jimnoneill/paper-to-field-training huggingface dataset:
8 The Pentateuchal Targums in Rabbinic Literature

Field: Arts and Humanities (Social Sciences)

This remarkable survey introduces critical knowledge and insights that have emerged over the past forty years, including targum manuscripts discovered this century and targums known in Aramaic but only recently translated into English. Prolific scholars Flesher and Chilton guide readers in understanding the development of the targums; their relationship to the Hebrew Bible; their dates, language, and place in the history of Christianity and Judaism; and their theologies and methods of interpretation.
ESPACOMP Medication Adherence Reporting Guideline (EMERGE)

Field: Health Professions (Health Sciences)

Research on assessing or managing medication adherence applies approaches from observational, interventional, and implementation science that spans many disciplines and demands coherent conceptualization, valid methods, appropriate analyses, and complete and accurate reporting. To ensure such reporting, the European Society for Patient Adherence, COMpliance, and Persistence (ESPACOMP) Medication Adherence Reporting Guideline (EMERGE) recommends standard reporting approaches based on an accepted taxonomy. This guideline is derived from a literature review, a reactive Delphi study with 26 medication adherence experts from many countries and disciplines, and feedback from ESPACOMP members. It is designed to supplement existing guidelines for health research reporting and is structured around 4 minimum reporting criteria and 17 items reflecting best reporting practice. By enhancing and harmonizing research reporting, EMERGE aims to advance research and, ultimately, patient outcomes.
Estimating the Effect of Influenza Vaccination on Nursing Home Residents’ Morbidity and Mortality

Field: Medicine (Health Sciences)

Objectives To estimate the effect of influenza vaccination on hospitalization and mortality in nursing home ( NH ) residents. Design Retrospective cohort study. Setting Medicare claims data linked to NH Minimum Data Set assessments and Centers for Disease Control and Prevention ( CDC ) surveillance data from 122 U.S. cities. Participants More than 1 million Medicare fee‐for‐service, long‐stay NH residents between 2000 and 2009. Measurements Weekly facility outcome aggregates of NH resident pneumonia and influenza (P&I) hospitalizations and all‐cause mortality and city‐level P&I mortality as reported by the CDC were created. The seasonal vaccine match rate for influenza A/H1N1, A/H3N2, and B strains was calculated, and each outcome was compared in seasons of high and low match rates using facility fixed‐effects regression models separately for full‐year and nonsummer months. Results Average weekly all‐cause mortality varied across seasons from 3.74 to 4.13 per 1,000 NH residents per week, and hospitalization for P&I varied from 2.05 to 2.43. Vaccine match rates were invariably high for H1N1 but variable across seasons for the other two types. The association between vaccine match and reduction in overall mortality and P&I hospitalizations was strongest for A/H3N2, the influenza strain typically responsible for the most‐severe influenza cases. Given the approximately 130,000 deaths and 77,000 P&I hospitalizations of long‐stay NH residents during the 32 nonsummer weeks, the model estimated that a 50‐percentage‐point increase in the A/H3N2 match rate (from <25% to >75%) reduced long‐stay NH resident deaths by 2.0% and P&I hospitalizations by 4.2%. Conclusion Well‐matched influenza vaccine prevents P&I hospitalizations and mortality in NH residents.
Clinical Effect of Mirtazapine on 60 Cases of Generalized Anxiety Disorder

Field: Medicine (Health Sciences)

[Objective] To explore the clinical effect and adverse reactions of mirtazapine for generalized anxiety disorder(GAD).[Methods]60 GAD patients were randomly divided into two groups,which were treated by mirtazapine 15~45 mg/d and imipramine 50~150 mg/d respectively for 6 weeks.The clinical effect and adverse reaction were evaluated with Hamilton anxiety scale(HAMA) and treatment emergent symptom scale(TESS) before treatment and 1,2,4,6 weeks after treatment.[Results]The obvious effective rate of mirtazapine for GAD was 84.7%,and the effective rate was 100%.The obvious effective rate of imipramine was 66.7%,and the effective rate was 88.9%.There was no significant difference between two groups(P0.05).On aspect of adverse reaction,the TESS scores of mirtazapine group was significantly lower than that of imipramine group(P0.05).[Conclusion]Mirtazapine is a rapid,safe and effective drug for GAD.
Occurrence Download

Field: Earth and Planetary Sciences (Physical Sciences)

A dataset containing 0 species occurrences available in GBIF matching the query: { "and" : [ "TaxonKey is one of (Chiroptera)", "HasCoordinate is true", "HasGeospatialIssue is false", "Year is greater than or equal to 1980", "OccurrenceStatus is Present", { "not" : { "BasisOfRecord" : [ "is one of (Fossil, Living Specimen)" ] } }, "Geometry POLYGON((-180 -90,-150 -90,-150 -60,-180 -60,-180 -90))" ] } The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047928-250920141307145/datasets/export for details.
Medianavorsing in Suid-Afrika

Field: Social Sciences (Social Sciences)

Three main issues with regard to ‘Media research in South Africa’ at the moment are presented in this article, namely mat research findings represent power; that research findings are essential in changing societies such as the South African one in order to plan future communication programs; and that the education and training of media researchers is currently still fragmented and not sufficient These issues pose specific challenges to the field of media research within the South African society.
FLUKA simulations of radionuclide yields in oblique targets

Field: Physics and Astronomy (Physical Sciences)

In nuclear medicine radionuclides are used in diagnosis and therapy. They can be produced in cyclotrons with different nuclear reactions. Overall goal is the optimization of the yield of the desired radionuclide which is possible by changing different experimental parameters. To test the influence of these parameters to obtain an optimal yield, simulation programs like PHITS and FLUKA can be used. In first studies (see Klink et al. [Testing the suitability of FLUKA and PHITS to predict the outcome of radionuclide production. Radiat. Eff. Defects Solids 2023, 178 (1–2), 111–125]) the experimental yields of nuclide productions were compared with simulation results of different target designs with perpendicular and inclined configuration. In this paper we focus on the effect of inclination since it was one of the problematic cases of the previous study [Klink et al. Testing the suitability of FLUKA and PHITS to predict the outcome of radionuclide production. Radiat. Eff. Defects Solids 2023, 178 (1–2), 111–125]. Different beam profiles were varied in the simulations to determine its influence on the simulated yields. The choice of the beam profile has a great influence on simulating irradiations of inclined targets. With a known beam profile and other experimental conditions, FLUKA can be used to simulate nuclide productions of inclined targets with small deviations compared to the experimental yields. In conclusion, FLUKA can be used to determine the yield of unknown nuclide production with different target designs.
The Action of Adrenalin Chloride on the Human Heart

Field: Medicine (Health Sciences)

Journal Article The Action of Adrenalin Chloride on the Human Heart Get access W. E. Hume W. E. Hume Search for other works by this author on: Oxford Academic PubMed Google Scholar QJM: An International Journal of Medicine, Volume os-21, Issue 84, July 1928, Pages 459–462, https://doi.org/10.1093/qjmed/os-21.84.459 Published: 01 July 1928 Article history Received: 25 November 1927 Published: 01 July 1928
A Case of Floating Mural Thrombus Management in Abdominal Aortic Aneurysm Using Effective Echography

Field: Medicine (Health Sciences)

89歳女性。心房細動に対しDOACを内服していた。B型急性大動脈解離および腹部大動脈瘤（40 mm）の診断で緊急入院しDOACは中止した。入院後8日目に腹部大動脈瘤内に新規の浮遊血栓を認めたが，高齢，フレイルのため保存的加療とし血栓は3カ月で消失した。腹部大動脈瘤内の浮遊血栓は高感度ドップラーを併用した腹部超音波で低エコーとAC signが混在している場合，保存的加療を選択しえると考えられた。
Central charges of T-dual branes for toric varieties

Field: Mathematics (Physical Sciences)

Given any equivariant coherent sheaf L \mathcal {L} on a compact semi-positive toric orbifold X \mathcal {X} , its SYZ T-dual mirror dual is a Lagrangian brane in the Landau-Ginzburg mirror. We prove that the oscillatory integral of the equivariant superpotential in the Landau Ginzburg mirror over this Lagrangian brane is the genus-zero 1 1 -descendant Gromov-Witten potential with a Gamma-type class of L \mathcal {L} inserted.
Investigating the Effects of Manual Therapy and Pelvic Floor Training on Erectile Dysfunction: A Case Study

Field: Health Professions (Health Sciences)

Introduction: Erectile dysfunction (ED) is a common issue in men, often associated with various factors, such as obesity, diabetes, and more. This case study examines the impact of friction massage combined with pelvic floor exercises on ED in three patients, linked to prostatic adenectomy, aging, and diabetes. Case Description: Patients followed a one-month regimen of pelvic floor exercises and techniques. The technique’s progress was monitored via video calls twice a week. Exercises lasted for 10 min daily, along with a 10-min massage. We assessed improvement using the international index of erectile function 15 (IIEF15) questionnaire and erection hardness score (EHS), as well as ultrasound scans. Results: Following treatment, all three patients showed increased EHS and IIEF15 15 scores. Muscular thickness increased in the ischiocavernosus and bulbospongiosus muscles, while the cavernosal artery exhibited higher systolic velocity and lower diastolic velocity, although maximum blood flow velocity in the posterior vein decreased. Treatment had the most significant impact on the adenectomy patient, followed by the elderly patient and then the diabetic patient. Conclusion: Combining friction massage and pelvic floor exercises led to improved erection- related indicators and increased patient satisfaction.
[Glabrizoflavone--a novel isoflavone from Glycyrrhiza glabra L].

Field: Chemistry (Physical Sciences)

7-O-Methylglabranin, 6-C-prenylpinocembrin, glabranin, pinocembrin, galangin, and a novel isoflavonoid, (E)-5,7,4'-trihydroxy-6-(3-hydroxymethyl-2-butenyl)isoflavone (glabrisoflavone) were isolated from the aerial parts of Glycyrrhiza glabra L. The structure of the novel isoflavonoid was elucidated on the basis of chemical transformations and spectral data.
PHYSICAL FITNESS AND THE INCIDENCE OF FUNCTIONAL LIMITATION IN MEN AND WOMEN 604

Field: Medicine (Health Sciences)

This study examined the association of physical fitness with the incidence of functional limitation in 2,053 men and women (average age 59 years; range 46 to 77). Participants' fitness levels were classified into three categories with cut points of the lowest 20%, middle 40% and highest 40% of sex-age-specific stress time on a maximal treadmill test conducted between 1987 and 1990. Functional limitation was defined as having difficulty or could not perform household activities and daily activities in 1995. Average length of follow-up was 6.7 years (range: 6-8 years). Among participants who had no functional problem in 1990, 3.1% (64) reported functional limitations in 1995. Incidence of functional limitation was higher for women (6.2%) than for men(2.3%), higher among older (3.7%) than younger (2.5%) persons, and higher for the low fit group (7.5%) than moderate fit (2.8%) and high fit (1.3%) groups. The logistic model showed that high fit and moderate fit men had a risk of functional limitation 87% (p<0.01) and 66% (p<0.01) lower than that of low fit men, respectively, adjusting for age, body mass index at baseline and length of follow-up. The similar adjusted relative risk for high fit and moderate fit women was 73% (p<0.05) and 61% (p=0.05), respectively, lower than that for low fit women. The strong associations indicate that high physical fitness may be important in maintaining function in middle-aged and older men and women.
Phylogeographical Structure of Liquidambar formosana Hance Revealed by Chloroplast Phylogeography and Species Distribution Models

Field: Agricultural and Biological Sciences (Life Sciences)

To understand the origin and evolutionary history, and the geographical and historical causes for the formation of the current distribution pattern of Lquidambar formosana Hance, we investigated the phylogeography by using chloroplasts DNA (cpDNA) non-coding sequences and species distribution models (SDM). Four cpDNA intergenic spacer regions were amplified and sequenced for 251 individuals from 25 populations covering most of its geographical range in China. A total of 20 haplotypes were recovered. The species had a high level of chloroplast genetic variation (Ht = 0.909 ± 0.0192) and a significant phylogeographical structure (genetic differentiation takes into account distances among haplotypes (Nst) = 0.730 > population differentiation that does not consider distances among haplotypes (Gst) = 0.645; p < 0.05), whereas the genetic variation within populations (Hs = 0.323 ± 0.0553) was low. The variation of haplotype mainly occurred among populations (genetic differentiation coefficient (Fst) = 0.73012). The low genetic diversity within populations may be attributed to the restricted gene flow (Nm = 0.18). The time of the most recent common ancestor for clade V mostly distributed in Southwestern China, Central China, Qinling and Dabieshan mountains was 10.30 Ma (95% Highest posterior density (HPD): 9.74–15.28) dating back to the middle Miocene, which revealed the genetic structure of L. formosana was of ancient origin. These results indicated that dramatic changes since the Miocene may have driven the ancestors of L. formosana to retreat from the high latitudes of the Northern Hemisphere to subtropical China in which the establishment and initial intensification of the Asian monsoon provided conditions for their ecological requirements. This scenario was confirmed by the fossil record. SDM results indicated there were no contraction–expansion dynamics, and there was a stable range since the last interglacial period (LIG, 130 kya). Compared with the population expansion detected by Fu’s Fs value and the mismatch distribution, we speculated the expansion time may happen before the interglacial period. Evidence supporting L. formosana was the ancient origin and table range since the last interglacial period.
Outcome of cutaneous squamous cell carcinoma with microscopic residual disease after surgery and usefulness of postoperative radiotherapy: a retrospective cohort study

Field: Medicine (Health Sciences)

Abstract Background Microscopic residual disease (MRD) after surgery can be a challenging situation in cutaneous squamous cell carcinoma (CSCC) and there is a lack of evidence concerning its management. Objective To evaluate the prognosis of CSCC with MRD and the usefulness of postoperative radiotherapy (PORT) in CSCC with MRD. Methods Retrospective cohort study of CSCC with MRD through a 10‐year period (2010–2019) ( n = 244). Disease‐free survival and event‐free survival were assessed using R (v.3.4.1), considering competing risks. Evaluated outcomes were local recurrence (LR), nodal metastases (NMs), and disease‐specific death (DSD). Results Median age was 88y (IQR: 10.5). A total of 145 (59.43%) were men and 69 (28.28%) were immunosuppressed. Median tumour diameter and thickness were 19 and 6.4 mm (IQR 11 and 5.5 mm). Patients treated by re‐excision had a relapse rate of 4.3% compared with 11.30% and 29.71% in those who received PORT and observation ( P = 0.045). The use of PORT was associated with a lower risk of LR compared with observation (HR = 0.206 [0.049–0.859], P = 0.030), but not with a lower risk of NMs or DSDs. In the multivariable models, PORT was again associated with a lower risk of LR than observation (HR = 0.167 [0.039–0.708], P = 0.014), but not with lower risk of metastasis and death. Conclusions We always should try to obtain clear margins after surgery. PORT improves local control in CSCC with MRD, but when administered to the tumour bed, it does not reduce the risk of NM and DSD.
Activation of SIRT1 by Hyperbaric Oxygenation Promotes Recovery of Motor Dysfunction in Spinal Cord Injury Rats

Field: Neuroscience (Life Sciences)

Abstract Background: Emerging evidence demonstrated that hyperbaric oxygenation (HBO) therapy improved the locomotor dysfunction following spinal cord injury (SCI). Sirtuin1(SIRT1) has been characterized as neuroprotection in nerve system. However, whether SIRT1 is involved in alleviation of locomotor function by HBO therapy is unclear. Methods: The Basso, Beattie Bresnahan (BBB) locomotor rating scale was used to evaluate the open-field locomotor function. Western blot, real-time quantitative reverse transcription polymerase chain reaction, SIRT1 activity assay and enzyme-linked immunosorbent assays were performed to explore the molecular mechanisms in adult Sprague-Dawley rats. Results: We found that series HBO therapy significantly improved the locomotor dysfunction and ameliorated the decrease mRNA, protein and activity of spinal cord SIRT1 induced by traumatic SCI injury in rats. In addition, intraperitoneal injection SIRT1 antagonist EX-527 abolished the beneficial effects of series HBO treatment on locomotor deficits and SIRT1 activity loss caused by traumatic SCI injury. However, the rats undergone both series HBO therapy and SIRT1 agonist SRT1720 got the higher BBB score than that undergone series HBO treatment only. Importantly, series HBO treatment following the traumatic SCI injury inhibited the inflammatory cascade and apoptosis-related protein, which was retained by EX-527 and enhanced by SRT1720. Furthermore, EX-527 blocked the enhanced induction of autophagy series with HBO application. Conclusion: These findings demonstrated a new mechanism for series HBO therapy involving activation of SIRT1 and subsequent modulation of inflammatory cascade, apoptosis and autophagy, which contributed to the recovery of motor dysfunction. Key words: HBO, SIRT1, motor dysfunction, inflammation, autophagy, apoptosis
The High Pressure Diels-Alder Reactions of an Acylated Quinone Imine Ketal; A 3-Aminobenzyne Equivalent

Field: Chemistry (Physical Sciences)

The treatment of N-benzoyl-1-imino-p-benzoquinone-4-dimethyl ketal 1 with various dienes at 13 kbar leads to the formation of stable adducts. Treatment of these adducts with anhydrous acid leads to annulated amino benzenes and to amino naphthalenes.
Path separation of dissipation-corrected targeted molecular dynamics simulations of protein–ligand unbinding

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Protein–ligand (un)binding simulations are a recent focus of biased molecular dynamics simulations. Such binding and unbinding can occur via different pathways in and out of a binding site. Here, we present a theoretical framework on how to compute kinetics along separate paths and on how to combine the path-specific rates into global binding and unbinding rates for comparison with experimental results. Using dissipation-corrected targeted molecular dynamics in combination with temperature-boosted Langevin equation simulations [S. Wolf et al., Nat. Commun. 11, 2918 (2020)] applied to a two-dimensional model and the trypsin–benzamidine complex as test systems, we assess the robustness of the procedure and discuss the aspects of its practical applicability to predict multisecond kinetics of complex biomolecular systems.
Tertiary hyperparathyroidism with adenoma formation after renal transplantation.

Field: Medicine (Health Sciences)

Emphysematous gastritis is a rare and frequently fatal condition caused by invasion of gas-forming bacteria into the gastric wall. There have only been a handful of reported cases in the paediatric population, and none of these have evidence of candidal infection or mucormycosis. Patients typically present with abdominal pain, vomiting, malaena and haematemesis. Risk factors for emphysematous gastritis are those that interfere with the natural barriers to infection in the stomach. Diagnosis is made on the basis of typical appearances on abdominal CT. Treatment is generally conservative with surgery reserved for failed medical management or later complications. Antimicrobial cover should be broad with a low threshold for antifungals. It is important to look for predisposing factors for this condition, perhaps including an assessment of the patient9s immunocompetency. We present a 16-year-old boy with global developmental delay who presented with this condition associated with candidal infection.
Low power CMOS circuits

Field: Engineering (Physical Sciences)

Basic building block of CMOS integrated circuit like inverter, NAND, Latch and Full Adder will be simulated under low voltage condition using the Cadence software. This is an attempt to study the operations of these circuits when voltage is lowered to reduce the power consumption. Results will then be used to observe the impact of the voltage reduction on speed, data distortion and power consumption. Limit on the operating voltage at the testing frequency and the quality of the waveforms when the frequency is reduced can also be observed. Testing is also conducted for different design of Full Adders to understand how different design may also impact the performance at low operating voltage. This will also demonstrate how utilizing different design may also be a good method to reduce power consumption.
The effects of rehabilitation training on amyloid-beta peptide and insulin-degrading enzyme levels in the hippocampus of rats with vascular dementia

Field: Neuroscience (Life Sciences)

Objective To investigate the effects of rehabilitation training on hippocampal amyloid-beta peptide (Aβ) and insulin-degrading enzyme (IDE) levels in vascular dementia (VD).Methods Thirty female Sprague-Dawley rats were randomly assigned to a rehabilitation group (n =10),a model group (n =10) or a sham-operation group (n =10).An experimental VD model was established in the rats of the first 2 groups by bilateral common carotid artery permanent ligation.The rats in the rehabilitation group then received 1 h of rehabilitation training daily.Learning and memory were assessed at 4 weeks aftet the operation.Immunohistochemical staining was used to detect Aβ and IDE expression in the hippocampus dentate gyrus (DG) area.Results The rats in the rehabilitation group showed significantly better learning ability compared with the model group.The expression of Aβ in the rehabilitation group was significantly less than in the model group.The expression of IDE in the rehabilitation group was significantly greater Conclusion Rehabilitation can accelerate the recovery of learning and memory in VD,at least in rats The mechanism is possibly related to decreased accumulation of Aβ in the hippocampus due to up-regulation of the expression of IDE.

Key words:
Vascular dementia; Rehabilitation; Amyloid-beta peptide; Insulin-degrading enzyme