jimnoneill/paper-to-field-training huggingface dataset:
Application of Extended Messinger Models to Complex Geometries

Field: Engineering (Physical Sciences)

<div class="section abstract"><div class="htmlview paragraph">Since, ice accretion can significantly degrade the performance and the stability of an airborne vehicle, it is imperative to be able to model it accurately. While ice accretion studies have been performed on airplane wings and helicopter blades in abundance, there are few that attempt to model the process on more complex geometries such as fuselages. This paper proposes a methodology that extends an existing in-house Extended Messinger solver to complex geometries by introducing the capability to work with unstructured grids and carry out spatial surface streamwise marching.</div><div class="htmlview paragraph">For the work presented here commercial solvers such as STAR-CCM+ and ANSYS Fluent are used for the flow field and droplet dispersed phase computations. The ice accretion is carried out using an in-house icing solver called GT-ICE. The predictions by GT-ICE are compared to available experimental data, or to predictions by other solvers such as LEWICE and STAR-CCM+. Three different cases with varying levels of complexity are presented. The first case considered is a commercial transport airfoil, followed by a three-dimensional MS(1)-317 swept wing. Finally, ice accretion calculations performed on a Robin fuselage have been discussed. Good agreement with experimental data, where applicable, is observed. Differences between the ice accretion predictions by different solvers have been discussed.</div></div>
Review Symposium: Punishing the Poor: The Neoliberal Government of Social Insecurity. By Loic Wacquant (Durham, NC: Duke University Press, 2009, 384pp. 58.99 hb, 11.65 pbk): Reviews by Joe Sim, Barbara Hudson, Desmond King, Magnus Hornqvist and Alessandro De Giorgi

Field: Social Sciences (Social Sciences)

From castles and palaces and churches to prisons and workhouses and schools; from weapons of war to a controlled press, any ruling class, in variable ways though always materially, produces a social and political order. (Raymond Williams, cited in Gunvald Nilsen 2009: 115)
Online social networking addiction and depression: The results from a large-scale prospective cohort study in Chinese adolescents

Field: Psychology (Social Sciences)

Background and aims The aim of this study is to estimate the longitudinal associations between online social networking addiction (OSNA) and depression, whether OSNA predicts development of depression, and reversely, whether depression predicts development of OSNA. Methods A total of 5,365 students from nine secondary schools in Guangzhou, Southern China were surveyed at baseline in March 2014, and followed up 9 months later. Level of OSNA and depression were measured using the validated OSNA scale and CES-D, respectively. Multilevel logistic regression models were applied to estimate the longitudinal associations between OSNA and depression. Results Adolescents who were depressed but free of OSNA at baseline had 1.48 times more likely to develop OSNA at follow-up compared with those non-depressed at baseline [adjusted OR (AOR): 1.48, 95% confidence interval (CI): 1.14–1.93]. In addition, compared with those who were not depressed during the follow-up period, adolescents who were persistently depressed or emerging depressed during the follow-up period had increased risk of developing OSNA at follow-up (AOR: 3.45, 95% CI: 2.51–4.75 for persistent depression; AOR: 4.47, 95% CI: 3.33–5.99 for emerging depression). Reversely, among those without depression at baseline, adolescents who were classified as persistent OSNA or emerging OSNA had higher risk of developing depression compared with those who were no OSNA (AOR: 1.65, 95% CI: 1.01–2.69 for persistent OSNA; AOR: 4.29; 95% CI: 3.17–5.81 for emerging OSNA). Conclusion The findings indicate a bidirectional association between OSNA and depression, meaning that addictive online social networking use is accompanied by increased level of depressive symptoms.
A STUDY ON THE PLANNING AND MANAGEMENT OF THE CENTRAL STERILE SUPPLY DEPARTMENT IN ACUTE HOSPITAL HAVING INSTALLED OFF-SITE STERILIZATION SERVICE

Field: Health Professions (Health Sciences)

This paper describes the characteristics of planning and management of central sterile supply department (C.S.S.D.) in acute hospital having installed off-site sterilization service. We concluded the following points. .1) Hospitals having installed off-site sterilization service conduct a high number of surgical procedures in relation to the number of beds. At C.S.S.D., management and rational maintenance of cleaning and sterilization machines, are being conducted in accordance with the situation. .2) As fit economic conditions, cleaning, sterilization and responsibilities could be allocated between C.S.S.D. and off-site sterilization service center to make it possible to plan and maintain the machines of simpler C.S.S.D.
Dynamic Gesture Recognition Based On Multimodal Fusion Model

Field: Computer Science (Physical Sciences)

Aiming at the problem that the RGB modal is susceptible to illumination, skin color, complex background, and lack of motion information, resulting in low recognition accuracy. A dynamic gesture recognition algorithm based on the joint ResNeXt-3D-CBAM model is proposed. The algorithm uses a 3D convolution kernel to replace the traditional 2D convolution kernel in the ResNeXt network, and effectively extracts the spatiotemporal features of dynamic gestures in RGB, Depth and optical flow data. Then use the method of multi-model fusion to predict dynamic gestures. Experimental results show that the method proposed in this paper can recognize dynamic gestures more accurately. Compared with the traditional single-modal information, the accuracy of dynamic gesture recognition is improved, which verifies the feasibility and superiority of the proposed method.
Why and what in Early Modern English drama

Field: Arts and Humanities (Social Sciences)

This study sheds new light on the nature of the discourse markers why and what in the Early Modern English (EModE) period. It attempts to fill a gap by providing a contrastive analysis of these two markers of similar origin in the drama samples of two EModE corpora – A Corpus of English Dialogues 1560–1760 and the Penn-Helsinki Parsed Corpus of Early Modern English – covering the time span 1500 to 1760. The discourse markers are approached from a quantitative and a qualitative perspective, so as to account for their frequency of attestation as well as their functions, with the aim of reaching a deeper understanding of the potential similarities and differences in their use and development in the course of the EModE period.
NIF PEPC LRU Test Stand Safety Note Addendum

Field: Engineering (Physical Sciences)

It is necessary that the NIF PEPC LRU Test Stand be modified to accommodate a new experiment. This modification will involve boring two 1/2 inch holes in the Center Loaded Upper Beam of the stand. These holes will allow a small wire to pass through half of the length of one of the long sections of 80/20 part 3030. The holes could adversely effect the load-bearing capabilities of an important structural member of the stand so calculations must be done to assure a minimal risk of part failure.
Large-scale underground construction risk assessment using decision aids for tunneling (DAT)

Field: Decision Sciences (Social Sciences)

The Final Year Project (FYP) covers the need for risk analysis, types of risk particularly in construction projects, and further discusses on the use of the Decision Aids for Tunneling (DAT) for underground construction projects. It includes the review of basic underground construction methods, and goes further in depth to share the process of the DAT simulation. In this report, the risk analysis of an ongoing large scale underground project will be carried out via the DAT simulation. Steps wise procedure in the DAT simulation will be carefully explained in Chapter 3, and the results are then compared with the results from @Risk, a generic risk analysis program that has been used more commonly, but is unable to achieve a holistic risk analysis for large scale underground projects. Finally, after studying the risk analysis results from both DAT and @Risk, the potentials of DAT will be discussed.
New Distributional Record for Siganus vermiculatus (Valenciennes 1835) from the Veraval Fishing Landing Centre along Northwest Coast of India

Field: Agricultural and Biological Sciences (Life Sciences)

A new distributional record of vermiculated spinefoot, (Valenciennes, 1835), belonging to the family Siganus vermiculatus Siganidae, for the first time from the northwest coast of India at Veraval fish landing centre (20 54'03" N 70 22' 10" E) in Gir-Somnath district of 0 0 the state of Gujarat on 23 March 2022.The morphometric and meristic characters of the specimen were measured using standard taxonomic keys.Further, DNA barcoding was carried out for the mitochondrial cytochrome oxidase subunit I gene from the tissues of the holotype specimen and phylogenetic studies using neighbor joining tree construction were done to ascertain the relationship and similarity with the specimens of the same species barcoded in the other places of southern India, and authentication of the specimens to was S. vermiculatus done.The species is reported from 900 km north of the previous nearest reported location.
Lack of Introns in the Ribosomal Protein Gene S14 of Trypanosomes

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Introns are almost always present in ribosomal protein genes, even in organisms in which introns are rare. Although trans spliced, the trypanosome ribosomal protein gene S14 apparently does not have cis introns, which supports the notion that such introns are absent in this organism.
HUBUNGAN BERAT BADAN LAHIR RISIKO (<2500gr DAN >4000gr) DENGAN ASFIKSIA NEONATORUM DI RSD MAYJEN HM RYACUDU KOTABUMI LAMPUNG UTARA

Field: Medicine (Health Sciences)

WHO (World Health Organization) reports that neonatorum asphyxia deaths in Indonesia amounted to 29.9% reported to occur on the first life, and 75.6% on the week after birth. In Lampung, there were 47 events per 1000 in 2017. The purpose of this research was to fine the relationship of Birth Weight with the Asphyxia in Neonaturum. The research method uses descriptive analytic design, with cross sectional approach. The population was all neonatus in 2017 in the neonate room and VK in HM Ryacudu Mayjend Kotabumi, North Lampung Hospital were 820 babies. 269 samples were taken by random sampling technique. The results obtained pvalue 0.003 means pvalue α, it is concluded there is a relationship between birt weight with asphyxia. An OR value of 2.2, which means neonates born with birth weight (2500 grams and 4000 grams) have a 2.2-fold potential to occur asphyxia neonaturum compared to unweighted birth weight. Asphyxia neonatorum can be avoided by maintaining the weight of the baby during normal wombs, so mothers are expected to have their health checked routinely during pregnancy.
DNA sequencing of formalin-fixed crustaceans from archival research collections.

Field: Agricultural and Biological Sciences (Life Sciences)

Marine invertebrate collections have historically been maintained in ethanol following fixation in formalin. These collections may represent rare or extinct species or populations, provide detailed time-series samples, or come from presently inaccessible or difficult-to-sample localities. We tested the viability of obtaining DNA sequence data from formalin-fixed, ethanol-preserved (FFEP) deep-sea crustaceans, and found that nucleotide sequences for mitochondrial 16S rRNA and COI genes can be recovered from FFEP collections of varying age, and that these sequences are unmodified compared with those derived from frozen specimens. These results were repeatable among multiple specimens and collections for several species. Our results indicate that in the absence of fresh or frozen tissues, archived FFEP specimens may prove a useful source of material for analysis of gene sequence data by polymerase chain reaction (PCR) and direct sequencing.
Pulmonary lesions associated with busulfan therapy of chronic myelogenous leukemia

Field: Medicine (Health Sciences)

The pulmonary findings in 40 patients treated with busulfan were compared with those in 41 patients with chronic myelogenous leukemia who were treated with other agents or were untreated. Cellular atypia characteristic of busulfan effect was found in 4 patients but only one of these had pulmonary fibrosis and associated respiratory distress (the “busulfan lung syndrome”). Dysplasia of the bronchial epithelium was present in half of the busulfan-treated group but in only 15% of the control group. Other pulmonary changes were seen with equal frequency in both groups. In order to compare the relative susceptibility of the lung to busulfan, the pancreas from each case was examined for evidence of cellular atypia. Seventy-three per cent of the pancreases from busulfan-treated patients were distinguishable on the basis of acinar cell nuclear alterations.
Lifelogging as a rehabilitation tool in patients with amnesia: A narrative literature review on the effect of lifelogging on memory loss

Field: Health Professions (Health Sciences)

Visual lifelogging is the procedure that enables individuals to visually record daily life activities by means of small wearable cameras, which can be worn around the neck or on the clothing. Lifelogging devices automatically take pictures or videos after pre-set time intervals or after dynamic input changes. Although some studies have shown effectivity of reviewing lifelogging images in brain-damaged individuals with forms of amnesia as a rehabilitation tool, systematic endeavours to overview this literature is yet missing. The aim of this narrative literature review was to review all the available case-studies, experimental studies and group studies in brain-damaged individuals applying lifelogging devices in a clinical context. The included studies showed efficacy for both subjective and objective measures of memory. In mild to severe amnesia, reviewing images recorded by the lifelogging device was beneficial to subjective and objective measures of memory. Lifelogging is demonstrated to have a great potential in helping people who are suffering from memory loss. It can offer an excellent alternative to currently more frequently used memory rehabilitation techniques and can be applied more in clinical settings.
(Invited) Electro-Thermal Characterization of SiGe HBT PA-Cells

Field: Engineering (Physical Sciences)

This paper investigates electrical performances of two different transistor array configurations operating as 60GHz power amplifier cells. Maximum RF power gain and a maximum PAE are determined using a load-pull measurement set-up. The electrical and thermal behavior between multi-finger transistor and multi-transistor array are compared. Drawbacks and advantages of each structure are discussed and the current preference of the usage of multi-emitter structures versus multi-transistor structures is questioned.
Strong lensing time-delay cosmography in the 2020s

Field: Physics and Astronomy (Physical Sciences)

Abstract Multiply imaged time-variable sources can be used to measure absolute distances as a function of redshifts and thus determine cosmological parameters, chiefly the Hubble Constant H $$_0$$ 0 . In the two decades up to 2020, through a number of observational and conceptual breakthroughs, this so-called time-delay cosmography has reached a precision sufficient to be an important independent voice in the current “Hubble tension” debate between early- and late-universe determinations of H $$_0$$ 0 . The 2020s promise to deliver major advances in time-delay cosmography, owing to the large number of lenses to be discovered by new and upcoming surveys and the vastly improved capabilities for follow-up and analysis. In this review, after a brief summary of the foundations of the method and recent advances, we outline the opportunities for the decade and the challenges that will need to be overcome in order to meet the goal of the determination of H $$_0$$ 0 from time-delay cosmography with 1% precision and accuracy.
An Engineered Cargo-Transport Molecular Motor Composed of a Kinesin Monomer and a Diffusing Microtubule-Associated Protein

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

An engineered molecular motor composed of an ATP-dependent kinesin-1 monomer and an ATP-independent diffusing microtubule-associated protein is proposed, and its dynamics are studied theoretically. It is shown that the engineered motor can move directionally on microtubules towards the plus end, bearing great potential for applications in therapeutics or nanorobotics. The engineered motor can have an unloaded velocity similar to the wild-type kinesin-1 dimer, can take a mechanical (either forward or backward) step by hydrolyzing an ATP molecule under any load, and can generate the maximum force that is about half of that generated by the wild-type kinesin-1 dimer.
Transcriptional regulation of endothelial Arginase 2 by Histone Deacetylases and its role in atheresclerosis

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

A critical event in the development of endothelial dysfunction (ED) in atherosclerosis is elevated arginase (ARG) expression and activity that results in local L‐arginine depletion and nitric oxide synthase (NOS) uncoupling, which ultimately leads to nitros‐redox imbalance in the endothelial cells (EC) and ED. There is significant deficit in knowledge regarding mechanism underlying increased ARG expression in cardio vascular diseases (CVD). Inhibition of Histone Deacetylases (HDACs) increase histone acetylation that results in increased transcriptional accessibility and therefore increased gene expression. Recent findings have implicated HDAC3, 5 and 7 in VEGF signaling, EC proliferation, survival and growth suggesting its role in CVD. In our current study, human aortic endothelial cells (HAEC) and isolated mice aortic rings exposed to broad HDAC inhibitor, Trichostatin A (TSA) elicited a robust increase in ARG2 (ARG2) protein and mRNA expression. Aortic rings exposed to 200nM of TSA for 8 hours resulted in almost 50% reduction in acetylcholine‐mediated relaxation, which was significantly restored with ARG2 inhibitor. We have also found robust increase in ARG2 promoter activity in EC treated with TSA suggesting that TSA is important in transcriptional regulation of ARG2. Taken together, these studies will allow us to determine whether HDAC represents a novel target for the effective treatment of CVD.
A framework and pragmatic strategies for transit priority implementation

Field: Engineering (Physical Sciences)

Bus lanes, traffic signals for trams, and many other measures can be used to prioritise on-road public transport services. Because buses and trams can carry people very efficiently there is often a strong case for advantaging them over other traffic, particular in congested urban areas. However, converting traffic lanes, removing on-street parking and other changes can mean that transit priority measures that are appropriate from an engineering perspective are often politically, institutionally or publicly unpopular. This research examines public transport priority through the lenses of legitimacy theory and public policy analysis, and develops pragmatic strategies for implementation in car-centric cities.
Glycans, Glycosite, and Intact Glycopeptide Analysis of N-Linked Glycoproteins Using Liquid Handling Systems

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Aberrant glycosylation has been shown to associate with disease progression, and with glycoproteins representing the major protein component of biological fluids this makes them attractive targets for disease monitoring. Leveraging glycoproteomic analysis via mass spectrometry (MS) could provide the insight into the altered glycosylation patterns that relate to disease progression. However, investigation of large sample cohorts requires rapid, efficient, and highly reproducible sample preparation. To address the limitation, we developed a high-throughput method for characterizing glycans, glycosites, and intact glycopeptides (IGPs) derived from N-linked glycoproteins. We combined disparate peptide enrichment strategies (i.e., hydrophilic and hydrophobic) and a liquid handling platform allowing for a high throughput and rapid enrichment of IGP in a 96-well plate format. The C18/MAX-Tip workflow reduced sample processing time and facilitated the selective enrichment of IGPs from complex samples. Furthermore, our approach enabled the analysis of deglycosylated peptides and glycans from enriched IGPs following PNGase F digest. Following development and optimization of the C18/MAX-Tip methodology using the standard glycoprotein, fetuin, we investigated normal urine samples to obtain N-linked glycoprotein information. Together, our method enables a high-throughput enrichment of glycan, glycosites, and IGPs from biological samples.
The State of Knowledge in Rural Gifted Education: A Systematic Literature Review

Field: Social Sciences (Social Sciences)

To outline the current state of empirical knowledge in rural gifted education, a systematic review of the international empirical literature was conducted with peer-reviewed journal articles published from 2000 to 2020. Six inclusion/exclusion criteria guided the searches that were undertaken of the ERIC and PsycINFO databases, six peer-reviewed journals in gifted education, and three peer-reviewed journals in rural education, along with the reference lists of the journal articles identified from the database and journal searches. The 103 journal articles that were eventually identified as meeting search criteria were thereafter analyzed to document key details, including the countries/regions of origin, publication outlets, authorship, approaches to data collection and analyses, and the major findings. A discussion of the key issues and trends in the identified studies, along with areas for focus in future investigations, concludes the review.
Synthesis of 9‐Halogenated 9‐Deazaguanine N7‐(2′‐Deoxyribonucleosides)

Field: Chemistry (Physical Sciences)

Abstract The syntheses of N 7 ‐glycosylated 9‐deazaguanine 1a as well as of its 9‐bromo and 9‐iodo derivatives 1b , c are described. The regioselective 9‐halogenation with N ‐bromosuccinimide (NBS) and N ‐iodosuccinimide (NIS) was accomplished at the protected nucleobase 4a (2‐{[(dimethylamino)methylidene]amino}‐3,5‐dihydro‐3‐[(pivaloyloxy)methyl]‐4 H ‐pyrrolo[3,2‐ d ]pyrimidin‐4‐one). Nucleobase‐anion glycosylation of 4a – c with 2‐deoxy‐3,5‐di‐ O ‐( p ‐toluoyl)‐α‐ D ‐ erythro ‐pentofuranosyl chloride ( 5 ) furnished the fully protected intermediates 6a – c ( Scheme 2 ). They were deprotected with 0.01 M NaOMe yielding the sugar‐deprotected derivatives 8a – c ( Scheme 3 ). At higher concentrations (0.1 M NaOMe), also the pivaloyloxymethyl group was removed to give 7a – c , while conc. aq. NH 3 solution furnished the nucleosides 1a – c . In D 2 O, the sugar conformation was always biased towards S (67–61%).
Supplementary Tables 1 through 4 and Supplementary Figures 1 and 2 from Identification of Novel Fusion Genes in Testicular Germ Cell Tumors

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

<p>Supplementary Table S1: primers used in RT-PCR and qRT-PCR validation and quantification of fusion genes and transcripts. Supplementary Table S2: Primers and probes for assays used in ddPCR linkage experiments. Supplementary Table S3: Pairs of sequencing reads. Supplementary Table S4: Candidate fusion transcript breakpoints validated by RT-PCR. Supplementary Figure S1: Sanger sequencing electropherograms validating fusion transcript breakpoints. Supplementary Figure S2: Milepost ddPCR linkage results of DNA from the NCI-H508, NTERA2 and 833KE cell lines.</p>