jimnoneill/paper-to-field-training huggingface dataset:
Assessment of Osgood-Schlatter Disease and the Skeletal Maturation of the Distal Attachment of the Patellar Tendon in Preadolescent Males

Field: Medicine (Health Sciences)

Background: Osgood-Schlatter disease (OSD) is a traction apophysitis of the tibial tuberosity. Ultrasonography (US) is able to detect pathologic changes, such as cartilage swelling and fragmentation of the tibial tubercle ossification center. Purpose: To compare the US stages of tibial tuberosity development and the physical features and prevalence of OSD in this patient cohort. Study Design: Cross-sectional study; Level of evidence, 3. Methods: Subjects included 238 males (n = 476 joints) with a mean age of 11.4 ± 1.6 years (range, 7-14 years). The tibial tuberosity development on US was divided into 3 stages: the cartilaginous stage (stage C), apophyseal stage (stage A), and epiphyseal stage (stage E). It was then investigated whether the subjects had pain in the tibial tuberosity on application of pressure. Age, height, body weight, body mass index (BMI), heel-buttock distance (HBD, cm), and straight-leg raise angle (SLRA) were evaluated. To confirm the diagnosis of OSD, the participant had to fulfill the following clinical criteria: pain with direct pressure on the tibial apophysis, fragmentation of the bone, and irregularity of the ossification center detected by US. Results: The tibial tuberosity was stage C in 195 knees, stage A in 105 knees, and stage E in 176 knees. The subjects’ heights, weights, and BMIs significantly increased with advancing development of the tibial tuberosity. The HBD increased in stage E ( P < .01). The SLRA was not significantly different among groups. There was fragmentation of the bone and irregularity of the ossification center in 32 knees (6.8%): 0 in stage C, 21 (4.3%) in stage A, and 11 (2.3%) in stage E. Fragmentation of the bone and irregularity were observed significantly more often in stage A ( P < .01). On the other hand, there were 10 joints with OSD (2.1%): 0 in stage C, 3 (0.6%) in stage A, and 7 (1.5%) in stage E. OSD was observed significantly more often in stage E than in the other stages ( P < .05). Conclusion: The present study showed that the HBD increased from stage A to stage E. The prevalence of OSD was highest in stage E.
Interacting with smart environments: Users, interfaces, and devices

Field: Computer Science (Physical Sciences)

A Smart Environment is an environment enriched with disappearing devices, acting together to form an entity. In such environments, the computing power pervades the space where the user lives, so it becomes particularly important to investigate the user's perspective in interacting with her surrounding. Interaction, in fact, occurs when a human performs some kind of activity using any computing technology: in this case, the computing technology has an intelligence of its own and can potentially be everywhere. There is no well-defined interaction situation or context, and interaction can happen casually or accidentally. The objective of this dissertation is to improve the interaction between such complex and different entities: the human and the Smart Environment. To reach this goal, this thesis presents four different and innovative approaches to address some of the identified key challenges. Such approaches, then, are validated with four corresponding software solutions, integrated with a Smart Environment, that I have developed and tested with end-users. Taken together, the proposed solutions enable a better interaction between diverse users and their intelligent environments, provide a solid set of requirements, and can serve as a baseline for further investigation on this emerging topic
Return to Elite-Level Basketball After Surgical Reconstruction of the Anterior Cruciate Ligament and Medial Collateral Ligament of the Knee With Meniscal Repairs–It Takes Teamwork and Time to Restore Performance: A Case Report

Field: Medicine (Health Sciences)

BACKGROUND: Return to the preinjury level of play after a 2-or-more-ligament knee injury is a challenge, with research suggesting that injury pattern and rehabilitation quality are key variables to consider. CASE PRESENTATION: A 22-year-old male basketball player suffered a 2-ligament knee injury involving the anterior cruciate ligament, medial collateral ligament, and both menisci. He underwent reconstructive surgery and completed his rehabilitation and return-to-sport training within 1 facility. OUTCOME AND FOLLOW-UP: After 12 months of extensive rehabilitation, objective testing confirmed the recovery of the athlete's surgical limb performance. He returned to his preinjury level of play and signed a professional contract to play elite-level basketball in Europe. DISCUSSION: The athlete required more than a year of extensive rehabilitation to return to elite-level basketball. After a 2-or-more-ligament knee injury, comprehensive rehabilitation programs are required to support an athlete's return to their preinjury level of play. JOSPT Cases 2022;2(4):226–233. Epub: 12 October 2022. doi:10.2519/josptcases.2022.11103
Stable isotope studies on the Greenland ice-sheet margin

Field: Earth and Planetary Sciences (Physical Sciences)

Stable isotope analysis has been used intensively in the investigation of snow and ice-cores retrieved from the central region of the Greenland ice sheet. The d 18O records from the deep ice cores drilled at Camp Century and Dye 3, for example, provided detailed climatic information for the past maybe more than 100 000 years (Dansgaard et al., 1985). However, although the marginal zone of the ice sheet is readily accessibie compared with the central region, little attention has been given to stable isotope studies in the marginal zone (the ablation zone).
A STUDY OF THE PERCEPTIONS OF ENGLISH FACULTY AND STUDENTS OF EXIT ENGLISH EXAMINATIONS AT TAIWAN'S TECHNOLOGICAL AND VOCATIONAL HIGHER EDUCATION INSTITUTIONS

Field: Social Sciences (Social Sciences)

The mix-method research aimed to investigate the attitudes toward the implementation of Exit English Examination (EEE) from the perspectives of English faculties and their students at Taiwan's technological and vocational higher education institutions. The survey participants were 66 English faculty and 1009 students in ten first-tier Universities of Technology and Institutes of Technology in Northern Taiwan based on the admission scores of the Technological and Vocational College Entrance Examination in the school year of 2009-2010. Descriptive statistics, Chi-Square tests, Mann-Whitney U tests, Kruskal-Wallis tests, and Spearman Correlation tests of the SPSS were conducted to determine the characteristics and statistically significant differences of participants' survey questions. Findings indicated the following: various factors for the faculties and students played significant roles in attitudes toward EEE implementation; motivation and desire to learn English were highest in those students with medium English performance; a majority of students perceived a stronger influence from the EEE than the faculties; influence of the EEE on future jobs was recognized by both groups, as well as the need for assistance with fees, monetary incentives, and the subsidization for financially challenged students; faculties and students had conflicting opinions in regard to teaching to the test, the curriculum, and teaching effectiveness; the qualitative data analyses was predominated by concern regarding the test standard, test choices and future jobs. Suggestions for this study included: a continuous implementation and overhaul of the EEE in Higher Education; help in facilitating professional development and a learning community; a review and adjustment of the existing English curriculum, methods and test standards; an alignment of the curriculum with the EEE standard and student preparation; a review of existing preparation programs, including monetary incentives and fees; professional assistance for juniors and seniors; utilization of international counterparts' assessment tools. Further research could include (a) covering major stakeholder's participation in decision making, implementation and gathering of information and analysis, (b) longitudinal work tracking students who failed the EEE, and (c) replicating a similar study in other geographical areas of Taiwan. Numerous implications for future studies were also provided.
CALCULATION OF MINIMUM CRITICAL REYNOLDS NUMBER FOR LAMINAR-TURBULENT TRANSITION IN PIPE FLOWS

Field: Engineering (Physical Sciences)

Abstract. This article describes the calculation of the minimum critical Reynolds number for laminar-turbulent transition in pipe flows. From the conclusions of our previous experimental study, it is clear that a transition occurs near the pipe inlet and the critical Reynolds number takes the minimum value of about 2000 in the case of a straight pipe. Moreover, in our previous calculations of laminar entrance pipe flow, it was found that near the pipe inlet a large pressure gradient in the radial direction exists, which decreases as the Reynolds number Re increases. Thus, we have built a new transition macromodel to determine using the effect of the radial pressure gradient.
Kinetics of Dimerization and Interactions of p13suc1 with Cyclin-Dependent Kinases

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The impact of p13suc1 on the conformation and regulation of cyclin-dependent kinases (cdks) and cyclins was investigated by spectroscopic and rapid kinetic approaches. In the absence of phosphorylation on cdks, p13suc1 formed stable complexes, mainly stabilized by hydrophobic interactions, specifically with cdk2 and cdc2. The presence of cyclin A, associated with cdk2 or cdc2, increased the stability of the interaction between cdk2 and p13suc1 by a factor of 2. However, cyclin A did not modify the association rate of p13suc1 to cdk2, but the dissociation rate, which was decreased 3-fold. Moreover, binding of p13suc1 to cdk2 resulted in a 2-fold decrease in the release of nucleotide from cdk2, indicating that p13suc1 induces a marked change in the structure of the nucleotide binding site of cdks. On the basis of the structure of cdk2/CksHs1 complex and on our kinetic results, we propose that the binding of Cks proteins to C-lobe of cdk2 is stabilized by the presence of cyclin A and that it may modify the orientation of the loop carrying residues 14 and 15 and their consequent access for dephosphorylation by cdc25 phosphatases. Finally, we have shown that dimerization of p13suc1 in the presence of zinc abolishes its interaction with cdks, which suggests that the binding of p13suc1 to cdk2 or cdk2/cyclin A may be regulated by dimerization of p13suc1 in vivo.
Towards analyzing the potential of exosomes to deliver microRNA therapeutics

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Exosome selectivity mechanisms underlying exosome–target cell interactions and the specific traits affecting their capability to communicate still remain unclear. Moreover, the capacity of exosomes to efficiently deliver their molecular cargos intracellularly needs precise investigation towards establishing functional exosome‐based delivery platforms exploitable in the clinical practice. The current study focuses on: (a) exosome production from normal MRC‐5 and Vero cells growing in culture, (b) physicochemical characterization by dynamic light scattering (DLS) and cryo‐transmission electron microscopy; (c) cellular uptake studies of rhodamine‐labeled exosomes in normal and cancer cells, providing to exosomes either “autologous” or “heterologous” cellular delivery environments; and (d) loading exogenous Alexa Fluor 488‐labeled siRNA into exosomes for the assessment of their delivering capacity by immunofluorescence in a panel of recipient cells. The data obtained thus far indicate that MRC‐5 and Vero exosomes, indeed exhibit an interesting delivering profile, as promising “bio‐shuttles,” being pharmacologically exploitable in the context of theranostic applications.
Connecting Adolescents With Their Geographically Separated Parents: Videoconferencing for Reading Support

Field: Social Sciences (Social Sciences)

Prolonged separation from a parent has been linked to emotional and academic consequences among children. Therefore, in this article, the authors used free videoconferencing to (a) deliver parental support for a student struggling with reading and (b) maintain a nurturing relationship between a geographically separated father and son. The authors explain how to set up and conduct the parent–child videoconference with information gleaned from trying the procedures. In addition, the authors suggest how to use the practice to foster better home–school partnerships in education. The use of web technologies seems to be a promising means of making a student resilient to the potential academic and emotional consequences of separation from a parent.
Which Trading Agent is Best? Using a Threaded Parallel Simulation of a\n Financial Market Changes the Pecking-Order

Field: Computer Science (Physical Sciences)

This paper presents novel results generated from a new simulation model of a\ncontemporary financial market, that cast serious doubt on the previously widely\naccepted view of the relative performance of various well-known public-domain\nautomated-trading algorithms. Various public-domain trading algorithms have\nbeen proposed over the past 25 years in a kind of arms-race, where each new\ntrading algorithm was compared to the previous best, thereby establishing a\n"pecking order", i.e. a partially-ordered dominance hierarchy from best to\nworst of the various trading algorithms. Many of these algorithms were\ndeveloped and tested using simple minimal simulations of financial markets that\nonly weakly approximated the fact that real markets involve many different\ntrading systems operating asynchronously and in parallel. In this paper we use\nBSE, a public-domain market simulator, to run a set of experiments generating\nbenchmark results from several well-known trading algorithms. BSE incorporates\na very simple time-sliced approach to simulating parallelism, which has obvious\nknown weaknesses. We then alter and extend BSE to make it threaded, so that\ndifferent trader algorithms operate asynchronously and in parallel: we call\nthis simulator Threaded-BSE (TBSE). We then re-run the trader experiments on\nTBSE and compare the TBSE results to our earlier benchmark results from BSE.\nOur comparison shows that the dominance hierarchy in our more realistic\nexperiments is different from the one given by the original simple simulator.\nWe conclude that simulated parallelism matters a lot, and that earlier results\nfrom simple simulations comparing different trader algorithms are no longer to\nbe entirely trusted.\n
The current state of legal regulation of the release of civil servants: positive and negative aspects

Field: Social Sciences (Social Sciences)

The specificity of the legal regulation of passing civil service in Ukraine (labor relations with civil servants) is that it is at the same time implemented by the rules of labor legislation and the rules of special legislation on civil service. The dismissal from the civil service is the final stage of its passage, which is accompanied by the loss of the civil servant status. Legal regulation of the order of civil servants dismissal is carried out taking into account the priority of special norms over the general ones, that is, first of all, the provisions of the Law of Ukraine “On Civil Service” apply. This article explores the current state of regulation of dismissal of civil servants. It has been established that it is a dismissal of civil servants and what are the grounds for it. It is determined how the dismissal of civil servants at each stage of this process is regulated. Positive and negative aspects of the current state of legal regulation of the dismissal of civil servants are highlighted.
Dickens’ Use of Character as Novelty

Field: Arts and Humanities (Social Sciences)

Research Article| July 01 1962 Dickens’ Use of Character as Novelty Archibald C. Coolidge, Jr. Archibald C. Coolidge, Jr. Search for other works by this author on: This Site Google South Atlantic Quarterly (1962) 61 (3): 405–410. https://doi.org/10.1215/00382876-61-3-405 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation Archibald C. Coolidge; Dickens’ Use of Character as Novelty. South Atlantic Quarterly 1 July 1962; 61 (3): 405–410. doi: https://doi.org/10.1215/00382876-61-3-405 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsSouth Atlantic Quarterly Search Advanced Search The text of this article is only available as a PDF. Copyright © 1962 by Duke University Press1962 Article PDF first page preview Close Modal You do not currently have access to this content.
Mental Health Literacy and Self-Stigma on Intention to Seek Professional Psychological Help

Field: Psychology (Social Sciences)

This study aims to determine the effect of mental health literacy and self-stigma on the intention to seek professional psychological help in the mental health community. Data collection using research instruments from the Mental Health Literacy Scale (MHLS), The Self Stigma of Seeking Psychology Help (SSOSH-10), and the TPB Questionnaire on Mentalhealing.id community members who joined in the application Telegram (n=100). Data were analyzed using the Multiple Linear Regression analysis. The results of this study indicated that there is a significant effect of mental health literacy and self-stigma on the intention to seek professional psychological help in the mental health community (Fvalue= 20,501; Ftable= 2.36; p<0.10). The level of intention to seek professional psychological help is in a good category, which is 61%.
Effect of beta-galactosidase on the spin-coated lipid layer of a lipid sponge phase as a carrier for enzyme by ATR-FTIR

Field: Chemistry (Physical Sciences)

Transport in and through biological membranes that consist of lipid bilayers has a crucial role in many applications in the food or pharmaceutical industries. How to deliver an enzyme through the membranes without damaging the enzymatic activity or the shelf-life of the enzyme has been of large interest since 1970 [29-30]. In this work, we have shown that a thin lipid sponge phase (L3) layer can be formed on adiamond crystal of an attenuated total reflectance (ATR) accessory for Fourier transform infrared (FTIR).The lipid system used was composed of diglycerolmonooleate (DGMO), glycerol monooleate - Capmul GMO-50 (GMO-50) and the nanoparticle stabilizer polysorbate 80 (P80) in ethanol (EtOH). In this coated lipid layer, the enzyme beta-galactosidase (beta-gal) could be immobilized and characterized by the catalysis of lactose. Beta-galactosidase is an important enzyme in the food industry that is used to hydrolyze lactose to glucose and galactose for making lactose-free milk or other dairy products that are important for lactose intolerant peoples. We investigated by ATR-FTIR the catalytic response of the enzyme in lipid layers coated at different spinning times on the crystals and different concentrations of enzyme. The FTIR signals that are related to the catalytic process of beta-gal were identified at561 cm-1 and 582 cm-1 in the Infrared spectrum. The obtained signal belonged to the produced glucose. Furthermore, to understand the effect of spin-coating and enzyme activity as well as the best condition in term of maximizing the glucose formation- and lipid signals decrease rates for the system and technique, we designed a factorial experiment combining different spinning times (drop-casting, 20and 300 s) and enzyme dilution factors (10, 50 and 100 times). The optimal condition for the highest catalytic rate and lowest disturbance of the lipid signal was further used to investigate the re-usability of the encapsulated enzyme. No conclusions about the re-usability of the encapsulated enzyme could not be drawn from the experiment due to the unreliable collected data. (Less)
Neonatal Profile and Outcome in Neonatal Intensive Care Unit Sanglah Hospital

Field: Medicine (Health Sciences)

Children face the highest risk of dying in their first month of life, at an average global rate of 2.5 million deaths in 2018. The highest neonatal mortality rate in 2018 occurred in Sub-Saharan Africa which reached 28 deaths per 1000 live births, followed by East Mediaterania with 25 deaths per 1000 live births. Meanwhile, based on Central Bureau of Statistics, the neonatal mortality rate in Indonesia were 15 deaths per 1000 live births in 2017. More than 80% death in neonates caused by 3 preventable factors such as complication of prematurity, complication of birth like asphyxia and neonatal infection (such as sepsis and pneumonia). Furthermore intensive care unit play crucial role in critically ill neonate. In this study we aimed to determine profile and outcome of neonates treated in Neonatal Intensive Care Unit (NICU) of Sanglah Hospital. This was a descriptive cross sectional study and data was taken retrospectively from medical record of neonates treated in NICU during 2019. We got 393 neonates admitted in NICU, but forty patients were excluded due to readmission and insufficient data. Finally there were 208 (62.1%) male neonates and 127 (37.9%) female neonates, with 208 subjects were premature neonates (<37 weeks). Their median length of stay was 7 days. Most cases were treated due to respiratory distress (84.1%). In 2019, we found 111 neonates passed away with sepsis as the most common cause of neonatal death. Neonates treated in NICU were dominated by premature neonates, male and low birth weight (<2500 gram). There was 28.2% neonatal death in 2019.
Occupational accident prevention strategies based on Behaviour Based Safety (BBS) in a selected manufacturing industry / Thurga Devi Uthaya Sooriyan

Field: Business, Management and Accounting (Social Sciences)

Behavior based safety is defined as an observation made on a particular employee to identify the level of safety practice concern when they perform a job. his study was conducted on the rubber manufacturing industry in Meru, Klang. This study was based on a three-month pilot test observation that took place only during working hours. A total of 152 employees were observed. The goal of this study is to discover the high-potential elements that cause workplace accidents in risky acts and conditions. Not only that, but following the pilot test, to provide a procedure on how BBS can be implemented. Each hazard factor and subfactor discussion included cost-effective ideas for preventing or reducing the number of accident instances. In this study, action plans were considered in relation to the needs of the rubber manufacturing business, and statistical output was analyzed. Due of mischievous behavior, safety behavior is acknowledged to be a main source of accident occurrence. Therefore, several strategies were provided and discussed for a long-term benefit with a slow in progress period. Highly encouraged to conduct safety trainings and frequent assemblies to highlight the importance of safety practice. As for the cost-effective solution for the data collected in this study has been proposed to set up a system which can help to record data’s and to monitor improvements. Safety committees are encouraged to set up an inhouse system for non-conformance tracking and rectifications. For future studies, research study can be done on developing a BBS predictive analytical dashboard system to predict the future outcome hazards and to work on the possible solutions for the hazards.