jimnoneill/paper-to-field-training huggingface dataset:
Implementasi Model Project Based Learning (PjBL) dalam Meningkatkan Keterampilan Generik Sains Fisika

Field: Social Sciences (Social Sciences)

This research aims to improve generic science skills by using the Project Based Learning (PjBL) model. This research using the method of classroom action research (PTK) with 2 cycles. Each cycle consists of the stages of planning, implementing actions, observing/observing, and reflecting. The research subjects were class X MIPA 3 of SMAN 3 Selong with a total of 26 people. Data was collected using a test technique to see the increase from cycle 1 to cycle 2. The results showed an increase from cycle 1 to cycle 2 with the percentage of generic science skills from 60.97% to 76.72%, including the medium to high category. The results obtained indicate that there is an increase in generic physics skills by using the Project Based Learning (PjBL) model.
PhUSE De-Identification Working Group: Providing De-Identification Standards to CDISC Data Models

Field: Health Professions (Health Sciences)

In this era of Data Transparency and sharing data with researchers, companies are defining their processes and deidentification guidance in order to comply with data privacy regulations. In particular, it is possible for researchers to request access to data across sponsors and both the difference of data models and de-identification techniques may make the analyses cumbersome and error-prone. While the CDISC data models are now adopted in the industry, PhUSE launched in July 2014 a dedicated Working Group to define de-identification standards for CDISC data models starting with SDTM. Participants from Pharmaceuticals, CROs, Software Vendors, CDISC specialists, Data Privacy specialists and Academia have joined forces to define a set of rules against SDTM to provide the industry with a consistent approach to data deidentification and increase consistency across anonymized datasets. Each domains and variables holding potentially Personally Identifying Information (PII) have been rated in terms of impact on data privacy. Based on that rating the variables are allocated standard rules of de-identification, the rationale and the impact on data utility is documented., allocated rules to apply and their rationale and impact on data utility. This presentation will elaborate on the Working Group main findings, the current deliverables and the perspective to take this first initiative to the next stage.
Identifying Androgen Receptor-Independent Mechanisms of Prostate Cancer Resistance to Second-Generation Antiandrogen Therapy

Field: Medicine (Health Sciences)

Abstract : We hypothesize that GR mediates resistance to enzalutamide in advanced prostate cancer through transactivation of SGK1. In this proposal, we aim to further explore the relationship between GR, SGK1, and enzalutamide resistance through experimental manipulation of GR and SGK1 in our previously reported laboratory models of enzalutamide resistance. In this research period we have further expanded upon the relationship between GR and SGK1 in the context of enzalutamide-driven prostate cancer. We have generated CRISPR/Cas9 cell lines to test the importance of SGK1. Finally, we have used the recently published metastatic prostate cancer genomics dataset to identify a novel mechanism of enzalutamide resistance that correlates with the effects of SGK1 in our xenograft models. This project has the potential to identify a critical and druggable component of the GR program to enable a safer and more effective strategy for treating AR-independent enzalutamide-resistant prostate cancers.
L'Oeil-Cerveau: nouvelles histoires de la peinture moderne

Field: Arts and Humanities (Social Sciences)

This book offers a new philosophical history of modern painting in France from Delacroix to Cezanne, via Manet, Seurat and Gauguin. Basing itself on statements by the painters themselves, it reconstructs this history as a series of changes in the relationship between the eye and the brain. In particular, it charts what it calls the ‘denaturalisation' and ‘cerebralization' of the painter's eye, drawing upon a philosophical interpretation of Hyppolite Taine's psycho-physiological studies of hallucination. (The guiding proposition of Taine's writings is that every perception, every image, and every sensation are by their very nature hallucinatory.) It is argued that the ‘Eye-Brain' of the modern painter is best conceived as the vector of a ‘monism of sensation' that seeks to produce a ‘true hallucination' of the world. As such, it produces an experimental practice that is irreducible to relations between subject and object, as conventionally conceived. It invents a new form of the cerebral, freeing the eye from its character as a fixed organ and from its representational function. This experimentation finds its philosophical correlate in Goethe's interrogation of colour, from which the book sets out. The history of modern painting in France is thereby presented as a continuous destruction of systems of representation and an ever-renewed deconstruction of the notion of the image.
Case Study: Dose Response of Caffeine on 20-km Handcycling Time Trial Performance in a Paratriathlete

Field: Medicine (Health Sciences)

Caffeine’s (CAF) ability to influence upper-body exercise endurance performance may be related to an individual’s training status. This case study therefore aimed to investigate the ergogenic effects of CAF dose on 20-km time trial (TT) performance of an elite male paratriathlete (wheelchair user; age = 46 years, body mass = 76.9 kg, body fat = 25.4%, and handcycling ). The athlete completed four 20-km handcycling TTs on a Cyclus II ergometer under controlled laboratory conditions following the ingestion of 2, 4, and 6 mg/kg CAF or placebo (PLA). Blood lactate concentration, power output, arousal, and ratings of perceived exertion were recorded. Ingestion of 2, 4, and 6 mg/kg CAF resulted in a 2%, 1.5%, and 2.7% faster TT compared with PLA (37:40 min:s). The participant’s blood lactate concentration increased throughout all trials and was greater during CAF compared with PLA. There were no obvious differences in ratings of perceived exertion between trials despite different performance times. Baseline arousal scores differed between PLA and 4 mg/kg CAF (1 = low ), and 2 and 6 mg/kg CAF (3 = moderate ). Arousal increased at each time point following the ingestion of 4 and 6 mg/kg CAF. The largest CAF dose resulted in a positive pacing strategy, which, when combined with an end spurt, resulted in the fastest TT. CAF improved 20-km TT performance of an elite male paratriathlete, which may be related to greater arousal and an increased power output for a given rating of perceived exertion.
Research Article Eigenstructures of MIMO Fading Channel Correlation Matrices and Optimum Linear Precoding Designs for Maximum Ergodic Capacity

Field: Engineering (Physical Sciences)

The ergodic capacity of MIMO frequency-flat and-selective channels depends greatly on the eigenvalue distribution of spatial correlation matrices. Knowing the eigenstructure of correlation matrices at the transmitter is very important to enhance the capacity of the system. This fact becomes of great importance in MIMO wireless systems where because of the fast changing nature of the underlying channel, full channel knowledge is difficult to obtain at the transmitter. In this paper, we first investigate the effect of eigenvalues distribution of spatial correlation matrices on the capacity of frequency-flat and-selective channels. Next, we introduce a practical scheme known as linear precoding that can enhance the ergodic capacity of the channel by changing the eigenstructure of the channel by applying a linear transformation. We derive the structures of precoders using eigenvalue decomposition and linear algebra techniques in both cases and show their similarities from an algebraic point of view. Simulations show the ability of this technique to change the eigenstructure of the channel, and hence enhance the ergodic capacity considerably. Copyright © 2007 H. R. Bahrami and T. Le-Ngoc. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 1.
Interferometry with the European Very Large Telescope

Field: Physics and Astronomy (Physical Sciences)

In the present Very Large Telescope (VLT) linear array concept four independent telescopes of the 8-m class are coupled together. This offers the unique possibility to operate the telescopes as an optical and/or infrared long base-line interferometer. The first target for an interferometric operation is the infrared range from 5 to 20 μ m and later a gradual expansion to shorter wavelengths. In the interferometric mode the gain of the 8-m diam single apertures of the VLT is only given, if adaptive optics is used for a real-time partial or full phase compensation of the degradations due to atmospheric turbulence. When the condition atmospheric coherence area > telescope diameter is not fulfilled, adaptive optics is a technique to restore full coherence over the whole pupil. The gain for the SNR in interferometry goes at least with the inverse cube of the point spread function. Therefore, no other parameter can bring about such an improvement. The correction problem is extremely severe at visible wavelengths due to the high temporal and spatial frequencies of the fluctuations. Instead of several thousand subapertures required in the visible for a full correction, only 100-200 subapertures have to be corrected in the infrared case. Additional to the phasing of the individual telescopes, the whole array has to be phased. In a system with independently mounted telescopes the longitudinal position of the pupil images and the effects of pupil foreshortening have to be corrected in addition to the pure path-length correction.
A multi-fiber ferrule for harsh avionic environments

Field: Engineering (Physical Sciences)

Avionic systems commonly route data and control signals through optical fiber cables for their high bandwidth over longer distances and their immunity to electro-magnetic interference. The commercially available multi-fiber MT ferrule is used in some avionic applications, but its polymer construction restricts its use to non-harsh environments. Harsh environments continue to use single-fiber, size 16,29504 termini in D38999 connectors, and this substantially reduces connection density and increases connector cost. This paper describes a novel, multi-fiber Football Ferrule™ concept under development for harsh environments in avionics. The ferrule is rugged since it is constructed of austenitic stainless steel and aligned using a metal split sleeve. Furthermore, the Football Ferrule™ increases connection density since it is smaller than the MT ferrule. The ferrule's small size allows the connection of 12 optical fibers within a single ST connector, SC connector, or multiples of 12 fibers with multiple ferrules in D38999 connectors. Additionally, the metallic ferrule might be useful as an electrical contact. Finite element analysis was used to evaluate the compliance of the metallic Football Ferrule™ and split sleeve under torsional loads.
Effects of Graded Levels of Hemp Seed (Cannabis sativa L.) on Performance, Organ Weight and Serum Cholesterol Levels on Broilers

Field: Agricultural and Biological Sciences (Life Sciences)

Background: Hemp seed (HS) has high protein with good quality and more than 90% of its fats are polyunsaturated fatty acids. Objective: The objective of this experiment was to determine the effects of graded levels of HS on performance, organ weight (OW), and serum cholesterol levels on broilers. Methods: 192 male broiler chicks (1 d old-ROSS 308) were randomly assigned to a completely randomized design with 4 dietary treatments: control (without HS), 2.5, 5 and 7.5% HS in 4 replications (12 birds/pen). Weight gain (WG), feed intake (FI) and feed conversion ratio (FCR) were measured and calculated at the end of each wk. At the end of 6th wk, to determine serum lipids (1 bird/pen) and OW (2 birds/pen) were randomly selected. Results: WG on 0 – 21 d (p<0.01) and 0 – 42 d (p<0.05) were significantly affected by HS levels. Increasing dietary HS levels significantly decreased total cholesterol, LDL, VLDL, triglyceride and liver weight relativity percentage (p<0.05) and increased HDL (p<0.01) levels in serum. HS levels had no significant effect on WG 22 – 42 d, FCR, FI and other organs weight relativity percentage (p >0.05). Conclusion: In conclusion highest levels of HS used in this experiment could be apply to reduce serum cholesterol and saturated fatty acids and increasing meat quality to improve human health as target consumer.
Models of religion-related education in Germany, Switzerland and Austria and the topic of Islam

Field: Social Sciences (Social Sciences)

Regionality as a formative characteristic of religion-related education in Germany, Switzerland and Austria is the focus of the current project 'Models of Religious Education and the topic of Islam' ('MORE'). The project compares four different regional variants of religion-related education that are assigned to two competing models, denominational RE and non-denominational RE, by investigating how each of them presents the topic of 'Islam'. The comparison is carried out on the basis of qualitative research through interviews with teachers and pupils as well as lesson observations. Comparing regional variants of RE calls for a study design that is, on the one hand, attentive to regional characteristics while also reaching a degree of standardisation that allows for comparisons, on the other hand. Following trends in comparative education, the article describes the architecture of the MORE project as a type of collaborative cross-border research.
Studies on pelleted growth form of Aspergillus ochraceus in submerged cultures as a biocatalyst for canrenone 11#alpha#hydroxylation

Field: Chemical Engineering (Physical Sciences)

Morphology was manipulated by means of inoculum level and initial pH value.The physiological state of mycelial pellets was estimated according to the growth kintics,pH value,and 11α hydroxy-canrenone conversion ratio.It was found that more efficient biotransformation was performed with small and fluffy pellets.The highest 11α hydroxy-canrenone conversion ratio of 92% was achieved in 7L fermentor under the optimum conditions and the fermentation time was saved.
Vibro-acoustic behavior of partially submerged composite sandwich plates with negative Poisson’s ratio grids

Field: Engineering (Physical Sciences)

Composite sandwich structures demonstrate significant potential for applications in Marine structures due to their corrosion resistance, high specific strength, and lightweight characteristics. This paper explores the underwater vibro-acoustic characteristics of composite sandwich plates featuring negative Poisson’s ratio grids. The composite sandwich plate comprises orthotropic carbon fiber and glass fiber laminates, along with a periodic grating structure. The fundamental units of the grating structure are star grids, chiral grids, and concave hexagonal grids, respectively. The vibration and noise reduction performance of the negative Poisson ratio composite sandwich plate is affirmed through comparison with the traditional regular hexagonal composite sandwich plate. The chiral and concave hexagonal grids demonstrate outstanding noise reduction capabilities, achieving up to 25 dB, though their vibration damping performance is poor. In contrast, the star grid still exhibits high acoustic response peaks but maintains a relatively stable vibration damping performance of around 5 dB. Finally, the paper explores the effects of different parameters on the vibro-acoustic behavior of composite sandwich plates with negative Poisson ratio grids, including cell equivalent Poisson ratio, panel layup angle, and plate curvature.
One-Year Open-Label Study of Entacapone in Patients with Advanced Parkinson Disease

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The dropout at 1 year of our study was very high at 41%. Even though entacapone is indicated for advanced PD patients with motor fluctuation, the fluctuators commonly have dyskinesia and mental symptoms, which can become more troublesome with entacapone. In the patients with advanced PD, the clinical efficacy and side effects should be carefully considered in a long-term use of entacapone.
Kevlar KM2 Yarn and Fabric Strength Under Quasi-Static Tension

Field: Materials Science (Physical Sciences)

Abstract : Kevlar KM2, 600 denier, was Instron tested in quasi-static, uniaxial tension to determine its strength. Specimens included both single yarns and 68-yarn-wide, single-ply strips of plain-woven fabric (Style 706). Never-woven single-yarn speciens were tested with varying degrees of initial twist. Strength of the untwisted, never-woven yarn was 2.66 +/= 0.04 GPa. The twist multiplier was 1.2. Single warp-oriented and fill-oriented yarns were extracted from Style 706 fabric, tested, and found to have strengths of 2.06 +/= 0.01 and 2.20 % 0.05 GPa, respeptively. The single-ply fabric specimens of both warp and fill orientations were tested and found to have strengths of 2.23 +/= 0.04 and 2.67 +/= 0.04 GPa, respectively. The strength effects of weaving, finishing, yarn extraction, and inter-yarn contact are discussed.
LASIK-induced Corneal Changes after Correction of Hyperopia with and without Application of Mitomycin-C

Field: Medicine (Health Sciences)

Abstract

Background The study aimed to assess the role of intraoperative mitomycin-C (MMC) application during hyperopic LASIK correction (+1.00 D to +6.00 D) by examining topographic corneal changes and incidence of regression over a one-year follow-up period. Methods This comparative randomized control study included 136 eyes of 68 hyperopic patients divided into two groups; Group A included 68 eyes of 34 patients that had LASIK with the application of 0.02% MMC for 10 seconds on the stromal bed after excimer laser treatment, and group B included 68 eyes of 34 patients that had LASIK without MMC application. Uncorrected distance visual acuity (UDVA), refraction, keratometry and topography were recorded at 1st week and 1st, 3rd, 6th, and 12th months postoperation. Predictability and treatment efficacy were also recorded at the end of the follow-up period. Results Better predictability was noted in group A than in group B at the 6 month and 12 month follow-up visits, with a mean cycloplegic refraction SE of +0.5 ± 0.31 D in group A and +0.67 ± 0.39 D in group B at the 6 month visit, and +0.63 ± 0.37 D in group A and +0.89 ± 0.48 D in group B at the 12 month visit. The efficacy of the treatment at the end of the follow up period was better in group A than in group B. Group A showed fewer topographic corneal changes than group B. Conclusions Intraoperative MMC application during hyperopic LASIK achieves better predictability and efficacy and induces fewer topographic changes and lower regression rate of hyperopia during the first postoperative year. Trial registration: the Pan African Clinical Trial Registry PACTR201901543722087, on 29 January 2019.
Numerical study of the hazardous factors of a ﬁre in a passenger railway car

Field: Engineering (Physical Sciences)

This report presents the results of a numerical modelling of a ﬁre in a typical Bulgarian State Railways passenger compartment railway car using the PyroSim software product. The created numerical model was previously veriﬁed through experiments conducted on diﬀerent scales. This study examines two scenarios of ﬁre development – with the compartment door closed and with the compartment door open, in which the ﬁre occurred. The obtained dependencies of the change in time of two of the dangerous ﬁre factors – loss of visibility and carbon monoxide concentration, which in this case are the most dangerous, were analysed. The obtained results show what is the maximum time for evacuation from the railway car. With the compartment door closed, passengers have about 80 seconds more to evacuate under favourable conditions from the corridor of the railway car.
Rapidly sheared homogeneous stratified turbulence in a rotating frame

Field: Physics and Astronomy (Physical Sciences)

Rapid distortion theory is applied to stratified homogeneous turbulence that is sheared in a rotating frame. Insight into the stabilizing and destabilizing effects of the combined stratification and frame rotation is gained by considering initial fields that are two-dimensional, with the axis of independence aligned with the flow direction. For these conditions, we derive solutions for the Fourier components of the flow variables, and for one-point statistics in physical space. The analytical results are in qualitative agreement with the exact numerical solution for initially isotropic homogeneous turbulence, and they could be a reference point for the development of turbulence models.
Supporting strategic decision-making on the future campus with space utilisation studies: a case study

Field: Decision Sciences (Social Sciences)

Purpose Across the world, many universities are dealing with a pressure on resources, caused by both organisational developments and ageing campuses. Space utilization studies have a strategic role, providing information on how space is being used, thereby informing decisions about the type and scale of facilities that are needed. Design/methodology/approach This study reports on the space use measurements conducted at TU Delft over the past five years, complemented by their use to make decisions about the university's real estate portfolio. Findings The education spaces of the university are found to perform well in terms of frequency rates and can be improved in terms of occupancy rates. The information helped to support short- and long-term decision-making. The study places of the university have a satisfactory occupancy in some types of study places, while in others there is room for improvement. More research is needed here to understand the relationship between space norms and space use. Practical implications The space utilization studies have supported discussions with the student council and decision makers on which interventions are required and which current facilities meet students' needs best. Originality/value Not much space utilisation studies are reported in the academic literature, and those that do have several limitations. This study may serve as a best practice for benchmarking by other universities and as evidence in other research for the planned and actual use of university facilities.