jimnoneill/paper-to-field-training huggingface dataset:
Combinatorial Libraries and Molecular Recognition - Match or Mismatch?

Field: Chemistry (Physical Sciences)

During the past decade combinatorial libraries have emerged as a major tool for drug discovery and drug development. Especially “one-bead-one-structure” libraries can be a powerful means for the discovery of ligands to natural and synthetic hosts and vice versa. Encoded combinatorial libraries have been used to disclose ligands for well-designed macrocyclic host molecules and to elucidate their specificities for peptide sequences. These studies led via receptors with more flexibility to simple host molecules without elaborate design that are accessible to combinatorial synthesis. These findings opened a realm of possibilities and applications. An intriguing one is the development of chemical sensors for analytes that are otherwise hard or only unspecifically detected. Furthermore, such libraries and the techniques that were developed to handle them have been used to find new catalysts and enzyme mimics.
Staggered Sampling for Energy Efficient Data Collection

Field: Computer Science (Physical Sciences)

Efficient and complete data collection is one of the most important tasks in wireless ad-hoc sensor networks. Additionally, the collection of the full data set should be performed in the most resource efficient way, thus prolonging the battery lifetime of the network. We introduce a new approach for energy efficient data collection through the use of staggered sampling. Staggered sampling means that at each sampling moment (epoch) only a small percentage of sensors collect (sample) data. The proposed approach leverages on statistical relationships between samples taken from different sensors and/or at different epochs for the prediction of the non-sampled sensor data. The main goal of the approach is to ensure complete collection of data during a periodic cycle while minimizing the number of sensor readings collected at any point in time. Complete data collection is confirmed by ensuring that each sensor is either sampled at each epoch or the data sample can be accurately recovered though model prediction of the sampled sensors. The proposed approach consists of two main phases. First, efficient modeling of the prediction relationship between two sensors using kernel smoothing over different time lags is performed. Second, the selection of epochs at which each sensor is to sample the data is determined. A 0-1 integer linear programming formulation is used to address this NP-complete assignment problem optimally on relatively large instances. We demonstrate the effectiveness of the approach on traces from actually deployed networks for sensor of two modalities: temperature and humidity.
ACCRUAL ACCOUNTING, FOUNDATION FOR THE FINANCIAL REPORTING INTO THE PUBLIC SECTOR ENTITIES.

Field: Economics, Econometrics and Finance (Social Sciences)

The development of the accounting system of the public sector entities at mondial level has focused on taking up the accrual accounting as foundation for the financial reporting and totally or partially giving up the cash accounting. Within this context, by this research, we define the coordinates of the accrual accounting, we analyse the adoption of it as a financial reporting basis into the public sector at international level and also the implications of completing the cash accounting with the accrual accounting into the Romanian public sector. The research takes into consideration a synthesis of the ideas published upon this topic into the professional literature, the regulations issued by the national and international accounting regulators, by accounting bodies.
SOIL AS A FACTOR INFLUENCING THE MANGROVE FOREST COMMUNITIES IN TALIDENDANG BESAR, RIAU

Field: Agricultural and Biological Sciences (Life Sciences)

OneÂ transect of 10 m x 900 m wasÂ constructed perpendicularÂ toÂ the sea edgeÂ to knowÂ the patternÂ of mangrove forest communities from the sea edge through the inland area. Then, one sample plot of 50 m x 50 m was established at each forest community to explore its vegetation structure and soil characteristics. The results show that in Talidendang Besar area, there are three mangrove forest communities stretching from the sea edge to the inland, namely Bruguiera parviflora, B. sexangula and B. sexangula-Nypa fruticans. The soil factors such as pH.EC (electrical conductivity), % K, % Na, C-organic, N-total, NH4 (ammonia), and CECÂ (cation exchangeÂ capacity) wereÂ regardedÂ importantÂ inÂ influencingÂ theÂ pattern ofÂ the mangroveÂ forest communities.
An empirical multidimensional analysis on sustainable tourism: the dynamics of carrying capacity

Field: Environmental Science (Physical Sciences)

Carrying capacity is a framework often used to attain the goal of sustainable tourism. However, current methods to determining carrying capacity are unable to holistically integrate different components that need to be considered in the achievement of sustainable tourism. Due to the dynamic behaviour of tourist attractions, there is a necessity for carrying capacity to be viewed from a systems perspective through identifying and integrating the dynamic relationships between social, ecological, and economic factors that influence the carrying capacity of a tourism system. A simulation model was developed to analyse the dynamic factors that give rise to the sustainability of the Hinagdanan Cave, an ecotourism attraction in the province of Bohol, the Philippines. Simulation results showed that the limiting factor of the cave system is the crowd level perception factor and that the cave has a carrying capacity of 27 persons. The determination of carrying capacity through the analysis of different components in a tourism system is possible given that the model can be used as an archetype; and at the same time, it can also be tailored-fit to address the uniqueness of characteristics and attributes of any tourism system.
The category of chronotope in Akathist genre

Field: Arts and Humanities (Social Sciences)

The object of this research is the category of chronotope &ndash; a significant complex text category that reflects the semantic coordinates of the text and extra-textual reality. The category of chronotope intertwines the isomorphic components of textual time and textual space. The Akathist genre belongs to an insufficiently studied functional religious style. Examination of the category of chronotope in the context of Akathist genre is relevant trend in the modern functional stylistics. The research material contains the texts of Orthodox Akathists dedicated to the canonized saints. The objectivity of scientific research is justified by the choice of texts from various time periods. The author applies the method of categorical-textual analysis, which reveals the linguo-stylistic technique of formation of the components of general communicative-pragmatic meaning of the text. The novelty is defined by the fact that the use of categorical-textual method in the analysis of the Akathist type of text, interpreted as a generalized textual structure with typical genre-forming components, allows determining with a high degree of objectivity the genre specificity of Akathist and religious functional style. As a result of the conducted research, the author highlights the categorical-textual typology of chronotope, which characterizes the systematic uniformity of Akathist texts. The article describes the methods of explication of the sacred, objective (objectively-sacred and objectively-profane), and subjective (subjectively-sacred and subjectively-profane) types of time and space. Temporal indicators and locative units of the determined types of chronotope reconstruct the dichotomy of the divine and the earthly in the Akathist, which is inherent to the Christian worldview and constructively substantiates the uniqueness of the religious functional style. The conducted analysis reveals the communicative-pragmatic focus of the complex textual category of chronotope. The research materials can be used as an illustrative textbook in the practical course of the stylistics of modern Russian language.
Distribution of glycoconjugates in mouse fibroblasts with varying degrees of tumorigenicity

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Analysis of glucosamine labeled glycoconjugates in cultured cells has been made comparing 2 clones and the parent embryonic mouse cell line. Hyaluronic acid, heparan sulphate, and chondroitin sulphate as well as a complex mixture of glycopeptides were found in the medium, the trypsinate, and the trypsinized cells, although the distribution was not uniform. The 3 cell lines had very similar in vitro growth properties, including their plating efficiency in viscous medium. However, the tumorigenicity of the cells, determined in syngeneic mice, was found to differ. All 3 cell lines were found to have similar glycoconjugate distributions, although a slight relative increase in labeled hyaluronic acid was found in the more tumorigenic mass cell line than either of the clones. The possible significance of this increase is discussed.
Reliquantha variipes gen. & sp. nov., a peculiar new taxon of Anthomyzidae (Diptera) from Great Britain with uncertain relationships

Field: Agricultural and Biological Sciences (Life Sciences)

Roháček, Jindřich (2013): Reliquantha variipes gen. & sp. nov., a peculiar new taxon of Anthomyzidae (Diptera) from Great Britain with uncertain relationships. Acta Entomologica Musei Nationalis Pragae 53 (2): 793-814, DOI: 10.5281/zenodo.5740784
How to Be an Agnostic: an Aphoristic A–Z

Field: Arts and Humanities (Social Sciences)

HEGEL ONCE REMARKED: 'The owl of Minerva spreads its wings only with the falling of the dusk.' Mary Midgley deploys the image in her memoir: 'The thought for which I want to use it is that wisdom, and therefore philosophy, comes into its own when things become dark and difficult rather than when they are clear and straightforward. That — it seems to me — is why it is so important.'KeywordsChristian TraditionRadical UncertaintyBeautiful ThingObsessional NeurosisSocratic QuestionThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Underground transmission lines for high power AC and DC transmission

Field: Energy (Physical Sciences)

The latest state of the art and ongoing research about high power gas-insulated underground transmission lines as well as the latest technical improvements are presented in this contribution. The basic technology is presented and the advances of the technology with respect to different installation options are discussed. A very high power transmission capability, a low capacitance, lower resistive losses compared to power cables and overhead lines, negligible magnetic fields, no ageing phenomena of the insulating system and a maintenance free design are the main benefits. In consequence, GIL technology for high power HVDC transmission is actually under development.
A Rare Case of Occupational Aniline Poisoning: Management in a Limited-Facility Setting

Field: Medicine (Health Sciences)

Introduction Cyanosis along with altered mental should bring all the possible ethiologies into her mind in a minimum of time, based on the trauma, medical, environmental, and occupational history of the patient. Poisoning with methemoglobinemia inducing agents is one of the most important differentials especially when a history of occupational exposure to these agents is present. Case Report The patient, a 41-year-old healthy woman and engineer, experienced symptoms after exposure to aniline leading to dizziness and weakness, prompting a visit to the emergency department with cyanosis and low oxygen saturation. Initial vital signs showed decreased oxygen levels and elevated respiratory rate with normal ABG values despite ongoing cyanosis. Patient required intubation, mechanical ventilation, and was diagnosed with ARDS based on chest X-ray findings. Management included IV diuretics, 100% oxygen, and antioxidant treatment in the ICU. Despite treatment, oxygen saturation remained at 88% on the first day. Conclusion This case is a reminder of the importance of taking occupational history and management of aniline toxicity in a setting where methylene blue, the drug of choice for aniline toxicity, is not available in the drug stock.
Erythema Multiforme Induced by Secukinumab

Field: Medicine (Health Sciences)

Conforti, Claudio MD; Currado, Damiano MD; Vezzoni, Roberta MD; Corneli, Paola MD; Bussani, Rosanna MD; Navarini, Luca MD; Magaton-Rizzi, Giovanni MD; Fischetti, Fabio MD; Di Meo, Nicola MD; Zalaudek, Iris MD Author Information
The Literary Culture of the Renaissance Venetian Empire

Field: Arts and Humanities (Social Sciences)

This article examines a corpus of fifteenth-century geographical and epigraphical literature representing the Venetian Mediterranean empire. It was collected and read by Venetian patrician men who were both humanists and part of the political class that governed Venice and its empire. Navigating between literary analysis and history of the book, the article first examines the Venetian legacy of the writings of Cyriac d’Ancona, before investigating the provenance of individual books and their collecting histories. Then, it turns to study the marginalia and annotations in these books by Venetian readers. It suggests that, in its composite construction, this literature provided ways for Venetian readers to imagine their own composite maritime state, particularly its history. Building on recent art historical analysis, I argue that the legitimacy that the aura of antiquity gave to the Venetian imperial enterprise was one of persistence: the Mediterranean empire was a space in which Venetians could encounter a living Greco-Roman imperial past.
Evolution Of Retail Sector In India

Field: Business, Management and Accounting (Social Sciences)

The retail sector scenario in India is very dynamic and varied. With the phenomenal growth in this sector, India has become an attractive destination for the foreign players. Which witnessed radical changes in the formats and retail marketing structure in the past few decades? This rapid growth has shown the way to invasion of organized retailing in both urban and rural areas. Traditionally the very nature of Indian retail sector is fragmented and unorganized. All these factors have led to a continuous change in consumer purchase behavior and marketing philosophies. The present paper is devoted to explain the concepts of retailing and explore the various stages through which the retail industry has evolved.
Medical education during the COVID-19 pandemic: problems and solutions

Field: Health Professions (Health Sciences)

Modern education, including medical, is currently experiencing unprecedented difficulties caused by the growing incidence of new coronavirus infection. The difficulties are primarily due to the fact that most educational institutions in Ukraine and around the world have switched to remote operation. Thus, educational organizations, and especially teachers, face an unfamiliar situation, and many do not know how to support students in these new conditions or to adhere to the curriculum and train students for coming exams. The situation is complicated by the fact that the peak incidence coincided with the end of the school year, the most difficult period for both universities and students and clinical residents. Many of them have graduated and have taken qualification exams, procedures of primary and primary-specialized accreditation. How in the current situation to continue teaching students effectively? How to help them develop new skills? How to apply the assessment and in what form? Is it possible to conduct examinations in the format of an objective structured clinical examination (OSCE)? How will medical education change after the restrictions are strengthened? These and other topical issues are covered by the authors in this review, based on the experience of foreign colleagues and their research.
Limitation of the therapeutic effort: ethical and legal justification for withholding and/or withdrawing life sustaining treatments

Field: Health Professions (Health Sciences)

Withholding and withdrawing a treatment already established are two forms of limitation of the therapeutic effort (LTE). The question of undergoing or not undergoing lifesaving medical treatments is not restricted to a specific health care context, as it refers to a variety of treatments, and it does not concern a restricted group of diseases. LTE has become part of the options compatible with the good clinical practice, in accordance with a deep change in modern medicine’s ‘mission’ along with the increased importance attributed to the patient’s general, personal condition, and to the quality of his/her life. However, LTE remains a controversial issue, and it still has many opponents, in particular, but not exclusively, in those cases in which the question is the withdrawal of treatments, which a widespread conventional wisdom considers ethically and legally different from not initiating treatments. But is it justified to address LTE as a totally controversial issue, especially in case of withdrawal of treatments? The paper answers negatively by arguing that there are criteria both in medical ethics and in law often adequate enough to remove doubts, and to guide decisions and actions.
Knowing-how: Problems and Considerations

Field: Arts and Humanities (Social Sciences)

In recent years, a debate concerning the nature of knowing-how has emerged between intellectualists who claim that knowledge-how is reducible to knowledge-that and anti-intellectualists who claim that knowledge-how comprises a unique and irreducible knowledge category. The arguments between these two camps have clustered largely around two issues: (1) intellectualists object to Gilbert Ryle's assertion that knowing-how is a kind of ability, and (2) anti-intellectualists take issue with Jason Stanley and Timothy Williamson's positive, intellectualist account of knowing-how. Like most anti-intellectualists, in this paper I will raise objections to Stanley and Williamson's account of knowing-how and also defend the claim that ability is necessary for knowing-how attributions. Unlike most discussions of knowing-how, however, I will return to more Rylean considerations in order to illustrate that any intellectualist account of knowing-how, not simply Stanley and Williamson's preferred variety, will fail because it will be unable to account for fundamental differences in the knowledge required to instantiate an ability and the knowledge involved in propositional thought.
Prevention of Regurgitation

Field: Medicine (Health Sciences)

course we meant women without abnormal personalities.We agree that the more abnormal the person- ality of the woman the less well-adjusted is she also likely to be after the termination, which is hardly surprising; but Hook's' findings (based on 249 subjects refused termination) appear to show that such women may be even less well if they have to keep the unwanted child.Hook writes: " A considerable number of years after the application, there was still a definite need for psychiatric care and further treatment of the con- flicts connected with the unwanted pregnancy."This author clearly showed that "not wanting" may not be just a " temporary state of mind" but is often an accurate forecast of a long drawn- out struggle, a conclusion similar to that reached
PENERAPAN METODE AHP PADA PENENTUAN PRIORITAS PROYEK AIR BERSIH DI KABUPATEN ASAHAN

Field: Decision Sciences (Social Sciences)

Abstract: Asahan Regency is one of the 33 regencies/cities in North Sumatra Province. Coastal areas are still lagging behind because they are far from urban areas so that the government pays little attention to it, especially regarding clean water. Clean water in the area can be said to be unfit for use. So that people find it difficult to get clean water for drinking, washing and bathing. These problems can be solved by programs to improve clean water infrastructure and facilities, such as drilling wells and allocating river water, so that they can provide optimal services for clean water, which has a very strong relationship with the economic growth of a region and the socio-cultural life of the community. Determining the priority scale for clean water must look at various criteria so as to produce accurate and precise results. Space so as to allow the results to be less accurate and not on target as well as errors in determining which clean water should be prioritized, so that a decision support system is needed that can assist in determining which villages have the right to take precedence in the priority of clean water projects. The method used for the decision support system is AHP method. Keywords: Priority Determination of Clean Water Projects; AHP Method. Abstrak: Kabupaten Asahan merupakan salah satu kabupaten dari 33 kabupaten/kota yang ada di Provinsi Sumatera Utara. Di wilayah Pesisir masih tertinggal karena letaknya yang jauh dari perkotaan sehingga kurang diperhatikan oleh pemerintah, terutama mengenai air bersih. Air bersih di wilayah tersebut bisa di bilang tidak layak untuk digunakan. Sehingga masyarakat kesulitan untuk mendapatkan air bersih baik itu untuk diminum, menyuci dan mandi. Dengan mempertimbangkan hal tersebut maka perlu diterapkan penentuan skala prioritas yang dapat digunakan sebagai suatu acuan dalam penyusunan program proyek untuk tahun anggaran berikutnya. Penentuan skala prioritas air bersih tersebut harus melihat dari berbagai kriteria sehingga menghasilkan hasil yang akurat dan tepat, selama ini penetuan masih berdasarkan musrembang dari pihak Dinas Pekerjaan Umum dan Penataan Ruang sehingga memungkinkan hasil kurang akurat dan kurang tepat sasaran serta terjadinya kesalahan dalam penentuan air bersih yang harus diutamakan, sehingga diperlukan suatu sistem pendukung keputusan yang dapat membantu dalam menentukan desa mana yang berhak didahulukan dalam prioritas proyek air bersih Metode yang digunakan untuk sistem pendukung keputusan adalah Metode AHP. Kata Kunci : Penentuan Prioritas Proyek Air Bersih; Metode AHP.
Dolichonychia in Women with Marfan Syndrome

Field: Medicine (Health Sciences)

Dolichonychia refers to nails that are elongated and slender. This nail morphology has been described in single case reports of patients with Ehlers-Danlos syndrome, hypohidrotic ectodermal dysplasia, and Marfan syndrome.The length and width of fingernails were measured in patients with Marfan syndrome and in individuals without the syndrome. A fingernail index was calculated for each person. A non-parametric sign test was used to compare the mean fingernail index of patients with Marfan syndrome and control subjects.The fingernail index ranged from 0.92 to 1.52 in patients with Marfan syndrome and from 0.77 to 1.30 in control individuals. The median fingernail index in women with Marfan syndrome (1.455) was significantly greater than the median fingernail index in women control subjects (1.080) (P = 0.035). Dolichonychia, defined as a fingernail index greater than or equal to 1.30, was present in six of eight (75%) of women with Marfan syndrome as compared with only one of 40 (2.5%) of women control subjects.Dolichonychia is a physical finding present in some patients with Marfan syndrome. The detection of long narrow fingernails in women should suggest the possibility of Marfan syndrome.