jimnoneill/paper-to-field-training huggingface dataset:
Electrophoresis and size-exclusion chromatography of humic substances extracted from detritus and soils of different geneses

Field: Environmental Science (Physical Sciences)

Electrophoresis in 10% polyacrylamide gel in the presence of denaturants and size-exclusion chromatography in Sephadex G-75 in 7 M urea were used for the comparative analysis of humic substances isolated from a typical chernozem, soddy-podzolic soil, and chestnut soil and from the easily decomposable organic matter (plant detritus) contained in these soils. After the electrophoresis, the gel with naturally colored bands of humic substances was further stained with a dye specific for proteins by immersing into a solution containing Coomassie Brilliant Blue R-250 and CuSO4. The electrophoretic and chromatographic analyses showed that humic substances from the soils and the corresponding detritus fractions significantly differed in the intensity of the natural color of the electrophoretic fractions, the molecular-weight distribution, and the color of the electrophoretic fractions colored by the protein-specific dye (which was first discovered in this study). The hypothesis of Tyurin and Aleksandrova suggesting that the transformation of humus sources (plant detritus) into humic substances proceeds in the direction from the high-molecular compounds to the low-molecular compounds was experimentally confirmed.
LIME CHLOROSIS IN SEEDLING ESTABLISHMENT ON CALCAREOUS SOILS

Field: Agricultural and Biological Sciences (Life Sciences)

S ummary A comparison has been made amongst a number of species as to the ability of green and chlorotic foliage to fully reverse induced leaf water‐deficits. In all cases it was found that chlorosis conferred a reduction in the ability of the affected leaf to resaturate, compared with green leaves of the same species. Three distinct patterns of behaviour of chlorotic leaves were found in this respect. Permanent damage was caused by leaf water‐deficits as low as 10% in some species, whilst chlorotic leaves of others could withstand 60% water‐deficits before irreversible damage was detected. Green foliage of chlorosis‐resistant species were able to tolerate deficits of from 60 to 85% before resaturation ability was impaired. The ecological implications of these findings are considered, with respect to the establishment and survival of chlorosis‐resistant and susceptible seedlings on calcareous soils subject to periodic droughts.
Tourism Enterprises in the South Pacific

Field: Social Sciences (Social Sciences)

As with most travel-based enterprises, Indigenous-run tourism enterprises in Aotearoa New Zealand and elsewhere in the Pacific were severely affected by Covid-19. The collapse of global travel forced companies to respond in different ways to cope with the pandemic. However, few studies have examined how Indigenous enterprises reacted to the volatility of tourism and the measures Indigenous people adopted both to protect their people and to stay afloat. Based on empirical research conducted in Aotearoa New Zealand and the Cook Islands, this chapter sheds light on the difficulties the pandemic-enforced border closures brought for Indigenous enterprises, but it also focuses on how Indigenous owners and managers of tourism enterprises have re-prioritised their employees and communities and adapted in the face of pressure. Furthermore, this chapter exposes the values underpinning Indigenous enterprises' decision-making, which influence how they adapt. For some, their purpose has been culturally embedded, determining what is best for their whānau (family), their people, and the whenua (land). This chapter asserts that in response to shocks such as the global coronavirus pandemic, Indigenous enterprises have exercised their tino rangatiratanga (self-determination).
The effect of ethyl acetate fraction of Marsilea crenata presl. leaves in increasing osterix expression in hFOB 1.19 cells

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Marsilea crenata Presl. leaves contain phytoestrogens that is suspected to play a role in increasing bone formation. Bone formation activity is defined by the expression of Osterix, a transcription factor that plays a key role in bone development. The aim of this study is to show that the ethyl acetate fraction of Marsilea crenata Presl. leaves can increase bone formation process in hFOB 1.19 cells in a TNF-α dependent manner, by measurement of Osterix. The hFOB 1.19 cells were grown in 24-well microplates and treated with 10 ng/ml TNF-α for 24 hours. The ethyl acetate fraction of Marsilea crenata Presl. leaves were also added in concentrations of 62.5, 125, and 250 ppm. A positive control was employed, at a concentration of 2.5 g/L of genistein. The expression of osterix was examined using an immunocytochemistry technique with CLSM to assess bone forming activity. The results show that ethyl acetate fraction Marsilea crenata Presl. leaves can boost osterix expression in hFOB 1.19 cells, with optimal concentration was 250 ppm at p<0.005. The ethyl acetate fraction of Marsilea crenata Presl. leaves can increase Osterix in osteoblast hFOB 1.19 cell, indicating improved bone forming activity.
mHealth Self-Monitoring Model for Medicine Adherence of Patients With Diabetes in Resource-Limited Countries: Structural Equation Modeling Approach (Preprint)

Field: Health Professions (Health Sciences)

BACKGROUND

The COVID-19 pandemic has led to serious challenges and emphasized the importance of using technology for health care operational transformation. Consequently, the need for technological innovations has increased, thus empowering patients with chronic conditions to tighten their adherence to medical prescriptions.

OBJECTIVE

This study aimed to develop a model for a mobile health (mHealth) self-monitoring system for patients with diabetes in rural communities within resource-limited countries. The developed model could be based on the implementation of a system for the self-monitoring of patients with diabetes to increase medical adherence.

METHODS

This study followed a quantitative approach, in which data were collected from health care providers using a questionnaire with close-ended questions. Data were collected from district hospitals in 3 South African provinces that were selected based on the prevalence rates of diabetes and the number of patients with diabetes treated. The collected data were analyzed using smart partial least squares to validate the model and test the suggested hypotheses.

RESULTS

Using variance-based structural equation modeling that leverages smart partial least squares, the analysis indicated that environmental factors significantly influence all the independent constructs that inform patients’ change of behavior toward the use of mHealth for self-monitoring of medication adherence. Technology characteristics such as effort expectancy, self-efficacy, and performance expectancy were equally significant; hence, their hypotheses were accepted. In contrast, the contributions of culture and social aspects were found to be insignificant, and their hypotheses were rejected. In addition, an analysis was conducted to determine the interaction effects of the moderating variables on the independent constructs. The results indicated that with the exception of cultural and social influences, there were significant interacting effects on other independent constructs influencing mHealth use for self-monitoring.

CONCLUSIONS

On the basis of the findings of this study, we conclude that behavioral changes are essential for the self-monitoring of chronic diseases. Therefore, it is important to enhance those effects that stimulate the behavior to change toward the use of mHealth for self-monitoring. Motivational aspects were also found to be highly significant as they triggered changes in behavior. The developed model can be used to extend the research on the self-monitoring of patients with chronic conditions. Moreover, the model will be used as a basic architecture for the implementation of fully fledged systems for self-monitoring of patients with diabetes.
A Comprehensive Multidimensional Conceptual Model to Assess the e-Governance Service Quality at Common Service Centers in India

Field: Social Sciences (Social Sciences)

E-governance is a new way of life where ITC (Information Technology and Communication) has believed to enhance the communication and services of government. It has reduced cost and time of availability and delivery of services to citizen and limited corruptions when compared to traditional way of availing government services. CSC is one of the core infrastructures under NeGP (National e-Governance Plan) in 2006 by GoI (Government of India). It envisages the socio-economic status of rural population by including them in development process and providing sustainable digital access. The main aim of CSC is to provide frontend delivery points for government (G2C), private and social sector organizations (B2C) to support for the benefit and upliftment of the rural community in remotest places. A large number of studies have been conducted by academics to measure the service quality of e-governance. But they did not come out with a comprehensive model for assessing the service quality of CSCs. The present systematic and descriptive research is undertaken with two main objectives- to review major e-governance G2C service quality models and to assess the key dimensions for developing a comprehensive multidimensional conceptual model for e-governance service quality of CSCs in India. The study found that information quality, system quality, institution-service quality, trust, usability, citizen (user) satisfaction and net benefit are key dimensions to assess the service quality of CSCs.
Methods of forecasting calculations of breakthrough wave at hydrodynamic accidents waterstorage dam

Field: Earth and Planetary Sciences (Physical Sciences)

The article gives the method of calculation of water storages dam at hydro technical accidents. From natural disasters floods (flooding of water in the area and settlements) by the frequency of occurrence of the phenomenon, the area of distribution and the annual material damage ranked first. Moreover, in recent years, the world has seen an increase in the number and extent of floods and the associated social and economic losses. Both at present and in the foreseeable future, floods as a natural disaster cannot be completely prevented everywhere and everywhere, they can only be weakened, localized and with timely warning to minimize material damage. Therefore, one of the largest floods in recent years, that occurred in the West Kazakhstan region in the spring of 2011 and which took place without casualties, resulted in the allocation of more than 19 billion tenge in damage recovery from damage. Unplanned and inconsistent with general measures during floods and floods, the descent of these reservoirs can exacerbate the effects of flooding. The technical condition of the channel dams is especially dangerous. In case of possible accidents on these dams, many settlements, thousands of enterprises, millions of hectares of agricultural land can get into the affected area. Based on the results of full-scale leveling surveys, forecasting calculations of the breakthrough of the water reservoir dams of Bartogay, Kapshagay and Kurty hydrounits have made. Attached graphics show a dependence of water consumption at the dam breakthrough on the distance from the dam gates.
HEM Impoundment—A Numerical Prediction Tool for the Water Framework Directive Assessment of Impounded River Reaches

Field: Environmental Science (Physical Sciences)

A novel prediction tool is presented as a component of the Habitat Evaluation Model (HEM), which allows the assessment of the ecological status of impounded water bodies based on environmental factors that were shown in literature to correlate with the abundance of benthic macro-invertebrates. Main model parameters are the observed grain sizes and depth-averaged flow velocities obtained from a hydrodynamic simulation. The tool was tested in three Austrian river reaches. It was found that the river lengths predicted to be ecologically affected by the impoundments were substantially shorter for mean flow conditions than previously assessed when employing a physical mapping approach. The differences disappeared for low discharge conditions. The numerical prediction tool allows us to perform a status assessment for discharge conditions, which are potentially more representative of the annual discharge spectrum than those within the in-situ observable range. This property, thus, bears the potential to facilitate the recommendation of sediment management strategies in impounded river reaches in the future.
The Role of BRDT in Esophageal Squamous Cell Carcinoma

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Esophageal squamous cell carcinoma (ESCC), the predominant subtype of esophageal cancer, remains a deadly malignancy due to the lack of effective therapies. Precision oncology, utilizing various techniques to identify patient-specific vulnerabilities for therapeutic intervention, has emerged as a promising approach for cancer treatment. Many clinical trials involving EGFR-targeted therapies in ESCC have failed, highlighting a need for the identification of novel therapeutic targets. Epigenetic alteration is one of the hallmarks of cancer and epigenetic factors are also widely dysregulated in ESCC. In this project, we sought to identify a therapeutic target for advancing precision medicine in ESCC. Using an unbiased method, we screened a curated list of epigenetic factors and found that a testis-specific epigenetic reader protein BRDT to be expressed and functional active in a significant portion of ESCC patients. While it does not affect cell proliferation, it is essential for cell migration. Transcriptomic profiling revealed extracellular matrix-related pathways are altered upon loss of BRDT, which could explain the decreased migratory potential. Chromatin occupancy profiling of BRDT uncovered its preferential occupancy of active promoters and enhancers. Subsequently, we found that genes dependent on BRDT are also targets of ΔNp63, a master transcription factor for squamous lineage commitment. Besides the common target genes, genomic co-localization of BRDT and ΔNp63 confirms the functional interplay between them. Knock-down of ΔNp63 or FAT2, a common target of BRDT and ΔNp63, phenocopies the loss of BRDT. Furthermore, overexpression of BRDT in a BRDT-negative ESCC cell line can enhance the expression of the ΔNp63-dependent gene expression program and significantly increase cell migration. To gain more mechanistic insight, we integrated chromatin topology data with epigenome profiles and found that BRDT and ΔNp63 co-localize at selected super enhancers to regulate ΔNp63-dependent transcription programs that promote cell migration. Strikingly, pharmacologically depleting BRDT recapitulates the effects of BRDT depletion. Collectively, these findings revealed the role of BRDT in ESCC and uncover the potential of BRDT as a novel therapeutic target for precision medicine in a subset of ESCC.
Yiddish Fiction and the Crisis of Modernity, 1905-1914 (review)

Field: Arts and Humanities (Social Sciences)

Few analyses of modern Yiddish literature can avoid the sense of crisis—impending, encountered, rarely averted or overcome—that anchors Mikhail Krutikov's title. At the same time, few can avoid the surprising sense of hope that he finds in the literature of the decade leading up to World War I. Yiddish culture thrived in this age of revolution marked by an energizing range of political, economic, and social [End Page 888] possibilities. Krutikov's study offers the most detailed, nuanced view to date of both the crises and optimism that defined Jewish history and Yiddish literature in this volatile period. The book's major strength lies in its exploration of what its author calls the "ideological polyphony" of the many texts he examines. Thus informed by Bakhtin, but equally by Lukacs, and even more profoundly by the Russian literary historian Yurii Lotman and by Marxist Yiddish critics silenced by Stalin, Krutikov locates his literary subjects within the discourses that first produced them: the Eastern European, primarily Russian milieu from which most American scholars have wrested them.
Photo-Targeted Nanoparticles

Field: Chemistry (Physical Sciences)

We report a novel and simple proof-of-concept of a nanoparticulate system that targets any tissue selectively upon illumination. Nanoparticles were covalently functionalized with the amino acid sequence YIGSR, which adheres to the beta1 integrins present on most cell surfaces. This peptide was masked with a caging group, rendering it biologically inert. Illumination with UV light released the caging group from the YIGSR, allowing binding to cells.
The Role of Educational Level in Glycemic Control among Patients with Type II Diabetes Mellitus

Field: Medicine (Health Sciences)

The proportion of patients with poor glycemic control was high in this study. This study showed that educational level may not be a good predictor of better therapeutic compliance. In-spite of the significant importance of appropriate diet and exercise in the control of diabetes, there was a high rate of poor adherence to diet and to exercise, especially among females. Educational programs that emphasize adherence to treatment regimens as a whole, especially to diet, to exercise and to regular follow up are of greater benefit in glycemic control as compared to compliance of medications alone.
Hordeum vulgare L. convar. vulgare var. hybernum Viborg, HOR 544

Field: Agricultural and Biological Sciences (Life Sciences)

PGRFA accession of IPK Gatersleben Plant Genetic Resource Taxon: Hordeum vulgare L. convar. vulgare var. hybernum Viborg Accession number: HOR 544 Conserved by: DEU146 Acquisition: 1946 Origin country: TUR Biological status: Traditional cultivar/landrace MLS status: Included AEGIS status: Included Historic: No
LHD ICH-ICE2 #172812.1

Field: Physics and Astronomy (Physical Sciences)

High-frequency Magnetic Probe to measure high-frequency waves, e.g. waves excited by ICRF antennas or waves excited by high-energy particles. Probe head is one-turn loop with Faraday shield. Two loops are paired with different turn direction. Frequency range: approximately 10 kHz - 1 GHz. Loop size: 15 cm x 15 cm.
Pharmacological Bases for the Use of Dopamine and Related Drugs in the Treatment of Congestive Heart Failure

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The purpose of this paper is to review the pharmacological background of the use of dopamine (DA), DA agonists, and DA prodrugs in the treatment of congestive heart failure (CHF). Studies leading to the use of DA and methods utilized to investigate new DA agonists are reviewed. Finally, preclinical and clinical data of DA agonists and prodrugs are evaluated to estimate current and future roles of DA, DA agonists, and DA prodrugs in the treatment of congestive heart failure.
Interactions of Metal Ions with Polynucleotides and Related Compounds. VII. The Binding of Copper(II) to Nucleosides, Nucleotides, and Deoxyribonucleic Acids*

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTInteractions of Metal Ions with Polynucleotides and Related Compounds. VII. The Binding of Copper(II) to Nucleosides, Nucleotides, and Deoxyribonucleic Acids*Gunther L. Eichhorn, Patricia Clark, and Edwin D. BeckerCite this: Biochemistry 1966, 5, 1, 245–253Publication Date (Print):January 1, 1966Publication History Published online1 May 2002Published inissue 1 January 1966https://pubs.acs.org/doi/10.1021/bi00865a032https://doi.org/10.1021/bi00865a032research-articleACS PublicationsRequest reuse permissionsArticle Views317Altmetric-Citations108LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
In Vitro Replication of Human Norovirus

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Human norovirus (HuNoV) infection is a major cause of gastroenteritis all over the world. Despite this, these non-enveloped RNA viruses are poorly characterized due to the lack of robust and widely available HuNoV culture systems. The two published systems (B cell line and stem cell-derived enteroids) support replication of HuNoVs but the levels of replication are not sufficient for the generation of highly purified virus stocks or the development of culture-based quantification assays. Therefore, improvement of HuNoV in vitro replication is still needed. Murine norovirus and other caliciviruses have provided insights into norovirus replication that paved the way for the development of the current HuNoV culture systems and may also aid in the improvement of these systems. This review will highlight ways in which previous research guided and impacted the development of HuNoV culture systems and discuss ways in which more recent discoveries might be utilized to improve the quality of the HuNoV in vitro replication.
PERAN PENGADILAN HUBUNGAN INDUSTRIAL PADA PENGADILAN NEGERI PADANG KELAS IA DALAM MEMBERIKAN KEPASTIAN HUKUM TERHADAP PERKARA PEMUTUSAN HUBUNGAN KERJA

Field: Social Sciences (Social Sciences)

After the enactment of Law No. 2 of 2004 on Industrial Relations Dispute Settlement, the implication of handling disputes disputes becomes the authority of the Industrial Relations Court at the local District Court. In addition to the court (litigation) settlement disputes termination disputes may also be settled out of court (non litigation). The Industrial Relations Court at the IA District Court handled several termination matters. In this study the authors will focus on the settlement through the judiciary (litigation). The problems discussed in this paper is the Role of Industrial Relations Court in Providing Legal Certainty to Termination of Employment Case (PHK) and Implementation of Decision. This study is juridical normative. Based on this research the authors draw the conclusion that the Industrial Relations Court has not played a role in Giving Legal Certainty to Termination Employment Case. The Industrial Relations Court only performs its role in accordance with applicable law. Implementation of the PHI's decision that the losing party tended to file a cassation appeal. Parties that have not / do not want to implement the contents of the decision of the IRC are caused by the absence of sanctions in Law Number 13 Year 2003 concerning Manpower and Law Number 2 Year 2004 on Industrial Relations Dispute Settlement.