jimnoneill/paper-to-field-training huggingface dataset:
An Algebra for Queueing Networks with Time-Varying Service and Its Application to the Analysis of Integrated Service Networks

Field: Decision Sciences (Social Sciences)

We introduce a network model that allows us to capture the time-varying service delivered to a traffic stream due to the presence of random perturbations (e.g., cross-traffic in a communication network). We first present the model for a single network element and then describe how such elements may be interconnected using the operations of fork and join. Such networks may be seen as a generalization of stochastic event graphs and of the class of fork-join networks. The departure processes in such a network satisfy a system of equations along with the exogenous arrival processes and the service processes of the various network elements. This system can be seen as a general time-varying linear system in the (min, plus) semi-field. We obtain an explicit representation of the departure process in terms of the exogenous arrival processes and the service processes. Sufficient conditions are derived for this system to have a unique solution. We also study liveness and absence of explosion in this class of networks. Under appropriate stationarity and ergodicity assumptions, we establish stability theorems for such networks. To this end we first obtain a rate result for the departure process in terms of the rates of the exogenous arrival process and the throughput of a saturated system. We then use this result to show that in a network with a single exogenous arrival, all queue lengths are finite with probability one if the arrival rate is less than the throughput of the saturated system, and to give a representation of the queue-length process. This class of networks allows for a detailed description of controlled sessions in integrated service networks. We also show that it contains several earlier discrete event models of the literature pertaining to stochastic Petri nets, service curves, and fork-join networks and show how the present model unifies them in a single algebraic structure. This structure is that of a semi-ring of functions of two real variables, where the addition is the pointwise minimum and the multiplication a generalization of inf-convolution.
Risk factors for adverse pregnancy outcomes in obstetric antiphospholipid syndrome

Field: Medicine (Health Sciences)

Abstract Background : Antiphospholipid syndrome (APS) causes adverse obstetric outcomes in the affected patients. Our study aimed to investigate the risk factors for adverse pregnancy outcomes (APOs) in women with APS. Methods : This retrospective study included 143 pregnant women with APS admitted to Peking University People’s Hospital. Based on the presence of APOs, pregnant women were divided into the adverse outcomes group (n=49) and the non-adverse outcomes group (n=94). Clinical data were extracted from medical records. Univariate and multivariate logistic regression analyses were used to identify the risk factors associated with APOs. Results : We found that the low platelet count (≤50×10 9 /L), hypertension during pregnancy, and single-positivity of antiphospholipid antibody (aPLs) were the risk factors of APOs after adjusting age, the number of prior spontaneous miscarriages, weight change during pregnancy, gestational diabetes, thrombosis, oligohydramnios, and aPLs status (model I). Of importance, hypertension during pregnancy and single-positivity of aPLs remained the risk factors for adverse outcomes, but the low platelet count (≤50×10 9 /L) was no longer a risk factor after adding the adjustments of the time of diagnosis and treatment during pregnancy (model II). And the number of platelets increased after delivery under the treatment (87.53±49.81 vs. 65.06±41.3 vs. 52.75±20.70 vs. 110.19±55.30; p <0.05). Therefore, treatment could effectively decrease the risk of adverse outcomes in pregnant APS patients with thrombocytopenia. Conclusion : APS increases the risk of adverse outcomes during pregnancy. Thrombocytopenia, hypertension during pregnancy, and single-positivity of aPLs were the risk factors of APOs in women with APS. Treatment can significantly reduce the risk of adverse outcomes by upregulating platelet count during pregnancy in APS patients with thrombocytopenia.
Rapid Construction of Polycyclic Skeletons via Brønsted-Base-Catalyzed Annulations of Ethylidene 1,3-Indenediones and Vinyl 1,2-Diketones

Field: Chemistry (Physical Sciences)

Brønsted-base-catalyzed diversified annulations between ethylidene 1,3-indenediones and vinyl 1,2-diketones have been achieved, delivering three types of products containing oxabicyclo[3.2.1]octane, spiro[4.5]decane, and branched triquinane skeletons, respectively, which widely exist in natural products and bioactive substances. Two unprecedented reaction modes have been disclosed, and the reactions could be readily scaled up. The protocol shows the potential of 1,2-diketone-mediated reactions in the rapid construction of complicated polycyclic scaffolds.
Event-Triggered Dynamic Output Feedback Control for Networked T-S Fuzzy Systems With Asynchronous Premise Variables

Field: Computer Science (Physical Sciences)

This paper investigates the problem of event-triggered dynamic output feedback control for networked Takagi-Sugeno (T-S) fuzzy systems with asynchronous premise variables. Our attention is focused on the design of an event-triggered fuzzy dynamic output feedback controller that guarantees that the closed-loop system is asymptotically stable. First, with consideration of the limited bandwidth and restricted network resource, an event-triggered communication scheme is proposed to save the limited network resource. Second, different from the existing results in the literature, a fuzzy dynamic output feedback controller with asynchronous premise variables is constructed such that the premise membership functions are not necessarily the same as the networked T-S fuzzy systems. Then, by using the Wirtinger inequality and some slack matrices, a less conservative stability and stabilization conditions for the existence of fuzzy dynamic output feedback controller are derived in the form of linear matrix inequalities, which can be solved by the standard MATLAB toolbox. Finally, an example is given to demonstrate the effectiveness of the designed event-triggered fuzzy dynamic output feedback controller.
Triticum sp., GB20_SSD_TRI_23869_8861

Field: Agricultural and Biological Sciences (Life Sciences)

PGRFA research material of IPK Gatersleben SSD line selection Selected from: 10.25642/IPK/GBIS/256075 Taxon: Triticum sp. Accession number: GB20_SSD_TRI_23869_8861 Conserved by: DEU146 Acquisition: 20170821 Origin country: FRA Biological status: 400
Empowering Sustainability: Floating Solar Photovoltaic Systems in Agriculture for Reduced Costs Carbon Emissions and Evaporation

Field: Environmental Science (Physical Sciences)

Abstract This study assesses the impact of implementing a floating solar photovoltaic system (FSPV) on the Turgutlu irrigation pond in Sakarya, Turkey, aiming to reduce energy expenses in agricultural irrigation and promote sustainability in farming. Two scenarios are developed to evaluate the FSPV, focusing on CO 2 emissions mitigation, energy generation potential, evaporation reduction, conservation of terrestrial land, effects on agricultural production, decreased reliance on fossil fuels, and associated costs and return on investment (ROI). In the first scenario, the FSPV is expected to generate 7168 MWh of energy, preventing the emission of 4520 tons of carbon, and reducing annual evaporation by 6686 m 3 . In the second scenario, the FSPV's energy output is estimated at 99 MWh, preventing 64.2 tons of carbon emissions, and reducing annual evaporation by 94.4 m 3 . These findings provide valuable insights at the regional level, presenting a compelling case study for potential replication in other irrigated agricultural regions.
Crafting innovation: Discrete timber pavilions and fabrication-driven approaches

Field: Engineering (Physical Sciences)

In regions with limited access to CAD/CAM machines like Latin America, academic experiences have adapted digital tools to local capabilities, aiming to enhance project creativity through digital technology. This article examines the use of timber as a material, addressing the technical, spatial, and cultural aspects related to its use, while intertwining the educational narrative of learning through doing and adapting. The structures designed in this research are based on three key parameters: timber as the main material, framing as a discrete design system and side-by-side joints as a vital component of the traditional fabrication process. Through the integration of digital and traditional techniques, the aim is to adapt methods frequently used in digital design and manufacturing processes. This study emphasizes that merging digital tools with traditional construction knowledge can lead to innovative solutions, especially in areas with limited digital resources, showing that digital fabrication can broaden and enrich traditional building methods beyond just being a numerical alternative.
Review of CoreTrustSeal Applicability to non-Preservation (Trustworthy) Data Services

Field: Social Sciences (Social Sciences)

This brief working paper provides a tabular overview of the CoreTrustSeal Requirements and how they apply to non-preservation data and metadata services.
Some concluding remarks provide a first outline of the functional components of trustworthy data services based on this initial analysis. With the exceptions of “Preservation Plan” and “ReUse” our assessment is that all of the CoreTrustSeal Requirements are applicable to any (meta)data service that seeks to demonstrate trustworthiness to its depositors, funders, users and peers.
This is a first step in an internal planning and analysis process by the UK Data Service. It is shared in the interests of transparency and to provide a reference point for some engagement with peers on this topic.
Difference in Perception of Onset of Old Age in Traditional (Hadza) and Modern (Polish) Societies

Field: Social Sciences (Social Sciences)

Despite relatively clear physiological indicators of old age, little is known about cross-cultural differences in psychological perceptions of the transition to old age. Although recent studies suggest consistency between modern countries, the subjective perception of old age onset in traditional societies remains poorly explored. Therefore, we compared the perception of timing of old age between a traditional tribe of hunter-gatherers (the Hadza) and a Polish sample representing a modern, industrialized population. The results indicate that the Hadza perceive old age onset as being significantly earlier than do the Poles. Furthermore, we found between-gender differences in the Polish sample: men set a lower threshold of old age onset than women. The Hadza showed no between-gender difference. Although the samples were matched for age, a larger proportion of Hadza considered themselves old. We discuss these findings from cultural and demographical perspectives.
Exact Learning of Multivalued Dependencies

Field: Computer Science (Physical Sciences)

The transformation of a relational database schema into the fourth normal form, which minimizes data redundancy, relies on the correct identification of multivalued dependencies. In this work, we study the learnability of multivalued dependency formulas (MVDF), which correspond to the logical theory behind multivalued dependencies. As we explain, MVDF lies between propositional Horn and 2-Quasi-Horn. We prove that MVDF is polynomially learnable in Angluin et al.’s exact learning model with membership and equivalence queries, provided that counterexamples and membership queries are formulated as 2-Quasi- Horn clauses. As a consequence, we obtain that the subclass of 2-Quasi-Horn theories which are equivalent to MVDF is polynomially learnable.
Ultrasonographic aspects of the gallbladder mucocele in 30 dogs: retrospective study

Field: Veterinary (Health Sciences)

Gallbladder mucocele is characterized by hyperplasia of the gallbladder epithelium, increased mucus production, accumulation, and densification of the bile content, which can lead to biliary obstruction, necrosis, and rupture of the gallbladder wall. Its finding may be accidental or related to symptoms. A retrospective study (2016-2019) was carried out based on abdominal ultrasound examinations in dogs, correlating aspects of the gallbladder and biliary system in the mucocele with existing comorbidities. Thirty dogs diagnosed with biliary mucocele were evaluated, of which 46.66% had the disease at an early stage, and 53.33% showed a more advanced stage. Of these, 66.66% were related to endocrinopathies and hyperadrenocorticism. Signs of extrahepatic bile duct obstruction and biliary peritonitis were observed in two animals. Due to their potential risk of complications, follow-up ultrasound assessments are indicated in cases that opt for clinical treatment, not excluding the need for surgical intervention.
The analysis and recognition of real-world textures in three dimensions

Field: Computer Science (Physical Sciences)

The observed image texture for a rough surface has a complex dependence on the illumination and viewing angles due to effects such as foreshortening, local shading, interreflections, and the shadowing and occlusion of surface elements. We introduce the dimensionality surface as a representation for the visual complexity of a material sample. The dimensionality surface defines the number of basis textures that are required to represent the observed textures for a sample as a function of ranges of illumination and viewing angles. Basis textures are represented using multiband correlation functions that consider both within and between color band correlations. We examine properties of the dimensionality surface for real materials using the Columbia Utrecht Reflectance and Texture (CUReT) database. The analysis shows that the dependence of the dimensionality surface on ranges of illumination and viewing angles is approximately linear with a slope that depends on the complexity of the sample. We extend the analysis to consider the problem of recognizing rough surfaces in color images obtained under unknown illumination and viewing geometry. We show, using a set of 12,505 images from 61 material samples, that the information captured by the multiband correlation model allows surfaces to be recognized over a wide range of conditions. We also show that the use of color information provides significant advantages for three-dimensional texture recognition.
Fenofibrate Alleviates Insulin Resistance and Hepatic Steatosis via Modulation of let-7/ SERCA2b&nbsp;Axis

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Abstract

Background: Fenofibrate is a peroxisome proliferator-activated receptor alpha agonist, which is widely used in clinical practice to effectively ameliorates the development of NAFLD. However, the molecular mechanism remains largely unknown, the present study aimed to investigate the role and specific mechanism of fenofibrate on lipid metabolism disorders associated diseases.Methods: The male C57BL6/J mice were divided into 3 groups, the mice in control group (n=10) were fed with normal chow diet, and the mice in HFD-fed group (n =10) were fed with a high fat diet (HFD) for 14 weeks. For the fenofibrate +HFD-fed group (n =10), the mice fed HFD were orally gavaged with fenofibrate (40 mg/kg) daily for the last 4 weeks. Body weight and hip width were measured. Macrosteatosis and fat deposition in the liver were measured by H&E staining and Oil red O staining individually. The levels of serum and hepatic triglyceride were measured, and HOMA-IR, HOMA-ISI were analyzed. The levels of SCD-1, Bip, CHOP and SERCA2b were measured by western blotting. The expression of let-7 were analyzed by qPCR, and the complementarity between the 3′-UTR of SERCA2b gene and let-7 was measured by luciferase reporter assay.Results: Fenofibrate reduces hepatic steatosis and insulin resistance in HFD-fed mice. Fnofibrate alleviates endoplasmic reticulum stress (ER stress) of mice fed a high fat diet (HFD). Fenofibrate increases the levels of Sarco-endoplasmic reticulum Ca2+-ATPase 2b (SERCA2b) which serves as a regulator of ER stress. Further, the levels of let-7 microRNA is also regulated by fenofibrate, and let-7 directly targets 3’-UTR of SERCA2b. Conclusion: The present data suggests that fenofibrate alleviates ER stress through the let-7/SERCA2b axis to protect against excessive lipid accumulation in the liver of Non-alcoholic fatty liver disease (NAFLD) mice.
Organic Cation Transporter 2 Overexpression May Confer an Increased Risk of Gentamicin-Induced Nephrotoxicity

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

ABSTRACT Nephrotoxicity is a relevant limitation of gentamicin, and obese patients have an increased risk for gentamicin-induced kidney injury. This damage is thought to depend on the accumulation of the drug in the renal cortex. Obese rats showed substantially higher levels of gentamicin in the kidney than did lean animals. This study characterized the role of organic cation transporters (OCTs) in gentamicin transport and elucidated their possible contribution in the increased renal accumulation of gentamicin in obesity. The mRNA and protein expression levels of the organic cation transporters Oct2 (Slc22a2) and Oct3 (Slc22a3) were increased in kidney samples from obese mice fed a high-fat diet. Similarly, OCT2 (∼2-fold) and OCT3 (∼3-fold) showed increased protein expression in the kidneys of obese patients compared with those of nonobese individuals. Using HEK293 cells overexpressing the different OCTs, human OCT2 was found to transport [ 3 H]gentamicin with unique sigmoidal kinetics typical of homotropic positive cooperativity (autoactivation). In mouse primary proximal tubular cells, [ 3 H]gentamicin uptake was reduced by approximately 40% when the cells were coincubated with the OCT2 substrate metformin. The basolateral localization of OCT2 suggests that gentamicin can enter proximal tubular cells from the blood side, probably as part of a slow tubular secretion process that may influence intracellular drug concentrations and exposure time. Increased expression of OCT2 may explain the higher accumulation of gentamicin, thereby conferring an increased risk of renal toxicity in obese patients.
Synergistic Antimalarial Activity of Pyrimethamine and Sulfadoxine against Plasmodium falciparum In Vitro

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Two strains of Plasmodium falciparum were tested in vitro for sensitivity to the dihydrofolate reductase inhibitor pyrimethamine, the p-aminobenzoic acid (PABA) analogue sulfadoxine, and combinations of both drugs. One strain was sensitive and one resistant to pyrimethamine in vitro. Parasites cultured in medium containing neither folic acid nor PABA were inhibited by 10(-6) M sulfadoxine, a concentration well below that achievable after therapeutic dosage. Folic acid added to this medium at a physiological concentration of 0.01 mg/liter caused a 1,000-fold reduction in sulfadoxine activity; a 100-fold higher concentration of folic acid caused a 10-fold reduction in pyrimethamine activity. Sulfadoxine in a concentration of 10(-7) M was able to potentiate pyrimethamine activity in PABA-free medium with no added folic acid or with 0.01 mg folic acid/liter. These data indicate that P. falciparum can utilize exogenous folic acid, and suggest that sulfadoxine may potentiate pyrimethamine activity by simultaneous inhibition of dihydrofolate reductase.
Optimizing building material supplier selection through integrated interval-valued intuitionistic fuzzy multi-attribute decision making

Field: Decision Sciences (Social Sciences)

In engineering construction, the unavoidable issue is how to choose suitable suppliers. The quality of suppliers has a direct impact on the progress, quality, and cost of the project. The selection of suppliers for construction projects in water conservancy and hydropower engineering is directly related to the cost of construction enterprises, and large-scale construction projects have stricter requirements for cost control. The investment in engineering construction is very huge, so cost control ability is a very important assessment indicator for construction project construction, and the cost of materials is a significant part of the construction project cost. Therefore, the research on the selection and optimization of building material suppliers is a topic that cannot be ignored. The building material supplier selection is a multi-attribute decision making (MADM). In this paper, some calculating laws on IVIFSs, Hamacher sum, Hamacher product are introduced, and the induced interval-valued intuitionistic fuzzy Hamacher interactive ordered weighted averaging (IVIFHIOWA) operators (I-IVIFHIOWA) operator is proposed. Meanwhile, some ideal properties of I-IVIFHIOWA operator are studied. Then, the I-IVIFHIOWA operator is employed to cope with the MADM under IVIFSs. Finally, an example for building material supplier selection is employed to test the I-IVIFHIOWA operator.
Hematological damage and risk factors prediction in HIV-infected patients with secondary malignancies：A single-center study from China

Field: Medicine (Health Sciences)

Abstract

Purpose The incidence and mortality of secondary malignant tumors (MT) in people living with HIV(PLWH) are increasing. The purpose of this study is to analyze the characteristics of Complete Blood Count (CBC), bone marrow and immunity in PLWH with secondary MT, so as to provide data reference for diagnosis and risk factor assessment strategies of such patients.Methods We collected 297 patients who were diagnosed with PLWH and required bone marrow examination, including 101 cases of PLWH with secondary MT and 196 cases of PLWH without MT. The CBC, bone marrow and immune index of the two groups of patients were retrospectively analyzed.Results In terms of WBC, RBC, HGB, PLT, NEUT, the granulocyte ratio in bone marrow and CD4 cell counts, both were lower than those of pure PLWH. The independent risk factors of PLWH with secondary MT were HGB < 90g/L (RR = 1.581, 95%CI: 1.030–2.427, P = 0.036), the morphology of RBC in BM showed senescent nuclei and immature cytoplasm (RR = 1.489, 95%CI: 1.006–2.203, P = 0.046) and CD4 cell count < 100 cells/ul (RR = 2.307, 95%CI: 1.406–3.787, P = 0.001). HGB < 60g/L and RBC ratio of bone marrow < 0.2 were the independent risk factors associated with prognosis. The best hematologic predictor of PLWH with secondary MT was HGB (AUC = 0.707, 95%CI: 0.642–0.772, P < 0.001).Conclusion Severe anemia, the abnormal morphology of RBC in bone marrow, severe immune deficiency increase the risk of secondary MT in PLWH. Severe anemia and decreased RBC ratio in bone marrow are independent factors affecting the prognosis of PLWH with secondary MT.
The length scale effect between wall and closes field point on a single turbine blade simulation / Mohd Hafiz Mohd Noh ... [et al.]

Field: Engineering (Physical Sciences)

A numerical code has been developed based on experiment data, by using Finite Volume Method. Four different turbulence models (one equation model) have been tested; Spalart–Allmaras, Delay Eddy Simulation, Delay Detached Eddy Simulation and Improve Delayed Detached Eddy Simulation. The exit Reynolds number is 2.8  106 and the exit isentropic Mach number is 0.79. The code has been validated with isentropic Mach number around the blade, trailing edge pressure distribution, vortex shedding frequency at S/D=-0.62 and boundary layer profile at a distance equal to one. DDES has shown a good agreement qualitatively and quantitatively with the experiment as compared with others and at region -1
Marmaduke Carver

Field: Arts and Humanities (Social Sciences)

Marmaduke Carver Get access J. L. Hobbs J. L. Hobbs Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume 191, Issue 8, 19 October 1946, Page 173, https://doi.org/10.1093/nq/191.8.173a Published: 19 October 1946