jimnoneill/paper-to-field-training huggingface dataset:
Synthesis, Photooxygenation and DNA Studies of Novel Fused Furo, Dioxolo, and Dioxino Derivatives of Coumarin

Field: Chemistry (Physical Sciences)

Abstract Syntheses of novel fused furo, dioxolo and dioxino derivatives of coumarin are carried out through the reaction of 7,8‐dihydroxycoumarin derivative 1 with α‐halocarbonyl compounds (α‐haloketone, α‐haloester and chloroacetyl chloride) and 1,2‐dichloroethane. The photooxygenation of synthesized furocoumarin derivative was performed and the affinity of furocoumarin derivative towards DNA was evaluated and compared with 8‐methoxypsoralen (8‐MOP), which extensively used in photochemotherapy.
Benefits of a Nanosilver Nasal Spray for Postoperative Care of Patients with Chronic Rhinosinusitis

Field: Medicine (Health Sciences)

To explore tending to patients with chronic rhinosinusitis using a nanosilver compound. From February 2014 to August 2016, 112 surgical patients with chronic rhinosinusitis were randomly divided into an observation group and a control group. Patients in the observation group were given antibiotics, care to retain hemostasis, and other treatment after surgery. Patients in the observation group were administered treatment with bonbijing nano antibacterial water spray post-surgery. The progress of both groups recorded. Nanosilver is metallic silver of nanometer size. Nanosilver particles in the spray are approximately 25 nm in diameter, strongly inhibit growth of or kill dozens of pathogenic microorganisms, e.g., Escherichia coli . Postoperative pain in patients in the observation group was less than pain in the control group patients ( p < 0.05). Symptom and sign scores in observation group patients were lower than scores in control group patients ( p < 0.05). Incidence of adverse reactions and complications was also lower in observation group patients ( p <0.05). Use of nanosilver for tending to patients with chronic rhinosinusitis after surgery can significantly improve clinical symptoms and signs, and reduce adverse reactions and complications.
Development of a network visualization and analysis system for malignant tumors based on transcriptome data

Field: Computer Science (Physical Sciences)

Shiny technology has developed rapidly in recent years, as an R package for developing interactive app, through which we can package the written R code into a web app, which can not only save user time, but also accelerate the development of the speed of user-end communication, analyze the transcriptome data of related malignant tumors, and construct a ceRNA network diagram of desired malignant tumors. The code utilizing shiny technology package can facilitate users to map the ceRNA network associated with malignant tumors only through screen operation, significantly improving the efficiency and accuracy of clinical decision support in primary hospitals.
Laparoscopic appendicectomy: safe and useful for training.

Field: Medicine (Health Sciences)

Debate exists about the benefits of laparoscopic appendicectomy when compared to a conventional open procedure. The majority of appendices are removed by the open route in the UK. We report a series of 132 cases of suspected appendicitis managed laparoscopically: 112 (85%) of the patients had acute appendicitis, the remaining 20 (15%) had non-appendiceal pathology. The median operative time was 30 min and there were no conversions to an open operative procedure. The median postoperative stay was two days. Complications were seen in two patients. The published evidence comparing laparoscopic and open appendicectomy is contradictory. Our series shows that laparoscopic appendicectomy is a safe procedure with low morbidity; it is also an excellent training tool in laparoscopic technique and, with sufficient experience, takes no longer than an open procedure. Negative appendicocecotomies are most common in women of fertile age and can be associated with significant morbidity; therefore, laparoscopy should be used to make the diagnosis and, if appendicitis is the cause, the appendix could safely be removed laparoscopically. However, the choice between open and laparoscopic procedure is a subjective decision for the patient and their surgeon. Laparoscopic appendicectomy cannot be regarded as the gold standard.
Translating tuberculosis research into global policies: the example of an international collaboration on diagnostics

Field: Health Professions (Health Sciences)

Using the example of an international collaboration on tuberculosis (TB) diagnostics, we mapped the key stages and stakeholders involved in translating research into global policies. In our experience, the process begins with advocacy for high-quality, policy-relevant research and appropriate funding. Following the assessment of current policy and the identification of key study areas, policy-relevant research questions need to be formulated and prioritised. It is important that a framework for translating evidence into policy at the target policymaking level, in this case global, is available to researchers. This ensures that research questions, study designs and research standards are appropriate to the type and quality of evidence required. The framework may evolve during the period of research and, as evidence requirements may change, vigilance is required. Formal and informal multi-stakeholder partnerships, as well as information sharing through extensive networking, facilitate efficient building of a broad evidence base. Coordination of activities by an international, neutral body with strong convening powers is important, as is regular interaction with policy makers. It is recognised that studies on diagnostic accuracy provide weak evidence that a new diagnostic will improve patient care when implemented to scale in routine settings. This may be one reason why there has been poor uptake of new tools by national TB control programmes despite global policy recommendations. Stronger engagement with national policy makers and donors during the research-intopolicy process may be needed to ensure that their evidence requirements are met and that global policies translate into national policies. National policies are central to translating global policies into practice.
Carbon Dioxide Clathrate in the Martian Ice Cap

Field: Earth and Planetary Sciences (Physical Sciences)

Measurements of the dissociation pressure of carbon dioxide hydrate show that this hydrate (CO 2 ⋅ 6H 2 O) is stable relative to solid CO 2 and water ice at temperatures above about 121°K. Since this hydrate forms from finely divided ice and gaseous CO 2 in several hours at 150°K, it is likely to be present in the martian ice cap. The ice cap can consist of water ice, water ice + CO 2 hydrate, or CO 2 hydrate + solid CO 2 , but not water ice + solid CO 2 .
Bitter Laughter and Colonial Novellistica in Galeotto Cei’s Relazione delle Indie

Field: Arts and Humanities (Social Sciences)

The ornery prologue of Florentine merchant Galeotto Cei's travel account accurately sets the tone for the striking sixteenth-century narrative of a lengthy stay in the Americas. Cei, member of an exiled Florentine family, left for the Americas in 1539, engaged in trading activities and participated in Spanish expeditions into South American territories before returning to Europe fourteen years later. Certainly Florentine merchant Cei's Relazione delle Indie fits in well with a corpus of merchant writing. The context of the Decameron offers compelling points of comparison in examining Cei's text, in particular the role of the practical joke. As Giuseppe Mazzotta writes, in any discussion on laughter, the obvious point of reference is tragedy, and it, by comparison, seems all too accountable. If the noble youths' stories in the Decameron served as an antidote to the apocalyptic conditions of Florence during the 1348 plague, Cei's bitter comedy can be seen in relation to the horrific conditions he describes in the Americas.
Measuring e-Excise Tax Success Factors: Applying the DeLone

Field: Business, Management and Accounting (Social Sciences)

The rapid growth of e-Commerce amongst private sectors and Internet usage amongst citizens has vastly stimulated e-Government initiatives from many countries. The Thailand e-Government initiative is based on the government's long-term strategic policy that aims to reform and overhaul the Thai bureaucracy. This study attempted to identify the e-Excise success factors by employing the IS success model. The study focused on finding the factors that may contribute to the success of the e-Excise initiative. The Delphi Technique was used to investigate the determinant factors for the success of the e-Excise initiative. Three-rounds of data collection were conducted with 77 active users from various industries. The results suggest that by increasing Trust in the e-Government website, Perceptions of Information Quality, Perceptions of System Quality, and Perceptions of Service Quality will influence System Usage and User Satisfaction, and will ultimately have consequences for the Perceived Net Benefits.
Investment decision making by using fuzzy candlestick pattern and genetic algorithm

Field: Computer Science (Physical Sciences)

This paper proposed an approach to extract fuzzy candlestick patterns from financial time series and select a set of patterns for investment decision making. The candlestick chart in stock market is a widely used technical analysis model. The investor observes the candlestick chart and makes investment decisions by identifying patterns in the chart. We use fuzzy linguistic variables to model candlestick chart and extract patterns from the chart. A Genetic algorithm based approach is used to select a set of extracted pattern as the background knowledge in the system for investment decision making. The advantage of the proposed approach is the investment knowledge is comprehensible, editable, and visible. The user can set different range of historical financial time series to extract and select different set of patterns. The experimental results shows that the investment decisions based on selected fuzzy patterns have better investment performance than using original non-fuzzy patterns.
Low-cost manufacturing of flow channels with multi-nozzle abrasive-waterjets: a feasibility investigation

Field: Engineering (Physical Sciences)

Stamping and photochemical machining have been two of the common methods for manufacturing flow channels used in reformers, reactors, heat exchangers, and fuel-cell stacks. The flow channels are then bonded to form the finish products. These methods are severely constrainted by plate area and thickness, material type, and environmental concerns. Furthermore, they are too costly to meet the U. S. DoE's targeted goal - untaxed price of $2.00-3.00/gge (gasoline gallon equivalent). Abrasive-waterjets were applied for machining various flow-channel patterns such as high-espect-ratio slots/ribs on several metals and non-metals were conducted to demonstrate its merits over other machine tools.
Studies on the Rumen Fermentation

Field: Agricultural and Biological Sciences (Life Sciences)

1. 各種の飼養条件における山羊および緬羊の第一胃内容液について,発酵管を使用して,ガスおよび揮発性脂肪酸類(VFAs)生成能の日中変化を経時的に追跡し,また第一胃内容液のVFAs濃度の経時的変化をも検索した.2. 飼養条件のいかんを問わず,ガス生成能は,その変動の型として,採食後数時間で起こる第1のピークと16～18時間後に起こる第2の高位のレベルへの高まりとを示した.VFAs生成能の消長でも,同様の型がみられた.3. 性ガス生成能は,生牧草,サイレージ給与時に高いレベルを,また生野草,牧乾草給与時に低いレペルを示した.稲藁給与時には,ガス生成能とVFAs生成能は，いずれもとくに低かつた.4. 胃内のVFAs量は,いずれの飼養条件のもとでも,採食後10～12時間目に最高に達し,以後漸減して，24時間後にはほぼもとのレベルに復帰した．5. 発酵管を使用して測定すると,生成されたガス量と,その開に生成されたVFAs量との間に,正の相開が認められた.
The poynting effect in soft composite materials

Field: Materials Science (Physical Sciences)

The Poynting effect in soft homogenous cylinders under pure torsion as well as the inversion and perversion of soft homogenous cylinders under pure axial loading are studied. In the context of this project, the Poynting effect is described as the tendency for the cylinder to elongate or contract in axial direction when torsion is applied. Inversion refers to the point at which the elongation of the cylinder in the axial direct reaches a maximum point when under pure axial loading. Perversion refers to the point at which a change from elongation to contraction in the axial direction occurs under pure axial loading. The net change in the homogenous cylinder under torsion due to the Poynting is also studied. The project focuses on the theoretical aspects of the cylinder under pure torsion and pure axial loading through the application of second-order elasticity and Lagrangian equilibrium equations. Soft materials in the human body can exhibit the Poynting effect as well as inversion and perversion. Thus, soft material within cardiac papillary muscle analyzed along with soft gels and metals. Attention is given to the second-order and third order elastic constants that give rise to contraction in the axial direction or a negative Poynting effect when under torsion. It is found that a negative Poynting effect is typically seen in material with positive third-order elastic constants. Results also suggest a correlation between the negative Poynting effect and the inversion and perversion of the cylinder under pure torsion and pure axial loading respectively. It is also found that net change volume of the homogenous cylinder under pure torsion relates to the radial displacement associated with the Poynting effect.
Comparative Study Effect of Urea-Sulfur Fertilizers on Nitrogen Uptake and Maize Productivity

Field: Agricultural and Biological Sciences (Life Sciences)

Combined nitrogen (N) and sulfur (S) fertilization is a good management strategy to reduce N loss and increase the efficiency of N fertilizers to achieve high grain yields and quality. Field trials for 2 yrs. (2018–2019) were conducted to evaluate the comparative advantage of conventional urea (150 N kg ha−1) compared to urea+ ammonium sulfate (150 N kg ha−1), urea+ calcium sulfate (150 N kg ha−1), and urea cocrystals (CaSO4.4urea) (150 N kg ha−1) when applied as nitrogen fertilizers to the maize. The statistics show a significant treatments effect on developed corn cobs, fresh and dry cob yields and grain yield, with 1000 grains with better results in 2019 than in 2018. The fertilization treatments affected grain yields significantly for 2018 and 2019, respectively. Urea+ ammonium sulfate and urea cocrystal provided a significant increase in grain yields by 10.5% and 7.50%, respectively, compared to urea in 2018, w1hereas, in 2019, urea cocrystal supplied the grain yields with a significant increase of 23.07% compared to urea, followed by urea + calcium sulfate which provided a 10.46% increase compared to urea. The study highlights that using urea-sulfur fertilizers enhanced the release of mineral nitrogen in the soil, improved the grain’s N uptake by the plant and increased maize grain yields.
PREPARING DECISION REGARDING LAMPUNG SOLAR PRINTING BANNER MAKING SERVICES USING MARKETING MIX (7P)

Field: Business, Management and Accounting (Social Sciences)

A particular emphasis will be placed on the banner manufacturing service that Surya Printing Lampung offers to accomplish the purpose of this research, which is to investigate the influence of the promotion mix (7P) on the purchasing decision of consumers. A total of 96 samples, as part of this investigation, were used to perform multiple regression. The assistance of SPSS version 23 was used. According to the obtained regression analysis, factors such as value, position, location, and procedures, as well as physical evidence, have a favorable and significant impact through statistics on retail customers' purchasing decision. Off-product and people variables, on the other hand, do not provide evidence of such a link. While this is going on, the marketing mix (7P), which is determined by the F test, is affecting the decision to purchase banner manufacturing services from Surya Printing Lampung. Keywords: Purchasing Decision ;Marketing Mix (7P); Banner
KRAS Mutant Combination Therapy for the Effective Treatment of Cancer

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVPatent HighlightNEXTKRAS Mutant Combination Therapy for the Effective Treatment of CancerRobert B. Kargbo*Robert B. KargboUsona Institute, 277 Granada Drive, San Luis Obispo, California 93401-7337, United States*Email: [email protected]More by Robert B. Kargbohttps://orcid.org/0000-0002-5539-6343Cite this: ACS Med. Chem. Lett. 2021, 12, 10, 1517–1518Publication Date (Web):September 12, 2021Publication History Received29 August 2021Published online12 September 2021Published inissue 14 October 2021https://pubs.acs.org/doi/10.1021/acsmedchemlett.1c00466https://doi.org/10.1021/acsmedchemlett.1c00466editorialACS PublicationsCopyright © Published 2021 by American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views2454Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (691 KB) Get e-AlertscloseSUBJECTS:Cancer,Cells,Genetics,Inhibitors,Peptides and proteins Get e-Alerts
Making Tradition of an Ass. Zênôn the Alexandrian, a White Donkey, and Conversion to Hellenism

Field: Arts and Humanities (Social Sciences)

Abstract Modern discussions of religious change in the ancient Mediterranean have frequently focused on the steady increase in Christian authority and numbers, and the related decrease in the number of 'pagans.' This is frequently paired with a supercessionist logic that suggests Christianity is a new thing in contrast to the older, static, Jewish and pagan cultures. Looking at an invented conversion ritual (one moving from Judaism to Hellenism), we can begin to question the standard ideas of tradition and innovation in Late Antique religious cultures, and to see the ways that some Jews and Hellenes used Christian discourses to assert their own independence and agency.
What Can Outliers Teach Us About Entrepreneurial Success?

Field: Economics, Econometrics and Finance (Social Sciences)

Case studies of entrepreneurs and their startups offer detailed information on the process of creating a new enterprise, but are often unusual examples of entrepreneurial efforts at large. By developing a novel approach to outlier analysis, this paper seeks to combine inductive insights from such case studies with hypothetico-deductive perspectives that have typically been applied to more general samples of firms. The approach pairs the case-based identification of mechanisms that may lead to entrepreneurial success with robust statistical analysis of a comparison group of entrepreneurs that have been sampled irrespective of their performance or persistence. Following the iterative refinement of case-based mechanisms, repeated tests using the comparison data, and analysis of residuals and outlier diagnostics, the process of theoretical and empirical examination concludes once all hypotheses generated by a case study have been evaluated and the case does not exert undue influence on the conclusions that are being drawn. We illustrate our approach to outlier analysis using a prominent case from economic history: the House of Rothschild, which emerged in Frankfurt’s Jewish enclave during the 18th century and became the most famous investment bank in Europe.
Job and Health Implications of VDT Use: Initial Results of the Wisconsin-NIOSH Study

Field: Health Professions (Health Sciences)

<p>Magnitudes and correlates of stress were investigated among 248 office workplace VDT users and 85 nonuser counterpart using field survey and objective physical measurement technique. Other than a tenuous indication of increased eyestrain and reduced psychological disturbances among users, the two groups were largely undifferentiated on job- attitudinal, affective, and somatic manifestations of stress. However, aspects of working conditions were judged less favorable by VDT users. Stress mechanisms were much the same for both groups, involving psychosocial as well as physical environmental job attributes as Were Corrective Eyewear Use and Ambient Lighting for Visuo Ocular, For Vdt Users, The Chair and Workstation Configuration Were Particularly Important Predictors of Musculo Skeletal Disturbances as were Corrective Eyewear Use and Ambient Lighting for Visuo Ocular, For Vdt Users, The Chair and Workstation Configuration Were Particularly Important Predictors of Musculo Skeletal Disturbances</p>
Reinterpreting Exceptions to the Use of Force in the Interest of Security: Forcible Intervention by Invitation and the Demise of the Negative Equality Principle

Field: Social Sciences (Social Sciences)

This essay describes tensions that arise between two types of public goods enshrined in the United Nations Charter—the right to self-determination of people(s) within a territorial state and peace and security—in situations in which recognized governments in conflict-torn countries request military assistance from third states against opposition groups. It illuminates legal challenges in reconciling these public goods in practice, at a time when collective peacekeeping mechanisms appear unable to prevent or terminate civil conflicts and their destabilizing regional impact.
Stereochemistry of Phellinsin A: A Concise Synthesis of α‐Arylidene‐γ‐Lactones

Field: Chemistry (Physical Sciences)

Phellinsin A (1a) was prepared in a concise way, thereby elucidating the relative stereochemistry of the aryl and carboxylic acid groups in 1a. The synthesis employed selective monohydrolysis of the dilactones derived from oxidative dimerization of cinnamic acid derivatives. This approach provided a practical synthetic route to α-arylidene-γ-lactones.
Clonidine in the Treatment of Menopausal Symptoms

Field: Medicine (Health Sciences)

ABSTRACT Thirty‐seven women complaining of hot flushes, sweating and other menopausal symptoms were treated with clonidine. A double‐blind crossover trial with placebo controls was undertaken. The clonidine dose was 2 × 0.025 mg/24 hours–0.075 mg/24 hours, increased if necessary at intervals of two weeks. The effect of clonidine did not differ significantly from placebo effect in the treatment of the symptoms. Side effects during clonidine management were slight and no difference was seen in their incidence compared with that in the patients treated with the placebo. A definitive placebo response was perceivable in the decreasing of symptoms.