jimnoneill/paper-to-field-training huggingface dataset:
Preemptive Analgesic Efficacy of Parecoxib for Reducing Postoperative Pain in Patients Undergoing Gynecological Surgery

Field: Medicine (Health Sciences)

Objective: This study aimed to evaluate the effectiveness of preemptive parecoxib in reducing postoperative pain following gynecological surgery. Materials and Methods: A double-blind, randomized study involved 168 patients undergoing laparotomy gynecological procedures, including total hysterectomy, adnexal surgery, and surgical staging, between November2023 and July 2024. Patients were randomly assigned to receive either intravenous parecoxib (n = 82) or normal saline (n = 86) 15 minutes before surgery. Postoperative pain was measured using a visual analog scale at 2, 6, 12, and 24 hours. Morphine consumption within the first 24 hours post-surgery was recorded, along with any adverse events related to parecoxib and the length of hospital stay. Results: Mean pain scores at 2, 6, 12, and 24 hours postoperatively were lower in the treatment group compared to the control group (5.3 vs. 5.7, p = 0.261; 3.7 vs. 5.0, p < 0.001; 3.3 vs. 5.1, p < 0.001; 3.5 vs. 4.0, p = 0.164, respectively). The mean 24-hour postoperative morphine consumption was significantly lower in the treatment group (4 ± 8 mg vs. 8 ± 5 mg, p < 0.001). No significant adverse events occurred between the groups. The total length of hospital stay was similar between the two groups (3.4 ± 1.8 vs. 3.5 ± 1.4 days, p = 0.698). Conclusion: Preemptive parecoxib significantly reduced pain at 6 and 12 hours post-surgery and reduced morphine use within 24 hours, with no significant effect on hospital stay duration in gynecological surgery.
Sex Differences In Carotid Baroreflex Control Of Heart Rate At Rest And During Dynamic Exercise In Humans

Field: Medicine (Health Sciences)

Previous studies in animals have demonstrated that the arterial baroreflex control of heart rate (HR) was greater in female compared to male rodents. In contrast, equivocal results have been reported in humans with several studies reporting that young women, in fact, exhibit a reduced cardiac baroreflex sensitivity compared to young men. In addition, to date, no studies have examined differences in the baroreflex control of HR during exercise in young men and women. PURPOSE: To determine if the carotid baroreflex control of HR differs between young men and women at rest or during dynamic exercise. METHODS: Beat-to-beat HR and blood pressure were measured in nine young women (22±1 yr) and men (22±1 yr) at rest and during steady-state leg cycling at 50% HR reserve. All women were studied during the early follicular phase of the menstrual cycle (days 2-5). Five second pulses of neck suction (NS, -60 Torr) and neck pressure (NP, + 40 Torr) were applied to selectively load and unload the carotid baroreceptors, respectively. In addition, HR variability analyses were employed to investigate time and frequency domain indices of parasympathetic and sympathetic control of HR. RESULTS: At rest and during exercise, HR responses to NS were significantly greater in women than men (rest, D -16±3 women vs. D -8±1 men bpm, P = 0.002; exercise, D -17±3 women vs. D -6±1 men bpm, P = 0.004), whereas responses to NP were similar between groups (rest, D + 7±1 women vs. D + 5±1 men bpm, P = 0.222; exercise, D + 4±1 women vs. D + 2±1 men bpm, P = 0.096). In addition, there were no differences in HR variability measurements between women and men both at rest and during exercise. CONCLUSION: Carotid baroreflex mediated HR responses to a hypertensive challenge are greater in young women both at rest and during exercise. In contrast, the ability of the carotid-cardiac baroreflex to respond to a hypotensive challenge is similar between young women and men. Overall, these preliminary data suggest that sex differences in cardiac baroreflex responses are selective to hypertensive challenges both at rest and during exercise.
Hemobilia from a ruptured hepatic artery aneurysm in a 16-year-old girl.

Field: Medicine (Health Sciences)

A 16-year-old girl with hepatic artery aneurysm due to fibromuscular dysplasia which caused hemobilia is presented. This most unusual and life-threatening type of gastrointestinal bleeding was successfully treated by ligation of the common hepatic and gastroduodenal arteries. The clinical aspects and operative procedures of hepatic artery aneurysm are discussed.
P06.03: Reference ranges for papillary muscle areas of the fetal heart atrioventricular valves by three‐dimensional ultrasonography

Field: Medicine (Health Sciences)

To establish reference ranges for the papillary muscles areas of the fetal heart mitral and tricuspid valves between 18w0d and 34w6d of gestation by three-dimensional ultrasound (3DUS) using spatio-temporal image correlation (STIC) in the rendering mode. We realized a retrospective and prospective study with analysis of 310 normal fetal heart 3D STIC volume datasets collected between 2010 and 2013 in the Department of Obstetrics, Paulista School of Medicine/Federal University of São Paulo (EPM-UNIFESP). In order to obtain the papillary muscles areas by rendering mode, the four chamber view was scanned as reference plane. The papillary muscles atrioventricular valves were the antero-lateral (MPAL) and postero-medial (MPPM) to the mitral and the antero-superior (MPA), inferior (MPI) and septal (MPS) to the tricuspid valve. Polynomial regressions were realized with the adjustments by the determination coefficient (R2). The mean areas of the papillary muscles of mitral valve (MPAL and MPPM) ranged from 0.05 to 0.05 cm2 in the 20w0d and 0.18 to 0.17 cm2 in the 34w6d of gestation, respectively. The mean areas of the papillary muscles of tricuspid valve (MPA, MPI and MPS) ranged from 0.05, 0.04 and 0.04 cm2 in the 20w0d to 0.18, 0.16 and 0.18 cm2 in the 34w6d of gestation, respectively. The identification of the papillary muscles was possible in the most of 3D STIC volume datasets, enabling to the determination of the reference ranges of fetal heart atrioventricular valve areas in the rendering mode.
The Topoisomerase I Inhibitor Irinotecan and the Tyrosyl‐DNA Phosphodiesterase 1 Inhibitor Furamidine Synergistically Suppress Murine Lupus Nephritis

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective The treatment of lupus nephritis is still an unmet medical need requiring new therapeutic approaches. Our group found recently that irinotecan, an inhibitor of topoisomerase I (topo I), reversed proteinuria and prolonged survival in mice with advanced lupus nephritis. While irinotecan is known to stabilize the complex of topo I and DNA, the enzyme tyrosyl‐DNA phosphodiesterase 1 (TDP‐1) functions in an opposing manner by releasing topo I from DNA. Therefore, we undertook this study to test whether the TDP‐1 inhibitor furamidine has an additional effect on lupus nephritis when used in combination with irinotecan. Methods NZB/NZW mice were treated with low‐dose irinotecan and furamidine either alone or in combination beginning at age 26 weeks. DNA relaxation was visualized using gel electrophoresis. Binding of anti–double‐stranded DNA (anti‐dsDNA) antibodies to DNA modified by topo I, TDP‐1, and the topo I inhibitor camptothecin was determined by enzyme‐linked immunosorbent assay. Results Compared to treatment with either agent alone, simultaneous treatment with low‐dose irinotecan and furamidine significantly improved survival of NZB/NZW mice. Similar to what has been previously shown for irinotecan alone, the combination treatment did not change the levels of anti‐dsDNA antibodies. In vitro, recombinant TDP‐1 increased topo I–mediated DNA relaxation, resulting in enhanced binding of anti‐dsDNA antibodies. In combination with topo I and camptothecin, TDP‐1 reversed the inhibitory effects of camptothecin on DNA relaxation and anti‐dsDNA binding. Conclusion Affecting DNA relaxation by the enzymes topo I and TDP‐1 and their inhibitors may be a promising approach for the development of new targeted therapies for systemic lupus erythematosus.
Experiences of Teachers and Pupils on E-learning Prepardness in Selected Urban Schools of Lusaka District, Zambia: An Interpretive Phenomenological Study

Field: Social Sciences (Social Sciences)

The study focused on the experiences of teachers and pupils on e-learning preparedness in selected urban schools of Lusaka anchored on interpretive phenomenological perspective. The aim of the study was to explore the experiences of teachers and pupils on e-learning and establish the measures put in place on e-learning preparedness in the selected schools of Lusaka urban. The study used an interpretive phenomenological theoretical framework based on discussions and reflections on direct sensory observations and experiences of the learners. The starting point for using interpretive phenomenology in this research was our ability to approach this research without knowing a priori assumptions. Phenomenological theoretical framing has been used as a broad and loose name for various analyses that have emphasized experiences, interpretations, narratives, and discourse based on the phenomenological orientation of social science philosophy. Methodologically, employed a qualitative approach particularly in analyzing data. To do so, the study took a total sample size of 25 participants such as 10 pupils, 9 ICT teachers, 2 Head Teachers, 2 specialists from the Curriculum Development Centre (CDC) equaling to the total of 25 participants. Technically, the researchers used purposive sampling, specifically homogenous sampling to select head teachers, pupils, and curriculum experts. Data was collected using detailed Interview Guide, focus group discussion and observation Checklist on the preparedness of e-learning in selected schools of Lusaka, district in Zambia. Further, data was analysed using thematic analysis where major themes were drawn and coded. Based on the study findings it is evident to note the teacher’s experiences and challenges of e-learning preparedness were due to the lack of ICT infrastructure, lack of trained ICT teachers, Poor network connectivity, lack of acceptance to new technology, electricity load shedding and the lack of parental involvement in e-learning programmes. Further, on usage, the study revealed that pupils did not know how to use the e-learning platforms, and mostly there is inadequate skills and knowledge of eLearning software to both teachers and learners. The study postulates the strategies on e-learning preparedness that should include training of Trainers of ICT, Building ICT infrastructure, and ensuring that ICT is a compulsory subject from primary to secondary schools. Additionally, a continuous Professional Development for all teachers on e-learning, monitoring and evaluating of e-learning assessments and feedback should be encouraged in all schools. The study recommended the forgoing to authorities in the education sector for sustainability, as case studies and best practices, digital literacy and pedagogical approach applicable in Zambia.
A New Method for Predicting Erosion Damage of Suddenly Contracted Pipe Impacted by Particle Cluster via CFD-DEM

Field: Engineering (Physical Sciences)

A numerical study on the erosion of particle clusters in an abrupt pipe was conducted by means of the combined computational fluid dynamics (CFD) and discrete element methods (DEM). Furthermore, a particle-wall extrusion model and a criterion for judging particle collision interference were developed to classify and calculate the erosion rate caused by different interparticle collision mechanisms in a cluster. Meanwhile, a full-scale pipe flow experiment was conducted to confirm the effect of a particle cluster on the erosion rate and to verify the calculated results. The reducing wall was made of super 13Cr stainless steel materials and the round ceramsite as an impact particle was 0.65 mm in diameter and 1850 kg/m3 in density. The results included an erosion depth, particle-wall contact parameters, and a velocity decay rate of colliding particles along the radial direction at the target surface. Subsequently, the effect of interparticle collision mechanisms on particle cluster erosion was discussed. The calculated results demonstrate that collision interference between particles during one cluster impact was more likely to appear on the surface with large particle impact angles. This collision process between the rebounded particles and the following particles not only consumed the kinetic energy but also changed the impact angle of the following particles.
FRANSUZ TILI FONETIKASINI QIYOSLAB O'RGANISHNING AHAMIYATI GAPIRISH KO'NIKMASINI RIVOJLANTIRISHDA DIALOGNING ROLI

Field: Arts and Humanities (Social Sciences)

Mazkur maqolada fransuz tili fonetikasining o’rganishda qiyosiy tahlilning ahamiyati hamda, fransuz tili fonetikasini o’qitishda axborot texnologiyalardan foydalanishning samarasi xususida so’z yuritilgan. Shu bilan birgalikda utaxassisligi fransuz tili bo‘lgan talabalarning og‘zaki nutqini rivojlantirishda dialoglar orqali ularning muloqot kompetensiyasini o‘stirishning ahamiyati haqida ma’lumotlar berilgan.
CSD 2078529: Experimental Crystal Structure Determination

Field: Chemistry (Physical Sciences)

An entry from the Inorganic Crystal Structure Database, the world’s repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the joint CCDC and FIZ Karlsruhe Access Structures service and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Comparison of Oral Health Status and Treatment Needs in Autistic and Non-Autistic Children

Field: Health Professions (Health Sciences)

Background: Dental treatment need is identified as the greatest neglected health need of children with developmental disabilities. The most commonly known developmental disorder is autism, and there is a recent increase in the diagnosis of autism cases. The aim of this study is to bring to light that providing quality dental care and inculcating dental education programmes can significantly improve the oral conditions of institutionalized autistic children, thereby improving their lifestyle. Materials and Methods: The study conducted an institutionally based case-control study on 50 children with autism, selected from two special schools in Chennai, India. The total number of decayed, missing, and filled teeth was assessed for the institutionalized autistic group undergoing dental education programme and the non-autistic group selected from our general hospital. Oral Hygiene Index-Simplified (OHI-S) and the DMF score were also calculated for both groups. Results: There was a statistically significant difference in OHI scores between institution trained autistic children and non-autistic controls, but we found no significant difference in decayed, missing, and filled teeth. Conclusion: Autistic children exhibit good cooperation and good response to Dental education programmes, significantly improving their oral health conditions.
Task Classification: Towards Tasks Correlation for Combinatorial Auction Mechanism in Crowdsourcing

Field: Computer Science (Physical Sciences)

People experience a revolution of society when the crowdsourcing period comes. The social reform changed the way of work and lifestyle. And the popularity of crowdsourcing has brought a new opportunity for mobile computing and online auctions. Because of the significance of incentivizing worker participation in crowdsourcing system, the correlative theories of auction-based incentive mechanisms have been proposed in past literature. Combinatorial auctions can be used to reach efficient resource and task allocations in Multi-agent systems where the items are complementary or substitutable. Although many good auction-based incentive mechanisms can attract more participation, facing a large-scale of complex social perception tasks in the market, a combinatorial auction mechanism which simply relies on to allocate resources is not efficiently. In order to solve this problem, we design two algorithm models to classify all crowdsourcing-tasks into many groups according to the intentions that the workers provided, and then the workers and the crowdsourcing platform start the combinatorial auction for each task-group. The first model, namely the frequent-driven model, adopts correlation analysis technology, and the second model, namely weight-driven model, use a method that combines the concept of weight and the hierarchical clustering technology to solve problems.
THE SPEECH ACTS OF COMPLIMENTS AMONG JAPANESE TEENAGERS IN JAPANESE ANIME FILMS

Field: Arts and Humanities (Social Sciences)

This study aimed to identify the forms of expressive speech acts of compliments and to describe the forms of perlocutionary acts that appear in the anime Yahari Ore no Seishun Love Come wa Machigatteiru and ReLife. This research used Searle’s speech act theory, Holmes' complimenting speech act, and Alston’s verbs of perlocutionary. The study applied descriptive method. The data were collected from observation and notes based on the techniques for analyzing direct elements. The data were presented in an organized set of information, allowing for conclusions and action analysis. Based on the results of the research, it was found that expressive speech acts in the forms of compliments were dominantly influenced by the speaker's ability. Meanwhile, the dominant perlocutionary verbs in the compliments refer to encouraging, irritating, and attracting attention.
Polymer Chain Alignment in Shape Memory Polymer

Field: Materials Science (Physical Sciences)

Since their development, shape memory polymers, urethanes, styrenes, and the like, have been of increasing interest in advanced material and structure design. The following is an experimental investigation into the effect polymer chain alignment has on the mechanical properties of a particular styrene shape memory polymer, Veriflex®. Aligning the polymer chains results in several material anisotropies; giving rise to the possibility of controllable, directional shape memory and modulus behavior and a basis for a multitude of prospective design concepts.
[Endoluminal angioplasty, in situ thrombolysis and arterial endoprosthesis. Immediate and long-term results (2 to 8 years): report of 5,216 operations].

Field: Medicine (Health Sciences)

Over a period of 8 years, 5,216 percutaneous transluminal angioplasties (PTA) and local thrombolysis were performed in the Department of Radiology of the University of Freiburg and the Hochrheinklinik of Bad Säckingen. From 1984 to 1989, 5,216 patients were reviewed clinically, and, in 360 cases, angiographically. The short-term results were compared with the long term results (i.e. 2 to 8 years after PTA or local lysis). The (stage IIb to stage IV) occlusive disease was treated by PTA. A successful PTA result was obtained in stage IIb in 73% of cases, in stage III in 68% of cases and, in stage IV in 36% of cases after 2-8 years including all regions of treated arteries. Complications occurred in 2.51% of cases. Over the last 2 years, dilatations, local thrombolysis and even intraluminal stent implantations can be controlled by ultrathin angioendoscopes.
Deep Neural Networks on Mobile Healthcare Applications: Practical Recommendations

Field: Health Professions (Health Sciences)

Deep learning has for a long time been recognized as a powerful tool in the field of medicine for making predictions or detecting abnormalities in a patient’s data. However, up until recently, hosting of these neural networks has been relegated to the domain of servers and powerful workstations due to the vast amount of resources they require. This trend has been steadily shifting in the recent years, and we are now beginning to see more and more mobile applications with similar capabilities. Deep neural networks hosted completely on mobile platforms are extremely valuable for providing healthcare services to remote areas without network connectivity. Yet despite this, there is very little information regarding the migration process of an existing server-based neural network to a mobile environment. In this work, we describe the various techniques and considerations that should be taken into account when developing a deep-learning enabled mobile application with offline support. We illustrate the above by providing a concrete example through our experience in migrating to mobile an in-house developed medical application for detecting early signs of traumatic brain injuries.
Assessment of Antibacterial Activity of Antibiotics and Monitoring of Drug-resistance in Recent Years

Field: Medicine (Health Sciences)

OBJECTIVE: Evaluating the antibacterial activity of antibiotics and monitoring drug-resistance METHODS:The drug-resistance was detected on 184 strains of bacteria isolated from clinical specimens during the period 1994～ March,1998 and in vitro antibacterial activities of 11 antibiotics were evaluated. RESULTS: Ceftriaxone and cefoperazo, amikacin ex-hibited high antibacterial activities (low rate of drug resistance)against E. coli and P. aeruginosa , respectively, but the antibac-terial activities of ceftriaxone , cefazolin against S. aureus , and that of norfloxacin against E . coli were decreased. CONCLUSION:Antibiotics should be selected according to the test results.
Universities as sites of nation-building: Rethinking the role of higher education in post-colonial state formation in India

Field: Social Sciences (Social Sciences)

This paper examines the role of universities in post-colonial nation-building, using India as a case. Moving beyond the conventional view of universities in postcolonial contexts as mere extensions of the developmental state, the paper argues for a decentralized understanding of their role in the process of nation-building. Drawing on the spatial turn in sociology, particularly Jeff Malpas’s conceptualization of place as a bounded yet dynamic opening shaped by intersecting forces, the paper conceptualizes universities as active, contested sites where meanings of nationhood, modernity, and identity are continuously constructed and negotiated. Through an analysis of the Indian Institute of Management Ahmedabad (IIMA), established in 1962, the paper explores how this institution became a pivotal site for constructing a particular postcolonial vision of Indian modernity during the 1960s. Delving into the complex negotiations and the influence of diverse actors and stakeholders, the study traces how a specific sociotechnical imaginary of management science—blending American models with Indian modernization aspirations—was embedded in IIMA’s curriculum, selection processes, and campus design. By foregrounding universities as co-producers of national imaginaries rather than passive instruments of state policy, this paper underscores the importance of recognizing the agency of universities in nation-building processes.
Comparison of cracking kinetics for Kern River 650{degrees}F{sup +} residuum and Midway Sunset crude oil

Field: Chemical Engineering (Physical Sciences)

Kern River 650{degrees}F{sup +} residuum and Midway Sunset crude oil were examined by micropyrolysis at several constant-heating rates to determine pyrolysis cracking kinetics. Determined by the discrete distribution method, both feeds exhibited principal activation energies of 50 kcal/mol and frequency factors {approximately} 10{sup 13} sec{sup -1}. Energy distributions were similar ranging from 45 to 57 kcal/mol. Determined by the shift-in-T{sub max} method, E{sub approx}, A{sub approx} for Kern River 650{degrees}F{sup +} and Midway Sunset were 48 kcal/mol, 1.3 X 10{sup 12} sec{sup -1}, and 46 kcal/mol, 4.6 X 10{sup 11} sec{sup -1}, respectively. These results are similar, but not identical to other kinetic parameters for heavy oils from type II source rocks.