jimnoneill/paper-to-field-training huggingface dataset:
Passive Transfer of Antibodies to Human T-Cell Lymphotropic Virus Type III in Patients Receiving High-Dose Intravenous Immunoglobulin

Field: Medicine (Health Sciences)

To the Editor.—

Immune serum globulins derived from pooled plasma are being scrutinized as a possible source of viral infection and a cause of seroconversion to the viral antibodies.1,2Recently, there has been evidence that antibody to human T-cell lymphotropic virus type III (anti-HTLV-III) is present in anti-hepatitis B immunoglobulin and may inducea transient seroconversion.2Fortunately, there is no evidence that hepatitis B vaccines transmit HTLV-III infection or are associated with the development of the acquired immunodeficiency syndrome.2,3We recently evaluated several immunoglobulin preparations for the presence of anti-HTLV-III and studied whether hypogammaglobulinemic patients who had been receiving high-dose intravenous immunoglobulins developed positive serological test findings for anti-HTLV-III. Four of five immunoglobulin preparations were positive for anti-HTLV-III by enzyme immunoassay; however, only two preparations were positive by Western blot analysis (Table). Eleven patients with common variable hypogammaglobulinemia who had received intravenous immunoglobulin therapy for more than two years were studied. None of these
Music visualization-based game design and research

Field: Computer Science (Physical Sciences)

With reference to the creation of the independent game StarMusiX,this paper provided a new method of designing game scenes in order to solve such problems as high cost and low efficiency in development and production of game scenes.The method is that external data was analyzed in real-time and the result was recognized as the driving factors of real-time game scenes building,meanwhile the details of game scenes were generated by program.In the experimental game,scenes can be generated by inputting and analyzing music-data and a full expression can be found in music-visualization.This verifies the rationality and feasibility of the above methods.The experimental results indicate that the method effectively improves the efficiency of game scenes design.
Post-Cholecystectomy Gossypiboma Mimicking the Liver Hydatid Cyst

Field: Medicine (Health Sciences)

Gossypiboma is also called as retained foreign body or surgical sponge a rare and serious complication following the major surgical intervention. It is commonly occurred after major abdomino-pelvic surgery and can cause significant morbidity and mortality. We present a case of large gossypiboma within the liver parenchyma in post-operative patient radiologically mimicking the hydatid cyst and its surgical findings.
Anti-CD4 autoantibodies in immunological nonresponder people with HIV: cause of CD4+ T-cell depletion?

Field: Medicine (Health Sciences)

Objective: We aimed to evaluate the anti-CD4 IgG role in the poor immune recovery of immunological nonresponder people with HIV (INR). Design: INR display low CD4 + T-cell increase despite long-term undetectable viremia. Among other factors, autologous anti-CD4 IgG-dependent cellular cytotoxicity (ADCC) by natural killer (NK) cells has been proposed to cause CD4 + T-cell depletion. Methods: Plasma anti-CD4 IgG levels were quantified and purified by chromatography columns for the subsequent use in a coculture of CD4 + T and NK cells. We analyzed NK cell degranulation markers (CD107a, perforin and granzyme B) and IFN-γ release, and CD4 + T-cell death. Binding affinity of anti-CD4 IgG for CD4 + T cells was also assessed. Results: A total of 168 individuals were enrolled (INR, 56; immunological responders, 40; treatment-naive, 39; and healthy controls, 33). The highest anti-CD4 IgG levels were found in treatment-naive people with HIV (PWH), followed by participants on treatment. There were no correlations between anti-CD4 IgG levels and CD4 + T-cell counts. In a 15-participant subgroup (naive, immunological responders, and INR), anti-CD4 IgG induced a slight NK-cell expression of degranulation markers and IFN-γ; however, the percentage of CD4 + T-cell death was negligible. Consistently, no significant changes in NK cell polyfunctionality were observed. In addition, purified anti-CD4 IgG showed scarce binding affinity for CD4 + T cells. These results were similar in all analyzed participant groups. Conclusion: Our results suggest that autologous anti-CD4 IgG neither trigger CD4 + T-cell death by ADCC nor are responsible for CD4 + lymphocyte depletion in INR.
Outer forms of type $A_{2}$ with infinite genus

Field: Mathematics (Physical Sciences)

Let G be an absolutely almost simple algebraic group over a field K . The genus \mathbf{gen}_{K}(G) of G is the set of K -isomorphism classes of K -forms G' of G that have the same K -isomorphism classes of maximal K -tori as G . We construct an example of outer forms of type A_{2} with infinite genus. The submission date of this paper had been incorrectly displayed on the web page between 2 July 2024 and 5 June 2025. For the details, see the .
Volume correction in the aging hand: role of dermal fillers

Field: Medicine (Health Sciences)

Alexander Z Rivkin David Geffen/UCLA School of Medicine Los Angeles, CA, USA Abstract: The hands, just like the face, are highly visible parts of the body. They age at a similar rate and demonstrate comparable changes with time, sun damage, and smoking. Loss of volume in the hands exposes underlying tendons, veins, and bony prominences. Rejuvenation of the hands with dermal fillers is a procedure with high patient satisfaction and relatively low risk for complications. This study will review relevant anatomy, injection technique, clinical safety, and efficacy of dermal filler volumization of the aging hand. Keywords: dermal fillers, hands, volumization, hyaluronic acid, calcium hydroxylapatite
Non-Invasive Ventilation: The Impact of a Home Health Support

Field: Health Professions (Health Sciences)

Non-invasive ventilation seems to have gained in popularity in the past few years for pediatric patients with a variety of disease processes. Although it is infrequently used for acute respiratory failure, it is becoming a popular choice for ventilation assistance in a variety of chronic disease processes and not just limited to asthma, cystic fibrosis and other neurological disorders that impair breathing. As the medical team acquires more experience in non-invasive ventilation, a new frontier in the home setting is now being explored.
Direct observation of the Ni stabilising effect in interfacial (Cu,Ni)6Sn5 intermetallic compounds

Field: Materials Science (Physical Sciences)

The polymorphic transformation in interfacial intermetallic compounds in three lead-free solder joints was investigated using in situ heating/isothermal/cooling observation techniques in high-voltage transmission electron microscopy (HVTEM). Here, the hexagonal η- to monoclinic η′-Cu6Sn5 polymorphic transformation was visualised systematically through zone-axis electron diffraction patterns and real-space imaging. Cu6Sn5 grains obtained in the as-reflowed solder joints that did not contain Ni (Sn–0.7Cu/Cu and Sn–3.0Ag–0.5Cu/Cu) show weak reflections in the diffraction patterns from the η′-Cu6Sn5. In Sn–0.7Cu–0.05Ni/Cu joints, no weak reflections were present in the diffraction patterns of the (Cu,Ni)6Sn5 grains indicating the presence of Ni prevented the η- to η′-Cu6Sn5 transformation. The movement of bend contours was also observed at around 186 °C in adjacent the grain boundaries in Cu6Sn5 but not in the (Cu,Ni)6Sn5. We also uncover the origin of the weak reflections and confirm the superstructure of monoclinic η′-Cu6Sn5 by obtaining atomic-resolution images within the areas from which the selected area diffraction patterns were obtained.
Seductions of Place: Geographical Perspectives on Globalization and Touristed Landscapes

Field: Social Sciences (Social Sciences)

The seductiveness of touristed landscapes is simultaneously local and global, as travelled places are formed and reworked by the activities of diverse, mobile people, in their desires to experience situated, sensuous qualities of difference. Cartier and Lew’s interesting and informative book explores contemporary issues in travel and tourism and human geography, and the complex cultural, political, and economic activities at stake in touristed landscapes as a result of globalization.
This book assesses travel and tourism as simultaneously cultural and economic processes, through ideas about place seduction and the formation of landscapes. Throughout, examples are given from urban and environmental touristed landscapes, from major world cities to tropical islands, and chapter contributions include:

an analysis of the representational character of landscape and the built environment
historic constructions of place seduction
the importance of class, racial, and gender dimensions of place
how mobility and the seduction of place orient identity formation
the environmental impacts of tourism economies.
Broad in scope, this book is ideal for social scientists and humanists who are interested in contemporary debates about place studies, mobility, and the located realities of globalization.
The equivalent representation of pyramidal absorbers and its application to the analysis of electromagnetic wave absorber's characteristics

Field: Engineering (Physical Sciences)

The reflectivity of a pyramidal absorber is analyzed accurately by using the spatial network method. As a practical modeling of the pyramidal absorber, a novel modeling technique based on a synthesized capacitance model is proposed to analyze its reflectivity. The validity of the proposed model is confirmed through the comparison with results given by the accurate analysis for the normal incidence and through the comparison with experimental results. The proposed model can be applied to calculate the reflectivity of pyramidal absorber for the oblique incidence as well as for the normal incidence of electromagnetic wave.
Oscillation of Nonlinear Neutral Delay Differential Equations

Field: Mathematics (Physical Sciences)

In this paper,oscillation of nonlinear neutral delay differential equation[x(t)-px~a(t-π)]′+f(t,x(t-σ))=0,tt_0 is considered.A sufficient condition and a necessary condition are obtained which guarantee every bounded solutions of the above equation oscillates in the case when p,τ∈(0,∞),(σ∈),α≠1 and f(t,x) is continuous function of [t_0,+∞]×R.The results generalize main result of literature [5].
Abstract 3859: MicoRNAs in regulation of colon cancer stem cells

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Accumulating evidence supports the contention that epithelial cancers, including sporadic colorectal cancer (CRC), the incidence of which increases sharply after the age of 50 years, are diseases driven by self-renewing cancer stem/stem-like cells (CSCs). We have reported that CSC population in the colonic mucosa increases with advancing age. This was accompanied by a concomitant rise in microRNA-21 (miR-21) and reduction in miR-145 in the colonic mucosa. Interestingly, increased levels of miR-21 and reduction in miR-145 were noted in the colonic mucosa of patients with adenomatous polyps or CRC. These observations prompted us to speculate a role for miR-21 and miR-145 in regulating CSCs in the colonic mucosa. Indeed, we found that overexpression of miR-21 in colon cancer cells greatly increases CSCs and also induces tumor growth. An opposite phenomenon was noted in colon cancer cells where miR-145 was upregulated through stable transfection. In addition, studies utilizing SCID mice xenograft model of colon cancer showed that administration of either antagomir-21 (anti-sense miR-21) or excess miR-145 greatly inhibited the growth of tumors of colon cancer cells, when compared with the controls. This reduction in growth was associated with decreased expression of CD44, B-catenin and Sox-2 and induction of CK-20. In vitro cell culture studies have further demonstrated miR-21 to regulate miR-145 and vice versa. Although the precise mechanism(s) by which miR-21 or miR-145 regulates CSCs in the colonic mucosa during the progression of CRC is unknown, our in vitro studies suggest that they induce differentiation of colon CSCs. The latter was evidenced by the increased expression of CK-20 in colon cancer cells following downregulation of miR-21 and upregulation of 145. In contrast, Sox-2 expression is decreased following overexpression of miR-145. In conclusion, our current observations suggest that miR-21 and miR-145, that are upregulated and downregulated, respectively, in the colonic mucosa during aging and CRC, play critical roles in regulating CSCs in the colon. Citation Format: Yingjie Yu, Nangia-Makker Pratima, Sindhu Rajendra, Edi Levi, Adhip P. N. Majumdar. MicoRNAs in regulation of colon cancer stem cells. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 3859. doi:10.1158/1538-7445.AM2014-3859
Identifying technology convergence across FinTech: an integrated approach of text mining and association rule mining

Field: Computer Science (Physical Sciences)

Purpose Financial technology (FinTech) has significantly transformed and advanced the traditional financial services sector. The aim of this study is to identify the technology convergence (TC) and innovation trends utilizing both text and data mining techniques on patent data within the FinTech domain. Design/methodology/approach A total of 36,335 patents in FinTech were retrieved for analysis from the Lens database. Bidirectional Encoder Representations from Transformers topic modelling was performed on the Abstract and Claims Text Dataset. Association rule mining (ARM) was performed on 204 distinct Cooperative PClassification (CPC) codes among the retrieved patent data. The interestingness measures calculated were confidence, Kulczynski and imbalance ratio (IR). Findings Top five topics obtained revealed the convergence of Fintech into blockchain, advertising, information processing, logistics and geolocation-based payment. Findings also highlighted the organizations such as Bank of America, Capital One, IBM, Amazon and Mastercard being the key players in the topics obtained. ARM revealed 405 association rules across 31 distinct CPC codes, revealing convergence across data and image processing, along with machine learning, biometrics and a significant number of patents in energy management systems and renewable energy. Practical implications BERT topic modelling, combined with ARM’s interestingness measures, provides financial organizations with a detailed map of structured insights into the strength and direction of technological intersections. Originality/value The scarcity of research on patents and TC across FinTech innovations provides an opportunity for this research to be a novel approach in identifying heterogeneous technological convergence in the FinTech domain.
Lymphatic Transport and Lymphocyte Targeting of a Triglyceride Mimetic Prodrug Is Enhanced in a Large Animal Model: Studies in Greyhound Dogs

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

In previous studies, a triglyceride (TG) mimetic prodrug of the model immunomodulator mycophenolic acid (MPA) was shown to significantly enhance lymphatic transport of MPA-related species in the rat. The rat gastrointestinal tract, however, is somewhat different from that in higher order species such as dogs and humans and may underestimate lymphatic transport. Here the effectiveness of the prodrug strategy has been examined in conscious greyhound dogs, the GI physiology of which is more representative of that in humans. The bioavailability and lymphatic transport of free MPA and total MPA related materials were examined following oral administration of the parent drug (MPA) and the prodrug (2-MPA-TG) to both thoracic lymph duct cannulated and intact (noncannulated) greyhound dogs. The enrichment of free MPA in lymph nodes and lymph-derived lymphocytes was also determined to examine the efficiency of drug targeting to potential sites of action within the lymph. Via biochemical integration into a series of site-specific metabolic processes, the prodrug markedly increased (288-fold) lymphatic transport of total MPA related material (present as re-esterified 2-MPA-TG) when compared to the parent MPA and the extent of lymphatic transport was significantly greater in the dog (36.4% of the dose recovered in lymph) when compared to the previous data in the rat (13.4% of the dose). Conversion from 2-MPA-TG derivatives to parent MPA occurred in vivo, resulting in a marked increase in MPA concentrations in lymph nodes (5-6-fold) and lymph lymphocytes (21-fold), when compared to animals administered the parent drug. In conclusion, the data demonstrate that the TG prodrug of MPA facilitates efficient delivery of MPA to the lymphatic system in dogs and suggest that the TG prodrug strategy may more effectively facilitate targeted delivery in large animals than in rats.
ANTIBIOTIC PRESCRIBING PATTERN IN-PATIENT PAEDIATRICS DEPARTMENT IN A TERTIARY CARE HOSPITAL OF EASTERN INDIA

Field: Health Professions (Health Sciences)

OBJECTIVE: to nd out the extent of antimicrobial use in different indication in the paediatric in-patient department of a tertiary care hospital. METHOD: After ethical approval, a prospective, cross-sectional, descriptive epidemiological study was commence in October, 2012 - December, 2012 in the paediatric inpatient ward of Burdwan medical college and hospital. All inpatient case records were examined and there was no patient contact in any form. Patient particulars including provisional diagnosis, investigations done and drug data was recorded on a customized data collection sheet. Basic drug indicators were selected to analyze the prescribing patterns. In the present study, average number RESULT: of drugs prescribed was 3.21; 24.39% of the medicines were prescribed by generic names. A fair number of drugs (96.58%) were prescribed from the NLEM-2011. This showed that rational drug use in respect to these indicators. In present study 67.60% injection were used. More than 60% drugs were supplied from hospital. In current study, in 95% of prescription antimicrobial drugs were prescribed. On average 1.68 AMBs were prescribed per prescription per day, indicating irrationally high antimicrobial use. Most of the infective disease was treated according to standard treatment guidelines. AMBs were prescribed on clinical judgments in majority of the patients rather than taking the specimen for culture. CONCLUTION: The results of this study have provided strong evidence for the irrational high use of antibiotics and injection, which lead to increase treatment cost.
Valerie Walden. One Hundred Years of Violoncello: A History of Technique and Performance Practice, 1740–1840. Cambridge Musical Texts and Monographs. Cambridge: Cambridge University Press, 1998. xv, 311 pp. ISBN 0-521-55449-7 (hardcover)

Field: Arts and Humanities (Social Sciences)

Valerie Walden. One Hundred Years of Violoncello: A History of Technique and Performance Practice, 1740–1840. Cambridge Musical Texts and Monographs. Cambridge: Cambridge University Press, 1998. xv, 311 pp. ISBN 0-521-55449-7 (hardcover). Un article de la revue Canadian University Music Review / Revue de musique des universités canadiennes (Volume 20, numéro 2, 2000, p. 1-155) diffusée par la plateforme Érudit.
On the Degrees of Freedom of the K-User Time Correlated Broadcast Channel with Delayed CSIT

Field: Computer Science (Physical Sciences)

The Degrees of Freedom (DoF) of a K-User MISO Broadcast Channel (BC) is studied when the Transmitter (TX) has access to a delayed channel estimate in addition to an imperfect estimate of the current channel. The current estimate could be for example obtained from prediction applied on past estimates, in the case where feedback delay is within the coherence time. Building on previous recent works on this setting with two users, the estimation error of the current channel is characterized by its scaling as P at the exponent α, where α=1 (resp. α=0) corresponds to an estimate being essentially perfect (resp. useless) in terms of DoF. In this work, we contribute to the characterization of the DoF region in such a setting by deriving an outerbound for the DoF region and by providing an achievable DoF region. The achievable DoF is obtained by developing a new alignment scheme, called the Kα-MAT scheme, which builds upon both the principle of the MAT alignment scheme from Maddah-Ali and Tse and Zero-Forcing to achieve a larger DoF when the delayed CSIT received is correlated with the instantaneous channel state.
Queueing analysis of early message discard policy

Field: Decision Sciences (Social Sciences)

We consider in this paper packets which arrive according to a Poisson process into a finite queue. A group of consecutive packets forms a frame (or a message) and one then considers not only the quality of service (QoS) of a single packet but also that of the whole message. In order to improve the required QoS, either on the frame loss probabilities or on the delay, discarding mechanisms have to be used. We analyze in this paper the performance of the early message discard (EMD) policy at the buffer, which consists of (1) rejecting an entire message if upon the arrival of the first packet of the message, the buffer occupancy exceeds a threshold K, and (2) if a packet is lost, then all subsequent arrivals that belong to the same message are discarded.
645 (PS 4) VITRIFIED VS. GLAUCUS ONION (ALLIUM CEPA L.) LEAVES: A MICROSCOPIC COMPARISON

Field: Agricultural and Biological Sciences (Life Sciences)

The purpose of this study was to observe the difference in leaf surface characteristics between in vitro (vitrified and glaucus) and greenhouse grown onion leaves. Scanning electron microscopy (SEM) was used. Vitrified (hyperhydrated) leaves had little epicuticular wax and the leaf surface appeared twisted and wavy. Stomata were raised above the epidermis, appeared round instead of oblong and openings were malformed and clogged with waxy deposits. Both glaucus in vitro and greenhouse leaves had thick layers of epicuticular wax, the wax appearing to be heavier on greenhouse leaves. Stomata were oblong and sunken beneath layers of epicuticular wax. Vitrified plants died when transferred to the greenhouse under mist, while glaucus in vitro plants survived transplanting. Vitrified plantlets have a translucent, glass-like appearance and do not survive transfer to ex vitro conditions. Factors affecting vitrification will be addressed in later publications.