jimnoneill/paper-to-field-training huggingface dataset:
Management of an invasive and metastatic Sertoli cell tumor with associated myelotoxicosis in a dog.

Field: Veterinary (Health Sciences)

We describe the surgical and post-operative management of a large, invasive, and metastatic functional Sertoli cell tumor in a 9-year-old cryptorchid male Labrador retriever dog. Despite residual disease after surgery, bone marrow recovery occurred without administration of bone marrow stimulants and serum estradiol accurately predicted tumor recurrence.
Delayed Hypersensitivity in vitro. III. Effect of Cortisone on Cytotoxicity of Mumps Viral Antigen.

Field: Immunology and Microbiology (Life Sciences)

Experimental mumps virus infections in guinea pigs are characterized in vivo by a positive delayed hypersensitive skin test reaction to viral antigen and in vitro by a cytotoxic effect of mumps virus antigen on cells from tissues cultivated from mumps-infected animals. Cortisone protects against this in vitro cytotoxicity of mumps virus.
Human T-lymphocyte-derived megakaryocyte colony-stimulating activity.

Field: Medicine (Health Sciences)

Conditioned medium from a T-lymphoblastic cell line (Mo) contains a number of well-characterized hemopoietins. In this paper we demonstrate that Mo cells also release a factor(s) able to stimulate the growth and the differentiation of megakaryocytic progenitors into large-size pure megakaryocytic colonies in plasma clot cultures. Comparison with other sources of human-active hemopoietins shows that Mo-conditioned medium performs better than others, especially for the megakaryocytic lineage. The factor(s) shows strong similarities with human Meg-CSF obtained from a thrombocytopenic patient's plasma, and is distinguishable from the other hemopoietins present in the medium.
Student's t-Generative Adversarial Networks

Field: Computer Science (Physical Sciences)

Generative Adversarial Networks (GANs) have a great performance in image generation, but they need a large scale of data to train the entire framework, and often result in nonsensical results. We propose a new method referring to conditional GAN, which equipments the latent noise with mixture of Student's t-distribution with attention mechanism in addition to class information. Student's t-distribution has long tails that can provide more diversity to the latent noise. Meanwhile, the discriminator in our model implements two tasks simultaneously, judging whether the images come from the true data distribution, and identifying the class of each generated images. The parameters of the mixture model can be learned along with those of GANs. Moreover, we mathematically prove that any multivariate Student's t-distribution can be obtained by a linear transformation of a normal multivariate Student's t-distribution. Experiments comparing the proposed method with typical GAN, DeliGAN and DCGAN indicate that, our method has a great performance on generating diverse and legible objects with limited data.
Effect of patch size and haziness factor on visibility using DCP

Field: Computer Science (Physical Sciences)

Outdoor images get corrupted due to fog and mist. Many techniques have been adopted to obtain to solve this problem but no such optimum solution is reached since each image has its own unique features. Dark channel prior method gives a significant idea about the amount of airlight responsible for the formation of haze. Dark channel with contrast controller and sky masking improves the visibility and also makes the method time efficient. But this method suffers from some artifacts. Here in this paper a novel technique has been introduced which can remove all the artifacts present in all the previous methods and also increases the visibility to such a level that even minute details in the haze free image can be easily viewed.
Supplementary Materials of Petrological confirmation of lithosphere thermally eroded by asthenospheric flow beneath the NE Tibetan plateau.docx

Field: Earth and Planetary Sciences (Physical Sciences)

Figure S1 Nb/Ta versus Nb of the West Qinling melilitites Figure S2 Os versus MgO and Ni contents of the West Qinling melilitites Figure S3 Observed versus predicted cpx components (CaTs, EnFs, DiHd) indicating the cpx crystals used for P–T estimate are in equilibrium with the host rocks. Table S1 Major and trace element data of the West Qinling melilitite samples Table S2 Re–Os isotopic compositions of the West Qinling melilitite samples Table S3 Sr–Nd–Pb isotopic compositions of the West Qinling melilitite samples Table S4 Microprobe data of clinopyroxene xenocryst in melilitite and clinopyroxene in xenoliths Table S5 Compiled microprobe data of clinopyroxene and their host rock compositions in the West Qinling Data source of experimental melts used in Figures 5 and 8 Pressure–depth conversion References (can be also seen in Supporting Information References)
Preparation of Cross-linked Sodium Alginate Microcapsules and Application in Releasing Drag

Field: Chemical Engineering (Physical Sciences)

Polymeric sodium alginate microparticles were prepared by cross-linking sodium alginate with glutaraldehyde.The extent of cross-linking was controlled by the time of exposure to glutaraldehyde.The sizes of the microcapsules with a diameter of 180-230μm were detected by Scanning Electron Microscopy(SEM).The release ratio of the Captopril from the microcapsules into an ethanol solution was monitored by High Performance Liquid Chromatography(HPLC).Experiment showed that the Captopril from the microcapsules released slowly in ethanol solution in 24 hour.
The psychological factors associated with poor compliance with treatment in asthma

Field: Psychology (Social Sciences)

Poor patient compliance with inhaled medication is known to cause morbidity and mortality in asthma. The reasons for nonadherence are not fully understood. We wondered whether psychological factors, such as patient attitudes to asthma and its treatment, anxiety, depression, and interpersonal problems, may be related to asthma self-care and compliance. In a prospective study, 102 patients with asthma, aged 18-70 yrs, requiring treatment with regular inhaled corticosteroids and beta-agonists were recruited from a hospital out-patient clinic and four general practices in South East London. They underwent psychological assessment using the Hospital Anxiety and Depression Scale (HADS), the Inventory of Interpersonal Problems (IIP), and a semi-structured interview focusing on patient attitudes, self-care, compliance, social support and treatment beliefs. Patients were given terbutaline and budesonide turbohalers to use twice daily over 12 weeks. Turbohaler Inhalation Computers (TICs) recorded each inhalation, providing a measurement of compliance. Seventy two patients completed the study. Thirty seven took less than 70% of the prescribed dose over the study period or omitted doses for 1 week and were defined as noncompliant. The noncompliant group had a higher mean (SD) score for depression (4.7 (3.3)) than the compliant group (3.2 (2.5)). The sample had a high mean (SD) score for anxiety (8.3 (4.4)), but there was no significant difference between the compliant and noncompliant groups. Patients' self-report and clinicians' impressions of compliance were not good predictors of actual compliance. Using discriminant analysis, a model was obtained from the questionnaires and interview items, which correctly classified 74% of the patients as compliant or non-compliant.(ABSTRACT TRUNCATED AT 250 WORDS)
Supporting diverse logistics analysis through WSMIS

Field: Decision Sciences (Social Sciences)

The Weapon System Management Information System (WSMIS) is described as satisfying a primary logistics management objective-to assess the status of weapon systems against meaningful mission-related operational criteria. To accomplish this, WSMIS assesses each weapon system's readiness and sustainability; identifies those items and resources which limit the weapon system's achievement of specified readiness and sustainability objectives; and develops and monitors get-well plans to reduce the negative effect that these items and resources have on a weapon system's combat capability. The broad range of WSMIS logistics analysis capabilities, the user community and their particular logistics analysis requirements, the WSMIS development philosophy, the information generation tools and procedures, and planned enhancements are outlined.< >
Electrochemical Biosensors for Pathogenic Bacteria

Field: Chemistry (Physical Sciences)

ABSTRACT OF THE DISSERTATIONElectrochemical Biosensors for Pathogenic BacteriabyNuvia Maria SaucedoDoctor of Philosophy, Graduate Program in ChemistryUniversity of California, Riverside, August 2015Professor Ashok Mulchandani, ChairpersonMicrobial diseases due to infections from bacteria and viruses constitute a major cause of death. Though recent technological advances have allowed for sensitive and selective detection of pathogenic bacteria, these methods are multi-step, have long assay times and require skilled lab technicians. Owing to the lack of point-of-care detection methods, clinical infections are often misdiagnosed as they rely on patient symptoms instead of empirical tests. This leads to prescription of inappropriate medication and prolonged suffering from infection. The use of antibiotics for viral infections and prescribing of ineffective antibiotics for bacterial infections has contributed to the rise of a new threat, the emergence of antibiotic-resistant bacteria. Thus, there is an urgent need for development of detection platforms which are sensitive, selective, point-of-care and allow for determination of the pathogen. To address this need, electrochemical biosensors were fabricated utilizing different transduction materials, including carbon nanotubes (CNTs), conductive polymer 4-(3-pyrrolyl) butyric acid, graphene and reduced graphene oxide (rGO). Owing to their high sensitivity, robustness, and ease of device integration, these materials are ideal candidates for the development of next generation biosensors. For selective capture of bacteria, the transducer surface was functionalized with lectins which serve as the bioreceptor element. The lectin-carbohydrate interactions, which are known to be highly specific, were exploited to result in unique binding profiles allowing for the distinction between bacterial and viral pathogens as well as between different bacterial strains. Further, the biosensors were capable of probing the viability of bacteria by detecting changes in pH caused by the excretion of metabolites from healthy bacterial cells. The proposed detection scheme thus allowed for screening of antibiotics and ranking of antibiotic efficacy against different bacterial strains. This work demonstrates the performance of these biosensors as quick screens for distinguishing bacterial from viral infections, a novel concept, and determining antibiotic efficacy prior to prescription thus addressing antibiotic misuse and the emergence of antibiotic resistant-bacteria.
PROCALCITONIN VS C-REACTIVE PROTEIN: COMPARISON AS MARKERS OF SEVERITY IN SEPSIS- A HOSPITAL BASED OBSERVATIONAL STUDY FROM NORTH EAST INDIA.

Field: Medicine (Health Sciences)

BACKGROUND: Sepsis is a life-threatening organ dysfunction caused by the dysregulation of a host's response to infections (1) which is further complicated by an altered metabolic state.Both CRP and Procalcitonin are accepted sepsis markers. But there is still some debate regarding the correlation between their serum concentrations and sepsis severity. MATERIALS AND METHODS A prospective observational study was carried out in patients >18 years with sepsis and meeting the inclusion and exclusion criteria for a period of 6 months from 1st September 2021 to 28th February,2022.The severity of sepsis related organ dysfunction was assessed by the SOFA score on day 1.Patients were categorized into 4 groups according to SOFA score as group 1 (0-6),group 2 (7-12),group 3 (13-18) and group 4(19-24). Serum PCT and CRP concentrations were measured on day 1 RESULTS A total of 50 patients presenting with sepsis were studied. The mean serum PCT concentration(ng/ml) in 4 SOFA groups was 7.61,28.47,40.16,85.09(p value<0.001) respectively. The mean CRP concentration (mg/ml) in 4 SOFA groups was 157.63,152.85,144.24,64.66 respectively (p value 0.13). Mean SOFA score was higher among patients who died (11.33±5.66) than those who survived (6.71±3.57) and the difference is statistically significant(p<0.001).The mean PCT (ng/ml) and CRP (mg/l) concentration in those who survived were 17.88 and 149.30 respectively and in those who died were 35.28(p value<0.001) and 160.46 (p value 0.167) respectively. The linear correlation between PCT plasma concentrations and the four categories was much stronger than in the case of CRP (Spearman's Rho,0.483 vs -0.197;p<0.001) CONCLUSION SOFA score and serum PCT concentration show significant correlation with respect to severity of organ dysfunction and outcome in sepsis patients compared to serum CRP concentration
Prognosis after Aortic Valve Replacement with Mechanical Valves and Bioprostheses: Use of Meta-analysis and Microsimulation

Field: Medicine (Health Sciences)

Aortic valve replacement (AVR) is a surgical procedure aimed at replacing a diseased aortic \nvalve with a prosthetic device. The prognosis of a patient after AVR depends on many interrelated factors. The objective of this thesis was to further develop and utilize the \nmicrosimulation methodology to determine the prognosis of patients after AVR with \nmechanical valves and bioprostheses, which in turn could assist in the optimal choice of a \nvalve prosthesis for a given patient.
Programming effects of antenatal dexamethasone in the developing mesolimbic pathways

Field: Neuroscience (Life Sciences)

Elevated glucocorticoids, during pregnancy, alter emotionality and increase propensity to drug abuse later in life, albeit through substrates and mechanisms are largely unknown. In this study, we examined whether antenatal glucocorticoid exposure induces enduring structural changes in the nucleus accumbens (NAcc), an important relay point in the reward limbic circuitry. To this end, rat dams were exposed to the synthetic glucocorticoid dexamethasone (DEX) on days 18 and 19 of gestation, and stereological tools were used to assess the total volume of, and neuronal numbers in, the NAcc, as well as the density of mesencephalic dopaminergic inputs from the ventral tegmental area (VTA) to the NAcc in their adult offspring. Further, we used measures of bromodeoxyuridine incorporation into NAcc cells to examine whether DEX-induced effects on cell proliferation represent another mechanism through which glucocorticoids alter the structure of mesolimbic pathways and might influence addictive behavior. Our studies show that exposure to DEX during late gestation results in significantly reduced volumes and cell numbers in the NAcc. The latter measure correlated strongly with a reduced rate of cell proliferation in DEX-exposed animals. Moreover, the treatment resulted in a decreased number of cells expressing tyrosine hydroxylase in the VTA and an impoverished dopaminergic innervation of the NAcc. These observations, which identify glucocorticoid-sensitive structures and neurochemical targets within the developing "reward pathway," pave way for future studies designed to understand how early life events can predispose individuals for developing drug dependence in adolescent and adult life.
Factors Associated with HIV Positive Serostatus Disclosure to Sexual Partners Among Sexually Active Young People on Anti-Retroviral Therapy in Central Uganda

Field: Medicine (Health Sciences)

David Kavuma,1– 3 Venantius Bbaale Kirwana,4,5 Mary Taani6 1Mildmay Institute of Health Sciences, Kampala, Uganda; 2School of Graduate Studies, Uganda Martyrs University-Nkozi, Kampala, Uganda; 3Makerere University School of Public Health, Kampala, Uganda; 4Monitoring, Evaluation and Learning, Sexual Reproductive Health and Rights Alliance, Kampala, Uganda; 5Makerere University School of Statistics and Applied Economics, Kampala, Uganda; 6Community Systems Strengthening, Mubende Region, Mildmay Uganda, Kampala, UgandaCorrespondence: David Kavuma, Tel +256772839416, Email davikavu@gmail.com; Venantius Bbaale Kirwana, Tel +256781630721, Email venbbak@gmail.comIntroduction: HIV serostatus disclosure is a fundamental HIV prevention and care strategy yet with a paucity of literature. This study comprehended the factors associated with HIV serostatus disclosure to sexual partners among young people aged 15– 24 years on anti-retroviral therapy (ART).Methods: This explanatory sequential study utilized quantitative data from 238 young people who had been on ART for over 12 months and were sexually active for at least 6 months in seven districts of Central Uganda. Pearson’s Chi-square and multinomial logistic regression analysis at α=0.05 was used to determine the factors associated with serostatus disclosure among study participants. Qualitative data from 18 young people were collected using an in-depth interview guide and analyzed thematically.Results: Non-disclosure was at 26.9%, one-way disclosure was at 24.4%, and two-way disclosure was at 48.7%. Participants who contracted HIV from their partners were three times more likely (RRR=2.752; 95% CI: 1.100– 6.888) to have one-way disclosure than non-disclosure, compared to those who had a perinatal infection. Those who contracted HIV from their partners were twice more likely (RRR=2.357; 95% CI: 1.065– 5.214) to have two-way disclosure than non-disclosure, compared to those who had a perinatal infection. Participants who stayed with their partners were four times more likely (RRR=3.869; 95% CI: 1.146– 13.060) to have two-way disclosure than non-disclosure, compared to those who stayed with their parents. Young people disclosed because they were tired of secrecy and desired treatment adherence and did not disclose due to fear of stigma and losing their partners’ support.Conclusion: Many sexually active young people on ART did not disclose their HIV-positive status to sexual partners mainly due to poverty, having multiple-sexual partners, and stigma. Interventions fighting stigma, multiple-sexual relationships, and poverty among sexually active young people on ART should be strengthened.Keywords: self-disclosure, one-way disclosure, two-way disclosure, non-disclosure, stigma, ART, single-sexual partner, multiple-sexual partners
Predicting reaction based on customer's transaction using machine learning approaches

Field: Computer Science (Physical Sciences)

<p><span lang="EN-US">Banking advertisements are important because they help target specific customers on subscribing to their packages or other deals by giving their current customers more fixed-term deposit offers. This is done through promotional advertisements on the Internet or media pages, and this task is the responsibility of the shopping department. In order to build a relationship with them, offer them the best deals, and be appropriate for the client with the company's assurance to recover these deposits, many banks or telecommunications firms store the data of their customers. The Portuguese bank increases its sales by establishing a relationship with its customers. This study proposes creating a prediction model using machine learning algorithms, to see how the customer reacts to subscribe to those fixed-term deposits or offers made with the aid of their past record. This classification is binary, i.e., the prediction of whether or not a customer will embrace these offers. Four classifiers that include k-nearest neighbor (k-NN) algorithm, decision tree, naive Bayes, and support vector machines (SVM) were used, and the best result was obtained from the classifier decision tree with an accuracy of 91% and the other classifier SVM with an accuracy of 89%.</span></p>
Mago (2), youngest brother of Hannibal

Field: Arts and Humanities (Social Sciences)

Mago was the youngest brother of *Hannibal, under whom he served in Italy (218–216 bce), fighting at the *Trebia and *Cannae. He fought in Spain from 215, playing an important part in the events that led to the death in 211 of Cn. *Cornelius Scipio Calvus and P. *Cornelius Scipio(1), until his defeat by P. *Cornelius Scipio Africanus at Ilipa, north of Seville (206; see Punic Wars). After failing to seize *Carthago Nova and to re-enter *Gades, he attacked the Balearic isles (*Baleares insulae; Mahon in Minorca perpetuates his name) and in 205 crossed to *Genua. After lengthy recruiting he advanced to the Po valley, where he was defeated by the Romans and severely wounded (203). Soon afterwards he, with Hannibal, was ordered to return to Africa to face Scipio; he died of wounds on the voyage.
A Service-Oriented Architecture framework for the distributed concurrent and collaborative design

Field: Computer Science (Physical Sciences)

The independent development capabilities of the new products reflect the core competitiveness of enterprises. The concurrent and collaborative design for complex product is a new mode of design based on concurrent engineering and multidisciplinary collaborative design, using various fields of CAX/DFx. At present, the most advanced collaborative work technology is based on the Service-Oriented Architecture (SOA). According to the theory of concurrent engineering and the optimization theory in the multidisciplinary collaborative design, the paper defines the concept of DCCD-distributed concurrent and collaborative design. Based on SOA and the distributed services environment, this paper first presents a novel distributed concurrent and collaborative design platform architecture. The architecture integrates some Large-scale commercial engineering softwares (such as Pro/E, HaperMesh and ANSYS) to quickly accomplish the design and analysis of complex product. Using the java programming language, this paper defines the interface description of the services and gives detailed introductions to the architecture by a demonstration of railway bogie. Compared with the traditional collaborative design platform, this architecture can shorten the cycle of service exchange, and strongly support concurrent and collaborative design for the complex product.
The cauldron at the core of SS 433

Field: Physics and Astronomy (Physical Sciences)

We propose that the jets in SS 433 are accelerated just outside the magnetopause of a magnetized neutron star. Although the escape speed from this radius is subrelativistic, the jets are able to attain a nearly relativistic speed by passing through narrow de Laval nozzles, which are stabilized from below by the tension in the magnetic field. The narrowness of the nozzles accounts ultimately for the collimation of the jets. No funnel or vortex is necessary, and the gas outside the magnetopause need not be rapidly rotating. In order to be accelerated by electron scattering radiation pressure, the jets must carry a highly supercritical energy flux, L > 1039 erg s−1. This energy may be supplied by one of two processes: (1) a highly inhomogeneous shower of ‘broomsticks’ or blobs on to the surface of the neutron star; or (2) the rapid spin of the neutron star, which causes the oblique magnetosphere to drive shocks into the surrounding gas. In either case, the magnetopause defines the extent of a ‘cauldron’ within which radiant energy is violently mixed with gas settling in from outside. The weight of the slowly accreting gas determines the size of the magnetosphere. From the observed collimation and velocity of the SS 433 jets we infer the properties of the confining cloud and constrain the parameters of the energy source. We argue that the velocity of the jets should be insensitive to fluctuations in the accretion rate, in agreement with observations. The photosphere of the cloud should be a strong source of far-ultraviolet continuum, which cannot be observed directly but which may be responsible for exciting the strong ‘stationary’ emission lines.