jimnoneill/paper-to-field-training huggingface dataset:
BUREAU OF LEGAL MEDICINE AND LEGISLATION

Field: Medicine (Health Sciences)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Supplementary Figure S2 from LIMD2 Is a Small LIM-Only Protein Overexpressed in Metastatic Lesions That Regulates Cell Motility and Tumor Progression by Directly Binding to and Activating the Integrin-Linked Kinase

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

<p>Total mRNA was extracted from cancer cell lines using RNeasy Mini Kit (Qiagen).</p>
Gas-liquid equilibrium of oxygen-carbon dioxide system

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGas-liquid equilibrium of oxygen-carbon dioxide systemAage Fredenslund, Joergen Mollerup, and Ole PerssonCite this: J. Chem. Eng. Data 1972, 17, 4, 440–443Publication Date (Print):October 1, 1972Publication History Published online1 May 2002Published inissue 1 October 1972https://pubs.acs.org/doi/10.1021/je60055a019https://doi.org/10.1021/je60055a019research-articleACS PublicationsRequest reuse permissionsArticle Views240Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Homelessness and institutional settings: an overview and an odyssey

Field: Social Sciences (Social Sciences)

This chapter demonstrates how institutional settings are bulwarks in societal responses to homelessness. We begin with an account of one man’s odyssey, spanning more than three decades, of homelessness and stints in an array of institutional settings: shelters, jails, prisons, drug treatment facilities, and veterans services. We then deconstruct this oral history to show how such institutions function as surrogates for housing rather than pathways for regaining housing, and how in doing so they incur considerable public expense in their sheltering and caring for the homeless population. We situate this reliance on institutions in the US in both an historical context and in current policy debate, where institutional primacy currently manifests itself as the centerpiece for a conservative constituency that is resistant to the idea that homelessness is best resolved through housing-oriented responses.
History, current status and future prospects of uneven-aged forest management in the Dinaric region: an overview

Field: Agricultural and Biological Sciences (Life Sciences)

The development of uneven-aged forest management in the Dinaric region (north-west Balkans) is reviewed. Uneven-aged silviculture has been the major silvicultural system in the region since regular forest management began in the second half of the nineteenth century. Regular forest management in former virgin forest areas began as selection forest management mainly because of the awareness of the importance of multilayered continuous forest cover for preventing soil erosion on carbonate substrate. The observed period of more than 100 years has seen several changes to uneven-aged forest management ranging from the complete domination of rigid selection forest management to the gradual acceptance and eventual domination of the irregular shelterwood system and finally to the acceptance of freestyle forest management, which is presently practiced in the Slovenian part of the Dinaric region. Freestyle silviculture combines practices of different silvicultural systems. By using this system, consideration for site conditions and heterogeneous stand dynamics at small spatial scales is possible. In the observed period, some stand parameters of Dinaric forests have changed substantially. Growing stock has increased significantly, the number of large-diameter trees has increased and alternation of the main tree species (silver fir and European beech) has occurred. The development of uneven-aged forest management is described and its prospects are discussed.
Neonatal Insulin Secretion and Persistent Hyperinsulinemia of Infancy

Field: Medicine (Health Sciences)

After completing this article, readers should be able to:

1. Delineate the clinical findings associated with persistent hyperinsulinemia of infancy.

2. Identify the primary classifications of persistent hyperinsulinemia of infancy.

3. Describe the major characteristics of the form of disease associated with loss of KATP channel function.

4. List the genes responsible for KATP channel activity.

5. Delineate potential clinical tools for differentiating focal and diffuse forms of persistent hyperinsulinemia of infancy.

An experimental approach based on genetic studies has offered new insights into the pathophysiology of persistent hyperinsulinemia of infancy. This review highlights these advances, with special emphasis on the forms of hyperinsulinemia that are associated with defects of the adenosine triphosphate (ATP)-dependent potassium (KATP) channel, a key regulator of insulin secretion in the pancreatic islets.

Persistent hyperinsulinemia of infancy has been known as nesidioblastosis, persistent hyperinsulinemic hypoglycemia of infancy, and familial hyperinsulinism since its initial recognition as a clinical entity in the 1950s. More prevalent forms of hypoglycemia that are transitory and occur in the immediate newborn period must be differentiated from persistent hyperinsulinemia of infancy, which is defined by inappropriate insulin secretion in the presence of profound hypoglycemia. The characteristic associated clinical findings (Table 1⇓ ), including inappropriate glucose-to-insulin ratios, suppression of ketone body production, glucose utilization rates that are threefold the norm, and a glycemic response to glucagon, all can be attributed to excessive levels of circulating insulin.

View this table:

Table 1.
Diagnostic Features of Persistent Hyperinsulinemia of Infancy

Persistent hyperinsulinemia of infancy originally was defined as the pathologic entity nesidioblastosis, which denoted nests of islets in close proximity to pancreatic ductules and presumed an abnormality of neoislet formation as the etiology of the excessive insulin secretion. The pathology literature related to this syndrome has been confusing and at times controversial, but as understanding of pathophysiology improves, so does the ability to …
Tissue Response to Schistosoma mansoni in Second Generation Snails from a Cross between Two Strains of Australorbis glabratus

Field: Agricultural and Biological Sciences (Life Sciences)

KOFOID, C. A. AND JOHNSTONE, H. G. 1929 The cultivation of Endamoeba gingivalis (Gros) from the human mouth. Amer. J. Publ. Health 19: 549-552. LAMY, L. 1948 Obtention d'une culture bacteriologiquement pure d'amibes parasites pathogenes (Entamoeba invadens, Rodhain), ne comportant aucune addition de germes bacteriens morts, ni d'aucun extrait microbien. C. R. Acad. Sci., Paris 226: 2021-2022. 1951 La culture pure des amibes parasites. J. Med. Bordeaux 128: 253-256. MILLER, M. J. 1951 A method for in vitro culture of Entamoeba invadens free from bacteria. Canad. J. Comp. Med. 15: 268. NAKAMURA, M. 1952 Substitution of an enzyme preparation for Trypanosoma cruzi in cultures of Endamoeba histolytica. Kitasato Arch. Exp. Med. 25: 43-46. AND ANDERSON, H. H. 1951 Effect of heat-treatment on the respiration of Trypanosoma cruzi used for the cultivation of Endamoeba histolytica. Amer. J. Trop. Med. 31: 438-441.
Epilepsy and autism spectrum disorders

Field: Neuroscience (Life Sciences)

For over 30 years, multiple studies have demonstrated that children with autism spectrum disorders (ASD) are at high risk for developing epilepsy, with the highest risk in those with intellectual disability. This risk continues into the second and third decades of life.1,2 However, not until recently have investigators asked the question: How often does ASD occur in epilepsy? Several studies demonstrated that neurodevelopmental disorders such as ASD occur more frequently in epilepsy, with the highest risk in those with in those with cognitive impairments and frequent seizures. The emerging concept is that there is a bidirectional relationship between epilepsy and ASD. A critical question to understand relates to the mechanisms that link epilepsy to ASD, as this may lead to interventions that can ultimately improve quality of life for individuals with epilepsy associated with ASD.
NMR Foodomics

Field: Agricultural and Biological Sciences (Life Sciences)

In modern science and technology, it is often underappreciated that foods from a chemical, physical and biological perspective are complex multifactorial systems that are extremely difficult to measure and evaluate. From a chemical perspective, foods are complex chemical mixtures of heterogeneous classes of molecules dominated by the four basic food constituents: water, fats, carbohydrates and proteins. To add further complexity, food manufacturing processes often consists of a series of unit operations that are designed to induce certain functional traits to the food materials being processed. This chapter will seek to give an overview of the possibilities and limitations of using the 1H NMR metabolomics platform to study food and food systems (foodomics). The merger of food science with advanced analytical tools, such as high-resolution NMR and multivariate data analysis chemometrics, has proven to be tremendously successful. The “weak whispers” from the protons in our food have been proven to contain a plethora of information about our aliments and to be useful in multiple applications within advanced quality control, which is not possible with existing optical spectroscopies, in particular for addressing the multiple and systemic issues related to safety and quality of food.
Peer Review #2 of "Clinical characteristics and prognostic nomogram analysis of patients with dual primary cancers with first gastric cancer: a retrospective study in China (v0.2)"

Field: Medicine (Health Sciences)

Background: With the improvement in diagnosis and treatment of gastric cancer (GC), the survival time of patients has been gradually prolonged.However, these survivors are at increased risk for other diseases, including second primary cancers (SPCs).Currently, there remain few central studies concerning double primary cancers with first gastric cancer (DPCFGC).Thus, this study aimed to investigate these patients' clinical characteristics and perform prognostic nomogram analysis.Methods: The clinical data of 78 DPCFGC patients were retrospectively collected and analyzed through the hospital electronic medical record system.Univariate and multivariate Cox regression analyses were performed to screen independent risk factors , based on which the prognostic nomogram was further constructed and validated using the R software package.Finally, Kaplan-Meier curves were plotted to explore the association of overall survival ( OS) with prognostic factors and the model .Results: The prevalence of DPCFGC was 0.86%, of which the proportions of synchronous and metachronous patients were 47.44% and 52.56% , respectively; 65.38% (51/78) and 34.62% (27/78) of patients were male and female, respectively.The median age at GC and SPC diagnosis was 63 and 65 years, respectively, and 52.57% of GC patients developed SPCs within 1 year.The top three SPCs were in the esophagus (19.24%), colon (16.67%), and rectum (15.39%).The most common features of GC and SPCs were adenocarcinoma, poorly and moderately differentiated histology, and pathological stages I and II.The radical resection rate of GC was significantly lower in synchronous patients than in metachronous patients (45.94% vs. 100.00%,P < 0.001), but no significant difference was noted in the radical resection rate of SPCs (35.13% vs. 46.34%,P = 0.315).The OS of DPCFGC patients was 31.03 ± 4.14 months.The pathological stage of GC and SPCs, whether to operate for GC, and diagnostic interval were independent risk factors.The predictive efficacy of the prognostic nomogram PeerJ reviewing PDF
Characteristics of Lawyers Portrayed in Television Advertising: The Effects of Preference, Client-Role and Advertisement Type

Field: Social Sciences (Social Sciences)

ABSTRACT This research examines the evaluation of legal television advertisements and the lawyers or law firms represented by these advertisements. Three hypotheses are tested concerning the evaluation of the ads relative to a lawyer's professionalism and personal demeanor, likelihood of choosing a law firm based on a portrayal of desirable characteristics and the varying ability of the ad to attract the consumer depending on whether one is a plaintiff or defendant. Results indicate that ads perceived with more professionalism are evaluated more favorably. Differences in evaluations by potential plaintiffs and defendants were only marginally supported.
The Relation of Left Parasternal Impulse and Right Ventricular Systolic Pressure

Field: Medicine (Health Sciences)

A correlative study of kinetocardiographic and apexcardiographic traces taken at the left sternal border and cardiac catheterization data was conducted on a group of 57 patients with various types of heart disease.Several parameters derived from kinetocardiograms and apexcardiograms were examined for the correlation with right ventricular systolic pressure. However, there observed little correlation between them, and, it appeared difficult to obtain any reliable estimate of the pressure from these parameters. The pressure calculated from the IIp-T interval by using the Burstin's method was moderately correlated with the pressure directly obtained by catheterization. However, this method seemed inadequate for clinical use, because of its unnegligible error and a difficulty involved in the measurement of the IIp-T interval.Nevertheless, kinetocardiograms and apexcardiograms were a useful procedure in detection of right ventricular hypertension and, furthermore, yielded some qualitative information on the level of ventricular pressure. The merit of the kinetocardiogram in this regard was discussed in contrast to the apexcardiogram.
[National strategy in the battle against scorpion stings and envenomations. Application and evaluation].

Field: Health Professions (Health Sciences)

Scorpion stings represent the first cause of poisoning with an incidence of 30 to 50% of all declared cases in the Centre Anti Poison of Morocco (CAPM). Aware of this increasing problem, the CAPM paid special attention to this pathology. Thanks to its retrospective and prospective studies, the scorpion species mapping has been determined as well as the demographic features of stung patients, the nature and the chronology of clinical events in scorpion envenimation, and the epidemiological, clinical and therapeutical factors of severity. On this basis, the CAPM worked out a national strategy to struggle against scorpion stings whose aim was to decrease the morbidity and mortality caused by stings of scorpion as well as to rationalise economic expenses. The components of this strategy were based on the training of the medical and paramedical staff, on information, education, communication involving different sectors, on identification of needs and on follow-up and assessment. A nationwide campaign was implemented to change the population and health-care staff's behaviour regarding this pathology. Its evaluation permitted to improve the compilation of cases with census of 14104 cases, to reduce lethality rate and to rationalise expenses while banishing some medicines and avoiding useless hospitalization.
Household knights, chamber knights and king’s knights: the development of the royal knight in fourteenth-century England

Field: Arts and Humanities (Social Sciences)

The fourteenth century witnessed a considerable change in the way in which knights were retained in royal service in England. The system of retaining ‘household knights’, which had been in operation since at least the twelfth century, gave way to a new system based around the retaining of ‘chamber knights’ and ‘king’s knights’. These new ranks were retained in different ways to the household knights and often performed different functions. Consequently, the place they occupied in fourteenth-century kingship was markedly different. Despite the significance of this development, the scholarship on it has been limited and often contradictory. This article offers a detailed reassessment of how and why this development occurred and what its impacts were for the fourteenth-century polity.
Historical core vocabulary: Spring and/or anchor: On tendencies and mechanisms of language evolution

Field: Arts and Humanities (Social Sciences)

This paper argues that lexis evolution is guided by certain internal impulses generated and stimulated by the processes taking place in its historical core (HCV) comprised by the lexemes dating back to the earliest stages of the language history and characterized by simple morphological structure, stylistic neutrality, polysemy, high derivational potential, and high frequency.1 Diachronic research of the lexes of two cognate languages – English and German – demonstrated that these characteristics not only account for the HCV longevity but also ensure its structural, semantic, and functional centrality, and consequently, evolutionary significance. The study demonstrated that the role the HCV plays in lexis evolution is twofold. On the one hand, the interplay of its inherent characteristics, that ensured its structural and semantic ties with the entire lexis, makes it a stabilizing factor. On the other hand, the same attributes alongside with intense developmental processes in the HCV which are disseminated throughout the system make it a powerful dynamic factor.
THREE-STAGE CLOS-NETWORK SWITCH ARCHITECTURE WITH BUFFERED CENTER STAGE FOR MULTI-CLASS TRAFFIC

Field: Computer Science (Physical Sciences)

Memory-space-memory (MSM) arrangement is a popular architecture to implement three-stage Clos-network switches with distributed arbitration. The scalability of this architecture, however, is limited by the round-trip communication delay between the first and the second stages. Moreover, virtual output queue does not completely remove the blocking in the buffered modules under multi-class traffic. In this paper, we propose a competition-free memory–memory–memory (CFM 3 ) switch which is a three-stage Clos-network switch with buffered center stage. The CFM 3 deploys buffered modules in all stages to simplify communication between stages. To reduce the blocking, each module is equipped with a set of buffers fully separated according to the destinations, classes of packets and the input ports of the module. Despite the buffered center stage, CFM 3 is free from reordering problem due to simple control mechanism. Simulation result shows the delay of the proposed CFM 3 switch closely approaches that of the ideal Output Queued switch under multi-class traffic when strict priority policy popularly used for class-based switch is deployed. The CFM 3 achieves 100% throughput under uniformly distributed four-class traffic with strict priority policy while traditional MSM switch records about 77% throughput.
Evolutionary coupling analysis identifies the impact of disease-associated variants at less-conserved sites

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Genome-wide association studies have discovered a large number of genetic variants in human patients with the disease. Thus, predicting the impact of these variants is important for sorting disease-associated variants (DVs) from neutral variants. Current methods to predict the mutational impacts depend on evolutionary conservation at the mutation site, which is determined using homologous sequences and based on the assumption that variants at well-conserved sites have high impacts. However, many DVs at less-conserved but functionally important sites cannot be predicted by the current methods. Here, we present a method to find DVs at less-conserved sites by predicting the mutational impacts using evolutionary coupling analysis. Functionally important and evolutionarily coupled sites often have compensatory variants on cooperative sites to avoid loss of function. We found that our method identified known intolerant variants in a diverse group of proteins. Furthermore, at less-conserved sites, we identified DVs that were not identified using conservation-based methods. These newly identified DVs were frequently found at protein interaction interfaces, where species-specific mutations often alter interaction specificity. This work presents a means to identify less-conserved DVs and provides insight into the relationship between evolutionarily coupled sites and human DVs.
Evaluation of the anticorrosive painting procedure with reused abrasive for surface preparation – a case study

Field: Engineering (Physical Sciences)

Abstract Atmospheric corrosion is a relevant cause of failure for many metallic structures. Its aggressiveness depends on environmental factors such as relative humidity, salinity, and contaminants. Anti-corrosion paint is the most used technique to minimize this problem, and surface preparation is a fundamental step for suitable paint adhesion. Abrasive blasting can remove oxides and old paint and texture the surface for receiving a new coating. An alternative to reduce costs is reusing abrasive particles to make the process more sustainable. In this investigation, an paint system was qualified through tests in its current environment. The influence of reused abrasives on the painting process by the paint layer’s thickness and its adhesion to the substrate was evaluated. Samples blasted with new and reused abrasives were prepared to evaluate the surface preparation process, allowing surface roughness measurements and incrustation analysis. It was possible to observe that the layers of paint were thin and not uniform, had approximately 155 μm thick, and defects such as pinholes. Reusing the abrasive did not affect the surface average roughness, which was 9.4 ± 2.5 μm. Abrasive incrustation and other contaminants such as Na, P, K, S, and Cl were found on new and reused abrasive surfaces. Recommendations for improvement and suggestions for changing the process were possible to assess.