jimnoneill/paper-to-field-training huggingface dataset:
Investigating a Seven-Day Baseline While Establishing Healthy SCAT3 Symptom Frequency and Severity

Field: Medicine (Health Sciences)

Second only to a clinical exam, symptom checklists are used to aid in the evaluation of concussions. The validity of symptom checklists can become compromised by nonconcussed linked conditions that can vary day to day and are not taken into consideration during a baseline test. The purpose of this study was to assess the day-to-day reliability of the SCAT3 Symptom Evaluation and to determine the frequency and severity of the 22 symptoms in a nonconcussed, adult, athletic population. This study used a repeated-measure observational design and required participants to complete an online version of the SCAT3 Symptom Evaluation multiple times over a 7-day period. Moderate day-to-day reliability was found for the frequency and severity of symptoms and all of the 22 symptoms were reported by at least one participant. The results of the study suggest that the current practice of collecting the baseline symptoms once does not account for any day-to-day variation in symptoms and also demonstrates that all of the 22 symptoms listed on the SCAT3 Symptom Checklist can be present in nonconcussed, adult athletes.
The Role of Parents in Guiding Children's Learning Activities at Home

Field: Social Sciences (Social Sciences)

This study aims to determine the role of parents in guiding learning activities from home in fourth-grade elementary school students. This type of research is descriptive qualitative research. This research was conducted at SDN Kaliwadas 01. The source of data used was primary data using interviews with teachers, parents and students, and secondary data in the form of documentation. The informant selection technique in this study used a purposive sampling technique. Analysis of the data used in this study using an interactive analysis model from Miles and Huberman which consists of data collection, data reduction, data presentation, and drawing conclusions. The results of this study on the role of parents in guiding learning activities from home during the covid-19 pandemic, the results of interviews, observations, and documentation regarding the role of parents in learning from home, there are several problems found in parents when guiding learning activities from home, some of these problems can conclude in this study: the lack of students in understanding the material so that it requires parents to study material that is not in their field, limited facilities, especially in terms of quotas, parents' educational backgrounds. The active role of parents in mentoring learning, directing children to study well, limiting children from playing with gadgets and parents providing facilities for children.
Chaperone–usher pathways: diversity and pilus assembly mechanism

Field: Immunology and Microbiology (Life Sciences)

Up to eight different types of secretion systems, and several more subtypes, have been described in Gram-negative bacteria. Here, we focus on the diversity and assembly mechanism of one of the best-studied secretion systems, the widespread chaperone–usher pathway known to assemble and secrete adhesive surface structures, called pili or fimbriae, which play essential roles in targeting bacterial pathogens to the host.
The expression of moesin in laryngeal carcinoma and its related clinical factors

Field: Medicine (Health Sciences)

OBJECTIVE To evaluate the expression of moesin (membrane-organizing extension spike protein)in laryngeal carcinoma and its related clinical factors. METHODS RT-PCR (reverse transcription polymerase chain reaction) and immunohistochemistry methods were used to investigate the expression of moesin in normal epithelium tissues adjacent to cancer, laryngeal carcinoma tissues in 58 patients and in metastastic lymph nodes in 25 patients. RESULTS The result of RT-PCR showed that the expression of moesin in normal epithelium tissues adjacent to cancer(0.086±0.063), laryngeal carcinomas(0.599± 0.301) and metastastic lymph nodes(0.731±0.096)had signif icant difference (F=132.456, P0.001). The results of immunohistochemistry showed that the expression of moesin gradually increased in normal epithelium tissue adjacent to cancer, laryngeal cancers and metastastic lymph nodes(P0.05), which is related with the clinical stages, T grading, the metastasis of cervical glands and pathology grading(P0.05), but no relation with gender, age and smoking(P0.05). CONCLUSION Moesin is a membrane/actin f ilament protein involved in dynamic restructuring of the cell surface and f ilopodia, a cell structure needed for cell adhesion and motility, which may play an important role in the process of invasion and metastasis of laryngeal carcinoma.
Added Value of Concomitant Systematic and Fusion Targeted Biopsies for Grade Group Prediction Based on Radical Prostatectomy Final Pathology on Positive Magnetic Resonance Imaging

Field: Medicine (Health Sciences)

Grading concordance between biopsy pathology and radical prostatectomy pathology was improved by adding systematic biopsy in all patient subgroups. Patients with prostate specific antigen density less than 0.20 ng/ml/gm benefited the most from this combined biopsy strategy. Systematic biopsy reclassified a nonnegligible number of cases toward a higher risk category, mainly the low risk cases. Thus, systematic biopsy could modify treatment decision making.
Neurobiology of Disease Physiological Regulation of the �-Amyloid Precursor Protein Signaling Domain by c-Jun N-Terminal Kinase JNK3 during Neuronal

Field: Neuroscience (Life Sciences)

�-Amyloid precursor protein (APP) is a conserved and ubiquitous transmembrane glycoprotein strongly implicated in the pathogenesis of Alzheimer’s disease but whose normal biological function is unknown. Analogy to the Notch protein suggests that APP is a cell-surface receptor that signals via sequential proteolytic cleavages that release its intracellular domain (AICD) to the nucleus. Because these cleavages are major targets for therapeutic inhibition, it is critical to elucidate their physiological function. AICD is stabilized by Fe65, interacts with the transcriptional factor Tip60, and translocates to the nucleus. Here, we show that endogenous AICD in primary neurons is detectable only during a short period of time during differentiation in culture. During this transient rise, a portion of AICD localizes to the nucleus. Subsequently, phosphorylation of the APP cytoplasmic domain at threonine 668 appears to disrupt the stabilizing interaction with Fe65 and thus downregulate AICD-mediated signaling. Furthermore, we find that the neuron-specific c-Jun N-terminal kinase JNK3, but not JNK1 or JNK2, mediates a substantial portion of this phosphorylation. We conclude that endogenous AICD undergoes tight temporal regulation during the differentiation of neurons and is negatively regulated by JNK3 via phosphorylation of APP at Thr668. Key words: amyloid precursor protein; AICD; JNK; Alzheimer’s disease; phosphorylation; signaling mechanism
Clinical Lecture on a Case of Hydropneumothorax

Field: Medicine (Health Sciences)

GENTLEMEN,-I hlave already lectured more than once on the varying phases of the following case as they have presented themselves succes- sively during the life of the patient.I propose now, in the first place, to repeat the sumn and substance of my preceding lectures, and then to describe and commenit upon the mode of dying and the revelations of the dead-house.I use the term hydropneumothorax, in its widest acceptation, to denote the presence of fluid of any kind along with air in the pleural cavity.John Brygenshaw, aged 22, was admitted originally on the I2th of August last, under Dr. Cayley, to whom I am indebted for the pre- liminary notes up to the date of his discharge in October.His own antecedents and his family history were good; his appearance was that of a healthy and well-made man.On admission, the heart was found beating most distinctly in the third right interspace, just beyond the sternum; there was considerable apparent bulging on the left side, which was dull from apex to base, and failed to expand on deep inspiration.The breath-sound was feeble everywhere, quite inaudible towards the base of the lung, fairly blowing at the front apex, where there was comparatively little resonance.August I5th.The left side measured I84 inches, the right I7T. August I7th.Paracentesis was performed by Mr. Hulke between the sixth and severth ribs, and 98 ounces of clear serum, of specific gravity I020, were withdrawn.During the operation, the heart re- turned towards its normal position.August 2Ist.There was fair resonanice in front as far as the fourth rib; in the axilla, to the level of the fifth; and at the back, as far as the angle of the scapula.September i6th.Friction-sounds were audible over the left front.'There was diulness anteriorly below the fourth rib, and posteriorly from the base of the luing up to the middle of the scapula.Over the dull space, the breathingr was feeble and bronchial ; and there was an cgophonic twang with the voice.October 3rd.The patient left the hospital for Eastbourne without any signs of pneumothorax.October 23rd.Ile returned from Eastbourne.He never lost his
IODP Expedition 347, Hole M0060B - Well Logging Data

Field: Earth and Planetary Sciences (Physical Sciences)

Logging data are measurements of physical properties of the formation surrounding a borehole, acquired in situ after completion of coring (wireline logging) or during drilling (Logging-While-Drilling, LWD). The range of data (resistivity, gamma radiation, velocity, density, borehole images,…) in any hole depends on the scientific objectives and operational constraints.
Response to Letter Regarding Article, “Direct Intramyocardial but Not Intracoronary Injection of Bone Marrow Cells Induces Ventricular Arrhythmias in a Rat Chronic Ischemic Heart Failure Model”

Field: Medicine (Health Sciences)

Intramyocardial but Not Intracoronary Injection of Bone Marrow Cells Induces Ventricular Arrhythmias in a Rat Chronic Ischemic Heart Failure Model"We thank Dr Ly for his interest in our article. 1We, too, strongly believe that cell therapy as a treatment for heart failure requires further laboratory research to ensure its future success.It is likely that not only the injection site, but also the number and volume of injections and the number of cells injected, will influence therapeutic benefit and arrhythmogenicity after intramyocardial cell injection. 2Although this is an important clinical point, its illustration in small animal models has obvious limitations; large animal or human studies are needed.Dr Ly's assertion that skeletal myoblasts are too large to be injected via an intracoronary route may not be right.We have demonstrated previously that both antegrade and retrograde intracoronary injections of skeletal myoblasts are effective for treating heart disease. 3,4e do not aim to insist that retrograde intracoronary injection is superior to antegrade infusion.However, it is a fact that transendothelial migration of donor cells injected via antegrade intracoronary injection is seriously limited.Our data (K.S., S.F., A.V
Brown coal planning as a basis for sustainable settlement development

Field: Environmental Science (Physical Sciences)

Abstract The paper describes the transformation process of the East-German brown coal mining in connection with the reorganization of the power industry after the political change in 1989. The objectives of this transformation process is the reduction of heavy environmental pollution, primarily the reduction of SO2- and airborne particles and past pollutions, as well as the mine reclamation stopping the further degradation of settlements with technical infrastructure. The paper focuses on the elaboration of brown coal mining plans for living and abandoned mining as integral parts of the regional plans in Saxony. The principle of the primary integration of landscape planning into regional planning organizing land use and settlement development will be explained. Based on the Chinese planning system starting points for planning developments in China will be discussed.
Extracting, evaluating biological activities of phenolic compounds from yellow onion peels (Allium cepa L.) and their applicability for fish preservation

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract The research aimed to evaluate total phenolic content extracted from onion ( Allium cepa L.) peels and some of the extract biological activities. The potential of the extract for preserving fish was also investigated. Onion peel extracted with EtOH 60% at 60°C (60 minutes, solid/liquid ratio 1g/20ml) yielded highest polyphenol content 168.49 ± 0.02 GAE/g DW and flavonoid content (216.43 ± 0.06 mg QE/g DW). The extract showed potent antioxidant property in DPPH radical scavenging assay with IC 50 value of 12.48 ± 0.45 μ/mL and good antibacterial activity against Bacillus subtilis, Escherichia coli, Staphylococcus aureus, Salmonella, Pseudomonas aeruginosa with MIC values of 175; 175: 200; 200: 150 (μ/mL) respectively. The extract also displayed alpha-glucosidase inhibition activity with IC 50 value of 142.53 μg/mL and negligible tyrosinase inhibition activity. Measurement of the PV, TBARS values of basa catfish fillets coated with the extract solution at different concentrations, it was observed that fish samples treated with 3% extract solution could greatly reduce the lipid oxidation under 4°C and -18°C storage conditions compared with untreated samples. The PV, TBARS values after 4 weeks were comparable to 200ppm BHT treated samples.
Robust time-varying Kalman smoothers with uncertain noise variances

Field: Mathematics (Physical Sciences)

This paper addresses the design of robust Kalman smoothers for the time-varying system with uncertain noise variances. According to the minimax robust estimation principle, and the unbiased linear minimum variance (ULMV) optimal estimation rule, based on the worst-case conservative system with the conservative upper bounds of noise variances, two robust Kalman state smoothing algorithms are presented by the augmented and non-augmented state approaches, respectively. Their robustness is proved by the Lyapunov equation approach, and their robust accuracy relations are proved. A simulation example is given to verify the robustness and the correctness of the robust accuracy relations.
Molecular characterization of a strain-specific sequence in Campylobacter jejuni

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Campylobacter jejuni strains 81116 and NCTC 11392 were shown to contain a region of DNA that was not present in other strains. This region was cloned from the chromosome of strain 81116 and the nucleotide sequence determined. It was found to contain an insert of 742 bp which was flanked by direct repeats of 45 bp. Although the nature of this sequence is unknown at present, it is clear that it only presents in certain strains of Camp. jejuni and it may therefore be useful as an epidemiological tool.
Reflections on Interactions in virtual worlds and their implication for learning art and design

Field: Arts and Humanities (Social Sciences)

As more educators venture into virtual worlds there is a need to consider the impact that these worlds have on the interactions between learners and teachers. The paper explores what is known about the impact of computer mediated communication and relates it to rich interactive 3d virtual environments. It recommends areas for consideration when using these spaces for art and design related activities The review of the literature reveals that many of the emotions and norms found in social interaction in the real world also transfer to the virtual world. Virtual worlds offer opportunities for engaging student centred activities but these require careful planning if they are to be successful.
Microwave-Assisted Synthesis of 5-Substituted 3-Amino-1,2,4-triazoles from Aminoguanidine Bicarbonate and Carboxylic Acids

Field: Chemistry (Physical Sciences)

The effect of the molar ratio between reagents, reaction time and temperature on the yield of 5-substituted 3-amino-1,2,4-triazoles obtained by the direct condensation of carboxylic acids with aminoguanidine bicarbonate under acid catalysis conditions was studied. As a result, a general green straightforward synthesis of the title compounds bearing aliphatic substituents or a phenyl ring was developed using sealed reaction vials under controlled microwave synthesis conditions that are suitable for the application of volatile starting carboxylic acids. Our straightforward synthetic method proposed in this work increases the synthetic accessibility of these widely used building blocks and therefore is able to significantly expand the structural diversity of compounds containing a triazole moiety for the needs of drug discovery.
Combining Faculty, Instructional Design, and Library Services to Provide Students a Framework for Information Evaluation

Field: Social Sciences (Social Sciences)

The creation of the course-embedded Critical Thinking & information Evaluation Module series resulted from the need for undergraduate students to start their academic careers with a framework for evaluating information. Pulling from the Paul-Elder Critical Thinking Framework and focusing abstract information literacy concepts on the commonly-used resources of Wikipedia, Google, and scholarly journal articles, the presenters will delve into module creation to implementation of these modules and discuss the logistics of this process to guide other faculty-librarian-instruction designer collaborations.
The Impact of Liver Steatosis on Interleukin and Growth Factors Kinetics during Chronic Hepatitis C Treatment

Field: Medicine (Health Sciences)

Background/Objectives: Various biological response modifiers play important roles in the immunopathogenesis of chronic hepatitis C (CHC). While serum levels of cytokines and growth factors change with the disease severity and treatment responses, the impact of concomitant liver steatosis on systemic inflammatory response is largely unknown. The aim of this study was to analyze the characteristics and kinetics of serum profiles of interleukins and growth factors in CHC patients with steatotic liver disease (SLD). Methods: Serum concentrations of 12 cytokines (IL-5, IL-13, IL-2, IL-6, IL-9, IL-10, IFN-γ, TNF-α, IL-17A, IL-17F, IL-4 and IL-22) and 6 growth factors (Angiopoietin-2, EGF, EPO, HGF, SCF, VEGF) were analyzed in 56 CHC patients at four time points (baseline, week 4, week 8 and SVR12) with bead-based flow cytometry assay. Results: At baseline, patients with SLD had significantly lower IL-9, IL-10, IL-13 and IL-22 and higher serum concentrations of EGF, VEGF and ANG. In a subgroup of patients with advanced liver fibrosis, SLD was linked with lower serum concentrations of IL-4, IL-5, IL-9, IL-10, IL-13 and IL-22 and higher concentrations of HGH and VEGF. Distinct cytokine kinetics during DAA treatment was observed, and SLD was identified as the main source of variation for IL-5, IL-9, IL-10, IL-13, IL-17A, IL-22, EGF, VEGF and ANG. Patients with SLD at SVR12 had significantly higher VEGF and HGF serum concentrations. Conclusions: SLD is associated with distinct cytokine and growth factor profiles and kinetics during CHC treatment, which might be associated with disease severity and the capacity for liver regeneration and contribute to fibrosis persistence.
The Beetles of the United States (A Manual for Identification)

Field: Agricultural and Biological Sciences (Life Sciences)

Journal Article The Beetles of the United States (A Manual for Identification) Get access The Beetles of the United States (A Manual for Identification) . Arnett Ross H. . Section 1, Fascicles 1-9, xi + 210 p., illus. The Catholic University of America Press , Washington, D. C.$3.50 (subsequent sections priced according to number of pages), binder $3.95 . Completed work $25.00 , $28.95 with binder. Lewis Berner Lewis Berner Department of Biology, University of Florida . Search for other works by this author on: Oxford Academic Google Scholar AIBS Bulletin, Volume 11, Issue 6, December 1961, Page 34, https://doi.org/10.2307/1292930 Published: 01 December 1961
Fearnsides, William George, (10 Nov. 1879–15 May 1968), MIME; Professor Emeritus of Geology, University of Sheffield, 1945; Hon. Fellow, Sidney Sussex College, Cambridge, 1946

Field: Earth and Planetary Sciences (Physical Sciences)

"Fearnsides, William George, (10 Nov. 1879–15 May 1968), MIME; Professor Emeritus of Geology, University of Sheffield, 1945; Hon. Fellow, Sidney Sussex College, Cambridge, 1946" published on by Oxford University Press.
Differences in relative mRNA expression levels of molecules relevant for renal fibrosis among NCAM positive cells from normal and renal interstitium with incipient fibrosis, obtained by laser capture microdissection.

Field: Medicine (Health Sciences)

<p><b>(A)</b> Relative mRNA expression levels of various molecules relevant for renal fibrosis; data are presented with mean values and standard error bars; *- indicate statistically significant difference, p<0.05; graph is made of mean values in order to unify variable presentations, although only αSMA, SLUG and ALK3 followed normal distribution; thus, some variables differed extremely among cases and consequently these data did not display normal distribution; due to influence of these extreme values on the mean value presented in the graph, bars are high but without statistical significance (such as BMP7); Student’s t test was used for variables with normal distribution both in control and kidneys with fibrosis: αSMA, SLUG and ALK3; due to high variability of other variables, exclusively in diseased kidneys, we applied nonparametric Mann Whitney U test to assess the difference in mRNA levels between controls and diseased kidneys; there were 6 samples (2 cases in triplicates) of control cases and 42 (14 cases in triplicates) samples of cases with incipient renal fibrosis. <b>(B)</b> NCAM positivity in peritubular incipient interstitial fibrosis shown on cryostat section, immunofluorescene, clone EP257Y, x400. <b>(C)</b> MMP-9 positivity in peritubular incipient interstitial fibrosis shown on cryostat section, immunofluorescence, clone 6-6B, x400. <b>(D)</b> arrows indicate the overlapping of NCAM and MMP-9 in interstitial cells.</p>