jimnoneill/paper-to-field-training huggingface dataset:
An examination of the constraints to teaching and learning outdoors in public elementary and high schools in Winnipeg, Manitoba

Field: Social Sciences (Social Sciences)

Alternating traditional classroom-based teaching techniques with hands-on learning activities outdoors is beneficial for children of all ages. The purpose of this thesis was to explore whether and how teachers may negotiate the constraints to facilitating hands-on learning opportunities outdoors. A snowball sample was used to identify twelve outdoor educators for semi-structured interviews documenting their characteristics, skills and experiences, perceptions of the constraints to outdoor education and recommendations for building interest in and supporting outdoor education. The findings suggested that participants’ childhood experiences outdoors were influential on their decisions to start teaching outdoor education, and that the participants’ perceptions of the constraints varied dependent on their experiences, objectives and attitudes. The participants’ recommendations were focused on what teachers could do to help themselves and each other to succeed. Altogether, the participants’ experiences suggest that passionate and engaged outdoor educators can have a lasting impact on students’ relationships with the natural world.
Management of psoriasis in childhood

Field: Medicine (Health Sciences)

It is not unusual for psoriasis to start in childhood although a mild or atypical presentation sometimes makes it difficult to establish a confident diagnosis at this age. All adult forms occur but flexural psoriasis and guttate psoriasis are particularly common. Management involves education of the child and parents concerning the nature of psoriasis and the effects of treatment. Genetic counselling may be provided if needed based on population data. Environmental triggers of psoriasis should be sought particularly infection. Psoriasis can usually be treated effectively in children with topical agents including emollients, coal tar, corticosteroids, dithranol and calcipotriol according to age and the sites affected. In those who do not respond, consideration should be given first to day care or in-patient treatment which may be combined with UVB phototherapy. Systemic therapy should be used only under extreme circumstances such as resistant erythrodermic, pustular or arthropathic psoriasis. There are no controlled trials in this age group but the most experience has been with retinoids which are probably the second-line drug of choice for children. Methotrexate and cyclosporin appear to be effective in children but more efficacy and safety data are required.
Identification of Histamine Metabolite 1-methyl,4-imidazole Acetic Acid in Human Urine and its Absence in Status Asthmaticus

Field: Medicine (Health Sciences)

Lincomycin and Pristinamycin-Barber and Waterworth MEDICATJISHRNAL In spite of chemical differences, lincomycin has been shown to have an antibacterial activity similar to that of the macrolides, including partial cross-resistance.Pristinamycin has an activity that might have been predictedfrom its chemical similarity to ostreogrycin.
Comparison of Gastric Inflammation in Balb/c Inoculated by Three Unique EPIYT Motif CagA Gene Helicobacter pylori Bali Isolates Based on Update Sidney System Criteria

Field: Medicine (Health Sciences)

Introduction Helicobacter pylori infection (H. pylori) is associated with gastrointestinal diseases including gastritis, peptic ulcer, gastric carcinoma and gastric mucosa-associated lymphoid-tissue lymphoma (MALT Lymphoma). H. pylori bacteria have been classified into class 1 carcinogen in human
Cardioprotective effects of mioflazine during 1 h normothermic global ischaemia in the canine heart

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The cardioprotective effects of mioflazine, a recently developed cardiovascular drug, were investigated in 41 anaesthetised open chest Beagle dogs subjected to 1 h normothermic global myocardial ischaemia. The severity of the model is evidenced by the finding that only one out of 20 control dogs could be weaned from extracorporeal bypass. Oral pretreatment with mioflazine (2.5 mg X kg-1) resulted in complete functional recovery in 17 out of 20 animals. Biochemical analysis of left ventricular biopsies taken before, during and after aortic cross clamping showed a preservation of purines and a better recovery of ATP, ATP/ADP X Pi ratio and energy charge (p less than 0.05) in the pretreated animals. Morphological and cytochemical assessment of the myocardium demonstrated that the ultrastructure of the sarcolemma and its calcium binding capacity is remarkably well preserved in the drug treated animals. These results indicate a strong cardioprotective effect of mioflazine. The biochemical, cytochemical and ultrastructural findings suggest an interaction of the drug with the sarcolemma.
Passing Grace and Seized Microphones (1967–1969)

Field: Social Sciences (Social Sciences)

Abstract In response to the racial unrest that erupted across the United States in the summer of 1967, presiding bishop John E. Hines persuaded Episcopalians to adopt what became known as the General Convention Special Program (GCSP). This program sought to confront the pervasive inequalities of American life by providing empowerment grants to minority community groups with “no strings attached.” The program’s administration soon alienated black clergy, though, and it failed to inspire the white congregations upon which it depended. The gulf between the church’s liberal leadership and more traditionalist laity continued to widen during these years, further exacerbated by the number of clergy speaking out against the Vietnam War. Matters came to a head at the Special General Convention in September 1969, when proponents of the Black Manifesto demanded the Episcopalians pay reparations for slavery. Unhappy and divided, the Episcopal Church struggled with a loss of members, money, and focus.
The frequency of reassortment in vivo is dependent on inoculum dose<sup>1</sup>.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

1<p>The difference in % reassortants between 10<sup>3</sup> and 10<sup>6</sup> groups was found to be significant, with p = 0.03 (Student's T-test).</p>2<p>n was 30 for 1, 2, 3, 6, 7, and 8; n was 25 for 4 and 5; n was 26 for 9 and 10.</p>3<p>n ranged from 19 to 24.</p>
Digital Twins of Mechanically Ventilated Preterm Neonates with Respiratory Distress Syndrome

Field: Medicine (Health Sciences)

Background: Mechanical ventilation is life-saving for preterm infants with respiratory distress syndrome but can also contribute to lung injury and long-term morbidity. Protective ventilation strategies are recommended, yet implementation in neonatal intensive care units remains inconsistent, and infants continue to be exposed to injurious ventilator settings. Objective: To develop and validate a cohort of neonatal digital twins, based on mechanistic models of cardiopulmonary physiology calibrated to individual patient data, as a tool for simulating and optimising protective ventilation strategies. Methods: A high-fidelity computational simulator of human cardiopulmonary physiology was adapted to neonatal-specific parameters, including lung compliance, dead space, pulmonary vascular resistance, oxygen consumption, and fetal haemoglobin oxygen affinity. Digital twins were generated using data at 65 time points from 11 preterm neonates receiving volume-controlled ventilation. Model parameters were calibrated to minimise the error between simulated and observed PaO2, PaCO2, and peak inspiratory pressure (PIP). Results: Digital twins reproduced measured data with mean absolute percentage errors of 3.9% (PaO2), 3.0% (PaCO2), and 5.8% (PIP) across the cohort. Predictions for uncalibrated variables (pHa, SaO2, mean and minimum airway pressure) also showed high accuracy, with errors <5%. Strong correlations and narrow limits of agreement were observed across all patients and time points. Conclusions: This study demonstrates, for the first time, the feasibility of creating fully mechanistic digital twins of mechanically ventilated neonates with RDS. The twins accurately captured patient-specific gas exchange and respiratory mechanics, supporting their potential as a platform for conducting virtual clinical trials and for the design of individualized, lung-protective ventilation strategies.
Cicer arietinum L. IG 155127

Field: Agricultural and Biological Sciences (Life Sciences)

Plant Genetic Resource.
Taxonomy: Cicer arietinum L.
Common name(s): Chickpea
Conserved by: International Centre for Agricultural Research in Dry Areas (ICARDA), Lebanon
Local sample unique identifier: IG 155127
Method of creation: Acquisition
Date: 2012-08
Other identifiers: n/a,ILC 0
Historical: No
Biological status: Other
MLS status: Included
ANTECEDENTS OF CUSTOMER TRUST AND LOYALTY ON SHOPEE INDONESIA

Field: Business, Management and Accounting (Social Sciences)

Lack of face-to-face interaction, network and software issues, and inability to touch the product become one of E-commerce constraint. Additionally with the widespread news about unsafe transaction and leak of user’s personal data on e-commerce, lead to decreasing of customer trust toward e-commerce. The decrease of customer trust could impact customer loyalty, if this problem does not resolve. This research is to investigate factors that affect customer trust and loyalty on Shopee among generation Z in context of fashion category, utilizing technology Acceptance Model (TAM). Since Shopee is the top e-commerce with annual growth, while generation Z dominating the e-commerce. Additionally, fashion category is the most category that produce the biggest revenue. Data collected using a survey within 400 respondents that fulfil the requirements. Utilizing descriptive analysis and PLS-SEM, to find whether Perceive Ease of Use (PEoU), Perceive Security (PS), Privacy Concern (PC), Product Variety (PV), and On-Time Delivery (OD) affect Customer Trust (CT), while measuring how Customer Loyalty (CL) affected by Product Variety (PV), On-time Delivery (OD), and Customer Trust (CT). The results indicate that CT relies on PEoU, PS, PC, PV, and OD. While PV, OD, and CT significantly impact CL on Shopee especially generation Z. This research provides e-commerce with insights on which factor influence CT and CL the most. Furthermore, this research aims to contribute to the literature regarding antecedents of trust and customer loyalty in Shopee.
The Communication Mix in Pharmaceutical Marketing

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The development of effective communication Mix in Pharmaceutical marketing is a complex task, which goes through identifying the target audience, determining the communication objectives, designing a message, choosing method of delivery, collecting feedback. Pharmaceutical marketing professionals are fast becoming aware of the latest development in the discipline of marketing, and they have also started to adopt latest theories in communications. Unlike a few years back, when all tools were used in isolation from each other, which messages and format changing as per the requirement of the tool, now we find a synergy in all marketing activities. Marketers are making all efforts to make sure that each next step in the communication process adds some value to the previous one. Product slogans, logos and positioning statements are taking up fast. In-Clinic Promotional/Communication Mix includes detailing aid; leave behind material, samples, gift/giveaways, and direct mailers. Out-of-Clinic Promotional/Communication Mix includes clinical trials/studies, seminars/symposia/round table discussion sponsorships, film shows, advertisements, public relations, free medical camps, corporate marketing, hospital/ward improvement programs, E-marketing. The prescription chain starts with the information to the doctor by the company’s sales team. The information is communicated through either in-clinic promotional activities, or out-of-clinic promotional efforts. The doctor, if convinced, prescribes the product and the patient goes and buys the product, thus making the both Product Chain & Prescription Chain meet in the end, which was the basic marketing objective.
Loop-Mediated Isothermal Amplification Assay to Detect Invasive Malaria Vector Anopheles stephensi Mosquitoes

Field: Immunology and Microbiology (Life Sciences)

Spread of the Anopheles stephensi mosquito, an invasive malaria vector, threatens to put an additional 126 million persons per year in Africa at risk for malaria. To accelerate the early detection and rapid response to this mosquito species, confirming its presence and geographic extent is critical. However, existing molecular species assays require specialized laboratory equipment, interpretation, and sequencing confirmation. We developed and optimized a colorimetric rapid loop-mediated isothermal amplification assay for molecular An. stephensi species identification. The assay requires only a heat source and reagents and can be used with or without DNA extraction, resulting in positive color change in 30-35 minutes. We validated the assay against existing PCR techniques and found 100% specificity and analytical sensitivity down to 0.0003 ng of genomic DNA. The assay can successfully amplify single mosquito legs. Initial testing on samples from Marsabit, Kenya, illustrate its potential as an early vector detection and malaria mitigation tool.
Comparison between the efficiency of pharmacotherapy and cognitive behavioral therapy in reducing captagon (fenethylline) dependence and relapse prevention

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Aims To examine the therapeutic efficacy and effectiveness of cognitive behavior therapy and pharmacotherapy in the treatment of Major Captagon (Fenethylline) Dependence. Method A 41 outpatients males selected for the study, diagnosed as they are suffering from Captagon Dependence according to the DSM-5, with mean age 34.58 ± 5.11. The sample was divided into three experimental groups, (A) (N = 14) treated by cognitive behavior therapy (CBT) and pharmacotherapy in combination. (B) (N = 13) treated by CBT alone. (C) (N = 14) treated by pharmacotherapy alone. All groups were assigned to four measurements, one for the baseline before any treatment interventions, one post-treatment evaluation and two for follow-up within a short and long time. Non-parametric statistics were used to analyze the data collected by SPSS. Result There is no significant intra-group differences were found in terms of baseline assessment. There was no significant discrepancy between the first and the second group except in the term of reducing Captagon craving, as it was clearer in the first group in comparison with other groups. There was a clear significant discrepancy between the first and third groups, for all the study variables and it is phases of assessment especially follow-up. There was a clear degree of differences among the second and the third group, through the different phases of post-assessment, which refers to the great efficacy and effectiveness of CBT in Treating Captagon Dependence CBT was proved to be more effective than pharmacotherapy in the treatment of Captagon Dependence. The combination of CBT and pharmacotherapy was more effective than each other alone in the treatment of Captagon Dependence and Relapse Prevention. Conclusion Available evidence suggests that cognitive–behavioral therapy is an effective intervention method for psychological aspects of automatic thoughts, depression, negative health beliefs, craving, and relapse prevention, although its efficacy in reducing Captagon (Fenethylline) dependence.
Science Fiction in Chile

Field: Arts and Humanities (Social Sciences)

Chile could not lay claim to any indigenous SF until 1959. That year, however, marked the first appearance in print of Hugo Correa, who remains the most prolific as well as the best writer of SF that Chile has so far produced. Los Altissimos (The Superiors, 1959), his first book (of five, to date) is something of a classic, certainly an auspicious beginning to a “Golden Age” of Chilean SF. Second to Correa is Antonio Montero Abt, with three SF titles to his credit—most notably, Acá del tiempo (This Side of Time, 1969). But Montero apparently ceased writing after 1970, and no one else of talent among bis compatriots has since devoted her or himself to writing SF exclusively and in quantity. There is, perhaps predictably, one renowned “mainstream” author, Miguel Arteche, who momentarily condescended to an S-F future history, El Cristo hueco (The Empty Christ, 1969). And among the SF books of the ’60s, those of Armando Mcnedin, Elena Aldunate Bezanilla, and Ilda Cádiz Ávila deserve mention, even though they have written little and that little entirely in the form of short fictions. So, too, among ‘70s’ writers, Carlos Ruiz-Tagle and Jose Bohr can be singled out, especially the latter for his Manana hacia el ayer (Tomorrow Towards Yesterday, 1975). And finally, just for the record, there also exist some execrable SF stories by Roberto von Bennewitz and Rene Peri Fagerstrom. Chile’s “Golden Age“ has proved to be short-lived: it lasted until about the time of Allende’s overthrow—until 1975, to be precise—since which time SF activity in the country has virtually come to a complete halt. (RMP)
Dissection and 2-Photon Imaging of Peripheral Lymph Nodes in Mice

Field: Immunology and Microbiology (Life Sciences)

Two-photon imaging has revealed an elegant choreography of motility and cellular interactions within the lymph node under basal conditions and at the initiation of an immune response (1). Here, we present methods for adoptive transfer of labeled T cells, isolation of lymph nodes, and imaging motility of CD4+ T cells in the explanted lymph node as first described in 2002 (2). Two-photon imaging of immune cells requires that the cells are fluorescently labeled, either by staining with a cell tracker dye or by expressing a fluorescent protein. We demonstrate the adoptive transfer procedure of injecting cells derived from donor mice into the tail vein of a recipient animal, where they home to lymphoid organs within approximately 15-30 min. We illustrate the isolation of a lymph node and describe methods to ensure proper mounting of the excised lymph node. Other considerations such as proper oxygenation of perfused media, temperature, and laser power are discussed. Finally, we present 3D video images of naive CD4+ T cells exhibiting steady state motility at 37°C.
Generating High-Granularity COVID-19 Territorial Early Alerts Using Emergency Medical Services and Machine Learning

Field: Computer Science (Physical Sciences)

The pandemic of COVID-19 has posed unprecedented threats to healthcare systems worldwide. Great efforts were spent to fight the emergency, with the widespread use of cutting-edge technologies, especially big data analytics and AI. In this context, the present study proposes a novel combination of geographical filtering and machine learning (ML) for the development and optimization of a COVID-19 early alert system based on Emergency Medical Services (EMS) data, for the anticipated identification of outbreaks with very high granularity, up to single municipalities. The model, implemented for the region of Lombardy, Italy, showed robust performance, with an overall 80% accuracy in identifying the active spread of the disease. The further post-processing of the output was implemented to classify the territory into five risk classes, resulting in effectively anticipating the demand for interventions by EMS. This model shows state-of-art potentiality for future applications in the early detection of the burden of the impact of COVID-19, or other similar epidemics, on the healthcare system.
THE URGENT TRANSFORMATION OF THE DISCIPLINE OF COMMERCIAL LAW DURING COVID-19 LOCKDOWN

Field: Business, Management and Accounting (Social Sciences)

Appears in: EDULEARN21 Proceedings Publication year: 2021Pages: 8031-8037ISBN: 978-84-09-31267-2ISSN: 2340-1117doi: 10.21125/edulearn.2021.1631Conference name: 13th International Conference on Education and New Learning TechnologiesDates: 5-6 July, 2021Location: Online Conference
Skeletal Actin mRNA Increases in the Human Heart during Ontogenic Development and Is the Major Isoform of Control and Failing Adult Hearts

Field: Medicine (Health Sciences)

Expression of the two sarcomeric actins, a-skeletal and a-car-diac, is regulated in the rodent heart in response to developmen-tal, hormonal, and hemodynamic stimuli. Little is known in man, except that both isogenes were found to be coexpressed in
SPECIFIC FEATURES OF AXIAL SKELETON INVOLVEMENT IN EARLY PSORIATIC ARTHRITIS (The REMARCA TRIAL)

Field: Medicine (Health Sciences)

Objective: to optimize the diagnosis of spinal column involvement in early psoriatic arthritis (ePsA).Subjects and methods. 40 ePsA patients (17 men and 23 women) fulfilling the respective CASPAR criteria were examined. Their median age was 36.5 [28.5; 49.5] years; median PsA duration – 13.5 [5; 24] months. The activity of ePsA was assessed using DAS and DAS28. Presence of inflammatory back pain (IBP) according to ASAS criteria and HLA-B27 was evaluated in all the patients; 38 of them underwent pelvic X-ray to reveal significant sacroiliitis (SSI) (Stage II bilateral or Stage III–IV unilateral SSI) and 37 had magnetic resonance imaging (MRI) of sacroiliac joints. A radiologist determined blindly the presence of active sacroiliits (ASI) as bone marrow edema/osteitis.Results and discussion. In ePsA, median DAS and DAS28 were 3.99 [2.99; 4.92] and 4.22 [3.37; 4.8], respectively. IBP was detected in 22 (55%) patients; it was prolonged in 12 (54.5%); IBP episodes were noted in 10 (45.5%). MRI revealed ASI n 15 (40.5%) of the 37 patients; SSI in 11 (28.9%); 17 (42.5%) patients were HLA-B27 positive. In ePsA, there was a very high association of ASI and SSI with IBP (Q = 0.91, р&lt;0.002 and Q=0.83, р&lt;0.002). No significant relationship was found between ASI and HLA-B27. There was no correlation between ASI and DAS (Q=0.06, р&gt;0.9) and SSI and DAS (Q=0.42, р&gt;0.3). A significant association was revealed between ASI and SSI (Q=0.67, р&lt;0.002). Conclusion. In ePsA, ASI and SSI are identified in 40.5 and 28.9% of cases, respectively. ASI and SSI are closely related to IBP rather than to HLA-B27. The activity of peripheral arthritis does not affect the rate of ASI detected on MRI and SSI in patients with ePsA.
The Inter-Bank Bond Market

Field: Economics, Econometrics and Finance (Social Sciences)

The considerable growth of domestic bond market, attributed to the anticipated macro-economic stability, very broad fund coverage and an obvious increase in institutional bonds. Policy changes also played a very significant role: first, from March 17 the People's Bank of China began to lower the interest rate on excess-reserve deposits. Second, a pilot project enabling the commercial banks to set up their fund-management companies was launched; on July 21, the reform of the exchange-rate regime began; and, the reform of the share-splitting structure opened the way for a huge amount of stock-market funds to enter the bond market. To describe China's financial markets, China's financial system is segregated into different markets governed by different regulating authorities; the inter-bank bond market is one of those markets. In 2005, the volume of bonds issued underwent a huge expansion and a large variety of new bond products entered the market. New players, including the international issue institutions, began to enter the inter-bank market. Influenced by the market environment and policy factors, the interest rates of bond issues fell continuously, while the average issuing term was extended to some degree.