jimnoneill/paper-to-field-training huggingface dataset:
Association Rule Mining and Prognostic Stratification of 2-Year Longevity in Octogenarians Undergoing Endovascular Therapy for Lower Extremity Arterial Disease: Observational Cohort Study (Preprint)

Field: Medicine (Health Sciences)

BACKGROUND

Two-year longevity is a crucial consideration in revascularization strategies for patients with symptomatic lower extremity arterial disease (LEAD). However, factors associated with 2-year longevity and risk stratification in octogenarians or nonagenarians have been underreported.

OBJECTIVE

This paper aims to investigate the associated variables and stratify the 2-year prognosis in older patients with LEAD.

METHODS

We performed logistic regression and association rule mining based on the Apriori algorithm to discover independent variables and validate their associations with 2-year longevity. Malnutrition, inflammation, and stroke factors were identified. C statistics and Kaplan-Meier analysis were used to assess the impact of different numbers of malnutrition, inflammation, and stroke factors on 2-year longevity.

RESULTS

We recruited a total of 232 octogenarians or nonagenarians (mean age 85 years, SD 4.2 years) treated with endovascular therapy. During the study period, 81 patients died, and 27 of those (33%) died from a cardiac origin within 2 years. Association rules analysis showed the interrelationships between 2-year longevity and the neutrophil-lymphocyte ratio (NLR) and nutritional status as determined by the Controlling Nutritional Status (CONUT) score or Geriatric Nutritional Risk Index (GNRI). The cut-off values of NLR, GNRI, and CONUT were ≥3.89, ≤90.3, and &gt;3, respectively. The C statistics for the predictive power for 2-year longevity were similar between the CONUT score and the GNRI-based models (0.773 vs 0.760; <i>P</i>=.57). The Kaplan-Meier analysis showed that 2-year longevity was worse as the number of malnutrition, inflammation, and stroke factors increased from 0 to 3 in both the GNRI-based model (92% vs 68% vs 46% vs 12%, respectively; <i>P</i>&lt;.001) and the CONUT score model (87% vs 75% vs 49% vs 10%, respectively; <i>P</i>&lt;.001). The hazard ratio between those with 3 factors and those without was 18.2 (95% CI 7.0-47.2; <i>P</i>&lt;.001) in the GNRI and 13.6 (95% CI 5.9-31.5; <i>P</i>&lt;.001) in the CONUT score model.

CONCLUSIONS

This study demonstrated the association and crucial role of malnutrition, inflammation, and stroke factors in assessing 2-year longevity in older patients with LEAD. Using this simple risk score might assist clinicians in selecting the appropriate treatment.
Association between Reproductive Factors and Type 2 Diabetes: A Cross-Sectional Study

Field: Medicine (Health Sciences)

(1) Introduction: The available studies on the association between type 2 diabetes mellitus (T2DM) and menopause report conflicting results. (2) Objective: This study aimed to investigate the association of menopausal status, age at menopause, and length of the reproductive period with T2DM. (3) Methods: This cross-sectional study is part of the ‘China Eastern Cohort Study’, which is a community-based cohort study. Multistage, stratified, clustered sampling was used to recruit the study participants in Shanghai, China. Age at menarche and menopause was recorded, and reproductive period was calculated. Weighted logistic regression was used to calculate the prevalence ratios (PRs) with 95% confidence intervals (CIs) of T2DM. Restricted cubic splines were used to assess the relationship between age at menopause, reproductive period, and T2DM. (4) Results: A total of 20,128 women were included. The prevalence of T2DM was 13.7%. Postmenopausal women exhibited a higher prevalence of T2DM than premenopausal women (p < 0.001) and an unfavorable metabolic profile, including higher body mass index, hypertension, and hyperlipidemia. A higher risk of T2DM was observed in postmenopausal women (PR2.12, 95%CI: 1.79–2.51, p < 0.001) compared with premenopausal women, independently of confounding factors. After adjustment for confounding factors, age at menopause and reproductive period were not significantly associated with T2DM. (5) Conclusions: Postmenopausal status is associated with T2DM, while menopausal age and reproductive period are not associated with T2DM. Menopausal status should be considered during T2DM screening.
Synthesis and evaluation of 1,2,4-triazole derivatives as antimicrobial, antifungal and anthelmintic agents

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Current research work is focused on incorporation of thiosemicarbazide, triazole in one framework and observed for antifungal, antibacterial and anthelmintic activities. Derivatives of 1,2,4-triazole-3-thiol are synthesized with thiosemicarbazide and semicarbazide as a starting material. Thiosemicarbazide are subjected to intermolecular cyclization in alkaline medium followed by acidification to give 1,2,4-triazole-3-thiol. Equimolar mixture of thiosemicarbazide and different consecutive acids are heated, fusion occurred to give different triazoles derivatives. The minimum inhibitory concentrations for synthesized compounds are in the range of 3.12-25 μg/mL.
Marginalisation in learning disability services: an exploration of the issues.

Field: Social Sciences (Social Sciences)

In order to understand the reasons for the rapid growth of\neugenics in late nineteenth century\nBritain and the U.S.A, one must first take account of the influence which the industrial and\nscientific revolution was exerting upon society (Giddens 1997,\nWorsley 1992). Pre-revolution\nsocieties had been based principally on agriculture, although there were some centres of trade\nand manufacture. These were typically large states, governed by kings or emperors (Giddens\n1997), with a simple form of social stratification, dividin\ng aristocratic groups from the rest of the\npopulace. Education too, was principally the realm of the aristocracy, with most of the peasantry\nbeing able to neither read nor write (Giddens 1997, Whelan 1995).\nIn the context of pre-industrial society, where the emphasis was on work rather\nthan on education, the problem of\nlearning disability was not a visible one. Multiply handi\ncapped children probably did not even\nsurvive pregnancy, and if they did, no health system exis\nted to support their lives (Worsley\n1992). Thus, it is likely that those learning disabled people\nwho did survive had, in present\nterms, mild to moderate degrees of disability, with littl\ne physical incapacitation. This supposition\nis supported by Plater’s (1535\n-1614) classification of mental disease, which identifies\nlearning\ndisability, at that time, solely in terms of mentis imbecilitas (mental weakness).
[Delayed Cardiac Tamponade After Blunt Chest Trauma].

Field: Medicine (Health Sciences)

Delayed cardiac tamponade following blunt chest trauma is a rare incident, and we provide a report including a literature review for further discussion. The patient is a 56-year-old male. He fell off a motorcycle and sustained contusions to the left side of his chest. He presented to our emergency department. His consciousness was clear and vital signs were normal. Computed tomography (CT) scan revealed multiple left rib fractures, left hemothorax, and left pulmonary contusion, but no pericardial effusion was detected. He returned home, and stayed at rest for a few days. He walked for 15 minutes on the third day after the injury, and he felt unwell and visited our emergency department again in a state of shock. Echocardiography and CT scan revealed significant amount of pericardial effusion, and emergency surgery was indicated. At surgery, bleeding site near the left ventricule (LV) apex was identified and hemostasis was achieved through median sternotomy. We should be careful of delayed cardiac tamponade after blunt chest trauma.
Simple Synthesis of Eudesmin through Oxidative Coupling of Carbanions and Reductive Catalytic Hydrogenation of Diketo Diester

Field: Chemistry (Physical Sciences)

Abstract A simple synthesis of eudesmin (1) is described. The key fragments were diol 13, dicarbethoxyethane 4, and diketo diester 5, which were prepared via reductive catalytic hydrogenation and oxidative intermolecular coupling of carbanions. This method is useful to generate the core skeleton of an endo–endo furofuran ring. Keywords: eudesminfurofuran lignansoxidative intermolecular couplingreductive catalytic hydrogenation Acknowledgments This work was supported by Korea Science and Engineering Foundation (KOSEF) (Grant No. RO5‐2004‐000‐10742–0).
P-011 Imaging and Histopathology of Thrombi in Acute Ischemic Stroke: Systematic Review and Meta-analysis

Field: Medicine (Health Sciences)

Background and purpose

There has been growing interest in the imaging and histopathology of retrieved thrombi after the introduction of mechanical thrombectomy for the treatment of acute ischemic stroke. We conducted a systematic review and meta-analysis of imaging and histological characteristics of thrombi in acute ischemic stroke.

Materials and methods

We identified all studies published between January 2005 and December 2015 that reported findings related to the histological and/or imaging characteristics of thrombi in patients with acute ischemic stroke secondary to large vessel occlusion. The five outcomes examined in this study were 1) the association between histological composition of thrombi and stroke etiology, 2) the association between thrombi histological composition and angiographic outcomes, 3) the association between imaging and histological characteristics of thrombi in stroke, 4) the association between imaging characteristics of thrombi and angiographic outcomes and 5) the association between imaging characteristics of thrombi and stroke etiology.

Results

There was no significant difference in the proportion of RBC rich thrombi between cardioembolic and large artery atherosclerosis etiologies (OR = 1.62, 95% CI = 0.1–28.0, P = 0.63). Patients with hyperdense artery sign had a higher odds of having RBC rich thrombi than those without a hyperdense artery sign on CT (OR = 9.0, 95% CI = 2.6–31.2, P < 0.01). Patients with a good angiographic outcome had a mean HU of 53.0 compared to a mean HU of 47.3 for patients with a poor angiographic outcome (MSD = 5.6, 95% CI = 1.1–10.0, P = 0.02). There was no association between imaging characteristics and stroke etiology (OR = 1.13, 95% CI = 0.32–4.00, P = 0.85).

Conclusions

Hyperdense artery sign is associated with RBC rich thrombi and improved recanalization rates. Further research is needed to determine the association between thrombi composition and stroke etiology as well as revascularization outcomes.

Disclosures

W. Brinjikji: None. S. Duffy: 5; C; Neuravi LTD. D. Kallmes: None.
ICONE11-36512 RESEARCHING ON KNOWLEDGE ARCHITECTURE OF DESIGN BY ANALYSIS BASED ON ASEME CODE

Field: Computer Science (Physical Sciences)

The quality of knowledge-based system's knowledge architecture is one of decisive factors of knowledge-based system's validity and rationality. For designing the ASME code knowledge based system, this paper presents a knowledge acquisition method which is extracting knowledge through document analysis consulted domain experts' knowledge. Then the paper describes knowledge architecture of design by analysis based on the related rules in ASME code. The knowledge of the knowledge architecture is divided into two categories : one is empirical knowledge, and another is ASME code knowledge. Applied as the basement of the knowledge architecture, a general procedural process of design by analysis that is met the engineering design requirements and designers' conventional mode is generalized and explained detailed in the paper. For the sake of improving inference efficiency and concurrent computation of KBS, a kind of knowledge Petri net (KPN) model is proposed and adopted in expressing the knowledge architecture. Furthermore, for validating and verifying of the empirical rules, five knowledge validation and verification theorems are given in the paper. Moreover the research production is applicable to design the knowledge architecture of ASME codes or other engineering standards.
Clinical Evidence for Critical Cardiac Care

Field: Medicine (Health Sciences)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Development of Percolative Structure in Piezoresistive Polyisoprene-Nanostructured Carbon Composite

Field: Materials Science (Physical Sciences)

Certain attention has been converted to polyisoprene-nanostructured carbon composites (PNCC) as prospective piezoresistive materials for use in pressure sensing applications or as a tactile element in robotics. Recent research approved that vulcanization process has an important role in process chain to obtain material with necessary mechano-electric properties. \nIn current article we present an original attempt to investigate the development of percolative electroconductive structure of PNCC during vulcanization. The “in situ” measurements of electric conductivity have been performed to evaluate the change of materials electric resistivity directly during the vulcanization process. Samples with different vulcanization times have been evaluated using high frequency AC measurements as well as SEM analysis on fractured surfaces. The dependence of conductance G and capacitance Cp on AC frequency for PNCC samples with different vulcanization times confirmed the development of conductive grid during vulcanization process. The results have been presented and evaluated to make certain conclusions.
Comparison of Yields of First-Generation Tobacco Hybrids with Those of Parent Plants

Field: Agricultural and Biological Sciences (Life Sciences)

Journal Article Comparison of Yields of First-Generation Tobacco Hybrids with Those of Parent Plants Get access True Houser True Houser Wooster, Ohio. Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Heredity, Volume os-7, Issue 1, January 1912, Pages 155–167, https://doi.org/10.1093/jhered/os-7.1.155 Published: 01 January 1912
Design of Ultra-Broadband RCS-Reduction Checkerboard Surface Using AMC Circuit Model

Field: Engineering (Physical Sciences)

A design procedure is introduced where a refined algorithm is developed and employed on single-band AMCs leading to a 10-dB RCS-reduction bandwidth of 80%. The AMC circuit model is utilized cleverly to reduce the substrate thickness while simultaneously increasing the bandwidth of AMC surfaces. Furthermore, dual-band AMC surfaces are synthesized and utilized in combination with single-band AMC surfaces to extend the 10-dB RCS-reduction bandwidth from 80% to about 99%.
Generalized tables of corrections to thermodynamic properties for nonpolar gases

Field: Chemistry (Physical Sciences)

Note presenting tables based on the Lennard-Jones 6-12 potential for nonpolar molecules to be used in the representation of second and third virial coefficients and equation-of-state corrections for enthalpy, entropy, specific heats at constant volume and at constant pressure, the ratio of specific heats, the isentropic expansion coefficient, and the velocity of sound.
Residual coding in ICHPPC: the size of the problem and its impact on research.

Field: Health Professions (Health Sciences)

In initial field trials of the International Classification of Health Problems in Primary Care (ICHPPC), the number of problems coded in residual (;other') categories was <5 per cent. Since then, there have been no published analyses of the residual category. Problems have been coded and computerized for over eight years at the Medical University of South Carolina Department of Family Medicine model practice. An analysis of that experience demonstrates that 14.3 per cent of the 85,000 problems were coded as residuals. Many classes or subclasses had >40 per cent coded as residuals. A residual as large as this is a major deterrent for research or practice analysis in a residency setting in anything more than a general category or descriptive manner. If many residuals also occur in other settings, this aspect of the code as well as the coding itself will need further study and improvement.
Integrated Science: An Interdisciplinary Approach for Junior College Teaching

Field: Arts and Humanities (Social Sciences)

Research Article| October 01 1966 Integrated Science: An Interdisciplinary Approach for Junior College Teaching Pauline Gratz Pauline Gratz Search for other works by this author on: This Site PubMed Google Scholar The American Biology Teacher (1966) 28 (8): 627–631. https://doi.org/10.2307/4441449 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Pauline Gratz; Integrated Science: An Interdisciplinary Approach for Junior College Teaching. The American Biology Teacher 1 October 1966; 28 (8): 627–631. doi: https://doi.org/10.2307/4441449 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentThe American Biology Teacher Search This content is only available via PDF. Copyright 1966 The National Association of Biology Teachers Article PDF first page preview Close Modal You do not currently have access to this content.
Brief Analysis on the Views of Life and Death in Shibi(the most authoritative and knowledgeable man) Classics of the Qiang Nationality

Field: Arts and Humanities (Social Sciences)

Views of life and death in Shibi's classics of the Qiang nationality are tainted with a strong religious colour,which is manifested in an open view of life and death by observing people,the exploration of the causes of life and death,and the pursuit of longevity and struggle against death.The views are the embodiment of the unique cultural characteristics of national funeral of the Qiang nationality.
Ossicles of the stomach wall of Ophiuroidea and their taxonomic significance II

Field: Agricultural and Biological Sciences (Life Sciences)

Fifteen types of ossicles in the stomach wall of Ophiuroidea were observed by SEM. Ossicle analysis seems to be useful for the identification of species belonging to the genus Ophioderma. The present result supports to Devaney's taxonomic system of the genus Ophiocoma.
Anti-HLA antibodies and kidney allograft outcomes in recipients with donor bone marrow cell infusion.

Field: Medicine (Health Sciences)

Our findings reveal an association between pre- and post-transplant anti-HLA antibodies, and ARE and also early allograft dysfunction. It suggests that lower incidence of ARE, undetectable DSA, lower titer of antibodies concomitant with a decrease in serum creatinine level, better allograft function and lower percentages of PRA in DBMI patients, could be the probable manifestations of partial hypo-responsiveness against allografts.
John Hart Ely in the Mexican Supreme Court

Field: Arts and Humanities (Social Sciences)

Abstract In this article, I reflect upon the influence that John Hart Ely’s book Democracy and Distrust can have on our discussions about the Mexican Supreme Court. For that purpose, I distinguish the Mexican Court’s role under authoritarian rule and in democracy. In the former era, Ely’s theory would not have even been considered. In the latter, the Court has adopted a substantive conception of democracy and judicial review based on authors such as Ronald Dworkin, Robert Alexy, and Luigi Ferrajoli. Moreover, in the last twelve years, the Court has developed a human rights agenda. During this time, it has interpreted human rights and economic liberties, issuing rulings that are similar to those that preoccupied Ely forty years ago (Lochner v. New York or Roe v. Wade). In this regard, Ely’s theory is useful to think about the current situation of constitutional justice in Mexico, even if we do not embrace his proposal that limits the role of the Court to procedural issues. In a country such as Mexico, where the reality of our democracy is much feebler and deep economic and social inequalities predominate, the Court is compelled to play a transformative role.
SURGICAL MANAGEMENT OF LIMITATION OF MOTION DUE TO CONTRACTURE OF GLUTEUS MAXIMUS

Field: Medicine (Health Sciences)

The congenital or acquired contracture of gluteus maximus is relatively rare, and its clinical feature of chronic lower back pain and extension contracture of the hip joint had been confused with herniations of lumbar disc disease or sequelae of cerebral palsy. The authors successfully treated these contracture of gluteus maximus, so report these cases and results. 9 patients suffering from Difficulty in squatting position or gait disturbance were surgically treated in our department from 1979 to 2000. There were eight men and a woman, mean age was 17.3 years old, and seven patients were bilateral. Four patients revealed past medical history of multiple intramuscular injection at gluteal region, but five patients revealed unremarkable history. Preoperative mean further flexion, internal rotation and external rotation of hip joint were 42°, 15°, and −5°. These patients revealed specific features of frog leg position in squatting position. Intraoperatively, the authors released the fibrotic band of the gluteus maximus, the short external rotators, the gluteal attachment of the iliotibial band and the joint capsule. After anesthesiologic recovery, active and passive joint motion exercise of flexion and rotation was started to prevent recurrence of contracture. Postoperatively, mean further flexion of hip joint were increased to 105°, and no Difficulty in sitting or squatting position, but slight limitation in rotation was remained. In follow up visit, no decrease of articular motion were observed. Conclusively, severe limitation of joint motion due to contracture of gluteus maximus can be successfully treated with surgical maneuver accompanied with postoperative aggressive physical therapy.
On the history of growing ivies in Nikitsky botanical garden

Field: Agricultural and Biological Sciences (Life Sciences)

Problems of the history of cultivation of taxa and culta of the genus Hedera in Nikitsky botanical garden are analyzed. Data on the genus Hedera is revealed to be incomplete and contradictory or absent at all on the various stage of the Garden history. The most important impetus to ivy collection development was given by N.A. Hartwiss and L.I. Uleiskaya. Author shows unknown pages of the history: he revealed some specimens of ivy cultivars that were grown here up to the end of 1920-s, and several ivy cultivars were discovered as relicts of cultivation in the arboretum of Nikitsky garden and also in the former Hartwiss’ estate in Artek.