jimnoneill/paper-to-field-training huggingface dataset:
Development and Implementation of Controller Area Network (CAN) Device Driver for a 32-Bit RISC Architecture based RENESAS Micro-Processor Series with AUTOSAR Software Conformance

Field: Engineering (Physical Sciences)

Device drivers abstract away the technical details and the complexity associated with interfacing a peripheral with the controller network.This in-turn increases the simplicity and reliability of the application software, in-turn reducing the product's time to market.Device drivers provide an interface platform for binding the processor-dependent physical layer and processor independent application layer.So it is corroborated that the device driver must communicate with both the layers, there-by reducing or at the most excluding the processor dependency for application development.The main objective of this work is to provide driver support for Controller Area Network (CAN) communication for a 32-Bit RISC Architecture based Renesas Micro-Processor series, with software conformance for Automotive Open System Architecture (AUTOSAR).AUTOSAR establishes open standards for automotive E/E (Electrics/Electronics) architectures that will provide a basic infrastructure to assist with developing vehicular software, body electronics etc. and management for all application domains like user interfaces, Multi-media etc.This includes the standardization of basic systems functions, scalability to different vehicular platforms, transferability throughout the network and integration from multiple suppliers, software updates and upgrades over the vehicle's lifetime.These features of this particular series of processors provide better interfacing for automotive body applications.The main objective is to provide CAN device driver support to a processor series with AUTOSAR conformance and also includes the support of CAN with flexible data rate or the improved CAN (CAN FD) to improve the bandwidth of the CAN communication network.Practical Extraction and Reporting Language (PERL) will be used for the Link Layer programming.IDEs or tools are used for (Run-Time Environment) RTE configuration, RTE generation and generation of AUTOSAR Basic Software code, which will be used to generate and validate the conformance of the software with AUTOSAR standard.
Plasmin-digest of β-lactoglobulin with antibacterial properties

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The objective of the present study was to identify the antibacterial properties of plasmin digest of β-lactoglobulin (PDβ). After enzymatic treatment, PDβ was fractionated using reversed-phase high-performance liquid chromatography. The antibacterial activity of plasmin, β-lactoglobulin, PDβ, fractionated peptides and nisin as a control was tested against pathogenic (Escherichia coli and Staphylococcus aureus) and probiotic (Lactobacillus casei and Lactobacillus acidophilus) bacteria. Four antibacterial peptides, βL1, βL2, βL3 and βL5, PDβ and nisin as a control revealed antibacterial activity against pathogenic and probiotic bacteria tested. Finally, the identification of the antibacterial peptides was carried out using LC-Mass. Four antibacterial peptides showed molecular masses of 673.116, 819.320, 916.407 and 2410.515 Da, respectively. Two identified antibacterial peptides were βL1 and βL3, which corresponded to residues 78–83 and 83–91 of bovine β-lactoglobulin. The results showed that PDβ as a source of antibacterial peptides can be considered for controlling bacterial contamination.
Comparison Between Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio As Predictors of Mortality on Fournier’s Gangrene Cases

Field: Medicine (Health Sciences)

ABSTRACT Introduction: Fournier’s gangrene (FG) is an infection of the subcutaneous tissue and fascia that progresses quickly and leads to necrosis. It is more prevalent in male patients and immunocompromised individuals, such as those suffering from uncontrolled diabetes. It has a high mortality rate, which makes its early identification and clinical suspicion critical. This study aimed to compare two laboratory parameters, neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), and to predict the mortality of FG in a tertiary care hospital. Methods: In a retrospective study, data was retrieved from medical records for the period from January 2014 to December 2020, of patients diagnosed with FG. Recorded data that is age, sex, comorbidities, mortality, and laboratory results (PLR and NLR) were used to assess determinants of survival. Results: There were 23 (17.04%) nonsurvivors among the 135 subjects studied. The mean age was 50.9 ± 14.9 years and men were 103 (83%) patients. Among the participants, diabetes mellitus was the most frequent comorbidity at 74 (54.81%) patients. NLR ≥8 was statistically significant (P = 0.013) for identifying mortality, while PLR >140 was not. In multivariate analysis, NLR ≥8 was found to be a reliable predictor of the FG mortality rate (adjusted odds ratio 12.062, confidence interval 95% 2.115–68.778, P = 0.005). Conclusion: NLR had prognosis predictive value for FG, whereas PLR did not.
Adjuvant chemoradiotherapy for gastric adenocarcinoma: Kaiser institutional experience with INT 0116

Field: Medicine (Health Sciences)

14114 Background: The standard of care for resectable gastric or gastroesophageal adenocarcinoma is total or partial gastrectomy followed by adjuvant chemoradiotherapy as defined by the Intergroup 0116 study. We have reviewed our institutional experience with this regimen in hopes of defining patient subsets which are most likely to benefit, as well as those who are least likely to benefit, such that alternative therapies may be recommended. Methods: A retrospective review was conducted for 38 consecutive patients treated for gastric or gastroesophageal adenocarcinoma with total or partial gastrectomy followed by chemoradiotherapy. Chemotherapy was with 5-FU 425 mg/m 2 /day and Leukovorin 20 mg/m 2 . Radiotherapy was with 45 Gy in 25 fx delivered through AP-PA fields or a 3-field technique, at the discretion of the treating physician. Results: The median patient age is 55 years old. The median follow-up is 29 months. There were 14 D0 resections, 21 D1 resections, and 3 D2 resections. The number of patients with N0, N1, N2, and N3 disease are respectively 4, 20, 11, 3. One patient did not complete treatment due to disease progression. There were positive margins in 8 patients. Four patients developed fatal treatment-related complications. Median overall survival for patients with positive margins is 19 months and for negative margins is 34 months. Median overall survival for N0/N1 patients is 36 months and for N2/N3 patients is 22 months. Eighteen patients recurred at a median of 14 months - 5 locally, 9 regionally in the abdomen, and 4 distantly. Death occurred in 16/18 recurrences. Conclusions: The overall survival of patients in this study is consistent with previously-reported data. The adequacy of surgical resection is relevant as it affects nodal staging. Positive margin status and advanced nodal involvement are predictors for poor outcomes, indicating that alternative therapies may be more appropriate for these patients given the potential toxicity of the current recommended treatments. No significant financial relationships to disclose.
Gap-junction-mediated Communication in Human Periodontal Ligament Cells

Field: Dentistry (Health Sciences)

Periodontal tissue homeostasis depends on a complex cellular network that conveys cell-cell communication. Gap junctions (GJs), one of the intercellular communication systems, are found between adjacent human periodontal ligament (hPDL) cells; however, the functional GJ coupling between hPDL cells has not yet been elucidated. In this study, we investigated functional gap-junction-mediated intercellular communication in isolated primary hPDL cells. SEM images indicated that the cells were in contact with each other via dendritic processes, and also showed high anti-connexin43 (Cx43) immunoreactivity on these processes. Gap-junctional intercellular communication (GJIC) among hPDL cells was assessed by fluorescence recovery after a photobleaching (FRAP) analysis, which exhibited dye coupling between hPDL cells, and was remarkably down-regulated when the cells were treated with a GJ blocker. Additionally, we examined GJs under hypoxic stress. The fluorescence recovery and expression levels of Cx43 decreased time-dependently under the hypoxic condition. Exposure to GJ inhibitor or hypoxia increased RANKL expression, and decreased OPG expression. This study shows that GJIC is responsible for hPDL cells and that its activity is reduced under hypoxia. This is consistent with the possible role of hPDL cells in regulating the biochemical reactions in response to changes in the hypoxic environment.
UNILATERAL PULMONARY FIBROSIS ASSOCIATED WITH RHEUMATOID ARTHRITIS

Field: Medicine (Health Sciences)

Unilateral pulmonary involvement presents wide differential diagnoses, with neoplasia, fungal, viral and bacterial infections, hemorrhage, thromboembolic events and fibrosis.Interstitial lung disease is rare and mostly related to ipsilateral vascular involvement and gastroesophageal reflux, but it is also reported in association with connective tissue diseases, such as systemic sclerosis and rheumatoid arthritis. CASE REPORTFemale patient, 53 years old, with rheumatoid arthritis for 3 years, rheumatoid factor in high titers, using methotrexate 7.5 mg/week, hydroxychloroquine 400 mg/day and prednisone 5 mg/day, developed dry cough after one month of evolution, with progressive worsening, in addition to relapse of polyarthritis, night sweats, fever, hyporexia and weight loss of 3.5 kg in the period.Discarded hypothesis of COVID-19.She used several broad-spectrum antibiotics, maintained polyarthritis despite the increase in prednisone and methotrexate, cough and reduced oxygen saturation, but without dyspnea.Chest X-ray showed diffuse reticular opacity throughout the left hemithorax.He performed a molecular test for tuberculosis, bronchoalveolar lavage with culture and research for fungi and AFB, all negative.Transbronchial biopsy showed a mild and nonspecific chronic inflammatory process.Submitted to chest tomography: severe fibrocystic lung disease in the left lung, volumetric reduction of the hemithorax on this side and signs of pulmonary hyperinflation, characterizing nonspecific interstitial lung disease (NIBP) of unilateral involvement.The patient was treated with prednisone 1 mg/kg, with an excellent response.Opt for maintenance treatment with rituximab. CONCLUSIONUnilateral interstitial lung disease is rare and its diagnosis can be exhaustive due to the great diversity of differential diagnoses.Treatment at early stages presents greater chances of response in relation to recovery of lung function, justifying further investigation in cases of suspicion.
Graduate Employability, ‘Soft Skills’ Versus ‘Hard’ Business Knowledge: A European Study

Field: Business, Management and Accounting (Social Sciences)

There is a growing awareness in the UK and mainland Europe of the importance of higher education to the development of a knowledge‐based economy. European universities are increasingly required to produce highly mobile graduates able to respond to the ever‐changing needs of the contemporary workplace. Following the Bologna Declaration (1999), higher education across Europe has expanded rapidly. This has resulted in questions being raised about the quality of the graduate labour market and the ability of graduates to meet the needs of employers. This paper analyses graduate and employer perspectives of graduate employability in four European countries (UK, Austria, Slovenia and Romania). In doing so it adds to current debates in this area.
Cyclodextrin/cellulose hydrogel with gallic acid to prevent wound infection

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Cyclodextrin-based hydrogels have been described as suitable for the controlled-release of bioactive molecules to be used as wound dressing. These materials have major advantages, since they gather the hydrogel properties (high degree of swelling and easy manipulation) and the encapsulation ability of cyclodextrins. β-cyclodextrin (β) or hydroxypropyl-β-cyclodextrin (HPβ) was cross-linked (1,4-butanediol diglycidyl ether) with hydroxypropyl methylcellulose under mild conditions. The hydrogels were chemically characterized by swelling degree, FTIR, DSC and contact angle. The gallic acid loading and release was also analysed, as well the antibacterial activity and cytotoxicity of the polymeric networks. The hydrogels obtained were firm and transparent, with good swelling ability. The gel-HPβ had a surface more hydrophilic when compared with the gel-β. Nevertheless, both hydrogels were capable to incorporate gallic acid and sustain the release for 48 h. The antibacterial activity of gallic acid was maintained after its adsorption within the polymeric matrix, as well as, gallic acid effect on fibroblast proliferation. Therefore, gel-β and gel-HPβ conjugated with gallic acid were shown to be a viable option for antibacterial wound dressing.
Following polymerization kinetics of multifunctional acrylates in real time by fluorescence probe methodology

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFollowing polymerization kinetics of multifunctional acrylates in real time by fluorescence probe methodologyJerzy Paczkowski and D. C. NeckersCite this: Macromolecules 1992, 25, 2, 548–553Publication Date (Print):January 1, 1992Publication History Published online1 May 2002Published inissue 1 January 1992https://pubs.acs.org/doi/10.1021/ma00028a009https://doi.org/10.1021/ma00028a009research-articleACS PublicationsRequest reuse permissionsArticle Views248Altmetric-Citations57LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
THE STRUCTURE(S) OF PARTICLE VERBS

Field: Arts and Humanities (Social Sciences)

This paper argues that particle verb combinations do not display a uniform structure but are represented either as a small clause structure or a complex V’-structure. The central claim is that particle verb combinations fall into two classes semantically— transparent vs. idiomatic particle verb combinations—and that this interpretive difference is reflected in the syntactic structure of particle verb combinations. It is argued that transparent particle verb combinations involve a small clause structure whereas idiomatic particle verb combinations involve a complex V’-structure. The arguments for different structures come from a number of syntactic and semantic properties (in particular, thematic properties of the two kinds of particle verb combinations, predication contexts, topicalization, verb second, and verb (projection) raising contexts) that consistently differentiate between transparent and idiomatic particle verb combinations. The analysis proposed does not only bear on the structure of particle verb combinations but also has consequences for the theoretical status of PF-movement.
The role of L3T4-positive T lymphocytes in the generation of anti-tumor immunity in the mouse.

Field: Immunology and Microbiology (Life Sciences)

The role of L3T4-positive lymphocytes in the generation of anti-tumor immunity against syngeneic murine plasmacytoma was investigated. The induction of in vitro primary and secondary cytotoxic T lymphocytes against MOPC-104E plasmacytoma of BALB/c origin was completely inhibited by the addition of monoclonal anti-L3T4 antibody (GK1.5) during the culture period. The possible participation of L3T4-positive lymphocytes in the induction of cytotoxic T lymphocytes was confirmed by the pretreatment of non-immune or immune splenocytes with GK 1.5 plus complement followed by in vitro stimulation with the tumor. The treatment abrogated the ability to generate killer T cell activity. Because the effector killer T lymphocytes were not affected by GK1.5 plus complement treatment, the results strongly suggest that the L3T4-positive lymphocytes might be acting as helper cells for the generation of killer T lymphocytes. The in vivo effect of GK1.5 on anti-tumor immunity was then investigated. Tumor cell growth in mice which received GK1.5 injections was significantly accelerated and the mean survival time of the mice was shorter than that in control groups. On the other hand, mice with established anti-tumor immunity produced by hyperimmunization of tumor cells were affected differently from non-immune mice, showing 50% tumor incidence on day 30 after viable tumor challenge. The present study supports the contention that the L3T4-positive T lymphocytes, probably helper T cells, play a crucial role in the establishment of anti-tumor immunity.
Study on Credit Evaluation Model and Algorithm for C2C E-Commerce

Field: Computer Science (Physical Sciences)

The reputation problem is one of the main bottleneck problems for e-commerce. To a certain extent, the credit evaluation systems provided by C2C e-commerce websites guarantee the safety of transactions on Internet, and promote people's online shopping wishes. This paper first introduces existing credit evaluation model for C2C e-commerce, and analyzes the major problems in it. Then an improved credit evaluation model for C2C e-commerce is created. Based on the improved model, a new weighted rating algorithm is proposed to reflect the influence of evaluation-provider's credit and the amount of a transaction on the change of the evaluation-receiver's credit. And a new credit updating algorithm is described. The new credit evaluation model is validated using synthetic data.
An Epidemiological Review of Common Cancers in Iran; A Review Article

Field: Medicine (Health Sciences)

Cancer is a critical health threat in the world. It has an ongoing increasing trend.The aim of this study was to describe the trend, most common types of cancer and the gender ratio of cancer in Iran and its provinces. We searched PubMed, Google Scholar, Scopus, and Science directs from 2000 to 2017 using Keywords including “Cancer”, “Neoplasms”, “Malignancy”, “Tumor”, “Incidence”, “Epidemiology”, and “Iran”.The most common cancers of Iranian men were skin, stomach, bladder, prostate and colorectal cancers, respectively. The most common cancers of Iranian women were breast, skin, colorectal, stomach, and esophagus cancers, respectively. Cancer has an increasing trend in Iran. Cancer has more burden in the Northern and Northwest provinces of Iran. There was a notable diversity between the occurrences of different types of cancer between different provinces of Iran. Men were more predisposed to cancer. Iran experienced an increasing trend of cancer, like other countries. Different provinces of Iran experienced different patterns. The quality of cancer registry was different, also in many provinces, there were no strong epidemiological studies about cancer. The prevalence of some risk factors was differed in provinces.
Impacts of Managerial Characteristics on the Export Performance of Small and Medium-sized Firms: Review and Implications

Field: Business, Management and Accounting (Social Sciences)

Previous research on export performance has been criticized for being a mosaic of autonomous endeavors and for a lack of theoretical development. Building upon extant models of export performance, a review and analysis of research on impacts of managerial characteristics on the export performance is developed and theoretical explanations are put forward. It is suggested that a multi-theory approach to explaining export performance is viable. Managerial behavior and perceptions for the SMEs from the review and synthesis of the literature are discussed.
Homocytotropic Antibody

Field: Immunology and Microbiology (Life Sciences)

The primary objective of this “Glossary of Terms Used in Immunotoxicology” is to give clear definitions for those who contribute to studies relevant to immunotoxicology but are not themselves immunologists. This applies especially to chemists who need to understand the literature of immunology without recourse to a multiplicity of other glossaries or dictionaries. The glossary includes terms related to basic and clinical immunology insofar as they are necessary for a self-contained document, and particularly terms related to diagnosing, measuring, and understanding effects of substances on the immune system. The glossary consists of about 1200 terms as primary alphabetical entries, and Annexes of common abbreviations, examples of chemicals with known effects on the immune system, autoantibodies in autoimmune disease, and therapeutic agents used in autoimmune disease and cancer. The authors hope that among the groups who will find this glossary helpful, in addition to chemists, are toxicologists, pharmacologists, medical practitioners, risk assessors, and regulatory authorities. In particular, it should facilitate the worldwide use of chemistry in relation to occupational and environmental risk assessment.
School of Nursing, Amachara Abia State 2024/2025 Admission Form Is Out☎ 07037919584. The Management of the school hereby inform the general public on the sales of the general Nursing Admission form into the School of Nursing and also the sales of two (2) years Post Basic Nursing Program contact the school Admin. DR. (MRS.) Helen on ☎07037919584 for more details on how to purchase the form and register online.

Field: Nursing (Health Sciences)

&lt;p&gt;School of Nursing, Amachara Abia State 2024/2025 Admission Form Is Out☎️ 07037919584. The Management of the school hereby inform the general public on the sales of the general Nursing Admission form into the School of Nursing and also the sales of two (2) years Post Basic Nursing Program contact the school Admin. DR. (MRS.) Helen on ☎️07037919584 for more details on how to purchase the form and register online.&lt;/p&gt;
TPC Program Snapshots: Developing Curricula and Addressing Challenges

Field: Arts and Humanities (Social Sciences)

Abstract This article reports results from a survey of US technical and professional communication undergraduate programs concerning core concepts emphasized and most commonly taught procedures, skills, and tools. Snapshot views of current programs are derived from the results, and the developmental processes and directions of four new programs are described in more detail. The article concludes with challenges for programs to maintain humanistic concerns while also providing effective professional and technical preparation.