jimnoneill/paper-to-field-training huggingface dataset:
Performance measurement and NPOs' effectiveness: does internal stakeholders' trust matter? Evidence from Palestine

Field: Business, Management and Accounting (Social Sciences)

Purpose This study proposes a model of the effect of financial and non-financial performance measures on nonprofit organizations’ (NPOs’) effectiveness where internal stakeholders' trust play an intervening role in the aforementioned relationships. Design/methodology/approach Data were collected from 218 employees working at the largest Palestinian NPOs. The perceptions of these employees were used to measure the variables, and structural equation modeling was used to examine the hypotheses. Findings Results suggest that the use of financial and non-financial performance measures was positively related to NPOs' effectiveness. Internal stakeholders' trust showed a significant mediating effect between the use of performance measures and NPOs' effectiveness. Practical implications This study may be of value for NPOs' managers due to the positive effects performance measurement (PM) can have on NPO effectiveness. Managers and boards should seek to enhance their internal stakeholders' trust to achieve higher levels of effectiveness. Originality/value This study has three main contributions. First, it is one of the very few papers which empirically examines the links between PM and NPOs' effectiveness, rather than providing conceptual lens. Second, the paper investigates the role of stakeholders' trust as a mediating mechanism in the proposed model, a topic that has been neglected by NPOs governance researchers. Finally, the study uses data from the Palestinian context, contributing to the PM literature by providing evidence on the relationship between performance measures and NPOs' effectiveness from a non-Western context.
A low-profile Hader-bar system for implant-supported overdentures with minimum vertical clearance.

Field: Dentistry (Health Sciences)

A method for treating a minimum vertical clearance maxillary overdenture patient is detailed. A low-profile, cemented, Hader bar with parallel guiding planes is used to stabilize a maxillary implant-supported overdenture. This system maximizes implant support while maintaining simple construction, ease of oral hygiene maintenance, good space for excellent esthetics, and allows enough acrylic bulk for long-term service.
“Intelligent Construction, Digital Modeling of the Future” Internet + BIM Service EPC Project——Take the Exhibition Center of National Cybersecurity Center for Education and Innovation Project as an Example

Field: Engineering (Physical Sciences)

Abstract This paper discusses the application of Internet and BIM technology to serve the construction mode of “PPP +EPC+ Fund” and management mode of “Executive Architect”. Taking the Exhibition Center of National Cybersecurity Center for Education and Innovation project as an example, relying on the CITIC Intelligent Construction Platform, BIM and digital technology such as cloud computing, big data, IOT, mobile Internet, chainblock etc., are used in the entire life cycle of the project, including design, procurement, construction and facility management. The data sharing and information management of the whole life cycle of the project are realized, which strongly supports the scientific construction and operation of the project.
ACTIONS OF SCORPION VENOM ON SKELETAL MUSCLE

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

A protein‐like constituent of scorpion venom produced effects on the skeletal muscle fibre resembling those of citrate, lack of calcium or veratrine. These effects could be diminished by the addition of calcium. They do not appear to be due to the formation of a non‐ionized complex with calcium.
Strategies and Tactics for External Corporate Venturing

Field: Business, Management and Accounting (Social Sciences)

OVERVIEW:By providing a window on emerging technologies, market opportunities, new business models, and distribution channels, corporate venturing can be an important source of technological innovation for corporations. However, effective implementation requires a clear view of the objectives, dedication to understanding the process, and discipline. There are two major tactics for external investing: invest in a venture capital fund, or invest directly in a start-up company, and the strategy a company chooses should be tied to its objectives. For example, best-of-class companies whose objective is to acquire a window on technology will invest in VC funds to gain access to their wider deal flow. One of the most challenging aspects of corporate venturing is finding the right people, and corporations must be willing to devote significant time and resources to working closely with their portfolio companies if they wish to gain satisfactory value from their external investments.
Screening of Phytochemicals from Curcuma Longa for their Inhibitory Activityon SARS-CoV-2: An In-Silico Study

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Introduction: Natural products or phytochemicals have always been useful as effective therapeutics providing the lead for rational drug discovery approaches in specific to anti-viral therapeutics. Methods: The ongoing pandemic caused by novel coronavirus has created a demand for effective therapeutics. Thus, to achieve the primary objective to search for effective anti-viral therapeutics, in silico screening of phytochemicals present in the extract of Curcuma longa (ex. Curcumin) has been planned. Results: The present work involves the evaluation of ADME properties and molecular docking studies. Conclusion: The application of rationalized drug discovery approaches to screen the diverse natural resources will speed up the anti-COVID drug discovery efforts and benefit the global community.
Agonists for neuropeptide Y receptor subtypes NPY-1 and NPY-2 have opposite actions on rat nodose neuron calcium currents

Field: Neuroscience (Life Sciences)

1. The whole-cell variation of the patch-clamp technique was used to study the effect of neuropeptide Y (NPY) and preferential agonists for the NPY-1 and NPY-2 receptor subtypes on voltage-dependent calcium currents in acutely dissociated postnatal rat nodose ganglion neurons. 2. Both low- and high-threshold calcium current components were present. NPY altered voltage-dependent calcium currents in approximately 50% of neurons studied. NPY (0.1-100 nM, ED50 6 nM) decreased the peak amplitude of transient high-threshold calcium currents in approximately 45% of the neurons. NPY (100 nM) decreased the peak amplitude of these currents 31 +/- 5% (mean +/- SE). However, in approximately 5% of the neurons NPY (100 nM) caused a reversible and reproducible increase in transient high-threshold calcium currents of 21 +/- 4%. NPY did not affect either transient low-threshold or slowly inactivating high-threshold calcium current components. 3. Application of the C-terminal fragment NPY 13-36 (100 nM), a preferential agonist for NPY-2 receptors, reversibly decreased the peak amplitude of transient high-threshold calcium currents by 26 +/- 5% in 9 of 20 cells (45%). Application of [Pro34]-NPY (100 nM), a preferential agonist for NPY-1 receptors, reversibly increased the peak amplitude of transient high-threshold calcium currents 20 +/- 4% in 23 out of 48 neurons (48%). Six of 20 neurons (30%) responded to application of both agonists. Neither the NPY-1 nor NPY-2 agonists affected transient low-threshold or slowly inactivating high-threshold calcium current components.(ABSTRACT TRUNCATED AT 250 WORDS)
Interaction Approach to Anomalous Spin Texture in Warped Topological Insulators

Field: Physics and Astronomy (Physical Sciences)

Interactions between the surface and the bulk in a strong topological insulator (TI) cause a finite lifetime of the topological surface states (TSS) as shown by the recent experiments. On the other hand, interactions also induce unitary processes, which, in the presence of anisotropy and the spin-orbit coupling (SOC), can induce non-trivial effects on the spin texture. Recently, such effects were observed experimentally in the $Bi_2X_3$ family, raising the question that the hexagonal warping (HW) may be linked with new spin-related anomalies. The most remarkable among which is the 6-fold periodic canting of the in-plane spin vector. Here, we show that, this anomaly is the result of a {\it triple cooperation between the interactions, the SOC and the HW}. To demonstrate it, we formulate the spin-off-diagonal self energy. A unitary phase with an even symmetry develops in the latter and modulates the spin-1/2 vortex when the Fermi surface is anisotropic. When the anisotropy is provided by the HW, a 6-fold in-plane spin-canting is observed. Our theory suggests that the spin-canting anomaly in $Bi_2X_3$ is a strong evidence of the interactions. High precision analysis of the spin-texture is a promising support for further understanding of the interactions in TIs.
Early Detection of Mycobacterium tuberculosis in BACTEC Cultures by Ligase Chain Reaction

Field: Medicine (Health Sciences)

ABSTRACT The LCx Mycobacterium tuberculosis ligase chain reaction system (Abbott Diagnostic Division, Abbott Park, Ill.) was used to detect M. tuberculosis in 150 consecutive BACTEC vials on the day on which a positive growth index (GI) was recorded. By LCx, M. tuberculosis DNA was detected in BACTEC vials on average 2.6 days before the presence of acid-fast bacilli could be confirmed by microscopic examination. A total of 106 of 108 M. tuberculosis isolates were detected without centrifugation from bottles presenting very low GIs (average, 70; median, 33). No false-positive result was obtained from nontuberculous mycobacteria or from isolates with contaminants.
Fact Sheet Occupational Exposure to Rabies Virus

Field: Health Professions (Health Sciences)

This fact sheet is for workers who may be exposed to the rabies virus on the job, and their employers. Three main groups are at risk: those who work with animal species that can transmit the virus, workers whose jobs may incidentally expose them to carrier animal species, and lab workers who use live rabies virus in research or vaccine facilities, or perform diagnostic tests. Human rabies is now very rare, due to the development of domestic animal control programs. In 1997, only four cases of human rabies were reported to the Centers for Disease Control (CDC). In the United States today, wildlife accounts for more than 90 % of the reported cases of animal rabies. In California, rabies is well established in the skunk and bat populations. Humans can be infected when an infected animal&apos;s saliva gets through an open wound (usually the animal&apos;s bite) or through a mucous surface such as the eyes, nose, or mouth. A new vaccine is being used that has fewer side effects than the previous vaccines. If you think you may have been exposed to a rabid animal, retrieve and quarantine or euthanize the animal for testing, see a physician as soon as possible, and contact animal control authorities.
Genetic diversity and response to selection for yield and component traits in selected F4 and F5 progenies of oat

Field: Agricultural and Biological Sciences (Life Sciences)

The present study was planned to record the response to selection and extent of genetic diversity in selected F4 and F5 generation progenies, which were derived from seven crosses of oats. The F4 and F5 progenies were evaluated in randomized block design over three replications during Rabi, 2019-20 and Rabi, 2020-21, respectively at the Experimental Farm of Fodder Section, CSKHPKV, Palampur. The utmost response to selection was depicted by grain yield per plant, fresh fodder yield per plant, biological yield per plant, harvest index, leaves per plant and plant height in most of the crosses. Hence, improvement through selection could be based on these traits. PCA studies revealed that the first five components accounted for more than 80% of the total variance among the progenies. Four PC in F4 and five PC in F5 generation possess eigen values > 1. The first principal component, i.e., PC1 accounted for the maximum proportion of total variability in the set of all variables, i.e., 36.97% and 30.29% in both F4 and F5 generations, respectively. The dendrogram showed that 34 genotypes of oat were grouped into three clusters in F4 generation and 33 genotypes from F5 into eight clusters. On the basis of divergence and cluster mean studies, it was suggested that maximum heterosis and good recombinants could be obtained in crosses between progenies of clusters II and III from F4 generation and clusters I, V, VII from F5 generation.
SMALL TISSUE DRYERS WITH HIGH CAPACITY FOR RAPID FREEZE-DRYING

Field: Medicine (Health Sciences)

In close connection to the development of a new histochemical technique the need for a small high capacity freeze dryer greatly increased. A convenient system was devised, which allows work with several independent drying chambers simultaneously. The cooling source is a standard refrigeration plant equipped with an expansion coil in a Dewar flask from which cold liquid is distributed to the separate drying units. The specimen carrier of each unit can take about twenty tissue pieces. Even though diffusion pump, cold finger trap, and other delicate components have been avoided, drying time is quite favourable; it may be as little as five hours for pieces of standard size. Moreover, the evacuation pump is well protected against vapor. The freeze dryer is built mainly of standard components or inexpensive modifications of these.
The impact of pollution control enforcements on FDI inflow to Thailand

Field: Economics, Econometrics and Finance (Social Sciences)

This article reexamines the pollution heaven hypothesis, using measureable environmental indicators to quantify the laxity of pollution control enforcements. The article examines the impact of pollution control enforcements on FDI inflow in industries across the spectrum as well as individual industries. The study was done on a global platform with separate groups of ASEAN countries and domestically within Thailand. Data from the World Bank, UNCTAD and Thailand’s Board of Investment between years 2008 to 2013 were used with panel data regression. Mixed results were obtained; low levels of pollution control enforcements significantly attract FDI inflow to ASEAN countries and East Asia Pacific Region, while in the cases of Europe, Central Asia and Latin America no significant result was found. For Thailand, as a host country, firm-level evaluation procedures using pollution intensity value together with laxity of pollution control enforcements were evaluated. Foreign investors from various countries consider that low levels of pollution control enforcements in Thailand reflected significantly and attracted their investment decisions.
Chromosome scattering occurs in karotypically normal cells.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

<p>(<b>A</b>) Selected images from time-lapse imaging sequences of cells expressing histone H2b:mRFP for HeLa FRT and hTERT-RPE1 cells treated with a CENP-E inhibitor. Time (in mins) is indicated on the lower right of each panel; time 0 is NEBD. The experimental scheme is depicted above the images. Scale bar, 5 µm. (<b>B</b>) Comparison and quantification of the cellular response to the CENP-E inhibitor. (<b>C</b>) Immunofluorescence images of scattered cells that are stained for DNA and centromere marker ACA. Individual chromatids are seen off the plate in the scattered state for both cells lines treated with the CENP-E inhibitor. Scale bar, 5 µm; magnified image 1 µm.</p>
Line-scan chromatic confocal microscopy for multi-depth imaging of skin tissue using deconvolution

Field: Medicine (Health Sciences)

In this paper, we present a line-scan chromatic confocal microscopy for rapid, multi-depth imaging of non-transparent skin tissue. Leveraging spectral dispersion encoding, this system enables the simultaneous acquisition of reflectance data across a depth range exceeding 180 μ m in skin tissue, effectively eliminating mechanical axial scanning and minimizing associated artifacts. With a lateral effective field of view (FOV) of 13.2 mm, the system provides a wide-field perspective for comprehensive tissue analysis. Furthermore, to overcome the typical limitations of lateral resolution in line-scan systems, we employ pre-calibrated deconvolution using an empirically determined point spread function obtained with a micro-spot mirror. We demonstrate deep-tissue tomography with ex vivo bovine skin tissue, achieving an increase in resolution from 45.25 lp/mm to 50.79 lp/mm post-deconvolution, as quantified using a USAF 1951 target. These results highlight the potential of line-scan chromatic confocal microscopy with pre-calibrated deconvolution as a powerful platform for multi-depth biomedical imaging applications requiring enhanced lateral resolution and contrast.
Metabolic Consequences of Sustained Suppression of Free Fatty Acids by Acipimox in Patients With NIDDM

Field: Medicine (Health Sciences)

To examine whether overnight suppression of free fatty acid levels reduces hepatic glucose production, 20 NIDDM patients were given a slow-release formulation of the antilipolytic agent acipimox, in a double-blind crossover manner at bedtime for 4 wk. During acipimox treatment, serum free fatty acid concentrations were suppressed between 2400 and 0600 by 64% (P &lt; 0.001), but no reduction in hepatic glucose production was observed (2.16 ± 0.16 vs. 2.23 ± 0.16 mg · kg−1 · min−1, acipimox vs. placebo). In contrast, from 0800 to 2000 a sustained 50% rise occurred in serum free fatty acids (P &lt; 0.001). As a consequence, the 24-h area under the free fatty acid curve was similar during both treatment periods. In the morning, the rise in free fatty acid concentration occurred despite identical serum acipimox concentrations as those measured at midnight, when free fatty acid levels were suppressed. Although energy expenditure was higher (P &lt; 0.05) during periods of elevated free fatty acid levels, the sums of energy expenditure measured in the morning and in the evening were similar during the acipimox and placebo periods. To exclude that the free fatty acid rise was caused by administration of acipimox only once at bedtime, additional experiments were performed administering acipimox every 2 h for 4 days. Despite similar acipimox concentration on day 1 and day 4 of this frequent dosing regimen, the free fatty acid concentrations were significantly higher on day 4 compared with day 1 (P &lt; 0.01). In conclusion, under these circumstances overnight lowering of serum free fatty acid by antilipolytic treatment does not reduce hepatic glucose production in patients with NIDDM. Instead, it results in a sustained daytime rise in free fatty acid, leading to unchanged 24-h free fatty acid levels. This compensatory free fatty acid rise may be necessary to maintain energy production unchanged. Long-term studies are required to answer the question whether it is possible to inhibit the appearance of a major energy substrate as free fatty acid during chronic therapy in patients with NIDDM.
Ex vitro acclimatization of Hippeastrum reticulatum (Amaryllidaceae) using different substrates

Field: Agricultural and Biological Sciences (Life Sciences)

ABSTRACT: Hippeastrum spp. are herbaceous species belonging to the family Amaryllidaceae, widely marketed worldwide as indoor plants. Aiming to characterize chemically and physically and to compare five substrates in acclimatization, micropropagated seedlings of Hippeastrum reticulatum var. striatifolium (Herb), with an average of four roots, two leaves and bulbs with a 4.7mm diameter, were transplanted to 50-cell polyethylene trays each containing the following substrates: T1 - vermiculite, T2 - carbonized rice husk (CRH), T3 - commercial (peat + vermiculite + CRH), T4 - coconut fiber, and T5 - composted Pinus bark. After transplantation, the trays were kept for 17 days at a greenhouse with intermittent irrigation by nebulization, and 80 days at a greenhouse on a bench with intermittent irrigation by capillarity. The experimental design was randomized blocks with seven replications and ten seedlings per plot. The acclimatization of seedlings was efficient for the substrates tested despite the differences verified by chemical and physical characterization. The mean survival rate was 96%. However, seedlings acclimatized in the T5 substrate showed a qualitative improvement due to a higher formation of roots, leaves and fresh matter.
Cowpea Curculio Feeding Stimulants from Southernpea Pods1

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract Compounds active as feeding stimulants for cowpea curculio ( Chalcodermus aeneus Boheman) were quantitatively determined by laboratory bioassays in pods of 5 cultivars of southernpeas ( Vigna unguiculata (L.) Walpers). Feeding response was tested on intact sections of fresh pods and on filter paper wrapped plugs of agar and water-extracts of hulls with seeds removed. Water extracts were partitioned with ether and the tests of the activity of both fractions indicated that the active compounds were lipid in nature. Active compounds extracted from a susceptible cultivar were added to the extract of a resistant cultivar and feeding response was increased nearly 10 fold. Quantitative and qualitative differences in fatty acid composition between resistant and susceptible cultivars were shown by gas chromatography. The amounts of eicosenoic acid were directly related to curculio feeding response to the cultivars.
Epidemiology, Survival, and Clinical Characteristics of Inclusion Body Myositis

Field: Medicine (Health Sciences)

Objective We performed a population‐based study on inclusion body myositis with the primary aims to define the prevalence, survival rate, and incidence, and to investigate the symptom profiles associated with disease duration and sex over a 33‐year period. Methods Patients diagnosed between 1985 and 2017 in Region Västra Götaland, Sweden, were identified according to the European Neuromuscular Centre diagnostic criteria from 2011. Results We identified 128 patients, 89 men and 39 women, with the strict clinicopathological definition of inclusion body myositis. The prevalence was 32 per million inhabitants, 19 per million women and 45 per million men, by December 31, 2017. Mean incidence was 2.5 per million inhabitants and year. Mean age at symptom onset was 64.4 years with quadriceps weakness being the most common presenting symptom followed by finger flexor weakness. Dysphagia was a common presenting symptom being more frequent in women (23%) than men (10%) and was during the disease course reported in 74% of men and 84% of women. Seventy‐three patients were deceased, with a mean survival of 14 years from symptom onset. Survival rates from both diagnosis date and symptom onset were decreased compared to the matched population. Twenty‐one percent of the patients had an additional autoimmune disease. A cross‐sectional analysis of autoantibodies in 50 patients and 28 matched controls showed autoantibodies to cytosolic 5′‐nucleotidase 1A in 40% of the patients and 3.6% of controls. Interpretation Inclusion body myositis is an autoimmune disease with decreased survival rate and with marked sex differences in both prevalence and clinical manifestations. ANN NEUROL 2022;92:201–212