jimnoneill/paper-to-field-training huggingface dataset:
FAM RECIMEN IN THE TREATMENT OF ADVANCED ADENOCARC I NOMA

Field: Medicine (Health Sciences)

5 3 advanced adenocarcinoma were treated with adjusted FAM(5-Fluorouracil , Adriamycin, Mitomycin), regimen and the overall response rate (RR) was 37.7% ( CR3, and PRl7). The best result was seen in mammary and gastric carcinoma (RR= 66.7% and 48.4% respectively), but the response rates for lung and Colo-rectal carcinoma were poor.The major toxic side effects were gestrointestinal tract and myelosuppfession , but the great majority was limited to 1-11 grade, and patients were tolerable.
Extracts of Selected Plants and Fruits Profoundly Modulate <i>In Vitro</i> Coagulation Activity

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Background: Plant products treat many diseases and are an important resource for pharmaceutical companies developing new medicines. Hemostasis maintains blood in the fluid state and prevents its loss from damaged blood vessels. Plants have been reported to be sources of anticoagulant and antithrombotic substances and are employed in the management of coagulation disorders. Aim: This study investigates the effects of aqueous and ethanolic extracts of bitter leaves, mango leaves, drumstick leaves, pineapples and tomatoes on in vitro coagulation activity. Methods: Aqueous and ethanolic extracts of leaves of Mangifera indica, Moringa oleifera, Vernonia amygdalina, and fruits of Ananas comosus and Solanum lycopersicum were prepared using the cold maceration method and lyophilized. The freeze-dried extracts were prepared into four concentrations. Platelet-poor plasma was obtained from ten healthy volunteers. Prothrombin Time (PT) and activated Partial Thromboplastin Time (aPTT) were determined by visual detection of clot formation. The mean and standard deviation were determined and compared with the controls. Results: PT values for females were higher for aqueous and ethanolic extracts except for A. comosus. Female aPTT values were reduced compared to males except for V. amygdalina. There were no changes in PT and aPTT across the concentration gradient. PT control values significantly differ, however, there were no significant differences in aPTT control values between genders. This study revealed that PT and aPTT values differ significantly between genders. Conclusion: Mangifera indica and M. oleifera have procoagulant activity, A. comosus has anticoagulant activity, while V. amygdalina does not affect coagulation time.
Simultaneous Determination of 2,4-D, Dicamba, and Mecoprop in Soil Leachates by Gas Chromatography with Electron Capture Detection

Field: Chemistry (Physical Sciences)

Abstract Capillary gas chromatography (GC) with electron capture detection (ECD) and mass selective detection (MSD) was used for simultaneous determination of 2,4-dichlorophenoxyacetic acid (2,4-D), 3,6-dichloro-2-methoxybenzoic acid (dicamba), and (±)2-(4-chloro-2-methylphenoxy)propanoicacid (mecoprop) extracted from soil leachates. The 2,2,2-trif luoroethanol (TFE) esters of the acid analytes were synthesized by using H2SO4 as the catalyst. Efficiency of derivatization and instrumental molecular response were compared for herbicides methylated with boron trifluoride-methanol (14%, w/v), H2S04-methanol (33%, v/v), and diazomethane. The molecular integrity of TFE-2,4-D, TFE-dicamba, and TFE-mecoprop in the mixture was confirmed by GC-MSD. The TFE-esterification efficiency was maximized by adjusting the volume of H2SO4, the reaction time, and the reaction temperature. Optimal efficiency for the herbicide mixture was obtained by adding 1 m└ H2SO4 and 1 m└ TFE to the dried extract and allowing the reaction to proceed at 22�C for 8 h or by adding 0.5 m└ H2SO4 and 1 m└ TFE at 60°C for 120 min. Maximum esterification efficiency required an increased temperature and a decreased reaction time. The sensitivity of GC-ECD was about 2-20 times greater in determining TFE esters than in determining methyl ester derivatives. The herbicides were extracted simultaneously from soil leachates previously spiked with the analytes and esterified to TFE derivatives. Herbicide recovery, peak resolution, and detector sensitivity were excellent without column cleanup procedures.
Mitigation of whitefly honeydew levels on cotton lint via thermal and citric acid treatment

Field: Agricultural and Biological Sciences (Life Sciences)

Contamination of cotton lint by insect honeydew can interfere with carding, roving, and spinning processes at the mill, and thus presents a major concern for the textile industry. Several methods exist for the detection of insect honeydew on cotton lint, but there are currently no methods available for the remediation of insect honeydew contamination. The objective of this study was to determine the effectiveness of a heat-activated catalyst in decreasing the honeydew level of a contaminated cotton sample. Cotton lint heavily contaminated with whitefly honeydew was treated with citric acid and subsequently subjected to elevated temperatures for varying periods of time. Sugar concentrations on the cotton lint were analyzed as a function of temperature and heat duration using high-performance anion-exchange chromatography. Levels of honeydew sugars decreased for catalyst-treated cotton compared with untreated cotton when heated at a temperature of 160°C. Chemical treatment of contaminated cotton in conjunction with elevated temperatures may be the basis of a potential method for the mitigation of stickiness on cotton prior to processing at the mill.
X-ray photoelectron spectroscopy study of GaAs(110) cleaved in alcoholic sulfide solutions

Field: Chemistry (Physical Sciences)

X-ray photoelectron spectroscopy has been used to study chemical bonds which appeared on the (110) surface of GaAs after cleavage of the crystal in solutions of sodium sulfide in different alcohols. It has been shown that after such treatment the sulfur atoms are almost exclusively bonded only to gallium atoms. This is conditioned by the electrostatic interaction of sulfur ions in the solution with the surface ions of the crystal lattice of the semiconductor.
Mutual Adversaries, Fellow Dissidents

Field: Arts and Humanities (Social Sciences)

Abstract In mid- to late 20th-century Algeria, the language in which an author wrote reflected more than personal preference: it indicated a political affiliation and a position within the culture wars that merged with the violent conflict of the 1990s. Taking the tension between francophone, arabophone, and pluralist factions in Algerian literature as its point of departure, this article sheds light on the transcendent and multilingual “language” of dissidence exemplified in the novels of al-Ṭāhir Waṭṭār and Tahar Djaout. Previous work on Waṭṭār and Djaout has portrayed their mutual antipathy as an unbridgeable political divide. This article challenges this interpretation through an analysis of Waṭṭār’s novel al-Zilzāl (1974) and Djaout’s posthumous novel Le Dernier Été de la raison (1999). The article concludes that Waṭṭār and Djaout were not simply antagonists. Rather, they were fellow dissidents opposed to a cultural monolith on the one hand, and political and economic malpractice on the other.
The Effect of Sharia Financial Literacy on the Decision of the Use of Service Products in the Sharia Pawn in Yogyakarta

Field: Business, Management and Accounting (Social Sciences)

This study discusses to analyze the influence of Islamic financial literacy on the decision to use Islamic financial product services. The diverse educational backgrounds, ages, and occupations of students make them need literacy guidance to make decisions in choosing sharia pawn products that are suitable for the family’s financial needs. The population in this study is Sharia Pawn in Sariharjo, Yogyakarta. Data in the form of primary data using questionnaires and distributed as many as 111 results. The sampling technique was purposive sampling. This research is a quantitative study with data analysis methods using multiple linear regression. The results showed that Islamic finance affects decisions in the use of service products in Islamic pawn where the coefficient of determination (R2) is 83.4%, which means 83.4% of the variation in the decision to use products in sharia pawn following 3 supporting variables such as Knowledge and Understanding of Managing Finance (X1), Expertise and Skills in Managing Finance (X2), and Beliefs or Belief in Sharia Pawn (X3). While the remaining 16.6% was approved by other variables not approved in this study. Keywords: Sharia Financial Literacy; Sharia Pawn; Customer Decision
One‐week therapy for Helicobacter pylori eradication: ranitidine bismuth citrate plus medium‐dose clarithromycin and either tinidazole or amoxycillin

Field: Medicine (Health Sciences)

Background: One‐week ranitidine bismuth citrate (RBC)‐based triple regimens may be effective for the eradication of Helicobacter pylori . We evaluated the efficacy of two short‐term RBC‐based eradicating therapies including RBC plus medium‐dose clarithromycin and either tinidazole or amoxycillin. Methods: Seventy consecutive patients, who underwent gastroscopy for dyspeptic symptoms and were found to be H. pylori ‐positive, were randomly subdivided into two groups receiving either RBC 400 mg b.d. plus clarithromycin 250 mg t.d.s. and tinidazole 500 mg b.d. (group RBCCT) or RBC 400 mg b.d. plus clarithromycin 250 mg t.d.s. plus amoxycillin 1 g b.d. (group RBCCA). H. pylori status was evaluated by means of histology and rapid urease test at entry, and by 13 C‐urea breath test alone 8 weeks after treatment. Results: Sixty‐nine out of 70 enrolled patients completed the study: 35/35 in group RBCCT and 34/35 in group RBCCA. One patient in group RBCCA was lost to follow‐up. In group RBCCT, at the end of treatment, 32 of 35 patients were H. pylori ‐negative (per protocol analysis 91%, intention‐to‐treat analysis 91%; 95% CI: 77–98%). In group RBCCA, 31 of 34 patients returned H. pylori ‐negative (per protocol 91%; 95% CI: 76–98%, intention‐to‐treat 89%; 95% CI: 73–97%). Slight side‐effects occurred in 3/35 patients (9%) in group RBCCT and in 3/34 (9%) in group RBCCA. Conclusions: One‐week regimens consisting of RBC plus clarithromycin and either tinidazole or amoxycillin, combine high eradication rates with modest side‐effects. No substantial difference was found between the two treatment regimens tested in this trial.
[Osteoarticular tuberculosis].

Field: Medicine (Health Sciences)

As the incidence of tuberculosis in Japan decreases, osteoarticular tuberculosis becomes relatively rare. Therefore, it is often overlooked or misdiagnosed that leads to cryptic aggravation of the disease. On the other hand, because of population aging in Japan, degenerative conditions such as compression vertebral fracture or osteoarthritis should be considered as differential diagnoses of osteoarticular tuberculosis. In addition, we should beware of extra-pulmonary tuberculosis in the patients who undergo biological agent therapy for rheumatoid arthritis that has been advanced drastically in recent years. Surgical treatment for osteoarticular tuberculosis is still an essential part of its treatment in order to achieve early rehabilitation and rapid healing of the lesion.
Knowledge and perceptions of nutrition assistance programmes among young adult students

Field: Social Sciences (Social Sciences)

Abstract The purpose of this qualitative study was to investigate the perceptions of nutrition assistance programmes among young adult students in the United States, and to identify how the current social and political climate, including the COVID‐19 pandemic, has impacted these perceptions and the overall willingness of young adult students to participate in these programmes. Participants were recruited via email and social media to participate in 20‐min virtual, semi‐structured interviews. Twenty‐three participants, between the ages of 18 and 25 years from three states in the United States were interviewed. Ten participants reported having experienced food insecurity (FI) in their lifetime, with 21 participants currently having enough food to eat, while two sometimes did not currently have enough to eat. Seven participants had utilised nutrition programmes in their lifetime. Interviews were video and audio recorded, transcribed, and coded using a six‐step thematic analysis. Young adult students were largely unaware of nutrition assistance programmes and eligibility requirements but still perceived these programmes to be successful, with a higher proportion of the participants who had utilised a nutrition assistance programme in their lifetime expressing the view that they were generally successful compared to those who had never utilised one. Most were cognizant of the social stigma surrounding these programmes yet expressed a willingness to utilise them and reported an increased willingness to utilise nutrition assistance programmes as a result of the COVID‐19 pandemic. COVID‐19 made young adult students aware of FI and the important role nutrition assistance programmes play in our society. Young adult students expressed the belief that the Biden administration will have a positive impact on nutrition assistance programmes but had a general hesitation to discuss politics. The COVID‐19 pandemic has increased young adult students' willingness to utilise nutrition assistance programmes, although, access to these programmes remains low due to a lack of knowledge and general unawareness of programme availability and accessibility. Education is needed to improve overall knowledge of, and facilitate access to, nutrition assistance programmes while combating perceptions around stigma.
An approach for creation and implementation of national cyber security strategy

Field: Computer Science (Physical Sciences)

In this study, it is aimed to demonstrate how to develop a strategy in order to ensure effective cyber security of the assets owned, information and communication systems and infrastructures in cyberspace and to be a powerful force in cyber warfare and deterrence in a country. In this context, an approach is established for the creation and implementation of a national cyber security strategy required related the subject, opinions are revealed and evaluations are made.
Antinuclear antibody-negative systemic lupus erythematosus - how common?

Field: Medicine (Health Sciences)

Dr Stenkvist replies as follows:In relation to Dr Paul Silcocks comments on observer variation I wish to make the following comment:The breast cancer classification systems we analysed not only have a poor reproducibility but they also lack clinical value in that they do not take into account rate of recurrence.However, parameters whose measurement is easily reproducible, such as "tumour markers" (CEA etc), DNA dis-
The combination of gas chromatography and infrared spectroscopy using a flow liquid cell

Field: Chemistry (Physical Sciences)

ガスクロマトグラフィーと赤外吸収スペクトル法の直結化を,新たに考案した共凝縮法により,液体セルを用いて行なった.すなわち,分離管を出たキャリヤーガスに有機溶媒蒸気(四塩化炭素)を混合し,これを小さなリービッヒ型冷却器に導き,キャリヤーガスとともに分離されて溶出する試料成分を有機溶媒蒸気といっしょに凝縮させて液化し,試料中の各成分を溶液の形で連続的に検出用液体セルに流入させ,その赤外吸収スペクトルをくりかえし測定する方法である.赤外分光光度計の透過率変化は電子管式平衡記録計で記録した.測定方法は一定波数領域走査,またはいくつかの波数領域の組み合わせをくりかえし連続的に走査して行なった.試料としてはベンゼン,オクタン,メチルイソブチルケトン,ピロール,デカンなどを用いた.提案した方法はガスセルを用いてのGC-IR法に比べて比較的簡単に両者の直結ができ,良好な結果を与えた.これにより迅速定性・定量分析が可能であることを見いだした.
N-Acetylcysteine Improves Acrylamide-Induced Changes in Ovarian Tissue and Serum Levels of Pituitary-Ovarian Axis Hormones in Adult Rats

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective: The purpose of this study was to evaluate the protective effect of N-acetylcystein (NAC) on ovarian tissue and serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol, and progesterone in Acrylamide (AA)treated adult rats. Materials and Methods: Forty-two adult female Wistar rats were randomly assigned into 7 groups of 6 including: a control group without treatment, a placebo group received distilled water intraperitoneally, an AA group received 50 mg/kg by oral gavage, a NAC group received 40 mg/kg intraperitoneally, an AA+NAC10, AA+NAC20 and an AA+NAC40 groups received 10, 20 and 40 mg/kg of NAC intraperitoneally, respectively and then also received 50 mg/kg AA by oral gavage for 28 days. Serum levels of FSH, LH, estradiol and progesterone were measured by radioimmunoassay method and ovarian tissue was evaluated histopathologically. Results: Administrating AA alone decreased the number of ovarian follicles, corpus luteum and the levels of FSH, estradiol and progesterone, while increased the number of atretic follicles and LH level compared to the control, placebo and NAC groups (p&amp;lt;0.05). The administration of NAC alone had no effect on the number of ovarian follicles, corpus luteum and the level of hormones compared to the control and placebo groups (p&amp;gt;0.05). Following AA+NAC20 and AA+NAC40 administration and not AA+NAC10, the number of ovarian follicles, corpus luteum and also the levels of FSH, estradiol and progesterone increased, while the number of atretic follicles and LH level decreased (p&amp;lt;0.05), which was in a dose-dependent manner compared to the AA group. Conclusion: NAC could recover the AA female rat reproductive toxicity in a dose-dependent manner, and improved folliculogenesis.&amp;nbsp;
A pattern mining approach toward discovering generalized sequence signatures

Field: Computer Science (Physical Sciences)

Typically, sequence signatures, such as motifs and domains, are assumed to be localized in one region of a sequence or are derived as combinations of the former. We generalize the concept of sequence signatures and introduce an algorithm for efficiently determining signatures based on subsequences that may be located anywhere on a sequence. In a preprocessing step, sequences are transformed into a feature space that is subsequently used to mine generalized signatures. We evaluate our signatures in relation to those in the InterPro database and highlight the differences between them. A second comparison with InterPro shows that our signatures can be used to derive sequence annotations with a higher
Navigated percutaneous screw fixation of the pelvis with O-arm 2: two years’ experience

Field: Medicine (Health Sciences)

&lt;p&gt;&lt;strong&gt;Aim &lt;br /&gt;&lt;/strong&gt;To evaluate the case series of the patients operated with percutaneous fixation by the navigation system based on 3D fluoroscopic images, to assess the precision of a surgical implant and functional outcome of patients.&lt;br /&gt;&lt;strong&gt;Methods &lt;br /&gt;&lt;/strong&gt;A retrospective study of pelvic ring fractures in a 2-year period included those treated with the use of the O-Arm 2 in combination with the Stealth Station 8. Pelvic fractures were classified according to the Tile and the Young-Burgess classification. All patients were examined before surgery, with X-rays and CT scans, and three days after surgery with additional CT scan. The positioning of the screws was evaluated according to the Smith score, the outcome with the SF-36.&lt;br /&gt;&lt;strong&gt;Results&lt;/strong&gt; &lt;br /&gt;Among 24 patients 18 were with B and six with C type fracture according to Tile, while eight were with APC, 10 LC, and&lt;br /&gt;six with VS type according to Young-Burgess classification. All patients were treated in the supine position, except two. A total of 41 iliosacral or transsacral screws and five anterior pelvic ring screws were implanted. The medium surgical time per screw was 41 minutes. There was a perfect correspondence of screw scores value from post-operative CT and intraoperative fluoroscopy. The mean screw score value was 0.92. There were no cases of poor positioning. The median follow-up was 17.5 months. The patients were satisfied with their health condition on SF-36.&lt;br /&gt;&lt;strong&gt;Conclusion &lt;/strong&gt;&lt;br /&gt;The use of the O-arm guarantees great precision in the positioning of the screws and reduced surgical times with excellent&lt;br /&gt;clinical results in patients.&lt;/p&gt;
Appraisal of recent work on role of crystallography in ferrous and non-ferrous pearlite

Field: Materials Science (Physical Sciences)

Work on pearlite up to 1962 is briefly outlined and work on the crystallography of pearlite before 1984 is discussed. Studies of the heterophase boundaries in ferrous and non1errous pearlite by transmission electron microscopy over the past decade are introduced. The ‘ledge growth mechanism’ based on such studies is evaluated against the ‘classic’ view of pearlite growth. It is concluded that the hypothesis of the ledge growth mechanism offers a comprehensive explanation of pearlite phenomena and that the classic view fails to account for some features of pearlite. The implications of the new research on pearlite are addressed. The details of ledge motion and the velocity–spacing problem are discussed. The lack of work on the importance of crystallography on morphological evolution of pear lites is identified. Further work necessary to evaluate and advance the new understanding of pearlite is outlined.MST/3253
The Usefulness of In Vitro Interferon-γ Assay for Differential Diagnosis between Intestinal Tuberculosis and Crohn's Disease

Field: Medicine (Health Sciences)

When differential diagnosis between ITB and CD is difficult, T-SPOT.TB blood test may be a helpful and rapid diagnostic tool to exclude ITB. Prospective large-scaled studies are required for further evaluation of the usefulness of T-SPOT.TB blood test for differential diagnosis between ITB and CD.
Structure and chemistry of antibiotic LL-Z1271.alpha., an antifungal carbon-17 terpene

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure and chemistry of antibiotic LL-Z1271.alpha., an antifungal carbon-17 terpeneGeorge A. Ellestad, Ralph H. Evans Jr., Martin P. Kunstmann, John E. Lancaster, and George O. MortonCite this: J. Am. Chem. Soc. 1970, 92, 18, 5483–5489Publication Date (Print):September 1, 1970Publication History Published online1 May 2002Published inissue 1 September 1970https://pubs.acs.org/doi/10.1021/ja00721a031https://doi.org/10.1021/ja00721a031research-articleACS PublicationsRequest reuse permissionsArticle Views190Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts