jimnoneill/paper-to-field-training huggingface dataset:
Blood vessels constitute the first organ in the embryo and form the largest network in our body but, sadly, are also often deadly. When dysregulated, the formation of new blood vessels contributes to numerous malignant, ischemic, inflammatory, infectious and immune disorders. Molecular insights into these processes are being generated at a rapidly increasing pace, offering new therapeutic opportunities that are currently being evaluated.

Field: Medicine (Health Sciences)

Vessel growth: modes and impact on health Small blood vessels consist only of endothelial cells (ECs), whereas larger vessels are surrounded by mural cells (pericytes in medium-sized and smooth muscle cells (SMCs) in large vessels). Vessels can grow in several ways. Vasculogenesis refers to the formation of blood vessels by endothelial progenitors, angiogenesis and arteriogenesis refer to the sprouting and subsequent stabilization of these sprouts by mural cells, and collateral growth denotes the expansive growth of pre-existing vessels, forming collateral bridges between arterial networks. Both capillary angiogenesis and arterial growth are targets for therapy, as distal capillaries distribute the flow while proximal arterioles provide bulk flow to the tissue. When vessel growth is dysregulated, it has a major impact on our health and contributes to the pathogenesis of many disorders, some quite unexpected. Indeed, a long list of disorders is characterized or caused by excessive angiogenesis. Historically, the best known are cancer, psoriasis, arthritis and blindness, but many additional common disorders such as obesity, asthma, atherosclerosis and infectious disease are included, and the list is still growing (Tab le 1). Several congenital or inherited diseases are also caused by abnormal vascular remodeling (Tab le 1). In addition, insufficient vessel growth and abnormal vessel regression not only cause heart and brain ischemia, but can also lead to neurodegeneration, hypertension, pre-eclampsia, respiratory distress, osteoporosis and other disorders (Tab le 2). Few other processes have as daunting an impact as angiogenesis on the well-being of so many people worldwide. Recent advances in the understanding of molecular, genetic and cellular mechanisms of vessel growth and their possible implications for medicine will be discussed in this overview. Endothelial progenitors
Adaptive SVR-HDMR Metamodeling Technique for High Dimensional Problems

Field: Computer Science (Physical Sciences)

Modeling or approximating high dimensional, computationally-expensive problems faces an exponentially increasing difficulty, the "curse of dimensionality". This paper proposes a new form of high dimensional model representation (HDMR) by utilizing the support vector regression (SVR), termed as adaptive SVR-HMDR, to conquer this dilemma. The proposed model could reveal explicit correlations among different input variables of the underlying function which is unknown or expensive for computation. Taking advantage of HDMR's hierarchical structure, it could alleviate the exponential increasing difficulty, and gain satisfying accuracy with small set of samples by SVR. Numerical examples of different dimensionality are given to illustrate the principle, procedure and performance of SVR-HDMR.
A FIVE-FACTOR MEASURE OF SCHIZOTYPAL PERSONALITY DISORDER

Field: Psychology (Social Sciences)

The current study provides convergent, discriminant, and incremental validity data for a measure of schizotypia from the perspective of the Five-Factor Model (FFM) of general personality structure. Nine schizotypia facet scales were constructed as maladaptive variants of respective facets of the FFM (e.g., Aberrant Ideas as a maladaptive variant of FFM Openness to Ideas). On the basis of data from 143 undergraduates the convergent validity of these nine facet scales was tested with respect to 11 established measures of schizotypia and the respective facets of the FFM. Discriminant validity was tested with respect to other personality disorders and facets from other FFM domains. Incremental validity was tested with respect to the ability of the FFM schizotypia facet scales to account for variance in two established measures of schizotypia, after variance accounted for by respective FFM facets and other established measures of schizotypia were first removed. The findings support the validity of these new facet scales as measures of schizotypia and as maladaptive variants of the FFM.
Design of an intelligent sensor network for solar panels

Field: Engineering (Physical Sciences)

Energy industry observers have considered solar energy as an alternative and practical source of energy generation. It is predicted that the world will undergo a major transition in energy sources over the next few decades and clearly solar is one of the popular energy sources. This project is to design an intelligent wireless sensor network for solar panels in Microgrid. Collection of solar energy profile is done through intelligent energy sensors and data which collected will be transmitted using GPRS. From hardware aspect, the system consists of several major controlling components. Intelligent sensors including contact temperature sensor and pyranometer which is able to measure sun light intensity are going to be used. In order to transfer the data we get from the building roof to the lab, Telit GPRS Evaluation Kit has been included too. As from software aspect, in order to control the GPRS Evaluation Kit, AT commands specially for GPRS devices and Python language matching AT commands have been used. To get the data from the Internet we try to use Visual Basic 6.0 to build a form to listen to the designated IP address and gain data. A graphical user interface (GUI) named ION Vista has been introduced for implementation of data display. The data we get can be stored into the database consolidated with ION software and we can invoke them in it. The whole system combines both aspects as mentioned above and performs data transmitting. Further improvement and enhancement are required to overcome the inconvenient way to send and receive data of the GPRS. This can be achieved by using effective software and language for the GPRS system.
Unilateral Refusals to License in the U.S.

Field: Social Sciences (Social Sciences)

Most antitrust claims relating to intellectual property involve challengesto agreements, licensing practices or affirmative conduct involving the useor disposition of the intellectual property rights or the products theycover. But sometimes an antitrust claim centers on an intellectual propertyowner's refusal to use or license an intellectual property right, perhapscoupled with efforts to enforce the intellectual property right againstinfringers. The allegation may be that the intellectual property right isso essential to competition that it must be licensed across the board, orthat a refusal to license it to one particular party was discriminatory, orthat in context a refusal to license helped a monopolist to acquire ormaintain market power.Claims based on a unilateral refusal to license - the subject of thischapter - present important issues at the center of the tension betweenantitrust and intellectual property. The antitrust and intellectualproperty laws are not necessarily in conflict. For the most part they servecomplementary goals, though each must limit the scope of the other.Unilateral refusal to license cases, however, cut to the heart of theintellectual property owner's right to exclude others from practicing theintellectual property. As such, efforts to invoke antitrust law in thiscontext deserve special scrutiny.Section 2 reviews the basic principles relating to unilateral refusals tolicense intellectual property rights. Section 3 discusses in detail thevarious sets of circumstances in which antitrust plaintiffs argue forexceptions to those basic rules. Section 4 distinguishes unilateral fromconcerted and conditional refusals to deal.
Optimization of protective agent for Lactobacillus bulgaricus

Field: Agricultural and Biological Sciences (Life Sciences)

Objective To investigate the additions of four protective agents for Lactobacillus bulgaricus.Methods Lactobacillus bulgaricus was used as the experimental strains;orthogonal experiments were conducted to determine the additions of the four protective agents,using the counts of viable bacteria′s in the freeze-dried powder as the indicator.Results The optimal proportion of the protective agent of Lactobacillus bulgaricus was lactose : sodium glutamate : ascorbic acid : skimmed milk powder= 3:1:2:7,among which skimmed milk powder showed a highly protective effect on the bacteria(P0.01),and lactose showed a remarkable effect(P0.05).Conclusion By optimizing additive amount of four protective agent,we provide the foundation for freeze dry process of Lactobacillus bulgaricus.
SGSEAM:Assessing serious game frameworks from a stakeholder experience perspective

Field: Computer Science (Physical Sciences)

Assessment of serious game frameworks is emerging as an
important area of research. This paper describes an assess-
ment mechanism called the Serious Game Stakeholder Ex-
perience Assessment Method (SGSEAM). SGSEAM is de-
signed to provide detailed insights into the strengths and
shortcomings of serious game frameworks through a stake-
holderperspectivebased approach. In this paper, we report
on
the use of SGSEAM to assess Makahiki, an open source se-
rious game framework for sustainability. Our results provi
de
useful insights into both Makahiki as a serious game frame-
work and SGSEAM as an assessment method
Novel alanine serine cysteine transporter 2 (ASCT2) inhibitors based on sulfonamide and sulfonic acid ester scaffolds

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The neutral amino acid transporter alanine serine cysteine transporter 2 (ASCT2) belongs to the solute carrier 1 (SLC1) family of transport proteins and transports neutral amino acids, such as alanine and glutamine, into the cell in exchange with intracellular amino acids. This amino acid transport is sodium dependent, but not driven by the transmembrane Na+ concentration gradient. Glutamine transport by ASCT2 is proposed to be important for glutamine homoeostasis in rapidly growing cancer cells to fulfill the energy and nitrogen demands of these cells. Thus, ASCT2 is thought to be a potential anticancer drug target. However, the pharmacology of the amino acid binding site is not well established. Here, we report on the synthesis and characterization of a novel class of ASCT2 inhibitors based on an amino acid scaffold with a sulfonamide/sulfonic acid ester linker to a hydrophobic group. The compounds were designed based on an improved ASCT2 homology model using the human glutamate transporter hEAAT1 crystal structure as a modeling template. The compounds were shown to inhibit with a competitive mechanism and a potency that scales with the hydrophobicity of the side chain. The most potent compound binds with an apparent affinity, Ki, of 8 ± 4 µM and can block the alanine response with a Ki of 40 ± 23 µM at 200 µM alanine concentration. Computational analysis predicts inhibitor interactions with the binding site through molecular docking. In conclusion, the sulfonamide/sulfonic acid ester scaffold provides facile synthetic access to ASCT2 inhibitors with a potentially large variability in chemical space of the hydrophobic side chain. These inhibitors will be useful chemical tools to further characterize the role of ASCT2 in disease as well as improve our understanding of inhibition mechanisms of this transporter.
Pengembangan Modul Pembelajaran Kontekstual disertai Concept Mapping pada Materi Elastisitas dan Hukum Hooke

Field: Social Sciences (Social Sciences)

This research aims to develop and determine the quality of the contextual learning module accompanied by a concept mapping of elasticity material andlaw Hooke in class XI IPA MA Mu'allimat NW Pancor students. This type of research is research and development. The method used in this research is 4-D method, which consists of the stages of define, design, development and dissemination. This research is limited to the stage, development namely the development test on a limited scale. The data in this study were analyzed descriptively qualitatively. The research subjects included 3 lecturers and 3 physics teachers as validators, and students of class XI IPA 1 MA Mu'allimat NW Pancor as respondents. The validation of lecturers and physics teachers both resulted in a score of 3.85 and the development trial on a limited scale resulted in a score of 3.88. All research results indicate that the module is feasible to be developed.
Development and Evaluation of Shortcut-Derived Behaviorally Anchored Rating Scales

Field: Psychology (Social Sciences)

The purpose of the present study was to evaluate a shortcut method for developing Behaviorally Anchored Rating Scales (BARS). The developmental method included two novel steps: (a) the performance of judgmental cluster analysis to define scales and (b) the direct placement of behavioral incidents on the scales rather than the use of the retranslation step. Two groups of six students each developed shortcut BARS through using an instructional booklet. The BARS were developed to evaluate teaching performance of college instructors. The sets of shortcut scales constructed by the two groups and a traditionally developed BARS were then distributed randomly to students in nine classes who were asked to evaluate both their class instructors and the instructors in their immediately preceding class. The shortcut scales, in comparison with the traditional BARS, were slightly more reliable. Both sets of scales had approximately the same degree of leniency error. The shortcut scales were in general somewhat less adequate in terms of halo error and discriminant validity, but were almost equivalent on these characteristics after the scales with very low reliabilities had been dropped. The results did not support the use of the judgmental cluster analysis, but did indicate that the retranslation step may not be necessary to develop BARS.
A Vision-Based Tactile Sensing System for Multimodal Contact Information Perception via Neural Network

Field: Computer Science (Physical Sciences)

Typically, robotic dexterous hands are equipped with various sensors to acquire multimodal tactile information, which is an important way for robots to perceive and interact with the environment.Vision-based tactile sensors have been widely developed due to their simple structure and high resolution.It adopts specialized optical design to convert different contact information into different signal responses, such as recognizing contact force information based on marking method, obtaining contact shape information based on photometric stereo method, and so on.However, the current mainstream vision-based tactile sensing systems tend to adopt isolated optical design strategies for different modal tactile information, introducing limitations in system integration.This article proposes a vision-based tactile sensing strategy for multimodal tactile information using only reflected light field information.The specific implementation of the vision-based tactile sensor and the recognition algorithm for sensing multiple tactile information simultaneously are described in detail.The results show that the tactile sensing strategy does not need to design different optical structures for different modal tactile information, but only uses a simple reflection layer combined with a neural network to sense multi-modal tactile information, which reduces the complexity of the tactile system.In addition, the system achieves a force error of 0.2 N and a pose error of 0.41 °, and shows excellent precision and recall in localization and classification tasks, demonstrating the potential for multimodal tactile integration in various fields.
Analisis Pengaruh Orientasi Kewirausahaan, Inovasi, dan Kapabilitas Pemasaran terhadap Keunggulan Bersaing pada UKM Olahan Ikan di Semarang

Field: Business, Management and Accounting (Social Sciences)

This study aimed to find out the influence of entrepreneurial orientation, innovation and marketing capabilities on competitive advantage. The research population comprised Fish Processing Business in Semarang City. The sample was selected by means of the purposive sampling technique. The sample was 100 companies. The data were collected by a questionnaire, interviews, and documentation. This research uses Structural Equation Modeling (SEM) analysis technique using AMOS 24.0 analysis tool. The test results using Structural Equation Modeling (SEM) analysis techniques indicate that the model is in accordance with population data. The results of the study showed that entrepreneurship oriented , innovation and marketing capabilities had a significant positive effect on competitive advantage. Used by analyzer for example validity test, test reliabilitas, and hipotesis test use modelling equation structural (SEM).
Antihypertensive prescribing patterns and hypertension control in females of childbearing age

Field: Medicine (Health Sciences)

Abstract Purpose The use of angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) to treat hypertension (HTN) during pregnancy presents well-established risks to a developing fetus. A cross-sectional study was conducted to evaluate the current state of antihypertensive prescribing and contraceptive use in females of childbearing age within a large safety-net health system. Methods The retrospective cross-sectional study focused on females aged 18-49 years with a documented diagnosis of HTN. The proportion of patients prescribed an ACE inhibitor or ARB and using a documented form of contraception was calculated. Documented forms of contraception included oral contraceptives, intrauterine devices, injections, implants, and surgical intervention. Results A total of 4,187 patients were identified from the HTN registry; after application of exclusion criteria 3,045 patients were included in the study population. The mean age was 39 years (range, 18-49 years). The most frequently prescribed classes of antihypertensive medications were ACE inhibitors and ARBs (one or the other was used by 1,146 patients [37.6%]), followed by thiazide diuretics (n = 710, 23.3%) and calcium channel blockers (n = 599, 19.7%). Of the 1,146 patients prescribed an ACE inhibitor or ARB, 553 (48%) were using a documented form of contraception. Conclusion Rates of ACE inhibitor or ARB prescribing to females of childbearing age were high despite the teratogenic risks, and fewer than half of patients had documented protection from pregnancy. Provider and patient education and potential creation of best practice alerts in the electronic medical record regarding the risks of using ACE inhibitors and ARBs in females of childbearing age are warranted.
Data from: A shift from phenol to silica-based leaf defenses during long-term soil and ecosystem development

Field: Environmental Science (Physical Sciences)

The resource availability hypothesis predicts that plants adapted to infertile soils have high levels of anti-herbivore leaf defenses. This hypothesis has been mostly explored for secondary metabolites such as phenolics, while it remains underexplored for silica-based defenses. We determined leaf concentrations of total phenols and silicon (Si) in plants growing along the 2-million-year Jurien Bay chronosequence, exhibiting an extreme gradient of soil fertility. We found that nitrogen (N) limitation on young soils led to a greater expression of phenol-based defenses, whereas old, phosphorus (P)-impoverished soils favored silica-based defenses. Both defense types were negatively correlated at the community and individual species level. Our results suggest a tradeoff among these two leaf defense strategies based on the strength and type of nutrient limitation, thereby opening up new perspectives for the resource availability hypothesis and plant defense research. This study also highlights the importance of silica-based defenses under low P supply.
LHD ICHVOLT #154582.1

Field: Physics and Astronomy (Physical Sciences)

Ion Cyclotron Range of Frequencies (ICRF) heating system to launch fast waves (Ion Cyclotron Range of Frequencies (ICRF) waves) to heat plasma particles by wave-particle interaction. Raw data are forward and reflected power and voltage of transmission lines, 3.5 U/L and 4.5 U/L.
DESAIN RUANG DAN PENCAHAYAAN BUATAN UNTUK MENDUKUNG SUASANA KONTEMPLASI PADA GEREJA KATOLIK REGINA CAELI, JAKARTA

Field: Arts and Humanities (Social Sciences)

Title: Space and Lighting Design to Support Contemplation Atmosphere in Regina Caeli Catholic Church, Jakarta The study examines how the light and space in the Church of Regina Caeli able to reinforce the presence of God?s impression and support contemplation?s atmosphere. The discussion reviewed by spatial elements (lobby/narthex, pulpit/nave, and sanctuary/chancel), enclosure elements (floors, walls, ceilings), and interior elements (furniture, decoration, and symbols). The lighting aspects explored are physical aspect (light source, technique, light distribution, colour, and level of light) and perception aspect (psychology of light). The study shows that the lighting support contemplation by emphasizing the sacred-secular space?s transition and strengthen the sacred space?s orientation. The contemplation is weakened due to the excessive number of liturgical symbols that blurring the people?s focus. As a pluriform church, Regina Caeli applying the combined effect of vertical and horizontal shape and space, but the lighting only emphasizes the horizontal effect that caused the impression of a church that is humane.
A Serologic Survey of Military Personnel and Dogs in Thailand and South Vietnam for Antibodies to Arboviruses, Rickettsia tsutsugamushi, and Pseudomonas pseudomallei

Field: Medicine (Health Sciences)

SUMMARY A serologic survey for antibodies to group A and group B arboviruses, Pseudomonas pseudomallei , and Rickettsia tsutsugamushi was conducted in Thailand. Serum samples were collected from 232 sentry dogs and 222 human dog handlers at the time of their arrival in that country and quarterly thereafter for 1 year. Results of serotests with the 4 antigens were negative for dogs and handlers on arrival. Both dogs and handlers developed hemagglutinationinhibiting ( hi ) antibodies to group A arboviruses at the rate of 3% annually. Rates of change of serotest results to positive for group B arbovirus antibody ( hi ) were 41% for dogs and 34% for human handlers. Neither human handlers nor dogs developed detectable antibodies against P. pseudomallei or R. tsutsugamushi . Seasonal differences in changes to positive results in tests for group B arbovirus antibody occurred, with the highest incidence during the period September through December. Geographic differences occurred with the changes in test results at different bases, varying from 22 to 51%. Dogs developed detectable antibody in 55% of the collection periods, and, therefore, may be of value as sentinel animals. A survey at Da Nang Air Base, South Vietnam, consisted of single samples from each of 50 sentry dogs. Serologic analysis was conducted for antibodies to the same 4 antigens surveyed in Thailand. These dogs were test negative for antibody to group A arboviruses, P. pseudomallei , and R. tsutsugamushi . Eighty-two percent had titers (1:40 dilution or greater) to group B arboviruses.
Studies on Cytokinins in Watermelon Seeds

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract Extracts of immature seeds of watermelon contain three cytokinins which are adsorbed on Dowex 50W ion exchange resin. The Rf of the fastest moving factor is similar to that of zeatin. The slowest moving factor is insoluble in n ‐butanol and shows some resemblance to zeatin ribotide. The chromatographic properties of the second factor are, however, different from those of any of the known cytokinins and is believed to be new to literature.