jimnoneill/paper-to-field-training huggingface dataset:
MEASURING CHINESE RURAL SCIENCE TEACHERS’ SELF-PERCEPTION TOWARDS TEACHING COMPETENCIES: INSTRUMENT DEVELOPMENT

Field: Social Sciences (Social Sciences)

The teaching competency of rural teachers is fundamental to providing rural pupils with a high-quality education. Nonetheless, China has not yet established standardized competence criteria for rural science teachers, making it difficult to ascertain the actual competence of the rural teaching force on the front lines. Consequently, this study aimed at accessing Chinese rural science teachers’ teaching competency and exploring rural-urban differences by developing a measurement instrument. Factor analyses confirmed the reliability and validity of this instrument, which consisted of 21 items and four dimensions. In addition, the questionnaire was employed to examine 393 science teachers in China, discovering the significant rural-urban differences in terms of teaching implementation and learning evaluation together with teacher distribution. This study was hoped to promote the building of the teaching competency system and provide references for rural science teachers’ professional development. Keywords: rural teacher, teaching competency, science teacher, factor analysis
Prospective investigation of folic acid supplements before and during early pregnancy and paediatric and adult cancers in the Chinese children and families cohort: a pilot study in a sample of rural and urban families

Field: Medicine (Health Sciences)

Objective To determine the feasibility of long-term prospective follow-up and ascertainment of cancer in offspring and mothers from the 1993–1995 Chinese Community Intervention Program that provided folic acid supplements before and during early pregnancy to reduce neural tube defects. Design Feasibility pilot study for a prospective cohort study. Setting Families residing during 2012–2013 in one rural and one urban county from 21 counties in 3 provinces in China included in the Community Intervention Program campaign. Participants The feasibility study targeted 560 families, including 280 from the rural and 280 from the urban county included in the large original study; about half of mothers in each group had taken and half had not taken folic acid supplements. Intervention The planned new study is observational. Primary and secondary outcome measures Primary: incidence of paediatric cancers in offspring; secondary: other chronic diseases in offspring and chronic diseases in mothers Results Only 3.4% of pilot study families could not be found, 3.9% had moved out of the study area and 8.8% refused to participate. Interviews were completed by 82% of mothers, 79% of fathers and 83% of offspring in the 560 families. Almost all mothers and offspring who were interviewed also participated in anthropometric measurements. We found notable urban–rural differences in sociodemographic and lifestyle characteristics of the parents, but fewer differences among the offspring. In eight catchment area hospitals, we identified a broad range of paediatric cancers diagnosed during 1994–2013, although paediatric brain tumours, lymphomas and rarer cancers were likely under-represented. Conclusions Overall, 20 years after the original Community Intervention Program, the pilot study achieved high levels of follow-up and family member interview participation, and identified substantial numbers of paediatric malignancies during 1994–2013 in catchment area hospitals. Next steps and strategies for overcoming limitations are described.
Noise Suppression Threshold Channel Estimation Method Using RC and SRRC Filters in OFDM Systems

Field: Engineering (Physical Sciences)

Orthogonal frequency division multiplexing (OFDM) has been widely used in modern wireless communication systems. In OFDM system, channel estimation is a key technology to improve the system performance. However, most conventional channel estimation methods cannot suppress the noise effectively, which affects the quality of the final received OFDM signals. To solve this problem, this paper utilizes the raise cosine (RC) filter and square root raise cosine (SRRC) filter to suppress the inter-symbol-interference (ISI) and the noise in OFDM-RC and OFDM-SRRC systems. The proposed method first filters out the noise by using RC filter or SRRC filter, while obtaining the noise standard deviation as the threshold. Then, the impact of noise is further reduced by setting the noise suppression threshold. Simulation results are shown to verify the effectiveness of the OFDM-RC and OFDM-SRRC systems over multipath propagation conditions.
[Letter on the article "Consequences of critical appraisal of medical literature on 2009 national ranking in France"].

Field: Medicine (Health Sciences)

In older studies, a chronic distal symmetric sensory neuropathy was reported as a relatively common manifestation of late Lyme disease in the United States. However, the original papers describing this entity had notable inconsistencies and certain inexplicable findings, such as reports that this condition developed in patients despite prior antibiotic treatment known to be highly effective for other manifestations of Lyme disease. More recent literature suggests that this entity is seen rarely, if at all. A chronic distal symmetric sensory neuropathy as a manifestation of late Lyme disease in North America should be regarded as controversial and in need of rigorous validation studies before acceptance as a documented clinical entity.
Atrial Embolization of a Vena Cava Filter with Dual Fixing System

Field: Medicine (Health Sciences)

Inferior vena caval filters are often seen as a safe and effective means of preventing pulmonary embolism in at-risk patients who have contraindications to pharmacological therapy. Filter migration is a rare event and there is no description in the literature with the Braile dual fixing system filter. This is a report of a case where filter embolization to the right atrium in a 60-year-old male patient led to tricuspid insufficiency, sepsis, and death. We would like to emphasize the “sailing effect” that probably occurred in this case.
DIGITAL MANAGEMENT AS AN INTEGRAL COMPONENT OF THE DIGITAL ECONOMY

Field: Business, Management and Accounting (Social Sciences)

The article considers the changes taking place in the management system of organizations in the transition to the digital economy. The theoretical bases of digital control development are investigated. Distinctive features of digital management in comparison with traditional are defined, influence of digital technologies on economic indicators of activity of the organization is analyzed. The results of the study can be used in the practice and theory of management of the organization to address a wide range of issues related to the implementation of digital technologies in various areas of management. The purpose of the research was to study the features of management in the global digitalization of the economy and identify trends in the further development of digital management. The subject of the study are the changes taking place in the management system of organizations in the digital transformation of the economy. An analysis of the implementation of digital management tools through the use of the necessary technical support and the ability of staff to implement innovative implementation procedures. Elements of digital infrastructure that ensure effective use of digital management tools are studied. The article considers the changes taking place in the management system of organizations in the transition to the digital economy. The theoretical bases of digital control development are investigated. It is shown that on the basis of the traditional management system based on the studied and worked out elements and the outdated theoretical basis, there is a new management model which is based on obligatory use of the software for automation of administrative activity that in turn opens up fundamentally new opportunities for the organization of enterprises in the digitalization of society and the digital economy. The high level of relevance of this issue and the need to implement effective digital management of organizations indicates the need for further research to study this problem. Promising areas of further research in digital management are: forecasting further changes in the digital management system with the development of innovative technologies in Industry 4.0; development of digital management theory in relation to certain industries; development of mechanisms for adaptation of managers and employees of the management staff to the introduction of digital technologies and expansion of the digital space of management; formation of digital competencies of managers in accordance with the strategy of digitalization of enterprises and trends in technology 4.0 Industry.
Input Assistive Keyboards for People with Disabilities: A Survey

Field: Health Professions (Health Sciences)

Any device, equipment or courseware that assists people to work around the limitations caused by their disabilities comes under the category of Assistive Technology. People with certain sort of disabilities using these Assistive Technologies can compensate a boundary caused due to their disability. Certain types of assistive technologies help people with disabilities to achieve their life goals and hence allowing them to be operative in specific fields. Several Assistive Technology devices have helped people with disabilities in acquiring their dream jobs and reducing the external support needed by them for earning a livelihood. In this paper, a survey of commercial and patented one handed input devices that are in practice in the society has been done.
Biological functions of RNA modification patterns that define tumor microenvironment and survival outcomes in testicular germ cell tumors.

Field: Medicine (Health Sciences)

We generated and validated a risk signature related to RNA modification which could accurately predict the relapse risk in TGCT patients. This risk signature was correlated with immune cells infiltration among tumor microenvironments. Furthermore, we screened antitumor drug candidates and evaluated the sensitivity and efficacy of class chemotherapeutic drugs, which could provide reference for clinical drug use.
A modern way to organize and build your TYPO3 Site with Composer and Webpack Encore

Field: Computer Science (Physical Sciences)

The way we are using TYPO3 has constantly been changed in the last 10 years. I will show you, how we use state-of-the-art technologies to optimize and automatize the way of building and deploying our TYPO3 sites. History There were times no source code repository existed and everything was done live on the server. Then we had monolithic repositories in Subversion (do you member?) where each and everything belonging to the site was stored.
A Bibliometric and Content Analysis of Strategy-Based Instruction in Second or Foreign Language Teaching From 2000 to 2021

Field: Arts and Humanities (Social Sciences)

This systematic review aims to identify the research trend and gap of strategy-based instruction research in second or foreign language domain from 2000 to 2021. The study involves both bibliometric and content analysis. To gain an overall understanding of the research on strategy-based instruction, this study employs keywords co-occurrence analysis to analyze data obtained from Web of Science and Scopus. The content analysis coded four themes: learning context, research objects, intervention framework, and indicators. The bibliometric findings offered analytical information on keywords, sources, and regions of selected documents, revealing the latest research focuses. The findings of content analysis further explored each document and provided in-depth data concerning learning contexts and research objects. The content analysis also indicates characteristics of successful SBI design by outlining the contexts and implementations of interventions. The results of this study can be useful resources to researchers intending to conduct research in SBI field, since the study discussed both what has been done (existing research focuses) and what needs to be done (research trends and research gap).
Comparison of 10 enzyme immunoassays for detection of antibody to human immunodeficiency virus type 2 in West African sera

Field: Medicine (Health Sciences)

The efficacies of nine enzyme-linked immunosorbent assays (EIA) for antibody to human immunodeficiency virus type 1 (HIV-1) and one EIA for antibody to HIV-2 in detecting antibody to HIV-2 were studied. The competitive EIAs for antibody to HIV-1 were less sensitive than the indirect EIAs. The overall prevalence of positive results was between 28 and 51% with the competitive EIAs and between 70 and 93% with the indirect EIAs. Most of the EIAs were less sensitive in detecting antibody to HIV-2 in sera from people with acquired immunodeficiency syndrome-like diseases than in sera from symptomless individuals. The results indicate that there is a high degree of cross-reactivity between HIV-1 and HIV-2 by EIA, indicating that serotype specificity must be determined by Western blot (immunoblot) with both sets of viral antigens. The results are relevant for discussing public health strategies, especially the screening of blood donors; competitive EIAs for antibody to HIV-1 are not sensitive enough to be used in areas where HIV-2 is prevalent (West Africa).
www.kjurology.org DOI:10.4111/kju.2010.51.8.525 Urological Oncology Efficacy of Bladder-Preserving Therapy for Patients with T3b, T4a, and T4b Transitional Cell Carcinoma of the Bladder

Field: Medicine (Health Sciences)

Purpose: Radical cystectomy has been the most widely used method in the treatment of bladder cancer, but it is limited by major problems. Therefore, we investigated the results of bladder-preserving treatment in patients with T3b, T4a, and T4b transitional carcinoma of the bladder who underwent transurethral resection of bladder cancer and subsequent administration of chemotherapy. Materials and Methods: Of all patients who were diagnosed with bladder cancer and underwent bladder-preserving treatment between January 2001 and August 2008, 78 patients with at least 12 months of follow-up data were enrolled in this study. All patients received gemcitabine (1,000 mg/m 2) and cisplatin (70 mg/m 2) once per month postoperatively for a total of 6 months and completed a follow-up visit every 3 months. The patient survival rate and prognostic factors (age, tumor size, differentiation, number of lesions, stage, and presence of hydronephrosis) were assessed. The Kaplan-Meier method was used to analyze survival rate, and Cox multiple regression analysis was used for prognostic factors. Results: The mean patient age was 68.32±8.6 years, the mean duration of follow-up
The Impact of the 2012 Spanish Labour Market Reform on Unemployment Inflows and Outflows: a Regression Discontinuity Analysis using Duration Models

Field: Economics, Econometrics and Finance (Social Sciences)

This paper studies the impact of the 2012 Spanish labour market reform on the probability of exiting and entering unemployment using a regression discontinuity approach based on duration models. The 2012 reform modified important aspects of hiring and dismissal procedures in Spain. By doing so, it affected the probability of exiting both unemployment and employment. Comparing labour market performance before and after February 2012 and using a competing risk duration model for the exit from both unemployment and employment, we find that the reform contributed to employment creation in two ways. First, it increased the likelihood of exiting from unemployment to employment by increas-ing the monthly transition to permanent employment from 1.7% to 2.6%, on average, for the first twelve months of unemployment. Second, it reduced the probability of exiting from employment for workers on a temporary contract, particularly at small firms, most likely because the firms were using newly introduced internal flexibility measures to adjust the workforce instead of using external flexibil-ity measures. The direct transition from temporary to permanent positions was also eased by the re-form. Finally, we do not find any significant effect of the reform on the dismissal patterns for perma-nent workers. These findings point to a positive effect of the reform in dampening the widespread segmentation of the Spanish labour market, although the impact is so far small, which means that more effort will be needed to substantially reduce the strong duality of this labour market.
Angelica Polysaccharide and TPO Have a Protective Effect On Hcmv-Induced Apoptosis In Megakaryocytes

Field: Medicine (Health Sciences)

Abstract Human cytomegalovirus (hCMV) infection is often associated with thrombocytopenia. Megakaryocytes may be one of the major sites of hCMV infection, then inducing this cell apoptosis. Angelica Sinensis (Danggui) is an important ingredient of many commonly used herbal Medicine for promoting blood production. Our previous study has showed that the hematopoietic effect of Angelica Sinensis is related to its constituent, angelica polysaccharide (APS) (Yang M et al, J Ethnopharma, 2009). This present study investigated the anti-apoptotic effect of APS and TPO on hCMV-induced apoptosis in megakaryocytes. Human bone marrow mononuclear cells (MNC) or megakaryocytic cell line CHRF-288-11 and hCMV AD169 strain were co-cultured in this study. hCMV significantly inhibited the formation of CFU-MK as shown in three different concentrations of viral infection groups (103, 104 and 105 pfu/ml), compared with blank control and mock control (n=10, P<0.05). hCMV also significantly inhibited the growth of CHRF cells in these three different concentrations after incubation for 3 days, which compared with control group (n=10, P<0.01). hCMV DNA and mRNA were also positively detected in CHRF cells and the cells of CFU-MK with IS-PCR and RT-PCR respectively, while it was negative in blank and mock control groups. We further studied the effect of APS and TPO on CFU-MK formation. Results showed that APS (50 ug/ml) like TPO (50 ng/ml) enhanced hCMV-reduced CFU-MK (P=0.05, n=6). CHRF cells were also analyzed by Annexin V/PI with flow cytometry at day 3 after infection with hCMV AD169. The percentage of apoptotic cells in group of 103 pfu/ml was 19.0 ± 2.0%; The group of 104 pfu/ml was 23.0 ± 1.5%; The group of 105 pfu/ml was 28.0 ± 3.0%. The control group was 2.0 ± 0.5%. The apoptotic cells were confirmed by morphologic observation. In addition, apoptotic signals from megakaryocytic surface, cytoplasma and mitochondria were detected in hCMV infected cells by flow cytometry with Caspase-3 and JC-1 assay. Compared to mock infection control at day 5, Annexin-V positive cells population increased by 58%; active caspase-3 signal increased by 120% in viable cell population; and cell population with damaged mitochondial membrane showed a 5-times increase. Moreover, the anti-apoptotic effect of APS and TPO on CHRF cells was also demonstrated by using Annexin-V assay. Our studies showed that hCMV induces the apoptosis in megakaryocytes via mitochondrial and caspase-3 signaling, and angelica polysaccharide (APS) like TPO has a protective effect on hCMV-induced apoptosis in these cells. Disclosures: No relevant conflicts of interest to declare.
The performance of buffer bow structures against collision

Field: Engineering (Physical Sciences)

In order to prevent a disastrous damage induced by collision accident which might cause cargo oil spill from a struck oil tanker, the double hull system in side hull of oil tanker has been recognized as an effective countermeasures. However, when considering that ocean-going vessels are increasing not only in size but also in speed, the threat of disastrous collision accident should be further mitigated also on the responsibility of striking ships. The concepts of buffer bow have been proposed supposing its installation to fast passenger ships in the late 1960s and to large cargo vessels equipped with bulbous bow in the 1990s. RR76 panel of Shipbuilding Research Association of Japan and Ship Research Institute have started, as a joint work, to study the necessary items for the buffer bow structure since 1998.SRI has conducted a series of crush test using three kinds of simplified scale models of the buffer bow. A simple analysis method has been developed to evaluate the crashworthiness of buffer bow structure and its accuracy has been verified by comparing the results with the test and FEM calculation as well. The paper describes the performance of the buffer bow focusing on the collapse mechanism and the P/δ relation, then demonstrates the effectiveness of the present analysis method.
A tripartite transcriptional module regulates protoderm specification during embryogenesis in Arabidopsis

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Summary Protoderm formation is a crucial step in early embryo patterning in plants, separating the precursors of the epidermis and the inner tissues. Although key regulators such as ARABIDOPSIS THALIANA MERISTEM LAYER1 (ATML1) and PROTODERMAL FACTOR2 (PDF2) have been identified in the model plant Arabidopsis thaliana , the genetic pathways controlling protoderm specification remain largely unexplored. Here, we combined genetic, cytological, and molecular approaches to investigate the regulatory mechanisms of protoderm specification in Arabidopsis thaliana . We report a novel role of the β‐importin KETCH1 in protoderm specification. KETCH1 loss‐of‐function leads to aberrant protoderm cell morphology and absent ATML1 transcription in embryos. We further demonstrate that KETCH1 directly interacts with an RNA Polymerase II (Pol‐II) cofactor JANUS, mediating its nuclear accumulation. Furthermore, JANUS directly interacts with the WUS HOMEOBOX2 (WOX2) protein, which is critical for WOX2‐activated ATML1 expression. Consequently, JANUS , KETCH1 , and WOX2 loss‐of‐function results in similar protoderm defects. Our results identify the tripartite KETCH1/JANUS/WOX2 transcriptional module as a novel regulatory axis in Arabidopsis protoderm specification.
The specific needs of adults who are gifted

Field: Psychology (Social Sciences)

The gifted adult often needs help just as much as the gifted child. Investigation of a small sample of gifted aduits presented some disturbing possibilities which merit investigation. Out of 24 gifted adults, 16 had contemplated suicide and gone so far as to devise a means. Half of these 16 people had made at least one suicide attempt. This article illustrates how the problems of being a gifted child can be taken into adult life.