jimnoneill/paper-to-field-training huggingface dataset:
Community‐based oral health promotion practices targeted at children and adolescents in Finland – developing an assessment tool

Field: Health Professions (Health Sciences)

Abstract Objectives To develop an assessment tool for evaluating oral health promotion practices and to evaluate community‐based oral health promotion practices targeted at children and adolescents with this tool. Methods A theoretical framework about health promotion planning, implementation and evaluation was made on the basis of a literature review. Then, information about Finnish community‐based oral health promotion practices ( n = 12) targeted at children and adolescents was collected using semi‐structured interviews. Also, related documents, for example action plans and reports, were collected when available. Next, an assessment tool based on the theoretical framework was developed, and the recorded and transcribed interview data and other documents were evaluated with this tool. Results The assessment tool proved to be practical: it pointed out the strengths and weaknesses of the practices. The tool revealed strengths in the implementation and deficiencies in the planning and evaluation of oral health promotion practices. One‐quarter of the 12 practices assessed could be considered ‘good practices’. Conclusions There is a need to improve the planning and evaluation of oral health promotion practices. The assessment tool developed in this study might be useful for practitioners both in the field of oral health promotion and general health promotion.
Media Effects: Marshall McLuhan, Television Culture, and "The X-Files"

Field: Arts and Humanities (Social Sciences)

Research Article| July 01 1998 Media Effects: Marshall McLuhan, Television Culture, and "The X-Files" Adrienne L. McLean Adrienne L. McLean Search for other works by this author on: This Site PubMed Google Scholar Film Quarterly (1998) 51 (4): 2–11. https://doi.org/10.2307/1213239 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Adrienne L. McLean; Media Effects: Marshall McLuhan, Television Culture, and "The X-Files". Film Quarterly 1 July 1998; 51 (4): 2–11. doi: https://doi.org/10.2307/1213239 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentFilm Quarterly Search This content is only available via PDF. Copyright 1998 The Regents of the University of California Article PDF first page preview Close Modal You do not currently have access to this content.
Rotated Morse curve–spline potential function for A+BC reaction dynamics: Application to (Cl, HBr), (F,H2), and (H+,H2)

Field: Chemistry (Physical Sciences)

Methods for the fitting of potential energy functions to discrete potential energy data for triatomic molecules are discussed. Several new criteria for successful fitting functions are proposed, and existing criteria are reviewed. Different semiempirical and empirical fitting functions are analyzed in terms of these criteria. The rotated Morse curve–spline (RMCS) method is developed for general triatomic molecules, and applied to the systems Cl+HBr, F+H2, and H++H2. The detailed surface features are well reproduced for Cl+HBr and F+H2, particularly near the minimum energy path. Overall standard deviations between reference functions and RMCS functions are 0.98 and 0.35 kcal/mole for Cl+HBr and F+H2, respectively. Averaged classical trajectories on the F+H2 surface show good agreement between LEPS and RMCS surfaces over the range 0–10 eV, although there is no point-for-point matching of individual trajectories. Relative CPU times for trajectories on the RMCS and LEPS surfaces are 3.3:1. A H+3 potential surface is obtained by the combined use of CNDO/2 energy data and the RMCS fitting function. The resulting surface is scaled to ab initio data by adjustment of the spline functions. It gives a realistic representation of the ab initio surface, except that nonphysical behavior occurs in the outer contours (this was also true for Cl+HBr). The problem of discontinuities arising from the bond angle–bond distance coordinate system is discussed. Possible extensions and limitations of the RMCS method are considered. When Morse curves can describe the asymptotic dissociation channels for A+BC reactions, the RMCS method provides an accurate interpolating function for triatomic potential energy data. Its suitability for classical and quantal studies of reaction dynamics for A+BC systems depends on the magnitude of the discontinuity problem. Computational procedures to study this problem in advance of and during classical trajectories, are given and discussed in detail for F+H2.
[Heparin-aspirin complex, its physico-chemical and physiologic properties].

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

A method is developed for isolation of fibrinolytic and anticoagulant complex heparin-aspirin. The complex possessed the highest activity when the ratio of heparin to aspirin was 10 : 1. In vitro and in vivo the complex obtained showed high anticoagulant and fibrinolytic activity with respect to unstabilized fibrin both in absence and in presence of epsilon-aminocaproic acid as well as it had the thrombolytic effect on the fresh thrombus. The total fibrinolytic activity, nonenzymatic fibrinolysis and the anticoagulation activity in blood plasma were increased after chronic administration per os and after repeated intramuscular administration of the complex. The most distinct increase in fibrinolytic properties of blood occurred after intravenous administration of the heparin-aspirin complex.
Factors Influencing Job Satisfaction Among Employees: A Case Study of Hotel Taiping Perdana

Field: Business, Management and Accounting (Social Sciences)

This study was conducted to gain view on the issue of job satisfaction in a Hotel Taiping Perdana among the employees. The main purpose of this study is to determine relationship between pay, supervision, work itself, work conditions, promotion opportunities and job satisfaction. The dependent variable is job satisfaction while the independent variables are pay, supervision, work itself, work conditions, promotion opportunities. This study is conducted through quantitatively method where data is collected using a set of questionnaire.Survey questionnaires were used in order to obtain feedback from respondents. Samples of this research were the employees of Hotel Taiping Perdana where a total of 68 respondents (85 percent) took part in the survey.The findings show that there is a positive significant relationship between pay,supervision,work conditions, promotion opportunities and job satisfaction. This show,employees feel satisfied when they worked at Hotel Taiping Perdana. The study provides a better understanding regarding the factors affecting job satisfaction in hotel industry.Thus,it emphasizes that there is still a need to conduct additional research to filling the gaps that not been solved in the current study. The findings of this study is of immerse benefits to the Hotel Taiping Perdana and will enable to gain better competitive advantage to be able to compete among local and international hotel. Since the findings will assist the hotel organization to know the best way of satisfying their employees. Furthermore, in the final chapter, some recommendations were provided for future use to any researcher in this academic field.
Shifting beliefs and practices on translanguaging in an online master’s programme

Field: Arts and Humanities (Social Sciences)

The purpose of this article is to present action research on translanguaging beliefs and practices in an online graduate education programme. The focal course is a master’s programme in an English-medium university in Kazakhstan, a country with two official languages (Kazakh and Russian), a trilingual education policy to develop proficiency in English alongside Russian and Kazakh, and a history of mixing Russian and Kazakh languages. The focal course shifted to an online teaching mode in Fall 2020 due to the Covid-19 crisis. The author has analysed data from a Zoom recording of a class lecture and a post-course anonymous survey to identify students’ beliefs and shifts in beliefs, along with influences on those beliefs. The findings suggest there are a constellation of influences online and offline that contribute to the positions and movement of student beliefs along different continua about translanguaging. One unique online contribution may be workshops and seminars in distant locales that might not otherwise be accessible for students face-to-face. Regardless of modality, providing active models of pedagogical translanguaging is recommended in future professional development courses.
Exotic grasses and nitrate enrichment alter soil carbon cycling along an urban–rural tropical forest gradient

Field: Environmental Science (Physical Sciences)

Abstract Urban areas are expanding rapidly in tropical regions, with potential to alter ecosystem dynamics. In particular, exotic grasses and atmospheric nitrogen (N) deposition simultaneously affect tropical urbanized landscapes, with unknown effects on properties like soil carbon (C) storage. We hypothesized that (H1) soil nitrate ( NO 3 − ) is elevated nearer to the urban core, reflecting N deposition gradients. (H2) Exotic grasslands have elevated soil NO 3 − and decreased soil C relative to secondary forests, with higher N promoting decomposer activity. (H3) Exotic grasslands have greater seasonality in soil NO 3 − vs. secondary forests, due to higher sensitivity of grassland soil moisture to rainfall. We predicted that NO 3 − would be positively related to dissolved organic C ( DOC ) production via changes in decomposer activity. We measured six paired grassland/secondary forest sites along a tropical urban‐to‐rural gradient during the three dominant seasons (hurricane, dry, and early wet). We found that (1) soil NO 3 − was generally elevated nearer to the urban core, with particularly clear spatial trends for grasslands. (2) Exotic grasslands had lower soil C than secondary forests, which was related to elevated decomposer enzyme activities and soil respiration. Unexpectedly, soil NO 3 − was negatively related to enzyme activities, and was lower in grasslands than forests. (3) Grasslands had greater soil NO 3 − seasonality vs. forests, but this was not strongly linked to shifts in soil moisture or DOC . Our results suggest that exotic grasses in tropical regions are likely to drastically reduce soil C storage, but that N deposition may have an opposite effect via suppression of enzyme activities. However, soil NO 3 − accumulation here was higher in urban forests than grasslands, potentially related to of aboveground N interception. Net urban effects on C storage across tropical landscapes will likely vary depending on the mosaic of grass cover, rates of N deposition, and responses by local decomposer communities.
Edens d’acclimatation : l’utopie positiviste chez Honore de Balzac et Emile Zola

Field: Arts and Humanities (Social Sciences)

My dissertation deals with Utopian writing in Honore de Balzac's "Le Medecin de campagne" (1833) and Emile Zola's "Travail (1901). From a theoretical point of view, I argue that while it might seem contradictory for Realist or Naturalist authors to be writing Utopias, this type of fiction, with its highly axiomatized discourse and its will to grasp material norms, is in fact compatible with these authors' scientific and documentary aspirations. I suggest that prior to the refutation of positivism by logicians of science in the mid-1900s, the idea of separating «physics» from «metaphysics» haunted scientific and social thinking. The quest for this demarcation informs all attempts to characterize society in what I call positivist utopianism. In the case of Balzac, "Le Medecin de campagne" attempts to carry out a logical demonstration of the benefits associated with agrarian reforms achieved in a rural community on the eve of Louis Philippe's constitutional monarchy. Though the discourse on the village's economic and social rebirth is delivered in a largely deductive fashion, the premises - religious or liberal – of this axiomatisation are never made clear. In Zola's "Travail", the elaboration of the fictional community takes a different form. Here, the premise of social perfectibility is given, held to, and demonstrated quite consistently, save for a few problematic but meaningful exceptions. Indeed, the novel's predictability is such that the work's artistic merit came under fire at the time of its publication. By positioning the work in its historical context, I suggest that the very simplicity of its stance is highly polemic. Written in light of the Dreyfus affair and of Emile Poincare's scientific popularizing, the novel can be read as an exploration of the woes and freedom of trying to write "scientifically" while acknowledging that mere convention governs truth. I conclude that "Le Medecin de campagne" and "Travail", appearing at pivotal historical moments in post-Revolutionary France, herald social as well as scientific modernity. They yield a problematic representation of the social object whose existence in language and material reality both enables the Utopian project and frustrates it.
TRIPLE TEST CROSS ANALYSIS FOR GENETIC COMPONENTS OF SALINITY TOLERANCE IN SPRING WHEAT

Field: Agricultural and Biological Sciences (Life Sciences)

Soil salinity poses considerable and increasing problems for agriculture, and is receiving much attention from plant breeders. The identification of genes whose expression enables plants to adapt to and/or tolerate salt stress is essential for breeding programs, but little is known about the genetic mechanisms of traits in saline conditions. The data obtained from 75 families produced by crossing 25 F2 plants derived from a cross between two spring hexaploid wheats, namely Siete Cerros (salt tolerant) and Axona (salt sensitive), to their parents and their F1 progenies, was subjected to triple test cross analysis. The genetic components (epistasis, additive and dominance) and their interactions with the environment (control - salinity) were detected for heading date, days to maturity, final plant height, spike length, ear weight, straw weight, number of grains per ear, grain yield per plant, 1000 grain weight, whole plant weight and harvest index. Epistasis was presented only for days to maturity (‘j’ and ‘l’ types) and plant height (‘i’ type) at control and spike length (‘j’ and ‘l’ types) at salinity condition. Additive component (D) was more important than dominance (H) especially in salinity condition. Dominance ratio, ( H /D) 1/2 , was less than unity in both environments and heritability (h 2 ) decreased for all traits at salinity condition.
Metabolite Identification of a Radiotracer by Electrochemistry Coupled to Liquid Chromatography with Mass Spectrometric and Radioactivity Detection

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Radioligands, which specifically bind to a receptor or enzyme (target), enable molecular imaging of the target expression by positron emission tomography (PET). One very promising PET tracer is (S)-1-(4-(2-[(18)F]-fluoroethoxy)benzyl)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin (isatin), a caspase-3 inhibitor, which has been developed at the University Hospital of Münster to image cell death (apoptosis). The translation of this novel tracer from preclinical evaluation to clinical examinations requires biodistribution studies, which characterize the pharmakodynamics and metabolic fate of the compound. This information is used to further optimize the radioligands and to interpret radioactive signals from tissues upon injection of the radioligand in vivo with respect to their specificity. The analysis of the metabolism of radioligands is hampered by the low amount of the compound being typically injected (nano/picomolar amount per injection). In the present study, electrochemistry (EC) is applied to elucidate the oxidative metabolism pathway of the radiotracer. Previous studies have demonstrated that EC can be utilized as a complementary tool to conventional in vitro approaches in drug metabolism studies. Thereby, potential oxidative metabolites of the isatin are determined by EC coupled to electrospray ionization mass spectrometry (EC/ESI-MS). Moreover, using EC/liquid chromatography (LC) and ESI-ion trap MS(n), structural elucidation of the oxidation products is performed. Comparatively to EC, in vitro metabolism studies with rat liver microsomes are conducted. Finally, the developed LC/ESI-MS method is applied to determine metabolites in body fluids and cell extracts from in vivo studies with the nonradioactive ((19)F) and radioactive isatin ((18)F). On the basis of the electrochemically generated oxidation products of the radioligand, the major radioactive metabolite occurring in vivo was successfully identified.
Foot Macrodactyly Associated with Klippel-Trenaunay Syndrome

Field: Medicine (Health Sciences)

Klippel-Trenaunay syndrome is a rare congenital malformation which may be associated with macrodactyly. The main problem is the need for custom-made shoes. We describe the case of a female newborn affected by Klippel-Trenaunay syndrome, with a larger and longer right foot; the difference increased progressively and, at 5 years of age, the right foot was 50% larger and 38% longer than the left one. Due to the progression of the deformity, reduction surgery was advised to reduce the foot’s width. Resection of the second ray and 2nd cuneiform was performed. The result was excellent and there were no complications during a 10-year follow-up period with a decrease of width and length difference to 10% and 4%, respectively, in comparison to the contralateral foot. There were no gait anomalies. Abnormal foot width and length represented the main problems and guided the surgical strategy. Second ray resection was effective, without complications and with a good long-term functional outcome. Possibility of wearing fashionable conventional shoes without insoles was achieved to the patient’s satisfaction
Characterization of cancer stem-like cells in a novel STI571-resistant chronic myeloid leukemia cell line

Field: Medicine (Health Sciences)

描绘房间衬里的新奇长期的 myeloid (电流型逻辑) 并且进一步阐明的目的到 STI571 的抵抗的机制。一个新奇 K562 房间衬里的方法(K562/VP16 ) 在 K562 房间的暴露以后被完成到 VP16。能够在 K562/VP16 房间线排除 Hoechst 33342 的一张小潜水艇人口(K562/VP16 SP ) 被排序的流动血细胞计数孤立。K562/VP16 房间的其余部分作为 non-SP K562/VP16 被分类。涉及对 STI571 变得抵抗的 K562/VP16 SP 房间的机制被学习。结果 Bcr-Abl 和 Abl 蛋白质的层次在 K562 房间线并且在 non-SP K562/VP16 和 K562/VP16 SP 房间是类似的。multidrug 抵抗的基因 1 (MDR1 ) 170 kDa P-glycoprotein (P-gp ) 的表示在 K562/VP16 non-SP 和 K562/VP16 SP 房间然而并非在 K562 房间被检测。在二根 K562/VP16 房间线的 P-gp 的表示层次是类似的。与 non-SP K562/VP16 相比， K562/VP16 SP 房间对 STI571 更抵抗。这个电阻几乎不能被许多多颠倒药抵抗禁止者。另外，在活体内学习证明 K562/VP16 SP 房间在老鼠导致了肿瘤发生，当 K562/VP16 non-SP 房间没能那么做时。结论 A 小说 K562 房间线， K562/VP16，被产生。小方面人口 K562/VP16 SP 房间，到 STI571 处理的有的高抵抗和比 K562 房间的更多的致瘤的。它可以代表 K562/VP16 房间线的癌症干细胞。
Studies of Fatigue Crack Bent and Growth from a Slanted Crack. Noting Discontinuous Displacement along a Crack and the Resulting Stress Intensity Factors.

Field: Engineering (Physical Sciences)

By using slanted pre-crack specimens, fatigue crack growth under a mixed- mode condition was discussed within the scope of linear fracture mechanics. The discontinuous displacement measured along the pre-crack with an angle β=30 deg. between the crack and the axis of tension was smaller than the theoretical value. This discrepancy suggests the contact of the crack surfaces under a large relative slip displacement. The measured fatigue fracture angles agreed well with the values calculated based on the maximum tangential stress criterion, using the effective stress intensity factors (Mode I, II) estimated from the discontinuous displacement along the pre-crack.For the bent crack formed after fatigue crack initiation from the pre-crack, the path of the fatigue crack growth was mainly dominated by a mode I discontinuous displacement component on the measurement. A method was described in which the bent crack was converted into a straigth crack in a vector form of the discontinuous displacement along the crack. Using this method, the stress intensity factors (Mode I) of the bent crack were evaluated. They were in good agreement with the theoretical values except the case of the heavy contacts between the crack surfaces.
Abstract 4465: Targeted disruption of HDAC3 induces terminal myogenic differentiation of embryonal rhabdomyosarcoma

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Embryonal rhabdomyosarcoma (ERMS), one of the most common and lethal pediatric sarcomas, is characterized by an arrest in myogenic differentiation. We have previously shown that treatment of ERMS cells with pan histone deacetylase (HDAC) inhibitors promotes myogenic differentiation. However, the underlying mechanism specific to each HDAC in ERMS remains unknown. We have completed a high-efficiency CRISPR/Cas9 gene knockout screen of class I and II HDAC genes, revealing HDAC3 as a major driver of myogenic suppression in ERMS. HDAC3-deficient ERMS cells showed robust terminal myogenic differentiation with the formation of multinucleated myotubes. Expanding on our in vitro studies, we developed a novel tamoxifen-inducible CRISPR gene-targeting system in ERMS xenografts established in immune-compromised mice. Disruption of HDAC3 in vivo significantly suppressed tumor growth by inducing myogenic differentiation of ERMS cells. By combining inducible CRISPR gene targeting with HDAC3 structure-function analysis, we showed that HDAC3 functions in concert with the nuclear receptor co-repressor (NCOR1 and NCOR2) complex to regulate gene transcription. HDAC3/NCOR binding and HDAC3 deacetylase activity are both required for suppressing myogenic differentiation in ERMS. RNA sequencing analysis of differentially expressed genes in HDAC3-deficient ERMS cells highlighted key pathways dysregulated in ERMS. Our results suggest that epigenetic silencing of the myogenic program is a major mechanism required for ERMS tumor growth. Identification of the essential interaction between HDAC3 and the NCOR transcriptional repressor complex as well as downstream genes and pathways provides important insights into the biology of ERMS tumorigenesis. Our findings highlight potential new drug targets specific to the activity of HDAC3 in order to improve treatment of ERMS patients. Citation Format: Michael Phelps, Jenna Bailey, Terra Vleeshouwer-Neumann, Eleanor Chen. Targeted disruption of HDAC3 induces terminal myogenic differentiation of embryonal rhabdomyosarcoma. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 4465.