jimnoneill/paper-to-field-training huggingface dataset:
An investigation of the role of the S. cerevisiae RNA-binding protein Scp160p/vigilin in the aggregation of Q/N-rich proteins

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The vigilin family of RNA-binding proteins are highly conserved from yeast to mammals. Work from various organisms have linked vigilin to a multitude of cellular processes both in the nucleus and cytoplasm. These processes include ploidy maintenance, heterochromatin formation, as well as regulation of processing-body formation, mRNA localization, translation, and stability. Our lab has previously reported a role for the Saccharomyces cerevisiae vigilin homolog, Scp160p, in promoting the reuse of tRNAs in the context of codon composition. This work explores this role further by assessing how loss of Scp160p affects biosynthesis of aggregation-prone polyglutamine (polyQ) reporters that differ in their codon usage. Microscopy and biochemical analysis show that aggregation of the polyQ reporters is reduced in scp160Δ cells, regardless of codon usage. This effect on protein aggregation was further assayed for the endogenous S. cerevisiae proteome by combining filter-trap binding, to capture SDS-resistant aggregated proteins, and quantitative mass spectrometry by dimethyl labelling. Such an analysis revealed that aggregation of many polyQ and glutamine/asparagine-rich (Q/N-rich) proteins, including the transcription factor Cyc8p and RNA-binding protein Nab3p, were reduced in the absence of Scp160p. Additional work preliminarily suggests that loss of Scp160p may perturb translation kinetics, thereby influencing co-translational folding and likelihood of protein aggregation. In this way, Scp160p may influence many cellular processes by modulating Q/N-mediated protein aggregation.
Physical activity influences heart rate variability in young adults, regardless of dextrose ingestion

Field: Medicine (Health Sciences)

Introduction: Cardiac autonomic modulation can be altered by carbohydrate ingestion. On the other hand, some of the protective effects of physical activity may be due to its impact on the autonomic nervous system. Purpose This cross-sectional study was conducted to evaluate whether physical activity level influences heart rate variability (HRV) under fasting and mainly, after dextrose ingestion. Methods Healthy adults aged 18–40 years ( n = 92; 54.35 % women) were separated into nonactive ( n = 47) and active groups ( n = 45), based on the physical activity level determined by International Physical Activity Questionnaire (IPAQ) and then compared. Results There were no significant differences ( P > 0.05) for age, body mass, BMI, abdominal circumference, blood pressure, fasting glucose and blood glucose at 60 min after dextrose ingestion between groups. Body fat (%) was lower in the active group ( P = 0.02). The time-domain indices (RMSSD, SDNN and pNN50) were higher in the physically active group compared to the nonactive group (main effect of group, P < 0.01). The SDNN index was higher at 60 min after dextrose ingestion compared to fasting (main effect of time, P ≤ 0.01). However, no HRV indices showed significantly interaction effect (group x time; P > 0.05). Conclusion The magnitude of HRV responses to glucose was not influenced by physical activity status. Young adults who met at least the minimum physical activity recommendations showed a higher cardiac autonomic modulation, regardless of dextrose ingestion.
COMPARISON OF CHEMICAL COMPOSITION AND ANTIBACTERIAL ACTIVITY OF MENTHA PULEGIUM ESSENTIAL OIL FROM TWO ECOTYPES (EL BAYADH AND DJELFA)

Field: Agricultural and Biological Sciences (Life Sciences)

Mentha pulegium, collected from two different sites in Algerian high plains (El Bayadh and Djelfa), were analyzed to determine essential oil constituency. Essential oils were extracted by hydrodistillation and subsequently analyzed by GC and GC/MS. Quantitative differences were recorded between the percentages of some constituents between plants from the two geographical origin. The most important major components were: 1,8-cineole, menthone, menthol, cis-Pulegone and Pulegone. The antimicrobial activity of the essential oils was tested using the disc-diffusion assay. The results showed that the essential oil of Mentha pulegium had great potential of antibacterial activity against selected bacteria
A Brief Discussion on Pre-internship Training about Pharmacy Moral and Professional Skills for Higher Vocational Pharmacy Majors

Field: Health Professions (Health Sciences)

Practice is the final training stage for higher vocational pharmacy students.Therefore,the training of pharmacists' professional ethics,familiarity of internship units regulations and post duty,definite internship goal and contents should be emphasized before practice.At the same time four aspects skills including prescription dispensing,preparations,drug analysis,drug maintenance should be strengthened.
Anatomical description of the ventral and dorsal cervical rootlets in rats: A microsurgical study

Field: Neuroscience (Life Sciences)

This investigation was the first to study cervical rootlets in rats. In 20% of the sample studied, the dorsal root of C1 was absent mainly on the left side. There is a nonlinear numerical increase from C1 to T1 in the rootlets. There is a numerical predominance of cervical fascicles on the left side, confronting several studies related to the functional predominance of right laterality, requiring new studies that correlate these variables.
"Playing with autobiography" The performer as biographer: Viktor Ullmann’s Piano Sonata No. 7 (1944)

Field: Arts and Humanities (Social Sciences)

Viktor Ullmann’s Jewish ancestry resulted in his deportation to Terezín concentration camp in 1942, where he wrote Piano Sonata No. 7 within three months of his death in Auschwitz in October 1944. This research focuses on the interpretation of Ullmann’s score as an autobiographical text, and how performance decisions will affect the sense of Ullmann’s ‘self’ presented to the audience, just as a biographer’s literary choices affect a reader’s interpretation of its subject. Additional material(s) submitted with thesis.
Linking biodiversity, ecosystem services and social actors to promote agroecological transitions

Field: Environmental Science (Physical Sciences)

The landscape in Zona da Mata region (Brazil) can be understood as a dynamic mosaic of land uses, including secondary forest, pastures and coffee. Spatial patterns of such mosaics are determined by heterogeneous physical landscape features and shaped by the diversity in management practices and decisions made by individual farmers. Thus, a gradient of more biodiverse to overly simplified farms can be found in the region. These farming systems contribute differently to local livelihoods and to the provision of ecosystem services (ES). Currently, we lack understanding of the incentives that farmers have to manage agrobiodiversity and the consequences of management for functional diversity and the provision of multiple ES. Therefore, I used a combination of social and ecological methods to link biodiversity, ecosystem services and social actors for informing the development of sustainable agroecological systems. First, a farm typology was conducted in the region to explore implications of farm diversity for promoting agroecology and agrobiodiversity. Second, fuzzy cognitive maps were used to unravel and contrast farmers` perceptions on ecosystem services and their management. Third, coffee and pastures were selected on different farm types to evaluate the direct and indirect impact of management on biodiversity and ecosystem services. A variety of indicators were measured in each system and grouped in three components: soil-based ecosystem services; plant diversity (taxonomical, functional and structural); and management practices. Fourth, the effects of forest regeneration on biodiversity and soil functions was assessed along a successional gradient in the Atlantic forest biome. The results show that changes in the cognitive perception of farmers on ES led to changes in management strategies, that in turn, influenced biodiversity and the provision of ES. Agroecological farmers had a more complex perception on ES than other farm types, which was associated to greater access to public policies and participation in social organisations as well as higher biodiversity in their agroecosystems. Thus, the transition to agroecology in Zona da Mata was successful to help a group of a farmers to enhance biodiversity based ecological processes, moving away from the dependence of industrial inputs without compromising soil quality and plant health. In addition, I demonstrated the potential of secondary forest succession as an strategy to help farmers to increase on-farm forest cover and recover the associated biodiversity and soil functions. The outcomes from this thesis were useful both to answer more fundamental research questions and also to support land users, managers, policy-makers, technicians and other actors to take informed decisions based on a multilevel scientific assessment of agroecosystems.
African American Health Equity

Field: Health Professions (Health Sciences)

The field of health disparities and subsequently health equity has origins in the study of differences in health status and outcomes between African American and White populations. As a result, the literature surrounding health disparities and health equity among African Americans is arguably the most robust of any population-specific health disparity group. African American populations remain severely impacted by macrolevel structural issues that lead to many health disparities. This chapter summarizes the multilevel factors influencing the presence of health disparities for African Americans. It also summarizes several of the most studied disparities, examining the cause-specific health determinants, outcome disparities, and cause-specific recommendations for intervention and prevention work. The chapter describes the ways in which social determinants of health play a role in the existence and persistence of African American health disparities. It concludes with a discussion of specific approaches to advance health equity among African Americans.
Knowledge of the Use of Radiation among Urology Residents

Field: Health Professions (Health Sciences)

Objective: Describe the knowledge in the use of radiation by residents of urology. Censor formal education about the
correct use of radiation and know the percentage of residents who inform their patients of the exposure to ionizing
radiation. Methods: Observational, transversal, multicenter. The survey prepared by Jindal, 2015, with prior authorization of
the author. They were integrated and analyzed the data by the SPSS platform.
Result: 62 surveys, 81% have completed at least 3 years of residence. 100%. They are subjected to radiation during
their formation. 56.45% are submitted between 1 and 5 procedures a week. 98% of residents use some protection
devices. The more used is the vest with 100%, The 9.68% use dosimeters. 85% of residents do not receive any formal
training or class. 40.32% of residents never inform their patients that they will be exposed to radiation. Conclusion: The data obtained are comparable with the residents of India, Europe, and the United States. The
patient should be informed that radiation will be used. Formal education and training in the use, protection and
effects of ionizing radiation from urologists information represent an area of opportunity for the restructuring of the
education programs.
Optimization of additive contents in cottonseed meals during the solid-state fermentation using response surface methodology and artificial neural network-based genetic algorithm

Field: Agricultural and Biological Sciences (Life Sciences)

The response surface methodology(RSM) and an artificial neural network-based genetic algorithm(ANN-GA) were carried out to investigate the effects of urea content,Na2CO3 content and rapeseed meal content on free gossypol detoxification from cottonseed meals by solid-state fermentation.The modeling and optimizing abilities of the two methods were compared.The results showed that according to RSM,the optimal additive contents for free gossypol detoxification were 0.97% urea,2.47% Na2CO3 and 24.32% rapeseed meal,and the predicted detoxification and experimentally measured detoxification ratios were 77.71% and 79.10%,respectively.Among the three factors,Na2CO3 content had the biggest effect on free gossypol detoxification.According to the ANN-GA method,the maximum detoxification ratio of 81.36% was predicted when the urea content,Na2CO3 content and rapeseed meal content were 0.98%,2.45% and 23.66%,respectively.While the experimentally measured detoxification ratio was 80.09%.The correlation efficiency of 0.9191 identified by response surface methodology was a little lower than that of 0.9991 identified by genetic algorithm based on an artificial neural network model,which also was with a lower RMSE value by 0.13,indicating that the artificial neural network-based genetic algorithm had a much higher optimizing ability and modeling ability during the optimization of the solid-state fermentation process.
Habermas and Religious Communication: The Insufficiency of the Translation Proviso

Field: Arts and Humanities (Social Sciences)

Much has been debated and written about the translation proviso, its implications, and its rationality. At its core, it is about communication and a transition in religious communication that means it can become secularly engaged. This paper argues that the theory of the translation proviso is insufficient to accommodate religious communication and, in order to support the arguments made, considers associated aspects of the work of Habermas, such as solidarity, tolerance and universalism, as well, of course, as communication. Considerations in this wider context lead to a growing awareness that the translation proviso and its prescriptive tendencies may be seen as being an ominous contradiction of much of the other work of Habermas and that, far from being postmetaphysical and postmodern, it may have elements of being a ‘big idea’.
Melding theoretical perspectives: a gendered look at low-resting heart rate and developmental trajectories of antisocial behavior

Field: Psychology (Social Sciences)

The biosocial theoretical perspective is a growing area within criminological theory; however, skepticism remains toward such new research endeavors. Uncertainty may come from a perceived lack of connection to existing theories of criminality and/or the apparent resources required in conducting biosocial research. Therefore, the aim of this study was twofold. First, by utilizing the public version of National Longitudinal Study of Adolescent Health (Add Health) data, this study provides an example of biosocial research that does not require the use of expensive laboratory equipment or restrictive datasets. Second, by utilizing a sample of 1629 individuals followed from age 13 to 29, a longitudinal latent class analysis was estimated to explore the relationship between low-resting heart rate and antisocial behavior for both males and females. Doing so, the current study integrates a well-researched correlate of biosocial criminology with mainstream criminological theories (i.e. developmental theories), while also employing a fairly novel approach to group-based trajectory modeling.
Bridging the divide by screencasting in an introductory statistics class at an Australian university

Field: Decision Sciences (Social Sciences)

Emerging technologies are being used increasingly to improve the communication and quality of instruction in the statistics classroom. Whereas a decade ago the move commenced away from blackboard writing with chalk towards computer assisted lecture delivery via PowerPoint or Beamer presentations, we are now seeing increasing use of Tablet technology to create dynamic and engaging lectures. While usually only students physically attending lectures would benefit, combined with screencasting – video capturing of the full computer screen along with audio recording – a near live lecture experience can be provided to students who cannot attend lectures. This is particularly valuable at universities with students enrolled in distance mode. This study investigates the benefits and downsides of providing lecture screencasts to oncampus and distance students of an introductory statistics class at the University of Southern Queensland (USQ). After technical issues were overcome, the recorded lectures were well received by the students, and this anecdotal evidence is supported by positive student evaluations.
Bioisolation on the Space Station of Mice and Men

Field: Engineering (Physical Sciences)

<div class="htmlview paragraph">The results of three months of testing using rodents in a breadboard biological isolator cage are presented. These cages are designed to provide isolation using microbial air filters on both inlet and outlet. Four different types cf filters were tested: a conventional HEPA filter (rated at 99.97% efficient at 0.3 microns), a “hospital” grade HEPA filter (95% efficient at 0.3 microns), and two grades of “Filtrete” - a proprietary 3M polypropylene material (rated at 84% and 97.3%, respectively, at 0.3 microns). Test results showed excellent performance on all filters, meeting or exceeding the strict particulate and microbial air quality standards proposed for the outlet of the animal holding facility: Class 100 and 10 Colony Forming Units (CFU)/m<sup>3</sup>. In addition, it was also discovered that the fiberglass batting used inside the cage to contain animal waste served as an effective microbial filter by itself.</div>
SEASONAL VARIATION OF INDOOR AIR QUALITY IN CLASSROOMS OF A 1970s CONVENTIONAL, A PRE-PASSIVHAUS AND A PASSIVHAUS PRIMARY SCHOOL BUILDINGS IN THE UK

Field: Environmental Science (Physical Sciences)

A number of studies argued that poor indoor air quality (IAQ) in primary school classrooms can have a\nmeasurable impact on the concentration and learning ability of pupils (Bakó-Biró et al, 2012). As\nchildren’s academic performance is seen to decrease in deprived areas in the UK, the classroom\nenvironment needs to be assessed with a focus on its impact on pupils’ learning. The conflict between\nwinter thermal comfort and natural ventilation has been investigated in a number of studies and,\nwhile it is understood that the risk of poor IAQ in the classroom is higher in winter, more often than\nnot there is not enough evidence to support a correlation between indoor temperatures and IAQ.\nThis study uses monitoring data to investigate if classrooms in a naturally ventilated and poorly\ninsulated building are more prone to a negative correlation between mean outdoor temperature and\nindoor CO2 levels, compared to a naturally ventilated super-insulated and a Passivhaus building.\nFindings from this study, suggested that in order to eliminate the risk of a negative effect on children’s\nhealth and performance due to poor IAQ in colder climates, we need to invest in well-insulated\nairtight Passivhaus schools equipped with mechanical ventilation with heat recovery, and CO2 dictated\nsupply rates. Further research shall use thermal dynamic simulation and CFD analysis for classrooms\nin different building types in the UK, to reveal the ideal strategy and design.
Cod (Gadus morhua) rearing attempts in France

Field: Agricultural and Biological Sciences (Life Sciences)

Because of its rapid growth, its good reputation and the promising aquaculture experiences conducted in Norway and Scotland, cod is considered as a good candidate for cold water aquaculture. The aim of this paper is to present the work carried out in France since 1999: the selection of cod as a promising candidate for aquaculture and the assessment of its rearing performances in this environment.
Rupture of the Posterior Tibia1 Tendon Associated with Closed Ankle Fracture

Field: Medicine (Health Sciences)

Rupture of the posterior tibial tendon has rarely been associated with closed ankle fractures. All previous cases have been in association with pronation-external rotation type fractures in which the medial malleolus has been fractured. This case represents the first such report of a severed posterior tibial tendon in the absence of a medial malleolar fracture and reemphasizes the importance of critically evaluating intraoperative radiographs following the open reduction and internal fixation of closed ankle fractures to assess the possibility of soft tissue interpo-sition. In the event of an acute rupture of the posterior tibial tendon, the authors recommend primary tendon re-pair.
Recovering class diagrams from data-intensive legacy systems

Field: Computer Science (Physical Sciences)

Several reverse engineering methods for recovering objects from legacy systems have been proposed in the literature, but most of them neglect to identify the relationships among the objects, or recover only a part of them. The paper describes a method for recovering an OO (object oriented) model together with the objects and relationships among them. The proposed approach integrates the results of reverse engineering of both the procedural code and the persistent data stores of the system, and exploits a number of heuristic criteria to obtain a class diagram. A preliminary experiment carried out to validate the method on a COBOL medium-sized system yielded encouraging results.
Femtosecond Laser Assisted Keratoplasty

Field: Medicine (Health Sciences)

Femtosecond lasers have a wide variety of applications in anterior segment surgery. The technology has also been used for lamellar and penetrating keratoplasties. Graft-host misalignment frequently occurs with conventional penetrating keratoplasty that leads to significant post-operative astigmatism. Improved wound designs with the femtosecond laser-mushroom, top-hat, zig-zag, Christmas tree, and dovetail, increase the surface area of apposition and provide more secure incisions. Early visual rehabilitation and suture removal are possible advantages. Lesser post-operative astigmatism has also been reported. Deep anterior lamellar keratoplasty with the femtosecond laser (FDALK) may help reduce intra-operative complications like perforation of the Descemet's membrane. Incision designs similar to penetrating grafts are used. Femtosecond laser assisted anterior lamellar keratoplasty (FALK) is useful for superficial corneal scars and dystrophies. Sutureless replacement of the anterior corneal stroma greatly enhances visual rehabilitation and limits induced post-operative astigmatism. Additional procedures like photo-refractive keratectomy (PRK) may be performed for refractive errors, post-operatively. Femtosecond laser assisted endothelial keratoplasty (FLEK) has been used to cut donor discs. However, deep in the corneal stroma, microkeratomes give smoother cuts. Disadvantages with this technology include increased cost, longer operative time, and logistics. However, the precision and accuracy of the femtosecond laser has the potential to overcome many of the problems faced with conventional corneal transplant procedures.