jimnoneill/paper-to-field-training huggingface dataset:
>b<Comparison of estradiol benzoate doses at beginning of the synchronization and early resynchronization of ovulation for timed- insemination in >i<Bos indicus>/i< beef cows>/b<

Field: Veterinary (Health Sciences)

\n Based on the wide use of estradiol benzoate (EB) in timed-AI (TAI) protocols, with this research we aimed to compare the effect of different doses of EB in synchronization of ovulation and resynchronization at 14 days after TAI in suckled Nelore beef cows. Therefore, this dissertation consists of two studies. In the first study we compared three EB doses (1 mg, n&#61; 20; 1.5 mg, n&#61; 15; and 2 mg, n&#61; 21) associated with a progesterone device (P4) at the beginning of a synchronization protocol for TAI in primiparous (n&#61; 20) and multiparous (n&#61; 36) beef cows. Follicular wave emergence (FWE) did not differ (P &#62; 0.05) among treatment groups, as well as the other features. The FWE occurred later (P &#60; 0.05) in primiparous cows than in multiparous cows. In addition, the follicular diameter of primiparous was smaller (P &#60; 0.05) than multiparous cows at D 2 and TAI. We conclude with this study that doses from 1 to 2 mg EB were efficient in promoting the emergence of the new follicular wave. Furthermore, we also concluded that the delay in follicular emergence in primiparous cows contributed to the reduced follicular diameter at TAI compared to multiparous cows. In the second study, we compared the use of 1 or 2 mg EB associated with a P4 device at the beginning of the resynchronization protocol at 14 days post-TAI in suckled Bos indicus beef cows (1 mg; EB-1 group, n&#61; 516; and 2mg, EB-2 group, n&#61; 510). On D14, along with the beginning of resynchronization, it was possible to assess the presence of an active corpus luteum in 933 cows. In addition, a subgroup of these cows (n&#61; 18-19/group) was submitted to daily ultrasound assessments from day 14 to 22 for localization and measurement of antral follicles and corpus luteum area, and assessment of corpus luteum perfusion. On D22, all cows were submitted to ultrasound evaluations in color Doppler mode to detect luteolysis. Cows with luteolysis detected on D22 were submitted to TAI2 on D24. The conventional diagnosis of pregnancy was performed 30-35 days after TAI1 or TAI2. The pregnancy per AI (P/AI) from first TAI was 21,4% greater (P&#60;0.05) in the EB-1 group than in the EB-2 group. The potential embryonic loss between D22 and D30- 35 was doubled (P&#60;0.05) in the EB-2 group. The P/AI of the second TAI did not differ (P&#62; 0.1) between groups. Thus, with satisfactory pregnancy rates in TAI 1 and TAI 2, the EB-1 group had a greater cumulative P/AI after two TAIs with a 24-day interval than the EB-2 group. Therefore, we can conclude that 1 mg EB is the safe and recommended dose to be used in association with the P4 device in resynchronization protocols started at 14 days after TAI.\n
Ramon Syndrome: A Rare Case of Cherubism with Gingival Fibromatosis in an Adult Female

Field: Dentistry (Health Sciences)

Abstract: Cherubism is a rare genetic disorder characterized by painless bilateral expansion of the mandible and maxilla. We present an unusual case of a 50-year-old female patient with Ramon syndrome, a rare variant of cherubism, accompanied by gingival fibromatosis. The patient exhibited symptoms of short stature, mental retardation, rheumatoid arthritis, epilepsy, hirsutism, and gingival enlargement. Clinical examination revealed generalized gingival inflammation with plaque and attachment loss. Radiographically, bilateral defined multilocular radiolucencies were observed in the mandibular body and ramus. The patient underwent a non-surgical phase, including oral hygiene motivation and periodontal debridement, followed by a surgical phase involving gingivoplasty and internal bevel gingivectomy with open flap debridement. Histopathological analysis confirmed the presence of fibroblasts, multinucleated giant cells, and fibrous connective tissue. The patient&#039;s son also presented with bilateral facial swelling and similar radiographic findings, indicating familial inheritance of cherubism. The case demonstrates the clinical, radiographic, and histopathological features of cherubism associated with gingival fibromatosis and highlights the challenges in diagnosis and management. Regular follow-up and maintenance are essential for long-term stability and prevention of recurrence. This report contributes to the limited literature on cherubism in older patients and emphasizes the importance of early identification and intervention in affected individuals.
A study of photodynamic therapy for intertumor laser irradiation methods using PP (Polipuropiren) tube

Field: Medicine (Health Sciences)

The purpose of this study is to evaluate the photodynamic therapy (PDT) by the intertumor movement type laser irradiation methods using the Polipuropiren type tube for the advanced cancer.Materials and Methods: The rabbit VX2carcinoma transplanted into the rabbit dorsal side of the foot. When the developing cancer reached up to the size of 32×20×20mm. A dose of 5mg/kg of the photosensitizer, a Hematoporphyrin derivative made by QUENTRON OPTICS company was administered intravenously. Immediately 24hours after administration, the polypropylene type tube was inserted into the tumor with the fiber inside which rotates with an irradiation condition of 18mm/min,12R. P. M.. A pulse repetition frequency of 80Hz and energy per pulse of 5mJ was applied consequently, along a tube with the tumor was 15J/mm.Results: The tumor around the tube was destroyed up to the extent of 28mm in diameter. We suggest that the PDT using the intertumor movement type laser irradiation methods is applicable for the treatment of advanced cancer.
CuO Nanoplate Array Supported on Ni foam, a Highly Active Catalyst in the Degradation of Rohdamine B with Hydrogen Peroxide

Field: Chemical Engineering (Physical Sciences)

Removal of organic pollutants from wastewater by catalytic degradation of those organics with hydrogen peroxide has been a hotspot in the field of water environmental protection. In this work, CuO nanoplatelet array supported on Ni foam has been prepared by a facile hydrothermal route. Degradation of Rhodamine B (RhB) with H2O2 catalyzed by the as-prepared CuO nanocatalyst was investigated. It is found that RhB can be effectively degraded by H2O2/CuO. The large H2O2 dosage and high reaction temperature is favourable for the fast degradation of RhB. In addition, the as-prepared CuO nanoplatelet array supported on Ni foam exhibits high stability and good reusability in the RhB degradation reaction.
MECHANISM OF THE HYPOCALCAEMIC ACTION OF PARENTERALLY ADMINISTERED MAGNESIUM

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

ABSTRACT Subcutaneous injection of 300 μmol magnesium raised the serum magnesium to 4.00 mmol/l after 30 min in 150 g male rats and reduced the serum calcium concentration by 0.17 mmol/l after 60 min. Magnesium also acutely diminished the serum concentration of 45 Ca given three weeks previously. The administration of magnesium did not reduce the serum concentration of 45 Ca and did not increase the rate of disappearance of 45 Ca from the serum, when subcutaneous or intravenous labelling took place 180–210 min before the magnesium injection. The magnesium-induced hypocalcaemia therefore cannot be explained by an increased removal of calcium from the circulation. The results are compatible with the hypothesis that the magnesium-induced hypocalcaemia is caused by the release of calcitonin. Injections of 300 μmol magnesium chloride at 12 h intervals for 72 h trebled the 24 h renal excretion of both 40 Ca and 45 Ca given three weeks previously. The 24 h renal excretion of hydroxyproline was unaltered. Thus there was no indication that the intermittent magnesium injections produced any long-term inhibition of the turnover of bone matrix and bone mineral.
Spatial Difference of Wind Erosion Intensity and Impact Analysis

Field: Environmental Science (Physical Sciences)

The tests for observing wind erosion in field show that there exists spatial difference of wind erosion intensity in Housan area of Inner Mongolia with rolling hills. This difference affects the spatial difference of soil texture, soil fertility and arable land biomass. Wind erosion gradually decreases from the top to the foot of hill. On the top of hill, wind erosion intensity is very high, soil bulk density very big, soil fertility low, and agricultural productivity also low. In the south slope of hill, wind erosion intensity is comparatively low, soil bulk density low, soil fertility very comparatively high, and agricultural productivity also high. In the north slope of hill, wind erosion is very serious, and soil fertility is low. Understanding this spatial different will provide scientific reference for synthetically ecological treatment.
The effects of drought on farm production in the Umniati area of Zimbabwe. A descriptive study.

Field: Agricultural and Biological Sciences (Life Sciences)

"Objectives: The overall objective of this paper is to document peasant farmers management response to drought conditions. The specific objectives are to: 1. Determine if crop mixes shifted from drought prone to drought resistant crops 2. Determine if crop yields varied as a result of the drought 3. Determine if farmers timed the planting of their crops in response to rainfall."--Page 7.
Recruitment of juvenile corals onto coral tables preyed upon by Acanthaster plana

Field: Environmental Science (Physical Sciences)

Corals of 3 table-forming species of the genus Acropora, whose tissues had been removed by the seastar Acanthasterplanci (L.) during 2 mo prior to a major annual coral-spawning season, acted as substrata onto which juvenile corals settled.Juvenile corals were detected microscopically in the laboratory on samples taken from tables 10 wk after spawning time (mean diameter of juveniles 1.3 mm; density 3.5 per 100 cm2).Previously it had been thought that a delay of at least 1 yr was necessary before corals would settle after predation by A. planci.The same tables were sampled again after the next coral-spawning season (1 yr later).Desplte the presence of algae and other colonizing organisms, new corals had settled at a density of 2.8 per 100 cm!About 34 41 of the previous year's juveniles had survived, and mean diameter of these was now 7.24 mm When tables were searched closely in the field, surviving juveniles and some new recruits (with diameters down to 2.00 mm) could be detected.These results indicate that apparent delay in settlement after predation by A. planci can be due to the small size of newly settled corals, which can only be seen by careful inspection of the substratum during the first year after settlement, and which do not achieve 3-dimensional structure until some time later.A. planci was still present at the slte when these observations were made.Thus re-establishment of the coral community on this reef had begun during the time that the adult community was being preyed upon.
PENGOBATAN TRADISIONAL JAWA DALAM MANUSKRIP SERAT PRIMBON JAMPI JAWI

Field: Arts and Humanities (Social Sciences)

AbstractThis study aims to describe Javanese traditional medical care in the Serat Primbon Jampi Jawi manuscript. It used the modern philology approach. The source of the researchdata was Serat Primbon Jampi Jawi Volume I, a collection of the Reksapustaka Library,Mangkunegaran, Surakarta. The research findings are as follows. First, Javanese traditionalmedical care is found for intestinal worms and dysentery (bloody stools). Second,the ingredients/medical prescriptions are in the form of: root (narcissus), wood/bark(sandalwood, kayu timur, and mesoyi), leaves (tamarind, lampes, and trawas), fruits (anise,chili, areca nut, and nutmeg), seeds (black cumin and coriander ), flowers (clove and apen),bulbs (garlic), and rhizomes (bengle, dlingo, and black curcuma). Other complementaryingredients are hot fresh water, salt, snakehead murrel, and starch. Third, herb/prescriptionprocessing methods include: (a) burning, (b) steaming in a rice steamer, (c) chewing, (d)smoothing, and (e) boiling. Fourth, the medical care methods include cekok (force-feeding)and sembur (spraying from the mouth for an external treatment).Keywords: traditional medical care, Javanese manuscript, cekok, sembur
A C onstraint on Planck-scale M odications to Electrodynam ics w ith C M B polarization data

Field: Physics and Astronomy (Physical Sciences)

A bstract. W e show that the Cosm ic M icrowave Background (CM B) polarization data gathered by the BOOM ERanG 2003ightand W M AP providean opportunity to investigate in-vacuo birefringence,ofa type expected in som e quantum pictures ofspace-tim e,with a sensitivity thatextendseven beyond the desired Planck-scale energy. In orderto renderthis constraint m ore transparentwe rely on a wellstudied phenom enologicalm odelofquantum
Molecular glue degraders: exciting opportunities for novel drug discovery

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Expanding the scope of what can be effectively targeted in the development of treatments for diseases that are incurable or resistant to conventional therapies offers new therapeutic options. The treatment of microbial infections and neurodegenerative diseases is a major societal challenge, and the discovery of MGDs appears to be a promising avenue. Combining different approaches to discover and exploit a variety of innovative therapeutic agents will create opportunities to treat diseases that are still incurable.
[Human pharmacokinetics of theophylline and etofylline from different formulations of a cardiotonic (author's transl)].

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Serum concentrations of theophylline and etofylline were analysed by a specific HPLC-method in 6 volunteers after i.v. and p.o. administration of the cardiotonic Cordalin ampoules, drops and dragees. Maximum serum concentrations were reached by theophylline an etofylline at about the same time: 1.0-1.2 h after Cordalin drops; 2.3-2.6 h after Cordalin dragees. The half-life of serum elimination was 5.0-7.2 h for theophylline and 5.5-6.9 h for etofylline. The absolute bioavailability of the two oral formulations was calculated from the areas under the serum curves. For theophylline it is complete from the dragees and 78% from drops. Etofylline, too, is highly bioavailable: 94% from the dragees, 84% from drops. From the kinetic data the conclusion can be drawn that accumulation of theophylline and etofylline will be negligible after Cordalin if administered according to prescribed directions.
Empirical Determinants of Saving in the Islamic Banks: Evidence from Indonesia المحددات التجريبية للادخار في البنوك الإسلامية: أدلة من إندونيسيا

Field: Economics, Econometrics and Finance (Social Sciences)

This study attempts to determine the factors affecting saving in the Islamic banks in Indonesia. By employing the Vector Autoregressive and its associated Impulse Response Function analysis for all Islamic banks in Indonesia from March 2000 to August 2007, the study analyzes the importance of real rate of return on Islamic deposit, interest rate on conventional deposit, real income and number of Islamic bank branches in determining the level of savings in the Islamic banks. The results highlight the influential role of conventional interest rate in determining the level of saving in the Islamic banks. In particular, higher Islamic deposit is significantly correlated with higher rate of return and lower interest rate. Furthermore, the study finds the existence of displaced commercial risk between the Islamic and conventional banks, such that the Islamic banks’ depositors transfer their funds to the conventional banks when the rate of return provided by the Islamic banks is significantly lower than the interest rate of its counterpart. The findings of this study have important implications on the risk management practices in the Islamic banks in Indonesia. تحاول هذه الدراسة تحديد العوامل التي تؤثر على الادخار في البنوك الإسلامية في إندونيسيا، عن طريق استخدام القوة الموجهة الارتدادية تلقائيا وما يرتبط بها من وظيفة تحليل استجابة قوة الدفع لجميع البنوك الإسلامية في الفترة من مارس 2000 إلى أغسطس 2007م، وتحلل الدراسة أهمية معدل العائد الحقيقي على الودائع الإسلامية، وسعر الفائدة على الودائع التقليدية، والدخل الحقيقي، وعدد من فروع البنوك الإسلامية في تحديد مستوى المدخرات في البنوك الإسلامية. والنتائج التي توصل إليها البحث تسلط الضوء على دور سعر الفائدة في تحديد مستوى الادخار في المصارف الإسلامية، وعلى وجه الخصوص فإن ارتفاع الودائع الإسلامية يرتبط بشكل كبير بارتفاع معدل العائد وانخفاض سعر الفائدة. وعلاوة على ذلك، وجدت الدراسة أن مخاطر الانتقال التجارية بين المصارف الإسلامية والتقليدية، ومنها تحويل المودعين في البنوك الإسلامية الأموال إلى المصارف التقليدية عندما يكون معدل العائد التي تقدمها المصارف الإسلامية أقل بكثير من سعر فائدة نظيرتها. نتائج هذه الدراسة مهمة على ممارسات إدارة المخاطر في المصارف الإسلامية في إندونيسيا.
Novel frameshift variant (c.409dupG) in SLC25A38 is a common cause of congenital sideroblastic anaemia in the Indian subcontinent

Field: Medicine (Health Sciences)

Aims Congenital sideroblastic anaemias (CSAs) are a group of rare disorders with the presence of ring sideroblasts in the bone marrow. Pathogenic variants are inherited in an autosomal recessive/X-linked fashion. The study was aimed at characterising the spectrum of mutations in SLC25A38 and ALAS2 genes in sideroblastic anaemia patients, exploring the genotype-phenotype correlation and identifying the haplotype associated with any recurrent mutation. Patients and methods Twenty probable CSA patients were retrospectively analysed for genetic variants in ALAS2 and SLC25A38 genes by direct bidirectional sequencing. Real-time PCR was used to quantify gene expression in a case with promoter region variant in ALAS2 . Three single nucleotide polymorphisms were used to establish the haplotype associated with a recurrent variant in the SLC25A38 gene. Results Six patients had causative variants in ALAS2 (30%) and 11 had variants in SLC25A38 (55%). The ALAS2 mutated cases presented at a significantly later age than the SLC25A38 cases. A frameshift variant in SLC25A38 (c.409dupG) was identified in six unrelated patients and was a common variant in our population exhibiting ‘founder effect’. Conclusion This is the largest series of sideroblastic anaemia cases with molecular characterisation from the Indian subcontinent.
MOESM1 of Using cluster analysis to reconstruct dengue exposure patterns from cross-sectional serological studies in Singapore

Field: Medicine (Health Sciences)

Additional file 1: Table S1. Dengue virus strains used in the PRNT assay and variable codes used in the analysis. Table S2. Top 5 algorithms using weighted rank aggregation and the Dunn index, silhouette width, and adjusted connectivity as validating metrics from the aggregated analysis of the samples collected in 2009 and 2013. Table S3. Top 5 algorithms using weighted rank aggregation and the Dunn index, silhouette width, and adjusted connectivity as validating metrics from the analysis of the samples collectied in 2009. Table S4. Top 5 algorithms using weighted rank aggregation and the Dunn index, silhouette width and adjusted connectivity as validating metrics from the analysis of the samples collected in 2013.
Coordinated transport of phosphorylated amyloid-β precursor protein and c-Jun NH2-terminal kinase–interacting protein-1

Field: Neuroscience (Life Sciences)

The transmembrane protein amyloid-β precursor protein (APP) and the vesicle-associated protein c-Jun NH2-terminal kinase–interacting protein-1 (JIP-1) are transported into axons by kinesin-1. Both proteins may bind to kinesin-1 directly and can be transported separately. Because JIP-1 and APP can interact, kinesin-1 may recruit them as a complex, enabling their cotransport. In this study, we tested whether APP and JIP-1 are transported together or separately on different vesicles. We found that, within the cellular context, JIP-1 preferentially interacts with Thr668-phosphorylated APP (pAPP), compared with nonphosphorylated APP. In neurons, JIP-1 colocalizes with vesicles containing pAPP and is excluded from those containing nonphosphorylated APP. The accumulation of JIP-1 and pAPP in neurites requires kinesin-1, and the expression of a phosphomimetic APP mutant increases JIP-1 transport. Down-regulation of JIP-1 by small interfering RNA specifically impairs transport of pAPP, with no effect on the trafficking of nonphosphorylated APP. These results indicate that the phosphorylation of APP regulates the formation of a pAPP–JIP-1 complex that accumulates in neurites independent of nonphosphorylated APP.
Silver-Catalyzed Aqueous Electrochemical Valorization of Soda Lignin into Aliphatics and Phenolics

Field: Chemistry (Physical Sciences)

Transitioning from crude oil to renewable sources of carbon-based chemicals is critical for advancing sustainable development. Lignin, a wood-derived biomacromolecule, holds great potential as a renewable feedstock, but efficient depolymerization and dearomatization methods are required to fully unlock its potential. In this investigation, we present a silver-catalyzed aqueous electrocatalytic method for the selective depolymerization and partial dearomatization of soda lignin under mild, ambient conditions. Utilizing a water/sodium carbonate solvent system and a silver electrode to mediate the electrochemical reduction, we achieved significant lignin depolymerization over reaction times ranging from 5 to 20 h. Analysis by nuclear magnetic resonance (NMR) and high-resolution mass spectrometry (HRMS) revealed sodium levulinate, sodium acetate, and sodium formate as the main aliphatic products, alongside various aromatic species in the depolymerized lignin products (DL). This selective conversion of lignin into both valuable aromatic compounds and reactive aliphatic intermediates offers promising opportunities for further synthesis of a wide range of organic chemicals, contributing to the development of a more sustainable and circular economy.
Plasmonic materials and manufacturing methods for rapid and sustainable thermal cycler for PCR

Field: Materials Science (Physical Sciences)

Multiple outbreaks of fatal infectious diseases throughout history have intensified the need for early diagnostic methods to efficiently control their spread. Polymerase chain reaction (PCR)-based diagnosis is a sensitive, accurate, and effective method for detecting infections. However, conventional PCR-based diagnosis is slow and consumes large amounts of energy, primarily because of bulky, power-consuming thermal cyclers. Herein, we review recently published PCR-based diagnostic methods, in which plasmonic light-to-heat conversion-based thermal cyclers replace conventional ones. First, we explain the structures of recently developed rapid plasmonic-based thermal cyclers and review the various materials used. Next, we review the fabrication methods used in recent developments in rapid plasmonic thermal cyclers. Then, we discuss sustainable methods that have been and can be implemented to develop a rapid plasmonic thermal cycler. With this review, the requirements for developing a plasmonic-based sustainable PCR with high speed, accuracy, and sensitivity can be understood to contain future pandemics.
Accommodation and Scotopic Visual Acuity

Field: Neuroscience (Life Sciences)

Changes in scotopic acuity as a function of varying states of natural accommodation have been measured with targets at various distances and luminances. Results for two observers showed that the amounts of negative accommodation needed to produce maximum acuity increased with decreasing luminance or increasing target distance at a constant luminance. The amount of natural negative accommodation needed for maximum acuity was much less than has been found with the use of spectacles and natural accommodation for infinity. There appeared to be a critical luminance level at which changes in accommodation produced minimal changes in acuity. The effect of red vs white fixation lights was also investigated.