jimnoneill/paper-to-field-training huggingface dataset:
Reliability and validity of revised instrument on pain management and its relationship between knowledge and attitudes among nurses in Vietnam

Field: Health Professions (Health Sciences)

Objective: This study aimed (1) to evaluate the internal consistency and test-retest reliability of the Vietnamese version of the Knowledge and Attitudes Survey Regarding Pain –revised questionnaire; and (2) to assess the relationship between the knowledge, attitudes and demographic factors in nurses. Materials and methods: A cross-sectional survey and a correlation research design was used to evaluate test-retest reliability. 154 participants were tested twice with a 2-week interval. Multivariate analysis was performed by using multiple linear regressions to test the relationship between demographic data with nurse' knowledge and attitude of pain management. Results and Discussion: Reliability was confirmed by internal consistency (Cronbach α = 0.88) and test-retest reliability (intraclass correlation coefficient, 0.88). The results of multiple regression indicated that age, nurses had level 5, and nurses from internal medicine, ICU, emergency, obstetric, oncology department, those with previous education in pain management, and routinely assess pain for patients were predicted to KASRP score, accounting for 11.6%. Conclusion: The Vietnamese Knowledge and Attitudes Survey Regarding Pain- Revised questionnaire had satisfactory content validity and reliability for assessing pain management in nurses in Vietnam. Some demographic factors were predicted 11.6% of KASRP in Nurses. Further research need focus on those factors independently significant predicted to KASRP to improve nurse's knowledge and attitude. Bangladesh Journal of Medical Science Vol. 23 No. 01 January'24 Page : 160-170
10-Mbps electro-optic resonant phase modulator

Field: Physics and Astronomy (Physical Sciences)

A resonant cavity electro-optic phase modulator has been designed and implemented to operate at a data rate of 10 Mbps. The modulator consists of an electro-optic crystal located in a highly resonant cavity. The cavity is electro-optically switched on and off resonance, and the phase dispersion nearthe cavity resonance provides the output phase modulation. The performance of the modulator was measured by first heterodyne-detecting the signal to an intermediate frequency and then measuring the spectral characteristics using an rf spectrum analyzer. The measured phase shift is shown to be in good agreement with the theoretical predictions. Further theoretical analysis shows that the design of the modulator can be scaled to operate at 100 Mbps.
Abstract P1061: Crosstalk Between Acetylation And Methylglyoxal Modifications On Myofilament Proteins Affects Sarcomere Function

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Diabetes doubles the risk of developing heart failure, independent of coronary artery disease and hypertension. The mechanisms connecting these two diseases are poorly understood, although we have previously shown one connection is likely due to methylglyoxal (MGO), a highly reactive glycolysis byproduct that can irreversibly modify lysine (K) and arginine (R) residues in a process called glycation. We found MGO glycation of the myofilament decreased calcium sensitivity and maximum calcium activated force in diabetes. Here we hypothesized MGO may further impact function by competing for lysine residues that would otherwise be targets for acetylation, which has been shown to impact cardiac function. To assess this hypothesis, non-failing human left ventricular (LV) myocardial tissue was exposed to MGO (100 μM) or vehicle and then the treated with acetic anhydride in acetonitrile (300 μM, Ac 2 O-ACN) overnight. Ac 2 O-ACN increased myofilament protein acetylation in both groups, but this effect was greatly reduced in samples pre-treated with MGO, suggesting these two PTMs do compete for a subset of lysine residues. To discover the specific sites of this acetylation-glycation crosstalk, we compared mass spectrometry data sets from diabetic humans, MGO treated mouse myocytes, and acetylated myocytes, which revealed sites of crosstalk on actin, myosin, and myosin light chains - proteins essential for normal contractile function. Importantly, these glycation-acetylation crosstalk sites were found in human samples and the data suggest the balance of these may change in disease states. To explore the functional consequence(s) of this crosstalk, we incubated human LV isolated skinned myocytes with Ac 2 O-ACN (300 μM, overnight), which enhanced function by significantly increasing calcium sensitivity. However, pre-treatment with MGO (100 μM) completely blocked this functional effect of acetylation. Together, these data demonstrate that glycation and acetylation compete for certain myofilament lysine residues, and that glycation can block the beneficial functional effects of acetylation. These results provide insight into the molecular mechanisms behind diabetic cardiomyopathy and the utility of targeting acetylation clinically.
May the Fourth Be with you: Creating Education 4.0

Field: Social Sciences (Social Sciences)

The paper looks back across dominant ways of delivering Higher Education until the present day and then looks forward. There is an approximate continuum described from Education 1.0 through 2.0 to 3.0. Education is mapped onto the emergence and development of the Web and the revolutions known as ‘Industrial’ over the last 250 years. Then some foresight is deployed with the particular lens of graduates’ employment prospects and contributions to the future – dubbed ‘Education 4.0’. The paper hopes to stimulate dialogue and promote preparedness and innovation for more changes arriving fast over Higher Education’s wider horizons.
Simple Contest Enhancers

Field: Decision Sciences (Social Sciences)

Contests are an important mechanism for eliciting effort in a multi-agent setting. In this paper we introduce and analyze the benefit in two enhancers to contest design within the framework of simple contests: (a) changing the execution of the contest from parallel to sequential; and (b) adding some ambiguity to the way performance is measured. While intuitively such interventions may seem to hinder participation and performance, we show that for a large class of contest settings they actually improve the expected profit of the contest organizer. The paper presents a formal game-theoretic analysis of the different enhanced mechanisms, enabling market designers and contest organizers the means for extracting the equilibrium in each in order to properly use the methods in the contests they run.
Modeling and Analysis of Hybrid Blood Nanofluid as Drug Carriers through Artery with Rheological Effects

Field: Chemical Engineering (Physical Sciences)

In this current work, we assume the mathematical modelling of non-Newtonian time-dependent hybrid nanoparticles via a cylindrical stenosis artery. In this work, blood is used as a base fluid, and the nanoparticles (copper and aluminum oxide) of cylindrical shape are inserted inside the artery to combine with blood to form hybrid nanofluid (HNF). The homotopy analysis method (HAM) is deployed for the solution of nonlinear resulting equations. For the validation of this current work, the results of the existing work have been compared with our proposed model results. A comparison of key profiles like velocity, temperature, wall shear stress, and flow rate is also performed at a specific critical height of the stenosis. It is also observed that the thermal conductance of hybrid nanofluids is greater than that of nanofluids. Including the hybrid nanoparticles (copper and aluminum oxide) inside the blood enhances the blood axial velocity. These simulations are applicable to the magnetic targeting treatment of stenosed artery disorders and the diffusion of nanodrugs.
Early Reduction, Arthrotomy, and Cannulated Screw Fixation in Unstable Slipped Capital Femoral Epiphysis Treatment

Field: Medicine (Health Sciences)

Sixteen consecutive cases of unstable slipped capital femoral epiphysis treated with urgent reduction and pinning during a 7-year period are presented. In 2 of the 16 patients, avascular necrosis of the femoral head developed. Ten of the 16 patients were treated within 24 hours after the onset of acute symptoms by reduction, arthrotomy, and cannulated screw fixation of the hip using two screws. In none of these patients did avascular necrosis of the femoral head develop. Two patients required hardware removal for persistent pain, and one required a revision pinning after a nondisplaced femoral neck fracture. Chondrolysis did not develop in any patient, and no hip progressed after fixation. At last follow-up (mean 27 months after surgery), two patients walked with a moderate limp. Three reported persistent mild pain in the affected hip. Early reduction of unstable hips with arthrotomy and pinning using two cannulated screws to minimize the risk of avascular necrosis is recommended.
Evaluation of Pharmacodynamic Effects of Ethanolic Extract of the Leaves of Gnetum africanum on Uterine and Ovarian Tissues Morphology of Rats.

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Dynamic effect of Ethanolic extract of medicinal plant, Gnetum africanum repeated oral administration on uterine and ovarian tissues histology of rats was investigated. Three tolerated doses of the extract 10, 200 and 700 mg/kg obtained from acute toxicity test were administered orally to three respective groups of female rats daily for 3 days. On the 4 th day, rats of all the groups were sacrificed and their uteri and ovaries were carefully isolated and fixed in 10% formal-saline, for 28 days. The fixed tissues were sectioned and histologically processed and examined under light microscope. Photomicrographs of the tissue sections revealed uterine endometrial hyperplasia with formation of several tiny cysts due to glandular dilatation and formation of ovarian fibromas, cytological atypia and stroma. The findings allow the conclusion that excessive oral administration of the medicinal plant, Gnetum africanum , a popular Nigerian medicinal plant, could impact a negative influence on the female reproductive physiology. Keywords: Ethanolic Extract, leaves of Gnetum africanum , Ovarian tissues, Uterus, female rats.
Postrotatory nystagmus. Analysis of abnormal cases.

Field: Medicine (Health Sciences)

We examined postrotatory nystagmus in 43 patients with vertigo. The slow phase of postrotatory nystagmus was analyzed by a second order system represented by the following equation.y (t) =A (e-t/T2-et/T1) /T2-T1y (t) =slow phase of postrotatory nystagmus (°/sec).T1=short time constant of system of postrotatory nystagmus (sec).T2=long time constant of system of postrotatory nystagmus (sec).Calculation was done by the most-least square method and values A, T1, T2 were determined.The values of 15 healthy subjects without any ear or brain disease were used to determine the normal range.In 43 patients with vertigo the short time constant had no relation to the attacks of vertigo; however, the long time constant was shortened in parallel with the degree of vertigo.Ampllopetal flow in the affected ear, especially during vertigo, showed a shorter than normal long-time constant.We conclude that patients with vertigo have a shorter long-time constant and a low AP value. This means that patients with vertigo are intolerate of longer stimuli.
Flexible PANI/Lotus Stemmed Fiber Sensor for Bifunctional Sensing of Physical and Chemical Stimuli

Field: Engineering (Physical Sciences)

Abstract In recent times, high‐performance flexible sensors that can be fabricated environmentally friendly and low‐costly have received considerable attention owing to their potential applications in wearable health monitoring. The combination of biocompatibility, degradability, and recyclability between the substrate and sensor layer remains a challenge. Here, a highly sensitive multifunctional sensor is developed using a polyaniline (PANI)‐coated lotus stem fabric (PANI/LSF) for body physical and chemical stimuli in a simple way. The lotus stem fabric has excellent breathability, skin compatibility, and lightweight as a flexible substrate. Its high sensitivity at low pressure is experimentally verified, which can reach 0.3 kPa −1 in the 0–1.5 kPa range. In addition, the sensor has low detection limitation and good linearity of response to water molecules and short response and recovery times for water in N 2 or normal atmosphere at the range of 3.7–70.5% relative humidity (RH) and 19.6–66.8% RH, respectively. This can be successfully used in the recognition of various breathing behaviors. Therefore, the study has developed a breathable and skin‐friendly bifunctional sensor based on PANI and natural fabrics, which has great potential for application in human health care.
Arguing with technology: Teaching and learning argumentative writing in the digital age English classroom

Field: Arts and Humanities (Social Sciences)

Argumentation is an under-developed practice in secondary English classrooms where the focus of essay-writing instruction has become the testing of content and the practising of text and paragraph templates. Under these constraints students are failing to see the process or product of writing as authentic or meaningful. In one response, educational technology promises much, with its multimodal hook, the lure of real-world communication and the proposed independence of its users. To date, however, the potential of educational technology to promote critical thinking that can be transferred to critical writing is under-explored. An opportunity exists to evaluate how argumentation can provide a communicative impetus in a digital learning environment focused on dialogue and collaboration. Theory and practice – based on student voices – can be foregrounded to evaluate the use of scaffolding-type programs, such as digital argument mapping, in the writing classroom.\nAdopting a design-based research methodological approach, data collected from treatment and control groups of Year 9 and 10 students (aged 14-16 years) explored argumentation and digital argument mapping skills and interactions as part of a normal term’s unit of work in two school settings. This research aimed to discover the nature of student disengagement with contemporary practices for the writing of opinion, then explore the results and interpretations of working in an alternative approach. Digital argument mapping was trialled in order to evaluate both its impact on the effectiveness of student writing, and its impact on student engagement with practices dependent on dialogue and collaboration during the writing process.\nSkills in argumentation improved from pre- to post-test writing and both students and teachers reported the usefulness and energy of an approach that focused on the purpose of writing. Most significantly, the use of a digital scaffolding type program challenges several contemporary assumptions about the effectiveness of educational technology in the writing classroom, and for learning more generally. In particular, the creation of a dialogic learning environment around intervention technology used to supplement, not replace, the teacher, was found to lead to more engagement in the writing process and more effective writing. Research findings suggest that a carefully structured teaching program centred on argument can reinvigorate writing by focusing on dialogue and collaboration as part of the planning stage of writing.
[Commonplace book]

Field: Arts and Humanities (Social Sciences)

Commonplace book containing, among other items: 1. Copy of "Majesty in Misery" by King Charles I of England, ca. 1648 -- 2. Epitaphs from tombstones in and near London -- 3. Drydenʼs "Description of a Shipp" and part of his "Conquest of Mexico" -- 4. Moral sentences of Thales -- 5. "Solonʼs Apothegmes by Laerti[us]."
Predictive Computational Modeling of Patient-Specific Cardiac Mechanics

Field: Medicine (Health Sciences)

In this work, a computational model is developed to simulate the cardiac cycle using a patient-specific four-chamber geometry. The enhanced accuracy of efficient boundary conditions modeling the heart-enclosing pericardium is demonstrated through comparison to magnetic resonance imaging. Model evaluation is accelerated significantly using projection-based model order reduction. The reduced order model is used to speed up inverse analysis of cardiac parameters while maintaining accuracy.
The Treatment Outcomes in Children with Medulloblastoma

Field: Medicine (Health Sciences)

Background: Medulloblastoma is the most common central nervous system tumor in childhood. This study aims to evaluate the clinical features, treatments, and outcomes of pediatric patients diagnosed with medulloblastoma Materials and Method:Between 2006 and 2019, the medical records of children with medulloblastoma were reviewed retrospectively. Patients who died after surgery, before chemotherapy or radiotherapy were not included in the survival analysis Results: During the study period, 38 children were diagnosed with medulloblastoma. Twenty-one of the patients were male (55.3%) and 17 were female (44.7%). The ages of the children ranged from 3 months to 17 years (median age 8 years). The ages of five patients were under 3 years (13.1%). The most common complaints were headache (n: 26, 68.4%), imbalance (n: 21, 55.3%), and vomiting (n: 20, 52.6%). The mass sizes ranged between 3 and 6 cm in 32 patients (84.2%). At the time of diagnosis, 5 patients had seeding metastasis (13.1%). The most commonlyused chemotherapy protocol included vincristine, cisplatin, etoposide (60.5%). Five patients died after surgery without any chemotherapy or radiotherapy. Of the 33 patients included in the life analysis, 12 died (36.4%). Follow-up times ranged from 2 months to 14 years (median, 44 months). The overall survival rate was 59.1%. Eight patients had relapsed (24.2%). Late relapse was detected in 3 of the relapsed patients (relapse times were the 91st, 69th, and 72nd months). Conclusions: It is possible to achieve satisfactory treatment results in children with medulloblastoma using international treatment guidelines and recommendations, with an experienced professional team dedicated to pediatric neurooncology.
Ekbom Syndrome or Persistent Delirium with Somatic Symptoms: A Case Report

Field: Medicine (Health Sciences)

Introduction: Delusional infestation (DI), also known as delusional parasitosis or Ekbom's syndrome, is characterized by a patient's fixed belief that one's skin or other parts of the body or one's immediate environment are infested with small living or inanimate pathogens, against all medical evidence for this.The delirium of infestation can however be secondary to a medical pathology, which should be sought.Case report: A 52 year old morrocan women patient who has had paresthesias in her neck and her limbs for two years.She is convinced that she is infested by a parasite that she has been drinking in a glass of water.The evolution has been marked by an accentuation of the symptomatology and recent appearance in a month of an intermittent dysphagia to the solids.The psychiatric assemssment reveals a monothematic delusional syndrome systematized with total adhesion.The patient improved on atypical antipsychotic after eight week of treatment.Conclusion: This case of Ekbom syndrome demonstrates the importance of early management of pruritus or chronic burns and of the search for an underlying organic pathology, a delirium of infestation representing a potential complication.The most important problem is the clinical management of patients because they are often reluctant to engage in a meaningful therapeutic relationship.
Batak Customary Marriage: A Study of the Prohibition of Same-Clan Marriage and Its Relevance in the Contemporary Era

Field: Social Sciences (Social Sciences)

This study discusses Batak customary marriage focusing on the prohibition of same-clan marriage and the practice of same-clan marriage in Batak custom. The main problem studied is the prohibition of intermarriage in Batak society from a fiqh perspective in relation to modern times. This study used a qualitative approach, i.e., a humanistic approach that places humans in research as the main subject in social events. The study was a type of field research, which involves direct observation and examination of facts in the research site, taking the data as primary sources. The findings of this study reveal that the concept of marriage in Batak custom is exogamy, which prohibits marriages between people of the same clan. In Batak custom, people of the same clan are blood relatives or descendants from the father’s line. Batak people who violate this customary law will be subject to customary sanctions. In the current context, the decline in customary values has been influenced by urbanization and higher education, which prioritize modern thinking over traditional one. Education provides certain values for humans, e.g., opening people’s minds, accepting new ideas, and thinking scientifically. Education teaches humans to be able to think objectively, which will give them the ability to assess whether or not their community’s culture can meet the needs of the times. Further, from the perspective of fiqh munakahat, not all family ties are forbidden to marry. Only those related to the provisions of muabbad (permanent prohibition) and ghairul muaabad (temporary prohibition) are prohibited. People from the same clan who have no kinship relationship are still lawful to marry.
Synthesis and characterization of novel Ti-containing mesoporous silicas support

Field: Chemistry (Physical Sciences)

Titanium-containing novel mesoporous silicas have been synthesized at ambient temperature by a sol-gel method using amines with alkyl chains of 10-16 carbon atoms as a templating surfactant. An identical synthesis procedure was followed together with the addition of different amounts of titanium (IV) source in the synthesis gels to obtain its titanium-containing silicate gels. Following this synthesis route, it was possible to prepare materials without forming extrawall TiO2. The transparent gel formed as a precursor resulted in a relatively high titanium incorporation in the silicate framework of up to 0.4% Ti. The characterization results show that most TO4+ are isolated and tetrahedrally incorporated into the framework of the silicate gel. Raman spectra and UV-vis spectra indicated that most Ti atoms were incorporated as isolated Ti sites into the silicate framework, and materials with a higher wt% Ti using relatively more coordination agent to prevent TiO2 forming anatase.
Obstacle Avoidance Strategy and Path Planning of Medical Automated Guided Vehicles Based on the Bionic Characteristics of Antelope Migration

Field: Computer Science (Physical Sciences)

Automated Guided Vehicles (AGVs) face dynamic and static obstacles in the process of transporting patients in medical environments, and they need to avoid these obstacles in real time. This paper proposes a bionic obstacle avoidance strategy based on the adaptive behavior of antelopes, aiming to address this problem. Firstly, the traditional artificial potential field and dynamic window algorithm are improved by using the bionic characteristics of antelope migration. Secondly, the success rate and prediction range of AGV navigation are improved by adding new potential field force points and increasing the window size. Simulation experiments were carried out on a numerical simulation platform, and the verification results showed that the bionic obstacle avoidance strategy proposed in this paper can avoid dynamic and static obstacles at the same time. In the example, the success rate of path planning is increased by 34%, the running time is reduced by 33%, and the average path length is reduced by 1%. The proposed method can help realize the integration of “dynamic and static” avoidance in the process of transporting patients and effectively save time by using AGVs to transport patients. It provides a theoretical basis for realizing obstacle avoidance and rapidly loading AGVs in medical environments.