jimnoneill/paper-to-field-training huggingface dataset:
Analysis of the Relationship between Chronic Diseases and Grip Strength of the Korean Senior Citizens: Focusing on Hypertension and Diabetes

Field: Medicine (Health Sciences)

노인의 근력은 일반적인 건강과 비례하며, 심혈관 질환 유병율 및 사망률과 관계가 매우 높다. 이에 본 연구에서는 만성질환 중 고혈압, 당뇨병을 앓고 있는 한국 노인들의 악력을 비교분석하여, 노인 건강을 위한 기초자료로 제공하고자 한다. 연구 대상자는 국민건강영양조사에서 심뇌혈관질환이 없는 노인 1,858명(남 843, 여 1,015)을 정상군, 고혈압군, 당뇨군, 복합군으로 분류하였으며, 자료분석은 SAS 9.4를 이용하여 기초통계분석 및 일반선형모형(general linear model)과 Rao-Scott 카이제곱 검정(chi-square test)을 실시하였다. 분석 결과, 남녀 모두 질환에 따른 체중당 악력이 유의하게 차이가 나타났으며, 군간 차이를 분석한 결과 남자는 건강군>복합군, 고혈압군>복합군, 당뇨군>복합군, 여자는 건강군>당뇨군, 건강군>복합군, 고혈압군>복합군에서 유의한 차이가 나타났다(p<.05). 결론적으로 노인의 만성질환은 악력과 관계가 높으며, 고혈압과 당뇨병을 함께 갖는 경우는 악력이 더 낮아짐을 확인하였다. 이러한 결과는 한국 노인에게 고혈압, 당뇨병과 관련된 건강지표로 악력이 유용하게 사용 될 것으로 생각되며, 노인에게 근력의 중요성을 재확인할 수 있는 기초자료로 도움이 될 것이다.This research aims to provide basic materials for the health of the elderly by conducting a comparative analysis of the grip strength of Korean senior citizens with hypertension and diabetes. A total of 1,858 seniors (male 843, female 1,015) with hypertension or diabetes based on the Korea national health and nutrition examination survey (KNHNES) were compared to the control group. Data analysis employed SAS 9.4, and basic statistical analysis, general linear model (GLM), and the chi-square test were conducted. As a result, both male and female groups had significantly different grip strength according to the disease. Significant differences were found healthy group>complex group, hypertension group>complex group, diabetes group>complex group in male and healthy group>diabetes group, healthy group>complex group, hypertension group >complex group in female (p<.05). In conclusion, it was confirmed that chronic disease of the elderly has a strong relation with grip strength, and the grip strength is lower when hypertension and diabetes are combined. Such a result is thought to be useful for elderly Koreans as a health indicator for hypertension and diabetes, and it will be useful as a basic resource to reconfirm the importance of muscle strength for the elderly.
Characterization of teaching practices that facilitate or limit student participation from a gender perspective. A case study for the training of physical education and mathematics teachers in a regional university in Chile

Field: Social Sciences (Social Sciences)

The study addresses from a gender perspective, the scope of the practices that university teachers have implemented in Initial Teacher Education. The main objective was to know the teaching practices in the university and school classroom, which facilitated and/or limited the participation of students from the experience of those who have lived them as students of Secondary Education Pedagogy in Mathematics and Physical Education Pedagogy. This is a multiple case study, with a qualitative approach. The results show the presence of various teaching practices in which both the absence of a gender approach and the persistence of an acceptance of certain gender roles and stereotypes that continue to be transmitted in university and school classrooms are evident. Although future teachers of Mathematics and Physical Education are clearly aware of the characteristics of these practices and the discrimination associated with some of them, new challenges arise from this study to promote changes in initial teacher training which will allow young people to be agents of the social transformation required in terms of gender equity in education.
Additional file 2 of Novel humanized monoclonal antibodies for targeting hypoxic human tumors via two distinct extracellular domains of carbonic anhydrase IX

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Additional file 2 Table 1. SPR data from the analysis of twenty-five CA9hu-1 and CA9hu-2 variants expressed as KD values. Chimeric HC0LC0 antibodies HC0LC0 antibodies (having the murine variable domains and the human Ig constant domains) were used as reference samples.
Introducing The Bartopsi.com - The World's Leading Accurate "bar To Psi" Converter Website

Field: Computer Science (Physical Sciences)

Welcome to the Bartopsi.Com website, the world&#39;s leading accurate &quot;bar to psi&quot; converter website. Our app allows you to quickly and easily convert between bar and psi.&nbsp;We hope you find our website helpful and that we can help you in your quest to become more knowledgeable about atmospheric pressure and its effects on your physical and emotional health.
Supramolecular Assemblies of 3/4-Chlorobenzoic Acid and Amino-Chloropyridine Derivatives: Synthesis, X-ray Diffraction, DFT Calculations, and Biological Screening

Field: Chemistry (Physical Sciences)

Organic acids (3-chlorobenzoic acid and 4-chlorobenzoic acid) were treated with 4-amino-2-chloropyridine and 2-amino-4-chloropyridine as coformers for cocrystallization. Acid/base pairs afforded a cocrystal (3-chlorobenzoic acid and 4-amino-2-chloropyridine, compound 1) and molecular salts (2-amino-4-chloropyridinium 3-chlorobenzoate, 2; 2-amino-4-chloropyridinium 4-chlorobenzoate, 3). The products were characterized with the help of FT-IR, UV/visible spectroscopy, PXRD, and SC-XRD. The position of the Cl-substituent on the phenyl ring was explored with respect to proton transfer between acid/base pairs, and its role in supramolecular chemistry is discussed in detail. The existence of supramolecular assemblies was further reproduced using DFT calculations. Further, frontier molecular orbital (FMO), molecular electrostatic potential (MEP), and noncovalent interaction index (NCI) analyses were performed to gain insight into the electronic properties and nature of noncovalent interactions. The prepared compounds were examined for their biological activities against selected Gram-positive and Gram-negative bacterial strains and were also tested as antioxidant agents (DPPH free radical scavenging). Structural parameters determined experimentally and theoretically are within the expected range, and the biological activities of the resultant compounds are moderate.
Mexican temporary migrants in Canada: a sociolinguistic approach

Field: Social Sciences (Social Sciences)

Mexican temporary migrants in Canada: a sociolinguistic approach Canada is well recognized because of its immigration policies and settlement programs that include ESL classes that help newcomers in its adaptation and integration process, recognizing in this way that linguistic competence is crucial for the social inclusion and engagement of migrants. However, migratory laws do not contemplate these kinds of help for temporary migrants that come from Mexico and the Caribbean through the Seasonal Agricultural Workers Program (SWAP). The SWAP has been a source of relevant economical, political, and social research with important policy implications. Within the literature, language barriers have always been mentioned as a major problem of this population because it amplifies migrants’ challenges of social and work needs, relations and adaptation, but there is no evidence of sociolinguistic research. In my study, I pretend to study the sociolinguistic situation of the SAWP workers from Mexico through a sociolinguistic census that will be applied to one hundred participants along five chosen cities in two Canadian provinces, where I will compare language acquisition and/or attrition and it’s relationship to workers’ exclusion, linguistic adaptation, attitude, identity and vulnerability, considering social variables such as age, sex, place of origin, education, literacy level, income, social networks, ESL access, Spanish literacy access, language brokers, ITS access, etc. I assume that some of my findings will be that the deficient or inexistent linguistic competence of the language of the majority in an environment of language contact is a manifestation of exclusion and segregation of the Mexican seasonal agricultural workers in Canada.
Liposome Loaded Ion/Temperature Dual Responsive Gellan Gum Hydrogel as Potential Nasal-To-Brain Delivery System

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Intranasal administration, which can bypass the blood–brain barrier (BBB), is widely recognized as a promising strategy for high-efficiency drug delivery to the brain. Herein, for the purpose of effectively delivering drugs to the brain via intranasal administration, glutathione (GSH)-modified gellan gum (GSH-GG) with ion/temperature dual responsive properties was synthesized and encapsulated on galanthamine hydrobromide (GH)-loaded liposomes (GH-Lipo) for effective GH delivery to the brain (GH-Lipo@GSH-GG). Our results demonstrated that GSH-GG greatly decreased the gelation temperature of GG from 44.0 °C to 22.1 °C without compromising its ion responsiveness. Moreover, GSH-GG had a good protection ability for GH-loaded liposomes without affecting its drug release. Most importantly, the finally obtained GH-Lipo@GSHGG showed acceptable targeted delivery of GH to the brain upon in vivo administration. Therefore, this formulation can be employed as a potential delivery system in nasal-to-brain delivery.
A renormalisation-group approach to two-body scattering with long-range forces

Field: Physics and Astronomy (Physical Sciences)

We apply the renormalisation-group to two-body scattering by a combination of known long-range and unknown short-range forces. A crucial feature is that the low-energy effective theory is regulated by applying a cut-off in the basis of distorted waves for the long range potential. We illustrate the method by applying it to scattering in the presence of a repulsive 1/r^2 potential. We find a trivial fixed point, describing systems with weak short-range interactions, and a unstable fixed point. The expansion around the latter corresponds to a distorted-wave effective-range expansion.
Figure S1 from Depletion of Adipose Stroma-Like Cancer-Associated Fibroblasts Potentiates Pancreatic Cancer Immunotherapy

Field: Medicine (Health Sciences)

<p>A, Fig. 1 schematic of testing the effect of Pdgfrb+ CAF depletion on PDAC progression. B, initial body weight in experiment A. C, experiment A tumor section H&E staining showing inflammation (i), necrosis (n), and well-differentiated tumor cells (arrows). D, schematic of testing the effect of Pdgfrb + CAF pre-depletion on PDAC progression. E, initial body weight in experiment D. F, tumor weights in experiment D. G, Fig. 2 schematic testing the effect of ASC-like CAF depletion on PDAC progression. H, initial body weight in experiment G. I, experiment G tumor section H&E staining indicating necrosis (n) and well-differentiated tumor cells (arrows). Scale Bars = 500μm. *=p<0.05.</p>
Diagnosis and treatment of unexplained anemia with iron deficiency without overt bleeding.

Field: Medicine (Health Sciences)

A general overview is given of the causes of anemia with iron deficiency as well as the pathogenesis of anemia and the para-clinical diagnosis of anemia. Anemia with iron deficiency but without overt GI bleeding is associated with a risk of malignant disease of the gastrointestinal tract; upper gastrointestinal cancer is 1/7 as common as colon cancer. Benign gastrointestinal causes of anemia are iron malabsorption (atrophic gastritis, celiac disease, chronic inflammation, and bariatric surgery) and chronic blood loss due to gastrointestinal ulcerations. The following diagnostic strategy is recommended for unexplained anemia with iron deficiency: conduct serological celiac disease screening with transglutaminase antibody (IgA type) and IgA testing and perform bidirectional endoscopy (gastroscopy and colonoscopy). Bidirectional endoscopy is not required in premenopausal women < 40 years of age. Small intestine investigation (capsule endoscopy, CT, or MRI enterography) is not recommended routinely after negative bidirectional endoscopy but should be conducted if there are red flags indicating malignant or inflammatory small bowel disease (e.g., involuntary weight loss, abdominal pain or increased CRP). Targeted treatment of any cause of anemia with iron deficiency found on diagnostic assessment should be initiated. In addition, iron supplementation should be administered, with the goal of normalizing hemoglobin levels and replenishing iron stores. Oral treatment with a 100-200 mg daily dose of elemental iron is recommended (lower dose if side effects), but 3-6 months of oral iron therapy is often required to achieve therapeutic goals. Intravenous iron therapy is used if oral treatment lacks efficacy or causes side effects or in the presence of intestinal malabsorption or prolonged inflammation. Three algorithms are given for the following conditions: a) the paraclinical diagnosis of anemia with iron deficiency; b) the diagnostic work-up for unexplained anemia with iron deficiency without overt bleeding; and c) how to proceed after negative bidirectional endoscopy of the gastrointestinal tract.
Freezing Flexible Vesicles

Field: Physics and Astronomy (Physical Sciences)

The freezing transition of tensionless fluctuating vesicles is investigated by Monte Carlo simulations and scaling arguments for a simple tether-and-bead model of fluid membranes. In this model a freezing transition is induced by reducing the tether length. The membrane is shown to be in a hexatic phase for small tether lengths. With decreasing bending rigidity, the hexatic-fluid transition occurs at smaller and smaller tether lengths.
Social experience during adolescence in female rats increases 50 kHz ultrasonic vocalizations in adulthood, without affecting anxiety‐like behavior

Field: Neuroscience (Life Sciences)

Abstract Adolescents are highly motivated to engage in social interactions, and researchers have hypothesized that positive social relationships during adolescence can have long term, beneficial effects on stress reactivity and mental well‐being. Studies of laboratory rodents provide the opportunity to investigate the relationship between early social experiences and later behavioral and physiological responses to stressors. In this study, female Lister‐hooded rats ( N = 12 per group) were either (a) provided with short, daily encounters (10 min/day) with a novel partner during mid‐adolescence (postnatal day 34–45; “social experience,” SE, subjects) or (b) underwent the same protocol with a familiar cagemate during mid‐adolescence (“control experience,” CE, subjects), or (c) were left undisturbed in the home cage (non‐handled “control,” C, subjects). When tested in adulthood, the groups did not differ in behavioral responses to novel environments (elevated plus maze, open field, and light‐dark box) or in behavioral and physiological (urinary corticosterone) responses to novel social partners. However, SE females emitted significantly more 50 kHz ultrasonic vocalizations than control subjects both before and after social separation from a familiar social partner, which is consistent with previous findings in male rats. Thus, enhanced adolescent social experience appears to have long‐term effects on vocal communication and could potentially modulate adult social relationships.
Phylloplane microfungal metabolite influences activity of RuBisCO

Field: Agricultural and Biological Sciences (Life Sciences)

AbstractThe phylloplane microbes are known to affect systemic acquired resistance in plants against a broad spectrum of pathogens. The influence of phylloplane microbes and their metabolites on physiology and biochemistry of plants is well-documented but their effect on the physiology and functioning of chloroplasts and mitochondria is not well understood. The present study was conducted to understand the impact of metabolite of a dominant phylloplane microfungi (Fusarium oxysporum) isolated from the phylloplane of Lycopersicon esculentum on activity of RuBisCO. Activity of RuBisCO (EC 4.1.1.39) in chloroplasts of fungal metabolite treated and untreated eight-week old tomato plants were studied. Significant increase in the activity of RuBisCO (P ⩽ 0.01), isolated from plants inoculated with the fungal metabolite was observed. The fungal metabolite could elicit the enzyme activity by about two folds (P ⩽ 0.05) within 72–96 h of treatment of tomato plants. The result demonstrates that probably phylloplane microfungi and/or their metabolites influence the photosynthetic efficiency of plants.Keywords: phylloplaneRuBisCOmetabolitesenzyme activityFusarium oxysporum AcknowledgementThe authors would like to sincerely thank Amity Institute of Biotechnology, Amity University Uttar Pradesh, India for providing the necessary infrastructural facilities and DST-INSPIRE for providing Junior Research Fellowship to the first author.
An Alternative to See-Saw

Field: Physics and Astronomy (Physical Sciences)

We give a new mechanism for generating very small, and almost degenerate, neutrino masses, without resorting to the see-saw mechanism or unnatural small Yukawa couplings. It requires the existence of at least 4 families with an almost democratic structure for the Yukawa couplings. It is also proven that this structure can account for large lepton mixings of the three light leptons.
Monitoring cancer through the blood

Field: Medicine (Health Sciences)

Tumor biopsies remain the gold standard for the evaluation of genetic changes in tumors either at diagnosis or after treatment with targeted therapies. However, this is not always feasible and can seldom be performed more than once. Noninvasive techniques that measure the allelic burden in blood have the potential to realize genotype‐directed cancer therapy. These technologies can potentially be used for noninvasive tumor genotyping and also provide an opportunity for disease monitoring. Several non‐invasive genotyping technologies are currently under development and being evaluated in patients treated with targeted therapies.
Sarcina ventriculi a rare pathogen

Field: Veterinary (Health Sciences)

"Sarcina ventriculi is a gram-positive bacterium, able to survive in extreme low pH environment. It’s first description dates from 1842, by John Goodsir. Since then, just a few cases have been reported. In veterinary medicine, especially in ruminants, it causes bloating, vomiting, gastric perforation and death of the animal. It is commonly associated with delayed gastric emptying or obstruction to gastric outlet, although it’s pathogenicity in humans is not fully understood. We report two cases with identification of the bacteria in gastric specimens stained with hematoxylin-eosin staining, in different clinical settings. The first patient is a young female patient, presenting cardiac arrest and death after gastric perforation and the second patient an adult male presenting with gastric adenocarcinoma, treated with partial gastrectomy followed by adjuvant chemoradiation. In our literature review, we identified forty-five cases reporting Sarcina ventriculi appearance, with a sudden increase since 2010."
[Frequency of myelodysplasia in the GDR (author's transl)].

Field: Medicine (Health Sciences)

All living children suffering from myelomeningoceles and being 1 to 12 years old were registered by means of a questionnaire. The death certificates of all those children who came to death from myelomeningoceles between 1973 and 1977 were also evaluated. Ratio of morbidity: 6 to 10000 live born children. In the first year of life the mortality rate amounted to 34%.
Studies on a common source epizootic of bovine salmonillosis in Manitoba

Field: Veterinary (Health Sciences)

During a period from January to June, 1966, a severe outbreak of bovine salmonellosis occurred in Manitoba. The disease was diagnosed clinically in approximately 50 herds. Salmonella organisms were isolated from carcasses or specimens on 24 different farms involving approximately 2,379 cattle the most frequently isolated serotype was S. newport (92 per cent). The source of infection was traced to bonemeal and mineral supplements. The bonemeal and one of the mineral mixtures originated at one local feed mill. Out of 20 bonemeal samples collected at the affected farms during or shortly after outbreaks occurred, 19 yielded Salmonella organisms, most of which contained more than one serotype. Cultures of three mineral samples were also positive for Salmonellae. The serotypes isolated from cattle corresponded with those isolated from unused portions of bonemeal or mineral on 16 premises... Salmonella organisms (including S. newport) were isolated from bonemeal samples at retail outlets, bags stored at the feed mill and the environment of the mill. Bones used for the production of the bonemeal and other animal by-products used as feed ingredients were collected from two rendering plants which supplied the feedmill and these were positive for Salmonellae. There was a 100 per cent increase in 1966 in the incidence of human infections with S. newport in Manitoba compared to the previous year... Stricter sanitary conditions in rendering plants and feed mills could prevent similar recurrences of contamination of animal feeds with Salmonellae. This in turn would reduce the risk of infection in animals and man.
Effect of Acupressure on Dyspnea and Fatigue among Patients with Chronic Obstructive Pulmonary Disease

Field: Health Professions (Health Sciences)

Background : Chronic obstructive pulmonary disease (COPD) is a leading public health concern worldwide. Dyspnea and fatigue considered the most common health problems among the COPD patients. Although pharmacologic management of COPD is of proven benefit, but it does not help all patients, therefore the aim of the current study was to examine the effect of acupressure on dyspnea & fatigue among patients with chronic obstructive pulmonary disease. Methodology : A quazi – experimental design was utilized to accomplish this study, the sample of 40 adult male and female patients were recruited and randomly assigned equally into study or control group, the control group received the traditional management while study group received traditional management plus acupressure, the study conducted at chest unit and two medical units in Kasr Al-Aini hospital. Five tools were utilized to collect data included socio-demographic data sheet, The University of California at San Diego (UCSD) Shortness of Breath Questionnaire, Fatigue severity scale (FSS), respiratory rate and O2 saturation sheet and 6 minute walk distance (6MWD). Patients in both groups observed for four weeks. Results: The study results concluded that there was a statistical significant difference between study and control group in relation to dyspnea by the end of the 4 th week and respiratory rate & oxygen saturation by the end of the 2 nd & 4 th week. However, there was no statistical significant difference between the two groups in relation to fatigue and 6 MWD test. Conclusion : the study results concluded that acupressure may be effective as an adjuvant therapy to the traditional management for COPD patients to improve dyspnea, respiratory rate and oxygen saturation, while acupressure has no significant effect on fatigue or to improve distance of patients walk. Recommendation : Prospective study should be designed to determine the stability of the effect of acupressure as an adjuvant to control dyspnea. In addition, further studies may be needed with different acupressure points may be recommended to treat fatigue among those patients. Keywords : acupressure, COPD, fatigue, dyspnea.
Tropical Ginger Cultivation in North American Temperate Climes

Field: Agricultural and Biological Sciences (Life Sciences)

The popularity of gingers, in the family Zingiberaceae and many native to Southeast Asia, is increasing as more species are brought into cultivation by botanists and as botanic gardens increase their public displays in glasshouses and outside beds. Not only are the foliage and flowers striking in appearance with bright colors and unusual forms, but many have medicinal uses as well. Some species are evergreen while others go dormant during the winter months. Gingers are relatively easy to cultivate and are not prone to insect pests. In regions with freezing temperatures during the winter a glasshouse is required. With proper care and planning, a great variety of species can be successfully cultivated and put on view for the public.