jimnoneill/paper-to-field-training huggingface dataset:
Cyclic stretching promotes collagen synthesis and affects F-actin distribution in rat mesenchymal stem cells

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Recent studies have shown effects of mechanical environment on bone marrow mesenchymal stem cells (BMSC). In order to examine how BMSC and their cytoskeleton respond to mechanical stimulation, we investigated their collagen synthesis and F-actin expression. Rat BMSC were harvested from adult rats and cultured to passage 4. Then the cells were seeded onto a silicone membrane loaded with an uniaxial cyclic stretching (10%, 1 Hz) during 3, 6, 12, 24 and 36 h. The levels of collagen type I and III before and after stretching were analyzed by immunocytochemistry, and the F-actin in cytoplasm was observed by confocal microscopy. Immunocytochemistry results showed that the stretching enhanced the synthesis of collagen types I and III in BMSC after 24 h stimulation. However, a decrease in fluorescence density of F-actin was observed after the stretching in a time dependent manner. In addition, the F-actin filaments seemed much thinner than those of static cells. These results indicated that the cyclic stretching favored the synthesis of collagen types I and III, but decreased the amount of F-actin in the BMSC.
Oksim Grubu İçeren Dinükleer Fe(II) ve Mn(II) Komplekslerinin Sentezi, Karakterizasyonu, Katalaz ve Katekolaz Enzim Aktivitelerinin İncelenmesi

Field: Chemistry (Physical Sciences)

In this study, dinuclear iron(II) and manganese(II) complexes were synthesized using two different ligands containing oxime group. These new complexes have been characterized by elemental analyses, ICP-OES, FT-IR spectra, TG, magnetic susceptibility and conductivity measurements. The results suggest that the dinuclear complexes of H2L1 and H4L2 have a metal:ligand ratio of 2:2 and 2:1, respectively. Furthermore complexes were each tested both for their ability to catalyse the disproportionation of hydrogen peroxide in the presence of the added base imidazole and oxidation reaction of 3,5-di-tert-butylcatechol to the 3,5-di-tert-butylquinone presence of O2. It was found that all complexes exhibited good both catalase and catecholase activity
Air quality correlates of chronic disease mortality: Harris County, Texas 1969--1971.

Field: Medicine (Health Sciences)

Air quality correlates of chronic disease mortality in 180 census tracts of Harris County, Texas, were studied using 3 years mortality for 1969--1971. This study was designed to test with a different data base the universality of several study results which have reported significant correlations between heart disease and air pollutants. Air quality data (suspended particulates, benzene solubles, sulfur dioxide, and metals associated with particulates: copper, mercury, manganese, lead, nickel, zinc, chromium, and cadmium) were related to both sex and age adjusted crude death rates, and cause-specific death rates for age cohorts for 7 categories of heart disease, and pneumonia, asthma, cancer, tuberculosis, and accident deaths. The results of the study were in agreement with the findings of the other researchers who used national data. Suspended particulates and cadmium concentrations were found to be correlated (r=.38, .36; P less than .001) with ischemic heart disease (IHD). Many other significant correlations are reported but are not cause-specific. Socio-economic indicators were also correlated with IHD, thus confounding the issue. Further work is planned using more sophisticated statistical techniques to disentangle the relative contribution of each of these highly intercorrelated factors. No causality can be assigned at this stage, although this study, with the other cited, points to possible risk factors for IHD which need further evaluation.
The Relationships of Positive Psychological Capital, Psychological Ownership, Job Satisfaction and Job Performance

Field: Psychology (Social Sciences)

본 연구의 목적은 최근 서비스 산업의 지속적인 성장에 따른 조직운영의 효과성 개선을 위하여 공적 서비스업과 사적 서비스업에 종사하는 종업원을 대상으로 긍정심리자본, 심리적 주인의식, 직무만족 및 직무성과 간의 관계를 살펴보는 것이다. 실증분석 결과 (1) 긍정심리자본의 자기효능감, 희망, 낙관주의는 심리적 주인의식에 유의한 영향을 미치는 것으로 나타났으나, 복원력은 심리적 주인의식에 영향을 미치지 않는 것으로 나타났다. (2) 심리적 주인의식은 직무만족과 직무성과 모두 유의한 영향을 미치는 것으로 나타났고, (3) 긍정심리자본의 희망과 낙관주의는 직무만족에 유의한 영향을 미치는 것으로 나타난 반면, 자기효능감과 복원력은 직무만족에 영향을 미치지 않는 것으로 나타났다. (4) 긍정심리자본의 낙관주의는 직무성과에 유의한 영향을 미치는 것으로 나타났으며, 자기효능감과 희망, 복원력은 영향을 미치지 않는 것으로 나타났다. (5) 심리적 주인의식은 긍정심리자본의 자기효능감, 희망, 낙관주의와 직무만족 및 직무성과 간의 관계에서 매개역할을 수행하는 것으로 나타났으나, 복원력과 직무만족 및 직무성과 간의 관계에서 심리적 주인의식은 매개역할을 수행하지 않는 것으로 나타났다. 이상의 연구결과는 조직운영의 효율성 개선을 위하여 과거에는 간과하였던 조직구성원 개인의 심리적‧정서적 요인의 중요성을 인지하고자 한다. 아울러, 조직은 인적자원의 심리적 강점을 활용하여 조직의 효율성 향상에 기여할 수 있도록 지속적인 프로그램 개발과 훈련이 다각도로 필요함을 시사하고 있다.
The PCKS-Machine: an Abstract Machine for Sound Evaluation of Parallel Functional Programs with First-Class Continuations

Field: Computer Science (Physical Sciences)

Abstract. The PCKS-machine is an abstract machine that evaluates parallel functional programs with first-class continuations. Parallelism is introduced by the construct pcall, which provides a fork-and-join type of parallelism. To the best of our knowledge, the PCKS-machine is the first implementation of such a language that is proved to have a transparent construct for parallelism: every program using such a construct returns the same result as in the absence of this construct. This machine is also characterised by the non-speculative invocation of continuations whose interest is illustrated in an application.
Plant Rabs and the role in fruit ripening

Field: Agricultural and Biological Sciences (Life Sciences)

Fruit ripening is a complex developmental process that involves the synthesis and modification of the cell wall leading up to the formation of an edible fruit. During the period of fruit ripening, new cell wall polymers and enzymes are synthesized and trafficked to the apoplast. Vesicle trafficking has been shown to play a key role in facilitating the synthesis and modification of cell walls in fruits. Through reverse genetics and gene expression studies, the importance of Rab guanosine triphosphatases (GTPases) as integral regulators of vesicle trafficking to the cell wall has been revealed. It has been a decade since a rich literature on the involvement of Rab GTPase in ripening was published. Therefore, this review sets out to summarize the progress in studies on the pivotal roles of Rab GTPases in fruit development and sheds light on new approaches that could be adopted in the fields of postharvest biology and fruit-ripening research.
Insecticidal Activities ofOcimum canumSims Essential Oil on TermitesMacrotermes subhyalinusRambur (Isoptera: Termitidae)

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract:The essential oil from the aerial parts of Ocimum canum grown in Togo was extracted by steam distillation. An analysis using Gas Chromatography (GC) and Gas Chromatography-Mass spectrometry (GC-MS) was carried to determine the oil percentage composition and to investigate its in vitro anti-termite activity by inhalation method. The extracted oil contained mainly terpineol-4 (39.40 %), linalool (23.80 %), γ-terpinene (6.70 %), (E)-α-bergamotene (6.20 %) and β-caryophyllene (5.30 %). The in vitro anti-termite activity of the volatile oil and its major components revealed an insecticidal activities on the termite species Macrotermes subhyalinus. At 1 µ.L-1 concentration the extracted oil caused a 100 % mortality of all individuals after 24 hours of exposure. The concentrations of 0.6 and 0.8 µl.L-1 respectively. Terpineol-4 and linalool also caused 100 % mortality after an exposure time of 24 hours. To compare with the commercial pesticide (Dursban) used as positive standard control, just a concentration of 0.6 µl.L-1 was necessary to kill 100 % of the tested termites after an exposure time of 24 hours. Terpineol-4 presented the weakest LD of 0.0628 µl.L-1 compared to Dursban:0.2472 µl.L-1; linalool: 0.2993 µl.L-1 and O. canum oil: 0.4004 µl.L-1. These findings indicated that the tested essential oil and its major components are a potential anti-termite alternatives to synthetic chemical pesticide in the termite control.Key words: Essential oilOcimum canumMacrotermes subhyalinusinsecticide
Some observations of temperature fluctuations in the coastal region of the Baltic

Field: Earth and Planetary Sciences (Physical Sciences)

Two months of almost daily observations of temperature variations on a section through the coastal region of the Baltic are presented. The results are found to be compatible with theoretical expectations (Walin, 1972; Csanady, 1968). In particular, we have observed large amplitude temperature variations confined within a region extending 5–10 km from the coast. Although this is not finally proved, these perturbations seem to propagate as internal Kelvin waves along the coast.
The Impact of the Covid 19 Pandemic on the Intrinsic and Extrinsic Motivation of The Panel Futsal Club During Covid-19 Pandemic

Field: Psychology (Social Sciences)

Motivation has a vital role in sport.In March 2020, WHO (World Health Organization) declared that covid 19 was a pandemic because all citizens have the potential to catch the virus.The purpose of this study was to assess and know the level of intrinsic and extrinsic motivation of futsal athletes from the panel futsal club of Sumenep in the middle of the pandemic of covid 19.Descriptive quantitative was used as the method of this research.The target of this research was the futsal athletes from the panel futsal club of Sumenep.Purposive sampling was used as the sampling technique.There were 30 participants of this research with the age range between 15-23 years.Data collection techniques of this research used the questionnaire.Then, for data analysis techniques used descriptive analysis was used.The result of this research showed that in the middle of the pandemic of covid 19, the level of intrinsic and extrinsic motivation of the futsal athletes from the panel futsal club was 46,66% which is categorized as medium.Therefore, it can be concluded that the covid 19 pandemics was bringing an impact to the athlete's level of motivation in practicing at the panel futsal club in Sumenep.
Improvement of Dynamic Respiration Monitoring Through Sensor Fusion of Accelerometer and Gyro-sensor

Field: Engineering (Physical Sciences)

In this paper, we suggest a method to improve the fusion of an accelerometer and gyro sensor by using a Kalman filter to produce a more high-quality respiration signal to supplement the weakness of using a single accelerometer. To evaluate our proposed algorithm's performance, we developed a chest belt-type module. We performed experiments consisting of aerobic exercise and muscular exercises with 10 subjects. We compared the derived respiration signal from the accelerometer with that from our algorithm using the standard respiration signal from the piezoelectric sensor in the time and frequency domains during the aerobic and muscular exercises. We also analyzed the time delay to verify the synchronization between the output and standard signals. We confirmed that our algorithm improved the respiratory rate's detection accuracy by 4.6% and 9.54% for the treadmill and leg press, respectively, which are dynamic. We also confirmed a small time delay of about 0.638 s on average. We determined that real-time monitoring of the respiration signal is possible. In conclusion, our suggested algorithm can acquire a more high-quality respiration signal in a dynamic exercise environment away from a limited static environment to provide safer and more effective exercises and improve exercise sustainability.
IDDF2024-ABS-0222 miR-4659a-3p promotes the proliferation of colon cancer mediated by 3-oxoacyl-ACP synthase (OXSM)

Field: Medicine (Health Sciences)

Background

3-oxoacyl-ACP synthase (OXSM) is a key enzyme in the mitochondrial fatty acid synthesis pathway, playing a role in the biosynthesis of lipoic acid as well as long-chain fatty acids required for mitochondrial function. Recent studies have shown that OXSM is involved in the progression of various tumors, but its role in colon cancer tumorigenesis remains to be investigated. The aim of this study is to investigate the function and underlying mechanism of OXSM in colon cancer.

Methods

Tissue microarrays and immunohistochemistry are used to analyze OXSM expression and its correlation with clinicopathological parameters. The upstream microRNA is identified by SmallRNA-seq and bioinformatics analyses. Cell growth and cell migration are measured in HCT116 cells simultaneously depleted of microRNA and OXSM. The RNA-seq is adopted to determine the signaling pathway of OXSM. The mouse xenograft assay is studied to confirm the role of OXSM in vivo.

Results

In this study, we find that OXSM level is significantly low in colon cancer patients, and low OXSM expression correlates with poor patient survival in colon cancer. The SmallRNA-seq analysis and biofunctional tests reveal that miR-4659a-3p is a novel microRNA of OXSM. Depletion of OXSM leads to the promotion of cell proliferation and migration in colon cancer, while simultaneously downregulation of miR-4659a-3p rescues the promotive phenomenon in cells ablated with OXSM. RNA-seq result shows that OXSM mediated the regulation of cytokine and chemokine biosynthesis and metabolism, including EGR1, HMOX1, ZFP36, TLR3, IL1RAP, TLR1, IFIH1, P2RX7. Moreover, OXSM depletion nude mice exhibit decreased level of cytokine and chemokine in tumor tissues and are more prone to tumorigenesis. Conclusions miR-4659a-3p promotes the formation of colon cancer by inhibiting cytokine and chemokine biosynthesis and metabolism via OXSM, providing a potential target for colon cancer diagnosis and therapy.
Cuneiform Tablet 1913.14.1679, Spurlock 1913.14.1679

Field: Arts and Humanities (Social Sciences)

[Text Description:] Document concerning measures of barley ❧ [Text or Publication Number Note:] Spurlock 1913.14.1679; CDLI P421530 ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Yellowish White (10YR 9/2) Moderate Yellowish Pink (5YR 7/4) ❧ [Physical Object Note:] 4.7 x 3.7 x 1.7 cm (28 g)
The Role of Firearms in the Songye Region (1869–1960)

Field: Social Sciences (Social Sciences)

In the nineteenth century, Central Africa in general, and the Songye region in particular, was located between two groups of arms traffickers. In the second half of the nineteenth century, the Songye region was invaded by Arab-Swahili traffickers. These traffickers, acting under Tippu Tip whose headquarters was in Kasongo on the Lualaba, sent armed gangs into the Songye region to look for slaves and ivory. According to Nestor Kapenga, Lumpungu was not the one in possession of firearms. Many Songye chiefs, in order to escape from the attacks, allied themselves with the Arab-Swahili traffickers and became themselves hunters for slaves and ivory. In return they were given firearms and gun powder in order to carry out their work. Many Songye recognised the provenance of firearms from the west, through the Tshokwe, but oral testimonies allude to a war that Lumpungu and Ngongo Leteta waged against a Tshokwe chief called Kelendende. Keywords: Arab-Swahili traffickers; Central Africa; Firearms; Kasongo; Lualaba; Lumpungu; Songye Region
Analysis, Design, and Control of Hopping Robot

Field: Engineering (Physical Sciences)

The control of dynamically stable legged locomotion has made great strides in the past decade. Usually powerful hydraulic actuators are harnessed for control of the legged robot. In this report, we focus on a planar one-legged hopper, which is electrically actuated. This type of actuation technology is clean, safe and cheap, suitable for indoor use and autonomous robots. However, because DC motors have much smaller torque/mass ratio than hydraulic actuators, special consideration must be paid to the modelling, design and control of the hopper. For the vertical hopper we derived a dynamical model including actuator dynamics, and developed different control strategies based on the total energy of the system. These strategies are verified by simulation. For planar motion we used the passive dynamics concept to model the hopper. This modelling leads to an energy efficient system, and might simplify the control. A one-legged hopper was designed and constructed, and some of the control alg...
ELECTRON BEAM SENSITIVITY AND STRUCTURE OF THE GLASSY PHASE OF CERAMICS

Field: Materials Science (Physical Sciences)

The electron beam sensitivity of glassy ceramics was reviewed. It was shown that the glassy phase resulting from the segregation of additives such as CaO or MgO at the grain boundaries was highly sensitive to the electron beam. We have reported elsewhere that the electron damage kinetics corresponds to an ionization process (Laval, Westmacott, 1979). This ionization process was discussed in terms of chemical bondings and ionic states, and by referring to the soda-glass structure. From these considerations new insights into the structure of the glassy phase were obtained. From the nature of the ionization effects it is possible to postulate which ion will lead to the damage and therefore to know the structure and the composition of the glassy phase on a nanometric scale. Thus the electron beam sensitivity of glassy ceramic enables a very thin intergranular glassy phase to be characterized and is of great value in determining the structure of the grain boundaries and of metal-oxide or glass-ceramic interfaces.
High-accuracy and high-efficiency fringe projection profilometry

Field: Engineering (Physical Sciences)

Fringe Projection Profilometry (FPP) system consists of four main measurement stages: calibration, phase measurement, correspondence, and reconstruction, each designed to solve some specific problems in the system. In this report, a comprehensive guide of how-to setup and use the FPP system is descripted, including new software developed for enhanced performance. One method was suggested to improve the accuracy during the calibration stage, by integrating the subpixel edge detection. This method was shown to be able to achieve higher accuracy than the traditional method in detecting the center of the circle. A phase unwrapping method was proposed to improve the efficiency in phase measurement stage, by generating an additional staggered wrapped phase from the original wrapped phase and divide the period of fringe order into two parts. The proposed method demonstrated improved performance and robustness compared to the Tri-PU Method.
Mapping of quantitative trait loci for thermosensitive genic male sterility in indica rice

Field: Agricultural and Biological Sciences (Life Sciences)

The objective of this work was to select and use microsatellite markers, to map genomic regions associated with the genetic control of thermosensitive genic male sterility (TGMS) in rice. An F2 population, derived from the cross between fertile and TGMS indica lines, was used to construct a microsatellite-based genetic map of rice. The TGMS phenotype showed a continuous variation in the segregant population. A low level of segregation distortion was detected in the F2 (14.65%), whose cause was found to be zygotic selection. There was no evidence suggesting a cause-effect relationship between zygotic selection and the control of TGMS in this cross. A linkage map comprising 1,213.3 cM was constructed based on the segregation data of the F2 population. Ninety-five out of 116 microsatellite polymorphic markers were assembled into 11 linkage groups, with an average of 12.77 cM between two adjacent marker loci. The phenotypic and genotypic data allowed for the identification of three new quantitative trait loci (QTL) for thermosensitive genic male sterility in indica rice. Two of the QTL were mapped on chromosomes that, so far, have not been associated with the genetic control of the TGMS trait (chromosomes 1 and 12). The third QTL was mapped on chromosome 7, where a TGMS locus (tms2) has recently been mapped. Allelic tests will have to be developed, in order to clarify if the two regions are the same or not.
An Integrated Framework for Analysis and Prediction of Impact of Single Nucleotide Polymorphism Associated with Human Diseases

Field: Computer Science (Physical Sciences)

Single nucleotide polymorphisms are most common type of genetic variation in human genome. Analyzing genetic variants can help us better understand the genetic basis of diseases and develop predictive models which are useful to identify individuals who are at increased risk for certain diseases. Several SNP analysis tools have already been developed. For running these tools, the user needs to collect data from various databases. Secondly, often researchers have to use multiple variant analysis tools for cross validating their results and increase confidence in their findings. Extracting data from multiple databases and running multiple tools at a time, increases complexity and time required for analysis. There are some web-based tools that integrate multiple genetic variant databases and provide variant annotations for a few tools. These approaches have some limitations such as retrieving annotation information, filtering common pathogenic variants. The proposed web-based tool, namely IPSNP: An Integrated Platform for Predicting Impact of SNPs is written in Django which is a python-based framework. It uses RESTful API of MyVariant.info to extract annotation information of variants associated with a given gene, rsID, HGVS format variants specified in a VCF file for 29 tools. The results are in the form of a CSV file of predictions (1) derived from the consensus decision, (2) a file having annotations for the variants associated with the given gene, (3) a file showing variants declared as pathogenic commonly by the selected tools, and (4) a CSV file containing chromosome coordinates based on GRCh37 and GRCh38 genome assemblies, rsIDs and proteomic data, so that users may use tools of their choice and avoiding manual parameter collection for each tool. IPSNP is a valuable resource for researchers and clinicians and it can help to save time and effort in discovering the novel disease-associated variants and the development of personalized treatments.
New Distillation Packing

Field: Chemical Engineering (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew Distillation PackingM. R. CannonCite this: Ind. Eng. Chem. 1949, 41, 9, 1953–1955Publication Date (Print):September 1, 1949Publication History Published online1 May 2002Published inissue 1 September 1949https://doi.org/10.1021/ie50477a028RIGHTS & PERMISSIONSArticle Views95Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (499 KB) Get e-Alerts