jimnoneill/paper-to-field-training huggingface dataset:
Shakespeare dancing: a theatrical study of the plays

Field: Arts and Humanities (Social Sciences)

shakespeare dancing a theatrical study of the plays is available in our digital library an online access to it is set as public so you can download it instantly. Our digital library spans in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Kindly say, the shakespeare dancing a theatrical study of the plays is universally compatible with any devices to read.
Topological Conjugacy Between Seizure and Flat Electroencephalography

Field: Neuroscience (Life Sciences)

Problem statement: Seizure and Flat EEG which are modeled as two distinct dynamical systems share the same dynamics in the topological viewpoint. Approach: Motions of seizure and Flat EEG of the dynamical systems were written as set points. A function that maps between these two sets is then built. By using topological conjugacy, they are shown to share the same dynamics. Results: Seizure and Flat EEG were shown to share the same dynamics along with other properties such as order isomorphic, homeomorphic and the unique representation of any event during seizure as an open set. Conclusion: This study shows that the dynamics of seizure can be transported to Flat EEG.
Comparison of TKI and CPI strategies as first-line treatment of patients with advanced renal cell carcinoma: Real-world outcome data from the German research platform CARAT.

Field: Medicine (Health Sciences)

4528 Background: Immune checkpoint inhibitors (CPI), in combination with tyrosine kinase inhibitors (TKI) or with another CPI, expanded the therapeutic options for advanced or metastatic renal cell carcinoma (mRCC) beyond TKI-Monotherapy. However, no head-to-head clinical trials comparing 1 st -line (1L) CPI+CPI vs. TKI+CPI have been performed. Here, we analyzed outcome of non-randomized patients (pts) treated 1L with one of the three strategies in routine care. Methods: CARAT (NCT03374267) is an ongoing, prospective, observational, longitudinal, multicenter clinical registry for mRCC pts in Germany. Details on (sequential) treatments, patient and tumor characteristics and clinical and patient-reported outcomes are collected. Follow-up is until death or up to 3 years. By January 2024, almost 1100 pts had been enrolled by 148 sites. Pts with start of 1L treatment after 15/01/2019 were analyzed (data cut 06/30/2023). PFS and OS were estimated using the Kaplan-Meier method. Inverse probability of treatment weighting (IPTW) by propensity score analysis was used to compare PFS (primary endpoint) and OS (secondary endpoint) between 1L TKI or CPI+CPI or TKI+CPI. IPTW was performed for the following variables: age, sex, IMDC risk groups, histology, any comorbidity, Charlson comorbidity index, metastatic stage, type of metastasis and number of metastatic sites. After IPTW, the three treatment groups were comparable for the variables listed above. Results: From 2019 until data cut for this analysis, 991 pts were investigated, thereof 418 pts (42%) received TKI+CPI, 242 pts (24%) CPI+CPI and 263 pts (27%) received TKI monotherapy as 1L. 51/61/80% of pts had a progression or death after 1L (TKI+CPI/CPI+CPI/TKI strategy group). IPTW-adjusted median PFS was 12.7 months (95% confidence interval (CI) [10.4 – 15.6]) for TKI+CPI, 8.0 [6.3 – 10.9] months for CPI+CPI and 9.7 [7.4 – 12.0] months for TKI. Hazard ratio (HR) was 1.24 (0.97 – 1.58) for CPI+CPI versus TKI+CPI and 1.33 (1.09 – 1.61) for TKI versus TKI+CPI. 30/42/51% of pts had died (TKI+CPI/CPI+CPI/TKI strategy group). IPTW-adjusted median OS was 31.5 [26.4 – NA] months for TKI+CPI, 22.3 [17.1 – 37.5] months for CPI+CPI and 31.4 [22.8 – 37.1] months for TKI. HR was 1.30 (0.98 – 1.73) for CPI+CPI versus TKI+CPI and 1.08 (0.83 – 1.41) for TKI versus TKI+CPI. Subgroup analyses by IMDC score as well as data on quality of life and on subsequent line treatments will also be presented. Conclusions: IPWT-adjusted outcome analysis of real-world data in the CARAT registry did not detect significant differences in PFS and OS between pts treated with 1L TKI+CPI compared to CPI+CPI when adjusted for a wide range of potential confounding variables. Further analyses in other cohorts are warranted to confirm these findings.
PENGARUH DEFAULT RISK, RISIKO SISTEMATIS, PROFITABILITAS,DAN PENGUNGKAPAN CORPORATE SOCIAL RESPONSIBILITY TERHADAP EARNINGS RESPONSE COEFFICIENT (ERC)

Field: Economics, Econometrics and Finance (Social Sciences)

PENGARUH DEFAULT RISK, RISIKO SISTEMATIS, PROFITABILITAS,
DAN PENGUNGKAPAN CORPORATE SOCIAL RESPONSIBILITY TERHADAP EARNINGS RESPONSE COEFFICIENT (ERC)

ABSTRAK

Penelitian ini bertujuan untuk membuktikan secara empiris pengaruh Default Risk,
Risiko Sistematis, Profitabilitas dan Pengungkapan Corporate Social Responsibility
Terhadap Earnings Response Coefficient (ERC). Variabel independen dalam
penelitian ini yaitu Default Risk, Risiko Sistematis, Profitabilitas dan Pengungkapan
Corporate Social Responsibility, variabel dependennya yaitu Earnings Response
Coefficient (ERC). Sampel penelitian ini adalah perusahaan pertambangan yang
terdaftar di BEI. Penelitian ini menggunakan purposive sampling. Pengumpulan data
dilakukan dengan metode pengumpulan data yang diperoleh dari laporan keuangan
perbankan yang didapat dari website idx.com. Berdasarkan hasil analisis
menunjukkan bahwa Risiko Sistematis berpengaruh terhadap Earnings Response
Coefficient (ERC), sedangkan Default Risk, Profitabilitas dan Pengungkapan
Corporate Social Responsibility tidak berpengaruh terhadap Earnings Response
Coefficient (ERC)..
Kata kunci : Earnings Response Coefficient (ERC), Default Risk, Risiko Sistematis, Profitabilitas, dan Pengungkapan Corporate Social Responsibility.
Role of Caveolar Compartmentation in Endothelium-Derived Hyperpolarizing Factor–Mediated Relaxation

Field: Medicine (Health Sciences)

Background— In endothelial cells, caveolin-1, the structural protein of caveolae, acts as a scaffolding protein to cluster lipids and signaling molecules within caveolae and, in some instances, regulates the activity of proteins targeted to caveolae. Specifically, different putative mediators of the endothelium-derived hyperpolarizing factor (EDHF)–mediated relaxation are located in caveolae and/or regulated by the structural protein caveolin-1, such as potassium channels, calcium regulatory proteins, and connexin 43, a molecular component of gap junctions. Methods and Results— Comparing relaxation in vessels from caveolin-1 knockout mice and their wild-type littermates, we observed a complete absence of EDHF-mediated vasodilation in isolated mesenteric arteries from caveolin-1 knockout mice. The absence of caveolin-1 is associated with an impairment of calcium homeostasis in endothelial cells, notably, a decreased activity of Ca 2+ -permeable TRPV4 cation channels that participate in nitric oxide– and EDHF-mediated relaxation. Moreover, morphological characterization of caveolin-1 knockout and wild-type arteries showed fewer gap junctions in vessels from knockout animals associated with a lower expression of connexins 37, 40, and 43 and altered myoendothelial communication. Finally, we showed that TRPV4 channels and connexins colocalize with caveolin-1 in the caveolar compartment of the plasma membrane. Conclusions— We demonstrated that expression of caveolin-1 is required for EDHF-related relaxation by modulating membrane location and activity of TRPV4 channels and connexins, which are both implicated at different steps in the EDHF-signaling pathway.
Effect of Zn, Fe and FYM on Interaction between Zn and Fe on Nutrient Content, Uptake and Yield of Different Varieties of Rice (Oryza sativa L.)

Field: Agricultural and Biological Sciences (Life Sciences)

The field experiment were carried out using split plot design with three replication during kharif 2006-07 and 2007-08 to investigate the effect of varieties and Zn, Fe and FYM on nutrient content, uptake and yield of rice (Oryza sativa). The experiment consisted of two level of varieties (V1:NDR-359, V2:HUBR-2-1) and two fertilizer source (F1:RFD100, F2:RFD75+FYM25) in main plot and nine level of micronutrient combination (M0:0, M1:Zn-EDTA1, M2:Zn-EDTA0.5, M3:Fe-EDTA1, M4:Fe-EDTA0.5, M5:Zn-EDTA1+Fe-EDTA1, M6:Zn-EDTA0.5+Fe-EDTA0.5, M7:Zn-EDTA1+Fe-EDTA0.5, M8:Fe-EDTA1+Zn-EDTA0.5) allotted in sub-plot. Among the different testing varieties, V1:(NDR-359) recorded highest yield and NPK content in grain, while significant content of Zn and Fe recorded in HUBR-2-1. Among different fertilizer sources, nutrient supplied through RFD75+FYM25 was record improvement in Zn and Fe content and uptake in grain and straw of rice. The significantly high content of Zn and their uptake in grain recorded under supply through the micronutrient level M7 (Zn:EDTA1+Fe-EDTA0.5). Whereas foliar application of M4:Fe-EDTA0.5 at 15 DAT and 50% panicle initiation significantly increased Fe content and uptake in grain and straw. Interaction effect of HUBR-2-1 and RFD75+FYM25 with single application of Zn-EDTA1 through soil recorded significant zinc content in grain. It can be concluded that the NDR-359 was found the high yielding rice cultivar responding to RFD75+FYM25 along with supply of micronutrient as Zn-EDTA1+Fe-EDTA0.5 in alluvial soil of Uttar Pradesh.
Long-term self-administered subcutaneous heparin in pregnancy.

Field: Computer Science (Physical Sciences)

An Intelligent Playground is an environment with interactive objects that, using advanced technology such as sensors and actuators, react to the interaction with the children and actively encourage children to play. Thus, an intelligent playground stimulates children to move and play together. In this way, it provides for a healthy alternative for popular pastimes such as computer games and television.\nWe propose a design research agenda for Intelligent Playgrounds, identifying key issues regarding the design of these playgrounds: social interaction, simplicity, challenge, goals and feedback. We illustrate these issues by referring extensively to related work in this area. In addition, we present our design approach, initial findings and future plans on the basis of two case studies of new intelligent playground concepts.
Agriculture, Manufacturing and Economic Growth in India: A Co-integration Analysis

Field: Economics, Econometrics and Finance (Social Sciences)

This study examine the most debatable question of the last three decade, i.e., “Does the agriculture affect the economic growth?” with the use of annually data from 1966-to 2016. The study employed unit root and causality test suggested by the Dicky fuller, Phillips-Perron and Granger respectively. Besides, ARDL techniques used to analysis the relationship among the variables, i.e., agriculture, manufacturing and economic for the short as well as long period of time. As per outcome, result shows that, uni-directional causality running from manufacturing and economic to agricultural growth. Moreover, unidirectional causality running from economic to manufacturing growth. Results also showed that bidirectional causal relationship between economic and agriculture growth. It can be concluded that, this study support of a very famous statement “agriculture is the engine of economic growth this statement is valid for the short period of time but manufacturing contributed more than agriculture sector to the economic in the long run in India.
Problems of epidemiology, therapy and laboratory diagnostics of infectious diseases — 2024: Abstract book of the Scientific and practical conference of young scientists and specialists of the Central Research Institute of Epidemiology of Rospotrebnadzor

Field: Medicine (Health Sciences)

The collection of conference abstracts includes works devoted to the epidemiology and clinical picture of infectious diseases, modern issues of laboratory diagnostics, bioinformatics, molecular diagnostics, genomic epidemiological surveillance and the potential of big data analysis for understanding epidemiological processes. Abstracts emphasize an interdisciplinary approach, bringing together young scientists from various fields of science to discuss and solve complex problems. The collection represents an important step in supporting young scientists by providing them with the opportunity to publish their research and share their experiences with colleagues, promoting their professional growth and contributing to global health, highlighting the importance of scientific research for society. The materials are intended for laboratory diagnostic specialists, epidemiologists, microbiologists, hygienists, clinical specialists, employees of research institutions, students, residents and graduate students of respective specialties.
Synthesis and biological evaluation of thieno[3,2-c]pyrazol-3-amine derivatives as potent glycogen synthase kinase 3β inhibitors for Alzheimer’s disease

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Glycogen synthase kinase 3β (GSK-3β) catalyses the hyperphosphorylation of tau protein in the Alzheimer’s disease (AD) pathology. A series of novel thieno[3,2-c]pyrazol-3-amine derivatives were designed and synthesised and evaluated as potential GSK-3β inhibitors by structure-guided drug rational design approach. The thieno[3,2-c]pyrazol-3-amine derivative 16b was identified as a potent GSK-3β inhibitor with an IC50 of 3.1 nM in vitro and showed accepted kinase selectivity. In cell levels, 16b showed no toxicity on the viability of SH-SY5Y cells at the concentration up to 50 μM and targeted GSK-3β with the increased phosphorylated GSK-3β at Ser9. Western blot analysis indicated that 16b decreased the phosphorylated tau at Ser396 in a dose-dependent way. Moreover, 16b effectively increased expressions of β-catenin as well as the GAP43, N-myc, and MAP-2, and promoted the differentiated neuronal neurite outgrowth. Therefore, the thieno[3,2-c]pyrazol-3-amine derivative 16b could serve as a promising GSK-3β inhibitor for the treatment of AD.
Occurrence Download

Field: Agricultural and Biological Sciences (Life Sciences)

A dataset containing 67 species occurrences available in GBIF matching the query: { "TaxonKey" : [ "is Crassula brevifolia subsp. brevifolia" ] } The dataset includes 67 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0128032-200613084148143/datasets/export for details. Data from some individual datasets included in this download may be licensed under less restrictive terms.
Chapter 7: Intravenous Flow Rates

Field: Health Professions (Health Sciences)

PreviousNext No AccessComplete Math Review for the Pharmacy Technician, 4th EditionChapter 7: Intravenous Flow Rateshttps://doi.org/10.21019/9781582121970.ch7 SectionsAboutFull Text ToolsAdd to favoritesDownload CitationsTrack Citations ShareFacebookTwitterLinkedInRedditEmail PreviousNext Session Activity Recently Viewed Chapter 7: Intravenous Flow Rates William A. Hopkins Recently Searched No search history FiguresReferencesRelatedDetails Published: 23 November 2016eISBN: 1-58212-197-4 Copyright & Permissions© 2014 by the American Pharmacists Association. All rights reserved.© 2014 by the American Pharmacists Association. All rights reserved. Publisher American Pharmacists Association HistoryPublished: 23 November 2016 Citation Information (2014), "Chapter 7: Intravenous Flow Rates," Complete Math Review for the Pharmacy Technician, 4th Edition https://doi.org/10.21019/9781582121970.ch7 Loading ...
Breast Magnetic Resonance Imaging (MRI) – expectations versus possibilities. Problem concerning clinician–radiographer, and radiographer–radiographer communication

Field: Health Professions (Health Sciences)

As the number of MRI laboratories equipped with resonance systems featuring magnetic field strengths of more than one Tesla as well as coils dedicated to breast examinations increases, such examinations are being made at increasing frequency. Clinicians expect the summaries to include exhaustive information concerning the topography of detected lesions as well as approximate staging of the disease process, which helps them in making decisions regarding further management. On the other hand, radiographers performing medical check-ups, expect the previous examination summary to include a wide range of information facilitating comparative analysis and evaluation of scan efficacy. Undoubtedly, breast MR offers an opportunity to obtain aforementioned information. However, the indispensable requirement for preparation of such summary is radiographer's awareness of the expectations being raised. We have to face the difficult task of standardizing the summaries, and even more than that, of making our colleagues aware of the importance of each sentence included in or excluded from the summary. This article is an attempt to present the correct form of a medical examination summary which should include data concerning former diagnostic examinations, detailed description of morphology as well as the location of lesions being diagnosed and suspected of malignant character together with the assessment of their relation to the skin and fascia as well as infiltration of fascia and chest wall. The essential requirement is the analysis of the contrast enhancement curve as well as the appraisal of diffusion limitation with numerical ADC values. Assessment of lymph nodes is also required, as is the classification of lesions into appropriate BI RADS in summary conclusions. In order to avoid significant differences in the phrasing of summaries prepared at particular centers as well as by particular individuals, a general scheme forming a basis for the summary should be adopted or else, a list of questions to be answered in order to make the summary complete, comprehensible and unambiguous should be developed. Such procedures would certainly make the radiologist's work easier; it would also ensure radiographers being better understood by fellow radiographers and clinicians.
Crack velocity dependence of electron emission during fracture of filled elastomers

Field: Materials Science (Physical Sciences)

Abstract In this article we examine the electron emission accompanying the fracture of filled elastomers, where in previous work we have shown the emission to be intense and due predominately to interfacial failure. In this study we show that there is a strong velocity dependence on the rate of electron emission during the propagation of a crack in filled silicone rubber and polybutadiene filled with glass beads. This dependence cannot be explained by a simple proportionality between emission rate and rate of surface area production. We propose that the concentration of free radicals produced by crack propagation increases rapidly with crack velocity which in turn produces more intense electron emission by a chemiemission mechanism.
New Frontiers in Like Kind Exchange for the Oil and Gas Industry

Field: Business, Management and Accounting (Social Sciences)

Abstract As an increasing number of companies divest of non-strategic property and acquire properties that contribute to their operating efficiency, tax-deferred exchanging is becoming a significant strategy. The roots of current tax law regarding Like-Kind Exchanges go back to the early 1920’s but have changed significantly as the tax law has been modified and case law developed in intervening years. Recent regulations have made exchanges much easier and less expensive to administer and broadened the scope of what qualifies as an exchange. Final Like-Kind Exchange tax regulations regarding deferred exchanges were issued in 1991 and 1992. In particular, the introduction of the Qualified Intermediary allows exchanging to be an ongoing corporate strategy rather than a highly customized opportunity. This paper will review the new regulations as they apply to the petroleum industry, give examples showing how effective use of the strategy will preserve much needed capital, and demonstrate how the use of an Intermediary expands the application and flexibility of tax-deferred exchange1 to a very broad spectrum of oil and gas entities. There is a significant benefit in developing a management procedure that regularly determines the applicability of tax-deferred exchange in all sales of assets and implements operational steps to execute an exchange routinely and in compliance with tax regulations.
Observer based adaptive robust control of a class of nonlinear systems with dynamic uncertainties

Field: Computer Science (Physical Sciences)

The discontinuous projection based adaptive robust control (ARC) scheme is generalized to a class of nonlinear systems in an extended semi-strict feedback form by incorporating a nonlinear observer and a dynamic normalization signal. The unmeasured states associated with the dynamic uncertainties are assumed to enter the system equations in an affine fashion. A novel nonlinear observer is first constructed to estimate the unmeasured states for a less conservative design. Estimation errors of dynamic uncertainties, as well as other model uncertainties, are dealt with effectively via certain robust feedback control terms for a guaranteed robust performance. In contrast with existing conservative robust adaptive control schemes, the proposed ARC method makes full use of the available structural information on the unmeasured state dynamics and the prior knowledge on the bounds of parameter variations for high performance. The resulting ARC controller achieves a prescribed transient performance and final tracking accuracy in the sense that the upper bound on the absolute value of the tracking error over entire time-history is given and related to certain controller design parameters in a known form. Furthermore, in the absence of uncertain nonlinearities, asymptotic tracking is also achieved.
Abstract 32: Cardiac Arrest: Who Goes to the Catheterization Lab?

Field: Medicine (Health Sciences)

Introduction: Therapeutic hypothermia (TH) is neuroprotective and increases survival in resuscitated cardiac arrest patients. Approximately 70% of sudden cardiac deaths are caused by coronary heart disease. For patients requiring angiography/PCI, TH can occur simultaneously. Methods: “Cool It” is a comprehensive TH protocol integrated into a regional STEMI network. From Feb 2006 to July 2010, 192 consecutive cardiac arrest patients who remained unresponsive following return of spontaneous circulation were enrolled in the Cool It protocol. Those patients with suspicion for ischemic etiology or evidence of STEMI were transferred directly to the cath lab. Results: On the 192 patients, angiogram was performed in 144 (75.0%). Patients sent for angiography had higher prevalence of initial rhythm VF/VT 116 (80.6%) vs. 19 (39.6%), cardiogenic shock 66 (45.8%) vs. 11 (22.9%), and ST elevation 54 (37.5%) vs. 1 (2.1%) than the 48 patients not undergoing angiography. PCI was performed in 73 (50.7% of patients undergoing angiogram, 38.0% all patients). Of these 73 patients, 64 (87.7%) had initial rhythm VF/VT, 38 (52.1%) were in cardiogenic shock, and 39 (53.4%) had ST elevation. Identified culprit arteries were LAD n=30 (41.1%), RCA n=24 (32.9%), CMX n=12 (16.4%), left main n=4 (5.5%), and none n=3 (4.1%). Mean pre-PCI TIMI flow was 1.36, and post-PCI TIMI flow was 2.91. BMS was used in 31 (42.5%), DES in 40 (54.8%), and one had balloon angioplasty only. Three were referred for CABG. Survival to hospital discharge was 43/73 (58.9%), and survival with favorable neurologic outcome (cerebral performance category 1 or 2) was 39/73 (53.4%). Patients who underwent angiography but did not receive PCI had the similar outcomes: survival was 46/71 (64.8%) and favorable neurologic outcome was seen in 44/71 (62.0%). Patients who did not undergo angiography had the poorest outcome: survival was 11/48 (22.9%) and with favorable neurologic outcome was seen in 9/48 (18.8%). Conclusion: The majority of unresponsive cardiac arrest survivors underwent angiography. Patients who underwent angiography with PCI had the similar outcomes to those with angiography alone. Favorable baseline patient characteristics appear to account for the improved outcomes in the angiography group.