jimnoneill/paper-to-field-training huggingface dataset:
Frequency Reconfigurable Antenna Using Infinity Complementary Split Ring Resonator for Wireless Communication

Field: Engineering (Physical Sciences)

In this paper, a frequency reconfigurable antenna using complementary infinity split resonator (CI-SSR) based metamaterial is designed and computing for wireless communication. The proposed antenna is printed in Rogers RT/ duroid 588O substrate having a dielectric constant (£r) of 2.2 within a size of 36. 56 × 36. 56 × 1. 57 mm3. By selecting a fed microstrip line, it is capable to achieve 50Q characteristic impedance and good impedance matching using quarter a wavelength transformer line. The parameter extraction procedure of the meta-material property of the I-SRR is discussed in detail, by which the negative permeability existence and the new resonance frequencies are verified. The proposed antenna has adequate advantages, including simple design, lower return loss and capable of frequency reconfigurable antenna using MADP-011029-14150 PIN diode.
Caterpillar Control on Tomato, 1977

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract The crop was seeded 10 May at O‘Neall Horticultural Farm, Lafayette, IN. Treatments were 1 row (60 in. centers) 25-ft in length separated from the next treated row by an untreated row. Treatments were arranged in a randomized complete block design with 4 replicates. Sprays were applied with a tractor-mounted hydraulic sprayer delivering 50 gpa at 80 psi through two D4-45 nozzles. Applications were made on 20 Jul, 13 Aug, 25 Aug, and 19 Sep. Second generation variegated cutworm did not appear in the plots in late July/Aug, nor did aphids build up as a result of the extremely wet weather. Worm damage was assessed at harvest by examining 100 fruit randomly per replicate. Fruit was hand harvested only once due to light set.
The Incorporation of Business Intelligence with Enterprise Resource Planning in SMEs

Field: Business, Management and Accounting (Social Sciences)

Enterprise Resource Planning (ERP) systems are essential tools for business innovation in small and medium-sized enterprises (SMEs), supporting almost all tasks, which allows to obtain large amounts of structured and unstructured data for future data analysis, which helps to facilitate decision making. Being portuguese business essentially composed of SMEs, it is important to invest in solutions that integrate decision making in ERPs, adapting them to change processes. Through literature review, such as conference articles and magazines, critical factors were defined that influence the choice of ERPs by SMEs, the benefits of incorporation with Business Intelligence that assumes a fundamental role in the current competitive environment and a comparison between several tools of BI.
Comparative electropherograms of muscle myogens of three Indian major carps.

Field: Agricultural and Biological Sciences (Life Sciences)

The present investigation reports muscle myogen patterns of Indian major carps viz. Catla catla, Cirrhinus mrigala and Labeo rohita collected from water bodies around Meerut. Using slab polyacrylamide gel electrophoresis, a comparative study of the separation patterns of protein bands in these species were carried out by preparing electropherograms. The band patterns of these species show inter specific variation and are species specific. The protein band pattern profile can be used as species specific marker. The three species studied differ from each other not only in terms of percentage relative mobility but also quantitatively (in number of bands) as well as qualitatively (in the intensity of bands).
A Subchronic Toxicity Study of Phosex 51B in Sprague-Dawley Rats

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Phos ex 51B is a ame retardant plasticizer that is blended with polyvinyl chloride lms to effectively control product ammabil-ity. Its composition places it in the butylated triphenyl phosphate category. Previous studies have shown Phos ex 51B to have low acute toxicity, to lack teratogenic and mutagenic activity, and to not induce delayed peripheral neuropathy. The present study was conducted to determine the toxicity of Phos ex 51B after repeated dietary exposure. Four groups, each consisting of 20 male and 20 female Sprague-Dawley rats, received rodent diet containing either 0, 100, 400, or 1600 ppm for 90 days. Parameters mea-sured includebodyweight, food consumption, clinical observations, hematology, clinical chemistry, and cholinesterase activity. Tissues were examined at necropsy for gross changes and were processed for microscopic pathology. There were no signi cant treatment-related effects on body weights, food consumption, hematology and clinical chemistry, or cholinesterase values. A signi cant in-crease was observed in the absolute and relative mean weights of livers in high-dose male rats, the mean relative liver weights of the high-dose female animals, the mean relative kidney weights of the high-dose male rats, and the mean absolute weights of the adrenal glands from high-dose female rats. Neither gross nor microscopic pathology examinations revealed tissue changes in these organs or in any other organs. Although increases in liver, kidney, and adrenal weights were observed in certain animals in the 1600-ppm high-dose group, the administration of Phos ex 51B did not result in signi cant treatment-related adverse effects at dietary dose lev-els of 100 and 400 ppm. The no-observable-effect level (NOEL) in this study is 400 ppm.
Comparative characterization of UDP‐glucuronic acid (UDP‐GlcUA) binding‐site directed inhibitors with human UGT2B7 and 1A10.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Recent crystallography, homology modeling, and mutagenesis studies of human UGTs have demonstrated that UGT2B7 and 1A10 possess a number of distinctive UDP‐glucuronic acid contact amino acids. We have investigated the specificity of these co‐factor binding sites further using 8 bi‐dentate inhibitors containing a lipophilic and a uridine moiety. K i and IC 50 values were calculated for PP55B and inhibition types were determined. Models of the UGT1A10 UDP‐GlcUA binding site were built using the crystal structure of the UGT2B7 C‐terminal domain as a template and using sequence homology to available structures of plant glucosyltransferases with the GT‐B folding motif. We have detected potential differences in the tertiary structure/function of the C‐terminal domain of these two isoforms and subsequently docked PP55B at the UDP‐GlcUA binding site in order to model inhibitor complexes for each enzyme, including its possible location with respect to the N‐terminal domain. Establishing the roles of individual UGT isoforms is important for UGT‐based drug discovery. The goal of theses studies is aimed at the identification of potent, selective UGT inhibitors, which could help to define these roles and provide the basis for the design of therapeutic agents. NIH‐DK60109, GM075893 (AR‐P)
Data from Long Noncoding RNA pancEts-1 Promotes Neuroblastoma Progression through hnRNPK-Mediated β-Catenin Stabilization

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

<div>Abstract<p>Long noncoding RNAs (lncRNA) play essential roles in tumor progression. However, the functions of lncRNAs in the tumorigenesis and aggressiveness of neuroblastoma still remain to be determined. Here, we report the identification of lncRNA <i>pancEts-1</i> as a novel driver of neuroblastoma progression by using a public microarray dataset. LncRNA <i>pancEts-1</i> promoted the growth, invasion, and metastasis of neuroblastoma cells <i>in vitro</i> and <i>in vivo</i>. Mechanistically, <i>pancEts-1</i> bound to hnRNPK to facilitate its physical interaction with β-catenin, whereas hnRNPK stabilized the β-catenin by inhibiting proteasome-mediated degradation, resulting in transcriptional alteration of target genes associated with neuroblastoma progression. Both <i>pancEts-1</i> and <i>hnRNPK</i> were upregulated in clinical neuroblastoma tissues, and were associated with unfavorable outcome of patients. Overall, our results define an oncogenic role of <i>pancEts-1</i> in neuroblastoma progression through hnRNPK-mediated β-catenin stabilization, with potential implications for the clinical therapeutics of neuroblastoma.</p><p><b>Significance:</b> These findings reveal the oncogenic functions of a long noncoding RNA in neuroblastoma progression, offering a potential target for clinical therapeutics. <i>Cancer Res; 78(5); 1169–83. ©2018 AACR</i>.</p></div>
Facework and linguistic politeness

Field: Arts and Humanities (Social Sciences)

Chapters 3 and 4 have outlined some of the major theoretical approaches to linguistic politeness in the literature and have discussed some of the criticisms of those approaches. The major criticism, centring on the dominant approach towards social structure evident in all the theories (an approach which Eelen (2001) calls Parsonian), will be dealt with in chapter 6. Before taking on that challenge, however, we need to develop an argument briefly mentioned in chapter 4:
Signalling and cellular memory for secondary metabolite production in Aspergillus nidulans

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Von Pilzen produzierte Sekundärmetabolite sind niedermolekulare und für diese überlebenswichtige Stoffe, die gleichzeitig die menschliche Gesundheit im Guten wie im Schlechten beeinflussen. Diese Doktorarbeit befasst sich mit der Regulation der Produktion von Sterigmatocystin (ST) im apathogenen Modellorganismus Aspergillus nidulans. Das Mycotoxin ST ist die vorletzte Vorstufe des Aflatoxins B1, einem der stärksten krebserregenden Stoffe der Natur. Durch den anthropogenen Klimawandel werden Kontaminationen von Lebens- und Futtermitteln durch Aflatoxine auch in Europa zunehmend zum Problem. Vor Beginn dieser Arbeit war nicht bekannt, unter welchen Bedingungen A. nidulans ST produziert, und die Literatur widersprüchlich. Wie bei den meisten Sekundärmetaboliten sind auch die für die Sterigmatocystinproduktion verantwortlichen Gene nachbarschaftlich zu Clustern zusammengefasst, wodurch sie koreguliert werden. Ich konnte nachweisen, dass die Abwesenheit einer Kohlenstoffquelle die Hauptbedingung darstellt, damit dieser Cluster aktiviert werden kann und habe einen neuen Regulator (RimO) beschrieben, der das Signal von der Umgebung der Pilzzelle an den Zellkern überträgt. Zusätzlich habe ich die Dynamik der transkriptionellen Cluster-Aktivierung mittels wiederholter Aktivierung (Gedächtnis) ebendieses untersucht und gezeigt, dass die Aktivierung beim zweiten Male beschleunigt ist. Die drei dafür verantwortlichen Faktoren sind 1. die Proteinstabilität des Cluster-spezifischen Transkriptionsfaktors (AflR), 2. ein unbekannter, löslicher Faktor im Überstand hungernder Kulturen des Pilzes und 3. die H3K4me2 Histonmodifikation. Diese Arbeit ist untrennbar mit Chromatinregulation verbunden, die die DNA der Cluster spatial öffnen kann und damit die Gene zugänglich für ihre Transkription macht. Diese Arbeit legt den Grundstein für die Identifizierung von Proteinen und Faktoren, die das Chromatin öffnen und wie die Produktion dieses Mykotoxins inhibiert werden kann.
Study finds why hospitals are failing to confront medical errors

Field: Health Professions (Health Sciences)

Researchers have identified why a model that helps to promote patients’ safety and reduce malpractice costs is not being more widely adopted by hospitals.

The University of Michigan Health System pioneered the three principle approach of “disclose, apologize, offer” more than a decade ago. The model proactively identifies unanticipated clinical outcomes, monitors their investigation and changes in practice, communicates with patients and manages remedial care, and offers compensation when warranted.

A new study published …
Prune and cherry brown-rot investigations in the Pacific Northwest /

Field: Agricultural and Biological Sciences (Life Sciences)

April and May, and less than 5 inches in the four months beginning with June and ending with September.The average monthly rainfall for July and August is less than three-fourths of an inch.Showery weather often prevails during the blooming season for prunes and cherries, but this is soon followed by relatively dry weather that usually continues through the cherry-picking period and sometimes well into the prune harvest.The weather conditions are thus rather unfavorable for the development of brown-rot, but they are not extreme enough to eliminate the disease.In most years brown-rot attracts but little attention, but occasionally it breaks into a serious epidemic that causes the loss of a large percentage of the crop.The destructive phases of the disease have taken two formsone an infection of the blossoms and the other a rotting of the fruit as it approaches maturity. BLOSSOM INFECTION.Blossom infection usually makes its first appearance as a browning or blackening of the under calyx lobes where drops of water have hung.In some cases it spreads down the pedicel, the fruit often turning back on its stem, while in others it confines itself largely to the petals and calyx, causing the young fruit to separate readily from its stem.The browned and blackened parts usually persist for a considerable time, furnishing a ready means of distinguishing the diseased blossoms from those that are yellowing from starvation or a lack of pollination.(PI.I, figs. 1, 2,46; Pl.II, A.) During the five years from 1915 to 1919, inclusive, when orchards were under close observation by the writers, blossom infection always occurred on both prunes and cherries.In each of these years counts of the infected and healthy blossoms were made on representative trees.The results are shown in Table 1.It will be seen that in some years the prune orchards were practically free from biossom infection, while in others from one-third to one-half of the young prunes were destroyed by brown-rot.The infection on the sweet cherries was even more serious than on the prunes.This subject will be given further consideration under headings relating to plowing, cultivation, and spraying.TABLE 1.-Count of blossoms infected with brown-rot on representative prune and cherry trees.Percent-Percent-Year. Variety and location.age Year.| ' Variety and
A Collision Detection System for a Mobile Robot Inspired by the Locust Visual System

Field: Computer Science (Physical Sciences)

The lobula giant movement detector (LGMD) is an identified neuron in the locust brain that responds most strongly to the image of an approaching object such as a predator. A computational neural network model based on the structure of the LGMD and its afferent inputs is also able to detect approaching objects. In order for the LGMD network to be used as a robust collision detector for robotic applications, we proposed a new mechanism to enhance the feature of colliding objects before the excitations are gathered by LGMD cell. The new model favours grouped excitation but tends to ignore isolated excitation with selective passing coefficients. Experiments with a Khepera robot showed the proposed collision detector worked in real time in an arena surrounded with blocks.
Tissue Culture Studies of the Virus of Progressive Pneumonia, A Slow Infectious Disease of Sheep

Field: Veterinary (Health Sciences)

Properties of progressive pneumonia virus (PPV) were studied in sheep lung cell monolayers. Growth studies revealed that, with a multiplicity of infection of 2 TCID50 virus/cell, virus replicated to a titer of 106.6 TCID50 virus/ml in 4 days. Typical polykaryocytes were first seen at 1 day post inoculation (PI) and became larger and more numerous as the virus titer increased. Inoculation of high concentrations of virus produced cell fusion within 3 hr PI. Indirect immunofluorescence revealed homogeneous cytoplasmic fluorescence in infected cells as early as 1 day PI. The number of cells showing fluorescence and the intensity of the fluorescence increased steadily with increase of virus titer. The genetic material for PPV is probably single-stranded RNA. The various properties indicate that PPV is closely related to maedi, zwoegerziekte, and visna viruses.
Millennials and Generation Z: Challenges and Future Perspectives for International Tourism

Field: Social Sciences (Social Sciences)

This issue of the Journal of Tourism Futures examines the future of tourism through generational lenses. This special issue concentrates upon the relationship between the Millennial Generation, Gen Z members and Tourism. The generational shift represents a major force that will shape the future of tourism. The eight articles included in the special issue – written by senior and junior leading scholars from different countries – present unique studies to explore the ways Millennials and Gen Z members are influencing tourism in Asia, Europe, the USA. By using a variety of ‘qualitative’ and ‘quantitative’ methods, the authors address a number of issues: implications on tourism of changing expectations and behaviours between the two Generations; if and how Millennials and Gen Zers care about sustainable tourism; the relationship between technology and tourism; how the tourism industry should prepare for the generational shift
A Bargaining Theory of Criminal War

Field: Social Sciences (Social Sciences)

Abstract Criminal war is a leading cause of death around the world. We argue for the inclusion of this topic in security studies and adapt a bargaining framework to shed light on why criminal groups fight or agree to peace. We propose that shocks to relative coercive capacity cause criminal war. This escalation in violent conflict proves more likely when criminal groups face greater difficulty negotiating: when they are more factionalized, less rooted in their territory, and in strategic rivalry with a greater number of rivals. Our empirical strategy leverages a critical, policy-relevant shock to access to weapons following an arms control repeal, and novel city block-level, monthly data on criminal organization traits, turf, and violence over ten years to understand how changes in coercive inputs upset the existing balance of power among criminal groups and shaped patterns of war and truce.
Malaysia urges ASEAN to tackle AIDS crisis.

Field: Health Professions (Health Sciences)

Urgent action is needed to fight the alarming spread of HIV/AIDS that infected 1.3 million people in Southeast Asia last year alone, Malaysia's foreign minister said July 24, 2000. Syed Hamid said the Association of Southeast Asian Nations (ASEAN) should tackle at regional and national level an epidemic that was taking its most drastic toll among the region's youth. "HIV/AIDS not only represents a major public health and social problem but is a serious challenge to development as well," Syed Hamid told the opening ceremony of ASEAN's 33rd annual foreign ministers' meeting. The crisis requires commitment at the "highest political level," he said, warning that HIV/AIDS could become a transnational problem within the 10-member group. Foreign ministers have recommended their leaders discuss the crisis later this year at an informal summit in Singapore and hold a summit on HIV/AIDS in conjunction with the 7th ASEAN Summit in Brunei next year. "I think people recognized the importance and the adverse impacts on our social development," Syed Hamid told reporters later. "I think it is a real issue that we cannot run away from." Among ASEAN members, Thailand, Cambodia, and Myanmar have some of the highest infection rates in Asia of HIV, the virus that causes AIDS.
are gene arrays useful for the study of implantations?

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

This chapter reviews how microarray studies to date have advanced understanding of critical aspects of the biology of implantation and discusses potential applications in the future. All gene arrays for expression profiling depend on hybridisation of complementary strands of DNA or RNA. Progesterone receptor (PR) has long been known to be essential for the preparation of a receptive endometrium, until now relatively little has been known about the molecular pathways regulated by progesterone in the endometrium. One of the novel genes upregulated by progesterone is the lipid-metabolising enzyme leucocyte 12/15-lipoxygenase. In women, the action of the progesterone receptor is also essential for the development of receptivity, which occurs between day luteinising hormone (LH)+5 and day LH+10. The ability of microarrays to analyse thousands of mRNAs simultaneously provides a powerful new approach to the identification of markers of receptivity.
Preliminary phytochemical and in-vitro pharmacological evaluation of whole plant extracts of Ziziphus nummularia Burn. f.

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The aim of the present study is to evaluate the in-vitro pharmacological activities of various fractions of hydroalcoholic extracts of Ziziphus nummularia Burn. f. The anti-inflammatory activity was performed by heat induced haemolysis, membrane stabilization and protein denaturation inhibition assay. Diclofenac sodium was used as standard drug. The immunomodulatory activity was carried out on human neutrophils by assessing nitrobluetetrazolium test, neutrophil locomotion and chemotaxis. All the extracts were tested at concentrations viz. 100, 250, 500 and 1000 μg/ml. The various extracts showed significant activity on in vitro human neutrophils and protein denaturation which are comparable to standard and control at different concentration indicating the possible immune-stimulating, anti-inflammatory and antimicrobial effect.
Tannic Acid-Based Biomimetic Nanomedicine with Pathological Reactive Oxygen Species-Responsive Cargo Release for Relieving Inflammation in Rheumatoid Arthritis

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Rheumatoid arthritis (RA) is a chronic disease characterized by immune cell infiltration and cartilage damage. The local lesion of RA shows severe oxidative stress and proinflammatory cytokine secretion. For drug therapy, the efficacy of agents, such as methotrexate (MTX), may be greatly limited, resulting from the low bioavailability, immune clearance, and toxic side effects. A nanocarrier (TA-PBA NPs) was developed with anti-inflammatory and antioxidant activities, combined with MTX to prepare nanomedicine (MTX NPs) for synergistic treatment of RA. Moreover, inspired by the biological functions homing to inflammation lesion of macrophages, the biomimetic nanomedicine camouflaged with macrophage membrane (MM@MTX NPs) was constructed. TA-PBA NPs could timely promote MTX release in response to the overaccumulated ROS to exhibit high anti-inflammatory and antioxidant activities for alleviating RA progression. The experimental results confirmed that MM@MTX NPs could significantly reduce the secretion of proinflammatory cytokines (TNF-α) while significantly increasing the typical anti-inflammatory cytokines (IL-10), promote the phenotype transformation of macrophages from M1 to M2, and up-regulate the Nrf2-keap1 pathway-related proteins (HO-1 and NRF2) to positively regulate the local inflammation for effectively inhibiting RA development. Thus, MM@MTX NPs represent a possible candidate as a safe and efficient nanotherapy platform for RA management.