jimnoneill/paper-to-field-training huggingface dataset:
HIV-1 Down-Modulates γ Signaling Chain of FcγR in Human Macrophages: A Possible Mechanism for Inhibition of Phagocytosis

Field: Medicine (Health Sciences)

Abstract HIV-1 infection impairs a number of macrophage effector functions, thereby contributing to development of opportunistic infections and the pathogenesis of AIDS. FcγR-mediated phagocytosis by human monocyte-derived macrophages (MDM) is inhibited by HIV-1 infection in vitro, and the underlying mechanism was investigated in this study. Inhibition of phagocytosis directly correlated with the multiplicity of HIV-1 infection. Expression of surface FcγRs was unaffected by HIV-1 infection, suggesting that inhibition of phagocytosis occurred during or after receptor binding. HIV-1 infection of MDM markedly inhibited tyrosine phosphorylation of the cellular proteins, which occurs following engagement of FcγRs, suggesting a defect downstream of initial receptor activation. FcγR-mediated phagocytosis in HIV-infected MDM was associated with inhibition of phosphorylation of tyrosine kinases from two different families, Hck and Syk, defective formation of Syk complexes with other tyrosine-phosphorylated proteins, and inhibition of paxillin activation. Down-modulation of protein expression but not mRNA of the γ signaling subunit of FcγR (a docking site for Syk) was observed in HIV-infected MDM. Infection of MDM with a construct of HIV-1 in which nef was replaced with the gene for the γ signaling subunit augmented FcγR-mediated phagocytosis, suggesting that down-modulation of γ-chain protein expression in HIV-infected MDM caused the defective FcγR-mediated signaling and impairment of phagocytosis. This study is the first to demonstrate a specific alteration in phagocytosis signal transduction pathway, which provides a mechanism for the observed impaired FcγR-mediated phagocytosis in HIV-infected macrophages and contributes to the understanding of how HIV-1 impairs cell-mediated immunity leading to HIV-1 disease progression.
Fabrication of Fuel Cells with High Power Density Using Micro Electrical Discharge Machining Milling

Field: Engineering (Physical Sciences)

Light and thin bipolar plates are essential in increasing the power density of a fuel cell. To construct high-aspect-ratio micro flow channels in such plates is, however, a big challenge. This study reports on machining micro flow channels in metallic bipolar plates using micro electrical discharge machining milling (micro EDMM) with a tungsten carbide electrode. We successfully machined metallic bipolar plates with 500μm channel and rib widths, height of 600μm in a reaction area of 20mm × 20mm, on 1mm thick of SUS316L stainless steel. The optimal operating parameters were explored and discussed. The performance of resulting fuel cell (Metallic-FC) was compared with a commercial available fuel cell composed of graphite bipolar plates (Graphite-FC). The high temperature of Metallic-FC increases its electrochemical reaction rate and consequently yields higher power density (723 mWcm -2 ) then that of Graphite-FC (687.3 mWcm -2 )
The laminar space in the diagnosis of rotational flexion injuries of the cervical spine

Field: Medicine (Health Sciences)

We measured the distance between the spinolaminar line and the articular pillars of the cervical spine (the laminar space), identified on lateral radiograph, to determine the diagnostic value of changes in this measurement in cases of unilateral facet dislocation. Twenty-seven cases of unilateral facet dislocation were compared with 70 normal spines and with 29 cases of hyperflexion injuries without unilateral facet dislocation. Abrupt alteration of the laminar space between two adjacent levels was found to be an accurate measure of rotation of the spine at the levels concerned; on the basis of this alteration, we were able to correctly diagnose 23 of 27 cases of unilateral facet dislocation and 22 of 23 cases of unilateral facet dislocation between C2 and C6. In only two of the 70 normal cases was a similar alteration of the laminar space seen, and one of these was due to a previous fracture. In none of the 29 cases of hyperflexion injury without unilateral facet dislocation was there abrupt alteration of the laminar space. We conclude that abrupt alteration of the laminar space is an accurate determinant for rotational anomalies of the cervical spine and, in particular, for unilateral facet dislocation.
User-centric networking and services: part 2 [Guest Editorial]

Field: Computer Science (Physical Sciences)

Iser-centric networks (UCNs) can be seen as a recent architectural trend of self-organizing autonomic networks where the Internet end user cooperates by sharing network services and resources. UCNs are characterized by spontaneous and grassroots deployments of wireless architectures, where users on such environments roam frequently and are also owners of networking equipment. Common to UCNs is a social behavior that heavily impacts network operation from an end-to-end perspective.
CHARACTERISTICS OF DISCONTINUOUS STARCH GEL ELECTROPHORESIS APPLIED TO MYOGEN FROM CHICKEN BREAST MUSCLE

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The essential characteristics of discontinuous starch gel electrophoresis, introduced by Poulik (1), were studied by varying the compositions of gel and bridge buffers, by conductivity measurements within the gel during electrophoresis, and by examination of electropherograms of chicken breast myogen, a protein mixture prone to influence by the buffer medium. The obligatory ingredients of discontinuous buffer systems were Tris cation in the gel medium, and borate anion in the bridge solution. The cation of the bridge solution was immaterial, and any anion other than borate was adequate in the gel. A flux of borate, migrating through the gel across a matrix of Tris adsorbed to starch, profoundly reduced conductivity and displaced protein-ion complexes from the support phase in an electrochromatographic manner. Some new discontinuous systems are introduced, but despite the striking patterns obtained these conditions are not necessarily the most informative for starch gel electrophoresis of cationic proteins, including major components of myogen.
A Study on Whether Spending Misdirected Bitcoins Constitutes Embezzlement

Field: Arts and Humanities (Social Sciences)

블록체인 기반 암호화폐인 비트코인이 시중에 유통되고 현금이나 수표, 신용카드를 대신하는 지급결제수단으로 활용되면서 형법학은 새로운 과제를 맞닥뜨리고 있다. 암호화폐를 수단으로 한 범죄, 직접 객체로 한 범죄가 발생하면서 그 법적 성격에 대한 규명과 적절한 법적 규율이 기존 형법의 한계를 뛰어넘고 있기 때문이다.BR 그런데 최근 대법원은 2020도9789 판결에서 알 수 없는 경위로 거래소의 가상지갑에 들어 있던 비트코인이 자신의 계정으로 이체되자 이 비트코인을 반환하지 않고 자신의 다른 계정에 이체하여 피해자에게 동액 상당의 손해를 가한 사건에서 배임죄를 인정하지 않았다.BR 이번 2020도9789 대법원 판결은 가상자산이 배임죄에서의 ‘재산상의 이익’에 해당하는지 여부, 나아가 형법을 적용하면서 가상자산에 대해 법정화폐와 동일하게 보호해야 하는지 여부, 원인불명으로 비트코인을 착오 이체받은 자가 이를 사용 · 처분한 경우, 신의칙을 이유로 배임죄로 처벌할 수 있는지 여부에 대해 중요한 판단을 하였다.BR 본 논문은 우선 비트코인의 법적 성격을 금융거래정보의 보고 및 이용 등에 관한 법률의 개정을 고려하여 재산상의 이익으로서 가상자산이라고 평가한 후, 종래 신의칙을 근거로 착오송금에 대해 횡령죄를 인정해 온 판례에 비춰 이번 대법원의 판결이 정당한 것인지, 논리적 · 이론적 정합성을 갖추고 있는지 평가해보고 처벌의 공백지대는 없는 것인지 살펴보았다.BR 그 결과 배임죄의 해석에서 타인의 사무처리자성을 엄격히 판단하는 대법원의 경향에 동의하더라도 착오이체된 비트코인의 임의처분행위가 법정화폐와의 차이, 부당이득반환청구 주체의 불분명성, 거래의 위험성 등으로 인해 배임죄를 구성하지 않는다고 하는 것은 착오송금에 대해 횡령죄를 인정하는 것과의 균형상 타당하지 않음을 논증하였으며, 처벌의 공백지대를 해소할 수 있는 입법적 방안으로 제360조의2로 가칭 ‘이체자산 횡령죄’를 신설하는 방안이 있음을 모색하였다.
Viscoplastic strain modeling of asphalt binder based on repeated creep recovery test

Field: Engineering (Physical Sciences)

The viscoelastic and viscoplastic properties of asphalt binder are valuable to the performance research on the asphalt mixture and pavements. Especially at high-temperature condition, the viscoplastic characteristics of binder play an important role in rutting-resistant performance. This paper presents a viscoplastic modeling method, which originates from the strain-hardening model, to study the unrecoverable strain response for binder in a repeated shear creep recovery test using a Dynamic Shear Rheometer (DSR). Two types of asphalt binders were evaluated in this study, namely the neat binder PG58-28 and the SBS polymer-modified binder PG70-28. In order to fit the model coefficients, a series of 10 cycles repeated creep recovery test were designed to conduct under multiple stress levels 25 Pa, 50 Pa, 100 Pa, doubled to 6400 Pa and three different time durations which included 0.1 s creep + 0.9 s recovery and 1 s + 9 s as well as 10 s + 90 s. Test results and modeling work indicate that, compared with the measured viscoplastic strain, the strain-hardening viscoplastic model can work well on the binder unrecoverable strain response prediction in repeated creep recovery test under lower stress levels and shorter creep duration and it is necessary to take the damage factor into consideration in the future work.
Inter –Linkages Between Climate Change Vulnerability and Inequality an Empirical StudyAcross Hill, Foothill, Drought and Coastal Regions of West Bengal, India

Field: Social Sciences (Social Sciences)

India is one of the vulnerable countries in the world in terms of climate events. The poor people and poor regions are badly affected by climate change. On the other hand, the reduction of vulnerability received a top priority in the Sustainable Development Goals of the United Nations. The present paper attempts to examine the inter-linkages between climate change vulnerability and inequality empirically across four agro-climatic regions of West Bengal like hill, foothill, drought and coastal regions. Vulnerability in the present paper is measured by adopting composite livelihood vulnerability index and income (consumption) inequality is measured by Gini coefficient. This is an empirical paper based on primary data collected from 627 households over 15 villages in different agro-climatic regions of West Bengal during 2018- 2019. The result of the paper showed that there is a positive correlation relation between income inequality (consumption) and vulnerability. The higher inequality is accompanied by higher vulnerability and vice versa. The study draws an important policy implication for reduction of vulnerability as well as reduction of inequality. The poverty reduction measures are not sufficient to reduce inequality i.e., if inequalities are on the rise the anti-poverty measures cannot reduce such inequality.
EFFECT OF SAVORY EXTRACT SUPPLEMENTATION ON SOME PRODUCTIVE TRAITS AND ECONOMIC EFFICIENCY OF COMMON CARP (Cyprinus carpio L.)

Field: Agricultural and Biological Sciences (Life Sciences)

The purpose of this study is to evaluate the effectof a dietary savory extract supplement on the survival rate, growthperformance, feed conversion ratio and economic efficiency of common carp (Cyprinus carpio L.) reared in arecirculation system. Thirty-two carps were allotted into two experimentalvariants, each of them comprising two replications with 8 fish in a group. Theaverage initial live weight of fish from both replications from the controlgroup (CG) and experimental group (EG) was 866.56±113.99 g and 866.81±119.10 g,respectively (p&amp;gt;0.05). They were kept in concrete tanks with efficient watervolume of 0.8 m3, elements of the recirculation system. Carps werefed pelleted carp feed with 25% crude protein, produced with pellet size of 6mm. The feed of fish from the EG was supplemented with 1% powdered savoryextract, after lubricating the pellets with 5 ml sunflower oil per 100 g feed.Control carp received the same amount of sunflower oil-lubricated feed. Thedaily ration of fish from both replications was 1.8% of their live weight. Theexperiment duration was 45 days. Survival rates during the experiment showed 100% survival in carps, supplemented with 1% savory extractas well as in control fish. The average individual weight gain of carps from the two EG replications (supplemented with1% savory extract) was154.63±28.39 g, which was higher than that of controls by 57.18% (Table 3), as thedifferences were statistically significant (p&amp;lt;0.001). At the end of the trial, theanalysis of consumed feed amount showed that feed conversion ratio in the groupsupplemented with 1% savory extract was 2.25±0.43 e.g. by 67.11% lower thanthat of control group, as the differences were statistically significant(p&amp;lt;0.001). The group that received 1% savory extract exhibited bettereconomic conversion ratio (1.98), by 42.42% lower than that of thenon-supplemented group.
A comparison of deep machine learning algorithms in COVID-19 disease\n diagnosis

Field: Computer Science (Physical Sciences)

The aim of the work is to use deep neural network models for solving the\nproblem of image recognition. These days, every human being is threatened by a\nharmful coronavirus disease, also called COVID-19 disease. The spread of\ncoronavirus affects the economy of many countries in the world. To find\nCOVID-19 patients early is very essential to avoid the spread and harm to\nsociety. Pathological tests and Chromatography(CT) scans are helpful for the\ndiagnosis of COVID-19. However, these tests are having drawbacks such as a\nlarge number of false positives, and cost of these tests are so expensive.\nHence, it requires finding an easy, accurate, and less expensive way for the\ndetection of the harmful COVID-19 disease. Chest-x-ray can be useful for the\ndetection of this disease. Therefore, in this work chest, x-ray images are used\nfor the diagnosis of suspected COVID-19 patients using modern machine learning\ntechniques. The analysis of the results is carried out and conclusions are made\nabout the effectiveness of deep machine learning algorithms in image\nrecognition problems.\n
INTELLIGENT CANE ROBOT FOR WALKING ASSISTANCE OF ELDER AND HANDICAPPED PEOPLE

Field: Engineering (Physical Sciences)

The main aim of the project is to design An intelligent cane for aiding elderly and handicapped people's walking. Our system is designed by using ARM 32- bit micro controller which supports features for the development of cane robot. Our robot is used as a support for elders and for handicapped people. Our system contains ultrasonic sensors and IR sensor and motors for controlling movement. We use three ultrasonic sensors placed at three directions of robot which detects leg movement of person then based on that leg movement robot direction gets changes. If a person tries to move straight the ultrasonic sensor detects his leg movement then simultaneously cane robot also moves one foot forward. If ultrasonic sensor connected at sides detects leg movement then it changes one foot either left or right direction. The IR sensor is connected to robot at front which is used to detect obstacles in front. When it detects obstacles in front of it then it automatically stops movement of robot. Motors connected to controller are used for robot movement. For holding stick by person we use cane through this movement is controlled.
Preseason strength and flexibility imbalances associated with athletic injuries in female collegiate athletes

Field: Medicine (Health Sciences)

One hundred thirty-eight female collegiate athletes, par ticipating in eight weightbearing varsity sports, were administered preseason strength and flexibility tests and followed for injuries during their sports seasons. Strength was measured as the maximal isokinetic torque of the right and left knee flexors and knee extensors at 30 and 180 deg/sec. Flexibility was meas ured as the active range of motion of several lower body joints. An athletic trainer evaluated and recorded injuries occurring to the athletes in practice or compe tition. Forty percent of the women suffered one or more injuries. Athletes experienced more lower extremity injuries if they had: 1) a right knee flexor 15% stronger than the left knee flexor at 180 deg/sec; 2) a right hip extensor 15% more flexible than the left hip extensor; 3) a knee flexor/knee extensor ratio of less than 0.75 at 180 deg/sec. There was a trend for higher injury rates to be associated with knee flexor or hip extensor imbalances of 15% or more on either side of the body. These data demonstrate that specific strength and flexibility imbalances are associated with lower extrem ity injuries in female collegiate athletes.
Breeding of "Jinyou 752"——a High Yield and Quality Mid-late Hybrid Rice Variety

Field: Agricultural and Biological Sciences (Life Sciences)

A new mid-late hybrid rice combination Jinyou 752 was bred from Jin A/752(752 is a strong restoring line bred by Rice Research Institute ,Jiangxi Academy of Agricultural Sciences). The combination has big panicle, many grains per panicle, high setting rate, quality rice and high yield in common and seed production, strong resistance to diseases, ideal plant type and so on. In addition, the techniques of high-yielding culture and seed production of Jinyou 752 were introduced in the paper.
Gentamicin Penetrates the Intracellular Compartment in Neonatal Rats

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Conference Abstract| September 01 1978 Gentamicin Penetrates the Intracellular Compartment in Neonatal Rats R. D. G. Milner; R. D. G. Milner 1Department of Paediatrics, University of Sheffield Children's Hospital, Sheffield Search for other works by this author on: This Site PubMed Google Scholar G. R. Milner; G. R. Milner 1Department of Paediatrics, University of Sheffield Children's Hospital, Sheffield Search for other works by this author on: This Site PubMed Google Scholar D. Lancaster D. Lancaster 1Department of Paediatrics, University of Sheffield Children's Hospital, Sheffield Search for other works by this author on: This Site PubMed Google Scholar Author and article information Publisher: Portland Press Ltd © 1978 The Biochemical Society and the Medical Research Society1978 Clin Sci Mol Med (1978) 55 (3): 26P–27P. https://doi.org/10.1042/cs055026Pc Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation R. D. G. Milner, G. R. Milner, D. Lancaster; Gentamicin Penetrates the Intracellular Compartment in Neonatal Rats. Clin Sci Mol Med 1 September 1978; 55 (3): 26P–27P. doi: https://doi.org/10.1042/cs055026Pc Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsClinical Science Search Advanced Search This content is only available as a PDF. © 1978 The Biochemical Society and the Medical Research Society1978 Article PDF first page preview Close Modal You do not currently have access to this content.
Cytochemical Studies on the Neurosecretory Cells and Neurohypophysis of the Common Garden Lizard, <i>Calotes versicolor</i> (Daudin)

Field: Neuroscience (Life Sciences)

1. Using specific stain techniques, almost negative reaction for glycogen and positive reactions for acid and alkaline phosphatases, PAS-reactive substances, basophilic substances, cystine, arginine, mucoprotein, bound lipids and zinc are observed in the hypothalamo-neurohypophysial system of the lizard Calotes versicolor.2. The PAS-reactive substances are probably mucoprotein-lipoprotein complex.3. The significance of the positive reaction for arginine and zinc in the neurosecretory system is discussed in the light of current finding on their relationships with the neurosecretory substances.
Adult Arnold-Chiari malformation: a postpartum case presentation

Field: Medicine (Health Sciences)

Abstract Adult Arnold-Chiari malformation, also known as Chiari malformation type I, typically occurs in women during early adulthood and can be a cause of unexplained headaches, as well as associated syringomyelocele. In this unique case report, a 32-yearold, postpartum woman with posturally induced headache from Chiari malformation type I had symptoms occur for the first time during pregnancy. Magnetic resonance imaging of the brain confirmed the diagnosis and is the neuroimaging study of choice in such cases. Neurosurgical decompression, when performed early, is highly successful in symptomatic individuals.
Light-Stimulated Micromotor Swarms in an Electric Field with Versatile Spatial, Temporal, and Mode Control

Field: Computer Science (Physical Sciences)

Abstract Swarming, a phenomenon widely present in nature, is a hallmark of non-equilibrium living systems that harness external energy into collective locomotion. The constituting units with sizes ranging from nanometers to meters form complex patterns and synchronous motion. The creation and study of swarms made of artificial active matter may provide insights to their biological counterparts and shed light to the rules of life. Here, we propose an innovative concept and associated actuation mechanism for rationally creating multi-modal swarms with unprecedented spatial, temporal, and mode control. The research is realized in a system made of optoelectric semiconductor nanorods that can rapidly morph into three distinct modes, i.e., network formation, collectively enhanced rotation, and droplet-like clustering, and switch in between with light stimulation in an electric field. Theoretical analysis and semi-quantitative modeling well explain the observation via understanding the competition between two countering effects: the electrostatic assembly for orderliness and electrospinning-induced disassembly for disorderliness. This work could inspire the rational creation of a new class of reconfigurable swarms for both fundamental research and emerging applications.
The Other Side of Precariousness: The Cost of Job Loss

Field: Social Sciences (Social Sciences)

The increasing precariousness of work, its concentration among vulnerable groups, and the divide between secure, primary sector workers and the expendable army of casual and contract labour is well documented. Much less attention has been directed to the other side of precariousness – the practices that increase the costs of job loss for workers in the primary labour market. In an era of low official unemployment and labour shortages, where the discourses of neo-liberal flexibility dominate, it is easy to assume that job loss is now a costless and effortless transition and that ‘labour adjustment’ is no longer a policy issue. As a result, workers’ hard-won rights to compensation for the job losses that result from corporate failure are being eroded or abolished. By exploring the interrelations between the personal, financial and career-related impacts of job loss for former Ansett airlines employees, this \npaper shows that job loss remains an extremely costly life-changing event. The conclusion argues that the costs of job loss cast a shadow over the rhetoric of flexibility and that public awareness of these costs underpin the contemporary disciplining of the apparently secure, primary sector workforce.