jimnoneill/paper-to-field-training huggingface dataset:
Fat Grafting following Internal Tissue Expansion: An Option for Breast Reconstruction after Total Mastectomy

Field: Medicine (Health Sciences)

Background: Breast reconstruction is currently performed as standard practice. Methods: A prospective study was performed of patients after total mastectomy who underwent autologous breast reconstruction with fat grafting (FG) combined with internal tissue expansion between September 2015 and December 2020. The patients were classified into groups A to F depending on the steps of breast reconstruction. Groups A and B described patients with completed breast reconstruction with FG and expander removal, with or without nipple/areola complex reconstruction. C described patients during deflation of the expander combined with simultaneous FG. D described patients after expander implantation and refilling. E described patients after first FG, and F included patients who discontinued reconstruction with the described method and converted to reconstruction with a breast implant. Results: Among 22 treated patients‚ two were after first FG (9.09%‚ group E), two were after expander implantation and refilling (9.09%‚ group D), three were during deflation of the expander combined with simultaneous FG (13.63%‚ group C), and four (18.18%) had completed breast reconstruction—two (9.09%) without NAC reconstruction and symmetrization (group B) and two (9.09%) with completed breast reconstruction (group A). In 11 patients (50%), breast reconstruction was abandoned after expander implantation and one to three FG procedures (group F), converting to breast reconstruction with a breast implant. Conclusions: This study demonstrated successful breast reconstruction using FG and expander implantation. Breast reconstruction using this method is safe and enables possible abandonment at any treatment stage, as well as conversion to breast reconstruction with implants.
A comparison of intermittent vs. continuous and of adriamycin vs. methotrexate 5-drug chemotherapy for advanced breast cancer A Cancer and Leukemia Group B study

Field: Medicine (Health Sciences)

The therapeutic effectiveness of intermittent vs. continuous combination chemotherapy and of the substitution of adriamycin for methotrexate in a 5-drug regimen was evaluated in women with metastatic breast carcinoma. Patients were randomly allocated to receive continuous therapy with cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, prednisone ( CMFVP -C, 86 patients), intermittent CMFVP ( CMFVP -I, 109 patients), or intermittent CAFVP (107 patients). The CR + PR rate with CAFVP (71%) was superior to CMFVP -C (50%, p = 0.003) and to CMFVP -I (50%, p = 0.002). The remission duration with CAFVP (14 months, median) was superior to CMFVP -I (7 months) (p less than 0.01), and tended to be superior to CMFVP -C (9 months) (p = 0.07). There was a survival advantage of CAFVP (19 months, median) over CMFVP -I (13 months) (p = 0.01), but not over CMFVP -C (16 months) (p = 0.24). Among CR + PR patients, the survival with CAFVP (29 months, median) was superior (p = 0.02) to both CMFVP -I (18 months) and CMFVP -C (21 months). The CMFVP -C regimen was associated with the highest incidence of leukopenia and neurologic toxicity, but the lowest incidence of GI toxicity. The results indicate that the CAFVP regimen is well tolerated and is superior to the CMFVP regimens.
Penentuan Kadar Karbohidrat pada Biji Cempedak Hutan (Artocarpus champeden Lour.) dengan Metoda Tembaga-Iodometri

Field: Agricultural and Biological Sciences (Life Sciences)

Forest Cempedak Seeds (Artocarpus champeden Lour.) Are types of seeds that are underutilized by humans. Forest Cempedak Seed Flour has nutritional content of carbohydrates, fats, and proteins that can be processed as ingredients for food. This study aims to determine the carbohydrate content of Forest Cempedak Seeds (Artocarpus champeden Lour.) Conducted by the Copper-Iodometric method using a luff schoorl reagent. From the research that has been carried out obtained levels of carbohydrates in Cempedak Seeds (Artocarpus champeden Lour.) of 38.016%.Â
Compression Molded Soy Protein Films with Exopolysaccharides Produced by Cider Lactic Acid Bacteria

Field: Agricultural and Biological Sciences (Life Sciences)

Two exopolysaccharide (EPS)-producing lactic acid bacteria (LAB) strains, Liquorilactobacillus (L.) sp CUPV281 and Liquorilactobacillus (L.) mali CUPV271, were isolated from Spanish apple must. Each of the strains produced a dextran, with different branching degrees, to be incorporated into soy protein isolate (SPI) film-forming formulations. Films were prepared by compression molding, a more rapid processing method than solution casting and, thus, with a greater potential for scaling-up production. Thermal analysis showed that SPI and EPS start the degradation process at temperatures above 190 °C, confirming that the compression temperature selected (120 °C) was well below the corresponding degradation temperatures. Resulting films were transparent and homogeneous, as shown by UV-Vis spectroscopy and SEM, indicating the good compatibility between SPI and EPS. Furthermore, FTIR analysis showed that the interactions between SPI and EPS were physical interactions, probably by hydrogen bonding among the polar groups of SPI and EPS. Regarding antifungal/fungistatic activity, LAB strains used in this study showed an inhibitory effect on germination of fungal spores.
The Development of Dyes and Methods for Dyeing Polyester

Field: Chemical Engineering (Physical Sciences)

Early work on the dyeing of polyester fibre showed that only dyes of very low aqueous solubility had substantivity for the fibre, and that for dyeing at the boil without a carrier only the smallest molecular weight disperse dyes, and selected azoic combinations, had sufficiently high dyeing rate to give adequate colour yield in a practicable time of dyeing. The development of carriers for dyeing at the boil, and of machinery for batchwise dyeing under pressure at temperatues up to 140°C, extended the range of suitable dyes to those of lower dyeing rate but higher heat–fastness properties. As an alternative to exhaust dyeing, polyester may be dyed with disperse dyes by padding followed by dry heat fixation at temperatures up to 220°C, and this method has found its main commercial application in the continuous dyeing of polyester–cellulosic blend fabrics. The development of new disperse dyes has followed these trends in application methods, and the proportion of available dyes having higher heat–fastness properties has steadily increased from about 1950 onwards. Improvements have also taken place over the same period in the physical properties of the dyes, to meet the increasingly severe demands on dispersion properties imposed by the newer dyeing methods.
A self oscillating class D audio amplifier with 0.0012% THD+N and 116.5 dB dynamic range

Field: Engineering (Physical Sciences)

A low distortion third-order self-oscillating class D audio amplifier is integrated in a 0.7-µm CMOS process. It can deliver 1.4 W into an 8 Ω load with 5 V power supply. The presented amplifier eliminates the requirement for a high quality carrier. It achieves a dynamic range (DR) of 116.5 dB, and a peak THD+N of 0.0012% for a 1 kHz sinusoidal input. The efficiency is 84.5%. The area of the amplifier is 6 mm 2 .
Active-Site-Directed Chemical Tools for Profiling Mitochondrial Lon Protease

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Lon and ClpXP are the only soluble ATP-dependent proteases within the mammalian mitochondria matrix, which function in protein quality control by selectively degrading misfolded, misassembled, or damaged proteins. Chemical tools to study these proteases in biological samples have not been identified, thereby hindering a clear understanding of their respective functions in normal and disease states. In this study, we applied a proteolytic site-directed approach to identify a peptide reporter substrate and a peptide inhibitor that are selective for Lon but not ClpXP. These chemical tools permit quantitative measurements that distinguish Lon-mediated proteolysis from that of ClpXP in biochemical assays with purified proteases, as well as in intact mitochondria and mitochondrial lysates. This chemical biology approach provides needed tools to further our understanding of mitochondrial ATP-dependent proteolysis and contributes to the future development of diagnostic and pharmacological agents for treating diseases associated with defects in mitochondrial protein quality.
The relationship between the MTA1 and nm23-H1 expression with biological behavior in Hazak′s esophageal cancer

Field: Medicine (Health Sciences)

Objective To investigate the expression significance of MTA1 and nm23-H1 gene and the relationship between MTA1 and nm23-H1 gene expressions of the effect of biological behavior in Hazak′s esophageal cancer.Methods Western blot was used to detect the expressions of MTA1 and nm23-H1 protein among 20 Hazak′s esophageal cancer samples.Results The positive rate of MTA1 proteins was 45% and there was no significant differences of expression between cancer tissues and normal tissues.But the negative expression of nm23-H1 proteins reached to 50%,moreover,the rate of intramuscular infiltration was 90%,which 70% samples were accompanied by lymph node metastasis.Conclusion Our finding suggests that MTA1 expression may not play an important role in infiltration and lymph node metastasis in Hazak′s esophageal cancer.The low expression of nm23-H1 protein may contribute to infiltration and lymph node metastasis in the biological behavior of Hazak′s esophageal cancer.And nm23-H1 can be used as a prognostic marker for detection of recurrence and metastasis in patients with esophageal cancer.
Echocardiography in differentiating tuberculous from chronic idiopathic pericardial effusion: Figure 1

Field: Neuroscience (Life Sciences)

Abstract

Cerebrospinal fluid (CSF) flows through the brain, transporting chemical signals and removing waste. CSF production in the brain is balanced by a constant outflow of CSF, the anatomical basis of which is poorly understood. Here we characterized the anatomy and physiological function of the CSF outflow pathway along the olfactory sensory nerves through the cribriform plate, and into the nasal epithelia. Chemical ablation of olfactory sensory nerves greatly reduced outflow of CSF through the cribriform plate. The reduction in CSF outflow did not cause an increase in intracranial pressure (ICP), consistent with an alteration in the pattern of CSF drainage or production. Our results suggest that damage to olfactory sensory neurons (such as from air pollution) could contribute to altered CSF turnover and flow, providing a potential mechanism for neurological diseases.
Influence of dynamic factors on calculating cumulative low back loads

Field: Health Professions (Health Sciences)

This study examined the error induced in estimating cumulative low back loading for exposure to dynamic manual materials handling tasks by using either static or quasi-dynamic biomechanical models when compared to a dynamic model. Ten male subjects performed three sagittal plane lifting tasks at three different lifting speeds and using three different hand loads. Digitized video recordings and measured hand forces were collected in order to calculate cumulative L4/L5 spinal loading (compression, moment, joint shear, and reaction shear) using rigid link and single muscle equivalent biomechanical models. Cumulative loading was calculated using three modeling approaches: static, quasi-dynamic, and dynamic. The calculation of cumulative loading using the dynamic model was set as the "gold standard" and error in the static and quasi-dynamic approaches was determined by comparison with the dynamic model. The use of a quasi-dynamic model resulted in an average error of −2.76% across all 10 subjects, 3 tasks, 3 lifting speeds and 3 masses. The static model had an average error of −12.55%. The error in both modeling approaches was significantly effected by the type of task performed, mass lifted, speed of lift, and model variable examined indicating that neither model produced consistent errors across the lifting parameters. The small errors associated with the quasi-dynamic model indicates that it holds promise as a method to reduce the amount of data required to estimate cumulative loading yet still preserve the dynamic loading exposure of a manual materials handling task.
East European Jews in Two Worlds: Studies from the YIVO Annual. Ed. Deborah Dash Moore. Evanston: Northwestern University Press and the YIVO Institute For Jewish Research, 1990. 334 pp.

Field: Arts and Humanities (Social Sciences)

East European Jews in Two Worlds: Studies from the YIVO Annual. Ed. Deborah Dash Moore. Evanston: Northwestern University Press and the YIVO Institute For Jewish Research, 1990. 334 pp. - Volume 53 Issue 4
Three Cases of Weil's Disease

Field: Medicine (Health Sciences)

instance no other drug was administered, no intercurrent disease could be demonstrated, and the original infection, pertussis, tends to produce leucocytosis and not agranulo- cytosis.A primary aplastic blood condition unrelated to drug therapy can occur but is a comparative rarity.In the present case hepatiJis and aplastic anaemia occurred' together, suggesting a single aetiological toxic agent, and hence, on the basis of this criterion and the fact that well- authenticated cases of aplastic anaemia following chlor- amphenicol administration have already been recorded, this drug would seem to be incriminated as the cause of aplastic anaemia.At the time of writing 19 cases, both adults and children, with granulocytopenia or aplastic anaemia following chlor- amphenicol therapy have been noted in the American litera- ture, and of these 11 have been fatal.In the first nine cases recorded, bone-marrow changes appeared after prolonged administration of the drug.In the mbst recent reports all 10 patients received short but repeated courses of the drug and came to a fatal termination (see Table ).The incidence 19 Cases of Bone-marrow Depression Following Chioramphenicol Therapy Age of To~uta
Extractable Organic Carbon and its Differentiation by Polarity in Diesel Exhaust, Wood Smoke, and Urban Particulate Matter

Field: Chemistry (Physical Sciences)

In order to determine whether characterization of organic carbon (OC) in particulate matter (PM) is limited due to the extraction or analysis, we have evaluated the OC extractability from three model PM matrices (wood smoke, diesel exhaust, and urban PM). We have compared hot pressurized water (HPW) fractionation and sequential organic solvent Soxhlet extraction. The evaluation of extraction efficiency was based on three methods: thermal optical transmittance (TOT), reflectance, and total organic carbon analyses. For all three PM samples, comparable OC yields were obtained with both extraction methods accounting for ∼45–60% of the total OC found in PM (based on TOT). These recoveries also suggest that a significant portion of OC in all PM materials remains unextractable.
Further investigation of OC distribution in different polarity fractions using spectrometric techniques (including gas chromatography with mass spectrometry, carbon 1s near-edge X-ray absorption fine structure, and proton nuclear magnetic resonance spectroscopies) revealed that sequential extraction may be useful approach to differentiate the constituents attributed to primary emission sources and to secondary aerosol formation, respectively. In contrast to the common expectation that polarity of constituents corresponds to the polarity of the extracting solvent, distribution of OC species (among the different polarity fractions) also depended on their availability (i.e., analyte-matrix interactions). It appears that secondary OC species (e.g., diacids) are not deeply embedded into the matrix, and thus were recovered in the solvent of a corresponding polarity. By contrast, primary OC constituents are strongly bound to the matrix and thus required harsh conditions to be recovered.
Bending Failure Behavior of Thin-walled Composite Tube Structures

Field: Materials Science (Physical Sciences)

Abstract The bending failure, failure load and failure mode of thin-walled circular tubes made of carbon fiber reinforced resin matrix composites were investigated by experiments and numerical simulation. Three typical failure modes of circular tubes under bending load were observed in experiments, and the characteristics and mechanisms of different failure modes were analyzed. The results show that interlaminar shear induces the generation and propagation of microcracks at the interface of circular tubes, which accelerates the failure of circular tubes. In the bending failure process, because the interlayer performance of the round pipe is relatively low, it is the weak link of the structure, and the pipe wall is the first to produce interlayer delamination and splitting failure under the action of shear stress, resulting in structural instability and premature fracture failure. The lay-up and initial defects of thin-walled round pipe have great influence on the bending failure mode and failure load.
Demographic Targeting of Internet Advertising

Field: Computer Science (Physical Sciences)

Thanks to its wide range of targeting, Internet has become a very attractive medium for advertisers. Although the current technologies can collect data about an individual's online activities and utilize it for a precise targeting, the traditional way of targeting based on affinity is still widely used. The goal of this paper is to evaluate the possibility of the traditional way of demographic targeting by gender and age on the Czech Internet thorough data mining of NetMonitor database. Research findings show that, in certain cases, traditional affinity-based ad targeting can be effective. This is especially true when targeting men and younger users. On the other hand, this method also generates wasted ad impressions outside the target group. This is particularly problematic when targeting elderly users. Modern techniques of ad targeting which are based on tracking users' activities are likely to further expand.
Coordinated control strategy of a DC grid with energy storage system

Field: Energy (Physical Sciences)

DC grid has a prospect of application in collecting and transmitting large‐scale renewable energy over long distance. However, the randomness and fluctuation of the renewable power may hamper the stable operation of DC grid. Energy storage device is able to actively absorb or supplement active power, which can be used to smooth the power fluctuation. The paper investigates a DC grid topology with energy storage and proposes a coordinated control strategy. The proposed strategy enables coordinated control of the renewable energy output power, pumped storage power and the grid consuming power. During the steady state, the control strategy enables the system DC voltage stable and power flow of the grid under zero‐error control. During the faulted time, the coordinate control strategy enables the converter fast response and maintains the system DC voltage within safety margin. The effectiveness of the coordinated control strategy is verified by simulation in PSCAD/EMTDC.
A 3D-Schroedinger operator under magnetic steps with semiclassical applications

Field: Physics and Astronomy (Physical Sciences)

We define a Schrödinger operator on the half-space with a discontinuous magnetic field having a piecewise-constant strength and a uniform direction. Motivated by applications in the theory of superconductivity, we study the infimum of the spectrum of the operator. We give sufficient conditions on the strength and the direction of the magnetic field such that the aforementioned infimum is an eigenvalue of a reduced model operator on the half-plane. We use the Schrödinger operator on the half-space to study a new semiclassical problem in bounded domains of the space, considering a magnetic Neumann Laplacian with a piecewise-constant magnetic field. We then make precise the localization of the semiclassical ground state near specific points at the discontinuity jump of the magnetic field.
危重症患者血清肿瘤坏死因子-α、白细胞介素-6及白细胞介素-10变化的研究

Field: Medicine (Health Sciences)

目的探讨危重症患者的血清肿瘤坏死因子-α（TNF-α）、白细胞介素-6（IL-6）、白细胞介素-10（IL-10）的变化，为判断危重症患者病情的严重程度提供新的客观指标。方法41例危重症患者中好转或治愈30例为存活组，死亡11例为死亡组，健康体检者20例为对照组。患者入住ICU后第1、7天清晨空腹抽取静脉血3ml，对照组抽空腹静脉血3ml，应用双抗体夹心酶联免疫吸附法检测血清中TNF-α、IL-6和IL-10的浓度。同时按急性生理和慢性健康评分系统（APACHEⅢ评分）方法进行危重症评分。结果危重症患者早期血清中促炎因子TNF-α、IL-6及抗炎因子IL-10的浓度均较对照组明显升高，存活组和死亡组与对照组比较均有统计学意义；TNF-α、IL-6、IL-10及APACHEⅢ评分四项指标两两之间呈显著性相关（P〈0．05）。结论促炎因子TNF-α、IL-6和抗炎因子IL-10在危重症患者中起重要作用，决定患者的预后。TNF-α、IL-6和IL-10浓度同APACHEⅢ评分一样可作为危重症预警的价值参数。
Heavy vehicle roughness band index: an alternative trigger for pavement rehabilitation

Field: Engineering (Physical Sciences)

This report has developed a new index, the Heavy Vehicle Roughness Band Index (HVRBI), as a measure of ride quality for heavy vehicles. The HVRBI is intended for use by road asset managers as a trigger to initiate pavement intervention works targeted at maintaining ride quality, freight productivity, safety and driver comfort for heavy vehicles. This built on the previous research and addressed the four elements of heavy vehicle ride quality being: vehicle speed, wheelbase length, the amplitude of the road profile and the lateral vibrations that result from differences in the wheel paths. These elements were combined to produce a modified variance as an indicator of ride quality based on a half-truck model incorporating the full mechanical response of heavy vehicles affecting driver comfort.
BACTERIAL ENDOCARDITIS TWO DECADES AFTER PENICILLIN

Field: Medicine (Health Sciences)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Optimally Suppressed\nPhonon Tunneling in van der Waals\nGraphene–WS<sub>2</sub> Heterostructure with Ultralow Thermal\nConductivity

Field: Materials Science (Physical Sciences)

Van der Waals heterostructures have great potential for\nrealizing\nultimately low thermal conductivity because defectless interfaces\ncan be constructed at a length scale smaller than the phonon wavelength,\nallowing modulation of coherent phonon transport. In this Letter,\nwe demonstrate the mechanism for thermal conductivity reduction at\na mode-resolved level. The graphene–WS<sub>2</sub> heterostructure\nwith the lowest cross-plane thermal conductivity of 0.048 W/(m·K)\nis identified from 16,384 candidates by combining Bayesian optimization\nand molecular dynamics simulations. Then, the angle-resolved phonon\ntransmission is calculated using the mode-resolved atomistic Green’s\nfunction. The results reveal that the optimal heterostructure nearly\ncompletely terminates phonon transport with finite incident angles,\nowing to the reduced critical incident angle and suppression of phonon\ntunneling.