jimnoneill/paper-to-field-training huggingface dataset:
Value of CysC combined with RBP in the early renal damage evaluation in cancer chemotherapy

Field: Medicine (Health Sciences)

Objective To investigate the value of serum cysteine protease inhibitors C( CysC) combined with retinol binding protein( RBP) in the evaluation of early renal damage in cancer chemotherapy. Methods The clinical data of 50 cancer patients in Wuyang central hospital from January 2012 to January 2014 were retrospectively analyzed. Results BUN,Cr,CysC,RBP levels of the observation group were significantly higher than those of the control group( P 0. 05); BUN,Cr,CysC levels of gastrointestinal cancer patients were significantly higher than those of the control group( P 0. 05),but there was no significant difference in RBP concentration between the two groups( P 0. 05); The positive rate of BUN,Cr,CysC,RBP,CysC + RBP concentrations reached diagnostic criteria of the observation group was 8%( 4 /50),10%( 5 /50),88%( 44 /50),82%( 41 /50) and92%( 46 /50),which was significantly higher than that of the control group( P 0. 05). Conclusion CysC combined with RBP has high application value on the evaluation of early renal damage in cancer chemotherapy,so it is worthy of promoting.
Supporting data for manuscript "Late Paleozoic southward migration of the Dananhu arc in the Eastern Tianshan (NW China)"

Field: Earth and Planetary Sciences (Physical Sciences)

The data are the supporting information (SI.) for the manuscript “Devonian to Carboniferous-Permian southward migration of the Dananhu juvenile arc in the Eastern Tianshan (NW China)”. They contain: 1. SI. Table 1 “Zircon U-Pb ages of granites in the Dananhu arc in eastern Tianshan orogen, NW China” is U-Pb dating results of granitic rocks at the Kezier (K), Tuwu (Y) and Kanguer area (N) in the Dananhu arc. They reveal that granitic magmas became younger southwards in the growing Dananhu arc from 401-335 Ma in the Kezier area, to 334-315 Ma in the Tuwu area, and finally to 279-254 Ma in the Kanguer accretionary belt. 2. SI. Table 2 “The major (wt%), trace element (ppm) data of granites in the Dananhu arc in the eastern Tianshan orogen, NW China.” is the geochemical results of granitic rocks at the Kezier (K), Tuwu (Y) and Kanguer area (N) in the Dananhu arc. These granitic rocks include I-type granites, A-type granites, and adakite-like granites. The I-type granites (401-270 Ma) were generated by partial melting of juvenile intermediate or mafic crust. The A2-type granites (K7, 356 Ma) were products of strong fractional crystallization of mantle-derived magmas in an extensional setting. The Late Permian adakite-like granite (N8, 254 Ma) was derived from a depleted subducted oceanic slab. 3. SI. Table 3 “Zircon Lu-Hf isotopic data of granites in the Dananhu arc in the eastern Tianshan orogen, NW China.” is the zircon Lu-Hf isotopic results of the Kezier (K), Tuwu (Y) and Kanguer area (N) in the Dananhu arc. These crust-derived granitic rocks have relatively high positive zircons εHf(t) (+7.7-+19.6) values and young model age, suggesting that the Dananhu arc was a juvenile accretionary arc. 4. SI. Table 4 “Summary of published zircons ages of mafic-ultramific and granitic intrusions in the Dananhu arc.” is the published zircons ages of Devonian to Permian granitic intrusions at the Kezier (K), Tuwu (Y) and Kanguer area (N), and the early Permian mafic-ultramific complex in the Dananhu arc. The granitic rocks are younging southward from Kezier area, to Tuwu area and Kanguer accretionary complex. The early Permian mafic-ultramific complex emplaced in the Dananhu arc. SI. Analytical methods contain the zircon U-Pb dating, zircon Lu-Hf analyses, major element and trace element experiments, and Sr-Nd isotopic analyses analytical methods.
A New Peptide Coupling Reagent

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA New Peptide Coupling ReagentD. S. Kemp and S. W. ChienCite this: J. Am. Chem. Soc. 1967, 89, 11, 2743–2745Publication Date (Print):May 1, 1967Publication History Published online23 July 2002Published inissue 1 May 1967https://pubs.acs.org/doi/10.1021/ja00987a600https://doi.org/10.1021/ja00987a600research-articleACS PublicationsRequest reuse permissionsArticle Views257Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Preparation of environmentally friendly chitooligosaccharide via enzymatic hydrolysis using response surface methodology

Field: Chemical Engineering (Physical Sciences)

Abstract In this paper, chitooligosaccharide was prepared via the enzymatic hydrolysis of papain with chitosan as a raw material. The effects of pH, reaction time, temperature, and mass ratio of chitosan and enzyme on the product yield were analyzed. Single-factor and orthogonal experiments were used to determine the main factors affecting the reaction, and response surface methodology was used to optimize chitooligosaccharide preparation conditions. Optimum conditions were achieved at pH 4.50, with an enzymolysis time of 77.4 min, an enzymolysis temperature of 45 °C, a substrate concentration of 1.75% and an enzyme to chitosan weight ratio of 8.85. Under these conditions, the chitooligosaccharide yield reached 37.78%.
Assessing Entity Resolution techniques based on deep learning

Field: Computer Science (Physical Sciences)

Entity resolution (ER) is the task of identifying data instances referring to the same real-word entity. In this work, we study two major works that propose a deep-learning based solution for ER, namely DeepER and DeepMatcher. We re-evaluate their published results and benchmark it with the re-evaluated results of Magellan, an end-to-end entity resolution framework that uses classical machine learning. We then try to answer some questions mentioned in the sections below with the help of these results. We also report several interesting observations noted while reproducing these works. We highlight important but missing knowledge pertaining to generation of training and test sets. This information heavily influences the quality of evaluation results and is necessary to produce accurate authentic results. We conclude by presenting a study on ease of setting-up and rebuilding these solutions as an end-user.
[Mandatory regulations and standards regarding cosmetic botanic ingredients in major countries and regions].

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Cosmetics containing botanic ingredients have been used from thousands of years up to now in China. Because of the consumers' demand for health and beauty,the number of products about " botanic" have been growing rapidly in the cosmetics market,which has played an important role in upgrading the industry and enhancing the international competitiveness nowadays. Therefore,to strengthen the management about used botanic raw materials in cosmetics products and revise the application regulation of new raw materials has become an important work to ensure product quality,promote the healthy and stable development of cosmetic business. The article summarizes the related mandatory regulations and standards about botanic ingredients which used as activity function in major cosmetic business countries or regions. Furthermore,the information of botanic ingredients commonly used in non-special cosmetics notification and special cosmetic registration system were described to expect the better application and development.
An Empirical Investigation of the Economic Impacts of COVID-19: Micro-level Evidence from Europe

Field: Economics, Econometrics and Finance (Social Sciences)

This paper empirically investigates the economic impacts of COVID-19. Using firm-level data from Europe, we first analyze the statistics of how firms’ production, sales, workforce, expectations, and received government support were affected during 2020. We then examine the determinants of production reductions encountered by European firms during COVID-19 and compare between countries with different income levels. We find that both capacity utilization – to be specific, a firm’s output produced as a percentage of its maximum production capability – and employment size exert important influences on the likelihood of firms’ reduced production. Interestingly, receiving government support increases the likelihood of firms downsizing production in high-income countries, yet causes the opposite in low-income countries.
60 GHz UWB-over-fiber system for in-flight communications

Field: Engineering (Physical Sciences)

An impulse-radio ultra-wideband (IR-UWB) radio-over-fiber system targeting in-flight communications in the 60 GHz band is proposed and experimentally demonstrated. Baseband monocycles at 1.244 Gbit/s data rate with 3.8 GHz bandwidth are optically generated and up-converted in frequency to 57 GHz employing a Mach-Zehnder electro-optic modulator in nonlinear regime. The performance of the up-converted IR-UWB signal after the transmission in a cabin installation of 100 m of standard single-mode fiber is studied. The results show that excellent quality IR-UWB pulses are obtained after the in-cabin fiber transmission.
Mahabbah Love Rabiah Al Adawiyah's Discourse (Paul Ricoeur's Hermeneutic Study)

Field: Arts and Humanities (Social Sciences)

Da'wah is transcendental communication in doing good. Prophetic communication in da'wah communication shows that later a communicator or what is commonly called a preacher in da'wah communication will convey divine messages to the honeymooners/congregations or communicants. The three pillars as the characteristics of prophetic social science are amar ma'ruf (humanization), nahi munkar (liberation), and faith in Allah (transcendence). Hermeneutics has a foundation for understanding the birth of a text in a certain context or how a context gives rise to certain texts. In this study using qualitative methods with literature studies using paul ricoeur's hermeneutic analysis. The result of this research is that in Rabiah Al-Adawiyah's Mahabbah love poem, everyone's life will experience suffering. Rabiah's poem contains the prophetic values of amar ma'ruf (humanization), nahi munkar (liberation), and faith in Allah (transcendence). In the context of da'wah communication, Rabiah Al Adawiyah is a communicator. The source of communication that Rabiah took was from the upbringing she received. The communication messages conveyed by Rabiah aim for us to always worship and prioritize Allah. The da'wah medium used is the poetry delivered by Rabih in the book Mahabbah Cinta Rabiah Al Adawiyah, Jamaah or honey or communicants who receive the message are us, the readers of this book. The purpose of the activities carried out is to invite people like Rabiah who they are devoted to worship and really love Allah as their Lord. The feedback generated in this communication process is in a positive direction where no reader has expressed dissatisfaction with the writing in this book.
Advances in skin-derived antimicrobial peptides

Field: Medicine (Health Sciences)

The antimicrobial peptides (AMP) are essential components of innate immunity.Human skin-derived antimicrobial peptides mainly include β-defensins and cathelicidins family and they are widely expressed in skin keratinocytes and inflammatory cells.Skin-derived antimicrobial peptides play important roles in skin,such as protecting skin from infection,regulating the immune response of skin,enhancing wound healing and angiogenesis.Their expressions are influenced by many factors in vivo and in vitro and closely related to various inflammatory diseases of skin.They may also play an important role in wound healing of diabetes.

Key words:
Skin ; Antimicrobial peptides ; β-defensins ; Cathelicidins
Ethical and Surgical Dilemmas in Patients with Neglected Surgical Diseases Visiting a Field Hospital in a Zone of Recent Disaster

Field: Medicine (Health Sciences)

Abstract Object The massive typhoon Haiyan (Yolanda) ripped across the central Philippines on November 8, 2013, and damaged infrastructure including hospitals. The Israeli Defense Forces field hospital was directed by the Philippine authorities to Bogo City in the northern part of the island of Cebu, to assist the damaged local hospital. Hundreds of patients with neglected diseases sought for medical treatment which was merely out of reach for them. Our ethical dilemmas were whether to intervene, when the treatment we could offer was not the best possible. Methods Each patient had an electronic medical record that included diagnosis, management and aftercare instructions. We retrospectively reviewed all charts of patients. Results Over 200 patients presented with neglected chronic diseases (tuberculosis, goiter, hypertension and diabetes). We limited our intervention to extreme values of glucose and blood pressure. We had started anti‐tuberculosis medications, hoping that the patients will have an option to continue treatment. We examined 85 patients with a presumed diagnosis of malignancy. Without histopathology and advanced imaging modality, we performed palliative operations on three patients. Eighteen patients presented with inguinal hernia. We performed pure tissue repair on seven patients with large symptomatic hernias. We examined 12 children with cleft lip/palate and transferred two of them to Israel. We operated on one child with bilateral club feet. Out of 37 patients with pterygium, our ophthalmologist repaired the nine patients with the most severe vision disturbance. Conclusion Medical delegations to disaster areas should prepare a plan and appropriate measures to deal with non‐urgent diseases.
Arrogance, polarisation and arguing to win

Field: Arts and Humanities (Social Sciences)

A number of philosophers have defended the view that seemingly intellectually arrogant behaviours are epistemically beneficial. In this chapter I take issue with most of their conclusions. I argue, for example, that we should not expect steadfastness in one's belief in the face of contrary evidence nor overconfidence in one's own abilities to promote better evaluation of the available evidence resulting in good quality group judgement. These features of individual thinkers are, on the contrary, likely to lead groups to end up in stalemates and to polarise over issues. It is true that groups benefit from including members that, prior to discussion, hold diverse views. But disagreement benefits group judgement only when it is transient, rather than entrenched. That is, groups reach better quality conclusions when a number of diverse opinions are disseminated and evaluated fairly before reaching a consensus. If this is right, it would seem that individual qualities, such as open-mindedness and even-handedness about the epistemic value of opinions other than one's own, rather than steadfastness or overconfidence are conducive to better quality group judgement.
Influence of Pressure on Chemical Equilibria in Aqueous Systems - with Particular Reference to Seawater

Field: Chemistry (Physical Sciences)

Abstract Synopsis : The influence of pressure on chemical equilibria in aqueous solutions and the parameters that influence such equilibria are reviewed in this work. Particular emphasis is given to equilibria in seawater, including mineral dissolution, weak acid dissociation and metal ion complexation. Intended perspectives include the capabilities of predictive models to describe chemical equilibria in low temperature geochemical systems and the extent to which predictive models are constrained by direct observations. In context of the importance of pressure as a key variable controlling the pathways and fate of environmental chemicals, a need for further direct observations of chemical equilibria at high pressure, under conditions which are often challenging to the experimentalist, is evident.
Zooming in on Supernova 1987A at submillimetre wavelengths

Field: Physics and Astronomy (Physical Sciences)

Context. Supernova 1987A (SN 1987A) in the neighbouring Large Magellanic Cloud offers a superb opportunity to follow the evolution of a supernova and its remnant in unprecedented detail. Recently, far-infrared (far-IR) and sub-mm emission was detected from the direction of SN 1987A, which was interpreted as due to the emission from dust, possibly freshly synthesized in the SN ejecta. Aims. To better constrain the location and hence origin of the far-IR and sub-mm emission in SN 1987A, we have attempted to resolve the object in that part of the electro-magnetic spectrum. Methods. We observed SN 1987A during July–September 2011 with the Atacama Pathfinder EXperiment (APEX), at a wavelength of 350 μm with the Submillimetre APEX BOlometer CAmera (SABOCA) and at 870 μm with the Large APEX BOlometer CAmera (LABOCA). The 350-μm image has superior angular resolution (8′′) over that of the Herschel Space Observatory 350-μm image (25′′). The 870-μm observation (at 20′′ resolution) is a repetition of a similar observation made in 2007. Results. In both images, at 350 and 870 μm, emission is detected from SN 1987A, and the source is unresolved. The flux densities in the new (2011) measurements are consistent with those measured before with Herschel at 350 μm (in 2010) and with APEX at 870 μm (in 2007). A higher dust temperature (≈33 K) and lower dust mass might be possible than what was previously thought. Conclusions. The new measurements, at the highest angular resolution achieved so far at far-IR and sub-mm wavelengths, strengthen the constraints on the location of the emission, which is thought to be close to the site of SN 1987A and its circumstellar ring structures. These measurements set the stage for upcoming observations at even higher angular resolution with the Atacama Large Millimeter Array (ALMA).
Défense et illustration du Néolithique récent du Languedoc central, plus particulièrement de celui de la région Saint-Pons-Lodève

Field: Arts and Humanities (Social Sciences)

The Late Neolithic in central Languedoc (the "Saintponien" in particular) has until now mostly been identified with reserve, confused with diachronic fades and situated indistinctly in the chronological synopsis of the Languedocian Neolithic. However, this Neolithic is quite specific. It has a plentiful lithic industry, with an asymmetrical arrowhead which is the main diagnostic artefact, and a rich bone and antler industry, in a regional environment where lithic and bone industries are sometimes lacking. Some antler artefacts could be interpreted as the "objects " depicted on the statue-menhirs, since nothing prevents the latter being attributed, at least in part, to this group. Without metal, the group is well- defined chronologically (around the second half of the 4th millennium ВС), stratigraphically situated between the Chassey and Véraza cultures. We wish to point out that the "Saintponien " has a typical, good-quality pottery, which has not been studied in this article because it is currently the subject of a thesis.
MENGGALI KEINDAHAN KEBERAGAMAN: NILAI-NILAI MULTIKULTURAL PPTQ BAITUL ABIDIN DARUSSALAM KALIBEBER WONOSOBO

Field: Social Sciences (Social Sciences)

This article examines the implementation of multicultural values at PPTQ (Pondok Pesantren Tahfidzul Qur’an) Baitul Abidin Darussalam, Kalibeber, Wonosobo. Using a qualitative approach, this study aims to explore how the pesantren integrates cultural, religious, and ethnic diversity into the education of its students. The findings indicate that the multicultural values at this PPTQ have successfully created an inclusive and harmonious environment. The students are taught to respect differences and build tolerance, which allows them to live harmoniously in the midst of diversity. The article concludes that the application of multicultural values in pesantren can serve as an effective educational model in shaping tolerant and broad-minded students. It provides recommendations for pesantren managers and educators to continue strengthening multicultural values in the daily activities of students. This reinforcement is crucial for preparing students to face rapid social changes. Therefore, the multicultural values applied at PPTQ Baitul Abidin Darussalam can serve as an example for other educational institutions in building a harmonious and inclusive society. ABSTRAKArtikel ini mengkaji penerapan nilai-nilai multikultural di PPTQ (Pondok Pesantren Tahfidzul Qur’an) Baitul Abidin Darussalam, Kalibeber, Wonosobo. Melalui pendekatan kualitatif, penelitian ini bertujuan untuk mengungkap bagaimana pesantren ini mengintegrasikan keberagaman budaya, agama, dan etnis dalam pendidikan santri. Hasil penelitian menunjukkan bahwa nilai-nilai multikultural di PPTQ ini berhasil menciptakan lingkungan yang inklusif dan harmonis. Para santri diajarkan untuk menghargai perbedaan dan membangun toleransi, yang memungkinkan mereka untuk hidup berdampingan secara harmonis di tengah keberagaman. Artikel ini menyimpulkan bahwa penerapan nilai-nilai multikultural di lingkungan pesantren dapat menjadi model pendidikan yang efektif dalam membentuk karakter santri yang toleran dan berwawasan luas. Artikel ini memberikan rekomendasi bagi pengelola pesantren dan pendidik untuk terus memperkuat nilai-nilai multikultural dalam kegiatan harian santri. Penguatan ini penting untuk mempersiapkan santri menghadapi perubahan sosial yang cepat. Dengan demikian, nilai-nilai multikultural yang diterapkan di PPTQ Baitul Abidin Darussalam dapat berfungsi sebagai contoh bagi lembaga pendidikan lainnya dalam membangun masyarakat yang harmonis dan inklusif.
Non-Lethal Weapons for Use Rediofrequency/Microwave Energy for Stunning/Immobilization

Field: Engineering (Physical Sciences)

Abstract : This basic research initiative is geared ultimately toward developing effective and safe non-lethal technologies that alter skeletal muscle contraction and/or neural functioning via radiofrequency (RF)/microwave (MW) electromagnetic radiation. Major accomplishments included: (1) near completion of studies examining the effect of 1 to 6 GHz MW fields on catecholamine release from chromaffin cells; (2) initiating studies using a novel exposure system for real-time imaging of intracellular effects in chromaffin cells in response to high electric field RF/MW pulse modulated radiation, broadband Gaussian pulses or RF/MW modulated Gaussian pulses with the frequency spectrum centered in the band 0.75-6 GHz; (3) completion of studies on the effect of 0.75 to 1 GHz RF fields on skeletal muscle contraction using fixed frequencies and just recently implementing frequency sweep paradigms; (4) initiation of studies to examine the effect of nanosecond electric pulses of high intensity on catecholamine release from chromaffin cells. The research, which was presented at four international meetings and culminated in three peer-reviewed papers, has been transitioned into AFOSR grant FA9550-07-1-0592.