jimnoneill/paper-to-field-training huggingface dataset:
Encrypt Medical Image using CSalsa20 Stream Algorithm

Field: Computer Science (Physical Sciences)

As a result of the tremendous development in the field of information technology and the internet and exposure to a flood of violations to circumvent and steal information organized and unorganized. The urgent need for the emergence of data protection technologies and data encryption techniques. As a result of the tremendous development in the field of information technology and the internet and exposure to a flood of violations to circumvent and steal information organized and unorganized. The urgent need for the emergence of data protection technologies and data encryption techniques one of these methods, The Salsa20 encryption stream and all of its reduced versions Salsa20 / 7 and Salsa20 / 12 are among the fastest stream ciphers today. In this paper, the Salsa20 method is therefore improved by adding a new variable by using chaos theory which can achieve faster propagation than the original Salsa20 and has been applied by encrypting medical images that need confidentiality because some patients do not want anyone to know about a disease so the patient’s medical data is encrypted and no one can access it. This method has been tested and measured with the original Salsa20 with a series of tests. Most tests show that the proposed messy salsa is faster than the original salsa.
ADVANCED F CLASS GAS TURBINES CAN BE A RELIABLE CHOICE FOR IGCC APPLICATIONS

Field: Energy (Physical Sciences)

With the increase in natural gas fuel prices, customer interest in IGCC plants is growing as an alternative to the traditional coal plants. Future IGCC plants are expected to be more efficient, use less water, produce significantly less emissions, and have the potential to be a lower cost solution to address future CO2 and Hg regulations compared to the direct coal fired steam plants. Since IGCC plants ’ availability is a widely documented industry concern, this paper will summarize how the integration of the Siemens SGT6-5000F (formerly W501F) into future 60 Hz IGCC plants will address this issue. Siemens has over 300,000 hours of successful IGCC gas turbine operating experience in the United States and Europe and has supplied a range of products for many of today’s IGCC plants. Currently in the Siemens 60 Hz natural gas based operating fleet, the SGT6-5000F gas turbine has the largest number of operating engines and the most cumulative operating hours. Several advancements to this frame have increased its power and efficiency while decreasing emissions and life cycle costs without impacting reliability. Development programs, including syngas combustion system testing, were initiated to verify the SGT6-5000F readiness for future IGCC applications. This paper addresses the results of the comprehensive development program initiated to allow syngas operation of the SGT6-5000F in IGCC applications while maintaining the gas turbine system’s availability and reliability at levels expected by the industry.
Expression of glypican 3(GPC3) in embryonal tumors

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Embryonal tumors, such as neuroblastoma, medulloblastoma and Wilms' tumor, have their peak incidence in the first 4 years of life. These neoplasias exhibit genetic and clinical heterogeneity, but little is known about their molecular pathogenesis. Application of the differential-display PCR approach led to the identification of a gene, glypican 3 (GPC3), that is differentially expressed in cancer cells. Expression of this gene is usually limited to fetal mesodermal tissue, and its inactivation has been found to be responsible for the X-linked Simpson-Golabi-Behmel overgrowth syndrome. Here, we show that GPC3 mRNA is present in several neuroblastomas and all Wilms' tumors tested to date but not in medulloblastoma. GPC3 was not expressed in normal kidney tissues obtained from the corresponding Wilms' tumor patients, suggesting that in these cancer cells expression was not repressed (or was activated). No correlation was found between expression of GPC3 and the known indicator of neuroblastoma prognosis MYCN mRNA. However, all samples that expressed GPC3 also expressed IGF-II, coding for a growth factor important in the survival and growth of many cancer types. Although the biological significance of this relationship remains unclear, our results suggest that GPC3 may be implicated in the development of embryonal tumors through a signaling pathway that appears to involve IGF-II.
RELATIONSHIPS HOMOCYSTEINE AND ARTERIAL STIFFNESS IN PATIENTS WITH H-TYPE ARTERIAL HYPERTENSION

Field: Medicine (Health Sciences)

Objective: The aim of our study was to evaluate the prevalence of hyperhomocystinemia in patients with mild to moderate hypertension, to investigate the relationship between hyperhomocystinemia with arterial stiffness. Design and method: In the study was included 40 patients with mild and moderate hypertension. Performed measurements of office SBP, DBP, (24AMBP), determination of pulse wave velocity in arteries of elastic (PWVel) and muscular (PWVm) types, central SBP, biochemical blood test with homocysteine. Homocysteine > = 10 μmol / l), the called H-type hypertension. Patients treatment mono-, dual or triple combination (telmisartane, amlodipine, hydrochlortiazide). All tests was performed before and after 6 month therapy. Statistical results was performed using the software IBM Statistics SPSS 21. Results: The mean age of patients was 55.85 ± 2.09 (26 – 74) years. The average body weight was 87.3 ± 2.77 kg. The average BMI is 29.41 ± 0.63 kg / m2. The average office SBP/DBP at the beginning of the study were 155.88 ± 1.63/92.60 ± 1.43 mm Hg. The average office heart rate 71.40 ± 1.29 beats / min. Mean 24 SBP/DBP monitoring were 139.37 ± 1.49/82.47 ± 1.84 mm Hg. The average daily heart rate 71.38 ± 1.32 beats / min. We found that at the beginning of the study, 75% (30 patients with mild and moderate hypertension) had elevated of blood homocysteine more than 10 μmol / l). PWV was associated after regression analyses with homocysteine. PWV el after treatment (r = 0,307, p = 0,001). PWV m after treatment (r = - 0,733, p = 0,001). Office SBP after treatment (r = 0,423, p < 0,001). Office DBP after treatment (r = - 0,675, p = 0,001). CKD-EPI after treatment (r = - 0,342, p = 0,005). BMI after treatment (r = 0,227, p = 0,026). Creatinine before treatment (r = -0,411, p = 0,003). Creatinine after treatment (r = 0,572, p = 0,011). Conclusions: Homocysteine associated with vascular stiffness, independent of the blood pressure reduction during treatment.
Spirituality in the Marine Corps

Field: Social Sciences (Social Sciences)

Abstract : In his address at Trinity College in June of 1941, General George C. Marshall warned, soldier's heart, the soldier's spirit, the soldier's soul are everything. Unless the soldier's soul sustains him, he cannot be relied on and will fail himself and his command and his country in the end. The Marine Corps stresses the physical, mental, and spiritual development of Marines. Required training ensures that Marines are tested physically and mentally, but rarely are Marines challenged to develop their spiritual foundation. In the absence of formal training, the commander alone bears the responsibility to ensure his Marines are attending to their spiritual needs. Commanders must be more proactive in their task of facilitating religion, which is the foundation for true spirituality. Few commanders would openly deny the importance of spirituality. This viewpoint, however, has not led to proactive actions to change the climate to one in which spiritual growth is not simply tolerated, but actually encouraged. Because of the contribution of spirituality, not only in the lives of individual Marines, but also towards mission accomplishment, commanders must do more to facilitate spiritual growth at all echelons within their command.
Can We Decouple GDP Growth from Environmental Deterioration?

Field: Environmental Science (Physical Sciences)

The challenge is to look for solutions. Experts can consider landscape or land use planning, agroecosystem diversity maintenance, or finding effective indicators for sustainable development as potential tools to decouple GDP growth from environmental deterioration. Today’s trends on natural resources and environment in Southeast Asia seem to show that high GDP equals high environmental deterioration. To decouple high GDP growth from environmental deterioration, policymakers, together with various sectors need to constitute working groups at various hierarchical levels from the grassroots to the policy arena. These working groups should respectively cover climate change mitigation and adaptation; reduced emission from deforestation; biodiversity, livelihood and food security; coastal resource management; water and land resources; sustainable education; health risk; and policy.
Investigating exchange, structural disorder and restriction in Gray Matter via water and metabolites diffusivity and kurtosis time-dependence

Field: Neuroscience (Life Sciences)

Water diffusion MRI is a very powerful tool for probing tissue microstructure, but disentangling the contribution of compartment-specific structural disorder from cellular restriction and inter-compartment exchange remains an open challenge. Here, we use diffusion MR spectroscopy (dMRS) of water and metabolites as a function of diffusion time in vivo in mouse Gray Matter (GM) to shed light on: which of these concomitant mechanisms dominates the MR measurements and with which specific signature. We report the diffusion time-dependence of water with excellent SNR conditions up to 500 ms. Water kurtosis decreases with increasing diffusion time, showing the concomitant influence of both structural disorder and exchange. Despite the excellent SNR, we were not able to identify clearly the nature of the structural disorder (i.e. 1D versus 2D/3D short-range disorder). Measurements of intracellular metabolites diffusion time-dependence (up to 500 ms) show opposite behavior to water, with metabolites kurtosis increasing as a function of diffusion time. We show that this is a signature of diffusion restricted in the intracellular space from which cellular microstructural features can be estimated. Finally, by comparing water and metabolites diffusion time-dependencies, we attempt to disentangle the effect of intra/extracellular exchange and structural disorder of the extracellular space (both impacting water diffusion only). Our results suggest a relatively short intra/extracellular exchange time (1-50 ms) and short-range disorder (still unclear if 1D or 2D/3D) most likely coming from the extracellular compartment. This work provides novel insights to interpret water diffusion time-dependent measurements in terms of the underlying GM microstructure and suggests that diffusion time-dependent measurements of intracellular metabolites may offer a new way to quantify microstructural restrictions in GM.
A novel method for automated assessment of megakaryocyte differentiation and proplatelet formation

Field: Medicine (Health Sciences)

Transfusion of platelet concentrates represents an important treatment for various bleeding complications. However, the short half-life and frequent contaminations with bacteria restrict the availability of platelet concentrates and raise a clear demand for platelets generated ex vivo. Therefore, in vitro platelet generation from megakaryocytes represents an important research topic. A vital step for this process represents accurate analysis of thrombopoiesis and proplatelet formation, which is usually conducted manually. We aimed to develop a novel method for automated classification and analysis of proplatelet-forming megakaryocytes in vitro. After fluorescent labelling of surface and nucleus, MKs were automatically categorized and analysed with a novel pipeline of the open source software CellProfiler. Our new workflow is able to detect and quantify four subtypes of megakaryocytes undergoing thrombopoiesis: proplatelet-forming, spreading, pseudopodia-forming and terminally differentiated, anucleated megakaryocytes. Furthermore, we were able to characterize the inhibitory effect of dasatinib on thrombopoiesis in more detail. Our new workflow enabled rapid, unbiased, quantitative and qualitative in-depth analysis of proplatelet formation based on morphological characteristics. Clinicians and basic researchers alike will benefit from this novel technique that allows reliable and unbiased quantification of proplatelet formation. It thereby provides a valuable tool for the development of methods to generate platelets ex vivo and to detect effects of drugs on megakaryocyte differentiation.
PENANGGULANGAN KEMISKINAN

Field: Social Sciences (Social Sciences)

Poverty is a very complex development issues. Poverty is seen as spillovers from development and part of the problem in development. The existence of poverty is characterized by unemployment, underdevelopment, and inequality between regions. Poverty is also indicated by the presence of slums and squatter, and the existence of groups of people categorized as poor families caused by the limitations of economic, social and political life of their poor families. This phenomenon is demonstrated by the presence of several heads of families who are economically unable to meet the primary needs of family members. In addition, low levels of public education also makes it difficult to obtain jobs with adequate results or provide for his family. There are also a number of families whose low level of health that is hindering their work. This paper would like to discuss the steps that can be taken by the government to tackle poverty masalahan. KEY WORDS:Poverty, Unemployment, Underdevelopmen, Inequality, Poor Family, Low Level of Education.
Comparison of Multi Criteria Decision Making Method (WP, SAW & TOPSIS) for best supplier selection.

Field: Decision Sciences (Social Sciences)

Purpose: This study aims to find the best method among the methods that have often been used in the selection of suppliers among the methods to be compared is the MCDM (WP, SAW &TOPSIS) method. Design/methodology/approach: Selecting the right supplier will significantly reduce the cost of purchasing materials and improve the competitiveness of the company. In Rouydel's research for supplier selection using 6 criteria that will be an assessment of supplier selection including: Quality, Price / cost, standardization, Service, Flexibility, On time delivery [8]. Findings/result: The results of this study are that the three WP, SAW and TOPSIS methods can be used in supplier selection, of the three methods almost all are equal in the ranking so it can be concluded that the three WP, SAW and TOPSIS methods are the right methods in the decision making of the best supplier selection. Originality/value/state of the art: The selection of the best suppliers in Indonesia rarely pays attention to the Flexibility factor when this factor is needed in the selection of suppliers, and on average only based on price, shipping, quality criteria.
The Forming Scheme of a Silencer Cover in Progressive Die

Field: Engineering (Physical Sciences)

Abstract. The drawing scheme of a silencer cover in the progressive die was studied. This cover was formerly processed by several single punching dies and now was produced by a progressive die. The drawing scheme was hard to determine. Therefore, the explicit dynamic software DYNAFORM was applied to make simulations about the drawing process. According to comparisons between the simulation and experiment results, the optimized drawing scheme, blank layout, blank size, binding force and some other process parameters were determined. The defects were eliminated after the proper drawbead was set. Experiments showed that numerical simulation provided an efficient way for the optimization of the forming scheme in the progressive die production.
Pulse radiolysis of aqueous eosin

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPulse radiolysis of aqueous eosinJohn Chrysochoos, J. Ovadia, and Leonard I. GrossweinerCite this: J. Phys. Chem. 1967, 71, 6, 1629–1636Publication Date (Print):May 1, 1967Publication History Published online1 May 2002Published inissue 1 May 1967https://pubs.acs.org/doi/10.1021/j100865a014https://doi.org/10.1021/j100865a014research-articleACS PublicationsRequest reuse permissionsArticle Views130Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
The Risk Factors of Recurrent Aphthous Ulceration among Patients in Misan Governorate

Field: Dentistry (Health Sciences)

Recurrent aphthous ulceration (RAU) is the most common oral mucosal disease which characterized by recurrent episodes of multiple or solitary painful ulcerations without association with systemic diseases. The objectives of our study were to investigate the relation of RAU to demographical, education level and smoking habit. The study was conducted on 120 patients, personal data (age, sex), site, level of education and smoking habit were taken. The results showed that females were affected more than males, the buccal mucosa and tongue (58 %, 24%) respectively were the most common site of occurrence. There was higher prevalence rate of RAU among patients with higher educational level (60%) and in non-smokers (93.3%)
Waste Heat Recovery and Reuse of Flue Gas in Copper Pyrometallurgy

Field: Energy (Physical Sciences)

In the paper, we take current relatively advanced, the most widely used flash smelting furnace, converter and rotary anode furnace as the examples, the waste heat resources of the process of matte smelting, the process of matte converting and the process of fire refining of blister copper in copper pyrometallurgy are analyzed respectively. Meanwhile, based on the way of using waste heat reasonably to suitable heat consumer in production process and the grade recovery principle of energy level matching, the model of waste heat recovery and reuse of flue gas in copper pyrometallurgy is constructed.
Cubic Transmuted Uniform Distribution: An Alternative to Beta and Kumaraswamy Distributions

Field: Mathematics (Physical Sciences)

In this article, a new cubic transmuted (CT) family of distributions has been proposedÂ by adding one more parameter. We have introduced cubic transmuted uniform (CTU) distributionÂ by using the proposed class. We have also provided a detail description of the statistical propertiesÂ of the proposed CTU distribution along with its estimation and real-life application.
Substance P Promotes Diabetic Corneal Epithelial Wound Healing Through Molecular Mechanisms Mediated via the Neurokinin-1 Receptor

Field: Medicine (Health Sciences)

Substance P (SP) is a neuropeptide, predominantly released from sensory nerve fibers, with a potentially protective role in diabetic corneal epithelial wound healing. However, the molecular mechanism remains unclear. We investigated the protective mechanism of SP against hyperglycemia-induced corneal epithelial wound healing defects, using type 1 diabetic mice and high glucose–treated corneal epithelial cells. Hyperglycemia induced delayed corneal epithelial wound healing, accompanied by attenuated corneal sensation, mitochondrial dysfunction, and impairments of Akt, epidermal growth factor receptor (EGFR), and Sirt1 activation, as well as decreased reactive oxygen species (ROS) scavenging capacity. However, SP application promoted epithelial wound healing, recovery of corneal sensation, improvement of mitochondrial function, and reactivation of Akt, EGFR, and Sirt1, as well as increased ROS scavenging capacity, in both diabetic mouse corneal epithelium and high glucose–treated corneal epithelial cells. The promotion of SP on diabetic corneal epithelial healing was completely abolished by a neurokinin-1 (NK-1) receptor antagonist. Moreover, the subconjunctival injection of NK-1 receptor antagonist also caused diabetic corneal pathological changes in normal mice. In conclusion, the results suggest that SP-NK-1 receptor signaling plays a critical role in the maintenance of corneal epithelium homeostasis, and that SP signaling through the NK-1 receptor contributes to the promotion of diabetic corneal epithelial wound healing by rescued activation of Akt, EGFR, and Sirt1, improvement of mitochondrial function, and increased ROS scavenging capacity.
Supplementary information from Balancing Efficacy and Safety of an Anti-DLL4 Antibody through Pharmacokinetic Modulation

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

<p>Supplemental Methods: including HUVEC fibrin gel bead assay, Production of anti-DLL4 F(ab')2, Mouse neonatal retina assay, Xenograft tumor models, Histological analysis of mouse liver, PK assay methods, and Anti-therapeutic antibody assay method. Table S1: PK parameters of anti-DLL4 IgG1 and F(ab')2 in mouse. Table S2: PK parameters for anti-DLL4 IgG1 and F(ab')2 in rat and money. Table S3: Summary of incidence of skin neoplasms in rats treated with anti-DLL4 IgG1 or anti-DLL4 F(ab')2. Figure S1: Generating and characterizing low affinity anti-DLL4 antibodies. Figure S2: Characterization of anti-DLL4 F(ab')2 using HUVEC bead sprouting assay. Figure S3: PK profile of anti-DLL4 IgG1 and F(ab')2 in rat toxicity studies. Figure S4. Mitigation of liver toxicity in mice with anti-DLL4 F(ab')2. Figure S5. Novel toxicities identified with anti-DLL4 F(ab')2 in rats.</p>
Soft Rot Disease Severity Is Affected by Potato Physiology and Pectobacterium taxa

Field: Agricultural and Biological Sciences (Life Sciences)

Pectobacterium species cause disease worldwide in many crop and ornamental plants, including potato. A new Pectobacterium subspecies, P. carotovorum subsp. brasiliensis was recently described in Brazil and later found in the United States, Israel, and South Africa. Its virulence traits and host range remain unknown. A comparison of three taxa commonly found on potato showed that both P. carotovorum subsp. carotovorum and subsp. brasiliensis are more aggressive in causing tuber and stem soft rot than P. atrosepticum. Also, despite bacterial growth inhibition in vitro of P. carotovorum subsp. carotovorum and P. atrosepticum strains by P. carotovorum subsp. brasiliensis, this new subspecies and P. carotovorum subsp. carotovorum are able to co-colonize in the same infected tissue. Both subspecies were motile in lesions. Pathogenesis assays showed that host ranges of all three overlap, but are not identical. The host ranges of individual strains of P. carotovorum subsp. carotovorum and subsp. brasiliensis are limited, whereas P. atrosepticum can macerate many plant species in addition to potato. There was high variability in virulence assays with potato tuber; thus physiological factors were investigated. Tuber size, maturity, and field location had significant effects on susceptibility to soft rot, with larger, more mature tubers being more susceptible.