Intravenous Gammaglobulin, Thrombocytopenia, and the Acquired Immunodeficiency Syndrome

Field: Medicine (Health Sciences)

Letters and Corrections1 September 1985Intravenous Gammaglobulin, Thrombocytopenia, and the Acquired Immunodeficiency SyndromeJ.F. DELFRAISSY, M.D., G. TERTIAN, M.D., M. DREYFUS, G. TCHERNIAJ.F. DELFRAISSY, M.D.Search for more papers by this author, G. TERTIAN, M.D.Search for more papers by this author, M. DREYFUSSearch for more papers by this author, G. TCHERNIASearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-103-3-478_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: Recently, Mintzer and coworkers (1) reported the cases of three patients with immune thrombocytopenia, Kaposi's sarcoma, and the acquired immunodeficiency syndrome. Two of these patients were treated with high-dose intravenous gammaglobulin without benefit. We report the cases of two patients with thrombocytopenia associated with the syndrome who had a dramatic increase in platelet counts after such treatment.Patient 1:A 29-year-old white homosexual man had had thrombocytopenia (platelet count, < 30 X 109/L) for more than a year. His platelet-associated IgG level was significantly elevated, the lymphocyte T4/T8 ratio was low (0.40), and a serologic test for...References1. MINTZERREALJOVINOKROWN DFLS. Treatment of Kaposi's sarcoma and thrombocytopenia with vincristine in patients with the acquired immunodeficiency syndrome. Ann Intern Med. 1985;102:200-2. LinkGoogle Scholar2. WALSHNARDIKARPATKIN CMS. On the mechanism of thrombocytopenic purpura in sexually active homosexual men. N Engl J Med. 1984;311:635-9. CrossrefMedlineGoogle Scholar3. ZEITLHUBERHASCHKEPÜSPÖKLECHNERKNAPPIMBACH UFRKWP. Hemophilia and thrombocytopenia in a patient with impaired cellular immunity: a case report. Blut. 1984;48:393-5. CrossrefMedlineGoogle Scholar4. LAURIANDREYFUSLAMBERTCOURTECUISSEODIEVRETCHERNIA YMTVMG. Purpura thrombopenique chez deux hémophiles. Nouv Rev Fr Hematol. 1983;25:211. Google Scholar5. DELFRAISSYTCHERNIALAURIANWALLONGALANAUD JGYCP. Suppressor cell function after intravenous gammaglobulin treatment in chronic idiopathic thrombocytopenic purpura. Br J Haematol. 1985;60:315-22. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Hôpital Antoine Béclère 92140 Clamart France PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byUsefulness of a low‐dose intravenous immunoglobulin regimen for the treatment of thrombocytopenia associated with AIDSThrombocytopenia in pregnant women infected with human immunodeficiency virus: Maternal and neonatal outcomeDapsone for thrombocytopenic purpura related to human immunodeficiency virus infectionDapsone for thrombocytopenic purpura related to human immunodeficiency virus infectionReview on Therapeutic Options in HIV Associated Thrombocytopenia with Emphasis on I.V. Immunoglobulin TreatmentThe treatment of HIV associated thrombocytopenia in haemophiliacsReport of the symposium on the use of intravenous gammaglobulin in adults infected with the human immunodeficiency virusHuman Immunodeficiency Virus-Associated Thrombocytopenia in InfantsIntravenous ImmunoglobulinHuman immunodeficiency virus-associated autoimmune thrombocytopenic purpura: A reviewClinical use of intravenous immunoglobulin in blood disordersImmunoglobulin Preparations for HIV-Infected PatientsHaematological abnormalities in human immunodeficiency virus (HIV) disease.Isolated thrombocytopenia in patients infected with HIV: Treatment with intravenous gammaglobulinThrombocytopaenia as the Presenting Feature of Persistent Generalised Lymphadenopathy (PGL) in a One Year OldUse of intravenous gamma globulin in children and adolescents with idiopathic thrombocytopenic purpura and other immune thrombocytopeniasThrombocytopenia in a bisexual adolescent male with a history of intravenous drug useResponse to therapy in 37 patients with HIV-related thrombocytopenic purpuraThrombocytopaenia as the Presenting Feature of Persistent Generalised Lymphadenopathy (PGL) in a One Year OldWorkshop on Immunoglobulin Therapy of Lymphoproliferative Syndromes, Mainly AIDS-Related Complex, and AIDSUse of intravenous normal immunoglobulin in high doses as a possible safer alternative to oral steroids in managing HIV associated immune thrombocytopenic purpuraImmune Thrombocytopenia Gammaglobulin, and Seropositivity to the Human T-Lymphotropic Virus Type IIIYVES LAURIAN, M.D., PHILIPPE LE BRAS, M.D., AXEL ELLRODT, M.D., PATRICK ALVIN, M.D.Intravenous Immunoglobulins: Pharmacological Aspects and Therapeutic Use 1 September 1985Volume 103, Issue 3Page: 478-479KeywordsAIDSHomosexualsIdiopathic thrombocytopenic purpuraKaposi sarcomaLymphocytesPatientsPlatelets ePublished: 1 December 2008 Issue Published: 1 September 1985 PDF downloadLoading ...