jimnoneill/paper-to-field-training huggingface dataset:
Prevalence of Depression and Anxiety Symptoms Among Parents of Hospitalized Children in 14 Countries

Field: Medicine (Health Sciences)

Background/Objectives: Despite the importance of parent mental health for child health, there are no global prevalence data on parental mental health symptoms when children are hospitalized. We aimed to describe depression and anxiety symptom prevalence and associated factors among parents of hospitalized children. Methods: We conducted this 14-country prospective cohort survey with parents/primary caregivers staying at a nearby Ronald McDonald House® during their child’s hospital treatment. We used the Hospital Anxiety and Depression Scale to measure depression and anxiety symptoms and validated scales and theory-based questions to measure parent, family, and child covariates. We calculated the prevalence of clinically significant or concerning symptoms of depression and anxiety, and used multivariable regression analyses to examine associations between covariates and outcomes. Results: Among 3350 participants, 1789 (49.7%) reported depression symptoms and 2286 (69.0%) reported anxiety symptoms. Worry about housing and poorer ratings of their child’s health were associated with increased risk of depression symptoms. Poorer rating of the child’s health, living with a partner, and discrimination in daily life were associated with increased risk of anxiety symptoms. Higher levels of self-care, hospital family-centered care, and social support were associated with reduced risk of depression symptoms. Higher levels of self-care and social support were associated with reduced risk of anxiety symptoms. Conclusions: Clinically significant or concerning depression and anxiety symptoms are common among parents of hospitalized children globally. Hospitals should consider offering routine mental health symptom screening and preventative mental health and support services to all parents.
The Correlation Between Immunohistochemistry Findings and Metastasis in Squamous Cell Carcinoma: A Review

Field: Medicine (Health Sciences)

BACKGROUND Cutaneous squamous cell carcinoma (SCC) is the second most common type of skin cancer. Only 2% to 5% of SCCs metastasize; however, those do carry a poor prognosis. Immunohistochemistry (IHC) is widely used by pathologists to characterize skin cancers and provide clinically useful information. OBJECTIVE To evaluate the potential prognostic associations between IHC findings and metastasis in SCC. METHODS Searches were conducted in MEDLINE via PubMed for articles published between 1999 and 2019. Search criteria included key words “immunohistochemistry” and “cutaneous squamous cell carcinoma.” Six hundred and fifty-three articles were returned and screened, which ultimately left 31 for inclusion in our manuscript. RESULTS Thirty-one articles analyzed in this review included a discussion of the expression of a particular IHC marker and the associated risk of metastasis and/or clinical utility of IHC markers in SCC, especially metastatic SCC. Markers that had several or more studies supporting clinical utility were E-cadherin, podoplanin, CD8 + T cells, PD-L1, epidermal growth factor receptor, and Cyclin D1. CONCLUSION Immunohistochemistry profiling of SCC may be useful in select cases when providing a prognosis remains challenging and in identification of potential therapeutic targets for high-risk or metastatic tumors.
Linezolid in the treatment of MDR-TB: a retrospective clinical study

Field: Medicine (Health Sciences)

There is limited information on Chinese patients with multidrug-resistant tuberculosis (MDR-TB) treated with a linezolid-containing regimen.To examine treatment outcomes among MDR-TB patients who were treated with linezolid at the Shanghai Pulmonary Hospital, China.We retrospectively reviewed 151 patients who were treated for MDR-TB from 2007 to 2010.Eighteen MDR-TB patients, including 15 with extensively drug-resistant TB, received linezolid as part of their individualised treatment regimens. Patients had isolates resistant to a median of 7 drugs (range 5-11). Of the 18 cases, 17 had cavitary changes and positive sputum smear microscopy results at the time of MDR-TB diagnosis. Culture conversion occurred in all cases at a median of 7 weeks. At data censure, 9 of the 18 patients had achieved treatment success. Three continued to receive treatment. There were no deaths. Six patients had a poor outcome, including 1 default, 2 treatment failures and 3 relapses. Side effects occurred in 17 patients, including myelosuppression, neurotoxicity and gastrointestinal adverse events. Adverse events were managed by combinations of temporary suspension of linezolid in 1 patient, dose adjustment in 17 patients and symptom management in 13 patients.Linezolid may have efficacy in the treatment of MDR-TB, although treatment was complicated by adverse events.
Diindeno[1,2,3,4-defg;1′,2′,3′,4′-mnop]chrysenes: solution-phase synthesis and the bowl-to-bowl inversion barrier

Field: Chemistry (Physical Sciences)

Diindeno[1,2,3,4-defg;1',2',3',4'-mnop]chrysenes 2 were straightforwardly prepared in around 20% yield from 9,10-diarylphenanthrenes 3 by palladium-catalyzed intramolecular arylations. The bowl-to-bowl inversion barrier for buckybowl 2-iPr is predicted to be approximately 7 kcal mol(-1) based on density functional theory calculations and this value is consistent with the results of a variable-temperature (1)H-NMR study.
Personal web content management system : an honors thesis [(HONRS 499)]

Field: Computer Science (Physical Sciences)

There is a definite need for server-side content management software on the World Wide Web—both for businesses and for individuals. Of the various server-side programming languages that are available (at least four of which I have some experience with), PHP seemed to make the most sense for my application, primarily because it is free. For the same reason, I chose a MySQL database for the back end.The system I have developed allows multiple users to post news/weblog entries, add pages dynamically, and publish articles in an organized directory structure all without writing code.
Environmental Feature Causing a Bloom of the Novel Dinoflagellate Heterocapsa circularisquama (Dinophyceae) in Uranouchi Bay, Kochi Prefecture, Japan

Field: Environmental Science (Physical Sciences)

To study the environmental features causing a bloom of the novel dinoflagellate Heterocapsa circularisquama (Dinophyceae), hydrographic and chemical aspects were measured in the Uranouchi Bay, Kochi Prefecture, Japan, from January to December, 1997. The cell density of H. circularisquama increased rapidly in early October, and dropped sharply in mid-October. Growth rate of H, circularisquama during bloom period appeared 1.50 division day under high water temperature (25) and salinity (32 psu) conditions. Althought the result from hydrographic aspect indicated good condition for their growth, dissolved inorganic phosphorus (DIP) concentration in surface layer before bloom formation was less than 0.70uM, which is lower than their half saturation constant(Ks). Dissolved inorganic nitrogen(DIN): DIP ratio was > 30, indicating potential P-limitation. However, before bloom formation period of H. circularisquama, DIP concentrations were high in bottom layer (> 4.0 uM). Some studies reported that H. circularisquama had the ability to migrate vertically and to utilize dissolved organic phosphorus (DOP). Thus, DIP in bottom layer might have been utilized by H. circularisquama for their growth.DOP might have weakly affected their growth because of low reactive DOP concentrations owing to low DOP concentration (ca. 0.39 uM). Thus, if nutrient condition of bottom layer in Uranuchi Bay is not improved, the outbreaks of H. circularisquama red tides may became an annual feature.
THE INFLUENCE OF LIQUIDITY, ACTIVITY, AND SOLVENCY ON STOCK PRICES WITH PROFITABILITY AND CORPORATE SOCIAL RESPONSIBILITY DISCLOUSURE AS INTERVING VARIABLES IN THE RESTAURANT, HOTEL AND TOURISM SUB-SECTOR

Field: Economics, Econometrics and Finance (Social Sciences)

The purpose of this study was to determine the effect of liquidity, activity, and solvency on stock prices by using two intervening variables, namely profitability and CSRD. This research uses the causal explanatory method which is a type of research where the researcher explains the causal relationship between the variables through hypothesis testing, namely testing hypotheses based on the theory that has been formulated previously, and then the data that has been obtained is calculated through a quantitative approach. Liquidity has no significant effect on Profitability, Liquidity has no significant effect on CSRD, Liquidity has no significant effect on Stock Price, Activity has no significant effect on Profitability, Activity has no significant effect on CSRD, Activity has no significant effect on Stock Price, Solvency has no significant effect on Profitability, Solvency has no significant effect on CSRD, Solvency has no significant effect on stock prices, profitability has no significant effect on stock prices, CSRD has no significant effect on stock prices.
In recurrent C difficile infection, oral FMT capsules have a pooled cure rate of 82% (low-quality evidence)

Field: Medicine (Health Sciences)

Du C, Luo Y, Walsh S, Grinspan A. Oral fecal microbiota transplant capsules are safe and effective for recurrent Clostridioides difficile infection: a systematic review and meta-analysis. J Clin Gastroenterol. 2021;55:300-8. 33471490.
Rise in antihistamine-related deaths prompts call for move to POM status

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Researchers have recommended reclassifying first-generation sedating antihistamines as a prescription-only medicine (POM), citing an increase in the number of deaths involving these drugs. A team of researchers at King’s College London studied drug-related deaths reported to the National Programme on Substance Abuse Deaths (NPSAD) in England between 1999 and 2019. They identified 1,666 antihistamine detections […]
cc w/attach

Field: Energy (Physical Sciences)

progress reports and describes the status of activities undertaken, and results achieved to meet the U. S. Department ofEnergy&apos;s (DOE) commitments as described in Reference 1. DOE has made good progress this quarter toward closing safety issues related to Pulse Jet Mixing at the Waste Treatment and Immobilization Plant. In accordance with the IP, no deliverables were completed or due during this reporting period. Details may be found in thc attached report. If you have any questions, please contact me at (509) 376-6727 or your staff may contact Ben Harp,
Association Between Nonalcoholic Fatty Liver Disease and the Incidence of Asthma in Adults: Finding from a Nationwide Study in Korea

Field: Medicine (Health Sciences)

Abstract Asthma and nonalcoholic fatty liver disease (NAFLD) are chronic diseases and are known to be associated with metabolic abnormalities. We aimed to clarify the association between NAFLD and the incidence of asthma in a large population-based cohort. We selected 160,603 healthy individuals without comorbidities from the National Health Insurance Service-National Sample cohort during 2009–2014. . NAFLD was defined by a surrogate marker, the fatty liver index (FLI). During a median of 5.08 years’ follow-up, 16,377 subjects (10.2%) were newly diagnosed with asthma and categorized into three groups according to FLI. The cumulative incidence of asthma was higher in subjects with higher vs. lower FLIs (FLI < 30 10.1%, 30 ≤ FLI < 60 10.8%, FLI ≥ 60 10.5% ). Higher FLI associated with an increased incidence of asthma (Harzard ratios (HR)highest vs. lowest FLI, 1.25; 95% CI, 1.15-1.36). The results using another definition of NAFLD as measured by hepatic steatosis index (HIS) are similar to the primary results. This association was more pronounced in women than in men (HR 1.46; 95% CI, 1.13-1.64 vs. HR 1.07; 95% CI, 0.94-1.20). This study demonstrated that NAFLD as measured by FLI and HIS may influence the incidence rates of asthma in adults, especially in women.
SH481470.07FU

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
High-frequency microstrip cross resonators for circular polarization electron paramagnetic resonance spectroscopy

Field: Physics and Astronomy (Physical Sciences)

In this article we discuss the design and implementation of a novel microstrip resonator which allows absolute control of the microwaves polarization degree for frequencies up to 30 GHz. The sensor is composed of two half-wavelength microstrip line resonators, designed to match the 50 Ω impedance of the lines on a high dielectric constant GaAs substrate. The line resonators cross each other perpendicularly through their centers, forming a cross. Microstrip feed lines are coupled through small gaps to three arms of the cross to connect the resonator to the excitation ports. The control of the relative magnitude and phase between the two microwave stimuli at the input ports of each line allows for tuning the degree and type of polarization of the microwave excitation at the center of the cross resonator. The third (output) port is used to measure the transmitted signal, which is crucial to work at low temperatures, where reflections along lengthy coaxial lines mask the signal reflected by the resonator. Electron paramagnetic resonance spectra recorded at low temperature in an S=5/2 molecular magnet system show that 82% fidelity circular polarization of the microwaves is achieved over the central area of the resonator.
Prevalence of and factors associated with multimorbidity among 18 101 adults in the South East Asia Community Observatory Health and Demographic Surveillance System in Malaysia: a population-based, cross-sectional study of the MUTUAL consortium

Field: Medicine (Health Sciences)

Objectives To assess the prevalence and factors associated with multimorbidity in a community-dwelling general adult population on a large Health and Demographic Surveillance System (HDSS) scale. Design Population-based cross-sectional study. Setting South East Asia Community Observatory HDSS site in Malaysia. Participants Of 45 246 participants recruited from 13 431 households, 18 101 eligible adults aged 18–97 years (mean age 47 years, 55.6% female) were included. Main outcome measures The main outcome was prevalence of multimorbidity. Multimorbidity was defined as the coexistence of two or more chronic conditions per individual. A total of 13 chronic diseases were selected and were further classified into 11 medical conditions to account for multimorbidity. The conditions were heart disease, stroke, diabetes mellitus, hypertension, chronic kidney disease, musculoskeletal disorder, obesity, asthma, vision problem, hearing problem and physical mobility problem. Risk factors for multimorbidity were also analysed. Results Of the study cohort, 28.5% people lived with multimorbidity. The individual prevalence of the chronic conditions ranged from 1.0% to 24.7%, with musculoskeletal disorder (24.7%), obesity (20.7%) and hypertension (18.4%) as the most prevalent chronic conditions. The number of chronic conditions increased linearly with age (p<0.001). In the logistic regression model, multimorbidity is associated with female sex (adjusted OR 1.28, 95% CI 1.17 to 1.40, p<0.001), education levels (primary education compared with no education: adjusted OR 0.63, 95% CI 0.53 to 0.74; secondary education: adjusted OR 0.60, 95% CI 0.51 to 0.70; tertiary education: adjusted OR 0.65, 95% CI 0.54 to 0.80; p<0.001) and employment status (working adults compared with retirees: adjusted OR 0.70, 95% CI 0.60 to 0.82, p<0.001), in addition to age (adjusted OR 1.05, 95% CI 1.05 to 1.05, p<0.001). Conclusions The current single-disease services in primary and secondary care should be accompanied by strategies to address complexities associated with multimorbidity, taking into account the factors associated with multimorbidity identified. Future research is needed to identify the most commonly occurring clusters of chronic diseases and their risk factors to develop more efficient and effective multimorbidity prevention and treatment strategies.
Radiation in the treatment of meningeal leukemia.

Field: Medicine (Health Sciences)

At the present time, a successful regimen for the eradication of occult meningeal leukemia, following induction of a first complete remission in acute lymphoid and undifferentiated childhood leukemia, is the combination of cranial radiotherapy in a dose of 1800 rads in 10 fractions in 12--14 days with six doses of intrathecal methotrexate. This regimen, when given with prednisone and vincristine with or without L-asparaginase for induction and daily oral 6-mercaptopurine and weekly methotrexate for maintenance, can be expected to give a relapse rate for isolated meningeal leukemia of approximately 5% during the first 2 years of follow-up. A modification of this regimen utilizing craniospinal radiation with prior and concurrent intrathecal methotrexate is given for the treatment of overt meningeal leukemia at diagnosis or for an isolated first relapse with meningeal leukemia. Radiation technique and morbidity are discussed.
ANTISTREPTOLYSIN AND STREPTOCOCCAL ANTIHYALURONIDASE TITERS IN SERA OF HORMONE-TREATED AND CONTROL PATIENTS WITH ACUTE RHEUMATIC FEVER

Field: Medicine (Health Sciences)

Streptococcal antihyaluronidase and antistreptolysin O titers were determined at the time of hospitalization and 1 month later for patients with acute rheumatic fever included in a clinical study of the effects of ACTH and cortisone on this disease. The sera of the groups of patients receiving cortisone and ACTH showed a greater fall in serum titer in this interval in both tests than did the symptomatically treated control patients.
The role of HVDC voltage waveforms on partial discharge activity in paper/oil insulation

Field: Engineering (Physical Sciences)

This paper discusses the role of high voltage direct current (HVDC) voltage waveforms on partial discharge (PD) activity in paper/oil insulation systems. A variety of voltages were simulated by the PSIM software and synthesized using a high voltage amplifier. Kraft paper sheets were used to create defects incepting PD. The PD signals were coupled by a high frequency ferrite core current transformer. PD quantities including PD inception voltage (PDIV), pattern, amplitude distribution and repetition rate were recorded. The results show that the PDIV under notched voltage becomes higher increasing firing and overlap angles. PD patterns change with the HVDC voltage waveforms showing that large PD likely occurs at the rising front of the notches. PD amplitude and repetition rate are both directly proportional to notch depth. It is expected that such results can improve the design of UHV converter transformers.
Prokaryotic Community Structures in a Thermophilic Anaerobic Digestion Reactor Converting Poly( l -Lactic Acid) for a Long Period Revealed by 16S rRNA Gene Amplicon Sequencing

Field: Immunology and Microbiology (Life Sciences)

Little information on poly( l -lactic acid) (PLLA) treatment-associated microbiota in thermophilic anaerobic digestion reactors is available. Here, we provide 16S rRNA gene sequence data on microbiota in a thermophilic anaerobic digestion reactor converting PLLA to methane for 336 days. Data comprising 99,566 total high-quality reads were tabulated at the taxonomic class level.
Management of Self-Care Among Patients With Type 2 Diabetes and its Relationship to their Quality of Life

Field: Health Professions (Health Sciences)

Background: In these exceptional circumstances the country is going through; Self-care management for patients with Type 2 diabetes mellitus (DM2) may be affected by many factors that may affect their quality of life, this contributes to the deterioration of their health and psychological conditions and has negative effects on various aspects of their lives.Aims of the study: This study aims to determine the relationship between self-care management and quality of life among patients with DM2.Methodology: In this study, a descriptive method research design was used. The study was started on 22/10/2022 through 14/12/2022. A nonprobability (possible) sample was selected of 50 patients with T2DM; those who followed their health condition in the Teshreen teaching hospital during the mentioned period. Data were collected using some previously prepared two questionnaires. Descriptive statistics (frequencies, percentages, mean and standard deviation) and inferential statistics (contingency coefficient) were used in data analysis.Results: The study showed that the highest percentage of participants had a good level of self-care measure, and that the highest percentage of them had a moderate level of quality of life, and there was no significant statistically significant relationship between self-care measure and patient quality of life.Conclusion: The study showed that there is no statistically significant relationship between the level of self-care management and patient quality of life.Recommendation: Improving self-care measures in patients with type 2 diabetes requires a multifaceted effort, and it is important to follow the recommendations to promote general health and improving the quality of life in these patients, such as exercising regularly and eating a healthy balanced diet.
Experimental Compromise and Mechanistic Approaches to the Evolutionary Ecology of Interacting Daphnia Species

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract The experimental approach has been tremendously useful in community ecology, but it has led to a codified design for experiments, which has been characterized as phenomenological by some critics (Dunham, this volume; Petraitis, this volume). In the conventional approach, investigators select a particular system (i.e., an assemblage at a particular place and time) and conduct perturbation experiments to determine if certain general processes occur (e.g., species removals to detect the occurrence of predation or competition). In some cases, multiple factors are manipulated to determine the “relative importance” of these factors on aspects of the community. This tradition of experiments has rapidly escalated, and standard means have been developed and improved to deal with a wide array of methodological, statistical, and inferential issues (Hurlburt 1984, Hairston 1989, Manly 1992, Underwood 1995). Whereas early experiments often suffered from an array of such problems (Table 5-1), more recent work reflects a greater awareness of these important issues. Improvements on the experimental approach, however, continue to deal poorly with what are perhaps the most important concerns: generality and extrapolation. Advances in these areas come at great cost.