jimnoneill/paper-to-field-training huggingface dataset:
Effects of aerobic and resistance exercise in murine models of rheumatoid arthritis and osteoarthritis – a systematic review

Field: Medicine (Health Sciences)

Introduction and objective Rheumatoid arthritis (RA) is an inflammatory and systemic autoimmune disease that affects peripheral joints leading to joint degradation, pain, deformities, decreased activities of daily living, and sedentary lifestyle, resulting in secondary sarcopenia. Osteoarthritis (OA), in turn, is a multifactorial disease associated with joint degeneration and impairment of the musculoskeletal system as a whole, affecting joint movement and stability. In both pathologies, there is loss of muscle mass and functional impairment, and physical exercise is a therapeutic alternative to minimize these consequences. The aim of the review is to demonstrate the effects of different physical exercise modalities on muscle mass loss in murine models of OA and RA Materials and method The databases used were PUBMED, EMBASE, Cochrane Database, LILACS, and Google Scholar. The review included studies which induced experimental models of OA or RA in rats or mice; used any exercise modality as an intervention; and analyzed some quantitative muscle histomorphometric measurs. The search strategy included all keywords on the topic identified in previous research and adapted for each database. Studies published in any language and in any year were included. An analysis of the studies was performed by two independent reviewers and data were extracted from the articles using tools developed by the reviewers. Results After completing the definitive search in the databases, 193 studies were found, of which only 2 were included in this review, one addressing the effects of resistance exercise in rats with RA, and another using aerobic exercise to treat rats with OA. Conclusion Treatment with different forms of physical exercise contributed to attenuation of muscle mass loss in animal models of OA and RA.
Current and Future Challenges Facing Chinese Defence Industries*

Field: Social Sciences (Social Sciences)

Abstract The fundamental questions are simple. Can the Chinese defence indus tries make what the People’s Liberation Army (PLA) needs? Can they develop and produce systems to allow the PLA first to overcome its problem of “short arms and slow legs,” secondly to move from brown water coastal defence to green-water offshore defence (and eventually blue-water power projection), and thirdly successfully to conduct “limited wars under high-tech conditions”? Indeed, in a larger sense, can the defence industry, under the conditions and pressures of economic reform, survive except by “converting”? The answers, however, are not as simple as might be thought.
Genomic changes driving the acquisition of multidrug resistance in Candida glabrata

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

This project was set out to broaden our knowledge of the processes driving the emergence of antifungal drug resistance in an opportunistic yeast pathogen Candida glabrata. More precisely, we sought to find the mutational signatures of drug resistance and cross-resistance to representatives of two clinically important antifungal drug classes, azoles and echinocandins. By combining in vitro evolution with phenotypic screening and comparative genomics analysis we investigated the relationship between genomic changes, fitness and drug susceptibility to shed light on the cellular mechanisms and evolutionary constraints of antifungal drug resistance in this important pathogen
Lymphocytes in Breast Tissue

Field: Medicine (Health Sciences)

Journal Article Lymphocytes in Breast Tissue Get access Chandnish K. Ahluwalia, M.D., Chandnish K. Ahluwalia, M.D. Search for other works by this author on: Oxford Academic Google Scholar William H. Kern, M.D. William H. Kern, M.D. Search for other works by this author on: Oxford Academic Google Scholar American Journal of Clinical Pathology, Volume 94, Issue 6, 1 December 1990, Pages 801–802, https://doi.org/10.1093/ajcp/94.6.801a Published: 01 December 1990
Oligocene - Miocene Ice Sheet and Paleoceanographic Evolution of the Eastern Wilkes Land Margin

Field: Earth and Planetary Sciences (Physical Sciences)

This thesis shows that before 28 Ma a single water mass flowing westward, the proto-AABW, occupied the seafloor in the studied region. The first evidence for the onset of a current flowing eastward, the proto-CDW, is found at 28 Ma. Between 26 and 25 Ma ice sheets were mainly continental-based and an oceanic frontal system already existed and migrated during glacial-interglacial cycles that were paced by obliquity. The late Oligocene frontal system was however weaker than today´s Polar Front because we find evidence for intrusion of warm north component waters close to the Antarctic margin. The latest Oligocene (24-23.4 Ma) witnessed at least eight times of ice sheet advancing into the continental shelf and retreats inland, pointing to a highly dynamic ice sheet during the cooling trend leading to the glacial Mi-1 event. During this period, we interpret that the EAIS in the WSB becomes marine-based as a consequence of the erosion and overdeepening of the Wilkes Subglacial Basin by the repeated advances and retreats of the EAIS since it was formed in the early Oligocene (33.6 Ma).
Solar patrol observatory at the Silesian University of Technology

Field: Physics and Astronomy (Physical Sciences)

The Silesian University of Technology Observatories (SUTO) group’s solar patrol station, SUTO Solar, is designed to collect patrol images of the Sun. The observatory is operated remotely and equipped with a 60-mm Lunt telescope for imaging in the Hα 656.28 nm hydrogen line and an 80-mm Sky Watcher refractor for imaging in the continuum centered at 540 nm. Both telescopes use complementary metal-oxide-semiconductor (CMOS) cameras. A set of environmental sensors measuring temperature, humidity, and pressure provide information about the optical instruments. Real-time full-disk images and archival data are shared via a dedicated web page. In future work, low-resolution images generated by SUTO Solar will be used as training datasets for dedicated machine learning algorithms designed to enhance images acquired by small instruments.
Coordination Complexes with <i>cis-</i>TCNE Radical Anion Ligands. Models\nof M[TCNE]<sub>2</sub> Magnets

Field: Chemistry (Physical Sciences)

The synthesis and characterization of two manganese(II) complexes\nformally each featuring two <i>cis-</i>tetracyanoethylenide radical anionic\nligands (TCNE<sup>•/-</sup>) are reported. In each case, tris(pyrazol-1-ylmethyl)amine serves as a capping ligand, blocking three facial\ncoordination sites. Crystal structures show that the two TCNE\nanions in each molecule exhibit an intramolecular stacking\ninteraction that forms what can be considered a coordinated\n(TCNE<sub>2</sub>)<sup>2-</sup> moiety. These molecules are presumed to be structural\nmodels of some of the local bonding in the family of amorphous,\nferrimagnetic, M[TCNE]<sub>2</sub>·<i>y</i>(solvent) coordination polymer magnets.\nMagnetic measurements indicate that the (TCNE<sub>2</sub>)<sup>2-</sup> bridge is\ndiamagnetic and not a good mediator of magnetic exchange, a\nresult that might explain the observed lower ordering temperatures\nin some of the polymer magnets.
Commodity Market Instability and Development: Issues and Policies

Field: Economics, Econometrics and Finance (Social Sciences)

The paper review various aspects of commodity market instability and development, with the purpose to identify whether research has dealt with some of the pressing issues relating to the topic during the past years, and to identify promising areas for further research. Particular emphasis is given to the areas of distortions, asymmetries, and irreversibilities, and it is revealed that while these topics are very relevant, not enough research has addressed them. The paper concludes by discussing the various policies that can be implemented at the international levewl to alleviate problems of food commodity market instability.
Tomaso da Modena: painting in Emilia and the march of Treviso, 1340-80

Field: Arts and Humanities (Social Sciences)

List of colour plates, text figures, comparative illustrations Photographic sources Preface Part I: 1. Introduction 2. Modenese origins 3. Bologna 4. Treviso: the Capitolo of the Dominicans 5. Votive frescoes and decorative schemes in the churches of Treviso 6. S. Margherita 7. Works of Tomaso's maturity in Modena and elsewhere 8. Karlstejn 9. Tomaso's last work and its influence in Emilia 10. Tomaso's influence in the Veneto Part II: 11. Documents concerning Tomaso 12. Catalogue Bibliography Index Plates.
MULTI-SCALE DYNAMICS OF SPONTANOUS BRAIN ACTIVITY CORRELATE WITH WALKING SPEED IN COMMUNITY-DWELLING OLDER ADULTS

Field: Neuroscience (Life Sciences)

The control of walking depends upon the exchange of information across numerous brain networks. Within a given brain region, spontaneous (i.e., resting-state) fluctuations in neuronal activity are “complex,” containing meaningful information over multiple temporal scales. While this complexity appears to decline with advancing age, it is unknown if it associates with walking performance. The aim of this study was to determine the relationship between resting-state complexity and walking speed in older adults. Forty-three older adults from the MOBILIZE Boston Study completed a resting-state MRI and on a separate visit, assessment of walking under normal conditions (i.e., single-task) and while performing a cognitive serial-subtraction task (i.e., dual-task). Resting-state complexity within 50 pre-defined brain regions was calculated by computing the ‘multiscale entropy’ of the blood-oxygen-level-dependent time-series of each voxel, and then averaging across all voxels of each region. A machine learning technique termed ‘leave-one-subject-out support vector regression,’ adjusted for age, indicated that the estimation of both single- and dual-task walking speed based upon regional resting-state complexity was high (r>0.38, p<0.007). The complexity of seven clusters with known involvement in motor control, attention and/or executive function correlated with both single- and dual-task walking speed (mean p<0.05, mean r>0.31). Four additional regions associated with attentional control were correlated with dual-task walking speed only (mean p<0.03, mean r>0.35). This study revealed that in older adults, walking speed correlates with region-specific multi-scale dynamics of resting-state brain activity, and dual task walking may be particularly dependent upon brain regions that give rise to the control of attention
THE MECHANISM OF COPOLYMER RETENTION IN INTERACTIVE POLYMER CHROMATOGRAPHY. II. GRADIENT SEPARATION

Field: Chemistry (Physical Sciences)

Abstract The molecular-statistical theory of polymer solutions in confined media is applied to the conventional chromatographic theory of gradient elution. This approach leads to the prediction of the special mode of interactive polymer chromatography: gradient elution at critical point of adsorption. We demonstrate theoretically and experimentally that under appropriate conditions elution of each compositionally homogeneous fraction of copolymer occurs at the critical mobile phase composition. This critical mobile phase composition depends only on the local structure of the copolymer chain and is independent of its molecular weight. As a consequence, gradient elution produces the chemical composition distribution of the copolymer. The theory provides the quantitative conditions for statistical copolymer chains to have a single transition point. Equations describing relationships between the critical eluent composition and the chemical composition and microstructure of macromolecules are developed. The experimental verification of the theory was performed by the normal phase isocratic and gradient elution of chlorinated polyethylene with various chemical compositions (chlorine content) and molecular weights. To the best of our knowledge, these experiments, for the first time, demonstrate the existence of the adsorption-desorption transition point for statistical copolymers. The gradient separation at the critical point of adsorption can be applied also to other complex polymers containing various types of molecular heterogeneity. Acknowledgments
Evaluasi Stimulasi Hydraulic Fracturing Dan Analisa Produktivitas Sumur Pada Formasi Sandstone Sumur ”MG-09” Lapangan ”FI”

Field: Energy (Physical Sciences)

Hydraulic fracturing is a stimulation method by injecting treatment fluid to fracture a formation by using proppant (sand) as a fracture buffer media which aims to improve the production rate in the well. Fracture geometry evaluation is done to get the right fracture geometry value. In the production evaluation, using the Howard and Fast method, the Kavg value in the MG-09 well was 39.4094 mD. Based on the actual production rate after hydraulic fracturing in well MG-09 there was an increase in the total flow rate from 65 BLPD to 182 BLPD. Based on the calculation of the increase in Productivity Index, the Prats method obtained an increase in PI of 2.63 times, while the CSD method (Cinco-ley, Samaniego and Dominique) obtained a multiple of the increase in productivity (K2P) or an increase in PI of 2.63 times and the skin factor of +12 to -4.8 Based on the comparison of the three-phase IPR curve of the Pudjo-Sukarno method, where at the same Pwf of 400 psi there was an increase in oil production from 45 BOPD to 134 BOPD. Therefore, the results of the hydraulic faracturing evaluation of the MG-09 well in terms of the work process (proppant, fracturing fluid), production analysis (permeability, productivity index, increased productivity index of the prats and CSD methods, level of skin repair and IPR curve analysis) were declared successful.
Gender, Eating Disorders, and Graphic Medicine

Field: Arts and Humanities (Social Sciences)

Developing an understanding of eating disorders beyond the biological/medical framework has become a necessity in present times, especially when eating disorders are swiftly spreading deep roots across the world. In view of the multidimensional etiology of eating disorders, there are increased efforts towards understanding its phenomenological, cultural, and other related non-medical aspects, and Gender, Eating Disorders, and Graphic Medicine leaps past the prevalent notions on eating disorder, and contributes to the developing corpus of affective knowledge on eating disorders among women through comics and graphic medicine. Taking cues from select graphic narratives on eating disorders, this book attempts to posit graphic medicine as one of the most befitting modes of life writing. This book is distinctive in that it is an attempt not only to explore the multi-dimensional etiology of eating disorders in women using graphic medicine narratives but also to understand how graphic medicine humanizes eating disorders by offering a unique ingress into women's phenomenological experience of eating disorders.
Explaining venture capital firms' syndication behaviour: A longitudinal study

Field: Business, Management and Accounting (Social Sciences)

Using a unique methodological approach, this paper examines the factors related to venture capital firms' (VCFs') involvement in syndication. It is argued that VCFs' investment strategies matters in terms of the extent to which VCFs engage in syndication. Several hypotheses pertaining to VCFs' syndication behaviour are tested based on a longitudinal data set of the realized strategies of 200 US-based VCFs over a 12-year period. Overall, support is found for both knowledge-based and financial arguments for why VCFs engage in syndication. Results are discussed and avenues are provided for future research.
Abstract 17048: The Association of Neighborhood Deprivation With Racial Disparities in 30-day Heart Failure Readmissions in Middle Aged Adults

Field: Medicine (Health Sciences)

Introduction: Neighborhood socioeconomic status (N-SES) is associated with incident heart failure (HF) and HF readmissions. N-SES may have a greater impact on young and middle-aged adults with heart failure (HF) due to fewer resources. Hypothesis: N-SES modifies the disparity in 30-d HF readmissions between Blacks and Whites in the Southeastern US. Methods: We created a geo-coded retrospective cohort of patients aged <65 years (N=11,469, mean age 52.1 yrs, 48% female, 46.5% Black) with at least one HF hospitalization at any Emory Healthcare facility from 2010-2018. Quartiles of the Social Deprivation Index (SDI), derived from US Census data, characterized neighborhood deprivation at the census tract level. Linear probability models estimated the “excess 30-d HF readmissions” between Blacks and Whites (referent) within each quartile of neighborhood deprivation. A base model accounted for geographical clustering, age, gender, and insurance type; a fully adjusted multivariable model further adjusted for clinical variables (composite Charlson Comorbidity Index, HbA1c, BP, SaO2, and HR). Results: Compared with Whites, Blacks were more likely to reside in deprived census tracts, be female, have public insurance, and higher comorbidity scores (Table 1). Between 2010-2018, 20.5% of Black and 12.5% of White patients experienced a 30-d HF readmission (p<.001). Black excess in HF readmissions ranged from 6.7% (95%CI: 3.6%-9.7%) to 8.4% (95%CI: 4.9%-12.0%) within the 2 nd and 4 th deprivation quartiles, respectively (Figure 1), with no excess readmissions in the least deprived quartile. Accounting for comorbidities and clinical presentation eliminated the Black excess in 30-d HF readmissions in the 2 nd quartile but not within higher levels of area deprivation. Conclusions: Excess 30-d HF readmissions in middle aged Blacks increases with neighborhood deprivation and was not explained by patient sociodemographics or comorbidities in the most deprived Census tracts.
Bioluminescence‐based assays for assessing eco‐ and genotoxicity of airborne emissions

Field: Environmental Science (Physical Sciences)

Abstract Ecotoxicological tests (or bioassays) are controlled, reproducible tests where ecological responses are determined quantitatively. Due to numerous difficulties arising when airborne emissions are sampled, relatively few ecotoxicological assays have been applied. Aerosol particles are generally collected on a filter, which limits the quantity of the sample, thus also limiting the range of available test organisms. Bacterial bioassays require low sample quantity, and make a good choice when eco‐ or genotoxicity of the sample are to be determined. Of bacterial assays, the bioluminescence inhibition test has been proven applicable for assessing toxicity of airborne contaminants. In this paper diverse test protocols and their modifications are reviewed. Copyright © 2016 John Wiley & Sons, Ltd.
Glycosylation in Golgi apparatus of early spermatids of rat. A high resolution lectin cytochemical study.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

In the present study, lectin cytochemistry in combination with enzyme and chemical treatments and ultrastructural immunocytochemistry were applied to investigate the formation of acrosomal glycoproteins in endoplasmic reticulum (ER) and Golgi apparatus (GA) of early rat spermatids. In addition, the vesicles involved in glycoprotein traffic were investigated using a monoclonal antibody against clathrin. The results obtained suggest the occurrence of high mannose and complex type N-linked oligosaccharides and mucin type O-linked oligosaccharides. In N-linked glycoproteins, Man residues are incorporated into the nascent oligosaccharide in the ER, Fuc residues of the inner core of the oligosaccharide in the cis region of GA, GlcNAc in medial cisternae of GA and Gal residues in the transmost cisternae of GA. In O-linked glycoproteins, the addition of GalNAc occurs in cis and trans cisternae of GA. Gal beta 1,3GalNAc sequence was detected in medial and trans cisternae of GA. Sialic acid was detected in both N- and O-linked oligosaccharides in medial and trans cisternae of GA but not in acrosomes. Immunoreactivity to clathrin was observed in the intermediate zone between ER and GA and in vesicles of the trans side of GA.
The Effectiveness of Traditional Indonesian Massage for Reducing Fever in Babies

Field: Health Professions (Health Sciences)

Traditional Indonesian massage is a form of physical therapy and part of cultural identity and ancestral heritage that is maintained and passed on from generation to generation. The phenomenon of traditional Indonesian massage is an important part of the culture and healing tradition, which includes various massage techniques passed down from ancestors and has roots in beliefs, traditional healing practices, and the local heritage of the Indonesian people. Fever in babies can cause anxiety in the mother. A safe solution that minimizes drug side effects is non-pharmacological therapy. This research aimed to determine the impact of traditional massage on reducing fever in babies. This type of research is quantitative research. Sampling was carried out using a purposive sampling technique with a total of 60 babies who had fever criteria. Data analysis used the t-test. The study's results showed that the average temperature measurement for babies before the traditional massage was 38.15 degrees Celsius (low fever), while the average temperature measurement for babies after the traditional massage was 36.78 degrees Celsius (normal). The results of the statistical hypothesis analysis show that traditional massage has a significant effect on reducing fever in babies. This means traditional massage can significantly reduce fever in babies, with an average reduction of 1.37 degrees Celsius. This research contributes to providing information to mothers and midwives about the benefits of baby massage for treating fever, baby growth and development.
Clinical and EEG Studies of Zotepine, a Thiepine Neuroleptic, on Schizophrenic Patients

Field: Medicine (Health Sciences)

The overall effect of zotepine was a "slightly improved" or better response in 20 patients (64.5%), "unchanged" in 10 (32.3%) and "worsened" in 1 (3.2%). Zotepine exhibited some degree of improvement in 54.5% of patients unresponsive to prior drugs. The onset of effect of zotepine was within one month in 19 patients. The improvement rate in the hebephrenic type (66.7%) was almost the same as in the paranoid type. The improvement rate classified by psychopathology was highest for hypobulia, followed by restlessness-excitement and hallucination, depressive mood, hypochondria and delusion. The side-effects were subjective complaints, such as general fatigue, dryness of mouth, sleepiness or fainting in a small number of cases. There was a slight increase in S-GPT in one patient and a slightly increased blood platelet count, also in one patient. Serial EEG changes associated with zotepine studied in another 17 chronic schizophrenics could be classified into three groups: those with increased slow waves, those with enhanced alpha waves and those with unchanged EEGs. There was a positive correlation between the incidence of slow waves and higher plasma levels of zotepine.