jimnoneill/paper-to-field-training huggingface dataset:
Air Traffic Controllers' Fatigue and Stress based on Heart Rate Measurement

Field: Psychology (Social Sciences)

본 연구는 교대근무를 수행하는 항공교통 관제사들의 피로와 스트레스와 이에 영향을 미치는 변수와의 연관성을 규명하는 연구이다. 기존 연구결과에 의하면, 관제사의 피로와 스트레스는 근무경과시간, 관할 항공기의 수, 시정 등과 같은 여러 요소에 영향을 받으며, 또한 관제사의 피로와 스트레스는 심장 박동수에 영향을 미치는 것으로 있다고 알려져 있다. 본 논문에서는 항공교통관제사의 피로와 스트레스에 영향을 주는 요소로 근무경과시간, 관할 항공기의 수, 시정을 설정하고, 각 요소와 피로와 스트레스의 정도를 나타내는 심장박동수에 대한 연구 가설을 설정하였다. 실제 수집된 자료를 활용하여 연구가설을 검정한 결과 항공교통관제사의 심장 박동수는 관할 항공기의 수와 근무시간경과에 영향을 받는 것을 확인하였다. 특히, 동일한 대수의 항공기를 관제하는 경우에도, 근무 시간이 경과에 따라서 관제사의 피로와 스트레스 정도가 증가하는 것을 확인할 수 있었다. This paper is concerned with air traffic controllers' fatigue and stress that they experience during their daily job particularly as being shift workers. Previous researches reveal that the controllers' fatigue and stress increase by several factors including time spent at work, traffic intensity, visibility, etc. The researches also indicate that air traffic controllers' fatigue and stress can be reasonably surrogated by their heart rate. We set three hypotheses relating the influencing factors and the fatigue and stress represented by the heart rates. Using wrist bands, air traffic controllers' heart rates at various situations are collected at Choongju airport. The hypothetical tests explicitly confirm that the heart rate is highly correlated with the traffic level and the time spent at work. In particular, it be shown that even when handling the same traffic level, air traffic controllers' stress level increases as the time they spent at work increases.
Study of Bacteriological pathogen causing neonatal sepsis at NICU in Ad-din medical college hospital

Field: Medicine (Health Sciences)

Objective : To determine the common causative bacterial agents of neonatal sepsis and their antimicrobial susceptibility in NICUMethods : Newborns with clinical signs of septicemia and positive blood culture during twelve months were prospectively studied. Samples for blood cultures, complete blood count, C-reactive protein, sugar, electrolytes were obtained ; ampicillin and gentamycin were started empirically.Result : Seven hundred and three neonates were investigated to rule out of sepsis. The male, female ratio was 1.3:1 and 56(63.63%) of patients were preterm and 32(36.36%) were term neonates. There were 68 (77.27%) cases of Early onset neonatal sepsis (EONS) and 20(22.64%) of Late onset neonatal sepsis (LONS). Coagulase negative staphylococcus (CONS) was the most common 37(42.04%) Gm+ve pathogen causing early onset neonatal sepsis and Acinetobacter was common Gm-ve pathogen in both early onset 16(18%) and late-onset 8 (9%) sepsis. CONS sepsis showed high degree of resistance to commonly used antibiotics; ampicillin (86.5%), oxacillin (60%),cefotaxime (67%) but comparatively low resistance to vancomycin (0%), gentamicin (25%), Levofloxacin(36%) & Imipenem (49%). Acinetobacter were highly resistant to ampicillin (100), gentamicin(75%), cefotaxime(100) and sensitive to Amikacin (58.33%), ciprofloxacin (54.16%), Levofloxacin and Imipenem (62.5%)and Colistin (95.83%).Conclusion : Neonatal sepsis in our NICU is mainly caused by grampositive organisms, which are developing resistance to commonly used antibiotics. The initial empirical choice of Ampicillin and Gentamicin appears to be unreasonable for our environment.Northern International Medical College Journal Vol.5(1) 2013: 297-300
Comparison of coil combination technique performance for phase preservation

Field: Medicine (Health Sciences)

MRI images are typically acquired using multiple receive coils, which introduce spatially varying phase offsets to each coil image. Many techniques have been developed to combine these coil images. For a variety of reconstruction techniques, phase preservation is necessary post-combination but it is unclear which method best achieves this. This work compared ESPIRiT, Simple Phase RCC, Full Phase RCC, 3T Siemens’ Adaptive Combine and IMPA using phase-cycled bSSFP images. Phase preservation was evaluated using the elliptical signal model theory and characteristic bSSFP phase plots. ESPIRiT consistently produced combined images with phase characteristics most similar to those from a single coil.
Chronic pelvic pain and dysfunction : practical physical medicine : towards an ecology of occupation-based practices

Field: Health Professions (Health Sciences)

* An Introduction to Chronic Pelvic Pain & Associated Symptoms * The Anatomy of Pelvic Pain * Chronic Pain Mechanisms * Psychophysiology and Pelvic Pain * Gender and Chronic Pelvic Pain * Musculoskeletal Causes and the Contribution of Sport to the Evolution of Chronic Lumbo-Pelvic Pain * The Role of Clinical Reasoning in the Differential Diagnosis and Management of Chronic Pelvic Pain * Multispeciality and Multidisciplinary Practice - a UK Pain Medicine Perspective * Multispeciality and Multidisciplinary Practice - a US Physical Medicine Perspective * Chronic Pelvic Pain and Nutrition * Breathing and Chronic Pelvic Pain: Connections and Rehabilitation Features * Biofeedback in the Diagnosis and Treatment of Chronic Essential Pelvic Pain Disorders * Soft Tissue Manipulation Approaches to Chronic Pelvic Pain (External) * Connective Tissue and the Pudendal Nerve in Chronic Pelvic Pain * Evaluation and Pelvic Floor Management of Urologic Chronic Pelvic Pain Syndromes * Practical Anatomy, Examination, Palpation and Manual Therapy Release Techniques for the Pelvic Floor * Patients with Pelvic Girdle Pain - An Osteopathic Perspective * Intramuscular Manual Therapy: Dry Needling * Electrotherapy and Hydrotherapy in Chronic Pelvic Pain
Comparison of laparoscopic enclosed electromechanical morcellation and vaginal enclosed scalpel morcellation at laparoscopic myomectomy: A prospective randomized trial

Field: Medicine (Health Sciences)

Abstract Aim This study aimed to compare the laparoscopic‐enclosed electromechanical morcellation (LEM) with vaginal‐enclosed scalpel morcellation (VSM) in laparoscopic myomectomy procedures. Methods One hundred eighteen patients who underwent laparoscopic myomectomy were enrolled the prospective randomized interventional clinical study in tertiary university hospital. After myomectomy, tissue removal was accomplished via either LEM using the in‐glove morcellation technique or VSM. Results The median tissue removal time was longer in the LEM group (25 min [range: 14–55]) than the VSM group (20 min [range: 6–38] [ p = 0.001]). Rescue analgesia requirement was significantly higher in the LEM group than the VSM group (mean rank: 56.92 vs. 40.92 doses, respectively; p < 0.001). There was no significant difference between preoperative and postoperative third month total scores of female sexual function index (FSFI) and subdomains in the LEM group. Conversely, all subdomains and total scores of FSFI (26.5 [16.7–34.8] vs. 22.7 [15.2–28.7]) except pain significantly worsened 3 months after operation in the VSM group. Conclusions LEM was associated with a longer tissue removal time and increased postoperative analgesic requirement. On the other hand, VSM was associated with worsened postoperative sexual function from baseline.
Assessment of Nonverbal Cognitive Processes in Children with Attention Deficit Hyperactivity Disorder

Field: Psychology (Social Sciences)

This study reviewed the literature on ADHD/ADD including a survey of the disorder, current clinical interventions and, diagnostic techniques. Data was collected comparing three groups of children (control, ADHD, ADD) on a newly developed nonverbal assessment test, the Leiter-R. The findings show that the Leiter-R resulted in significant differences in scores between the control group and the ADHD and ADD groups on twelve of the twenty subtests. This demonstrates the efficacy of the Leiter-R as an assessment tool for ADHD and ADD. Based on these findings the following tentative recommendations were proposed to assist children with ADHD and ADD. Children with ADHD and ADD need to have assistance with cognitive deficits as well as with behavioral problems. Children with ADHD and ADD may learn better when material is presented visually rather than in oral form only. Affected children may need to be taught problem solving skills because they have trouble generalizing from one situation to another. Research with children with Traumatic Brain Injury (TBI) has led to the development of teaching strategies that may be helpful with children with ADHD and ADD.
Synthesis of Vertically Aligned Helical Polyacetylene Films in Homeotropic Chiral Nematic Liquid Crystals

Field: Chemistry (Physical Sciences)

Abstract Vertically aligned helical polyacetylene thin films were synthesized by adding a chiral dopant into homeotropic nematic LC solvent to induce chiral nematic phase with homeotropic orientation. A scanning electron microscope (SEM) measurements showed that twisted polyacetylene fibrils are grown along the direction of film thickness, giving vertically aligned helical fibrillar morphology.
Prevalence and Longitudinal Trends of Food Allergy During Childhood and Adolescence: Results of the Isle of Wight Birth Cohort Study

Field: Medicine (Health Sciences)

D Venkataraman, M Erlewyn-Lajeunesse, RJ Kurukulaaratchy. Clin Exp Allergy. 2018;48(4):394–402

To determine prevalence and time trends in food allergy (FA) from birth to 18 years of age in an unselected birth cohort.

The Isle of Wight birth cohort was established in 1989, with 1536 enrollees, and has been observed prospectively for 18 years. This cohort has been used to study the natural history of allergic disease …
[West Nile arbovirus antibodies with hemagglutination inhibition (HI) in residents of Southeast Anatolia].

Field: Medicine (Health Sciences)

937 sera collected from different persons in Southeast Anatolia were studied for antibodies against West Nile - Virus by HI test. 763 out of 937 sera were from the research area, 42 from the neighboring districts and 21 from soldiers recently come to the research area, the features of the remaining 111 sera, except the ages of 4 could not be recorded. In the sera from the research area the West Nile antibodies were positive in 41.80%. The positive ratios were 40.49% in Diyarbakir, 47.83% in Mardin, 44.82% in Siirt, 38.09% in Urfa and 41.17% in Elâziğ. In 916 sera, the positive ratio was 40.06%. The ratio increased with the age, 5 out of 21 sera from soldiers were positive. It seems that in research area an active West Nile virus or a closely related one is found. We think that in neighboring areas some active foci of West Nile wirus are found.
Abstract 3156: Construction and validation of an activating and inhibitory chimeric antigen receptor (CAR) system

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Introduction: Chimeric antigen receptors (CARs) consists a promising type of adoptive immunotherapy. CARs consist of an antigen recognition unit (scFv), a transmembrane (TM) region and an intracellular activation domain. However, on target/off tumor responses due to target recognition in normal cells limits the widespread application of this therapy. In B-cell precursor acute lymphoblastic leukemia, lymphocytes expressing anti-CD19 CARs (19BBz) are being used in the clinical setting. However, the expression of CD19 as a pan-B marker can lead to undesired side effects such as depletion of mature B cells. As mature B cells express both CD19 and CD20 antigens, we propose the creation of an inhibitory anti-CD20 CAR, that when used in combination with 19BBz would be able to discriminate between leukemic blasts and normal B cells. Methods and results: Three inhibitory CARs were constructed containing signaling domains of CTLA-4, PD-1 or BTLA. Jurkat T cells expressing the plasmid pGL4.30 - expressing luciferase controlled by a NFAT responsive promoter - were generated. K562 cell line was used as target cells and modified to express CD19 (K5-19), CD20 (K5-20) or CD19 and CD20 (K5-19/20). In coculture experiments, Jurkat cells expressing 19BBz showed induction of luciferase activity when cultured with K5-19 or K5-19/20. However, Jurkat expressing both activation and inhibitory CAR showed inhibition of luciferase activity when incubated with K5-19/20 while maintained high activity when cultured with K5-19 cells. Furthermore, all three inhibitory CARs were able to inhibit the expression of the activation marker CD69 induced by 19BBz. In primary human T lymphocytes, the 20PD1 CAR did not inhibit proliferation or cytotoxicity induced by 19BBz. Surprisingly, T cells expressing 19BBz and 20PD1 showed preferential lysis of NALM6 CD19+ CD20+ cells, suggesting that the addition of PD1 domain may increase T-cell function in specific contexts. This effect was partially reversed by using a mutant PD1 domain where the tyrosines were replaced by phenylalanine and was completely reversed by using an anti-CD20 CAR truncated at the TM region, suggesting that this phenomenon is dependent of signaling. Conclusions: Additional experiments are needed to evaluate the activity of 20PD1 in primary human T cells. Experiments with inhibitory CARs 20LAG3 and 20PD1LAG3 are ongoing and can serve as an alternative to CAR 20PD1 in the construction of a conditional response system. Citation Format: Leonardo Chicaybam, Martin H. Bonamino. Construction and validation of an activating and inhibitory chimeric antigen receptor (CAR) system. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Res 2015;75(15 Suppl):Abstract nr 3156. doi:10.1158/1538-7445.AM2015-3156
Pharmacokinetics and pharmacodynamics of turoctocog alfa and N8-GP in haemophilia A dogs

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The objective of the present study was to evaluate the pharmacokinetic (PK) and pharmacodynamic (PD) profiles of the new recombinant FVIII compound turoctocog alfa and a Glyco-PEGylated FVIII derivative thereof (N8-GP) in Haemophilia A dogs. Six haemophilic dogs divided into two groups were included in the study. Each dog was administered a dose of 125 U kg−1, blood samples were collected at predetermined time points for both pharmacokinetic (FVIII measured by one-stage aPTT assay) and pharmacodynamic [whole blood clotting time (WBCT)] evaluations. After intravenous administration to haemophilic dogs, the plasma concentration at the first sampling point was comparable for turoctocog alfa and N8-GP, and the clearance was estimated to be 6.5 and 3.9 mL h−1kg−1 for turoctocog alfa and N8-GP respectively. Both turoctocog alfa and N8-GP were able to reduce the WBCT time to normal levels (<20 min), however, the reduced clearance was reflected in the WBCT, which returned to baseline at a later time point for N8-GP as compared with dogs dosed with turoctocog alfa. The clearance was 40% reduced for N8-GP as compared with turoctocog alfa. Simulations of a multiple dosing regimen in dogs, suggest that to maintain WBCT <20 min N8-GP can be dosed at reduced intervals, e.g. with 4 days between doses, whereas turoctocog alfa will have to be dosed with 2½ day between doses. Data thereby supports N8-GP as an alternative to standard rFVIII replacement therapy, with a more convenient dosing regimen.
Identification of some Gnetum spp. (Gnetaceae) in Southern Vietnamese by DNA barcode

Field: Agricultural and Biological Sciences (Life Sciences)

Gnetum is a tropical forest gymnosperm genus with about 47 species [1] are accepted by ‘The Plant list’, [1] and distribute in tropical forest around the world. In Vietnam, there are about 9 species and varieties are recorded. However, some of them were not included in ‘The Plant List’. Some are medicinally used in Vietnamese traditional medicine. Recent chemical and bioactivity studies on some of them revealed interesting results for future applications in health care. In Southern Vietnam, Gnetum gnemon L. var griffithii Markgr., Gnetum gnemon L. var tenerum Markgr.,Gnetum macrostachyum Hook.f., Gnetum leptostachyum Blume var. elongatum Markgr., Gnetum leptostachyum Blume var. latifolium Markgr., Gnetum latifolium Blume var. funiculare (Bl,) Markgr., Gnetum macrostachyum Hook f., Gnetum montanum Gnetum montanum Makrg. var macrocarpum Makgr. are recorded [2].
A tournament of transformation models: B-Spline-based vs. mesh-based multi-objective deformable image registration

Field: Computer Science (Physical Sciences)

<p>The transformation model is an essential component of any deformable image registration approach. It provides a representation of physical deformations between images, thereby defining the range and realism of registrations that can be found. Two types of transformation models have emerged as popular choices: B-spline models and mesh models. Although both models have been investigated in detail, a direct comparison has not yet been made, since the models are optimized using very different optimization methods in practice. B-spline models are predominantly optimized using gradient-descent methods, while mesh models are typically optimized using finite-element method solvers or evolutionary algorithms. Multi-objective optimization methods, which aim to find a diverse set of high-quality trade-off registrations, are increasingly acknowledged to be important in deformable image registration. Since these methods search for a diverse set of registrations, they can provide a more complete picture of the capabilities of different transformation models, making them suitable for a comparison of models. In this work, we conduct the first direct comparison between B-spline and mesh transformation models, by optimizing both models with the same state-of-the-art multi-objective optimization method, the Multi-Objective Real-Valued Gene-pool Optimal Mixing Evolutionary Algorithm (MO-RV-GOMEA). The combination with B-spline transformation models, moreover, is novel. We experimentally compare both models on two different registration problems that are both based on pelvic CT scans of cervical cancer patients, featuring large deformations. Our results, on three cervical cancer patients, indicate that the choice of transformation model can have a profound impact on the diversity and quality of achieved registration outcomes.</p>
Preparation by the Canadian Ice Service for the Operational Use of the RADARSAT Constellation Mission in Their Ice and Oil Spill Monitoring Programs

Field: Earth and Planetary Sciences (Physical Sciences)

. The Canadian Ice Service (CIS) has successfully used airborne and spaceborne synthetic aperture radar (SAR) data extensively for almost three decades in their daily ice and oil monitoring operations. Microwave radar's unique ability to penetrate clouds and weather make these types of data invaluable to the CIS's support to efficient environmental stewardship and safe operations in Canadian waters. Canada's RADARSAT-1 and RADARSAT-2 platforms have been used by CIS since 1996, with approximately 70,000 image scenes incorporated into the development of operational products in that time. The next generation of the RADARSAT program, the RADARSAT Constellation Mission (RCM), will provide C-band SAR data continuity for CIS and other Canadian SAR users for many years to come when launched in 2018. The RCM will consist of a three satellite constellation, offering improved coverage and new technological advancements, and will provide CIS with a unique opportunity to develop new and improved ice and oil information products. This technical note will discuss the prelaunch preparations planned at the CIS that will enable its operational programs to effectively use the capabilities afforded by this mission at launch and beyond.Résumé. Le Service canadien des glaces (SCG) a abondamment utilisé avec succès des données de radars à synthèse d'ouverture spatiaux et aéroportés pendant près de trois décennies dans leurs opérations quotidiennes pour la surveillance des glaces et de la pollution pétrolière. La capacité unique des micro-ondes radar à traverser les nuages et les conditions météorologiques adverses rend ces types de données précieuses au SCG pour appuyer une gestion efficace de l'environnement et la sécurité des opérations dans les eaux canadiennes. Les plateformes RADARSAT-1 et RADARSAT-2 du Canada ont été utilisées par le SCG depuis 1996 et, jusqu'à présent, environ 70 000 images ont été incorporées dans le développement de produits opérationnels. Lors de son lancement en 2018, la prochaine génération du programme RADARSAT, la mission de la Constellation RADARSAT (MCR), assurera la continuité des données SAR en bande C pour le SCG et les autres utilisateurs canadiens de données SAR pour de nombreuses années à venir. La MCR sera composée d'une constellation de trois satellites, offrant une meilleure couverture, de nouvelles avancées technologiques, et elle fournira au SCG une occasion unique de développer de nouvelles et meilleures informations sur les glaces et la pollution pétrolière. Cette note technique discute des préparatifs de prélancements qui sont prévus au SCG et qui permettront à ses programmes opérationnels d'utiliser efficacement les capacités offertes par cette mission au moment du lancement et au-delà.
In Situ Construction of Cobalt-Doped High-Dispersive Heazlewoodite for Efficient Oxygen Evolution

Field: Chemistry (Physical Sciences)

Water electrolysis to produce hydrogen has been considered the most potential strategy in the renewable energy area but is restricted by the sluggish kinetics at the anode oxygen evolution. In this work, we design and construct cobalt-doped heazlewoodite (Co–Ni3S2) catalysts via a simple one-step in situ sulfurization strategy. The Co–Ni3S2 spheres are fixed on a nickel foam (NF) substrate with a high-dispersive property. The replacement reaction between Co2+ and the NF substrate has taken place with the assistance of a sulfur resource, resulting in cobalt doping in the Ni3S2 spheres. In terms of the oxygen evolution reaction (OER) activity and reaction kinetics of the catalysts, Co–Ni3S2 plays the highest OER performance, which is mainly ascribed by the Co dopants in tuning the morphology and intrinsic properties of the catalyst. In combination of the superior electrochemical stability, Co–Ni3S2 would be a potential candidate in practical industrial water electrolysis.
Analysis of Flow Patterns in High‐Gravity Equipment Using Gamma‐Ray Computed Tomography

Field: Chemical Engineering (Physical Sciences)

Abstract The capacity of today's gas‐liquid contacting equipment such as tray or packed columns is limited by the gravitational‐driven liquid flow. Intensified equipment applying centrifugal force offers great potential for enhancing the mass transfer and for reducing equipment size. Yet, detailed knowledge about the liquid flow inside rotating packings is scarce due to limited accessibility with conventional measurement systems. In this study, a gamma‐ray computed tomography is employed to quantify the liquid hold‐up and its distribution in the moving packing.
Mayotte: France's New Overseas Department in the Indian Ocean

Field: Arts and Humanities (Social Sciences)

Mayotte (Maore), the easternmost island in the Comoros archipelago, took a tremendous political leap in 2009 by voting to become, in 2011, France's 101st département. Many teachers of French are unfamiliar with Mayotte and its integration into la République française. The present article introduces readers to the island's geography and history, Mahorais society, and its indigenous languages. The article concludes with suggested resources for including Mayotte in the classroom.