jimnoneill/paper-to-field-training huggingface dataset:
Gap junction-mediated fluorescent dye spread in WB-F344 cells is blocked by the GJIC inhibitor meclofenamate sodium.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The scrape loading dye transfer (SL-DT) assay was performed in WB-F344 cells that were either (lower row) or not (upper row) pre-treated for 1h with 50 μM of the GJIC inhibitor meclofenamate sodium. In the inhibitor-treated sample, the Lucifer Yellow CH (LY) solution used for the SL-DT assay was also supplemented with 50 μM meclofenamate sodium. Scale bar: 100 μm. (TIFF)
Complexity and Human Society

Field: Social Sciences (Social Sciences)

Human society involves many networks of human relationships, aswell as the interplay between people, institutions and processes.Social organization has evolved many ways of reducing and contain-ing complexity, especially encapsulation, but several processes stilllead to unplanned social trends. These processes include cascadingcontexts, positive feedback, changes in network connectivity, andbrittleness of "divide and rule" strategies. Examples of these areevident in the social side effects of new technologies.
Enzyme Studies In Serous Otitis Media

Field: Medicine (Health Sciences)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Otolaryngology–Head & Neck Surgery HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Otolaryngology–Head & Neck Surgery journal
Eta Carinae: An Evolving View of the Central Binary, Its Interacting Winds and Its Foreground Ejecta

Field: Physics and Astronomy (Physical Sciences)

Abstract FUV spectra of η Car, recorded across two decades with HST/STIS, document multiple changes in resonant lines caused by dissipating extinction in our line of sight. The FUV flux has increased nearly tenfold, which has led to increased ionization of the multiple shells within the Homunculus and photodestruction of H 2 . Comparison of observed resonant line profiles with CMFGEN model profiles allows separation of wind–wind collision and shell absorptions from the primary wind P Cygni profiles. The dissipating occulter preferentially obscured the central binary and interacting winds relative to the very extended primary wind. We are now able to monitor changes in the colliding winds with orbital phase. High-velocity transient absorptions occurred across the most recent periastron passage, indicating acceleration of the primary wind by the secondary wind, which leads to a downstream, high-velocity bow shock that is newly generated every orbital period. There is no evidence of changes in the properties of the binary winds.
Evaluasi Strategi Bisnis Balanced Scorecard Pada PT. Raja Indonesia Perkasa

Field: Business, Management and Accounting (Social Sciences)

PT Raja Indonesia Perkasa is engaged in the manufacturing industry in the textile sector by producing equipment and wholesale trade in household appliances and furniture trying to evaluate the company's performance. The purpose of this study was to determine the evaluation of the strategy according to the vision and mission applied to PT Raja Indonesia Perkasa using the balanced scorecard concept. Strategy evaluation in the company is useful for assessing the performance of a company, knowing the company's position in an effort to achieve its goals. The increasingly fierce competition in the 21st century and the economic turmoil during the global pandemic due to Covid-19 require PT Raja Indonesia Perkasa as a company that also carries out exports and imports to stay afloat. Descriptive quantitative research methodology with two sources of primary and secondary data. Data processing method using Balanced Scorecard analysis. The researcher chose this method because, from a subjective point of view, the researcher saw the success of the business run by the company PT Raja Indonesia Perkasa which is getting more and more enthusiasts or consumers in the midst of fierce competition in the business world that is happening today. The results of this study indicate that the indicators for measuring the performance of the financial perspective are the best with a score of 145,06%, followed by the customer perspective on average 55% said to be good, the business perspective on average 31.19% said to be good, growth and learning an average of 2.4% is said to be less good.
Prevalence and intensity of urogenital and intestinal schistosomiasis among primary school children in rural districts of Senegal

Field: Medicine (Health Sciences)

Schistosomiasis is a public health problem in Senegal with unevenly distributed prevalence. The purpose of this study was to assess the prevalence and intensity of Schistosoma haematobium and Schistosoma mansoni infections among primary school children in eight districts of Senegal. A cross-sectional survey including school children aged from 7 to 13 years were included and was conducted in 3 ecological areas. Urine and stool samples were collected from for detection of S. mansoni and S. haematobium using Kato-Katz method and urine filtration, respectively. One thousand one hundred and thirty-three (1133) children were enrolled with 51.73% of girls. Among them, 1123 provided urine and stool samples. The overall prevalence of S. haematobium infection was 25 and 74% of the children presented low infection intensity (1-49 eggs/10 ml). Ecological area 2 (Kaffrine region) was more affected with 32%, whereas paradoxically ecological area 3 (Kolda and Ziguinchor) where transmission is permanent, had the lowest prevalence (13%). Regarding S. mansoni infection, the overall prevalence was 0.9% with 80% of low infection intensities (1-99 eggs/g stool) and all cases were observed in the ecological area 3. This study showed that schistosomiasis is still endemic in Senegal and revealed an evident need for systematic administration of school-based chemotherapy program using Praziquantel. Also, community engagement is needed to reduce transmission of the disease.

Key words: Urogenital schistosomiasis, intestinal schistosomiasis, primary school children, Senegal.
Synchronous design of avionic applications based on model refinement

Field: Computer Science (Physical Sciences)

In this article, we address the design of avionic applications based on an approach, which relies on model refinement. This study is done within the synchronous framework, which has solid mathematical foundations enabling formal methods for specification, verification and analysis, transformations, etc. In the proposed approach, we first consider a functional description of a given application using the SIGNAL language. This description is independent of a specific implementation platform. Then, some transformations that fully preserve the semantics of manipulated SIGNAL programs are applied to the description such that a representation reflecting an integrated modular avionics architecture results.
Immunoinformatics Approach to Design Multi-Epitope-Based Vaccine against Machupo Virus Taking Viral Nucleocapsid as a Potential Candidate

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The family members of Arenaviridae include members of the genus Machupo virus, which have bi-segmented negative sense RNA inside the envelope and can be transferred to humans through rodent carriers. Machupo virus, a member of the mammarenavirus genus, causes Bolivian hemorrhage fever, its viral nucleocapsid protein being a significant virulence factor. Currently, no treatment is available for Bolivian hemorrhage fever and work to develop a protective as well as post-diagnosis treatment is underway. Adding to these efforts, this study employed a reverse-vaccinology approach to design a vaccine with B and T-cell epitopes of the viral nucleocapsid protein of the Machupo virus. Five B-cell specific, eight MHC-I restricted, and 14 MHC-II restricted epitopes were finalized for the construct based on an antigenicity score of >0.5 and non-allergenicity as a key characteristic. The poly-histidine tag was used to construct an immunogenic and stable vaccine construct and 50S ribosomal 46 protein L7/L12 adjuvant with linkers (EAAAK, GPGPG, and AYY). It covers 99.99% of the world’s population, making it highly efficient. The physicochemical properties like the aliphatic index (118.31) and the GRAVY index (0.302) showed that the vaccine is easily soluble. The overall Ramachandran score of the construct was 90.7%, and the instability index was 35.13, endorsing a stable structure. The immune simulations demonstrated a long-lasting antibody response even after the excretion of the antigen from the body in the first 5 days of injection. The IgM + IgG titers were predicted to rise to 6000 10 days post-injection and were illustrated to be stable (around 3000) after a month, elucidating that the vaccine would be effective and provide enduring protection. Lastly, the molecular interaction between the construct and the IKBKE receptor was significant and a higher eigenfactor value in MD simulations confirmed the stable molecular interaction between the receptor and the vaccine, validating our construct.
287 Impact of Post-hospital Syndrome on Penile Prosthesis Outcomes: A Period of Global Health Risk

Field: Medicine (Health Sciences)

Patients experience a post-discharge transient period of heightened, generalized health risk; a phenomenon known as post-hospital syndrome (PHS). 1 Throughout a hospitalization, harmful alterations in nutrition, sleep cycles, cognition, pain/discomfort, and conditioning create a period of global health vulnerability that is independent of the acute illness that precipitated the index hospitalization. To date, it is unknown whether prior hospitalization affects surgical outcomes for penile prosthesis placement. This study aims to assess the impact of a preoperative hospitalization on outcomes following penile prosthesis surgery and to optimize surgical timing following an inpatient admission. The Healthcare Cost and Utilization Project State Inpatient and Ambulatory Databases for California (2007-2011) and Florida (2009-2014) were utilized. Patients were identified as having undergone prosthesis placement by ICD-9 and CPT codes. The primary exposure was post-hospital syndrome, defined as any inpatient admission ≤90 days prior to prosthesis placement. Patients were further categorized by how recently their inpatient hospitalization occurred. The primary outcome was 30 day readmissions. Secondary outcomes included length-of-stay, device complications and postoperative complications.
Sources and Constituents of Two Western Malaysian Dart Poisons

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Journal Article Sources and Constituents of Two Western Malaysian Dart Poisons Get access N G Bisset, N G Bisset Department of Pharmacy, Chelsea College, University of London Manresa Road, London, SW3 6LX Search for other works by this author on: Oxford Academic Google Scholar K H C Baser, K H C Baser Department of Pharmacy, Chelsea College, University of London Manresa Road, London, SW3 6LX Search for other works by this author on: Oxford Academic Google Scholar J D Phillipson J D Phillipson Department of Pharmacognosy, The School of Pharmacy, University of London 29/39 Brunswick Square, London, WC1N 4AX Search for other works by this author on: Oxford Academic Google Scholar Journal of Pharmacy and Pharmacology, Volume 29, Issue Supplement_1, December 1977, Page 17P, https://doi.org/10.1111/j.2042-7158.1977.tb11485.x Published: 12 April 2011
A novel electron-beam-based photomask repair tool

Field: Engineering (Physical Sciences)

High-resolution electron-beam assisted deposition and etching is an enabling technology for current and future generation photo mask repair. NaWoTec in collaboration with LEO Electron Microscopy has developed a mask repair beta tool capable of processing a wide variety of mask types, such as quartz binary masks, phase shift masks, EUV masks, and e-beam projection stencil masks. Specifications currently meet the 65 nm device node requirements, and tool performance is extendible to 45 nm and below. The tool combines LEO's ultra-high resolution Supra SEM platform with NaWoTec's e-beam deposition and etching technology, gas supply and pattern generation hardware, and repair software. It is expected to ship to the first customer in October this year. In this paper, we present the tool platform, its work flow oriented repair software, and associated deposition and etch processes. Unique features are automatic drift compensation, critical edge detection, and arbitrary pattern copy with automatic placement. Repair of clear and opaque programmed defects on Cr, TaN, and MoSi quartz masks, as well as on SiC and Si stencil masks is demonstrated. We show our development roadmap towards a production tool, which will be available by the end of this year.
Abstract 352 Current trends in the use of common pain medications for acute painful conditions of preschool children in the pediatric emergency department in the United States

Field: Medicine (Health Sciences)

Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts Submit your manuscript Enter your Email address: Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy. Subscribe to eTOC Secondary Logo Journal Logo All Articles Images Videos Podcasts Blogs Advanced Search Toggle navigation Subscribe Register Login Articles & Issues Current IssuePrevious IssuesPublished Ahead-of-Print For Authors Submit a ManuscriptInformation for AuthorsLanguage Editing ServicesAuthor Permissions Journal Info About the JournalEditorial BoardAdvertisingOpen AccessSubscription ServicesReprintsRights and Permissions All Articles Images Videos Podcasts Blogs Advanced Search
REDEFINITION OF THE TOPOGRAPHIC LOCALISATION OF THE THENAR MOTOR BRANCH OF THE MEDIAN NERVE

Field: Medicine (Health Sciences)

Purpose: The aim of this study was to redefine the localization of the thenar motor branch (TMB) of the median nerve in relation to the surface landmarks which are in routine use. Methods: The study was performed in 37 hands of 34 patients who underwent carpal tunnel release. All of the patients were women and the mean age was 50 (35–67). A radiological marking technique was used to determine the localization of the TMB, the middle finger radial side line and the Kaplan’s cardinal line. For marking TMB a circumscribing soft radioopaque yarn was used while the surface landmark lines were demonstrated by taping one K-wire for each. An image intensifier print image was obtained for each case and the distances between the markers of the TMB and the wires were measured. Results: The TMB had a mean ulnar offset of 12.6 mm (4.0–19.7) from the middle finger radial side line and located 4.4 (0–9.5) mm proximal to the cardinal line. Conclusion: During the carpal tunnel release operations one must pay more attention to the localization of the TMB of the median nerve because it was found to be 12.6 mm ulnar than that was described in classic literature.
"Metathetic Parallelism" -- An Unrecognized Subtype of Synonymous Parallelism

Field: Arts and Humanities (Social Sciences)

IT 1s WELL KNOWN that in biblical poetry it is not necessary for each word element of a synonymous to occupy the identical syntactic position in each corresponding stich. When it does not-and this is of frequent occurrence-it is known as chiastic parallelism. Using for the sake of simplicity a 2:2 meter, synonymous may appear either as ab//a'b' or, chiastically, as ab//b'a'. What has gone unrecognized, however, is that an object or a predicate that logically or grammatically or formulaically belongs to one stich may be interchanged at times with that of the corresponding stich resulting, chia~tically, in a strangely striking synonymous parallelism. Using again a 2:2 meter, chiastic may be either of the type of ab//b'a' or, metathetically, of the ab'//a'b type (or, in its varied form, ab'//ba'). To differentiate between these two types, I propose to name the second type metathetic parallelism because the corresponding objects or predicates are transposed; or proleptic parallelism because, in this arrangement, the content of the second stich is already anticipated in the first stich. However, before entering into an extended analysis of the nature of this parallelistic type, its etiology and teleology, we must first proceed to demonstrate its existence. This will be done by a close examination of the verses which follow .1
Adaptive Learning Models for Gifted and Talented Students: Global Perspectives and Implementation Challenges

Field: Social Sciences (Social Sciences)

This study examines adaptive learning models designed to optimize the potential of gifted and talented students from a global perspective. Using a systematic literature review (SLR) methodology, 21 articles from high-ranking journals (Q1 and Q2) and relevant academic books published between 2021 and 2024 were analyzed. The analysis identifies three primary models: the Enrichment Triad Model (ETM), the Differentiated Instruction Model (DIM), and the Autonomous Learner Model (ALM). Each model emphasizes critical elements such as deep learning experiences, curriculum flexibility, mentoring, and technology integration to foster creativity, critical thinking, and independent learning. The findings highlight the importance of adaptive educational paradigms that address not only the academic needs but also the social and emotional development of gifted students. The study also identifies significant challenges in implementing these models, particularly in developing countries like Indonesia, where resources and institutional support are often limited. The results provide practical insights into tailoring educational policies to meet the unique needs of gifted students, emphasizing the need for a balanced integration of global frameworks with local contexts. Future research is encouraged to explore adaptive learning implementations in diverse sociocultural settings to ensure equitable and inclusive education for gifted learners worldwide.
Analysis of Barkhausen Noise Signals of Samples Fe–1wt % Cu

Field: Materials Science (Physical Sciences)

The present work is based on the analysis of Barkhausen Noise (BN) signals, obtained from a group of samples formed by Fe–1 wt % Cu. They were made in Japan with the purpose to simulate possible processes that change the microstructure of pressures vessels of in service nuclear reactors. These vessels are made of a low ferritic steel alloy, with presence of Cu impurities. Twelve samples were made and modified by different thermal and mechanical treatments. The study and analysis of these samples was the objective of this inter-laboratory test (2nd. Round Robin Test) that involved researchers from the entire world.In the present study the processing of BN signals obtained from those samples was done. A detailed study, through the Root Mean Square function (RMS) applied to the BN signals, allowed a deeper and more detailed knowledge. These results were also compared with others previously obtained.
CYTOCHALASIN B AND PIGMENT GRANULE TRANSLOCATION : Cytochalasin B Reverses and Prevents Pigment Granule Dispersion Caused by Dibutyryl Cyclic AMP and Theophylline in Rana pipiens Melanocytes

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The redistribution of melanin granules within dermal and epidermal melanocytes of the frog is responsible for changes in skin color. Surviving frog skin can be lightened and darkened by many different compounds (I). When the granules are dispersed into the branched processes of individual melanocytes, the skin appears dark. When melanin granules are aggregated in the perikaryon, the melanocyte appears rounded or punctate by light microscopy and the skin is light. Melanocyte stimulating hormone (MSH) causes melanin granule dispersion, and an increase in cyclic adenosine 3, &apos;,5&apos;-monophosphate (cyclic AMP) in frog skin (2, 3). Cyclic AMP itself causes pigment granule dispersion; accordingly, it has been
LATE-BREAKING ABSTRACT: An algorithm for the identification of clinical COPD phenotypes in daily practice

Field: Medicine (Health Sciences)

Background: Several cluster analyses in cohorts of patients with chronic obstructive pulmonary disease (COPD) have identified possible clinical phenotypes, but their results have not been translated for use in daily practice. Objectives: To develop simple clinical rules for allocating COPD patients to specific phenotypes. Methods: Data from 2409 COPD patients from a French/Belgian COPD cohort were analysed using cluster analysis, resulting in the identification of phenotypes validated using all-cause mortality at 3 years. Classification and regression trees (CARTs) were used for developing a set of clinical rules for allocating patients to these phenotypes. The clinical value of this set of clinical rules was further examined in an independent sample of 3651 COPD patients from the COPD Cohorts Collaborative International Assessment (3CIA) initiative. Results: Five phenotypes of COPD patients with different respiratory characteristics, age, comorbidities, and 3-year mortality were identified. A set of clinical rules that included cardiovascular comorbidities and/or diabetes, forced expiratory volume in 1 sec, dyspnoea grade, and age and body mass index allowed accurate classification of approximately 80% of patients. External validation of these clinical rules was obtained in the 3CIA cohorts, in which they identified subgroups of patients with different clinical characteristics and prognosis. Conclusion: A simple set of rules using easily available clinical data may allow the identification of clinically relevant COPD phenotypes.
Complexes of 4-Hydroxyphenyltellurlum Trihalides with Piperidine, Dimethylformamide and Thiourea

Field: Chemistry (Physical Sciences)

Abstract New complexes of 4-hydroxyphenyltellurium trihalides with piperidine (Pip), dimethylformamide (DMF) and thiourea (Tu) have been synthesized and characterized by elemental analyses, conductance, cryoscopy, infrared and proton magnetic resonance spectral studies. RTeCI3. L as well as RTeCl3. 2L type complexes are obtained with all three ligands, whereas RTeBr3 and RTel3 form only 1:1 type complexes with DMF. The RTeCI3. 2Tu complex behaves as a non-electrolyte whereas the others are weak to 1:l electrolytes in solution. Spectral studies reveal the coordination through nitrogen, oxygen and sulphur atoms in piperidine, DMF and thiourea complexes, respectively.