jimnoneill/paper-to-field-training huggingface dataset:
Deadlock Recovery for Flexible Manufacturing Systems with Exhaustive Exploration of the Reachability Graph

Field: Computer Science (Physical Sciences)

In the article a novel deadlock recovery policy for flexible m a nufacturing systems, modelled by the Petrinets, proposed. Deadlocks in manufacturing systems are costly, as then the system gets stuck in one of its states and does not evolve. The proposed policy is based on full reachability graph analysis and considers the paths from deadlock markings to preceding legal markings. As a result, the system may recover from all deadlock markings and continue its operation, and - at the same time - the number of recovery transitions added to the basic Petri net is minimal and the existing state space is not modified. The introduced policyisil lustrated with some weI known examples from the literature and confronted with the different approaches. The preliminary results indicate that the proposed deadlock recovery policy achieves good results in the respect of added recovery transitions.
Apricot Seeds as a Source of Dehydrogenases

Field: Agricultural and Biological Sciences (Life Sciences)

Increasing interest in various aspects of the mechanism of biological oxidation has developed a need for rich and reliable sources of dehydrogenases. An attempt was made to find such sources in appropriate plant material because of the possibility that such material might have an advantage in cheapness and in ease of handling. With the exception of yeasts, plants do not seem to have been much explored for dehydrogenases. Three samples of yeast from different manufacturers were found to be relatively poor sources for dehydrogenases, and samples from the same source varied greatly in such enzyme activity. Preliminary search through representative available plant sources indicated the relative richness in dehydrogenases of the coatings of the seeds of various species of Prunus. With the skins removed, the seeds contain almost no dehydrogenases but are rich in lipases and emulsin. Such vegetables as beets and potatoes seem to be poor sources of dehydrogenases. Seeds of legumes and cereals are reported to be good sources of lactic dehydrogenase. Representative assay data on dehydrogenase content are shown in Fig. 1 for extracts from beets, potatoes, yeast and seed coatings of almond, cherry, peach and apricot. Of these materials apricot seed coatings appear to be richest in dehydrogenases. In extracting the dehydrogenases from fruit seeds, the seeds were first soaked for 24 hours in cold water to each liter of which one-half cc. of toluene was added. The skins were removed and extracted in a ball mill with disodium phosphate containing toluene, for 6 hours. To one liter of phosphate, 100 gm. of wet seed skins were added. The first extract contained most of the lactic and formic dehydrogenases. This was filtered and the skins extracted for another 6 hours with disodium phosphate. This second extract contained most of the malic, tartaric, and oxalic dehydrogenases. It was sometimes possible to separate lactic dehydrogenase from formic dehydrogenase by adsorbing the latter on alumina in acid buffer of pH 6.5. Formic dehydrogenase was then eluted with disodium phosphate. The phosphate filtrates were neutralized with dilute acetic acid and the enzyme precipitated with 5 volumes of 95% ethyl or methyl alcohol. The precipitate was centrifuged, washed with 95% alcohol, then ether, and dried in a vacuum desiccator over calcium chloride. The resulting material is gray and brittle.
The Impact of Restrictive Measures on the Price Discovery Function of Stock Index Futures – Evidence From CSI 500 Stock Index Futures

Field: Economics, Econometrics and Finance (Social Sciences)

Restrictive measures implemented by governments have a great impact on the price discovery function of stock index futures. This study compares the price discovery function of CSI 500 stock index futures and CSI 500 stock index before and after the implementation of restrictive measures based on the reaction speed to new information, the price ratio of new information and the price contribution of both future market and spot market. It also analyzes the difference between the price discovery function of the future market and that of the spot market and thus proposes policy implications accordingly.Utilizing data of CSI 500 stock index futures in the period of the stock market crash, this study compares the price discovery function before and after the implementation of restrictive measures. By means of the VECM model and common factor analysis, it further investigates the difference in the price contribution of the two markets. Contributing to existing literature on the relationship between the future market and the spot market, this study explores the change in the price contribution of the two markets and therein studies the impact of restrictive measures on the price discovery function. Empirical evidence finds that before the implementation of restrictive measures, the price discovery function worked more efficiently, while, however, after the implementation of restrictive measures, the price discovery function did not work. Hence, stock index futures do assist in the price discovery of the spot market. In some special time periods, however, due to the impact of restrictive policies, the price contribution of the spot market exceeded that of the future market, implying that the price discovery function of the CSI 500 stock index future market is unstable.
Evaluating School-Based Programming for Pregnant and Parenting Adolescents

Field: Social Sciences (Social Sciences)

The Children and Adolescent Support and Self-Sufficiency (CAPSS) program serves pregnant and parenting adolescents eligible to attend an urban school district in the Midwest. It employs a Youth Development Framework promoting connections with caring adults. While pregnancy prevention has become a major initiative for schools, programming to help meet the educational needs and social needs of teen-aged mothers has attracted much less attention. This paper provides some early results from an evaluation of a program designed to keep teen-aged mothers in school, to improve their parenting skills, to lessen the likelihood that they will become pregnant again, and to prepare their children for success in school. (Contains 10 references.) (Author) Reproductions supplied by EDRS are the best that can be made from the original document. Evaluating School-Based Programming for Pregnant and Parenting Adolescents by Julie Fenyk Geoffrey Maruyama Katherine Seiden Lorna Pain Ann Hoxie Poster Presented at the 2003 APA Conference in Toronto U.S. DEPARTMENT OF EDUCATION Office of Educational Research and Improvement EDUCATIONAL RESOURCES INFORMATION CENTER (ERIC) 0 This document has been reproduced as received from the person or organization originating it. 0 Minor changes have been made to improve reproduction quality. Points of view or opinions stated in this document do not necessarily represent official OERI position or policy.
Non-Proportionality and Energy Resolution of CsI(Tl)

Field: Physics and Astronomy (Physical Sciences)

Experimental studies of CsI(Tl) crystals with different amounts of Tl activator are presented. Properties such as non-proportionality, energy resolution and the number of photoelectrons per 1 MeV-gamma were inspected at two different shaping time constants, i.e., 3 and 12 mus. A CsI(Tl) crystal was coupled to the XP5212 PMT with a photocathode blue sensitivity of 12.2 muA/lmF. Six CsI(Tl) crystals of different sizes were tested. Among them, three samples were of known Tl concentration, which amounted roughly 0.05, 0.1 and 0.25 mol%. The data analysis showed a much more proportional character of the crystal response, higher number of photoelectrons/MeV-gamma, and consequently, a better overall energy resolution obtained for 12 mus time constant for all tested samples. The calculated intrinsic resolution improved for longer shaping time constants as well, indicating that, for CsI(Tl) crystals, a more proportional response implies better intrinsic energy resolution of the host crystal. In contrast, the intrinsic resolution at the low energy region (below about 30 keV) deteriorated for the longer shaping time constant. An alpha/gamma ratio was also measured for each tested CsI(Tl) crystal in order to find any indication of an explanation of the intrinsic resolution deterioration for low energy photons at the 12 mus integration time.
Significant reforms in public sector audit – staying relevant in times of change and challenge

Field: Business, Management and Accounting (Social Sciences)

Purpose – This paper aims to talk about the changes to auditing practice in the context of broader changes in the public sector. Design/methodology/approach – A personal reflection on the issue using prior experiences as a former auditor-general of two Australian states. Findings – The role for government audit will always mirror the change in the public sector. Whether audit fulfils this role depends on having the right legislation and the right approach. While audit legislation lags behind recent shifts in public sector approaches, government auditors are continuing to explore new ways to give parliament, as well as the sector, authoritative opinions and commentary that is relevant and valuable. Practical implications – Increased understanding of the changing role of the Auditor-General's Office that affects the efficiency and effectives of public sector entities will help practitioners in improving strategic directions of their operations. This will also help academic researchers in developing ideas for future research. Originality/value – Reflections presented here are based on the author's practical experiences over the past 40 years as a program manager and as a government auditor.
Support for High Performance Real-time Collaboration within the NaradaBrokering Substrate

Field: Computer Science (Physical Sciences)

The requirements for collaborative services, especially pertaining to order and delivery, are quite different compared to traditional distributed applications. The NaradaBrokering messaging substrate enables scalable, fault-tolerant, distributed interactions between entities, and is based on the publish/subscribe paradigm. The substrate also incorporates support for Grid and Web Service. More recently, we have incorporated services within the substrate which enable us to facilitate richer collaborative interactions. In this paper, we outline our rationale for incorporating these services and how these services interact with each other. We have conducted experiments related to profiling these services, and also on the performance and scaling of the messaging substrate. Our experimental results demonstrate that the substrate can indeed be used in scenarios where performance and scalability requirements are stringent.
Visual Journalism and the Future of News Consumption

Field: Arts and Humanities (Social Sciences)

This chapter reviews the rise of immersive technologies, with a particular emphasis on visually immersive forms that have only begun to be implemented in newsrooms and social media platforms over the past decade. The road leading to today's technology has been a long and winding one, and it will likely take a while before the public views news as an immersive experience. This chapter will also serve to introduce the customization and personalization of new technologies in the future, as well as the problems that may accompany them over the next 20 to 40 years and beyond.
Chronic antigen-specific T helper 17 inflammatory responses in the lungs require persistent adjuvant exposure to be sustained

Field: Immunology and Microbiology (Life Sciences)

Abstract Allergic asthma is characterized by exaggerated lung T helper 2 (Th2) and Th17 responses which require signals that stimulate the innate immune system, provided by exposure to environmental adjuvants with an allergen. Once airway disease has developed, it is unclear as to whether the same mechanisms that initiated the disease remain important in sustaining it. We investigated the contribution of persistent innate danger signals in sustaining a chronic antigen-specific Th17 cell response. Animals were sensitized and challenged acutely by aspiration of ovalbumin (OVA) with different adjuvants, including house dust extract (HDE). They were then challenged for a further 5 weeks with OVA alone or OVA + adjuvant to test whether the adjuvant becomes redundant in sustaining airway inflammation once it has already been established. Removal of the adjuvant during the chronic challenges resulted in the animals displaying minimal airway inflammation, whereas continuous challenge with adjuvant and OVA caused significant inflammation. HDE was particularly potent at promoting airway neutrophilia, lymphocytosis and greater IL-17A production from lung explants restimulated ex vivo with OVA, suggesting that persistent exposure to this adjuvant amplified the antigen-specific Th17 response. Furthermore, CD4+ cells from OVA-receptor transgenic (OT-II) IL-17A-fate mapping mice were differentiated under Th17 polarizing conditions and adoptively transferred to recipients which were then challenged with either OVA alone, OVA + HDE or HDE alone. Persistent exposure to HDE and OVA, compared to either one alone, amplified the lung antigen-specific memory Th17 response, independently of the enzymatic activity of HDE but rather via TLR4 signaling.
A new synthesis of methionine

Field: Chemistry (Physical Sciences)

Research Article| January 01 1931 A new synthesis of methionine George Barger; George Barger 1The Department of Medical Chemistry, University of Edinburgh Search for other works by this author on: This Site PubMed Google Scholar Theodore Edwin Weichselbaum Theodore Edwin Weichselbaum 1The Department of Medical Chemistry, University of Edinburgh Search for other works by this author on: This Site PubMed Google Scholar Biochem J (1931) 25 (4): 997–1000. https://doi.org/10.1042/bj0250997 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation George Barger, Theodore Edwin Weichselbaum; A new synthesis of methionine. Biochem J 1 January 1931; 25 (4): 997–1000. doi: https://doi.org/10.1042/bj0250997 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Journal Search Advanced Search This content is only available as a PDF. © 1931 CAMBRIDGE UNIVERSITY PRESS1931 Article PDF first page preview Close Modal You do not currently have access to this content.
Low-Luminance Contrast Stimulation Is Optimal for Early Detection of Glaucoma Using Multifocal Visual Evoked Potentials

Field: Neuroscience (Life Sciences)

BonY and LLA mfVEPs performed comparably, and both were significantly better than the HLA mfVEP in identifying early glaucoma. Enhanced performance of BonY stimulation is most likely due to its low-luminance contrast component rather than the pattern-onset mode of presentation or its chromatic properties.
Mosaics of time. The Latin chronicle traditions from the first century BC to the sixth century AD, I: A historical introduction to the chronicle genre from its origins to the high Middle Ages. By R. W. Burgess and Michael Kulikowski. (Studies in the Early Middle Ages, 33.) Pp. xiv+446. Turnhout: Brepols, 2013. €100. 978 2 503 53140 3

Field: Arts and Humanities (Social Sciences)

Mosaics of time. The Latin chronicle traditions from the first century BC to the sixth century AD, I: A historical introduction to the chronicle genre from its origins to the high Middle Ages. By R. W. Burgess and Michael Kulikowski. (Studies in the Early Middle Ages, 33.) Pp. xiv+446. Turnhout: Brepols, 2013. €100. 978 2 503 53140 3 - Volume 65 Issue 4
Isolation of High-Quality DNA from a Desert Plant Reaumuria soongorica

Field: Agricultural and Biological Sciences (Life Sciences)

Xiaohua Wang1, Honglang Xiao1, Xin Zhao2, Caizhi Li1, Juan Ren1, Fang Wang1 and Lei Pang1 1Key Laboratory of Ecohydrology and of Inland River Basin Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of Sciences, Lanzhou 2Extreme Stress Resistance and Biotechnology Laboratory Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of Sciences, Lanzhou PR China
Effect of nitrogen-containing derivatives of the plant triterpenes betulin and glycyrrhetic acid on the growth of MT-4, MOLT-4, CEM, and Hep G2 tumor cells

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Derivatives of the available plant triterpenes glycyrrhetic acid and betulin (betulin succinates and amides of betulonic and 18beta-glycyrrhetic acids containing fragments of long-chain amino acids and a peptide) were synthesized. The inhibitory action of these compounds on the growth of MT-4, MOLT-4, CEM. and Hep G2 tumor cells and their effect on the apoptosis of these cells were studied. It was shown that betulonic acid amides are more effective inhibitors of the tumor cell growth than the corresponding amides of glycyrrhetic acid. It was also found that betulonic acid amides containing fragments of caprylic, pelargonic, and undecanoic acids are more effective inhibitors of tumor cell growth than betulinic acid. The 17-dipeptide derivative of betulonic acid N-{N-[3-oxo-20(29)-lupen-28-oyl]-9-aminononanoyl}-3-amino-3-phenylpropionic acid exhibited the maximum inhibitory activity toward the tumor cells studied. Data on the induction of apoptosis in tumor cells by betulin derivatives at a concentration of 10 microg/ml were obtained by flow cytometry. The amides of betulonic acid proved to be the most effective inducers of apoptosis.
PO73 OUTPATIENT CATUMAXOMAB THERAPY IN METASTATIC BREAST CANCER PATIENTS SUFFERING FROM MALIGNANT EFFUSIONS DUE TO PERITONEAL OR PLEURAL CARCINOMATOSIS: A SINGLE INSTITUTION EXPERIENCE

Field: Medicine (Health Sciences)

s / The Breast 24 S3 (2015) S21–S75 S47 cells. Loss, increase, or no change in ER staining in primary tumour and pleural effusion specimens was observed in 7, 0 and 21 cases (19 cases were positive, 2 cases were negative), respectively. In two of these 19 cases with ER positive, endocrine therapy was performed. In one of two patients, endocrine therapy achieved long stable disease. However, endocrine therapies were ineffective in all cases of ER loss in pleural effusion specimens. No discrepancy of HER2 expression from primary tumours and pleural effusion specimens were confirmed. Positive staining cell for VEGF-A was found to be present in 75% of pleural effusion specimens (15 of 20 specimens). Eight pleural effusion specimens were not available to VEGF-A staining because of a few carcinoma cells. In 2 of these 15 cases with VEGF-A positive, bevacizumab antiangiogenic agents were administered. Therapeutic effects were confirmed in both patients. However, these agents were administered in 2 of 5 cases with VEGF-A negative and therapeutic effects were confirmed in one patient. Conclusions: The results of this study emphasize the reliability of immunohistochemistry in pleural effusion specimens. Therapeutic effect prediction based on biomarkers in the pleural effusion specimens of breast cancer patients may be promising in loss cases of ER staining.
PHYTOCHEMICAL COMPOSITION AND ANTICANCER ACTIVITY OF SEAWEEDS ULVA LACTUCA AND EUCHEUMA COTTONII AGAINST BREAST MCF-7 AND COLON HCT-116 CELLS

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective: this study is aimed to develop marine resources which is focused on the determination of phytochemical composition and exploration of seaweeds Ulva Lactuca and Eucheuma cotonii, as a potential anti-breast cancer and anti-colorectal cancer agents. Methods: Seaweeds Ulva Lactuca collected from Parangtritis beach, Yogyakarta, Central Java, Indonesia. Whereas Eucheuma cottonii collected from Salemo island, South Sulawesi, Indonesia. Seaweeds U. lactuca and E. cottonii were macerated in organic solvents, n-hexane, chloroform, ethyl acetate and ethanol, respectively. After maceration for three days, the mixture was filtered, the filtrate was concentrated by rotary evaporator. The concentrated extract of n-hexane, ethyl acetate, ethanol and chloroform were then analyzed by thin layer chromatography. Phytochemical test of the concentrated extract were conducted to identify the metabolites containing in the seaweeds. Furthermore, the cytotoxic activity of the n-hexane, ethyl acetate, ethanol and chloroform extract of Ulva Lactuca and Eucheuma cotonii were evaluated as a growth inhibitor of breast MCF-7 and colorectal HCT-116 cancer cells by MTT cell proliferation assay. Results: Phytochemical test for the concentrated extracts of Ulva Lactuca showed the positive result for metabolites of steroids, glycosides, flavonoid,and tannin. While the concentrated extracts of E. cottonii showed positive result for metabolites of steroids, glycosides, and flavonoid. Both concentrated extracts of Ulva lactuca and Eucheuma cotonii exhibited anticancer activity against breast MCF-7 and colorectal HCT-116 cells with IC50 ranging of 21 µg/mL to 99 µg/mL . Conclusion: Our results clearly demonstrate seaweeds Ulva Lactuca and Eucheuma cotonii as a promising candidates for the new anti-breast and anti-colorectal cancer agents. Keywords: Phytochemistry, Ulva Lactuca, Eucheuma cotonii , anticancer, breast MCF-7, colorectal HCT-116
ANALISIS KEPUASAN KERJA BUMN DI INDONESIA : STUDI DAMPAK FAKTOR QUALITY OF WORK LIFE

Field: Business, Management and Accounting (Social Sciences)

Human resources is able to determine the advance or retreat of an organization and plays an important role in the success of any organization. One of the main problems in human resource management is how to find the best way to achieve employee satisfaction. One way to measure the level of employee satisfaction is to know the feelings of employees towards aspects of the job (Quality of Work Life). The purpose of this study was to determine the influence of quality of work life on job satisfaction of employees of PT A. The method used is a mix method. Data analysis techniques used simple linear regression. The results of the research show that the influence of quality of work life on job satisfaction is included in the strong category with the value of the contribution amounted to 60.84%, meaning that if the quality of work life better then it will improve job satisfaction. Quality of work life is an attempt to achieve self-satisfaction and a work environment that is optimal. If job satisfaction is low will have a negative impact on PT. A such as morale decreases, productivity is low and leads to a social environment that is not healthy as well as declining employee performance.
Effectiveness and efficiency of physical and chemical mutagens in inducing viable mutations in M2 generation of mungbean (Vigna radiata (L.) Wilczek)

Field: Agricultural and Biological Sciences (Life Sciences)

Mutagenic effectiveness and efficiency of gamma rays, ethyl methane sulphonate (EMS) and sodium azide (SA) treatments were assessed in two mungbean varieties viz., WGG-42 and LGG-460 in M2 generation. Mutagenic effectiveness and efficiency were calculated in relation to biological damage in M1 and viable mutations in M2 generation. In the present study, viable mutation frequency increased with an increase in dose/concentration of mutagens, EMS showed the highest frequency of viable mutations than gamma rays and SA treatments in both the genotypes. The highest frequency of viable mutations were observed at 600 Gy of gamma rays, 0.6% of EMS and 3 mM of SA. The mutagenic effectiveness and efficiency showed a trend, which was inversely proportional to the increasing dose of mutagens used, EMS treatments were found to be more effective and efficient in inducing viable mutations followed by gamma rays and SA treatments in both the cultivars.