jimnoneill/paper-to-field-training huggingface dataset:
Proton pump (H+/ K+-ATPase) expression in human larynx

Field: Medicine (Health Sciences)

Laringofaringealni refluks je trenutno nedovoljno istražena bolest, a smatra se da je djelomicno odgovoran za nastanak bolesti grkljana. Nastaje povratom kiseloga sadržaja iz želuca, ali postoje naznake o grkljanu kao mjestu stvaranja kiseline, uslijed djelovanja protonske pumpe u sluznici. U radu je prisutnost protonske pumpe u sluznici grkljana utvrđivana imunohistokemijskim dokazivanjem na uzorku od 50 kadavera i 11 živih pacijenata kod kojih je ucinjena laringektomija. Za sve pacijente uzorci tkiva su obrađeni, te je istraživanje provedeno u Imunohistokemijskom laboratoriju Medicinskog fakulteta Sveucilista Josipa Jurja Strossmayera u Osijeku. Dokazana je prisutnost protonske pumpe u seromukoznim žlijezdama grkljana u podrucju supraglotisa. Po prvi je put u literaturi utvrđena prisutnost protonske pumpe u ljudskim hondrocitima stitne i epigloticne hrskavice. Zakljucak: Dokazana ekspresija protonske pumpe ostavlja prostor za dodatna istraživanja laringofaringealnog refluksa, ali i patofiziologije hrskavicnih poremecaja.
Pricing Decision Models for Remanufactured Short-Life Cycle Technology Products with Generation Consideration

Field: Decision Sciences (Social Sciences)

Although the analysis of remanufactured durable products dominates the environmentally conscious manufacturing research, more and more researchers try to focus on modelling short-life cycle products remanufacturing decisions. High-technology products, such as smartphones and laptops are the cases in point. Smartphone companies are opening remanufacturing facilities in third world countries to attract middle-level customers. Remanufacturing of high technology short life products can have a positive impact on the profits as well as the environment. A common strategy for the technology-intensive companies is to update their products continuously to maintain market share as well as customers' appetites for latest technologies. This creates a multiple-generational product line. When a new generation is released, the market value of the previous generation is reduced, and the price of the generation before last is decreased even more. Meanwhile, remanufactured products of each generation also come to market when they are available. This can result in complex cannibalization among various generational product lines as well as new and remanufactured products. In this study, we develop a model that addresses the issue of pricing the latest generation remanufactured products and old generation new products. The demands are time-dependent and price sensitive. The market is separated from that of the brand new product of latest generation. The system consists of a retailer and a manufacturer. Two scenarios are evaluated in the system. First, each party tries to optimize profit independently. Second, the joint profit is optimized. The results provide optimal pricing decisions in different selling periods.
A heuristic algorithm to schedule twin yard crane to Mmnimize job tardiness in container terminals

Field: Decision Sciences (Social Sciences)

With global trading business in the South East Asian region as well as the Greater Asian region growing rapidly, Singapore is well positioned to benefit from this upward trend of sea trade. Without expanding its resources to its maximum capacity in the various container terminals located throughout the country, Singapore will fall behind its competitors as the maximum workload increases yearly. In order to prevent such a scenario from happening, steps must be done to improve the container terminal efficiency to cope with workload for the foreseeable future. This project aims to help container terminal minimize the vessel turnaround time. By adapting the greedy heuristics onto a double yard crane single rail mounted gantry system, we hope to explore if this rule can be extended to this setup accounting for job tardiness with two yard cranes. From this project, it shows that the combination of the ATCRSS and greedy algorithm can be applied on a double yard crane single rail mounted gantry with an additional factor which includes the safety distance between the service crane as well as the physical limitations of the yard crane setup.
Adsorbent activity of pectin and activated charcoal from pineapple peel waste as biosorbent against heavy metals and dyes

Field: Environmental Science (Physical Sciences)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Nerdy Nerdy, Linta Meliala, Jon Piter Sinaga, Selamat Ginting, Effendy De Lux Putra, Tedy Kurniawan Bakri; Adsorbent activity of pectin and activated charcoal from pineapple peel waste as biosorbent against heavy metals and dyes. AIP Conference Proceedings 30 January 2023; 2613 (1): 040003. https://doi.org/10.1063/5.0120262 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Effect of Temperature and Light Intensity on Growth of the Regenerated Bulblet of Fritillaria camtschatcensis Ker-Gawl. in Vitro Culture.

Field: Agricultural and Biological Sciences (Life Sciences)

本実験はクロユリ (Fritillaria camtschatcensis KerGawl.) の小球状りん片由来の再生子球を供試し, in vitro培養での子球重, 出葉および発根に及ぼす温度と照度の影響を検討した.その結果, 子球重の増加と出葉促進には培養温度20℃, 発根促進には20～25℃が良好であった.子球重の増加に照度効果はないものの, 出葉促進は150～300μmol m-2s-1, 発根促進には300μmol m-2s-1が効果的であった.いっぽう, 出葉は暗黒下でまったく認められなかった.
Spin Polarization in a Curvature-controlled Quantum Point Contact

Field: Physics and Astronomy (Physical Sciences)

The conductance of the quantum point contact (QPC) has a shoulder‐like anomaly below the last conductance plateau, which is called "0.7 anomaly." By using a single QPC, we succeed in controlling the presence of the anomaly by tuning the potential for defining the QPC. We also performed the noise measurement when the QPC has the 0.7 anomaly to find that the Fano factor is smaller than the theory based on the free‐electron model. This would be explained by assuming the spin polarization in the last conducting channel.
Scope of Right to Information Act in Enabling Local Development in Nepal

Field: Social Sciences (Social Sciences)

This paper aims to explore the impact and potential of the Right to Information (RTI) Act in advancing local development initiatives in Nepal. Historically, local development governance faced challenges, including limited awareness among stakeholders, delays in service delivery, and issues related to corruption, transparency, and accountability. Enacted in 2007, the RTI Act represents a groundbreaking legislative step, obligating public authorities to actively disclose and disseminate information to support local development efforts. This law empowers citizens to engage more effectively with local authorities, fostering responsive and community-oriented development. The study employs qualitative methods with an exploratory and descriptive approach, using purposively selected case studies from Kathmandu Metropolitan City and Sunkoshi Rural Municipality in Okhaldhunga. The findings highlight that transparency and accountability within local government administration are essential for participatory democracy. Overall, the RTI Act is shown to be a transformative tool for citizens, significantly enhancing governance by supporting transparency, accountability, citizen involvement, and effective local development governance.
Control of Blood Pressure: Does It Matter Which Agent You Use?

Field: Medicine (Health Sciences)

A panel was convened to discuss the question, “Is blood pressure lowering the sole determinant of outcome, or do specific drugs make a difference?” The panel was moderated by Marvin Moser, MD, Clinical Professor of Medicine at the Yale University School of Medicine, New Haven, CT. Panelists included Norman Kaplan, MD, Clinical Professor of Medicine at the University of Texas Southwestern Medical Center at Dallas, TX, and William Cushman, MD, Professor of Medicine at the University of Tennessee in Memphis, TN. The discussion was supported by Boehringer Ingelheim, and each author received an honorarium from Boehringer Ingelheim for time and effort spent participating in the discussion or reviewing the transcript for intellectual content before publication. The authors maintained full control of the discussion and the resulting content of this article.
The effect of inhaled glucocorticoid on the content of Na+/K+-pumps in human skeletal muscles

Field: Medicine (Health Sciences)

Introduction: Inhaled glucocorticoids are commonly used in treatment of asthma. Systemically administered glucocorticoids increase Na+/K+-pump content of skeletal muscles and enhances exercise capacity in humans. Systemic use of glucocorticoids is as such restricted by anti-doping authorities. However, the effect of inhaled glucocorticoids on Na+/K+-pump content of skeletal muscles is unexplored in humans. We examined the effect of two-week therapeutic inhalation of [Spirocort] (4x400 µg/d) on muscle Na+/K+-pump content and exercise capacity in healthy men. Methods: Ten men (24±5 yrs, 50±6 ml/kg/min; means±SD) participated in the study. Before and after the intervention, subjects had biopsies taken from m.vastus lateralis, after which they inhaled 4 mg [Bricanyl] to stimulate the Na+/K+-pumps. Thirty min after inhalation, subjects exercised to fatigue at an intensity of 90% of incremental peak power output (iPPO). Muscle biopsies were analyzed for Na+/K+-pump content by [3H]ouabain binding. Results: After the intervention, muscle Na+/K+-pump content was higher (P<0.01) compared with before (297±36 to 343±37 pmol/g)(fig. 1). No difference was observed in time to fatigue at 90% of iPPO (203±89 to 206±117 s). Conclusion: Two-week inhalation of glucocorticoid increases the content of Na+/K+-pumps without augmenting iPPO in human skeletal muscles. This finding is relevant for asthma patients and anti-doping authorities.
Insulin Resistance: A Multifaceted Syndrome Responsible for NIDDM, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular Disease

Field: Medicine (Health Sciences)

Diabetes mellitus is commonly associated with systolic/diastolic hypertension, and a wealth of epidemiological data suggest that this association is independent of age and obesity. Much evidence indicates that the link between diabetes and essential hypertension is hyperinsulinemia. Thus, when hypertensive patients, whether obese or of normal body weight, are compared with age- and weight-matched normotensive control subjects, a heightened plasma insulin response to a glucose challenge is consistently found. A state of cellular resistance to insulin action subtends the observed hyperinsulinism. With the insulin/glucose-clamp technique, in combination with tracer glucose infusion and indirect calorimetry, it has been demonstrated that the insulin resistance of essential hypertension is located in peripheral tissues (muscle), is limited to nonoxidative pathways of glucose disposal (glycogen synthesis), and correlates directly with the severity of hypertension. The reasons for the association of insulin resistance and essential hypertension can be sought in at least four general types of mechanisms: Na+ retention, sympathetic nervous system overactivity, disturbed membrane ion transport, and proliferation of vascular smooth muscle cells. Physiological maneuvers, such as calorie restriction (in the overweight patient) and regular physical exercise, can improve tissue sensitivity to insulin; evidence indicates that these maneuvers can also lower blood pressure in both normotensive and hypertensive individuals. Insulin resistance and hyperinsulinemia are also associated with an atherogenic plasma lipid profile. Elevated plasma insulin concentrations enhance very-low-density lipoprotein (VLDL) synthesis, leading to hypertriglyceridemia. Progressive elimination of lipid and apolipoproteins from the VLDL particle leads to an increased formation of intermediate-density and low-density lipoproteins, both of which are atherogenic. Last, insulin, independent of its effects on blood pressure and plasma lipids, is known to be atherogenic. The hormone enhances cholesterol transport into arteriolar smooth muscle cells and increases endogenous lipid synthesis by these cells. Insulin also stimulates the proliferation of arteriolar smooth muscle cells, augments collagen synthesis in the vascular wall, increases the formation of and decreases the regression of lipid plaques, and stimulates the production of various growth factors. In summary, insulin resistance appears to be a syndrome that is associated with a clustering of metabolic disorders, including non-insulin-dependent diabetes mellitus, obesity, hypertension, lipid abnormalities, and atherosclerotic cardiovascular disease.
Correlating Stiffness, Ductility, and Morphology of Polymer:Fullerene Films for Solar Cell Applications

Field: Materials Science (Physical Sciences)

Abstract The development of flexible and physically robust organic solar cells requires detailed knowledge of the mechanical behavior of the heterogeneous material stack. However, in these devices there has been limited research on the mechanical properties of the active organic layer. Here, two critical mechanical properties, stiffness and ductility, of a widely studied organic solar cell active layer, a blend film composed of poly(3‐hexylthiophene) (P3HT) and [6,6]‐phenyl C61‐butyric acid methyl ester (PCBM) are reported. Processing conditions are varied to produce films with differing morphology and correlations are developed between the film morphology, mechanical properties and photovoltaic device performance. The morphology is characterized by fitting the absorption of the P3HT:PCBM films to a weakly interacting H‐aggregate model. The elastic modulus is determined using a buckling metrology approach and the crack onset strain is determined by observing the film under tensile strain using optical microscopy. Both the elastic modulus and crack onset strain are found to vary significantly with processing conditions. Processing methods that result in improved device performance are shown to decrease both the compliance and ductility of the film.
Effect of vegetable oils with different fatty acid composition on high-fat diet-induced obesity and colon inflammation

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Taken together, our data indicate that the three oils exert similar anti-obesity effects. Interestingly, compared with olive oil and SO, PO provides better protection against high-fat diet-induced colon inflammation, suggesting that PO consumption helps manage inflammation-related diseases and provides omega-3 fatty acids needed by the body.
The role of indirect connections in gene networks in predicting function

Field: Computer Science (Physical Sciences)

Abstract Motivation: Gene networks have been used widely in gene function prediction algorithms, many based on complex extensions of the ‘guilt by association’ principle. We sought to provide a unified explanation for the performance of gene function prediction algorithms in exploiting network structure and thereby simplify future analysis. Results: We use co-expression networks to show that most exploited network structure simply reconstructs the original correlation matrices from which the co-expression network was obtained. We show the same principle works in predicting gene function in protein interaction networks and that these methods perform comparably to much more sophisticated gene function prediction algorithms. Availability and implementation: Data and algorithm implementation are fully described and available at http://www.chibi.ubc.ca/extended. Programs are provided in Matlab m-code. Contact: paul@chibi.ubc.ca Supplementary information: Supplementary data are available at Bioinformatics online.
Signal Transduction by Receptors for BAFF and APRIL

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The cytokines B-cell-activating factor of the TNF family (BAFF) and A proliferation-inducing ligand (APRIL) stimulate several of the major signaling cascades responsible for B-cell homeostasis. Transmitting these stimuli to the intracellular milieu are the receptors B-cell maturation antigen (BCMA), transmembrane activator and CAML interactor (TACI), and BAFF receptor (BAFFR). While evidence for the activation of several nuclear-independent pathways is accumulating, the most consistent, reproducibly detectable molecular effect of stimulating cells with BAFF or APRIL is activation of the NF-κB family of transcription factors. Here, we will summarize the current state of knowledge about BAFF and APRIL signaling; from the membrane-proximal events that are distinct to BCMA, TACI, and BAFFR to the differences in the downstream pathway types and kinetics that are manifest in the phenotypic extremes of their respective knockout mouse models.
In Vitro Effect of Porcelain Firing Cycle and Different Thicknesses of IPS E.max CAD Core on Marginal Accuracy of All-Ceramic Restorations.

Field: Dentistry (Health Sciences)

The porcelain firing cycle increases marginal gap in IPS e.max CAD restorations; 0.3 mm decrease in core thickness slightly increased marginal discrepancy, however it was not significant.
Open Access: Governing Islam in French cities: defining ‘acceptable’ public religiosity through municipal consultative bodies

Field: Social Sciences (Social Sciences)

In recent years, European states have institutionalised relations with Islamic groups in the form of national Islam councils. Similarly, municipalities have set up more or less comparable bodies to address issues related to urban religious diversity. However, rather than being restricted to Muslim representatives, municipal consultative bodies usually incorporate a variety of religious actors. This contribution analyses three such bodies in the French cities of Rennes, Bordeaux, and Toulouse. Adopting a governance perspective and drawing on qualitative fieldwork, I argue that by providing concrete advice on how to address religious issues, these bodies define what are considered 'acceptable' and 'unacceptable' public religious expressions, ultimately influencing normative ideas about laïcité. Moreover, I argue that the history of relationships between religious and municipal authorities and the political culture of the cities, among other factors, shape these local processes, thereby emphasising the distinct role of cities and urban actors in governing religion.
The incidence of type 1 diabetes in Republic of Srpska (Bosnia and Herzegovina) and Slovenia in the period 1998-2010

Field: Medicine (Health Sciences)

The incidence for age group 0-18 yr standardized to the world population is remarkably higher in Slovenia than in the Republic of Srpska. Further follow-up and investigations are needed to explain the high difference in incidence of T1DM between the two geographically related countries.
Memory‐efficient compression of 𝒟ℋ2‐matrices for high‐frequency Helmholtz problems

Field: Mathematics (Physical Sciences)

Abstract Directional interpolation is a fast and efficient compression technique for high‐frequency Helmholtz boundary integral equations, but requires a very large amount of storage in its original form. Algebraic recompression can significantly reduce the storage requirements and speed up the solution process accordingly. During the recompression process, weight matrices are required to correctly measure the influence of different basis vectors on the final result, and for highly accurate approximations, these weight matrices require more storage than the final compressed matrix. We present a compression method for the weight matrices and demonstrate that it introduces only a controllable error to the overall approximation. Numerical experiments show that the new method leads to a significant reduction in storage requirements.
Ly-alpha Emitting Galaxies at z = 2.1: Stellar Masses, Dust and Star Formation Histories from Spectral Energy Distribution Fitting

Field: Physics and Astronomy (Physical Sciences)

We study the physical properties of 216 z ~ 2.1 LAEs discovered in an ultra-deep narrow-band MUSYC image of the ECDF-S. We fit their stacked Spectral Energy Distribution (SED) using Charlot & Bruzual templates. We consider star formation histories parametrized by the e-folding time parameter tau, allowing for exponentially decreasing (tau>0), exponentially increasing (tau<0), and constant star formation rates. These LAEs are characterized by best fit parameters and 68% confidence intervals of log(M_*/M_sun)=8.6[8.4-9.1], E(B-V)=0.22[0.00-0.31], tau=-0.02[(-4)-18] Gyr, and age_ SF=0.018[0.009-3] Gyr. Thus, we obtain robust measurements of low stellar mass and dust content, but we cannot place meaningful constraints on the age or star formation history of the LAEs. We also calculate the instantaneous SFR to be 35[0.003-170] M_sun/yr, with its average over the last 100 Myr before observation giving _100=4[2-30] M_sun/yr. When we compare the results for the same star formation history, LAEs at z~2.1 are dustier and show higher instantaneous SFRs than z~3.1 LAEs, while the observed stellar masses of the two samples seem consistent. LAEs appear to occupy the low-mass end of the distribution of star forming galaxies at z~2. We perform SED fitting on several sub-samples selected based on photometric properties and find that LAE sub-samples at z~2.1 exhibit heterogeneous properties. The IRAC-bright, UV-bright and red LAEs have the largest stellar mass and dust reddening. The UV-faint, IRAC-faint, and high equivalent width LAE sub-samples appear less massive (<10^9 M_sun) and less dusty, with E(B-V) consistent with zero.
Open Forum as an Active Learning Method for Teaching Lean Construction

Field: Business, Management and Accounting (Social Sciences)

While many construction companies claim substantial productivity and profit gains due to the utilization of lean construction principles, it is a challenge to teach these principles in a class room setting due to limited literature on pedagogy in lean construction. The Construction Management Department at Colorado State University embarked on a lean journey by incorporating lean into construction education. While class lecture is usually the main method used in course teaching, employing a combination of teaching methods in the classroom will accommodate different students’ learning styles, resulting in higher achievement and satisfaction. This paper reports an open forum teaching method where students interactively share ideas and actively learn from class discussions, case studies, and required readings. The success behind this pedagogical approach largely depends on student engagement and motivation. The research procedures used in this paper include ethnography, action research, and a survey. The class instructor/first author is running this experimental method, collecting data, analyzing the findings, and introducing improvements. The second author, who is auditing the class, provides insider insights on the teaching method, student morale, and class environment. In addition, the authors are administering a class survey at the beginning of instruction and the end of the course to evaluate this open forum teaching method. The purpose of employing the open forum method is to lay the foundation of a new pedagogy in teaching lean construction. Through this teaching method we hope to create a community of inquiry and learning among students. It is expected that this teaching method will facilitate a lean understanding among construction students while preparing them to enter the workforce with a solid theoretical understanding of lean and its transferability to construction processes. NOMENCLATURE Active learning, Lean education, Open class forum, Lean construction.