jimnoneill/paper-to-field-training huggingface dataset:
Assessment of topical bakuchiol and retinol for facial photoageing

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Bakuchiol is found mainly in the seeds of the Indian plant Psoralea corylifolia (babchi) and has recently been shown to have a number of antioxidant and anti‐inflammatory properties. The goal of this study, by researchers from universities in California, Michigan, Florida and Pennsylvania in the US, was to compare the efficacy and side effects of bakuchiol with the commonly‐used anti‐ageing ingredient retinol. 44 volunteers were asked to apply either bakuchiol 0.5% cream twice daily, or retinol 0.5% cream daily, to facial skin for 12 weeks. Retinol 0.5% has previously been shown to be effective at preventing and addressing signs of skin ageing but can have side effects including stinging, scaling and redness. A facial photograph and analytical system was used to take and analyse high‐resolution photographs of patients at 0, 4, 8 and 12 weeks of the study. Patients also answered questions about side‐effects. During study visits, a dermatologist graded pigmentation (skin colouring) and redness. To avoid bias, this dermatologist was not made aware of which treatment each participant was using. The study found that bakuchiol and retinol both significantly decreased wrinkle surface area and hyperpigmentation, with no statistical difference between the two compounds. However, the retinol users reported more skin scaling and stinging. The results were most marked after the full 12 weeks, with a 20 percent reduction in wrinkle severity. 59 percent of the participants in the bakuchiol group showed improvement in their hyperpigmentation at week 12, compared to 44 percent of those in the retinol group. The improvements related both to the intensity of the colour and to the size of the area affected. The findings of this study are promising for bakuchiol as an effective anti‐ageing treatment with minimal side effects, however this would need to be confirmed in larger studies.
AI Driven Talent Acquisition: Integrating Agile and Lean Six Sigma for Process Optimization and Candidate Experience

Field: Business, Management and Accounting (Social Sciences)

The recruitment landscape is changing, as Agile project management, Lean Six Sigma, and Artificial Intelligence (AI) are integrated together. This paper examines how the integration of these three methodologies enhances talent acquisition efficiency, reduces waste, and brings recruitment processes into line with organizational objectives. Agile project management helps create adaptability and collaboration; Lean Six Sigma reduces process inefficiencies; and AI automates routine tasks and provides data-driven insights. The descriptive and analytical research design used was for gathering data from 250 candidates and 100 interviewers by applying purposive sampling, and analyzed through statistical tools. Results indicated significant decreases in recruitment cost, time-to-hire, and candidate waiting times that ensured enhanced candidate satisfaction and better fit to the organizational objectives. This research highlights the importance of combining Agile, Lean Six Sigma, and AI in creating efficient, inclusive, and candidate-centric recruitment processes, offering a framework for organizations to achieve their talent acquisition goals in a dynamic business environment.
The History of the Greek Patriarchate of Jerusalem as Reflected in Codex Patriarchicus No. 428, 1517–1805

Field: Arts and Humanities (Social Sciences)

Between 1891 and 1898 the indefatigable Greek archivist A. Papa-dopoulos-Kerameus published in five volumes the , The Analects of Jerusalemite Gleanings , in which he edited a large number of texts and short listings of documents dealing specifically with the history of the Greek patriarchate of Jerusalem and more generally with the broader historical frame of reference. Despite the richness of the documentation which his publications revealed the scholarly world has taken little notice of this rich source of materials for the history of the Jerusalem patriarchate as well as for the details of Ottoman administration of the region. The present state and disposition of the manuscript collections of the patriarchate are not known to me and in contrast to the collections of the Greek patriarchate of Alexandria and of Mount Sinai I am not aware of any detailed program of exploitation and systematic description of this collection.
Curtailment and Stochastic Curtailment to Shorten the CES-D

Field: Psychology (Social Sciences)

The Center for Epidemiologic Studies–Depression (CES-D) scale is a well-known self-report instrument that is used to measure depressive symptomatology. Respondents who take the full-length version of the CES-D are administered a total of 20 items. This article investigates the use of curtailment and stochastic curtailment (SC), two sequential analysis methods that have recently been proposed for health questionnaires, to reduce the respondent burden associated with taking the CES-D. A post hoc simulation based on 1,392 adolescents’ responses to the CES-D was used to compare these methods with a previously proposed computerized adaptive testing (CAT) approach. Curtailment lowered average test lengths by as much as 22% while always matching the classification decision of the full-length CES-D. SC and CAT achieved further reductions in average test length, with SC’s classifications exhibiting more concordance with the full-length CES-D than do CAT’s. Advantages and disadvantages of each method are discussed.
A semi‐automated procedure for aiding the diagnosis of cervical neoplasms based on the measurement of acid‐labile dna in exfoliated cells

Field: Medicine (Health Sciences)

Abstract Measurements of acid‐labile fractions of DNA in cells exfoliated from cervical neoplasms (invasive squamous‐cell carcinomas) using Feulgen techniques have shown elevated values in both abnormal and cytologically normal cell nuclei. These increased values occur early in the hydrolysis profiles before the Feulgen hydrolysis optimum for the cell nuclei of normal patients has been attained. They are of sufficient magnitude to enable a microcomputer programmed in BASIC to distinguish between normal and abnormal cells, even when the latter are of cytologically normal appearance. By semi‐automating the measurement procedure using a microcomputer interfaced with a Vickers M86 microdensitometer, the assessment of acid‐labile DNA in cell nuclei is proposed as a useful aid to the existing cytological diagnosis of cervical neoplasms.
Temporal Dialogues: Collaborative Photographic Re-enactments as a Form of Cultural Critique

Field: Arts and Humanities (Social Sciences)

This article explores the use of photographs and photographic methods in qualitative anthropological analysis. With a point of departure in the W. Baldwin Spencer and Francis J. Gillen collection of photographs, I discuss archive mining, photo repatriation, and collaborative photographic re-enactments of the original material during fieldwork in Central Australia. The combination of these methods through an interventionist approach generates a stimulating environment for cross-cultural and cross-temporal dialogue, centered on productive collaborations that invite cultural critique through juxtaposition and defamiliarization.
THE NATIONAL REVOLUTIONARY PARTY AND THE RELIGIOUS QUESTION

Field: Social Sciences (Social Sciences)

The National Revolutionary Party was founded in 1929 to win elections and to resolve conflicts between different political groups after the Mexican Revolution. But it was also created in order to face the opposition of the Catholic hierarchy to the Constitution of 1917 and the measures that the revolutionary governments had established to “defanatize” the Mexican people and to limit the social influence and therefore the political power of the Catholic Church. In the past decades nevertheless, the PRI has evolved from initial anti-clerical and even antireligious positions towards more respectful positions of religious freedom, in line with the logic of a State that considers itself to be plural and respectful of differences. On the other hand, party authorities do not always respect their liberal and revolutionary tradition, the secularism of the state and the principle of separation that guarantees the moral autonomy of individuals against corporations. At times, the search for legitimacy generates political dependence and eventually leads to the imposition of the creeds and dogmas of majorities with respect to minorities of all kinds consequently eliminating the free will of broad sectors of the population that do not share those principles and expect the protection and guarantee of their rights by the secular State.
Multi-well DAS Observations for Hydraulic Fracture Monitoring

Field: Earth and Planetary Sciences (Physical Sciences)

Summary Multi-well fiber-optic DAS installation are becoming increasingly more common for hydraulic fracture monitoring applications when hydraulically treating multiple stacked layers per pad. In contrast to earlier single-well fiber recordings, these multi-well recordings allow us to track low frequency strain fronts between various treatment well. We also show that with a suitable multi-well fiber geometry microseismic detection is improved and accurate 3D event location determination is possible, enabling further detailed analysis of fracturing efficiency.
The new fossil lacewings of Grammolingiidae (Neuroptera) from the Jurassic of Central Asia and Mongolia, with notes on biogeography of the family

Field: Agricultural and Biological Sciences (Life Sciences)

Khramov, Alexander V. (2012): The new fossil lacewings of Grammolingiidae (Neuroptera) from the Jurassic of Central Asia and Mongolia, with notes on biogeography of the family. Zootaxa 3478: 297-308, DOI: 10.5281/zenodo.212283
A Comprehensive Comparison Between Discrete Fracture Network and Generalized Anisotropic Material Behavior for Modeling Jointed Rock Mass

Field: Earth and Planetary Sciences (Physical Sciences)

ABSTRACT: Rock masses are blocky assemblages formed by networks of natural discontinuities (fractures), such as joints, foliations, shear zones or faults, formed by geological activities. To accurately predict the mechanical behavior of rock mass, it is essential to consider these fractures. The complex interaction between intact rock and those fractures coupled with man-made excavation imposes critical limitations to predict rock mass behavior solely via kinematic or analytical methods. In this context, numerical modeling approach fills the need for a powerful tool that can provide geotechnical engineers with sophisticated solutions to complex rock mechanics problems. This paper demonstrates different approaches to model joint sets in 3D Finite Element Method (FEM) to model discontinuities in jointed open pit mine. They include the explicit representation of discontinuities using Discrete Fracture Network (DFN) and incorporation of a special constitutive model that considers anisotropic material behavior to the solid elements that implicitly account for the presence of joint sets. The investigation presents findings from simulations involving models with single and multiple joint sets. Notably, the focus is given to validating the use of DFN and the benefits for slope stability assessment. The obtained results showed high levels of agreement between the two modeling approaches, underscoring the efficacy of DFN in replicating the complex behavior of geological structures. These insights contribute to the enhancement of the rock slope designs with significant implications for the safety and profitability of mining operations. 1. INTRODUCTION In open pit mining, the primary objective is to maintain the structural integrity of the slope surface and prevent/mitigate any potential failures. Achieving a cost-effective yet stable design for open-pit mines requires a comprehensive grasp of lithology, rock mass characteristics, and structural geology. Thus, conducting a robust slope stability assessment for open pit excavations is of utmost importance to ensure the safety of mining operations. The presence of geological structures (also termed as natural discontinuities) such as joints, foliations, and faults within rock mass introduces complexities in stress distribution and stability, which are unique to the geological history of different regions. Therefore, a thorough consideration of natural discontinuities is imperative in geomechanical analyses and design exercises to gain accurate prediction of rock mass behavior. They play a pivotal role in controlling the driving failure mechanism to slope instability. With respect to the distribution, surface condition, and orientations of discontinuities, the mechanical response of rock mass should vary extensively.
Combining physics-based and machine learning methods to accelerate innovation in sustainable transportation and beyond: a control perspective

Field: Engineering (Physical Sciences)

Lithium-ion batteries are playing a key role in the sustainable energy transition. To fully exploit the potential of this technology, a variety of modeling, estimation, and prediction problems need to be addressed to enhance its design and optimize its utilization. Batteries are complex electrochemical systems whose behavior drastically changes as a function of aging, temperature, C-rate, and state of charge, posing unique modeling and control research questions. In this tutorial paper, we provide insights into three battery modeling methodologies, namely first principle, machine learning, and hybrid modeling. Each approach has its own strengths and weaknesses, and by means of three case studies we describe main characteristics and challenges of each of the three methods.
MANAJEMEN KEPALA SEKOLAH DALAM MENINGKATKAN KINERJA GURU DI MA KARYA BAKTI SUKASARI

Field: Social Sciences (Social Sciences)

This research aims to describe the management of school principals in improving teacher performance at MA Karya Bakti Sukasari. This can be seen in the implementation of school principal management in improving teacher performance, which includes planning, organizing, implementing, and supervising. This research uses a qualitative approach with descriptive research methods. The data sources used in this research used interview data collection techniques and documentation studies. Research data analysis was carried out through the following steps: (1) data reduction, (2) data presentation, (3) drawing conclusions. The results of the research show that: (1) The planning carried out by the head of MA Karya Bakti is based on the vision, mission, school goals, needs (need assessment) which are formulated in the school program created at the beginning of each new school year which is agreed upon with the teachers through meetings teachers' council; (2) The organization has been carried out by the school principal with the division of tasks according to the expertise of the teachers through new school year meetings; (3) The implementation of the school principal as a manager can be seen in the implementation of all programs that have been designed. This program is in accordance with the school program created at the beginning of each new school year as agreed with the teachers; and (4) Supervision carried out by the school principal to improve teacher performance, namely by conducting supervision. Supervision is carried out situationally, usually starting with student problems and then evaluating the teaching methods used by the teacher in class
Development of the voluntary health insurance market in Ukraine

Field: Social Sciences (Social Sciences)

This paper is aimed to study the development trends of the domestic voluntary health insurance market. The authors analyzed the current state of the domestic voluntary health insurance market by its types. In the study framework, the main tendencies were determined, while the relative ratios of voluntary health insurance market functioning were calculated. Health insurance has a great potential to be a promising source of additional funding for medicine in Ukraine. However, the systematization of scientific sources indicated that unresolved issues of further development of health insurance and the search for effective external funding sources for medicine in Ukraine, one of which may be the market of voluntary health insurance. This research’s urgency consists of insufficient healthcare budgetary funding and low healthcare quality, provoking external funding sources’ growth in national healthcare facilities such as voluntary health insurance. The study of the features of the voluntary health insurance market development was carried out in the following logical sequence: determining the relevance of the research topic; investigating the scientific background on the research topic; establishing the methodological basis; analyzing the indicators of voluntary medical insurance market development; considering the structure of health funding sources in Ukraine and some countries of Eastern Europe. The authors determined a need to develop voluntary health insurance in Ukraine as an external health funding source based on the findings. The conclusions and recommendations were formed. The study involved the methods of deduction and induction, analogy and comparative analysis, graphical method, method of statistical comparison. The research object is the voluntary health insurance market in Ukraine. The research period is 2012-2020. The obtained results indicated that the voluntary health insurance market is undoubtedly an essential component of the Ukrainian insurance market. The authors noted that it is an effective additional way for actual funding the social needs in medicine. Therefore, it calls for further in-depth study and more attention from the population. The results of this study could be helpful for scientists, health and insurance professionals.
Exploring Fit in an mHealth Effectiveness-Implementation Trial: A Qualitative Study (Preprint)

Field: Health Professions (Health Sciences)

BACKGROUND

Implementation frameworks like the EPIS model emphasize the importance of the “fit” between an intervention and its context, which includes the needs of its target population, as well as the culture, resources, and capabilities of the implementing organization. Even though lack of fit is a major barrier to implementation, fit has not often been a focus of implementation research.

OBJECTIVE

This paper uses fit as a lens to examine the implementation of Tula, an mHealth app aimed at reducing risky drinking days among individuals meeting the criteria for mild to moderate alcohol use disorder, in a 3-arm (app alone; app plus peer mentoring; app plus health coaching) RCT.

METHODS

Semi-structured interviews with 18 trial participants and 7 Tula implementers were conducted. Trial participants were pulled equally from each arm of the trial, and represented participants who demonstrated both high and low engagement with the application. Implementers consisted of a project manager, 4 peer mentors, and 2 health coaches. Interviews with participants focused on their motivations, opinions, and experiences of the intervention and their perception of their drinking behavior following the intervention, including how their use of the app worked to change that behavior. Interviews with implementers were centered on their roles, theories of change, perceptions of intervention, and areas for improvement. All interviews were analyzed using rapid qualitative analysis with both deductive and inductive components.

RESULTS

We identified areas of both fit and misfit. For example, there was a good fit between implementers’ theories of change and participants’ description of how change occurred. Fit was improved by the versatility of the app, which allowed participants to customize their experiences. Conversely, misfit was noted in the app’s inability to cultivate connection for many participants and a disjunction between the role of peer mentors in the intervention and their broader professional ethos.

CONCLUSIONS

Focusing on fit provides a useful guide to enhance future iterations of the Tula app that lead to better sustainment of the intervention.

CLINICALTRIAL

NCT04011644 (ClinicalTrials.gov). Registered 08 July 2019. Available at: https://clinicaltrials.gov/study/NCT04011644

INTERNATIONAL REGISTERED REPORT

RR2-10.2196/31109
Copy number status of <i>BPY2, DAZ</i> and <i>SRY</i> based on qPCR.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

<p>Copy number of <i>BPY2, DAZ</i> and <i>SRY</i> genes were found to be normal, i.e. 3, 4 and 1, respectively, in all the normal fertile males.</p>
Potential Smoothened Inhibitor from Traditional Chinese Medicine against the Disease of Diabetes, Obesity, and Cancer

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Nowadays, obesity becomes a serious global problem, which can induce a series of diseases such as type 2 diabetes mellitus, cancer, cardiovascular disease, metabolic syndrome, and stoke. For the mechanisms of diseases, the hedgehog signaling pathway plays an important role in body patterning during embryogenesis. For this reason, smoothened homologue (Smo) protein had been indicated as the drug target. In addition, the small-molecule Smo inhibitor had also been used in oncology clinical trials. To improve drug development of TCM compounds, we aim to investigate the potent lead compounds as Smo inhibitor from the TCM compounds in TCM Database@Taiwan. The top three TCM compounds, precatorine, labiatic acid, and 2,2′-[benzene-1,4-diylbis(methanediyloxybenzene-4,1-diyl)]bis(oxoacetic acid), have displayed higher potent binding affinities than the positive control, LY2940680, in the docking simulation. After MD simulations, which can optimize the result of docking simulation and validate the stability of H-bonds between each ligand and Smo protein under dynamic conditions, top three TCM compounds maintain most of interactions with Smo protein, which keep the ligand binding stable in the binding domain. Hence, we propose precatorine, labiatic acid, and 2,2′-[benzene-1,4-diylbis(methanediyloxybenzene-4,1-diyl)]bis(oxoacetic acid) as potential lead compounds for further study in drug development process with the Smo protein.
Representing the Other: Portrayal of Mexicans in Contemporary Hollywood Movies

Field: Arts and Humanities (Social Sciences)

Around the turn of the twenty-first century, the harsh conditions experienced around the Mexican-American border drew the attention of Hollywood to this area. Film producers began to use the topic of the barrier as a “way of ‘narrating the nation’, that is of embodying its features and qualities in a certain place, or image of place,” and narrowed it down into two subtopics: illegal immigration and drug trafficking. The issue of illegal immigration has always served as a significant source of inspiration for filmmakers. A number of movies have dealt with the question of border-crossing, assimilation and smuggling, many of them drawing a parallel between immigration and drug trafficking.