jimnoneill/paper-to-field-training huggingface dataset:
Personalities of Russian animation: synergetic films of Alexander Svirsky

Field: Arts and Humanities (Social Sciences)

Russian animation director Alexander Svirsky is known for his desire to push the boundaries of animation and avoid traditional conventions, often rejecting the standards accepted in the animation industry. His works are a synthesis of artistic techniques, where the author uses images and symbols, harmoniously intertwining graphics with a musical accompaniment. The relevance of the study is due to the fact that the director's works deserve deep analysis in order to identify promising types of artistic forms in domestic animation cinema. The object of the study is the animated films of Alexander Svirsky, a visionary artist with a unique view of the nature of animation. The subject of the study is the peculiarity of the director’s synergetic animation, which manifests itself, in particular, in the integration of visual and sound spaces into a holistic artistic image according to the type of associative flow. The work uses a complex of general scientific (comparison, analysis, generalization) and special methods (visual-iconic, artistic-evaluative). In the analysis of animated films, descriptive-analytical and structural-semantic methods were used. The scientific novelty of the work is due to the fact that in art studies the analysis of the director's work has not been given sufficient attention, while the films he creates are highly appreciated at animation festivals. The author's contribution to the study of the topic is a detailed analysis of the director's work using some of his works as an example. The main conclusions of the conducted research are that the artistic form of Alexander Svirsky's animated films predominantly belongs to the promising, actively developed in the media space, flat-conceptual type, resonating with the perception of audiovisual content by the younger generation of viewers.
Application of probiotic preparation Vetom 3.22 in disease of girl cross with herpes virus type 2 (CyHV-2)

Field: Veterinary (Health Sciences)

The effect of the probiotic drug Vetom 3.22 on the body of silver crucian carp when used as a feed additive against the background of an acute course of the cyprinid herpes virus type 2 (CyHV-2) was shown. Diagnosis of this disease before the manifestation of characteristic clinical signs is difficult, and specific treatment has not been developed, so therapy that supports immunity is used. The physiological state of goldfish during the experiment was assessed based on the results of hematological analysis. Individuals not infected with the specified virus were selected as a control group. Research results have shown that Vetom 3.22 has a beneficial effect on the fish body: the immune response to the disease with cyprinid herpes virus type 2 (CyHV-2) is increased by improving the process of leukopoiesis, metabolism is stimulated by an increase in the number of red blood cells. The drug can be successfully used as a biologically active additive to feed, including as an adjunct in the treatment of fish for diseases for which no drug measures have been developed. However, it should be taken into account that the drug Vetom 3.22 is not a therapeutic agent, therefore, in case of serious fish diseases, in addition to it, the use of specialized drugs is required. The results obtained can be used to prepare practical recommendations on measures to combat acute disease in aquaculture.
Lift and drag coefficient versus angle of attack for a flying snake cross-section

Field: Engineering (Physical Sciences)

Plots of the lift coefficient and drag coefficient of a flying snake cross-section, obtained from two-dimensional simulations using an immersed boundary method (cuIBM). We provide PDF files of the final plots, as they will appear in our paper "Lift and Wakes of Flying Snakes," submitted for peer review. The preprint of the paper is found at: http://arxiv.org/abs/1309.2969 The file bundle also includes the data set and the plotting scripts. The README file explains how to run the plotting scripts, as well as describing other file bundles that are released as supplementary materials for our paper. The data and figures are here shared under CC-BY, and will be thus referenced in the Figure captions in the paper.
DESIGN AND IN VITRO EVALUATION OF NOVEL NICORANDIL SUSTAINED RELEASE MATRIX TABLETS BASED ON COMBINATION OF HYDROPHILIC AND HYDROPHOBIC MATRIX SYSTEM

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Conventional drug delivery system for treating the anginal are not much effective as the drug do not reach the site of action in appropriate concentration. Thus an effective and safe therapy of this anginal disorder using specific drug delivery system is a challenging task to the pharmaceutical technologists. Most commonly used method of modulating the drug release is to include it in a matrix system. Because of their flexibility, hydrophilic polymer matrix systems are widely used in oral controlled drug delivery to obtain a desirable drug release profile, cost-effectiveness, and broad regulatory acceptance. Formulation of Nicorandil matrix tablet was prepared by the polymers blend with to get desirable release profile. Formulated tablets were also characterized by parameters like thickness, weight variation test, drug content uniformity, hardness, friability and the in-vitro release rate profile was compared with the marketed product’s release profile with the help of similarity factor (f2) value. Formulation prepared with HPMC K200M: Eudragit RSPO (1:1) indicates 94.46% of drug release at 22 hrs and it has similarity factor (f2) value 68.07. Hydrophilic and Hydrophobic polymer combination showed 22 hrs release using combination of hydrophilic or hydrophobic polymers.
Aneurysm of the Renal Artery

Field: Medicine (Health Sciences)

No AccessJournal of Urology1 Nov 1956Aneurysm of the Renal Artery Samuel Malisoff, and M. Cerruti Samuel MalisoffSamuel Malisoff More articles by this author , and M. CerrutiM. Cerruti More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)66733-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1956 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited BySmith J and Hinman F (2018) Intrarenal Arterial AneurysmsJournal of Urology, VOL. 97, NO. 6, (990-996), Online publication date: 1-Jun-1967. Volume 76Issue 5November 1956Page: 542-549 Advertisement Copyright & Permissions© 1956 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Samuel Malisoff More articles by this author M. Cerruti More articles by this author Expand All Advertisement PDF DownloadLoading ...
Monitoring System for Evaluation of Operator Functional Status on Sea Ships

Field: Health Professions (Health Sciences)

This paper introduces the basic concept of a new developed web-based databank for an assessment of seafarers’ functional status during the sea missions. The Web system is based on client-server architecture and the international open source technologies including Apache web server, PHP scripts and MySQL database. The paper focuses on the aspects and first results of the initial practical realization of the web-based databank. The main operational advantage of the developed system is the capability to on-line handle up to a dozen users at the same time. The system includes administrative data and questionnaires. Electronic data entry saves the time and material resources.
Design of a high-tech vending machine

Field: Engineering (Physical Sciences)

Imagine, paying and placing an order in a food outlet only to wait for an extra twenty to thirty minutes to get the ordered products. How tiring. This is the current situation in different food outlets and shops. What if we could save time by 75% to 83% and get an order in five minutes or less? This can be achieved by the design and development of a fully fletched high–tech vending machine. Current vending machine owners are facing challenges from hacking and vandalism. The aim of this paper is to design a high-tech vending machine that can dispense a variety of products at the same time. The machine uses fingerprint sensors and other high technological features for security and user-friendliness. The security system which uses biometrics for opening and closing doors was interrogated and used. An advertising platform was developed using HTML, JavaScript and CSS to cater for different products on offer. The alarm system is interfaced with a servo motor and a buzzer for providing added security. Sublime Text was used for creating a website and XAMPP was used for port forwarding. The result is a fully fletched vending machine that can safely vend about fifteen products or more all housed in a robust cabin.
Efficient Data Collection for IoT Services in Edge Computing Environment

Field: Computer Science (Physical Sciences)

The Internet of Things (IoT) represents a major change in sensor data collection. It is predicted that 50 billion devices will produce a large amount of data by 2020. This data needs to be stored efficiently so that it can be efficiently retrieved on demand for real-time application. Most of the Cloud-IoT solutions focus on centralized data collection and storage which is not appropriate for efficient data collection and utilization. For addressing such diverse set of requirements,resources are placed near to the data sources for processing and fast real-time decision making instead of sending all the data to the Cloud. The gateway is such a type of edge device that collects data from smart sensors, but it does not have any pre-processing or decision-making capabilities. Therefore, the gateway has to be made smarter with Fog capabilities and named as Fog Smart Gateway(FSG). We represent the distributed Cloud-IoT solution where data optimally distributed among mini-clouds/Fog nodes. The processing of IoT traffic is taken care of by Virtual Machines(VMs) facilitated by distributed mini-clouds/Fog nodes and located within the edge devices. We optimized the number of mini-clouds placement to reduce the total latency and power consumption induced by traffic aggregation and processing. However, there has been little research on fog node placement. Our results show that the optimal distribution of mini-clouds in the IoT network could yield a total energy saving and reduction in latency compared to processing IoT data in a conventional cloud system.
Testimony and Transcription in the Life of Sarah Ryan

Field: Arts and Humanities (Social Sciences)

The life of Sarah Ryan included a family break-up, a period of domestic service, abusive 'marriages' to three husbands (two simultaneously), a Methodist conversion, and finally her self-reinvention as a preacher and co-founder of the Leytonstone orphanage in 1763. Her story has been marginalised within Methodist historiography, but it is preserved in the archive as a consequence of Mary Fletcher's commitment to recording the life of her companion. Ryan seems to have dictated her personal history to Fletcher around 1767, and 'Account of Sarah Ryan' (allegedly 'taken from her own mouth') provides a narrative of her experiences from childhood up until her Methodist conversion. Fletcher includes an authorial note clarifying her relationship to Ryan and the nature of the text, and transcribes extracts from Ryan's diary and correspondence. The patchwork of texts also includes 'Some Further Account of Mrs Ryan' as well as several autobiographical fragments. Aspects of this collection have found their way into print, but the full story of Ryan's life could not be assimilated into the Methodist canon. Instead, her experiences appear in excerpts published in the Arminian Magazine, including a fifteen-page spiritual narrative in 1779, a selection of correspondence between Ryan and John Wesley serialised in 1782, and diary extracts that appeared in 1806.1 Ryan's experiences were therefore valued as a series of isolated instants that illustrated stages on the path to salvation, but publication was premised on making the material details of her unconventional life invisible.
Determination of the Membrane Topology of the PORCN O‐Acyl Transferase

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

WNT signaling is critical for proper embryonic development and adult tissue homeostasis. WNT proteins require palmitoylation for optimal secretion and receptor binding. Porcupine (PORCN), a membrane bound O‐acyltransferase (MBOAT) family member is the protein that palmitoylates WNT. PORCN is localized to the Endoplasmic Reticulum (ER). Though PORCN is required for proper tissue patterning in developing embryos, its membrane topology is poorly understood. Determining the topology of PORCN may have useful applications in areas of embryonic development studies. Although numerous bioinformatics algorithms that predict membrane topology are available, no clear consensus for the topology of PORCN has emerged. Therefore, our goal is to experimentally determine the topology of PORCN. To determine topology, we developed two strategies. The first strategy utilized differential solubilization and immunofluorescent imaging of single, and dual tagged PORCN variants. Results from single Myc‐tagged N‐and C‐terminus PORCN variants in transfected COS‐7 cells orient the N‐terminus in the ER lumen, and the C‐terminus in the cytosol. To further determine topology, we developed twelve dual tagged PORCN variants with Myc epitopes within predicted loops, and a C‐terminal 3X FLAG tag. The construction of dual tagged variants provided us with qualitative information, as well as quantitative values using Mander's coefficients of colocalization. Our studies show that five of the PORCN variant loops exhibit cytosolic orientation while one loop was oriented toward the lumen. As a control, we showed that the N‐ and C‐terminal tags remained lumenal and cytosolic, respectively. However, the remaining constructs provided conflicting results. Additionally, a PORCN antibody was generated against an immunogenic region that includes residues 282–303. Immunofluorescent imaging and colocalization quantitation orient this epitope towards the cytosol. As a second strategy, we developed ten mutants which resulted in the introduction of ectopic consensus sites for the addition of N‐linked carbohydrates (NxT/NxS). These PORCN mutants were transfected into HEK‐293T cells and subjected to Western blot analysis to identify glycosylated variants. This analysis identified two glycosylated residues at A134N and D283N, which indicates localization of these two residues to the lumen of the ER. Intriguingly, these results do not agree with those from our differential solubilization studies. We are now carrying out additional controls to help us distinguish between these two results. Support or Funding Information NIH‐MARC T34‐GM008574
Application of Genetic Algorithm in Low Altitude Penetration

Field: Computer Science (Physical Sciences)

Considering the calculation complexity and convergence in low altitude penetration route planning of helicopter,the basic principle of genetic algorithm is introduced,the performance specifications of route optimization are analyzed.The genetic algorithm is applied to route planning,and chromosome coding of route is performed.The initial population is generated according to the random function,and according to the size of the fitness function,selection,crossover and mutation are conducted.The optimal route is exported when the algorithm termination condition is met.Simulation result shows that the optimal route planned by using the improved genetic algorithm can effectively avoid threats and terrain.
Metformin Is a Pyridoxal-5′-phosphate (PLP)-Competitive Inhibitor of SHMT2

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The anticancer actions of the biguanide metformin involve the functioning of the serine/glycine one-carbon metabolic network. We report that metformin directly and specifically targets the enzymatic activity of mitochondrial serine hydroxymethyltransferase (SHMT2). In vitro competitive binding assays with human recombinant SHMT1 and SHMT2 isoforms revealed that metformin preferentially inhibits SHMT2 activity by a non-catalytic mechanism. Computational docking coupled with molecular dynamics simulation predicted that metformin could occupy the cofactor pyridoxal-5′-phosphate (PLP) cavity and destabilize the formation of catalytically active SHMT2 oligomers. Differential scanning fluorimetry-based biophysical screening confirmed that metformin diminishes the capacity of PLP to promote the conversion of SHMT2 from an inactive, open state to a highly ordered, catalytically competent closed state. CRISPR/Cas9-based disruption of SHMT2, but not of SHMT1, prevented metformin from inhibiting total SHMT activity in cancer cell lines. Isotope tracing studies in SHMT1 knock-out cells confirmed that metformin decreased the SHMT2-channeled serine-to-formate flux and restricted the formate utilization in thymidylate synthesis upon overexpression of the metformin-unresponsive yeast equivalent of mitochondrial complex I (mCI). While maintaining its capacity to inhibit mitochondrial oxidative phosphorylation, metformin lost its cytotoxic and antiproliferative activity in SHMT2-null cancer cells unable to produce energy-rich NADH or FADH2 molecules from tricarboxylic acid cycle (TCA) metabolites. As currently available SHMT2 inhibitors have not yet reached the clinic, our current data establishing the structural and mechanistic bases of metformin as a small-molecule, PLP-competitive inhibitor of the SHMT2 activating oligomerization should benefit future discovery of biguanide skeleton-based novel SHMT2 inhibitors in cancer prevention and treatment.
SOLUBILIZATION AND FUNCTIONAL PROPERTIES OF MOTH BEAN (VIGNA ACONITIFOLIA (Jacq.) Marechal AND HORSE GRAM (MACROTYLOMA UNIFLORUM (Lam.) Verdc. PROTEINS

Field: Agricultural and Biological Sciences (Life Sciences)

Horse gram and moth bean seeds contained 23.6% and 21.9% protein (N x 6.25), respectively. Both the legumes are rich sources of iron. The iron contents in horse gram and moth beans were 11.0 and 9.6 mg/100 g, respectively. NaCl at 10% (w/v) and Na2CO3 at 0.5% (w/v) were found to be effective in extracting 89% and 80% of moth bean and horse gram proteins from defatted flour The minimum solubility of horse gram proteins from defatted flour was at pH 4.0 whereas proteins from moth bean exhibited minimum solubility at pH 4.5. The water and oil absorption, and foaming capacities in case of horse gram and moth bean flours were 2.0 g/g and 2.2 g/g, 23.0% and 2.0 g/g, 1.6 g/g, 27.6%, respectively.
Feature importance analysis for patient management decisions.

Field: Health Professions (Health Sciences)

The objective of this paper is to understand what characteristics and features of clinical data influence physician's decision about ordering laboratory tests or prescribing medications the most. We conduct our analysis on data and decisions extracted from electronic health records of 4486 post-surgical cardiac patients. The summary statistics for 335 different lab order decisions and 407 medication decisions are reported. We show that in many cases, physician's lab-order and medication decisions are predicted well by simple patterns such as last value of a single test result, time since a certain lab test was ordered or time since certain procedure was executed.
DAO2: Overcoming Overall Storage Overflow in Intermittently Connected Sensor Networks

Field: Computer Science (Physical Sciences)

Many emerging sensor network applications operate in challenging environments wherein sensor nodes do not always have connected paths to the base station. Data generated from such intermittently connected sensor networks therefore must be stored inside the network for some unpredictable period of time before uploading opportunities become available. Consequently, sensory data could overflow limited storage capacity available in the entire network, making discarding valuable data inevitable. To overcome such overall storage overflow in intermittently connected sensor networks, we propose and study a new algorithmic problem called data aggregation for overall storage overflow (DA0 2 ). Utilizing spatial data correlation that commonly exists among sensory data, DAO 2 employs data aggregation techniques to reduce the overflow data size while minimizing the total energy consumption. To solve DAO 2 , we uncover a new graph theoretic problem called multiple traveling salesman walks (MTSW), and show that with proper graph transformation, the DAO 2 is equivalent to the MTSW. We prove that MTSW is NP-hard and design a (2-1.)-approximation q algorithm, where q is the number of nodes to visit (i.e., the number of sensor nodes that aggregate their overflow data). The approximation algorithm is based on a novel routing structure called minimum q-edge forest that accurately captures information needed for energy-efficient data aggregation. We further put forward a heuristic algorithm and empirically show that it constantly outperforms the approximation algorithm by 15% -30% in energy consumption. Finally, we propose a distributed data aggregation algorithm that can achieve the same approximation ratio as the centralized algorithm under some condition, while incurring comparable energy consumption.
Impact of Variable Potassium on Metabolism, Oil, and Seed Quality of Groundnut

Field: Agricultural and Biological Sciences (Life Sciences)

To study the impact of variable potassium (K) on biomass, economic yield, and role of K in groundnut (Arachis hypogeae L.) metabolism, plants were grown in refined sand at different levels of K, ranging from 0.5 to 16 mM. The concentration of K increased with increase in supply in all parts of groundnut. Both low (<4 mM) and excess (>4 mM) K increased the activity of peroxidase, ATPase, and acid phosphatase and decreased the concentration of chlorophyll in leaves significantly. Low (<4 mM) and excess (>4 mM) concentrations of K inhibited pod and kernel (seed) formation in groundnut. Potassium stress (both low and excess) deteriorated the quality of groundnut seed by decreasing the concentrations of starch, protein, and oil and increasing that of sugars in seeds. The activities of certain enzymes also altered in K stress in leaves and seeds of groundnut.
Human Rights in Russia and Eastern Europe:Essays in Honor of Ger P. Van den Berg

Field: Social Sciences (Social Sciences)

List of Contributors Preface, F. Feldbrugge, W.B. Simons Capital Punishment in Russia, D. Barry Treatment of Anti-Constitutional Parties in Eastern Europe, G. Brunner Contracts and Constitutional Courts: The Experience of Russia, R.I. Dragneva, W.B. Simons Rights in Russian Legal History, F. Feldbrugge Constitutional Principles of Bona Fides and Impermissibility of the Abuse of Subjective Rights, G.A. Gadzhiev Extradition of Political Offenders Between Russia and Georgia, G. Ginsburgs How Right Are Economic and Social Rights? The Interaction Between Law and Economics in Human Rights, J. de Kort European Spaces: The Eastern Schengen Border and the Societies In-Between, J. Lowenhardt Property Rights as Human Rights: A Post-Communist Paradigm?, K. Malfliet Constitutional Right to a Favorable Environment and the New Law on the Protection of the Environment: Problems of Environmental Review, H. Oda On the Inequality of the Vote in the Russian Federation's State Duma Elections, H. Oversloot Planned Politics: The Russian Law on Political Parties, R. Verheul Index