jimnoneill/paper-to-field-training huggingface dataset:
A stable U-band VCO in 65 nm CMOS with -0.11 dBm high output power

Field: Engineering (Physical Sciences)

A high output power voltage controlled oscillator (VCO) in the U-band was implemented using a 65 nm CMOS process. The proposed VCO used a transmission line to increase output voltage swing and overcome the limitations of CMOS technologies. Two varactor banks were used for fine tuning with a 5% frequency tuning range. The proposed VCO showed small variation in output voltage and operated at 51.55-54.18 GHz. The measured phase noises were -51.53 dBc/Hz, -91.84 dBc/Hz, and -101.07 dBc/Hz at offset frequencies of 10 kHz, 1 MHz, and 10 MHz, respectively, with stable output power. The chip area, including the output buffer, is 0.16×0.16 ㎟ and the maximum output power was -0.11 dBm. The power consumption was 33.4 mW with a supply voltage of 1.2-V. The measured FOMSUBP/SUB was -190.8 dBc/Hz.
Ethanol Suppresses the Effects of Sodium Arsenite in Male Wister Albino Rats

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Background: Millions of people around the world get exposed to high levels of heavy metals in drinking-water.Therefore, quality control in drinking-water, food industries and detection of heavy metals is an extremely critical issue in maintaining the human health.Of such heavy metals is arsenic.Water as one of the major ingredient in both traditional and modern beer fermentation process may/may not be contaminated with arsenic due to poor quality control.As a result people are exposed to the end product which constituted arsenic compound.Sodium arsenite and ethanol has been established to be toxic both in vivo and in vitro.Objective: This study is primarily designed to investigate the effect of co-administration of sodium arsenite and ethanol in male Wister albino rats.Methods: Forty five (45) albino rats divided into nine (9) groups of five rats each were administered with distilled water, 2.5mg and 5mg/kg body weight of sodium arsenite, 3% and 6% (v/v) respectively.Treatment was based on single and combined administration.Micronucleated polychromatic erythrocytes, acetylcholine esterase, Aspartate Transaminase (AST), Alkaline Phosphatase (ALP), Alanine Transaminase (ALT) and hematological parameters were determined by standard procedures (Figure 1). Results:Combined treatment with sodium arsenite and ethanol significantly decreased the number of micro nucleated polychromatic erythrocytes, AST, ALT and ALP activities as against the single treated groups.However, there was stabilization of acetylcholine esterase activity in the brain.The hematological parameters level was also stabilized. Conclusions:We therefore proposed that the chemical interaction between sodium arsenite and ethanol is what was responsible for the suppression of sodium arsenite -induced clastogenic, hepatotoxic, anti-acetylcholine esterase and anemic effects.
A Velocity Dealiasing Technique Using Rapidly Updated Analysis from a Four-Dimensional Variational Doppler Radar Data Assimilation System

Field: Earth and Planetary Sciences (Physical Sciences)

Abstract A Doppler velocity dealiasing algorithm is developed within the storm-scale four-dimensional radar data assimilation system known as the Variational Doppler Radar Analysis System (VDRAS). The innovative aspect of the algorithm is that it dealiases Doppler velocity at each grid point independently by using three-dimensional wind fields obtained either from an objective analysis using conventional observations and mesoscale model output or from a rapidly updated analysis of VDRAS that assimilates radar data. This algorithm consists of three steps: preserving horizontal shear, global dealiasing using reference wind from the objective analysis or the VDRAS analysis, and local dealiasing. It is automated and intended to be used operationally for radar data assimilation using numerical weather prediction models. The algorithm was tested with 384 volumes of radar data observed from the Next Generation Weather Radar (NEXRAD) for a severe thunderstorm that occurred during 15 June 2002. It showed that the algorithm was effective in dealiasing large areas of aliased velocities when the wind from the objective analysis was used as the reference and that more accurate dealiasing was achieved by using the continuously cycled VDRAS analysis.
Polyclonality and Multispecificity of the CTL Response to a Single Viral Epitope

Field: Immunology and Microbiology (Life Sciences)

Abstract The molecular anatomy of an immunodominant, Ld restricted CTL epitope located between residues 28–39 in hepatitis B surface Ag was defined to explore the immunologic constraints on mutational escape from the CTL response during a viral infection. Using a panel of hepatitis B surface Ag residue 28–39-specific CTL clones, the response to this epitope was found to be extremely diverse at the level of TCR fine specificity and β-chain usage. Although each clone recognized shared as well as unique residues within the epitope as TCR contact sites, even the shared residues were recognized differently by different TCRs. Despite these differences, all clones were comparably cytolytic following Ag stimulation and produced similar amounts of antiviral cytokines previously shown to inhibit HBV replication. These results demonstrate that the CTL response to individual viral epitopes can be markedly polyclonal and multispecific, such that mutational inactivation of a single TCR contact site will not usually lead to viral escape from all CTL clones of the same epitope specificity. Given these constraints and the fact that the CTL response is usually directed against several different epitopes during most viral infections, mutational inactivation of a single epitope is not likely to be sufficient to cause viral persistence.
Extremal quantile regression: an overview

Field: Mathematics (Physical Sciences)

Extremal quantile regression, i.e. quantile regression applied to the tails of the conditional distribution, counts with an increasing number of economic and financial applications such as value-at-risk, production frontiers, determinants of low infant birth weights, and auction models. This chapter provides an overview of recent developments in the theory and empirics of extremal quantile regression. The advances in the theory have relied on the use of extreme value approximations to the law of the Koenker and Bassett (1978) quantile regression estimator. Extreme value laws not only have been shown to provide more accurate approximations than Gaussian laws at the tails, but also have served as the basis to develop bias corrected estimators and inference methods using simulation and suitable variations of bootstrap and subsampling. The applicability of these methods is illustrated with two empirical examples on conditional value-at-risk and financial contagion.
Teleconsultation Apps in the COVID-19 Pandemic: The Case of Guayaquil City, Ecuador

Field: Health Professions (Health Sciences)

The new coronavirus disease (COVID-19) has affected a large part of the worldwide population, causing more than a million deaths between the end of 2019 until now. Technological development and digital tools arise to carry out activities remotely, either for monitoring or diagnosis. Medical teleconsultation activities are not new, but due to the pandemic situation that the COVID-19 originated, it has become a popular option to avoid going to consultations physically due to the risk of contagion. This article presents an analysis of different teleconsultation services implemented during the spread of the COVID-19 in the city of Guayaquil, Ecuador, as a case study. The methodology includes a performance assessment of the teleconsultation apps used during the critical periods of the pandemic. We detailed the fundamental stages deemed to verify that the fulfillment and knowledge about telemedicine in this city are not extensive enough in terms of remote health benefits. Throughout this article, we evidenced that the population is not prepared to manage remote-care systems due to the low use of technology and the lack of support from public or private agencies for providing technological development for medical services that satisfy the needs of the inhabitants.
Abstract 15427: Reduction of Epicardial Fat, Clinical Risk Factors & Symptomatology in Paroxysmal AF Patient With Severe Aortic Stenosis and Metabolic Syndrome via Mobile Cardiometabolic Health & Weight Loss Program

Field: Medicine (Health Sciences)

Atrial fibrillation (AF) is dependent on epicardial fat (EpF) accumulation and infiltration. Complementary therapeutic strategies specifically targeting EpF present an opportunity for slowing progression and reversing the course of AF. A 73-year-old man with a history paroxysmal AF (managed by rate control/anticoagulation), severe aortic valve stenosis (AVS, area 1cm 2 , EF 55%), controlled hypertension, diabetes, and obesity (BMI 37.9) completed a 2-month cardiometabolic health program (CHP). The ‘tech plus touch’ CHP, delivered via a smartphone, utilized a comprehensive approach with physiological, nutritional, and behavioral components. Along with patented dietary regimens and nutritional supplementation implemented with personalized treatment algorithms, the CHP included direct daily engagement (messaging & telehealth) with a staff clinician via the HIPAA compliant mobile app. Patient data visible to both the patient and staff clinician was synced automatically via Bluetooth-linked devices. EpF dropped by 25.5% over 9w (transthoracic echo, Fig1). BMI, visceral adiposity, and body fat were significant reduced, while lean body mass (LBM), muscle mass (MM) and intracellular fluid (ICF, a validated surrogate of chronic inflammation) improved (Fig1). Encouragingly, LBM, MM, and ICF improvements were unusual and particularly large in this older, physically inactive patient. Other clinical risk factors improved including diabetes, kidney function and inflammation. The patient reported resolution of chest pain and dyspnea, improved cardiorespiratory fitness, and began aerobic exercise. Our data demonstrate a nonpharmacologic complementary approach produces significant reductions of EpF and modifiable risk factors linked to hypertension, diabetes, and chronic inflammation in an AF patient with AVS and metabolic syndrome. Whether this will lead to a reduction in AF burden or conversion to persistent AF, remains to be determined.
CLUB PROGRAM/PROJECT REPORT - CONSERVATION - Environmental Action

Field: Environmental Science (Physical Sciences)

NAME OF CLUB - Thursday Study Club; DISTRICT - Trinity; CITY - Plano; CLUB CLASSIFICATION - General; PRESIDENT - Mrs. J. T. Uland; REPORT TITLE - CONSERVATION - Environmental Action; Number Programs - 1 ; Money Contributed - ; Number Projects - ; % Member Participation - 100; Number of Volunteer Hours - 5; CONSERVATION - Environmental Action -- The Plano Thursday Study Club's program on Conservation was concerned with environmental problems which affect all of us. It reached out to conservation of energy, natural resources and human resources, as well as touching on the beauties of the world around us. With care and concern for our environment the world can become more beautiful in every way for our children and our children's children. After discussing the importance of preserving and keeping all our individual homes in good condition, a club member reviewed the community aspect of public parks. She pointed out the uses of Plano's many parks. These parks provide not only beauty for our city, but they provide constructive recreation for all residents, especially our young people and older citizens. Plano has emphasized this aspect of parks. In this conservation program, all the members answered roll call with a bit of information on the fast disappearing wildlife. This brought out the importance of our natural resources and, especially, showed how American wildlife plays an important part in our environment. A program such as this helps to better inform club members of the overall conservation concerns in today's society and presents a great challenge to all people who are interested in America's future.
A simple and efficient method that uses low concentration fetal bovine serum to culture and purify Schwann cells

Field: Neuroscience (Life Sciences)

To develop a simple and efficient method for the isolation of highly purified Schwann cells (SCs) from the sciatic nerves of newborn rats, cells were initially cultured in 10% FBS for 6 days, and then cultured in 2% FBS for 6 days. And we used the immunocytochemical characterization, flow cytometry, RT-PCR, to observe the condition of SCs. After the 12-day treatment protocol, we obtained a high yield of SCs with an average purity of 96.9%. Furthermore, the condition of SCs had no change. In our purification protocol, we had shown that our procedures did not alter the cell cycle and neurokines’ secretion. Our simple and efficient method yielded pure and healthy SCs and did not require treatment with antimitotic agents or any special equipment.
Analysis of Microbiological Contamination in Ready-to-eat Foods

Field: Immunology and Microbiology (Life Sciences)

This study was carried out to examine microbiological contamination of ready-to-eat foods (kimbab, sushi, salad, sandwich,sashimi) and to prove hazard of ready-to-eat foods by microbiological analysis. Col- lection of 440 samples of ready-to-eat foods were obtained from department stores, discount stores, super-markets in Seoul, Gyeonggi, Chungcheong, Gyeongsang, Honam areas. Sushi showed the highest detection rate of microorgan- ism with value of 20.4%, and then detection rates of kimbab, sashimi and salad were 13.0%, 12.5% and 6.9%, respec- tively. S. aureus was the most detected microorganism with value of 6.6%, and then Coliform and L. monocytogenes were detected 2.7% and 2.3%.
A Dialogue Across the Circle

Field: Arts and Humanities (Social Sciences)

The circle in this chapter’s title is a symbol of the drama classroom and its ensemble. The chapter is constructed as a dramatic dialogue between Jane, a drama teacher, and her daughter Holly, a drama student. It arose from an embodied conversation as they reflected on their individual experiences of making theatre for assessment purposes at two separate secondary schools in Aotearoa, New Zealand. This chapter contributes to the global discussion about drama assessment in schools and whether it encourages or suppresses the act of aesthetic and purposeful theatre-making with young people. Jane and Holly focus on New Zealand’s assessment system, the National Certificate in Educational Achievement (NCEA). They discuss the ways in which students and teachers navigate their roles to create ‘authentic’ theatre in the restricted environment of a school where there are limits on resources, time, and space. As a young person, Holly’s voice is privileged as she considers the outcomes that she and her peers valued in the experience of NCEA theatre-making. Jane and Holly conclude that the presence of NCEA Drama in the curriculum has created a space for young people to create authentic theatre performances.
Moral Panic: Changing Concepts of the Child Molester in Modern America. By Philip Jenkins (New Haven and London: Yale University Press, 1998. xii plus 302pp.)

Field: Social Sciences (Social Sciences)

Journal Article Moral Panic: Changing Concepts of the Child Molester in Modern America. By Philip Jenkins (New Haven and London: Yale University Press, 1998. xii plus 302pp.) Get access Patrick J. Ryan Patrick J. Ryan University of Texas at Dallas Search for other works by this author on: Oxford Academic Google Scholar Journal of Social History, Volume 35, Issue 2, Winter 2001, Pages 511–513, https://doi.org/10.1353/jsh.2001.0138 Published: 01 December 2001
Redefining the Endophenotype Concept to Accommodate Transdiagnostic Vulnerabilities and Etiological Complexity

Field: Psychology (Social Sciences)

In psychopathology research, endophenotypes are a subset of biomarkers that indicate genetic vulnerability independent of clinical state. To date, an explicit expectation is that endophenotypes be specific to single disorders. We evaluate this expectation considering recent advances in psychiatric genetics, recognition that transdiagnostic vulnerability traits are often more useful than clinical diagnoses in psychiatric genetics, and appreciation for etiological complexity across genetic, neural, hormonal and environmental levels of analysis. We suggest that the disorder-specificity requirement of endophenotypes be relaxed, that neural functions are preferable to behaviors as starting points in searches for endophenotypes, and that future research should focus on interactive effects of multiple endophenotypes on complex psychiatric disorders, some of which are 'phenocopies' with distinct etiologies.
Yellow Flags

Field: Health Professions (Health Sciences)

Es wird allgemein akzeptiert, dass psychosoziale Faktoren beim Assessment und Management von Rückenschmerzpatient*innen berücksichtigt werden sollen. Viel weniger klar ist allerdings, wie genau dies in der Praxis umzusetzen ist. Zur Standortbestimmung untersuchten Autoren der ‚Musculoskeletal Rehabilitation Research Group‘ der ‚HAN University of Applied Sciences‘ im niederländischen Nijmegen die aktuellen internationalen Richtlinien hinsichtlich der Berücksichtigung von psychosozialen Faktoren als prognostische Faktoren. Der Fokus des Teams um Jesper Knoop als Erstautor lag dabei insbesondere auf den als „Yellow flags“ bekannten psychologischen Faktoren, konzentrierte sich aber auch auf andere Aspekte wie arbeitsplatzbezogene Risikofaktoren, „Blue flags“, das soziale Umfeld und die medizinische Versorgung betreffende Faktoren, „Black flags“, sowie psychiatrische Erkrankungen bzw. „Orange flags“. Wichtig ist, dass in dem systematischen Review auch die Evidenz für die in den Richtlinien enthaltenen Faktoren bewertet wurde. In 13 von 15 Richtlinien fanden Knoop et al. psychosoziale prognostische Faktoren bezüglich des Assessments von Rückenschmerzpatient*innen, in 14 Richtlinien auch Faktoren hinsichtlich des Managements. Letztere aber waren uneinheitlich. Zudem wurde das Evidenzniveau unisono – so auch bei den in Deutschland geltenden Richtlinien – als von „sehr geringer“ Qualität eingeschätzt.
Biochemical profile and resistance phenotype of bacteria isolated from the operating site departments of the National Reference University Hospital of N'Djamena

Field: Immunology and Microbiology (Life Sciences)

The aim is to assess the level of contamination of wound bacteria in operated patients in the surgical departments of the National Reference University Hospital (CHURN) of N’Djamena. From August 1, 2018 to August 1, 2019, an observational culture study on wound pus was carried out in patients operated on from the surgical services of the N’Djamena CHURN according to standard methods of medical microbiology. Of the 1092 patients operated on, 565 patients were released within a normal period of hospitalization and 527 in contact with the pathogens were maintained. Significant differences were observed between the proportions of positive (86%) and sterile (14%) cultures; female (30.36%) and male (69.63%) operated subjects with probabilities of 0.02 and 0.001 respectively. Escherichia coli were the most common germs (32.7%), followed by Staphylococcus spp (20.9%). The bacteria isolated were resistant to beta-lactam antibiotics at an average rate of 40%, only imipenem, a last-resort antibiotic, was very sensitive (99.5%). In view of these results, we recommend that prescribers avoid prescribing antibiotics without laboratory evidence for fear of losing the beta-lactams permanently.
Computer Aided Diagnosis of Abdomen Diseases Using Curvelet Transform

Field: Computer Science (Physical Sciences)

Abdomen related diseases are responsible of many deaths every year. These deaths can be reduced by early diagnosis of abdomen diseases. Computer aided diagnosis (CAD) can play vital role in early detection of diseases. Hence, a novel CAD is proposed in this paper that can diagnose abdomen diseases like Hepatocellular carcinoma, cysts and Calculi using statistical curvelet texture descriptors. The proposed CAD is divided into four stages: (a) Image segmentation using active contours, (b) feature extraction, (c) feature selection and (d) abdomen disease classification. The regions of interest (ROIs) are segmented from 120[Formula: see text]CT images using active contour models. The statistical features are extracted from segmented ROIs. Further, the classifiers are used to evaluate the ability of feature set in diagnosis various diseases of abdomen. The performance metrics indicates that the proposed CAD achieves accuracy of 87.9% using curvelet coefficient features and neural network as classifier.
"Cultural Layer of Kurgan City": Determination, Studying, Findings, Issues and Prospects"

Field: Arts and Humanities (Social Sciences)

Cultural Layer of Kurgan City archaeological monument was established in 2005. Since 2009 it has been exposed to archaeological excavations at different city mansions dated 1700s – early 1900s and situated within the determined site of cultural heritage. The article briefly describes 14 excavation sites. All works were subject to a commercial contract. It allowed to research relatively substantial areas of the monument. Excavations were arranged in various parts of the historic development including periphery. The research of the periphery is unlikely under the scheduled works. The article describes how the monument was detected and studied and what findings were made. The study reveals how the archaeological finds correlate with the discovered records of the main owners of these mansions. Cultural Layer of Kurgan City archaeological monument is a unique source of information about the tangible culture of citizens in the mid–1700s through the early site 1900s. The paper reviews how the monument was explored through the prospective of particular finds, natural science researches, construction technologies and particular serial sites. The authors generalize the ceramic production, glass production and hygiene in the area. The article outlines the key problems associated with inadequate research of the Cultural Layer of Kurgan City and inferior comparison of archives and archaeological materials. The total area of the monument is 978 thousand sq. m. Yet, due to various reasons it annually loses several thousand square meters with no hope of return.