jimnoneill/paper-to-field-training huggingface dataset:
Dissecting the Molecular Determinants that Mediate Protein/RNA Interactions at the Synapse

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The NOVA family of RNA‐binding proteins consists of neuron‐specific splicing regulators that are targeted in an autoimmune neurodegenerative motor disorder. They are sequence‐specific splicing factors, with a modular structure consisting of three KH domains that mediate protein‐RNA interactions. One of the targets of NOVA is a neuron‐specific isoform of the ubiquitously expressed gene AGRIN. This splice variant, termed Z + AGRIN, is secreted by neurons and is found at the synaptic cleft at the neuromuscular junction (NMJ), a synapse between a nerve cell and a muscle cell, and the best‐studied model synapse. By inducing the clustering of acetylcholine receptors (AChR) on the postsynaptic membrane, Z + AGRIN promotes the formation, maintenance, and development of the NMJ. The Z exons are also of particular interest as they are potential mutation sites in congenital neuromuscular diseases. The study of NOVA function in vertebrates is complicated by the presence of two NOVA genes termed NOVA1 and NOVA2. The tunicate Ciona robusta is a marine invertebrate that is the closest living relative to vertebrates. Interestingly, Ciona has only one Nova gene. We used the NOVA‐AGRIN paradigm to study the evolution of nerve cell specific protein‐RNA interactions. We cloned and characterized Nova proteins from Ciona and generated Agrin minigenes that recapitulate the action of Nova in a tissue culture cell system. Here, we identify the specific Agrin pre‐mRNA nucleotide sequences that mediate Nova‐dependent splicing of Z + agrin in tunicates. Support or Funding Information National Institutes of Health This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .
The Influence of Leukocyte and Platelet Concentrate Enrich in Stem Cells on Bone Regeneration Processes: A Clinical and Flow Cytometry Study

Field: Medicine (Health Sciences)

This article reports the efficacy of percutaneous autologous leukocyte- and platelet-rich plasma (L-PRP) injection into delayed union site as a minimally invasive method alternative to bone marrow aspirate and open grafting techniques. Each of 15 participants was followed on a regular basis with clinical examinations, roentgenograms. The average time to union was 8.4 weeks after L-PRP injection and the union was achieved in all cases. CD34+/45+ cells counts were increased by 410% and CD34+/45- cells counts were increased by 488% on average in L-PRP. Our investigation showed that L-PRP enrich in stem cells can produce the desired stimulatory response despite a substantial amount of vital bone cells from mesenchymal line. We believe that the using of L-PRP enriched in stem cells, growth factors and antimicrobial proteins might be a promising treatment method in regenerative medicine.
Towards a Possible Entropy-Driven Process of Consciousness

Field: Neuroscience (Life Sciences)

In the present article, we argue that consciousness and body are not to be separate to explain the intentional consciousness of the human being facing to environment. 1) The most neurobiologist and neurocognitivist studies suggest that the emerging consciousness appears to be a generic recurring process which subsumes under it the various results of scientist approaches. When analyzed with the cybernetic transductive method of Simondon, this process can be viewed as a noetico-neuronal unit which the sui generis activity can be boiled down to concept of intentional consciousness. 2) Homeostasis can be also metaphorically described as a generic recurring process which subsumes under it the myriad molecular feedback loops of organism. This self-regulating dynamic process could be governed by the cosmologic (Earth + Universe) production of entropy, which would keep high activity and dissipating energy and low internal entropy to maintain an ordering in the organic structure. 3) Based on numerous arguments and data, the cerebral noetico-neuronal process and the self-regulating homeostasic process may be viewed as an entire physiological (brain + body) system. We suggest that the whole (brain + body) has an intentional embodied consciousness that could be driven by the cosmologic production of entropy.
Hard Templates for Soft Materials: Creating Nanostructured Organic Materials

Field: Materials Science (Physical Sciences)

This review describes the possibilities of using hard templates to create nanostructured "soft" materials, for example, polymer networks, carbon nitrides, or carbonaceous materials, that is, materials which are still organic in their nature. Examples are given for the whole range of hard templates described in the literature, starting from silica nanoparticles, zeolites, and periodic mesoporous silicas to aluminum oxide membranes and colloidal crystals.
Savage Marks

Field: Arts and Humanities (Social Sciences)

This chapter analyzes how poststructuralist theory forgot, then rediscovered its roots in anthropology by investigating the conceptual genealogy of theories of subjection that imagine the production of the socialized subject as acts of inscription. It traces the obsession of poststructuralist theories with Kafka’s 1914 story “In the Penal Colony” and recontextualizes Kafka’s text in discourses on tattooing and body ornamentation in the late nineteenth and early twentieth centuries. The link between subjection and bodily inscription was first rooted in anthropological interest in tattooing, in the context of other, “primitive,” cultures then in the service of criminal anthropology, but, via Nietzsche and Foucault, became a universal theoretical imaginary. In a complementary move, theorists such as Derrida, Deleuze and Guattari, and Lingis allowed themselves to be haunted by the specter of anthropology and rediscovered inscription as another technology of writing, exemplified by the practices of other cultures, often in the service of countering “western” theories of subjection.
A comprehensive review of Guduchi ( Tinospora cordifolia (Wild.) Miers), the ambrosia of Ayurveda : A classical memoir

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

In Ayurveda, Guduchi, [Tinospora cordifolia (Wild.) Miers] is considered as a lead drug (agrya dravya) having multitude of therapeutic indications. This review provides a concise information regarding Guduchi, pertaining to its identifying characters, therapeutic properties and actions, being collected from 30 Nighantu (lexicons), 12 Samhita (treaties) and Chikitsa grantha (Compendia) and 15 Rasa grantha (Pharamcopoeia). The study reveals that, Guduchi is also known by about 79 other names (paryaya) , signifying its morphological features and pharmacological properties and actions. Guduchi possesses tikta, kashaya, katu rasa, laghu guna, ushna veerya, madhura vipaka and tridoshaghna property. Kandaguduchi, a variety of Guduchi, has also been pronounced and attributed with 12 synonyms, possesses katu rasa, ushna veerya and sannipatahara properties and highlighted for its categorical actions like Jvaraghni, Vishabhutghni and Valipalitnashini. Guduchi, singularly has been attributed with fourteen karma(action) and indicated in twenty one clinical conditions. It is one among the few herbs advocated to be used in ardra (fresh) condition.. Guduchi is also used in
pharmaceutical procedures like Shodhana (processing), Marana (calcination) and Jarana (incineration) of various metals and minerals. This review is expected to enrich the documentary evidences about classical references on Guduchi as add on to future researches.
[Hospital-acquired pneumonia caused by biological pathogens].

Field: Medicine (Health Sciences)

Hospital-acquired pneumonia (HAP) is recognized when the clinical and radiological symptoms appear in the 48-72 hours from the admission to the hospital or in the case of pneumonia during the mechanical respiration after 72 hours of the patient's intubation. The frequency of HAP placed between 5 to 15 per 1000 patients undergoing hospital treatment. The appearance of clinical symptoms: high fever, cough with expelling of purulent sputum, an increased number of breaths or dyspnoe and the occurrence of inflammation's morphological markers and the presence of new changes in the radiography (or severity seen earlier) confirms the diagnosis. Difficulties arise during the treatment of pneumonia caused by several strains of bacteria or flora which are resistant to available antibiotics. This is the reasons of high mortality among patients with HAP, reaching above 35%.
A Study on the Poetic Patterns in Laila Al-Atrash's Novel a Woman unlike Herself

Field: Arts and Humanities (Social Sciences)

The present article addresses the poetics of narrative in A Woman Unlike Herself by Laila Al-Atrash.The two elements the article explores are the poetics of the title and the poetics of the language, which the writer used to support the narrative point of view in the novel.The different patterns of poetics used in the novel, the article finds, contribute to improving the poetic narration.As an experienced novelist and journalist, Al-Atrash placed her work within poetic contexts that manifest her creativity and prowess in the use of language and expression of the narrative point of view.The article also finds that the novel features the rebellion of the protagonist, Habibat Al-Eyn, against fear, illness, death and love.The novel touches upon the problematics of immigration using a concise intensive language that primarily relies on displacement, irony, hermeneutics and imageries.The language the writer used effectively expresses a troubled emotional and psychological state of the protagonist who encounters intolerable conditions.At the end, the protagonist becomes a woman unlike herself.
THEORY AND PRACTICE OF FLOTATION DEINKING

Field: Chemical Engineering (Physical Sciences)

The performance of the preflotation stage of the Norske Skog Skogn DIP mill has been studied over the first year of operation. Process conditions have covered a wider range of process parameters than would normally be expected in an established mill. The main factor affecting free ink removal and filler yield was the process water hardness, and there was a negative correlation between free ink removal efficiency and filler yield. While filler loss was concluded to take place by flotation, physical entrainment seemed to be the main mechanism for fiber loss. An over-view of process variables important for mill-scale DIP flo-tation performance is given.
GEOLOGICAL CHARACTERISTICS OF TEHRAN AQUIFER

Field: Earth and Planetary Sciences (Physical Sciences)

The alluvial deposits of Tehran is composed of up to 1100 m and is divided into fiveparts: The first part (~500 m) has been denominated as first member of Hezardareh Formation andhas been formed of hard conglomerate of Upper Pliocene age. This part has many few porosity, higherodibility of pebbles and strongly cementation.The second part (second member of Hezardareh Formation has been composed of ~500 m ofincoherent conglomerate and conglomeratic sandstone deposits of Lower Pleistocene age. Thismember has highly porosity respect to first member and less grade of erodibility.The third horizon (Kahrizak Formation) with 10 to 60 m of thickness contains pebble, graveland sand. It is Middle Pleistocene in age.The fourth stage (Tehran alluvium) with 50 m of thickness has been formed by stratifiedgravels of Upper Pleistocene age. In general this Formation is composed of heterogeneous grainsand because of having frail cement between pebbles it is permeable and with relatively highmechanical resistance. Tehran alluvium has been the better depository of underground water in thealluvial fan of Tehran region.The fifth part (Holocene stage) with 1-5 m of thickness contains coating pebbles, gravel andfine sediments. It is composed of separated and highly permeable deposits, which its mechanicalresistance differs in different part of the region.The thickness of alluvial aquifer is estimated about 300-350 m, which composed of secondmember of Hezardareh and younger Formation.Much of the groundwater essential to agriculture and human existence emanetes from aquifersin Quaternary sediments of Tehran plain.According to our surveys and data, annually water consumption of Tehran city is about 700million meter cubic which 20.8% of it discharges from Quaternary deposited sediments.
Functional Test Generation Using Efficient Property Clustering and Learning Techniques

Field: Computer Science (Physical Sciences)

Functional verification is one of the major bottlenecks in system-on-chip design due to the combined effects of increasing complexity and lack of automated techniques for generating efficient tests. Several promising ideas using bounded model checking are proposed over the years to efficiently generate counterexamples (tests). The existing researchers have used incremental satisfiability to improve the counterexample generation, involving only one property by sharing knowledge across instances of the same property with incremental bounds. In this paper, we present a framework that can efficiently reduce the overall test generation time by exploiting the similarity among different properties. This paper makes two primary contributions: (1) it proposes novel methods to cluster similar properties; and (2) it develops efficient learning techniques that can significantly reduce the overall test generation time for the properties in a cluster by sharing knowledge across similar test generation instances. Our experimental results using both software and hardware benchmarks demonstrate that our approach can drastically reduce (on average three to five times) the overall test generation time compared to existing methods.
Spatiotemporal Variations in the Connectivity of Wetting and Nonwetting Phases during Water Alternating Gas Injection

Field: Engineering (Physical Sciences)

Water alternating gas (WAG) injection is a well-established technique that leverages the benefits of gas injection and waterflooding processes to improve the ultimate oil recovery. The connectivity of the fluid phases in a porous media is a crucial factor governing the mobility, displacement, and recovery of the multiple fluid phases during primary, secondary, or enhanced recovery operation. We develop, apply, and evaluate several statistical and computational functions capable of quantifying connectivity of a fluid phase of interest captured in the segmented microcomputed tomography scans of fluid-filled porous material undergoing WAG injection. These functions capture the evolution of three-dimensional connectivity of the wetting and nonwetting phases along the length of the sample during each injection process. The changes in connectivity of the fluid phases compared with the changes in fluid saturations better describe the effects of WAG injection and the recovery at each stage. This is a first-of-its-kind quantification of connectivity of wetting and nonwetting phases, focused on WAG injection. A robust quantification of the fluid phase connectivity in a porous material undergoing WAG injection facilitates a better understanding of the efficiency of the sequential injection strategies and reveals new approaches for improving oil recovery. The direct computation and comparison of the connectivity help determine the level of contribution of each injection cycle to the final recovery of the oil phase, thereby facilitating optimization of future injection strategies.
The Danish Fetal Medicine Database

Field: Medicine (Health Sciences)

Charlotte Kvist Ekelund,1 Tine Iskov Kopp,2 Ann Tabor,1 Olav Bjørn Petersen3 1Department of Obstetrics, Center of Fetal Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; 2Registry Support Centre (East) – Epidemiology and Biostatistics, Research Centre for Prevention and Health, Glostrup, Denmark; 3Fetal Medicine Unit, Aarhus University Hospital, Aarhus Nord, Denmark Aim: The aim of this study is to set up a database in order to monitor the detection rates and false-positive rates of first-trimester screening for chromosomal abnormalities and prenatal detection rates of fetal malformations in Denmark. Study population: Pregnant women with a first or second trimester ultrasound scan performed at all public hospitals in Denmark are registered in the database. Main variables/descriptive data: Data on maternal characteristics, ultrasonic, and biochemical variables are continuously sent from the fetal medicine units' Astraia databases to the central database via web service. Information about outcome of pregnancy (miscarriage, termination, live birth, or stillbirth) is received from the National Patient Register and National Birth Register and linked via the Danish unique personal registration number. Furthermore, results of all pre- and postnatal chromosome analyses are sent to the database. Conclusion: It has been possible to establish a fetal medicine database, which monitors first-trimester screening for chromosomal abnormalities and second-trimester screening for major fetal malformations with the input from already collected data. The database is valuable to assess the performance at a regional level and to compare Danish performance with international results at a national level. Keywords: prenatal screening, nuchal translucency, fetal malformations, chromosomal abnormalities
Classification of POLSAR images using a fast fuzzy C-medians clustering algorithm

Field: Computer Science (Physical Sciences)

The fuzzy c-medians clustering (FCMED) clustering algorithm is known to be a robust l/sub 1/ fuzzy clustering algorithm that works well even in the presence of outliers or remote small clusters. The well-known fuzzy c-means (FCM) clustering algorithm often performs poorly in this environment. Unfortunately, the FCMED has a high space-complexity, which makes its application impractical for large images. A new fast fuzzy c-medians clustering (FFCMED) algorithm is presented, which may be applied to any clustering problem, but is demonstrated here by classifying a POLSAR image. The FFCMED provides a robust clustering tool that works well for large images and data sets. A relative speed up over the FCMED of at least 3-to-1 was observed for the image illustrated in this paper.
Stereospecificity of the Photoinduced Conversion of Methylphenobarbital to Mephenytoin

Field: Chemistry (Physical Sciences)

Abstract Photochemically, an anion of S (+)‐5‐ethyl‐1‐methyl‐5‐phenylbarbituric acid is converted stereospecifically to R (‐)‐5‐ethyl‐3‐methyl‐5‐phenylhydantoin at room temperature. The R configuration is proposed for (‐)‐5‐allyl‐3‐methyl‐5‐phenylhydantoin.
A short overview of the History of Jews in the croatian part of Istria

Field: Arts and Humanities (Social Sciences)

U radu autorica daje kratki pregled povijesti Židova u Istri od njihove prve pojave u antici pa sve do suvremenog doba. Prateci povijesne dokumente koji govore o prisutnosti Židova u istarskim gradovima (Porec, Pula, Rovinj...) u srednjem i novom vijeku, pa cijelo 19. i 20. stoljece, autorica zakljucuje da istarske židovske zajednice nisu nikada dosegle organizaciju, brojnost i djelovanje kao sto su to židovske zajednice u ostalom dijelu Hrvatske, ali istarski su se Židovi ipak, osobito oni s kraja 19. i pocetkom 20. stoljeca uklopili u istarsko drustvo i postali dio istarske povijesti.
Pengaruh Investasi, Upah Minimum Kabupaten dan Kunjungan Wisatawan terhadap Penyerapan Tenaga Kerja di Provinsi Bali

Field: Economics, Econometrics and Finance (Social Sciences)

The contribution of the tourism sector in Bali Province has grown over the last twenty years, which can be seen from the number of tourist visits which has increased after the Covid-19 pandemic. The phenomenon that occurs is the gap between tourist visits which increases but the increase in investment and MSEs does not occur in all districts in Bali Province. This research aims to determine whether there is an influence of investment on labor absorption in Bali Province, to determine the effect of district minimum wages and tourist visits on labor absorption in Bali Province. This research was conducted in Bali Province in the 2019-2023 period. The sample in this study used tabular data techniques. The research method uses quantitative descriptive from the results of documentation studies related to investment data, district minimum wages and tourist visits. The results of this research are that there is a positive influence of investment on labor absorption in Bali Province, apart from that there is an influence of the district minimum wage and tourist visits on labor absorption in Bali Province. This research was conducted in Bali Province in the 2019-2023 period.
Methods of bronchial stump buttressing in post-pneumonectomy bronchopleural fistula prevention: a systematic review

Field: Medicine (Health Sciences)

<b>Introduction:</b> The bronchopleural fistula (BPF) remains one of the most severe complications after pneumonectomy. Several surgical methods may enhance bronchial stump healing and reduce the occurrence of BPF. Usually, surgeons use tissue buttressing, such as intercostal muscle flap (IMF), parietal pleura, pericardium fat pad, or mediastinal fat, to reinforce the bronchial stump. This paper reviews the literature describing the impact of different buttressing tissues on the occurrence of early post-pneumonectomy BPF.<b>Material and methods:</b> We included all studies that described the use of bronchial stump buttressing in patients after pneumonectomy. Studies written in languages other than English were excluded. The search was performed using PubMed, Google Scholar, Embase, COCHRANE databases, and the clinical trial registry on December 1, 2023. We used the following search input: "lung cancer" AND "pneumonectomy" AND ("bronchopleural fistula" OR "BPF") AND ("tissue buttressing" OR "intercostal muscle flap" OR "mediastinal fat pad"). We analysed the types of studies, the numbers of patients, and the most important conclusions. We performed descriptive statistics.<b>Results:</b> Twenty-seven articles on the use of bronchial tissue buttressing were identified. Nine papers were rejected due to small sample size (< 20 patients), surgical operation other than pneumonectomy or lobectomy, or papers older than 30 years. Ultimately, 16 articles were included in the analysis. Among them, three papers highlighted the statistically significant influence of bronchial stump buttressing in reducing the risk of BPF formation. Descriptive statistics were reported in nine studies, and two papers included the assessment of the blood perfusion in the buttressing tissue. Only one study was a randomized trial featuring a control group for comparison.<b>Discussion:</b> Buttressing the bronchial stump remains a controversial issue in thoracic surgery. It could be beneficial for high-risk patients. Among different tissues, the ideal one has still not been identified. Future research should incorporate control groups and intraoperative assessments of the blood supply to the tissue employed for bronchial buttressing.
Visualization of interfering RF-electric fields in a lossy liquid simulating a patient's body in a hyperthermia treatment by a LED-matrix

Field: Health Professions (Health Sciences)

Matrices Of LED-dipoles have been constructed as a cheap and easy-to-use tool for Quality Assurance in deep body hyperthermia. Placed inside a phantom, i.e. a watertank filled with saline, one type of LED-matrix visualizes axial E-field components, the other one both radial components of the E field. By moving of the matrix plate, the components of the E field can be monitored in the complete inner volume of the phantom. Due to the feature of measurements in real time, LED-matrices are especially suitable to check numerous variations of set-up parameters as e.g. phase and amplitude settings as well as the performance of deep body hyerthermia systems in clinical routine.