jimnoneill/paper-to-field-training huggingface dataset:
Circulating regulatory T cells in "clinical" monoclonal B-cell lymphocytosis

Field: Medicine (Health Sciences)

Abstract \n \n \nRegulatory T-cells (Tregs) constitute a small subset of cells involved in antitumour immunity and are generally increased in patients with chronic lymphocytic leukemia (CLL). No data is available on Tregs in monoclonal B-cell lymphocytosis (MBL), a disease entity characterized by less than 5000/microL circulating clonal B-cells in absence of other features of lymphoproliferative disorders. We used multicolour flow cytometry to evaluate the number of circulating Tregs in 56 patients with &#x0022;clinical&#x0022; MBL, 74 patients with previously untreated CLL and 40 healthy subjects. MBL patients showed a lower absolute number of Tregs, compared to CLL patients, but slightly higher than controls. Moreover, the absolute cell number of Tregs directly correlated both with more advanced Rai/Binet clinical stages and peripheral blood B-cell lymphocytosis. Of note, the absolute number of Tregs was found lower in MBL patients than in CLL patients staged as 0/A Rai/Binet. The study showed that Treg increase gradually from normal subjects to &#x0022;clinical&#x0022; MBL patients and are significantly higher in CLL patients as compared to MBL patients. Moreover, a significant direct relationship was found between higher Treg values and a higher tumor burden expressed by B-lymphocytosis or more advanced clinical stages. In light of this data, MBL seems to be a preliminary phase preceding CLL. The progressive increase of Treg numbers might contribute both to the clinical evolution of MBL to overt CLL and to CLL progression.
Tuberculosis - HIV Coinfection Patients Among TB Patients In Dr. Moewardi Hospital Surakarta Year 2008-2009

Field: Medicine (Health Sciences)

Introduction: Tuberculosis is the commonest opportunistic infection and the
number one cause of death in HIV patients. Human immunodeficie0ncy virusinfected
people are more susceptible to be infected when they are exposed to
Mycobacterium tuberculosis. The immunosuppression induced by HIV modifies
the clinical presentation of TB, resulting in atypical signs and symptoms, increase
in smear negative acid fast bacili and atypical findings on chest radiography.The
objective of this study is to describe TB-HIV coinfection patients among TB
patients according to clinical signs and symptoms, smear of acid fast bacili, chest
radiography and treatment outcome .
Methods : Descriptive retrospective design study on 49 TB-HIV coinfection
patients in Dr.Moewardi Hospital Surakarta from January 1st 2008 to December
31st 2009. Datas were collected from medical records, VCT clinic and DOTS
reports.
Results : There are 49 patients TB-HIV coinfection, it’s about 7,17% among
patients TB non HIV and about 37,77% among ODHA non TB, with most average
age is 21-39 year (83,70%) and mostly are men (77,55%). Smears positive acid
fast bacili were found on 10 patients (20,40%%), 32 patients (65,30%) are
negative. The Most clinical signs and symptoms are productive cough (28,5%)
and dyspnoe (28,5%). Radiological features of TB-HIV coinfection show diffuse
fibroinfiltrate on 13 patients (26,54%) and only one (2,04%) with cavitary pattern.
Cluster differentiation (CD 4+) count from 29 patients are < 200 cells/mm3.
Treatment outcome for TB-HIV coinfection patients 18,37% are cured, 53,06%
completed treatment, died for treatment complexion are 26,53%.
Conclusions : Commonest chief complain among TB-HIV coinfection are
productive cough and dyspnoe, smears positive were found on 20,40% patients,
radiological features show diffuse fibroinfiltrate (26,54%), complete treatment
(53,06%) is the most outcome treatment.
Key words : TB-HIV coinfection, TB non HIV
Factors in the Length of Stay of Homeless Families in Temporary Accommodation

Field: Social Sciences (Social Sciences)

Data relating to 526 homeless families in temporary accommodation were collected in a study directed mainly to the examination of support networks of a sample of these families. The data, however, have allowed the authors to examine the effects of certain characteristics of these families on the average length of stay in temporary accommodation before they were housed permanently. Log-linear analysis was used to establish the independent effect of various attributes available from the data. In general the feature which seemed to influence the length of stay most was the time of the year when the family was admitted into temporary accommodation followed by the sort of reason the families gave for being homeless at the time of admission. Those who had been illegally evicted tended to take longer to be rehoused whilst those with rental or tenant difficulties took less time to be rehoused. The authors are then able to produce profiles based on this analysis of those families which are likely to stay longest in temporary accommodation as against those likely to stay the shortest time.
Youth Heterotopias in Precarious Times

Field: Social Sciences (Social Sciences)

Under the structural restraints of the current financial, social and political crisis, I examine the case of a collectivity of students in Greece as an alternative small-scale form of political and cultural action, and I explore its dynamics and limits. I claim that the ‘collectivity’ is a form of heterotopia, that is, a specific social and cultural space, which somehow reflects and at the same time distorts, unsettles or inverts other spaces. In particular, I seek to uncover the rituals, practices and mentalities produced by the participants of this youth cultural space, and to understand how new subjectivities and collectivities come into being. In this context, I discuss some of the relevant literature on youth political participation. Furthermore, I illustrate the debate about ‘autonomy’ and ‘hegemony’ within social and political theory today.
"Safe from Utopia?" : the LSD controversy in Saskatchewan, 1950-1967

Field: Social Sciences (Social Sciences)

The controversy surrounding the use of LSD as an adjunct to psychotherapy for alcoholics in Saskatchewan has not been explored by social or medical historians. From 1950 to 1967, Saskatchewan psychiatrists developed new treatments for chronic alcoholism by using LSD on themselves, on volunteers and finally on patients. Despite early success and praise, the use of LSD in psychotherapy was later condemned by the media, the general public, the medical profession and eventually the federal government and was discontinued after being banned in 1967. The reasons for the ban were far-reaching and diverse. LSD was exploited by the counter-culture for "kicks" and was later abandoned by pharmaceutical companies because of the negative reputation lay-professionals and the media had bestowed upon its therapeutic use. As it turned out, legitimate LSD research became too clouded in controversy to survive the 1960s as researchers failed to convince the masses that the drug did not pose a threat to the well-being of society. In many respects, the LSD controversy can be seen as more of a moral panic than a scientific debate. Nevertheless, the LSD controversy provides a unique and much needed look into the history of medicine from a social perspective, illustrating that social values often have more impact on medical research than empirical validity. As recent evidence suggests, the psychotherapeutic potential of LSD -- as developed by Saskatchewan psychiatrists -- has not been forgotten. Indeed, a renewal of interest in LSD research has surfaced in several U.S. states as American psychiatrists are discovering, once again, that LSD can be a valuable psychiatric research tool.
Social recognition as an equal: The role of equality‐based respect in group life

Field: Psychology (Social Sciences)

Abstract The study presented in this article examined the role of social recognition as an equal in group members' motivation to serve their ingroup as well as actual group‐serving behavior. We predicted and found that social recognition as opposed to non‐recognition as an equal, communicated by fellow group members, increased participants' group‐serving motivation and behavior. In addition, the psychological processes underlying this effect were examined. We theoretically derived a mediational chain, which was then tested empirically. As expected, social recognition as an equal led to experiences of being respected, and perceived equality of self played a mediational role in this relationship. The experience of respect, in turn, was associated with stronger collective identification, which played a mediating role linking the respect experience with higher motivation and better behavioral performance in group‐serving tasks. Moreover, these effects operated over and above group members' perceptions of being liked by others. The practical and broader social implications of equality‐based respect are discussed. Copyright © 2011 John Wiley & Sons, Ltd.
Translating national standards into practice for the initial training of Further Education (FE) teachers in England

Field: Social Sciences (Social Sciences)

Over the last decade the system for training FE teachers in England has been the subject of almost continuous government reform. Central to the reforms has been the definition of national standards as the foundation for qualifications and training. This paper focuses upon how standards for FE teachers are translated as they move from the worlds of policymakers to those of practitioners. The term ‘translation’ suggests that many actors are involved in interpreting and using standards as they cross organisational boundaries. Socio‐cultural perspectives, from the Vygotskian tradition, are employed to analyse the roles standards have in mediating practice. Although the paper concentrates upon the impact of the introduction of standards on the initial training of FE teachers, the central thrust of analysing how standards are translated from policy into pedagogy has wider relevance because of the current predilection of governments for standards‐led reform.
The Theodosian Code - (S.) Crogiez-Pétrequin, (P.) Jaillette (edd.) Codex Theodosianus. Le Code Théodosien V. Pp. 523, figs. Turnhout, Belgium: Brepols, 2009. Cased, €125. ISBN: 978-2-503-51722-3.

Field: Arts and Humanities (Social Sciences)

The Theodosian Code - (S.) Crogiez-Pétrequin, (P.) Jaillette (edd.) Codex Theodosianus. Le Code Théodosien V. Pp. 523, figs. Turnhout, Belgium: Brepols, 2009. Cased, €125. ISBN: 978-2-503-51722-3. - Volume 61 Issue 1
Wideband characterization of dielectric material by new approaches based on near field microwave microscopy

Field: Engineering (Physical Sciences)

We present in this paper an electromagnetic model based on finite elements method for the characterization of dielectric samples with a near field microwave microscopy, this proposed model is a useful tool to determine for, a given microcopy probe, the minimum substrate thickness required to extract accurately the substrate relative permittivity and loss tangent. This paper proposes a practical application with a wideband characterization apparatus.
Isolation and characterization of diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase from Physarum polycephalum

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

A new enzyme that hydrolyzes diadenosine 5',5"'-P1,P4-tetraphosphate has been purified by a factor of 250 from the acellular slime mold Physarum polycephalum. Activity was assayed radioisotopically with [3H]Ap4A. Isolation of the enzyme was facilitated by dye-ligand chromatography. The enzyme symmetrically hydrolyzes Ap4A to ADP and exhibits biphasic kinetics for the substrate with values for the apparent Km of 2.6 micro M and 37 micro M. The two values of Vmax differ by a factor of 10. Mg2+, Ca2+, and other divalent cations inhibit the activity with 40-80% inhibition occurring at 0.5 mM. Mg2+, at 0.5 mM, decreases both values of Vmax by 50%, decreases the low Km value by about 30%, and increases the high Km value by about 100%. (Ethylenedinitrilo)tetraacetic acid (EDTA) and [ethylenebis(oxyethylenenitrilo)]tetraacetic acid (EGTA), at 10 mM, inhibit the activity by 50%. ADP, ATP, Ap4, and Gp4 are equipotent inhibitors with 50% inhibition occurring at 30 micro M. AMP is a relatively weak inhibitor. The molecular weight of the enzyme is 26000 on the basis of elution of activity from a calibrated Sephadex G-75 column.
WRIT8497-PWF.Independent Study.F16.Francisco,Patricia

Field: Arts and Humanities (Social Sciences)

An independent study course is an opportunity to do independent work under the direction of a faculty member. The student and instructor work out a course of study before the term begins and typically meet four to six times during the term to discuss readings and papers. Unless there are special circumstances, students may take only one independent study. Special registration required. Please contact your advisor or the program office.
EasyAnimate: A High-Performance Long Video Generation Method based on Transformer Architecture

Field: Computer Science (Physical Sciences)

This paper presents EasyAnimate, an advanced method for video generation that leverages the power of transformer architecture for high-performance outcomes. We have expanded the DiT framework originally designed for 2D image synthesis to accommodate the complexities of 3D video generation by incorporating a motion module block. It is used to capture temporal dynamics, thereby ensuring the production of consistent frames and seamless motion transitions. The motion module can be adapted to various DiT baseline methods to generate video with different styles. It can also generate videos with different frame rates and resolutions during both training and inference phases, suitable for both images and videos. Moreover, we introduce slice VAE, a novel approach to condense the temporal axis, facilitating the generation of long duration videos. Currently, EasyAnimate exhibits the proficiency to generate videos with 144 frames. We provide a holistic ecosystem for video production based on DiT, encompassing aspects such as data pre-processing, VAE training, DiT models training (both the baseline model and LoRA model), and end-to-end video inference. Code is available at: https://github.com/aigc-apps/EasyAnimate. We are continuously working to enhance the performance of our method.
Technological Proposal for Reduction of Residual Lubricating Oil In Oil Filters Removed from Automotive Engines

Field: Engineering (Physical Sciences)

<div class="section abstract"><div class="htmlview paragraph">In this study, a prototype oil filter was developed as a replacement for the shielded filters currently used in automotive applications. The goal was to reduce the residual lubricating oil disposed with a used filter. This is considered a Class I, waste (dangerous), under NBR 10004. Current Brazilian legislation, including CONAMA Resolution No. 362 of 2005, prioritizes the collection and disposal of used lubricating oil, and requires all contaminated material to be recycled or, where current technology does not permit this, to be sent to industrial landfills certified to handle toxic waste. To quantify the volume of residual oil in a commercial shielded oil filter, an experiment was conducted using 120 samples of a standard model. These samples were weighed before and after use. Before developing our novel design, a survey was conducted of professionals from the automotive field, to identify the main opportunities for progress. On the basis of the useful suggestions provided, a digital model and later a prototype were developed. The prototype was tested in an Otto cycle engine for 20,000 km. The oil retained in a conventional shielded filter and in the prototype was compared. The volume of lubricating oil retained by the commercial shielded filter, after use and drainage, was 118.4 ml on average, compared with 39.0 ml for the prototype, a reduction of 67%. Extrapolating this reduction to the 2015 Brazilian fleet of 48,226,804 cars the results suggest that approximately 4 million liters of extra lubricating oil could be sent directly for re-refining, without requiring further separation after the filter exchange.</div></div>
A Study of Sense of Self-agency Focused on Cross-correlation and Delay Between Action and Effect in Continuous Operation

Field: Psychology (Social Sciences)

Sense of self-agency has been proposed in psychology field, and it is the sense that I am the initiator or source of the action. We discuss it on continuous operation to find out the transition of the sense for a change of delay and cross-correlation that is the degree of noise between an action as an input signal and its effect as an output signal. We conclude that sense of self-agency is affected by both of a cross-correlation and a delay, human gets stronger sense of self-agency when cross-correlation between action and effect is higher, and an acceptable noise and delay to feel enough good operational feeling may be predicted.
LyondellBasell is getting green bonds

Field: Business, Management and Accounting (Social Sciences)

LyondellBasell Industries is launching a public offering of green bonds. The principal of the bonds will be $500 million and will bear a 5.625% interest rate. The proceeds from the bonds will go toward circular economy, renewable energy, pollution prevention, and energy efficiency projects. Green bonds have become popular as a way to connect chemical companies with investors interested in backing sustainability. In March, Air Products raised more than $1.3 billion in two bond offerings that it intends to use for low-carbon ammonia and sustainable aviation fuels, and Eastman Chemical closed a $500 million green bond offering.
Medicago italica (Mill.) Fiori APG 31358

Field: Agricultural and Biological Sciences (Life Sciences)

Plant Genetic Resource.
Taxonomy: Medicago italica (Mill.) Fiori
Common name(s): Medics
Other names: SA 31358
Conserved by: Australian Pastures Genebank of the South Australian Research and Development Institute (APG), Australia
Local sample unique identifier: APG 31358
Method of creation: Acquisition
Date: 1993-08-01
Other identifiers: n/a,C3101880101B, n/a,SA 31358, n/a,ALP 1.55
Historical: No
Biological status: Wild
MLS status: Included
Grade repetition, school drop-out and ineffective school policy

Field: Social Sciences (Social Sciences)

This paper investigates the extent of underperformance, grade repetition and drop-out rates in selected underperforming schools in Amathole West District, Eastern Cape. The findings revealed high failure rates in the selected schools throughout the five years included in the investigation. The findings revealed a high failure rate persisted in the selected schools throughout the five years included in the investigation. Key informants in the study, including teachers and principals, attribute some of the high failure rate to the Promotion and Progression Policy. The chief criticism is that the burden of catching these learners up falls on the teachers while learners exert minimum effort. In addition to the promotion policy and poor resourcing, other in-school and out-of-school factors influence academic performance at the selected schools, such as weak and inconsistent leadership manifested in fluctuating pass rates over the years.
Profiling the performance of P4080DS

Field: Computer Science (Physical Sciences)

This report presents the method to test and profile the performance of P4080, an eight-core processor by Freescale, using two approaches, the hypervisor approach and the hardware approach. The focus is to explore the cache partitioning and memory partitioning functions of P4080DS and how this could affect the performance in terms of execution time and cache hit ratio. This report contains detailed procedures of both hypervisor approach and hardware approach. The hypervisor approach created 8 partitions by modifying the device tree of hypervisor. Similarly, the hardware approach created 8 partitions by configuring the internal register sets. With partitioned system, 4 sets of experiments were conducted to test and compare the performance of P4080DS in different situations. The results suggested that the performance of individual partition is independent of number of cores running simultaneously. The results also showed that the measured hit ratios of individual partition match with the theoretical values.
An M.S. External Degree Program at the Naval Weapons Center: An Innovation

Field: Engineering (Physical Sciences)

This paper describes an External Degree program for a Master's degree in engineering with emphasis on electrical engineering options. The program is offered at the Naval Weapons Center at China Lake, CA (located 150 mi north of Los Angeles) where there is a large body of technical personnel engaged in sophisticated research and development in advanced defense systems. The faculty is selected from among NWC personnel, and the program is closely monitored by the senior engineering faculty of California State University, Northridge.
LED photobiomodulation therapy associated with heterologous fibrin biopolymer optimizes wound repair in rats

Field: Medicine (Health Sciences)

This study aimed to evaluate the effect of LED photobiomodulation therapy associated or not with heterologous fibrin biopolymer to repair skin wounds in rats. Full-thickness skin wounds were induced on the back of 84 Wistar rats and they were randomly divided into 4 groups: control group (CG), LED group (LED), heterologous fibrin biopolymer group (HFB), and LED + heterologous fibrin biopolymer group (LED + HFB). The animals were euthanized at 7, 14, and 21 days after surgery. In the macroscopic findings, it was observed in the control group, mild local inflammation, evidenced between the 5th and 6th day after the injury, not manifested in the other groups. The analysis of the wound reduction index shown that the treated groups presented greater wound reduction in the three periods evaluated. The results of the degree of inflammation showed that the LED and LED + HFB groups showed a predominance of chronic inflammation, while the control group showed a predominance of diffuse acute inflammation. The quantity of type I collagen it was bigger after 7 days in the LED and LED + HFB groups, and at 14 and 21 days this type of collagen appears more intensely in the group that used only HFB. The traction force at 7 days of the experiment, the treated groups showed better performance, while at 14 and 21 days the group that used only the biopolymer obtained greater strength in the suture region. Results have indicated that treatments using HFB and LED, either isolated or associated, stimulated the wound repair process in rats. HFB promote collagen maturation.
Applied physiology: neuropathic pain

Field: Neuroscience (Life Sciences)

This chapter focuses on peripheral and spinal mechanisms of neuropathic pain. Inflammatory mediators can produce excitation of neurons in the peripheral nervous system and central nervous system. Nerve injury can lead to cell death and anatomical reorganization. A loss of inhibitory mechanisms and increase in excitatory mechanisms are associated with increased activity in the spinal cord in neuropathic pain. Microglia is activated in neuropathic pain and release pronociceptive substances which can activate neurons in the spinal cord. Unravelling the mechanisms involved in neuropathic pain requires the use of laboratory animal models that replicate as far as possible the different pathophysiological changes present in patients. The sensory input from primary sensory neurons is transferred, via their central axons, to second-order neurons in the dorsal horn of the spinal cord. In addition to the peripheral and spinal mechanisms discussed, supraspinal mechanisms are thought to play an important role in neuropathic pain.