jimnoneill/paper-to-field-training huggingface dataset:
Talent acquisition and its role in enhancing employee satisfaction and retention in star-rated hotels

Field: Business, Management and Accounting (Social Sciences)

Talent acquisition is a fundamental aspect of human resource management in star-rated hotels, offering distinct advantages such as attracting highly skilled candidates, ensuring a competitive edge, and enhancing overall service quality. The effectiveness of these practices lies in their ability to align with organizational goals, create a strong employer brand, and streamline the hiring process. This directly impacts employee satisfaction and retention, as effective talent acquisition practices lead to higher job satisfaction, increased engagement, and a more committed workforce. Study on this is essential to understand how effective recruitment and retention strategies impact employee satisfaction and retention, which are critical for maintaining high service standards in the competitive hospitality industry. Effective talent acquisition strategies can significantly lower turnover rates and build long-term employee loyalty, ultimately driving operational success and enhancing guest pleasure in the hotel industry. Study is to investigate the connection between talent acquisition practices, employee satisfaction, and retention in star rated hotels in Kerala. The study employed a quantitative research design, utilizing Statistical Package for the Social Sciences (SPSS) to analyze the data collected through structured questionnaires distributed to employees in star rated hotels. The results underscore the importance of a strategic approach to talent acquisition in driving employee retention and sustaining competitive advantage in hotel industry.
A study of the neurological disorder associated with acute haemorrhagic conjunctivitis due to enterovirus 70.

Field: Medicine (Health Sciences)

Ninety cases of the neurological manifestations associated with acute haemorrhagic conjunctivitis caused by Enterovirus 70 (EV 70) are reported. The patients were seen during the widespread epidemics in 1971 and 1981. Male adults were predominantly affected by a "polio-like" paralysis of the limbs and/or cranial nerves. Root pains were often complained of early in the disease. In the absence of a necropsy, clinical and neurophysiological examinations helped to localise the lesions. Significant antibody titres against EV 70 were demonstrated in the serum and more relevantly in the CSF. Though other viruses can cause sporadic and epidemic conjunctivitis and similar paralysis independently, the combination of a haemorrhagic conjunctivitis and a neurological disease mostly simulating poliomyelitis is caused by EV 70 alone. It is therefore suggested that this combination be called "Enterovirus 70 disease". Because of its neurovirulence, it is important to identify this virus at the very beginning of an epidemic of conjunctivitis, so as to limit its spread by strict public health measures.
ChemInform Abstract: Synthesis and Catalytic Activity of a New Class of Cyclophosphazenic Polypodands.

Field: Chemistry (Physical Sciences)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Circulating AR copy number and outcome to enzalutamide in patients with metastatic castration-resistant prostate cancer after docetaxel.

Field: Medicine (Health Sciences)

e16583 Background: Enzalutamide is a new anti-androgen with a great affinity for androgen receptor (AR). We aimed at identifying circulating AR copy number (CN) gain as non-invasive biomarker for outcome prediction to enzalutamide. Methods: Fifty-nine castration-resistant prostate cancer (CRPC) patients (pts) treated with enzalutamide 160 mg daily after docetaxel were evaluated. Twenty-eight of 59 (47%) pts previously received abiraterone. AR CN was evaluated in the serum collected before the start of treatment with real-time PCR with TaqMan assays and digital PCR analysis. Progressive disease was defined on the basis of Prostate Cancer Working Group 2 criteria. Univariate and multivariate Cox regression models addressed potential predictors of progression-free survival (PFS) and overall survival (OS). Results: AR CN gain was found in 21 of 59 (36%) pts. Median baseline PSA, alkaline phosphatase and LDH levels were higher in the AR CN gained group (p= 0.007, p= 0.003, p= 0.0009, respectively). A PSA decline ≥ 50% was reported in 4 of 21 (19%) pts with AR CN gain and 14 of 38 (37%) without AR CN gain (p= 0.260). The median PFS of pts with AR CN gain was 2.4 months (95% CI: 1.9-3.2) vs. 4.0 months (95% CI: 3.0-6.5) of those with no AR CN gain (p= 0.0004). The median OS of pts with AR CN gain was 6.1 months (95% CI: 3.4-8.6) vs. 14.1 months (95% CI: 8.2-20.5) of those with no AR CN gain (p= 0.0003). Univariate analysis showed a significant impact on PFS and OS for previous abiraterone, PSA decline ≥ 50%, and AR CN. At multivariate analysis, only PSA decline ≥ 50%, and AR CN showed a significant association with PFS (p =0.003 and p= 0.0006, respectively) and OS (p= 0.002 and p= 0.019, respectively). Conclusions: Detection of circulating AR CN gain is a potentially promising non-invasive biomarker for outcome prediction to enzalutamide treatment in CRPC pts.
Analgesic and anti-inflammatory activity of the aqueous extract ofRheedia longifolia Planch & Triana

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Rheedia longifolia Planch et Triana belongs to the Clusiaceae family.
This plant is widely distributed in Brazil, but its chemical and
pharmacological properties have not yet been studied. We report here
that leaves aqueous extract of R. longifolia (LAE) shows analgesic and
anti-inflammatory effects. Oral or intraperitoneal administration of
this extract dose-dependently inhibited the abdominal constrictions
induced by acetic acid in mice. The analgesic effect and the duration
of action were similar to those observed with sodium diclofenac, a
classical non-steroidal analgesic. In addition to the effect seen in
the abdominal constriction model, LAE was also able to inhibit the
hyperalgesia induced by lipopolysaccharide from gram-negative bacteria
(LPS) in rats. We also found that R. longifolia LAE inhibited an
inflammatory reaction induced by LPS in the pleural cavity of mice.
Acute toxicity was evaluated in mice treated with the extract for seven
days with 50 mg/kg/day. Neither death, nor alterations in weight, blood
leukocyte counts or hematocrit were noted. Our results suggest that
aqueous extract from R. longifolia leaves has analgesic and
anti-inflammatory activity with minimal toxicity and are therefore
endowed with a potential for pharmacological control of pain and
inflammation.
Verification of Multiagent Systems via Ordered Binary Decision Diagrams: An Algorithm and Its Implementation

Field: Computer Science (Physical Sciences)

We investigate the problem of the verification of epistemic properties of multiagent systems via model checking. Specifically, we extend and adapt methods based on ordered binary decision diagrams, a mainstream verification technique in reactive systems. We provide an algorithm, and present a software package that implements it. We discuss the software and benchmark it by means of a standard example in the literature, the dining cryptographers.
From Settlement to Divorce: An Islamic Judicial Practice in Burkina Faso

Field: Social Sciences (Social Sciences)

Abstract Islamic reconciliation spaces in Burkina Faso take a significant place within the plurality of informal agencies of conflict resolution. Yet this place remains barely visible. This article studies the forms of Islamic justice in the country: it shows how the Islamic authorities dealing with the resolution of family conflicts tend to integrate the Islamic norms with local practices and the demands of justiciable persons. In the Sufi rural environment, the concept of sulufu expresses the need for a friendly conciliation that diverges from literalistic reading of the Quran. In town, the role of the ‘settlement’ plays against the proliferation of divorce: while the Islamic elites agree that the divorce is authorized within the Muslim law, in practice they refuse to endorse it. This shows the force of social injunctions in relation to marriage and to the indissolubility of the couple.
Managing Chronic Back Pain Using Individual Mindfulness Techniques

Field: Health Professions (Health Sciences)

Research has proven that mindfulness is beneficial for individuals with chronic back pain however structured programs are not helpful for all. This thesis proposes that mindfulness can be a personal healing journey, one that is directed by the individual. The current study examined the effectiveness of mindfulness programs in interviews with two people dealing with chronic back pain. Outcomes of the study support the proposal that mindfulness is as individual as the person who defines it. Mindfulness can be used as an empowerment tool, emerging from negativity to a more positive lifestyle. The path to healing is unique, however, this study supports that success can be achieved by setting goals and having a positive mindset.
"Will the Real Israel Please Stand Up?" Archaeology and Israelite Historiography: Part I

Field: Arts and Humanities (Social Sciences)

This article reviews a number of recent histories of ancient Israel, both in terms of general historiographical issues and of their use of archaeological data. The underlying questions may be: (1) "Is it any longer possible to write a history of ancient Israel based on texts alone?" and (2) "What kind of history do we want, or think possible?"
A Vision for Future Upstream Technologies

Field: Energy (Physical Sciences)

This paper presents my vision of the most influential technologies for the next two decades. Unabated<br>global demand for energy will translate into growing demand for traditional hydrocarbon resources.<br>This growing demand represents a significant challenge to which the industry must respond. Several<br>companies have announced ambitious expansion plans for the next several years. However, demand<br>growth is expected to be a long-term phenomenon, for which new technologies must be developed to<br>increase the effectiveness by which hydrocarbon resources are found, developed, and produced.<br>The paper briefly reviews technologies that I consider the most influential in the past decades, namely<br>3Dseismic data, horizontal drilling, and geosteering. Each of these technologies has had a profound<br>effect on the industry, emerging from humble beginnings to mainstream applications. Next, I discuss<br>my vision of the potentially most influential future technologies. These technologies include extremereservoir-<br>contact wells, smart inflow-control devices, autonomous fields, passive-seismic monitoring,<br>gigacell simulation, smart fluids, bionic wells, and nanorobots. Though most of these are just dreams,<br>significant strides that have been made to achieve them are highlighted.
ESR SPECTRA AND STRUCTURES OF [Cu(B15C5)(H2O)2](ClO4)2 IN [Mg(B15C5)(H2O)2](ClO4)2 CRYSTAL AND IN FROZEN 60% HCLO4; VIBRONIC INTERACTION THEORY

Field: Chemistry (Physical Sciences)

Abstract Obvious differences in 3dz 2 ground-state ESR spectra observed at 77K were detected between a powder sample of Cu(II) doped in [Mg(B15C5)(H2O)2](ClO4)2 single crystal and a Cu(B15C5) complex in 60% HClO4. An X-ray diffraction analysis of [Mg(B15C5)(H2O)2](ClO4)2 demonstrated that the complex takes on a seven-coordinate pentagonal bipyramidal geometry and the axial ligands are also H2O molecules, which is similar to [Cu(B15C5)(H2O)2](ClO4)2. Differences in ESR spectra are qualitatively explained as being due to changes in coordination bond distances and angles for both cases, based on vibronic interaction theory. The ground-state Kramers doublet wavefunctions were calculated and reveal an increase of admixture of 3dx 2_y 2 and 3dxy orbitals into a 3dz 2 ground-state for the Cu(II) ion doped in the crystal.
The Role of Leadership on Emotion Regulation, Service Delivery, and Health: A Multi-Level Study

Field: Business, Management and Accounting (Social Sciences)

Prior research on emotional labor has primarily been conducted at the individual level. In this paper, we examine a model of unit employee emotional labor and its relationships with unit LMX and LMX differentiation as well as with unit employee outcomes. Results from 701 employees and 117 managers from 117 branches of a real-estate company in Taiwan showed that deep acting exhibited a higher consistency and agreement at the unit level than surface acting. Further, we found that unit LMX was positively related to unit employee deep acting, and that LMX differentiation moderated the effect of unit LMX on surface acting in such a way that the relationship was more negative when LMX differentiation was high. In addition, unit surface acting was negatively related to supervisor-rated employee customer-oriented behavior and positively related to employee somatic symptoms.
Induction in transgenic mice of HLA-A2.1-restricted cytotoxic T cells specific for a peptide sequence from a mutated p21ras protein

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

SUMMARY Cytotoxic T cells (CTL) recognize short peptides that are derived from the proteolysis of endogenous cellular proteins and presented on the cell surface as a complex with MHC class I molecules. CTL can recognize single amino acid substitutions in proteins, including those involved in malignant transformation. The mutated sequence of an oncogene may be presented on the cell surface as a peptide, and thus represents a potential target antigen for tumour therapy. The p21ras gene is mutated in a wide variety of tumours and since the transforming mutations result in amino acid substitutions at positions 12, 13 and 61 of the protein, a limited number of ras peptides could potentially be used in the treatment of a wide variety of malignancies. A common substitution is Val for Gly at position 12 of p21ras. In this study, we show that the peptide sequence from position 5 to position 14 with Val at position 12—ras p5–14 (Val-12)—has a motif which allows it to bind to HLA-A2.1. HLA-A2.1-restricted ras p5–14 (Val-12)-specific CTL were induced in mice transgenic for both HLA-A2.1 and human β2-microglobulin after in vivo priming with the peptide. The murine CTL could recognize the ras p5–14 (Val-12) peptide when they were presented on both murine and human target cells bearing HLA-A2.1. No cross-reactivity was observed with the native peptide ras p5–14 (Gly-12), and this peptide was not immunogenic in HLA-A2.1 transgenic mice. This represents an interesting model for the study of an HLA-restricted CD8 cytotoxic T cell response to a defined tumour antigen in vivo.
Criteria for Pathologic Sampling of Gallbladder Specimens

Field: Medicine (Health Sciences)

To the Editor

The article by Renshaw and Gould1 brings up a question that not only is challenging for our field but also is an issue with far-reaching implications on how sampling of specimens will be performed in the cost containment era with upcoming health care changes in the United States and the world. The authors advocate that, in the pathologic sampling of gallbladder (GB) specimens, taking additional sections to rule out a neoplastic process may not be justifiable. We believe that the authors have a valid point, but this approach reflects only one side of this challenging equation. Let us take this approach to the extreme: annually, approximately 1 million cholecystectomies are performed in the United States, with an estimated 9,000 gallbladder cancer (GBC) diagnoses.2 Therefore, even if we stopped examining GBs pathologically altogether, our “miss” rate of a GBC would be only 0.04%, which some may consider negligible and may even regard as a reasonable health care policy considering the upcoming finances. We suspect, however, that those patients with GBC may have another stance on this issue and may question the justification for the hundreds of billions of dollars that continue to be spent on identifying clinically silent prostate cancer with minimal or no impact on survival from the global health care perspective.3,4

Accountable care issues and health care policies aside, in a discussion about sampling of GBs, one thing that needs to be kept in the forefront is the fact that GBC is highly insidious, notorious for being “inapparent” both clinically and at the macroscopic level. In fact, even in experts’ hands that perform careful macroscopic and complete microscopic evaluation of the GBs, more than one-third of the advanced GBCs (pT2 and above) are missed during gross examination,5–7 and …
Excellent Clinical Long-Term Outcomes of Kidney Transplantation From Small Pediatric Donors (Age ≤ 5 Years) Despite Early Hyperfiltration Injury

Field: Medicine (Health Sciences)

Background: The use of small pediatric donors (age ≤ 5 years and body weight < 20kg) for adult transplant recipients is still regarded controversially in terms of early complications, long-term outcomes, and development of hyperfiltration injury due to body size mismatch. Objective: To investigate long-term outcomes of adult renal allograft recipients receiving a kidney from small pediatric donor (SPD) in terms of kidney function and early features of hyperfiltration injury such as histological changes and proteinuria. Design: Retrospective, single center study. Settings: Transplant center of the University Hospital of Basel, Switzerland. Patients: Adult renal allograft recipients receiving a kidney from a small pediatric donor at our center between 2005 and 2017. Methods: The outcome of 47 transplants from SPD were compared with 153 kidney transplants from deceased-standard criteria donors (SCD) occurring during the same time period. Incidence of clinical signs of hyperfiltration injury (eg, proteinuria) was investigated. According to our policy, surveillance biopsies were taken at 3 and 6 months post-transplant and were evaluated in terms of signs of hyperfiltration injury. Results: At a median follow-up of 2.3 years post-transplant, death-censored graft survival of SPD was comparable to transplants from SCD (94% vs 93%; P = .54). Furthermore, allograft function at last follow-up (estimated glomerular filtration rate–Modification of Diet in Renal Disease) was significantly higher in pediatric transplant (80 vs 55 ml/min/1.73 m 2 , P = .002). We found histological signs of early hyperfiltration injury in 55% of SPD. There was an equally low proteinuria in both groups during follow-up. Limitations: It is a single center and retrospective observational study with small sample size. The outcomes were investigated in a well-selected population of recipients with low body mass index, low immunological risk, and well-controlled hypertension and was not compared with equal selected group of recipients. Conclusions: Early histological and clinical signs of hyperfiltration injury in SPD is frequent. Despite the hyperfiltration injury, there is an equal allograft survival and even superior allograft function in SPD compared with SCD during follow-up. This observation supports the concept of high adaptive capacity of pediatric donor kidneys.
Exposure and inhaling of microplastics: An evidence of cause of cancer

Field: Environmental Science (Physical Sciences)

Microplastics are defined as plastic particles less than 5 millimeters in diameter and can be categorized as primary and secondary microplastics. Microplastics are widely distributed in oceans, freshwater, soil, atmosphere, food chain and living organisms. Micro(nano) plastics enter the human body through the food chain, leading to their accumulation in the body. Different types of microplastics have been found in human placenta, meconium, breast milk, blood, and feces. The ingestion of microplastics may lead to impaired physiological functions in humans. Micro-and nanoplastics can serve as a source of carcinogenic or mutagenic substances, potentially causing DNA damage that can lead to carcinogenesis, the development of cancerous tumors. Currently, much remains unknown about the specific mechanisms of toxicity of micro(nano)plastics to living organisms, especially human cells. Although there are still many challenges to the direct application of micro(nano)plastics in cancer therapy, their unique physicochemical properties provide new ideas for cancer treatment. Plastics are highly persistent in nature due to which their degradation occurs at a slower rate and their accumulation at a faster pace. Plastics comprise polymers such as polyethylene (PE), polystyrene (PS), polypropylene (PP), polyethylene terephthalate (PET) and polyvinyl chloride (PVC). They are distributed across the aquatic systems, land surface, inside biological organisms, human consumables and even in the air.
Type I interferon signalling in the intestinal epithelium affects Paneth cells, microbial ecology and epithelial regeneration

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Objective Intestinal epithelial cells (IECs) at the internal/external interface orchestrate the mucosal immune response. Paneth cells secrete antimicrobial peptides and inflammatory mediators, protect from pathogens and shape the commensal microbiota. Prompted by the genetic association of the locus harbouring the type I interferon (IFN) receptor ( IFNAR1 ) with Crohn's disease, and a transcriptional signature for type I IFN signalling in Paneth cells, we studied the function of IFNAR1 in IECs. Design Type I IFN signalling was studied in mice with conditional deletion of Ifnar1 in IECs. Phenotype was characterised at baseline, and gut microbiota composition was assessed by 16S rDNA ribotyping. The role of IFNAR1 was also investigated in experimental colitis induced by dextran sodium sulfate (DSS) and colitis-associated cancer induced by DSS in conjunction with azoxymethane (AOM). Results Ifnar1 −/−(IEC) mice displayed expansion of Paneth cell numbers and epithelial hyperproliferation compared with Ifnar1 -sufficient littermates. While Ifnar1 −/−(IEC) mice did not exhibit spontaneous inflammation or increased severity in DSS colitis compared with Ifnar1 +/+(IEC) mice, they exhibited an increased tumour burden in the AOM/DSS model. Both hyperproliferation and tumour promotion were dependent on the microbial flora, as the differences between genotypes were marked upon separately housing mice, but disappeared when Ifnar1 −/−(IEC) and Ifnar1 +/+(IEC) mice were co-housed. Accordingly, ribotyping revealed marked differences between Ifnar1 −/−(IEC) and Ifnar1 +/+(IEC) mice that where diminished upon co-housing. Conclusions IFNAR1 in IECs, and Paneth cells in particular, contributes to the regulation of the host–microbiota relationship, with consequences for intestinal regeneration and colitis-associated tumour formation.