jimnoneill/paper-to-field-training huggingface dataset:
Chemical-Assisted Bonding of Thermoplastics/Elastomer for Fabricating Microfluidic Valves

Field: Engineering (Physical Sciences)

Thermoplastics such as cyclic olefin copolymer (COC) and polymethylmethacrylate (PMMA) have been increasingly used in fabricating microfluidic devices. However, the state-of-the-art microvalve technology is a polydimethylsiloxane (PDMS)-based three-layer structure. In order to integrate such a valve with a thermoplastics-based microfluidic device, a bonding method for thermoplastics/PDMS must be developed. We report here a method to bond COC with PDMS through surface activation by corona discharge, surface modification using 3-(trimethoxysilyl)propyl methacrylate (TMSPMA), and thermal annealing. The method is also applicable to PMMA. The bonding strength between thermoplastics and PDMS was represented by the peeling force, which was measured using a method established by the International Organization for Standardization (ISO). The bonding strength measurement offered an objective and quantitative indicator for protocol optimization, as well as comparison with other PDMS-associated bonding methods. Using optimized bonding conditions, two valve arrays were fabricated in a COC/PDMS/COC device and cyclic operations of valve closing/opening were successfully demonstrated. The valve-containing devices withstood 100 psi (∼689 KPa) without delamination. Further, we integrated such valve arrays in a device for protein separation and demonstrated isoelectric focusing in the presence of valves.
The phylogenetic relationships between actinolepids (Placodermi: Arthrodira) and other arthrodires (phlyctaeniids and brachythoracids)

Field: Agricultural and Biological Sciences (Life Sciences)

The phylogenetic relationships between actinolepids (Placodermi, Arthrodira) and other arthrodires (Phlyctaenii and Brachythoraci) are re-evaluated in connection with a study in progress on some Podolian and Spitsbergen actinolepid material. The species Kujdanowiaspis podolica (Brotzen, 1934) is briefly redescribed, and its characters discussed in relation to a recent cladistic analysis of the actinolepids. An enlarged phylogenetic analysis using a data matrix of 55 characters for 31 taxa reveals that the actinolepids may be a paraphyletic group; their taxonomic and nomenclatural status is briefly discussed. Within the actinolepids, the genus Kujdanowiaspis does not have the basal position proposed by previous authors. A proposed new phylogeny shows Wuttagoonaspis as the sister group to all other arthrodires, and the Phyllolepida as the sister group to the Phlyctaenioidei (Phlyctaenii plus Brachythoraci).
Emigration of Mathematicians and Transmission of Mathematics: Historical Lessons and Consequences of the Third Reich

Field: Arts and Humanities (Social Sciences)

This conference provided a focused venue to explore the intellectual migration of mathematicians and mathematics spurred by the Nazis and still influential today. The week of talks and discussions (both formal and informal) created a rich opportunity for the cross-fertilization of ideas among almost 50 mathematicians, historians of mathematics, general historians, and curators.
Carbonylation induced by antibiotic and pesticide residues on casein increases its IgE binding and allergenicity

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

This work aimed to evaluate the effect of carbonylation induced by tetracyclines, β-lactams, fluoroquinolones, and pyrethroids in caseins of bovine origin on their immunoreactivity and allergenicity. Using a spectrophotometric method, ELISA, dot-blot, and an IgE-mediated milk allergy mouse model, we confirmed that antibiotics and pesticides at their maximum residue limit, promoted the in vitro carbonylation of caseins (among 5.0 ± 0.01 and 67.5 ± 0.70 nmol of carbonyl/mg of protein); furthermore, carbonylations greater than 19 nmol significantly increase the in vitro IgE immunoreactivity of caseins (average OD among 0.63-1.50) regarding the negative control (average OD: 0.56). On the other hand, sensitized mice exposed to oxidized caseins showed increased clinical scores (2-5), positive skin tests, and footpad swelling (0.28-0.59 mm) compared to the negative control (1-2; negative skin tests; 0.1 mm, respectively), denoting increased allergenicity. These results suggest that casein carbonylation increases their IgE immunoreactivity and allergenicity, a fact that could be explained by the resistance to the digestion promoted by carbonylation and by conformational changes in the random coil casein structure, which can expose cryptic epitopes or neoepitopes.
Water is life and death: Symbolic representation in all customs and rituals in India

Field: Social Sciences (Social Sciences)

Abstract For the Koch, Koch Rajbongshi, and Rajbanshi people of India, water is central to their culture. They share river music and ancestry. They lost their language in 1931 and split into three or more clans due to flood relocation. They also introduced food, the river, the sun, the moon, the bamboo tree, and cactus plant worship to the highlands. The parent group was identified as tribal in the 1931 census. Still, the Indian government could not grant Koch, Koch Rajbongshi, and Rajbanshi “scheduled tribe” status for Assam and conserve their culture, traditions, and language. Indian scientists are trying to solve Assam's centuries‐old flood issues, which are worsening. The new Indian water framework must treat “water access” and “value of water resources” as “essentially good” and “human rights” issues. India must review its Assam flood failures and compensate locals. Assam needs political, social, economic, and administrative procedures to develop and manage water resources and offer services at different societal levels.
Implementation of Al-Miftah Lil â€˜Ulum Program in Learning to Read Kitab Kuning at Pondok Pesantren Nurul Huda

Field: Arts and Humanities (Social Sciences)

The al-Miftah lil 'Ulum program is a special program or selected group at pondok pesantren Nurul Huda, Pakamban Laok, Pragaan, Sumenep. The purpose of the al miftah program can improve the ability to read kitab kuning of students. This type of research is a qualitative case study whose data collection process is by observation, documentation, and interviews. While the data analysis is interactive analysis by reducing the data, displaying and verifying it then making conclusions. In this study using descriptive qualitative method. Based on the results of observations of teaching teachers and students, it is known that by participating in the al-Miftah lil 'Ulum Program at pondok pesantren Nurul Huda, the ability to read kitab kuning of students increases. From the results of the study, it was concluded that the al-Miftah lil 'Ulum Program was effective and efficient to be implemented at pondok pesantren Nurul Huda, Pakamban Laok, Pragaan, Sumenep in learning kitab kuning.
Spectrum of activity of levofloxacin against nontuberculous mycobacteria and its activity against the Mycobacterium avium complex in combination with ethambutol, rifampin, roxithromycin, amikacin, and clofazimine

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The spectrum of activity of levofloxacin was initially determined against 29 strains belonging to 16 species of atypical mycobacteria by measuring radiometric MICs. Levofloxacin MICs were 1 to 2 dilutions lower compared with those obtained for ofloxacin and 8 to 64 dilutions lower compared with those obtained for its D-isomer. Levofloxacin MICs were below its peak level in serum (5.5 micrograms/ml following administration of a single oral dose of 350 mg) for 25 of 29 isolates tested. It possessed MICs below its peak level in serum for M. scrofulaceum, M. szulgai, M. malmoense, M. xenopi, M. marinum, M. kansasii, M. chelonei, M. abcessus, M. fortuitum, and M. peregrinum. Regarding the M. avium complex, the MICs of levofloxacin for 11 clinical isolates (7 from human immunodeficiency virus-positive patients and 4 from human immunodeficiency virus-negative patients) were 1 to 2 dilutions lower than those of ofloxacin. Among 20 isolates belonging to 12 pathogenic mycobacterial species, the MBC/MIC ratios varied from 1 to 4 for levofloxacin and 2 to 4 for ofloxacin. When drug combinations were screened by using the radiometric x/y quotient methodology against five M. avium complex isolates, levofloxacin activity against all five isolates was enhanced by ethambutol and activity against three isolates was enhanced by clofazimine. Screening of three-drug combinations showed that the combination levofloxacin-ethambutol with a third potential anti-M. avium drug (rifampin, roxithromycin, amikacin, or clofazimine) resulted in enhanced activity for all 20 drug combinations screened.
COMPOSITION AND PROPERTIES OF CAPROLACTAM OLIGOMERS OBTAINED FROM EXTRACTION WATER DIRECTED TO REGENERATION

Field: Chemical Engineering (Physical Sciences)

The analysis results of the extraction water forming at various steps of the solutions concentration in a process of its regeneration at the production of PA-6 at JSC "KuibyshevAzot" allowed to recommend such compositions of reaction mixtures, directed to polymerization, the content in which of OL corresponds to their equilibrium values in a polymer and to reduce the temperature of carrying out of concentrating the extraction water using an environmentally safe heat carrier that is superheated steam.
Materiality of evidence-based policy making for child and adolescent psychiatry in Japan

Field: Social Sciences (Social Sciences)

The Japanese government established the Children and Family Agency in April 2023 and is trying to promote evidence-based policymaking (EBPM). However, the current state of child and adolescent psychiatry in Japan demonstrated some difficulties. School refusal and suicide problems are increasing after the coronavirus disease-2019 (COVID-19) pandemic. These issues need to be addressed, thereby warranting various policies to be developed and implemented. Increasing the number of inpatient medical institutions and establishing a community-based data accumulation system that enables data and knowledge sharing among professionals is essential to improve child and adolescent psychiatric care. Furthermore, EBPM is needed to effectively develop a policy, and specialized experts are necessary to organize data and critically review evidence.
Pentaquark states in a diquark-triquark model

Field: Physics and Astronomy (Physical Sciences)

The diquark-triquark model is used to explain charmonium-pentaquark states, i.e., $P_c(4380)$ and $P_c(4450)$, which were observed recently by the LHCb collaboration. For the first time, we investigate the properties of the color attractive configuration of a triquark and we define a nonlocal light cone distribution amplitude for pentaquark states, where both diquark and triquark are not pointlike, but they have nonzero size. We establish an effective diquark-triquark Hamiltonian based on spin-orbital interaction. According to the Hamiltonian, we show that the minimum mass splitting between $\frac{5}{2}^+$ and $\frac{3}{2}^-$ is around $100$~MeV, which may naturally solve the challenging problem of small mass splitting between $P_c(4450)$ and $P_c(4380)$. This helps to understand the peculiarities of $P_c(4380)$ with a broad decay width whereas $P_c(4450)$ has a narrow decay width. Based on the diquark-triquark model, we predict more pentaquark states, which will hopefully be measured in future experiments.
Penegakan Hukum Terhadap Tindak Pidana Penjualan Smartphone Ilegal Dalam Perspektif Undang-Undang Nomor 8 Tahun 1999 Tentang Perlindungan Konsumen

Field: Social Sciences (Social Sciences)

The aim of writing this scientific work is of course to determine law enforcement regarding criminal acts of illegal smartphone sales in the perspective of Law Number 8 of 1999 concerning Consumer Protection with data collection techniques using normative juridical methods and library research. The research results show that the distribution of illegal smartphones can be overcome by implementing Article 62 Paragraph (1) in conjunction with Article 8 Paragraph (1) letter a of Law no. 8 of 1999 relating to consumer protection with the threat of a maximum prison sentence of five years and a maximum fine of 2 billion Rupiah as well as Article 52 Juncto Article 32 Paragraph (1) of Law no. 36 of 1999 concerning Telecommunications with the threat of a maximum prison sentence of 1 year or a maximum fine of one hundred million rupiah.
A comparative analysis of the performance of initial public offering shares in the medium term as compared to shares of mature listed companies.

Field: Economics, Econometrics and Finance (Social Sciences)

This project consist of two modules. The first part involves an empirical study to compare the returns of investment in IPOs with that of mature companies listed both on the Main Board and SESDAQ of the Stock Exchange of Singapore. The second section attempts to investigate the possible factors such as gearing, market capitalization and Price-Earning ratios, that may contribute to the phenomenon displayed from the result of the first study. The scope of this paper comprises of short-term returns and medium-term returns of investments in the stocks. In addition, comparison of short-term returns with the medium-term returns of the IPOs are also made. All Singapore-dollar based IPOs from 2nd January 1990 to 31st December 1995 are the object of this paper.
An Ethic of Care: Interrogating the Need for Care in the Archives

Field: Arts and Humanities (Social Sciences)

Using a mixture of personal experience and frameworks presented by Caswell and Cifor (2016), this essay explores the tangible ways that archival spaces can and should account for the affective responses of their user groups. Drawing on a case study at Algoma University, care work is demonstrated to be an imperative element for just, engaged, and enriched archival service.
Posterior Tibial Artery Perforator V-Y Advancement Flap for Small–Medium Size Lower Limb Defects

Field: Medicine (Health Sciences)

Background: The posterior tibial artery perforator flap has been described as a good option for small to moderate lower extremity defects with consistent anatomy and caliber. Different geometrical designs are found in the literature for posterior tibial artery perforator flaps and are mostly executed as propeller, peninsular, and island flaps. Upon literature review, V-Y advancement flaps were not commonly used, despite the clear design, persistent anatomy, and straight execution. Our aim was to report our case series to present the validity of such design and the success of reconstruction. Method: Over 1 year, three cases were reconstructed successfully with posterior tibial artery perforator flaps with V-Y advancement design. Clinical evaluation was done for all patients as well as follow-up in the outpatient clinic until complete healing of the wounds was achieved. Multiple modifications were done intraoperatively to enhance flap reach and minimize the complications, including designing V-Y advancement flaps larger than the defect, careful perforator dissection, and finally, strict postoperative course. Results: All three cases healed completely with no complications. The average follow-up time in the clinic was 3 months. Conclusions: Posterior tibial artery perforator flap with V-Y advancement design is a viable option for reconstructing medium sized lower limb defects, but requires careful design and execution. The suggested steps will increase the survival of the flap and reconstruct the defect successfully.
Genetic polymorphism of milk proteins: relationship with milk compositional traits in Indian goat breeds

Field: Agricultural and Biological Sciences (Life Sciences)

M samples of Jakhrana(70) and Sirohi (22) goat breeds, maintained at the Central Institute for Research on Goats, Makhdoom, Mathura, Uttar Pradesh, India, were analyzed to study the genetic polymorphisms of milk proteins and its effect on milk compositional traits. The genetic variants in milk samples were detected by sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) method. The different milk compositional traits (viz. casein, total protein, fat, total solid, and solid-not-fat content in milk) were estimated by using standard protocol. The electrophoretic pattern revealed that milk sample of both the breeds contained four major casein variants, i.e., αS1casein , αS2 casein , β-Cn, and κ -Cn and two whey proteins i.e., βlactoglobulin and αlactalbumin. Further αS1casein locus showed 2 variants such as A and F with a frequency of 0.843 and 0.157, respectively in Jakhrana goat, whereas three variants of αS1casein viz., A, B and F, were observed in Sirohi goat, having the allelic frequencies of 0.636, 0.296 and 0.068, respectively. No polymorphic pattern was observed at αS2-, β-, κ-casein locus and β-lactoglobulin whey protein locus in Jakhrana breed. However, the electrophoretic pattern of α -lactalbumin variant also showed two allelic forms i.e., A and B with frequencies of 0.97 and 0.03, respectively in Jakhrana breed. In Sirohi breed, two variants viz. A and B with gene frequencies 0.77 and 0.23 respectively were observed at αS2casein locus, but no polymorphism exists at β-casein, κ-casein, β-lactoglobulin and α -lactalbumin locus. The study also revealed that milk protein variants had no significant (P>0.05) effect on all milk compositional traits in both Jakhrana and Sirohi breeds.
Knowledge domain coupling, digital transformation and R&D team innovation performance

Field: Business, Management and Accounting (Social Sciences)

Purpose Based on theories such as knowledge management and resource base, this paper explores the effect of knowledge domain coupling on R&D team innovation performance under the perspective of technological innovation networks as well as the mediating role of digital transformation, and further validates the moderating role played by organizational innovation climate and environmental turbulence. Design/methodology/approach Taking the data of 239 Chinese enterprises with high R&D intensity and strong innovation ability as samples, SPSS and AMOS are used for empirical testing. Findings The findings suggest that knowledge domain coupling and its decomposition variables (complementary knowledge coupling and iterative knowledge coupling) have a significant positive effect on R&D team innovation performance, digital transformation partially mediates the relationship between knowledge domain coupling and R&D team innovation performance, and that there is a positive moderating effect of organizational innovation climate and environmental turbulence in the influence path. Originality/value The study has enlightening value for innovative enterprises and their R&D teams on how to effectively couple the knowledge, make reasonable use of iterative technologies and promote digital transformation practices to enhance innovation performance.
Raw data for Hancock-Cerutti et. al. "ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling"

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Blot images and tabular data for Hancock-Cerutti et. al. "ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling"
Does Students\’ International Mobility Increase Their Employability?

Field: Economics, Econometrics and Finance (Social Sciences)

During the last 20 years international mobility of Polish students grew significantly. The article addresses the issue of consequences of international mobility for graduates\’ employability. Theoretical literature suggests several channels through which internationalmobilitymay affect graduates\’ attractiveness in the labour market: by accumulation of additional human capital, by signalling high abilities of a job candidate, by increasing search intensity of jobseekers. In fact, simple comparison of employment rates and duration of a post-graduation job search suggest that mobility experience increases employability of higher education graduates. However the results of Cox proportional hazard model with a control for other graduates\’ characteristics reveals a different picture: mobility per se does not impact job search duration but is correlated with graduates\’ characteristics associated with higher abilities. It seems, therefore, that international mobility experience may serve as a screening device and be used by firms for the purpose of recruiting better candidates.
Magical bullets from an indigenous Indian medicinal plant Tinospora cordifolia: An in silico approach for the antidote of SARS-CoV-2

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

World Health Organization declared COVID-19 as a global pandemic. Till now, a diverse array of drugs failed to combat. There is an immense need of novel lead molecules on a urgent basis. Medicinal plants are the reservoir of secondary metabolites. In silico approach has been carried out to dock the ligands (various secondary metabolites from Tinospora cordifolia) to the target (SARS-CoV-2 main protease) and compared its efficacy against standard drugs (Azithromycin, Chloroquine, Hydroxychloroquine, Favipiravir, Remdesivir). In silico molecular docking approach provides insight into the screened molecules that might prove to be an effective inhibitor for SARS-CoV-2. Out of five standard drug molecules, two widely used antiviral drugs (Favipiravir and Remdesivir) are ascribed as the most potent molecules based on their highest docking score in the present study. Columbin, Tinosporide, N-trans-feruloyl-tyramine-diacetate, Amritoside C, Amritoside B, Amritoside A, Tinocordifolin, Palmatoside G, Palmatoside F, and Maslinic acids are other molecules considered to be the key molecules based on their docking score (range between -5.02 to −5.72).
Green Supply Chain Network Design

Field: Decision Sciences (Social Sciences)

This thesis presents an analysis of Elhedhli and Merrick's paper, Green supply chain network design to reduce carbon emissions. Elhedhli and Merrick proposed a supply chain model to find the optimal placement of distribution centres (DCs) while minimizing transportation costs, the fixed cost of opening the DC and carbon emissions costs.They found that considering carbon emissions creates a pull to reduce the vehicle kilometers travelled, and results in a supply chain network with more DCs opened compared to a supply chain network that does not consider carbon emissions.This thesis is an exploration of the model and solution methods proposed by Elhedhli and Merrick. An overview of optimization topics, a description of Lagrangian relaxation and an outline of decomposition methods is included to provide background knowledge for the description of the green supply chain network model, and its solution methods. We use the algorithm suggested by Elhedhli and Merrick to find the optimal solution of three supply chain networks: one considering zero emissions costs, one considering moderate emissions costs and one considering high emissions costs. The results obtained from the three scenarios confirm the results of Elhedhli and Merrick.
Study on Demonstration of Orchards Building in Loess Plateau on Mountain Slope Land

Field: Agricultural and Biological Sciences (Life Sciences)

The productivity of apple, pear,and Chinese date in slopping field were studied in altiplanogully region,first and second hilly subsidiary region in Loess Plateau. The results shown that with the application of the new techniques the fruittrees growth and productivity were increased markedly; the fertility of soil index values were higher 3%～121%, the pure economical income was higher 2.8～7 times; the relative variation, absolut variation and coefficient variation of productivity and production value were lower; the fruittree field took on higher stability and renewal capacity than those of cropland. Those above indicated that sloping field displacing with garden was a important approach of efficient utilization of land resources in Loess Plateau.