jimnoneill/paper-to-field-training huggingface dataset:
[Relay levels of acoustic and tactile startle reflexes in the reticular formation of the cat].

Field: Neuroscience (Life Sciences)

Reticular mechanisms of startle reflexes evoked by acoustic and tactile stimulation were studied in cat anesthetized with chloralose. Marked similarity in changes of both reflexes following surgical lesions and reversible hydrocompression blockade of the medial brain stem reticular formation structures were found. The data obtained evidenced for similarity of reticular substrates of these nonnociceptive reflexes (the pontine reticular formation, especially nucleus reticularis, pontis caudalis) in contrast to nociceptive spino-bulbo-spinal startle reflexes relayed mainly over the bulbar reticular formation.
Biocide Combinations for Improved Microbiological Control

Field: Chemical Engineering (Physical Sciences)

Abstract The uncontrolled growth of microorganisms can cause severe problems in industrial water systems. The most common method of controlling microbial growth in industrial water systems has been through the use of biocides. While a wide variety of biocides are available to the water treatment industry, improved methods are required to address efficacy, economic, and environmental concerns. The non-oxidizing biocide tributyl tetradecyl phosphonium chloride has been shown to be effective against a broad range of microorganisms in a wide variety of industrial environments. We report here on the use of tributyl tetradecyl phosphonium chloride in combination with other commonly used industrial water treatment biocides. The combinations show improved performance compared to the individual biocides alone. The improved performance leads to increased cost performance, reduced system corrosion, and reduced environmental impact of the biocide treatment.
In vitro determination of the effect of indoleglycerol phosphate on the interaction of purified TrpI protein with its DNA-binding sites

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Expression of the trpBA gene pair of Pseudomonas aeruginosa is regulated by the endogenous level of indoleglycerol phosphate (InGP) and the trpI gene product. The TrpI protein binds to the -77 to -32 region of the trpBA promoter. This region is divisible into two sites: site I, which is protected by TrpI in the presence and absence of InGP; and site II, which is protected by TrpI only in the presence of InGP. Recently, the trpI gene was subcloned into an expression vector and the protein was overproduced in Escherichia coli. The TrpI protein was purified to 80 to 95% purity. The molecular weight of native TrpI protein is estimated to be 129,000 by gel exclusion chromatography, and therefore it is likely a tetramer composed of 31,000-dalton monomers. Gel retardation assays with the purified TrpI protein demonstrated that InGP increases the affinity of TrpI for sites I and II approximately 17- and 14-fold, respectively. Binding of TrpI to site I is site II independent. However, the protein has low intrinsic affinity for site II and its binding to site II is site I dependent. Therefore, binding of TrpI to site II probably requires its interaction with a second TrpI molecule at site I.
Cyberbots - fullmetal madness: (US) dragonkid vs(BR) GingaNoTarzan - 2021-03-02 21:04:08

Field: Computer Science (Physical Sciences)

(US) dragonkid vs (BR) GingaNoTarzan - 2021-03-02 21:04:08 Fightcade replay id: 1614719048632-1524 For more videos check out: https://fightcadevids.com
An 8.5mW 5GS/s 6b flash ADC with dynamic offset calibration in 32nm CMOS SOI

Field: Engineering (Physical Sciences)

This paper describes a 5GS/s 6bit flash ADC fabricated in a 32nm CMOS SOI. The randomness of process mismatch is exploited to compensate for dynamic offset errors of comparators that occur during high speed operation. Utilizing the proposed calibration, comparators are designed with near-minimum size transistors and built-in reference levels. The ADC achieves an SNDR of 30.9dB at Nyquist and consumes 8.5mW with an FoM of 59.4fJ/conv-step.
Upbringing in cities is associated with an increased risk of asthma in adulthood

Field: Medicine (Health Sciences)

Background: The prevalence of asthma has risen steeply in the last decades and several risk factors have been identified. Studies have suggested a protective effect of farm upbringing on the risk of asthma. Aim: To examine the association between living in cities compared to living in rural areas in the risk of self-reported physician-diagnosed (SR-PD) in adulthood. Methods: 12,449 twins, aged 40-80 years, from the Danish Twin Registry were recruited. The participants completed a questionnaire on upbringing, medical history, life style factors and a clinical examination. Individuals who at age 6 and 15 lived in cities (four largest cities and surburbs) were compared with individuals who lived in rural areas (small towns and villages). Sex, age, smoking, BMI, alcohol consumption, intake of fruits and vegetables, and physical activity were included as covariates. Results: 48% of the participants were males. The mean age was 58.4 years ±9.6; mean BMI was 26.6 kg/m2 ± 4.4. The prevalence of SR-PD asthma was 7.3%. A multiple logistic regression showed an increased risk of SR-PD asthma in individuals who lived in cities at both age 6 and 15, OR=1.28 (1.31-1.48), p=0.001. Sensitivity analyses showed that the risk was more increased in younger age groups; 50-60 years, OR=1.33 (1.02-1.74), p=0.04 and 40-50 years; 1.47 (1.12-1.91), p=0.005. Conclusions: In this large nationwide study we found that individuals living in cities during their childhood have a 28% increased risk of SR-PD asthma as adults. These results underline the importance of residency during childhood and subsequent risk of asthma.
The tissue culture and morphology of human breast tumor cell line BOT-2.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

A continuous human breast tumor cell line (BOT-2) was derived from an infiltrating duct carcinoma. The tumor cell line was grown as a monolayer in flasks, but the cells could be readily adapted to growth in roller cultures. These studies indicate that BOT-2 cells have a 16- to 18-hr doubling time and a modal chromosomal number of 63. The original BOT-2 cell culture has been in continuous cultivation for almost 2 years and has been passed 137 times. The BOT-2 cell line has been differentiated from HeLa cells by isoenzyme studies and chromosomal analysis.
OCCURRENCE OF DEPRESSION IN THE PATIENTS SUFFERING FROM CHRONIC INFECTION OF HEPATITIS C VIRUS

Field: Medicine (Health Sciences)

Objectives: The aim of this research work is to find out the rate of occurrence of depression in the patients suffering from chronic HCV infection prior to interferon treatment utilizing the CES-D questionnaire. Methodology: The positive patients for antibodies of hepatitis C virus with the utilization of the EIA for duration of more than six months and who did not obtain interferon treatment were the part of this research work after giving their written consent. The patients who were suffering from co-existing infections like hepatitis B &D virus or HIV virus, or the patients available with other co-occurring liver diseases as cirrhosis, auto-immune hepatitis and Wilson disease were not the part of this research work. CES-D in Urdu version managed to collect the information. Ascore of greater than ten was the standard for consistent with the availability of depression. Results: Total 96 patients were the part of this research work in which 59.40% patients were available with depression. There were 57.90%males &42.10% females in this research work. We saw the high occurrence in the under-graduate’s students & there was a positive association with the duration of the HCV infection. Conclusions: The findings of this research work showed that 59.40% patients suffering from HCV infection were available with depression before the start of therapy it necessary to assess and treat this issue before the start of the interferon treatment. KEY WORDS: Interferon, Treatment, Utilization, HCV Infection, Depression, EIA.
Co-Evaluating Landscape as a Driver for Territorial Regeneration: The Industrial Archaeology of the Noto–Pachino Railway (Italy)

Field: Social Sciences (Social Sciences)

This contribution investigates the potential and the catalytic role of landscape and its collective values in driving territorial regeneration processes. Specifically, it reflects on how the public dimension of landscape—conceived as a shared space of identity, memory, and future-oriented practices—can serve as a strategic lever for initiating local development pathways. Local communities, as custodians of the knowledge and practices that have historically shaped cultural landscapes, are increasingly recognized by territorial policies for their participatory and generative capacity. Building on these premises, the research explores the case of the disused Noto–Pachino railway line, located in southeastern Sicily (Italy), as a living laboratory for testing collaborative strategies aimed at enhancing landscape value and fostering territorial cohesion. The ongoing investigation has identified several civic and grassroots initiatives seeking to reactivate this dormant infrastructure, repositioning it as a strategic asset for sustainable territorial enjoyment, cultural heritage promotion, and the revitalization of marginalized areas. The main objective of the study is to define an “action lab”—a collaborative framework capable of aligning diverse visions, actors, and resources—through which landscape can be reimagined as both a driver of social innovation and a foundational tool for shaping inclusive and resilient development scenarios.
Evaluation of blackgram (Vigna mungo) genotypes for drought tolerance under field and in vitro conditions

Field: Agricultural and Biological Sciences (Life Sciences)

Blackgram a rainfed crop often experiences soil moisture deficit that reduces productivity to a large extent, could overcome by using a suitable drought resistant variety. Based on this, the present investigation was carried out during 2018 at Department of Genetics and Plant Breeding, Faculty of Agriculture, Annamalai University to study the drought tolerance in twenty-one blackgram genotypes. The selected genotypes (IC-343943, IC-343947, IC-343962, ABG-11013, KU-11680, TBG-104, VBG-10010, VBG-11011, VBG12005, VBG-12062, VBG-13017, ADT-5, RU-16-9, RU-16-13, RU-16-14, KGB-28, T-9, VBN(Bg)-4, VBN(Bg)-6, VBN(Bg)-7, MDU Local) were evaluated in the field condition for drought tolerance by imposing water stress during flowering and pod setting stages (4060 days after sowing) of the crop. The screening was also carried out in vitro by using PEG6000 at three concentrations viz., 0 bar, -3 bars and -6 bars to assess their seedling response under induced osmotic potential. Reduced growth was observed in all blackgram genotypes for all the characters except for the number of days to first flowering. Based on per se performance of genotypes under water-stressed field condition, the genotypes VBG12005, IC-343943 and IC-343947 were recommended as drought-tolerant genotypes for seed yield. In vitro condition, reduction in germination percentage, plumule and radicle length and biomass yield observed under increasing polyethylene glycol (PEG) induced water stress. In vitro screening of blackgram genotypes using PEG 6000 found that the genotypes VBG-11011, RU-16-9 and VBG-13017 expressed tolerance to drought at seed germination level. Thus, seedling stage screening for drought tolerance alone is not reliable as the tolerance mechanism may vary at different growth stages.
Inventory of non-timber forest product plant and fungal species in the Robson Valley

Field: Environmental Science (Physical Sciences)

Increasing interest in non-timber forest products (NTFPs) has led to their greater recognition in sustainable forest management planning. This is evident in local resource management plans for the Robson Valley in east-central British Columbia, where public input shows strong support for the sustainable development of NTFPs harvesting. However, information needed to develop sustainable management guidelines for NTFPss is currently lacking. We, therefore, undertook an inventory of non-timber forest product plant and fungal species in the Robson Valley.The distribution and abundance of NTFPs plant species was determined by ecosystem types as described by the Biogeoclimatic Ecosystem Classification system used in British Columbia. Species with a relatively high abundance and commercial potential included the valuable medicinal plant Devil�s club (Oplopanax horridus), berry-producing species such as black huckleberry (Vaccinium membranaceum), and the edible ostrich fern (Matteuccia struthiopteris). Plants used for floral greenery that are relatively abundant in certain ecosystem types included falsebox (Paxistima myrsinites), tall Oregon-grape (Mahonia aquifolium), pearly everlasting (Anaphalis margaritacea), and conifer boughs, especially from western redcedar (Thuja plicata). We identified a number of fungal species noted for their food, medicinal, wildcrafting, industrial, or traditional uses. Among the important food mushrooms we recorded in the Robson Valley were pine mushroom (Tricholoma magnivelare), hedgehog mushroom (Hydnum repandum), and black morel (Morchella elata).Several information gaps were identified. We recommend that future research focus on gathering detailed information about selected NTFPs species. Information describing habitats, growth requirements, production levels, and response to harvesting is needed to develop sustainable management strategies.
Is Rehabilitation Essential in the Probation Service in West Bengal?

Field: Social Sciences (Social Sciences)

All the Probation Service Agencies adopt a rehabilitation programme to help the probationers for their ultimate return to normal life. This author from his study of probationers regarding their socioeconomic conditions in West Bengal, India, asks: "Is rehabilitation essential in Probation Service?" The study is based on (1) official data, (2) house-to-house survey, and (3) field observations.
Spectroscopic investigations of the single tryptophan residue and of riboflavin and 7-oxolumazine bound to lumazine apoprotein from Photobacterium leiognathi

Field: Chemistry (Physical Sciences)

Spectroscopic techniques have been applied to investigate the conformation, local structure, and dynamic properties of the apoprotein of the lumazine protein from Photobacterium leiognathi and the holoprotein reconstituted with either the natural ligand 6,7-dimethyl-8-ribityllumazine or the closely related analogues riboflavin and 6-methyl-7-oxo-8-ribityllumazine (7-oxolumazine). The analogues are bound similarly to the natural prosthetic group. They exhibit similar shifts on binding in their absorption and fluorescence spectra, single-exponential fluorescence decays, and no independent motion from the protein as evident from a long-lived anisotropy decay (single-exponential phi = 10 ns, 20 degrees C) and high initial anisotropy. Steady-state anisotropy measurements result in similar KD's (40 nM, 20 degrees C, 50 mM inorganic phosphate) for all ligands. Circular dichroism in the far-UV region (190-250 nm) indicates no change in secondary structure on binding to the apoprotein. In the spectral region of 250-310 nm relatively large changes occur, indicating changes in the environment of the tyrosine and tryptophan residues. The single tryptophan residue shows a three-exponential decay of its fluorescence in both the apoprotein and the holoprotein. Radiationless energy transfer also occurs from the tryptophan to the bound ligand, especially evident with 7-oxolumazine. We have designed a new method for evaluation of the rate constant of energy transfer by measuring the (picosecond) rise time of the acceptor fluorescence. The anisotropy decay of the tryptophan residue shows two correlation times, a short one (phi approximately equal to 0.4 ns) representing rapid but restriced oscillation of this residue and a longer one (phi 2 = 5-7 ns, 20 degrees C) representing the motion of a larger segment of the protein.
Reports of the dollar's demise greatly exaggerated

Field: Economics, Econometrics and Finance (Social Sciences)

▀ Speculation that the dollar could lose its status as the world's main reserve currency “sooner rather than later” i looks, in our view, wide of the mark. Across a range of international uses, the dollar accounts for 40–60% of transactions – a share that has been stable or even increasing in recent years. Potential rivals are far behind, especially the Chinese renminbi, which accounts for just 1–2% of transactions. As a result, the dollar's pre‐eminence looks unlikely to be seriously threatened for many years to come. The US's gains from the dollar's global role may also be more modest than often thought. ▀ The dollar's position is supported by factors including its widespread use as a trading and commodity‐pricing currency, the size and liquidity of US financial markets, and the continued lack of a credible rival. None of these is likely to be significantly eroded in the near term, even with some moves afoot to shift away from dollar payments in oil and other areas. Historical evidence suggests that a world of multiple reserve currencies is possible but also shows it can take decades for reserve currencies to lose their dominant status.
Illicium parviflorum Anise, Yellow Anisetree, Star Anise

Field: Agricultural and Biological Sciences (Life Sciences)

This document provides an insightful overview of the longstalk holly, a broadleaf evergreen native to East Asia. It highlights the plant’s ornamental qualities, such as its smooth leaves, pyramidal shape, and red fruits that attract birds. The text also discusses the longstalk holly’s growth preferences, including its partial shade requirement and tolerance to wind and cold. The document concludes with potential landscaping applications for the plant, emphasizing its suitability for hedges, screens, and container plantings. Original publication date October 1999.
Analisis Non Performing Financing, Dana Pihak Ketiga, Capital Adequacy Ratio, Dan Financing To Deposit Terhadap Total Pembiayaan

Field: Economics, Econometrics and Finance (Social Sciences)

This research aims to examine the effect of Non-Performing Financing (NPF), Third Party Fund (DPK), CAR and FDR both simultaneously or partially on Total Financing with Islamic General Bank. In this research, the researcher applied quantitative method and employed secondary type of data sources. The sample used in this research is financial statement Islamic General Bank during the period of 2013-2017. The data analysis method used in this research is variable descriptive statistics, classic assumption test, multiple linear regression with significance level 5% and hypothetical test. The outcome of the research is processed using SPSS program version 22
Achieving Employment Equity in the Public Service: a study of changes between 1995 and 2001

Field: Social Sciences (Social Sciences)

This paper will seek to analyse the performance of the public sector in implementing affirmative action policies intended to promote employment equity. This will be done primarily by examining the pattern of changes in public sector employment over the past five years. Wherever possible, public sector employment data will also be benchmarked against the performance of the economy as a whole, as well as the public sector targets set by the South African Government. This research paper is sponsored by USAID and administered by the Joint Centre for Political and Economic Studies Inc. under a subcontract agreement from Nathan Associates Inc.
Effect of Panax Notoginseng Saponins on Serum Inflammatory Factor in Rats with Severe Acute Pancreatitis

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective:To investigate the effects of panax notoginseng saponins(PNS)on serum tumor necrosis factor(TNF)-α、 interleukin(IL)-6 and IL-10 levels in rats with severe acute pancreatitis(SAP),and to offer the theoretical basis in the treatment of SAP. Methods:SD rats were randomly divided into sham group,SAP group and PNS therapy group and 30 for each group. The serum amylase,TNF-α,IL-6 and IL-10 were determined at 6,12,24 hours after operation,the pancreatic histological changes and the mortality at 48 hours after operation in each group were observed also. Results:The serum amylase、 TNF-α、 IL-6 and IL-10 levels in the SAP group at each time point were significantly higher than those in the sham group(P0.01). The serum amylase,TNF-α and IL-6 levels in the PNS therapy group at each time point were significantly lower than those in the SAP group(P0.05),but the level of IL-10 was significantly higher than that in the SAP group(P0.05). The panthologic injuries in pancreas in the PNS therapy group were milder than those in the SAP group. The mortality at 48 hours in the sham group and PNS therapy group were significantly lower than that in the SAP group(P0.05). Conclusion:PNS has the therapeutic effect on SAP by decreasing the levels of TNF-α、 IL-6 and increasing IL-10.
Natural Product Extracts of Plant and Marine Origin Having Antileukemia Potential. The NCI Experience

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

While effective treatments exist for acute lymphocytic leukemia (ALL), particularly in the case of children, and for chronic mylogenous leukemia (CML), more efficacious treatments for other forms of acute and chronic forms of the disease are still needed. The National Cancer Institute has tested over 90,000 extracts of terrestrial plants and marine plants and invertebrates in its human cancer one-dose/60-cell-line prescreen, and the results for plants and marine organisms meeting criteria established for activity against selected leukemia cell lines are presented. Taxonomic data are limited to family and genus in the case of plants, and phylum for marine organisms, and those groups of organisms exhibiting significant activity (so-called "hot" families and genera) are discussed. The "hot" terrestrial plant families Myrsinaceae and Sapindaceae have not been studied to any extent and appear to merit special attention, although leukemia cell line selectivity is also noted for other families.
Relationship between connexin 36 protein and PDZ domain of zonula occludens protein 1

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Objective: To investigate the interaction between connexin 36 (Cx36) and PDZ domains of zonula oc-cludens 1 (ZO-1). Methods: PDZ domains fusion protein linked to GST in pGEX-3X recombinant vectors were expressed in E. coli DH5α(induced by IPTG). The purified protein was examined with Western blotting. The same PVDF membrane was stripped, reprobed with anti-GST and stained with coomassie blue. Results: pGEX-3X recombinant vectors were constructed. Cx36 transfected HeLa cells incubated with ZO-1 PDZ domains showed that Cx36 bound to PDZ1 domain of ZO-1. In contrast, Cx43 transfected HeLa cell incubated with ZO-1 PDZ showed that Cx43 bound to PDZ2 domain of ZO-1. Membranes were stripped and reprobed with anti-GST, showing one band migrated at 40 000-42 000. Stained with coomassie blue, the membrane revealed the equal loading of GST-PDZ fusion proteins. Cx36 also bound to PDZ1 domain of ZO-1 in mouse retina and Cx43 bound to PDZ2 domain of ZO-1 in mouse brain. Fusion protein was detected in the membranes with anti-GST and coomassie blue. Conclusion: Cx36 can interact with PDZ1 domain of ZO-1.