jimnoneill/paper-to-field-training huggingface dataset:
The correlation between vascular endothelial growth factor and prostate cancer with and without metabolic syndrome

Field: Medicine (Health Sciences)

Objective: To investigate the relationship between vascular endothelial growth factor (VEGF), metabolic syndrome and its components and degree of differentiation of prostate cancer. Methods: The clinical data of 49 PCa cases treated during October, 2018 to February, 2021 were retrospectively analyzed, including patients’ height, weight, body mass index (BMI), age, blood pressure (BP), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG), vascular endothelial growth factor (VEGF) and Gleason score. Results: Compared with simple PCa group, BMI, the MS group had higher BMI, diastolic blood pressure (DBP, FGB, TG) and VEGF (P<0.05), and higher Gleason score (P<0.05). MS group had a higher degree of malignancy (Gleason≥8). Conclusion: This suggests that MS may promote the progression of PCa, and the increase of VEGF level can indicate the presence of MS in PCa patients, reflecting the progression of PCa to a certain extent.
Developing of Conceptual Change Text (CCTs) based on conceptual change model to increase students’ conceptual understanding and remediate misconception in kinematics

Field: Social Sciences (Social Sciences)

The main objectives of this research are to develop a valid and practical Conceptual Change Texts (CCTs) material related to Newtonian Mechanics and to test the influence of the CCTs in order to increase students’ conceptual understanding and overcome their misconceptions in the relevant topics. The research is divided in to two years comprising of three steps, namely 1) preliminary study, 2) design development, and 3) product testing. This article reports some result of the first year research for kinematics materials. The method for the first and the second steps are descriptive qualitative and development research, respectively. Based on the analysis of the preliminary data it is found the weakness of the basic and standard competencies for Newtonian Mechanics materials in Basic Physics 1 course and it has been changed from 7 to 9 standard competencies. It was also arranged essential material and found 9 common misconceptions in kinematics, namely velocity and acceleration are considered equal, position and velocity are considered equal, velocity is not as vector quantity, ego-centered reference frame, heavier objects fall faster, gravity increase as an object falls, acceleration differs along the trajectory of a projectile motion, an object thrown vertically upward from a linier moving object will land behind this moving object, and a bullet will not hit a target if the target falls down at the same time the bullet is fired. These findings are basis to develop the CCTs. It is developing the CCTs for kinematics comprises of: case, question(s), space to answer and reason, kinds of misconceptions, and explanation of the right concepts. The CCTs in turn can be utilized to improve learners’ conceptual understandings and to remediate their misconceptions toward the truer concepts in the Kinematics topics. \n
INDEPENDENT MARGINALS OF OPERATOR LEVY’S PROBABILITY MEASURES ON FINITE DIMENSIONAL VECTOR SPACES

Field: Mathematics (Physical Sciences)

Abstract. We find exponents of independent marginals of operator Lévy’s measures, and show that those measures which are convolutions of one-dimensional factors are multivariate Lévy’s with the factors being Lévy’s too. A characterization of exponents of such measures is also given. Introduction. In this note we shall be concerned with independent marginals of operator Lévy’s measures on finite dimensional vector spaces. For the operator-stable and operator-semistable measures, problems of this type have been studied in [1, 2, 4, 7]; it is shown there that the existence of a complete set of independent pairwise orthogonal univariate marginals
Radial Velocities of Twenty Stars of Early Type in and Near the Galactic Cluster NGC 6231.

Field: Physics and Astronomy (Physical Sciences)

view Abstract Citations (74) References Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Radial Velocities of Twenty Stars of Early Type in and Near the Galactic Cluster NGC 6231. Struve, O. Abstract The radial velocities of 16 normal stars of types c09-cB2 have been derived, together with those of 2 WoIf-Rayet stars and 2 P Cygni type stars. All 20 stars belong to one physical group. The emission lines of the WN7 star show appreciable red shifts of different amounts. The phenomenon is correlated with the intensities of the violet absorption lines. The violet absorptions of certain lines change in intensity, and there may also be structural changes in the emission lines. The radial velocity was constant. The WC6 star shows central absorptions in some of the emission lines which are shifted toward the violet. These central absorptions and the centers of the emission bands show large, but uncorrelated, shifts over inter- vals of several days. The 2 P Cygni type stars show pronounced red shifts for those emission lines which are accompanied by violet absorption borders Publication: The Astrophysical Journal Pub Date: September 1944 DOI: 10.1086/144657 Bibcode: 1944ApJ...100..189S full text sources ADS | data products SIMBAD (21)
Synthesis, Spectroscopic Analysis, and in Vitro/in Silico Biological Studies of Novel Piperidine Derivatives Heterocyclic Schiff‐Mannich Base Compounds

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Abstract In the present study, 3‐substitued‐4‐(4‐hydroxybenzylidenamino)‐4,5‐dihydro‐1 H ‐1,2,4‐triazol‐5‐ones ( S1‐8 ) were synthesized by treating 4‐hydroxybenzaldehyde ( B ) with eight different 3‐substitued‐4‐amino‐4,5‐dihydro‐1 H ‐1,2,4‐triazole‐5‐ones ( T1‐8 ) in acetic acid medium, separately. The synthesized Schiff bases ( S ) were reacted with formaldehyde and secondary amine such as 4‐piperidinecarboxyamide to afford novel heterocyclic bases. 3‐Substitued‐4‐(4‐hydroxybenzylidenamino)‐4,5‐dihydro‐1 H ‐1,2,4‐triazol‐5‐ones ( T ) were treated with 4‐piperidinecarboxyamide in the presence of formaldehyde to synthesize eight new 1‐(4‐piperidinecarboxyamide‐1‐yl ‐ methyl)‐3‐substitued‐4‐(4‐hydroxybenzylidenamino)‐4,5‐dihydro‐1 H ‐1,2,4‐triazol‐5‐ones ( M1‐8 ). The structure characterization of compounds was carried out using 1 H‐NMR, IR, HR‐MS, and 13 C‐NMR spectroscopic methods. The inhibitory properties of the newly synthesized compounds were calculated against the acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and glutathione S‐transferase (GST) enzymes. Ki values were calculated in the range of 20.06±3.11–36.86±6.17 μM for GST, 17.87±2.91–30.53±4.25 μM for AChE, 9.08±0.69–20.02±2.88 μM for BChE, respectively, Besides, IC 50 values were also calculated. Best binding scores of ‐inhibitors against used enzymes were calculated as −12.095 kcal/mol, −12.775 kcal/mol, and −9.336 kcal/mol, respectively. While 5‐oxo‐triazole piperidine‐4‐carboxamide moieties have a critical role in the inhibition of AChE and GST enzymes, hydroxy benzyl moiety is important for BChE enzyme inhibition.
The Fundamentalist Mentality: Its Philosophical Roots

Field: Arts and Humanities (Social Sciences)

Abstract This chapter discusses the philosophical ideas and movements that inspired the Fundamentalist mentality. According to James Barr, the prevalence of rationalism is one of the key features that render the present Conservative Evangelicalism as Fundamentalists. He cites the pre-Kantian empirical rationalism as popularized by theologians Charles Hodge and Benjamin Warfield as the main philosophical root of the current Fundamentalist thinking.
ORTHODOX MONASTIC EXPERIENCE AND HERMITIC PRACTICE IN THE POLISH-LITHUANIAN COMMONWEALTH

Field: Arts and Humanities (Social Sciences)

This paper is dedicated to a famous Ukrainian monastic saint – Jov Knjahynyc’kij (ca. 1550–1621), a founder of Manjava Skete (also known as the Great Skete) in the Carpathian Mountains, an Orthodox monk, who spent a big part of his life en route between the Polish-Lithuanian Commonwealth, Mount Athos, Moldavia, and Muscovy. His itinerary can be reconstructed on the basis of his Vita, which was composed probably soon after his death. Its author is known as hieromonk Ignatij from Ljubarov. Vita was published in 1860 by Anthony Petrushevych (1821–1913), a Ukrainian historian and linguist. It was also Petrushevych, who edited the most important sources for the early history of the Manjava Skete – the Spiritual Testament by Theodosius as well as the monastic rule of the skete. Already the first monograph on the history of Manjava Skete, from its establishment in 1611 until its closure in 1785 by Julian Celevič (1843–1892), was based on Petrushevych’s editions. The translation of Jov’s Vita and of the spiritual testament of Theodosius into English was prepared in a critical edition with commentaries by Sophia Senyk.
An e-mail honeypot addressing spammers' behavior in collecting and applying addresses

Field: Computer Science (Physical Sciences)

Spam has become one of the most annoying and costly phenomenon in the Internet. Valid e-mail addresses belong to the most valuable resources of spammers, but little is known about spammers’ behavior when collecting and harvesting addresses and spammers’ capabilities and interest in carefully directed, consumer-oriented marketing have not been explored yet. Gaining insight into spammers’ ways to obtain and (mis)use e-mail addresses is useful in many ways, e.g. for the assessment of the effectiveness of address obscuring techniques and the usability and necessity of hiding e-mail addresses on the Internet. This paper presents a spam honeypot project in progress addressing these issues by systematically placing e-mail addresses in the Internet and analyzing received e-mails. The honeypot’s conceptual framework, its implementation, and first empirical results are presented. Finally, an outlook on further work and activities is provided.
Scleral topography and its usefulness in scleral lens fitting

Field: Health Professions (Health Sciences)

Background: Scleral lenses are one of the best options to manage corneal irregularities and severe ocular surface diseases. As scleral lenses rest on the sclera, scleral topographical data are necessary when fitting these lenses. Aim: The aim of this article was to present a review of the literature on scleral topography and its usefulness in scleral lens fitting. Method: A search was performed by the author with the PubMed database for the literature related to the topic by using a combination of keywords as search criteria. The most specific combination was represented by the junction of keywords (scleral topography and scleral lens fitting). Forty-four articles were related to scleral topography and scleral lens fitting. Results: Fifteen articles were found to be more relevant to the topic and were selected for review. These articles originated from 11 different countries and five continents. Many (60%) of the articles were from European countries. Conclusion: The shape of the anterior surface of the eye beyond the limbus is not rotationally symmetrical, and the asymmetry increases as we move away from the limbus. Scleral topography is important in the fitting of scleral lenses, especially that keratometry measurements cannot be used to predict the base curve of the best fitting scleral lens.
The Post-national Constellation of Industrial Relations Systems in the European Legal Order

Field: Social Sciences (Social Sciences)

This paper develops a new interpretation of the norms of the Treaty of Lisbon to find the juridical basis for an autonomous system of European industrial relations. In particular, the study explores the question of whether the provisions in EU law (art. 152, 154 and 155 TFEU and art 28 Charter FSR) could constitute a sufficient basis for granting social parties the power to regulate sectors under their competence (such as social policy) through collective bargaining, without the involvement of European institutions. In so doing, the author advances the hypothesis of an extra-institutional system of rule-making, the efficacy of which is measurable over time, depending on the agreement’s degree of propagation, outside of the dual-logic hermeneutic approach (binding vs. non binding). Despite the as yet only embryonic capacity of trade unions to coordinate among themselves, the author gives some examples of the autonomous development of European collective bargaining to support the hypothesis, looking also at the transnational level. In the light of the theoretical framework and autonomous negotiations, the author argues that there is a new mode of normative regulation, made by social partners and aimed at achieving social policy objectives.
Does Mentoring Matter in the Mental Health Field?

Field: Health Professions (Health Sciences)

This study explores the presence of mentoring relationships among a sample of 56 mental health professionals in a large county mental health agency. Participants completed the Alleman Mentoring Scales Questionnaire in an online survey. Individuals involved in mentoring relationships experienced more career and psychological enhancing functions in the work place than those who were not in mentoring relationships. Mentoring relationships predicted career and personal development of mental health professionals. Recommendations include incorporating mentoring programs in mental health agencies in order to increase social workers' competence in their jobs.
[Trophoblastic beta 1-glycoprotein in the blood in trophoblastic tumors].

Field: Medicine (Health Sciences)

Trophoblastic beta 1-glycoprotein (TBG) or a "specific protein of pregnancy" isolated from placental extracts and retroplacental serum, is a reliable marker of trophoblastic tumors. A highly sensitive quantitative radioimmunoassay to determine TBG was developed. The use of this method in the Department of Gynecology. All-Union Cancer Research Center, USSR AMS, for a dynamic observation over patients with different trophoblastic tumors for 3 yrs. has shown that TBG is determined in 94.7% of the cases, this antigen concentration correlating with the disease stage and reflecting a clinical course of the disease. Chorionic gonadotropin (CG) determined simultaneously in the urine of the same patients, was found in 84% of the cases. TBG indices correlate with the CG level in 75% of the cases and serve as an important criterion in the diagnosis and evaluation of efficacy of treatment provided to patients with trophoblastic tumors.
Possible Roles of Amyloids in Malaria Pathophysiology

Field: Medicine (Health Sciences)

The main therapeutic and prophylactic tools against malaria have been locked for more than a century in the classical approaches of using drugs targeting metabolic processes of the causing agent, the protist Plasmodium spp., and of designing vaccines against chosen antigens found on the parasite's surface. Given the extraordinary resources exhibited by Plasmodium to escape these traditional strategies, which have not been able to free humankind from the scourge of malaria despite much effort invested in them, new concepts have to be explored in order to advance toward eradication of the disease. In this context, amyloid-forming proteins and peptides found in the proteome of the pathogen should perhaps cease being regarded as mere anomalous molecules. Their likely functionality in the pathophysiology of Plasmodium calls for attention being paid to them as a possible Achilles' heel of malaria. Here we will give an overview of Plasmodium-encoded amyloid-forming polypeptides as potential therapeutic targets and toxic elements, particularly in relation to cerebral malaria and the blood-brain barrier function. We will also discuss the recent finding that the genome of the parasite contains an astonishingly high proportion of prionogenic domains.
Economic and spatial strategies of artists as cultural entrepreneurs

Field: Economics, Econometrics and Finance (Social Sciences)

Abstract The text aims to explore the economic and spatial strategies followed by artists who run micro-firms. The authors analyse results of a qualitative study of independent artist enterprises in Kraków. It reveals that motivations for artistic entrepreneurship are diverse and foremost linked with the need to overcome challenges artists experience in the labour market and in the market for cultural goods and services. Different strategies translate into particular location choices as well as varied visibility of such firms in urban space.
Characterization of purified His-tagged CP47-containing photosystem II complexes from a cyanobacterium, Synechocystis sp. PCC 6803

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

For the determination of the exact structure of PS II complexes, all the polypeptide constituents must be identified. For this purpose, highly active photosystem II (PS II) complexes were purified from a HT-3 mutant of Synechocystis sp. PCC 6803 whose CP47 has been His-tagged. Fluorescence measurements showed the intactness of the donor and acceptor sides of purified PS II complexes. It retained 80% of the initial activity of oxygen evolution even after incubation of the complexes for 2 weeks at 4°C in the dark. Using these highly purified PS II complexes, the polypeptide composition was analyzed by SDS-PAGE which can resolve polypeptides of low molecular weight. Separated polypeptides of the purified PS II complexes were subjected to N-terminal amino acid sequencing and matrix assisted laser desorption (MALDI) mass spectrometry. More than 20 Coomassie-stainable polypeptides were identified. All the polypeptides which was known as PS II components were found, except PsbN. Besides 19 polypeptides of well-known PS II member, some polypeptides, which had not been shown to bind to PS II complexes until now, were found. Among such polypeptides, the sll1638 gene product was found to be highly homologous to PsbQ. These PS II complexes contained the FtsH protein, which was assigned to be a protease of the D1 protein, and the Ycf9 (Orf62 in tobacco), which was suggested to be present in stromal thylakoids. The results obtained here showed the usefulness of this HT-3 strain for the investigation of the structure, function and biogenesis of PS II complexes.
Development and Characterization of Gefitinib Loaded Polymeric Nanoparticles by Ionic Gelation Method

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The nanoparticle formulation with desired characteristics can be prepared at low concentration of chitosan and STPP along with low volume of STPP. The formulated nanoparticles may prove to be the best option for the treatment of cancer.
Carbon tetrachloride and croton oil in treatment of hookworm infections

Field: Medicine (Health Sciences)

Carbon tetrachloride and croton oil in treatment of hookworm infections W.M. Strong W.M. Strong Chief Medical Officer, Papua Search for other works by this author on: Oxford Academic PubMed Google Scholar Transactions of The Royal Society of Tropical Medicine and Hygiene, Volume 20, Issue 1-2, 20 May 1926, Page 132, https://doi.org/10.1016/S0035-9203(26)80025-2 Published: 20 May 1926
The Determinants of Firm Access to Credit in Latin America: Micro Characteristics and Market Structure

Field: Economics, Econometrics and Finance (Social Sciences)

Due to deregulation and financial liberalization, Latin American countries have recently undertaken bank restructuring and consolidation processes. This paper investigates firm access to credit in the region, focusing on the role of the credit market structure. Through an empirical investigation based on the World Bank Enterprise Survey, we find that access to bank credit is very heterogeneous. On average, smaller and less productive firms are less likely to apply for credit and more likely to be financially constrained. Besides, a high degree of bank penetration and competition is significantly correlated with a lower probability that borrowers are financially constrained. Finally, foreign banks penetration has a negative effect on access to credit particularly in less developed and more concentrated markets, while it has a positive influence in more competitive and financially developed markets.
A comparison of biological effect and spray liquid distribution and deposition for different spray application techniques in different crops

Field: Agricultural and Biological Sciences (Life Sciences)

The objective of this study was to compare a selection of spray application techniques with different application volumes, with respect to the spray liquid distribution on flat surfaces, the deposition in fully developed crops and the biological effect. The spray application techniques in this study were conventional spray technique with three different nozzles: Teelet XR, Lechler ID and Lurmark DriftBeta, and also AirTec, Danfoil, Hardi Twin, Kyndestoit and Släpduk. The dynamic spray liquid distribution was measured on a flat surface, spraying a water and black dye solution on pre-glued wallpaper lengths. Spraying the same dye-water solution in established crops, the spray deposition on plant and on the ground was studied by measuring the absorbance of sampled leafs' and collectors' rinsing water. Spray deposition studies were made in winter wheat and potato. The biological effect was studied in field experiments with plots with linearly increased dose. The field trials in this study were weed control in spring barley, fungi control in winter wheat and potato late blight control. The weed weight was sampled and visual assessments were made of the infection of fungi. Grain yield and 1000-kernel-weight were sampled in the wheat trial. The dynamic spray liquid distribution resulted in coefficients of variation, for all spray techniques, between 5% and 16%, which were considered to be at acceptable levels. Relatively large significant differences were found in the spray deposition measurements in potato canopies. For conventional spray technique, 90% spray deposition was recovered in the top of the canopy. Higher deposition was recovered in the lower part of the canopy and on the ground for Danfoil, Hardi Twin and Släpduk than the other techniques. In the wheat crop, the differences in spray deposition between spray techniques were smaller. Släpduk had the greatest increase in liquid deposition on the head and the flag leaf. The techniques with external air assistance, Hardi Twin and Kyndestoft, had the lowest deposition on the ground. Analysing the effect of weed control in spring barley, fungi control in wheat and potato late blight control, no significant differences were found. This might be seemed remarkable when large differences in spray liquid deposition were found in the potato canopy. One conclusion could be that the penetration ability in dense potato canopies is not of equal importance as to protect the upper parts of the canopy. It is indicated that it could be important to consider other factors, not included in this study, such as the ability to reduce drift and increase capacity, when selecting spray application technique
ACCURACY STUDY ON THE REGISTRATION OF THE TIBIA BY MEANS OF AN INTRAMEDULLARY ROD IN ROBOT- ASSISTED TOTAL KNEE ARTHROPLASTY

Field: Medicine (Health Sciences)

Group α (°) s(°) α (°) s(°) α (°) s(°) 3D 1.36 0.94 2.16 1.35 2.85 1.19 F 0.51 0.99 0.51 0.99 -0.10 1.24 1 S -0.14 1.30 1.67 1.66 -1.60 2.51 3D 1.69 0.97 2.60 1.27 1.88 0.78 F 0.21 1.12 0.21 1.12 -0.87 0.69 2