jimnoneill/paper-to-field-training huggingface dataset:
RegK-Means: A Clustering Algorithm Using Spatial Contiguity Constraints for Regionalization Problems

Field: Computer Science (Physical Sciences)

Regionalization embraces many problems in which the recognition and analysis of patterns in geographic regions is necessary. Clustering techniques and some optimization methods offer algorithms and tools to facilitate this task, and AZP (Automatic Zoning Problem) is one of these optimization methods. In this work, we use semi-supervised clustering by adapting K-Means for regionalization, which was not previously explored. For this purpose, we specified contiguity constraints based on a neighborhood representation. The proposed algorithm is called RegK-Means. Experimental results using three real datasets show improvement in intra-cluster variance, minimization of objective function and computational time improvement compared to AZP.
Additional file 5: Table S2. of Molecular phylogeny reveals food plasticity in the evolution of true ladybird beetles (Coleoptera: Coccinellidae: Coccinellini)

Field: Agricultural and Biological Sciences (Life Sciences)

The best (BIC) multiple sequence alignment partitioning scheme with corresponding substitution models generated with PartitionFinder (version 1.1.1; [41]). (TXT 2 kb)
Numerical aspects in time domain modelling of arbitrarily curved thin wire antennas

Field: Engineering (Physical Sciences)

This paper deals with the numerical modelling of arbitrarily shaped curved antennas by marching on in time (MoT) technique. This time domain version of the method of moments (MoM) is particularly suitable for transient analysis and, in this respect, is more efficient than the frequency domain approach. It produces an iterative algorithm which can be easily computed without inversion of matrices. Actually, in spite of its advantages it is not widely used to analyse structures with arbitrary shape because it involves stability and numerical convergence problem. This work presents a detailed analysis of such problems and provides general rules to characterize thin wire structures. In particular dipole, loop and helical antennas are studied, because they are involved in electromagnetic compatibility (EMC) problems of coupling between the radiation of hand set antennas and human head. Copyright © 1999 John Wiley & Sons, Ltd.
First Report of <I>Hestiasula castetsi</I> (Bolivar, 1897) from Kerala, India with Description of Unique Male Specimens (Mantodea: Hymenopodidae: Acromantinae)

Field: Agricultural and Biological Sciences (Life Sciences)

The praying mantid species Hestiasula castetsi Bolivar (1897) belonging to the family Hymenopodidae is reported for the first time from Kerala, India with the description of the unique male. Two male specimens were collected from the Aralam Wildlife sanctuary of Kannur district, Kerala located in the southern Western Ghats. This species is diagnosed by the general form, by the very different form of frontal sclerite, wings and prolonged titillator of the genital. The genital of this species is quite unique and hence its placement under genus Hestiasula needs future research.
Low Crude Protein Diet Affects the Intestinal Microbiome and Metabolome Differently in Barrows and Gilts

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract Background Low protein diets are commonly used in the growing-finishing pig stage of swine production; however, the effects of low dietary protein on the intestinal microbiota and their metabolites, and their association with pig sex, remain unclear. The present study aimed to assess the impact of a low crude protein (CP) diet on the gut microbiome and metabolome, and to reveal any relationship with sex. Results Barrows and gilts (both n= 24; initial body = 68.33 ± 0.881 kg) were allocated into two treatments according to sex. The four groups comprised two pairs of gilts and barrows fed with a high protein diet (HPD, CP 17% at stage Ⅰ; CP 13% at stage Ⅱ) and a low protein diet (LPD, CP 15% at stage Ⅰ; CP 11% at stage Ⅱ), respectively, for 51 d. Eight pigs in each group were slaughtered and their colon contents were collected. Intestinal microbiota and their metabolites were assessed using 16S rRNA sequencing and tandem mass spectrometry, respectively. The LPD increased intestinal microbiota species and richness indices significantly in both sexes compared with the HPD. The Sample Shannon index was significantly different between barrows and gilts. At the phylum level, the LPD increased the relative abundance of Actinobacteria significantly. The influence of dietary protein levels on Proteobacteria and Synergistetes were associated significantly with sex. At the genus level, Clostridiales, Neisseria, and Prevotellaceae were affected significantly by dietary protein levels. In the latter two genera, the effects were significantly different between barrows and gilts. Metabolomic profiling indicated that dietary protein levels mainly affected intestinal metabolites in gilts rather than barrows. A total of 434 differently expressed metabolites were identified in gilts fed the two protein diets. Correlation analysis identified that six differentially abundant microbiota communities were closely associated with twelve metabolites that were enriched for amino acids, inflammation, immune, and disease-related metabolic pathways. Conclusions These results suggested that decreasing dietary protein contents benefitted the intestinal microbiota in growing-finishing pigs, which selectively affected the microbiota and metabolite profiles in gilts.
Relationship Between Economic Climate and the Level of Barriers to Doing Business in the Services Sector in the EU Countries

Field: Economics, Econometrics and Finance (Social Sciences)

Abstract Development of the whole economy and sectors of the economy is influenced by cyclical fluctuations, what can be observed as slowdown or acceleration of the economic processes. The identification of the leads and lags between the economic indicators, that reveals cyclical fluctuations is very important. The paper attempts to diagnose the lead and lag relationship between the economic sentiment indicators and the indicators of barriers to doing business in the services sector. The growth cycle approach was applied in the paper. A cross correlation analysis was conducted to identify the lead / lag relationship between the variables. The results of the analysis enable to conclude if the confidence indicator is a leading or lagged indicator and what is the length of lead / lag in relation to the indicators of barriers to doing business in the services sector in the EU countries. The study indicate the number of quarters from the peak or through of the business cycle in the services sector after that the level of factors limiting business activity will start to grow or drop. The results of the study can be useful both to the managers of firms as well as the governments.
A screening method for biotinidase deficiency in newborns.

Field: Medicine (Health Sciences)

Abstract We describe a method for neonatal screening for biotinidase (EC 3.5.1.12) deficiency. Biotinidase activity is assessed colorimetrically from dried samples of whole blood spotted on the same filter papers as used in the neonatal screening for phenylketonuria. After the reaction, samples from normal infants are characteristically purple, whereas those from affected individuals are straw-colored. To confirm the deficiency, the enzyme is quantitatively assayed in additional blood spots or serum. A pilot study has been initiated with samples obtained by the Commonwealth of Virginia for phenylketonuria testing.
2133-LB: Engineering Islet Tolerance in Nonobese Diabetic (NOD) Mice via Costimulation Blockade Nanotherapy

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Introduction and Objective: Teplizumab (anti-CD3 antibody) is the first FDA-approved therapy to delay the onset of type 1 diabetes (T1D) and prolong insulin independence. This treatment paves the path for early-intervention strategies to build long-standing, antigen-specific immune tolerance and further prevent T1D. We have previously demonstrated that rapamycin-loaded polymersome nanoparticles (rPS) induce antigen-specific tolerance towards transplanted fully-MHC mismatched islets via a costimulation blockade in mice1. To assess if this strategy can protect native islets and tolerize autoantigens, rPS was benchmarked against anti-CD3 antibody in a spontaneous T1D mouse model. Methods: Rapamycin was encapsulated within nanocarriers fabricated from poly(ethylene) glycol and polypropylene sulfide block copolymer as previously described1. Randomized female nonobese diabetic (NOD) mice (n=16) were received subcutaneous rPS injections or intravenous anti-CD3 (clone 145-2C11) infusions at 8 weeks of age. Blood glucose and weight were routinely monitored in addition to markers of immune and metabolic function. Survival and statistical comparison between groups (Mantel-Cox and Two-Way ANOVA) was performed in GraphPad Prism 10. Results: rPS (6 doses at 0.5, 1, or 2 mg/kg) protected beta cell function and delayed the onset of T1D by at least 9 weeks relative to the untreated and anti-CD3-treated groups (p = 0.041). Only anti-CD3-treated mice developed lymphopenia (100%) and leukopenia (37.5%) during treatment. Insulin autoantibody (IAA) presence was more associated with T1D incidence for anti-CD3-treated mice, but the same trend was not observed in rPS-treated groups. Conclusion: rPS is a promising early-intervention therapy to delay the onset of T1D. rPS leverages antigen presenting cells to reprogram T cells for antigen-specific islet tolerance and can mitigate adverse events of chronic, nonspecific immunosuppression. 1. Burke JA, et al. Nat Nanotechnol. 2022;17(3):319-330. doi:10.1038/s41565-021-01048-2 Disclosure N.R. Klug: None. E.A. Scott: Other Relationship; AbbVie Inc. J.A. Burke: Consultant; SNC Therapeutics.
Uraemia and Cardiac Tamponade

Field: Medicine (Health Sciences)

MEDIALOURNL 447 suggests that the sooner it gets into the care of its adoptive parents the better.There is another truth that mothers could be told which might help to relieve their guilt.It is that their babies are in great demand, and that by surrendering their rights at birth they are performing a valuable public service and bringing happiness to childless couples.-Iam, etc., Southsea, Hants.
SHORT NOTICES

Field: Arts and Humanities (Social Sciences)

Journal Article SHORT NOTICES Get access PATRICK DURUSAUHigh Places in Cyberspace: A Guide to Biblical and Religious Studies, Classics, and Archaeological Resources on the Internet (Scholars Press Handbook Series). Scholars Press, Atlanta 1998 (2nd edition). Pp. 381-a. Price: $29.95 paperback. ISBN: 0-7885-0492-4. JOHN F. HEALEY JOHN F. HEALEY UNIVERSITY OF MANCHESTER Search for other works by this author on: Oxford Academic Google Scholar Journal of Semitic Studies, Volume XLVI, Issue 2, Autumn 2001, Pages 381-a–381, https://doi.org/10.1093/jss/XLVI.2.381-a Published: 01 October 2001
Two-step laser ionization schemes for in-gas laser ionization and spectroscopy of radioactive isotopes

Field: Physics and Astronomy (Physical Sciences)

The in-gas laser ionization and spectroscopy technique has been developed at the Leuven isotope separator on-line facility for the production and in-source laser spectroscopy studies of short-lived radioactive isotopes. In this article, results from a study to identify efficient optical schemes for the two-step resonance laser ionization of 18 elements are presented.
EUV tools: hydrogen gas purification and recovery strategies

Field: Chemical Engineering (Physical Sciences)

The technological challenges that have been overcome to make extreme ultraviolet lithography (EUV) a reality have been enormous1. This vacuum driven technology poses significant purity challenges for the gases employed for purging and cleaning the scanner EUV chamber and source. Hydrogen, nitrogen, argon and ultra-high purity compressed dry air (UHPCDA) are the most common gases utilized at the scanner and source level. Purity requirements are tighter than for previous technology node tools. In addition, specifically for hydrogen, EUV tool users are facing not only gas purity challenges but also the need for safe disposal of the hydrogen at the tool outlet. Recovery, reuse or recycling strategies could mitigate the disposal process and reduce the overall tool cost of operation. This paper will review the types of purification technologies that are currently available to generate high purity hydrogen suitable for EUV applications. Advantages and disadvantages of each purification technology will be presented. Guidelines on how to select the most appropriate technology for each application and experimental conditions will be presented. A discussion of the most common approaches utilized at the facility level to operate EUV tools along with possible hydrogen recovery strategies will also be reported.
Thermally stimulated relaxation in NaF X-irradiated at room temperature

Field: Physics and Astronomy (Physical Sciences)

The thermally stimulated processes in NaF X-irradiated at room temperature are studied. Three processes are observed whose relative weight depends on the F-coloring stage: (1) electron release; this causes glow peaks to appear at 75 and 115°C, as a result, M+ centers are annealed out; (2) interstitial fluorine release from different traps and subsequent recombination with F-centers and F-aggregate centers, it causes glow peaks at 70, 130, 200, 240, and 280°C; (3) F-center migration causing their annealing by recombination with interstitials or the formation of F-aggregate centers. Nous avons étudié les processus stimulés thermiquement dans le NaF irradié aux rayons X à température ambiante. Trois processus ont été observés dependant de l'étape de coloration: (1) Libération d'électrons qui correspond aux pics luminescents observés à 75 et 115°C. Le résultat principal est la disparition des centres M+. (2) Libération des atomes interstitiels de fluorine provenant de pièges différents avec la postérieure recombinaison des centres F et de ses agrégats. Il correspond aux pics luminescents à 70, 130, 200, 240 et 280°C. (3) Migration des centres F pour se recombiner avec des atomes interstitiels ou pour former des centres agrégats.
Antithrombin therapy for severe preeclampsia: results of a double-blind, randomized, placebo-controlled trial. BI51.017 Study Group.

Field: Medicine (Health Sciences)

A double-blind, randomized, placebo-controlled trial was conducted to evaluate whether treatment with Antithrombin (AT) concentrates improved the clinical and perinatal outcome in patients with severe preeclampsia. Severe preeclamptic patients (24 to 35 weeks of gestation. Gestosis Index (GI) > or = 6 points) were randomized into two groups: 66 received AT and 67 received placebo. There were no statistical differences in the clinical profiles of the two groups. Study drugs were given intravenously once daily for 7 consecutive days. Maternal symptoms were evaluated from the difference of GI between before and after treatment, and fetal findings were evaluated from the changes of the biophysical profile score and the estimated fetal weight gain. Improvement was significantly greater in the AT group for both the GI (p = 0.020) and the estimated fetal weight gain (p = 0.029). The improvement of coagulation parameters was also evaluated. The D-dimer levels increased significantly in the placebo group (p = 0.026), but did not change in the AT group. Gestation was significantly prolonged (p = 0.007), and the number of low-birth weight infants was significantly smaller (p = 0.011) in the AT group. No adverse events related to AT were observed. It is revealed that AT concentrate therapy for preeclampsia is effective and safe, leading to an improved perinatal outcome.
Understanding Metagaming Mechanics in Interactive Storytelling

Field: Computer Science (Physical Sciences)

Metagaming, any action taken outside of a game world with the goal of aiding gameplay, has traditionally been discouraged within the genre of interactive story-telling because it breaks immersion. With the development of new forms of narrative games, there are more and more games that use metagaming-based mechanics within the design of the game. However, we currently do not understand the impact that these mechanics have on the player's narrative experience. This project involved the analysis of existing games that utilize a specific metagaming-based mechanic, rewind/redo, in order to develop a formal vocabulary. This vocabulary informed the design of three versions of an experimental game. This game, titled Rough Draft, was used in a formal research study that gathered empirical data through qualitative and quantitative results analysis as well as observations of gameplay practices. Significant findings include qualitative response trends that support our theoretical claims as well as results that provide additional insights into best design practices for interactive story games that utilize a rewind/redo mechanic.
CASE OF MYATONIA CONGENITA TREATED SUCCESSFULLY WITH ADRENAL CORTEX (ESCHATIN)

Field: Medicine (Health Sciences)

Case Reports1 February 1939CASE OF MYATONIA CONGENITA TREATED SUCCESSFULLY WITH ADRENAL CORTEX (ESCHATIN)MAX H. WEINBERG, F.A.C.P., M.D.MAX H. WEINBERG, F.A.C.P., M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-12-8-1382 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptMyatonia congenitahas attracted a great deal of attention, in spite of its comparative rarity, ever since the condition was first described by Oppenheim in 1900. In 1917 Reuben1could gather from the literature only 130 cases and reported on six of his own, the highest number reported by one observer. The majority of the reports deal with but one or two cases. Most of the reports are concerned only with description of the disease and the central point of the discussion is, usually, whether it is a separate entity or merely another manifestation of the Werdnig-Hoffman type of infantile...Bibliography1. REUBEN MS: Amyotonia congenita of Oppenheim; A report of six cases with a full review of the literature, Arch. Int. Med., 1917, v, 657-700. CrossrefGoogle Scholar2. KERLEYBLANCHARD CGK: Amyotonia congenita: report of two cases, Arch. Pediat., 1927, xliv, 26-31. Google Scholar3. SHUMAN JR: Amyotonia congenita: report of two cases, Arch. Pediat., 1926, xliii, 225-234. Google Scholar4. WOLF A: Quinine: an effective form of treatment for myotonia, Arch. Neurol. and Psychiat., 1936, xxxvi, 382-383. CrossrefGoogle Scholar5. SMITH WA: Quinine treatment of myotonia congenita, Jr. Am. Med. Assoc., 1937, cviii, 43. CrossrefGoogle Scholar6. KENNEDYWOLF FA: Experiments with quinine and prostigmin in treatment of myotonia and myasthenia, Arch. Neurol. and Psychiat., 1937, xxxvii, 68-74. CrossrefGoogle Scholar7. ALBANESE A: Lassezza ed incongruezze articolari nella miatonia congenita di Oppenheim: tentativi e possibilita di cure orthppediche, Pediat., 1936, xliv, 601-621. Google Scholar8. RICHTERLEVINE KPM: Sympathectomy in man; its effect on the electrical resistance of the skin, Arch. Neurol. and Psychiat., 1937, xxxviii, 756-760. CrossrefGoogle Scholar9. BING R: A textbook of nervous diseases, Rebman Co., p. 362. Google Scholar10. HOWELL WH: A text book of physiology, 1910, Saunders, Philadelphia, p. 843. Google Scholar11. THADDEA S: Infection and adrenal cortex, Klin. Wchnschr., 1935, xiv, 1275. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Pittsburgh, Pennsylvania*Received for publication January 26, 1938.From the Neurological Service of the Western Pennsylvania Hospital. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byContributions to the Symptomatology of Amyotonia Congenita (Infantile Spinal Muscular Atrophy). 1 February 1939Volume 12, Issue 8Page: 1382-1385KeywordsAdrenal cortex ePublished: 1 December 2008 Issue Published: 1 February 1939 PDF downloadLoading ...
Effectiveness of a Video-Assisted Teaching Program on Knowledge Regarding Early Identification and Management of Polycystic Ovarian Disease (PCOD) Among Young Adults at Sanjay Gandhi College of Nursing, Bangalore

Field: Health Professions (Health Sciences)

Polycystic Ovarian Disease (PCOD) is an extremely common endocrine disorder among women of reproductive age. It is associated with hormonal imbalances, leading to menstrual irregularities, infertility, and metabolic complications. Early detection and appropriate management of Poly Cystic Ovarian Disease can help prevent long-term health consequences such as diabetes, cardiovascular disease and infertility. This study attempted to measure the effectiveness of a Video-Assisted Teaching Program on knowledge related to early identification and management of PCOD among young adults at Sanjay Gandhi College of Nursing, Bangalore. A pre-experimental one-group pre-test and post-test design was used for the study. Simple random sampling was used, and a total of 50 young adults were selected. The knowledge questionnaire was structured and had comprehensive information regarding the causes, symptoms, diagnosis, and management strategies of Poly Cystic Ovarian Disease (PCOD). Data were collected before and after administering the Video Assisted Teaching Program. The results of the pre-test revealed that 94% of the participants had inadequate knowledge with a mean score of 6.34 (31.7%). After the intervention, the post-test results had a significant improvement in knowledge, with 44% achieving adequate knowledge and a mean score of 15.3 (76.5%). Statistical analysis using a paired t-test indicated that the Video Assisted Teaching Program was highly effective, with a t-value of 2.42, significant at p < 0.05. In addition, significant associations were found between the pre-test knowledge scores and selected socio-demographic variables, such as year of study, socio-economic status, and parental education. The results indicate that video-assisted teaching is an effective educational tool to raise the awareness and understanding of Poly Cystic Ovarian Disease (PCOD) among young adults. The study emphasizes the need for incorporating innovative educational strategies like VATP into nursing curricula to improve reproductive health literacy and empower individuals to adopt preventive and management measures effectively. Future studies could explore similar interventions on larger, more diverse populations.