jimnoneill/paper-to-field-training huggingface dataset:
Developing novel antibacterial dental filling composite restoratives

Field: Dentistry (Health Sciences)

A novel antimicrobial dental composite system has been developed and evaluated.Both alumina and zirconia filler particles were covalently coated with an antibacterial resin and blended into a composite formulation, respectively. Surface hardness and bacterial viability were used to evaluate the coated alumina filler-modified composite.Compressive strength and bacterial viability were used to evaluate the coated zirconia filler-modified composite. Commercial composite Kerr was used as control. The specimens were conditioned in distilled water at 37°C for 24 h prior to testing. Four bacterial species Streptococcus mutans, Staphylococcus aureus, Pseudomon asaeruginosa and Escherichia coli were used to assess the bacterial viability. Effects of antibacterial moiety content, modified particle size and loading, and total filler content were investigated.
Chapter 2 describes how we studied and evaluated the composite modified with antibacterial resin-coated alumina fillers. The results showed that almost all the modified composites exhibited higher antibacterial activity along with improved surface hardness, as compared to unmodified one. Increasing antibacterial moiety content, particle size and loading, and total filler content generally increased surface hardness. Increasing antibacterial moiety, filler loading, and total filler content increased antibacterial activity. On the other hand, increasing particle size showed a negative impact on antibacterial activity. The leaching tests indicate that the modified experimental composite showed no leachable antibacterial component to bacteria.
Chapter 3 describes how we studied and evaluated the composite modified with antibacterial resin-coated zirconia fillers. The results showed that almost all the modified composites exhibited higher antibacterial activity along with decreased compressive strength, as compared to the unmodified control. It was found that with increasing antibacterial moiety content and modified filler loading, yield strength,modulus and compressive strength of the composite were decreased. In addition,the strengths of the composite were increased with increasing powder/liquid ratio.On the other hand, with increasing antibacterial moiety content, filler loading and powder/liquid ratio, antibacterial activity was enhanced.
In summary, we have developed a novel antibacterial dental composite system for improved dental restoratives. Both composites modified with the antibacterial resin-coated alumina and zirconia fillers have demonstrated significant antibacterial activities.The composite modified with the alumina fillers showed improved hardness values, but the composite modified with the zirconia fillers showed decreased compressive strength values. It appears that the developed system is a non-leaching antibacterial dental composite.
Otorhinolaryngological Findings in Patients from Southwestern Colombia with Clinical, Enzymatic and Molecular Diagnosis of Mucopolysaccharidosis II, IV-A and VI

Field: Medicine (Health Sciences)

Mucopolysaccharidosis is characterized by excessive accumulation of glycosaminoglycan sulfate in organs and tissues. Otorhinolaryngological and upper respiratory tract pathologies are among the earliest clinical manifestations. We realized a retrospective study of clinical and otorhinolaryngologic findings of 35 patients diagnosed with MPS type II, IV-A and VI of the Colombian southwest. As a result, we found that 64% of the patients evaluated had hearing loss, 11.3% had hypertrophy of the tonsils,17.10% short neck and macroglossia. Additionally, 47.8% of the patients presented otitis media. 20% received treatment with hearing aids. no patient reported otosclerosis or tinittus. In patients with different types of MPS, there is a high frequency and progressive tendency to suffer audiological losses and recurrent infections, so it is important an opportune diagnosis, permanent monitoring and adequate therapy to avoid the repercussion of the pathology in the quality of life of patients.
[Hormonal interrelations in the hypophyseal-ovarian system in heifers during prostaglandin F2-alpha-induced estrus].

Field: Veterinary (Health Sciences)

Study of prostaglandin F2 alpha action, synchronizing the estrus, in experiments on heifers demonstrated that Estrumeit (made by ICI, Great Britain), rostaglandin F2 alpha drug, in a dose of 500 micrograms was an active luteolytic factor, leading to the corpus luteum regress, determined by a fall in the progesteron level in the peripheral blood. During the estrus induction there was a short-term elevation in production and excretion of testosterone, this pointing to the prostoglandins participation in the activation of the androgenic ovarian function. Prolactin hyposecretion was shown to be a necessary condition for the realization of general biological processes for the occurrence of estrus.
Research Update: Programmable tandem repeat proteins inspired by squid ring teeth

Field: Materials Science (Physical Sciences)

Cephalopods have evolved many interesting features that can serve as inspiration. Repetitive squid ring teeth (SRT) proteins from cephalopods exhibit properties such as strength, self-healing, and biocompatibility. These proteins have been engineered to design novel adhesives, self-healing textiles, and the assembly of 2d-layered materials. Compared to conventional polymers, repetitive proteins are easy to modify and can assemble in various morphologies and molecular architectures. This research update discusses the molecular biology and materials science of polypeptides inspired by SRT proteins, their properties, and perspectives for future applications.
Learning - based Adaptation Framework for Elastic Software Systems

Field: Computer Science (Physical Sciences)

Adaptation is a concern for elastic software systems.Conventional methods like Brownout try to deactivate optional computation per request after decoupling the software into different components, to lower the workload when peaks occur.However, resource-intensive components are not always easy to isolate, and some software systems are even not separable.In this paper, we propose a new paradigm that provides each core and mandatory component a corresponding alternative component, with similar function but lower resource consumption, and use reinforcement learning in a feedback loop control for the selfadaptation process.We modified the widely used benchmark RU-BiS to make it weakly coupled and add alternative components.Experiments show that our framework dramatically improves both the efficiency and effectiveness of self-adaptation.
YOSH AVLODNI SOG'LOM MA'NAVIY-AXLOQIY TARBIYALASHDA AXBOROT TEXNOLOGIYALARIDAN FOYDALANISH ZARURIYATI

Field: Social Sciences (Social Sciences)

Ushbu maqolada bugungu kunda ta'lim-tarbiyaviy jarayon sifat va samaradorligini oshirishda zamonaviy axborot texnologiyalaini qo'llash, ta'lim-tarbiya jarayonini kompyuterlashtirishning pedagogik-psixologik jihatlari, axborot texnologiyadan foydalanishning asosiy yo'nalishlari keltirib o'tilgan.
Cooperative simultaneous localization and mapping algorithm based on distributed particle filter

Field: Computer Science (Physical Sciences)

In this article, cooperative simultaneous localization and mapping algorithm based on distributed particle filter is proposed for multi-robot cooperative simultaneous localization and mapping system. First, a multi-robot cooperative simultaneous localization and mapping system model is established based on Rao-Blackwellised particle filter and simultaneous localization and mapping (FastSLAM 2.0) algorithm, and an median of the local posterior probability (MP)-cooperative simultaneous localization and mapping algorithm combined with the M-posterior distributed estimation algorithm is proposed. Then, according to the accuracy advantage of the early landmarks comparing to the later landmarks in the simultaneous localization and mapping task, an improved time-median of the local posterior probability (MP)-cooperative simultaneous localization and mapping algorithm based on time difference optimization is proposed, which optimizes the weights of the local estimation and improves the accuracy of the global estimation. The simulation results show that the algorithm is practical and effective.
SH065441.07FU

Field: Agricultural and Biological Sciences (Life Sciences)

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
Should we consider the infusion of lipid emulsion in the resuscitation of poisoned patients?

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Abstract The use of intravenous lipid emulsions (ILEs) as antidote in local anaesthetic systemic toxicity has gained widespread support following convincing data from animal models, and successful case reports in humans. Proposed beneficial mechanisms of action for ILEs include intravascular sequestration of intoxicant and subsequent enhanced redistribution to biologically inert tissues, augmentation of fatty acid utilisation for ATP synthesis in the context of metabolic poisoning, and direct cardiotonic and ion channel effects. The evidence base for use of ILEs in acute drug intoxication is evolving. The present evidence supports use of ILEs only in local anaesthetic systemic toxicity and in lipophilic cardiotoxin intoxication when there is an immediate threat to life, and other therapies have proven ineffective.
A review of complementary feeding practices in South Africa

Field: Health Professions (Health Sciences)

INTRODUCTION : Infant health and nutrition in South Africa are a priority, as evidenced by the political commitment and policy \ndevelopment history of the last 25 years. Current efforts focus on improving breastfeeding rates, but the action plan for \ncomplementary feeding receives less attention and resourcing. A thorough analysis of the current infant feeding situation is \nrequired to assist with policy and targeted programmes associated with complementary feeding. \nAIM : The aim of this review was to identify and collate all published research in South Africa on the complementary feeding \npractices of infants and young children, aged 0–24 months. \nMETHODOLOGY : Searches included English-language research published between 2006 and 2017, within PubMed, Scopus, Web of \nScience and Google Scholar. All papers included in the review had to meet defined eligibility criteria. Papers older than 11 years \nwere excluded. In total 34 papers relevant to South Africa were identified and included in this review. \nMAIN FINDINGS : Early introduction of foods and liquids other than breast milk is a common practice. Maize porridge is a common \nfirst food for infants, but there is also a high reliance on commercial infant cereal. Water and other liquids (e.g. tea, herbal \nmixtures) are commonly given to infants younger than six months. There is little information on the number of meals per \nday. The diets of many older infants do not meet the criteria for a minimally acceptable diet. Few animal source foods are \nused in complementary feeding. There are indications that processed meats, soft drinks, sweets and salty crisps are given \nregularly to older infants between six months and one year. \nCONCLUSION : Complementary feeding practices in South Africa are suboptimal and appropriate action is needed to improve this \nsituation. Further investigation is needed on whether older infants and young children can achieve their required dietary intakes \nfrom the food that is available to them. If a change in older infant and young child feeding behaviour is desired, then existing \nmethods and approaches need to change.
A Generalized Attention Mechanism to Enhance the Accuracy Performance of Neural Networks

Field: Computer Science (Physical Sciences)

In many modern machine learning (ML) models, attention mechanisms (AMs) play a crucial role in processing data and identifying significant parts of the inputs, whether these are text or images. This selective focus enables subsequent stages of the model to achieve improved classification performance. Traditionally, AMs are applied as a preprocessing substructure before a neural network, such as in encoder/decoder architectures. In this paper, we extend the application of AMs to intermediate stages of data propagation within ML models. Specifically, we propose a generalized attention mechanism (GAM), which can be integrated before each layer of a neural network for classification tasks. The proposed GAM allows for at each layer/step of the ML architecture identification of the most relevant sections of the intermediate results. Our experimental results demonstrate that incorporating the proposed GAM into various ML models consistently enhances the accuracy of these models. This improvement is achieved with only a marginal increase in the number of parameters, which does not significantly affect the training time.
Synthesis, characterization, and evaluation of novel cell‐penetrating peptides based on TD‐34

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

In this study, six N‐1, N‐2, or N‐11 derivatives of TD‐34 (a cationic cyclic cell‐penetrating peptide [CPP], ACSSKKSKHCG) were designed and synthesized including both linear peptides and cyclic peptides, such as DL‐1 (KWSSKKSKHCG), DLCC‐1 (cyclopeptide, KWSSKKSKHCG), DL‐2 (KWSSKKSKHCG‐NH 2 ), DLCC‐2 (cyclopeptide, KWSSKKSKHCG‐NH 2 ), DL‐3 (RWSSKKSKHCG), and DLCC‐3 (cyclopeptide, RWSSKKSKHCG). The cyclic peptides were synthesized by disulfide bound linkages formed by N‐2 and N‐10 cysteine. In vitro penetration experiment was conducted to investigate the transdermal enhancement ability of these derivatives, using triptolide (TP) as model drug. The results display that at the presence of DLCC‐2, the accumulative penetration amount of TP increased 1.71‐fold ( P < .05) within 12 hours, displaying better transdermal enhancing ability than TD‐34. Meanwhile, DL‐3 and DLCC‐3 slightly decreased the transdermal delivery of TP, and the presence of DL‐1 and DLCC‐1 shows no obvious effect. In order to clarify the factors on the transdermal ability of peptides, the solubility of TP in phosphate buffer saline (PBS) at the presence of different peptides and the mechanism of transdermal delivery of CPPs was investigated. The result shows that most of these peptides have no significant effect on the solubility of TP except DLCC‐3 (the solubility of TP slightly increased). And in order to investigate transdermal absorption route of DLCC‐2, polyarginine linked to rhodamine b (Rh b) derivative is used. The result proved that the transdermal route of polyarginine is via hair follicle, which may change the transdermal route of its cargo molecule (TP). Our group previously proved that polyarginine and TD‐34 have similar transdermal enhancing mechanism (changing the transdermal route of their cargo molecule); it is reasonably speculated that the transdermal route of DLCC‐2 is the same as polyarginine and then changes the transdermal absorption route of TP. Furthermore, such results have laid a solid foundation for further investigation of CPPs and paved a way for both designing and synthesizing of new drug delivery system for therapy molecules.
Protective effect of gypenosides-containing serum against oxidation neurotoxicity induced by glutamate

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective To investigate the neuroprotective effects of gypenosides (GP) containing serum on glutamate(Glu) induced oxidation toxicity to cortical neurons.Methods Sera containing GP was collected by way of seropharmacology,and the primary cortical neurons isolated from Wistar rats E14-15d embryos were studied.The viability of cells was detected by the MTT method,the cellular death pathway was analyzed by Ho33342 and the PI double-labeled method,the contents of SOD and GSH were determined by a biochemistry method,and Cytosolic [Ca2+] was determined by flow cytometry(FCM).Results Compared with Glu,GP-containing serum could increase the cell survival rate and block the decrease of SOD and GSH and the increase of cytosolic.Conclusions GPcontaining serum can protect the neurons from damage of glutamate oxidative neurotoxicity and the 400 mg/kg/d GP-containing serum has the strongest antagonistic action.
REAKSI INVESTOR TERHADAP INFORMASI PENINGKATAN KASUS HARIAN COVID-19 PADA EMITEN PENYEDIA JASA KESEHATAN BEI

Field: Economics, Econometrics and Finance (Social Sciences)

COVID-19 pandemic have impact on the economy, We can see from the IDX stock market crash, that can be observed from january 2020 untill march 2020. When COVID-19 pandemic occur, there was an increase demand for health product. That can be showed by how the company revenue increased on health service company, then how the investor respond to that?. This study aims to observe the investor reactions, on increasing COVID-19 cases to returns, abnormal returns and trading volume activity of Health Service Providers based company, with a period of 10 days before and after the announcement of the event. This study uses an Event Study approach. The result of this study is that there are significant differences in the before and after period on return and abnormal return, and not significant on trading volume activity variables. There are three implications obtained from this study, the first is that this research confirms that information affects stock prices. The second implication is that the significant increase in returns and abnormal returns does not mean that trading volume activity has also increased significantly. The final implication of this research is that the alleged inclination of investors irrationality.
The relationship between eating disorder symptomology, body image concerns, and early maladaptive schemas

Field: Psychology (Social Sciences)

This study examined the relationship between eating disorder symptomology, body image concerns, and early maladaptive schemas. The specific eating disorder symptoms were binging, purging and restricting. Participants were undergraduate college women. Eating disorder symptomology was measured along a continuum so that the sample encompassed individuals with eating disorder pathology ranging from asymptomatic to severe symptoms. Multiple regression analyses indicated that body image concerns predicted a significant proportion of variance in binging, purging and restrictive behaviors. Specifically, shape concerns predicted significant unique variance in restrictive behaviors. Early maladaptive schemas were found to account for a significant proportion of variance among restrictive behaviors only. Specific early maladaptive schemas that accounted for significant unique variance included unrelenting standards and admiration seeking. Findings offer continued support for the importance of body image concerns in the development and maintenance of eating disorder symptomology. In contrast, findings suggest that the relationship between early maladaptive schemas and eating disorder symptomology is less clear and may only be significant to restrictive behaviors.
Activation of Complement by Blood Transfusion Filter1

Field: Medicine (Health Sciences)

Abstract. Fresh blood, stored blood and granulocyte concentrates were passed through 170‐μm and microaggregate blood filters to determine the degree of complement activation that occurs during transfusion of citrated blood products. Complement activation was assessed by measurement of C3 conversion using crossed immunoelectrophoresis and by assessment of C5a using a leukocyte aggregation functional assay. Prefiltration, fresh or stored blood products showed 0–1% C3 activation. Postfiltration, the degree of C3 conversion did not change for fresh blood or granulocyte concentrates. For stored whole blood, the degree of C3 conversion increased slightly to 2–3%. Prefiltration results for all samples showed a low level of C5a which did not change after passage through any filter. Serum incubated with filter material at 37 °C showed 2–10% C3 conversion. In contrast, results with citrated plasma showed less than 3% conversion of C3. We conclude that although some filter materials may activate complement in serum, filtration of citrated blood products through microaggregate blood filters induces little complement activation.
ChemInform Abstract: A Facile and Convenient Synthetic Method for N‐β‐ Trifluoroacetylvinyl Amino Acid Esters, α‐Aminoacetophenones, and Aminoacetonitriles as Potenitally Useful Precursors of Fluorine‐ Containing Pyrroles.

Field: Chemistry (Physical Sciences)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
CBSE 12 Math Survival Guide Differential Equations By Prof. Subhashish

Field: Mathematics (Physical Sciences)

IIT-JEE main and advanced, CBSE Standard 12 Math Survival Guide-Differential Equations by Prof. Subhashish Chattopadhyay SKM Classes Bangalore Useful for I.Sc. PU-II AP-Maths IGCSE IB AP-Mathematics, State Board or High School exams, College Math exams and other exams.This free e-Book covers how to eliminate unknown constants and make a Differential equation, Order and Power of Differential Equations, Types of Differential Equations, such as ( Variable Separable type, Reducible to Variable Separable by substitution, Exact type, Integrating Factor for Exact type, Reducible to exact, Linear, Bernoulli type, Homogeneous, Reducible to Homogeneous etc )Several tough examples makes this a good preparation and Reference material for Exams.
Encouraging knowledge sharing behavior through team innovation climate, altruistic intention and organizational culture

Field: Business, Management and Accounting (Social Sciences)

The purpose of this study is to investigate the relationships among team innovation climate, altruistic intention, creative culture, and knowledge sharing behavior of employees. A survey-base study was conducted with 319 software managers working in teams in Pakistan. The results of this study revealed that team innovation climate had positive impact on altruistic intention and knowledge sharing behavior. Moreover, altruistic intention and organizational culture had positive impact on knowledge sharing behavior. Limitation of the study and recommendations for future study are also discussed.
Research on the Test-Execution Based Failure Data Modeling

Field: Computer Science (Physical Sciences)

At present, software reliability researchers and engineers are desperately hindered by the lack of failure data. In this paper, the authors present a model, which is called JBFDM (Jade Bird failure data model), for failure data based on the study and analysis of the relationship between software testing and reliability estimation. Furthermore, based on the model JBFDM, an approach of carrying out failure data collection and management is also proposed, and a data collection tool, which is called JBFDCollector is presented.