jimnoneill/paper-to-field-training huggingface dataset:
Apoptotic Microrna Profiling of Packed Red Blood Cells During Storage.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Abstract 3145 Poster Board III-82 Introduction During storage, RBCs undergo physiological changes often termed as storage lesions that adversely affect their survival in vivo, following transfusion. MicroRNAs (miRs), the negative regulators of cellular mRNAs, control cellular expression of genes relevant to differentiation and apoptosis via mRNA degradation or inhibition of translation. Recent reports indicate that matured red blood cells (RBC) contain diverse population of miRs in abundance. Understanding the role of miRs in RBC during storage would perhaps provide insights into the mechanisms associated with storage lesions. Methods In this study, we utilized a membrane-based array to obtain differential miR profiles of 52-apoptosis-associated miRs in packed RBCs during storage. The packed RBCs were obtained from the National Institutes of Health (NIH) blood bank and stored at appropriate storage condition (4-8°C) for up to 40 days. Samples were collected at days 0, 10, 20, 30 and day 40 and subjected to miR analysis. Our rationale is that since miRs are regulators of apoptosis, profiling of apoptosis associated miRs in packed RBCs during storage would provide the first step towards understanding the underlying mechanisms associated with storage lesions. Results Our miR analysis identified perturbation of six miRNAs during packed RBC storage. Two miRs remain at high levels throughout the RBC storage period studied while four miRs demonstrated an upward trend from day 0 to day 40 of storage. TarMir bioinformatics-based target gene identification for miR-96 identified CASPN1 mRNA as its target. The presence of CASPN1 mRNA was confirmed by RT-PCR. Although this observation tempts us to speculate that an interaction of CASPN1 with miR-96 in stored RBC is possible, further experimental verification of this interaction is warranted. Conclusion The differential microarray analysis presented here suggest that further refinement of miR profiling of stored red blood cells could be of value as predictive markers of ‘cellular status of RBC’ during storage. Future experimental analysis of selected mRNA-miR interactions in packed RBC during storage would provide insights into the mechanisms of storage lesions The findings and conclusions in this abstract have not been formally disseminated by the Food and Drug Administration and should not be construed to represent any Agency determination or policy. Disclosures No relevant conflicts of interest to declare.
Prospects of Women Construction Workers in Tamil Nadu, South India

Field: Social Sciences (Social Sciences)

The construction sector is one of the largest employers of women next to agriculture in India. This article analyses the data from a large sample of men and women construction workers, and proposes ways to empower women workers. Most of them are very poor and destitute, face harassment at both home and workplace and do the heaviest work. This study suggests training for women as masons to equalise their opportunities.
Adolescents in various contexts during the COVID‐19 pandemic: A commentary

Field: Social Sciences (Social Sciences)

Abstract This commentary provides a reflection on the impact of the COVID‐19 pandemic on adolescents in the context of family dynamics, school environments, peer relationships, and civic engagement. Drawing from four systematic literature reviews, the commentary highlights key findings, such as the long‐term effects of COVID‐19 on adolescent development, mental health, and academic well‐being. The need for future research is emphasized to assess how these cohort effects will evolve over time. Cultural context and socioeconomic disparities emerge as crucial considerations, with the pandemic exacerbating existing inequalities, especially in access to education and digital resources. This commentary also underscores the importance of adopting a socio‐ecological perspective to understand the multifaceted impact of COVID‐19 on adolescents globally. In conclusion, it calls for targeted policies to support adolescents' mental health and academic recovery post‐pandemic, particularly in underserved communities. Governments, educators, and civic organizations are encouraged to create inclusive policies that address these disparities while fostering resilience and well‐being among young people. These reviews may also inform translational research that could aid in the development of evidence‐based interventions and policies aimed at helping adolescents thrive in a post‐pandemic world.
A new rock dwelling frog of the genus Eleutherodactylus (Amphibia: Leptodactylidae) from Eastern Cuba, with comments on other species with similar habits

Field: Agricultural and Biological Sciences (Life Sciences)

A new species of the genus Eleutherodactylus (subgenus Euhyas) is described from the limestone region at the north slope of the Sierra Maestra, Eastern Cuba. It is a large, rock dwelling species with enlarged digital discs and mottled dorsum. It closely resembles E. bresslerae, differing from it by a combination of external characters, chromosome patterns, and vocalization. Comparisons are also made with E. ricordii, E. acmonis, and some other Cuban members of the genus that share similar habits.
OPTIMIZING CARTON PRODUCT DELIVERY BY SOLVING TRAVELLING SALESMAN PROBLEM AT PACKAGING COMPANIES

Field: Decision Sciences (Social Sciences)

Optimization of delivery routes is one form of increasing business productivity to achieve the company's main goal of distributing each product to customers. The Traveling Salesman Problem (TSP) is a combinatorial optimization problem where a salesman goes on a distribution journey that starts from the depot, then visits all customers exactly once, and ends with returning to the depot. This study aims to optimize the distribution route of carton products for packaging companies using the TSP model. The research methodology includes observation, interviews, and document studies to understand the distribution process of carton products at packaging companies. To complete the TSP model, Branch and Bound (BB) and Nearest Neighbor (NN) methods are applied to find the best solution for determining the distribution route of carton products. The way the BB method works is by utilizing branch cuts and boundaries to reduce search space and speed up the resolution process. In the NN method, the nearest point is chosen to get the shortest route distance. Research findings show that the use of the BB method results in a mileage difference from the initial route of 125 km (53% more efficient) and a fuel cost difference of 121,231 IDR (45% cheaper). Meanwhile, the NN method results in a mileage difference from the initial route of 115 km (48.94%) and a fuel cost difference of 109,901 IDR (41.27%). So, the method that produces the best solution is the BB method. The limitations of this study lie in the scale of the model used and the assumptions underlying the analysis. Future research can broaden the scope of the model and consider other factors that may affect the distribution of carton products. The results of this study contribute to improving the efficiency of carton product distribution.
On Laplacian energy of picture fuzzy graphs in site selection problem

Field: Mathematics (Physical Sciences)

In the present work, the adjacency matrix, the energy and the Laplacian energy for a picture fuzzy graph/directed graph have been introduced along with their lower and the upper bounds. Further, in the selection problem of decision making, a methodology for the ranking of the available alternatives has been presented by utilizing the picture fuzzy graph and its energy/Laplacian energy. For the shake of demonstrating the implementation of the introduced methodology, the task of site selection for the hydropower plant has been carried out as an application. The originality of the introduced approach, comparative remarks, advantageous features and limitations have also been studied in contrast with intuitionistic fuzzy and Pythagorean fuzzy information.
Experimental and Clinical Studies of Phonocardiogram : Effects of the Changes of Preceding R-R Interval and Intraventricular Conduction on First and Second Heart Sound.

Field: Medicine (Health Sciences)

There have been many contraversies or disputes concerning to the hemodynamic mechanism of the development of the first sound and splitting of the second sound. Still many arguments are present whether the first heart sound is developed simply by the vibratory movements of the valvular leaflets or with cardiac muscular tonic vibration. It has been well known that the prolonging diastasis increases the filling volume from atria to ventricle which may affect the modes of ventricular isometric contraction and also the ventricular premature beats, either induced experimentally or clinically, interrupt any points of the time during diastasis and may result in abnormally delayed intraventricular conduction. The purpose of this paper is to study the hemodynamic mechanism for the development of first and second heart sound in case with variable R-R interval because of the occur rences of vent.ricular premature beats induced experimentally in dogs by mechanical or electrical stimulation to the both ventricles or in clinical cases. A) The author has studied the Q-I time, amplitude and splitting of Ist soundin a series of dogs with experimentally induced premature ventricular contractions, as mentioned about. Q-I time equivocally prolonged which has been attributed to the effects of electrical as well as mechanical delay of the onset of ventricular contraction. Succeeding isometric contraction period also prolonged. The amplitude of the Ist sound appeared to show positive correlation to the preceding diastolic period, which also suggested the presence of positive correlation between the amplitude of Ist sound and ventricular filling volume. In case with extreme short preceding R-R interval, the amplitude of Ist sound was significantly reduced and the succeeding ventricular ejection was failed to take place. These observations suggest cooperated action between vibrations of valvular leaflet and myocardial tonic vibration in establishing the Ist heart sound.
Efficient Deep Learning Methods for Automated Visibility Estimation at Airports

Field: Computer Science (Physical Sciences)

The goal of this paper is to design and develop new visibility estimation methods for airports based on deep neural networks. Their input consists of partially annotated image meteorological data, especially camera images from automatic meteorological stations. These have been processed, normalized, cleaned, and annotated according to meteorological observation codes and geographic data, with manually entered values. We have experimented with different methods of image processing, leveraging deep learning in order to find and finetune a lean, yet effective neural network architecture capable of providing the desired visibility estimation quality.
(Re)Integration of mental patients - mixed media messages.

Field: Social Sciences (Social Sciences)

It can be said that (re)integration of mental patients is the basic goal of psychiatry as a medical discipline. Throughout the history of psychiatry different approaches to treatment and rehabilitation of mental patients and their social (re)integration have been identified and monitored. There have always existed different impediments to the (re)integration of mental patients, as a manifestation of the times when treatment and rehabilitation took place. In the beginning of psychiatric development, the principal goal, in line with the social development and social awareness of human rights, was to isolate the patient away from his/her social environment and place him/her into a psychiatric hospital, preferably for life. Lately, as fighting for human rights grew into a matter of fashion and prestige rather than an ethical and legal issue, the media have often spoken about the human rights of mental patients and, explicitly or implicitly, advocated their social (re)integration. This cry for human rights of mental patients has virtually rooted out the advocates for permanent social isolation, even in this region. However, the Croatian media often give out the so called mixed messages when it comes to treating mental patients. This article analyzes such contradictory communication and attempts to offer certain solutions.
Instrumentation Requirements for the Engineering Evaluation of Nuclear-Electric Spacecraft

Field: Engineering (Physical Sciences)

Spacecraft employing nuclear-electric propulsion are being proposed for missions to Venus and distances beyond. These spacecraft utilize a nuclear reactor to provide thermal energy to a turboalternator which generates electric power for an ion motor and the other spacecraft systems. This Report discusses the instrumentation and communications system needed to evaluate a nuclear-electric spacecraft in flight, along with the problems expected. A representative spacecraft design is presented, which leads to a discussion of the instrumentation needed to evaluate such a spacecraft. A basic communications system is considered for transmitting the spacecraft data to Earth. The instrumentation and communications system, as well as all electronic systems on a nuclear-electric spacecraft, will be operating in high temperature and nuclear-radiation environments. The problems caused by these environments are discussed, and possible solutions are offered.
Emirati Women: Generations of Change by Jane Bristol-Rhys

Field: Social Sciences (Social Sciences)

Book Review| July 01 2013 Emirati Women: Generations of Change by Jane Bristol-Rhys Emirati Women: Generations of Change, Bristol-Rhys, Jane. New York: Columbia University Press, 2010. 145 pages. ISBN 978-0-231-70204-1. Tabitha Decker Tabitha Decker Yale University Search for other works by this author on: This Site Google Journal of Middle East Women's Studies (2013) 9 (2): 116–119. https://doi.org/10.2979/jmiddeastwomstud.9.2.116 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Permissions Cite Icon Cite Search Site Citation Tabitha Decker; Emirati Women: Generations of Change by Jane Bristol-Rhys. Journal of Middle East Women's Studies 1 July 2013; 9 (2): 116–119. doi: https://doi.org/10.2979/jmiddeastwomstud.9.2.116 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsJournal of Middle East Women's Studies Search Advanced Search The text of this article is only available as a PDF. Copyright © 2013 Association for Middle East Women’s Studies2013 Article PDF first page preview Close Modal Issue Section: Book Reviews You do not currently have access to this content.
Effect of compound probiotics and yeast culture on milk production, rumen fermentation and serum anti-stress parameters of heat-stressed dairy cows

Field: Agricultural and Biological Sciences (Life Sciences)

This study aimed to evaluate the effect of newly developed compound probiotics on milk production, rumen fermentation characteristics and serum anti-stress parameters of heat-stressed dairy cows. Forty-five late-lactation dairy cows were randomly allocated into three groups, including control group (basal total mixed ration, TMR), compound probiotics (CP) group (20 g/d compound probiotics per cow in TMR) and yeast culture (YC) group (100 g/d yeast culture per cow in TMR). The results indicated that the compound probiotics and yeast culture increased milk yield significantly (P=0.03) with no influence on milk content, and improved ammonia nitrogen and microbial protein concentrations in rumen fluid (P=0.04) with no influence on volatile fatty acid concentration. The compound probiotics and yeast culture enhanced the apparent digestibility of crude protein and neutral detergent fiber (P<0.05), and a better performance was observed in the compound probiotic groups. The compound probiotics and yeast culture increased serum triiodothyronine (T3) content significantly (P<0.01). Thus, the compound probiotics could alleviate the negative effect of heat stress on dairy cows, and perform better than the yeast culture.
O-184 Obesity Level Related To Clustering Of Risk Factors For Cvd

Field: Medicine (Health Sciences)

<sec><st>Background and aims</st> Obesity is associated with increased risk of cardiovascular disease (CVD) in adults. We assessed if body fat and abdominal fat are related to clustering of risk factors for CVD in younger children. </sec> <sec><st>Methods</st> Cross-sectional study of 170 (92 boys and 78 girls) children aged 8–11 years, recruited from a population-based cohort. Total fat mass (TBF) and abdominal fat (AFM) were measured by DXA. Total body fat was expressed as TBFs percentage of total body mass (BF%). Maximal oxygen uptake (VO<inf>2PEAK</inf>)was measured by indirect calorimetry. Blood was sampled and blood pressure (BP), and resting heart rate (HR) were measured and pulse pressure (PP) was calculated. Echocardiography was performed and left atrial diameter (LA) was measured, and left ventricular mass (LVM) and relative wall thickness (RWT) were calculated. Z-scores (Value for the individual-mean value for group)/SD) were calculated. Sum of z-scores for triglycerides and lipoprotein concentrations, systolic and diastolic BP, PP, HR, LVM, LA, RWT and -VO<inf>2PEAK</inf> were calculated in boys and girls, separately, and used as an indices of clustered risk. </sec> <sec><st>Results</st> Pearson correlations between ln BF% and ln AFM versus indices of clustered risk were in boys (r = 0.58 and 0.59, p < 0.05), and in girls (r = 0.58 and 0.64, p < 0.05). One-way ANOVA analysis indicated significant differences between different tertiles of BF% and AFM. Higher BF% and AFM were associated with higher clustered risk for CVD in both genders (p < 0.001). </sec> <sec><st>Conclusions</st> Both total body fat and abdominal fat were associated with a clustering of CVD risk factors. </sec>
Low complexity algorithm for the extraction of vehicular traffic variables

Field: Computer Science (Physical Sciences)

We present an alternative technique for acquisition of traffic variables, using less computer resources and less processing time, by using a computer vision algorithm that process only non redundant information. The algorithm allows estimating vehicular mean speed and vehicular volume in 2 or 3 lanes roads. It distinguishes vehicles from the background using a single line of the image and estimates the mean speed of the vehicles by using two lines of the image. This minimizes both, the quantity of information that has to be processed, and the total processing time. The algorithm also uses a spatio-temporal transformation, allowing more time for the detection process, therefore reducing hardware requirements.
Analysis of the Higher Education Act Reauthorizations: Financial Aid Policy Influencing College Access and Choice

Field: Social Sciences (Social Sciences)

The original goal of the Higher Education Act of 1965, the amendments to that act in 1972, and reauthorizations through 1998 was to increase accessibility of higher education to all. Initially these system-level efforts substantially enhanced equity, but recent enrollment trends raise the question: Is our system becoming more or less equitable? By conducting a policy analysis of the HEA reauthorizations and other legislation, in respect to policy decision-making and policy implementation on federal and state levels, this paper examines how financial aid policy influences college access and choice for low- to moderate-income undergraduate students. Key elements in the federal policy process are examined and recommendations for future state policy are addressed.

Keywords: higher education, financial aid, public policy, access, choice, equity
Randomised controlled trial of WISENSE, a real-time quality improving system for monitoring blind spots during esophagogastroduodenoscopy

Field: Medicine (Health Sciences)

Objective Esophagogastroduodenoscopy (EGD) is the pivotal procedure in the diagnosis of upper gastrointestinal lesions. However, there are significant variations in EGD performance among endoscopists, impairing the discovery rate of gastric cancers and precursor lesions. The aim of this study was to construct a real-time quality improving system, WISENSE, to monitor blind spots, time the procedure and automatically generate photodocumentation during EGD and thus raise the quality of everyday endoscopy. Design WISENSE system was developed using the methods of deep convolutional neural networks and deep reinforcement learning. Patients referred because of health examination, symptoms, surveillance were recruited from Renmin hospital of Wuhan University. Enrolled patients were randomly assigned to groups that underwent EGD with or without the assistance of WISENSE. The primary end point was to ascertain if there was a difference in the rate of blind spots between WISENSE-assisted group and the control group. Results WISENSE monitored blind spots with an accuracy of 90.40% in real EGD videos. A total of 324 patients were recruited and randomised. 153 and 150 patients were analysed in the WISENSE and control group, respectively. Blind spot rate was lower in WISENSE group compared with the control (5.86% vs 22.46%, p<0.001), and the mean difference was −15.39% (95% CI −19.23 to −11.54). There was no significant adverse event. Conclusions WISENSE significantly reduced blind spot rate of EGD procedure and could be used to improve the quality of everyday endoscopy. Trial registration number ChiCTR1800014809; Results.
Occurrence Download

Field: Agricultural and Biological Sciences (Life Sciences)

A dataset containing 2 species occurrences available in GBIF matching the query: { "Geometry" : [ "POLYGON ((149.162269 -33.992946, 149.162269 -33.999683, 149.164515 -33.999683, 149.164515 -33.995191, 149.16676 -33.995191, 149.16676 -33.992946, 149.162269 -33.992946))" ] } The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0059703-240626123714530/datasets/export for details. Data from some individual datasets included in this download may be licensed under less restrictive terms.
TrustZero -- open, verifiable and scalable zero-trust

Field: Computer Science (Physical Sciences)

We present a passport-level trust token for Europe. In an era of escalating cyber threats fueled by global competition in economic, military, and technological domains, traditional security models are proving inadequate. The rise of advanced attacks exploiting zero-day vulnerabilities, supply chain infiltration, and system interdependencies underscores the need for a paradigm shift in cybersecurity. Zero Trust Architecture (ZTA) emerges as a transformative framework that replaces implicit trust with continuous verification of identity and granular access control. This thesis introduces TrustZero, a scalable layer of zero-trust security built around a universal "trust token" - a non-revocable self-sovereign identity with cryptographic signatures to enable robust, mathematically grounded trust attestations. By integrating ZTA principles with cryptography, TrustZero establishes a secure web-of-trust framework adaptable to legacy systems and inter-organisational communication.