jimnoneill/paper-to-field-training huggingface dataset:
The costs of nonsedating antihistamine therapy for allergic rhinitis in managed care: an updated analysis.

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Consistent with our prior study, loratadine and cetirizine were generally associated with significantly higher treatment charges than fexofenadine. This result was observed across different stratifications of patients, including those with comorbid respiratory illness, concomitant use of nasal steroids, and asthma and/or sinusitis. These results provide further useful insights into the differential costs associated with the use of nonsedating antihistamines for allergic rhinitis treatment.
Organization of Inhibitory Frequency Receptive Fields in Cat Primary Auditory Cortex

Field: Neuroscience (Life Sciences)

Based on properties of excitatory frequency (spectral) receptive fields (esRFs), previous studies have indicated that cat primary auditory cortex (A1) is composed of functionally distinct dorsal and ventral subdivisions. Dorsal A1 (A1d) has been suggested to be involved in analyzing complex spectral patterns, whereas ventral A1 (A1v) appears better suited for analyzing narrowband sounds. However, these studies were based on single-tone stimuli and did not consider how neuronal responses to tones are modulated when the tones are part of a more complex acoustic environment. In the visual and peripheral auditory systems, stimulus components outside of the esRF can exert strong modulatory effects on responses. We investigated the organization of inhibitory frequency regions outside of the pure-tone esRF in single neurons in cat A1. We found a high incidence of inhibitory response areas (in 95% of sampled neurons) and a wide variety in the structure of inhibitory bands ranging from a single band to more than four distinct inhibitory regions. Unlike the auditory nerve where most fibers possess two surrounding “lateral” suppression bands, only 38% of A1 cells had this simple structure. The word lateral is defined in this sense to be inhibition or suppression that extends beyond the low- and high-frequency borders of the esRF. Regional differences in the distribution of inhibitory RF structure across A1 were evident. In A1d, only 16% of the cells had simple two-banded lateral RF organization, whereas 50% of A1v cells had this organization. This nonhomogeneous topographic distribution of inhibitory properties is consistent with the hypothesis that A1 is composed of at least two functionally distinct subdivisions that may be part of different auditory cortical processing streams.
[Cyclic AMP accumulation in psoriatic skin: differential responses to epinephrine, AMP and histamine (author's transl)].

Field: Medicine (Health Sciences)

Epidermal adenylate cyclase can be activated independently by epinephrine, adenosine and histamine resulting in the accumulation of cyclic AMP. Using the uninvolved and involved keratome-sliced skin from psoriatic patients, we investigated the effects of these agents in vitro on the intra-cellular cyclic AMP levels of the skin. In the involved skin of psoriasis, epinephrine-induced cyclic AMP accumulation was decreased, whereas no decrease in adenosine- or histamine-induced cyclic AMP accumulation was seen. Since keratome-sliced skin samples had various amounts of dermal contamination, we also investigated the effect of epinephrine on the "pure" epidermal cyclic AMP level. After the incubation with epinephrine, pure epidermal samples, which were micro-dissected free from stratum corneum, dermis and skin appendages, were assayed for cyclic AMP level. Again cyclic AMP accumulation was decreased in the involved skin. Thus epinephrine-induced cyclic AMP accumulation was shown to be decreased in the involved epidermis of psoriasis.
Synthesis of (+)- and (−)-Tetrabenazine from the Resolution of α-Dihydrotetrabenazine

Field: Chemistry (Physical Sciences)

Abstract Tetrabenazine (1) was reduced with NaBH4 to α-dihydrotetrabenazine (2) and then resolved with di-p-toluoyl-L-tartrate and di-p-toluoyl-D-tartrate to subsequently give (+)- and (−)-α-dihydrotetrabenazine. The enantiomers were oxidized under Swern conditions to prepare samples of (+)-tetrabenazine and (−)-tetrabenazine. The samples were optically pure by chiral HPLC analysis.
Reproductive Cycle of the Edible Sea Urchin Paracentrotus lividus (Lamarck, 1816) (Echinodermata: Echinoidea) in the Coastal Region El Jadida-Safi (Atlantic Ocean, Morocco)

Field: Agricultural and Biological Sciences (Life Sciences)

Reproductive Cycle of the Edible Sea Urchin Paracentrotus lividus (Lamarck, 1816) (Echinodermata: Echinoidea) in the Coastal Region El Jadida-Safi (Atlantic Ocean, Morocco) The Sea urchins populations of P. lividus had an annual reproductive cycle that was synchronous across sites and between males and females. The histology of the gonads revealed six different stages: Recovering, Growing, Premature, Mature, Partly spawned and Spent. Maturation occurred between March and late April while spawning period occurred in May and early August with little difference between sites. The Gonad indices showed a peak from late winter to early spring. A perfect correlation observed between the gonad index and the histological results suggests that the gonad index decreases when the individual is spawning. Nevertheless, the GI seems to be influenced by abiotic factors particularly sea water temperature in the first station (Sidi Bouzid) and the food richness of the environment in the second station (Ain Darak).
Introducing Indus Keyboard - A first of its kind interactive tool to visualize the Indus Script in Devanagari and Brahmi

Field: Arts and Humanities (Social Sciences)

We introduce Indus Keyboard, a web-based interactive tool that renders Devanagari text in the Indus script, based on the decipherment proposed by Yajnadevam. This is the first known keyboard to implement such a mapping for the Indus Script, achieved through two custom-designed fonts created using FontForge. The primary font renders Devanagari input as Indus signs based on frequency of occurrence including contextual ligatures (wherever attested), and displays them right-to-left, preserving the original directionality of the script. A secondary Brahmi style font visualizes Brahmi standardized Indus glyphs alongside their corresponding Brahmi text rendered left-to-right, enabling easy comparison and contrast, highlighting the possible evolution of the Indus script to Brahmi over millennia. The keyboard is built entirely using standard web technologies (HTML, CSS, and JavaScript) and runs fully in-browser. Indus Keyboard offers a novel tool for researchers, educators, and script enthusiasts interested in early writing systems and their visual interrelationships.
Novel Cationic Lipids Based on Malonic Acid Amides Backbone: Transfection Efficacy and Cell Toxicity Properties

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Gene delivery using nonviral approaches has been extensively studied as a basic tool for intracellular gene transfer. Despite intensive research activity, the aim of creating a vector which meets all necessary demands has still not been reached. One possibility to solve the nonviral vector associated problem of low transfection efficacy is the development of new cationic amphiphiles. Therefore, the non-glycerol-based cationic lipids 1-9 have been synthesized and tested for in vitro gene delivery experiments. The backbone structure of the lipids consists of a malonic acid diamide with two long hydrophobic chains. The degree of saturation of the hydrophobic chains and the structure of the polar cationic headgroup were varied. The preparation follows an easy process and facilitates the trouble-free insertion of different alkyl chains. By studying in vitro gene delivery an increase of transfection efficacy was observed when using at least one unsaturated alkyl chain in the hydrophobic part and lysine or bis(2-aminoethyl)aminoethylamid as hydrophilic headgroup. This leads to cationic lipids exhibiting comparable or even higher transfection efficacies compared to the commercially available LipofectAmine and SuperFect.
Asymptotics of prediction in functional linear regression with\n functional outputs

Field: Mathematics (Physical Sciences)

We study prediction in the functional linear model with functional outputs :\n$Y=SX+\\epsilon $ where the covariates $X$ and $Y$ belong to some functional\nspace and $S$ is a linear operator. We provide the asymptotic mean square\nprediction error with exact constants for our estimator which is based on\nfunctional PCA of the input and has a classical form. As a consequence we\nderive the optimal choice of the dimension $k_{n}$ of the projection space. The\nrates we obtain are optimal in minimax sense and generalize those found when\nthe output is real. Our main results hold with no prior assumptions on the rate\nof decay of the eigenvalues of the input. This allows to consider a wide class\nof parameters and inputs $X(\\cdot) $ that may be either very irregular or very\nsmooth. We also prove a central limit theorem for the predictor which improves\nresults by Cardot, Mas and Sarda (2007) in the simpler model with scalar\noutputs. We show that, due to the underlying inverse problem, the bare estimate\ncannot converge in distribution for the norm of the function space\n
Testing for time variation in the natural rate of interest (replication data)

Field: Economics, Econometrics and Finance (Social Sciences)

This paper replicates in a wider sense the unobserved components model of Laubach and Williams (Review of Economics and Statistics, 2003, 85, 1063-1070) to estimate the natural rate of interest (NRI) and investigates the role of model uncertainty. A stochastic Bayesian model selection procedure is employed to test the hypothesis of time variation in the NRI against a constant NRI. The model selection confirms time variation in the NRI as a result of changes in potential output growth, but other determinants of the NRI are found constant.
Ancient “church goods” in Norfolk

Field: Arts and Humanities (Social Sciences)

Journal Article Ancient “church goods” in Norfolk Get access G. F. Barrow, M.A. G. F. Barrow, M.A. 1Westminster Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume s5-XI, Issue 274, 29 March 1879, Pages 242–243, https://doi.org/10.1093/nq/s5-XI.274.242b Published: 29 March 1879
A Study on the qGoing outq Paths of Tourism Industry of TCM Health Preservation Culture Driven by One Belt, One Road

Field: Social Sciences (Social Sciences)

This article first reviewed the history and present situation of TCM health preservation culture in Shaanxi province, and analyzed several problems that Shaanxi tourism industry of TCM preservation health culture faces.Based on these problems, the author put forward "going out" paths of Shaanxi tourism industry of TCM preservation health culture.The purpose of this paper aims to make some explorations for the development of tourism industry of TCM health preservation culture in tourism 4.0 era driven by One Belt, One Road initiative.
Robust methods for AOA geo-location in a real-time indoor WiFi system

Field: Engineering (Physical Sciences)

Indoor localisation technologies have received considerable attention in recent years and they are applicable in many fields. As with outdoor systems, they both suffer a degradation in performance when multi-path errors are present. Applications include locating essential equipment in hospitals and specific items in warehouses, tracking people with special needs, who are away from visual supervision, and navigating fire-fighters inside buildings. In this article, we study issues associated with the implementation of a real-time Wireless Fidelity (WiFi) localisation system for an indoor environment. In particular, we present robust techniques to mitigate the effects of the multi-path errors. This system utilises smart antennas to determine the signal strength information from a mobile target (MT) (access point) and send the information to a data processing station. This information is combined to find the direction of arrival of the signal and triangulate the MT position. No prior finger-printing is required, as this system avoids the use of an off-line training phase, which is computationally intensive and requires a big database. This approach is more computationally efficient and non-data intensive. Experimental results show an improvement in the accuracy of the localisation system over conventional techniques.
Impact of Employee Grievance Management on Organizational Performance

Field: Business, Management and Accounting (Social Sciences)

Purpose: This paper examined the impact of employees' grievance management on organizational performance. The paper derives from conceptual points of view in available literatures that there is a coefficient relationship between the variables: employees' grievances, and organizational performance; hence, effective management of employee grievance is essential for harmonious workplace relationship, team spirit, employees' loyalty and commitment, as well as improved organizational productivity and performance. In the face of this necessity, there is still a relative lack of, or poor employee grievance management in organizations thereby giving rise to negative organizational outcomes such as reduced productivity, absenteeism, violation of orders, indiscipline and reduced quality of work. The study thus aims to show how employees' grievances directly impact on performance. Methodology: In doing this, the study is designed using secondary data, analyzed in line with content analysis model and developed on the theoretical foundation of Rahim and Bonoma’s grievance management model. The analysis is anchored on two research objectives and research questions, developed to test recurrent hypotheses. Findings: From the findings, the study concludes that effective employee grievance management is vital for effective harmonious management-labour relationship which helps to enhance organizational performance. Recommendations: It is recommended among others that grievances should be handled routinely through set-up structures designed exclusively for that purpose in order to drastically reduce employees' grievances in the workplace.
Agricultural extension services in Bangladesh: a review study

Field: Agricultural and Biological Sciences (Life Sciences)

tt~·~~~w~m~~ m~w*-tt~~W~~~*­ Agricultural Extension Service aims to educate the people of farming community in order to improve their quality of life through dissemination of knowledge. technologies, techniques, methods, ideas and useful information through extension system. It assists farm people. through educational process, in improving farm. production methods and techniques, increasing production efficiency and income, improving their levels of living and lifting the social and educational standard of rural life. Agricultural extension services, which encompass public and private sectors, NGOs, research and academic institutions and also the farmers, are the main forces in the processes of technology transfer. The info1 1 mation usually flows from researchers to extension agents and from extension agents to farmers in one direction. and from farmers to extension agents and then to the researchers, in the other direction. As such, agricllitural extension services, which are almost now more than one hundred years old, have become the most real life information system for technology transfer (Qamar. 1999). Technology transfer system has two streams. One flow from farms or farmers (production sites) to the research stations through extension activity and the other ·from research stations to the farmers through the extension activity (Haga, 1999). The above concept of extension is most commonly in vogue throughout the developing and developed countries. Especially in the countries where information technology is not yet well developed. the role of extension wor}{ers is very vital to implement the programs of extension. Agricultural extension activities in less developed countries mostly centered on the performance of the field extension worl{ers. As a result the governments of these countrie's emphasize more on human resource development and improvement of the organizational management through policy guidelines and law. The appendix tables 8 to 12 vide appendices 6 to 10 provide some global information about the number of extension organizations. methods of extension works being followed and the number of extension worl{ers serving in the public sectors.
Who Speaks for Islamic Family Law? Debates on Islamic Law Compilation (KHI) in Indonesia

Field: Social Sciences (Social Sciences)

Who Speaks for Islamic Family Law? Debates on Islamic Law Compilation (KHI) in Indonesia Dr. Sadari, S.H.I., M.S.I Abstract This article discusses a debate within the formulation of Islamic Family Law in Indonesia, especially the various figures behind. Involving in that case is how far the practice of law negotiation implemented to respond unsatisfied groups over the formulation offered within the formal legislation (UU Marriage Number. 1/1974 and Islamic Law Compilation [KHI]) or non-formal (Counter Legal Draft [CLD]-KHI and Laws Draft [RUU]-HMPA). A history noted that Islamic Family Law was featured with discourses and the dynamic of that development. These features were not coming from an empty space, but through a long discussion. The point of debate was divided into two aspects, theoretical and practical. Both of them were having different interest and as a representation of their own group. Authority‘s contestation has done between the state and Islamic scholars in responding the practice of polygene, interfaith marriage and unregistered marriage. Government‘s need to give a serious punishment for these practices was strongly abandoned by classical Islamic scholars. A different point of view is also happened between two Islamic organizations in Indonesia, namely Nahdlatul Ulama (NU) and Muhammadiyah. The root of the problem was coming from the different point of views in which NU tends to hold a traditional values and Muhammadiyah tends to hold modern values. Both of them were having the different approach in the formulation of Islamic Family law in Indonesia. In the implementation of Islamic family law in Indonesia, Islamic majority has an effort to control public space law through a hope that Islamic family law could survive within an Indonesian law. However, that effort wills not success in changing the landscape of State law without any negotiation process. This article investigates the development of Islamic family law in Indonesia, both in the process of development and the offered decisions. Further, this article also reveals the actors influenced the draft of law, from the process to the debate of formulation. Through using social historical approach, this article shows that conservatism is strongly influencing the decisions of Islamic Family Law in Indonesia. The proof of conservative behavior lied on the rejection over the decision of Islamic family law, even though various approaches have offered. Full Text: PDF DOI: 10.15640/jisc.v6n1a2
Scouting for alfalfa winter injury

Field: Agricultural and Biological Sciences (Life Sciences)

Mid- to late-March is the time producers should be inspecting alfalfa (and other perennial forage grasses and legumes) for spring recovery. The atypical weather this past fall and winter has led to considerable uncertainty about forage crop survival. Winter-dormant plants lose much of their cold hardiness during an extended period of warmer-than-normal air and soil temperatures, which is referred to as the January or February thaw.
Social Media Impact on Youth Depression

Field: Social Sciences (Social Sciences)

In the 21st century internet spread all over the world without limitations and challenges to the world community as every person is connected with globally & made strong community affairs.Social media network with sharing peoples' activities as photographs, videos or their status.In Sri lanka, most of the people join with face book as a social media network to search their old friends or keep in touch with new communities.According to human beings such activities are common, but there are disadvantages such as women using fb to fulfill their emptiness in their lives.As a woman she expects lots of things such as love, security & caring etc.They expect such things from their families and their husbands.But they do not get that satisfaction even from both as they wish.In that situation whoever they meet in their lives they believe them and treat very high thinking that this is the ultimate in their lives.Fb is a new introduction where god comes to their lives as love.Most love affairs are unbelievable, as boys start love affairs to spend their idle time with the playful memorable moments.The end of such girls' love affairs is the boys vanishing with unpredictable social affairs such as depression ect.A case study comprising a mixture of qualitative and quantitative research methods were carried out to establish the facts.As tools of this research interviews, questionnaires and observations were too used as online researches to determine the youth depression as an impact of face book in Sri lanka.
A 35 GHz monolithic MESFET LNA

Field: Engineering (Physical Sciences)

The design and fabrication of a state-of-the-art 35-GHz monolithic low-noise amplifier (LNA) is briefly described. The amplifier, with 6.5-dB gain, 4-dB noise figure, and 10-dBm power output at 1-dB gain compression, is based on a 0.25- mu m*200- mu m molecular-beam epitaxy (MBE)-grown MESFET. Device, circuit design, fabrication details, and test results are presented.< >
KARAKTERISTIK DAUN DAN RENDEMEN MINYAK ATSIRI LIMA JENIS TUMBUHAN KAYU PUTIH (Characteristicsof Leaf and Essential Oil Yield of Five Cajuput Tree Species)

Field: Agricultural and Biological Sciences (Life Sciences)

Leavessignifies as the most important part of cajuput-oil-producing tree species from which the corresponding oil is extracted. Dimensionof leaf vary among different genus and even among different trees within the same genus as well as within the same species. In relevant, this research aimed to look into the characteristics of the leaf and essential oil yield of the five cajuput-oil-producing tree species. Those investigated species consisted of red-flowered trees (white-flowered trees , and which altogether indigenously grew at Wasur National Park, in Merauke (Papua). From those five species, approximately 6 kg of fresh leaf was taken and prepared for the steam-distillation process to extract their cajuput oil. In total, there were about 120 pieces of leaves as sampled that represented the dimension of all those five species. Results shows that the leaves of exhibited the biggest dimension (length and width), while those of consecutively has the smallest length and had the smallest width. Leaves of afforded the biggest oil yield (1,43 %) and red-flowered trees had the smallest oil yield (<0,1 %).
The Clinical Outcome of 260 Pediatric ITP Patients in One Center

Field: Medicine (Health Sciences)

In the current study, clinical and laboratory findings and treatment modalities of children with acute and chronic immune thrombocytopenic purpura (ITP) were evaluated retrospectively. Our purpose was to determine clinical outcome of children with ITP and their responses to different treatment regimes. Total of 260 children with ITP were enrolled in the study. The mean age of patients was 76.8 ± 48.1 months. The therapy responses of high-dose methylprednisolone (HDMP; n = 134), standard dose methylprednisolone (n = 32), and intravenous immunoglobulin (IVIG; n = 15) treatments were similar. Two (0.8%) of the 260 ITP patients had intracranial bleeding. None of the patients died due to hemorrhage. Of all the patients with ITP, 191 (73.5%) completely resolved within 6 months after initiation of the disease and therefore they were diagnosed as acute ITP; 69 patients (26.5%) had progressed into chronic ITP. The therapy responses of HDMP, standard dose methylprednisolone, and IVIG treatments are similar.