jimnoneill/paper-to-field-training huggingface dataset:
Video-Based Head Tracking for High-Performance Games

Field: Computer Science (Physical Sciences)

The recent advent of video-based tracking technologies allowed to bring natural head motion to any 3D application, including games. However, video tracking is a CPU-intensive process, which may have a negative impact on game performance. In this work, we examine this impact for different types of 3D content, using a game prototype built with two advanced components, CryENGINE2 platform and faceAPI head tracking system. Our findings indicate that cost of video tracking is negligible. We provide detail on our system implementation and performance analysis. Also, we present a number of new techniques of controlling user avatars in social 3D games, based on head motion.
Deformation Monitoring in an Alpine Mining Area in the Tianshan Mountains Based on SBAS‐InSAR Technology

Field: Earth and Planetary Sciences (Physical Sciences)

The fragile habitat of alpine mining areas can be greatly affected by surface disturbances caused by mining activities, particularly open‐pit mining activities, which greatly affect the periglacial environment. SBAS‐InSAR technology enables the processing of SAR images to obtain highly accurate surface deformation information. This paper applied SBAS‐InSAR technology to obtain three years of surface subsidence information based on the 89‐scene Sentinel‐1A SLC products, covering a mining area (tailings and active areas) in the Tianshan Mountains and its surroundings from 25 th December 2017 to 2 nd January 2021. The data were adopted to analyze the characteristics of deformation in the study region and the mining areas, and the subsidence accumulation was compared with field GNSS observation results to verify its accuracy. The results showed that the study area settled significantly, with a maximum settlement rate of −44.80 mm/a and a maximum uplift rate of 28.04 mm/a. The maximum settlement and accumulation of the whole study area over the three‐year period were −129.39 mm and 60.49 mm, respectively. The mining area had a settlement value of over 80 mm over the three years. Significantly, the settlement rates of the tailings and active areas were −35 mm/a and −40 mm/a, respectively. Debris accumulation in the eastern portion of the tailings and active areas near the mountain was serious, with accumulation rates of 25 mm/a and 20 mm/a, respectively, and both had accumulation amounts of around 70 mm. For mine tailing pile areas with river flows, the pile locations and environmental restoration should be appropriately adjusted at a later stage. For gravel pile areas, regular cleaning should be carried out, especially around the mining site and at the tunnel entrances and exits, and long‐term deformation monitoring of these areas should be carried out to ensure safe operation of the mining site. The SBAS‐InSAR measurements were able to yield deformations with high accuracies over a wide area and cost less human and financial resources than the GNSS measurement method. Furthermore, the measurement results were more macroscopic, with great application value for surface subsidence monitoring in alpine areas.
A Brief Model Overview of Personalized Recommendation to Citizens in the Health‐Care Industry

Field: Computer Science (Physical Sciences)

The Recommender System is one of the aspiring domains in today's information and communication technology world. The recommender system does a metric analysis and determine if the recommended product is relevant or not for a user. A recommender system analyzes a large amount of unstructured data for intelligent mining. In recommender system, the procedure of delivering an explanation is based on an intelligent collaborative filtering process for decision making. In this context, the collaborative filtering-based recommendation system model has become an indispensable tool for future decision insemination to end-user. The recommender system avails valuable information from citizens, doctors, pharmacists, and market analysts to create a datastore where the decision logic and collaborative filtering can be applied to disseminate recommendation to the citizens for the service they need in due course of time. This chapter provides an insight into the implementation of the recommender system in both tangible and non-tangible products as well as the service care industry. With the implementation of this recommender system model, the remedial solution for citizens will gain a new momentum. The recent research needs a large volume of products or medical data to ensure its quality and trustworthiness. By the advancement of research, this model will derive valuable outcome. This model is a context-specific recommendation system that will grow further after data collection and learning. In this chapter, we provide the detailed theoretical framework of the flow chart-based recommender system in the health care model that strongly supports transparency, trustworthiness, and validity.
Polyneuritis and oral contraceptives.

Field: Medicine (Health Sciences)

BRiTisH 879 but when assessing symptoms that are by definition subjective the patients' opinions are of importance.'Whether or not symptomatic improvement correlates with objective measurements is another matter.It would appear to be particularly important to consider patients' opinions in fluctua- ting conditions such as bronchospasm, where they may well be able to give an overall im- pression of their clinical condition during a period of time, while isolated objective tests only give information on a few minutes separated by many weeks.Another example occurred in the same issue of the B.M.7. in a review of inhaled steroids for asthma (" Any Questions ?" 18 September, p. 691).Admittedly the trials quoted differed in many ways, but the studies relying mainly on subjective assessments2-5 found that inhalations of hydrocortisone acetate were significantly better than placebo while trials utilizing isolated lung function tests'7 were unable to demonstrate a difference between the two regimens.In the trial of breathing exercises it is possible that cough and sputum were worse in the treated group owing to the higher incidence of colds (58% as opposed to 40%), and that the patients took this into considera- tion when they declared an overall improve- ment in the symptom of dyspnoea after breathing exercises.It was, of course, impossible to conduct a double-blind trial on breathing exercises, and Stewart and Anderson8 are probably quite correct in stating that such exercises produce little or no benefit and that apparent im- provement was due to gratitude for extra attention.Nevertheless, it is worth mentioning that in trials of this sort where assessments of subjective symptoms are made over a prolonged period due weight should be given to patients' opinions, as isolated objective tests have considerable limitations.-Iam, etc.,
Cost effective, robust, and reliable coupled separation techniques for the identification and quantification of phospholipids in complex biological matrices: Application to insects

Field: Chemistry (Physical Sciences)

The quantification of phospholipid classes and the determination of their molecular structures are crucial in physiological and medical studies. This paper's target analytes are cell membrane phospholipids, which play an important role in the seasonal acclimation processes of poikilothermic organisms. We introduce a set of simple and cost‐effective analytical methods that enable efficient characterization and quantification of particular phospholipid classes and the identification and relative distribution of the individual phospholipid species. The analytical approach involves solid‐phase extraction and high‐performance thin‐layer chromatography, which facilitate the separation of particular lipid classes. The obtained fractions are further transesterified to fatty acid methyl esters and subjected to gas chromatography coupled to flame ionization detection, which enables the determination of the position of double bonds. Phospholipid species separation is achieved by high‐performance liquid chromatography with mass spectrometry, which gives information about the headgroup moiety and attached fatty acids. The total content of each phospholipids class is assessed by phosphorus determination by UV spectrophotometry. The simultaneous analysis of phosphorus, fatty acid residues, and phospholipid species provides detailed information about phospholipid composition. Evaluation of these coupled methods was achieved by application to an insect model, Pyrrhocoris apterus . High correlation was observed between fatty acid compositions as determined by gas chromatography and high‐performance liquid chromatography analysis.
Universal hip ultrasound screening and preventive treatment in Mongolia: interventions for improvement

Field: Health Professions (Health Sciences)

Developmental dysplasia of the hip (DDH) is a significant health problem that can lead to lifelong treated or disabled individuals if the diagnosis is missed in the first weeks of life. In Mongolia, an ultrasonic method (Graf) of DDH screening was introduced, piloted, and expanded as a nationwide newborn screening program in 2010. Trained neonatologists or pediatricians perform the hip ultrasound screening following standardized procedures and are responsible for the flexion-abduction treatment, if necessary. Complete documentation of all cases is mandatory. Screening, follow-up monitoring, and flexionabduction treatment are offered free of charge. The program aims to screen every newborn baby using hip ultrasound and provide early preventive treatment to eliminate disability due to DDH. As Mongolia is the first Asian country to launch a program of universal ultrasound screening for DDH, we needed to determine its coverage and treatment rate. During the implementation of the screening, we documented that physiological immaturity (Graf’s Type 2a) hips degrade and develop DDH. In these cases, unfavorable mechanical conditions may exist after birth since traditional Mongolian swaddling requires a tight wrapping with stretched legs, and the hips are held in an adducted position. Therefore, traditional swaddling possibly increases the risk for DDH. This hypothesis was tested with a randomized controlled trial. Another challenge of the nationwide screening program was a human resources issue. Because resources are limited, adequately trained physicians are not always available, especially in remote rural areas. Thus we compared the quality and interpretation of hip ultrasound between trained nurses and junior physicians with no previous ultrasound experiences. This thesis demonstrated that a simplified diagnostic and therapeutic framework for hip ultrasound DDH screening for newborns was successfully deployed in Mongolia, providing high surveillance coverage and appropriate treatment. This Mongolian experience may support further international discussion on universal ultrasound screening using the Graf method for DDH. Furthermore, the thesis provides evidence that traditional Mongolian swaddling where legs are extended, and hips are in extension and adduction position increases the risk for DDH; nurses can obtain standard hip sonograms according to the Graf method with equal quality as junior physicians after receiving standard training. These results allow us to improve the coverage and quality of the nationwide screening program in Mongolia.
The times they are a‐changin’: the Cachexia Conference goes annual

Field: Medicine (Health Sciences)

The field of cachexia and muscle wasting research has started to move, slowly but steadily, and large and small companies alike are increasing their efforts into the development of new drug therapies for cachexia, sarcopenia and frailty. Recent research has focused on novel screening tools1 and biomarker research to enable an early diagnosis of wasting,2, 3 but also on the pathophysiological understanding of the wasting process4, 5 nutrition,6, 7 exercise, particularly in cachectic cancer patients,8-10 and novel therapeutic approaches.11-13 Even though the pathophysiological understanding is making rapid progress – if not by the minute or day, then by the week for sure – recent phase III trials have failed unfortunately to translate gain in muscle mass into gain in muscle function, i.e. more exercise capacity or strength or better stair climbing power. ‘Come senators, congressmen Please heed the call Don't stand in the doorway Don't block up the hall For he that gets hurt Will be he who has stalled There's a battle outside And it is ragin'. It'll soon shake your windows And rattle your walls For the times they are a-changin'. We would like to make the conference a very hands-on meeting with (likely) no parallel sessions and a programme made by the audience. We hereby call for your session proposals to be send to Mrs Monika Diek at the SCWD office (conference2016@cachexia.info). Please do so by 15th April, 2016. As we start to go annual, we will still hold a big Cachexia Conference for 3 full days (as done in Paris) every 2 years, and every other 2 years the meeting is a 2-day affair. As the field gains momentum, we may change this in the future, but fort he time being this seems tob e prudent. So please, safe the date and come to Berlin on 10/11 December, 2016. And send us your session proposals. The authors of this manuscript certify that they comply with the principles of ethical publishing in the Journal of Cachexia, Sarcopenia, and Muscle 2015.14 None declared.
Error Analysis of Unattended Ground Sensor Operators' Reports.

Field: Decision Sciences (Social Sciences)

Abstract : Recent field exercises have provided unattended ground sensor (UGS) activation data from sensors employed in grid arrays. Use of grid arrays has provided increased flexibility to the UGS program, but also has created new problems. Recent research has shown a relatively high frequency of errors committed by the UGS operator while monitoring grid arrays. The limited amount of training introduced has proven successful in improving operator performance. However, a need for further refinement has been recognized. In order to improve grid array monitoring performance, it has been necessary to expand our knowledge concerning grid arrays and to utilize experience gained from the previous research. The initial step in this process was an error analysis of UGS operator performance data collected from previous studies. This error analysis will help establish the goals and objectives of the training effort planned as a major project.
Spectroscopic, Electrochemical, and DFT Studies of Oxo‐Centered Triruthenium Cluster Complexes with a Bis(tridentate) Triazine Ligand

Field: Chemistry (Physical Sciences)

Abstract Oxo‐centered triruthenium–acetate complexes with a tridentate or bis(tridentate) triazine ligand have been prepared by the reaction of [Ru 3 O(OAc) 6 (py) 2 (CH 3 OH)] + ([ 1 ] + ) with a triazine ligand [3‐(2‐pyridyl)‐1,2,4‐triazine (pytz), 3‐(2‐pyrimidinyl)‐1,2,4‐triazine (pmtz), or 5,5′,6,6′‐tetramethyl‐3,3′‐bi‐1,2,4‐triazine (bdmt)]. The dimeric complex [{Ru 3 O(OAc) 5 (py) 2 } 2 (μ 4 ‐pmtz)] 2+ ([ 5 ] 2+ ), an intercluster mixed‐valence complex ([Ru 3 III,III,II ‐pmtz‐Ru 3 III,III,III ] 2+ ) containing an asymmetric bis(tridentate) pmtz ligands involved in both μ‐η 1 (N),η 2 (N,N) and orthometalated μ‐η 1 (C),η 2 (N,N) bonding modes, was prepared by substitution of a bridging acetate in the parent Ru 3 O(OAc) 6 cluster core. Chemical or electrochemical reduction or oxidation of [ 5 ] 2+ gave one‐electron reduced product [ 5a ] + or oxidized species [ 5b ] 3+ , respectively. It is demonstrated that substitution of the bridging acetate by a triazine ligand has a remarkable impact on the electronic and redox characteristics of the triruthenium cluster derivatives. Electrochemical, UV/Vis/NIR spectra, and DFT computational studies demonstrated that there is a distinct cluster–cluster interaction between the two triruthenium cluster moieties across an asymmetric bridging bis(tridentate) triazine in the dimeric triruthenium cluster complex [ 5 ] 2+ .
How Paradoxical Leadership Affects Ambidextrous Innovation: The Role of Knowledge Sharing

Field: Business, Management and Accounting (Social Sciences)

In an increasingly dynamic and complex competitive environment, leaders are likely to face contradictory demands and ambidextrous innovation. From the perspectives of absorptive capacity and organizational inertia, we examined the relationship between paradoxical leadership and ambidextrous innovation, and the moderating role of knowledge sharing in this relationship. Participants were 306 senior or intermediate executives with innovative experience from high-technology companies in China. Results of our empirical analysis showed that paradoxical leadership was positively related to both exploratory and exploitative innovation. Knowledge sharing positively moderated both these relationships, such that, when knowledge sharing was high, stronger paradoxical leadership was correlated with more ambidextrous innovation. Theoretical and practical implications are discussed.
Limited Dose-Dependent Effects of Vedolizumab on Various Leukocyte Subsets

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

OBJECTIVES: The anti-α4β7 integrin antibody vedolizumab (VDZ) is successfully used for the treatment of inflammatory bowel diseases. However, only a subgroup of patients respond to therapy. VDZ is administered at a fixed dose, leading to a wide range of serum concentrations in patients. Previous work from our group showed a dose-dependent preferential binding of VDZ to effector compared with regulatory CD4 + T cells. Therefore, we aimed to determine the dose-dependent binding profile of VDZ to other leukocyte subsets. METHODS: We characterized α4β7 integrin expression on CD8 + T cells, CD19 + B cells, CD14 + monocytes, natural killer cells, and eosinophils from patients with inflammatory bowel disease and healthy controls. We studied the binding of VDZ to these cells at different concentrations and investigated the functional consequences for dynamic adhesion and transmigration in vitro . RESULTS: The expression of α4β7 differed between the analyzed leukocyte subsets and was significantly higher on eosinophils from inflammatory bowel disease patients compared with controls. Almost all α4β7-expressing cells from these subsets were bound by VDZ at a concentration of 10 μg/mL. Dynamic cell adhesion was significantly impaired in all subsets, but there were no dose-dependent differences in the inhibition of adhesion. DISCUSSION: Our data suggest that α4β7-expressing CD8 + T cells, CD19 + B cells, CD14 + monocytes, natural killer cells, and eosinophils are a target of VDZ. However, there do not seem to be concentration-dependent differences, regarding the effects on these cells in the clinically relevant range. Thus, the reported exposure-efficacy characteristic of VDZ can probably mainly be attributed to CD4 + T-cell subsets.
Can We Prevent Antimicrobial Resistance by Using Antimicrobials Better?

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Since their development over 60 years ago, antimicrobials have become an integral part of healthcare practice worldwide. Recently, this has been put in jeopardy by the emergence of widespread antimicrobial resistance, which is one of the major problems facing modern medicine. In the past, the development of new antimicrobials kept us one step ahead of the problem of resistance, but only three new classes of antimicrobials have reached the market in the last thirty years. A time is therefore approaching when we may not have effective treatment against bacterial infections, particularly for those that are caused by Gram-negative organisms. An important strategy to reduce the development of antimicrobial resistance is to use antimicrobials more appropriately, in ways that will prevent resistance. This involves a consideration of the pharmacokinetic and pharmacodynamics properties of antimicrobials, the possible use of combinations, and more appropriate choice of antimicrobials, which may include rapid diagnostic testing and antimicrobial cycling. Examples given in this review include Mycobacterium tuberculosis, Gram-negative and Gram-positive organisms. We shall summarise the current evidence for these strategies and outline areas for future development.
Formulation, evaluation and characterization of novel oil inclusion complex, obtained from leaves of Acorus calamus Linn to prove the neurological (Anxiolytic) potential of the drug

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Background: Acorus calamus Linn., an amphibious and amphibiotic plant used in Ayurveda, is also known as vach, sweet flag, and other names. Purpose: The present study aims to developed inclusion complex of essential oil with 2‑hydroxy propyl beta cyclodextrin and evaluate the anxiolytic activity through a light dark box model and elevated plus maze model. Material and methods: The inclusion complex is made with cyclodextrin using a variety of techniques, such as kneading, even though the essential oil has wide spectrum action. Acorus calamus oil was first extracted from freshly gathered leaves using Clevenger equipment for eight hours. The kneading method made inclusion complex, which was then dried in a desiccator for 24 h. Results: This study effort confirms anxiety studies in part due to the chemical constituent of the Acorus calamus known as asarone through GCMS, among other things. TGA, SEM, and XRD analyses are used for confirmation investigations, as well as for confirming the combination of oil with cyclodextrin. The main purpose of cyclodextrin is to improve the stability and bioavailability of the oil. This research confirms that after in vivo studies on Swiss albino mice, cyclodextrin complex with essential oil has anti-anxiety properties with better stability than a Diazepam (Standard Dose) at 1.0 mg/kg by p.o. route. Conclusion: These findings confirm the stability of 2‑hydroxy propyl beta cyclodextrin with essential oil which is valuable candidate for development of alternative anxiolytics with a lower incidence of adverse effect.
Structural basis for the ARF GAP activity and specificity of the C9orf72 complex

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The Journal of Cell Biology (JCB) and Journal of Experimental Medicine (JEM) present a two-day virtual symposium on neurodegeneration, bringing together prominent and diverse researchers for talks and poster presentations on the latest advances in fundamental and translational research on: Alzheimer’s disease (AD), Parkinson’s disease (PD), Frontotemporal dementia (FTD), Amyotrophic lateral sclerosis (ALS), and other neurodegenerative disorders. Please view posters in the Submissions tab.
AN ASSESSMENT OF THE ANALGESIC EFFECT IN LABOUR OF PETHIDINE AND 50 PER CENT NITROUS OXIDE IN OXYGEN (ENTONOX)

Field: Medicine (Health Sciences)

Summary The effectiveness in clinical practice of conventional analgesia, with pethidine and 50 per cent nitrous oxide in oxygen (Entonox) has been studied in 663 consecutive patients. More than 75 per cent of mothers stated that they had obtained little or no pain relief from pethidine in the manner in which it was administered. In comparison, nearly half the patients who received Entonox had satisfactory analgesia and the incidence of acceptable pain relief with both agents was unrelated to parity. The number of patients receiving satisfactory analgesia was disturbingly low.