jimnoneill/paper-to-field-training huggingface dataset:
Comparison between IgE and IgG<sub>4</sub> binding peptides detected by microarray immunoassay for each serum tested. Discrepancies between IgE and IgG4 binding peptides are in bold.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

<p>Comparison between IgE and IgG<sub>4</sub> binding peptides detected by microarray immunoassay for each serum tested. Discrepancies between IgE and IgG4 binding peptides are in bold.</p>
Study on Effects of Protein Modification Reagents on CGTase

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The effects of some protein modification reagents on the activity of cyclodextrin glucanotransferase(CGTase) have been studied. That the enzyme was not affected by DIC, PMSF, DTT and Ch-T modification, suggested that guanido, hydroxyl, disulfide bond and mehionine residues were insignificant to enzyme activity. The enzyme activity was remarkably decreased after DEPC, NBS, EDC modification.The results indicated that carboxyl group, imidazolyl group and indolyl group seemed to be significant to the catalytic activity of cyclodextrin glucantransferase.
The Best Time of their Lives: Researching the History of Prahran Technical School

Field: Arts and Humanities (Social Sciences)

The history of Prahran Technical School is a remarkable story. Created by the Prahran Mechanics’ Institute, the ‘Tech’ opened in High Street in 1915. With both junior and senior sections, a boys’ school and later a girls’ school, it survived for fifty years with barely sufficient funding. Art had always featured as a major stream of study, however, and in the 1960s it became Melbourne’s most innovative art school. In this paper the author shares her experiences of gathering her material and shaping her research.
ChemInform Abstract: Cyclopentane Construction by Rhodium‐Catalyzed Intramolecular C‐H Insertion: Scope and Selectivity

Field: Chemistry (Physical Sciences)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
OPTIMASI PRIMER SINGLE NUCLEOTIDE AMPLIFIED POLYMORPHYSM (SNAP) PADA GEN BRASSINOSTEROID (BRI) KELAPA SAWIT

Field: Agricultural and Biological Sciences (Life Sciences)

Optimisation of Single Nucleotide Amplified Polymorphism (SNAP) Primers in Brassinosteroid (BRI) Gene of Oil PalmÂ Oil palm varieties that have high yields still have a high rate of stem height increase, and it has an impact on difficulties at harvest. Brassinosteroid (BRI) is one of the growth hormones that regulate stem height increase. In this study, the sample used is three types of oil palm, namely E. guineensis which represents the height growth of normal oil palm stems, E. oleifera which represents slow stem height growth, and the result of crossing or hybrid Eo x Eg which is expected to inherit the traits between the two the crossed parent. Sequencing was carried out on samples using a specific primer for the BRI gene that triggers elongation and division of stem cells. The Single Nucleotide Amplified Polymorphisms (SNAP) primers used in the analysis process need to find the optimum temperature to obtain the optimum PCR conditions. Four primers of Single Nucleotide Amplified Polymorphism (SNAP) that get the optimum temperature with a mixture of normal reagents are BRI 69 Alt-Rev and BRI 562 Ref-Rev at 55oC, BRI 1206 Alt-Rev at 57oC and BRI 1206 Ref-Rev at 58oC. Two primers require additional MgCl2 in the reactant mixture, namely BRI 69 Ref-Rev at 55oC and BRI 2115 Alt-Rev at 56oC.Keywords: Oil palm, Brassinosteroid, Primer, DNA, GenesABSTRAKÂ Varietas-varietas kelapa sawit yang memiliki daya hasil tinggi umumnya masih memiliki laju pertambahan tinggi yang relatif cepat dan berakibat pada kesulitan saat panen. Brassinosteroid (BRI) merupakan salah satu hormon pertumbuhan yang mengatur pertambahan tinggi batang. Pada studi ini, Sampel yang digunakan adalah tiga jenis kelapa sawit yaitu sampel E. guineensis yang mewakili pertumbuhan tinggi batang kelapa sawit normal, E. oleiferaÂ yang mewakili pertumbuhan tinggi batang lambat, dan hasil persilangan atau hibrida Eo x Eg yang diharapkan mewarisi sifat antara kedua induk yang disilangkan. Sekuensing dilakukan pada sampel menggunakan primer spesifik gen BRI yang memicu pemanjangan dan pembelahan sel batang. Primer Single Nucleotide Amplified Polymorphisms (SNAP) yang digunakan dalam proses analisis perlu dicari suhu optimumnya agar didapatkan kondisi PCR yang optimum sehingga dihasilkan produk PCR yang spesifik. Empat primer Single Nucleotide Amplified Polymorphism (SNAP) yang mendapatkan suhu optimum dengan campuran pereaksi normal yaitu BRI 69 Alt-Rev dan BRI 562 Ref-Rev pada suhu 55oC, BRI 1206 Alt-Rev pada suhu 57oC dan BRI 1206 Ref-Rev pada suhu 58oC. Dua primer membutuhkan tambahan MgCl2 pada campuran pereaksinya yaitu BRI 69 Ref-Rev pada suhu 55oC dan BRI 2115 Alt-Rev pada suhu 56oC.Kata Kunci: Kelapa sawit, Brassinosteroid, Primer, DNA, Gen
Mass Spectrometry Profiling of the Protein Composition of Blood Plasma of Colorectal Cancer Patients

Field: Medicine (Health Sciences)

The objective of the study is themass spectrometry analysis of the protein composition in blood plasma samples of large intestine cancer patients. Protein profiles of 58 blood plasma samples of large intestine cancer patients and healthy volunteers are analyzed using ultrahigh-resolution panoramic mass spectrometry. It is shown that the coincidence of identifications in the protein composition samples of intestine cancer patients and healthy men is 60–80%. Samples of intestines cancer patients contain proteins involved in the interaction with ribonucleic acid, proteins, and lowmolecular substrata.
The Pottery of Megiddo Strata III-II and a Proposed Subdivision of the Iron IIC Period in Northern Israel

Field: Arts and Humanities (Social Sciences)

The Megiddo pottery assemblages of the Iron Age I, IIA, and IIB periods are well known, but those of the Iron IIC have received little attention. In this paper, the Iron IIC pottery assemblages of Strata III and II are presented and discussed. Based on this analysis, it follows that this period can be divided into two phases: the Early Iron IIC and Late Iron IIC. In light of this proposed subdivision, Megiddo and other key sites in northern Israel are analyzed and chronological and historical implications evaluated.
DARATUMUMAB AND EPOCH FOR HIV+/‐ PLASMABLASTIC LYMPHOMA: A FEASIBILITY STUDY OF THE AIDS MALIGNANCY CONSORTIUM (AMC 105)

Field: Medicine (Health Sciences)

Background: Plasmablastic lymphoma (PBL) is a high-grade neoplasm with features of both lymphoma and myeloma. It was originally described primarily in people with HIV in the pre-antiretroviral era and nearly always fatal. However, a recent study of the AIDS Malignancy Consortium with EPOCH showed a 70% two-year event free survival (Ramos, Blood 2020). Currently, the majority of PBL patients do not have HIV (Ciaccio, ASH 2020). We sought to improve outcomes by adding daratumamb (dara), a monoclonal antibody targeting CD38 and used therapeutically in myeloma, to the EPOCH backbone. The primary endpoint of this ongoing study is feasibility of completing ≥3 cycles of protocol therapy. Methods: Patients (pts) with or without HIV and stage II-IV disease are eligible after no more than one prior cycle of CHOP- or EPOCH-like therapy. The target sample size is 15. Dara is administered in cycle 1-3 weekly and held for platelets <25K or ANC <500. In cycles 4–6 dara is given on day 1 only. Missed dara doses are not made up. A total of 12 doses of dara is possible. Pts entering after one cycle of RCHOP/REPOCH-like treatment received 5 cycles on protocol with 11 possible doses. The study was to be stopped if 4 of the first 5-6 patients could not tolerate at least 3 cycles of dara-EPOCH. EPOCH was dose adjusted as reported previously. (Sparano, Blood 2010) If dara was held for 2 complete cycles at any time, pts continued on EPOCH alone. Results: Seven pts have been enrolled, and 5 are evaluable for the primary study endpoint and toxicity. Patient characteristics include HIV (2), Stage II (1), stage IV (4), Ki-67 >80% (4). Two patients had 1 prior cycle off protocol. All five pts received ≥3 cycles of dara-EPOCH. Two pts with 1 pre-protocol cycle completed 5 cycles on study; 2 pts completed 6 total cycles on study. One pt completed 5 cycles on study and is still in treatment. All but 2 doses of planned dara were given for a dose density of 96%. Thus far, 2 pts had grade 4 heme toxicity (2 thrombocytopenia, 1 neutropenia); 3 had grade 3 infection; 1 with grade 3 mucositis. To date, after a median follow up of 10.8 months, 1 patient died of progressive lymphoma after cycle 6. No other disease progression has been noted. Conclusion: We have added daratumumab to EPOCH for PBL, and the early stopping rule has not been invoked following treatment of the first 5 patients. Dose density for planned dara was 96%. Toxicity preliminarily is comparable to EPOCH. The study is enrolling additional patients. The research was funded by: This work was supported by US National Institutes of Health (NIH), National Cancer Institute (NCI) grant UM1 PO1568. It was also supported by US NIH, NCI award P30 CA008748 to Memorial Sloan Kettering Cancer Center. All authors are supported by the US NCI sponsored AIDS Malignancy Consortium Keywords: aggressive B-cell non-Hodgkin lymphoma, chemotherapy, immunotherapy No conflicts of interests pertinent to the abstract.
Antioxidant Activity of Kawista Leaves and Fruit Skin Extract (Limonia acidissima L) from Karawang Regency

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Antioxidants are compounds that can capture free radical activity because they can donate one electron to free radicals. The purpose of this study was to determine how much the antioxidant activity of leaf extract and kawista fruit skin from Karawang Regency. This research is an experimental, the research method used extraction (maceration) with cold aquades, hot aquades, and ethanol 96%. Tested of antioxidant activity can be done by measuring DPPH radical breakfast (1,1-diphenyl-2-picrylhydrazyl) using a UV-Vis spectrophotometer. The results were obtained by the highest antioxidant activity of kawista leaf extract with hot water solvents : 134.56 ppm and the highest antioxidant activity in kawista fruit skin samples achieved by ethanol solvents with a value of 381.36 ppm.
Copper Catalyzed Direct Synthesis of Nitriles from Acyl Azides

Field: Chemistry (Physical Sciences)

Abstract A novel and general protocol for the copper catalyzed reductive elimination of acyl azides to nitriles using triethoxysilane is reported. Various nitriles are obtained in moderate to excellent yields with good functional group tolerance and high chemoselectivity under mild conditions. This new reaction can be performed using a cheap copper catalyst, a simple NHC ligand, an inexpensive silane, and with low catalyst loading.
Subculture of Poverty

Field: Social Sciences (Social Sciences)

The theory of a subculture of poverty, first offered by anthropologist Oscar Lewis to understand the persistence of poverty in rural and urban settings, pervasively persists. The theory asserts that the poor adapt to conditions of poverty and marginality by creating a subculture adapted to those conditions that ensures some degree of normalcy and happiness. This culture sustains poverty by normalizing its supporting value orientations: helplessness, the search for immediate gratification, dependency, marginality, and powerlessness. Criticisms have been widespread and harsh, focusing on the notions that the poor are anything but passive and unthinking beings in the face of social and economic oppression, and that it is problematic to read from human behavior a notion of unfettered human choices. In both cases, the notion of a subculture of poverty is deemed to be simplistic and caricaturing.
Abstract: Multi-site Lymphaticovenular Bypass Using Supermicrosurgery Technique for Lymphedema Management in Lower Lymphedema Cases

Field: Medicine (Health Sciences)

BACKGROUND: The impact of lympahtico-venular anastomosis (LVA) on lymphedema has yet to be defined. The purpose of this study is to investigate clinical evidence on the effectiveness of LVA in lower limb lymphedema1). METHODS: Eighty-four patients (162 limbs, 73 female and 11 male) with lower limb lymphedema who have undergone multi-site LVA procedure in our clinic between August 2010 to May 2014 were included in this retrospective study. Lymphedema was diagnosed using lymphoscintigraphy and ICG lymphograhy. All LVAs were performed under local anesthesia.1 The state of the lymphatic vessels identified during LVA were classified using the NECST Classification.2 Limb circumference, subjective symptoms (Pain, abnormal feeling), and frequency of cellulitis were evaluated. RESULTS: The average age of the patients was 60-years-old (24–94 years old) and the mean post-operative follow-up period was 18.3 months (6–51 months). The postoperative change rate in limb circumference indicated that 67 limbs (47.7%) were classified as “Improvement”, 35 limbs (27.3%) were classified as “Stable”, and 32 limbs (25%) were classified as “Worse”. Post-operative interview revealed improvement in subjective symptoms in 67 limbs (61.5%), no change in 38 limbs (34.9%), and exacerbation in 4 limbs (3.7%). The post-operative mean occurrence of cellulitis was decreased to 0.13 times/year compared with preoperative 0.89, which was statisitically significant (p=0.00084). Multiple regression analysis was performed using the post- LVA limb circumference and NECST classification and the following result was confirmed2). Change Rate (%) = -0.40+(0.30×N)+(-0.84×E)+(0.22×C)+(-0.61×S). CONCLUSIONS: LVA is effective for lower limb lymphedema, in point of limb circumference, subjective symptoms (Pain, abnormal feeling), and the frequency of cellulitis.3 DISCLOSURES:None. REFERENCES: 1. Mihara M, Hara H, Kikuchi K, et al. Scarless lymphatic venous anastomosis for latent and early-stage lymphoedema using indocyanine green lymphography and non-invasive instruments for visualising subcutaneous vein. J Plast Reconstr Aesthet Surg. 2012 Nov;65(11):1551–8. 2. Mihara M, Hara H, Hayashi Y, et al. Pathological steps of cancer-related lymphedema:histological changes in the collecting lymphatic vessels after lymphadenectomy. PLoS One. 2012;7(7):e41126. 3. Mihara M, Hara H, Tange Shuichi et al. Multi-site Lymphaticovenular Bypass using supermicrosurgery technique for Lymphedema Management in lower lymphedema cases. Plastic Reconstructive Surgery (in press)
Efficient Synthesis of Enantiomerically Pure β2-Amino Acids via Chiral Isoxazolidinones

Field: Chemistry (Physical Sciences)

We report a practical and scalable synthetic route for the preparation of alpha-substituted beta-amino acids (beta(2)-amino acids). Michael addition of a chiral hydroxylamine, derived from alpha-methylbenzylamine, to an alpha-alkylacrylate followed by cyclization gives a diastereomeric mixture of alpha-substituted isoxazolidinones. These diastereomers are separable by column chromatography. Subsequent hydrogenation of the purified isoxazolidinones followed by Fmoc protection affords enantiomerically pure Fmoc-beta(2)-amino acids, which are useful for beta-peptide synthesis. This route provides access to both enantiomers of a protected beta(2)-amino acid.
Emotion Recognition under Sleep Deprivation Using a Multimodal Residual LSTM Network

Field: Computer Science (Physical Sciences)

Emotion recognition under sleep deprivation is instructive for the study of mental disorders such as major depressive disorder. Previous studies on emotion recognition under sleep deprivation have been mainly based on psychological research techniques. In this paper, we introduce a multilayer weight-sharing multimodal residual LSTM network for emotion recognition under sleep deprivation. The advantage of our proposed method is that it allows for the combination of three different features: the electroencephalography (EEG) single-channel differential entropy (DE) features, EEG functional strength features with topological correlation connectivity, and eye movement features. The experiments under the conditions of sleep deprivation, sleep recovery and baseline are designed and conducted. The experimental results demonstrate that the proposed method significantly enhances the performance compared with the simple concatenation of the features of different modalities, and the best mean accuracies of 86.86% and 82.03% are achieved for four emotions (happiness, sadness, fear, and neutral) in subject-dependent and cross-subject emotion recognition tasks under 30 hours of sleep deprivation, respectively. The classification accuracy of the happiness emotion is obviously impaired under sleep deprivation, indicating that sleep deprivation impairs the stimulation of the happiness emotion, and one night of sleep recovery can reactivate the elicitation of the happiness emotion to the baseline level. Furthermore, we study the brain neural patterns of the four emotional states. The prefrontal area becomes less activated for the happiness emotion and sadness emotion in the gamma band under sleep deprivation, while the neural pattern of the fear emotion is highly robust with respect to sleep deprivation.
An Alternative Algorithm For Forward Resource Scheduling in CDMA2000-1X EVDO Network

Field: Computer Science (Physical Sciences)

G-fair algorithm is popularly used for forward resource scheduling in CDMA2000-1X EVDO network.It is generally acknowledged that G-fair algorithm takes into account both maximum system throughput and fairness.However, according to the result of simulation and test in actual network, when G-fair algorithm is used, the resource allocated to users in poor wireless environment is far less than that to users in excellent wireless environment, and the data rate of users in poor wireless environment is very low.In order to improve this situation, we discuss in the paper the possibility of using equal opportunity algorithm for forward resource scheduling in CDMA2000-1X EVDO network, and also introduce the experiment result and effect in actual network .
Officer Sabbaticals: Analysis of Extended Leave Options

Field: Social Sciences (Social Sciences)

In recent years the Department of Defense (DoD) has placed increasing focus on attracting and maintaining military personnel with desirable skills and capabilities and on creating a more flexible personnel system to prepare the military for the future. To achieve these goals and as part of its developing human resource strategy, DoD is exploring a wide range of personnel management programs. One such program involves the greater rise of extended leaves for its military officers.
Teaching with TikTok in Online Sociology of Sex and Gender Courses

Field: Social Sciences (Social Sciences)

Maintaining class participation and engagement poses a unique challenge in teaching online courses at postsecondary institutions. With the distinctive rise of online instruction during the COVID-19 pandemic, there is a critical need to develop innovative and exciting opportunities in online course concept learning, application, and peer-to-peer engagement. To fulfill this need, I utilized the popular social media app TikTok to help students engage with sociological insights and concepts during course participation activities in two asynchronous, online Sociology of Sex and Gender courses at the University of South Carolina. TikTok is an online-sharing platform that allows users to create short videos with music and visual effects. TikTok can also be a valuable tool for increasing student engagement in online sociology courses. In this article, I describe this teaching activity, present findings of the preliminary teaching evaluation, and discuss the potential impact of using TikTok in online sociology courses.
Biomechanical Characterization of Human Corneal Lenticules

Field: Medicine (Health Sciences)

Abstract In surgical refractive interventions over-correction or under-correction still occur in 10-15 % of cases. Improved outcomes could be achieved by incorporating patient-specific corneal biomechanics into surgical planning. As a first step, this study mechanically characterizes and numerically simulates corneal lenticules harvested during a refractive intervention called Corneal Lenticule Extraction for Advanced Refractive Correction (CLEAR). These human corneal lenticules were mechanically tested in uniaxial extension in nasal-temporal and 45 deg orientations. An HGO material model that accounts for the unique collagen arrangement of the human cornea was developed and used to identify the material parameters using a finite element model of the experimental setup. The material parameters that best represent the experimental force/displacement were obtained by parameter estimation using Bayesian optimization. The uniaxial experiments performed on 3 patients did not show distinctive differences in orientation. The estimated material parameters fit well with the experimental data, representing a promising material model. In the future, Brillouin measurements will be performed on the CLEAR patients before lenticule extraction so that material parameters can be estimated in vivo, providing the surgeon with a patient specific-surgical planning tool.
Assessing the effect of interpersonal communications on employees' commitment and satisfaction

Field: Business, Management and Accounting (Social Sciences)

Purpose The purpose of this paper is to examine the relationship between employees' motives for communicating with superiors and coworkers, their commitment to their organizations, satisfaction with jobs, and with superiors. Design/methodology/approach This article makes use of survey research, using quantitative research methodology investigating employees' motives for communicating with their superiors and co‐workers, their satisfaction and commitment towards their organization. The research identifies pleasure, escape, relaxation, control and inclusion as motives explaining why people communicate with each other and how they relate to each other. Findings The findings revealed a relationship between the motives along with satisfaction and commitment. Employees report a moderate commitment with their coworkers as well as superiors. Furthermore, the results showed strong relationships between the control, affection, inclusion, escape and relaxation motives. Research limitations/implications The research showed strengthening communication ties from a need to encourage more healthy interpersonal relationships by using jointly constructed reality. This approach was more effective because it goes beyond information process and it involves the process of people together creating what will be the mission and vision of the organization and developing corporate values. In addition, the organization's commitment can be enhanced through job enrichment together with matching the individual's values to those of the organization besides, finding ways and means of improving job satisfaction through different strategies such as improving the quality of the supervision, decentralization of power and counselling. Finally, the investigation serves as a context for evaluating the applicability of previous studies to the manufacturing, oil and petrochemical industries in Bahrain, focusing on Bapco (Bahrain Petroleum Company), GPIC (Gulf Petrochemicals Industries) and ALBA (Aluminum Bahrain ). Originality/value The study is the first thorough study conducted in the three above‐mentioned organizations. Therefore, it would be of great value to understand their employees better and improving their communication ties as well as motivation.