jimnoneill/paper-to-field-training huggingface dataset:
124-OR: Progressive Loss of Corneal Nerve Fibers and Sensitivity with Duration of Obesity Type 2 Diabetes in Sprague-Dawley Rats: Valid Marker for Peripheral Neuropathy and Treatment

Field: Medicine (Health Sciences)

Purpose: Determine whether density of nerve fibers in the cornea and corneal function are valid markers for early detection and treatment of peripheral neuropathy in rat models of prediabetes and type 2 diabetes. Methods: Rat models for prediabetes and type 2 diabetes were created and longitudinally studied for loss of structure and function of sensory nerves in the cornea and skin as well as nerve conduction velocity and vascular reactivity of epineurial arterioles. Reversibility of neuro and vascular pathology was also examined in these models following chronic obesity or type 2 diabetes after dietary intervention with menhaden oil a natural source of long chain omega-3 polyunsaturated fatty acids. Results and Conclusions: Our longitudinal study demonstrated that vascular and neural dysfunction associated with obesity or type 2 diabetes occur early and are progressive. Decrease in cornea nerve fiber length and function were valid markers of disease in both the prediabetic and diabetic rat models and were more sensitive than decrease in intraepidermal nerve fiber density of the skin and thermal nociception of the hindpaw. Late intervention with menhaden oil reversed both vascular and peripheral damage induced by chronic obesity or type 2 diabetes. These studies provide support for examination of corneal structure and function as an early marker of peripheral neuropathy in prediabetes and diabetes. Furthermore, we demonstrate that omega-3 polyunsaturated fatty acids derived from fish oil as an effective treatment for peripheral neuropathy that occurs with chronic obesity or type 2 diabetes. Disclosure M.A. Yorek: Consultant; Self; Novo Nordisk Inc. Funding National Institute of Diabetes and Digestive and Kidney Diseases (DK107339); U.S. Department of Veterans Affairs (RX000889)
Persuading the People in Greek Participatory Communities

Field: Arts and Humanities (Social Sciences)

The need to persuade an audience was not unique to democracy, but rhetoric was most significant in participatory states with a sovereign demos. This chapter focuses on Athenian rhetoric because of the unique value of this source, and because classical Athenian democracy was the most enduring and participatory of all Greek political systems. It highlights usage of rhetoric in other Greek democracies, and focuses on the means of persuasion that Athenian speakers used in different civic situations and the historical, political, and cultural environments that influenced them, with special attention given to the way rhetoric related to the participatory aspects of membership in the community. The chapter focuses on Aristotle's division of public speaking into three genres: epideictic, forensic, and deliberative. It examines one representative oration from each genre, all dealing largely with perceptions of citizenship and military service and all informed by the ideology of a participatory community.
Recent Theoretical Results for Time Series Models with GARCH Errors

Field: Mathematics (Physical Sciences)

This paper provides a review of some recent theoretical results for time series models with GARCH errors, and is directed towards practitioners. Starting with the simple ARCH model and proceeding to the GARCH model, some results for stationary and nonstationary ARMA–GARCH are summarized. Various new ARCH–type models, including double threshold ARCH and GARCH, ARFIMA–GARCH, CHARMA and vector ARMA–GARCH, are also reviewed.
Dynamic Modes of Electromechanical Systems under Parametrical Disturbances

Field: Engineering (Physical Sciences)

The results of a theoretical and experimental investigation of the influence of damping and pitch plays on the dynamics of electromechanical systems in the zones of main, harmonic, and subharmonic resonances under parametrical disturbances are presented. Design models of electromechanical systems taking into account spring linkages, pitch plays, mechanical damping, and inconstancy of a gear ratio and reduction radius are proposed. The equations and structural schematics describing the movement of electromechanical systems under consideration in the initial values and adopted system of generalized parameters and relative units are presented. The electric drive is described by a linear mechanical characteristic taking into account the electromagnetic inertia of power circuits. The problems of linearization of electromechanical systems under parametric disturbances are considered, and the zone parameters are revealed under which it is possible. The analytical relationships for determining the optimum parameters of electric drive and the estimation of resonant amplitudes of oscillations of the elastic torque are obtained. Results of analysis of the influence of pitch-play formation on the oscillations in the zones of main and subharmonic resonances are presented. Features of these oscillations related to the magnitude of average load of transmissions and the direction of change in the frequency of parametric disturbances are considered. The reliability of theoretical regulations and conclusions of the article are confirmed by the results of industrial experience in the use of various circuits of a reduction-gear electric drive of rotation of an excavator under parametric disturbances caused by a gear wheel meshing with the gear ring.
The meaning of a gastrin response to a test meal.

Field: Medicine (Health Sciences)

Factors that may influence the magnitude of the gastrin response to a test meal have been examined in vitro by use of isolated sheets of antral mucosa obtained from 78 patients who underwent gastric resection. The amount of immunoreactive gastrin (IG) released during stimulation with the luminal pH at 7.4 increased linearly with the passage of time and stopped abruptly when the luminal pH was lowered to 2.5. The rate at which IG was released by the same stimulus at pH 7.4 was linearly related to the IG content in antral tissue (r = 0.66). The IG content in antral tissue increased during stimulation in vitro (10.05 +/- 2.09 to 19.77 +/- 3.38 pmol/mg tissue protein, P less than 0.03). These in vitro data suggest that the magnitude of the gastrin response to a test meal may be indicative of the IG content in antral tissue provided that: the tissue is in an unstimulated state when the stimulus is applied; the stimulus is applied for a standard span of time; the stimulus is applied to the antrum alone; and the inhibitory effects of acid are prevented by clamping the intraluminal pH at 7.4.
Tracheid length in Norway spruce (Picea abies (L.) Karst.) analysis of three databases regarding tree age, cambial age, tree height, inter-annual variation, radial distance to pith and log qualities.

Field: Agricultural and Biological Sciences (Life Sciences)

The study analyses three databases on tracheid length measurements in Norway spruce wood (Picea abies (L.) Karst.). The measurements cover a wide range of tree age from juvenile wood to very mature wood ( 60 cm). Fibre length was measured in three different tree heights separately for earlywood and the according latewood. The databases include the whole spectrum of log qualities that are classified in the Austrian grading rules (FHP 2006). Non-linear regression (NLR) models were applied to investigate the correlation between tracheid length and tree age, cambial age or radial distance from pith at different tree heights. Trend lines of the tracheid length regarding tree age, cambial age, tree height and interannual variation were developed achieving high correlation coefficients up to r 2 = 0.78. The applied function to describe the tracheid length trend is based on a logarithmic curve (Bailey 1920). Due to the proposed additional terms the function allows for a steeper increase of fibre length in the juvenile growth phase as well a culmination/decrease at high age. The influence of log qualities (grades) on the fibre length was illustrated. The study gives a deeper insight on tracheid cell morphology in coniferous trees and can be applied to select the most appropriate raw material for specific wood, pulp and paper products.
Web-building spiders and blood-feeding flies as prey of the notch-eared bat (Myotis emarginatus)

Field: Agricultural and Biological Sciences (Life Sciences)

(Uploaded by Plazi for the Bat Literature Project) Conservation of the endangered notch-eared bat (M. emarginatus) requires a specific action plan based on precise ecological requirements of this species. The analysis of the diet of three colonies in southern Belgium revealed: (1) spatial and seasonal variations of the diet; (2) the consumption of web-building spiders (Araneus diadematus, Araneus triguttatus, Cyclosa conica, Enoplognatha sp., Larinioides patagiatus, Neriene emphana); (3) the predominance of blood-feeding dipterans in the diet (Stomoxys calcitrans and Musca autumnalis). Since the populations of these two ectoparasitic flies are sensitive to the use of antiparasitic drugs, these drugs should be used with caution by farmers and veterinarians in the vicinity of maternity colonies.
COMPARISON OF ANTIMICROBIAL ACTIVITY AND MIC OF BRANDED AND GENERIC FORMS OF AMOXICILLIN

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The present work is about to determine the efficacy of different Branded and generic pharmaceuticals (antimicrobials).Branded formulations are at high cost, so that the poor can't afford to buy them.Therefore the generic drugs of various pharmaceutical companies are sold at low cost are checked for their therapeutic efficacy by comparing with that of branded for their efficacy (antimicrobial activity).Different branded and generic formulations of Amoxicillin were selected and their efficacy was tested by using cup plate method and minimum inhibitory concentration of drug that is effective towards microorganism.
Identification of non-linear characteristics of a class of block-oriented non-linear systems via Daubechies wavelet-based models

Field: Mathematics (Physical Sciences)

The paper deals with the identification of non-linear characteristics of a class of block-oriented dynamical systems. The systems are driven by random stationary white processes (i.i.d. random input sequences) and disturbed by a zero-mean stationary, white or coloured, random noise. The prior knowledge about non-linear characteristics is non-parametric excluding implementation of standard parametric identification methods. To recover non-linearities, a class of Daubechies wavelet-based models using only input-output measurement data is introduced and their accuracy is investigated in the global MISE error sense. It is shown that the proposed models converge with a growing collection of data to the true non-linear characteristics (or their versions), provided that the complexity of the models is appropriately fitted to the number of measurements. Suitable rules for optimum model size selection, maximizing the convergence speed, are given and the asymptotic rate of convergence of the MISE error for optimum models is established. It is shown that in some circumstances the rate is the best possible that can be achieved in non-parametric inference. We also show that the convergence conditions and the asymptotic rate of convergence are insensitive to the correlation of the noise and are the same for known and unknown input probability density function (assumed to exist). The theory is illustrated by simulation examples.
Securely Data Retrieval For Decentralized Disruption Tolerant Military Systems

Field: Computer Science (Physical Sciences)

There are some parts of the military environment, such as battlefields or hostile areas. They may suffer from intermittent network connections. They have frequent partitions. Networking DTN networking technology is a truly simple solution. DTN network, tear-resistant; it allows wireless and military personnel to carry the interaction with each other. These devices reliably protect confidential information or use external storage node commands. In these network environments, DTN is a very successful technology. If there is no wired connection between the source and the target device, the intermediate node may need information from the source node for a long time until the connection is properly established. One of the complex methods is ABE. This is a property-based encryption that meets the requirements for secure data retrieval in DTN. This concept is a password strategy Cipher text-Policy ABE (CP-ABE). It provides an appropriate way to encrypt data. Encryption includes a set of attributes that need to be decrypted to decrypt the encrypted text. Therefore, many users can be allowed to decrypt different data according to the security policy. https://journalnx.com/journal-article/20150449
Amiodarone-related thyroid dysfunction and associated outcomes in patients with heart failure - a matched case-control study

Field: Medicine (Health Sciences)

Abstract Aim The association between amiodarone-related thyroid dysfunction and the risk of worsening heart failure (HF) or death has been reported with conflicting results. Methods The study cohort was patients with HF and without a history of thyroid dysfunction (defined by medical treatment or diagnosis) who initiated treatment with amiodarone in the period 1996-2021. Within this cohort, those who developed thyroid dysfunction (cases) were identified and matched 1:3 on age, sex, calendar year, duration of HF, and time since initiation of amiodarone with patients (controls) from the same cohort and followed for the primary outcome of HF hospitalization or all-cause death at 1-year, assessed by Kaplan Meier curves and Cox regression models adjusted for ischemic heart disease, chronic kidney disease, malignancy, atrial fibrillation and ventricular tachycardia. Results The study cohort comprised 21,947 patients, of whom 4,137 (19%) developed thyroid dysfunction following initiation of amiodarone. After matching, the study population consisted of 4,063 cases (mean age 69 years, 68% men, 41.6% developed thyroid dysfunction within the first year after initiation of amiodarone) and 10,940 matched controls, (Figure 1). The index date was the date of thyroid dysfunction for cases, and for matched controls a date at a similar distance since amiodarone initiation. At 1-year follow-up, the primary outcome occurred in 1,543 (38.0%) cases and 3,681 (33.6%) matched controls (reference), adjusted hazard ratio (HR) 1.13 (95%, confidence interval CI 1.07-1.20), although this was solely driven by HF hospitalization (28.9% vs 21.8%; HR 1.32 (95% CI 1.23-1.41), whereas all-cause death was lower among cases (18.2% vs. 20.4%, HR 0.85 (95% CI 0.78-0.93), (Figure 2). Conclusions Among HF patients treated with amiodarone, the development of thyroid dysfunction was associated with an increased risk of HF hospitalization or all-cause death, but this was solely driven by the excess risk of HF hospitalization, whereas it was associated with a lower risk of all-cause death. The absence of excess mortality indicates that thyroid complications are manageable in this vulnerable population of patients with HF.Figure 1 Flowchart of the populationFigure 2 Cumulative risk
Greenhouse evaluation of growth parameters related to birdsfoot trefoil and red and white clover production on an and IC mission silt loam

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract Birdsfoot trefoil (Lotus tenius), red clover (Trifolium pratense) and white clover (Trifolium repens) were evaluated as potential forage legumes on andic soils. A greenhouse study was used to evaluate the influence of soil pH on: (1) the establishment and growth of these forage legumes, (2) N and P quantity and concentration, and (3) Rhizobium lupini and Rhizobium trifolii survival. Aluminum sulfate and finely‐ground calcium carbonate were used to adjust soil pH. Soil pH's were 4.8, 5.1, 5.6, 6.2, 6.4, 6.9, 7.0 and 7.4. Birdsfoot trefoil, red clover and white clover were grown in 15 cm pots in the greenhouse and harvested five times at approximately 20‐day intervals. Yield was measured and plant material was analyzed for total N and P. Populations of R. lupini and R. trifolii were monitored using the MPN technique. Manipulation of pH in the Mission soil was found to have a significant effect on the growth of the three forage legumes, tissue N and P concentration and uptake, and on the survival of R. lupini and R. trifolii in the soil. In general, tested parameters increased with increasing soil pH. Greatest forage yield occurred in the 6.9–7.0 pH range. The andic nature of the Mission soil requires a pH adjustment above pH 6.2 for acceptable establishment and yields of the three forage legumes studied. This is in sharp contrast to non‐andic northern Idaho soils where forage legume yields are usually not adversely affectea above pH 5.5. All three legumes appeared to have good potential ana should be evaluated under field conditions. Key words: Soil acidificationlimingN nutritionP nutrition Rhizobium lupini Rhizobium trifolii Notes Paper number 83729 of the Idaho Agricultural Experiment Station.
Research of effect of underwater backscattering on the detection of sea wave using a Slit Streak Tube Imaging Lidar

Field: Physics and Astronomy (Physical Sciences)

Slit Streak Tube Imaging Lidar (STIL) is a promising imaging system as its high frame rate and good image quality. It can output the 4-D image (3-D range image + 1-D intensity image). And its functionality demonstrated for imaging of short scale ocean surface waves. Accuracy of sea-wave height measurement requires high resolution range supplied by this system. But the backscattered of sea water has an effect on the extraction of range and intensity information. In this paper, according to STIL, we deduce the signals of energy of reflected and backscattered light and analysis the effect on the extraction of range and intensity information.
FLT3-ITD and TLR9 use Bruton tyrosine kinase to activate distinct transcriptional programs mediating AML cell survival and proliferation

Field: Medicine (Health Sciences)

Key Points Two novel transducer modules consisting of BTK in combination with either FLT3-ITD or TLR9 induce distinct oncogenic signaling programs. This study suggests subtype-specific treatment strategies, including BTK/FLT3 inhibitor combinations, and shows how TLR9 affects AML biology.
Issue Publication Information

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleIssue Publication InformationCite this: ACS Sustainable Chem. Eng. 2023, 11, 18, XXX-XXXPublication Date (Web):May 8, 2023Publication History Published online8 May 2023Published inissue 8 May 2023https://doi.org/10.1021/scv011i018_1681743Copyright © 2023 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views12Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (171 KB) Get e-Alertsclose Get e-Alerts
Isomerism in coordinatively unsaturated tricarbonyl-.eta.2-etheneiron complexes

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsomerism in coordinatively unsaturated tricarbonyl-.eta.2-etheneiron complexesTerence M. Barnhart, Richard F. Fenske, and Robert J. McMahonCite this: Inorg. Chem. 1992, 31, 13, 2679–2681Publication Date (Print):June 1, 1992Publication History Published online1 May 2002Published inissue 1 June 1992https://pubs.acs.org/doi/10.1021/ic00039a005https://doi.org/10.1021/ic00039a005research-articleACS PublicationsRequest reuse permissionsArticle Views42Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Save our soles SG : SOS SG

Field: Health Professions (Health Sciences)

Save Our Soles SG (SOS SG) was a campaign aimed at empowering women with the knowledge and awareness of the short term and long term health consequences of wearing high heels, and what they could do to care for their feet. Four final-year students of the Wee Kim Wee School of Communication and Information at the Nanyang Technological University conceptualised, planned, and ran this campaign, with the hopes of motivating more women to save their soles. SOS SG was targeted at working women aged 21 to 45 years old. Wearing high heels is a common preference, or even workplace requirement for some. The impact that wearing high heels has on women’s health had been well-documented, but this culture seemed to persist both globally and locally. This had led to outcry in some parts of the world where they had taken their companies to court to dispute painful workplace rules that forced women to wear high heels. While we recognised the world would take time to catch up and adjust to caring for women, we could at least empower women to care for themselves first. This report looked into the thoughts, perceptions, and habits of women in Singapore on the issue of wearing high heels. It also covered the planning, execution, and evaluation of the campaign to spread awareness of the health issues and good habits that could be adopted. Finally, the limitations and solutions were also discussed. An appendix with all supporting materials can be found at the end of the report.