jimnoneill/paper-to-field-training huggingface dataset:
Association of Pulse Wave Velocity With Chronic Kidney Disease Progression and Mortality

Field: Medicine (Health Sciences)

Patients with chronic kidney diseases (CKDs) are at risk for further loss of kidney function and death, which occur despite reasonable blood pressure treatment. To determine whether arterial stiffness influences CKD progression and death, independent of blood pressure, we conducted a prospective cohort study of CKD patients enrolled in the CRIC study (Chronic Renal Insufficiency Cohort). Using carotid–femoral pulse wave velocity (PWV), we examined the relationship between PWV and end-stage kidney disease (ESRD), ESRD or halving of estimated glomerular filtration rate, or death from any cause. The 2795 participants we enrolled had a mean age of 60 years, 56.4% were men, 47.3% had diabetes mellitus, and the average estimated glomerular filtration rate at entry was 44.4 mL/min per 1.73 m 2 . During follow-up, there were 504 ESRD events, 628 ESRD or halving of estimated glomerular filtration rate events, and 394 deaths. Patients with the highest tertile of PWV (>10.3 m/s) were at higher risk for ESRD (hazard ratio [95% confidence interval], 1.37 [1.05–1.80]), ESRD or 50% decline in estimated glomerular filtration rate (hazard ratio [95% confidence interval], 1.25 [0.98–1.58]), or death (hazard ratio [95% confidence interval], 1.72 [1.24–2.38]). PWV is a significant predictor of CKD progression and death in people with impaired kidney function. Incorporation of PWV measurements may help define better the risks for these important health outcomes in patients with CKDs. Interventions that reduce aortic stiffness deserve study in people with CKD.
Comments on “Removal of SO2 from Industrial Effluents by a Novel Twin Fluid Air-Assist Atomized Spray Scrubber”

Field: Chemical Engineering (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVCorrespondenceNEXTComments on "Removal of SO2 from Industrial Effluents by a Novel Twin Fluid Air-Assist Atomized Spray Scrubber"Amitava Bandyopadhyay*View Author Information Department of Chemical Engineering, University of Calcutta, 92 APC Road, Kolkata 700 009, India* To whom correspondence should be addressed. E-mail: [email protected]Cite this: Ind. Eng. Chem. Res. 2009, 48, 11, 5563–5564Publication Date (Web):May 7, 2009Publication History Published online7 May 2009Published inissue 3 June 2009https://pubs.acs.org/doi/10.1021/ie801789dhttps://doi.org/10.1021/ie801789darticle-commentaryACS PublicationsCopyright © 2009 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views327Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (44 KB) Get e-AlertscloseSUBJECTS:Atmospheric chemistry,Computer simulations,Fluids,Liquids,Mass transfer Get e-Alerts
In the Wrong Place at the Wrong Time: Identifying Spatiotemporal Co-occurrence of Bycaught Common Dolphins and Fisheries in the Bay of Biscay (NE Atlantic) From 2010 to 2019

Field: Environmental Science (Physical Sciences)

The first Unusual Mortality Event (UME) related to fishing activity along the Atlantic coast recorded by the French Stranding Network was in 1989: 697 small delphinids, mostly common dolphins, washed ashore, most of them with evidence of having been bycaught. Since then, UMEs of common dolphins have been observed nearly every year in the Bay of Biscay; unprecedented records were broken every year since 2016. The low and unequally distributed observation efforts aboard fishing vessels in the Bay of Biscay, as well as the lack of data on foreign fisheries necessitated the use of complementary data (such as stranding data) to elucidate the involvement of fisheries in dolphin bycatch. The aim of this work was to identify positive spatial and temporal correlations between the likely origins of bycaught stranded common dolphins (estimated from a mechanistic drift model) and fishing effort statistics inferred from Vessel Monitoring System (VMS) data on vessels &gt;12 m long. Fisheries whose effort correlated positively with dolphin mortality areas after 2016 included French midwater trawlers, French Danish seiners, French gillnetters, French trammel netters, Spanish bottom trawlers, and Spanish gillnetters. For the French fleet only, logbook declarations, sales, and surveys carried out by Ifremer were integrated into fishing effort data. Six fleets were active in common dolphin bycatch areas at least twice between 2016 and 2019: gillnetters fishing hake, trammel netters fishing anglerfish, bottom pair trawlers fishing hake, midwater pair trawlers fishing sea bass and hake, and Danish seiners fishing whiting. Except for changes in hake landings in some fisheries, there were no notable changes in total fishing effort practice (gear or target species) based on the data required by the ICES and Council of the European Union that could explain the large increase in stranded common dolphins recorded along the French Atlantic coast after 2016. Small scale or unrecorded changes could have modified interactions between common dolphins and fisheries, but could not be detected through mandatory data-calls. The recent increase in strandings of bycaught common dolphins could have been caused by changes in their distribution and/or ecology, or changes in fishery practices that were undetectable through available data.
Plant Regeneration Through Tissue Culture Of Pear Millet (<i>Pennisetum Glaucum</i> (L) R.)

Field: Agricultural and Biological Sciences (Life Sciences)

Many problems were kipt out with immature embryos and shoot explants pieces used ; principally : Calli were initiated in plant flowering periode (every 110 days), and the low percentage of embrogenesis what either the source used. So for Pennisetum Glaucum, new embryogenic calli sources were explored from calli initiation to fertile plant regeneration achieving. About 90 % of dissected shoot apices, seedlings and seeds developed calli. From meristems position, 6 mm of shoot and 20 mm of root developed 50 to 100 % of calli. No embryogenic calli were obtained from root. More than 80 % of dissected apices led to embryogenic calli. Maintained on MS(1. 1. 2,5), MS(5) and N6(1.100.25) culture media, calli embryogenic potential and fertile plants regeneration were conserved for more than 12 months. Characteristics of regenerated plants were similar to control. It appears that dissected shoot apex was a new appropriate tool in tissue culture.Les difficultés liées à utilisation de l\'embryon immature et des explants de tige dans les cultures de tissus sont nombreuses ; dont l\'initiation de cal qui ne se fait que pendant la floraison, pour l\'embryon immature, soit chaque 110 jours, et le faible pourcentage de l\'embryogenèse. Pour Pennisetum Glaucum , de nouvelles sources de cals embryogènes ont été explorées depuis l\'initiation de cal jusqu\'à l\'obtention de plante fertile. Environ 90 % des méristèmes apicaux, des germes et des grains ont développé des cals. A partir des méristèmes, seuls 6 mm de tige et 20 mm de racine ont développé des cals avec un taux de 50 à 100 %. La racine n\'a développé aucun cal embryogène. Plus de 80 % des cals de méristèmes apicaux étaient embryogènes. Les cals maintenus sur MS(1.1.2,5), MS(5) et N6(1.100.25), sont restés embryogènes et ont produit des plantes fertiles pendant au moins 12 mois. Les plantes régénérées ont des caractéristiques semblables aux plantes témoins. Il ressort que le méristème apical est un nouveau matériel approprié pour la culture de tissus. Keywords: Tissue culture, culture medium, callus induction, shoot apex, Pennisetum Glaucum, Côte d\'Ivoire.; culture de tissus, milieu de culture, induction de cal, méristème apical, Pennisetum Glaucum, Côte d\'Ivoire.Agronomie Africaine Vol. 15 (3) 2003: pp. 105-121
Type 2 diabetes and physical activity: barriers and enablers to diabetes control in Eastern India

Field: Health Professions (Health Sciences)

Abstract Introduction: Type 2 diabetes (T2D) has tremendous morbidity burden owing to disease management and complication prevention. Behavior modification identified as a key to management includes healthy diet and regular physical activity (PA). This study aims to identify patterns and preferences of PA of T2D patients and explore perceived enablers and barriers for diabetes control in Bhubaneswar. Methods: Cross-sectional, facility-based study conducted in the private sector from June to August 2014 recruited 321 T2D patients using semi-structured questionnaires. Descriptive statistics and associations of PA were computed. Results: Almost two-thirds of patients (59%) were reported performing PA frequently. Majority patients cited walking as the most preferred mode of PA (79%) with 41% performing PA daily. Actual versus perceived weight was a complete mismatch with most patients misjudging their weight. Reasons for enabling PA included ‘controlling diabetes’ and ‘doctor’s advice’ as key factors, while ‘lack of time’ and ‘unwillingness’ were main barriers among inactive patients. Conclusion: Counseling on PA by physicians during routine visits, along with tailored or patient-specific interventions should be considered. Focus on social support for positive behavioral changes and motivation play a central role in diabetes control.
Case 32-1988

Field: Medicine (Health Sciences)

Presentation of CaseA 47-year-old man was admitted to the hospital because of jaundice.He was in a stable state of health until 32 months earlier, when he consulted a physician because of a respiratory tract infection and anemia was found. Colonoscopic examination showed a tumor in the right side of the colon. A right colectomy was performed at another hospital. Microscopical examination of the excised tumor revealed a poorly differentiated adenocarcinoma of the signet-ring-cell type, with invasion of the submucosa and metastasis to one of five pericolonic lymph nodes; the tumor was classified as Dukes' class C. The patient . . .
Cell viability of fine powders in hybrid resins and ceramic materials for CAD/CAM

Field: Dentistry (Health Sciences)

Resin blocks and ceramic blocks for CAD/CAM crowns were cut into powders and separated into three particle size groups. Oxidative stress and cell viability were measured in 3T3 and FRSK cells. The results of cytotoxicity tended to be slightly higher for resin than for ceramics. The values also increased as the particle size decreased in the powders. In addition, incorporation into cells was frequently observed under SEM, suggesting that the particle size of easily incorporated dust is different among cell types. Fluorescence-activated cell sorter (FACS) showed an increase in apoptosis and a decrease in cell viability in most of the sample groups compared to the control group. Hematoxylin and eosin staining of the cells showed deep staining of the nuclei in the sample groups. It was found that oxidative stress cell viability and apoptosis appeared differently depending on the size of the particles and the type of cells.
Effect of leisure-time physical activity in controlling hypertension: a systematic review and meta-analysis protocol

Field: Medicine (Health Sciences)

Introduction Hypertension is a major risk factor for cardiovascular diseases. In 2015, over 1.13 billion individuals worldwide had hypertension. Globally, it results in 10.8 million deaths every year. Around half of the individuals do not continue treatment with medicine to control blood pressure. Physical activity, a non-pharmacological option of treatment, reduces blood pressure. We aim in this research to examine the effect of leisure-time physical activity in controlling blood pressure. Methods and analysis We will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses to conduct this study. We will perform a systematic search in Medline/PubMed, Embase, Scopus, Web of Science, Physical Education Index (ProQuest) and CENTRAL (the Cochrane Library). Both experimental and observational studies will be included. The study population would be people with hypertension. Two reviewers will perform screening of the articles, bias assessment and data extraction independently. We will use the Joanna Briggs Institute Critical Appraisal Tools to assess the risk of bias. We will conduct a meta-analysis if it is applicable. Ethics and dissemination The results will be published in peer-reviewed journals and presented at relevant scientific seminars and conferences. Ethical approval is not applicable. PROSPERO registration number CRD42021260751.
Kmeans Clustering Based Ink Mismatch Detection

Field: Computer Science (Physical Sciences)

Forgery investigation and detection has been a relevant topic of interest for human beings since ages. Important messages written and transported by kings in old ages were sealed with signatures and stamps to achieve this purpose. But with the advent of digital technology, forgery detection has become even more important since tools for forgery have become vast as well. In this paper a technique based on pixel clustering has been introduced for detection of modification, alteration or forgery done with a different ink color pen. Hyperspectral images are used for ink mismatch detection in a handwritten note. We propose ink classification based on pixel intensities values present in all the bands of hyperspectral images of the handwritten note. Our proposed technique is quite simple yet effective in detecting ink mismatch with relatively high accuracy.
LiFiX: A fully bidirectional CMOS light communication device: Multichannel dedicated device for high bandwidth secured wireless data transmission

Field: Engineering (Physical Sciences)

LiflX, is a fully integrated Li-Fi CMOS device. It contains 64 emission-reception cells and architectured in a similar way as a memory array with bitlines and wordlines to read and write data via access transistor of each cell. Each row in the array is specific in terms of commutation frequency and each column is specific in terms of wavelength. Individual cells contain one LED for light emission and one photodiode for light reception. Device is fully bi-directional, can reach bandwidth of 26 Gb/s for 64 cells and has high level of data transmission security via frequency hopping.
The influence of user characteristics on performance in database querying

Field: Computer Science (Physical Sciences)

Although user characteristics influence MIS performance, little existing evidence indicates whether user characteristics influence performance in database querying tasks. This research maps out the results of a laboratory experiment in which participants generated SQL queries to retrieve information and satisfy typical information requirements. Prior to the experiment, demographic, personality, and cognitive style profiles of the participants were gathered, and these profiles were used to make the treatment groups as equal as possible. This research examined the influence of query complexity, experience, education, GPA, personality, and cognitive style on accuracy and efficiency of query formulation. The results revealed that as query complexity increased, performance declined. Participants with more experience, education, and higher GPAs, and those with intuitive-type and thinking-type cognitive styles performed queries more accurately and efficiently.
Closed-chest massage: an effective resuscitative procedure for the maintenance of the circulation during cardiac arrest.

Field: Medicine (Health Sciences)

Reports of clinical benefits of closed-chest cardiac resuscitation refute recently published studies contesting its effectiveness.Our experimental investigations demonstrate that closed-chest massage is able to achieve adequate cerebral circulation and oxygenation during cardiac arrest.Clinical studies indicate that a significant number of coronary patients can be saved if a monitor system is used to warn of the onset of ventricular fibrillation or arrest. To be successful, closed-chest resuscitation must be instituted within the four-minute limit after onset of cardiac arrest. When ventricular fibrillation occurs, electrical countershock is usually obligatory. Cardiac pacemaking is a specific necessity for patients with ventricular arrest.
Research of Modern Information Technology on Tree Growth Management Decision Making Model

Field: Agricultural and Biological Sciences (Life Sciences)

Tree growth management decision-making model can simulate growth management of tree and perform quantitative analysis of tree growth conditions.This paper explores the feasibility of modern information technology in management assessment of tree growth, information technology include neural network, ontology and expert system technology, then ontology technology is used to establish ontology database and knowledge base of tree growth management resource, the growth simulation and tree growth management ontology technology are used to build simulation models of tree growth, then expert systems and neural network technology are combined to simulate tree growth development process of decision-making model.The practice has proved that the research can not only predict the growth conditions of tree and dynamic grasp the growth process of the tree, but also can provide theoretical basis for the analysis and evaluation of tree growth management, greatly improving the level of tree growth management.
Spent Nuclear Fuel and HLW Storage towards Disposal - Challenges and Perspectives of an Integrated Approach -

Field: Engineering (Physical Sciences)

This paper describes and discusses the major challenges of spent fuel management in Germany after the phase-out of nuclear electricity generation was decided in 2011 and a new repository siting procedure was implemented in 2013. Consequences from those decisions which were legally founded by amendments of the German Atomic Energy Act (AtG) result in the need to transfer all remaining spent fuel from limited reactor operation (last reactor shutdown until the end of 2022) into casks for subsequent dry interim storage on-site. Storage licenses are generally issued site-specific considering specific dual purpose casks (DPC) and their inventories and they are generally limited to 40 years so far. But the need for extending the interim storage period in the future has become obvious. Even though, this may not be an issue to be solved already today questions about additional safety demonstrations will arise as soon as licenses need to be extended. Certainly, these questions will ask for reliable data about the long term performance and safety of structures, systems, and components, e. g. the long term performance of cask components and materials like bolted closure systems including metal seals, or fuel rod behaviour concerning cladding materials under stress and temperature conditions. In case of dual purpose casks for storage and transportation this includes aspects on how to demonstrate transportability during or after several decades of interim storage. Long term investigations often require plenty of time and therefore need to be initiated timely.
Visualization in the Age of Computerization

Field: Computer Science (Physical Sciences)

Digitalization and computerization are now pervasive in science. This has deep consequences for our understanding of scientific knowledge and of the scientific process, and challenges longstanding assumptions and traditional frameworks of thinking of scientific knowledge. Digital media and computational processes challenge our conception of the way in which perception and cognition work in science, of the objectivity of science, and the nature of scientific objects. They bring about new relationships between science, art and other visual media, and new ways of practicing science and organizing
Antileukemic Activity of Ypn-005, a CDK7 Inhibitor, Inducing Apoptosis through c-MYC and FLT3 Suppression in Acute Myeloid Leukemia

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Background Acute myeloid leukemia (AML) is an aggressive blood cancer with a high rate of relapse associated with adverse survival outcomes, especially in elderly patients. An aberrant expression of cyclin-dependent kinase 7 (CDK7) is associated with poor outcomes and CDK7 inhibition has showed antitumor activities in various cancers. In this study, we explored the potential efficacy of YPN-005, a highly selective CDK7 inhibitor, and evaluated a possible mechanism of the antileukemic effect of YPN-005 in vitro, in vivo, and ex vivo AML models. Methods We investigated the efficacy of YPN-005 in AML cell lines, xenograft mouse model, and primary AML cells. The anti-proliferative effect of YPN-005 was measured by cell viability assay using CellTiter-Glo assay, and the apoptotic level was evaluated using Annexin V/PI staining. The phosphorylation of RNA polymerase II, c-MYC, MCL1, and phosphorylated FLT3/STAT5 protein expression was measured using an immunoblotting assay. To reveal the anti-leukemic effect of YPN-005 on AML cells in vivo, we observed tumor load using the IVIS spectrum in vivo imaging system (PerkinElmer) in an orthotopic mouse model using pGFP-transduced MOLM-13 cell line. Results YPN-005 effectively inhibited the proliferation of AML cells by inducing apoptosis and reducing phosphorylation of RNA polymerase II. The c-MYC protein expression decreased with the treatment of YPN-005 (Figure 1.), and the effect of YPN-005 was negatively correlated with c-myc expression. YPN-005 also showed antileukemic activities in primary AML cells, especially those harboring FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) mutation and in in vivo mouse model (Figure 2.). Phosphorylated FLT3/STAT5 was decreased and FLT3/STAT5 was downregulated with YPN-005 treatment. Conclusion In conclusion, our data suggest that YPN-005, a CDK7 inhibitor has a potential role in treating AML by inducing apoptosis and suppressing c-MYC and FLT3/STAT5. The antileukemic property of YPN-005 needs to be further evaluated in FLT3-mutated AML. Figure 1View largeDownload PPTFigure 1View largeDownload PPT Close modal