jimnoneill/paper-to-field-training huggingface dataset:
The EU Arctic policy and its critique: a view under Tocci´s theory on foreign policy and normative power (Part 1)

Field: Social Sciences (Social Sciences)

What is the role of the European Union (EU) in the Arctic region? On what basis does it claim influence and/or authority (if any) over part of this vast area of the world? What can we learn about EU Arctic policy, tools and instruments adopted so far? Is the EU a normative foreign policy actor as described by Tocci´s theory? What factors do influence the adoption and validity of EU policies in this region? This study tries to reply to all these questions casting a light over an area of great geostrategic importance and at the crossroads of historic developments. In a first part we study the current EU Arctic policy and assess its strength and weaknesses according to literature. In a second part we summarize Tocci´s theory on kinds of normative policy actors and examine what kind of power is the EU exercising in the region.
Real‐Time Optimization Using Machine Learning Models Applied to the 4,4′‐Diphenylmethane Diisocyanate Production Process

Field: Chemical Engineering (Physical Sciences)

Abstract In this work, the optimal time‐varying allocation of steam in a large‐scale industrial isocyanate production process is addressed. This is a problem that falls into the category of real‐time optimization (RTO). The application of RTO in practice faces two problems: First the available rigorous process models may not be suitable for use in real‐time connected to the process. Second, there is always a mismatch between the predictions of the model and the behavior of the real plant. We address the first problem by training a neural net model as a surrogate to data generated by a rigorous simulation model so that the model is simple to implement and short execution times result. The second problem is tackled by adapting the optimization problem based on measured data such that convergence to the optimal operating conditions for the real plant is achieved.
PROGRESSION OF TGF-β/SMAD SIGNALING PATHWAY AND TGF-β_1 AND SMAD4 IN CERVICAL CARCINOMA

Field: Medicine (Health Sciences)

The transforming growth factor-β(TGF-β)/smad signaling pathway has an important role in carcinogenesis.In recent years,many investigations have revealed that TGF-β super-family ligands,receptors,smads protein,up stream and down stream regulators and cross-talk among many signaling pathways function in the correlative cancer.This review attempts to state transforming growth factor-β/smad signaling pathway and factor-β1、smad4 in cervical carcinoma.
Study on the impact of atmosphere to land surface brightness temperature by applying IR data of geostationary satellite

Field: Earth and Planetary Sciences (Physical Sciences)

The atmospheric weaken revised formula is obtained by simplifying split window algorithm. Land surface brightness temperature of the six monitoring regions of China is researched by using FY 2C geostationary satellite IR data (211 images from September 18, 2007 to August 15, 1008) with the above formula, the result shows that the impact of atmosphere to thermal infrared transmission is from −12K to 8 K. This paper inversed land surface brightness temperature with the FY geostationary satellite image at 4:02 am, October 4, 2007 excluding the impact of atmosphere, the image was more distinct after inversion than that before inversion.
SU-GG-T-235: Consistency and Reproducibility of the VMAT Plan Delivery Using Three Independent Validation Methods

Field: Health Professions (Health Sciences)

Purpose: The aim of he study is to evaluate the consistency and reproducibility of a prostate and a lung VMAT plans case for 31 consecutive days using three different approaches. Materials and methods: For each plan, a pre-treatment delivery was performed and the measurements obtained (dynalog files, planar dose with seven29, and the fluence from DAVID) were used as reference measurements. The remaining thirty (n=30) consecutive daily measurements were compared against the reference. The analysis of these DynaLog files have been carried out by in-house programming in MATLAB, by converting these ASCII files in to a 552 × 552 matrix that can be visualized as a gray level fluence image of the corresponding QA plan. In this work, we used the DAVID system, which is able to perform such quality assurance measurement while the patient is treated. The evaluation software compares the dose measured during radiotherapy to a reference dose, which was taken for each leaf pair during a reference measurement. In the third method, OCTAVIUS phantom with the Seven29 ion chamber array were used for comparing fluence verification. Results: The Dynalog files analysis showed that the variations between the reference fluence and the daily fluence were very low and the mean gamma index was as low as 0.01+/− 0.08. In our 30 days period of measurements using DAVID, the maximum variations were within 3% for both plans. Similar results observed in the analysis of the delivered dose as recorded by the seven29 ionization chamber array. Conclusions: All methods showed minimal daily deviations that contributed to clinically insignificant dose variations from day to day. Based on our results, we conclude that the VMAT delivery using a Varian 2100CD linear accelerator equipped with 120MLC is highly reproducible. “Research sponsored by PTW-Freiburg Company.”
The breakdown of trust in decision making about GM crops in a knowledge deficit

Field: Social Sciences (Social Sciences)

In a society that is becoming increasingly sceptical of scientific innovation, any novel technological advance which has the potential to dramatically alter some aspect of society will face criticism. Biotechnology is no exception. Trust is crucial for its acceptance, as society lacks both broad scientific understanding and specific. biotechnological knowledge. In recent years, society’s trust in science and scientific regulation has been severely dented. Questions of scientific independence and credibility, the negative impacts of previous innovations, and the contrasting views of experts and society, have all played their part in the diminution of society’s trust of scientific innovation, and the capacity of those charged with regulating these innovations. When it comes to regaining trust, one-way dialogue ‘informing’ society of the regulatory steps taken to ensure safety has been shown not to work. We suggest a more inclusive approach, which incorporates societal concerns within the regulatory assessment in a transparent an explicit way, is needed to rebuild societal trust. While the regulatory process only includes the concerns of scientific experts, there will always be criticisms of its scope and the impartiality of experts and the validity of the underlying science.
Use of oxygenator with short‐term ventricular assist devices

Field: Medicine (Health Sciences)

Abstract Venoarterial extracorporeal membrane oxygenation (VA‐ECMO) serves as a conventional short‐term mechanical circulatory assist to support heart and lung functions. The short‐term ventricular assist devices (ST‐VAD) can, on the contrary, offer only circulatory support. A combination of VAD and oxygenator (Oxy‐VAD) could help overcome this potential disadvantage. This is a retrospective case note study of patients supported on ST‐VAD which required adding an oxygenator for extra respiratory support. The oxygenator was introduced in the ST‐VAD circuit, either on the left or the right side. Twenty‐two patients with the etiology of refractory cardiogenic shock in decompensation were supported on Oxy‐VAD between years 2009 and 2019 at tertiary care . All patients were classified into class‐I INTERMACS with a mean SOFA Score of 14 ± 2.58. 86.4% of patients were already on mechanical support pre‐ST‐VAD implant, 80% on VA‐ECMO. The BiVAD implant accounted for 63.6%, followed by LVAD and RVAD with 27.3% and 9.1%. Mean duration of the ST‐VAD was 8.5 days. The oxygenator was introduced in 14 RVAD and 8 LVAD circuits. The oxygenator was successfully weaned in 54.5% while ST‐VAD was explanted in 31.8%. Discharge to home survival was 22.7%. Oxy‐VAD proves a viable, and probably, a better option to VA‐ECMO in acute cardiorespiratory decompensation. It offers organ‐specific tailor‐made support to the right and/or left heart and/or lungs. While on Oxy‐VAD support, each organ performance can be assessed independently, and the assistance of the specifically improved organ can be weaned off without discontinuing the support for the rest.
THE EFFECT OF THE COMBINED ACTION OF AN ALTERNATING MAGNETIC FIELD AND LOW-FREQUENCY VIBRATION ON THE EARLY STAGES OF ONTOGENESIS AND MORPHOMETRY OF ZEA MAYS L.

Field: Agricultural and Biological Sciences (Life Sciences)

The work identifies environmentally safe parameters of physical factors under which stimulating plant responses were observed. For samples 6 and 10, an alternating magnetic field neutralized the inhibitory effect of vibration with a frequency of 8 and 13 Hz. For samples 8, 14 and 16, the alternating magnetic field enhanced the stimulating effect of vibration. Under the influence of an alternating magnetic field and 55 Hz vibration, the combined effect of factors reduces growth rates. The most valuable, from the point of view of environmental safety, are the identified parameters of physical factors that lead to the death of a part of the sample, a significant inhibition of the growth processes of surviving organisms, as well as a decrease in biological productivity. When evaluating the data obtained, vibrations with a frequency of 5 Hz, 8 Hz, 13 Hz, as well as the combined effect of an alternating magnetic field and vibrations of 5 and 16 Hz, turned out to be critical for plants. Keywords: environmental safety; Zea mays L.; alternating magnetic field; magnetic induction; ontogenesis; morphometry.
Electrophysiology of hiPSC-Cardiomyocytes Co-Cultured with HEK Cells Expressing the Inward Rectifier Channel

Field: Neuroscience (Life Sciences)

The immature electrophysiology of human-induced pluripotent stem cell-derived cardiomyocytes (hiCMs) complicates their use for therapeutic and pharmacological purposes. An insufficient inward rectifying current (IK1) and the presence of a funny current (if) cause spontaneous electrical activity. This study tests the hypothesis that the co-culturing of hiCMs with a human embryonic kidney (HEK) cell-line expressing the Kir2.1 channel (HEK-IK1) can generate an electrical syncytium with an adult-like cardiac electrophysiology. The mechanical activity of co-cultures using different HEK-IK1:hiCM ratios was compared with co-cultures using wildtype (HEK–WT:hiCM) or hiCM alone on days 3–8 after plating. Only ratios of 1:3 and 1:1 showed a significant reduction in spontaneous rate at days 4 and 6, suggesting that IK1 was influencing the electrophysiology. Detailed analysis at day 4 revealed an increased incidence of quiescent wells or sub-areas. Electrical activity showed a decreased action potential duration (APD) at 20% and 50%, but not at 90%, alongside a reduced amplitude of the aggregate AP signal. A computational model of the 1:1 co-culture replicates the electrophysiological effects of HEK–WT. The addition of the IK1 conductance reduced the spontaneous rate and APD20, 50 and 90, and minor variation in the intercellular conductance caused quiescence. In conclusion, a 1:1 co-culture HEK-IK1:hiCM caused changes in electrophysiology and spontaneous activity consistent with the integration of IK1 into the electrical syncytium. However, the additional electrical effects of the HEK cell at 1:1 increased the possibility of electrical quiescence before sufficient IK1 was integrated into the syncytium.
Gastric Carcinoma and Acute Perforation

Field: Medicine (Health Sciences)

DiscussionTo us the most interesting features of this case are the neurological findings and the effect of cortisone.The neurological findings noted at the first examination are well expressed by the term " mononeuritis multiplex," which was introduced by Lovshin and Kernohan (1949), who recorded such findings in eight cases.These mani- festations, when present, are very suggestive of poly- arteritis nodosa, particularly if there be pyrexia and signs suggesting dysfunction of other organs or systems.The findings at the second examination were those of an advanced polyneuritis, and indicate the necessity of con- sidering polyarteritis nodosa in all cases of peripheral neuritis.Histological examination of the necropsy material demonstrates the absence of an inflammatory infiltration around the areas of fibrinoid necrosis in the smaller arteries.When considered in relation to the intense perivascular inflammatory infiltration -present in the biopsy specimen obtained 32 days before death it seems justifiable to regard the, change as due to corti- sone.This is in accordance with the findings of Shick, Baggenstoss, and Polley (1950), who treated three cases with cortisone.Two patients died in cardiac and renal failure in spite of initial improvement.Necropsy showed complete healing of all arterial lesions, but with the process of healing fibrous obliteration of the lumen of the vessels had occurred with widespread visceral infarction.It is therefore evident that cortisone can be a twoedged weapon.If it eventually proves to be of value in the treatment of polyarteritis nodosa it will be of great importance to begin treatment at such an early stage that healing of affected vessels will not provoke serious visceral infarction.In consequence the early diagnosis of polyarteritis nodosa is desirable so that the effect of cortisone given at the onset of the disease can be inves- tigated.As can be seen from the present and other recorded cases, this, in spite of a high index of suspicion, may be extremely difficult.
Effect of provider and patient reminders, deployment of nurse practitioners, and financial incentives on cervical and breast cancer screening rates

Field: Health Professions (Health Sciences)

<p>Objective : To evaluate the effect of the Provider and Patient Reminders in Ontario: Multi-Strategy Prevention Tools (P-PROMPT) reminder and recall system and pay-for-performance incentives on the delivery rates of cervical and breast cancer screening in primary care practices in Ontario, with or without deployment of nurse practitioners (NPs). </p> <p>Design : Before-and-after comparisons of the time-appropriate delivery rates of cervical and breast cancer screening using the automated and NP–augmented strategies of the P-PROMPT reminder and recall system. </p> <p>Setting : Southwestern Ontario. </p> <p>Participants : A total of 232 physicians from 24 primary care network or family health network groups across 110 different sites eligible for pay-for-performance incentives. </p> <p>Interventions : The P-PROMPT project combined pay-for-performance incentives with provider and patient reminders and deployment of NPs to enhance the delivery of preventive care services. </p> <p>Main outcome measures : The mean delivery rates at the practice level of time-appropriate mammograms and Papanicolaou tests completed within the previous 30 months. </p> <p>Results : Before-and-after comparisons of time-appropriate delivery rates (<30 months) of cancer screening showed the rates of Pap tests and mammograms for eligible women significantly increased over a 1-year period by 6.3% (P >< .001) and 5.3% (P < .001), respectively. The NP-augmented strategy achieved comparable rate increases to the automated strategy alone in the delivery rates of both services. </p> <p>Conclusion : The use of provider and patient reminders and pay-forperformance incentives resulted in increases in the uptake of Pap tests and mammograms among eligible primary care patients over a 1-year period in family practices in Ontario.</p>
Automated Laboratory Stand for Determining the Cogging Torque of a Small Permanent Magnet Electric Machine Using the MATLAB Environment

Field: Engineering (Physical Sciences)

The phenomenon of the occurrence of cogging torque is one of the basic disadvantages of permanent magnet motors. An important aspect of designing a machine with magnetoelectric excitation is the formation of the magnetic circuit in such a way as to reduce this negative phenomenon. Due to the tolerances of the production of motor components, an important part of the design work is research into the properties of the designed machines on the built prototypes. This paper presents concepts and implementations for the construction of an automated laboratory station to determine the course of cogging torque. The measurement method, the concept, and implementations of the construction of the laboratory station are presented in this paper. The paper is summarized by a discussion of the results of laboratory tests on selected permanent magnet motors.
Role relations in the family: characterization of beliefs of boys and girls in the period of matrimonial choice

Field: Psychology (Social Sciences)

Introduction. The family as a resource for psychological well-being influences the formation of personal beliefs about interpersonal and role-based family relationships. The reflected experience of relationships in the family of origin and subjective models of interaction with the world are reflected in the beliefs of boys and girls about the family structure. Beliefs about role relationships in the family influence the matrimonial behaviour of the individual, determining the choice of a strategy of actions based on the hierarchy of family values. Purpose. Identification and description of the features of the content of the individual’s beliefs about role relationships in the family during the period of matrimonial choice. Materials and methods. The study involved 135 people (55 boys and 80 girls, aged 17-21 years), students from Adygea State Pedagogical University, who are in the matrimonial choice period. The Role Expectations and Claims in Marriage (RESM) test by A. N. Volkova and the Distribution of Roles in the Family methodology by Yu. E. Alyoshina, L. Ya. Gozman, E. M. Dubovskaya were applied. A comparative analysis of the severity of beliefs about the desired role behaviour of the future marriage partner in boys and girls was carried out. Results. The specificity and gender differences in the severity of beliefs indicators about the distribution of roles in the family among modern students are shown, taking into account the gender factor. The importance of personal identification with a partner is reflected (girls have an average score of 6.9, boys 5.6 according to the RECM method) and the expected performance of the emotional-psychotherapeutic function by the family (average score 7.2 for girls and 6.6 for boys). The beliefs of students of both sexes about the structure of the family reflect the features of the egalitarian type of family, that is, the expectations of equal partnership in the family (the results obtained using the Distribution of Roles in the Family methodology showed no significant differences in the views of girls and boys). Discussion and conclusion. The adequacy of the reality of ideas about the requirements for a partner, the subject of role behaviour, provides awareness of matrimonial choice, which is necessary for building a prosperous and constructive interaction in the family. In conclusion, the effectiveness of art therapy in psychological support programmes for the development of constructive ideas about the psychological determinants of a successful family among young people is emphasized.
siRNA-Mediated Silencing of 5-Lipoxygenase Gene (ALOX5) Reduces Necrosis of Cardiomyocytes at Anoxia- Reoxygenation

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

In experiments on the primary culture of isolated neonatal rat cardiomyocytes it was determined that cardiomyocytes express ALOX5 gene encoding enzyme 5-lipoxygenase. Anoxia-reoxygenation does not affect significantly expression of 5-lipoxygenase mRNA in cardiomyocytes. Transfection into cardiomyocytes 5-lipoxygenase-specific small interfering RNA's (siRNA) lead to significant reducing of 5-lipoxygenase mRNA expression in cardiomyocytes after 24 hours of cultivation. ALOX5 gene silencing resulted in improved cell survival during anoxia-reoxygenation. Obtained results indicate that siRNA against ALOX5 effectively protects cardiomyocytes against A/R injury.
Brain Stem Auditory Evoked Responses in Clinical Practice

Field: Neuroscience (Life Sciences)

A relatively new noninvasive technique for the diagnosis of abnormalities affecting the central nervous system is presented. It is especially useful in patients with acoustic neuroma, brain stem disorder such as tumors of the posterior fossa with neuraxis impingement, as well as demyelinating disorders such as multiple sclerosis. It is certainly useful in the verification of neurologic normalcy in patients complaining of dizziness and vertigo.
Increasing The Fine Particle Content In Metal Powders For LPBF Through Nanoparticle Dry-coating

Field: Materials Science (Physical Sciences)

In powder-bed-based additive manufacturing (AM) processes, such as laser powder bed fusion (LPBF) typically the fine particles (less than 20 µm) are removed from metal powders in order to decrease powder cohesion that often results in inhomogeneous powder spreading. Nanoparticle dry-coating effectively reduces particle adhesion and allows for direct usage of the fine particles. A gas-atomized Cr25Co25Ni25Fe25 powder (less than 90 µm) with varying fine content was dry-coated with SiO2 nanoparticles (13 nm) in increasing concentrations up to 50 ppm. Measurements of flowability (dynamic angle of repose) and powder packing (Hausner-ratio) indicated a better processability of dry-coated powders upon nanoparticle addition. Nanoparticle dry-coated metal powders with a fine particle content of 20 vol.% showed a homogenous processing in a LPBF machine and a high relative part density >99.9%. The utilized fine fraction increased the powder yield, clearly highlighting the potential of dry-coating for AM technologies.
School of Nursing, Itigidi REGISTRATION FORM/APPLICATION FORM IS OUT CALL 09078816209!!! The school Admin hereby informs all interested applicants to call 09078816209 in order to participate in the online application exercise for 2022/2023 Academic session. Follow the simple steps below to apply for obtaining the School of Nursing application form

Field: Nursing (Health Sciences)

&nbsp;School of Nursing, Itigidi &nbsp;REGISTRATION FORM/APPLICATION FORM IS OUT CALL 09078816209!!! The school Admin hereby informs all interested applicants to call 09078816209 &nbsp;in order to participate in the online application exercise for 2022/2023 Academic session. Follow the simple steps below to apply for obtaining the School of Nursing application form
Analysis of Design For Assembly (Dfa) in Exhaust Product Design

Field: Engineering (Physical Sciences)

GRIP Exhaust is a small and medium industry which is engaged in manufacturing which produces mufflers. The production system in this company is to apply a production system made to order, where consumers can order exhaust products according to their requests. Designing exhausts according to technical specifications by applying the Design For Assembly (DFA) method and calculating the time required to assemble custom exhaust products into technical specifications by producing products according to user needs. With Design For Assembly (DFA) to make it easier and push time, but still focus on the function of the product itself and pay attention to the safety factor of its performance. custom stainless steel exhaust takes 2 hours to complete, rust-resistant quality, an efficiency value of 1.23, and has higher advantages and attractiveness in the eyes of consumers.