jimnoneill/paper-to-field-training huggingface dataset:
The quiet Western Front: the First World War and New Zealand memory

Field: Arts and Humanities (Social Sciences)

The story of the Great War and public memory is now much-trod, if contested, territory, and the title of this chapter picks up on some crucial markers of that debate. What is new is the application of these issues to New Zealand. In particular, we need to wrestle with the politics of a colony, or more exactly a dominion, of the British empire. This raises questions of cultural imperialism. As a result, the timing and the conclusions of the story are subtly different from the more familiar narrative in the old world.
Second Time Round: Fugal Memory in Ciaran Carson’s For All We Know

Field: Arts and Humanities (Social Sciences)

The influence of musical traditions on Ciaran Carson’s work has long been noted. Carson’s use of fugue forms, especially in For All We Know (2008), however, suggests a different, and perhaps more political, relation to form than can be found in his earlier collections. As can be seen with comparison to the work of Paul Celan, Carson uses fugue to navigate through what Pierre Nora calls the ‘fundamental opposition’ between memory and history. The doubling and repetition inherent to fugal forms provide a way to reconceptualise the past, highlighting the interrelation of multiple corresponding voices. Carson, like Celan, uses fugue to approach historical moments that resist language, and in so doing reconceptualises the demands the past makes on the present, and the ability of language to reflect those demands.
Tumor epitope detection in monocytes (EDIM) as a marker for antitumoral activity of Newcastle disease virus infusion and modulated electrohyperthermia

Field: Medicine (Health Sciences)

Active specific tumor vaccination with autologous dendritic cells is an emerging treatment strategy for several cancer types. Feasibility and lack of toxicity is demonstrated in numerous clinical trials. In order to improve the potency for the induction of effective tumor control, combination approaches are studied, including oncolytic virotherapy and modulated electrohyperthermia (mEHT), both inducers of immunogenic cell death (ICD). Patients (n = 24) were treated with daily infusions of Newcastle Disease Virus (NDV) and with mEHT as part of multimodal immunotherapy. Blood was followed with flow cytometry on a daily basis for change of two tumor epitopes in monocytes using the EDIM test: the DNaseX/Apo10 proteine epitope, a marker of abnormal apoptosis and proliferation, and Transketolase-like 1 (TKTL1), a marker for anaerobic glucose metabolism (Warburg effect). Patients were in median 54 years (range 3 – 79). Cancer categories were neuro-oncology (n = 11), urologic (n = 2), gynecologic (n = 5), digestive (n = 5) and pulmonary (n = 1) oncology. For all cancer types we found a significant increase in the score for Apo10, TKTL1 and the sum of both from the first till the sixth treatment. In 9 patients, we were able to follow the same variables during a second week of treatment, scheduled 3 weeks after the first. The scores were returned to the basic value, but again increased significantly upon daily NDV/mEHT treatment. The data demonstrate that NDV/mEHT target tumor cells, and induce ICD with release of Apo10 and TKTL-1, taken up by circulating monocytes and detected in EDIM test.
P-1131. Comparison of Vancomycin Use Before and After the Implementation of an Antimicrobial Stewardship Program in a Pediatric Reference Hospital in Mexico

Field: Health Professions (Health Sciences)

Abstract Background The growing threat of antimicrobial resistance is associated with the overprescription of broad-spectrum antibiotics. Antimicrobial stewardship programs (ASP) promote the responsible use of antibiotics. Their successful implementation requires adequate infrastructure and interdisciplinary efforts. ASPs in Mexico (Mx) are still scarce, particularly in pediatric centers. Table 1. Diagnostics that justified use of Vancomycin Total of diagnostics founded on 71 Stewardship Interventions Methods Ambispective study to compare Vancomycin (VA) use before-after implementing a pilot 9-month handshake (HS) ASP at the pediatric reference hospital in NL, Mx. Stewardship interventions were applied from Jan to Oct 2022 among patients &gt;1 mo and &lt; 16 yr hospitalized with clinical suspicion/confirmation of Gram-positive infection, candidates to receive or currently receiving VA. PID specialists performed morning HS rounds. Prescription was labeled as correct/incorrect according to IDSA guidelines. Interventions were stratified as VA prevention and early discontinuation. VA use (DOT/1000 PD) from Jan to Oct 2021 was compared with t-Student test and ANOVA.Table 2.DOT/1000 PD Pre and Post the 9-month Pilot Hand-Shake Stewardship Program Analysis of the DOT/1000 PD Compared of the Same Population at the Pediatric Reference Hospital in NL, Mx on a 9-month Period. Results A total of 92 stewardship interventions were applied. Of these, the incorrect use of VA was prevented before its prescription in 21 cases. VA prescription was incorrect in 46% of the cases, in which early discontinuation was ordered. Correct use of VA (54%) occurred in patients with meningitis (31.5%), CLABSI (21%), septic shock (13%), among others (Table 1). SA was isolated in 14 patients. MRSA prevalence was 35.7% (5/14). Both prevention and early discontinuation of VA led to a decrease of 5.2 DOT/1000 PD (8.2 vs 3.6 DOT/1000 PD) (p=0.06) (Table 2). Conclusion Implementing a HS ASP for 9 months in a pediatric reference hospital in Mx decreased the use of VA by 5.2 DOT/1000 PD. Although this was a short pilot program, implementing ASP reduced the use of broad-spectrum antibiotics. Extending the ASP duration may achieve lower VA use and statistical significance. The number of PID specialists in Mx is limited, which highlights the importance of ASP. Multidisciplinary efforts are required to reduce antimicrobial overuse. Disclosures All Authors: No reported disclosures
Adventure Education: Theory and Applications

Field: Social Sciences (Social Sciences)

Chapter 1. Introduction to Adventure Education Chapter 2. Philosophy and Theories of Adventure Education Chapter 3. Cornerstones of Adventure Education Chapter 4. Risk and Safety in Adventure Programming Chapter 5. Individual Outcomes of Participating in Adventure Chapter 6. Skills for Adventure Activities Chapter 7. Facilitating the Adventure Process Chapter 8. Games, Initiatives and Activities Chapter 9. Low Element Courses Chapter 10. High Element Challenge Courses Chapter 11. Facilitating Outdoor Adventure Pursuits Chapter 12. Adventure Programming in Different Settings and Career Paths.
Robbing Students of Future Earnings and America’s Economic Growth: The Lack of Financial Literacy Courses in Public Schools

Field: Social Sciences (Social Sciences)

This study evaluates the benefits and opportunities of a high school financial literacy course mandate. Growing American credit card debt and personal bankruptcies have demonstrated a need for financial literacy. This knowledge would empower individuals to have better credit management and budgeting practices, more favorable loans/interest rates, and the ability to grow their wealth. An analysis of interest rate distribution, financial literacy surveys, and the success of other financial education methods have shown the potential return and benefits in the long run for high school graduates of just a single semester course. Data from the Brooking Institute and Harvard Business School has proven that financial education taught at a younger age results in greater economic stability. Therefore, students who take a personal finance course will be less reliant on welfare programs and contribute more to society. With the apparent financial disparities in education and wealth across many groups, high school presents a unique opportunity to address most students before their paths diverge effectively.
NGC 6709: A Faint Zero-Age Main Sequence Open Cluster

Field: Physics and Astronomy (Physical Sciences)

Gyrochronology is the study of stellar spin down with respect to age. Open clusters contain mostly homogenous stars and thus are ideal to calibrate the dependence of rotation rates on stellar mass and age. We select for this study NGC 6709, a young open cluster (∼ 150 Myr) with at least one red giant member that is similar in age to the Pleiades. We take a series of observations from May 2015 to June 2018 with the AIP’s STELLar Activity 1.2m telescope (STELLA1) and apply the point spread function to construct individual time series for 305 cluster members in our field. We search for periods within the time series utilizing four data analysis techniques: the phase dispersion minimization method, the string length method, the generalized Lomb-Scargle method, and the CLEAN method. Of the 305 cluster member stars, periods are recovered for the photometric light curves of 60 stars. We plot the Gaia colors of these stars against their periods to obtain a color-period diagram (CPD). The CPD has two main features: a sequence of slow rotators that fall along a diagonal where period increases with redder stars, and a less populated clump of rapidly rotating cool stars. The area between these two regimes is sparsely populated. We compare the results to several gyrochronology models of stellar spin down by using isochrones. The bifurcation of rotation periods is explained by the transition of stars between rapid and slow rotation as they spin down over time. The CPD of NGC 6709 is similar to those of clusters with ages around 110–160 Myrs, such as the Pleiades and NGC 2516, demonstrating consistency in stellar rotation, activity, and age across different clusters.
Polarized frequency combs in a mode-locked VECSEL

Field: Physics and Astronomy (Physical Sciences)

In this paper, we present a detailed and rigorous derivation of the delay differential equations of the spin-flip model for vertical external cavity lasers with a semiconductor saturable absorption mirror. This model describe mode-locked semiconductor lasers in the ring-resonator geometry with unidirectional lasing. This contribution completes a previous communication [Vladimirov et al. Opt. Lett., 45, 252 (2020)], and we further complete the analytical derivation by taking into account phase and amplitude anisotropies and the resulting different delay times for orthogonal linear polarizations. We show evidence of the coexistence of two linearly polarized frequency combs generation with slightly different repetition rates due to the birefringence-induced time-of- flight difference.
Local governance and regional development: An introduction to the special edition of AJRS and strategic directions for research

Field: Social Sciences (Social Sciences)

In December 2015 the Australia and New Zealand Regional Science Association International (ANZRAI) held its 39th Annual Conference at the University of Technology Sydney. Prior to the conference the Editorial Board of Australasian Journal of Regional Studies (AJRS) and the Executive of ANZRAI agreed to a Special Edition (SE) of the journal entitled 'Local Governance and Regional Development' to be developed and published as part of the outcomes of the conference. In this 'Introduction' the members of the ad hoc Editorial Board formed for the SE provide an account of the conference and a concise overview of the papers therein as they relate to the theme of 'Local Governance and Regional Development'. We also reflect upon the strategic directions for research in regional studies.
WDM and ETDM for future optical transmission systems

Field: Engineering (Physical Sciences)

Possible approaches to satisfy the increasing demand of transmission bandwidth are electrical time-division multiplex (ETDM) and wavelength-division multiplex (WDM). This contribution covers major aspects of those systems. Experimental results are presented for a 40 Gbit/s ETDM system and a 32/spl times/20 Gbit/s WDM system.
Incomplete Disclosure of Potential Conflicts of Interest

Field: Medicine (Health Sciences)

Charles E. Edmiston Jr, PhD; Cheong J. Lee, MD; Candace J. Krepel, MS; Maureen Spencer, MEd; David Leaper, MD; Kellie R. Brown, MD; Brian D. Lewis, MD; Peter J. Rossi, MD; Michael J. Malinowski, MD; Gary R. Seabrook, MD
Analysis of the impact of the information society on the Arab world through the perspective of university professors at Mentouri University of Constantine in Algeria

Field: Social Sciences (Social Sciences)

The information society has had many influences on the Arab cultural identity, forming ethical dimensions in its content, which have greatly and directly affected the Arab cultural system, which, according to the comprehensive plan for Arab culture prepared by the Arab League for Education, Culture and Science, consists of language, education, media, creativity, in addition to the system of Values, beliefs, and the thought of culture, which is considered an essential element in its system and is linked to the rest of the elements of the cultural system, which interact with each other in an endless series of influence and influence process, such that it is impossible to separate any element of it from the rest of the elements. No matter how different the elements of culture are, they stem from cultural identity. Which represents an acquired and inherited cultural model, stemming from historical, natural, human, and cultural constants and variables, which is characterized by relative stability. Cultural identity can be described as the driving element that allows the nation to pursue creativity and development while preserving its special cultural components and collective features, which is a challenge in... The information society, considering globalization as one of its clearest characteristics. Perhaps one of the most prominent features of globalization is what appears to us through the amazing developments witnessed in the fields of communication and communication via satellites, computers, and the Internet, which are considered among the most important characteristics of the information society.
Target Gene Prediction of Transcription Factor Using a New Neighborhood-regularized Tri-factorization One-class Collaborative Filtering Algorithm

Field: Computer Science (Physical Sciences)

Identifying the target genes of transcription factors (TFs) is one of the key factors to understand transcriptional regulation. However, our understanding of genome-wide TF targeting profile is limited due to the cost of large scale experiments and intrinsic complexity. Thus, computational prediction methods are useful to predict the unobserved associations. Here, we developed a new one-class collaborative filtering algorithm tREMAP that is based on regularized, weighted nonnegative matrix tri-factorization. The algorithm predicts unobserved target genes for TFs using known gene-TF associations and protein-protein interaction network. Our benchmark study shows that tREMAP significantly outperforms its counterpart REMAP, a bi-factorization-based algorithm, for transcription factor target gene prediction in all four performance metrics AUC, MAP, MPR, and HLU. When evaluated by independent data sets, the prediction accuracy is 37.8% on the top 495 predicted associations, an enrichment factor of 4.19 compared with the random guess. Furthermore, many of the predicted novel associations by tREMAP are supported by evidence from literature. Although we only use canonical TF-target gene interaction data in this study, tREMAP can be directly applied to tissue-specific data sets. tREMAP provides a framework to integrate multiple omics data for the further improvement of TF target gene prediction. Thus, tREMAP is a potentially useful tool in studying gene regulatory networks. The benchmark data set and the source code of tREMAP are freely available at https://github.com/hansaimlim/REMAP/tree/master/TriFacREMAP.
MOS Capacitance-Voltage Characteristics from Electron-Trapping at Dopant Donor Impurity

Field: Physics and Astronomy (Physical Sciences)

The capacitance versus DC-voltage formula from electron trapping at dopant impurity centers is derived for MOS capacitors by the charge-storage method. Fermi—Dirac distribution and impurity denization are included in the DC-voltage scale. The low-frequency and high-frequency capacitances, and their differences and derivatives, are computed in the presence of an unlimited source of minority and majority carriers. The results show that their difference and their DC-voltage derivatives, are large and readily measurable, hence suitable as a method for characterizing the electronic trapping parameters at dopant impurity centers and for a number of lower power signal processing and device technology monitoring applications.
Applying theory and research toward reducing suicidality among graduate students and postdoctoral scholars

Field: Psychology (Social Sciences)

Purpose The purpose of this paper is to highlight suicide risk factors experienced by graduate students and postdoctoral scholars, and then outline suicide prevention strategies for these populations. Design/methodology/approach Through analysis of literature and application of theory, the authors use the diathesis-stress model and Joiner’s (2005) interpersonal theory of suicidality to outline suicide prevention strategies specific to graduate students and postdoctoral scholars. Findings The authors’ review of the literature and application of theory suggest that both individuals and groups can engage in suicide prevention strategies, specifically pertaining to reducing stressors unique to graduate students and postdoctoral scholars, as well as addressing feelings of thwarted belongingness and perceived burdensomeness that can lead to the development of suicidality within these populations. Practical implications Engaging in suicide prevention strategies can save lives and address the mental health conditions exhibited among graduate student and postdoctoral scholars. Originality/value The authors offer a synthesis of good practices addressing suicide risk factors and prevention with attention to the stress-diathesis model and Joiner’s (2005) interpersonal theory of suicidality toward reducing suicidality among graduate students and postdoctoral scholars.
Governing knowledge sharing behaviour in post-Soviet Kazakhstan

Field: Business, Management and Accounting (Social Sciences)

Purpose The purpose of this study is to expand the understanding of knowledge governance approaches by examining governance mechanisms that can be used to enhance affective commitment. Then, this paper aims to investigate the mediating effects of affective commitment on the relationship between knowledge governance mechanisms (KGMs) and knowledge sharing. Design/methodology/approach Self-administered questionnaires were used to gather data from 391 employees working in a wide range of organizations operating in Kazakhstan. Regression analysis and structure equation models (SPSS and AMOS) were used to assess the research model. Findings The empirical results indicated that formal and informal KGMs have a significant impact on knowledge sharing. Moreover, the results revealed that affective commitment mediates the relationship between KGMs and knowledge sharing. Practical implications The proposed KGM is a response to practical necessity to promote the affective commitment by combinations of organizational antecedents. Originality/value It is the first attempt in post-Soviet Kazakhstan to systematically analyze the effect of knowledge governance on affective commitment. In addition, this paper offers a conceptual framework where affective commitment plays the mediating role in successful knowledge sharing.
Farnesoid X Receptor as Target for Therapies to Treat Cholestasis-Induced Liver Injury

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Recent studies on liver disease burden worldwide estimated that cirrhosis is the 11th most common cause of death globally, and there is a great need for new therapies to limit the progression of liver injuries in the early stages. Cholestasis is caused by accumulation of hydrophobic bile acids (BA) in the liver due to dysfunctional BA efflux or bile flow into the gall bladder. Therefore, strategies to increase detoxification of hydrophobic BA and downregulate genes involved in BA production are largely investigated. Farnesoid X receptor (FXR) has a central role in BA homeostasis and recent publications revealed that changes in autophagy due to BA-induced reactive oxygen species and increased anti-oxidant response via nuclear factor E2-related factor 2 (NRF2), result in dysregulation of FXR signaling. Several mechanistic studies have identified new dysfunctions of the cholestatic liver at cellular and molecular level, opening new venues for developing more performant therapies.
EP.WE.135Analysis of National Bariatric Surgery Related Clinical Incidents

Field: Health Professions (Health Sciences)

Abstract Background Hundreds of thousands of patient-safety clinical incidents are reported to the National Reporting and Learning System (NRLS) database in the United Kingdom (UK) every year. The purpose of this study was to identify bariatric surgery-related learning points from these incidents. Methods We analysed bariatric surgery-related clinical incidents reported to the UK NRLS database between 01 April 2005 and 31st October 2020. Results We identified 541 bariatric surgery-related clinical incidents in 58 different themes. Preoperative incidents represented 30.31% (N = 164), intraoperative 38.09% (N = 206), and postoperative accounted for 31.61% (N = 171). In terms of severity of incidents, (150;27.7%) were of high severity, whereas medium and low severity incidents were (244;45.1%) and (147;27.2%) respectively. The most common high severity theme was failure of thromboprophylaxis (50;9.2%). Intraoperative high severity incidents included 17 incidents of stapling of orogastric/nasogastric tubes or temperature probes, 8 missed needles, 8 broken graspers, and 6 incidents of band parts left behind. Postoperatively, the most common high severity theme was improper management of diabetes mellitus (DM) (35;6.5%). Medications errors represented a significant proportion of the medium severity incidents and included (26;4.8%) incidents of improper or missed prescription of routine medications and anticoagulants preoperatively and (45;8.3%) wrong prescriptions, dosage or prescribing of contraindicated medications postoperatively. Among the low severity themes identified there were (23;4.3%) incidents of postoperative diet problems, and (19;3.5%) patients listed for wrong procedures. Conclusion We identified 58 specific themes of bariatric surgery-related clinical incidents. Awareness of these themes should help to improve the safety of bariatric surgery worldwide.