jimnoneill/paper-to-field-training huggingface dataset:
Malaysian general music teachers’ attitudes and practices inmulticultural music education

Field: Arts and Humanities (Social Sciences)

The awareness of the importance of multicultural music in the Malaysian primary music education has increased due to the requirements set by the National Curriculum Standards for Primary School in music education in Malaysia. Therefore, it can be said that multicultural music is not an optional component to be included or disregarded at the discretion of the teacher in the music classroom. Music teachers are expected to foster multicultural music educational programs that address the diverse needs of students. in the context of sustainability of multicultural music education, it is important to know that the current status of music teachers’ attitudes and practices with regard to multicultural music education such as what and how effective are the practices and their perceptions as far as the multicultural music is concerned. Therefore, this study examined Malaysian general music teachers’ utilization of multicultural music education in the music curriculum, specifically exploring the relationship between the general music teachers’ attitudes and their efforts in developing and implementing multicultural music education in music classes. This study utilized an adaptation of the original Music Specialist’s Multicultural Music Education Survey instrument which was administered to 456 of primary schools’ general music teachers in Malaysia. This instrument was used to measure teachers’ attitudes and practices regarding multicultural music education. Data analysis included descriptive statistics, analysis of variance (ANOVA) and correlational analysis (pearson product-moment correlation). Results indicate that there is limited implementation of multicultural music education in the music classrooms due to inadequate preparation and limited resources, and insufficient knowledge in multicultural music. As such, it is important to ensure music teachers develop a more critical understanding of multicultural music education include producing and developing more instructional materials and learning aids, which are suitable for primary students and appropriate for the Malaysian context. Hence, music teacher training programs are needed in order to address both theoretical and practical aspects of multicultural music education throughout the curriculum in a comprehensive and long-term manner.
Review on importance of energy efficiency in hospitality

Field: Business, Management and Accounting (Social Sciences)

Taking into consideration that lately tourism has become one of the most significant economic activities, and hospitality as its main key part there is a need to observe constant market trend changes in order to achieve business improvements for hoteliers. Modern technologies in hospitality influence on cost reduction, increase of profit and competitiveness, and finally on enhancing guests' satisfaction. The usage of modern technologies in rational use of energy is of strategic importance for every hotel company due to reduction of costs, strengthens of competitiveness, increases of productivity, and on the other side, becomes a strategic tool which influences on business efficiency improvement. Therefore, there is a natural need and feeling of those who are stakeholders of tourism and hospitality to inform themselves about new technologies. The aim of this article is to provide insight into the latest trends, necessities and current issues in the field of for rational use of energy in all areas of hotel operations, which will result in the creation of high-quality services and provide full customer satisfaction.
Hyaluronic acid in the treatment of dry eye disease

Field: Medicine (Health Sciences)

Abstract Dry eye disease (DED) is a highly prevalent and debilitating condition affecting several hundred million people worldwide. Hyaluronic acid (HA) is a naturally occurring glycosaminoglycan commonly used in the treatment of DED. This review aims to critically evaluate the literature on the safety and efficacy of artificial tears containing HA used in DED treatment. Literature searches were conducted in PubMed, including MEDLINE, and in Embase via Ovid with the search term: “(hyaluronic acid OR hyaluronan OR hyaluronate) AND (dry eye OR sicca)”. A total of 53 clinical trials are included in this review, including eight placebo‐controlled trials. Hyaluronic acid concentrations ranged from 0.1% to 0.4%. Studies lasted up to 3 months. A broad spectrum of DED types and severities was represented in the reviewed literature. No major complications or adverse events were reported. Artificial tears containing 0.1% to 0.4% HA were effective at improving both signs and symptoms of DED. Two major gaps in the literature have been identified: 1. no study investigated the ideal drop frequency for HA‐containing eyedrops, and 2. insufficient evidence was presented to recommend any specific HA formulation over another. Future investigations assessing the optimal drop frequency for different concentrations and molecular weights of HA, different drop formulations, including tonicity, and accounting for DED severity and aetiology are essential for an evidence‐based, individualized approach to DED treatment.
ATF6 Activation Remodels the Endoplasmic Reticulum Proteostasis Network to Restore Proteostasis of Pathogenic GABA A Receptors

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The protein homeostasis (proteostasis) network in the endoplasmic reticulum (ER) regulates the folding, degradation, and trafficking of membrane proteins. Deficiency in protein folding of g-aminobutyric acid type A (GABAA) receptors, the primary inhibitory ion channels in mammalian central nervous systems, reduces their functional expression on the plasma membrane, thus causing various neurological diseases, such as idiopathic epilepsy. For example, The A322D mutation in the a1 subunit causes its misfolding and thus excessive ER-associated degradation, leading to autosomal dominant juvenile myoclonic epilepsy. To restore the forward trafficking of misfolding-prone GABAA receptors, it is essential to correct their misfolding behavior per se in the ER. The unfolded protein response (UPR) remodels the ER proteostasis network to handle misfolded proteins, and the ATF6 branch is considered as the critical transcription factor in the UPR that enhances the ER folding capacity by influencing ER chaperones and folding enzymes. Here, we showed that expressing a1(A322D) subunits does not significantly induce the UPR. Modest activation of the ATF6 pathway promotes the folding and forward trafficking of the a1(A322D) to the plasma membrane in HEK293T cells expressing a1(A322D)b2g2 receptors. This effect partially results from the increased recruitment of BiP, a master regulator of the UPR, to the mutant receptors. Furthermore, application of BIX, a specific BiP activator through ATF6-dependnt pathway, substantially enhances the folding, trafficking, and function of the mutant receptors in HEK293T and neuronal SH-SY5Y cells. Our results demonstrated that activating the ATF6 pathway represents a promising strategy to restore proteostasis of loss-of-function protein conformational diseases. (A) A schematic cartoon figure of the pentameric GABAA receptors with two a1 subunits, two b2 subunits, and one g2 subunit. This homology model was built using the crystal structure of b3 subunits (4COF) as the template. (B) The a1 subunit has a large N-terminal domain, which is located in the ER lumen or extracellular space, and four transmembrane (TM) helices. Ala322 in the third TM helix is displayed as a space-filling model, indicated by an arrow. (A) A schematic cartoon figure of the pentameric GABAA receptors with two a1 subunits, two b2 subunits, and one g2 subunit. This homology model was built using the crystal structure of b3 subunits (4COF) as the template. (B) The a1 subunit has a large N-terminal domain, which is located in the ER lumen or extracellular space, and four transmembrane (TM) helices. Ala322 in the third TM helix is displayed as a space-filling model, indicated by an arrow.
The classroom and the polis : political action, dialogue and the project of pedagogy

Field: Arts and Humanities (Social Sciences)

This study explores students’ experiences in a dialogue-based program and what these experiences reveal about the possibility of creating dialogic classroom spaces that engage the political and support the emergence of students as political actors. The case study was a semester-long, undergraduate program in a comprehensive university in western Canada. The theme for dialogue was “Indigeneity in Canada: Past, Present, and Future.” In a qualitative case study, I observed classroom interactions, wrote field notes and interviewed students and instructors over the course of thirteen weeks. Working hermeneutically, I interpreted the data by placing it in conversation with the political theory of Hannah Arendt. The students’ experiences revealed the dialogue-based classroom as a pseudo-public space repeatedly under threat from the larger social pressures of conformity, utilitarian thinking and emotional self-interest. The students’ experiences in the program tell a story marked by profound struggles for political voice, authentic relations, and a sense of equality. Confounding students struggle to appear in the dialogue was the potentially volatile psychological dimension of learning. The inherent unpredictability of the classroom as a public space cast the teacher, not as ring-leader or director, but as one who attempted to hold open the spaces so that the students could continually return, willing to take the risk that speech and action are in the public realm.
Licensure requirements for interjurisdictional forensic evaluations.

Field: Psychology (Social Sciences)

In our increasingly mobile society, psychologists may be presented with greater opportunities to practice in jurisdictions outside of their licensure. Interjurisdictional practice has been particularly common under circumstances of litigation involving the services of psychological experts. Psychologists practicing elsewhere must abide by local licensing laws, which are not readily accessible., We sought clarification by surveying regulatory boards of the United States, Canada, and U.S. territories. Most jurisdictions allow interjurisdictional practice but with a variety of restrictions. A sizable minority of jurisdictions forbids such practice entirely. Disciplinary action for noncompliance may range from injunction to incarceration. Mobility programs and preventive measures can minimize risk.
Extraction of various metal ions by open-chain crown ether bridged diphosphates in supercritical carbon dioxide

Field: Chemistry (Physical Sciences)

Abstract Various toxic metal ions were successfully removed from solid matrix into supercritical CO 2 (scCO 2 ) by open-chain crown ether bridged diphosphates at 313.15 K and 20 MPa, these diphosphates with different ester side chains and different length of ethylene oxide bridge group are highly soluble in supercritical CO 2 . The extraction efficiency ( E %) of heavy metals is between 55 and 89%. Mulliken charge distribution of ligand’s P=O coordination group was calculated to indicate the stability of metal complex. The ligand structure effects and the rationale for different selectivity were discussed. In addition, binding property of these diphosphates towards the alkaline earth metals was further studied following the same extraction procedures. Alkaline earth metal ions Ca 2+ , Sr 2+ and Ba 2+ were extracted with E % at 49–74%, 50–73% and 16–64%, respectively. DFT calculations were performed to investigate the interaction energy of the complexes and the correlation with the E % was discussed.
Ketoconazole Treatment of Chronic Mucocutaneous Candidiasis

Field: Medicine (Health Sciences)

Five patients received ketoconazole treatment of chronic mucocutaneous candidiasis. One also had disseminated histoplasmosis and cryptococcosis. Ketoconazole was well absorbed after an oral dose of 200 mg and produced detectable antifungal blood levels for more than eight hours after each dose. Thrush cleared in less than two weeks in all patients. Cutaneous lesions cleared slowly during several months of treatment. A patient with polymycotic infection had a rapid clearing of candidiasis, but her histoplasmosis did not respond to three weeks of treatment. Adverse drug effects were minimal. Ketoconazole is a promising new agent for treatment of chronic mucocutaneous candidiasis.
Exploring the Nexus Between Culture, Values, Institutions, Happiness and Philanthropy: A Global Evidence

Field: Social Sciences (Social Sciences)

The main aim of this study was to investigate the impact of culture, values, institutions, and happiness on the world’s philanthropy. Culture is measured by Hofstede index (i.e. individualism-collectivism, masculinity-femininity, long and short-run orientation, uncertainty avoidance, power distance, and indulgence-restraint). The measurement of value is WVS (World Value Survey) and it consists of the emotion of happiness, active/ inactive membership of a church or religious organization, important in life; religion, confidence on charitable/ humanitarian organization and active/ inactive membership of charitable/ humanitarian organization. Institutions are measured by WGI (World Governance Indicators) and it consists of corruption, regulatory quality, accountability and voice, rule of law, political stability and government effectiveness, the sub-variables of happiness (index) are social support, freedom to take decisions and generosity and world’s philanthropy is measured by CAF (Charitable Aid Foundation) world giving index. We have gathered panel data (from the period 2010 to 2014) of CAF index, happiness index and WGI of 62 countries and cross-sectional data of CAF index, Hofstede index, WGI, happiness index and WVS of 24 countries. The result (of panel data) shows that there is a significant relation of WGI, social support and freedom of choice with CAF index whereas there is an insignificant connection between generosity and CAF index. The findings (of cross-sectional data of all factors combined) shows that there is a relation of the Hofstede index and happiness index with the CAF index while there is no linkage of WGI and WVS with the CAF index. The study suggests that charitable organizations should personify their value in order to build trust among the public. Countries should improve their governance because this will lead to equality and by doing this countries will also manage their resources efficiently and effectively.
Retzius‐sparing robot‐assisted radical prostatectomy using the Revo‐i robotic surgical system: surgical technique and results of the first human trial

Field: Medicine (Health Sciences)

Objective To evaluate the safety and proficiency of the Revo‐i ® robotic platform (Meere Company Inc.) in the treatment of prostate cancer ( PC a). Patients and Methods A prospective study was carried out on 17 patients with clinically localized PC a treated between 17 August 2016 and 23 February 2017 at our urology department using the Revo‐i. Patients underwent Retzius‐sparing robot‐assisted radical prostatectomy ( RS ‐ RARP ). The primary objective was to describe the RS ‐ RARP step‐by‐step surgical technique using the Revo‐i. In addition, the safety of the Revo‐i was assessed according to intra‐operative and the postoperative complications within 30 days of surgery. Early oncological outcomes were also assessed according to surgical margin status and biochemical recurrence ( BCR ). Continence was defined as use of no or only one pad. Surgeons’ satisfaction with the Revo‐i was assessed using the Likert scale. Results All surgeries were completed successfully, with no conversion to open or laparoscopic surgery. The median patient age was 72 years. The median docking time, console time, urethrovesical anastomosis time and estimated blood loss were 8 min, 92 min, 26 min and 200 mL, respectively. One patient was transfused intra‐operatively as a result of blood loss of 1 500 mL . Postoperatively, two patients received blood transfusion, and there were no other serious/major complications. The median hospital stay was 4 days. At 3 months, four patients had positive surgical margins, one patient had BCR , and 15 patients were continent. Most of surgeons were satisfied with the Revo‐i performance. Conclusions The first human study for the treatment of patients with localized PC a using the Revo‐i robotic surgical system was carried out successfully. The peri‐operative, early oncological and continence outcomes are encouraging. Further prospective studies are warranted to support our preliminary results.
Fiber - Optic Loop Network With Active Nodes For An Electrical Power Plant

Field: Engineering (Physical Sciences)

This paper presents a fiber optic loop network for a measurement and control system of an electric power plant. The network consists of the central computer terminal, the set of specially distributed digital FO links and local station installed at the important power facilities. The well-known FO link advantages contribUte to high reliability and safety of work of the system. The operation of the loop network, treated as an autonomous one, is controlled by a microcomputer system. Transmission protocols and the cooperation with the local station are also described. The proposed loop network model is illustrated with an example of the laboratory - scale system.
ITCHING ERUPTION IN MINERS CAUSED BY A RARE BEETLE (TRIBOLEUM CASTANEUM).

Field: Medicine (Health Sciences)

Journal Article ITCHING ERUPTION IN MINERS CAUSED BY A RARE BEETLE (TRIBOLEUM CASTANEUM). Get access D. M. WILLIAMSON, M.D., D.I.H. D. M. WILLIAMSON, M.D., D.I.H. Medical Services, National Coal Board, Yorkshire Division, Doncaster Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 76, Issue 8-9, 1 August 1964, Pages 388–389, https://doi.org/10.1111/j.1365-2133.1964.tb14549.x Published: 01 August 1964
An efficient method of generating skin fibroblast cells for cell banking

Field: Veterinary (Health Sciences)

An optimum cell culture medium is used to generate fibroblast cells for cell banking. Here, we describe a method for obtaining higher number of pure fibroblast cells in much shorter duration from skin tissue explants. Two pronged strategy was used, first two different culture media were selected, one for preferential generation of fibroblast cells in primary culture (Human fibroblast specific media- HifibroXL) and another for their faster multiplication in secondary culture (DMEM + Ham's F12). Secondly, tissue explants were cultured not only once but up to six times increasing the generation of primary cells per se. This method initially standardized with buffalo (Bubalus bubalis) skin tissue explants works efficiently with camel (Camelus bactrianus) and horse (Equs caballus). Modified cell culture method increases the efficiency of establishing fibroblast cell banks by reducing the cost both in terms of consumables and human effort. It is well suited for today's fast-paced conservation laboratories.
CYTOKININS: SYNTHESIS, MASS SPECTRA, AND BIOLOGICAL ACTIVITY OF COMPOUNDS RELATED TO ZEATIN

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Compounds related to dihydrozeatin that define the influence of the location of the hydroxyl group along the side chain have been synthesized and tested for cytokinin activity. The compounds compared are in the series: 6-(X-hydroxy-3-methylbutylamino)purines and their ribosides, where X = 2, 3, and 4. Hydroxy substitution on the 4-position of the side chain enhances, but in the 2-, 3-, or 2- and 3- positions, decreases cytokinin activity as compared with the unsubstituted isopentyl (or isopentenyl) chains. This differential influence of the position of the hydroxyl group in the N 6 -chain holds also for the similarly related 9-β-D-ribofuranosides. The relatively higher activity of 3,4-dihydroxy as compared with 2,3-dihydroxy derivatives is consistent with this position effect. Compounds related to zeatin possessing side-chain ester moieties have also been synthesized and tested comparatively. Among these, 6-(4-acetoxy-3-methyl- trans -2-butenylamino)purine is at least as active as zeatin, the most active presently known cytokinin in the tobacco bioassay, whereas the analog, methyl 2-methyl-4-(purin-6-ylamino)- trans -crotonate, with the ester function effectively reversed, has vastly lower activity, and its riboside is practically inactive.
Studies on the locomotory behaviour and adhesive properties of mononuclear phagocytes from blood

Field: Medicine (Health Sciences)

S ummary Mononuclear phagocytes isolated from peripheral blood move slowly on albumin‐, collagen‐ and fibronectin‐coated glass, as judged by analysis of time‐lapse film, although their movement is stimulated somewhat by serum. When a differential‐adhesion method is used to purify monocytes from a crude mononuclear cell fraction it appears to select a particularly slow‐moving sub‐group. Despite their slow rate of movement (especially in comparison with neutrophils) monocytes move over and penetrate monolayers of endothelial cells, apparently without difficulty; they are, however, restricted to the upper surface of a fibroblast monolayer. Penetration of reconstituted collagen gels by freshly isolated monocytes was not observed but cultured monocytes, which spontaneously detached from the culture substratum over a 48 h period, did invade collagen gels. The adhesive properties of these cultured cells, measured in a flow‐chamber assay, did not differ from freshly isolated monocytes purified on serum‐coated dishes and detached with EDTA, and their invasive capacity does not seem to be a consequence of altered adhesive properties. The behavioural differences between monocytes and neutrophils are considerable, although both cell types have to leave the circulation and penetrate tissues in vivo .
Can the galling Eriophyidae (Trombidiformes) manipulate leaf structural and histochemical profiles over environmental stressors?

Field: Agricultural and Biological Sciences (Life Sciences)

Context Galls are products of an intrinsic relationship between specific parasites and their host plants. Gall formation involves alterations in the developmental pattern of the host organs in which environmental conditions may also impose constraints. Aims We hypothesised that the adaptive features of the host plants reflect the stressors of the xeric and mesic environments and influence the establishment and success of the associated galls. Methods We analysed anatomical, histometric, and histochemical alterations induced by two species of Eriophyidae, on Miconia ibaguensis adapted to the Brazilian Cerrado (xeric environment) and on Miconia notabilis adapted to the forests of the equatorial region (mesic environment). Key results The adaptive leaf characteristics of M. ibaguensis and M. notabilis to both xeric and mesic environments, such as the trichomes, cuticle and mesophyll thickness, number of mesophyll layers, the proportion of intercellular spaces, differences in the intensity detection of phenolic and starch are kept in the galls. The higher density of emergences in M. notabilis may increase the protection against the natural enemies of the eriophyids, which are commonly more abundant in mesic than in xeric environments. Conclusions These traits are important not only for the survival of the two host plants but also for the success of the two species of galling Eriophyidae in distinct environments. Implications These findings indicate the success of the gall inducers of the same taxa in distinct environments, which can be explored in different systems.