jimnoneill/paper-to-field-training huggingface dataset:
[Effectiveness of oral vitamin B12 therapy for pernicious anemia and vitamin B12 deficiency anemia].

Field: Medicine (Health Sciences)

We investigated the efficacy of oral vitamin B12 (B12) therapy in patients with B12-deficiency anemia. Between June 1994 and June 2000, 17 patients, who were diagnosed as having B12-deficiency anemia and gave their informed consent, were enrolled in this study. Of these patients, 7 were further treated with a maintenance dose of methylcobalamin (1,500 micrograms daily for 7 days every 1-3 months). Correction of hematological and neurological abnormalities was prompt. The hemoglobin level and serum concentration of B12 were normalized within two months after starting the treatment. Recovery from neurological disturbance was observed within one month. To maintain a normal serum concentration of B12, a 7-day regime of administration was needed every month in 3 patients, every 2 months in 3 patients, and every 3 months in 1 patient. These results demonstrate the effectiveness of oral cobalamin therapy, and also that oral intermittent therapy is useful for maintaining a normal serum B12 concentration. Oral cobalamin therapy might be as effective as conventional injection therapy, and useful for long-term treatment.
Neurological toxicity related to pefloxacin

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Journal Article Neurological toxicity related to pefloxacin Get access JEAN-CHRISTOPHE LUCET, JEAN-CHRISTOPHE LUCET Centre Henri Becquerel and Hôpital Charles NicolleRouen, France Search for other works by this author on: Oxford Academic PubMed Google Scholar HERVÉ TILLY, HERVÉ TILLY Centre Henri Becquerel and Hôpital Charles NicolleRouen, France Correspondence address: Dr Hervé Tilly, Centre Henri Becquerel, 76038 Rouen, France Search for other works by this author on: Oxford Academic PubMed Google Scholar GUY LEREBOURS, GUY LEREBOURS Centre Henri Becquerel and Hôpital Charles NicolleRouen, France Search for other works by this author on: Oxford Academic PubMed Google Scholar JEAN-JACQUES GRES, JEAN-JACQUES GRES Centre Henri Becquerel and Hôpital Charles NicolleRouen, France Search for other works by this author on: Oxford Academic PubMed Google Scholar HUBERT PIGUET HUBERT PIGUET Centre Henri Becquerel and Hôpital Charles NicolleRouen, France Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Antimicrobial Chemotherapy, Volume 21, Issue 6, June 1988, Pages 811–812, https://doi.org/10.1093/jac/21.6.811 Published: 01 June 1988
Additional file 1 of Improved analysis of (e)CLIP data with RCRUNCH yields a compendium of RNA-binding protein binding sites and motifs

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Additional file 1: Figure S1. Simulation of a CLIP experiment. Figure S2. Agreements of peaks identified between individual ENCODE samples. Figure S3. Similarity of de novo predicted motifs of different RBPs. Figure S4. RCRUNCH results for all ENCODE eCLIP data currently available. Figure S5. Evaluation of the model used to identify enriched regions. Figure S6. Binding events spanning splice junctions. Figure S7. Motif enrichments as a function of the number of top peaks. Figure S8. RCRUNCH application to PAR-CLIP data.
Effect of Culture and Induction Conditions on Dormancy Period of Potato Microtuber

Field: Agricultural and Biological Sciences (Life Sciences)

The potato microtubers were induced in vitro by one-step method without replacing medium and adding exogenous hormones.The effects of photoperiod,light intensity and temperature at culture stage and illumination length at induction stage were studied on the microtuber dormancy period of three potato varieties 'Favorita','Atlantic' and 'Kexin 1'.The results showed that at culture stage,light intensity had no significant effect on microtuber dormancy period,but the prolonging of illumination time could increase the microtuber dormancy period steadily;high temperature shortened the microtuber dormancy period obviously.At induction stage,the microtubers induced in long darkness had long dormancy period.
Novel Sliding Mode Vibration Controller With Simple Model-Free Design and Compensation for Actuator’s Uncertainty

Field: Engineering (Physical Sciences)

This study proposes an active vibration control method with a simple design process without using a plant model. The proposed method is robust against the actuator's parameter uncertainty. To realize model-free control of the controlled object, a virtual structure represented by a single-degree-of-freedom system is inserted between the controlled object and the actuator. A controller, which compensates for the uncertainties of the actuator's parameters, is designed using the sliding mode control theory. By designing a controller using a model composed of the virtual structure and the actuator, model-free design can be easily performed with few design variables. After the virtual structure is introduced, the controller can be designed using the same process as a traditional model-based control theory. An advantage of the sliding mode control system is it can provide high robustness against the uncertainty in the actuator's parameters. The robustness to the actuator's uncertainty and vibration suppression performance of the proposed method are verified by controlling a two-degree-of-freedom time-varying system. Finally, the applicability of the proposed method to an actual mechanical system is confirmed by vibration control experiments.
AN ALGORITHM FOR SELECTING THE PARAMETERS OF A SUPERCAPACITOR AS PART OF AN ENERGY STORAGE SYSTEM OF AN ELECTRICAL COMPLEX IN CASE OF VOLTAGE DIPS

Field: Energy (Physical Sciences)

The operation of electrical complexes of industrial enterprises is often characterized by violations of electricity quality indicators, in particular, prolonged changes in voltage characteristics and random events described by strong and spontaneously occurring fluctuations in the shape of the supply voltage. In this article, special attention is paid to voltage dips that occur in the supply network of a liquefied natural gas plant and are the reason for the shutdown of a continuous technological process. The main cause of voltage failures for the selected object of study are atmospheric overvoltages and, as a result, short circuits on the side of external power supply. The paper considers the main methods of leveling voltage dips using both the software tools of the complex and the hardware. As a solution for this object, the installation of an energy storage system based on supercapacitors connected to a direct current link of an electric drive is proposed. The authors have developed a new approach to the selection of these drives, which is based on the revealed mathematical dependencies of the number of supercapacitor units on their nominal capacity and voltage, the influence of the configuration of the connection of the drives inside the system on its final performance, as well as the nominal parameters of the object under consideration and the characteristics of voltage dips. Based on the data obtained, an algorithm for determining a supercapacitor with the required nominal parameters that meet the criteria of technical and economic efficiency for the object under consideration has been formed. In order to achieve the universality of the written algorithm for selecting a storage system based on supercapacitors, experiments were conducted to identify similar mathematical dependencies at different voltage and power levels of electrical complexes.
Water Hammer Induced by a Line Break

Field: Engineering (Physical Sciences)

A sudden break of a pressurized and dead-ended water main induces water hammer and possibly column separation at the dead end. Because a line break is an energy venting and depressurizing event, one may not anticipate overpressures as a result of the break. The purpose of this paper is to show that a line break can generate excessive overpressures severe enough to cause damage. Through analysis and laboratory tests, we demonstrate that (1) if column separation does not occur at the dead end of the main line, the transient pressure in the main does not exceed the initial pressure in the main prior to the break; (2) if column separation occurs, the transient pressure in the main can exceed the initial pressure; and (3) damaging overpressure in the connected service lines may occur whether column separation occurs in the main or not.
Trauma‐Informed Psychosocial Screening and Care Planning: A Patient‐Centered Improvement Project in a Midwife Clinic

Field: Health Professions (Health Sciences)

Introduction Traumatic stress is associated with increases in preterm birth, low birth weight, and other perinatal complications. Yet the identification of patients with traumatic stress and intervention for traumatic stress prevention or treatment remain low. Locally in this university hospital‐based midwife clinic, a health records review found that trauma exposure was documented in 5% of patient records, and no records had a diagnosis of posttraumatic stress disorder (PTSD). This is lower than research‐based population estimates of 25% to 50% for trauma exposure and 8% for PTSD during pregnancy. The clinic staff did not screen for posttraumatic stress, and exposure screening was limited to intimate personal violence. Staff had not been trained in trauma‐informed care (TIC) as defined by the Substance Abuse and Mental Health Services Administration. The aim for this improvement project was to provide trauma screening and trauma‐related care planning, collectively referred to as trauma‐informed psychosocial care, to midwifery patients 85% of the time. Process Interventions were implemented over 4 plan‐do‐study‐act (PDSA) cycles. These included staff training in TIC; written screening at the new prenatal, third trimester, and postpartum visits; verbal broad inquiry at every visit; and bidirectional trauma‐specific care planning emphasizing patient and provider input into treatment choice. The clinic flow was changed to create privacy for patient‐staff interaction at every visit. Field notes and data were analyzed every 2 weeks and iterative changes applied. Outcomes Trauma disclosure increased from 5% to 30% and identification of PTSD from 0% to 7%. Bidirectional care plan documentation increased from 8% to 67%. Staff rated the workload as reasonable. Discussion Redesigning psychosocial screening to align with TIC principles increased the discovery of trauma to levels consistent with research‐based population estimates. Gains were made in bidirectional care planning. This project illustrates practical methods of implementing TIC principles.
Lung Tumor Cell Recruitment Assay

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

To investigate the molecular mechanisms governing tumor metastasis, various assays using the mouse as a model animal have been proposed. Here, we demonstrate a simple assay to evaluate tumor cell extravasation or micrometastasis. In this assay, tumor cells were injected through the tail vein, and after a short period, the lungs were dissected and digested to count the accumulated labeled tumor cells. This assay skips the initial step of primary tumor invasion into the blood vessel and facilitates the study of events in the distant organ where tumor metastasis occurs. The number of cells injected into the blood vessel can be optimized to observe a limited number of metastases. It has been reported that stromal cells in the distant organ contribute to metastasis. Thus, this assay could be a useful tool to explore potential therapeutic drugs or devices for prevention of tumor metastasis.
Case Series on Post Renal Transplant Fungal Infections of the Lung

Field: Medicine (Health Sciences)

Invasive fungal infections are a significant concern for solid organ transplant (SOT) patients, especially those who have undergone small bowel or lung transplants. Renal transplant recipients commonly develop fungal infections like candidiasis, aspergillosis, and cryptococcosis, contributing to post-transplant infections. This case series presents three cases of pulmonary fungal infections after renal transplantation: cryptococcosis, mucormycosis, and invasive pulmonary aspergillosis. The objective is to highlight challenges in diagnosing and managing invasive fungal infections in SOT recipients, emphasizing early diagnosis, timely treatment initiation, and optimized antifungal drug pharmacokinetics for successful outcomes. Aims and Objectives: Include emphasizing the importance of prompt diagnosis and treatment, optimizing antifungal drug pharmacokinetics, and highlighting the need for intensive antifungal therapy in SOT patients with fungal infections. Methods: The cases involve comprehensive clinical information, diagnostic procedures (imaging, endoscopy, biopsies, microscopy, culture, and serologic testing), and treatment approaches. Antifungal therapy was promptly initiated, even without laboratory confirmation, to ensure timely treatment. Antifungal drug pharmacokinetics were optimized to minimize nephrotoxicity in SOT patients. Results: Case 1 describes a middle-aged obese woman with respiratory symptoms diagnosed with cryptococcosis. Case 2 presents a young male kidney transplant recipient with mucormycosis. Case 3 involves a male patient with cough and hemoptysis diagnosed with invasive pulmonary aspergillosis. All cases received appropriate antifungal therapy, leading to symptom resolution and radiological improvement, although some patients had persistent radiological opacities. Discussion: Diagnosing invasive fungal infections in transplant patients remains challenging, relying on clinical presentation and supportive diagnostic procedures. Management requires a multidisciplinary approach involving antifungal therapy, surgical intervention (if applicable), and control of predisposing factors. Primary treatments included liposomal amphotericin B and voriconazole, considering combination therapy and newer antifungal agents. Early detection and prompt treatment initiation are crucial to reduce mortality rates, especially in disseminated disease. Conclusion: Invasive fungal infections present significant challenges in solid organ transplant recipients. Despite advancements in diagnostics and antifungal therapies, mortality and graft loss rates remain high, particularly in disseminated disease cases. Future research should integrate data from various sources to enhance understanding of fungal pathogenesis, host immune responses, and pharmacological aspects, aiming to develop more effective prevention and treatment strategies for fungal infections in transplant recipients.
A Comparative Study to Evaluate the Effect of Warm Mustard Oil vs Warm Mustard Oil with Camphor on Relief of Knee Joint Pain among Rural Women in Selected Areas of Puducherry

Field: Health Professions (Health Sciences)

Background:Osteoarthritis is a common arthropathy of the knee. In India, the prevalence of the disease in the adult rural population is estimated to be 5.8%. Aim:The main aim of the present study was to compare the effectiveness of warm mustard oil and warm mustard oil with camphor on reduction of knee joint pain among rural women in selected rural areas of Puducherry. Materials and Methods:A quasi-experimental study (two group pretest and posttest design) done among 60 rural women with knee joint pain. Data were collected using structured questionnaire and modified WOMAC scale. Data analysis was done using inferential and descriptive statistics. Results:Totally 60 rural women participated in the study. It was observed that majority of the samples were in the age group between 51-55years. Majority of the samples in both group I and group II had moderate level of pain. After warm mustard oil massage and warm mustard oil with camphor massage, the pain level had reduced to mild level in group I and group II respectively.The mean pretest values of pain score in both groups had significant difference during posttest measurement of mean pain score. The coefficient of variance analysis revealed that warm mustard oil with camphor massage reduced the pain level more significantly than warm mustard oil massage. Conclusion:Knee joint pain is an early symptom of osteoarthritis and it is the leading cause of disability in humans especially in women.Hence efforts like use of warm mustard oil or warm mustard oil with camphor massage which is easily accessible and cost effective methods to reduce the knee joint pain should be made by the community health nurse to bring down the prevalence of knee joint pain.
Strategi Peningkatan Kualitas Barista dan Bartender di Hotel Four Points By Sheraton Bali Seminyak

Field: Business, Management and Accounting (Social Sciences)

This study aims to find out: (1) knowing what characteristics possessed by a professional barista and bartender, (2) knowing the obstacles faced by a barista and bartender at work, (3) knowing the efforts that must be made in improving barista and bartender skills . The method used in this research is descriptive qualitative. Data collection techniques used were observation and interviews. The subjects of this study were baristas and bartenders at the Four Points Hotel by Sheraton Bali Seminyak. Saddle, the object of this study is the characteristics of baristas and bartenders. The results showed that there are some requirements that must be possessed by a professional barista and bartender to improve the quality of service including having basic knowledge of coffee, having the ability to understand and master drinks, attitude or attitude and good communication. And there are some obstacles faced by baristas and bartenders in their work, which are different flavors of coffee, problematic espresso mechine, lack of preparation and guest complaints. Strategies used to improve the skills of a barista and bartender include training and participating in competitions related to baristas and bartenders.
Composition Analysis of Calcium Ferrite in Iron Ore Sinters by EPMA Scanning Method

Field: Materials Science (Physical Sciences)

To investigate the association of calcium ferrites in iron are sinters with aenigmatites, composition analysis of sinters is carried out by applying EPMA scanning method. Most of the calcium ferrite in sinters has been classified to aenigmatites. The stability domain of SFCA is bound by the three lines of 4CaO·3SiO2-CaO·3(Al, Fe)2O3, CaO·SiO2-CaO·6(Al, Fe)2O3 and SiO2CaO·3(Al, Fe)2O3 in the pseudo (CaO+MgO)-SiO2-(Fe2O3 +Al2O3) system.
Intra-sentential context effects on the interpretation of logical metonymy

Field: Computer Science (Physical Sciences)

Verbs such as enjoy in the student enjoyed the book exhibit logical metonymy: enjoy is interpreted as enjoy reading.Theoretical work (Pustejovsky, 1991(Pustejovsky, , 1995) ) predicts that this interpretation can be influenced by intra-sentential context, e.g., by the subject of enjoy.In this article, we test this prediction using a completion experiment and find that the interpretation of a metonymic verb is influenced by the semantic role of its subject.We present a Bayesian model that accounts for the interpretation of logical metonymy and achieves a good fit on our experimental data.We show that the parameters of the model can be estimated from completion data or from corpus data.
Hierarchical generation of dynamic and nondeterministic quests in games

Field: Computer Science (Physical Sciences)

Quests are a fundamental storytelling mechanism used by computer role-playing games to engage players in the game's narrative. Although role-playing games have evolved in many different ways in the last years, their basic narrative structure is still based on static plots manually created by game designers. In this paper, we present a method for the generation of dynamic quests based on hierarchical task decomposition and planning under non-determinism. The proposed approach combines planning, execution, and monitoring to efficiently handle nondeterministic events and support quests with multiple endings that affect the game's narrative and create interactive and dynamic story plots. These plots are directly or indirectly affected by player's actions and decisions. Furthermore, this paper presents the concept of hierarchical quests.
Legal rights to academic freedom in Australian universities

Field: Social Sciences (Social Sciences)

Much has been written about academic freedom and the law in the United States. In Australia academics constantly talk about and assert their academic freedom, but they have been less inclined to write about it or analyse it from a legal perspective. This work aims to redress that imbalance. The thesis briefly overviews academic freedom throughout the years commencing with an examination of Ancient Greece, before surveying the United Kingdom and Europe, and then, in more depth, analysing academic freedom law in the United States. Australia does not have the benefit of speech rights contained in the First Amendment to the Constitution of the United States, nor does it have a long history of attempts at specific universities or nationally to define academic freedom or give express legal force, contractually or otherwise to it. Accordingly the search for academic freedom rights concentrated on the possibility that the academic employment contract may contain legal rights implied by custom and tradition or by business efficacy. This further required a study of the nature of Australian universities to ascertain whether academic freedom in those universities and for staff within them is a necessary element for the carrying out of university teaching and research functions. A second source of possible rights is in enterprise bargaining agreements, or in policy documentation in universities such as codes of conduct which may expressly confer legal rights to academic freedom. The thesis also describes the law relating to dismissal for serious misconduct, testing whether the exercise of a speech right in a university could give rise to dismissal or other penalty. Finally, the work examines dismissal processes in Australian universities to discover whether these confer adequate protection for academics who may have spoken out in ways that offend their universities or other segments of society.
Instagram Captions by Berlian College Students: A Blend of Indonesian and English Code-Mixing

Field: Arts and Humanities (Social Sciences)

This study delves into the vibrant phenomenon of code-mixing in Instagram captions created by students, exploring how they seamlessly blend Indonesian and English. This research provides fresh insights into bilingual expression in a digital context by focusing on the specific types of code-mixing used and the underlying factors driving its adoption. Using a descriptive qualitative approach, the study analyzed Instagram posts from Berlian Education Training College students aged 18 to 25, focusing on 11 participants with higher English proficiency. The data collection technique used in this study is the documentation technique. The researcher documented natural data obtained from utterances posted on Instagram. The findings reveal a distinct insertion pattern: English words are strategically placed at Indonesian sentences' beginning, middle, or end. Factors influencing this linguistic blend include bilingualism, social background, vocabulary range, context, and interaction dynamics. This research sheds light on how young bilingual speakers creatively navigate their linguistic repertoire to communicate and connect on social media.