jimnoneill/paper-to-field-training huggingface dataset:
Video Profile Pemasaran Destinasi Wisata Arung Jeram Desa Rantau Nipis Kec. Banding Agung Oku Selatan

Field: Social Sciences (Social Sciences)

Rantau Nipis is a village located in the District of Banding Agung, South Ogan Komering Ulu Regency, South Sumatra, Indonesia. This village has a postal code of 32274. This village has a population of 1,391 people consisting of 696 men and 695 women. The population of Lime overseas includes various tribes, including the Ogan Tribe, the Semende Tribe, the Java Tribe and the Ranau Tribe. Most of the community's income is from agriculture and fishing. Rantau Jeruk Nipis Village includes tourist areas including white water rafting which is centered on a lake located in Rantau Jeruk Nipis Village, there is a play area for young people to relax, a micro power plant and other areas. Rantau Nipis Village is a village with great tourism potential. Rantau Nipis is a village that has a lot of tourism objects, tourism objects need to be explored and seen with the help of video recording facilities so that this village has audiovisual recordings or can be called videos to attract tourism for the community or visitors.
Addressing the Needs of Migrant Workers in ICUs in Singapore

Field: Health Professions (Health Sciences)

Background: With nearly 400 000 migrant workers in Singapore, many from Bangladesh, India and Myanmar, language and cultural barriers posed a great many challenges during the COVID-19 pandemic. This was especially so as majority of the COVID-19 clusters in Singapore emerged from their communal dormitories. With concerns arising as to how this minority group could be best cared for in the intensive care units, the need for medical interpreters became clear. Main: In response, the Communication and Supportive Care (CSC) workgroup at the Singapore General Hospital developed the ‘Medical Interpreters Training for ICU Conversations’ program. Led by a medical social worker-cum-ethicist and 2 palliative care physicians, twenty volunteers underwent training. The program comprised of 4 parts. Firstly, volunteers were provided with an overview of challenges within the COVID-19 isolation ICU environment. Discussed in detail were common issues between patients and families, forms of distress faced by healthcare workers, family communication modality protocols, and the sociocultural demographics of Singapore’s migrant worker population. Secondly, key practice principles and ‘Do’s/Don’ts’ in line with the ethical principles of medical interpretation identified by the California Healthcare Interpreters Association were shared. Thirdly, practical steps to consider before, during and at the end of each interpretation session were foregrounded. Lastly, a focus group discussion on the complexities of ICU cases and their attending issues was conducted. Targeted support was further provided in response to participant feedback and specific issues raised. Conclusion: As a testament to its efficacy, the program has since been extended to the general wards and the Ministry of Health in Singapore has further commissioned similar programs in various hospitals. In-depth training on the fundamentals of medical terminology, language and cultural competency should be provided to all pertinent healthcare workers and hospitals should consider hiring medical interpreters in permanent positions.
Utilization of MEA medium for isolation and characterization of white oyster mushroom (Pleurotus ostreatus) and growth assessment on baglog

Field: Agricultural and Biological Sciences (Life Sciences)

White oyster mushrooms (Pleurotus ostreatus) are widely cultivated in Indonesia. Oyster mushroom cultivation is one of the export commodities that help to meet food needs. Pleurotus sp. requires an appropriate environment for developing these mushrooms, utilizing suitable planting media. Oyster mushroom media can be straw media or sawdust media. South Sumatra oyster mushroom cultivation uses sawdust media for 57.90% of white oyster mushroom cultivation, and straw media as an alternative for 100% white oyster mushroom cultivation. This research was conducted at the Phytopathology Laboratory, Department of Plant Pests and Diseases, Plant Protection Study Program, Faculty of Agriculture, Sriwijaya University, Indralaya, South Sumatra. Oyster mushroom observations were conducted in Payakabung Village, Ogan Ilir Regency, Indralaya. The research method used in this study was purposive sampling method which was carried out with 40 glass bottles containing corn groats, bran, and acacia sawdust as oyster mushroom seed media observed for 5 days which were placed in an incubator (20-25 °C) and storage box (26-30 °C), as well as baglog making using sawdust from various types of wood, namely rubber sawdust (Control Treatment) and acacia sawdust (Treatment 2). The development of oyster mushrooms in the first stage is characterized by the formation of fruiting bodies with a length range of 6.5 cm and reaching a diameter range of 15 cm at 40 days. The stalks and hoods of oyster mushrooms are yellowish white. Average growth of oyster mushroom hyphae on MEA media. Observations showed that oyster mushroom isolates on MEA 1 media (fresh oyster mushroom fruiting bodies) had long hyphal growth, and MEA 2 (farmers› seeds) had fast hyphal growth.
A Systematic Review of Seven Core Quality Control Tools and Their Applications in Manufacturing Process Improvement

Field: Decision Sciences (Social Sciences)

This paper provides a comprehensive analysis of the seven basic quality control tools and their applications in addressing problems within manufacturing industries. The tools examined include cause-and-effect diagrams, check sheets, control charts, histograms, Pareto charts, scatter diagrams, and flowcharts. Each tool is discussed in detail, focusing on its purpose, theoretical foundations, and practical applications in quality management. The study emphasizes how these tools support systematic identification, analysis, and resolution of production challenges, thereby improving process efficiency, reducing defects, and enhancing overall product quality. By demonstrating their versatility and effectiveness, the paper highlights the relevance of these tools as essential components of continuous improvement strategies in modern manufacturing.
Dead Bones and Honest Wonders: The Aesthetics of Natural Science in Moby-Dick

Field: Arts and Humanities (Social Sciences)

Scholarship of the last 50 years has amply revealed the rich symbolic resources of the cetological chapters of Moby-Dick, as well as their complex engagements with questions of race, ethnology, and the nature of knowledge itself.1 Nevertheless, the relation of the chapters' natural science to Ishmael's aesthetic experience of the whale and the artistic project of the book as a whole has yet to be fully understood. This oversight has been the result of some common assumptions among readers: namely, that natural history and zoology are at odds with the book's artistic aims and that their empirical methods pose a threat to Ishmael's vision of a reality that transcends the sensible world. With only a handful of exceptions, Tyrus Hillway's claims that Melville denounced the "coldness and inhumanity of the scientific mind" and its "destruction of beauty" have lain largely untouched since he first made them in the 1940s (Hillway 1950, 411).2
Coastal Zone Canada Association: Carrying the Torch for Coastal and Ocean Management in Canada

Field: Social Sciences (Social Sciences)

Abstract The Coastal Zone Canada Association (CZCA) was formed in 1993 to promote integrated coastal and ocean management (ICOM) in Canada and the world. The first Coastal Zone Canada (CZC) conference was held in Halifax, Nova Scotia in 1994, and ever since the CZCA has carried the torch for ICOM in Canada through a series of biennial CZC conferences. Since the inaugural Halifax meeting, further CZC conferences have been held in 1996 in Rimouski, PQ, 1998 in Victoria BC, 2000 in Saint John NB, 2002 in Hamilton ON, 2004 in St. John's NL, 2006 in Tuktoyaktuk, NWT, 2008 in Vancouver, BC, and 2010 in Charlottetown, PEI. This article reflects on the contributions of the CZCA to ICOM. Each of the conference statements, declarations, calls for action, publications, and toolkits have helped advance the discussion about ICOM in Canada, in particular the importance of community engagement and education as fundamental to ensuring the success of ICOM policies and processes. Through its publications, networking, and the influence of its members, the CZCA has played its part in raising the profile of ICOM in Canada and internationally, and influencing the legislative and public policy agenda in Canada. Keywords: Canadacoastal and ocean managementCoastal Zone Canada AssociationCoastal Zone Canada conferences Acknowledgments Peter Ricketts was president of the CZCA, 2002–2008; Barry Jones was president of the CZCA, 1998–2002; Lawrence Hildebrand was chair/president of the CZCA, 1996–1998; Brian Nicholls was chair of the CZCA, 1994–1996; Grant Gardner is president of the CZCA, 2008–present. Notes 1. By courtesy of the Department of Fisheries and Oceans (DFO), Scotia-Fundy Region, the Association was provided office space at the Bedford Institute of Oceanography (BIO) in Dartmouth, NS, where it maintained its presence until 2009, when the office moved to Dalhousie University in Halifax, NS. 2. See http://www.pollutionprobe.org/managing.shared.waters, Managing Shared Waters: A Freshwater and Marine Coastal International Event, Conference Website (accessed November 7, 2010). 3. See http://www.pollutionprobe.org/managing.shared.waters/statement.htm (accessed November 7, 2010). 4. See http://www.czca-azcc.org/docs/CZC_2004_Statement.pdf (accessed November 7, 2010). 5. See http://www.czca-azcc.org/docs/TukDeclarationOfficial.pdf (accessed November 7, 2010). 6. See http://www.czca-azcc.org/docs/Tuk_summary.pdf (accessed November 7, 2010). 7. See http://www.czca-azcc.org/docs/FA_CZC08_stmt.pdf 8. See http://www.whitehouse.gov/files/documents/2010stewardship-eo.pdf 9. See http://www.gov.pe.ca/photos/original/FARD_ConfStmtEn.pdf
“My Jewish Gaberdine”

Field: Arts and Humanities (Social Sciences)

Two questions are involved in a discussion of “Jewish gaberdine”: First, what was a gaberdine? Second, what was the distinction in dress between Jew and Christian? Modern Shakesperean editors, confronted by the necessity of explaining gaberdine, quote the statements of the New English Dictionary , of previous editors, or of authors of costume books. The editors of the N.E.D. having found no reference to the word earlier than 1520, and none which gave an idea of the garment, fell back on the definitions in seventeenth-century dictionaries, which tell only half the story. Authors of costume books made compilations of quotations given in other costume books, and thus grew a definition which gained weight through sheer repetition. Most of these compilers cite the statements of Planché, but none of them quotes the sentence with which he concludes his discussion after examining the definitions of lexicographers and making deductions from literary references: “But, alas, we are no nearer to identification!” Any attempt at identification requires examination of the etymology of the word; definition and pictorial representation of the garments to which cognate terms in other languages were applied; contemporary evidence concerning materials of which gaberdines were made, and the rank of persons for whom they were made.
Control of Rta expression critically determines transcription of viral and cellular genes following gammaherpesvirus infection

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The replication and transcriptional activator (Rta), encoded by ORF50 of gammaherpesviruses, initiates the lytic cycle of gene expression; therefore understanding the impact of Rta on viral and cellular gene expression is key to elucidating the transcriptional events governing productive infection and reactivation from latency. To this end, the impact of altering Rta transcription on viral and cellular gene expression was studied in the context of a whole virus infection. Recombinant murine gammaherpesvirus (MHV)-68 engineered to overexpress Rta greatly accelerated expression of specific lytic cycle ORFs, but repressed transcription of the major latency gene, ORF73. Increased expression of Rta accelerated the dysregulation in transcription of specific cellular genes when compared with cells infected with wild-type and revertant viruses. A subset of cellular genes was dysregulated only in cells infected with Rta-overexpressing virus, and never in those infected with non-overexpressing viruses. These data highlight the critical role of Rta abundance in governing viral and cellular gene transcription, and demonstrate the importance of understanding how the relative expression of ORF50 during the virus life cycle impacts on these processes.
Minocycline Attenuates Lipopolysaccharide-Induced Locomotor Deficit and Anxiety-Like Behavior via Upregulation of the BDNF/CREB Protein Expression in the Rat Medial Prefrontal Cortex (mPFC)

Field: Neuroscience (Life Sciences)

Introduction: Neuroinflammation following lipopolysaccharide (LPS) administration induces locomotor deficit and anxiety-like behavior. In this study, minocycline was compared to memantine, the NMDA receptor antagonist, for its effects on LPS-induced locomotor deficit and anxiety-like behavior in rats. Methodology: Adult male Sprague Dawley rats were administered either two different doses of minocycline (25 or 50 mg/kg/day, i.p.) or 10 mg/kg/day of memantine (i.p.) for 14 days four days prior to LPS (5 mg/kg, i.p.) injection. The locomotor activity and anxiety-like behavior were assessed using the open field test (OFT). The phosphorylated tau protein level was measured using ELISA while the expression and density of brain-derived neurotrophic factor (BDNF) and cAMP response element-binding protein (CREB) protein in the medial prefrontal cortex (mPFC) were measured using immunohistochemistry and western blot, respectively. Results: In the mPFC, minocycline treatment reduced the locomotor deficit and anxiety-like behavior, reduced phosphorylated tau protein level, and upregulated BDNF/CREB protein expression comparable to memantine, with the higher dose of minocycline having better benefits. Conclusion: Minocycline treatment attenuated LPS-induced locomotor deficit and anxiety-like behavior in rats, possibly via a decrease in phosphorylated tau protein levels and an increase in the expression of the BDNF/CREB proteins.
Evolutionary and Structural Constraints Influencing Apolipoprotein A-I Amyloid Behaviour

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Apolipoprotein A-I (apoA-I) has a key function in the reverse cholesterol transport mediated by the high density lipoprotein (HDL) particles. However, aggregation of apoA-I single point mutants can lead to hereditary amyloid pathology. Although several studies have tackled the biophysical and structural impacts introduced by these mutations, there is little information addressing the relationship between the evolutionary and structural features that contribute to the amyloid behavior of apoA-I. We combined evolutionary studies, in silico mutagenesis and molecular dynamics (MD) simulations to provide a comprehensive analysis of the conservation and pathogenic role of the aggregation-prone regions (APRs) present in apoA-I. Sequence analysis demonstrated that among the four amyloidogenic regions described for human apoA-I, only two (APR1 and APR4) are evolutionary conserved across different species of Sarcopterygii. Moreover, stability analysis carried out with the FoldX engine showed that APR1 contributes to the marginal stability of apoA-I. Structural properties of the full-length apoA-I model suggest that aggregation is avoided by placing APRs into highly packed and rigid portions of its native fold. Following we set up to study the effect of natural mutations on protein conformation and stability. Compared to natural silent variants extracted from the gnomAD database, the thermodynamic and pathogenic impact of apoA-I amyloid mutations showed evidence of a higher destabilizing effect. MD simulations of the amyloid variant G26R evidenced the partial unfolding of the alpha-helix bundle with the concomitant exposure of APR1 to the solvent and the formation of beta-sheet segments at the C-terminus of apoA-I, giving a possible hint about the early steps involved in its aggregation. Our findings highlight APR1 as a relevant component for apoA-I structural integrity and emphasize a destabilizing effect of amyloid variants that leads to the exposure of this region. This information contributes to our understanding of how apoA-I, with its high degree of structural flexibility, maintains a delicate equilibrium between its monomeric native structure and intrinsic tendency to form amyloid aggregates. In addition, our stability measurements could be used as a proxy to interpret the structural impact of new mutations.
Potentiation of cis‐Diammine(1, 1‐cyclobutanedicarboxylato)platinum(II) by Amphotericin B in BALB/c Nude Mice Bearing Human Ovarian Carcinoma Cells

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Human ovarian carcinoma cells (HRA) were sensitized to cis ‐diammine(l, l‐cyclobutanedicarboxylato)platinum(II) (CBDCA) 1.2‐, 2.1‐ and 3.4‐fold by treatment with amphotericin B (AMB) at concentrations of 2.1, 5.4, and 10.8 μM , respectively. Moreover, the intracellular accumulation of platinum after 2‐h exposure to CBDCA was increased significantly by AMB treatment. For estimating the enhancing effect of AMB on CBDCA cytotoxicity in vivo , we prepared HRA cell‐inoculated nude mice. Ascites was evident 7 to 9 days after intraperitoneal (i.p.) inoculation of HRA cells, and the mice died of intraabdominal carcinomatosis 11 to 14 days (mean survival time (MST): 12.0±1.0 days) after inoculation. Treatment with AMB (2.0 mg/kg) alone increased the MST by only 1.2 days. Simultaneous treatment with CBDCA (12 or 15 mg/kg) and AMB (0.5 to 2.0 mg/kg) produced a significant increase in MST compared to treatment with CBDCA alone. Maximal MST (38.5 days) was obtained by treatment with 15 mgAg CBDCA plus 2.0 mg/kg AMB, whereas the MST with 15 mg/kg CBDCA alone was 15.8 days. A drug accumulation study demonstrated that platinum accumulation in tumor tissues after i.p. treatment with CBDCA and AMB in tumor‐bearing nude mice was increased significantly compared to treatment with CBDCA alone. These findings indicate that intraperitoneal combination chemotherapy with CBDCA and AMB is useful in nude mice with advanced ovarian carcinoma.
On “Methodological Monism” in Rural Sociology1

Field: Social Sciences (Social Sciences)

Abstract This paper is a brief outline of the history of methods in rural sociology which suggests that the dominant methodological practice results from institutional arrangements and the traditions of the academic culture, as well as commitment to a scientific sociology. I note oft‐stated critiques of the positivist model relevant to rural sociology's “methodological monism,” including imprecise measurement, low levels of predictability, and a social psychological orientation. I suggest, in addition, that methodological homogeneity in rural sociology presents social life as social facts rather than social process, leads to a simplistic understanding of the interview, and separates the researcher from the experience of research. A wider methodological orientation would, I suggest, encourage the examination of a wider range of issues and encourage wider participation in a subdiscipline which, because of its particular history, has developed in isolation from mainstream sociology.
Fulfilling the responsibility to protect

Field: Social Sciences (Social Sciences)

In this paper I argue that the present global institutional structure—founded and upheld by the international community—systematically violates human rights. In recent years the Responsibility to Protect (R2P) doctrine has emerged as a justification for the resolution of humanitarian crises. R2P is an approach to humanitarian crises that emphasizes the responsibilities that powerful international actors have to protect human rights. In this paper I seek to examine the moral structure of the R2P at the intersection between the literature on R2P, global justice, and global poverty (particularly the work of Thomas Pogge). I introduce and defend a new principle, which extends R2P. My claim, here, is that in order to fulfill (my extended version of) R2P, members of the international community must also—in addition to mitigating cases of humanitarian crises—stop systematically violating human rights themselves. The maintenance of the present global institutional architecture is, I argue, a daily violation of R2P. The connective moral analysis that I will put forward between the global institutional architecture, global poverty and R2P is, I hope, a novel approach. It is also strategic. Whilst the international community has shown willingness to intervene in situations of humanitarian crisis, it has not shown a similar commitment to remedying global poverty. By arguing, as I do in this paper, that alleviating global poverty is in fact a necessary component of fulfilling R2P, I hope to establish a preliminary ground for showing that the moral demands of R2P are much greater than they are presently treated, and that the doctrine includes demands to conduct mass institutional reform towards the actual protection of human rights.
Effect of vitamin B6 on lenses of diabetic rats.

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Vitamin B6 is essential for the metabolism of fat, carbohydrate and protein. In this study the effect of vitamin B6 on diabetes induced impairments in rat lenses was investigated. Although macroscopic examination revealed no opacification of rat lenses in any groups, uncontrolled induced diabetes caused significant decreases in lens glutathione and increases in lens protein nonenzymatic glycosylation and blood glucose. Administration of vitamin B6 did not inhibit these diabetes induced alterations significantly. SDS-polyacrylamide gel electrophoresis revealed some significant differences in some protein bands between groups.