jimnoneill/paper-to-field-training huggingface dataset:
Drug discrimination and drug stimulus generalization with anxiolytics

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Abstract Work with lorazepam in two‐lever food‐maintained drug discrimination procedures with baboons and rats found greater specificity in the generalization profile when this drug was used as a training drug compared to studies with other benzodiazepines (BZ). That is, animals trained to discriminate lorazepam have not reliably made the drug response in tests with barbiturates, although animals trained to discriminate diazepam, chlordiazepoxide, triazolam, oxazepam, and sometimes midazolam commonly have done so. Characterization of the discriminative stimulus effects of lorazepam has included manipulation of species, training dose, and route of administration; drug interaction studies; and tests with a variety of anxiolytics. The time course of the discriminative stimulus effects of lorazepam and other drugs also has been studied using a multiple session procedure in baboons. Some of these results have provided information relevant to the extent to which intermediate levels of the drug response in test sessions at doses that do not reduce response rates may meaningfully reflect threshold or partial drug stimulus effects.
Street Fighter III: 3rd Strike: (SE) Z3rog vs(GB) Redemption101 - 2020-09-01 20:15:26

Field: Computer Science (Physical Sciences)

(SE) Z3rog vs (GB) Redemption101 - 2020-09-01 20:15:26 Fightcade replay id: 1598991326268-5181For more videos check out: https://fightcadevids.com
Internationaler Klimaschutz mithilfe nationaler Verfas- sungsgerichte? Erkenntnisse aus dem Klimabeschluss des BVerfG

Field: Social Sciences (Social Sciences)

Domestic Courts as Guarantors of International Climate Protection? Insights from the Climate Decision of the German Federal Constitutional Court The international climate protection regime depends on a willingness of states to cooperate that it cannot guarantee itself. Worldwide, there is a divergence between the need for ecological action and the political will to bring about the necessary changes in the national and international economy. As a result, climate lawsuits in domestic courts aimed at persuading policy-makers to make greater climate protection efforts have increased. Like the Dutch Hoge Raad and the Irish Supreme Court, the German Federal Constitutional Court has defined its function for global climate protection in its climate decision. This consists primarily of strengthening international co-operation in the area of climate protection. To this end, the Court gives Article 20a of the Basic Law an international dimension and calls for political cooperation for climate protection at the international level. The Court closely links constitutional law to the Paris Agreement and places itself at the service of enforcing the internationally agreed regime. The decision is motivated by the insight that climate protection cannot be achieved by a democratic sovereign alone, but only through concerted action at the international level.
BEHAVIOR OF PREGNANT WOMEN IN RELATION TO ADHESION TO AND PERIOD OF COMPLIANCE WITH A WATER AEROBICS PROGRAM

Field: Health Professions (Health Sciences)

Water aerobics is recommended to pregnant women, but there are few studies analyzing adhesion or compliance of pregnant women with exercises. The objective of this study is verifying and characterizing the behavior of pregnant women who practice water aerobics, in regards to the average gestational age upon adhesion (GAA) to the program, average period of compliance (PC) with it and the average gestational age upon interruption (GAI) of the program. A survey was conducted through the database of a gym in Porto Alegre, between 2001 and 2005, with 308 pregnant women, from classes A and B + , average age 32.14 ± 4.01 years. The Shapiro-Wilk test for normality and descriptive statistics was utilized in order to analyze measures of central tendency, using the statistical package SPSS, version 11.0. The results in gestational weeks (GW) showed that the GAA was 18.71 ± 5.62 (GW), the PC was 14.85 ± 7.09 (GW) and the GAI was 32.76 ± 4.01 (GW). Only 19.15% (59) of the pregnant women were exercising prior to adhering to the program, and the 80.85% who did not practice any physical activity regularly, started to practice water aerobics after they got pregnant. Most of the pregnant women (91.88%) waited until the end of the first trimester to adhere to the water aerobics program; most of them (76.29%) exercised during the second semester; and some (36.7%) went on practicing water aerobics after the 37 th week.
AAHS MEETING ARTICLE Early Clinical Outcomes with the Use of Decellularized Nerve Allograft for Repair of Sensory Defects Within the Hand

Field: Medicine (Health Sciences)

Abstract Nerve conduits have become an established option for repair of sensory deficits of up to 2 cm. More recently, decellularized nerve allograft has also been advocated as an option for nerve repair; however, no clinical studies have examined its efficacy for the treatment of sensory nerve defects. The aim of this study was to examine our early experience with the use of decellularized nerve allograft for repair of segmental nerve defects within the hand and fingers. From July 2007 to March 2008, seven patients who had ten nerve gaps were treated surgically using decellularized nerve allograft. Eight digital and two dorsal sensory nerves were repaired. The etiologies of the nerve defects were traumatic nerve transection in eight defects and neuroma resection and reconstruction in two defects. All of the affected nerves were pure sensory fibers.
The Current Situation in South Africa: A Sociological Perspective

Field: Social Sciences (Social Sciences)

The destruction of the state, the end of law, the dissolution of society, in which terms we can sum up the political situation today, what are these if not the end of the bourgeoisie as a class capable of guaranteeing order, of creating and keeping alive a state?Antonio Gramsci, quoted inJ. Joll, Antonio Gramsci 77(1977).Oppression, it has been said, breeds resistance and struggle. This is a basic law of human development from time immemorial. Like everybody else, the oppressed and exploited peoples of South Africa yearn for and dream of freedom and justice. Though the intensity of their struggle ebbs and flows, crucial junctures have occurred during which years are the equivalent of decades in terms of the intensity of their resistance. During these critical periods, illusions, which otherwise could linger and foster acquiescence, die. It is this state of affairs that has existed since September 1984 when the South African regime moved its troops into the black townships in an attempt to crush popular resistance to apartheid. Eight months later, having failed to do so, the South African government declared a state of emergency on July 21, 1985. Since then, with the exception of a brief period in early 1986, the country has been under continuous rule by emergency power. The powers themselves have been expanded and made more draconian as the regime attempted not only to suppress resistance but to destroy alternative structures organized by the resistance.
SH1910440.08FU

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
Risk of emergency department use among community-dwelling older adults: a review of risk factors and screening methods

Field: Health Professions (Health Sciences)

Growing use of emergency departments (EDs) among community-dwelling older adults represents a challenge for the entire health system and a potential opportunity for improved identification and management among community healthcare providers. Studies have examined risk factors for ED visits among samples of noninstitutionalized older adults. They suggest that need for care characteristics are robust risk factors for ED use. Six screening tools have been developed or validated to predict ED utilization among community-dwelling older adults. Some evidence suggests that risk screening tools are useful to stratify patients into meaningful risk gradients. Future empirical studies should employ a comprehensive set of potential risk factors and utilize contemporary risk modeling methods to improve existing knowledge and risk screeners.
Magna Carta and the Responsible Ministry

Field: Arts and Humanities (Social Sciences)

Journal Article Magna Carta and the Responsible Ministry Get access George Burton Adams George Burton Adams Search for other works by this author on: Oxford Academic Google Scholar The American Historical Review, Volume 20, Issue 4, July 1915, Pages 744–760, https://doi.org/10.1086/ahr/20.4.744 Published: 01 July 1915
Illumination invariance and shadow compensation on hyperspectral images

Field: Computer Science (Physical Sciences)

To obtain intrinsic reflectance of the scene by hyperspectral imaging systems has been a scientific and engineering challenge. Factors such as illumination variations, atmospheric effects and viewing geometries are common artefacts which modulate the way of light reflections from the object into the sensor and that they are needed to be corrected. Some of these factors induce highly scattered and diffuse irradiance which can artificially modify the intrinsic spectral reflectance of the surface, such as that in the shadows. This research is attempted to compensate the shadows in the hyperspectral imagery. In this study, three methods known as the Diffuse Irradiance Compensation (DIC), Linear Regression (LR) and spectro-polarimetry technique (SP) have been proposed to compensate the shadow effect. These methods have various degrees of shadow compensation capabilities, and their pros and cons are elucidated within the context of their classification performances over several data sets recorded within and outside of the laboratory. The spectro-polarimetry (SP) technique has been found to be the most versatile and powerful method for shadow compensation, and it has achieved over 90% of classification accuracy for the scenes with ~30% of shadow areas.
Study on the Determination of Flavor Value of Rice Based on Grid Iterative Search Swarm Optimization Support Vector Machine Model and Hyperspectral Imaging

Field: Agricultural and Biological Sciences (Life Sciences)

In the field of rice processing and cultivation, it is crucial to adopt efficient, rapid and user-friendly techniques to detect the flavor values of various rice varieties. The conventional methods for flavor value assessment mainly rely on chemical analysis and technical evaluation, which not only deplete the rice resources but also incur significant time and labor costs. In this study, hyperspectral imaging technology was utilized in combination with an improved Particle Swarm Optimization Support Vector Machine (PSO-SVM) algorithm, i.e., the Grid Iterative Search Particle Swarm Optimization Support Vector Machine (GISPSO-SVM) algorithm, introducing a new non-destructive technique to determine the flavor value of rice. The method captures the hyperspectral feature data of different rice varieties through image acquisition, preprocessing and feature extraction, and then uses these features to train a model using an optimized machine learning algorithm. The results show that the introduction of GIS algorithms in a PSO-optimized SVM is very effective and can improve the parameter finding ability. In terms of flavor value prediction accuracy, the Principal Component Analysis (PCA) combined with the GISPSO-SVM algorithm achieved 96% accuracy, which was higher than the 93% of the Competitive Adaptive Weighted Sampling (CARS) algorithm. And the introduction of the GIS algorithm in different feature selection can improve the accuracy to different degrees. This novel approach helps to evaluate the flavor values of new rice varieties non-destructively and provides a new perspective for future rice flavor value detection methods.
Morphological Classification of Echinochloa Species Collected in Rice Paddy Fields of California, U.S.

Field: Agricultural and Biological Sciences (Life Sciences)

This experiment was conducted to obtain basic information on the identification of weedy Echinochloa species in California(USA) rice fields by analyzing several morphological characteristics at two different growth stages. Both herbicide-susceptible and -resistant biotypes including E. oryzicola(Vasing.) Vasing., (late watergrass, E. phyllopogon(Stapf) Koss), E. crus-galli (L.) P. Beauv. (barnyardgrass), and E. oryzoides(Ard.) Fritsch(early watergrass) were evaluated. E. crus-galli and E. oryzoides had similar growth habit, height, and leaf characteristics at the seedling stage, however E. oryzicola was classified only by base culm diameter, leaf width, and leaf angle. Distinct differences among Echinochloa spp. were observed in morphological characteristics of the late growth stage. E. oryzicola was distinguished by increased plant height, later heading date, awnless spikelets, and larger length of empty glumes compared with the other two species. Resistant biotypes of E. oryzicola were separated from susceptible biotypes by earlier and more uniform heading date and shorter culm height, but no differences were measured between herbicide susceptible and resistant biotypes of the other two species. These results indicate that E. oryzicola can be distinguished from similar weedy Echinochloa species in the seedling stage and that herbicide resistant and susceptible biotypes of Echinochloa oryzicola are morphologically different
Microbiome and PCOS: State-of-Art and Future Aspects

Field: Medicine (Health Sciences)

Polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disease. The hypothesis that alterations in the microbiome are involved in the genesis of PCOS has been postulated. Aim of this review is to summarize the available literature data about the relationship between microbiome and PCOS. A search on PubMed and Medline databases was performed from inception to November 20Most of evidence has focused on the connection of intestinal bacteria with sex hormones and insulin-resistance: while in the first case, a relationship with hyperandrogenism has been described, although it is still unclear, in the second one, chronic low-grade inflammation by activating the immune system, with increased production of proinflammatory cytokines which interfere with insulin receptor function, causing IR (Insulin Resistance)/hyperinsulinemia has been described, as well as the role of gastrointestinal hormones like Ghrelin and peptide YY (PYY), bile acids, interleukin-22 and Bacteroides vulgatus have been highlighted. The lower genital tract microbiome would be affected by changes in PCOS patients too. The therapeutic opportunities include probiotic, prebiotics and synbiotics, as well as fecal microbiota transplantation and the use of IL-22, to date only in animal models, as a possible future drug. Current evidence has shown the involvement of the gut microbiome in PCOS, seen how humanized mice receiving a fecal transplant from women with PCOS develop ovarian dysfunction, immune changes and insulin resistance and how it is capable of disrupting the secondary bile acid biosynthesis. A future therapeutic approach for PCOS may involve the human administration of IL-22 and bile acid glycodeoxycholic acid.
Spatial-Temporal Pattern of Land Use and SDG15 Assessment in the Bohai Rim Region Based on GEE and RF Algorithms

Field: Environmental Science (Physical Sciences)

The United Nations has proposed Sustainable Development Goal 15 (SDG15), which emphasizes the importance of sustainable land development. This study aims to use remote sensing data to build a spectral index feature dataset based on Google Earth Engine (GEE) platform, dig deep spectral features of ground objects, and use a random forest (RF) algorithm to extract land use type distribution data in the Bohai Rim region from 2000 to 2020. Meanwhile, combined with a land use transfer map and landscape pattern index, the spatio-temporal pattern of land use was quantitatively analyzed. Finally, the sustainable development level of land was evaluated quantitatively from three aspects: forest resource sustainability, wetland resource sustainability, and land system sustainability. The results show that the overall accuracy and kappa coefficient of land use classification achieved by GEE and the RF algorithm were 0.94 and 0.92, respectively. From 2000 to 2020, the main land use type in the study area was cropland, accounting for 33% of the total, and the impervious has significantly expanded, increasing by 9588.01 km2, mainly from cropland, barren, and water. In relation to SDG15, forest resources exhibited poor stability, wetland resources demonstrated a steady recovery, SDG15.3.1 revealed that the problems of land degradation exist in various provinces and cities around the Bohai Sea, and the stability of the land system was poor between 2000 and 2020. This article can provide a valuable reference for land use management and ecological remediation in the Bohai Rim region.
Mitochondrial RNAs of myxomycetes terminate with non-encoded 3â² poly(U) tails

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

We examined the 3â² ends of edited RNAs from the myxomycetes Stemonitis flavogenita and Physarum polycephalum using a modified anchor PCR approach. Surprisingly, we found that poly(A) tails are missing from the cytochrome c oxidase subunit 1 mRNA (coI) from both species and the cytochrome c oxidase subunit 3 mRNA (cox3) from P.polycephalum. Instead, non-encoded poly(U) tails of varying length were discovered at the 3â² ends of these transcripts. These are the first described examples of 3â² poly(U) tails on mature mRNAs in any system.
Comparison of clinicopathological characteristics and outcomes between patients with late and early-onset systemic lupus erythematosus with lupus nephritis: A North African study

Field: Medicine (Health Sciences)

Objectives The aim of this study was to compare the clinicopathological characteristics and outcomes of lupus nephritis (LN) between late-onset and early-onset systemic lupus erythematosus (SLE) patients. Methods We reviewed the clinical, serological and histological characteristics of all patients with LN admitted to our nephrology unit between 2007 and 2024. Our patients were divided into two groups according to their age at diagnosis: Early-onset SLE (younger than 50 years) and late-onset SLE (50 years or older). Results A total of 231 patients were recruited, of whom 43 had late-onset SLE and 188 had early-onset SLE. The mean age at diagnosis of SLE was 58.36 ± 7.61 years in the late-onset SLE group and 29.23 ± 9.03 years in the early-onset SLE group. There was no difference in the time from SLE diagnosis to LN. Compared with early-onset group, late-onset group had a higher prevalence of discoid rash but a lower frequency of leukopenia. Late-onset patients had higher serum creatinine levels and lower prevalence of anti-SSA and anti-RNP antibodies. The frequency of class VI LN was statistically significantly higher in the late-onset group. The use of oral corticosteroids, hydroxychloroquine and immunosuppressive drugs was significantly lower in late-onset SLE patients than in early-onset SLE patients. The latter were significantly less likely to progress to chronic kidney disease. Conclusion Our results indicate that SLE patients have different clinical, serological and histological manifestations depending on the age at onset of the disease. Late-onset SLE patients are more likely to have rheumatoid arthritis at onset. They have more severe chronic renal lesions and a worse renal outcome.
Benzonitrile and acetonitrile complexes of ruthenium ammines

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBenzonitrile and acetonitrile complexes of ruthenium amminesRichard E. Clarke and Peter C. FordCite this: Inorg. Chem. 1970, 9, 2, 227–235Publication Date (Print):February 1, 1970Publication History Published online1 May 2002Published inissue 1 February 1970https://pubs.acs.org/doi/10.1021/ic50084a007https://doi.org/10.1021/ic50084a007research-articleACS PublicationsRequest reuse permissionsArticle Views928Altmetric-Citations114LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Award‐winning University Teachers’ Self‐efficacy Regarding Teaching

Field: Social Sciences (Social Sciences)

Abstract In 1989 and 1990 the University of Sydney announced awards for excellence in teaching to 12 members of its academic staff. This paper reports the results of an attempt to analyse two aspects of the award‐winners’ self‐efficacy regarding teaching: their perceived influence over their students’ learning, and their self‐rated competence on a set of teaching tasks. The award‐winners were found to score higher on both of these than comparison groups of less experienced university teachers, though the latter rated themselves higher on a research related teaching task.
Far Infrared and Raman Optical Study of CdInGaS4, CdIn2S4, HgInGaS4 and CdIn2S2Se2 Crystals

Field: Physics and Astronomy (Physical Sciences)

Abstract Raman and infrared reflectivity spectra of CdInGaS 4 , CdIn 2 G 4 , HgInGaS 4 , and CdIn 2 S 2 Se 2 crystals have been investigated. The fiindamental phonon parameters, the limiting dielectric constants ϵ 0 and ϵ∞ and the reflectivity spectrum contours have been calculated using classical dispersion relations.