jimnoneill/paper-to-field-training huggingface dataset:
Discourse About the Government’s Political Goal to Move the Capital of Indonesia

Field: Social Sciences (Social Sciences)

The relocation of the Indonesian capital, which was announced by President Joko Widodo, was certainly no longer a rumour. Indonesia is preparing to build facilities and infrastructure in Borneo as the new capital of Indonesia. The relocation of Indonesia's capital from Jakarta is to become a national medium-term development from 2020 to 2024.
This study aims to find out what political discourse the government wants to achieve in moving the Indonesian capital. In this research, the method used is the analysis of van Dijk's critical discourse in Kompas.com news in August 2019. Based on the results that have been analysed, it is found that the political objectives of the government in moving the new capital from Java to Borneo are motivated by economic equality, the concept of smart cities, geographical location, and efforts to transfer problems from Java to Borneo. Authors conclude that the discourse of moving the capital of Indonesia only sells artificial dreams to the public. The cost of moving the capital to Borneo requires a hefty fee. Moreover, Indonesia's current financial condition is still not a surplus or deficit.
Knowledge regarding hepatitis among students of a selected government school of Trivandrum district, Kerala

Field: Health Professions (Health Sciences)

Background: Hepatitis is inflammation of the liver which is often self-limiting, rarely leading to progressive scarring or hepatocellular carcinoma in case of chronic hepatitis. The objective of this study was to assess the knowledge regarding hepatitis among high school students of a selected government school of Trivandrum district.Methods: A cross sectional study was carried out among high school students of a selected girls only government school of Trivandrum district during October to November 2017. Permission was obtained from Institute Ethics Committee (IEC) for the study. Data was entered in MS Excel and analyzed using SPSS. Knowledge score was calculated and categorized as follows. 0 to 5– poor knowledge, 6 to 11– average knowledge, 12 to 16– very good knowledge, 17 to 21– excellent knowledge.Results: A total of 293 students participated in our study. Majority of the students had very good knowledge regarding hepatitis i.e. 64%, 10% had average knowledge, while 19% had poor knowledge. Only 7% had excellent knowledge. The mean knowledge score was 13.7 (C.I 13.44 -14.02).Conclusions: Overall, the knowledge regarding hepatitis among students was very good.
Data from FDA Approval Summary: Tisagenlecleucel for Treatment of Patients with Relapsed or Refractory B-cell Precursor Acute Lymphoblastic Leukemia

Field: Medicine (Health Sciences)

<div>Abstract<p>Tisagenlecleucel (Kymriah; Novartis Pharmaceuticals) is a CD19-directed genetically modified autologous T-cell immunotherapy. On August 30, 2017, the FDA approved tisagenlecleucel for treatment of patients up to 25 years of age with B-cell precursor acute lymphoblastic leukemia (ALL) that is refractory in second or later relapse. Approval was based on the complete remission (CR) rate, durability of CR, and minimal residual disease (MRD) <0.01% in a cohort of 63 children and young adults with relapsed or refractory ALL treated on a single-arm trial (CCTL019B2202). Treatment consisted of fludarabine and cyclophosphamide followed 2 to 14 days later by a single dose of tisagenlecleucel. The CR rate was 63% (95% confidence interval, 50%–75%), and all CRs had MRD <0.01%. With a median follow-up of 4.8 months, the median duration of response was not reached. Cytokine release syndrome (79%) and neurologic events (65%) were serious toxicities reported in the trial. With implementation of a Risk Evaluation and Mitigation Strategy, the benefit–risk profile was considered acceptable for this patient population with such resistant ALL. A study of safety with 15 years of follow-up is required as a condition of the approval.</p><p>See related commentary by Geyer, p. 1133</p></div>
Opacity Pulse Propagation Measurement and Thermometry in the Evaluation of Carotid Occlusive Vascular Disease: Correlations With Angiography

Field: Medicine (Health Sciences)

A correlative study of four-vessel angiography with measurements of opacity pulse propagation times and skin temperatures over the medial supraorbital areas of the forehead was carried out in 46 patients. Differences in propagation times of greater than 12 milliseconds and/or in thermometric measurements of 1 °F or more were always associated with angiographically demonstrable carotid occlusive disease. In patients with positive angiographical findings, prolongation of pulse propagation time was associated with lower skin temperature when the latter occurred. Test results indicated abnormality in six of seven patients with bilateral carotid occlusive disease. By these methods, unilateral occlusive lesions of 30% to 50% of the vascular lumen were detected in three of five instances where such lesions occurred; occlusive lesions greater than this degree were detected in 15 of 18 patients. The tests identified as "normal" 18 of 23 patients whose four-vessel angiograms were either totally unremarkable or showed lesions compromising less than 30% of the carotid lumen. Combination of these screening tests is more useful than either test employed alone and may be helpful in clinical evaluation of patients with cerebrovascular disease.
Gas identification in electronic nose by using similarity measure between latency patterns

Field: Computer Science (Physical Sciences)

Recently, implementation friendly bio-inspired coding schemes have been developed for an electronic nose system to recognise different gases. In these schemes, a logarithmic timedomain encoding technique is used to covert the response vector of the sensor array in an electronic nose into a latency pattern. These schemes assume a unique temporal sequence of latencies, referred to as a rank order, for each target gas. However, poor repeatability and sensor drift limit the performance of these schemes. In this paper, we use angular separation between the latency patterns of the sensor array for gas identification. An electronic nose system containing an array of commercially available gas sensors and a radio frequency module is developed and characterized in the laboratory environment with four gases. Experimental data is used to compare the performance of our coding scheme with existing bio-inspired coding schemes and commonly used pattern recognition algorithms.
Indigenizing visualized knowledge: translating Western science illustrations in China, 1870–1910

Field: Arts and Humanities (Social Sciences)

This article discusses how the translation of science illustrations operated interculturally in late nineteenth- and early twentieth-century China. I examine three categories of translated images: those with transformation in core information, those with alterations in peripheral information and those without any changes. In order to understand the differences between Western images and their Chinese translations, I analyze the nature of science illustrations, the problem of “visual literacy” and the goals of the translators involved. I contend that illustrators' personal understanding of science and artistic training played a significant role in adapting Western images to Chinese visual conventions and thus potentially aiding Chinese readers' access to Western science. Examining the different divisions of labor required by different printing techniques, I argue that even in the face of electrotypography's challenge to human intervention, translators still made some aesthetic choices and balanced them with practical needs.
An Attention-Based LSTM-ELECTRE Model for Intelligent and Proactive Load Balancing in Real-Time Fog Computing Environments

Field: Computer Science (Physical Sciences)

Load balancing between nodes is a fundamental challenge for fog computing environments, which are associated with dynamic Internet of Things (IoT) applications that require real-time responses. From this perspective, this study proposes an advanced hybrid model that combines the deep learning capabilities of LSTM networks with an attention mechanism to focus on the most significant time segments of the data series when predicting the upcoming load. Then, a multi-criteria decision-making algorithm follows, the ELECTRE algorithm, allowing optimal load prediction and intelligent task distribution across nodes to achieve fog computing stability. The proposed model bridges the gap in previous studies that do not consider task distribution mechanisms across nodes, load balancing prediction, and the nonlinear nature of the data. The proposed model was tested on two Mendeley datasets and a synthetic dataset to evaluate its generalization performance. The proposed model demonstrated excellent performance in terms of accuracy (R² up to 0.99), low prediction error (MAE = 0.0085), effective load balance, and 100% task completion rate. The results obtained, compared to other approaches, confirm that the proposed method demonstrates high accuracy, is generalizable, and can be integrated with other models, such as fault prediction systems. This makes it a promising framework for more stable and reliable fuzzy environments within the current timeframe.
STEM CELL PLASTICITY: REGENERATION OF FUNCTIONAL MYOCARDIUM FROM BONE MARROW STEM CELLS (BMSC).

Field: Medicine (Health Sciences)

O417 Aims: Bone marrow stem cells (BMSC) have been demonstrated to have the capacity to repair damaged neural, cardiac, and skeletal tissue under selected conditions. As such, BMSC offer great promise for regenerative medicine. However, functional assessment of outcomes has been limited, and it remains controversial whether significant functional repair can be achieved. Methods: In the present studies we evaluated whether treatment of mice with hematopoietic growth factors to mobilize BMSC would enhance functional repair after myocardial infarction (MI). Three groups of mice underwent a 30 minute coronary artery occlusion followed by reperfusion. Mice were treated with G-CSF plus Flt3 ligand (FL) (★–★; n = 16); G-CSF plus SCF (SYMBOL; n = 18) and compared to vehicle-treated controls (⊠–⊠; n = 17). Left ventricular function was assessed at baseline, 48 hours after MI, and at 35 days.SYMBOLResults: Strikingly, there was a significant (P <0.05) improvement in function in the growth factor-treated groups as early as 35 days, with the most significant improvement in the group receiving FL + G-CSF. Importantly, this correlated directly with the absolute number of mobilized HSC and graft facilitating cells (FC). The most profound increase occurred with the combination of G-CSF and FL (★–★). To confirm that this functional outcome was due to BMSC, chimeras were prepared using EGFP+ BMC and enrolled in the protocol. At 35 days the hearts were retrieved and examined for EGFP+/troponin+ cardiomyocytes. There were no EGFP+ cardiomyocytes in vehicle-treated controls, while there was a significant number of EGFP+/troponin+ cardiomyocytes in the growth factor-treated chimeras, confirming that BMSC contributed directly to the newly generated cardiac tissue. Studies are underway to determine the relative contribution of each of these cellular subpopulations on functional outcome in stem cell repair. Conclusions: Optimization of function and composition of the SC product could offer significant advantage to enhance myocardial repair following MI and may hold great therapeutic potential in the clinic.Figure
Perspectives of Mesenchymal Stem Cell-Based Neuroregeneration

Field: Neuroscience (Life Sciences)

Stem cell-based therapy seems to be a promising strategy to treat neurodegenerative diseases, in particular those that are fatal and difficult to treat. However, the sources of stem cells are required to comply with the requirement of availability and expanding in culture, to overcome ethical objections and concerns of graft rejection. Mesenchymal stem cells (MSCs) are population of adult stem cells that fulfill all these criteria. These cells are able to differentiate into osteoblasts, chondrocytes and adipocytes as well as cardiomyocytes, hepatocytes, endothelial and pancreatic cells. The most recent studies have been focused on the neurogenic potential of mesenchymal stem cells expressed by their ability to differentiate into neural and glial cell types. The article focuses on current approaches to the mesenchymal stem cell-based neuroregeneration and their perspectives. The anti-inflammatory action of MSCs and their potential effects on neuroprotection and neuroregeneration has been described in respect to the central nervous system (CNS) disorders. Some representative clinical and experimental trials using MSCs in CNS therapies have been specified.
ChemInform Abstract: Aluminum‐Mediated One‐Pot Conversion of α‐Amino Acid Esters to threo‐2‐Amino Alcohols with High Diastereoselectivity.

Field: Chemistry (Physical Sciences)

Abstract The N‐Cbz‐protected (S)‐amino acid esters (I) are reduced with diisobutylaluminum hydride and subsequently treated with the Grignard reagents (II) to give diastereomeric mixtures of the 2‐amino alcohols (III) with the predominance of the threo‐isomers.
Safety of Simultaneous Vaccination With Adjuvanted Zoster Vaccine and Adjuvanted Influenza Vaccine

Field: Medicine (Health Sciences)

Importance Quadrivalent adjuvanted inactivated influenza vaccine (aIIV4) and adjuvanted recombinant zoster vaccine (RZV) contain novel adjuvants. Data are limited on the comparative safety, reactogenicity, and health-related quality of life (HRQOL) effects of the simultaneous administration of these vaccines. Objective To compare the safety and reactogenicity after simultaneous doses of RZV and aIIV4 administration (opposite arms) with simultaneous doses of RZV with quadrivalent high-dose inactivated influenza vaccine [HD-IIV4]). Design, Setting, and Participants This randomized blinded clinical trial was conducted during the 2021-2022 and 2022-2023 influenza seasons at 2 centers in the US among community-dwelling adults aged 65 years or older. Analysis was performed on an intention-to-treat basis. Intervention Simultaneous intramuscular administration of RZV dose 1 and aIIV4 or HD-IIV4 in opposite arms after age stratification (65-69 and ≥70 years) and randomization. Main Outcomes and Measures The primary outcome was the proportions of participants with 1 or more severe solicited reactions during days 1 to 8, using a noninferiority test (10% noninferiority margin). Additional measures included serious adverse events and adverse events of clinical interest during days 1 to 43 of the study period. Results A total of 267 adults (median age, 71 years [range, 65-92 years]; 137 men [51.3%]) were randomized; 130 received simultaneous RZV and aIIV4, and 137 received simultaneous RZV and HD-IIV4. The proportion of patients reporting 1 or more severe reactions after simultaneous administration of RZV and aIIV4 (15 of 115 [11.5%]) was noninferior compared with simultaneous RZV and HD-IIV4 (17 of 119 [12.5%]) (absolute difference, −1.0% [95% CI, −8.9% to 7.1%]). There were no significant differences in the number of serious adverse events or adverse events of clinical interest between the groups. Conclusions and Relevance In this clinical trial of simultaneous doses of RZV and aIIV4 compared with simultaneous doses of RZV and HD-IIV4, overall safety findings were similar between groups. From a safety standpoint, this study supports the simultaneous administration of RZV and aIIV4 among older adults. Trial Registration ClinicalTrials.gov Identifier: NCT05007041
Expert Psychiatric Evidence in Sexual Misconduct Cases Before State Medical Boards

Field: Social Sciences (Social Sciences)

The growing problem of physician sexual misconduct has captured the attention not only of the medical and legal communities, but of the public as well. State medical boards, administrative agencies with generous rules of evidence and varying levels of expertise, face the difficult task of responding to patients’ allegations of physician sexual abuse. This Article, based in large part on the author's survey of current state medical board practice, reveals an increasing reliance on expert psychiatric testimony to explain the behavior of complainants and accused physicians. Drawing analogies from the use of psychiatric evidence in child sexual abuse cases, the author examines the factors that boards must consider in determining the admissibility of expert testimony in physician sexual misconduct cases, and calls upon states to establish clear evidentiary rules to govern the use of such testimony in administrative hearings.
Methodology for the in situ testing of the moisture content of brick walls: an example of application

Field: Engineering (Physical Sciences)

Abstract The article presents original methodology of testing the moisture content of brick walls in buildings. It was developed on the basis of own experience acquired during testing the moisture content in many excessively wet buildings erected in various historical periods. The tests were conducted using different methods, including non-destructive methods. To emphasize the importance of the problem, an overview of the methodology was preceded by a brief presentation of the causes and negative effects of excessive moisture and salinity in brick walls. In addition, the article is illustrated with an example of the effects of moisture content tests carried out according to the developed methodology on a facility from the fourteenth century. According to the author, knowledge of the presented methodology, and its application, should contribute to both the improvement of the quality of conducted research and the credibility of the obtained results.
Blunted serum 25(OH)D response to vitamin D3supplementation in children with autism

Field: Medicine (Health Sciences)

Introduction: Data suggest a potential role for vitamin D in autism spectrum disorder (ASD) prevention and treatment. It is likely that the serum response to vitamin D supplementation contributes to its effectiveness. Multiple factors affect serum vitamin D 25(OH)D response to supplementation. Methods: We conducted post-hoc analysis of two double-blind, randomized, placebo-controlled trials (RCT) of vitamin D3 supplementation, one RCT involving children with ASD and another involving children with asthma. Both trials were conducted in the same geographic location (Dublin, Ireland, 53°N), conducted over Winter season and utilized the same vitamin D3 dose (2000 IU/day). Results: We included 18 children with ASD and 17 children with asthma. There was no significant difference in 25(OH)D or age at baseline, however, BMI was significantly lower in ASD (P = 0.03). Compliance with vitamin D supplementation was high in both trials. Despite a significantly longer intervention period (20w vs. 15w; P < 0.0001), ASD children had a significantly lower absolute increase (+26 vs. +45 nmol/l) in 25(OH)D (P = 0.04). Conclusions: Despite similar demographics, children with ASD had a lower increase in 25(OH)D levels with supplementation. Potential mechanisms include altered absorption/metabolism as well as well genetic factors. Clinical and research work relating to vitamin D is ASD should measure 25(OHO)D response to supplementation to assess therapeutic doses.
Austria, Finland and Sweden inside the European Union: employeerelations issues

Field: Social Sciences (Social Sciences)

An introductory article to a monograph on HRM philosophies and practices in the three new states acceding to the EU in 1995 Austria, Finland and Sweden. Highlights distinctive features of the employment systems and labour market practices in each country, and outlines the kinds of social issue which may be brought more into prominence within the EU as a result of the membership of the three countries.
To Observe the Hemodynamical Changes of Ophthalmical Arterial in Cerebral Ischemia using Color Doppler Flow Imaging

Field: Medicine (Health Sciences)

Objective to study the changble character of the ophthalmie arterial hemodynamics In cerebral Ischemia. Methods By means of American GELogiq7 color untrasound equipment and choose 50 patients that were diagnosed to one side cerebral ischemia by measurement TCD, then adopt the way of one side comparing with self-body’s another side and make use of CDFI, the parameter of ophthalmic arterial hemodynamics was abserved. Results It was found that the blood flow of ophthomic artery accord with the character of encephalic arterial hemndynamics and the wave is low resistant type. The corresponding change of the blood flow of the ophthalmic arteries takes place when the internal carotid artery stricture lead to acute cerebral ischemia. The Vmean, Vmax, RI, PI of the ophthalmia artery showed significant reduce, but the change of Vmin was no difference. Conclusion According to the changble conditions of ophthalmic artery, the change of the cerebral hemodynamics can be reflected indirectly, which can be used as a new diagnosed method to judge cerebral ischemia.
CLASSIFICATION OF TANAFFUS (RESPIRATION) WITH SPECIAL REFERENCE TO UNANI MEDICINE: A REVIEW

Field: Medicine (Health Sciences)

Breathing or respiration has been essential in human life since ancient times. Philosophers and physicians of ancient times such as Hippocrates, Galen, and others had already written about breathing in literature. These antiquated viewpoints established the foundation for contemporary respiratory physiology and medicine. The Hippocratic literature established the importance of breath in maintaining the body's humour balance, whereas Galen elaborates on the anatomical and functional elements of respiration. Literature related to respiration is surveyed from various Unani classical books and their translations, commentaries, previous dissertations, journals, proceedings, etc. Hippocrates and Ibne Sina mentioned ten and seventeen types of respiration respectively. Ibne Sina also explained five special types of respirations. This research paper aims to explore and analyse the understanding and significance of respiration in the Unani system of medicine. And also provides a comprehensive overview of how ancient philosophers understood respiration.
Mediators' Facilitative Versus Controlling Argument Strategies and Tactics: A Qualitative Analysis Using the Conversational Argument Coding System

Field: Social Sciences (Social Sciences)

This study examined how utilization of the Conversational Argument Coding Scheme (CACS) demonstrates mediators' use of argument behavior to facilitate or control the manner in which mediation parties argued their positions. Data were collected from a community mediation program located in the southwestern United States. Forty mediation sessions, each having a single mediator, were videotaped and transcribed. Results revealed eight mediator argument tactics that reflect a facilitative strategy and three argument tactics that represent a controlling strategy. Discussion focuses on how the CACS can demonstrate ways in which mediators promote disputants' idea development or, in some cases, impede participants' use of argument to make known their ideas.
An Application of Geostatistics and Fractal Geometry for Reservoir Characterization

Field: Earth and Planetary Sciences (Physical Sciences)

Summary This study presents an application of geostatistics and fractal geometry concepts for 2D characterization of rock properties (k and ϕ) in a dolomitic, layered-cake reservoir. The results indicate that lack of closely spaced data yield effectively random distributions of properties. Further, incorporation of geology reduces uncertainties in fractal interpolation of wellbore properties.