jimnoneill/paper-to-field-training huggingface dataset:
The effect of luteal phase prolongation with medroxyprogesterone acetate on endometrial thickness and pregnancy rate in women following recurrent implantation failure

Field: Medicine (Health Sciences)

Introduction: Assisted reproductive technology (ART) is increasingly used to help infertile couples to have a child. However, less than one-third of transferred embryos result in successful implantation and live birth. Recurrent implantation failure (RIF) is an outstanding barrier to pregnancy achievement by this advanced technology. This study was conducted to evaluate the hypothesis that luteal phase prolongation would lead to endometrial thickening and decrease the RIF’s rate. Methods: This interventional study was conducted in the infertility clinic of the Alzahra Teaching Hospital and Asadabadi polyclinic, Tabriz, Iran. Sixty women, aged 20–40 years, with a history of RIF following several in vitro fertilization treatment cycles with mid-luteal progesterone levels less than 3 ng/mL, and endometrial thickness less than 8mm were recruited through the purposive sampling method. Participants were treated for six cycles with oral medroxyprogesterone acetate (MPA) tablet 5 mg/12 h initiated from the 16th day of their menstrual cycle for 20 days and evaluated for study outcomes during this course. Endometrial thickness was compared before and after MPA administration in the whole study population. The pregnancy rate was determined. Pregnancy complications and conditions were evaluated during the study. Results: Endometrial thickness was increased in patients after MPA administration (mean difference [95% CI]: 2.66 [2.43 to 2.89]; P<0.001). Overall, 80% (n=48) of participants achieved biochemical pregnancy during a 6-month treatment. Four pregnancies out of 48, were lost in different stages of pregnancy. One participant experienced gestational diabetes in the 24th week of pregnancy. No embryo-fetal abnormality was present until delivery. Conclusion: Administration of MPA following RIF induces endometrial development and facilitates embryo implantation by luteal phase prolongation which results in natural pregnancy achievement followed by timed intercourse.
Empowering leadership and socio-technological practices: an empirical investigation of BTS’s success

Field: Business, Management and Accounting (Social Sciences)

Purpose This study explores the global phenomenon of BangTan Sonyeondan (BTS), a Korean singing group, from an under-researched art and entertainment market perspective. We introduce a research model to delineate the impacts of leadership motivation, socio-technological practices and global prominence outcomes. Design/methodology/approach The theoretical foundation clarifies the research context, justifying the relevance of key concepts, linking them to primary research questions and forming the basis for a well-structured empirical investigation. Our research model presents the flows of leadership influence, training practices, technology use and global prominence outcomes. Utilizing a survey instrument, we gathered data from BTS fans and analyzed the empirical findings. Findings BTS’s success is attributed to unique factors: (1) upstream flow of leadership influence; (2) process flow of internal service training and technological excellence, fostering stakeholder enthusiasm. The results indicate that service empowerment leadership is crucial in driving talent development and appropriate technology use, enhancing brand reputation. Fan loyalty and collective passion are key moderators in these dynamics. Research limitations/implications While focused on BTS, our findings have broader applicability in entertainment organizations, underscoring the relevance of socio-technological theory in understanding phenomena similar to BTS’s success. Practical implications Long-term brand performance in service organizations extends beyond financial metrics and necessitates empowering service leadership, training for key performers, technological infrastructure and managing personal interactions and group dynamics. Originality/value This study is unique in applying a leadership motivation perspective and socio-technological theory to BTS’s long-term success, utilizing BTS fans’ views to examine and assess their success factors and outcomes.
Analisis Pesan Dakwah Nabi Muhammad SAW Dalam Piagam Madinah

Field: Arts and Humanities (Social Sciences)

Prophet Muhammad SAW is the most important figure when discussing the da'wah activities that exist in and outside the Arab region until it spread throughout the world as it is today. Based on historical facts, his stories and examples in da'wah contain messages of goodness and wisdom, some examples of his da'wah messages can be seen in the Medina Charter which is used as a written da'wah media, legal and recognized by the Medina community at that time. The purpose of this study is to find the da'wah messages contained in the document. This study uses a descriptive qualitative method. The subject of this study is the text of the Medina Charter and the object is the da'wah message. The data collection technique in this study was carried out by collecting information and data obtained from various literature, such as books, scriptures, and journals. The data analysis technique was carried out using the content analysis method. The results of the study show that the 47 articles of the Medina Charter contain Islamic teachings in the holy book and the prophet's sunnah, including messages of unity of the people, brotherhood, equality, freedom, harmony between religious communities, doing good to neighbors, helping each other, peace, recommendations for deliberation, justice, implementation of the law, leadership, and piety which are proven or accompanied by explanations of each message in the Qur'an and hadith. Thus, it can be concluded that the tendency of the messages contained in the Medina Charter is a message of preaching to realize a social life that is in accordance with the rules of Islamic teachings in the Qur'an and hadith
To Help “La Gente”: Examining Helping People as a Motivation for Becoming an Officer in the Los Angeles Police Department Among Male Mexican American Officers

Field: Social Sciences (Social Sciences)

The most commonly declared motivation for pursuing a career in law enforcement is helping people. As part of a study focusing on male Mexican American police officers in the Los Angeles Police Department, data were collected on initial motivations of police officers. The data reveal that a significant motivation for respondents was not only helping people but specifically helping minority communities receive improved services. This motivation stems from their interactions and perception of police while growing up in minority communities. Based on the findings, this article concludes with a call for a more grounded approach to research on Latinos in law enforcement.
A new network application framework based on Component development and multi-threaded technologies

Field: Computer Science (Physical Sciences)

According to the classical business logicalness of the network applications, based on techniques of component development and object-oriented design, a new software framework with good reusability was established. The design resolutions dealing with the data receiving, sending, processing, recording and human computer interaction (HCI) managing, were proposed, which supports multi-sources, multi-targets, multi-categories, large amount of data, high-speed network receiving and sending, data processing based on the priority control and multi-threaded, and faultless data recording based on database. Class libraries, including data-storing management, thread synchronization management, cross threads data-accessing management, network receiving and sending management based on multi-sockets, were also implemented. Experimental results show that the new presented infrastructure has good performance, and shows better support ability for similar applications development.
ChemInform Abstract: α,β‐Unsaturated Thiolates and Their Analogues in Cycloaddition Reactions. Part 18. Reaction of 2‐ Phenylethynyltellurolates with C‐Ethoxycarbonyl‐N‐phenylnitrilimine.

Field: Chemistry (Physical Sciences)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
V.A. Drits & C. Tchoubar X-ray Diffraction by Disordered Lamellar Structures. Theory and Applications to Microdivided Silicates and Carbons. Springer-Verlag, Berlin, 1990. xvii + 371 pp. Price DM 268. ISBN: 3.540.51222.5

Field: Materials Science (Physical Sciences)

V.A. Drits & C. Tchoubar X-ray Diffraction by Disordered Lamellar Structures. Theory and Applications to Microdivided Silicates and Carbons. Springer-Verlag, Berlin, 1990. xvii + 371 pp. Price DM 268. ISBN: 3.540.51222.5 - Volume 27 Issue 2
The effect of RNAi-mediated gene silencing on her-2/neu gene expression in lung adenocarcinoma cells

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Objective: Her-2/neu protein overexpression has been demonstrated in Non-small cell lung cancer, especially in lung adenocarcinoma. Its overexpression often indicates a poor prognosis. Therapeutic agents against her-2/neu have been intensively sought over the past decades. The objective of this paper is to investigate the effect of chemically synthesized siRNA targeting her-2/neu on her-2/neu dysregulated human lung adenocarcinoma cells. Methods: Calu-3 cells were transfected with siRNAs formulated LipofectAMINE 2000. The her-2/neu mRNA and protein levels were detected by RT-PCR and flow cytometry (FCM). The biological morphology and growth inhibition of calu-3 cells were observed with light microscopy and MTT assay, respectively. The cell cycle and apoptosis rate were analyzed by FCM. Results: siRNA targeting Her-2/neu down-regulated the transcription of her-2/neu oncogene and protein level. Slowed cell proliferation and cell cycle arrest at G0/1 stage could be also observed, accompanied with enhanced cell apoptosis. Conclusion: Specific siRNA targeting her-2/neu can effectively inhibit her-2/neu expression in her-2/neu overexpressing calu-3 cell lines. siRNA-mediated gene silencing may be a useful therapeutic strategy for cancer.
Multi‐channel shopping: channel use among rural consumers

Field: Business, Management and Accounting (Social Sciences)

Purpose The research purpose was to identify whether changes occurred between 2000 and 2003 in the retail channel use of rural consumers for searching product information and for purchasing food and fiber products and to investigate whether differences existed between channel use groups (i.e. store only shoppers, store and catalog shoppers, and multi‐channel shoppers) concerning perceived time property, satisfaction with local offerings, community attachment, shopping criteria, and financial security. Design/methodology/approach Survey methodology was used. Questionnaires were mailed to participants living in non‐metropolitan statistical areas of the USA with populations less than 12,500. In 2000, 2,198 participants returned the questionnaire. Follow‐up questionnaires were mailed to the same participants during 2003 and returned by 847 participants. The analysis is based on the responses of the 847 participants. Findings To search for information on apparel, food, or home furnishing products, internet use increased slightly as did use of the internet to purchase apparel and home furnishings. Multi‐channel shoppers rated themselves as time‐pressed, dissatisfied with local offerings, unattached to their community, and unconcerned with financial security while shopping. Practical implications Rural consumers are slowly increasing their use of internet even as they report their satisfaction with shopping with local brick and mortar stores increased during the time period studied. The time is right for rural retailers to enhance both personal and professional relationships with their customers. Rural retailers can capitalize on consumer satisfaction and provide outstanding value and service to keep local customers in local markets. Originality/value The paper provides information on new and different retailing practices that satisfy rural consumers in the USA.
Basic Study of cell apoptosis for cinobufacini on human laryngeal carcinomacell

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Objective To investigate the effects of cinobufacini on oncogenes in human la-ryngeal carcinoma cell line Hep- 2. Method In our experiment, the effect of cinobufacini on theproliferation of Hep-2 was observed by using the following methods: the morphologic changesof the cells were observed with optical and transmission electron microscopy, the cytotoxicity ofcinobufacini to these cell lines were measured by MTT assay, the expresser gene was determinedwith SP immunohistochem1stry, flow cytometry and image analysis. Result The results showedthat when Hep-2 cells were treated with cinobufacini for 24 hours, the cell proliferation was in-duced and cell became well -differentiated. When Hep -2 cells treated for 120 hours, the celldeath occurs by apoptosis. The expression of the oncogenes C-myc and Bcl-2 protein were re-markably decreased whereas that of the tumor suppresser gene P53 protein seems to increas.DNA content in the cycle progression of Hep - 2 cell was assessed by flow cytometry. lt wasfound that after Hep - 2 treated with cinobufacini 24 hours DNA synthesis was suppressed withsignificant GI block. Conclusion The antitumor effect and induce for the differentiation ofclnobufacini might be by Ineans of inhibiting the expression of oncogenes and improv1ng the ex-pression of carcinoma suppresser gene.[
Effect of heavy metals on soil respiration during decomposition of sugarcane (Saccharum officinarum L.) trash in different soils

Field: Environmental Science (Physical Sciences)

An experiment was conducted to study the effect of heavy metals (Cd, Cr and Pb), soil texture (sandy, loam and clay) and incubation periods (7, 15, 30, 60, 90 and 120 days) on soil respiration (CO2 evolution) during sugarcane trash decomposition in laboratory conditions of the Indian Institute of Sugarcane Research, Lucknow, India. Surface soils (0-15 cm) were collected from agricultural fields and crop residue of sugarcane trash (Saccharum officinarum L.) was taken in the institute farm. Crop residue (10 t/ha) and heavy metals (10, 50, 100, 1000 μg/g) were mixed and incubated at 30°C ± 2°C in an incubator. The rate of soil respiration (CO2 evolution) decreased with increasing heavy metals concentration. During the 120 days, the toxicity decreased but still remained significant. Maximum soil respiration was recorded at 7 days of incubation period; further, it decreased with increasing incubation period. The highest drop of soil respiration rate was caused by addition of 1000 μg/g Cd, Cr and Pb levels. Clay soils evolved maximum CO2 followed by loam and sandy soil.
Multiple X-Ray Beam Radiography for Detecting Dental Demineralization

Field: Dentistry (Health Sciences)

The purpose of this study was to develop the radiographic technique for detecting the demineralization which is known as indication of dental caries. This technique was based on the comparing of multiple radiographs which was irradiated by multiple X-ray spectra. For the meaningful comparison, the multiple radiographs were reconstructed to the dosimetrically consistent images using a standard material. The difference of resulting images of same target with multiple spectra represents the difference of response of material as regards the spectra. Consequently, we have found about 10% of demineralization of dental hard tissues particularly in the proximal region through the analyzing of differences. Most intriguing thing in this investigation was that the method to analyze difference shows us to an anatomic structure of dental hard tissues even if absolute values of optical density were excluded during the procedures.
Agricultural Land Carrying Capacity and Shift of Land Use in Upstream of Grompol Watershed, Central Java Province

Field: Environmental Science (Physical Sciences)

This research was conducted in the upstream of Grompol watershed. This study aims to identify: 1) the changes of agricultural land carrying capacity, and 2) the shift of agricultural land use. Primary data of the research were obtained from field observation to know land use in Grompol watershed, while the secondary data were obtained from various stakeholders that were in accordance with the required data. The result of data analysis and data interpretation, it can be known that: 1) the agricultural land carrying capacity in Grompol watershed is in deficit state. In 2003, Karang is the only village that is surplus, while in 2007 and 2014 both Karang and Tohkuning experienced a deficit; 2) the shift of agricultural land use in the upstream of Grompol watershed sampled by Karang and Tohkuning village in 2000, 2007, and 2015 shows that the paddy fields and unirrigated field turned into settlements. During the last sixteen years, the agricultural land in the upstream of Grompol watershed has decreased about 15.68 ha.
Food supply and the obesity scourge: Is there a relationship?

Field: Social Sciences (Social Sciences)

Open access articles are distributed under the terms of the Creative Commons Attribution License, CC BY (or the Creative Commons Attribution-NonCommercial License CC BY-NC), which allows users to (noncommercially) copy, use, distribute, transmit and display the work publicly and to make and distribute derivative works, in any digital medium for any responsible purpose, subject to proper attribution of authorship.
Physicochemical Characteristics and Biological Activities of Rice and Amaranth Fermented by Bacillus subtilis KMKW4

Field: Agricultural and Biological Sciences (Life Sciences)

본 연구에서는 김치에서 분리한 Bacillus subtilis KMKW4를 이용하여 백미 및 아마란스를 영양원으로 발효하였으며 발효물의 배양 특성과 항산화 활성 및 생리활성을 조사하였다. 백미와 아마란스의 비율별로 제조한 발효물 중 아마란스 20%가 첨가된 R80의 생균수가 가장 높았고 pH 또한 낮아 발효가 잘 진행되었음을 확인하였다. 발효물의 amylase 활성을 측정한 결과 R100, R90, R80, R70 중 R80에서 48시간 배양 시 57.77 unit/mL로 가장 높아 R80을 곡류 효소함유 제품 개발을 위한 혼합조건으로 선정하였다. 발효물의 동결건조분말에 대한 amylase 활성도 발효물과 동일하게 48시간에서 가장 높게 나타나 동결건조 후에도 효소 활성이 유지되는 것을 확인하였다. 발효물 동결건조분말의 유리당 함량은 발효 후 R80에서 maltose는 검출되지 않았으며, glucose는 5,454.2 mg/100 g으로 함량이 증가하였고 R100보다 높음을 확인하였다. 유리아미노산 함량은 R100의 경우 발효 전 664.9 mg/100 g에서 48시간 발효 후 834.2 mg/100 g으로 증가하였으며, R80은 발효 전 868.8 mg/100g에서 발효 후 1,085.2 mg/100 g으로 증가하였다. 항산화 활성은 발효함에 따라 증가하였으며 R100보다 R80에서 우수하였다. ACE 저해 활성은 발효 전 R100과 R80에서 각각 30.12%와 40.22%로 나타났으며 발효 후에는 각각 59.13%와 78.57%로 나타나 발효가 진행됨에 따라 증가하는 경향을 보였고 R80이 R100보다 더 높은 ACE 저해 활성을 나타내었다. α-Glucosidase 저해 활성은 모든 실험군에서 발효 전보다 발효 후에 높은 저해 활성을 나타내었으며, R100보다 R80이 우수하여 향후 곡류 효소 함유 식품 제조를 위한 소재로 활용 가능하다고 사료된다.
Deep Casa for Talker-independent Monaural Speech Separation

Field: Computer Science (Physical Sciences)

Monaural speech separation is the task of separating target speech from interference in single-channel recordings. Although substantial progress has been made recently in deep learning based speech separation, previous studies usually focus on a single type of interference, either background noise or competing speakers. In this study, we address both speech and nonspeech interference, i.e., monaural speaker separation in noise, in a talker-independent fashion. We extend a recently proposed deep CASA system to deal with noisy speaker mixtures. To facilitate speech enhancement, a denoising module is added to deep CASA as a front-end processor. The proposed systems achieve state-of-the-art results on a benchmark noisy two-speaker separation dataset. The denoising module leads to substantial performance gain across various noise types, and even better generalization in noise-free conditions.
β-ADRENERGIC STIMULATION OF PROLACTIN RELEASE FROM SUPERFUSED PITUITARY CELL AGGREGATES1

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

l-Isoproterenol (l-ISO), a specific agonist of beta-adrenergic receptors, evoked a prompt rise of prolactin (PRL) release from superfused anterior pituitary cell aggregates established in culture for 5 days. The effect was concentration-dependent between 1 and 100 nM. d-Isoproterenol was more than 2 orders of magnitude weaker than the l-isomer. When dopamine receptors were blocked with domperidone, PRL secretion was also stimulated by l-epinephrine (E) and l-norepinephrine (NE), the rank order of potency being l-ISO greater than E much greater than NE. Under the latter conditions dopamine and the alpha-adrenergic agonists, clonidine and phenylephrine, had no stimulatory effect at 1 microM. Stimulation of PRL release by l-ISO and E was blocked by the beta-receptor antagonist, propranolol, but not by the alpha-receptor blocker, prazosin.
Reconstructing pedigree information in the Reggiana cattle breed based on high density SNP data

Field: Agricultural and Biological Sciences (Life Sciences)

Reggiana is an autochthonous cattle breed, mainly reared in the North of Italy. Milk of Reggiana cows is almost exclusively used for the production of a mono-breed branded Protected Designation of Origin (PDO) Parmigiano-Reggiano cheese. Reggiana population size experienced a dramatic reduction in the past, which was then reverted after 1980’. As in many local breeds, Reggiana pedigree records are not always complete and partial recording may increase error rate in several applications, such as inbreeding coefficient calculation and definition of selection plans. Highthroughput genotyping data could help to identify and then correct pedigree errors. A few approaches have been proposed to identify pedigree inconsistencies using DNA markers. Opposing homozygotes (OH) define parentage inconsistencies in candidate parent-offspring pairs based on homozygous single nucleotide polymorphisms (SNPs) for alternative alleles. In this work, available Reggiana pedigree information has been used as a starting point for reconstructing problematic records using OH evaluation. A total of 2730 Reggiana cattle, including commonly used 50 sires, have been genotyped with the GGP Bovine 150K SNP Chip. PLINK software and ad hoc scripts have been used to filter and to obtain all pairwise comparisons of the genotyped cattle based on OH. The genotyping error rate was estimated and then used to define the threshold of the number of inconsistent OH SNPs to declare an incorrect pedigree. Parentage information from pedigree records was not correct for about 10% of the animals. The routine application of this method will improve both the managing and conservation of Reggiana cattle breed and will improve accuracy of estimated breeding values.