jimnoneill/paper-to-field-training huggingface dataset:
Rapid traffic information dissemination using named data

Field: Computer Science (Physical Sciences)

This paper applies the Named Data Networking (NDN) concept to vehicle-to-vehicle (V2V) communications. Specifically, we develop a simple traffic information dissemination application based on the data naming design from our previous work and evaluate its performance through simulations. Our simulation results show that data names can greatly facilitate the forwarding process for Interest and data packets. With adequate vehicle density, data can propagate over long distances robustly at tens of kilometers per second, and a requester can retrieve the desired traffic information 10km away in a matter of seconds.
Ileal and colonic fatty acid profiles in patients with active Crohn's disease.

Field: Medicine (Health Sciences)

In patients with active Crohn's disease and in a control group the fatty acid profiles in the whole lipid fraction of ileal and colonic mucosal biopsy specimens were determined by capillary gas chromatography. The biopsy specimens in Crohn's disease patients were taken from the inflamed terminal ileum as well as from the inflamed and macroscopically normal colon. Compared with controls the fatty acid distribution in the inflamed ileal mucosa was significantly characterised by (a) a decrease of 18:2 n6 and 18:3 n3 accompanied by a substantial increase of the highly polyunsaturated fatty acids 20:4 n6, 22:4 n6, and 22:6 n3 and (b) a higher unsaturation index of total fatty acids compared with controls. These changes were similar in the inflamed colon. Additionally, both the inflamed and the macroscopically normal colonic mucosa showed an increase of saturated (18:0) and a decrease of monounsaturated fatty acids (18:1 n9). Fatty acid profiles of ileum and colon showed side variations in controls, but not in the Crohn's disease group. These data suggest that in Crohn's disease changes in the distribution of polyunsaturated fatty acids seem to be the general feature of inflamed mucosa in small and large intestine. Results further suggest that colonic fatty acid metabolism in Crohn's disease is altered by degrees, showing changes in saturated and monounsaturated fatty acids as an additional, primary event.
SEMBLANCE OF ELASTIC TISSUE TO MYCELIUM IN POTASSIUM HYDROXIDE PREPARATIONS

Field: Medicine (Health Sciences)

The novice in the field of medical mycology may be readily deceived by potassium hydroxide preparations of shavings of skin which extend down into the corium. Such specimens contain elastic tissue fibers which withstand digestion by potassium hydroxide and heat. The usual types of specimens examined in dermatologic practice, such as scales, scrapings and peelings of epidermis alone, naturally do not contain elastic tissue. Under low power, high dry or oil immersion magnification, the elastic tissue fibers appear to be a dense mycelium of fine, nonseptate, intertwining and branching hyphae. Although elastic tissue fibers are known to vary in thickness from a fraction of a micron to as much as 11 microns in diameter, they appear deceptively uniform in potassium hydroxide wet mounts. The fluorescence of the elastic tissue fibers under ultraviolet radiation may serve further to confuse the observer. Nothing resembling spores
Noordhoff Craniofacial Foundation—Online Operative Syllabus and Video Review

Field: Health Professions (Health Sciences)

From the Department of Plastic & Reconstructive Surgery, Hospital Geral Santa Casa da Misericordia do Rio de Janeiro, Rio de Janeiro, Brazil. Received July 13, 2017, and accepted for publication, after revision August 23, 2017. Conflicts of interest: None declared. Reprints: Lee Seng Khoo, MD, Department of Plastic & Reconstructive Surgery, Hospital Geral Santa Casa da Misericordia do Rio de Janeiro, R. Santa Luzia, 206 - Castelo, Rio de Janeiro - RJ, 20020-022, Brazil. E-mail: [email protected].
EVALUATION OF FAMILY IMPACT OF CHILDREN WITH CEREBRAL PALSY AND FAMILY CAREGIVER'S QUALITY OF LIFE, SLEEP QUALITY AND INDIVIDUAL PHYSICAL EDUCATION SATISFACTION: A MIXED STUDY

Field: Health Professions (Health Sciences)

Purpose: Cerebral Palsy (CP) is a disease that has significant effects on both the child and the family. The objective of this study is to examine the influence of the family, quality of life, sleep quality and individual physical education (IPE) of family caregivers of children with CP. In addition, it is planned to detail the factors affecting their satisfaction through semi-structured individual interviews. Methods: Family caregivers of 55 children diagnosed with CP between the ages of 1 and 15 were included in the study. Demographic information with “Demographic Information Survey”, the functional status of the child's with “Gross Motor Function Classification System (GMFCS)” the impact of the child on the family with “Impact on Family Scale (IoFS)”, caregiver's quality of life with “World Health Organization Quality of Life Scale - Short Form (WHOQOL-BREF) ”, caregiver's sleep quality was evaluated with “ Pittsburgh Sleep Quality Index (PSQI)” and the satisfaction with IPE was questioned with the “Pediatric Quality of Life Healthcare Parental Satisfaction Scale (PedsQL)”. Qualitative data were obtained through semi-structured individual interviews. Results: In our study, GMFCS level was negatively correlated with WHOQOL-BREF (p=0.028) and positively correlated with PSQI (p=0.002). In addition, the IoFS scale correlated negatively (p=0.000) with WHOQoL-BREF and positively (p=0.016) with PSQI. Conclusions: The findings of this study indicate that the physical dependence of the child has a negative impact on the quality of life and sleep quality of caregivers, and that the number of siblings affects parents' satisfaction with the treatment. It is recommended that further information be obtained regarding parents' perceptions of the disease and their individual physical education needs, as a result of semi-structured individual interviews.
Altered spinophilin interactions in the pancreas of a leptin receptor mutant ( db/db ) model of obesity

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Spinophilin is a multi‐domain scaffolding protein known to bind with multiple neuronal proteins, such as F‐actin and protein phosphatase 1 (PP1). Spinophilin modulation of glucose and M3 muscarinic receptor‐dependent insulin secretion has been recently evaluated. These studies established that spinophilin KO mice have decreased fat mass and increased lean mass. Yet spinophilin specific expression and the physiological and pathological functions of spinophilin within pancreatic beta cells have not been analyzed. Here we report that spinophilin is expressed in a rat INS‐1 pancreatic beta cell line and also human pancreatic islets. In isolated pancreatic mouse islets, spinophilin was detected in both pancreatic beta cells and non‐beta cell populations. Using proteomics‐based approaches we identified multiple putative spinophilin interacting proteins isolated from intact pancreas, including PP1, neurabin and myosin‐9. We are continuing to assess the interaction of spinophilin with these proteins in pancreata from mice that have a mutation in the leptin receptor ( db/db), a well‐characterized mouse model of type 2 diabetes and obesity. We have found that the associations of PP1 and neurabin with spinophilin were decreased in db/db mice as early as 6 weeks. The association of myosin‐9 with spinophilin was substantially increased in this same population. We are currently working with a transgenic mouse population that expresses a tagged form of human spinophilin in pancreatic beta cells to evaluate if changes in the spinophilin interactions are occurring within the pancreatic beta cells. Ultimately, Our data demonstrate that spinophilin is expressed in pancreatic beta cells and that spinophilin protein interactions in the pancreas are modulated under pathological conditions such as obesity. Future studies will examine how these changes in the spinophilin interactome may contribute to pathological sequelae associated with obesity and diabetes. Support or Funding Information Support and funding provided by NIH ‐ K01NS073700, R21DA041876 and by Indiana University School of Medicine Center for Diabetes and Metabolic Diseases Pilot and Feasibility Program and by IUPUI Department of Biology.
S9.4e Molecular epidemiology of Microsporum canis infection in Japan

Field: Immunology and Microbiology (Life Sciences)

Abstract S9.4 Free oral presentations (late breaking), September 23, 2022, 4:45 PM - 6:15 PM Objectives From a series of epidemiological surveys by the Japanese Society for Medical Mycology, it is estimated that the number of Microsporum canis (M. canis) infections in Japan has increased in recent years. The purpose of this study was to observe this trend by multilocus microsatellite (MLMT) analysis, a sensitive molecular marker. Methods DNA was extracted from 103 strains of M. canis isolated between 2017 and 2022 from Japanese patients and pet animals. Using the DNA, PCR targeting six individual microsatellites was performed. The size of each of these amplicons was measured by capillary electrophoresis, and their genotypes were determined from the combinations of their sizes. Results A total of 27 genotypes were detected among the 103 strains. Among the 27, 15 had been reported in studies of strains isolated before 2017, whereas 12 were newly determined in the present study. The genotype most frequently detected in the present study was genotype A, being present in 28 of the 103 strains. By geographical region, genotype A was found in strains distributed over a wide area of Japan. Genotype A strains have been isolated from cats purchased at pet shops and/or owners of these pet animals. The highest incidence of genotype in a study of strains isolated in 2010-2014 was also genotype A. Therefore, a large number of M. canis infections originating from pet shops and animal breeders are likely prevalent in Japan today. Furthermore, a relatively large number of strains were identified as genotypes rare or absent in 2010-2014. Conclusions The increase in the number of M. canis infections in recent years may be the increase in infections of different genotypes, in addition to the base of constant infections by genotype A, by the present MLMT analysis.
The Mining and Resource Contractors Safety Training Association (MARCSTA) and the efficacy of a generic occupational health and safety induction system when used across an industry

Field: Health Professions (Health Sciences)

The Mining and Resource Contractors Safety Training Association (MARCSTA) developed a generic occupational health and safety (OHS) induction program that was first used by the metalliferous mining industry in Western Australia (WA) in 1996. Subsequently the mining industry in Tasmania has adopted the course and it has been on offer in that state since 2000. More than 150 000 trainees have attended the MARCSTA course to date (Gilroy, 2006). An empirical research study analysing data collected from a randomly selected group of 1 600 trainees who attended the course was conducted over a twelve month period. Furthermore historical OHS accident and injury data were analysed for the period prior to and after the introduction of the MARCSTA program.
Physical 1/f noise and phase noise in piezoelectrics, MEMS resonators and sensors

Field: Physics and Astronomy (Physical Sciences)

The physical quantum theory of 1/f noise describes the infrared-divergent conventional Q 1/f fluctuations of quantum mechanical cross sections and process rates by simple, universal, formulas. We give the resulting formulas for this 1/f noise and phase noise in piezoelectrics, MEMS resonators and sensors, STMs, their piezo-control loop, and currents in ferroelectrics.
Heterogeneity of cellulase complexes fromTrichoderma reesei:A preparative isoelectric focusing study of some extracellular hydrolases

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Homogeneity of extracellular proteins of Trichoderma reesei found after isoelectric focusing (IEF) has been shown to reflect purity of a (multi)enzyme complex rather than purity of one enzyme isolated. The intention of the present study was to demonstrate to what extent distribution of (multi)enzyme complexes reflects a general concept of extracellular hydrolases in the culture fluid of T. reesei. The complete culture fluid studied by preparative IEF on the distribution of cellulases, β-glucosidase, xylanase and xylosidase confirms this view. (Macro)heterogeneity found after IEF is discussed on the basis of different charges of complexes.
Yield Trends during Take‐all Decline in Spring Barley and Wheat Grown Continuously1

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract The effects of take‐all, nitrogen and cropping sequence on grain yield were compared for spring barley and spring wheat grown in extended monoculture. Initial crops showed least take‐all and maximum yields. Yields fell to a minimum more rapidly in wheat than in barley while the take‐all intensity increased to a maximum; take‐all decline occurred and yields improved from the 4th and 5th years respectively. Without nitrogen, yields were at their lowest level; application of nitrogen increased yields considerably with responses in proportion to the rate applied. At optimum rates, yield losses were 33% for wheat and 11% for barley with maximum disease intensity but only 9% and 3% respectively with take‐all decline. Potential maximum yields in the absence of take‐all were calculated to be greater with barley than with wheat.
Convenient Synthesis of N-Hydroxysuccinimide Esters from Carboxylic Acids Using Triphosgene

Field: Chemistry (Physical Sciences)

Abstract A simple and convenient method for the synthesis of N-hydroxysuccinimide ester is developed using triphosgene as an acid activator. Several aromatic and aliphatic N-hydroxysuccinimide esters are prepared from their corresponding carboxylic acids at room temperature in good yields in a rapid process using triphosgene. Some of the major advantages are mild conditions, good yields, and easy operation.
The variable clinicopathological categories and role of human papillomavirus in cervical adenocarcinoma: A hospital based nation‐wide multi‐center retrospective study across China

Field: Medicine (Health Sciences)

We investigated HPV in adenocarcinoma presenting and managed as cervical adenocarcinoma (CADC) at seven major representative regional cancer centres across China. From 1,051 CADC cases diagnosed locally in 2005–2010, 881 had available paraffin embedded tissue. Initial review excluded 154 cases as other diagnoses or inappropriate specimens. In 718 eligible cases consensus panel pathology diagnosis was made using an algorithm incorporating p16 and progesterone receptor immunohistochemistry (IHC). Classification of cervical adenocarcinoma categories was subject to substantial pathological disagreement. High‐risk human papillomaviruses (HR‐HPV) DNA was studied by the sensitive SPF10 PCR‐DEIA‐LiPA25 version 1 for L1 genes and type‐specific HR‐HPV E6/7 gene PCR's. HR‐HPV prevalence in whole tissue samples in eligible tested CADC was 74.5%: 100.0% in neuro‐endocrine carcinoma (NEC), 82.2% in classical cervical adenocarcinoma (ADC‐CX), 40.0% in adenocarcinoma‐not otherwise specified (ADC‐NOS) and 33.3% in endometrioid adenocarcinoma (ADC‐ENDO). Higher mean age at diagnosis correlated with histological categories showing low HPV prevalence (Linear regression: β = −13.794, p < 0.001). HPV‐16 and 18 were associated with early development of CADC and a lower mean age correlated with carcinogenic risk of associated HPV ( β = −0.1829, p < 0.001). HPV‐16 or HPV‐18 was found in 88.2% of all HPV positive cases including multiple‐infections. HPV‐18 was the commonest HPV type in NEC (58.3%), ASC (40.2%) and ADC‐CX (40.9%). The proportion of HPV‐unrelated CADC and in different final histological categories varied geographically and by age. Although HPV negativity was predominantly associated with special categories of CADC, some HPV‐negative usual adenocarcinomas indistinguishable by adjudicated microscopic diagnosis from ADC‐CX were found and varied in frequency across China.
PDA comments: SUPAC-IR, ICH Q1C, FDA draft guideline. Parenteral Drug Association.

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Following are comments prepared by PDA on three draft regulatory documents all relating to stability for post-approval changes, new dosage forms and related issues. The comments on SUPAC-IR and ICH Q1C were submitted to FDA on February 10, 1995. The comments on the December 12, 1994 draft guideline were submitted on March 10, 1995. The documents have different sources and content, however, there is some overlap between the three. Readers may wish to peruse the table attached to the March 10, 1995 PDA comments for a graphic analysis of the contents of the three documents. Readers are cautioned that these comments are based on draft proposals by FDA and/or the International Conference on Harmonization. More recent drafts may be available. Copies of all three documents are available from PDA (SUPAC-IR: Document #FDA 79; ICH Q1C: #FDA 93; December 12, 1994 guideline: #FDA 77). See the PDA Letter or contact the PDA staff for additional information. Further clarifying comments can be found in the January, March and April 1995 issues of the PDA Letter. Staff contact is James Lyda. PDA expresses thanks to the working group which drafted the comments on very short notice: Raymond Shaw, Jr. Ph.D., Merck (now of Wyeth-Ayerst) (Chair); Robert Barraza, Burroughs Wellcome; Fred Gustafson, Abbott; Paulette Kosmoski, and Russel Madsen and James Lyda, PDA.
INSECT HERBIVORY ON FERNS FROM A MODERN MARSH LOWLAND LOCALITY, SOUTHERN BRAZIL: IMPLICATIONS FOR INTERPRETING FOSSIL PLANT–INSECT INTERACTIONS

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract Ferns are a model plant group for comparing insect herbivory between modern and deep time assemblages. We assessed fern–arthropod interactions in a modern marsh to reveal the taphonomic, morphological, and ecological implications of insect herbivory on fossil plant assemblages. Six functional feeding groups—hole feeding, margin feeding, surface feeding, piercing and sucking, galling, and pathogens—are present in eight fern species. We identified a total of 23 distinct damage types (DTs) on ferns, comprising 16 insect-mediated DTs, two of which are newly described in this study, and seven pathogen DTs, including one new addition. Among these, we present six arthropod-induced DTs that were previously undocumented in ferns. Furthermore, we report five DTs with fossil analogs. External foliage feeding, consisting of hole feeding, margin feeding, and surface feeding functional feeding groups, is the principal factor for DT richness on ferns in this lowland locality. We found products of arthropods behavior on ferns, such as instar molts and dead bodies and the byproducts from reproductive processes, which are unlikely to preserve in the fossil record. The taphonomic implications of these arthropod behavioral products are inferred by considering the substances that attach these structures to leaf tissues, potentially enhancing their preservation potential in the fossil record. Relatively mesic conditions support ferns in the lowland locality, resulting in a greater richness of insect herbivory compared to ferns in cooler xeric habitats from a previously surveyed upland locality.
The Geology of The basement Formation at Mufulira Mine

Field: Earth and Planetary Sciences (Physical Sciences)

The copper mineralisation at Mufulira mine is largely influenced by the structural geology of the underlying basement formation. i was investigating the possible association between the basement formation and the distribution of mineralisation in the overlying units. this was largely done through mapping, loggin of diamond core, assaying and petrographic analysis of the basement units and the overlying ore bearing units.
The EU and Weapons of Mass Destruction

Field: Social Sciences (Social Sciences)

The policy domain of the proliferation of nuclear weapons and of weapons of mass destruction is a complex one, that Europe has engaged with in different ways. North Korea and Iran are both projected as problematic and irrational; Pakistan and in particular India have not, and their nuclear developments have been placed in a different frame. The EU is marginalised from some security governance discourses â for example, the Six Nation Talks on North Korea â but is deeply concerned with others; notably the debate over Iran. But the way that Europe talks about nuclear proliferation also says much about the way Europe sees itself and its role in the world, and also has to be set in the context of its own complex formation, with nuclear weapons states, and others strongly committed to speedily bring about a world without nuclear weapons.
“Physical Activity Is Not the Answer to Everything, but It Is to a Lot”: Stakeholders’ Perceived Determinants of Implementing Physical Activity Interventions for Older Adults: An Interview Study Using the Consolidated Framework for Implementation Res

Field: Health Professions (Health Sciences)

Although many physical activity (PA) interventions for older adults have proven ef-fective in controlled research settings, optimal implementation in real life remains challenging. This study identifies determinants perceived by stakeholders when im-plementing community-based PA interventions for older adults. We interviewed 31 stakeholders guided by the Consolidated Framework for Implementation Research (CFIR). Results showed that stakeholders are very specific about the role they can play in implementation making collaboration between stakeholders crucial. Barriers and motivators were identified in the CFIR intervention characteristics domain (relative advantage, complexity and costs, evidence quality and strength, and adaptability and trialability), in the outer setting domain (cosmopolitism, patient needs, and external policy and incentives), in the inner setting domain (implementation climate, relative priority, compatibility and organizational incentives and rewards) and in the individ-ual characteristics domain (knowledge and beliefs, and other personal attributes). An overarching theme was the stakeholders&#039; emphasis on aiming for broad health goals in interventions, as they perceive PA as a means to reach these goals rather than an end in itself. Another overarching theme requiring attention in future implementation ef-forts is the need to tailor implementation efforts to the specific needs of older adults as the end users of the intervention.