jimnoneill/paper-to-field-training huggingface dataset:
Inflammation and Hyperglycemia Mediate Deaf1 Splicing in the Pancreatic Lymph Nodes via Distinct Pathways During Type 1 Diabetes

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Peripheral tolerance is partially controlled by the expression of peripheral tissue antigens (PTAs) in lymph node stromal cells (LNSCs). We previously identified a transcriptional regulator, deformed epidermal autoregulatory factor 1 (Deaf1), that can regulate PTA expression in LNSCs of the pancreatic lymph nodes (PLNs). During the pathogenesis of type 1 diabetes (T1D), Deaf1 is spliced to form the dominant-negative isoform Deaf1-Var1. Here we show that Deaf1-Var1 expression correlates with the severity of disease in NOD mice and is reduced in the PLNs of mice that do not develop hyperglycemia. Inflammation and hyperglycemia independently drive Deaf1 splicing through activation of the splicing factors Srsf10 and Ptbp2, respectively. Inflammation induced by injection of activated splenocytes increased Deaf1-Var1 and Srsf10, but not Ptbp2, in the PLNs of NOD.SCID mice. Hyperglycemia induced by treatment with the insulin receptor agonist S961 increased Deaf1-Var1 and Ptbp2, but not Srsf10, in the PLNs of NOD.B10 and NOD mice. Overexpression of PTBP2 and/or SRSF10 also increased human DEAF1-VAR1 and reduced PTA expression in HEK293T cells. These data suggest that during the progression of T1D, inflammation and hyperglycemia mediate the splicing of DEAF1 and loss of PTA expression in LNSCs by regulating the expression of SRSF10 and PTBP2.
An Econometric Exploration of Indian Saving Behavior

Field: Economics, Econometrics and Finance (Social Sciences)

Abstract The purpose of the study is to throw some light on the saving behavior of urban Indian households. The nature of the effects on saving of income and net worth and their interactions are examined in detail for different socio-economic sub-groups. There is strong evidence that income and net worth significantly influence the level of saving. Contrary to the studies in advanced countries, home-owners had a much lower saving-income ratio than renters although the former had a slightly higher average income. A major reason for this may be the uncommon-ness of amortized mortgages in India, with no contractual commitment to save. Except for age 65 or over, mean income, saving and the saving-income ratio increased with age up to 45 years and thereafter declined. The age group 65 or over had a higher average income and saved the highest proportion of income. This is perhaps due to the prevalence of joint families in India.
A Translation of Vera Gherarducci’s Giorno Unico

Field: Arts and Humanities (Social Sciences)

Italian poet Vera Gherarducci published her second book, Giorno Unico (A Single Day), in 1970. This project consists of translations of 24 of these poems, a translation of the book’s introduction by Pier Paolo Pasolini, and a critical translator’s introduction. The critical introduction positions the work within the context of post-war Italian women’s poetry; explores the legacy of mental health in literature and its ties with diary writing and gender; and discusses specific translation strategies related to these issues. Giorno Unico deals extensively with themes of mental health, focusing on struggles with depression, suicidal thoughts, marital problems, and maternal anxieties. Such topics place the work in conversation with many other post-war women writers in Italy grappling with new conceptions of womanhood and the burgeoning Italian feminist movement. Themes of mental health are also expressed by the poems being written in the form of an intimate diary, though the temporal mapping is complicated by flashback and circular narration. As the title suggests, these poems come to resemble one long, never-ending day, manifesting in the recurrence of words and phrases, frequent mental health metaphors of being trapped inside, and the repetition of monotonous household work. After contextualizing the work’s primary characteristics, I then frame my own translation approach that looks to foreground the presence of mental health and preserve the characteristics of the diary form. This approach was influenced by feminist translation theorists such as Sherry Simon and Barbara Godard who challenge the monolithic nature of both source and target texts, and endorse the recovery of forgotten women writers through translation. In my principal theoretical assertion, I push against Lawrence Venuti’s discussion of the inherent violence enacted in translation, and conceive of what I term a non-lobotomizing translation approach to Giorno Unico. This framework rejects a masking of mental health in the collection, instead underscoring such taboo themes. In some cases, I choose more clinical translations of terminology to directly reference mental health discourse; in others I select more dated terms, such as “madness,” to gesture to a different framing of mental illness during the writing of Giorno Unico.
Urban waterfront revitalization in developing countries: the example of Zanzibar’s Stone Town

Field: Social Sciences (Social Sciences)

Urban waterfront redevelopment, in port cities and other cities on water, is still largely confined to advanced countries. However, it is now impacting upon developing countries as they seek to revive historic cities in post‐colonial contexts, including Islamic renewal, urban conservation and tourism development. These trends raise a variety of policy issues and problems, increasingly debated in an expanding literature, and invite comparison between contrasted case studies. This paper attempts to situate Zanzibar’s Stone Town waterfront within a theoretical framework originally based on European and North American experience but increasingly influenced by global trends.
Influence of fictitious bristle parameters in dynamic friction models

Field: Engineering (Physical Sciences)

In this study, the influence of bristle parameters in dynamic friction models is investigated, in particular in the LuGre and FrD2 models. These models contain internal states to better capture the friction behavior. The FrD2 model, a second-order dynamic friction model, aims at higher accuracy. The investigation focuses on how the independent variation of the bristle stiffness and the damping parameters affects the model behavior, especially considering the practical approximations used in determining the damping coefficient.
Tranexamic acid in cardiac surgery: a systematic review and meta-analysis (protocol)

Field: Medicine (Health Sciences)

Introduction Bleeding during cardiac surgery is associated with increased morbidity and mortality. Tranexamic acid is an antifibrinolytic with proven efficacy in major surgeries. Current clinical practice guidelines recommend intraoperative use in cardiac procedures. However, several complications have been reported with tranexamic acid including seizures. This review intends to summarise the evidence examining the efficacy and safety of tranexamic acid in patients undergoing cardiac surgery. Methods/design We will search MEDLINE, Embase, PubMED, ACPJC, CINAHL and the Cochrane trial registry for eligible randomised controlled trials, the search dates for all databases will be from inception until 1 January 2019, investigating the perioperative use of topical and/or intravenous tranexamic acid as a stand-alone antifibrinolytic agent compared with placebo in patients undergoing open cardiac surgery. We categorised outcomes as patient critical or patient important. Selected patient-critical outcomes are: mortality (intensive care unit, hospital and 30-day endpoints), reoperation within 24 hours, postoperative bleeding requiring transfusion of packed red blood cells, myocardial infarction, stroke, pulmonary embolism, bowel infarction, upper or lower limb deep vein thrombosis and seizures. Those outcomes, we perceived as clinical experts to be most patient valued and patients were not involved in outcomes selection process. We will not apply publication date, language, journal or methodological quality restrictions. Two reviewers will independently screen and identify eligible studies using predefined eligibility criteria and then review full reports of all potentially relevant citations. A third reviewer will resolve disagreements if consensus cannot be achieved. We will present the results as relative risk with 95% CIs for dichotomous outcomes and as mean difference or standardised mean difference for continuous outcomes with 95% CIs. We will assess the quality of evidence using the Grading of Recommendations, Assessment, Development and Evaluation approach. Ethics and dissemination Formal ethical approval is not required as primary data will not be collected. The results will be disseminated through a peer-reviewed publication Trial registration number CRD42018105904
CERAMIC COATINGS USED IN CASTING PLUTONIUM AND ITS ALLOYS.

Field: Materials Science (Physical Sciences)

Many ceramic materials are inert to molten plutonium, but fragility and porosity of ceramic crucibles make them impractical for use in the plutonium foundry.Oxidized tantalum crucibles are inert to pure plutonium and to some of the low-melting -point alloys of plutonium.T'o take advantage of the ruggedness of metal crucibles, ceramic coatings inert to plutonium alloys at high temperatures that can be applied to metal or graphite crucibles and molds were developed.This report describes these coatings arid the processes by which they are applied.
The Nexus between Foreign Aid and Economic Growth of Pakistan A Cointegration Analysis

Field: Economics, Econometrics and Finance (Social Sciences)

There is extensive literature available that dissects the linkage between foreign aid and the growth of the economy. The key focus of the current study is to explore how aid received from foreign countries are linked with growth rate of Pakistan’s economy. The present study considers time series data from 1985 to 2019 and corelates the nexus of foreign aid and Pakistan’s GDP growth rate in the long as well as short run. The study examined one dependent variable which is GDP, and seven independent variables including official development assistance as foreign aid, population growth, inflation, trade, domestic saving, unemployment, and foreign direct investment by using ARDL method. Broad canvas of the foreign aid and growth rate nexus is the main limitation of the paper and other factors impacting economic growth could not be taken into consideration due to the non- availability of complete data. The results of the study conclude that foreign aid hurts the economic growth of Pakistan throughout the thirty-four years not only in the short run but in long run as well.
Functus Officio?

Field: Arts and Humanities (Social Sciences)

Abstract This chapter examines the meaning of the principle of functus officio. The expression is used to refer to the point when the arbitral tribunal has discharged its duty in full and can no longer act. This point is generally held to be when the tribunal has concluded all matters with which it has jurisdiction to deal pursuant to a particular arbitration agreement. But while the principle itself may be superficially straightforward, its scope and application in certain cases have raised issues. The chapter asks: When can the tribunal be sure that its mandate is complete, i.e. officio functus est? When, if ever, can the arbitrators definitively say that they are ‘free’ of their duties in an arbitration? It suggests that it would be wrong to believe that a tribunal has certainly finished its work when it sends the final award to the parties. In many jurisdictions and under the leading arbitration rules, there will still be a continuing but reduced mandate to correct, interpret, and/or revise the award and perhaps to issue additional awards.
Morphology and Ultrastructure of the Alimentary Canal of Oriental Fruit Fly Bactrocera dorsalis (Hendel) (Diptera: Tephritidae) (I): The Structure of the Foregut and Cardia

Field: Agricultural and Biological Sciences (Life Sciences)

membrane and it is surrounded by a well-developed visceral circular muscle. The cardia is located between the foregut and the midgut, and includes the midgut epithelium in the outer portion of the cardia and the foregut epithelium in the inner portion. The oesophageal epithelium extends into the cardia to form the cardial valve. Both the longitudinal and the circular muscles beneath the oesophageal epithelium form a sphincter to control the entrance of food to the midgut and prevent the regurgitation of the midgut contents. The peritrophic membrane is secreted and forms from the surface of microvilli of the midgut at the anterior part of the cardia.
Survey of the Prevalence and Incidence of Foliar and Panicle Diseases of Sorghum Across Production Fields in Niger

Field: Agricultural and Biological Sciences (Life Sciences)

Background and Objective: In Niger, sorghum ranks second as the most important cereal after pearl millet and is used primarily as a staple food and fodder.In 2019, an extensive survey of the occurrence and distribution of foliar and panicle diseases affecting sorghum in farmersʼ fields from major production regions of Niger was conducted.Materials and Methods: A total of 121 fields in the regions of Tillabéri, Tahoua, Dosso and Maradi along paved and unpaved roads, including National and Secondary (RN1, RN2, RN3) were surveyed.In each field, 60 plants at late flowering to hard dough stages of development were assessed using a W-shaped pattern.Results: The study documented 21 different sorghum diseases, including anthracnose, long smut, oval leaf spot, leaf blight, head smut and zonate leaf spot.The most prevalent diseases were anthracnose, leaf blight, oval leaf spot, rough leaf spot and long smut.The highest mean incidence of anthracnose, leaf blight and rough leaf spot was recorded from Maradi, whereas, the regions of Dosso and Tahoua exhibited the highest mean oval leaf spot incidence.The highest incidence of long smut and zonate leaf spot was recorded in fields in Dosso region.Locations with highest incidence of these diseases can be considered ʻhot spotsʼ for resistance evaluations.Conclusion: This study is significant because for the 1st time it provides researchers, funding and governmental agencies in Niger a guide on the occurrence, distribution, prevalence and ʻhot spotsʼ for sorghum diseases.
Successful Pregnancy Outcome in a Patient with Protein S Deficiency: A Case Report

Field: Medicine (Health Sciences)

Protein S is a vitamin K-dependent anticoagulant and has a central role in the regulation of coagulation. The mechanism of action of protein S has been one of the least understood amongst the vitamin K-dependent coagulation proteins. A deficiency of protein S predisposes to recurrent thromboembolism and fetal loss. Here we report a case of protein S deficiency in a 28- year-old pregnant woman, who had a history of complete abortion at 22 of weeks of gestation and her 2nd pregnancy was managed properly with a successful fetal outcome.Birdem Med J 2016; 6(2): 134-135
Psychological Screening Inventory as a predictor of college student adjustment.

Field: Business, Management and Accounting (Social Sciences)

This project aims to create a more academic analysis, building on existing practitioner and professional literature, of the merits and de-merits of FRSSE (Financial Reporting Standard for Smaller Entities) adoption by UK SMEs. Adoption of FRSSE will be treated as amenable to cost-effectiveness analysis (Friedlob and Plewa, 1992), focusing both on a variety of costs (eg compliance costs, opportunity costs) and a variety of benefits (eg superior financial performance, greater flexibility) (eg Jackson, 1997). It aims to build on earlier attempts to gauge the costs/benefits of FRSSE by the likes of McAleese (2001), Murphy and Page (1998), and ICAS (2002). Our project is of greater detail and scope, adopts an explicit cost-effectiveness methodology (Friedlob and Plewa, 1992), and extends treatment from the accounting practitioner base to SMEs more generally. Further, it involves a radical advance, in terms of instrumentation, statistical methodology and analytical framework. In essence, the proposal is to create two new instruments for measuring the cost-effectiveness of FRSSE in a UK context (CCAB, 1996); a postal questionnaire and an administered questionnaire. Using the FAME database as a sampling frame for UK SMEs, 2,200 questionnaires will be sent to SMEs and accounting practitioners in the UK. Key issues addressed will be: features of FRSSE users, benefits and costs of FRSSE adoption, structural change of FRSSE, and prospects of (and needs for) an international FRSSE.
Infection Effect of Nomuraea riley MZ060806-XW against Helicoverpa armigera Larvae

Field: Agricultural and Biological Sciences (Life Sciences)

[Objective] The propose was to use the Nomuraea rileyi to make the biological control of Helicoverpa armigera.[Method] The pathogenicity research was conducted on the 2nd and 3nd instar larvae of H.armigera with conidia of N.rileyi MZ060806-XW under 5 different concn.of 3.5×104-3.5×108 spores/m inoculated by dipping method.[Result] The pathogenicity of conidia of N.rileyi MZ060806-XW to the mortality rate of the 2nd and the 3nd instar larvae was 84.68% and 82.23% resp.under concn.of 3.5×108 spores/ml on 8th day.LC50 of the 2nd and 3nd instar larvae were 3.975×104 and 7.794×104 spores/ml on 8th day.Under 5 concn.of 3.5×104-3.5×108 spores/ml,the LT50 of the 2nd instar larvae were 9.774,6.322,5.415,4.559 and 4.051 d resp.and that of the 3nd instar larvae was respectively 9.462,6.842,5.365,4.636 and 4.177 d.With the increase of spore concn.,the LC50 time was gradually shortened and the insect mortality was gradually increased;with the process of the drug application time,the LC50 concn.was gradually decreased.[Conclusion] The control effect of N.rileyi MZ060806-XW on the 2nd instar larvae of H.armigera was higher than that on 3nd instar larvae.N.rileyi used in the biological control of the pests had the value of development and utilization.
“Building the World of Tomorrow”

Field: Arts and Humanities (Social Sciences)

Although many associate eugenics with Nazi Germany, the United States employed a broad-based eugenics program that continued well into the 1970s. Twenty-thousand sterilizations were performed in California between 1909 and 1976 and North Carolina's eugenics program, which allowed social workers to mandate the sterilization of anyone with an IQ below seventy, operated until 1977. As recently as 2013, the California Fourth District Appellate Court ruled that a developmentally disabled adult with "mild mental retardation" could be sterilized by court order, and in 2015 then-Presidential nominee Donald J. Trump publicly mocked New York Times journalist Serge Kovaleski for his physical impairment. The able-bodied bias that permeates contemporary American life is not limited to politics, however. Instead it is supported and disseminated by visual culture, which is dominated by what Lennard J. Davis termed the "hegemony of normalcy" and what Robert McRuer calls "compulsory able-bodiedness." Art plays a dynamic role in perpetuating eugenic discourse and institutionalizing ableism, and the "spectacle of able-bodied heteronormativity" that underlies much of contemporary American discourse crystallized during the 1930s. To demonstrate my point, this chapter illustrates the ways in which the sculptural program of the 1939 New York World's Fair, subtitled "Building the World of Tomorrow" and considered one of the most important cultural moments of the twentieth century, naturalized the "Average American" as white, fit, and heterosexual.
Learning processes in higher education: Comparing the impact of cognitive & motivational variables on specific & global measures of achievement

Field: Psychology (Social Sciences)

The aim of this study was to investigate the impact of motivational and cognitive processes on several achievement outcomes. Academic achievement was assessed through final percentage and three tasks assessing three different levels of knowledge (acquisition of knowledge, understanding of principles and application of concepts). The relation between achievement and self-efficacy beliefs, goal orientation, learning strategies and self-regulation was investigated while controlling for student’s previous performance. The participants were 217 students from the engineering faculty at the Universite catholique de Louvain in Belgium. The students were at the beginning of their third year of study. Data were analyzed through stepwise regression. The results mainly highlighted that final percentage is essentially modulated by motivational factors (mastery goal), whereas the performance to specific tasks was related with cognitive factors (deep processing and surface processing). Moreover, the results also revealed that the impact of self-efficacy beliefs on achievement outcomes vanished when student’s previous performance are controlled for. The implications of our results on the understanding of the relation between learning process and academic achievement have been discussed.
Contribution to the knowledge of Chinese Phasmatodea XI: New taxa and new nomenclature of Medaurini (Phasmatidae: Clitumninae) from China

Field: Agricultural and Biological Sciences (Life Sciences)

Ho, Wai-Chun George (2021): Contribution to the knowledge of Chinese Phasmatodea XI: New taxa and new nomenclature of Medaurini (Phasmatidae: Clitumninae) from China. Zoological Systematics 46 (3): 234-239, DOI: 10.11865/zs.2021305, URL: https://www.mendeley.com/catalogue/0e7010a6-1715-3717-a540-c6cd22f58d0e/
Measurements of quarkonium production in p-Pb and Pb-Pb collisions with ALICE at LHC

Field: Physics and Astronomy (Physical Sciences)

ALICE (A Large Ion Collider Experiment) is devoted to the study of heavy-ion collisions at LHC energies. In such collisions a deconfined state of hadronic matter, the Quark-Gluon Plasma (QGP), is formed. Quarkonium states are important probes to study the QGP evolution since their formation happens early during the collision and their production rate is modified in the interaction with the medium. The latest ALICE results on quarkonium production in Pb-Pb and p-Pb collisions will be presented and discussed.
Low-Rank STRAP Filter Via Alternative Unfolding HOSVD for FDA-MIMO Radar

Field: Computer Science (Physical Sciences)

The multidimensional structure of frequency diverse array (FDA) multiple-input-multiple-out (MIMO) radar signals has attracted a lot of attention. It allows to extend conventional space-time adaptive processing to space-time-range adaptive processing (STRAP). In this letter, we propose two tensorial filters for FDA-MIMO-STRAP, called the clutter subspace filter and the clutter-free subspace filter, which exploit the low-rankness of the clutter to achieve better clutter suppression in a small auxiliary training data scenario. The proposed method makes use of the alternative unfolding higher order singular value decomposition with different dimensional partitions. Numerical results demonstrate the effectiveness of the proposed filters over existing low-rank vectorial and tensorial methods.