jimnoneill/paper-to-field-training huggingface dataset:
Identification of Lymphocyte Subsets in Lung Cancer Tissue Using Monoclonal Antibodies

Field: Medicine (Health Sciences)

Subsets of the infiltrating lymphocytes in lung cancer tissues of 64 patients were identified by immunohistochemical staining (ABC method) using monoclonal antibodies (Leu 2a, Leu 3a+b, Leu 4, Leu 7 and Leu 14). T cells were predominant in lung cencer tissues, and tended to infiltrate into cancer cell nests and stoma, diffusely and focally. On the contrary, B cells in most cases were observed to infiltrate focally apart from cancer cells. There was a significant reverse correlation between the intensity of the T cell infiltration and the tumor T factors, and also between Th/i cell infiltration and the tumor T factors. Th/i cells were more prominent in lung cancer than Ts/c cells, and Ts/c cells scarcely infiltrated. NK, K cells also infiltrated scarcely and sparsely, and there was no correlation between the intensity of NK, K infiltration and the clinical condition. It was concluded that immunohistochemical examination of infiltrating lymphocyte subsets in lung cancer can reveal direct local immune responses and may be a useful method for making prognoses.
Sex Work for the Middle Classes

Field: Social Sciences (Social Sciences)

Drawing from fieldwork and interviews with middle-class sex workers, this essay considers the relationship between the class-privileged women and men who are increasingly finding their way into sex work and more generalized patterns of economic restructuring. How has the emergence of new communications technologies transformed the meaning and experience of sexual commerce for sex workers and their customers? What is the connection between the new `respectability' of sexual commerce and the new classes of individuals who now participate in commercial sexual transactions? This essay concludes by exploring some of the key transformations that are occurring within middle-class commercial sexual encounters, including the emergence of `bounded authenticity' (an authentic, yet bounded, interpersonal connection) as a particularly desirable and sought-after sexual commodity.
The Initial Conditions of Stellar Protocluster Formation: III. The Herschel counterparts of the Spitzer Dark Cloud catalogue

Field: Physics and Astronomy (Physical Sciences)

Galactic plane surveys of pristine molecular clouds are key for establishing a Galactic-scale view of the earliest stages of star formation. For this reason Peretto & Fuller (2009) built an unbiased sample of IRDCs in the 10 deg < |l| < 65 deg, |b|<1 deg region of the Galactic plane using Spitzer 8micron extinction. However, in absorption studies, intrinsic fluctuations in the mid-infrared background can be mis-interpreted as foreground clouds. The main goal of the study presented here is to disentangle real clouds in the Spitzer Dark Cloud (SDC) catalogue from artefacts due to fluctuations in the mid-infrared background. We constructed H_2 column density maps at ~18" resolution using the 160micron and 250micron data from the Herschel Galactic plane survey Hi-GAL. We also developed an automated detection scheme that confirms the existence of a SDC through its association with a peak on these Herschel column density maps. Detection simulations, along with visual inspection of a small sub-sample of SDCs, have been performed to get better insight into the limitations of our automated identification scheme. Our analysis shows that 76(+/-19)% of the catalogued SDCs are real. This fraction drops to 55(+/-12)% for clouds with angular diameters larger than ~1 arcminute. The contamination of the PF09 catalogue by large spurious sources reflect the large uncertainties associated to the construction of the 8micron background emission, a key stage towards the identification of SDCs. A comparison of the Herschel confirmed SDC sample with the BGPS and ATLASGAL samples shows that SDCs probe a unique range of cloud properties, reaching down to more compact and lower column density clouds than any of these two (sub-)millimetre Galactic plane surveys.
Comparison of electrode technologies for dry and portable EEG acquisition

Field: Engineering (Physical Sciences)

Clinical evaluation of electroencephalogram (EEG) is essential for monitoring the electrical activity present in the brain. In collusion with engineering advances, the movement towards portable, rapid and low-cost EEG acquisition and monitoring is growing. A low-cost and portable system for neonatal EEG is presented in this paper that aims to improve signal quality and robustness, while decreasing the preparation time and efforts required to complete a routine EEG recording. Several novel designs of dry, wet, active and passive electrodes are presented and compared with the standard EEG acquisition method using objective tests and subjective assessment by an epileptologist. It is shown that sufficient quality is achievable using dry setups, such as microneedle electrodes, with minimal patient preparation for the acquisition of clinical grade recordings.
On the reliability of self-reported health: Evidence from Albanian data

Field: Social Sciences (Social Sciences)

This paper investigates the reliability of self-assessed measures of health using panel data collected in Albania by the World Bank in 2002, 2003 and 2004 through the Living Standard Measurement Study project. As the survey includes questions on a self-assessed measure of health and on more objective health problems, both types of information are combined with a view to understanding how respondents change their answers to the self-reported measures over time. Estimates from random effects ordered Probit models show that differences in self-reported subjective health between individuals are much more marked than those over time, suggesting a strong state dependence in subjective health status. The empirical analysis also reveals respondent consistency, from both a subjective and an objective viewpoint. Self-reported health is much more influenced by permanent shocks than by more transitory illness or injury.
Muscle Biopsy in Diagnosis of Neuromuscular Disorders: The Technical Aspects, Clinical Utility, and Recent Advances

Field: Medicine (Health Sciences)

Skeletal muscle biopsies present unique preparatory challenges to the histotechnologist and unique diagnostic challenges to the clinician and pathologist. A muscle biopsy sample does not proceed through conventional fixation, nor is it processed via routine surgical pathology paraffin methods. A muscle biopsy must be dealt with as fresh tissue whose subsequent processing is a low-temperature freezing method that is ideally accomplished in a timely manner after surgical excision for optimal staining results. A panel of histological (nonenzyme) and enzymatic staining methods should be used on every muscle biopsy for full and complete clinical diagnostic results. Electron microscopy and immunohistochemistry may add valuable information in some cases. Many of these special procedures are not undertaken in the standard histology laboratory and are sent to specialized referral laboratories for testing and interpretation.The aim of this review is to reveal and summarize the unique aspects of muscle biopsies to ensure that any laboratory faced with handling a muscle biopsy will be prepared to take the correct action for optimal processing results. We also introduce the reader to muscle pathology and discuss the clinical utility of muscle biopsy in diagnosis of patients with neuromuscular disorders. (The J Histotechnol 30:257, 2007)Submitted September 24, 2007; accepted with modifications October 8, 2007
The many “costs” of transportation: Examining what cancer caregivers experience as transportation obstacles

Field: Health Professions (Health Sciences)

Abstract Background Transportation has been identified as a specific source of burden for cancer caregivers. This study examined cancer caregivers' subjective experiences and objectives costs associated with transportation over a 6‐month period of providing end‐of‐life care to a family member or friend. Methods This was a multi‐site longitudinal, prospective cohort study that followed 223 caregiver–patient dyads. Data were collected using biweekly, semi‐structured interviews for up to 6 months and collection of all caregiving related receipts. Interviews were coded and analyzed using a comparative, iterative analysis and actual out of pockets costs were described using descriptive statistics. Results Over the 6‐month study period most caregivers ( n = 143; 74%) discussed transportation at one or more timepoints. Average biweekly transportations costs to caregivers were $43.6. Caregivers described ( n = 56; 39%) multiple direct and indirect costs of transportation, and 58% ( n = 84) discussed the need for transportations services or assistance at the institutional level. Conclusions Caregivers described the multifaceted costs of transportation they experienced which are in line with previous work. Alongside descriptions of direct costs, caregivers described key opportunity costs, such as personal and work time forgone to transporting patients. Caregivers also made suggestions for institutional and/or civic based solutions to facilitate reliable modes of transportation, rather than individual‐level intervention.
Research and Implementation of the Power Equipment Inverter Switching Algorithm

Field: Engineering (Physical Sciences)

Frequency control technology can achieve the purpose of energy saving of power equipment, but also bring problems of harmonic loss formula.The relationship between the loss rate and load rate is constituted by formula derivation, and calculate the load rate when the loss rate is the minimum and the total power of power-consuming devices.Then design the digital PID controller and research the power-saving optimization feedback algorithms and design the software process.Finally, carry out the inverter switching algorithm based on ABB ACS510 low voltage inverter.
Amicrobial pustulosis of the folds: Report of 4 cases

Field: Medicine (Health Sciences)

Amicrobial pustulosis of the folds ( APF ) is a rare disease characterized by aseptic pustular lesions involving cutaneous folds, typically occurring in the context of an autoimmune disorder. We present 4 patients with APF , focusing on clinical and histopathologic characteristics to improve the recognition of this entity. All 4 patients had intertriginous and extra‐intertriginous involvement. Common histopathologic features of skin biopsies in these patients were intracorneal, subcorneal, intraepidermal, perivascular, perifollicular and interstitial neutrophilic inflammation. Pustules overlying adnexal ostium and papillary dermal edema were consistently observed. The pustules were negative for microorganisms on stain testing. In these cases, associated conditions were undifferentiated connective tissue disease, systemic lupus erythematosus, antiphospholipid syndrome, Crohn disease and Hashimoto thyroiditis. The aforementioned clinical and histopathologic characteristics of patients with suspected or diagnosed connective tissue disorders should lead to suspicion for APF .
Negotiating “Local” Food: Eastern Part Indonesia Narratives and Perspectives

Field: Social Sciences (Social Sciences)

Calls for local food in Eastern Indonesia are often dominated by sago. Still, this attention is overshadowed by continuously glorifying rice as the primary staple, ignoring regional contexts and cultural identities. Through a collaborative forum called the Food Festival Archipelago (FFA), we engaged students in sharing their stories about local food to explore their experiences, imaginations, and cultural ties to Eastern Indonesian cuisine. Using creative methods such as podcasts, short stories, Instagram posts, and videos, we discovered that Java-centric food politics have distanced students from their local food heritage. This disconnection forces many to rely on elders to rediscover traditional food knowledge, highlighting a critical loss of cultural identity. This initiative amplifies marginalized food narratives and serves as an act of resistance against global hegemony, fostering resilience through re-localization efforts. Furthermore, our findings underscore the importance of strengthening food sovereignty and local cultural identity in policy discussions, addressing the challenges posed by modernization while celebrating the rich culinary heritage of Eastern Indonesia.
The relationship between interpersonal intelligence and linguistic intelligence with mathematics learning achievement in high school students

Field: Psychology (Social Sciences)

In teaching, the teacher emphasizes identifying the dominant intelligence and learning styles to improve student achievement. However, exploring interpersonal and linguistic intelligence and its relationship to student achievement is still rarely done. This correlational research was conducted to describe the relationship between interpersonal and linguistic intelligence with high school students' mathematics learning achievement. The samples of this study were students of class XI SMA Budi Dharma Cancar Indonesia (n=30). The data were collected using a questionnaire and the pure grades of the students' midterm exams. The data analysis technique uses Product Moment Correlation as a statistical test tool to test the hypothesis of the relationship between two variables after fulfilling the prerequisite test. The results showed a positive relationship between interpersonal and linguistic intelligence and students' mathematics learning achievement. Although this study was limited to two bits of intelligence, it is essential to note that the findings of this study indicate that the number of intelligence at the dominant level can predict learning achievement in school.
Detection of Leaks in a Small-scale Water Distribution Network based on Pressure Data – Experimental Verification

Field: Engineering (Physical Sciences)

This paper presents results of research carried out so far during a national project named Aquarius (2012-2014) granted by the National Centre for Research and Development in Poland. The project was granted to the consortium of partners including Adaptronica sp. z o. o. (coordinator), Department of Environmental Engineering of the Warsaw University of Technology and Telium J. Klimkowski, D. Warowny s.c. The objective of the project is to implement a system for detection of leaks and optimal control of flow in water distribution networks (WDNs) based on pressure measurements. The leak-detection system will be supported by an electronic system for remote transfer of measurement data using GSM protocols.
Serovar distribution of urogenital C trachomatis isolates in Germany.

Field: Medicine (Health Sciences)

Using monoclonal antibodies in a microimmunofluorescence test the distribution of C trachomatis serovars isolated in the STD out-patient clinic of the Department of Dermatology of the University of Heidelberg was determined. Of 56 isolates investigated the most frequent was serovar E with 35.7%, followed by serovar D with 28.6% and serovar F with 26.8%. This shows that the distribution of C trachomatis in Germany is very similar to that in other Western countries.
Measurement Based Modelling of In-Train Repeater Deployments

Field: Engineering (Physical Sciences)

In recent years, the demand of train-commuting nomadic users for the Internet has been a huge challenge for train and mobile operators. Consequently, train operators have started to deploy in-train repeater systems to increase mobile users' service quality. These systems generally follow the structure of static deployments. However, in contrast to a static deployment where the system is set up once using constant parameters that are based on an initial measurement, the train will commute in dense urban city centers and sparsely populated rural areas. We propose a holistic model that helps to understand the role of each system component, namely, cabin pathloss, repeater model, window penetration loss, and outdoor pathloss, in which each individual element can be measured independently. We parametrize the model by measuring an existing in-train repeater deployment of a high-speed train. Finally, we have analyzed the operation of the complete system for two extreme cases of deployment strategy: simple rural and optimized track side. We show that the main benefit of the tested system is visible in the nonoptimized rural deployment. However, the optimized deployment also benefits from the repeater setup.
The Analytical Approach that Determines the Sand Drain Space by Consolidation Drainage Method

Field: Engineering (Physical Sciences)

Based on the engineering practices,the Paper analyzes the impact of sand drain space on the consolidation degree and proposes the analytical approach that determines the sand drain space by consolidation drainage method.With this approach,the postconstruction settlement analysis will be done based on the specific working condition and the deformation character of soft earth.And after the required consolidation degree that satisfies the postconstruction settlement of soft foundation obtained,the sand drain space shall then be defined based on the consolidation character of soft soil and construction period requirement.The case analysis result shows that the sand drain space defined by this approach is reasonable with satisfactory technical and economic effect.
ETIKA PROFESI KEGURUAN TINJAUAN HADITS RASULULLAH SAW

Field: Arts and Humanities (Social Sciences)

In an Islamic perspective, for a reference to the ethics of the teacher profession which can refer to the guidance of the Prophet Muhammad, because he as an apostle has a superior quality personality as a teacher and guide.The ethics of the teaching profession includes the ethics of the teacher towards himself, among others, being able to be responsible for his scientific insight and expertise and having to practice the knowledge he has in order to benefit himself and benefit others. Teachers' ethics towards their students, they understand the condition of their students, try to transfer knowledge to students until they understand, uphold self-esteem, integrity and never demean their dignity. Teachers' ethics towards peers include, among other things, that teachers should not make false statements regarding the qualifications and competence of peers and not cause conflicts with peers. Teacher ethics towards parents of students include teachers trying to foster effective and efficient cooperative relationships and deliberation in carrying out the educational process. Teacher professional ethics towards the community, among others, teachers must have the ability to communicate well with the community. Teacher ethics in this case concerns their concern for social problems, mutual cooperation, mutual assistance, egalitarianism (equality between humans), tolerance, and so on.
Eksistensiell psykoterapi

Field: Psychology (Social Sciences)

Existential psychotherapy is a pluralistic tradition with a background in existential philosophy and humanistic, experiential and psychodynamic therapy traditions. A basic premise is that psychological difficulties arise when we encounter difficulties in dealing with emotional pain that is at once specific to our own individual lives, and at the same time related to common human concerns. This may be due to a lack of the inner tools to deal with emotions or of access to the kind of contact with others that can make the pain bearable. It may also have to do with being constrained by self-interpretations that lead us to believe that emotions, needs and passions can harm or destroy. The aim of existential therapy is to help enable the patient to be present in their own life, such as it is, with curiosity, humility and awe, and to constructively engage with both the possibilities and the limitations that inevitably are there. Keywords: existential psychotherapy, therapy traditions, emotional pain, therapeutic aims
Integrated Population Exposure–Response of Dolutegravir in HIV‐1 Supports Bridging of Clinical Response Influenced by Relevant Intrinsic and Extrinsic Patient Characteristics

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Dolutegravir (DTG) is a human immunodeficiency virus type 1 (HIV‐1) integrase strand transfer inhibitor indicated in combination with other antiretroviral agents for the treatment of HIV‐1 infection in adults and pediatric subjects aged at least 4 weeks. The present work aimed to characterize the viral response based on a pooled analysis of exposure–response (E–R) from five studies in treatment‐experienced and integrase‐resistant (INI‐r) patients infected with HIV‐1. Importantly, model‐based simulations of the E–R relationships with DTG provided insight into the clinical relevance of known intrinsic (e.g., sub‐population with Q148‐driven integrase mutation) and extrinsic (food, enzyme inducers, and metal cation‐containing products) factors expected to influence the DTG E–R relationship. Model‐based post hoc exposure metrics ( C min and C avg ) were incorporated into a mechanistic population viral dynamic model describing the short‐term effect of DTG on log10 HIV‐1 RNA viral load over 8 or 10 days. In addition, the impact of DTG in combination with background ARTs on the 24‐week HIV RNA response was also assessed using logistic regression. There was good concordance between model‐based predictions and observed virologic response on day 10 and week 24. The E–R model‐based simulations exploring the potential impact of a higher dose (100 mg b.i.d.) of DTG in subpopulations experiencing exposure changes due to covariates did not show clinically relevant changes in virological response compared with the approved 50 mg b.i.d. clinical dose. Overall, our study confirmed the current recommendation of dolutegravir 50 mg b.i.d. in the integrase inhibitor‐resistant (INI‐r) population.
[Vesicoureteral reflux in children with prenatal suspicion of urinary tract abnormalities].

Field: Medicine (Health Sciences)

1. Indication to performing VCUG in children with prenatally detected hydronephrosis should be persistent dilatation of pyelocalyceal system and/or ureter in postnatal US or another abnormalities in UT. 2. Normal prenatal and postnatal USG does not exclude presence of VUR. 3. VCUG in children with prenatally detected hydronephrosis should be performed about 3 months of life, in specially situation earlier.