jimnoneill/paper-to-field-training huggingface dataset:
MOLECULAR MECHANISMS OF ACTION OF MAGNESIUM OROTATE ON CARDIOVASCULAR SYSTEM

Field: Medicine (Health Sciences)

Orotic acid is one of the intermediates in the pyrimidine biosynthesis. Mechanisms of physiological effects of orotic acid are poorly known. Analysis of data about these mechanisms is presented. Effects of orotic acid and magnesium orotate on cardiovascular system as well as therapeutic implementation of magnesium orotate in cardiology are discussed.
The ‘Ginsburg Rule’ Is Not an Excuse to Avoid Answering the Senate’s Questions

Field: Social Sciences (Social Sciences)

An op-ed by Lori Ringhand and Paul M. Collins Jr. on Supreme Court nominees' unwillingness to provide answers on cases under the wrongly named "Ginsburg Rule." Nominees since the 1930s have balanced the competing needs of the Senate and the Judiciary by claiming a privilege to not opine on currently contested cases while freely offering their opinion about cases that used to be controversial but are no longer.
Developing Impact Investment Opportunities for Return-Seeking Capital in Sustainable Marine Capture Fisheries

Field: Economics, Econometrics and Finance (Social Sciences)

different timelines in which they expect to realize financial gains. Impact investment:An investment that actively achieves positive (and measurable) social or environmental results while generating financial returns.To achieve these other objectives, impact investors are sometimes willing to wait longer for financial returns (patient capital), accept a lower return than commercial rates, or accept more risk.Impact capital usually flows to projects in several ways:• Equity financing: A company sells stock or shares to investors.• Fixed income/debt financing: Companies or governments borrow money from investors or financial institutions with an obligation to pay back the principal plus interest (also referred to as debt financing; this includes the sale of bonds).
PRETREATMENT LYMPHOCYTE COUNT AS PROGNOSTIC FACTOR IN PATIENTS WITH HEAD-AND-NECK CANCER

Field: Medicine (Health Sciences)

目的：本文主要探討治療前淋巴的數量是否會影響接受根治性放射治療的頭頸癌患者預後。材料與方法：本研究回溯收錄610位於林口長庚醫院接受過根治性放療之頭頸癌病患。整體追蹤的中位時間長度為5.13年。根據療程前淋巴球數量的多寡（＜ 1,885 cells/μL vs. ≥ 1,885 cells/μL）分群後，進行存活率、局部控制率、區域控制率及遠端轉移存活率的分析。結果：治療前的淋巴球數量的中位數為 1,885 cells/μL（範圍：285-5341）。相對於治療前有較少淋巴球的群體，較多淋巴球的族群有顯著較高的身體質量指數（BMI）、較高比率吸煙及喝酒者。在經過多變量分析後，治療前有較多淋巴球的群體比起較少的一方，在整體存活率及無遠端轉移存活率上有統計學上顯著較佳的表現。在局部及區域腫瘤控制率上，則無觀察到差異。結論：本研究觀察到在接受根治性放療的頭頸癌患者，治療前有較多淋巴球能有較佳的整體存活率及無遠端轉移存活率
Occurrence Download

Field: Agricultural and Biological Sciences (Life Sciences)

A dataset containing 3079194 species occurrences available in GBIF matching the query: { "and" : [ "TaxonKey is one of (Persicaria maculosa Gray, Melampyrum pratense L., Nardus stricta L., Festuca ovina L., Potentilla anglica Laich., Euphorbia esula L., Epipactis purpurata Sm., Viola odorata L., Fragaria moschata Duchesne, Chaerophyllum aromaticum L., Oxalis stricta L., Acer campestre L., Rhamnus cathartica L., Lathyrus niger (L.) Bernh., Campanula rapunculoides L., Melittis melissophyllum L., Erigeron annuus (L.) Pers., Danthonia decumbens (L.) DC., Ajuga genevensis L., Carex caryophyllea Latourr., Parthenocissus vitacea (Knerr) Hitchc., Ctenitis excelsa (Desv.) Proctor, Pinus strobus L., Brachypodium pinnatum (L.) P.Beauv., Polygonatum odoratum (Mill.) Druce)", "HasCoordinate is true", "HasGeospatialIssue is false", "OccurrenceStatus is Present", "Geometry POLYGON((-11 34, 41 34, 41 72, -11 72, -11 34))", { "not" : { "BasisOfRecord" : [ "is one of (Fossil, Living Specimen)" ] } } ] } The dataset includes 3079194 records from 3255 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000152-230918134249559/datasets/export for details. Data from some individual datasets included in this download may be licensed under less restrictive terms.
Evaluasi Kesiapan Modernisasi Sistem Irigasi di Daerah Irigasi Krueng Jreu Kabupaten Aceh Besar

Field: Environmental Science (Physical Sciences)

Irrigation modernization as a fundamental transformation of irrigation water resources management which aims to increase the utilization of human resources and services provided to a farmer in an effective, efficient, and sustainable manner based on the five pillars of irrigation modernization. This study aims to evaluate the readiness of modernization Krueng Jreu Irrigation Area based on the 5 pillars of irrigation modernization. The research method was observation, interview, and research documentation. The results showed that the index value of modernization readiness in Krueng Jreu on the pillars of water availability with a value of 10, the pillars of irrigation infrastructure with a value of 19.8. Pillars of the irrigation management system with a value of 14, the pillars of irrigation management institutions with a value of 9 and the pillars of human resources for irrigation management with a value of 6. The total value of the index for modernization readiness in Krueng Jreu is 58.8 which is categorized as sufficient, irrigation modernization is postponed and must make improvements within 1-2 years.
Predictive Value of Neutrophil To Lymphocyte Ratio and Sequential Organ Failure Assessment Score in Patient With Sepsis

Field: Medicine (Health Sciences)

Background: Neutrophil to lymphocyte ratio calculated from white cell differential count provides a rapid indication of the extent of an inflammatory process. The aim of the study was to evaluate the predictive value of neutrophil to lymphocyte ratio and SOFA score in sepsis outcome. Methods: Adult patients presenting to medicine department of CMCH with suspected sepsis by qSOFA score were considered for the present study. Baseline qSOFA, SOFA Score and NLR were calculated. Patients were followed until discharge or death to observe outcome. The primary outcome was in-hospital mortality. Secondary outcomes were ICU referral and ICU stay. All data were prospectively collected, coded and tabulated. ROC curves were constructed to evaluate the performance of NLR and SOFA in differentiating non-survivors from survivors. Multivariate logistic regression analysis was done to determine the independent predictors adjusted for the previously specified baseline covariates. Results: The AUC for each indicator was compared. NLR had a modest power for predicting unfavorable outcome (death) as suggested by AUC of 0.705 (95% CI: .556-.854), which was greater than that of baseline qSOFA score (0.694). NLR ≥ 8.9 was proposed as the optimal cutoff value, which provided a sensitivity of 75.0% and a specificity of 67.7% for predicting mortality in sepsis. After adjusting for other variables NLR and SOFA remain as independent predictors of unfavorable outcome. Baseline NLR also had a modest power for predicting need for ICU referral than that of baseline SOFA score. Conclusion: NLR is an easily calculated, simple, cost-effective index that could be used as a prognostic tool for clinicians when assessing sepsis patients in the emergency department and general ward. Bangladesh J Medicine 2023; 34(2): 86-92
Transcriptomic analysis of Andrias davidianus meat and experimental validation for exploring its bioactive components as functional foods

Field: Agricultural and Biological Sciences (Life Sciences)

Andrias davidianus (Chinese giant salamander, CGS) is the largest and oldest extant amphibian species in the world and is a source of prospective functional food in China. However, the progress of functional peptides mining was slow due to lack of reference genome and protein sequence data. In this study, we illustrated full-length transcriptome sequencing to interpret the proteome of CGS meat and obtain 10703 coding DNA sequences. By functional annotation and amino acid composition analysis, we have discovered various genes related to signal transduction, and 16 genes related to longevity. We have also found vast variety of functional peptides through protein coding sequence (CDS) analysis by comparing the data obtained with the functional peptide database. Val-Pro-Ile predicted by the CDS analysis was released from the CGS meat through enzymatic hydrolysis, suggesting that our approach is reliable. This study suggested that transcriptomic analysis can be used as a reference to guide polypeptide mining in CGS meat, thereby providing a powerful mining strategy for the bioresources with unknown genomic and proteomic sequences.
Dietary Lipids in Tuberculosis

Field: Medicine (Health Sciences)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Recent Advances in the Treatment of Delusional Disorder

Field: Medicine (Health Sciences)

Objective: Often considered difficult to treat in the past, even treatment-resistant, delusional disorder is now regarded as a treatable condition that responds to medication in many instances. Munro and Mok previously reviewed the published record of its treatment to 1994. This review aims to update and extend their observations and to examine the impact of new second-generation antipsychotic agents on the treatment of this condition. Method: We attempted to gather all published reports of delusional disorder from 1994 to 2004, using various database strategies. We then assessed the reports for clarity and completeness, treatment, and outcome descriptions, thereby selecting a patient sample for analysis. Results: Of 224 cases identified as delusional disorder, only 134 case descriptions provided sufficient treatment and outcome data to inform this review. The demographics of this sample were similar to those of the earlier review. Depression as a comorbid condition was more frequent than before. Adherence to medication regimens was seldom explicitly addressed. Most cases showed improvement regardless of which antipsychotic medication the patients received. Pimozide and other conventional antipsychotics, as well as second-generation antipsychotics, and even clozapine, were used in many of the case reports. Family history of delusional disorder was seldom recorded. Conclusions: A positive response to medication treatment occurred in nearly 50% of the cases in our review, which is consistent with the earlier review.
Budgetary Control, Managerial Competencies and Performance of Higher Local Governments in Eastern Uganda

Field: Business, Management and Accounting (Social Sciences)

The study aimed to explore the correlation between budgetary control, managerial competencies, and the performance of higher local governments in Uganda's Eastern region. Through a cross-sectional research design, 30 higher local governments out of a population of 32 were analyzed against predictor variables. Validity and reliability tests were conducted on research instruments to ensure data quality. Findings revealed a positive and significant relationship between budgetary control and performance, as well as between managerial competencies and performance. Moreover, there was a statistically significant relationship between both budgetary control and managerial competencies on performance. Regression analysis showed that 55.9% of performance variation was explained by these factors, leaving 44.1% to other factors not considered. Recommendations include strengthening financial management processes and investing in training programs to enhance managerial skills, ultimately improving local government performance.
Analysis of Motor Cooling Lines of Electric Buses with 1D Models and Verification with Experiments

Field: Engineering (Physical Sciences)

<div class="section abstract"><div class="htmlview paragraph">Improving the overall thermal management strategy in electric vehicles can directly or indirectly improve battery efficiency and vehicle range. The aim of this study is to simulate and improve the performance of motor cooling lines developed for an electric bus using 1D computational fluid dynamics models. In the study, simulation studies were carried out for the 12-m EV Citivolt vehicle of Anadolu Isuzu. Design parameters such as placement of flow lines and component selection were decided thanks to 1D models developed. The design obtained at the end of the study was supported by tests and experimental studies. As a result, it was seen that the components in the line correctly detected the flow rate and pressure losses with a maximum error rate of 8% and an average error rate of 4.8%. Additionally, the components on the line were added to the model via their own characteristic dp-Q curves. In this way, it has been seen that these components, which contain complex flow lines, can be represented with unique dp-Q curves.</div></div>
The GNAS SNP c.393C>T (RS7121) as a Marker for Disease Progression and Survival in Cancer

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

G-protein receptor signaling plays a key role in multiple signal transduction pathways. Aberrant activity of the stimulatory Gsα subunit has been frequently associated with cancer. GNAS sequence alterations and conformational changes of Gsα can both enhance or diminish its function and change downstream effects of G-protein receptor signaling. In this review and meta-analysis, we focus on the synonymous SNP rs7121 (FokI, c.393C>T), which is associated with either tumor progression or prolonged survival in cancer patients (overall hazard ratio = 2.256; p < 0.001). We finally point out the relevance of GNAS rs7121 as a promising biomarker and a prediction tool for therapy response and the need of further experiments to implement it into routine clinical diagnostics.
Students Diagnosed with Attention Deficit Hyperactivity Disorder: Collaborative Strategies for School Counselors

Field: Psychology (Social Sciences)

The school setting can be a difficult place for children with attention deficit hyperactivity disorder (ADHD). The core symptoms of ADHD, which include inattention, hyperactivity, and impulsivity, make meeting the curriculum demands of the classroom challenging. That ADHD negatively impacts not only academic performance but also social and emotional functioning is well established (Lee, Lahey, Owens, & Hinshaw, 2008). Given the negative consequences of ADHD, effective school-based interventions are warranted. School counselors are uniquely positioned to implement strategies for children with ADHD to maximize their capacity for learning. This article provides specific strategies that school counselors can provide collaboratively to enhance the academic and social functioning of children with ADHD in school.
Mobility management in IEEE 802.11 WLAN using SDN/NFV technologies

Field: Computer Science (Physical Sciences)

Abstract IEEE 802.11 wireless LAN is proliferating since the increased trend in the wireless network utilization on mobile devices. Accuracy, fast content delivery, and reliable mobility support are essential features of any network to support the changing trend in a wireless network. However, traditional architectures in wireless LAN (WLANs or WiFi) always endured from challenges such as the provision of consistent mobility, real-time packet flow, and seamless handoff. Generally, most of the WLAN only relies on signal strength for handoff which is not sufficient enough for fair selection of an access point (AP) and therefore causes imperfect performance of the network. We present a novel mobility management scheme for WLANs to deal with the mobility management issues, and load balancing by software-defined network (SDN) and network function virtualization (NFV) technologies. The proposed scheme is based on logical AP (LAP) that keeps a connection with the user/mobile terminal (MT) during handoff triggered by either the user or the SDN controller for seamless mobility. It also involves the current state of each AP in addition to traditional parameters of WLAN. We implemented the proposed scheme on a real testbed in a WLAN environment. The evaluation results authenticate that our proposed scheme provides robust handover without throughput degradation and load imbalance among adjacent APs, and allocates the best AP in the neighboring region. Moreover, our proposed scheme is feasible to implement since it did not require any modification at the mobile terminal.
THE "THEORY OF INSTRUCTIONAL DIALOGUE"

Field: Social Sciences (Social Sciences)

This chapter presents a unified theory of instructional design in the cognitive domain; this includes, of course, online instructional modeling. The theory differs from specific instructional design theories in that it describes how all instructional systems operate (regardless of their goals) in terms of resources and dialogues common to all instructional systems; it predicts certain instructional outcomes (related to groups of learners, not to individual learners) based on given initial conditions. The theory affords practical and theoretical advantages. Practically, it (1) simply and accurately describes the mechanisms at play in instructional systems, (2) presents readily quantifiable operational definitions, (3) suggests hypotheses that may be evaluated empirically and (4) points the way toward optimizing instructional systems. Theoretically, it (1) subsumes all current theories of instructional design and (2) views campus-based, distance and online instructional systems as a single discipline.
Polar Activity Watch 200: a new device to accurately assess energy expenditure

Field: Health Professions (Health Sciences)

Objectives Energy expenditure (EE) based on movement detection is calculated by a new device, the Activity Watch 200 (AW200). The aim of this study was to validate EE measured by this device against indirect calorimetry (IC) and to assess the reproducibility of AW200 measurements. Design EE was assessed during a 9.7 km hike. 10 men and 10 women in the age range 35–45 years, and 5 men and 6 women in the age range 50–55 years were tested. One in five participants of each age- and sex-matched group was equipped with a portable metabograph (Oxycon Mobil) for IC measurements. Data were collected every 30 min during the hike, and IC was extrapolated for the remaining four other participants of the group. Results During the total hike, there was a high correlation between EE obtained from the AW200 and the IC calculation (r = 0.987, p<0.001). Identical values of EE were calculated by both methods during the first 90 min of the hike. However, EE calculated by the AW200 at 120 min and at the end of the hike was lower (p<0.05). Bland–Altman analysis showed limits of agreements between 105 and 279 kJ after 30 and 120 min, respectively. EE measured by the AW200 was well correlated with IC measurements, and limits of agreement between devices were below 10% of the measured values for hike durations longer than 60 min. Conclusion The AW200 appears to be a very useful and accurate device for measuring EE during exercise in recreational hikers and provides a useful tool for keeping track of personal EE.
Electromagnetic properties of sup 181 Ir: Evidence of. beta. -stretching

Field: Physics and Astronomy (Physical Sciences)

We have calculated the B(Ml)/B(E2) ratios in {sup 18l}Ir within a shape-fixed particle + rotor model, in order to investigate how sensitive these may be to the nuclear shapes under consideration, and whether or not there is evidence of shape coexistence in the electromagnetic data alone. The model calculations employed the same Woods-Saxon potential that has been used previously for TRS and bandhead calculations and all parameters have been taken at their standard values, without any adjustments. To the extent possible with present models, these calculations should represent predictions for the B(M1)/B(E2) ratios at the deformations expected from the TRS and bandhead calculations. A comparison with the {sup 181}Ir data is stimulated by the fact that this is the lightest-mass Ir nucleus for which the spins and parities am firmly established experimentally; we find that the electromagnetic transition rates in this nucleus are well reproduced under the assumption of a single, fixed shape.
Bladder cancer collaborative stage variables and their data quality, usage, and clinical implications: A review of SEER data, 2004‐2010

Field: Medicine (Health Sciences)

BACKGROUND Several changes were made to bladder cancer staging guidelines between the 6th and 7th editions of the American Joint Committee on Cancer (AJCC) Staging Manual . Also, Collaborative Stage (CS) Data Collection System version 2 (CSv2) implemented for 2010 Surveillance, Epidemiology, and End Results (SEER) cases involved collection of 3 new site‐specific factors (SSFs): World Health Organization/International Society of Urological pathology grade (SSF1), size of metastasis in regional lymph nodes (SSF2), and extranodal extension (SSF3). Our objective was to evaluate these new SSFs to assist researchers in their use/interpretation and to describe data quality issues to be addressed moving forward. METHODS Staging trends were assessed for invasive and noninvasive bladder cancer cases from 2004 to 2010. Among 2010 cases, staging was compared using the AJCC 6th and 7th edition guidelines, and evaluation of completeness/quality of the SSFs was performed in relevant subgroups. RESULTS Age‐adjusted incidence rates and proportions of cases by stage remained steady from 2004 to 2010. Changes from the AJCC 6th to 7th editions caused no substantial movement between stages. SSF1 had a known value in 82% of cases, which was higher than the traditional SEER grade/differentiation variable. SSF2 and SSF3 were less complete, with 41% and 37% having known values, respectively, among cases with lymph node involvement (according to CS lymph node variable). CONCLUSIONS SSF1 was more complete and straightforward to interpret than the traditional grade/differentiation variable. SSF2 and SSF3 were less complete, may be associated with data quality issues, and should only be used among cases with known lymph node involvement Cancer 2014;120(23 suppl):3815‐25. © 2014 American Cancer Society .
Review and Evaluation of Methods for Assessing Ungulate Nutritional Condition

Field: Agricultural and Biological Sciences (Life Sciences)

Nutritional condition is a key factor influencing the reproductive success and survival of ungulates. It is also an important part of the information required to make management decisions for wild ungulate populations. Most of the methods used in assessing the nutritional condition of ungulates are briefly reviewed. The advantages, disadvantages, prerequisites, theoretical models and applicability of each method is discussed. Ways to avoid common errors and improve the accurateness and precision of each method are evaluated.