jimnoneill/paper-to-field-training huggingface dataset:
The true existence of man according to the teaching of St. Simeon the New Theologian

Field: Arts and Humanities (Social Sciences)

The article reveals the main aspects of the teaching of St. Simeon the New Theologian about deification from the perspective of the problems of authentic and inauthentic human existence. An analysis of this teaching is carried out in comparison with the thoughts of some representatives of modern philosophy and sociology. The concept of mysticism is also revealed, the teaching of modern philosophy about the authenticity and inauthenticity of human existence is assessed, and the concepts of existence and deification are differentiated. The article provides characteristics of the authentic and inauthentic existence of a person from the position of the Christian teaching of St. Simeon and from the point of view of some representatives of philosophy and sociology. It is concluded that existence and deification are not the same thing; it is said that inauthentic existence manifests itself in the form of imitation and oblivion, but genuine existence — in the vision of truth, “divine light”, God. The main sign of genuine existence is human repentance and questioning (prayer) (Heb. 5:7–9), and of inauthentic existence — pride and oblivion, which were the reasons for the fall of the first man Adam.
A framework for identifying functional modules in dynamic networks

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Detecting functional modules in Protein-Protein Interaction (PPI) networks is essential to understand gene function, biological pathways and cellular organisation. Majority of methods predict functional modules via the static PPI networks. However, cellular systems are highly dynamic and regulated by the biological networks. Considering the dynamic inherent within these networks, we build the time course PPI networks in terms of the gene expression profiles. And then a novel framework for identifying functional modules with core-attachment structure has been proposed in accordance with the dynamic PPI networks. Our algorithm generates the cores by mining co-expression neighbourhood graphs with an aggregation degree over a threshold and expands them to form functional modules. The method is compared with other competing algorithms based on two different yeast PPI networks. The results show that the proposed framework outperforms state-of-the-art methods.
Problematic Land Buying and Selling Transactions

Field: Social Sciences (Social Sciences)

Introduction: Land ownership has become a primary need, but in the process of land ownership there are still problems. Basically, the acquisition of land rights according to the Decree of the Minister of Agrarian Affairs Number 21 of Article 1 Point 1, the acquisition of land is carried out by transferring land rights or through the delivery of release of land rights followed by granting rights. But this activity is not carried out in its entirety so that it will cause problems in granting rights to the community. Purposes of the Research: This research was conducted in Sanahu Village, Elpaputih District, West Seram Regency. This village prioritizes and gives importance to matters relating to customary land. However, based on the dinamics of the community, transactions carried out by the community should be carried out in accordance with the provisions of the legislation governing land registration in order to obtain legal certainty in the transactions carried out and aim for orderly administration in land sector. Methods of the Research: This research method is empirical juridical research that uses primary and secondary data. The legal materials used are primary legal materials, secondary legal materials with questionnaire and interview methods, data collection techniques with literature studies and field studies. Data processing and analysis techniques use descriptive analytical data analysis by identifying, classifying, then analyzing and describing according to the hierarchy. Results of the Research: Based on have not carried out the first land the results of the interviews, it is known that some people in Sanahu village do not know about the sale and purchase practices that should be taken in order to obtain legal certainty from the sale and purchase transactions carried out. This should be done based on the provisions of Article 19 paragraph 2 of the UUPA, Article 37 of PP 24 of 1997 concerning land registration. As a result, in the event of problems related to previous land transactions, the community had to resolve themselves in a family manner, either without or with assistance from local officials. As a result, the people of Sanahu village have not carried out the initial registration and maintenance of land registration data properly. Because land administration is not orderly, if there are land issues in transactions carried out either by transferring rights or encumbering rights, there will be problems in the future and limit land owners in carriying out legal actions.
Distinctions between Overemployment, Overwork, Workaholism, and Heavy Investments in Work Time

Field: Economics, Econometrics and Finance (Social Sciences)

This chapter explores the role of incentives, explicit and implicit, in determining a worker's preferred number of hours. The former refers to extrinsic motivation, such as a monetary bonus for extra production. The chapter focuses on over employment, the inability to reduce one's work hours toward preferred shorter hours, despite a willingness to sacrifice some pay. It examines potential returns on investment in time not only in work time but in "non-work" time. The chapter aims to distinguish several separate types of non-work time uses, which are work-related and may have investment-type properties, such as "productive leisure." A comprehensive model of individuals' time devoted to work would incorporate the economic, psychological, physiological, social, and cultural sources of workers' constraints and preferences. The chapter concludes by exploring implications of the over employment findings and types of excessive work hours and non-work time uses for future research, both empirical and theoretical.
Effect of seawater on tensile and shear properties of composite material

Field: Materials Science (Physical Sciences)

This paper investigated the effect of moisture on the mechanical properties of glass fibre/bismaleimide composites. Specimens were immersed into simulated seawater baths at 30, 50 and 80˚C respectively and their weights were periodically recorded. The diffusion of the composite type was also obtained and compared. Tensile and shear tests were conducted on dry and soaked specimens in several configurations. Scanning electron microscopy was employed to study them. Results obtained showed that an increase in temperature accelerated the rate of moisture absorption. The creation of additional voids in the specimens was plausibly due to the effect of elevated temperatures. Fickian equilibrium was evident for specimens immersed in the 50 and 80˚C baths, while data from the 30˚C bath showed continual weight increments. A second stage diffusion behaviour was not observable. Data showed that the absorbed moisture degraded the tensile and shear properties of the specimens. The drop in shear properties was more significant than that of tensile properties. The slight drop in tensile performance plausibly resulted from the weakening of the matrix and interfacial bonding between fibres and matrix, while the moisture-resistant fibres continued to bear the load. As the 0˚ fibres were not utilised, the load was only distributed between the 90˚ fibres and the weakened matrix, hence resulting in a larger drop in shear properties. The disappearance of resin on the fibres, observed from SEM micrographs, was consistent with the tensile data. The slight degradation effect in mechanical properties recommended extended immersion duration to observe further changes in properties.
Development and Application of a quantitative Mass spectrometry based Platform for Thermodynamic Analysis of Protein interaction Networks

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

<p>The identification and quantification of protein-protein interactions in large scale is critical to understanding biological processes at a systems level. Current approaches for the analysis of protein -protein interactions are generally not quantitative and largely limited to certain types of interactions such as binary and strong binding interactions. They also have high false-positive and false-negative rates. Described here is the development of and application of mass spectrometry-based proteomics metehods to detect and quantify the strength of protein-protein and protein-ligand interactions in the context of their interaction networks. Characterization of protein-protein and protein-ligand interactions can directly benefit diseased state analyses and drug discovery efforts. </p><p>The methodologies and protocols developed and applied in this work are all related to the Stability of Unpurified Proteins from Rates of amide H/D Exchange (SUPREX) and Stability of Protein from Rates of Oxidation (SPROX) techniques, which have been previously established for the thermodynamic analysis of protein folding reactions and protein-ligand binding interactions. The work in this thesis is comprised of four parts. Part I involves the development of a Histidine Slow H/D exchange protocol to facility SURPEX-like measurements on the proteomic scale. The Histidine Slow H/D exchange protocol is developed in the context of selected model protein systems and used to investigate the thermodynamic properties of proteins in a yeast cell lysate. </p><p>In Part II an isobaric mass tagging strategy is used in combination with SPROX (i.e., a so-called iTRAQ-SPROX protocol) is used to characterize the altered protein interactions networks associated with lung cancer. This work involved differential thermodynamic analyses on the proteins in two different cell lines, including ADLC-5M2 and ADLC-5M2-C2. </p><p>Parts III and IV of this thesis describe the development and application of a SPROX protocol for proteome-wide thermodynamic analyses that involves the use of Stable Isotope Labeling by Amino acid in cell Culture (SILAC) quantitation. A solution-based SILAC-SPROX protocol is described in Part III and a SILAC-SPROX protocol involving the use of cyanogen bromide and a gel-based fractionation step is described in Part IV. The SILAC-SPROX-Cyanogen bromide (SILAC-SPROX-CnBr) protocol is demonstrated to significantly improve the peptide and protein coverage in proteome-wide SPROX experiments. Both the SILAC-SPROX and SILAC-SPROX-CnBr porotocols were used to characterize the ATP binding properties of yeast proteins. Ultimately, the two protocols enabled 526 yeast proteins to be assayed for binding to AMP-PNP, an ATP mimic. A total of 140 proteins, including 37 known ATP-binding proteins, were found to have ATP binding interactions.</p>
Bupivacaine Versus 2 Chloroprocaine Spinal Anesthesia Comparison Study at a Tertiary Hospital

Field: Medicine (Health Sciences)

Background: For surgery on the lower abdomen and lower limbs, spinal anesthesia is a tried-and-true, dependable, and safe anesthetic approach. It is simple to administer, acts quickly, poses little danger of infection, and has a low failure rate. Aims & objectives: The goal of the current study was to compare the effectiveness and readiness for discharge of the two local anesthetics used for spinal anesthesia, Bupivacaine and 2-Choroprocaine. Material and Methods: The current study was a short-duration (60min) elective ambulatory perineal surgery (such as a hemorrhoidectomy, a fistula in ano, a rectal biopsy, etc.) or gynecological procedure (such as a check curettage, hysteroscopy, etc.) prospective randomized double-blind study conducted in patients of 18 to 60 years of age, ASA grades 1 and 2, in 60 patients were randomly divided into two groups using a computer-assisted table: Group B received 40 mg of 1-chloroprocaine and Group C received 10 mg of bupivacaine hydrochloride as the spinal anesthetic. Results: In terms of mean age, gender, and ASA grade distribution, there was no discernible statistical difference between the two groups. A statistically significant difference was found between groups B and C for the mean time for onset of sensory block, mean time for onset of motor block, mean time to achieve maximum sensory block, mean duration of sensory block, and mean duration of sensory block. The chloroprocaine group showed better results in these areas. The mean length of stay in group C was 1.40 ±0.64 days and group B was 1.42 ± 0.82 days. There was significant difference in length of stay in two groups. (p<0.05) The mean time to ambulation in group C was 225.46 ±56.22 and group B was 265.36 ±58.46 minutes. The time it took for two groups to ambulate varied significantly. (p<0.05) This demonstrates that patients in Group C are discharged and ambulated earlier than those in Group B. Conclusion: In comparison to intrathecal Bupivacaine, intrathecal 2 percent 2-Chloroprocaine has the advantages of early ambulation and early hospital discharge. It also has an earlier and more satisfactory onset of sensory and motor block, the desired level of spinal block, and an adequate duration of sensory and motor block.
Heat and Mass Transfer within Unsteady Nanofluid Movement in the Presence of Sustained Solar Radiation

Field: Energy (Physical Sciences)

The unsteady movement of nanofluid on porous inclined media is essential for absorbing and transferring heat from solar radiation. From renewable energy sources, solar is limitless, sustainable and universally accessible without creating conflict. In this study, heat and mass transfer have been explored by unsteadily moving nanofluid with the occurrence of Sun rays and viscous dissipation. Tiwari-Das and Darcy-Forchheimer models are encompassed with convective heat transfer and mass suction/injection. Then, the non-linear higher-order set of ordinary differential equations was obtained from fundamental non-linear partial differential equations by using similarity transformation. Both semi-analytical and numerical strategies have been adopted. Comparisons with published articles have detected and observed similar outcomes. Accordingly, thermal Grashof number elevates nanofluid motion while postponing drag force creation. Permeability and Darcy’s number have publicized a contradictory trend in the nanofluid’s movement and temperature. Nanofluid’s temperature expands by incident solar radiation and Eckert number but not by absorption. There is less heat transfer rate by convective than conductive through magnifying magnetic field and nanoparticles’ concentration. Nanofluid constructed by Cu–H 2 O produces more drag force and less heat transfer rate than that of Cu–C 3 H 8 O 2 . Heat transfer from solar energy is applicable for cooking, heating water and producing electricity.
Analisis Penempatan Aparatur Sipil Negara pada Dinas Perikanan Kabupaten Lumajang

Field: Social Sciences (Social Sciences)

This study aims to determine the level of suitability of job specifications and the factors that influence the placement of State Civil Apparatus at the Fisheries Service of Lumajang Regency. This research uses descriptive qualitative method. This study explains the analysis of the distribution of employees who do not refer to the principle of placing the right person in the right position based on sources derived from scientific journals, books and official websites. The results showed that the placement of State Civil Apparatus at the Fisheries Service of Lumajang Regency using the theory proposed by Schuller and Jackson, namely knowledge, skills, abilities and personality were at a good level (appropriate) but not yet optimal, because of the influencing factors, namely leadership, human resources, regulations, and political positions.
Perioperative use of anti-EGFR antibodies in resectable and potentially resectable liver metastases

Field: Medicine (Health Sciences)

The radical resection of all visible disease manifestations can significantly improve the prognosis of patients with metastatic colorectal cancer, however, complete metastasectomy is initially possible only in a small proportion of patients, with many of them subsequently developing relapse. Aiming to increase the number of patients subject to radical intervention and to reduce the recurrence risk, preoperative chemotherapy (with or without subsequent adjuvant treatment) is widely used in routine practice. In the hope of increasing immediate effectiveness (increasing the proportion of patients subject to R0 resection) and the long-term results of treatment, preoperative chemotherapy is often accompanied with biological agents (anti-EGFR and anti-VEGF monoclonal antibodies) continued after surgery in some cases. However, despite the evidence of increased resectability, the impact of this approach on long-term treatment outcomes has not yet been determined. The analysis of recent studies in this area doubts the safety of perioperative use of anti-EGFR antibodies in patients with potentially curable metastatic colorectal cancer.
Effect of down-regulation of let-7c/g on triggering a double-negative feedback loop and promoting restenosis

Field: Medicine (Health Sciences)

Abstract Background: Excessive proliferation and migration of vascular smooth muscle cells (VSMCs) are the main causes of restenosis (RS) in diabetic lower extremity arterial disease (LEAD). However, the relevant pathogenic mechanisms are poorly understood. Methods: In this study, we introduced a "two-step injury protocol" rat RS model, which started with the induction of atherosclerosis (AS) and was followed by percutaneous transluminal angioplasty (PTA). Hematoxylin-eosin (HE) staining and immunohistochemistry staining were used to verify the form of RS. Two-step transfection was performed, with the first transfection of Lin28a followed by a second transfection of let-7c and let-7g, to explore the possible mechanism by which Lin28a exerted effects. 5-ethynyl-2΄-deoxyuridine (EdU) and Transwell assay were performed to evaluate the ability of proliferation and migration of VSMCs. Western blotting and quantitative real-time polymerase chain reaction (qRT-PCR) were performed to detect the expression of Lin28a protein and let-7 family members. Results: Using a combination of in vitro and in vivo experiments, we discovered that let-7c, let-7g, and microRNA98 (miR98) were downstream targets of Lin28a. More importantly, decreased expression of let-7c/let-7g increased Lin28a, leading to further inhibition of let-7c/let-7g. We also found an increased level of let-7d in the RS pathological condition, suggesting that it may function as a protective regulator of the Lin28a/let-7 loop by inhibiting the proliferation and migration of VSMCs. Conclusion: These findings indicated the presence of a double-negative feedback loop consisting of Lin28a and let-7c/let-7g, which may be responsible for the vicious behavior of VSMCs in RS.
Comparison of linear and widely linear processing in MIMO-FBMC systems

Field: Computer Science (Physical Sciences)

This paper carries out a comparison between two multi-stream techniques aimed for filter bank multicarrier (FBMC) systems based on the offset quadrature amplitude modulation (OQAM). The first option performs linear processing (LP) and, therefore, it does not take into account the non-circularity property of the transmitted symbols. The second technique considers the FBMC specificities and performs widely linear processing (WLP). With the aim of predicting which solution gives the best performance we have conducted a theoretical analysis that reveals that the technique based on the LP is able to achieve the lowest sum mean square error (MSE) at high SINR in channels with high coherence bandwidth. This holds true when the number of streams (S), and the number of transmit antennas (NT) and receive antennas (NR) are related as follows S = NR = 3, NT = NR. The numerical results show that the LP also gives the best performance in terms of BER if the aforementioned inequality is satisfied and the channel coherence bandwidth is substantially larger than the subcarrier spacing. If not, then the LP exhibits an error floor and the WLP may give better performance, especially at low noise regime.
Studies on the Performance of Penicillin Acylase Immobilized to GMA-NVP-MBAA Copolymer Support

Field: Chemical Engineering (Physical Sciences)

The beaded glycidyl methacrylate (GMA)Nvinyl2pyrrolidone (NVP)N, N′methylenebis(acrylamide) (MBAA) copolymers (GNM) were synthesized by inverse suspension polymerization and used as support for the immobilization of penicillin G acylase. The activity of enzyme immobilized on GNM was about 491 U/g, when the polymer was synthesized at w (NVP)/w (GMA) = 1/10 with 50% crosslinking agent. After it was used to hydrolyze penicillin G for 4 times, the activity of the immobilized enzyme reached relatively steady value (444 U/g) from 491 U/g, and was hardly changed in the following repeatedly use for 14 times.
Ulcerative colitis specific cytotoxic IgG-autoantibodies against colonic epithelial cancer cells.

Field: Medicine (Health Sciences)

Serum antibodies cytotoxic to the colon cancer cell line RPMI 4788 were studied in 42 patients with ulcerative colitis, 61 patients with Crohn's disease, 27 patients with other inflammatory diseases (disease-controls) and 22 healthy controls. Cytotoxicity of antibodies towards RPMI 4788 was studied by means of a chromium release assay using peripheral blood mononuclear leucocytes of healthy subjects as effector cells. Using a four hour antibody dependent cell mediated cytotoxicity assay sera from 29% of ulcerative colitis patients contained antibodies cytotoxic for the target, while only 3% of the Crohn's patients and 6% of the disease controls and non of the healthy controls were positive. When an 18 hour assay was applied, however, not only 40% of ulcerative colitis patients, but also 14% of Crohn's patients and 21% of disease controls were found positive. The reactive antibody in the four hour assay was mainly of the IgG class, which points at a classical antibody dependent cell mediated cytotoxicity mechanism. In the 18 hour cytotoxic assay IgG and particularly IgM antibodies were found to be reactive. This suggests that in the latter case other cellular cytotoxic mechanism might be involved. There was a significant inverse correlation between the appearance of the ulcerative colitis restricted IgG-anticolon epithelial cell antibodies (four hour assay) and the disease activity (p less than 0.01). Absorption studies showed that the reactive antigen is not specific for ulcerative colitis colonic tissue, but is similarly found in Crohn's bowel tissue, and to a lower extent in normal bowel, liver and kidney. The reactive antigen, however, could not be detected in brain and lymphoblastoid cells.
Between the Holy Text and Its Unholy Context: Polemical Overtones in Yefet’s Commentary on Genesis

Field: Arts and Humanities (Social Sciences)

This chapter scrutinizes Yefet's massive commentary on Genesis in order to verify whether Yefet was indeed able to completely refrain from polemicizing against specific individuals or religious movements, irrespective of the theoretical declaration about his genuine quest for the best interpretation and despite the ethos of anonymous citation. It also verifies the object of his critique, if it nonetheless turns out that he was prepared to temporarily desist from the translation of the words of Scripture and explanation of its meanings according to what its words require so as to enter into polemics. Finally, it addresses the question: why did Yefet in a limited number of cases, and contrary to his habit of anonymous quoting and avoiding polemics decide to cite certain opinions in order to refute them while mentioning the name of their authors. Keywords:genesis; religious movements; Yefet's commentary