jimnoneill/paper-to-field-training huggingface dataset:
Prospective study of the value of serum chromogranin A or serum gastrin levels in the assessment of the presence, extent, or growth of gastrinomas

Field: Medicine (Health Sciences)

BACKGROUND Serum chromogranin A levels (CgA) are reported by some authors to be of clinical utility for assessing the presence or absence of a pancreatic endocrine tumor and tumor extent or growth. The aim of the current study was to assess this finding and compare the results with those from serum gastrin determinations (FSG) in a large cohort of patients with gastrinomas. METHODS In 112 consecutive patients with the Zollinger–Ellison syndrome serum CgA and FSG levels were measured and correlated with disease activity, extent of disease, and the presence of multiple endocrine neoplasia type-1 (MEN-1) or gastric carcinoid tumors. RESULTS Serum CgA levels drawn on 2 consecutive days correlated closely (P < 0.00001) as did serum gastrin levels. Serum CgA levels correlated significantly with FSG levels (P < 0.00001). Serum CgA and FSG levels were significantly higher in patients with active disease than in disease free patients (P < 0.00001). The sensitivity for the presence of disease was higher for CgA compared with FSG (92% vs. 80%; P = 0.021). However, the specificity of CgA was 67%. Serum CgA levels were not significantly different in the four disease categories (stable extrahepatic disease, increasing extrahepatic disease, stable liver metastases, and increasing liver metastases). FSG levels were significantly lower in patients with stable extrahepatic disease compared with those with increasing extrahepatic disease. However, both tumor markers decreased significantly with a gastrinoma resection in five patients. The presence of MEN-1 or a gastric carcinoid tumor did not influence the results. CONCLUSIONS The results of the current study showed that serum CgA and FSG levels both are sensitive tumor markers for the detection of a gastrinoma; however, CgA levels have a relatively low specificity. Neither the magnitude of the serum CgA nor gastrin level correlated with tumor growth or tumor extent and therefore cannot be used to determine these variables. However, in contrast to some other studies, the results of the current study show that changes in serum CgA or gastrin in a given patient with time are related to the tumor extent and not to gastric mucosal changes due to hypergastrinemia. Cancer 1999;85:1470–83. © 1999 American Cancer Society.
Clinical Scoring Systems in the Newborn Calf: An Overview

Field: Veterinary (Health Sciences)

A scoring system is an instrument that enables the scorers, including farmers, technicians, and veterinarians, to adopt a systematic approach for diagnosis or monitoring, as it decreases bias and confounding and increases objectivity. Practically, it is a number assigned to a patient that correlates with a probability that a diagnosis can be confirmed or that a specific outcome will follow. This article examines the clinical scores designed or adapted to bovine medicine that aim to assess newborn calf viability and to diagnose and monitor neonatal calf diarrhea and respiratory diseases, helping the clinician promptly recognize calves needing medical assistance. Despite the large number of clinical scores described in the literature, these are still barely used in farm animal practice; possibly, the complexity of the scores and missing recommendations for intervention are reasons for their lack of popularity as well as the crosswise lack of consistency among scores designed for the same purpose. Further research is needed in this regard to increase scores validation and encourage their application in bovine calf neonatology.
Isolation of human genital TRIC agents in nongonococcal urethritis and Reiter's disease by an irradiated cell culture method.

Field: Medicine (Health Sciences)

In an earlier study, Ford and McCandlish (1969) isolated TRic agents, by the yolk-sac method, from fifteen of 133 urethral scrapings of men with non- gonococcal urethritis.Gordon and Quan (1965) had previously found that TRIC agents would propagate in irradiated McCoy cells and could be readily demon- strated by the resulting inclusions which stained purple with iodine because of their glycogen content.Subsequently, Gordon, Harper, Quan, Treharne, Dwyer, and Garland (1969) considered that the McCoy cell method was more sensitive in addition to being quicker and more convenient than the yolk-sac method in isolating TRic agents from clinical specimens.It therefore seemed advisable to perform an evaluation of the two methods in Vancouver and the following paper describes our results.
CSDC2, a cold shock domain RNA‐binding protein in decidualization

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

RNA‐binding proteins (RBPs) have been described for cancer cell progression and differentiation, although there is still much to learn about their mechanisms. Here, using in vivo decidualization as a model, we describe the role of RBP cold shock domain containing C2 (CSDC2) in the endometrium. Csdc2 messenger RNA expression was differentially regulated depending on time and areas of decidua development, with the most variation in antimesometrium (AM) and, to a lesser degree, in the junctional zone (JZ). Immunohistochemistry of CSDC2 showed a preferentially cytoplasmic localization at AM and JZ, and nuclear localization in underneath myometrium and mesometrium (M). Cytoplasmic localization coincided with differentiated, DESMIN‐marked areas, while nuclear localization coincides with proliferative zones. Uterine suppression of CSDC2 through intrauterine‐injected‐specific small interfering RNA (siRNA) led to abnormal decidualization in early pregnancy, with more extended antimesometrial area and with poor M development if compared with control siRNA‐injected animals. These results suggest that CSDC2 could be a regulator during decidua development.
More ways to mold profits

Field: Chemical Engineering (Physical Sciences)

RETURN TO ISSUEPREVAdvertisementNEXTMore ways to mold profitsCite this: Chem. Eng. News 1962, 40, 13, ibc–ibc-aPublication Date (Print):March 26, 1962Publication History Published online6 November 2010Published inissue 26 March 1962https://doi.org/10.1021/cen-v040n013.ibcCopyright © 1962 American Chemical SocietyArticle Views54Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alerts
GROWTH AND CHEMICAL COMPOSITION OF CORN IN THREE CALCAREOUS SANDY SOILS OF IRAN AS AFFECTED BY APPLIED PHOSPHORUS AND MANURE

Field: Agricultural and Biological Sciences (Life Sciences)

Phosphorus (P) fertilizer recommendations for calcareous-sandy soils low in organic matter need further investigation. Therefore, the objectives of this study were to evaluate the effects of P and manure on corn (Zea mays L.) growth and chemical compositions and P recommendations for calcareous sandy soils with low organic matter under greenhouse conditions. Treatments consisted of a factorial arrangement of P levels (0, 25, 50, and 100 mg kg -1 soil as KH2PO4), manure rates (0, 10, 20 and 30 g dried sheep manure per kg soil) and three soils (Soil 1, sandy loam, initial P 10.8 mg kg -1 ; Soil 2, sandy loam, initial P 7.6 mg kg -1 ; and Soil 3, loamy sand, initial P 5.5 mg kg -1 ) in a completely randomized design with four replications. Results showed that P application in Soil 1 decreased corn dry matter. However, application of 25 or 50 mg P kg -1 soil increased corn yield significantly in Soils 2 and 3, respectively. Maximum corn yield was obtained when 30 g kg -1 manure was added to sandy loam soils and 20 g kg -1 to loamy sand soil. Application of P and manure significantly increased plant P concentration and uptake in all three soils. Zinc concentration in plants treated with Phosphorus was higher than in the control in soils 1 and 2. Such a trend was not observed in soil 3, but manure application increased it. Iron concentration in plants treated with P increased in soils 1 and 2 but was decreased in soil 3; however, manure application increased it in all soils. Plant Mn concentration and uptake responses to P and manure application was not consistent. Applied P, in general, increased plant Mn Concentration in soils 1 and 2, but had no effect on plants in Soil 3. Manure effect on plant Mn concentration was not consistent. It seems that addition of manure to sandy soils can improve soil productivity and increase corn yield. Due to the low P buffering capacity of sandy soils, application of high rates of P can increase P concentration to an undesirable level in soil solution. This may depress plant growth and also availability of some micronutrients like Fe and Zn to corn plants. Therefore, P fertilizer recommendations for sandy soils should be based on the soil test P level. Manure application is recommended for sandy soils, due to its positive effects on nutrient uptake and plant growth. Prior to any phosphorus fertilizer recommendations for sandy soils the results of this experiment should be verified under field conditions and measuring P concentration in soil solution at different stages of plant growth is highly recommended.
Selected aspects of entering adulthood by adolescents with disabilities

Field: Social Sciences (Social Sciences)

The purpose of the publication is to present selected aspects of adult life in people with disabilities. Young adults, verifies their plans and goals and tries to fulfill the life tasks typical of this stage in a satisfactory manner. In specific situations (such as disability), meeting these challenges can be difficult: the process of becoming independent and taking up work may face a number of internal and external difficulties. The article refers to the four models of Marin Sińczuch's gaining independence.
Art in an age of reflection

Field: Arts and Humanities (Social Sciences)

In The Point of View for My Work as an Author Kierkegaard uses the concept of “the aesthetic” to establish one of the fundamental divisions of his authorship. Even more significantly, he seems to give to the question of whether the authorship is “aesthetic” or “religious” a pivotal place in defining the correct “point of view” from which to understand that authorship as a whole. We might therefore conclude that a concern with “the aesthetic” lies at the very heart of Kierkegaard's intellectual project.
THE SPECIFICITY OF THE BODY-CELL TOXINS.

Field: Medicine (Health Sciences)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Effect of high‐fat diet and growth stage on the diversity and composition of intestinal microbiota in healthy bovine livestock

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract BACKGROUND This study aimed to investigate the composition of bacteria in the bovine rectum and their functions during growth, in relation to different diets. Fecal samples were collected from 6‐, 12‐, 18‐ and 24‐month cattle fed high‐fat diet, and healthy female parents fed regular diet. Total DNA was amplified ( V3–V4 of 16S rRNA ) and submitted to barcode‐ DNA pyrosequencing. Intestinal microbiota profiles and functions were then analyzed. RESULTS A total of 114 512 operational taxonomic units were detected from the 1 802 243 sequences obtained. In 6‐month‐old and female parent groups, the top three abundant phyla were Bacteroidetes (37.6%, 32.2%), Firmicutes (34.4%, 48.2%) and Proteobacteria (9.1%, 6.3%); in the 12‐, 18‐ and 24‐month groups, they were Proteobacteria (45.5%, 47.1%, 38.8%), Firmicutes (27.4%, 22.2%, 20.1%) and Bacteroidetes (14.9%, 19.4%, 17.7%), respectively. Paludibacter and Desulfopila in abundance showed negative ( P < 0.001) and positive ( P < 0.05) correlation, respectively, to cattle weight gain through metagenomic functional prediction of methane, cysteine and methionine metabolism. Meanwhile, cofactor/vitamin and amino acid metabolic processes were significantly higher in bacteria from the regular diet group than high‐fat diet groups, with markedly lower cellular processes and signaling, and reduced glycan biosynthesis and metabolism ( P < 0.01). CONCLUSIONS The 6‐month cattle and female parents shared similar intestinal bacteria; the community structure of fecal microbiota was significantly affected by high‐fat diet in older cattle. © 2017 Society of Chemical Industry
Thermopower of a multiprobe ballistic conductor

Field: Physics and Astronomy (Physical Sciences)

The thermopower of a multiprobe ballistic conductor in the form of caterpillarlike Sinai billiard is experimentally investigated. The magnetic-field dependence of both longitudinal thermopower and Nernst-Ettingshausen effect exhibits commensurability oscillations, which are more pronounced than the corresponding oscillations in the magnetoresistance. Results of computer calculations based on the generalized Landauer-B\"uttiker approach are in agreement with experiment. The observed features in the thermopower originate from drastic difference between the transmission coefficients of quasielectrons (above the Fermi level) and quasiholes (below the Fermi level) in the vicinity of geometrical resonances.
Optimization of barley flour and inulin addition for pasta formulation using mixture design approach

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract The aim of the present work was to optimize the formulation of a new functional pasta containing durum wheat semolina, whole barley flour, and inulin ingredients to enhance both the technological and textural properties of this product using the mixture design approach. Optimally formulated pasta with acceptable technological and textural properties as close as possible to those of control pasta was studied. The microstructure analysis of cooked and uncooked pasta was performed. Cox response trace plots revealed that the increasing amounts of whole barley flour and durum wheat semolina resulted in an increase in the cooking quality parameters and yellowness. However, pasta firmness was negatively influenced by inulin and whole barley flour addition. The ingredient composition of the optimally formulated pasta, which leads to the best technological and textural properties, was 94.8% durum wheat semolina, 3.7% whole barley flour, and 1.5% inulin. This optimal formulation had an optimal cooking time of 335.24 s, a swelling index of 2.15%, and a cooking loss of 10.44%. The firmness values and the color parameters were also satisfactory. The microstructure of the optimally formulated cooked pasta showed the presence of few not gelatinized starch granules incorporated into the protein matrix as compared to the control pasta. Practical Application Three ingredients, durum wheat semolina, whole barley flour, and inulin, were used for the production of new functional pasta using a mixture design approach. The obtained optimally formulated pasta, with good technological and textural properties, was rich in several dietary fibers. This allows the application of whole barley flour and inulin in the cereal industry and can be of interest to the human diet.
[Renal abscess in childhood: a case report].

Field: Medicine (Health Sciences)

We describe the case of a previously healthy six-year-old boy with a right renal abscess due to a methicillin-resistant Staphylococcus aureus, which necessitated a radical nephrectomy. Although renal ultrasonography is often the initial tool to identify fluid collection, in our case the diagnosis was obtained only after performing an abdominal CT with intravenous contrast. It is therefore necessary to combine these different imaging techniques in all children with fever and abdominal/lumbar pain without any apparent cause in order to obtain an early diagnosis and minimise organ damage.
A Study on the Soot Suppression in a Hydrocarbon Turbulent Diffusion Flame by Corona Discharges

Field: Engineering (Physical Sciences)

The effects of DC or AC (14 kHz) corona discharges, formed between the apexes of opposed needle electrodes, on the soot emission of a propane turbulent diffusion flame were investigated experimentally. The coronas were applied across the lower part of the flame, where soot inception occurs, or across the middle part of the flame where both agglomeration and oxidation of carbon particles proceed. On application at the lower part, with a gap width as the electrode apexes are located outside the reaction zone, a marked reduction in soot emission was observed in cases of both DC and AC corona discharges, suggesting that this reduction is not caused by entrainment or corona wind alone. The charged particles, added to the flame, are mostly produced in the vicinity of the apexes of electrodes where maximum field strength exists. As for the mechanisms of the soot reduction, the increased charged-particle density observed in the middle and upper part of the flame seems to play a role.
"The graduate drug scene" : a study on highly educated drug users and media portrayal of drugs in Singapore

Field: Social Sciences (Social Sciences)

This research aims to understand the graduate drug scene in Singapore by understanding what causes highly educated individuals to want to take drugs. It also aims to explore the drugs taken by highly educated individuals, where they take these drugs and their attitudes towards drugs. The data in this paper was gathered through semi-structured interviews with respondents who were selected through non-random sampling methods. This research also aims to examine the profile of a drug user that the state attempts to create. In addition, the respondents were asked to give their opinions about the state created profile of drug users. The respondents were also asked about their opinions on how the variables of race, educational qualifications and social class impact drug usage.
Evaluation of pulmonary functions in patients of type-2 diabetes mellitus

Field: Medicine (Health Sciences)

Background: The review of literature revealed conflicting documentation regarding the effect of type-2 DM (diabetes mellitus) on pulmonary functions. Some authors have reported normal pulmonary functions and even concluded that spirometry testing is not at all necessary in diabetic patients. Some studies have shown abnormal pulmonary functions in patients of DM. Moreover, the duration of DM and glycemic control have varied impact on the pulmonary functions. The present study was undertaken to resolve the conflict and also to explore the pulmonary functions in type-2 diabetics of this cross section of population.Methods: The pulmonary function tests FVC, FEV1, FEV3, PEFR and MVV were performed in 50 type-2 diabetics and 50 controls by computerized medspiror using standard laboratory methods. The data was documented statistically analyzed. By giving suitable class intervals, intra-diabetic groups were made to assess the effect of extent duration of diabetics on pulmonary function test.Results: Pulmonary functions FVC, FEV1, FEV3 PEFR and MVV were decreased in type-2 diabetes mellitus. Duration of type 2 DM was significantly associated with decrease in FVC, FEV1%, PEFR and MVV.Conclusions: Longer duration of type 2 diabetes is significantly associated with reduction in pulmonary functions FVC, FEV1%, PEFR and MVV which underlines the respiratory system as one of the target organs of type-2 diabetes mellitus.
Chemical control of bacterial leaf blight of rice caused by Xanthomonas oryzae pv. oryzae

Field: Agricultural and Biological Sciences (Life Sciences)

Bacterial leaf bligh (BLB) of rice caused by Xanthomonas oryzae pv. oryzae (Uyeda & Ishiyama) is emerging as serious threat to worldwide Rice production including Pakistan and its control is becoming important. The present study was conducted to investigate the antibacterial activity of different broad spectrum antibiotics against the Xanthomonas oryzae pv. oryzae (Xoo) isolates through in vitro assays. BLB diseased samples, collected from various rice growing areas of Punjab region (eastern Pakistan), were provided by Fungal and Bacterial Diseases group, NIAB Faisalabad. Behavior of five virulent Xoo isolates was checked against six antibiotics namely Benzylpenicillin, Ampicillin, Kanamycin, Streptomycin, Chloramphenicol and Sinobionic in four concentrations i.e 31.2, 62.5, 125 and 500. Benzylpenicillin was found the best for isolate no. 21.3 and 17.1, Amplicillin for isolate no. 16.5 and Kanamycin for isolate no. 77.2 and 2.6. The present study shows that antibiotics can effectively control BLB disease in vitro.
Legal Challenges in the Global Financial Crisis : Bail-outs, the Euro and Regulation

Field: Social Sciences (Social Sciences)

The global financial and economic crisis which started in 2008 has had devastating effects around the globe. It has caused a rethinking in different areas of law, and has posed new challenges to regulators and private actors alike. One of the emerging issues is the apparent eclipse of boundaries between different legal disciplines: financial and corporate lawyers have to learn how public law instruments can complement their traditional governance tools; conversely, public lawyers have had to come to understand the specificities of the financial markets they intend to regulate. While commentary on financial regulation and the global financial crisis abounds, it tends to remain within disciplinary boundaries. This volume illustrates how interdisciplinary scholarship belongs at the center of any discussion of the economic crisis, and indeed regulation theory more generally. As a timely exploration of cutting-edge issues of financial regulation, the book brings together scholarship from different areas of law (constitutional and administrative law, EU law, financial law, and regulation), from a variety of backgrounds (academic, practitioner, and policy making), and from a number of different jurisdictions. It is a fascinating and thought-provoking study for anyone interested in how the global financial crisis has affected the law.