jimnoneill/paper-to-field-training huggingface dataset:
¿Las TIC como mediadoras en la enseñanza-aprendizaje de lenguas extranjeras?

Field: Arts and Humanities (Social Sciences)

This article analyzes from the point of view of the student the technological\nresources at the University, as well as the engagement of teachers\nin the pedagogical proposals using ICT, those that motivate more students.\nRegarding the methodology this study is based on the qualitative\nanalysis of a questionnaire. One of the results of the study is that the use\nof ICT has a very positive impact in the student and consequently demonstrates\nthe importance of the University educational system’s involvement\nin raising the standards of quality teaching through the use of ICT\nin the teaching/learning of language.
A closed formula for calculating pesticide residue levels in the feed items of terrestrial species

Field: Environmental Science (Physical Sciences)

Abstract Calculating pesticide residue levels in feed items for terrestrial species requires accounting for the application rate of the pesticide, the frequency and interval of application, the half-life of the pesticide on the food item, and the residue unit dose. Microsoft Excel™–based applications such as the US Environmental Protection Agency's Terrestrial Residue Exposure model (T-REX) and Terrestrial Herpetofaunal Exposure Residue Program (T-HERPS) calculate the residue levels in feed items using a recursive sequence. A recursive sequence is an unwieldy calculation method that presents a barrier to creating a software-based tool capable of conducting flexible assessments. Therefore, we determined the closed form of the recursive mathematical equation used by both T-REX and T-HERPS. With this formula, we can both duplicate screening-level assessments (T-REX, T-HERPS) as well as incrementally refine the assessment with data-driven inputs. Integr Environ Assess Manag 2018;14:703–709. © 2018 SETAC Key Points We determined the closed form of the recursive mathematical equation used by both the Terrestrial Residue Exposure model (T-REX) and the Terrestrial Herpetofaunal Exposure Residue Program (T-HERPS). With this formula, applications can be created that use data-driven inputs not currently allowed by T-REX or T-HERPS.
Treatment of Established Nonunions of Mitchell Osteotomies

Field: Medicine (Health Sciences)

The Mitchell distal metatarsal stepcut osteotomy for the treatment of hallux valgus is a technically demanding procedure with a high complication rate. Reported com-plications include metatarsal shortening with lateral metatarsalgia, partial avascular necrosis of the distal fragment, and loss of position with incomplete correc-tion. Nonunion, however, has only rarely been reported. We describe our experience with the treatment of three nonunions of Mitchell osteotomies reconstructed using a tricortical iliac crest bone graft.
Abstract A102: Association of lymphoid malignancies and area-based socioeconomic status with survival in the United States

Field: Medicine (Health Sciences)

Abstract Background: Over 114,000 new cases of lymphoid malignancies (LM), including Hodgkin lymphoma (HL), Non-Hodgkin lymphoma (NHL) and multiple myeloma (MM), are diagnosed annually. However, little is known about the influence of socioeconomic status (SES) on LM survival among Hispanics, who comprise 18% of the US population. This study evaluates the association between area-based SES and survival of Hispanic LM patients compared with non-Hispanic whites and non-Hispanics blacks. Methods: All LM reported to the NCI Surveillance, Epidemiology, and End Results Program (SEER-18) diagnosed between 2000-2015 were included. Census tract-level socioeconomic status (SES) was assessed in tertiles. Cox proportional hazards models estimated hazard ratios (aHR) to evaluate SES with cause-specific survival, adjusted for sex, stage at diagnosis, radiation, surgery and chemotherapy. All analyses were stratified by race/ethnicity. Results: Hispanics with low SES diagnosed with MM were 30% (aHR:1.3, 95% CI: 1.0-1.6) more likely to die from MM than those Hispanics with high SES. Whites and blacks with low SES diagnosed with MM were 20% (95% CIwhites: 1.1-1.3; 95% CIblacks: 1.0-1.4) more likely to die from MM than those with high SES. An association of low SES and death from NHL also found among Hispanics (aHR: 1.2; 95% IC: 1.1-1.5), whites (aHR: 1.3; 95% IC: 1.2-1.4) and blacks (aHR: 1.3; 95% IC: 1.0-1.7) compared to high SES groups. No association was found for HL. Conclusion: Low SES was associated with worse LM survival among different races/ethnicities. These results suggest SES is an important factor in determining long-term outcomes of patients diagnosed with LM. Citation Format: Maira A Castaneda-Avila, Bill Jesdale, Mara Epstein. Association of lymphoid malignancies and area-based socioeconomic status with survival in the United States [abstract]. In: Proceedings of the Twelfth AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2019 Sep 20-23; San Francisco, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2020;29(6 Suppl_2):Abstract nr A102.
Revision of the Australian Coccinellidae (Coleoptera). Genus <I>Diomus</I> Mulsant. Part 1

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract. The first paper dealing with revision of the Australian members of cosmopolitan genus Diomus Mulsant treats 30 species, mostly with distinct colour pattern, that can be identified using external characters. Nomenclatural history, diagnoses, illustrations and distribution are provided for each species. Fifteen new species are described: Diomus ancorus sp. nov., D. bimaculatus sp. nov., D. brookfieldi sp. nov., D. capital sp. nov., D. kuranda sp. nov., D. kosciuszko sp. nov., D. millaamillaa sp. nov., D. marmorosus sp. nov., D. ningning sp. nov., D. reidi sp. nov., D. storeyi sp. nov., D. tinaroo sp. nov., D. torres sp. nov., D. weiri sp. nov., D. zborowskii sp. nov.. The following new synonyms are proposed: Diomus sphragitis (Weise, 1885) = Scymnus trilobus Lea, 1902 = Scymnus indistinctus Lea, 1902; Diomus sydneyensis (Blackburn, 1892) = Scymnus mimicus Lea, 1902 = Scymnus pectoralis Lea, 1902 (new synonyms). Scymnus australis Blackburn, 1889 is transferred to Diomus (new combination). Lectotypes are designated for the following taxa: Diomus rusticus Weise, 1859; Scymnus australis Blackburn, 1889; S. corticalis Lea, 1908; S. cucullifer Blackburn, 1892; S. ementitor Blackburn, 1895; S. flavifrons Blackburn, 1889; S. flavolaterus Lea, 1926; S. indistinctus Lea, 1902; S. jocosus Blackburn, 1892; S. kamerungensis Blackburn, 1895; S. meyricki Blackburn, 1889; S. mimicus Lea, 1902; S. notescens Blackburn, 1889; S. pectoralis Lea, 1902; S. (D.) pumilio Weise, 1885; S. (D.) scapularis Weise, 1885; S. striatus Lea, 1902; S. sydneyensis Blackburn, 1892; S. tenebricosus Boheman, 1859 and S. trilobus Lea, 1902.
Health and Safety Regulations for COVID-19: A Policy Analysis

Field: Social Sciences (Social Sciences)

Abstract The COVID-19 pandemic spurred some regulators in the USA to require occupational health and safety programs to prevent COVID-19 transmission in workplaces. The objective of this study was to describe such state and federal regulations enacted between January 2020 and January 2022. Regulations, including emergency temporary standards (ETS) and permanent standards, were identified through a search of Nexis Uni and Bloomberg Law and review of US OSHA websites and the Federal Register. Full texts were reviewed for regulatory scope, hazard and exposure definitions, determination of exposure or risk levels, and control strategies. Four state (California, Michigan, Virginia, and Oregon) and two federal regulations were identified. All regulations described respiratory aerosols as the primary source of SARS-CoV-2 and recognized person-to-person transmission by droplet, airborne, and contact routes. Only the US OSHA ETS for healthcare explicitly stated that inhalation of respiratory particles was the most likely method of COVID-19 transmission. The Virginia, Michigan, and Oregon regulations described different categories of risk defined by exposure frequency and duration or specific workplace activities. California described exposure as places and times when employees come into contact or congregate with other people. The US OSHA ETS for healthcare described exposure as involving close contact with suspected or confirmed COVID-19 patients. While all of the state regulations required strategies from across the hierarchy, only the Virginia regulations specifically incorporated the hierarchy of controls. Only the California and Virginia regulations explicitly linked control strategies to the transmission route, while Virginia demarcated control strategies by risk level. Oregon linked risk level to occupancy levels and physical distancing requirements and referred to the use of a layered approach for transmission control. The US OSHA ETS for healthcare defined droplet and airborne precautions but made no mention of the hierarchy of controls or risk levels. Respirators were discussed in most of the regulations. The first Michigan regulation explicitly required respirators appropriate to exposure risk. The California regulations noted that respirators protect the wearer while face coverings protect people around the wearer. These regulations offer insights for a permanent US OSHA infectious disease regulation, such as the need to consider a range of transmission modes including near- and far-range aerosol inhalation, endemic and novel pathogens, workplaces beyond healthcare settings, factors that contribute to exposure and risk, the hierarchy of controls, the role of vaccination, and the importance of written exposure assessment and infection prevention plans.
Improved Evaluation Framework for Complex Plagiarism Detection

Field: Computer Science (Physical Sciences)

Plagiarism is a major issue in science and education. Complex plagiarism, such as plagiarism of ideas, is hard to detect, and therefore it is especially important to track improvement of methods correctly. In this paper, we study the performance of plagdet, the main measure for plagiarim detection, on manually paraphrased datasets (such as PAN Summary). We reveal its fallibility under certain conditions and propose an evaluation framework with normalization of inner terms, which is resilient to the dataset imbalance. We conclude with the experimental justification of the proposed measure. The implementation of the new framework is made publicly available as a Github repository.
A gap theorem for Ricci-flat 4-manifolds

Field: Mathematics (Physical Sciences)

Let $(M,g)$ be a compact Ricci-flat 4-manifold. For $p \in M$ let $K_{max}(p)$ (respectively $K_{min}(p)$) denote the maximum (respectively the minimum) of sectional curvatures at $p$. We prove that if $$K_{max} (p) \le \ -c K_{min}(p)$$ for all $p \in M$, for some constant $c$ with $0 \leq c < \frac{2+\sqrt 6}{4}$, then $(M,g)$ is flat. We prove a similar result for compact Ricci-flat Kähler surfaces. Let $(M,g)$ be such a surface and for $p \in M$ let $H_{max}(p)$ (respectively $H_{min}(p)$) denote the maximum (respectively the minimum) of holomorphic sectional curvatures at $p$. If $$H_{max} (p) \le -c H_{min}(p)$$ for all $p \in M$, for some constant $c$ with $0 \leq c < \frac {1+\sqrt 3}{2}$, then $(M,g)$ is flat.
Expression of PGP9.5 and NCAM in soft palate of obstructive sleep apnea hypopnea syndrome patients

Field: Medicine (Health Sciences)

Objective To study the protein gene product 9.5(PGP 9.5) and NCAM(neural cell adhesion molecule) expression and the peripheral nerve distribution in soft palate of obstructive sleep apnea hypopnea syndrom(OSAHS) patients.Methods 30 patients with OSAHS were selceted as the experimental group while 10 patients diagnosed as the simple chronic tonsillitis excluded OSAHS as control group.Nerve distribution in the tissue of the soft palate was evaluated by HE staining detection.The expressions of PGP9.5 and NCAM were detected in both groups by immunohistochemistry method.Results ① The distributions of different levels in soft palate nerve were different.The distribution of peripheral nerve mainly distributed in the submucosa,glands,blood vessels,and there was a small amount of distribution around the muscle tissue;② The expression of PGP9.5 and NCAM in OSAHS patients were significantly higher than the control group,which had statistical difference(P 0.05);③ In OSAHS patients,the expressions of NCAM and PGP9.5 apnea were positively correlated to apnea hypopnea index,the correction indexs were 0.706 and 0.636 respectively(P = 0.01).Conclusion The results indicate that nerve abnormalities occur in the soft palate of OSAHS patients.The more heavier of OSAHS,the more abnormalities in the soft palate.
A study of collimation and extraction of the U-70 accelerator beam using an axially oriented crystal

Field: Physics and Astronomy (Physical Sciences)

Extraction and collimation of the 50-GeV proton beam with a bent silicon crystal at the U-70 accelerator of the Institute for High Energy Physics (Protvino, Russia) was investigated. Until recently, proton beam extraction (and collimation) from accelerators has been effected using crystals with the (111) or (110) plane orientation, when the beam propagates far from the crystal axes. In the described experiment, the silicon crystal was oriented so that the proton beam was incident on it near the 〈110〉 axis. Under these conditions, a part of the beam was deflected by the crystal owing to the dynamic chaos phenomenon. The maximum beam extraction efficiency was as high as ~80%.
The Effects of Aroma Hand Massage on Anxiety and Sleep in Cancer Patients during Hospitalization

Field: Nursing (Health Sciences)

Purpose: This study was conducted to investigate the effects of aroma hand massage on anxiety and sleep in cancer patients during hospitalization. Methods: This study used a pre-post non-synchronized quasi-experimental design. Data were collected from 66 participating patients from July to December 2008. The participants were divided into an aroma massage group (n=25), a hand massage group (n=15), and a control group (n=26). The experimental group received aroma hand massage using 1% diluted lavender aroma oil once per day for 3 days. The massage was given by the researcher following the Korea Aromatherapy Health Professional Association massage protocol In contrast control group A received only a hand massage. The state anxiety, sleep condition, sleep satisfaction levels, and sleep duration were measured before and after the intervention trial. Results: The aroma hand massage group experienced in a significant decrease in their state anxiety (F=7.658 p = .001). Moreover, there was a significant increase in their sleep condition (F=18.047, p = .001), sleep satisfaction (F=30.016, p= .001) and sleep duration (F=23.019, p= .001) compared to the other groups according to one-way ANOVA and Scheffe's multiple comparison test. Also, noted was a significant increase in the sleep condition of the hand massage group as in the aroma hand massage group according to the Scheffe test. Conclusion: The study findings indicates that aroma hand massage decreases anxiety and increases the sleep condition, sleep satisfaction, and sleep duration of cancer patients.
Discovery of a Novel Regulatory Mechanism of TNK1 by 14-3-3 and Its Ubiquitin Association Domain Provides a Potential Therapeutic Targeting Opportunity in Cancer

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

While a relatively limited number of known oncogenes underlie a large percentage of cancers, a variety of new genes have emerged as low-frequency cancer drivers. Each of these new oncogenes represents a frontier for targeted therapy. However, the discovery of low-frequency targetable oncogenic drivers is challenging. This study focuses on the poorly understood Tyrosine kinase non-receptor-1 (TNK1), which has been reported to have both oncogenic and tumor suppressive functions. TNK1 has been identified to promote cancer cells survival and promote chemoresistance in multiple independent studies. On the other hand, whole-body constitutive deletion of TNK1 in mice caused an increase in spontaneous carcinomas and lymphomas. All in all, with no known regulatory mechanism and substrates of TNK1, the precise biological role of TNK1 is still unclear. To understand how TNK1 is regulated, we employed a proteomic approach to identify TNK1 interactors. We found out that TNK1 interacts with the phospho-binding protein 14-3-3 and this interaction is mediated by a cluster of MARK-mediated phosphorylations within the proline-rich domain. 14-3-3 binding retains TNK1 in the cytosol and maintains TNK1 in an inactive state. Release of TNK1 from 14-3-3 binding drives TNK1 to a heavy membrane fraction, where it becomes highly active. One unique feature of TNK1 is an ubiquitin association domain (UBA) on its C-terminus. Our data suggest that the UBA domain of TNK1 binds to poly-ubiquitin chains in nondiscriminatory manner. Remarkably, point mutations within the UBA that disrupt ubiquitin binding abolish TNK1 activation and oncogenic signaling, suggesting, to our knowledge, a unique UBA-centric mechanism of tyrosine kinase regulation. Finally, we used a structure-guided approach to identify a small molecule inhibiting TNK1 with high potency and selectivity. Such compound, TP-5801, inhibits TNK1 dependent STAT3 phosphorylation. TP-5801 also prolongs the survival of mice injected via tail vein with TNK1-driven Ba/F3 cells and reduces tumor burden in a subcutaneous xenograft model. In conclusion, our data reveal a mechanism of TNK1 regulation that controls its oncogenic tyrosine kinase activity and a potential strategy for TNK1 inhibition.
An enabling framework for civilian-military coordination and cooperation in peacebuilding and natural resource management: Challenges and incremental progress

Field: Social Sciences (Social Sciences)

This chapter traces the development of US civilian-military coordination in peacebuilding, particularly with respect to natural resources. It explains a brief history of US civilian-military coordination and cooperation; and a discussion of natural resources in the context of civilian-military coordination and cooperation. The committee was tasked with overseeing agency coordination and cooperation, resolving policy issues, and deciding on unified action. The defense, diplomacy, and development aspects of this approach form the basis for US civilian-military collaboration and US cooperation with the international community. The transition to civilian-military coordination and cooperation is neither smooth nor lateral. The process is characterized by periodic shifts—in particular, pullback from civilian agencies that are cautious about the militarization of foreign assistance, development, and diplomacy. Furthermore, the US Department of Defense (DOD) has transferred funds in support of civilian-led stabilization and reconstruction activities. Interagency fund transfers are a third means of promoting civilian-military coordination in the natural resource sector.
Isolation and Identification of Antifungal Polyketones from Bacillus velezensis DJ1 and Their Biocontrol Potential Against Corn Stalk Rot

Field: Agricultural and Biological Sciences (Life Sciences)

Corn stalk rot, caused by Fusarium graminearum, severely threatens corn production, while chemical fungicides lead to resistance and environmental risks. Thus, exploring environmentally friendly biocontrol agents is crucial. Though Bacillus polyketones have antifungal activity, their active components, corn stalk rot biocontrol potential and rhizosphere impacts remain unclear. This study isolated polyketones from Bacillus velezensis DJ1, assessed their antifungal activity and mechanism against F. graminearum, verified greenhouse efficacy, analyzed rhizosphere microbiota, and identified active components via HPLC-HDMS Q-TOF. The results showed that DJ1 polyketones showed dose-dependent inhibition by disrupting F. graminearum’s mycelium and membrane, with 44.33% greenhouse control efficacy. They did not disturb rhizosphere balance, only increasing Bacteroidota and DYGX01, and the active components were difficidin and bacillaene. These findings confirm DJ1 polyketones as promising eco-friendly biocontrol agents, providing a new strategy for sustainable corn stalk rot management.
Development of a multidisciplinary care pathway for people with profound and multiple learning disabilities

Field: Health Professions (Health Sciences)

The adult community learning disability team in Cornwall made a commitment to provide a better service for people with profound and multiple learning disabilities (PMLD). This resulted in audits against government papers and reports that encourage high-quality care for people with PMLD and a range of projects, including care pathway development and implementation, staff training and improving links with primary care. The care pathway aims to provide multidisciplinary assessment and intervention for people’s specialist health needs. Evidence shows that it has had a positive effect, but also identified areas for further work. Further recommendations have been proposed to improve care delivery for people with PMLD in the Cornwall adult learning disability service.
The Public Health Community Platform: Implementing Electronic Case Reporting

Field: Health Professions (Health Sciences)

The Public Health Community Platform (PHCP) is currently piloting an initial implementation of an electronic case reporting (eCR) solution. This work integrates community-defined resources (such as the Reportable Conditions Knowledge Management System and the Reportable Conditions Trigger Codes) to extract standardized data from clinical EHRs and transport that data to the correct public health agency, automating a core function of public health surveillance. This eCR solution will allow public health to benefit from a centrally developed and deployed infrastructure and tools and decrease the burden for clinical provider participation.
Noninvasive prenatal tests for chromosomal abnormality screening in in vitro fertilisation elderly pregnant women in northwest China

Field: Medicine (Health Sciences)

Background: The study aimed to explore the value of using noninvasive prenatal tests (NIPT) in the second trimester of pregnancy for chromosomal abnormality screening in vitro fertilisation (IVF) in elderly pregnant women and to analyse the reasons for inconsistent screening results in northwest China. Methods: A total of 47,286 pregnant women aged 19-51 who underwent prenatal examinations were collected. NIPT detection found that the positive rate of pregnant women aged &gt; 35 with spontaneous pregnancy was 0.78% , and the positive rate of IVF pregnancy was 0.82%. Then, the detection accuracy of NIPT for pregnant women aged &gt;35 with IVF was further analysed. Results: NIPT's sensitivity, specificity, and positive predictive value in detecting common chromosomal aneuploidies (T21, T18, and T13) in pregnant women aged &gt;35 who received IVF were 99.72% , 99.78% , and 66.45% , respectively. The mean gestational age, pregnancy number, AFP, and free b-HCG significantly differed between the positive and false positive groups (P &lt; 0.05). Logistic analysis showed that the mean gestational age and AFP were independent risk factors for the failure of NIPT diagnosis (P &lt; 0.05). Conclusions: NIPT has a particular detection performance for common chromosomal aneuploidies IVF in pregnant women. However, factors affecting detection accuracies must be considered when using it.