jimnoneill/paper-to-field-training huggingface dataset:
Investigaton of effects of anoxia and cysteamine on total protein content and levels of protein sulfhydryl groups in myeloid cells of rat bone marrow

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

It was previously demonstrated by the cytophotometric method that in vivo-induced anoxia raises substantially the levels of protein thiols in bone marrow cells, whereas another radioprotective agent, cysteamine, does not have an appreciable effect on protein thiol content of bone marrow cells, but raises the levels thereof in epithelial cells of the small intestinal mucosa and hepatic cells. The objective of this study was to determine whether the thiol-raising effect of these agents is related to changes in protein content or structure.
Penerapan Model Pembelajaran CTL yang diberi Penekanan pada Komponen Inkuiri dalam Pembelajaran Lay-Up Shoot

Field: Social Sciences (Social Sciences)

This CTL learning model was chosen considering the PJOK learning outcomes of students of
class X-IPS 1 of Public High School Negeri 4 Singaraja in the 2019/2020 academic year were
initially still low, reaching an average value of 69. On this basis, this study aimed at improving
the result of achievement in lay-up shoot learning, and students’ response toward the
implementation of CTL teaching model which concerned to the component of Inquiry Method.
The study was designed using two cycles. The data of this were analyzed using descriptive
statistics. The achievement of basic competency completeness rate for lay-up shoot was
converted with competency rate mastery for Physical and Health Education subject applied in
Public High School 4 Singaraja. Based on score accumulation data of psychomotor aspect,
cognitive aspect, and affective aspect acquired in cycle I and II, after being analyzed using
descriptive statistics, it was classically achieved basic competency completeness rate 95% or A
predicate (very good). Therefore, it can be concluded that the implementation of CTL teaching
model which concerned to the component of Inquiry Method was very effective and gained a
positive response as a learning method the achievement of lay-up shoot learning in basketball
game toward the students of class X-IPS 1 Public High School 4 Singaraja in the Academic
Year 2019/2020.
An Image Processing Based Controller for a Three Degrees of Freedom Robotic Arm

Field: Engineering (Physical Sciences)

This paper presents the image processing based control approach for an industrial arm. Firstly, the dynamics of 3-DOF robot arm is developed. Then, a controller combined with image processing method on Matlab software is proposed. Finally, the robot arm is designed by using the Solidwork tool, which then is embedded in Matlab software to simulate the closed-loop system. The simulation results show that the robot arms work more reliably and accurately. From this result, the controller can be applied on an industrial robot arm to serve in industrial and agricultural production with high intelligence.
Ultrafast optical manipulation of ferromagnetic order in InMnAs/GaSb

Field: Physics and Astronomy (Physical Sciences)

We have performed a two-color time-resolved magneto-optical Kerr effect (MOKE) study of a ferromagnetic InMnAs/GaSb heterostructure. We observed ultrafast photo-induced changes in the MOKE signal induced by a large density of spin-polarized transient carriers created only within the InMnAs layer using intense 140 fs mid-infrared pulses. Our data clearly demonstrates that magnetic properties, e.g., remanence and coercivity, can be strongly modified. The dependence of these changes on the time delay, pump polarization, pump intensity, and sample temperature is discussed.
The use of various materials and drugs for the prevention of the development of postoperative lumbar epidural fibrosis: literature review

Field: Medicine (Health Sciences)

The paper is a review of the current literature data on the use of various materials and drugs for the prevention of the development of postoperative lumbar epidural fibrosis. Literature searches were performed in the Pubmed, Medline, EMBASE, Cochrane Library and eLibrary databases. The formation and growth of fibrous tissue in the epidural space, followed by tissue adhesion to the dura mater, is the leading cause of pain afferentation in the lumbar spine and/or lower extremities. Several molecular and cellular mechanisms play an important role in the pathophysiology of connective tissue formation in the epidural space. An analysis of experimental and clinical studies examining the effectiveness of various materials and drugs is presented. The authors present the current data on new therapeutic approaches to the prevention of postoperative epidural fibrosis. Topical, unresolved issues which necessitate further research on the pathophysiology of epidural fibrosis are indicated.
Reprogramming cells and their use in regenerative therapy (19.2)

Field: Medicine (Health Sciences)

The growth of the coronary collateral circulation has a beneficial effect on the consequences of ischemic heart disease. Despite this importance, strategies to develop coronary collaterals have not been successful. For example, administration of growth factors has not been successful in stimulating the growth of coronary collaterals in patients. Because of these shortcomings, we adopted new strategies to stimulate coronary collateral vessels using genetically reprogrammed cells. We reprogrammed endothelial cells into a progenitor‐like cell that remains committed to a vascular differentiation program and can become either smooth muscle or endothelium (termed induced vascular progenitor cells [iVPCs]). Administration of iVPCs stimulated the growth of collateral vessels in the heart. Other types of stem cells (mesenchymal stem cells, cardiac stem cells) or native endothelial cells did not have the same stimulatory effect on coronary collateral growth. Although the mechanisms by which iVPCs stimulate collateral growth have not been unequivocally defined, these cells incorporate and engraft in growing blood vessels in the heart. Although the benefit of using reprogrammed cells to stimulate vascular growth in the heart in models of vascular disease is not yet defined, the use of certain types of reprogrammed cells may offer a substantial advance in the treatment of ischemic heart disease.
“The Inner Frontier”. Borders, Narratives, and Cultural Intimacy in Topolò/Topolove

Field: Social Sciences (Social Sciences)

On 21 December 2007 one of the most contentious borders in Europe, the one between Slovenia and northeastern Italy, finally opened. This article presents narratives from the village of Topolò, near the Italian–Slovenian border, by three generations that lived with the border in different ways. Some people developed strategies to bypass it, whereas others built up a contrasting ethnicity and an “inner frontier” that emotionally shapes their lives. *** 21. decembra 2007 je bila naposled odprta ena spornejših mej v Evropi, tista med Slovenijo in severovzhodno Italijo. Članek predstavlja pripovedi treh rodov iz vasi Topolò/ Topolove ob italijansko-slovenski meji. Ti so z mejo živeli na različne načine: nekateri so razvili strategije, da so jo obšli, drugi so si ustvarili nasprotno etničnost in “notranjo mejo”, ki čustveno oblikuje njihova življenja.
<title>Development and introduction of a knowledge-based system for mechanical engineering</title>

Field: Computer Science (Physical Sciences)

The system is designed for the configuration of industrial mixing-machines is assist members of the sales department. The process of configuration is split in two parts. In the process- engineering part, the mixing-machine is characterized by the kind of agitator and the number of revolutions in respect to the mixing task. In the second part, all components of the mixing- machine are determined with regard to the laws of mechanics. Different kinds of knowledge had to be implemented. Structural knowledge is represented by objects whereas algorithmic knowledge is coded in functions. Directed constraints are used to express causal dependencies. Technical parameters and available parts are stored in databases. These databases also serve as an interface to the existing CIM-system. The database-format chosen allows an easy maintenance of the data by various tools. The process of configuration is characterized by loops of feedback. Often parameters are needed before they can be computed, therefore they have to be pre-estimated. Later on they are checked and probably re-computed. Main decisions in the process of configuration are done by the user. The system supports the user by suggesting the cheapest components. The development of the system and the need for explanation of the expert knowledge has had an interesting side-effect: the revision of various methods and standards of the manufacturer. It turned out, that there are two different kinds of validation: the validation of process-engineerical and mechanical knowledge done by the experts and the usefulness for daily work examined by members of the sales department.
Smart logistics in the evolution of the logistics

Field: Business, Management and Accounting (Social Sciences)

The aim of the article is to try to define the scope of the meaning of the concept of smart logistics as well as to determine the place in the evolution of the logistics. The definitions available in the literature were analyzed and the author's definition was proposed. The attributes of the smart logistics concept are indicated. The stages of logistics concept evolution were tracked and shown how of smart logistics concept determines the contemporary management of supply chains. The Internet of Things was discussed as a determinant of the development of intelligent logistics.
Research on Machine Vision in Forestry Pluck System

Field: Computer Science (Physical Sciences)

Forestry industry is an important part of nation's economy. In this paper, a machine vision system is presented as a key module of Camellia oleifera pluck robot. In order to cut fruit image up from complicate background, SOFM neural network and gray thresh is used in image segmentation. In SOFM method, take R-B,G-R,G-B and hue H tunnel as input feature vectors, use self-organization network to clustering can get the best effect. in gray threshold method can take various of method to get the best threshold, such as PSO and GA algorithm, and MATLAB includes the toolboxes. At last use noise ratio, area ratio, divided time, Fourier boundary descriptors and other indicators to assess the accuracy of segmentation. The methods have the significance to the current and subsequent research of forestry pluck device.
Biosynthesis of Bi-, Tri-, and Tetraantennary Oligosaccharides Containing α-D-Galactosyl Residues at Their Nonreducing Termini

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The ability of Ehrlich tumor cell alpha(1,3)-galactosyltransferase to catalyze the incorporation of alpha-D-Gal residues into a specific branch of bi-, tri-, and tetraantennary oligosaccharides has been investigated by acetolysis followed by gel filtration of the fragments on Bio-Gel P-4. Taking advantage of the carbohydrate specificity of the Griffonia simplicifolia I-B4 isolectin, the mono-[14C]alpha-D-Gal derivatives were isolated by affinity chromatography. Analysis of the acetolysis fragments generated by cleavage of the multiantennary substrates indicates that the Ehrlich cell alpha(1,3)-galactosyltransferase acts preferentially on the alpha-D-Man(1,6) arm. This branch is preferred 2.5 times in bi-, 5.6-8.5 times in tri-, and 12.7 times in tetraantennary structures over the alpha-D-Man(1,3) arm. Within the alpha-D-Man(1,6) branch, in turn, there is a 1.3-1.9-fold consistently higher frequency of galactosylation of the beta-D-GlcNAc(1,2) as compared to the beta-D-GlcNAc(1,6) antenna.
Implementation of Life Cycle Costing in Enhancing Value for Money of Projects

Field: Decision Sciences (Social Sciences)

Life Cycle Costing (LCC) is becoming more important since long-term building owners and clients have begun to demand an estimate evidence of what their cost of ownership will accrue to.LCC is a sophisticated approach to estimating the cost incurred in the future and produce comprehensive costing information. Despite growing awareness of LCC practices and concepts among practitioners, actual implementation of this technique is slow to take hold, especially in the Malaysian construction industry. The concept of LCC seems poorly understood; thus, there is a need to overcome this deficiency in order to successfully deliver LCC in the construction industry. This paper aims to study the implementation of LCC, with the main focus on the design stage towards enhancing overall value for money. The relationships between the factors of LCC implementation that can contribute to projectâ€Ÿs value were investigated. The results of this study revealed several critical factors of LCC that should be taken into account to raise awareness and promote LCC implementation at the design stage among the construction practitioners. The challenges to implementation are also discussed in this study.
Survey of Phaeomoniella chlamydospora in vineyard weeds

Field: Agricultural and Biological Sciences (Life Sciences)

ABSTRACT Petri disease is serious, complex and difficult to control in vines worldwide. The main causal agent of this disease is the fungus Phaeomoniella chlamydospora. This fungus also occurs in the vineyard weed Convolvulus arvensis. In Brazil, this fungus was found only in grapevines. Thus, the aim of the present study was to carry out a phytosociological survey of weeds in an area with different vine rootstocks, as well as in a field of seedlings production, in an experimental area with vines and in different areas with commercial vineyards, besides verifying which weed species could be hosting the fungus P. chlamydospora. For the phytosociological survey of weeds, a square was randomly cast ten times at the site, followed by counting, identification and sampling of all species. To verify host species of the fungus, vascular tissue of plants was isolated in culture media and DNA extraction from the same plant tissue was carried out followed by PCR with specific primers of the fungus for the elongation factor gene (Pchlamy-EF-F 5’-CTCATTATCACATTTTGCTGC-3’ and Pchlamy-EF-R 5’-GAGAACAGTCAGTGATGAGC-3’). Considering all surveyed fields, 46 weed species were detected in 17 families, especially Asteraceae and Poaceae, which had the largest number of species. Using conventional or molecular methods, the fungus P. chlamydospora was not detected infecting weeds, which highlights that Petri disease occurs only in grapevines.
Study of correlative factors affecting curative effect and prognosis of sudden sensorineural hearing loss

Field: Medicine (Health Sciences)

OBJECTIVE To analyze correlative factors which affect curative effect and prognosis of sudden sensorineural hearing loss.METHODS 113 cases of sudden sensorineural hearing loss(114 ears)who had whole medical records hospitalized in our department were collected,retrospective analysis were made.Stata 12.0 software were used to calculate the data.We treated curative effect as binary outcome variable and ordinal outcome variable respectively,sex,age,hearing graph,initial time of treatment,auditory threshold,hormone therapy or not,and accompanied by microcirculatory disturbance complication or not,tinnitus,vertigo,otopathy or not were considered as independent variables,and we analyzed relationship with prognosis by full-factor model and gradual Logistic regression analysis.RESULTS The effective rate of hormone therapy team was 75.9%,though non-hormone therapy team was 57.6%.Auditory threshold is the unique factor that influences curative effect by Logistic regression analysis of multiple factor.CONCLUSION Lower auditory threshold a sudden sensorineural hearing loss patient has,better curative effect he will get.
Immune checkpoint inhibitor-related gastrointestinal adverse events: a disproportionality analysis based on the FAERS database

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but are frequently linked to gastrointestinal immune-related adverse events, which can severely affect patient outcomes. We conducted a retrospective pharmacovigilance study using the FDA Adverse Event Reporting System (2011–2024). Disproportionality analyses (ROR, PRR, BCPNN, MGPS) identified gastrointestinal adverse events (AEs) associated with ICIs across pan-cancer populations, while multivariable logistic regression and Bayesian network modeling were used to examine influencing factors. A total of 85 distinct gastrointestinal toxicities were identified and categorized as ICI-related gastrointestinal AEs (GI AEs). Substantial variation in ICI-related GI AE profiles was observed across different ICI regimens, with anti-CTLA-4 demonstrating the highest toxicity (ROR = 17.76 [16.88–18.68]). Logistic regression and Bayesian network analyses indicated that disease stage, concurrent targeted therapies, and ICI type significantly influenced the risk of developing ICI-related GI AEs. Patients with gastric variceal hemorrhage exhibited the highest mortality rate (63.64%). Our pharmacovigilance analysis reveals a high risk of gastrointestinal adverse events with ICI therapy, especially anti-CTLA-4. Stage IV disease, concurrent targeted therapies, and anti-CTLA-4 therapy or combination therapy further increase this risk, highlighting the need for personalized treatment strategies.
Commercial sex and the single girl: Women's empowerment through economic development in Thailand

Field: Social Sciences (Social Sciences)

The author presents the views of Thailand's Population and Community Development Association (PDA - Thailand's largest NGO) about how to provide women attracted to the commercial sex industry (CSI) with economically viable alternatives to this accepted (in Thailand) type of `manual labour'. Research has shown that poverty is the major factor cited by voluntary commercial sex workers (CSWs) as influencing their move into the industry, and that economic development is their way out.
Investigations on the Storage Behaviour of Roundwood from Healthy and Diseased Beeches

Field: Agricultural and Biological Sciences (Life Sciences)

Healthy and variously diseased beeches were felled in March 1985 and were stored, with bark, on supports during the summer months in order to study any effects of disease on storage behaviour. By repeatedly taking disks from stored logs, visible storage defects were registered, moisture content of the wood was determined, and the wood inhabiting microflora was studied by systematic isolation from the wood. Two to three months after felling insignificant brown stained zones appeared in the uppermost sapwood and some minute brown specks were distributed over the entire cross section, which tended to spread over large areas during the storage period. Finally, white rot fungi occasionally destroyed smaller or larger zones between the discoloured brown ones, in initially healthy beeches just as much as in damaged ones. W ood staining microorganisms can only partly be made responsible for these considerable discolorations. Although blue staining fungi had occupied an important position in all logs under study, fungal hyphae were only rareIy found in the dark brown zones even in advanced stages. Here only a profuse formation of tyloses and an increase as weil as oxydative dark staining of the parenchyma cell contents was noticed.
[Therapy of Wilson disease].

Field: Medicine (Health Sciences)

Wilson disease is a copper storage disease with autosomal-recessive trait that is predominantly a disorder of the adolescent and young adult. Clinical manifestations are dominated by hepatic and/or neurological symptoms. Diagnostic procedures include determination of total serum copper, free serum copper and serum ceruloplamin concentrations as well as urinary copper excretion. Confirmation of diagnosis may be achieved by liver biopsy and histological determination of copper content. The aim of treatment is reduction of tissue copper concentration and detoxification of copper. Drugs applied are the chelating agents. D-penicillamine and trientine, or zinc. The chelating agents induce renal and biliary copper excretion and increased synthesis of metallothionein, which attaches and detoxifies intracellular copper, leading to impaired absorption and binding of excess intracellular copper. Treatment with zinc results in induction of hepatic and intestinal metallothionein synthesis. Regular examinations of the parameters of copper metabolism are necessary in order to control the therapeutic effect. Free copper serum concentrations and urinary copper excretion should reach values below 10 micrograms/dl and 80 micrograms/day, respectively. A significant improvement of clinical symptoms and normalization of parameters of copper metabolism can be expected earliest six months after onset of therapy. Anti-copper treatment may be accompanied by copper-reduced diet. Lifelong therapy is required and provides life-expectancy near to normal. Interruption of treatment leads to reaccumulation of copper, often resulting in fulminant hepatic failure. This can also be observed as initial presentation in 5% of cases (predominant age 12 to 25 years). End stage liver disease and fulminant hepatic failure are indications for liver transplantation by which the genetic defect is phenotypically cured. Here decoppering treatment is no longer required. Whether severe neurological disorders may also be improved is not clear until today.
Alaska: Are We the Waiting?

Field: Economics, Econometrics and Finance (Social Sciences)

In the wake of 2014’s global collapse in oil prices, Alaska continues to struggle with a hugedeficit. Fortunately, the state has over $60 billion in savings to finance its fiscal gap, but Alaskanscontinue to fight over the need for spending cuts and new taxes. Outside of state governmentrevenue, Alaska’s economy remains relatively unaffected by low oil prices, and the state’sreserve funds are growing. So far, though, Alaska’s legislature has not generated a coherent solutionto the state’s unbalanced budget for the long term.
An Extended Single-Valued Neutrosophic Projection-Based Qualitative Flexible Multi-Criteria Decision-Making Method

Field: Decision Sciences (Social Sciences)

With respect to multi-criteria decision-making (MCDM) problems in which the criteria denote the form of single-valued neutrosophic sets (SVNSs), and the weight information is also fully unknown, a novel MCDM method based on qualitative flexible multiple criteria (QUALIFLEX) is developed. Firstly, the improved cosine measure of the included angle between two SVNSs is defined. Then, the improved single-valued neutrosophic projection is developed, and the corresponding improved single-valued neutrosophic bidirectional projection and single-valued neutrosophic bidirectional projection difference are investigated. Moreover, the partial ordering relation of SVNSs is developed. Secondly, an extended QUALIFLEX method based on an improved single-valued neutrosophic projection measure is proposed to handle MCDM problems in which the weights of criteria are completely unknown. Finally, an example for selection of a green supplier, as well as a performance comparison analysis, are provided to demonstrate the effectiveness of the proposed method.