jimnoneill/paper-to-field-training huggingface dataset:
Modification by a latent contaminant of glomerular pathology in mice infected with Plasmodium berghei.

Field: Medicine (Health Sciences)

This study was designed to determine, by means of electron microscopy, the effect of latent contaminants-which are associated with the syringe passage of the parasite-on the findings in the glomeruli of P. berghei-infected mice. A rapid alteration of the glomerular basement membrane was observed in mice infected with the syringe-transmitted N strain, but not in those infected with the cyclically passaged Nig strain. Glomerular changes were also seen in mice inoculated with nonparasitized blood from normal mice, obtained after 16 passages by syringe. It appears that these changes were provoked by a latent contaminant that had proliferated after passages of the parasite through mice, and that they constitute a secondary immune reaction.
Thiol-Functionalized Cellulose-Grafted Copper Oxide Nanoparticles for the Therapy of Experimental Colitis in Swiss Albino Mice

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Ulcerative colitis (UC) is a chronic inflammatory disease, which deleteriously affects the lower end of the gastrointestinal tract, i.e., the colon and the rectum. UC affects colonic inflammatory homeostasis and disrupts intestinal barrier functions. Intestinal tissue damage activates the immune system and collectively worsens the disease condition via the production of various cytokines. Ongoing therapeutics of UC have marked limitations like rapid clearance, extensive first-pass metabolism, poor drug absorption, very low solubility, bioavailability, etc. Because of these restrictions, the management of UC demands a rational approach that selectively delivers the drug at the site of action to overcome the therapeutic limiting factors. Metallic nanoparticles (NPs) have good therapeutic efficacy against colitis, but their uses are limited due to adverse effects on the biological system. In this study, we have used biocompatible thiol-functionalized cellulose-grafted copper oxide nanoparticles (C-CuI/IIO NPs) to treat UC. The metal NPs alleviated the colitis condition as evidenced by the colon length and observed physical parameters. Analysis of histopathology demonstrated the recovery of the colon architecture damaged by dextran sulfate sodium-induced colitis. Treatment with C-CuI/IIO NPs reduced the disintegration of goblet cells and the retainment of sulfomucin. Significant downregulation of inflammatory markers like MPO activity, as well as levels of nitrite and TNF-α, was found following C-CuI/IIO NP treatment. The observations from the study suggested that intrarectal treatment of colitis with cellulose-based C-CuI/IIO NPs successfully combated the intestinal inflammatory condition.
OP09.08: 3D neurosonography in fetal syndromes associated with brain abnormalities

Field: Medicine (Health Sciences)

Several syndromes show moderate or severe brain abnormalities. The aim of the present study was to demonstrate the different brain abnormalities in 10 different syndromes by use of 3D ultrasound. Within the last 5 years the brains of 34 fetuses with later on proven syndromes were examined with 3D ultrasound. All scans were performed using E8/E10 GE equipment (Zipf, Austria) with a 5-8 MHz 3D abdominal or 5-9 MHz transvaginal transducer. Gestational age was between 13+0 and 37+0 weeks of gestation. All 34 fetuses showed two or more abnormalities. The brain abnormalities detected with 3D ultrasound were dilatation (n=7) or abnormal shape (n=3) of the brain ventricles, single ventricle (n=6), absent septum pellucidum (n=2), choroid plexus cysts (n=8), abnormal cerebellum (n=6), abnormal gyration (n=8), agenesis (n=4) and partial agenesis (n=1) of the corpus callosum and encephalocele (n=2). The syndromes diagnosed were Apert syndrome (n=2), Smith-Lemli-Opitz syndrome (n=2), De Grouchy syndrome (n=1), De Morsier syndrome (n=2), Miller-Dieker syndrome (n=3), Walker-Warburg syndrome (n=4), Dandy-Walker syndrome (n=5), Aicardi syndrome (n=3), Patau syndrome (n=4) and Edwards syndrome (n=8). 3D neurosonography enables a precise assessment of the fetal brain. Once the volume of the brain is stored in the memory, the brain can be aligned into a correct upright position, allowing an exact comparison of the left and right brain hemisphere. The different visualisation modes of 3D ultrasound enable the operator to demonstrate anomalies of the fetal brain in all three dimensions and in surface images of specific sectional planes. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
The Transformation of Enterprise Productive Way in Economic Globalization

Field: Business, Management and Accounting (Social Sciences)

Through analyzing the production way of two world Factory:USA and Japan,the paper discusses the advantages and disadvantages of both massive production and massive production made to order,and makes proposal on the transformation of production way from massive production to massive production made to order.At the same time,the paper talks on advantages and disadvantages of China becoming a world factory,and makes suggestions on China's enterprises development strategy in the process of economic globalization.
Impacts of cacao agroforestry systems on climate change, soil conservation, and water resources: a review

Field: Environmental Science (Physical Sciences)

Abstract Agroforestry is crucial for improving water quality deteriorated by anthropogenic activities due to the use of chemical substances, including nitrogen (N) and phosphorous (P) in modern agricultural practices (MAPs). This state-of-the-art review aims to revise the influence of agroforestry systems (AFS) on climate change, soil conservation, and groundwater quality. The novelty of this review is that AFS can improve water quality, reduce nutrient loss, and support the biological, chemical, and physical properties of the soil. It is worth noting that the surficial geologic controls, slope gradient, soil types, and topographical conditions are factors that alter a watershed dominated by agroforestry areas. In addition, anthropic aspects, including agricultural practices, can also cause loss of water quality in basins dominated by an AFS area. This review is also novel in that it outlines how AFS can be used for the phytoremediation of contaminated soils to reduce aluminum (Al), mercury (Hg), and cadmium (Cd), among others. Therefore, AFS can be used for water decontamination, climate change mitigation, climate adaptation, and soil conservation. Further research is required to investigate the contribution of AFS to soil integrity.
Enterochromaffin cells in the gut: a distant regulator of brain function?

Field: Neuroscience (Life Sciences)

We read with great interest the recent excellent work by Stevens et al ,1 in which the authors showed that zonulin and fatty acid-binding protein 2 have a relationship with the increase in lipopolysaccharide (LPS) and abnormal composition of gut microbiota in patients with anxiety or depression. We appreciate these findings and would like to discuss the role of enterochromaffin cells (ECs) in brain function in this context.

Accumulating evidence has shown that neuropsychiatric diseases are frequently associated with gut microbiota disorders.2 It has been widely recognised that toxins within the human body mainly stem from the gut.3 The opening of intercellular tight junctions in the gut allow many toxins into the bloodstream that then have a deleterious effect on the brain, finally resulting in a series of neuropsychiatric symptoms. …
[The application of bioinformatics in the research of alternative splicing].

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Alternative splicing, a fundamental and important regulatory mechanism in eukaryotes, allows one pre-mRNA to be processed into many different mature forms within a cell, each of which can have distinct functions. As alternative splicing is associated with human diseases, the study of alternative splicing becomes quite important. Bioinformatics is a new subject for the study of alternative splicing, especially for its regulatory mechanism, prediction and origin. Of course, bioinformatics must be combined with experimental research so as to clarify these aspects of alternative splicing. This paper reviewed the recent research progress in this field in the hope to gain a deeper understanding of eukaryotic gene expression regulation.
Movement Training for the Modern Actor

Field: Arts and Humanities (Social Sciences)

This book is the first critical analysis of the key principles and practices informing the movement training of actors in the modern era. Focusing on the cultural history of modern movement training for actors, Evans traces the development of the ‘neutral’ body as a significant area of practice within drama school training and the relationship between movement pedagogy and the operation of discipline and power in shaping the professional identity of the actor. The volume looks in detail at the influence of the leading figures in movement training — Laban, Alexander, Copeau and Lecoq — on twentieth century professional actor training, and is informed by interviews with students and staff at leading English drama schools. Mark Evans re-evaluates the significance of movement training in the professional drama school, offering a new understanding of the body as a site for performative resistance to industrialization. Despite the publication of a number of ‘how to’ books on movement training for the professional acting student, this is the first text to look behind the curtain and write the unseen biography of the actor’s body.
Supplementary Figure 6 from Critical Roles of Mucin 1 Glycosylation by Transactivated Polypeptide <i>N</i>-Acetylgalactosaminyltransferase 6 in Mammary Carcinogenesis

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Supplementary Figure 6 from Critical Roles of Mucin 1 Glycosylation by Transactivated Polypeptide <i>N</i>-Acetylgalactosaminyltransferase 6 in Mammary Carcinogenesis
Chi-Sim: A New Similarity Measure for the Co-clustering Task

Field: Computer Science (Physical Sciences)

Co-clustering has been widely studied in recent years. Exploiting the duality between objects and features efficiently helps in better clustering both objects and features. In contrast with current co-clustering algorithms that focus on directly finding some patterns in the data matrix, in this paper we define a (co-)similarity measure, named χ-Sim, which iteratively computes the similarity between objects and their features. Thus, it becomes possible to use any clustering methods (k-means, ⋯) to co-cluster data. The experiments show that our algorithm not only outperforms the classical similarity measure but also outperforms some co-clustering algorithms on the document-clustering task.
Tubulin Tyrosine Ligase Like 12 Promoted the Growth of Hep-2 Cells by Interfering with Nitrotyrosine

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Nitrotyrosine,a structural analogue of tyrosine,is present in cells in pathological conditions and is incorporated on the tubulin,which hampers the normal function of microtubules.Studies regarding the functional aspects of nitrotyrosination in tumor are just a few.In this article,the effects of nitrotyrosine and tubulin tyrosine ligase like 12(TTLL12) on the growth of Hep-2 cells were investigated.Western blotting showed that TTLL12 and α-tubulin nitrotyrosination expression increased in Hep-2 cells,and the concentration of α-tubulin nitrotyrosination increased with the increasing concentration of nitrotyrosine.MTT assay showed that cell growth was inhibited with the increasing concentration of nitrotyrosine;TTLL12 stable overexpression Hep-2 cell line was built.After overexpression and control Hep-2 cells were treated with nitrotyrosine,α-tubulin nitrotyrosination was significantly lower in overexpression cells than control cells;the growth of control cells were significantly inhibited,while no visible change was found in the growth of overexpression cells,there was significant difference(P 0.05) between the growth of two species cells.These data indicated that TTLL12 hampers the combination of nitrotyrosine and tubulin,so that hep-2 cell is able to survive in the presence of nitrotyrosine.The further study of the mechanism of this regulation will help to control tumor growth,and find the new therapeutic target for the treatment of cancer.
Walnut Intake Interventions Targeting Biomarkers of Metabolic Syndrome and Inflammation in Middle-Aged and Older Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Field: Medicine (Health Sciences)

Biomarkers of metabolic syndrome and inflammation are pathophysiological predictors and factors of senescence and age-related diseases. Recent evidence showed that particular diet components, such as walnuts rich in antioxidant bioactive compounds and with a balanced lipid profile, could have positive outcomes on human health. A systematic search in PubMed, EMBASE, Cochrane Library, Scopus, and ClinicalTrials.gov databases was performed to retrieve randomized controlled trials published from the beginning of each database through November 2021, reporting on the outcomes of walnut consumption over 22 metabolic syndrome and inflammatory markers in middle-aged and older adults. The search strategy rendered 17 studies in the final selection, including 11 crossover and 6 parallel trials. The study revealed that walnut-enriched diets had statistically significant decreasing effects for triglyceride, total cholesterol, and LDL cholesterol concentrations on some inflammatory markers and presented no consequences on anthropometric and glycemic parameters. Although further studies and better-designed ones are needed to strengthen these findings, the results emphasize the benefits of including walnuts in the dietary plans of this age group.
Analysis of spiral cantilever structures for hybrid vibration energy harvesters

Field: Engineering (Physical Sciences)

The recent advancement of low power electronic circuits has boosted the importance of vibration energy as a viable source to power such devices. Vibration energy can be harvested using piezoelectric, electromagnetic, or triboelectric transductions. Piezoelectric energy harvesters typically use micro-scale cantilevered beams, but their fundamental frequency often exceeds the range of most mechanical vibrations. While increasing beam length can reduce the frequency, it may lead to impractical designs. Multi-cantilever beam systems offer an alternative by addressing these limitations while maintaining efficiency. This study explores the significance of various orthogonal spiral cantilevers as prominent structures for the design of a hybrid vibration energy harvesting using the piezoelectric-electromagnetic technique. As piezoelectric requires higher stress density, electromagnetic transduction requires a greater displacement to enhance the power output, the analysis is performed for the natural frequency, stress distribution and surface displacement of various beam structures, ensuring stable and efficient energy harvesting. All the structures are simulated in COMSOL Multiphysics and excited with a vibration force of 1g acceleration. Among the analyses on spiral cantilevers, orthogonal spiral cantilevers have shown the best response. The natural frequency of the structures has shown a decreasing trend which varied from 31Hz for structures with the number of beams (n) = 2 to 15.3Hz for structures with n=6. With a displacement of 0.307cms and maximum Von Mises stress of 3.83x106N/m2 orthogonal spiral structure with n=5, has proved to be the ideal candidate for VEH in this study. This study serves as the preliminary analysis for the use of spiral structures as prominent structures for developing VEHs, overcoming traditional limitations, and providing a robust solution for harvesting ambient vibrations.
Give Us This Day Our Daily Bread: The African American Megachurch and Prosperity Theology

Field: Social Sciences (Social Sciences)

This dissertation explores the simultaneous rise of megachurches and Prosperity Theology within the black church. Recognizing that the megachurch and Prosperity Theology represent two separate phenomena within contemporary religion, I also acknowledge the tendency to regard them as being synonymous. My research begins with an examination of the traditional African American church and pastor, and an exploration of the recent growth of megachurches within the black community. In an attempt to better understand the Prosperity Gospel, I evaluated it in comparison to the Social Gospel, discovering the similarities and differences between the two movements. Considering that there is no consensus as to how Prosperity Theology is defined, I examine the various ways in which it has been defined by African American megachurch pastors. In particular, I assess the ways in which Prosperity Theology represents an extension of the traditions of the black church and its emphasis on economic, social, and political empowerment. This dissertation compares the ministries of Dr. Creflo Dollar, Senior Pastor of Atlanta Georgia?s World Changers Church International and Bishop Joseph W. Walker, III, Senior Pastor of Mount Zion Baptist Church in Nashville, Tennessee. Both are regarded as proponents of Prosperity Theology, however, they advance significantly different approaches to prosperity and Prosperity Theology. An examination of the teachings of Dr. Dollar and Bishop Walker indicate that Dr. Dollar?s beliefs put him at odds with many traditionalists in the black church. In contrast, Bishop Walker?s ministry more closely resembles that of a traditional African American church. These findings are further supported by the responses of their churches? members. The research conducted suggests that Prosperity Theology may be useful in facilitating the goals of economic, social, and political empowerment historically advocated by the black church.
THE COMPARISON OF PHYSICAL EDUCATION AND SPORTS TEACHER TRAINING SYSTEMS IN TURKEY AND IRAQ

Field: Social Sciences (Social Sciences)

In this study, it was aimed to reveal the similarities and differences of educations of Physical Education and Sports Teachers in Turkey and Iraq by comparing the conditions to be accepted into university, education process and evaluation systems and develop suggestions accordingly. In the study, the survey model from the qualitative research models was practiced. As for the approach, the horizontal approach from the comparative education approach was utilized. The document review method was applied as the data analysis method. In addition to the web pages from three universities, available articles and books related to the subject of the study were benefited from. As a result of the study, it was determined that several meaningful differences existed in many variables which were compared between the physical education and sports teaching systems in Turkey and Iraq. Within the framework of education of physical education and sports teacher, it was concluded that variables as conditions to be accepted to the faculty, the received education, the contents of the syllabus, education process, and evaluation systems were differentiated between the two countries. It was observed that education systems of each country for physical education and sports teachers were restructured according to their own cultures and social, political and economic conditions. In light of this data, several suggestions were made about the physical education and sports teaching education systems of both of the countries.
Purification and properties of .ALPHA.1- and .ALPHA.2-macroglobulins in the dog.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

1) The ultrafiltration of serum collected from dogs by a filtration film with a pore size of 300, 000, Blue Sepharose CL-6B affinity chromatography and Ultrogel AcA 22gel filtration chromatography eluted a third protein fraction in addition to α1-macroglobulin (α1-M) and α2-macrogrobulin (α2-M). The subsequent use of preparative agarose gel isoelectric focusing with a cover gel facilitated the extraction of pure α1-M and α2-M protein fractions.2) Analytical agarose gel isoelectric focusing and Ferguson plot by agarose gel electrophoresis revealed the following: (1) dog α1-M had an isoelectric point (pI) of 5.4 and a molecular weight of 724, 000; and (2) dog α2-M had a pI of 5.7 and a molecular weight of 758, 000.
Detection of Persisting Influenza Virus with Turkey Trachea Cultures

Field: Veterinary (Health Sciences)

SUMMARY Persisting avian influenza virus could be detected in turkeys beyond the 7th day of infection only by culture of tracheas from infected birds. Virus isolations from tracheal swabs were made from 17 of 27 turkeys on day 3, and 7 of 27 on day 7, with no isolations by swabbing after day 7. Virus was recovered from 5 different birds by tracheal culture on postinfection days 14, 18, 26, and 29.
Study on the Deacidifying Condition of Litchi Wine by Ion-exchange Resin 314

Field: Chemical Engineering (Physical Sciences)

The deacidifying conditions by ion-exchange resin 314 were investigated by orthogonal experiments.The optimal parameters were that the ratio of ion-exchange resin 314 to wine,stirring rate and time were 1:10,200 r/min and 60 min,respectively.It was proved that ion-exchange resin 314 could decrease volatile acid effectively.When the total acid of Litchi wine got the certain concentration,the mass fraction of volatile acid was 0.35 g/L