jimnoneill/paper-to-field-training huggingface dataset:
Theoretical and practical aspects of social sphere management in the Yamalo-Nenets Autonomous Okrug

Field: Social Sciences (Social Sciences)

This article discusses social management challenges in Arctic region, using the example of existing social issues in the cities of the Yamalo-Nenets Autonomous Okrug. The theoretical concept is based on the authors' ideas, who postulate rational management principles, the evolutionary transformation of modern society principles that imply the mutual influence of economic and social factors. In additional, this concept advocates the importance of humanization and harmonization of public relations, the significance of the human factor, and citizens' initiatives. Improving the social sphere in the northern region can be achieved through successful business practices and implementing market mechanisms that balance state, public, and private interests. The article argues that optimizing managerial regulation in the region's social sphere is based on well-established legislative practice of social welfare. An analysis of scientific literature, along with qualitative and quantitative empirical research, uncovered the most pressing social issues in the region. This analysis led to insights about the current state of the social sphere in the Yamalo-Nenets Autonomous Okrug and helped identify strategies to optimize management approaches that aim to enhance public trust in government authorities. The interpretation of primary sociological data allowed to highlight critical areas for socio-economic development in the region's cities, such as healthcare, education, housing affordability, rising utility prices, and access to consumer goods. The survey results revealed respondents' priorities, which included health, family, financial stability, employment, etc. Furthermore, the survey results underscored the necessity of considering public opinion on enhancing social infrastructure and establishing continuous feedback with residents regarding vital socio-economic development sectors in cities. In conclusion, the study emphasizes the importance of improving socially-oriented managerial efforts and adopting principle of integrity that considers both economic and social indicators. These indicators enhance overall satisfaction with the quality of public services, including medical, educational, and other services. Only a comprehensive strategy for addressing social challenges is crucial for fostering public well-being, improving human capital, and optimizing the social sphere in the region.
Evolution des végétaux aquatiques dans les cours d'eau recalibrés (exemples pris dans le sud-ouest de la France)

Field: Agricultural and Biological Sciences (Life Sciences)

The maintenance of the streams examined now consist of clearing the areas invaded by helophytes or silted. Its effect is to restore the hydrosere to its original state. The succession can develop again as long as the growth of vegetation along the banks does not cut out too much incident light.
Metagenome-assembled genomes of three Hepatoplasmataceae provide insights into isopod-mollicute symbiosis

Field: Immunology and Microbiology (Life Sciences)

The digestive organs of terrestrial isopods harbor bacteria of the recently proposedmollicute family Hepatoplasmataceae. The only complete genome available for Hepatoplasmataceae is that of “Candidatus Hepatoplasma crinochetorum”. The scarcity of genome sequences has hampered our understanding of the symbiotic relationship between isopods and mollicutes. Here, we present four complete metagenome-assembled genomes (MAGs) of uncultured Hepatoplasmataceae members identified from shotgun sequencing data of isopods. We propose three novel species “Candidatus Tyloplasma littoralis” identified from the semiterrestrial isopod Tylos granuliferus, “Candidatus Hepatoplasma vulgare” identified from the common pill bug Armadillidium vulgare, and “Candidatus Hepatoplasma scaber” identified from the common rough woodlouse Porcellio scaber. Phylogenetic analysis of 16S ribosomal RNA sequences showed that “Candidatus Tyloplasma littoralis” and other semiterrestrial isopod-associated mollicutes form a sister clade to terrestrial Hepatoplasma members, justifying their assignment to a novel genus. Phylogenomic analysis of 151 mollicutes confirmed that Hepatoplasmataceae is a sister clade of Metamycoplasmataceae in the order Mycoplasmoidales. Our analysis also revealed that that Hepatoplasmataceae lack major metabolic pathways but has a likely intact type IIA CRISPR-Cas9 machinery, indicating that these mollicutes have an ectosymbiotic lifestyle with high nutritional dependence on their host. We did not find any evidence that Hepatoplasmataceae encode digestive enzymes that could provide nutritional benefits to the host, which suggests that they may act as defensive symbionts.
Parenting, perceived control, and symptoms of depression and anxiety in deaf youth

Field: Psychology (Social Sciences)

Deaf youth are at least six to eight times more likely to develop depression or anxiety compared to hearing youth. Decades of empirical evidence continue to suggest parent child-rearing practice and perceived control to be shared etiological factors for anxiety and depression in hearing youth. Deaf youth are at risk for lower perceived control and higher parental control compared to hearing youth. Despite evidence of heightened risk factors and poorer outcomes, associations between parenting, perceived control, and depression and anxiety have not been explored in deaf youth. The proposed quantitative study will explore these associations while controlling for age, sex, and additional disability. Results can inform appropriate intervention models for deaf youth.
Construction of a novel disulfidptosis-related signature for improving outcomes in hepatocellular carcinoma: Observational study

Field: Medicine (Health Sciences)

Disulfidptosis is a novel form of metabolic-related regulated cell death (RCD) that is caused by disulfide stress caused by the accumulation of excess cystine in the cell. Targeting disulfide metabolism imbalance is an emerging strategy for the treatment of cancer. However, it is undetermined how disulfidptosis-related genes (DRGs) influence hepatocellular carcinoma (HCC). Unsupervised clustering analysis was performed on the TCGA-LIHC cohort to identify various phenotypes of disulfidptosis. GSVA was used to measure the activation of characteristic gene sets, while CIBERSORT was employed to estimate the infiltration of immune cells. Disulfidptosis-related signature was generated to quantify the phenotype of disulfidptosis in HCC patients. Next, we examined the disparities among the high and low disulfidptosis score categories by considering clinical characteristics, infiltration of immune cells, functions related to the immune system, sensitivity to chemotherapeutic drugs, and effectiveness of immunotherapy. Two different disulfidptosis phenotypes with different prognoses, clinical traits, biological pathways, and immune cell infiltration were identified. Based on differently expressed genes (DEGs) among 2 disulfidptosis phenotypes, a disulfidptosis-related signature was built. The prognostic value of this signature was then evaluated in the TCGA and GEO datasets. Low disulfidptosis score indicated favorable clinical outcomes, higher levels of immune cell infiltration, lower tumor purity, and enhanced immune responses. Furthermore, we noticed a clear disparity in tumor mutation load and drug responsiveness when comparing the high and low disulfidptosis score categories. Finally, a quantitative nomogram was built with disulfidptosis score and several clinical characteristics. The disulfidptosis-related signature provides new insights into the tumor immune microenvironment and complexity in HCC. The disulfidptosis score can serve as a promising tool for personalized prognostic prediction of HCC patients and for customizing more effective immunotherapeutic strategies.
A Community Based Study on Awareness of HIV/AIDS among Young Males of Meerut, Uttar Pradesh

Field: Health Professions (Health Sciences)

Background: Acquired Immune Deficiency Syndrome (AIDS) is a challenging illness caused by the HIV virus, which weakens the immune system and leads to death through secondary infections. HIV/AIDS is spreading globally, hitting the younger generations. Objective: To assess the knowledge and awareness about HIV/AIDS among young males of rural and urban area of Meerut District. Study Design : Cross-sectional, community based study. Settings and Participants: One urban (Multan Nagar) and one rural (Khajuri) area under the field practice area of Department of Community Medicine, Subharti Medical College, Meerut. Sample Size: 600 male young males aged 15-24 years, 300 were selected from urban area and 300 from rural area respectively. Study Period: Jan 2011 to June 2011 Methodology: A pre-designed, pre-tested, interview schedule was used after taking verbal consent. Questions consisted of awareness (i.e. whether ever heard of HIV/AIDS), knowledge about source of infection, modes of prevention of HIV/AIDS and source of information regarding HIV/AIDS, Results: The awareness of HIV/AIDS was higher (80%) among the urban respondents as compared to the rural respondents (53.3%). The predominant source of information among urban respondents was reading material such as newspapers, magazine, brochure and electronic media and rural subjects was interpersonal communication with doctors, health workers and friends. 42.5% of the rural respondents and 16.7% urban respondents did not know about any source of infection of HIV/ AIDS. The predominant mode of transmission of HIV/AIDS which the maximum respondents knew was unsafe sex among both urban and rural area. 37.5% of the rural respondents and 16.7% urban respondents did not know about any modes of prevention for HIV/AIDS although 25% urban and rural respondents knew that condom usage prevents HIV infection. Conclusion: HIV/AIDS awareness and knowledge among the young males was found to be low. Targeted approach and more intensified Information, Education and Communication (IEC) campaigns are needed to contain this dreaded epidemic.
710 - Improving pediatric atopic dermatitis care: online intervention in the Deep South

Field: Health Professions (Health Sciences)

Abstract Introduction/Background Atopic dermatitis (AD) affects about 9.6 million children in the United States (US) under the age of 18. Most of these young people have moderate-to-severe AD symptoms, which have a significant negative impact on their own and their families' quality of life. Preventing triggers, repairing the skin's protective layer, and reducing inflammation are the main goals of effective AD treatment. Even though medical experts play a crucial role in teaching parents about managing AD, many caregivers struggle to follow treatment plans, which results in preventable flare-ups. Objectives The purpose of this study was twofold: firstly, to assess the efficacy of an intervention aimed at enhancing healthcare professionals' confidence and practices in managing AD; and secondly, to pinpoint areas for improvement to better assist parents in navigating their children's chronic illness. Methods The study involved the recruitment of 37 healthcare workers from a large university medical center located in the deep South of the United States using email and word-of-mouth. The medical professionals watched a 20-minute YouTube movie, conducted an online pre-test survey, and then completed an online post-test survey. Results The majority of participants (68.6%) identified as female, and the largest racial group was White (59.4%). The participant pool encompassed residents, fellows, or trainees (40.5%), physicians (37.8%), and advanced practice providers (10.8%), with an average age of 39.74 years. The findings indicated an improvement in participants' confidence to prescribe new therapies and educate patients about self-management behaviors for AD. Additionally, more respondents felt capable of offering resources to aid their patients' self-management and mobilizing social support for this purpose. Conclusions In the era of new targeted therapies, this online intervention presents an opportunity to bolster healthcare professionals' confidence and refine their practices in managing AD, potentially yielding enhanced outcomes for children and their families.
A Guide to Dermahistopathology

Field: Medicine (Health Sciences)

Journal Article A Guide to Dermahistopathology Get access A Guide to Dermahistopathology. By Pinkus Hermann and Mehregan Amir H.. New York: Appleton-Century-Crofts Division, Meredith Publishing Co., 1969. 546 pp. $20.00. Elson B. Helwig Elson B. Helwig Washington, D. C. Search for other works by this author on: Oxford Academic Google Scholar American Journal of Clinical Pathology, Volume 55, Issue 3, 1 March 1971, Page 389, https://doi.org/10.1093/ajcp/55.3.389a Published: 01 March 1971
The Effect of an Educational Curriculum Using the Hanging Ball Device in Learning the Skills of the Smash Serve and the Smash Hit in Volleyball

Field: Arts and Humanities (Social Sciences)

The aim of the research: The educational curriculum has been prepared by using a ball hanging device, the research under, covers the impact of using that device during (serves and spike) skills in Volleyball and compares it with the coach’s program. The researcher showed the significant difference between pre-test and post-test experiments for the educational curriculum. The researcher dissects the similar study that is relative to the new study like the concept of training skill learning. The researcher has used the experimental approach for its relevance to the nature of research. While using the two-group experimental design, one of them is experimental group and the other is control group. the program has been applied on a young volleyball team (Hawler sport club) (2017-2018). The subjects consist of 20 players divided by two groups (experimental and control) randomly each group consists of 10 players. After these steps the researcher was able to find Homogeneity and equivalence in the research subjects. In addition to using the tools and training equipment with research devices while working on the research; several tests took place, some concerning physical ability and some concerning motion. Then the researcher applied the main program for a duration of 6 weeks that consisted of three educational units per week. Each educational unit took a period of 90 minutes. Then the concluding experiment took place. In the end with the help of these experiments the researcher came up with these results. The researcher concluded the following: - The effect of the teaching program with the usage of the ball hanging device to learn skills such as (serve and spike) are positive for beginner players in Volleyball. - The results of the experimental group who carried out the teaching program by using the ball hanging device, came out superior over the control group in both (serve and spike) skills. -The researcher’s best recommendation and advice is while different branches of Physical education applying the educational curriculum they should consider using educational materials. Also, execute researches such as this one in, for different ages, and for both genders.
Inhaled insulin for the treatment of diabetes: projects and devices

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

A non-invasive alternative to insulin injections would represent a major improvement for Type 1 and 2 insulin-treated patients. The lung is the only route which allows bio-availability of insulin, approaching 10% without absorption enhancers. However, the reproducibility of the plasma response to the pulmonary insulin is similar to subcutaneous insulin analogues, that is to say, relatively poor. In the Exubera Project, the device is a dry powder inhaler. The insulin powder (Aventis) is packaged into a single dose blister containing 1 or 3 mg; the 1 mg blister corresponding to ∼ 3 U of insulin. Phase II studies have shown similar efficacy than regular insulin. Data are available on 328 Type 1 and 309 Type 2 patients after 6 months of Phase III trials. The inhaled insulin group developed increased insulin antibodies. A total of 25% of the patients experienced cough after inhalation. The number of overall and severe hypoglycaemic episodes were similar in the two groups. Pulmonary function tests remained stable and normal except for minor reductions of carbon monoxide diffusion capacity. The AERx IDMS system is a microprocessor-controlled, aqeous mist inhaler. The insulin (regular 100 U/ml, Novo Nordisk) is delivered by 1 U increments. The clinical experience reported with this system so far is limited to 107 Type 2 insulin-treated patients. The results are similar to those obtained in the Exubera trials. In the Alkermes project, large, porous, regular insulin of low-mass density have been developed by the Advanced Inhalation Project. Results from human studies in normal subjects show similar pharmacokinetics as the two other devices above. Other projects seem less advanced than the projects cited above e.g., Aerodos and Oralin. Current clinical experience with inhaled insulin seems promising. It represents currently the only viable non-invasive alternative to insulin injections. However, long-term local tolerance of the pulmonary tissue is a crucial issue.
Skills and qualifications mismatch phenomenon: focus on human capital in the global measurement

Field: Social Sciences (Social Sciences)

The article examines the essence and significance of the phenomenon of mismatch in skills and qualifications as a generalizing concept that combines all types of gaps and imbalances in skills and qualifications. Different types of this mismatch are considered. The factors that determine the spread of this phenomenon have been identified. The danger of widening the gaps in qualifications and skills, which manifests itself in the negative impact on the formation of qualitative characteristics of human capital and causes inefficiency in the use of its potential is substantiated. Through the prism of human capital, potential threats and global challenges caused by skills mismatches and their implications for society, employers and employees have been identified. Based on the analysis of increasing mismatch in skills and qualifications of workers, the formation of current trends in the global labor market has been examined; and these trends are: the existence of the so-called "post-pandemic hiking workers freezing syndrome" as an imbalance between supply and demand for jobs provoked by the COVID-19 pandemic; deepening the mismatch between the level of working people education and the jobs they occupy, indicating a significant global gap between education and employment. Possible ways to overcome skills and qualifications mismatches include strengthening the role of employers in deciding this issue and using the Future Skills Architect practical set of instruments, where the key indicator is the country's maturity index (FSA), which will enable governments of countries to form sets of quality solutions in the struggle for human capital.
Narrative in Medicine: The Stories of Elite College Athletes' Career-Ending Injuries

Field: Health Professions (Health Sciences)

A qualitative investigation of the illness experience of injured elite collegiate athletes illustrates the relevance of narrative to clinical practice. The article demonstrates a method for systematically assessing illness narratives and provides evidence that story patterns of clinical significance result. By adding a narrative approach to the biomedical one, it is argued, both the psyche and the pathophysiology of the sufferer can be the subjects of healing.
Icariside II promotes osteogenic differentiation of bone marrow stromal cells in beagle canine.

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Icariside II (ICS II) is a prenylated active flavonol from the roots of epimedium koreanum Nakai, and has many biological activities, including anti-osteoporosis, anti-hypoxia and anti-cancer activities. In this study, we aimed to study the effect of ICS II on osteogenic differentiation of bone marrow derived stromal cells (BMSCs). Cell surface markers of cultured BMSCs were analyzed by flow cytometry and identified by multi-lineage differentiation assays. BMSCs proliferation was determined by the cell counting kit-8 (CCK-8) assay for 2, 4, 6 and 8 days in a range of ICS II concentrations. The osteogenic response of BMSCs to ICS II in vitro was examined by alkaline phosphatase (ALP) activity assay and Alizarin red staining on calcium nodule formation. Results showed ICS II significantly improved ALP activity, and calcium deposition. The optimal concentration of ICS II for enhancing osteogenic differentiation of BMSCs was 10(-5). Therefore, we concluded ICS II can enhance the osteogenic differentiation of BMSCs which may be useful in clinic.
Privacy in personal care homes in Winnipeg, Manitoba as experienced by residents

Field: Health Professions (Health Sciences)

The case study examined physical and social privacy for nine residents residing in personal care homes in Winnipeg, Manitoba, Canada. The study explored how residents’ well-being and quality of life was affected by the privacy afforded to them in various room accommodations. The case study explored residents’ social location, room preference, safety and security, communication with family, interaction with staff, and interaction with roommates. The study found that residents benefit from having access to locks for doors; specialized units for cognitively impaired residents; private health assessment rooms; phasing out multi-bed room; use of room barriers; privacy for intimacy; access to private lounges for visiting; and private room with a public telephone. The study assists health care providers and students in health fields in becoming aware of privacy issues. The study may be useful in assisting residents to prepare for adjustment to a personal care home.