jimnoneill/paper-to-field-training huggingface dataset:
Analyzing the Influence of Occupational Licensing Duration and Grandfathering on Wage Determination

Field: Economics, Econometrics and Finance (Social Sciences)

The length of time from the implementation of an occupational licensing statute (i.e., licensing duration) may matter in influencing labor‐market outcomes as entry requirements evolve. In addition, states enact grandfather clauses that allow existing workers to continue employment following these regulations, while ratcheting up requirements to increase entry costs for new entrants. We analyze the labor‐market influence of the duration of occupational licensing statutes for fifteen state universally licensed occupations over a 75‐year period. We find a positive nonlinear wage effect for licensing duration. Further, we find that occupational licensing raises the wages of grandfathered workers by almost 5 percent. The licensed occupations, however, exhibit heterogeneity in outcomes. Duration of occupational licensing influences wage determination when measured over longer time periods.
Urban Form and Structure Explain Variability in Spatial Inequality of Property Flood Risk among US Counties

Field: Environmental Science (Physical Sciences)

Understanding the relationship between urban form and structure and spatial variation of property flood risk has been a longstanding challenge in urban planning and city flood risk management. Yet limited data-driven insights exist regarding the extent to which variation in spatial inequality of property flood risk in cities can be explained by heterogenous features of urban form and structure. In this study, we explore eight key features (i.e., population density, point of interest density, road density, minority segregation, income segregation, urban centrality index, gross domestic product, and human mobility index) related to urban form and structure to explain variability in spatial inequality of property flood risk among 2567 US counties. Using rich datasets related to property flood risk, we quantify spatial inequality in property flood risk and delineate features of urban form and structure using high-resolution human mobility and facility distribution data. We identify significant variation in spatial inequality of property flood risk among US counties with coastline and metropolitan counties having the greatest spatial inequality of property flood risk. The results also reveal variations in spatial inequality of property flood risk can be effectively explained based on principal components of development density, economic activity, and centrality and segregation. Using a classification and regression tree model, we demonstrate how these principal components interact and form pathways that explain levels of spatial inequality in property flood risk in US counties. The findings offer important insights for the understanding of the complex interplay between urban form and structure and spatial inequality of property flood risk and have important implications for integrated urban design strategies to address property flood risk as cities continue to expand and develop.
Method to orient cardiac tissue specimens for uniaxial mechanical testing with long axis parallel to sarcomeres

Field: Medicine (Health Sciences)

Muscle tissue is strongly anisotropic, and uniaxial tests of muscle are typically performed by stretching parallel to the myofiber direction. Dissection of a properly aligned cardiac muscle specimen for such uniaxial biomechanical tests is often a difficult task. When tissue samples are derived from a frozen block of myocardium excised from the ventricular wall, there are often few superficial clues to the underlying orientation of the sarcomere chains. Moreover, the direction of the sarcomeres changes as one travels through the thickness of the heart wall, and this further complicates the task. A technique for dissecting a small specimen with proper myofiber orientation is demonstrated below, in particular, for uniaxial stress/strain analysis of non-contracting myocardial tissue.
Low-Pathogenicity Variant of Lymphocytic Choriomeningitis Virus

Field: Immunology and Microbiology (Life Sciences)

A noncytopathic virus has been isolated from a line of strain L mouse fibroblasts infected with lymphocytic choriomeningitis (LCM). This virus has low pathogenicity for mice and renders them immune to intracerebral challenge with virulent LCM virus.
Whosecough: In-the-Wild Cougher Verification Using Multitask Learning

Field: Computer Science (Physical Sciences)

Current automatic cough counting systems can determine how many coughs are present in an audio recording. However, they cannot determine who produced the cough. This limits their usefulness as most systems are deployed in locations with multiple people (i.e., a smart home device in a four-person home). Previous models trained solely on speech performed reasonably well on forced coughs [1]. By incorporating coughs into the training data, the model performance should improve. However, since limited natural cough data exists, training on coughs can lead to model overfitting. In this work, we overcome this problem by using multitask learning, where the second task is speaker verification. Our model achieves 82.15% classification accuracy amongst four users on a natural, in-the-wild cough dataset, outperforming human evaluators on average by 9.82%.
Adjuvants and autoimmunity

Field: Immunology and Microbiology (Life Sciences)

Some adjuvants may exert adverse effects upon injection or, on the other hand, may not trigger a full immunological reaction. The mechanisms underlying adjuvant adverse effects are under renewed scrutiny because of the enormous implications for vaccine development. In the search for new and safer adjuvants, several new adjuvants were developed by pharmaceutical companies utilizing new immunological and chemical innovations. The ability of the immune system to recognize molecules that are broadly shared by pathogens is, in part, due to the presence of special immune receptors called toll-like receptors (TLRs) that are expressed on leukocyte membranes. The very fact that TLR activation leads to adaptive immune responses to foreign entities explains why so many adjuvants used today in vaccinations are developed to mimic TLR ligands. Alongside their supportive role, adjuvants were found to inflict by themselves an illness of autoimmune nature, defined as ‘the adjuvant diseases’. The debatable question of silicone as an adjuvant and connective tissue diseases, as well as the Gulf War syndrome and macrophagic myofaciitis which followed multiple injections of aluminium-based vaccines, are presented here. Owing to the adverse effects exerted by adjuvants, there is no doubt that safer adjuvants need to be developed and incorporated into future vaccines. Other needs in light of new vaccine technologies are adjuvants suitable for use with mucosally delivered vaccines, DNA vaccines, cancer and autoimmunity vaccines. In particular, there is demand for safe and non-toxic adjuvants able to stimulate cellular (Th1) immunity. More adjuvants were approved to date besides alum for human vaccines, including MF59 in some viral vaccines, MPL, AS04, AS01B and AS02A against viral and parasitic infections, virosomes for HBV, HPV and HAV, and cholera toxin for cholera. Perhaps future adjuvants occupying other putative receptors will be employed to bypass the TLR signaling pathway completely in order to circumvent common side effects of adjuvant-activated TLRs such as local inflammation and the general malaise felt because of the costly whole-body immune response to antigen. Lupus (2009) 18, 1217—1225.
An improved baseline model for a human arterial network to study the impact of aneurysms on pressure‐flow waveforms

Field: Engineering (Physical Sciences)

SUMMARY In this study, an improved and robust one‐dimensional human arterial network model is presented. The one‐dimensional blood flow equations are solved using the Taylor‐locally conservative Galerkin finite element method. The model improvements are carried out by adopting parts of the physical models from different authors to establish an accurate baseline model. The predicted pressure‐flow waveforms at various monitoring positions are compared against in vivo measurements from published works. The results obtained show that wave shapes predicted are similar to that of the experimental data and exhibit a good overall agreement with measured waveforms. Finally, computational studies on the influence of an abdominal aortic aneurysm are presented. The presence of aneurysms results in a significant change in the waveforms throughout the network. Copyright © 2012 John Wiley & Sons, Ltd.
Possibility of N or P limitation for planktonic cladocerans: An experimental test

Field: Environmental Science (Physical Sciences)

Threshold food N : C or P : C ratios, below which net production is N or P limited, were calculated for two cladocerans, Daphnia galeata and Bosmina longirostris, based on the N and P contents of body tissue and the C balance between ingestion and net production rates under experimental conditions with various food concentrations from 0.05 to 2.50 mg C liter ‒1 . With changing food concentration, the threshold N : C and P : C ratios for D. galeata changed in weight ratio from 0.039 to 0.077 and 0.0067 to 0.0120, respectively, with the lowest value at the high food concentration. Changes in threshold ratios for B. longirostris, however, were small and mean values were 0.085 and 0.0080 for the N : C and P : C ratios. As a result, the threshold N : C ratio for D. galeata was lower than for B. longirostris at high food concentrations, while the P : C ratio for B. longirostris was lower than for D. galeata at lower food concentrations. Although the threshold elemental ratios calculated here are theoretically minimum estimates, they were higher than the lower end of the sestonic elemental ratios in some lakes, suggesting that it is not unusual for these cladocerans to be N or P limited at certain periods of the year. Sestonic elemental ratios may have potential importance in determining the community structure of zooplankton.
NASA's In Space Propulsion Technology Program Accomplishments and Lessons Learned

Field: Energy (Physical Sciences)

NASA's In-Space Propulsion Technology (ISPT) Program was managed for 5 years at the NASA MSFC and significant strides were made in the advancement of key transportation technologies that will enable or enhance future robotic science and deep space exploration missions. At the program's inception, a set of technology investment priorities were established using an NASA-wide, mission-driven prioritization process and, for the most part, these priorities changed little - thus allowing a consistent framework in which to fund and manage technology development. Technologies in the portfolio included aerocapture, advanced chemical propulsion, solar electric propulsion, solar sail propulsion, electrodynamic and momentum transfer tethers, and various very advanced propulsion technologies with significantly lower technology readiness. The program invested in technologies that have the potential to revolutionize the robotic exploration of deep space. For robotic exploration and science missions, increased efficiencies of future propulsion systems are critical to reduce overall life-cycle costs and, in some cases, enable missions previously considered impossible. Continued reliance on conventional chemical propulsion alone will not enable the robust exploration of deep space - the maximum theoretical efficiencies have almost been reached and they are insufficient to meet needs for many ambitious science missions currently being considered. By developing the capability to support mid-term robotic mission needs, the program was to lay the technological foundation for travel to nearby interstellar space. The ambitious goals of the program at its inception included supporting the development of technologies that could support all of NASA's missions, both human and robotic. As time went on and budgets were never as high as planned, the scope of the program was reduced almost every year, forcing the elimination of not only the broader goals of the initial program, but also of funding for over half of the technologies in the original portfolio. In addition, the frequency at which the application requirements for the program changed exceeded the development time required to mature technologies: forcing sometimes radical rescoping of research efforts already halfway (or more) to completion. At the end of its fifth year, both the scope and funding of the program were at a minimum despite the program successfully meeting all of it's initial high priority objectives. This paper will describe the program, its requirements, technology portfolio, and technology maturation processes. Also discussed will be the major technology milestones achieved and the lessons learned from managing a $100M+ technology program.
Genetic control of cholinesterase activity in horse serum

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Summary The cholinesterase activity in horse serum was shown to be controlled by four co‐dominant autosomal alleles, Ch A , Ch B , Ch c and Ch D . The respective alleles controlled an activity of approximately 40, 76, 126 and 155 units. Nine phenotypes with different enzyme levels were distinguished. Family data with 11 stallions, 108 mares and 128 offspring were consistent with the genetic theory. The gene frequencies in the North Swedish horse breed were 0.32, 0.42, 0.13 and 0.13, respectively.
Na/K/Cl cotransport in cultured human fibroblasts.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The transport characteristics and regulation of the Na/K/Cl cotransport system were investigated in cultured human fibroblasts (HSWP cells). The existence of the system was documented by the finding that digitoxin-insensitive K+ influx was dependent upon the presence of both Na+ and Cl- in the extracellular milieu. It was found that only Br- could partially substitute for Cl-, with SCN-, I-, acetate, and gluconate being ineffective. Li+ could partially substitute for Na+; however, choline was without effect. The shape of the titration curves for K+ influx versus extracellular Cl- concentration was dependent upon the substituted anion. Furthermore, the apparent Km for Cl- at saturating [K+]o and [Na+]o, was also dependent upon the substituted anion and ranged from 30 mM (gluconate substitution) to 100 mM (acetate substitution). The titration curves for K+ influx versus extracellular Na+ concentration displayed hyperbolic kinetics and the apparent Km = 15 mM at saturating [K+]o. The curve for K+ influx versus extracellular K+ concentration was a hyperbola and the apparent Km for K+ = 3 mM at saturating [Na+]o. The digitoxin-insensitive K+ flux was found to be sensitive to related 5-sulfamoylbenzoic acid derivatives, commonly known as "loop" diuretics and to be insensitive to both: amiloride (3,5-diamino-N-(aminoiminomethyl)-6-chloropyrazinecarboxamide++ +) and 4-acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid. The Na/K/Cl cotransport system was not stimulated by serum, but was slightly stimulated by two peptide mitogens. Furthermore, agents which cause an elevation in cellular cyclic AMP levels were found to be potent inhibitors of cotransport.
Retroperitoneal Bleeding and Arteriovenous Fistula after Percutaneous Coronary Intervention Successfully Treated with Intravascular Ultrasound-guided Covered Stent Implantation

Field: Medicine (Health Sciences)

The major puncture-site complications of the transfemoral approach are retroperitoneal bleeding (RPB), arteriovenous (AV) fistula, and arterial pseudoaneurysm. Although the management of RPB and AV fistula depends on individual cases, our experience shows that the use of a covered stent with intravascular ultrasound (IVUS) guidance can successfully manage percutaneous coronary intervention-associated RPB and AV fistula. IVUS guidance can therefore make it easy to use an optimal-size covered stent.
Using Lagging and Leading Indicators and the Importance of Benchmarking Contractor Performance

Field: Decision Sciences (Social Sciences)

Abstract Statistics show what gets measured gets done. Measuring and benchmarking contractor performance is a key driver of continual health and safety efforts in the oil and gas industry. Our research, drawn from 15 years of global experience with 450+ Clients and 60,000+ contractors, highlights the key leading and lagging performance indicators used in the oil and gas industry and introduces leading edge methods to identify vital Key Performance Indicators. Monitoring and benchmarking tools such as collection and tracking of contractor work hours, incident rates, action items, evaluations and written health and safety procedures are all crucial to effective ongoing management of contractor performance. In addition, having a system for contractors to be able to identify potential safety system gaps that may need their attention, can further drive improvements. Our paper demonstrates some basic data trending and analysis methods plus leading edge methods, including regression and correlation statistical analysis approaches being used in the industry to identify factors that are positively or negatively associated with increased or decreased health and safety performance. Such methods are useful in identifying vital Key Performance Indicators (KPI's) to measure and monitor. Real world analytical examples will be presented and discussed. Using data driven hiring decisions is a vital part of any prevention plan. Through use of a system for managing and evaluating contractor safety data, Clients have seen significant improvement in their contractors' performance. Case studies of clients who have seen improvement of more than 90% for their contractors' incident rates will be discussed.
The current status of Chukar (Alectoris chukar J. E. Gray, 1830) in Armenia

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract The Chukar Alectoris chukar is one of the most popular game birds of Armenia, but there is no governmental monitoring programme for that exploited species. We carried out national surveys in 2003–2019 and estimate the current occupied range of the Chukar in Armenia as 5,082 km 2 (17% of the country). In 2019, we estimate Chukar population size at 12,472 breeding pairs (95% CL: 10,266–14,677). Its population trend shows a moderate decline underlying strong annual fluctuations. In Armenia, the Chukar occurs on 20 public hunting lands covering 2,414 km 2 in total. Its abundance on these public hunting lands is estimated to 5,558 breeding pairs in 2019 (95% CL: 3,656–7,460). Surveys of the seven Hunters’ Unions of Armenia found that there are 10,000 to 20,000 active hunters. The number of hunting permits issued annually increased ten-fold between 2016 and 2019, exceeding the capacity of the public hunting lands in 2019. A hunter survey found that each Chukar hunter shot on average (± SD) 5.88±3.05 birds in the 2018/19 season, which extrapolates to 17,052–34,104 shot specimens of Chukar (at least 46% of autumn numbers). Current hunting management practice is thus unsustainable and we provide recommendations for sustainable approaches that should replace it urgently.
Lidar‐derived estimate and uncertainty of carbon sink in successional phases of woody encroachment

Field: Environmental Science (Physical Sciences)

Abstract Woody encroachment is a globally occurring phenomenon that contributes to the global carbon sink. The magnitude of this contribution needs to be estimated at regional and local scales to address uncertainties present in the global‐ and continental‐scale estimates, and guide regional policy and management in balancing restoration activities, including removal of woody plants, with greenhouse gas mitigation goals. The objective of this study was to estimate carbon stored in various successional phases of woody encroachment. Using lidar measurements of individual trees, we present high‐resolution estimates of aboveground carbon storage in juniper woodlands. Segmentation analysis of lidar point cloud data identified a total of 60,628 juniper tree crowns across four watersheds. Tree heights, canopy cover, and density derived from lidar were strongly correlated with field measurements of 2613 juniper stems measured in 85 plots (30 × 30 m). Aboveground total biomass of individual trees was estimated using a regression model with lidar‐derived height and crown area as predictors (Adj. R 2 = 0.76, p < 0.001, RMSE = 0.58 kg). The predicted mean aboveground woody carbon storage for the study area was 677 g/m 2 . Uncertainty in carbon storage estimates was examined with a Monte Carlo approach that addressed major error sources. Ranges predicted with uncertainty analysis in the mean, individual tree, aboveground woody C, and associated standard deviation were 0.35 – 143.6 kg and 0.5 – 1.25 kg, respectively. Later successional phases of woody encroachment had, on average, twice the aboveground carbon relative to earlier phases. Woody encroachment might be more successfully managed and balanced with carbon storage goals by identifying priority areas in earlier phases of encroachment where intensive treatments are most effective.
Selecting Single-Nucleotide Polymorphisms for Association Studies With SNPbrowser™ Software

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The design of genetic association studies using single-nucleotide polymorphisms (SNPs) requires the selection of subsets of the variants providing high statistical power at a reasonable cost. SNPs must be selected to maximize the probability that a causative mutation is in linkage disequilibrium (LD) with at least one marker genotyped in the study. The HapMap Project performed a genome-wide survey of genetic variation with over 3 million SNPs typed in four populations, providing a rich resource to inform the design of association studies. A number of strategies have been proposed for the selection of SNPs based on observed LD, including construction of metric LD maps and the selection of haplotype-tagging SNPs. Power calculations are important at the study design stage to ensure successful results. Integrating these methods and annotations can be challenging: the algorithms required to implement these methods are complex to deploy, and all the necessary data and annotations are deposited in disparate databases. Here, we review the typical workflows for the selection of markers for association studies utilizing the SNPbrowser™ software, a freely available, stand-alone application that incorporates the HapMap database together with gene and SNP annotations. Selected SNPs are screened for their conversion potential to genotyping platforms, expediting the set up of genetic studies with an increased probability of success.
The Endangerment of Trees: A Provacative Analysis of Online Archival Finding Aids

Field: Arts and Humanities (Social Sciences)

The author contemplates the future of the archival finding aid on the occasion of the tenth anniversary of Encoded Archival Description, a standard for encoding archival finding aids for use in an online environment. The author posits that standards for multi-level, hierarchical description in archival finding aids may conflict with how web search engines index finding aids as well as the requirements for describing digital-born materials of the future.