jimnoneill/paper-to-field-training huggingface dataset:
AZAS-AZAS KEBIJAKAN SISTEM PENYELENGGARAAN KETENAGAKERJAAN DI KABUPATEN PASURUAN

Field: Social Sciences (Social Sciences)

Government efforts in overcoming the global economic crisis are carried out jointly with the community, especially business people, one of the main reasons for stabilizing the economy and maintaining monetary balance and avoiding the bankruptcy of most companies that have an impact on the majority of workers and ends in termination of relations work. So the role of the actors in implementing local regulations is expected to be overcome, and can realize the capability that exists so that they can run local regulations and can improve their respective roles which ultimately can create a balance between the government, companies and workers who are disadvantaged but with the high school to get good welfare company workers and the government so that they can improve performance with a work ethic, then show human resources that can encourage economic growth and development and realize advanced regions, independent work competitiveness and no more problems for implementing actors Implementation of the Perda. This study was designed with a qualitative research method that uses a case study approach to determine the role of actors in implementing Regional Regulation No. 22 of 2012 concerning the Employment Management System (Study of Industrial Relations in Pasuruan Regency. The data analysis uses interactive model data analysis developed by Miles, Huberman and Saldana, while data collection was conducted through literature studies, field observations, and indept interviews, all data were simulated in depth, comprehensively, and corrected each other in a Focus Group Discussion (FGD).
<title>Degree of freedom, interconnect capacity, and connectivity</title>

Field: Physics and Astronomy (Physical Sciences)

In this paper, in order to properly promote usage's of optics for future interconnection applications, we revisit some fundamental physics governing light propagation in linear media. In particular, we wish to address how the point-topoint data communication capacity is related to the degree of freedom (DOF) of optics, and how packaging and other constraints limit the DOF of optics for exercising its power of interconnections. We hope that a correct understanding of the fundamentals of optics for interconnections can help maximize its advantages while bypassing its drawbacks.
Monocular Stereoscopic Perception of Disparate Images

Field: Psychology (Social Sciences)

20 Ss were presented stereograms alternately to one eye. In a range of alternation rates of 2.1 to 10.0 cps with a mean of 5.5 cps, 18 Ss reported perception of stereoscopy. Due to retinal interactions between the two views the scene was also seen as vibrating. This phenomenon is important both to the question of the relation between monocular movement parallax and binocular stereopsis and to the theory of a binocular cyclopean field (Hochberg, 1964).
SLE like Mouse Model Induced by Chronic Graft Versus Host Reaction

Field: Medicine (Health Sciences)

Purpose To establish a SLE like mouse model induced by chronic graft versus host reaction (GVHR). Methods Inoculation of (BALB/C×C 57 BL/6) F1 generation mice with lymphocytes from BALB/C parental strain individuals by intravenous injection.Levels of serum IgG autoantibody to dsDNA and total histones were determined by ELISA method.Antinuclear antibodies (ANA) and immune complex in glomeruli were observed by immunofluorescent stain,antibodies against extractable nuclear antigens were determined by immunoblot assay. Results Chronic GVHR can induce anti dsDNA antibodies and other ANA.Anti DNA antibody positive mice had marked immune complex deposits in glomeruli. Conclusions Chronic GVHR can induce a syndrome strongly resembling human SLE.
Faculty Opinions recommendation of Mast cells promote atherosclerosis by releasing proinflammatory cytokines.

Field: Medicine (Health Sciences)

Mast cells contribute importantly to allergic and innate immune responses by releasing various preformed and newly synthesized mediators. Previous studies have shown mast cell accumulation in human atherosclerotic lesions. This report establishes the direct participation of mast cells in atherogenesis in low-density lipoprotein receptor-deficient (Ldlr(-/-)) mice. Atheromata from compound mutant Ldlr(-/-) Kit(W-sh)(/W-sh) mice showed decreased lesion size, lipid deposition, T-cell and macrophage numbers, cell proliferation and apoptosis, but increased collagen content and fibrous cap development. In vivo, adoptive transfer of syngeneic wild-type or tumor necrosis factor (TNF)-alpha-deficient mast cells restored atherogenesis to Ldlr(-/-)Kit(W-sh/W-sh) mice. Notably, neither interleukin (IL)-6- nor interferon (IFN)-gamma-deficient mast cells did so, indicating that the inhibition of atherogenesis in Ldlr(-/-)Kit(W-sh/W-sh) mice resulted from the absence of mast cells and mast cell-derived IL-6 and IFN-gamma. Compared with wild-type or TNF-alpha-deficient mast cells, those lacking IL-6 or IFN-gamma did not induce expression of proatherogenic cysteine proteinase cathepsins from vascular cells in vitro or affect cathepsin and matrix metalloproteinase activities in atherosclerotic lesions, implying that mast cell-derived IL-6 and IFN-gamma promote atherogenesis by augmenting the expression of matrix-degrading proteases. These observations establish direct participation of mast cells and mast cell-derived IL-6 and IFN-gamma in mouse atherogenesis and provide new mechanistic insight into the pathogenesis of this common disease. PMID: 17546038 Funding information This work was supported by: NHLBI NIH HHS, United States Grant ID: HL67249 NHLBI NIH HHS, United States Grant ID: R01 HL075026 NHLBI NIH HHS, United States Grant ID: HL75026 NHLBI NIH HHS, United States Grant ID: HL56985 NHLBI NIH HHS, United States Grant ID: HL67283 NHLBI NIH HHS, United States Grant ID: HL60942 More Less keyboard_arrow_down
Preliminary study of Histamine in Rainbow trout (Oncorhynchus mykiss) samples from fish markets in Tehran

Field: Veterinary (Health Sciences)

Histidine is one of non-protein nitrogen extractives which found in fish such as Salmonidae family (trout is belonged this family).Members of this family has high amounts of Histidine compared to other foods. Some Salmon microbial flora can decarboxylated Histidine to Histamine and this metabolite is a hazard component for human. Evaluation of Histamine levels in Salmon via a fast and accurate method can be useful for decreasing the intensity of these hazards. In this study evaluated psychrophilic and mesophilic aerobic bacteria and also histamine level in purchased salmon samples from fish markets in Tehran by ELISA method (Rida Screen Histamine Kits). A total of 60 samples of Rainbow trout (Oncorhynchus mykiss) purchased from fish markets and assayed for Histamine by using Rida Screen Histamine ELISA Kits. Bacterial enumeration was performed on 10-fold diluted samples at 25°C and 35°C for mesophilic and psychrophilic bacteria, respectively. The range of Histamine content was 4 to 28mg/100g (14.18mg/100g). 12.50 percent of samples had Histamine content above the international standard level (20mg/100g). Data achieved by bacterial enumeration and ELISA test were analyzed by Pearson correlation test indicated that direct relationship between histamine and the number of bacteria in fish samples is established (p
Effects of overexpression of murine TNFɑ gene on glia and infarct volume

Field: Neuroscience (Life Sciences)

Objective: To explore the effects of overexpression of murine tumor necrosis factor-ɑ(TNFɑ) gene of Sprague-Dawley(SD) transgenic rats on glia and infarct volume in focal cerebral ischemia. Methods: Protein expression of TNFɑ and activation of microglia, astrocyte and oligodendrocyte were examined by immunohistochemistry of TNFɑ, interginɑM(OX42), glial fibrillary acidic protein(GFAP)and myelin. Using suture occlusion technique,the right middle cerebral artery in rats was occluded. SD rats and murine TNFɑ transgenic rats were subjected to 1 hour of the right middle cerebral artery occlusion.Seventy-two hours after reperfusion,neuronal deficit scores were calculated,and infarct volume was calculated by 2,3,5-triphenyltetrazolium chloride monohydrate (TTC) staining. Results: TNFɑ overexpression and hypertrophic and proliferative changes of microglia, astrocyte and oligodendrocyte in the non-ischemia brain tissue of murine TNFɑ transgenic rats were observed. Neuronal deficit scores and infarct volume of murine TNFɑ transgenic rats for after 1 hour of occlusion and 72 hours of reperfusion were higher than those of SD rats. Conclusion: Overexpression of TNFɑ gene can activate microglia, astrocyte and oligodendrocyte in the non-ischemic brain tissue, and increase neuronal deficit scores and infarct volume significantly, which suggests that it can aggravate cerebral ischemic injury.
Potentiation of 5-Fluorouracil, Chromomycin A3, and Bleomycin by Amphotericin B or Polymyxin B in Transformed Fibroblastic Cells

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

By using cultured, transformed fibroblastic cells, antitumor agents including cytosine arabinoside, thio-tepa, nitrogen mustard N -oxide, mitomycin C, chromomycin A3, 5-fluorouracil, daunomycin, vinblastine, vincristine, and bleomycin A2 were screened for the potentiation of their activity by amphotericin B or polymyxin B. Among them, the action of 5-fluorouracil and chromomycin A3 on ribonucleic acid synthesis was potentiated in their action by amphotericin B, not by polymyxin B. Bleomycin A2 was potentiated in its action on deoxyribonucleic acid and ribonucleic acid synthesis only by polymyxin B.
P332 Intra-sphincteric botulinum toxin injection in the management of functional biliary pain: is it effective?

Field: Medicine (Health Sciences)

Introduction

The management of Type III sphincter of oddi dysfunction (SOD), or functional biliary pain syndrome, remains challenging. Evidence from the EPISOD study suggests that there is no role for biliary or pancreatic endoscopic sphincterotomy in treating functional biliary or pancreatic pain.1Intra-sphincteric ampullary botulinum toxin injection has been reported to be effective in managing pancreaticobiliary pain by a combination of its anti-spasmodic effect on the sphincter of oddi and its general anti-nociceptive properties. We have been using ampullary botulinum toxin injection in conjunction with neuromodulatory drug therapy in managing functional bilio-pancreatic pain and review our experience of this management strategy.

Methods

A retrospective review of case notes over a 5-year period (2014–2019) was performed. The diagnosis of Type III SOD or functional biliary pain was made in post cholecystectomy patients following extensive laboratory, radiological and endoscopic investigations. Patients with typical pre-cholecystectomy pain, normal duct size and normal liver function tests were identified as Type III SOD or functional biliary pain, in line with the modified Milwaukee criteria. Intra-sphincteric botulinum toxin A injection was performed in a quadrantic fashion across the ampullary face. The efficacy of ampullary botulinum toxin injection on pain was recorded at post-procedure outpatient review using a nominal pain scale. Opioid analgesia and frequency of hospital admissions were noted, in addition to neuromodulatory medication initiated at the time of endoscopy or at subsequent outpatient review.

Results

119 patients (109 females, 10 males, mean age 45 (17–77) years)) with severe bilio-pancreatic pain underwent 411 intra-sphincteric botulinum toxin injection procedures (mean 2 (1–15) procedures). The median dose of botulinum toxin used was 200 (100–600) units. 43% and 55% of patients respectively were on regular or intermittent opioids for managing pain. 103 patients (87%) reported a significant improvement in pain with 77% of patients managing to discontinue opioids. 76% did not have any acute hospital admissions or emergency department attendances for pain management. 59% of the cohort were initiated on Amitriptyline (TCA), 18% onto Duloxetine (SNRI), 13% onto Pregabalin and 3% on mirtazapine (NaSSA) to treat their pain syndrome. Loss of response with the initial dose of botulinum toxin occurred in 56% of patients. Pain control was re-established in 80% of patients in this cohort following botulinum toxin injection at a higher dose to the previous o the previous effective dose. There were no procedural related complications.

Conclusions

Intra-sphincteric botulinum toxin injection is an effective and useful management strategy in conjunction with neuromodulatory agents in functional biliary pain/Type III SOD.
Narrow Band Imaging

Field: Medicine (Health Sciences)

Objective 1) Investigate a novel technology called narrow band imaging (NBI) in the detection of laryngopharyngeal reflux (LPR). 2) Compare mucosal abnormalities using NBI to conventional fiberoptic white‐light laryngoscopy. Method A prospective case‐control pilot study on the usage of NBI to identify mucosal abnormalities in patients with LPR at a tertiary referral center from July 2010 to February 2011. RFS scores were calculated using white‐light endoscopy. NBI was used to characterize endoscopic findings. Video images were reviewed by two blinded laryngologists. Results Twelve adult patients with LPR based on RSI scores and 11 normal adult controls were included. Reflux symptom index (RSI) greater than 13 and reflux finding score (RFS) greater than 11 were significantly correlated. NBI findings were graded on 2 vascular patterns and number of laryngeal sites involved. NBI was scored on a scale of 0 to 2 based on degree of color compared with background. Subsites were graded as 1 for 1 subsite and 2 for 2 or more subsites. Higher RFS were associated with lacey and punctuate patterns, as well as increased number of laryngeal sites involved. Conclusion This pilot study has demonstrated various vascularity and morphologic patterns in mucosa visualized on NBI examination of patients with LPR. Preliminary results indicate that NBI may be a useful aid in the diagnosis of LPR, but a larger study size and standardized methods of quantification of LPR changes are recommended.
Mean Field Game Theory for Agents with Individual-State Partial Observations

Field: Mathematics (Physical Sciences)

Subject to reasonable conditions, in large population stochastic dynamics games, where the agents are coupled by the system's mean field (i.e. the state distribution of the generic agent) through their nonlinear dynamics and their nonlinear cost functions, it can be shown that a best response control action for each agent exists which (i) depends only upon the individual agent's state observations and the mean field, and (ii) achieves a $ε$-Nash equilibrium for the system. In this work we formulate a class of problems where each agent has only partial observations on its individual state. We employ nonlinear filtering theory and the Separation Principle in order to analyze the game in the asymptotically infinite population limit. The main result is that the $ε$-Nash equilibrium property holds where the best response control action of each agent depends upon the conditional density of its own state generated by a nonlinear filter, together with the system's mean field. Finally, comparing this MFG problem with state estimation to that found in the literature with a major agent whose partially observed state process is independent of the control action of any individual agent, it is seen that, in contrast, the partially observed state process of any agent in this work depends upon that agent's control action.
Exploration of Patient Communication Preference Regarding Reclassified Genetic Test Results

Field: Health Professions (Health Sciences)

Genetic testing is becoming increasingly used to detect individuals who are predisposed to developing cancer. If genetic testing identifies a variant in an individual’s DNA, the testing laboratory uses available data to classify the variant as either disease-causing or benign. When limited data is available regarding a variant’s pathogenicity and the risk of cancer for an individual is not clear, the variant is classified as a “variant of uncertain significance” (VUS). If new data is discovered, the VUS may be reclassified. There is a gap in current literature regarding desired communication for a reclassified genetic test result. There are no standard guidelines for healthcare providers regarding communication of a reclassified VUS result. This study aimed to explore communication preferences of past Prisma Health patients with a VUS result on cancer genetic testing. A total of 34 participants responded to the anonymous online questionnaire. Participants reported telephone call by a genetic counselor as the most preferred communication for an upgraded VUS result and a letter in the mail as the most preferred communication for a downgraded VUS result. There was no significant difference in communication preferences for upgraded versus downgraded VUS results. A majority of participants reported mild concern regarding their VUS result. Overall, this study determined that patients want to be contacted regarding a reclassified VUS result, but there is no clear consensus on the most preferred method.
Localized performance of riblets with curved cross-sectional profiles in boundary layers past finite length bodies

Field: Engineering (Physical Sciences)

Riblets are a well-known passive drag reduction technique with the potential for as much as 9% reduction in the frictional drag force in laboratory settings, and proven benefits for large scale aircraft. However, less information is available on the applicability of these textures for smaller air/waterborne vehicles where assumptions such as periodicity and/or asymptotic nature of the boundary layer no longer apply and the shape of the bodies of these vehicles can give rise to moderate levels of pressure drag. Here, we explore the effect of riblets on both sides of a finite-size foil consisting of a streamlined leading edge and a flat body. We use high resolution two-dimensional, two-component particle image velocimetry, with a double illumination and consecutive-overlapping imaging technique to capture the velocity field in both the boundary layer and the far field. We find the local velocity profiles and shear stress distribution, as well as the frictional and pressure components of the drag force and show the possibility of achieving reduction in both the fictional and pressure components of the drag force and record cumulative drag reduction as much as 6%. We present the intertwined relationship between the distribution of the spanwise-averaged shear stress distribution, the characteristics of the velocity profiles, and the pressure distribution around the body, and how the local distribution of these parameters work together or against each other in enhancing or diminishing the drag-reducing ability of the riblets for the entirety of the body of interest.
Explorations in Semantics and Pragmatics

Field: Arts and Humanities (Social Sciences)

The aim of this book is to show the way forward to a coherent view of language in which the achievement of the formalist paradigm is strengthened to the extent that its claims are weakened. A formal theory such as generative grammar is a special theory which is to be subsumed in a general theory of linguistic communication that also includes pragmatics. The tension between the psycho-formalist and the socio-functional views could be resolved in a synthesis whereby both the psychological and social natures of language are fully acknowledged. Semantics and pragmatics, representing these two natures in the study of meaning, have distinct goals, which can be defined more clearly and pursued more effectively to the extent that both their distinctness and their interdependence are recognized.
Origin and development of exocrine pancreatic insufficiency in experimental renal failure.

Field: Medicine (Health Sciences)

Chronic renal failure affects the physiological function of many organ systems. One of them is the exocrine pancreas. Although varying degrees of pancreatic insufficiency are the dominating clinical characteristic of uraemic pancreatic disease, it remains unclear whether this disease should be regarded as a manifestation of chronic pancreatitis, arising from recurring attacks of acute pancreatitis, or represents a distinct entity. The exocrine pancreas was studied in a model of experimental renal failure. The pancreas was removed from each rat at selected time points over eight weeks after subtotal nephrectomy and from a standard rat model of pancreatitis for comparison. The data show that the in vitro secretory response is considerably changed in renal failure (increased during early acute and decreased during chronic renal failure). While the pancreatic content of digestive enzymes progressively declines, DNA and protein synthesis increase over time. Acinar cell deletion is increased and accompanied by an increased rate of mitosis. This increased cellular turnover is not associated with tissue oedema, pancreatic fibrosis, inflammatory changes, autophagocytosis or subcellular redistribution of lysosomal hydrolases, all of which are characteristic for pancreatitis. The ultrastructural changes of uraemic pancreatic disease bear no resemblance to the changes seen in pancreatitis. It is concluded that the morphological and biochemical changes in early uraemic pancreatic disease are quite distinct, correspond with toxic damage of the pancreas, and are dominated by functional impairment and an increased cellular turnover.
Differential Informativeness of Accrual Measures to Analysts’ Forecast Accuracy

Field: Economics, Econometrics and Finance (Social Sciences)

This paper evaluates whether analysts incorporate formal measures of earnings quality into their earnings forecasts. It examines whether the accrual ratio and abnormal accruals, measured with the Modified Jones (1991) Model of discretionary accruals, differentially inform analysts’ earnings forecasts. It uses the accuracy of analysts’ forecast as a context in which to evaluate how well analysts incorporate effects of the information contained in accrual ratio and abnormal accruals. The results indicate that the accrual ratio is negatively related to the absolute value of analysts’ forecast errors while the Modified Jones (1991) Model of discretionary accruals have virtually no economic effect on analysts’ forecast error. The insignificant effect of discretionary accruals on analysts’ forecast may be attributed to analysts having already incorporated the information therein in their earnings forecasts, effect of the accrual anomaly having been largely arbitraged away by market participants or both. This paper contributes to the research on analysts’ earnings forecast and earnings quality and helps bridge the gap between practice and theory by demonstrating the differential impact of discretionary accruals (favored by academics) and the accrual ratio (favored by analysts) on analysts’ forecast accuracy. This study informs researchers and policy makers interested in better understanding how analysts affects the financial markets including how they may have learned from previously documented market anomalies such as the accrual anomaly. This is important as ultimately, efficient economy-wide capital allocation decisions are based partly on outputs of analysts’ forecasting processes.