jimnoneill/paper-to-field-training huggingface dataset:
Aspirin Dosage - A Never-Ending Story?

Field: Medicine (Health Sciences)

Research Articles| May 26 2010 Aspirin Dosage - A Never-Ending Story? Subject Area: Cardiovascular System , Neurology and Neuroscience M.G. Hennerici M.G. Hennerici Neurologische Klinik der Universität zu Heidelberg, Klinikum Mannheim, Mannheim, Germany Search for other works by this author on: This Site PubMed Google Scholar Cerebrovasc Dis (1995) 5 (4): 308–309. https://doi.org/10.1159/000107869 Article history Received: October 15 1994 Accepted: October 17 1994 Published Online: May 26 2010 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation M.G. Hennerici; Aspirin Dosage - A Never-Ending Story?. Cerebrovasc Dis 1 April 1995; 5 (4): 308–309. https://doi.org/10.1159/000107869 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsCerebrovascular Diseases Search Advanced Search Article PDF first page preview Close Modal Keywords: Aspirin, Stroke prevention 1995Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. You do not currently have access to this content.
Removal of polycyclic aromatic hydrocarbons from sediments using sodium persulfate activated by temperature and nanoscale zero-valent iron

Field: Environmental Science (Physical Sciences)

Nano zero-valent iron (nZVI) has been successfully applied to transform/degrade contaminants in soils and water. Additionally, nZVI has been used as a catalyst to activate persulfate for the treatment of various contaminants. In this study, with the support of temperature, nZVI-persulfate oxidation system for treatment of PAH-contaminated sediments was improved significantly and the treated sediment could meet remediation goals.
Doyle, Justin Layman

Field: Arts and Humanities (Social Sciences)

Justin Layman Doyle, LL.B. Ilion, New York Phi Delta Theta; Henry Clay Law Society. "He draweth out the thread of his verbosity, finer than the staple of his argument." The pedigree of this curly-haired youth, reaching back through his sojourn at Ilion High School and Central University, at which institutions he acquired innumerable honors, is one of the most diversified that has come under our notice. At Central he was enrolled in the Law College, a member of the Deinologian Literary Society, represented the University in the Inter-collegiate Oratorical Contest in 1912, and was on the Varsity Baseball Team. Due to the fact that he has been with us only a very short time he has not come very much into the limelight. We are sorry that we have not had the pleasure of a longer acquaintance with him,, but we feel assured that he will attain distinction in his chosen profession. -The Kentuckian, 1913--------------------------------- Justin Layman Doyle (December 6, 1889 - September 28, 1988) was born in New York to Arthur Doyle and Katherine Kehoe. Doyle attended Centre College in Danville, Kentucky between 1911-1912 before receiving his LL.B. in 1913 from the University of Kentucky. He was active in debate and oratorical contests at both schools. Doyle returned to Ilion, New York to practice law. In 1917, he attended an officers' training camp at Fort Niagara. Doyle was stationed at Camp Travis, Texas and Camp Perry, Ohio during World War I. He served as 1st Lieutenant with the 18th Ammunition Train, Company C, 213. After the war, Doyle began working in sales. He lived in Texas and Colorado before eventually settling in Fort Wayne, Indiana. Doyle married Ruth Ann York in 1928.
Selective Extraction of the DM‐20 Brain Proteolipid

Field: Neuroscience (Life Sciences)

Abstract: Brain DM‐20 proteolipid was previously shown to be structurally different from the myelin major proteo‐lipid (MMPL). In an attempt to set up a large‐scale purification of DM‐20, we studied extraction of brain proteo‐lipids with mixtures of methylene chloride containing up to 80% methanol. The CH 2 Cl 2 ‐CH 3 OH (3:7, vol/vol) mixture is highly selective for the extraction of bovine brain DM‐20 compared to MMPL. Purified DM‐20 was obtained after chromatography of the extract on methylated Sephadex.
Proteomics analysis of human laryngeal cancer

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Objective To explore the molecular mechanism of occurrence and progression of human laryngeal cancer by isolating and identifying the differentially expressed proteins in human laryngeal cancer and adjacent non-carcinoma tissues.Methods Tissue samples were harvested respectively from cancerous and adjacent normal tissue of 10 laryngeal cancer patients.The expressed proteins in tumor and normal tissues were analyzed by two-dimensional gel electrophoresis.The differentially expressed proteins in tumors were also analyzed by mass spectrometry(MS).Results The proteins extracted from individual sample of both types of tissue were separated on two-dimensional gels.A total of 46 differentially expressed proteins in the tissue of laryngeal cancer were screened and 17 proteins were successfully identified by MS.Among them 5 proteins were low expressed and the other 12 proteins were overexpressed.Conclusion Significant discrepancies of protein expression existed between laryngeal cancer and adjacent normal tissues.The differentially expressed proteins may be valuable for finding the specific tumor markers of laryngeal cancer and the targets for treatment.
SOIL-INSECT toolbox: A new chamber for analysing the behaviour of herbivorous insects and tri-trophic interactions in soil

Field: Agricultural and Biological Sciences (Life Sciences)

A chamber, named SOIL-INSECT toolbox, was developed to analyse the effect of various factors on the behaviour of soil-dwelling insects. It is equipped with sensors that continuously monitor the concentration of CO2 in the different compartments of the chamber without disturbing the air balance in the soil. The chamber can be adapted to study different stimuli, including volatile compounds, both in the presence and absence of plants. The chamber was tested using the larvae of Melolontha spp., which confirmed its suitability for carrying out complex studies on insect-insect and insect-plant-microbiome interactions in a complex environment such as soil. The results of behavioural experiments using L3 larvae of Melolontha spp. in sterilized and natural soils revealed that the soil condition affected the behaviour of the larvae, likely due to its effect on the soil microbiome and physico-chemical characteristics.
Intramolecular Enzymatic Peptide Synthesis: Trypsin-mediated Coupling of the Peptide Bond between B22-Arginine and B23-Glycine in A Split Crosslinked Insulin

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The resealing of a split peptide bond (B22/23) in a crosslinked insulin derivative by a trypsin-mediated coupling reaction in Tris buffer/glycerol/dimethylsulphoxide 1 : 1 : 1 at pH 6.5 is described. The coupling yield obtained with N alpha A1, N epsilon B29-(carbonyl-bis-methionyl) insulin [OC(Met)2] was 55-60%, and reproducible yields of OC(Met)2-insulin were 40%. After removing the crosslink and purification, crystalline resynthesized insulin of high biological activity was obtained in a yield of 43% and an overall yield, based on split OC(Met)2-insulin, of 18%.
Mediator Affects Pol II Recruitment and Nucleosome Displacement at Heat Shock Protein (HSP) Genes in Saccharomyces cerevisiae

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Mediator, an evolutionarily conserved transcriptional coactivator, plays a critical role in governing both constitutive and induced levels of heat shock protein (HSP) gene expression in budding yeast. Yet how Mediator, and in particular each of its four structural modules – Head, Middle, Tail and Kinase – participates in HSP gene regulation and crosstalk with other transcriptional coactivators remains unclear. Using the conditional depletion technique termed Anchor Away, we have studied the role of two essential Middle Module subunits, Med14 and Med7, in the transcription and chromatin remodeling of HSP genes. Depletion of either subunit disrupts integrity of Mediator, as assessed by a failure of Med20 (Head) to be recruited to induced HSP genes. Pol II recruitment is also affected, and its loss parallels that of Med7. Strikingly, quantitative depletion of Med14 has a relatively modest effect on Pol II recruitment at HSP genes. Nucleosome disassembly triggered by heat shock is likewise differentially affected by loss of Med14 and Med7. These findings suggest that Mediator integrity is important, but not essential, for Pol II recruitment and chromatin remodeling upon heat shock. The interplay between Mediator and other transcriptional coactivators (SAGA, TFIID, RSC, Swi/Snf) in regulating stress‐induced transcription is under investigation. This work is supported by NSF grant MCB‐1025025 awarded to D.S.G.
Acute cerebellar vertigo in a fighter pilot.

Field: Medicine (Health Sciences)

Vertigo is a frequently encountered complaint among aviators. This complaint is usually labyrinthine in origin. We present a case of a combat jet fighter pilot who experienced a vertiginous episode during flight that nearly resulted in a mishap. Work-up revealed a dissecting aneurysm of the posterior inferior cerebellar artery. Coiling of the aneurysm was performed. This case emphasizes the importance of performing a complete vestibular evaluation in aviators with acute vertigo. Since central nervous system causes may be responsible for vertiginous events, and when undiagnosed may result in a recurrence during flight, magnetic resonance scanning should be considered in those with no obvious peripheral cause for their vertigo.
A Simple Method for Providing a Large Amplitude Mirror Oscillation in an Infrared Interferometer

Field: Physics and Astronomy (Physical Sciences)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text E. K. Pfitzer, R. P. Edwin, and R. Turner, "A Simple Method for Providing a Large Amplitude Mirror Oscillation in an Infrared Interferometer," Appl. Opt. 9, 512-513 (1970) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Cognitive and linguistic factors in the development of word definitions

Field: Psychology (Social Sciences)

ABSTRACT Three studies were carried out in order to account for development of word definitions. Study i was aimed at analysing the role of class inclusion skills and age (5– and 7–year-olds and adults) in production of definitions containing superordinate categorical terms. No differences were found between 7-year-olds who had passed a class inclusion task and those who had not passed it as regards number of definitions containing superordinates, while differences were found between younger and older children and between children and adults. Study 2 was aimed at obtaining some normative criteria on the ‘goodness’ of definitions provided in Study 1, by using adult judges. It was found that the best definitions are those which contain both categorical terms and specific information about the to-be-defined object. It was also found that adults may adjust their standard definitional criteria to the kind of interlocutor (i.e. a child or a Martian). Study 3 confirms that younger children's definitions fall far short of the adult informativeness and completeness criteria while, by the age of ten, such criteria are met. Overall results were interpreted as conforming to a progressive conventionalization of children's strategies for defining objects.
A Novel Insulin-releasing Substance, Phanoside, from the Plant Gynostemma pentaphyllum

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Extracts from Gynostemma pentaphyllum Makino (Cucurbitaceae), a Southeast Asian herb, has been reported to affect numerous activities resulting in antitumor, cholesterol-lowering, immunopotentiating, antioxidant, and hypoglycemic effects. We have isolated one active compound by ethanol extraction, distribution in n-butyl alcohol/water, solid phase extraction/separation, and several rounds of reverse phase high pressure liquid chromatography. We have shown by NMR and mass spectrometry that this active compound is a novel saponin, a gypenoside, which we have named phanoside (21-,23-epoxy-,3β-,20-,21-trihydroxydammar-24-ene-3-O-([α-d-rhamnopyranosyl(1→2)]-[β-d-glycopyranosyl(1→3)]-β-d-lyxopyranoside)), with a molecular mass of 914.5 Da. Phanoside is a dammarane-type saponin, and four stereoisomers differing in configurations at positions 21 and 23 were identified, each of which were found to stimulate insulin release from isolated rat pancreatic islets. We have also found that the stereoisomers are interconvertible. Dose-dependent insulin-releasing activities at 3.3 and 16.7 mm glucose levels were determined for the racemic mixture containing all four stereoisomers. Phanoside at 500 μm stimulates insulin release in vitro 10-fold at 3.3 mm glucose and potentiates the release almost 4-fold at 16.7 mm glucose. At these glucose levels, 2 μm glibenclamide stimulates insulin release only 2-fold. Interestingly, β-cell sensitivity to phanoside is higher at 16.7 mm than at 3.3 mm glucose, although insulin responses were significantly increased by phanoside below 125 μm only at high glucose levels. Also when given orally to rats, phanoside (40 and 80 mg/ml) improved glucose tolerance and enhanced plasma insulin levels at hyperglycemia.
Early Stages of Late Onset Alzheimer's Disease

Field: Medicine (Health Sciences)

Sixteen patients diagnosed clinically and in the laboratory as having Alzheimer's disease (AD) of late onset (>70 years of age) type, were given drugs twice a day for sixteen weeks, in a double blind design. Seven patients were given lecithin (62% phosphatidyl choline) and choline chloride and 4 patients placebo. Five patients were first treated with lecithin and choline chloride for four weeks, then L-dopa combined with benserazide hydrochloride was added for four weeks and finally L-tryptophan was also given for eight weeks (per day mean ± SEM: 26 ± 0.53 g, 53 ± 1.7 mmol, 0.71 ± 0.050 mmol, 4.1 ± 0.30 mmol). In addition, nicotinamide, sodium salicylate and benserazide hydrochloride were given (per day: 8.2 mmol, 9.4 mmol and mean ± SEM: 40 ± 2.8 mg, respectively). Side reactions were studied twice a week, behavior and chemical effects from blodd and urine samples and after 8 and 16 weeks of treatment. The three precursors, which were intended to increase cholinergic, dopaminergic and serotonergic activities in brain. Two of these precursors, lecithin and phosphatidyl choline, are found in ordinary food and the third, L-dopa, is normally produced by in vivo oxidation of L-tyrosine in food. Lecithin and choline chloride did not decrease food intake, but these substances combined with L-tryptophan did so, as did L-dopa. The lecithin and choline chloride treatment increased the fasting plasma levels of choline and low density lipoprotein cholesterol but did not change the urinary excretions of cortisol, homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), norepinephrine and epineph-rine. The addition of L-dopa and L-tryptophan increased the urinary excretions of HVA, and 5-HIAA and probably also the norepinephrine excretion. This complete multisubstitution schedule decreased the urinary excretion of epinephrine, did not change cortisol excretion and seemed to increase the urinary excretion ratios of HVA to 3-methoxy-4-hydroxy-mandelic acid (HMMA) and to HMMA + 3-methoxy-4-hydroxyphenylglycol (MHPG). These increases were, however, not significant There were no consistent effects on the cognitive functions or performance with this multisubsti tution schedule or parts of it.
Development of Driving Cycle Construction Methodology in Malaysia's Urban Road System

Field: Engineering (Physical Sciences)

This paper presents a driving cycle construction methodology in Malaysia's urban road system by utilizing on-road data collection from Kuala Lumpur. Micro trip cycle construction approach is use in this study to construct driving cycle for Malaysia's urban road system. The driving cycle constructed using this approach is a transient driving cycle similar to WLTC, JC08 and FTP-75 driving cycles, which is experimental based and are more reflecting the actual driving conditions hence has more representatives comparing to polygonal driving cycles such as NEDC and J10-15 mode driving cycles. It was found that the characteristic of the newly developed driving cycle in Malaysia's urban road system has small relative percentages when compared to the target parameters (whole database) hence it is best represent the driving condition in Kuala Lumpur. The cycle construction methodology proposed in this study is appropriate for developing urban driving cycles, though some improvements need to be considered to increase the representativeness of the driving cycle.
Lincoln in Scotland: A Gift of the Gilded Age

Field: Arts and Humanities (Social Sciences)

On August 21, 1893, a bronze stature of Abraham Lincoln was erected in the heart of Edinburgh, Scotland. This article examines the story of this monument and the motivations of the men who erected it, as a way of understanding Lincoln’s legacy on Scottish shores. Further, this gift from America to Scotland can be understood as a symbol of Gilded Age transatlantic relations.
Transient Stability Enhancement of Wind Farms using Photovoltaic Solar Plant as STATCOM

Field: Energy (Physical Sciences)

The aim of this study is to investigate the improvement of the performances and transient stability of grid connected Squirrel Cage Induction Generator based on Wind Farm (SCIG-WF) by using a new coordinated control between Grid Side Converter (GSC) of the Doubly Fed Induction Generator (DFIG) and photovoltaic solar plant converter (PV-SPC) as STATCOM. Thereby, the reactive power required by the SCIG-WF can be supplied either by the DFIGs (during normal condition) and with the PV-STATCOM during grid disturbances. This control strategy can fulfill the grid codes requirement such low voltage ride through capability by ensuring a no uninterrupted operation of the wind farm. The proposed control scheme is simulated by means of MATLAB/Simulink platform, based on a detailed system model. Through the simulated results, we can conclude that the proposed control for PV-SPC to operate as STATCOM is validated and the performances of the system are improved during normal and transient conditions.
Role of Probiotics in Reducing GERD

Field: Medicine (Health Sciences)

Probiotic is little known for its benefits on upper gastrointestinal health. The objective of this systematicreview was to examine the efficacy of probiotics in alleviating the frequency and severity of symptoms ingastroesophageal reflux disease (GERD) in the general adult population.. In total, 13 prospective studiesthat were published in 12 articles were included in the analysis and scored per the Jadad scale as high- (fivestudies), medium- (two), and low- (six) quality. One article reported on two probiotic groups; thus, 14comparisons were included in the selected studies, of which 11 (79%) reported positive benefits of probioticson symptoms of GERD. Five out of 11 positive outcomes (45%) noted benefits on reflux symptoms: threenoted reduced regurgitation; improvements in reflux or heartburn were seen in one study; five (45%) sawimprovements in dyspepsia symptoms; and nine (81%) saw improvements in other upper gastrointestinalsymptoms, such as nausea (three studies), abdominal pain (five), and gas-related symptoms (four), such asbelching, gurgling, and burping. In conclusion, probiotic use can be beneficial for GERD symptoms, suchas regurgitation and heartburn.
Transformation of Malus × domestica with MhRAR1 and MhSGT1 Genes from Malus hupehensis for Resistance of Botryosphaeria berengeriana

Field: Agricultural and Biological Sciences (Life Sciences)

RAR1 and SGT1 were identified as required components in some signaling pathways mediated by disease resistance (R) genes in many plant species,and they function between the downstream of R protein and reactive oxygen. To understand the expression characteristics and resistant function of MhRAR1 and MhSGT1 in susceptible variety,the two genes were transferred respectively into the Fuji apple by Agrobacterium tumefaciens-mediated method. After PCR and RT-PCR amplifications on Hyg positive plants,6 MhRAR1 strains and 3 MhSGT1 strains were screened. Infected by Botryosphaeria berengeriana, the transgenic plants displayed more rapidly increase on all antioxidant enzymes (SOD/POD/CAT) activities and gentle changing waves of MDA content. It further illustrated that RAR1 and SGT1 act on the reaction of reactive oxygen species and the process of membrane reaction,as well as promote the resistant to external infringed reaction in apple.