jimnoneill/paper-to-field-training huggingface dataset:
Uji Efektivitas Antihiperglikemia Ekstrak Daun Puring (Codiaeum variegatum) Terhadap Mencit Jantan (Mus musculus L.)

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Diabetes mellitus (DM) is a metabolic disease due to insulin secretion disorders due to pancreatic cell damage. Puring plants (Codiaeum variegatum) in Indonesia are more identical as cemetery plants and garden decorations. The purpose of this study was to see the antihyperglycemic effect of croton leaf extract. This study was conducted by making croton leaf extract, phytochemical screening, and antihyperglycemia testing by observing the decrease in blood glucose levels in mice induced by alloxan. Based on the results of phytochemical tests, croton leaves contain compounds such as flavonoids, terpenoids, phenolics, saponins, and alkaloids. The flavonoid content found in plants has a role as an antihyperglycemic compound and antioxidant. The results of the study were analyzed by One Way ANOVA for the percentage parameter of blood glucose reduction and continued with the Tukey post hoc test. The results of observations showed that the administration of croton leaf extract in reducing blood glucose levels at a dose of 300 mg/kgBW, and showed no significant difference with the positive control group. The conclusion of this study is that a dose of 300 mg/kgBW of croton leaf extract is the best dose in reducing blood glucose levels in mice.
Alchemilla parcipila Juz. and A. stellaris Juz. as polemochores in Finland – the first records outside Russia – and the correct identity of A. polemochora S.E.Fröhner

Field: Agricultural and Biological Sciences (Life Sciences)

Two species of the genus Alchemilla are reported from the province of Kainuu in eastern central Finland as new to the country. A. parcipila was collected in 2017 in the municipality of Kuhmo at the sites of two wartime Russian military camps. Review of older herbarium material (H, OULU) revealed several previous collections of the species from these two localities between 1957 and 2016. The species is native to western Siberia and the easternmost parts of European Russia in the Ural Mountains. From this original area, it was probably already introduced into parts of central and northwestern Russia in ancient times by Russian traders and settlers. A. stellaris was also collected in 2017 at the site of a Russian wartime camp in the municipality of Suomussalmi. This is the only known locality of the species in Finland. A. stellaris is endemic to the subboreal and southern boreal zone of European Russia, from Tver in the west to Perm and Ekaterinburg in the east. Outside its native range, the species is known as a neophyte in northwestern Russia from Chibiny, Kola Peninsula and Petrozavodsk, Republic of Karelia. Both species were found for the first time outside of Russia. Another Russian polemochore, A. polemochora, was described in 1981 from two localities in Finland, which have so far remained the only known finds of the species. A. polemochora is here synonymized with A. sergii, described from the province of Moscow, central Russia, in 1972.
Study of the Baseline Finite Element Model of a Cable-Stayed Bridge Based on the Field Inspection Data

Field: Engineering (Physical Sciences)

For steel cable-stayed bridges which have been operating for many years, their static and dynamic parameters have been being changed because of corrosion and overloading. Therefore, an adjustable numerical model, describing and orienting all the various phases of the safety status of bridges, is needed for a theoretical guide of daily maintenance or periodical repair for them. In order to build such a model reflecting the different phases of working conditions of a bridge, a link between the model and the present condition of the targeted bridge should be erected by periodical field inspections for the structure. In this paper, backed on a practical engineering example, the Shengli cable-stayed bridge of Dongying, a finite element model (FEM) based on the periodical field inspection data was proposed, which could possess a strategy modified correspondingly according to parts or all of the results in the field inspections. Specifically, for the initial FEM, three important issues in the modeling of such a complicated bridge, such as simulation of boundary conditions, equivalence of orthotropic steel deck, and implementation of accurate cable tensions, were firstly studied. Then, the initial finite element model built was modified in terms of the optimization principle by minimizing the difference between the static deflections resulting from the field inspection and those calculated by the FEM before being modified. Lastly, dynamic results from the field inspection were compared with those from the optimized FEM to justify feasibility and reasonability of the developed three-dimension FEM which could reflect one or some certain properties of the structure we were emphatically paying attention to. This model-building and model-modifying method for the baseline FEM of the Shengli cable-stayed bridge also provided reference for the similar existing cable-stayed bridges.
Ultrasonographic Assessment with Three-Dimensional Mode of the Urethral Compression Effect following Sling Surgery with and without Mesh Surgery

Field: Medicine (Health Sciences)

Background. The aim of this study was to assess anatomical changes in the urethra at rest and during straining following sling surgery with and without transvaginal mesh surgery (TVM) in women with stress urinary incontinence (SUI) with or without pelvic organ prolapse (POP) using three-dimensional ultrasonography. Methods. 76 women with SUI with or without pelvic organ prolapse after sling surgery. They underwent sling surgery alone (S group, n=36) or concomitant TVM (M group, n=40). All patients underwent urinalysis, pelvic examinations, urodynamic study, 3D perineal ultrasonography, and personal interviews before and 1 year after surgery. The urethral area was calculated from the axial plane of perineal ultrasonography by multiplying π by the long and short axes of the urethral lumen. Results. The axial area of the middle and distal urethra during straining was significantly smaller than at rest in both groups (P<0.001). In addition, the length of the short axis of the proximal urethra was significantly shorter in those undergoing sling surgery alone during straining compared with those undergoing concomitant sling and mesh surgery (P<0.001). Conclusions. There was a greater impact on the proximal urethra in women who underwent sling surgery alone than those who underwent sling and TVM surgery together.
Scavenging of Anesthetic Gases

Field: Computer Science (Physical Sciences)

We propose a language that allows agents to distribute data with usage policies in a decentralized architecture. In our framework, the compliance with usage policies is not enforced. However, agents may be audited by an authority at an arbitrary moment in time. We design a logic that allows audited agents to prove their actions, and to prove their authorization to posses particular data. Accountability is defined in several flavors, including agent accountability and data accountability. Finally, we show the soundness of the logic.
Relationship Between Knowledge And Perceptions Of Geodiversity, Biodiversity, And Cultural Diversity With The Formation Of Students' Environmental Care Attitudes To The Existence Of The Ciletuh Pelabuhanratu Geopark Area

Field: Social Sciences (Social Sciences)

This research aims to determine the relationship between knowledge and perceptions of geodiversity, biodiversity, and cultural diversity on environmental care attitudes. There is a legal protection that underlies all parties to know and participate in maintaining the preservation of geopark, includi
Coordination chemistry of imidazole derivatives. A search for carbon-bound chelates with first-row transition metal ions

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCoordination chemistry of imidazole derivatives. A search for carbon-bound chelates with first-row transition metal ionsRichard J. Sundberg, Ibrahim. Yilmaz, and Donald C. MenteCite this: Inorg. Chem. 1977, 16, 6, 1470–1476Publication Date (Print):June 1, 1977Publication History Published online1 May 2002Published inissue 1 June 1977https://pubs.acs.org/doi/10.1021/ic50172a047https://doi.org/10.1021/ic50172a047research-articleACS PublicationsRequest reuse permissionsArticle Views273Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
1189 Cervical glandular intra-epithelial neoplasia – 8 years of a tertiary centre experience

Field: Medicine (Health Sciences)

Introduction/Background

Cervical glandular intraepithelial neoplasia (CGIN) is a premalignant lesion of the uterine cervix. Excision of CGIN is the goal of treatment, often requiring a large loop excision of the transformation zone (LLETZ) and close follow-up due to high risk of recurrence and residual disease. This study aims to review the management of CGIN in a tertiary center.

Methodology

We selected all cytology-based glandular disease referrals to our center, between 2015 and 2022. Patients underwent a colposcopy assessment followed by excisional treatment of glandular disease and follow-up according to the United Kingdom guidelines. Data was collected on patient's age, smoking status, parity, colposcopy impression, diagnostic biopsy vs LLETZ, number and types of treatment, LLETZ depth and margins, and recurrence status. We used Microsoft Excel for statistic analysis.

Results

Our sample consists of 33 patients with a mean age of 35 years(±7.7), of which 14 (42%) are nulliparous and 5 (15%) smoke. All patients underwent a colposcopic examination and epithelial changes were documented in 24 (73%) cases. A biopsy was taken in 23 (70%) patients, but only 9 (39%) showed glandular disease. The remaining 10 (30%) patients had a diagnostic LLETZ, with a 10/10 (100%) detection rate for glandular disease. Apart from one case, all 32 (97%) patients had a LLETZ. Mean depth of excision was 12.7mm(±4.1). Endocervical, ectocervical and radial margins were positive in 15 (47%), 9 (28%) and 7 (22%) cases respectively, therefore 15 (47%) patients required an additional procedure – repeat LLETZ, trachelectomy or hysterectomy. Overall, 26 (81%) histopathology results confirmed CGIN, 2 (6%) adenocarcinoma in situ and 2 (6%) cervical adenocarcinoma. To date, 28 patients (87%) remain free of disease, while 4 (13%) lost follow-up.

Conclusion

In our study, 47% patients required two or more excisional procedures to treat glandular disease. To date, 87% of patients remain free of disease.

Disclosures

None
Can Marshall plus Malthus Explain the Evolution of Ancient Societies? A Review ofEconomic Prehistoryby Dow and Reed

Field: Economics, Econometrics and Finance (Social Sciences)

In a work of extraordinary scope and scholarship, Gregory K. Dow and Clyde G. Reed deploy conventional microeconomic theory to explain “six transitions that shaped the world,” namely, the transitions to sedentism, farming, inequality, war, cities, and states. The models they offer provide a level of clarity about potential causal mechanisms that is unusual in the archaeological literature. But we are not convinced by some of their key empirical claims in light of current archaeological evidence, and we think that contemporary economics—including evolutionary game theory—has more appropriate models to offer than the Marshallian approach taken by the authors. (JEL C73, N10, N40, N50, Q10, Q54)
The Decrease in Brain Glycogen during Prolonged Exhaustive Exercise Is Coupled with Hypoglycemia

Field: Neuroscience (Life Sciences)

Blood glucose is the primary fuel for the brain. However, evidence has recently been presented that the glucose storage molecule, glycogen, is also an important energy source in the brain when the glucose supply from blood is inadequate (during hypoglycemia). On the other hand, we previously reported that neuronal metabolic activity increases during exercise, and prolonged exhaustive exercise induces glycogen depletion in some brain loci (cortex, hippocampus, hypothalamus, cerebellum, and medulla oblongata). However, it is uncertain whether decreased brain glycogen during exhaustive exercise is due to hypoglycemia. PURPOSE: We therefore examined the effects of various durations of running exercise on blood glucose and brain glycogen levels in rats, to clarify their relation during exercise. METHODS: Rats were exercised using a treadmill running at 20 m/min for 30, 60, and 120 min. Brain was fixed immediately after the running by the high-energy focused microwave irradiation (MI), which can momentarily inactivate glycogenolysis enzymes. Following MI, the five brain loci, two skeletal muscles (soleus and plantaris), and the liver were collected and were used to determine glycogen levels. We also collected blood immediately after exercise to determine blood glucose levels. RESULTS: At the end of 30 and 60 min of running, blood glucose levels did not decrease compared with those at rest. However, at the end of 120 min of running, blood glucose was 46% lower than at the resting level (p < 0.05). Similar to blood glucose levels, after 30 and 60 min of running, glycogen levels in the five brain loci were not significantly different from those at rest, but decreased after 120 min of exercise (p < 0.05). However, Glycogen levels in skeletal muscles and the liver were significantly decreased after 30 min of running, and decreased further after 60 min and 120 min of running. Thus, the decrease in brain glycogen levels was highly correlated with the decrease in blood glucose levels (r > 0.7). CONCLUSION: Prolonged exhaustive exercise resulted in a decrease in brain glycogen, which was closely related to a similar decrease in blood glucose levels, suggesting the possibility that brain glycogen reduction elicited by exercise is due to hypoglycemia. This may provide a clue towards understanding the mechanisms related central fatigue.
RP - HPLC Determination of Simvastatin in Human Plasma by Solid - Phase Extraction

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective: To establish an analytical method of simvastatin in human plasma. Method: The simvastatin in plasma was processed by Waters OASIS solid - phase extractor, the column was Waters Symmetry C18 (250 mm ×4.6 mm, 5μm). Lovastatin was used as internal standard. The mobile phase was 0.1% phosphate solution (pH 4.0) -acetonitrile (40:60) , the detective wavelength was 238 run, flow rate was 1.2 mL·min-1. Results: The range of calibration curve was 1.0-35.0 ng·mL-1 (r = 0.9977). The lowest detectable concentration was 0.8 ng·mL-1. The added recovery of low, medium and high concentration were within 97.3% - 108.0% , and the RSD of intra- day and inter- day assay were within 5.9% - 8.8% . Conclusion: The method is rapid, sensitive and efficient.
PENGARUH STRATEGI COPING TERHADAP TINGKAT STRES PADA CAREGIVER INFORMAL YANG MERAWAT PENDERITA SKIZOFRENIA DI POLI RAWAT JALAN RUMAH SAKIT JIWA DR. SOEHARTO HEERDJAN JAKARTA BARAT

Field: Psychology (Social Sciences)

Limited psychiatric healthcare and being chronic, schizophrenia makes schizophrenia patient’s family hold important role as informal caregivers. Objective of this research was to know demography characteristic distribution and impact of coping strategy against schizophrenia informal caregiver’s stress level at Dr. Soeharto Heerdjan psychiatric hospital, out-patient unit. Coping stress vary depends on individual characteristics. This research was set to observational analytic with cross sectional design. Subjects of research were 32 caregivers, adapting research instrument CSI-SF 32 items and PSS-14 items. The result of research, majority of the caregivers is a woman and middle adulthood age. Most of caregivers goes to work and tend more than 4 years with nursing time more than 6 hours /day. There was impact of coping strategy against stress level of schizophrenia informal caregivers (p = 0,006). Most used coping strategy was adaptive coping with medium stress level. Long term could increase caregivers burden, so that it can trigger stress and could lower caregivers mental health status and could affect the treatment quality for schizophrenia patient. Writer recommended psychiatric healthcare to put psychological awareness and psycho-education intervention of stress management for caregivers.
Owning Up to Negative Ingroup Traits: How Personal Autonomy Promotes the Integration of Group Identity

Field: Psychology (Social Sciences)

Abstract Objective Our experiences, attributes, and behaviors are diverse, inconsistent, and often negative. Consequently, our capacity to assimilate divergent experiences—particularly negative aspects—is important to the development of a unified self. Whereas this process of integration has received attention at the level of personal identity, it has not been assessed at the level of group identity. Objective We examined the mechanisms involved in integrating positive and negative ingroup identities, as well as related outcomes. Method In three experiments, participants ( N = 332) high and low in autonomy identified either positive or negative aspects of their ingroup and then indicated the extent to which they integrated the attribute. Results Those high in personal autonomy integrated both positive and negative identities, whereas those low in autonomy acknowledged only positive identities. Study 2 showed that, regardless of identity valence, those high in autonomy felt satisfied and close with their group. Conversely, those low in autonomy felt less close and more dissatisfied with their group after reflecting on negative identities. Finally, reflecting on a negative identity reduced prejudice, but only for those high in autonomy. Conclusions Owning up to negative group traits is facilitated by autonomy and demonstrates benefits for ingroup and intergroup processes.
The lasting impact of parental migration on children’s behavioral outcomes: evidence from China

Field: Social Sciences (Social Sciences)

For much of the past three decades, China has witnessed a dramatic and steady increase in internal migration and thus has a huge population of left-behind children. The impact of childhood left-behind experiences has been carefully studied, but research on the long-term effects of these experiences is generally lacking. Capitalizing on a study of migrant workers conducted in Yangtze River Delta and Pearl River Delta regions, we extend this line of research by examining how childhood experiences of being left behind by migrant parents affect the behaviors of adults. Our study shows that people with left-behind experiences (1) are more likely to work overtime, which could result from avoidance of close interpersonal interaction after work; (2) spend a larger part of their income on surfing the Internet, indicating that they prefer activities not involving direct contact with other people; and (3) occurring at different stages of life can have varied long-term impacts. This study not only echoes earlier studies on the relationship between family structure and children's behavioral outcomes, but also provides substantial evidence of the long-term negative effect of childhood left-behind experiences on adults.
Interaction of β Radiation and 2-Anthramine for Induction of Skin Tumors in Rats

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

When ..beta.. radiation of a small area of skin on the back of rats was followed by repeated applications of 2-anthramine to the same area, the two treatments appeared to act synergistically as carcinogenic stimuli for induction of skin tumors.
OUT OF PLANE FLEXURAL BEHAVIOUR OF THIN POLYSILICON FILMS: MECHANICAL CHARACTERIZATION AND APPLICATION OF THE WEIBULL APPROACH

Field: Engineering (Physical Sciences)

A new MEMS for on-chip mechanical testing of 0.7 µm thick polysilicon film has been designed, modelled and fabricated. The polysilicon film is electrostatically loaded under bending until rupture in the out of plane direction, by means of electrostatic attraction in the direction orthogonal to the substrate. This is at difference with previous works of the same Authors, in which results relevant to in plane loading conditions have been presented. 3D Finite Element (FE) and Boundary Element (BE) models of the structure were used during the design and data reduction phases. Tests were carried out at room temperature and at atmospheric humidity. The measured Young’s modulus obtained on 20 tested polysilicon specimens was 174 ± 9 GPa. Rupture stress computed after 21 tests, treated with the Weibull statistical theory, gave Weibull material parameters σ0 = 2237 MPa, with a Weibull modulus m = 5.1.
Table S2 from Purinostat Mesylate Is a Uniquely Potent and Selective Inhibitor of HDACs for the Treatment of <i>BCR-ABL</i>–Induced B-Cell Acute Lymphoblastic Leukemia

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

<p>IC50 values of PM and LBH589 against various hematological tumor cell lines.</p>