagnostic laboratories performing basic tests to adopt quality practices, thus improving healthcare system at grass root level in the country.A large number of laboratories are now accredited, but majority of them are in private sector.Very few clinical laboratories associated with government organization participate and are able to achieve accreditation by NABL.Fortunately, our laboratory is one of them.With the experience gained during the process of getting NABL accreditation, we feel competent enough to comment upon and summarize the areas that may present difficulty in the process.We hope that most of the laboratory personnel working in the government organization will identify with our experience and get prepared as well as motivated to get their laboratory accredited by NABL.
Four-year clinical remission of type 1 diabetes mellitus in two patients treated with sitagliptin and vitamin D3

Field: Medicine (Health Sciences)

Summary Type 1 diabetes mellitus (T1DM) is a chronic disease characterized by autoimmune destruction of pancreatic beta cells and inadequate insulin production. Remission criteria in T1DM take into account serum levels of C-peptide and glycosylated hemoglobin, as well as the dose of insulin administered to the patient. However, remission of T1DM lasting longer than 1 year is rare. We describe here the cases of two young women who presented with positive glutamic acid decarboxylase (GAD) antibody and classic clinical manifestations of T1DM. Both patients had a prior history of Hashimoto’s thyroiditis. They were initially treated with a basal-bolus regimen of insulin (glargine and lispro/glulisine). Once their blood glucose levels were controlled, they were started on oral sitagliptin 100 mg and vitamin D3 5000 IU daily. After this therapy, both patients achieved clinical diabetes remission for 4 years, along with a decrease in anti-GAD antibody levels. These benefits were probably associated with immunological effects of these medications. Inhibition of dipeptidyl peptidase 4 (DPP-4) in animal models deregulates Th1 immune response, increases secretion of Th2 cytokines, activates CD4 + CD25 + FoxP3 + regulatory T-cells and prevents IL-17 production. Vitamin D3 also activates CD4 + CD25 + FoxP3 + regulatory T-cells, and these medications combined can improve the immune response in patients with new-onset T1DM and probably promote sustained clinical remission. Learning points: The use of sitagliptin and vitamin D3 in patients with new-onset type 1 diabetes mellitus (T1DM) may help decrease the daily insulin requirement by delaying beta cell loss and improving endogenous insulin production. The use of sitagliptin and vitamin D3 in new-onset T1DM could help regulate the imbalance between Th17 and Treg cells. Age 14 years or above, absence of ketoacidosis and positive C-peptide levels in patients with T1DM are good criteria to predict prolonged T1DM remission. The determination of anti-GAD antibodies and C-peptide levels could be helpful in the follow-up of patients in use of sitagliptin and vitamin D3, which could be associated with prolonged T1DM clinical remission.
Das Drama der zweiten Geburt

Field: Psychology (Social Sciences)

Abstract This paper gives a reading and an interpretation of a psychotherapeutic session between a child (5 year old Ina) and her therapist, drawing on the theory of re-enactment and dramaturgy in performance and theatre studies. The main thesis is that in their interaction child and therapist re-enact the trauma of the abandoned baby in a “play within the play”. Thus significant moments of meeting – in crossing the borders between (mimetic) play and reality – reveal how aggressive emotions are re-enacted and dissolve the rhythms and impact of their negative power.
Stochastic Differential Game of Sustainable Allocation Strategy for Idle Emergency Supplies in Post-Disaster Management

Field: Decision Sciences (Social Sciences)

This study aims to explore allocation strategies for idle emergency supplies in a “demander–platform–supplier” supply chain system along with government regulation during the post-disaster recovery period. Allocation of emergency supplies is a complex task that encompasses resource allocation before and after disasters. It is essential to reduce losses in disaster-stricken areas and support development during post-disaster recovery. However, there is often an excessive supply of emergency materials and a mismatch between supply and demand sides in downstream supply chains, which may lead to severe waste and difficulties in recovering surplus materials. This paper takes idle emergency resource sharing level and corporate social responsibility goodwill as endogenous variables. The allocation approaches are dynamically evaluated by incorporating random elements that influence the endogenous variables. Three stochastic differential games are introduced to examine the interactions between the players. The centralized decision-making satisfies the consistency of overall and individual rationalities at any time in the emergency material allocation process, promoting the optimal sharing levels of emergency materials and overall profits. The decentralized decision-making with cost-sharing contracts achieves local optima and increases the dual marginal effect of the emergency industry chain. This paper incorporates the sharing economy into emergency management, showing how technology-driven sharing platforms can optimize resource utilization. The results suggest introducing cost-sharing contracts between demanders and suppliers can enhance collaboration and effort, leading to better resource allocation and increased efficiency. It contributes to sustainability by promoting efficient resource utilization through idle emergency resource sharing. By optimizing allocation strategies and enhancing corporate social responsibility, the study fosters the long-term viability and resilience of the supply chain system in post-disaster management.
SYNTHESISATION OF STORY TELLING AND TECHNOLOGY

Field: Arts and Humanities (Social Sciences)

Storytelling in the African epistemological context is known for its ability to communicate morals and values, and is instrumental in conflict resolution and peace building. Conversely, the strength of modern technology is on mass distribution of products. However, a relationship that exists between tradition and modern technology has not exhausted its potential of being innovative. In order to contribute to the discourse relating to the role of technology in the preservation, restoration and dissemination of indigenous knowledge, the view presented in this article explores the nature and use of certain technologies and their communication strategies within a personalized domestic setting. Herein traditional content in a technological package is presented. This article therefore, seeks to explore ways that speak to the need to deconstruct African identity and tradition and poses the question â€˜Who am Iâ€™ as it sits at the heart of being innovative with modern technology.
Assessment of maturity of mining industry simulation

Field: Decision Sciences (Social Sciences)

Mining is a mature user of high technology. However, the maturity of mining simulation use is unclear. This paper compares mining to other industries to assess maturity. Simulation technology has been implemented at varying levels of complexity, sophistication and success. Rapid advances in hardware and software make low cost, mass market and high end small market computer based simulations readily accessible. When mining is compared to other industries, simulation acceptance appears immature, particularly in the areas of risk and hazard reduction, simulation design, operational command and control and a formal implementation framework. The question asked by this paper is: 'What is the level of maturity of interactive computer based simulation in the mining industry when compared to other industries?' The paper reviews some of the many interactive visualisations and simulations developed for the mining industry. The outcome is a basic qualitative maturity model of simulation in the mining industry as of 2010.
Basiliximab vs antithymocyte globulin after lung transplantation: A national review

Field: Medicine (Health Sciences)

Introduction: Basiliximab (BAS) is an interleukin-2 monoclonal antibody used as induction therapy in kidney and liver transplantation. BAS use after lung transplantation (LTx) has grown over the years and supplanted antithymocyte globulin (ATG) as main induction immunosuppression (IIS). Few studies have compared them. Objectives: Compare the efficacy and safety between BAS and ATG in LTX. Methods: Retrospective study of all LTx done in Portugal between January 2016 and December 2019. Three groups were made according to IIS status: BAS, ATG or no induction (NI). Dosages of other immunosuppressive drugs were similar. Occurrence of rejection, cytomegalovirus (CMV) infection, side effects, early allograft dysfunction (EAD) (first 72 hours), pneumonia and death were assessed during first year after LTx. Results were compared with qui-square test. Results: A total of 124 patients were divided in 3 groups: 61 (49.2%) BAS; 43 (34.7%) ATG; 20 (16.1%) NI. Age and indication for LTx were similar. Side effects were reported only in ATG group [20 (46,5%)]. Incidence of pneumonia and CMV was: 65.6% BAS; 72.1% ATG; 85% NI and 18% BAS; 25.6% ATG; 5% NI; respectively. Number of rejections was 10 (16,4%) in BAS, 23 (27.9%) in ATG and 2 (10%) in NI. 70.1% of BAS group rejections and 50% of ATG occurred in first 3 months. EAD was seen in 16.4% of BAS, 11.6% ATG, and 50% NI. Number of deaths was 3 (7.0%) for BAS, 5 (8.2%) for ATG and 9 (45%) for NI groups. EAD and deaths were lower in BAS and ATG groups (p<0.05). Conclusion: BAS had a better safety profile in LTx than ATG and there was no difference between rejection episodes, EAD, infection or survival. This study also reinforces the importance of IIS strategies.
Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process

Field: Medicine (Health Sciences)

Abstract Background Globally, medical cannabis legalization has increased in recent years and medical cannabis is commonly used to treat chronic pain. However, there are few randomized control trials studying medical cannabis indicating expert guidance on how to dose and administer medical cannabis safely and effectively is needed. Methods Using a multistage modified Delphi process, twenty global experts across nine countries developed consensus-based recommendations on how to dose and administer medical cannabis in patients with chronic pain. Results There was consensus that medical cannabis may be considered for patients experiencing neuropathic, inflammatory, nociplastic, and mixed pain. Three treatment protocols were developed. A routine protocol where the clinician initiates the patient on a CBD-predominant variety at a dose of 5 mg CBD twice daily and titrates the CBD-predominant dose by 10 mg every 2 to 3 days until the patient reaches their goals, or up to 40 mg/day. At a CBD-predominant dose of 40 mg/day, clinicians may consider adding THC at 2.5 mg and titrate by 2.5 mg every 2 to 7 days until a maximum daily dose of 40 mg/day of THC. A conservative protocol where the clinician initiates the patient on a CBD-predominant variety at a dose of 5 mg once daily and titrates the CBD-predominant dose by 10 mg every 2 to 3 days until the patient reaches their goals, or up to 40 mg/day. At a CBD-predominant dose of 40 mg/day, clinicians may consider adding THC at 1 mg/day and titrate by 1 mg every 7 days until a maximum daily dose of 40 mg/day of THC. A rapid protocol where the clinician initiates the patient on a balanced THC:CBD variety at 2.5–5 mg of each cannabinoid once or twice daily and titrates by 2.5–5 mg of each cannabinoid every 2 to 3 days until the patient reaches his/her goals or to a maximum THC dose of 40 mg/day. Conclusions In summary, using a modified Delphi process, expert consensus-based recommendations were developed on how to dose and administer medical cannabis for the treatment of patients with chronic pain.
Protective effects of apigenin against furan-induced toxicity in mice

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Furan, a food contaminant formed by heating, is possibly carcinogenic to humans. In this study, we discussed the effect of administration of apigenin on furan-induced toxicity by determining the ROS content, oxidative damage, cytokine levels, DNA damage, and the liver and kidney damage in a mouse model.
Population genetic analyses reveal female reproductive philopatry in the oviparous Port Jackson shark

Field: Agricultural and Biological Sciences (Life Sciences)

Restricted gene flow and reproductive philopatry are increasingly being described in marine predators such as sharks. However, observing shark reproductive behaviour in situ is problematic because of issues associated with sampling in the marine environment. As such, molecular tools have become fundamental to unravelling complex mating behaviours. In this study, we examined patterns of genetic structure in the oviparous Port Jackson shark (Heterodontus portusjacksoni) using 10 microsatellite loci and the mitochondrial (mt)DNA control region. Patterns of genetic structure were investigated between breeding aggregations in Sydney and Jervis Bay, as well as between two sites within Jervis Bay. Significant genetic differentiation was detected between Sydney and Jervis Bay using mtDNA, but no structure was observed within Jervis Bay. No significant genetic differentiation was found with microsatellites within or between aggregations. Mean assignment index values were significantly higher for females than males in Jervis Bay, but not in Sydney. Both females and males migrate inshore during the Austral winter for breeding, but it appears females may exhibit higher levels of reproductive philopatry than males. This is the first study to document reproductive philopatry in an oviparous shark, highlighting the importance of conserving and appropriately managing breeding sites for H. portusjacksoni and potentially other oviparous shark species.
Comparative studies of regional CNS blood flow and evoked potentials in the cat. Effects of hypotensive ischemia on somatosensory evoked potentials in cerebral cortex and spinal cord.

Field: Neuroscience (Life Sciences)

Functional resistance to graded hypotensive ischemia of various segments of the somatosensory pathway was determined in anesthetized cats by repeated concurrent recordings of regional blood flow measured by hydrogen clearance, and evoked potentials (EPs), of dorsal horn of lumbar spinal cord and cerebral cortex. During normal resting CNS blood flow (CBF), there were significant successive reductions of EP amplitudes, recorded from presynaptic spinal components (634, 424-949 microV; re-linearized mean and 95% confidence limits of log-transformed data) compared to postsynaptic spinal (359, 247-522 microV) and presynaptic cortical (50, 32-79 microV) and to postsynaptic cortical components (33, 22-50 microV). During ischemia amplitudes of EPs in spinal cord and cerebral cortex showed significantly different behaviors. The presynaptic spinal component was virtually independent of regional blood flow down to 12 percent of resting values, the postsynaptic cortical component exhibited strongest positive correlations (r = 0.45) with flow. In both regions postsynaptic amplitude was more sensitive to flow changes than respective presynaptic amplitudes. Despite similar regression coefficients for intermediate segments of somatosensory pathway, only postsynaptic spinal components were significantly correlated (r = 0.40) with regional flow. Presynaptic cortical amplitudes were variable and no significant flow dependence was demonstrated. Results suggested that in comparable degrees of regional ischemia of CNS functional integrity is determined by numbers of synaptic transmissions involved locally. Comparatively simple structures, e.g. the spinal cord, are less susceptible to ischemia and complex neuronal networks, e.g. the cerebral cortex, are more susceptible.
Electrochemical Mechanism Underlying Lithium Plating in Batteries: Non-Invasive Detection and Mitigation

Field: Engineering (Physical Sciences)

Efficient, sustainable, safe, and portable energy storage technologies are required to reduce global dependence on fossil fuels. Lithium-ion batteries satisfy the need for reliability, high energy density, and power density in electrical transportation. Despite these advantages, lithium plating, i.e., the accumulation of metallic lithium on the graphite anode surface during rapid charging or at low temperatures, is an insidious failure mechanism that limits battery performance. Lithium plating significantly shortens the battery’s life and rapidly reduces capacity, limiting the widespread adoption of electrical vehicles. When lithium plating is extreme, it can develop lithium dendrites, which may pass through the separator and lead to an internal short circuit and the subsequent thermal runaway damage of the cell. Over the last two decades, a large number of published studies have focused on understanding the mechanisms underlying lithium plating and on approaches to mitigate its harmful effects. Nevertheless, the physics underlying lithium plating still needs to be clarified. There is a lack of real-time techniques to accurately detect and quantify lithium plating. Real-time detection is essential for alleviating lithium plating-induced failure modes. Several strategies have been explored to minimize plating and its effect on battery life and safety, such as electrolyte design, anode structure design, and hybridized charging protocol design. We summarize the current developments and the different reported hypotheses regarding plating mechanisms, the influence of environmental and electrochemical conditions on plating, recent developments in electrochemical detection methods and their potential for real-time detection, and plating mitigation techniques. The advantages and concerns associated with different electrochemical detection and mitigation techniques are also highlighted. Lastly, we discuss outstanding technical issues and possible future research directions to encourage the development of novel ideas and methods to prevent lithium plating.
Comment on cp-2021-146

Field: Environmental Science (Physical Sciences)

Abstract. In 2013, the Intergovernmental Panel on Climate Change concluded that Northern Hemisphere temperatures had reached levels unprecedented in at least 1400 years. The 2021 report now sees global mean temperatures rising to levels unprecedented in over 100 000 years. This Technical Note briefly explains the reasons behind this major change. Namely, the new assessment reflects additional global warming that occurred between the two reports and improved paleotemperature reconstructions that extend further back in time. In addition to past and recent warming, the conclusion also considers multi-century future warming, which thereby enables a direct comparison with paleotemperature reconstructions on multi-century time scales.
Solanum tuberosum LOTID 242167

Field: Agricultural and Biological Sciences (Life Sciences)

Plant Genetic Resource.
Taxonomy: Solanum tuberosum
Common name(s): Potato
Conserved by: Centro Internacional de la Papa (CIP), Peru
Local sample unique identifier: LOTID 242167
Method of creation: In-house copy
Date: 2009
Other identifiers: n/a,CIP 715451
Historical: Yes
Biological status: Traditional cultivar/landrace
MLS status: Included