jimnoneill/paper-to-field-training huggingface dataset:
Early and late side effects, dosimetric parameters and quality of life after proton beam therapy and IMRT for prostate cancer: a matched-pair analysis

Field: Medicine (Health Sciences)

Purpose: To compare early and late toxicities, dosimetric parameters and quality of life (QoL) between conventionally fractionated proton beam therapy (PBT) and intensity-modulated radiation therapy (IMRT) in prostate cancer (PCA) patients. Methods: Eighty-eight patients with localized PCA treated between 2013 and 2017 with either definitive PBT (31) or IMRT (57) were matched using propensity score matching on PCA risk group, transurethral resection of the prostate, prostate volume, diabetes mellitus and administration of anticoagulants resulting in 29 matched pairs. Early and late genitourinary (GU) and gastrointestinal (GI) toxicities according to Common Terminology Criteria for Adverse Events (CTCAE) and QoL based on EORTC-QLQ-C30/PR25 questionnaires were collected prospectively until 12 months after radiotherapy (RT). Associations between toxicities and dose–volume parameters in corresponding organs at risk (OARs) were modeled by logistic regression. Results: There were no significant differences in GI and GU toxicities between both treatment groups except for late urinary urgency, which was significantly lower after PBT (IMRT: 25.0%, PBT: 0%, p = .047). Late GU toxicities and obstruction grade ≥2 were significantly associated with the relative volume of the anterior bladder wall receiving 70 Gy and the entire bladder receiving 60 Gy, respectively. The majority of patients in both groups reported high functioning and low symptom scores for the QoL questionnaires before and after RT. No or little changes were observed for most items between baseline and 3 or 12 months after RT, respectively. Global health status increased more at 12 months after IMRT (p = 0.079) compared to PBT, while the change of constipation was better at 3 months after PBT compared to IMRT (p = 0.068). Conclusions: Overall, IMRT and PBT were well tolerated. Despite the superiority of PBT in early constipation and IMRT in late global health status compared to baseline, overall QoL and the risks of early and late GU and GI toxicities were similar for conventionally fractionated IMRT and PBT.
Assessing the Level of Pedagogical Mentoring Activities among Early Childhood and Primary School Teachers in Plateau State

Field: Social Sciences (Social Sciences)

This study assessed the level of pedagogical mentoring activities among early childhood care and education (ECCE) and primary school teachers in Plateau State, Nigeria. Using a survey design, data was collected from 100 primary and ECCE teachers across the three senatorial zones through a five-point Likert scale titled “Teacher Mentoring Assessment Questionnaire (TMAQ)”. The findings revealed a significant gap in mentoring practices, with only 14% of teachers participating in any mentoring relationship and 0% in formal mentoring programs. All existing mentoring relationships were informal, naturally developed, and lacked documentation, formal goals, or structured components. Despite limited participation, mentoring relationships demonstrated strong cultural responsiveness, with high scores for respecting traditional values (M=4.00) and understanding cultural contexts (M=4.00). However, institutional support was critically lacking across all dimensions, with universal “strongly disagree” responses for dedicated time, training, resources, and recognition systems. Notably, teachers who participated in mentoring relationships consistently reported higher results compared to non-mentored teachers: job satisfaction (+1.26), teaching confidence (+0.99), new strategy implementation (+0.93), and retention (+1.10). The study concludes that while mentoring shows positive potential for teacher development and retention, significant implementation gaps exist. Recommendations include establishing structured mentoring programs, creating institutional support systems, and leveraging existing cultural strengths while adding formal components to maximize professional development impact.
Is the Bowl Championship Series a Cartel? Some Evidence

Field: Economics, Econometrics and Finance (Social Sciences)

The cartel view of the Bowl Championship Series (BCS) implies that it creates an advantage for automatic qualifying (AQ) member schools relative to other Division IA/FBS schools in recruiting the best players and hiring other inputs. The resulting playing-field advantage should produce more wins over “outsiders.” Weaker AQ schools benefit relatively more because previously they had competed more closely with outsiders for players. The evidence generally supports the cartel view. The AQ BCS schools and conferences have significantly increased their win percentage against outsiders. Also, the weaker AQ schools have performed better against the top tier, and have shown the greatest improvement against outsiders.
Austen's fans and fans' Austen

Field: Arts and Humanities (Social Sciences)

Abstract A corpus of Jane Austen's fanfic is constructed from sequels published in print and on line; it is then compared with a corpus of Austen's own writing, as well as one of contemporary romance fiction. Through analysis of the corpora, the “vertical intertextuality” of Austen's text and the fanfic corpus, and the “horizontal intertextuality” of contemporary romance fiction corpora and the fanfic corpus are articulated. The results illustrate that, although claiming to emulate her writing faithfully, Austen's fans reconstruct a modern Austen who is writing contemporary romance fiction through the “old” characters such as Elizabeth and Darcy. The different “Austens” emerging from this corpus research and other scholars' reading of Austen suggest that the death of the “Author” is only part of the story: we see not only the Author's death and the birth of the Reader, but a ghostly projection of a new “Author” in the reader's cultural context.
Acquisitions of safety-net hospitals from 2016–2021: a case series

Field: Health Professions (Health Sciences)

Abstract Safety-net hospitals have recently become targets of acquisition by health systems with the stated purpose of improving their financial solvency and preserving access to safety-net services. Whether acquisition achieves these goals is unknown. In this descriptive case series, we sought to determine the factors that contribute to safety-net hospital acquisition, and identify whether safety-net services are preserved after acquisition. We examined 22 acquisitions of safety-net hospitals from 2016 to 2021 and described characteristics of the acquired safety-net hospitals, their acquiring systems, and the operational fate of acquired hospitals. Relative to other hospitals in the same Hospital Referral Region in the year prior to acquisition, acquired safety-net hospitals tended to be smaller and have lower occupancy rates. Acquiring systems were geographically concentrated, with only 6 of 20 systems operating in more than 1 state. Safety-net hospitals frequently offered typical safety-net services prior to acquisition. However, after acquisition, 2 of the 22 acquired safety-net hospitals lost safety-net services, 3 hospitals ceased inpatient services, and 1 hospital closed entirely. These findings suggest that acquisition of safety-net hospitals may be associated with trade-offs related to the provision of safety-net services for the communities that stand to benefit from them most.
Study on Needs Analysis of Family Multiliteracy Competence from Program Keluarga Harapan

Field: Social Sciences (Social Sciences)

Yogyakarta is considered a very liveable area. However, there are still underlying problems, including low wages and poverty. The goal of the Program Keluarga Harapan (PKH) is to empower, because it does not only focus on providing assistance, but also on changing the community’s mindset. This study aimed to carry out a needs analysis, to understand the multiliteracy skills of beneficiary families. As mentioned above, the help provided by this program is not only in the form of bestowals, but also through efforts to increase empowerment. Data were collected through a qualitative online survey, observations and interviews. Based on the findings, it can be concluded that the Family Development Session served as a form of non-formal education for families. The findings on the literacy of beneficiary families showed that there was insufficient understanding of child care and learning assistance, financial management and entrepreneurial motivation. Participants had difficulty understanding the material presented. Keywords: empowerment, family, needs analysis, multiliteracy, Program Keluarga Harapan
Changes of anthocyanin content in Hongyang kiwifruits and effects of girdling and ABA on its accumulation.

Field: Agricultural and Biological Sciences (Life Sciences)

The changes of anthocyanin content and the influences of girdling and spraying abscisic acid (ABA) on anthocyanin content in kiwifruits (Actinidia chinensis 'Hongyang') were studied. The anthocyanin could be detected on June 5,and the anthocyanin content increased rapidly from July 27 to August 22,appeared to be reaching a maximum value on September 4,and then decreased a few. The anthocyanin content was significantly increased with girdling on bearing shoots and spraying ABA. Furthermore,wider girdling (range in 1/3 to 1/1 of shoot diameter) and higher treatment concentration of ABA (500-3 000 mg·L-1) resulted in higher anthocyanin contents.
Developing of innovative and cool mobile applications on the Googles Android powered devices 6

Field: Computer Science (Physical Sciences)

Mobile devices in recent years have grown to become an integrated part of our lives. There has been a growing number of people owning these devices and to many of us, a mobile device has very much become a necessity. It is no longer a device merely for communication but a device that provides myriad number of functionalities to users via mobile applications. This project aims to design and develop a mobile application that provides online shopping services for customer. It allows customers to search for groceries to purchase as well as buying promotional items. This application enables customers to purchase in bulk with friends and neighbors via social network platform to reduce the delivery charges. Customers will also be able to share and comment on the purchased groceries with their friends and neighbors. This application also provides an interface for suppliers to manage their products and customer orders. It allows suppliers to promote their sales by sending notification to customers on the latest promotions. In general, the application has been developed successfully on the Android platform and has effectively enhanced the online shopping experience for users with its comprehensive functionalities and features.
Local Wisdom: A Reflection of Creativity & Innovation Through Usungan Practice in Sarawak Coastal Community

Field: Arts and Humanities (Social Sciences)

The Sarawak coastal community consists of several divisions, districts and villages such as Kabong, Pusa, Spaoh, Belawai, Beladin, Maludam, Dalat and many more. A research trip has been conducted from 19-25 November 2018 in Kabong to document a rare practice by the coastal community, The marching of the Usungan. The event was held to celebrate a large group of children who completed their studies in the Al-Quran recitals. It is unique practice or tradition and it is only existing in the Borneo Island. Especially, Sarawak coastal areas continue to maintain and preserve it. Through the very interesting design of the Usungan, the Malay people of Sarawak has proven to have created their creativity and innovation. It has been stated that this practice has existed for more than 100 years ago. It is a privilege for the students or children to celebrate and, to encourage the younger generation to be successful and it is a kind of positive reinforcement for them. The Usungan also reflects the local wisdom of the people in art and design. Among the designs are aircrafts, cars, houses, mosques, boats, flowers, fishes and so on. Every design has their own story that reflects every single student who requested it. However, this practice requires the support of various parties, especially from the government, to continue and preserve it. As time goes by, some cultural heritage will be lost if no preservation effort of this practice starts from today. There are no complete and proper documentation of the design of the Usungan or any similar practice for the next generation references. Through Usungan, it shows that community knowledge in art and design in ways that can benefit the community and pass on. The event was held to celebrate a large group of children who completed their studies in the Al-Quran recitals. It is a unique practice or tradition and it only exist in the Borneo Island. Especially, Sarawak coastal areas continue to maintain and preserve it. Through the very interesting design of the Usungan, the Malay people of Sarawak has proven to have created their creativity and innovation.
Tumor cell lysis and synergistically enhanced antibody-dependent cell-mediated cytotoxicity by NKG2D engagement with a bispecific immunoligand targeting the HER2 antigen

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Natural killer group 2 member D (NKG2D) plays an important role in the regulation of natural killer (NK) cell cytotoxicity in cancer immune surveillance. With the aim of redirecting NK cell cytotoxicity against tumors, the NKG2D ligand UL-16 binding protein 2 (ULBP2) was fused to a single-chain fragment variable (scFv) targeting the human epidermal growth factor receptor 2 (HER2). The resulting bispecific immunoligand ULBP2:HER2-scFv triggered NK cell-mediated killing of HER2-positive breast cancer cells in an antigen-dependent manner and required concomitant interaction with NKG2D and HER2 as revealed in antigen blocking experiments. The immunoligand induced tumor cell lysis dose-dependently and was effective at nanomolar concentrations. Of note, ULBP2:HER2-scFv sensitized tumor cells for antibody-dependent cell-mediated cytotoxicity (ADCC). In particular, the immunoligand enhanced ADCC by cetuximab, a therapeutic antibody targeting the epidermal growth factor receptor (EGFR) synergistically. No significant improvements were obtained by combining cetuximab and anti-HER2 antibody trastuzumab. In conclusion, dual-dual targeting by combining IgG1 antibodies with antibody constructs targeting another tumor associated antigen and engaging NKG2D as a second NK cell trigger molecule may be promising. Thus, the immunoligand ULBP2:HER2-scFv may represent an attractive biological molecule to promote NK cell cytotoxicity against tumors and to boost ADCC.
Original Article Traditional Chinese medical herbs staged therapy in infertile women with endometriosis: a clinical study

Field: Medicine (Health Sciences)

Background: Endometriosis is a common gynecological disease defined as the presence of endometri - oid tissue (glands and stroma) outside the uterus. About 30 to 40% patients with endometriosis are infertile. In traditional Chinese medical system, endometriosis associated infertility is mostly caused by kidney deficiency and blood stasis. The herb of reinforcing kidney and removing blood stasis is designed to treat the disease. Material and methods: All the 80 up-to-standard patients were divided into two different groups exactly according to the random principle. They were treated with hormone and traditional Chinese medical herb separately. After half year's therapy, all the patients received one year's follow-up. Their transvaginal ultrasonographic changes, serum hormone levels and pregnancy rate were recorded to analysis the effect. Results: No significant difference happened in two groups' demographic and clinical characteristics (P > 0.05). After the treatment, the effect on serum hormone levels and specific markers are significant ( P < 0.05). The transvaginal ultrasonographic changes were positive, too. The text on hepatic and renal function confirmed to the safety of the herb. Compared to hormone therapy, the traditional Chinese medical herb is safe and effective for endometriosis patients with infertility. Conclusion: Compared with hormone therapy, traditional Chinese medical herb's two-staged therapy is effective and safe for endometriosis patients with infertility.
Pressure coefficients for evaluating wind loads on large roofs: Comparison between Database-Assisted Design and Italian standards

Field: Engineering (Physical Sciences)

In the last decade, the Database-Assisted-Design methodology has emerged as a powerful approach to estimate structural wind loads and as an alternative to prescriptive design standards, in particular for Low-Rise Buildings (e.g., Simiu et al., 2003). This work examines the applicability of this approach to wind load analysis and design as an alternative to the prescriptions currently included in the Italian design standard. In this paper, mean pressures coefficients on large roofs of industrial buildings are examined and compared to the recommendations of the current Italian national design guidelines (CNR-DT 207/2008).
Cost–effectiveness of fractional flow reserve-guided percutaneous coronary intervention

Field: Medicine (Health Sciences)

In recent years, fractional flow reserve (FFR) has become accepted as a clinically effective tool for guiding decisions about percutaneous coronary intervention (PCI). FFR poses a unique alternative to stress testing or angiography-guided PCI, in that it can interrogate the ischemic potential of an individual vessel on an impromptu basis once an angiogram is in progress, offering immediate data for decision making. With its recent greater adoption across the USA, its cost–effectiveness has become an important consideration. There have been a few key analyses over the last decade demonstrating the cost–effectiveness of FFR-guided PCI; we review the major cost–effectiveness analyses, showing the economic utility of FFR-guided PCI for the modern interventionalist.
The Effect of Age on Criminal Processing

Field: Social Sciences (Social Sciences)

Abstract This article uses data on the prefile diversion review of 5,715 drug offenders to explore the effect of age on criminal processing outcomes. Specifically, the study asks whether older offenders were treated more leniently than younger offenders and to what extent any age-based preferential treatment extended to race/ethnic minorities. Hypotheses on the treatment of younger and older offenders generally and for racial/ethnic groups are tested. The results for the entire sample indicate a positive effect which begins at about age 52. Moreover, there is an elderly effect for whites and Native Americans, but not for blacks and Hispanics. These results introduce a significant caveat in the ubiquitous precept that all older offenders are treated more leniently in criminal processing. They support previous policy questions regarding how much racial/ethnic minority offenders benefit from generally accepted preferential treatment for the older offender. The issues which arise from the preferential treatment has implications for social policy generally andsocialworkersin particular.
An Overview of the ICASSP Special Session on AI Security and Privacy in Speech and Audio Processing

Field: Computer Science (Physical Sciences)

Perceiving and producing speech and audio signals are the basic ways for humans to communicate with each other and know about the world. Benefiting from the advancement of Big Data, signal processing, and Artificial Intelligence (AI), intelligent machines have been rapidly developed to process speech and audio signals for assisting human life. Deep learning has been demonstrated to achieve excellent performance based on large amounts of data streams. In the meanwhile, the problems of security vulnerability and privacy leakage appear along with the booming technologies. Systems with security and privacy problems can expose users' personal information to danger and cause users' distrust. To facilitate technology development in tackling the aforementioned issues, the special session on "AI security and privacy in speech and audio processing" was organised at ICASSP 2023. In this study, we provide a comprehensive overview of the invited high-quality contributions at the special session. We further discuss the current research challenges, and point out potential avenues for future works. This work is expected to summarise the research advancements and inspire more innovative studies in this area.
Rhodium‐Catalyzed Atroposelective Construction of Indoles via C−H Bond Activation

Field: Chemistry (Physical Sciences)

Abstract Reported herein is the rhodium(III)‐catalyzed C−H activation of anilines bearing an N ‐isoquinolyl directing group for oxidative [3+2] annulation with four classes of internal alkynes, leading to atroposelective indole synthesis via dynamic kinetic annulation with C‐N reductive elimination constituting the stereo‐determining step. This reaction proceeds under mild conditions with high regio‐ and enantioselectivity and functional group compatibility.
Cereal Terms in the DOST Record

Field: Arts and Humanities (Social Sciences)

This chapter considers what the terminology of cereal crops and their products in the Dictionary of the Older Scottish Tongue tell us about the language and diet of Lowland Scotland in the period. It presents a vocabulary of cereal varieties such as corn, bere, ait/ate, and mele/meil. It then describes forms of consumption and the cooking of cereals.
Acute pancreatitis: A rare presenting feature of Henoch Schonlein purpura

Field: Medicine (Health Sciences)

Abstract: Pancreatitis is a rare manifestation of Henoch Schonlein purpura (HSP). Herein we report a 3‐year‐old girl presented with acute pancreatitis that developed characteristic rash for HSP at the fifth day of clinical onset. Abdominal pain which is the most frequent sign of gastrointestinal involvement can be also explained by acute pancreatitis. Although clinical features of pancreatitis may be encountered after the onset of the typical rash, pancreatitis can also occur as a presenting feature. This rare presentation of HSP is discussed to emphasise the clinical features, presentation and outcome of pancreatic involvement.
William Morton Wheeler1

Field: Agricultural and Biological Sciences (Life Sciences)

William Morton Wheeler was born on March 19, 1865, at Milwaukee, Wisconsin. His interest in natural history was aroused at a very early age. While on a visit to his uncle in the Wisconsin country, when he was 9 years old, Wheeler saw a spider ensnare a moth in its web, and the explanation of this incident by his nature-loving uncle made so deep an impression on the boy that he became importunate for more nature lore. Subsequent observations of the habits of sexton beetles and burrowing wasps launched his career into entomological channels.
ChemInform Abstract: γ‐Lactones upon Double Nucleophilic Additions of Bis(TMS)ketene Acetals to π‐Systems and Access to New Cytotoxic Endoperoxide Lactones

Field: Chemistry (Physical Sciences)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.