jimnoneill/paper-to-field-training huggingface dataset:
Study of Serum Dickkopf-1, and Golgi Membrane Protein in Egyptian Patients with Colorectal Cancer

Field: Medicine (Health Sciences)

Background: Colorectal cancer is considered as a major cause of morbidity and mortality throughout the world. Colonoscopy is highly sensitive and specific for detection of lesions. It is likely that the combination of screening methods is more effective than the use of any method alone. Serum Dickkopf-1 (DKK1) and Golgi membrane protein (GP73) has emerged as a promising biomarker for colorectal cancer diagnosis. However, their diagnostic accuracy is quite variable Aim of the work: to study serum Dickkopf-1, and Golgi membrane protein in Egyptian patients with colorectal cancer as well as their correlation to CEA, CA 19-9 & other -biochemical parameters and determine the possibility to use them as a diagnostic tool for colorectal cancer. Patients and methods: This study included 30 patients divided into 2 groups: group I: comprised 15 patients with CRC, group II: comprised 15 patients with other colorectal disease together with 15 healthy control. The diagnosis was established on the basis of history, clinical, laboratory, endoscopic and histological data. CBC, ESR, liver, kidney function tests, CEA, CA 19-9, were also done. Results: There was highly significant increase in DKK1 in group I, II in comparison to control group with no significant difference between group I, group II and no significant difference in GP73 between the studied groups. There was highly significant decrease in Hg& increase in ESR level in GI in comparison to control group while no significant difference in WBCs was detected among the studied groups. In GI there were significant positive correlations between GP73 levels, Hg, RBCs, ESR while in GII a significant positive correlation between GP73 levels & CA19-9 and between DKK1& CEA was found. Conclusions: DKK1 is involved in the pathogenesis of colorectal diseases including colorectal cancer but the exact value of serum DKK1 & GP73 as a diagnostic tool for colorectal cancer requires additional investigation.
BELLA NOTTE

Field: Arts and Humanities (Social Sciences)

Performer: THE PAESANOS; MITCHELL MILLER AND ORCHESTRA Writer: Lee; Burke From Walt Disney's LADY AND THE TRAMP. Digitized at 78 revolutions per minute. Four stylii were used to transfer this record. They are 2.0mil CT, 2.3mil CT, 2.8mil CT, 3.3mil CT. These were recorded flat and then also equalized with Turnover: 400, Rolloff: -12. The preferred versions suggested by an audio engineer at George Blood, L.P. have been copied to have the more friendly filenames. Matrix number: D214B Catalog number: D214B
Fads, Distance Education, and the Importance of Theory

Field: Arts and Humanities (Social Sciences)

Abstract Fads are common in every area of education. The problem with fads is that even promising developments are quickly abandoned to make room for the next innovation. Educational innovations become fads partly because they are without a firm foundation in theories of learning, or because that foundation is not fully identified and communicated. There have been many examples of fads in information technology in education. The question of whether or not distance education will turn out to be a fad is addressed, and some tentative steps are discussed that might help avoid its achieving fad status.
An improvement in the approximation of basic curve μ=μ(h) using spline functions

Field: Mathematics (Physical Sciences)

This paper deals with a very efficient method in building the magnetic permeability curve using the cubic spline function C(2). We first approximate the basic curve of magnetization B = B(H) using spline function [1] and [3]. From this function we can find the first derivatives analytically. It is also possible to determine the maximum value of magnetic permeability [2]. Having all necessary information about B = B(H) and μmax we can deduce the derivative curve namely B' = B'(H) and also obtain the first derivative at the beginning and at the end of the curve μ = μ(H).
STUDY OF ANTIFUNGAL ACTIVITY OF Bacilli SPECIES CULTURED ON AGRO-INDUSTRIAL WASTES

Field: Agricultural and Biological Sciences (Life Sciences)

The three Bacillus species isolated from petroleum refinery waste were examined for antifungal activity on brewery effluents and molasses for biotechnological applications. Bacillus strains were identified by three different methods: 16S rRNA gene sequences, BIOLOG system and fatty acid analysis (FAME). The results demonstrated the ability of all three Bacillus strains cultured on brewery effluents and molasses to inhibit mycelial growth of the 10 tested fungi to varying degrees measured by agar plate inhibition assays. Fungi inhibited to the greatest degree as measured by the zones of inhibition were Botrytis cinerea A 258, Phomopsis viticola W 977, Septoria carvi K 2082, Colletotrichum gloeosporioides A 259, Phoma complanata A 233 and Phoma exigua var. exigua A 175. It was also observed that the fungal mycelial growth was inhibited by the cell-free supernatants, indicating lipoprotein-like activity of antifungal agents (mainly biosurfactants). Tested fungi were most sensitive to the Bacilli supernatants obtained from the molasses cultures including: B. cinerea A 258, R. solani W 70, S. sclerotiorum K 2291, Phomopsis diachenii K 657, C. dematium K 425, P. complanata A 233, P. exigua var. exigua A 175. In the previous study it was shown that Bacillus species produced biosurfactants. Application of natural products such as these Bacillus species or their byproducts may be a new approach to phytopathogen control therefore reducing the need for fungicides.
Requirement of the Inositol Trisphosphate Receptor for Activation of Store-Operated Ca 2+ Channels

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The coupling mechanism between endoplasmic reticulum (ER) calcium ion (Ca 2+ ) stores and plasma membrane (PM) store-operated channels (SOCs) is crucial to Ca 2+ signaling but has eluded detection. SOCs may be functionally related to the TRP family of receptor-operated channels. Direct comparison of endogenous SOCs with stably expressed TRP3 channels in human embryonic kidney (HEK293) cells revealed that TRP3 channels differ in being store independent. However, condensed cortical F-actin prevented activation of both SOC and TRP3 channels, which suggests that ER-PM interactions underlie coupling of both channels. A cell-permeant inhibitor of inositol trisphosphate receptor (InsP 3 R) function, 2-aminoethoxydiphenyl borate, prevented both receptor-induced TRP3 activation and store-induced SOC activation. It is concluded that InsP 3 Rs mediate both SOC and TRP channel opening and that the InsP 3 R is essential for maintaining coupling between store emptying and physiological activation of SOCs.
Symmetry as a foundational concept in Quantum Mechanics

Field: Physics and Astronomy (Physical Sciences)

Symmetries are widely used in modeling quantum systems but they do not\ncontribute in postulates of quantum mechanics. Here we argue that logical,\nmathematical, and observational evidence require that symmetry should be\nconsidered as a fundamental concept in the construction of physical systems.\nBased on this idea, we propose a series of postulates for describing quantum\nsystems, and establish their relation and correspondence with axioms of\nstandard quantum mechanics. Through some examples we show that this\nreformulation helps better understand some of ambiguities of standard\ndescription. Nonetheless its application is not limited to explaining confusing\nconcept and it may be a necessary step toward a consistent model of quantum\ncosmology and gravity.\n
Cystitis and urolithiasis patients presenting with prostate abscess in a dog

Field: Veterinary (Health Sciences)

Prostatic abscess could be result of chronic prostatitis but also it has been shown as a cause of prostatitis. In this case, treatment process was evaluated in 11 years old pointer breed dog which was presented to Department of Internal Medicine Clinic, Faculty of Veterinary Medicine, Ondokuz Mayıs University, with difficult urination problem. Prostatic abscess, Bening Prostatic Hyperplazia (BPH) and recurrent cystitis condition were identified with ultrasonographic examination in the dog. A successful result were obtained against cystitis and prostatic abscess with long term antibiotic usage (Enrofloxacin 5mg/kg, BID), prescription diet (Canine s/d, Canine s/o) and vitamin C treatment.
Crafting a Credible Black Self in African American Life Writing

Field: Arts and Humanities (Social Sciences)

Moody’s introduction observes that works of African American autobiography predate even the oft-cited 1760 Narrative of the Uncommon Sufferings, and Surprizing Deliverance of Briton Hammon, and the 1783 petition to the Commonwealth of Massachusetts filed by Belinda Royall (Sutton). Moody argues the genre of Black life writing has persistently appealed to African American authors telling life stories in promoting diverse causes from a range of African-descended ethnic backgrounds. She contends that the financial rewards of Michelle Obama’s memoir Becoming — and the testimonies it has generated — reveal African American readers look to each other for life narratives of diverse Black experiences that enable the construction, constitution, and promulgation of a credible Black self. Moreover, Moody asserts, the persistent cultural shifts of African American life writing as literary and historical phenomena have been well documented. Joining a long trajectory of critical studies, the introduction establishes the prominence of Black life writing across US history.
Complex Management of Bilateral Congenital Hydronephrosis in a Pediatric Patient: A Multidisciplinary Approach

Field: Medicine (Health Sciences)

Congenital anomalies of the kidney and urinary tract (CAKUT) are common developmental malformations and a leading cause of pediatric renal dysfunction. Severe hydronephrosis, especially when accompanied by ureteral duplication, ureterocele, or neurogenic bladder, poses significant diagnostic and therapeutic challenges. This case report presents a 7-year-old male with prenatally diagnosed bilateral grade IV/V hydronephrosis (according to the radiology hydronephrosis grading system), complicated by the right pyeloureteral duplication, the left ureterocele, and the neurogenic bladder. The patient’s clinical course was marked by recurrent urinary tract infections (UTIs), progressive renal dysfunction, and multiple surgical interventions. Initial decompression via bilateral ureterostomy and stenting led to significant improvements in renal function. However, the patient experienced recurrent febrile UTIs caused by multidrug-resistant pathogens, necessitating repeated hospitalizations and intravenous antibiotic therapy. Serial imaging studies documented persistent hydronephrosis, a neurogenic bladder, and vesicoureteral reflux. Subsequent surgical interventions included bilateral ureteral reimplantation, excision of the left ureterocele, and removal of a fibroepithelial polyp from the bladder wall. Despite these interventions, residual left hydronephrosis and right kidney hypoplasia persisted, underscoring the need for long-term surveillance. This case highlights the diagnostic and therapeutic challenges of managing CAKUT and emphasizes the importance of a multidisciplinary approach integrating imaging, functional assessment, and surgical planning. Early diagnosis and timely intervention can stabilize renal function, but ongoing monitoring and individualized treatment remain crucial for optimizing long-term outcomes in children with complex CAKUT.
Towards Test-Driven Development for FPGA-Based Modules Across Abstraction Levels

Field: Computer Science (Physical Sciences)

High-Level Synthesis (HLS) tools help engineers to deal with the complexity of building heterogeneous embedded systems that make it use of reconfigurable technology. Also, HLS opens up a way for introducing, into the development flow of custom hardware components, techniques well known in the software industry such as Test-Driven Development (TDD). However, the support provided by HLS tools for verification activities is limited, and it is usually focused on the initial steps of the design process. In this paper, a hardware testing framework is introduced as an enabler for effortless on-board verification of components by applying the Unit Testing Paradigm and, hence, realizing TDD on reconfigurable hardware. The proposed solution comprises a hardware/software introspection infrastructure to verify modules of a system at different stages, spawning multiple abstraction levels without extra effort nor redesigning the component. Our solution has been implemented for the Xilinx ZynQ FPGA-SoC architecture and applied to the verification of C-kernels within the CHStone Benchmark. Effortless integration into the Xilinx Vivado design flow and tools is supported by a set of automatic generation scripts developed for this end. Experimental results show a considerable speedup of the verification time and unveils inaccuracies concerning the co-simulation estimation obtained by Xilinx tools when compared with the on-board latency measured by our framework.
Abiotic factors and photosynthetically active photon density affect the physiological mechanisms of jaboticaba

Field: Agricultural and Biological Sciences (Life Sciences)

ABSTRACT In fruit species, the amount of solar energy absorbed can influence fruit quality; hence, ensuring optimal light distribution management in the canopy of plants is essential. Therefore, the objectives of this study were (i) to analyze the variations in gas exchange through the day and (ii) identify the photosynthetically active photon flux density (PPFD) that promotes higher chlorophyll fluorescence and electron transport rate in jaboticaba seedlings. The experimental design was completely randomized, with treatments consisting of 18 photosynthetic photon flux densities and three evaluations throughout the day. Six replicates were used, with two plants per plot. Gas exchange and chlorophyll a fluorescence in P. peruviana were altered due to fluctuating photosynthetic photon flux density (0; 25; 50; 75; 100; 125; 150; 175; 200; 400; 600; 800; 1,000; 1,200; 1,400; 1,600; 1,800; and 2,000 μmol m-2 s-1) and environmental conditions throughout the day (8:00 a.m., 12:00 and 4:00 p.m.). The higher PPFD (1,384.6 μmol m-2 s-1) and air temperature (39.74 °C) at noon (12:00 p.m.) favored gas exchange in this species. An increase in PPFD of up to 1,000 μmol m-2 s-1 positively influenced the gas exchange and chlorophyll a fluorescence of P. peruviana.
1 Title: Genetic Markers for Western Corn Rootworm Resistance to Bt Toxin

Field: Agricultural and Biological Sciences (Life Sciences)

Western corn rootworm (WCR) is a major maize (Zea mays L.) pest leading to annual economic losses of more than $1B in the US. Transgenic maize expressing insecticidal toxins derived from the bacterium Bacillus thuringiensis (Bt) are widely used for management of WCR. However, cultivation of Bt-expressing maize places intense selection pressure on pest populations to evolve resistance. Instances of resistance to Bt toxins have been reported in WCR. Developing genetic markers for resistance will help in characterizing the extent of existing issues, predicting where future field failures may occur, improving insect resistance management (IRM) strategies, and in designing and sustainably implementing forthcoming WCR control products. Here we discover and validate genetic markers in WCR that are associated with resistance to the Cry3Bb1 Bt toxin. A field-derived WCR population known to be resistant to the Cry3Bb1 Bt toxin was used to generate a genetic map and to identify a genomic region associated with Cry3Bb1 resistance. Our results indicate that resistance is inherited in a nearly recessive manner and associated with a single autosomal linkage group. Markers tightly linked with resistance were validated using WCR populations collected from Cry3Bb1 maize fields
Interests and meanings: the socio-technical process of application of biotechnology to crop improvement in India

Field: Social Sciences (Social Sciences)

In India, controversies over genetic engineering technology have become sharper even as attempts are being made to allow field trials and commercial release of some GM crops. By drawing up on insights from sociology of science, the paper argues that production of knowledge and its application through institutional arrangements in the case of genetic engineering is a socio-technical process that involves a complex interplay of conflicting interests and systems of meaning. The paper argues that resolution of the conflicts over interests and meanings by involving all stakeholders is a precondition for continuation of research and utilisation of the output of research by the farming communities.
Equine grass sickness

Field: Veterinary (Health Sciences)

EQUINE grass sickness (dysautonomia) is a neurological disease associated primarily with degeneration of neurons in the autonomic nervous system (including the enteric nervous system), although involvement of the somatic nervous system has also been widely reported. It affects all Equidae, is usually fatal and has an approximate incidence of 1 per cent in some parts of the UK. This article discusses the clinical aspects of the disease and summarises the findings of recent research into the aetiology and epidemiology of the condition.
Developing supply chain integration in the building technologies cluster

Field: Business, Management and Accounting (Social Sciences)

Website: www.mit.wlv.ac.ukBuilding technologies cluster covers a wide range of materials, products, systems and specialist services supplied by a variety of industry sectors. The supply chain of the building technologies industry within the cluster is currently organized on a fragmented basis. However, instead of treating the steps of the supply chain as individual links, building technologies organizations need to transform their supply chain into more synthesized entities through interorganizational connectivity with established integrated architecture. Supply chain integration is generally associated with inter-organizational communications, leading to time compression in processes, services and information flows. The fusion of building technologies design, manufacture, deployment in a building projects and building processes management with Information and Communication Technology (ICT) is seen as forming the core of a strategic vision for supply chain integration for the building technologies industry. This paper presents an incitement into the building technologies cluster by developing a framework for a web-based e-supply chain information system. The intent with the proposed system is to deal with the management and transaction of information across network of supply chain partners. It is targeted towards achieving the integrated supply chain working for the integrated project team through an electronic marketplace.
Exhausted by Social Distancing at Work: Understanding the Effects of COVID-19 Pandemic in Workgroups

Field: Psychology (Social Sciences)

In the new post COVID-19 work order, we propose a multi-level model of how individual level social distancing interacts with workgroup level socio-structural support to influence employee exhaustion and performance. Drawing upon job demands-resources (JD-R) theory, we assert that workplace social distancing presents new job demands that emotionally exhaust employees and hinder their task and change-oriented performance. We further assert that job resources in the form of workgroup task interdependence and support for innovation mitigate these negative effects of social distancing. Per our expectations, multi-level modeling using time-lagged multi-source data from 231 employees and 34 managers revealed a significant relationship between social distancing and employee performance via emotional exhaustion. Further, the positive relationship between social distancing and emotional exhaustion was attenuated by workgroup task interdependence and support for innovation. Finally, moderated mediation path analyses showed that the indirect negative effect of social distancing on employee performance was weaker in workgroups with high task interdependence and high support for innovation.
On the Vortex Sound from Rotating Rods

Field: Engineering (Physical Sciences)

The motion of different bodies imersed in liquid or gaseous media is accompanied by characteristic sound which is excited by the formation of unstable surfaces of separation behind the body, usually disintegrating into a system of discrete vortices(such as the Karman vortex street due to the flow about an infintely long rod, etc.).In the noise from fans,pumps,and similar machtnery, vortexnQif3eI?Yequently predominates. The purpose of this work is to elucidate certain questions of the dependence ofthis sound upon the aerodynamic parameters and the tip speed of the rotating rods,or blades. Although scme material is given below,insufficientto calculate the first rough approximation to the solution of this question,such as the mechanics of vortex formation,never the less certain conclusions maybe found of practical application for the reduction of noise from rotating blades.
Word2Vec Word Embedding-Based Artificial Intelligence Model in the Triage of Patients with Suspected Diagnosis of Major Ischemic Stroke: A Feasibility Study

Field: Medicine (Health Sciences)

Abstract Introduction The possible benefits of using semantic language models in the early diagnosis of major ischemic stroke (MIS) based on artificial intelligence (AI) are still underestimated.The present study strives to assay the feasibility of the Word2Vec word embedding-based AI model in decreasing the risk of false-negatives during the triage of patients with suspected MIS in the emergency department (ED). Methods The main ICD-9 codes related to MIS were used for a 7-years retrospective data collection of patients managed at the ED with a suspected diagnosis of stroke. Data underwent “tokenization” and “lemmatization”. Word2Vec word embedding AI algorithm was used for text data vectorization and a batch strategy was adopted for model training.The false-negatives were rated from the incorrect attribution of the low-intensity code to patients later diagnosed with MIS. Results Out of 649 MIS, the Word2Vec AI algorithm allowed successfully identify 87.69% of them through the recognition of 15 top words, with an area under the curve of 97.2%. The rate of false-negatives related to the implementation of AI model was 0%. Conclusions Word2Vec word embedding-based AI model is reliable and effective in decreasing the risk of false negatives of MIS during patients’ triage in the ED. Further studies on larger cohorts are required to validate the model.
Dynamic Analysis of the Superstructure-Pile Foundation-Soil Interaction System under Earthquake Based on Fuzzy Theory

Field: Engineering (Physical Sciences)

Based on frequency domain method, the seismic responses of the superstructure-pile foundation-soil system are studied taking the dynamic soil-structure interaction into consideration. For analyzing the earthquake response of cylindrical pile foundation, earthquake response analysis of three-dimensional system of pile foundation-soil-superstructure simplify two-dimensional question. The dynamic responses of the interaction system under EI-Centro ground motion excitation are evaluated by using secondary development of the large general finite analysis software Abaqus. It is shown that pile foundation is more anti-seismic and that pile foundation flexibility can improve the structural basic cycle. Based on a comprehensive assessment theory, soil-superstructure interaction problem under Earthquake is analyzed by second-level evaluation of comprehensive evaluation. By applying comprehensive evaluation method fuzzy theory model of soil-superstructure interaction is built. It is show that fuzzy mathematics method is appropriate for this kind of soil-superstructure interaction problem.