jimnoneill/paper-to-field-training huggingface dataset:
PERAN SELF COMPASSION DALAM MEMEDIASI HUBUNGAN ANTARA FEAR OF FAILURE DENGAN STUDENT ENGAGEMENT

Field: Psychology (Social Sciences)

Student engagement involves student responsibility in the lecture process which can be influenced by fear of failure, in this relationship there is self-compassion that can bridge. Students with high fear of failure, but high self-compassion make it possible to manage the negative impact of fear of failure and ultimately student engagement increases. This study aimed to determine the role of self-compassion in mediating the relationship between fear of failure and student engagement. The sample in this study was 384 students who were taken using the convenience sampling technique. Data were collected using three scales, namely the student engagement scale, the self-compassion scale, and the fear of failure scale. Data analysis was conducted using mediation analysis with JASP to test the mediating role of self-compassion and PROCESS analysis to see the dynamics of the relationship between the three variables in more detail. The mediation analysis results showed a significant relationship between fear of failure and student engagement in Sebelas Maret University students through self-compassion. The mediating role of self-compassion provides a greater influence than the direct effect. Increasing fear of failure allows a decrease in self-compassion. Furthermore, an increase in self-compassion allows for an increase in student engagement.
Clinical research on intravitreal injection of bevacizumab in the treatment of macula lutea and retinal edema of ocular fundus disease.

Field: Medicine (Health Sciences)

This paper aimed to explore clinically curative effect of intravitreal injection of bevacizumab in the treatment of macula lutea and retinal edema of ocular fundus disease. The number of 300 patients (390 eyes) with ocular fundus diseases including retinal vein occlusion (RVO), diabetic retinopathy (DR), age-related macular degeneration (ARMD), central serous chorioretinopathy (CSC), choridal new vessel (CNV) received and cured in the hospital from February 2010 to February 2014 were given intravitreal injection of bevacizumab (1.5mg) with once per month and a total of 2-3 times. Results of patients' vision and fluorescence fundus angiography (FFA), optical coherence tomography (OCT) before and after treatment were compared and curative effects were evaluated. Vision of 349 eyes (89.49%) improved obviously with the average of more than 2 lines, patient's intraocular pressure (IOP) was normal and all indexes were clearly better; vision of 26 eyes (6.67%) was stable before the treatment and without any changes after the treatment, the situation of fundus got better without increased IOP; vision of 15 eyes (3.85%) decreased to some extent, and the symptoms eased slightly after symptomatic treatment. In the 1st day after intravitreal injection, best-corrected visual acuity increased to 0.239±0.175, best-corrected visual acuity in 1 m was 0.315±0.182, in 3m continuously climbed to 0.350±0.270, and in 6 m was 0.362±0.282. Compared with vision before injection, t value was t=3.184, t=7.213, t=9.274 and t=9.970 (P=0.002, P=0.000, P=0.000 and P=0.000) respectively, and all P were less than 0.01. Furthermore, the difference was significant if a=0.01, which could confirm that 1m best corrected visual acuity of patients after intravitreal injection improved clearly in combination with before injection and 3m and 6 m visions enhanced constantly after injection. To sum up, intravitreal injection of bevacizumab in treating ocular fundus disease improves patient's vision effectively, also relieves macula lutea, retinal edema and other symptoms obviously, and promotes the hemorrhage absorption of vitreous body and retina.
IDENTICAL‐TWIN HYBRIDS OF CITRUS X PONCIRUS FROM STRICTLY SEXUAL SEED PARENTS

Field: Agricultural and Biological Sciences (Life Sciences)

Tree characters of 13 sets of twin and triplet hybrids from single seeds of crosses of Citrus × Poncirus and characters of three other Citrus twin sets are described. Evidence from tree size and habit, leaf size, shape, and thickness, and time of leafing and leaf fall indicates that these twins and triplets are probably all genetically identical within sets. Recent cytological evidence is cited which indicates that supernumerary sexual embryos can occur in Citrus by a process of budding from the primary embryo. The twin and triplet hybrids are clearly of separate origin from multiple asexual seedlings, also normally genetically identical, which arise fram cells of the nucellus in many Citrus varieties.
Evaluation of the Potential Targets of Shenxian–Shengmai Oral Liquid in Treating Sick Sinus Syndrome Based on Network Pharmacology and Molecular Docking

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

ABSTRACT Shenxian–Shengmai (SXSM) is a Chinese patent medicine used in the treatment of sick sinus syndrome (SSS). However, its active chemical compounds and the underlying molecular mechanisms remain unclear. In this study, we researched the underlying mechanisms of SXSM in treating SSS. We conducted network analysis and molecular docking to identify the small molecules and core targets responsible for the therapeutic efficacy of SXSM on SSS. In vitro experiments were performed to verify the potential therapeutic mechanism. Network pharmacological analysis identified 17 core targets. Among these, BMP4, KCNH2, KCNMA1, and KCNQ1 were identified to be involved in various biological processes, such as the formation and regulation of the cardiac pacemaking system and potassium ion transmembrane transport. The experimental analysis revealed that SXSM could upregulate the expression of the Bmp4/Tbx3/Hcn4 pathway and the expression of Kcnh2 , Kcnma1 , and Kcnq1 channels, which protected and improved the pacemaking function of pacemaker cells (P cells) and increased the heart rate. These findings provide a scientific basis in the study of the mechanism of traditional Chinese medicine in the treatment of SSS.
Experiences of Creating a Pranic Energy Ball by Anganwadi Female Workers as a Road to Inducing Wellbeing: A Qualitative Study

Field: Health Professions (Health Sciences)

Introduction: Prana is the subtle energy and is essential to keep the body healthy and alive.Objective: The present study was conducted to understand the experiences of creating a Pranic energy ball by Anganwadi Female workers which were felt between the hands, aimed at as a way of inducing emotional wellbeing.Methods: Qualitative method, content analysis was used to study the written responses made by the participants (N=51). Results:The results were analysed and eight themes were identified.To name a few, Pranic energy experience can enhance Positive feelings, Pranic ball can be created. Conclusions:The creation of Pranic energy ball between the hands is a simple phenomenon and can be learnt easily.
Analysis the UNHCR's MHPPS program in handling refugee mental health through the memory and world politics approach in Indonesia

Field: Social Sciences (Social Sciences)

This study examines the role of the UNHCR’s Mental Health and Psychosocial Support (MHPSS) program in addressing the mental health challenges of refugees, through the lens of memory and world politics. It examines how collective memories shaped by the trauma of displacement affect refugees’ mental health, and how this impacts refugees’ postrecovery in third countries. By applying a world politics approach, this study highlights the role of international relations, policies and geopolitical dynamics in shaping the effectiveness of mental health support for refugees. The findings suggest that while the MHPPS has made significant strides in providing psychological support, the impact of collective memories and the political environment of refugees in host countries still hinder the healing process. The study highlights the need for more context-sensitive interventions that consider both the emotional wounds experienced by refugees and the political realities surrounding displacement. In conclusion, this study advocates a more integrated approach to mental health support by strengthening partnerships between international, national and local actors to create a more inclusive and sustainable framework for supporting refugee mental health.
Synthesis of graphite by chlorination of iron carbide at moderate temperatures

Field: Materials Science (Physical Sciences)

Synthesis of graphite by extraction of iron from iron carbide by chlorine is reported in this work. This process is attractive because it can produce well-ordered graphite at temperatures as low as 600 °C, providing an opportunity for low-temperature solid-state synthesis. Thermodynamic simulation was used to determine the composition of the reaction products under equilibrium conditions and select the initial process parameters such as temperature and chlorine/carbide molar ratio. The interlayer spacing and crystal size of the produced graphite were calculated from X-ray diffraction measurements. The degree of orientation of the graphitic layers was determined by Raman spectroscopy. Three temperature regimes have been identified. At temperatures below 500 °C, amorphous or disordered carbon is formed as shown by Raman spectroscopy and TEM studies. Well-ordered graphite microcrystals are formed by solid-state growth between 600 and 1100 °C. Above the eutectic temperature in the Fe/Fe3C system, 1130 °C, the growth of large graphite crystals occurs from the liquid phase, similar to the formation of kish graphite by precipitation of carbon at high temperatures from supersaturated molten iron. Iron chlorides, the main impurities in the material synthesized by the solid-state growth, can be removed by using excess chlorine gas or by a separate wet chemical purification step. Preparation of graphite doped with iron for catalytic purposes is also possible using this process.
Baseline carcinoembryonic antigen (CEA) serum levels to predict bevacizumab-based treatment response in patients with KRAS exon wild-type metastatic colorectal cancer (mCRC) receiving 1st-line therapy with FOLFIRI plus cetuximab or bevacizumab (AIO KRK0306, FIRE3 trial).

Field: Medicine (Health Sciences)

3581 Background: Recently, Prager et al. proposed the hypothesis that carcinoembryonic antigen (CEA) is involved in tumor angiogenesis and therefore might predict bevacizumab-based treatment response in metastatic colorectal cancer (mCRC) (Cancer Research, 2013; Cancer Science, 2014). The present study aimed to evaluate this hypothesis in the FIRE-3 trial where patients (pts) with KRAS exon 2 wild-type mCRC were randomized to receive first-line chemotherapy with either FOLFIRI + cetuximab (cet) or FOLFIRI + bevacizumab (bev). Methods: Baseline CEA levels were analyzed either as continuous variable (ln) or categorized in two groups ( ≤ / > 25% quartile; ≤ / > 6.2ng/ml) with regard to their predictive impact on PFS and OS in the two different treatment arms. Correlations relied on Cox regression analysis. Survival was estimated by Kaplan-Meier. Results: For analysis of CEA, 522/592 pts (cet: 257 pts; bev: 265 pts) were eligible. When CEA baseline level was evaluated as a continuous variable, CEA (ln) was inversely correlated with PFS (p= 0.02) and OS (p= 0.001) in the bev arm, but not in the cet arm. Using the 25% quartile of CEA as a cut-off, only in the bev arm an effect on OS (24.2 mo vs. 33.3 mo; HR 0.60; Cl95%:0.41-0.88; p= 0.009) and PFS (10.4 mo vs. 11.7 mo; HR 0.67; Cl95%:0.48-0.94; p= 0.02) was observed, but not in the cet arm. Pts with high CEA baseline levels ( > 6.2ng/ml) showed a shorter OS in the bev arm compared to the cet arm (bev: 24.2 mo vs. cet: 30.0 mo; HR 1.52; Cl95%:1.16-2.00; p= 0.002). In pts with low CEA baseline level ( ≤ 6.2ng/ml) no significant survival difference was observed between arms (HR 0.92; Cl95%:0.58-1.44; p= 0.70). Univariate analysis identified CEA as an independent predictor of OS in the bev arm, but not in the cet arm. Conclusions: The present analysis supports the hypothesis that CEA acts as a predictor of bev activity, while outcome parameters in the cet arm are not affected by baseline CEA. Patients with elevated CEA baseline levels appeared to benefit from anti-EGFR directed therapy, while anti-VEGF based treatment was inferior.
12 Nutrition support for critically ill children – a review of paediatric dietetic resources in the UK and Ireland

Field: Health Professions (Health Sciences)

Objective

To characterise dietetic staffing levels in Paediatric Intensive Care Unit (PICU) within United Kingdom (UK) and Republic of Ireland (ROI).

Study Design

A cross-sectional electronic survey was developed to gather data on type of PICU, number of beds, types of nutrition guidelines available and amount of dietetic resource dedicated to the provision of nutrition support. Paediatric Critical Care Society recommends a minimum dietetic staffing to critical-care bed ratio of 1:10, with the lead dietitian being Agenda for Change (AfC) Band 7. Participants were dietitians working within PICU. No demographic data collected. PICANET database used to identify all hospitals with PICU beds. One response required per PICU. The survey was open for 12 weeks. One whole time equivalent (WTE) was 37.5h/week. PICU dietetic WTE provision was compared to recently published adult equivalent.

Results

92.8%(n=26/28) PICUs have funded dietetic service. Only 14% (n=4/28) trusts met the recommended 1:10 dietitian: bed ratio. PICU dietetic WTE was 0.7±0.4 WTE, with a staff to bed ratio of 1:22.5±11.7, compared to adult staff ratio of 1:24.7. 90%(n=25/28) had a AfCBand7 Lead but only 3%(n=1/28) had an AfCBand8a Lead vs. adult services where 12.5%(n=15/122) were AfCBand8a (p<0.05). 75%(n=22/28) of units had nutrition-guidelines, with 46%(n=13/28) children reviewed daily/2–3 per/wk. PICU dietetic staffing per bed between those who were reviewed daily/2-3per/wk compared by referral was 1:19.5±6.5 compared to 1:24.1±12.1.

Conclusion

A dedicated intensive care dietitian, as part of the PICU multidisciplinary team, contributes to improved delivery of nutrition support to all PICU patients. Results suggest the majority of PICUs within the UK and ROI do not meet minimum dietetic staffing standards. There is a significant disparity between adults and Paediatric services with regards to seniority levels. Dietitians in well-resourced centres were more likely to offer prospective review, without the need for a referral.
Highly Sensitive Room‐Temperature Detection of Ammonia in the Breath of Kidney Disease Patients Using Fe2Mo3O8/MoO2@MoS2 Nanocomposite Gas Sensor

Field: Materials Science (Physical Sciences)

Abstract A novel Fe 2 Mo 3 O 8 /MoO 2 @MoS 2 nanocomposite is synthesized for extremely sensitive detection of NH 3 in the breath of kidney disease patients at room temperature. Compared to MoS 2 , α‐Fe 2 O 3 /MoS 2 , and MoO 2 @MoS 2 , it shows the optimal gas‐sensing performance by optimizing the formation of Fe 2 Mo 3 O 8 at 900 °C. The annealed Fe 2 Mo 3 O 8 /MoO 2 @MoS 2 nanocomposite (Fe 2 Mo 3 O 8 /MoO 2 @MoS 2 ‐900 °C) sensor demonstrates a remarkably high selectivity of NH 3 with a response of 875% to 30 ppm NH 3 and an ultralow detection limit of 3.7 ppb. This sensor demonstrates excellent linearity, repeatability, and long‐term stability. Furthermore, it effectively differentiates between patients at varying stages of kidney disease through quantitative NH 3 measurements. The sensing mechanism is elucidated through the analysis of alterations in X‐ray photoelectron spectroscopy (XPS) signals, which is supported by density functional theory (DFT) calculations illustrating the NH 3 adsorption and oxidation pathways and their effects on charge transfer, resulting in the conductivity change as the sensing signal. The excellent performance is mainly attributed to the heterojunction among MoS 2 , MoO 2 , and Fe 2 Mo 3 O 8 and the exceptional adsorption and catalytic activity of Fe 2 Mo 3 O 8 /MoO 2 @MoS 2 ‐900 °C for NH 3 . This research presents a promising new material optimized for detecting NH 3 in exhaled breath and a new strategy for the early diagnosis and management of kidney disease.
Managing technology push through marketing testbeds: The case of the Hi Tech Center in Vienna, Austria

Field: Business, Management and Accounting (Social Sciences)

The `technology push' approach to technology development rests on the assumption that if you make it, they will come. This assumption carries significant market risk. The technology may miss its intended market window, or the market that was anticipated at the inception of technology development no longer exists at the time of market release. This paper discusses how the Hi-Tech Center in Vienna, Austria, a multi-national collaborative effort between industry and universities in Central Europe, helps its clients manage technology push by deploying the marketing testbed approach. After identifying lead users for a client's technology, it characterizes and determines optimal market entry dates and windows of opportunity; readiness for and resistance to adoption; technology acceptance and marketability; and best practices for market entry. The Hi-Tech Center learned the following overarching lesson from engaging with six clients in six different industries: marketing testbeds comprise an effective toolkit for managing technology push, primarily because they act as a link between the technology readiness level and the market readiness level. Thus they provide early insight into the customer's willingness to pay, the degree of fit between key features of the technology and marketability criteria, and, by extension, potential return on investment.
External validation of the PRECE nomogram model in a Central America cohort

Field: Medicine (Health Sciences)

Introduction: This is an external validation study of the PRECE prostate cancer nomogram in a Central American population. Methods: We present 102 consecutive cases of robotic radical prostatectomy, performed with preservation of the anterior fascia and we use the PRECE nomogram as a guide to preserve the prostatic neurovascular pedicles. We compared the predicted extra-capsular extension from the PRECE nomogram to the final prostatectomy pathology. Results: Analysis of post-prostatectomy pathological samples revealed that 61% patients had pT2; 27% had a pT3a and 12% had a pT3b, respectively The ROC curve for the PRECE nomogram at one (1) mm showed a model AUC of 0.91 (95% CI), which implies a high agreement with the PRECE nomogram in the prediction of extraprostatic disease. Conclusion: This is the first report of external validation of the PRECE nomogram in a Central American population. PRECE demonstrated high discrimination for the prediction of extraprostatic disease in an independent Latin American cohort. More external validation studies, from different geographic settings, are expected to confirm the reliability and reproducibility of PRECE in other clinical settings.
[Current aspects of diagnosis and therapy of iron deficiency anemia in pregnancy].

Field: Medicine (Health Sciences)

Anaemia is one of the most common risk factors in the area of obstetrics and perinatal medicine. During pregnancy and in the puerperium it is associated with an increased incidence of both maternal and fetal morbidity and mortality, the extent of which is dependent upon the severity of anaemia and the resulting complications. In order to correctly diagnose the type and degree of anaemia, a prerequisite for selection of the proper therapy, one must first of all correctly differentiate between the relative, i.e., the physiological anaemia of pregnancy due to the normal plasma volume increase during pregnancy, and "real anaemias" with various different pathophysiological causes. When defining the Hb cutoff value for anaemia in pregnancy, the extent of the plasma volume changes with respect to the gestational age must be taken into consideration. It has been found that haemoglobin values < 11.0 g/dl in the first and third trimesters, and < 10.5 g/dl in the second trimester may point to an anaemic situation which should be further clarified. The first important steps for diagnosing anaemia in a pregnant patient include a thorough check of her medical history and a medical examination. This procedure often lays the basis for a correct diagnosis. The current gold standard to detect iron deficiency remains the serum ferritin value. To be reliable, this requires the ruling out of an infection (chronic or acute) as a cause of the anaemia. We recommend a complete laboratory test for the exact haematological status as well as the assessment of specific chemical laboratory parameters. These should include a palette of additional, promising new parameters such as hypochromic red cells and transferrin receptors which allow more accurate detection of iron deficiency and differential diagnosis of iron deficiency anaemia. After correct diagnosis, major emphasis should be put on safe and effective treatment of anaemia which again depends on severity of anaemia, time for restoration and patients characteristics. Today effective alternatives to oral iron only or blood transfusion such as parenteral iron sucrose complex and in selected cases also recombinant erythropoietin have been investigated and show promising results concerning effective treatment of anaemia during pregnancy and postpartum.