jimnoneill/paper-to-field-training huggingface dataset:
Adaptive optimisation driven deep belief networks for lung cancer detection and severity level classification

Field: Medicine (Health Sciences)

Computed tomography (CT) for lung cancer detection is trending research in determining the lung cancer on its earlier stages. However, accurate lung cancer detection with severity levels is a major challenge faced by most of the existing methods. This paper proposes a lung cancer detection model for analysing the severity levels using the CT images. The input CT images are obtained from the input lung cancer database using which the lung cancer detection and severity level classification is performed. The shape local binary texture (SLBT) is employed, which is generated by combining local directional pattern (LDP) and linear binary pattern (LBP), which is extracted from the nodules. The features are subjected to proposed adaptive-SEOA-DBN, which is the integration of adaptive-salp-elephant herding optimisation algorithm (adaptive-SEOA) in DBN for effective training of the model parameters. The proposed adaptive-SEOA is developed by combining self-adaptive concept in the SEOA. Finally, severity level classification is done to declare the severity of patient. The effectiveness of the proposed adaptive-SEOA-DBN is revealed based on maximal accuracy of 96.096 and minimal false detection rate (FDR) of 0.019, minimal false positive rate (FPR) of 4.999, and maximal true positive rate (TPR) of 96.096, respectively.
Concerning the catalytic site of porphobilinogen deaminase

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConcerning the catalytic site of porphobilinogen deaminaseA. I. Scott, N. J. Stolowich, H. J. Williams, M. D. Gonzalez, C. A. Roessner, S. K. Grant, and C. PichonCite this: J. Am. Chem. Soc. 1988, 110, 17, 5898–5900Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August 1988https://pubs.acs.org/doi/10.1021/ja00225a051https://doi.org/10.1021/ja00225a051research-articleACS PublicationsRequest reuse permissionsArticle Views92Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Adolescent Kawasaki disease shock syndrome with inflammatory cell infiltration into the myocardium: a case report

Field: Medicine (Health Sciences)

Abstract Background Kawasaki disease (KD) is a self-limiting form of systemic vasculitis. KD usually occurs in infants and young children and is rarely seen in adolescents. On rare occasions, KD is accompanied with reduced organ perfusion due to systolic hypotension, a condition known as Kawasaki disease shock syndrome (KDSS). The multifactorial causes of KDSS may include intensive vasculitis with capillary leak, myocardial dysfunction, and release of proinflammatory cytokines. However, the mechanisms underlying the pathophysiology of KDSS have not been fully elucidated. Case summary A febrile 17-year-old male with cervical lymphadenopathy developed extreme shock with rapid cardiac dysfunction and reduced organ perfusion. Electrocardiogram revealed ST elevation in the precordial leads and increased serum levels of cardiac enzyme levels. Endomyocardial biopsy at the acute phase revealed CD3+, CD4+ or CD8+, and CD20− lymphocytes and CD68+ macrophages within infiltrates in the myocardium with mild interstitial fibrosis. He was treated with intravenous immunoglobulin (IVIG) and followed by glucocorticoids with mechanical circulatory support. His cardiac function recovered rapidly with no apparent adverse effects. Discussion Our results suggest that KDSS may be a form of myocarditis, a condition in which inflammatory cells infiltrate the myocardium. Early immunosuppressive therapy, including IVIG and glucocorticoid therapy, may limit the severity of disease and improve the prognosis. As shown by this case, an accurate diagnosis of KD and KDSS will lead to early intervention and improved prognosis even among those in an older cohort.
Attention span during lectures: 8 seconds, 10 minutes, or more?

Field: Social Sciences (Social Sciences)

In the current climate of curriculum reform, the traditional lecture has come under fire for its perceived lack of effectiveness. Indeed, several institutions have reduced their lectures to 15 min in length based upon the “common knowledge” and “consensus” that there is a decline in students’ attention 10–15 min into lectures. A review of the literature on this topic reveals many discussions referring to prior studies but scant few primary investigations. Alarmingly, the most often cited source for a rapid decline in student attention during a lecture barely discusses student attention at all. Of the studies that do attempt to measure attention, many suffer from methodological flaws and subjectivity in data collection. Thus, the available primary data do not support the concept of a 10- to 15-min attention limit. Interestingly, the most consistent finding from a literature review is that the greatest variability in student attention arises from differences between teachers and not from the teaching format itself. Certainly, even the most interesting material can be presented in a dull and dry fashion, and it is the job of the instructor to enhance their teaching skills to provide not only rich content but also a satisfying lecture experience for the students.
Case Series: Soft-tissue nail-fold excision: a definitive treatment for ingrown toenails.

Field: Medicine (Health Sciences)

Background
Ingrown toenail, or onychocryptosis, is a common source of morbidity worldwide. The current standard of care focuses on the nail as the causative agent, and, in cases that are resistant to medical management, surgical correction via nail avulsion and phenol matrix ablation is used. Unfortunately, this treatment leads to poor cosmetic results, high rates of recurrence and low patient satisfaction.
Pentingnya Peningkatan Gizi Anak Berbasis Pangan Lokal

Field: Health Professions (Health Sciences)

The local-based program to improve nutrition for children is one of the efforts to strengthen families by maintaining local-based food security. This program aims to increase family knowledge and skills regarding the use of land or home gardens by planting local plants that contain high nutrients and processing locally based food ingredients. The program implementation method involves identifying the potential of village community land, identifying problems, socializing and training on desert management based on local fruit. The results of implementing the community work program can process local food ingredients and fruit into food menus that can improve children's nutrition, understand the nutritional content of local fruit, and prepare land for planting local fruit. Indirectly, this program can be useful in increasing the knowledge of mothers and childrasn initial step in preventing stunting.
Protein-induced bonding perturbation of the rhodopsin chromophore detected by double-quantum solid-state NMR.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

We have obtained carbon-carbon bond length data for the functional retinylidene chromophore of rhodopsin, with a spatial resolution of 3 pm. The very high resolution was obtained by performing double-quantum solid-state NMR on a set of noncrystalline isotopically labelled bovine rhodopsin samples. We detected localized perturbations of the carbon-carbon bond lengths of the retinylidene chromophore. The observations are consistent with a model in which the positive charge of the protonated Schiff base penetrates into the polyene chain and partially concentrates around the C13 position. This coincides with the proximity of a water molecule located between the glutamate-181 and serine-186 residues of the second extracellular loop, which is folded back into the transmembrane region. These measurements support the hypothesis that the polar residues of the second extracellular loop and the associated water molecule assist the rapid selective photoisomerization of the retinylidene chromophore by stabilizing a partial positive charge in the center of the polyene chain.
Coating of NZVI Particles With Modified Starch: Colloidal Stability and Nitrate Reduction Studies

Field: Environmental Science (Physical Sciences)

Nanoscale-zero valent iron (NZVI) is an effective groundwater remediation media because it can quickly reduce and absorb contaminants. However, NZVI quickly agglomerates in aqueous systems, reducing its remediation capacity. This work investigated coating NZVI with native and modified rice, wheat, maize, and tapioca starches to improve colloidal stability. Colloidal stability studies were conducted with native and commercially available starches; tapioca starch modified with 2-Octen-l-ylsuccinic anhydride (OSA) was the best. Four concentrations of OSA-tapioca starch were prepared (3, 15, 35, and 50% w/w). NZVI coated with 35% OSA-modified tapioca starch (concentration = 10 g L-1) kept 66% of the coated particles suspended after 2 hours (compared to 4% of bare particles, p = 0.000). Bare NZVI reduced significantly more nitrate (20 mg L-1) than coated NZVI (p =0.000). Bare and coated NZVI provided the same nitrate reduction at 40 and 60 mg L-1 (p = 0.939 and p = 0.815, respectively).
Analysis of distribution tariff structures in the presence of non-linear load

Field: Energy (Physical Sciences)

In restructured power systems, distribution pricing has emerged as a vital driver to ensure economic efficiency of network operations. An increasing emphasis is being laid on the design of cost-reflective tariff structures so as to send appropriate economic signals to electricity consumers. Furthermore, with changing load profile and injection of large harmonic currents by the consumers in present distribution systems, designing an efficient tariff structure is a challenging task This paper investigates two most widely used tariff structures, viz. two-part and three-part, in the presence of non-linear load. Demand power and energy are calculated with varying percentage of non-linear load in the distribution system, and annual distribution price for both tariff structures is compared. Test results obtained for IEEE -18 bus radial distribution system indicate that three-part distribution tariff structure is significantly cost-reflective as compared to the two-part structure.
On Acceptability, Career Commitment and Special Accommodation To Women Programmer: Gender Based Perspective

Field: Psychology (Social Sciences)

Gender seemed to have important role in choosing a job in the computer related works. Women graduated from a computer college are less interested in working as computer programmer, although they are given special privileges. The objective of this study is to examine if there are differences on perception such as acceptability, career commitment and women special accommodation/privileges on marital and maternity leaves, between men and women graduates.The issue above is empirically tested by asking both men and women alumni directly using electronic-questionnaires. Statistical test was utilized to test differences on their answers. It is found that there are slight differences between the issue of acceptability, while there are no differences on the issue of career commitment and special or particular accommodation between men and women alumni. Larger part of the respondents expressed that working women should have the same career commitment as their men counterparts. In addition, special accommodation should also be given to them since they are unique individuals.
Immunotherapy for Gliomas

Field: Medicine (Health Sciences)

Ms. Bower is a Medical Student, Dr. Lim is Chief Resident, and Dr. Harsh is Professor, Department of Neurosurgery, Stanford University Medical Center, 300 Pasteur Drive, Boswell Building, A301, Stanford, CA 94305-5327; E-mail: [email protected]. The authors have disclosed that they have no significant relationships with or financial interests in any commercial organizations pertaining to this educational activity. Lippincott CME Institute, Inc., has identified and resolved all faculty conflicts of interest regarding this educational activity. Category: Tumor
Session 1F The Republic of Vanuatu

Field: Environmental Science (Physical Sciences)

Vanuatu is a chain of islands in the South Pacific.The country is highly reliant economically and culturally on the marine and coastal areas, specifically the Vanuatu Snapper (Paracaesiogonzalesi). The Vanuatu Snapper as an ecological indicator intersects closely with severa lSustainable Development Goals, including SDG 6: Clean Water and Sanitation, SDG 14: Life Below Water, and SDG 12: Responsible Consumption and Production. Ultimately, under the INDC Vanuatu is working towards these SDGs in orderto conserve the Vanuatu Snapper, protect the country's economy, and contribute to bettering the issues developing with climate change.
The Study and Investigation of Self-directed Learning of Distance Learners

Field: Social Sciences (Social Sciences)

According to the four characteristics of open and distance education, including open, adaptability, variety and efficiency. This article mainly investigates and analyzes how to improve the qualities of students' self-directed learning. To learn about web-based self-directed learning of students in distance education, we make questionnaires to investigate some learners who are learning web-based courses. Based on the data, the author puts forward some ideas and suggestions.
Hubungan Kepemimpinan Transformasional Kepala Sekolah, Komunikasi Organisasi, Komitmen Organisasi dengan Kinerja Guru SMK Negeri di Kota Malang

Field: Social Sciences (Social Sciences)

Abstract: The research was conducted (1) to describe transformational leadership, organizational communication, organizational commitment, and teacher performance, (2) to determine the direct and indirect relationship between principal transformational leadership, organizational communication, organizational commitment, teacher performance. This subject in this research was 207 PNS teachers in SMKN Kota Malang. Researcher used quantitative methods which was descriptive and correlational. Researcher distributed 107 questions of questionnaires. The results showed that (1) transformational leadership, organizational communication, organizational commitment was high, meanwhile teacher performance was higher, (2) there was a positive and significant direct and indirect relationship in the variables studied, except the transformational leadership of principals wirh teacher performance. Abstrak: Penelitian ini dilakukan (1) untuk mendeskripsikan kepemimpinan transformasional kepala sekolah, komunikasi organisasi, komitmen organisasi, dan kinerja guru, (2) untuk mengetahui hubungan langsung dan tidak langsung antara kepemimpinan transformasional kepala sekolah, komunikasi organisasi, komitmen organisasi, dan kinerja guru. Subyek dalam penelitian ini berjumlah 207 guru PNS di Kota Malang. Penelitian menggunakan metode kuantitatif bersifat deskriptif dan korelasional. Adapun hasil dari penelitian ini yakni (1) kepemimpinan transformasional, komunikasi organisasi, komitmen organisasi termasuk dalam kategori tinggi, sedangkan kinerja guru sangat tinggi, (2) adanya hubungan langsung dan tidak langsung positif dan signifikan pada variabel yang diteliti, kecuali pada variabel kepemimpinan transformasional kepala sekolah dengan kinerja guru.
Effect of Dehydration on Pollen Germination in Vitro and Storage Character of Platycodon Grandiflorum

Field: Agricultural and Biological Sciences (Life Sciences)

A metrical way of pollen activity by pollen germination in vitro was adopted to evaluate effect of dehydration on pollen activity of platycodon grandiflorum.Seed setting of pollen after the treatment of the dehydration and storage was estimated by artificial pollinating.This paper was given the base for storing pollen.The results showed that the pollen germination were best at 30℃ for 1.5 hours.Germination and tube length of pollen decreased after the treatment of the dehydration,with the smallest decline of pollen activity after treatment of dehydration in oven for 1.5 hours to 2 hours.Furthermore,storability of pollen after treatment of dehydration in oven for 2 hours was longest than other treatments.Changes of seed setting of pollen after different treatment were different significantly.Seed setting of pollen with treatment of dehydration for 2 hours in the shade was lowest,and seed setting of pollen was almost same with treatments for 6 hours in desiccator,for 2 hours in the sun and for 1.5 hours in oven.Seed setting of pollen were decreased with the delaying of storage time,and seed setting of pollen with treatment for 1.5 hours in oven after 5 days under normal temperature was 11.5%,and its seed setting was higher than others significantly.
Proceedings of the Third International Symposium on Orbital Disorders

Field: Medicine (Health Sciences)

The third international symposium on orbital disorders was held in Amsterdam Sept 5 through 7, 1977. The majority of papers were devoted to modern diagnostic modalities for orbital disorders. Several excellent papers on echography were presented, including a detailed and inclusive summary of orbital echography by Dr Karl Ossoinig. A number of papers discuss the recent advances in computerized axial tomography for orbital disorder diagnosis and several compare the efficacy of this modality vs other diagnostic modalities. Several interesting papers on thyroid-related eye disease and its diagnosis and treatment were presented. The superiority of the thyrotropin-releasing hormone test in comparison with other blood studies were demonstrated. A number of studies on blowout fractures were presented, including several discussing the mechanism of injury. Also included in the proceedings are several fascinating papers on individual cases.
Genotype x Environment Interaction and Stability Analysis for Gran Yield of Diallel Cross Maize Hybrids Across Tropical Medium and Highland Ecologies

Field: Agricultural and Biological Sciences (Life Sciences)

Genotype x environment (G x E) interaction is the differential performance of genotypes across environments, especially in the tropics where seasonal and spatial variability is large. This results in serious challenges of product selection across environments. The objectives of this study were to determine G x E interaction and yield stability of new diallel cross maize hybrids and to identify suitable genotypes for the medium and highland ecologies in Rwanda. Forty- five diallel cross maize hybrids and three commercial checks were evaluated in four locations representing the major agro-ecologies of Rwanda over three seasons. The data were subjected to genotype and genotype by environment interaction (GGE) biplot analysis, using Genstat statistical package. The analysis revealed two mega-environments which discriminated the hybrids. Two genotypes 3 (S1/S4) and 25 (S4/S5) displayed specific adaptation; qualifying them as candidates for further testing in respective mega-environments. Genotypes 3 (S1/S4) and 29 (S4/S9) demonstrated high yield and stability. Overall, the study revealed crossover interaction and there is need to breed for both broad and specific adaptation in these medium and high altitude environments.
New Engineered-Botulinum Toxins Inhibit the Release of Pain-Related Mediators

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Targeted delivery of potent inhibitor of cytokine/pain-mediator into inflammatory or pain-sensing cells is a promising avenue for treating chronic pain, a world-wide major healthcare burden. An unmet need exists for a specific and effective delivery strategy. Herein, we describe a new approach using sortase to site-specifically ligate a non-toxic botulinum neurotoxin D (BoNT/D) core-therapeutic (synaptobrevin-cleaving protease and translocation domains) to cell-specific targeting ligands. An engineered core-therapeutic was efficiently ligated to IL-1β ligand within minutes. The resultant conjugate specifically entered into cultured murine primary macrophages, cleaved synaptobrevin 3 and inhibited LPS/IFN-γ evoked IL-6 release. Likewise, a CGRP receptor antagonist ligand delivered BoNT/D protease into sensory neurons and inhibited K+-evoked substance P release. As cytokines and neuropeptides are major regulators of inflammation and pain, blocking their release by novel engineered inhibitors highlights their therapeutic potential. Our report describes a new and widely-applicable strategy for the production of targeted bio-therapeutics for numerous chronic diseases.
Semi-Autonomous Control of Drones/UAVs for Wilderness Search and Rescue

Field: Engineering (Physical Sciences)

Wilderness search and rescue (WiSAR) has been one of the most significant robotic applications in the past decade. In order to succeed in these life-saving operations, the deployment of drones or unmanned aerial vehicles (UAVs) has become an inevitable trend. This paper presents the development of a low-cost solution for semi-autonomous control of drones/UAVs in WiSAR applications. ArduPilot based flight controller was implemented to enable autonomous trajectory following of the drones/UAVs. A high resolution action camera attached to the drone/UAV was used to take video footage during the flight, which was related to the GPS location through the time stamp. The recorded video footage was manually transferred to a laptop for potential target detection using OpenCV and YOLOv3. The system design is reported in detail, and experiments were conducted to verify the effectiveness of the developed system.
Performance, diagnostics, controls and plans for the gyrotron system on the DIII-D tokamak

Field: Physics and Astronomy (Physical Sciences)

The DIII-D ECH complex is being upgraded with three new depressed collector gyrotrons. The performance of the existing system has been very good. As more gyrotrons having higher power are added to the system, diagnostics of gyrotron operation, optimization of the performance and qualification of components for higher power become more important. A new FPGA-based gyrotron control system is being installed, additional capabilities for rapid real time variation of the rf injection angles by the DIII-D Plasma Control System are being tested and infrastructure enhancements are being completed. Longer term plans continue to include ECH as a major component in the DIII-D heating and current drive capabilities.\n