jimnoneill/paper-to-field-training huggingface dataset:
On Efficient Utilization of Training Pilots for Linear Equalization of QAM Transmissions

Field: Computer Science (Physical Sciences)

Conventional approaches to linear equalization of data transmissions under frequency selective channels simply treat the problem as a system identification issue. However, practical data communication systems impose additional conditions on the channel input signals such as LDPC error correction coding and known data constellation. We study a unified framework to integrate these known constraints into the channel equalization procedure and propose a linear programming-based approach to channel equalization for QAM signals that can succeed with significantly reduced pilots. In addition to utilizing the information of QAM constellation, our method exploits the code information of LDPC forward error correction coding to improve the equalization performance and convergence properties.
Catalytic Enantioselective Addition of Dialkylzinc to N-Diphenylphosphinoylimines. A Practical Synthesis of α-Chiral Amines

Field: Chemistry (Physical Sciences)

The enantioselective addition of dialkylzinc reagents to N-diphenylphosphinoylimines derived from aryl-, furyl-, and cyclopropylaldehydes is efficiently catalyzed by a copper(II) triflate/(R,R)-MeDUPHOS complex. The yields are high (51-98%), and the enantiomeric excesses vary from 85 to 96%. This route provides a practical route to alpha-chiral amines.
Two-dimensional fine particle positioning under an optical microscope using a piezoresistive cantilever as a manipulator

Field: Computer Science (Physical Sciences)

Brill profit levels and organic growth in line with expectations, integration V&R according to plan and continuation of eBusiness growth Update on year-to-date performance During the third quarter Brill's eBusiness continued its strong growth, driven by eBooks and digital primary sources.This growth compensated for the ongoing decline in print books.YTD Journal sales declined mainly due to delayed invoicing, which is expected to be recovered in Q4, and continuing IT problems at our UK based distributor.Overall Brill's revenues including the acquisition of Vandenhoeck & Ruprecht and Böhlau Verlag (V&R) are clearly ahead of last year.Cost of goods sold improved slightly as a result of the migration from print to eBooks.Operating costs were in line with expectations.Year to date EBITDA, operating profit and net profit have developed as planned.The integration of V&R runs according to plan.Both the Brill as well as the V&R teams and staff are now part of one global matrix organization.Various integration projects in IT, production, distribution, publishing and sales are underway.Management closely leads and monitors the integration and is pleased with the progress and the results of the acquired V&R business so far.In August, Brill acquired the journal Folia Primatologica from Karger Publishing, an important addition to our Biology portfolio.At the end of Q3 Brill's Book Archive was launched, a digital archive expanding our eBook list with more than 6,000 back list titles in 2021.The first sales are expected in Q4. FY OutlookThe COVID-19 pandemic continues to make market circumstances difficult and unpredictable.In Asia important countries are still in lockdown and (intercontinental) travel is still difficult or impossible, limiting our staff to visit authors, conferences and customers in person.The shortages in the global supply chains are hampering Brill as well, to the extent that this may have a negative impact on the results of the important 4 th quarter and could affect our top-and bottom line negatively.
Benign vaginal rhabdomyoma.A light and electron microscopic study

Field: Medicine (Health Sciences)

A benign vaginal rhabdomyoma from a 49-year-old woman was examined by light and electron microscopy. While many of the ultrastructural features conformed to those noted in previously described rhabdomyomas, certain features are described for the first time. These include attachment plaques between cells enclosed within a common basement membrane, cytoplasmic bodies, and peripheral couplings. Finally, the literature is reviewed and the reported cases of rhabdomyoma are divided into adult and fetal types based upon light microscopic criteria.
Phosphorothioate Antisense Oligonucleotides Bind P-Body Proteins and Mediate P-Body Assembly

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Antisense oligonucleotides (ASOs) regulate gene expression by binding to complementary target RNA, and ASOs can be designed to take advantage of a growing array of post RNA binding molecular mechanisms. Intracellular trafficking of ASOs influences their efficacy. We have identified a number of membrane-less structures in the nucleus, nucleolus, and cytoplasm where phosphorothioate-modified ASOs (PS-ASOs) accumulate and have shown that PS-ASOs can induce the formation of new nuclear structures such as PS-bodies and paraspeckle-like structures. In this study, we report that PS-ASOs can localize to cytoplasmic processing bodies (P-bodies) and increase the number of P-bodies in cells. The antisense activity of PS-ASOs was not affected by the absence of essential P-body assembly proteins DDX6 and LSm14A. Moreover, the effects of PS-ASOs on P-body assembly were independent of their antisense activities. The phosphorothioate modification stabilizes the association between ASOs and cellular proteins and is essential for the P-body localization of ASOs. Since PS-ASOs bind to major P-body components, PS-ASOs may serve as scaffolds for P-body formation. Taken together, these results indicate that interactions of PS-ASO with proteins, rather than antisense activities, are essential for the dynamic interplay between PS-ASOs and P-bodies.
(200 follower special - read description!) [Aftergore I] SPEICIDE

Field: Arts and Humanities (Social Sciences)

Toadie and Slick if you've been reading this, I'm just archiving this song just in case it gets taken down. I have no intentions to reupload it and leech off your fame. Original description: *y’know, i used to know a kid who looked a lot like you. *because of them, i had hope that maybe after all this time… *…things would finally look up. *... *guess that’s on me, huh? Aftergore Discord: discord.gg/WbzykND ====== BEHIND THE SCENES ====== After 200 followers and 55 tracks, this account finally gets its first Megalo. First off, the sick new thumbnail is by @ shinyemerrald , and the Aftergore logo is by @ repeatsc and Toadie Thanks as always to them for their wonderful work. “SO WHAT’S WITH THE NAME?” I hear you ask. “Speicide” isn’t a word, but rather a pseudo-word made up of Latin roots. 6 years of education put to good use, amiright? All the “-cide” words originate from Latin roots, with “sui” relating to self, “geno” relating to group, “matri” relating to mother, “regi” relating to king, et cetera. “spes” is the Latin word for hope. So “speicide” would literally mean “the killing of hope.” Humanity gave the Underground a glimmer of hope for once, only for it to be violently snatched away from them. This took some inspiration from the first version of Our Broken Constellations, as that Megalo manages to be an intense fight theme while also capturing a more somber mood. ====== 200 FOLLOWERS? EXCUUUUUSE ME? ====== I don’t know what to say, really. I wasn’t sure we’d ever get here, but I’m happy we did. I think people are quick to rag on the community for being Megalo-centric, and while Toadie and I both think it is a bit much, I think it’s really a testament to the unsung greatness of this community that this account amassed 200 followers without a single Megalo. Don’t forget that, any of you. You don’t need to be the next Drop or churn out stuff you hate to gain a following. It’s all about patience and persistence. Staying determined, that’s what Undertale taught us best, eh? Thank you to all of you for following this initially experimental account. I’m so honored, and I know Toadie is too. We’ll continue to make content for you to enjoy, and even though we finally posted a Megalo, it doesn’t mean this’ll happen super often. We treat Megalovania like any other track, we just wanted to wait this long to finally upload one. So stay tuned, I’m pretty sure you’ll like what’s coming down the pipeline. And most importantly, thank you above all to @ dashingtoadie-the-sequel , for being a blessing to this community and a constant joy to work with. You are without a doubt my best friend in this community, and the true hero of this account. I love ya, ya wonderful void person. Viva la Surviv— wait, wrong account -Slick
Secreted Protein Acidic and Rich in Cysteine (Sparc) KO Leads to an Accelerated Ageing Phenotype Which Is Improved by Exercise Whereas SPARC Overexpression Mimics Exercise Effects in Mice

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein implicated in various functions, including metabolism, tissue regeneration, and functional homeostasis. SPARC/Sparc declines with ageing but increases with exercise. We aim to verify two hypotheses: (1) SPARC deficiency leads to an ageing-like phenotype (metabolic decline, muscle loss, etc.), and (2) SPARC overexpression would mimic exercise, counteract ageing, and improve age-related changes. Our mice experiments are divided into two parts. First, we explore the consequences of Sparc knockout (KO) and compare them to the ageing effects. We also observe the effects of exercise. In the second part, we study the effects of SPARC overexpression and compare them to the exercise benefits. At the end, we make an analysis of the results to point out the analogies between Sparc KO and the ageing-like phenotype on the one hand and make comparisons between SPARC overexpression and exercise in the context of exercise counteracting ageing. The measurements were mainly related to tissue weights, adiposity, metabolism, and muscle strength. The main findings are that Sparc KO reduced glucose tolerance, muscle glucose transporter expression, and abdominal adipose tissue weight but increased glycogen content in the muscle. SPARC overexpression increased muscle strength, muscle mass, and expressions of the muscle glucose transporter and mitochondrial oxidative phosphorylation but lowered the glycemia and the adiposity, especially in males. Collectively, these findings, and the data we have previously reported, show that Sparc KO mice manifest an ageing-like phenotype, whereas SPARC overexpression and exercise generate similar benefits. The benefits are towards counteracting both the SPARC deficiency-induced ageing-like phenotype as well as reversing the age-related changes. The potential applications of these findings are to build/optimize Sparc KO-based animal models of various health conditions and, on the other hand, to develop therapies based on introducing SPARC or targeting SPARC-related pathways to mimic exercise against age-related and metabolic disorders.
Study of the dielectric properties of HFO gas, and its application to reduce the environmental impact of medium-voltage systems

Field: Energy (Physical Sciences)

Le remplacement du SF6 dans les appareils électriques est au centre des préoccupations de l’industrie électrique depuis des années. En effet, le SF6 est le gaz présentant le pouvoir de réchauffement climatique le plus élevée connu. Depuis de nombreuse années des alternatives au SF6 sont étudiées sans succès. Les hydrofluorooléfines présentent de bonne aptitudes pour substituer le SF6 dans les systèmes isolés au gaz en moyenne tension.Dans ce contexte, des études préliminaires ont révélé le potentiel du HFO-1234ze(E) en tant que gaz isolant pour de l’appareillages moyenne tension. L’objectif de ce travail est de générer des données et des connaissances pour le dimensionnement d’appareils moyenne tensions avec du HFO-1234ze(E). Les résultats expérimentaux incluent des mesures de tensions de claquage obtenues dans diverses conditions de tension (DC, choc impulsionnel), de pression (de 1 à 3 bar), de distance inter-électrode (10 à 100 mm), et de forme d’électrodes. Cette large gamme de configurations a permis de mettre en évidence deux modes de claquage bien distincts et comparable à ceux présents dans le SF6. Quand le champ est fortement inhomogène, géométrie la plus critique pour les appareils électriques, le claquage est « contrôlé par la propagation » de leaders. Les leaders se propagent dans l’espace inter-électrodes par sauts à des vitesses de l’ordre de 106 m/s sans nécessairement conduire au claquage. Quand le champ devient plu homogène, le claquage devient « contrôlé par l’initiation ». Quand une pré-décharge s’initie, elle conduit systématiquement au claquage. La pression joue un rôle important sur la tension d’initiation contrairement à la tension de claquage. En fin, l’un des résultats importants de ces travaux est la mise en évidence de l’influence complexe entre la dégradation du HFO, la présence de particules solide à la surface de l’électrode et la perte de tenue diélectrique en champ quasi-homogène après un seul claquage.
Korean Contributions to Agriculture, Technology, and State Formation in Japan: Archaeology and History of an Epochal Thousand Years, 400 B.C.–A.D. 600

Field: Arts and Humanities (Social Sciences)

This is a study of Korean contributions to cultural changes in ancient Japan as it developed agriculture and increasing social complexity and finally formed the Yamato state over the course of a thousand years, between 400 b.c. and a.d. 600. Central to this study are three broad themes, supported primarily by archaeology but importantly informed by historical texts. First, key cultural features and technologies that were essential to increasing social complexity in Yayoi period Japan and to formation of a centralized state in the sixth century a.d. entered the archipelago directly from the Korea Peninsula. Second, a dominant factor behind the infusion of Korean cultural features was the movement, in several waves, of peninsula residents into the Japanese archipelago. While trade moved peninsula goods to the archipelago all throughout the formative period, Korean technologies, skills, ideologies, and cultural systems moved with people, including permanent immigrants, temporary residents, and official envoys. The Korean immigrants in particular were impelled initially by explosive population growth in Korea fueled by the spread of agriculture there and later by increasingly tumultuous political and military events that unfolded in the peninsula as rival polities contended for power during several hundred years of war. Third, a number of Korean immigrants emerged as powerful technocrats and political functionaries during the Kofun period, providing important organizational experience and service to the Yamato court during the process of state formation in Japan.
Adherencia de los profesionales al protocolo de manejo y red de apoyo familiar de sífilis gestacional y congénita

Field: Health Professions (Health Sciences)

Objective: To determine the adherence of medical and nursing professionals to\nthe protocol of congenital syphilis and gestational implemented by the Ministry\nfor the Protection. Materials and Methods: Descriptive longitudinal study with\n215 pregnant population and sample 11 pregnant women diagnosed with gestationalsyphilis\nin 10 localities of a state in Colombia between February and April 2013 were used as\ninstruments the“Familiograma”, Faces III (Olson) protocol check list. Measures of central\ntendency.Voluntary participation underinformed consent. Results: Population average is 20\nyears,low education, housewives,married,they have socialsecurity.60% ofnuclear families,\nfacesIII:50%balanced families,30%moderate and 20%extreme.Protocol:One (1)pregnant\nwomen had no prenatal care. 54.5% reported no risk factors, diagnostic 60.3% in third\nquarter, 36.3% newborns with congenital syphilis, no serological monitoring is recorded, no\neducational record to the patient or partner, no valuation genital skin or physical\nexamination of pregnant women, newborns incomplete care, provided proper\ntreatment. Conclusions: Prevalence of nuclear and balanced families, with ability to learn\nfrom crises. No full adherence to the protocol, no monitoring by professionals providing care\nand attention to the user. Lack of continuing education about the topic to the nurse as leader\nof the process in the region is evident.
Aggressiveness index of Apis Mellifera (Hymenoptera: Aapidae)

Field: Agricultural and Biological Sciences (Life Sciences)

An index measuring the aggressiveness among ten colonies of Apis mellifera was elaborated based on the third generation synthetic indices by Charum et al. (1999). The index values are subject to a fixed parameter used as the beginning or standard value, and correspond to the aggressive features of some Africans colonies studied by Rothenbuler et al. (1968). In the ten colonies the index values are notably smaller than those of African colonies and are biased to the lowest values. This indicates, that neither of the colonies presents an extreme aggressive behavior and it is possible that they have not Africans genotypes. These results are an indirect proof of the index. Nevertheless, it could be improved by the introduction of other factors such as, climate and colony management.
Machine-learning modelling of tensile force in anchored geomembrane liners

Field: Engineering (Physical Sciences)

Geomembrane (GM) liners anchored in the trenches of municipal solid waste (MSW) landfills undergo pull-out failure when the applied tensile stresses exceed the ultimate strength of the liner. The present study estimates the tensile strength of GM liner against pull-out failure from anchorage with the help of machine-learning (ML) techniques. Five ML models, namely multilayer perceptron (MLP), extreme gradient boosting (XGB), support vector regression (SVR), random forest (RF) and locally weighted regression (LWR) were employed in this work. The effect of anchorage geometry, soil density and interface friction were studied with regards to the tensile strength of the GM. In this study, 1520 samples of soil–GM interface friction were used. The ML models were trained and tested with 90% and 10% of data, respectively. The performance of ML models was statistically examined using the coefficients of determination (R 2 , R 2 adj ) and mean square errors (MSE, RMSE). In addition, an external validation model and K-fold cross-validation techniques were used to check the models’ performance and accuracy. Among the chosen ML models, MLP was found to be superior in accurately predicting the tensile strength of GM liner. The developed methodology is useful for tensile strength estimation and can be beneficially employed in landfill design.
ANALISA KEKUATAN KONSTRUKSI BRACKET TOWING HOOK PADA TB. BONTANG DENGAN METODE ELEMEN HINGGA DAN RULES BKI

Field: Engineering (Physical Sciences)

Bracket towing hook construction planning is to make a construction that has the stress level of the allowable limit and can be accepted by the construction. Requirements for towing hook are structural strength if the stress levels that occur below the elastic region. By calculating the value of the maximum load, maximum stress, von mises stress and deflection (displasment) that occur in the construction of bracket towing hook, so that known security level of construction that has been designed. Research on construction of the strength bracket towing hook need to be considered and carried out, where the stress caused by load about them should not exceed the maximum limit σyield materials and σallow based on the rules from the class. The reference to rules used in this research is based on the rules of Bureau Classification Indonesia. Analysis of the strength bracket towing hook construction is done by using finite element methode. The analysis used is a static load analysis to determine the characteristics and location of greatest stress on the construction bracket towing hook based on three variations of loading. Analysis results obtained using finite element methode based program of greatest stress maximum occurs in the condition of the bracket towing hook with maximum horse power load that is equal to 44,2 N/mm2 where the most critical area occurs at node 457 which is located at frame number 23 lengthwise section and stiffener number 7 cross section. This stress is still in a safe condition because after compared with material σyield of 400 N/mm2 and σallow based BKI rules of 178,12 N/mm2 produce safety factor value of 9,05 and 4,03
Role of Hepatocyte Nuclear Factor 4α in Regulating Hepatic Differentiation and the Inflammatory Response in HCC

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract: Limited treatment options are available for hepatocellular carcinoma (HCC), especially in the advanced stage, which is associated with a poor prognosis. Many studies have demonstrated that hepatocyte nuclear factor 4α (HNF 4α) plays an important role in hepatic differentiation and the carcinogenesis of HCC. HNF 4α critically regulates hepatic differentiation by controlling a large number of genes involved in hepatic functions including metabolism, xenobiotic detoxification, bile acid synthesis, and serum protein production. It has also been confirmed to play an important role in the inflammatory environment in HCC. Thus, HNF 4α is considered to be a promising target for the treatment of HCC. Some studies have demonstrated that regulating HNF 4α expression in HCC had beneficial effects in in vivo and in vitro experiments. We herein review the role of HNF 4α in regulating hepatic metabolism and the inflammatory response, aiming to provide some ideas on induced hepatic differentiation therapy and regulating the inflammatory microenvironment for the treatment of advanced HCC.
Primer Design and Sequence Information for Complete Mitochondrial ND5 Gene in the Black and White Lines of Silky Fowl (Gallus gallus)

Field: Agricultural and Biological Sciences (Life Sciences)

In order to reveal the NADH dehydrogenase subunit 5 (ND5) gene conformation of the Silky fowl, I designed 11 primers and sequenced the entire ND5 gene nucleotide sequences in the Black and White lines of Silky fowl, and compared it with that of White Leghorn chicken. The same nucleotide sequences were observed at ND5 gene region in the Black and White lines. The Silky fowl ND5 gene was transcribed from the H-strand of mitochondria DNA, consisted of 1, 818 by nucleotides (564A, 636C, 194G, and 424T) with no deletion and insertion, and encoded for a 605 amino acid protein. ND5 gene connected ND4 gene via three transfer RNA genes, tRNA (His), tRNA (Ser), and tRNA (Leu), at the 5' end, whereas at the 3' end it connected with a nucleotide sequence ACTA which is adjacent to cytochrome b (Cyt b) gene. Homologies of ND5 gene nucleotide sequences and amino acid sequences between the Silky fowl and White Leghorn chicken were 99.7% and 99.3%, respectively. The nucleotide sequence data reported in this article will appear in the EMBL, GenBank, and DDBJ nucleotide sequence data base under the accession number AF142407.