jimnoneill/paper-to-field-training huggingface dataset:
&#x00B5; Analysis for Robust Blood Glucose Regulation in T1DM Patients

Field: Engineering (Physical Sciences)

The idea of an integrated system called Artificial Pancreas (AP) has become a research area for multiple disciplines such as biomedical and automatic control. The AP gives a promising approach for the Type 1 Diabetes Mellitus (T1DM) treatment since an automatic insulin infusion device is expected. This system consists of three parts: control algorithm, insulin pump and glucose sensor. Scientific community has treated these elements separately and some agree that the most challenging part is related to the control algorithm. Initial proposals for this algorithm have appeared, based on classical and well-known control techniques. Nevertheless, the aim of this AP is to reduce disease complications despite variability of internal/external body conditions. From a control point of view this variability can be treated as perturbations or parametric uncertainties. Therefore, robust control techniques should be applied in order to propose more realistic approaches. A sensitivity analysis [18] performed on Sorensen nonlinear model was able to identify three parameters as the most responsible for changes in blood glucose and insulin dynamics. Previous work have suggested unstructured uncertainties on these parameters and proposed H8 control algorithms as the case of Ruiz-Velázquez et. al. [20] and Femat et. al. [21]. In the present paper the same uncertain parameters are structured in the linearized Sorensen model in such a manner μ-analysis is applied. Thus, the aim of this analysis is to verify if robust stability and robust performance are preserved when the H8 control algorithms were designed on a different scenario. The results attempt to justify the use structured uncertainties in a T1DM patient model as a more appropriate approach. This work can be considered as a preliminary in development of new control algorithms for blood glucose regulation based on the μ-synthesis technique.
Antibody drug conjugates in recurrent or metastatic cervical cancer: a focus on tisotumab vedotin state of art

Field: Medicine (Health Sciences)

Cervical cancer (CC) is still characterized by a poor prognosis despite the progress made in its treatment in recent years. Although immunotherapy has improved outcomes for advanced/recurrent disease, there is a significant gap in addressing patients’ needs when they progress after platinum and immunotherapy treatments. In this setting, traditional chemotherapy showed limited effectiveness. In this context, antibody–drug conjugates (ADCs) emerged as a promising tool within targeted cancer therapies. Tisotumab vedotin (TV), an ADC targeting tissue factor, represents the first ADC approved by the US Food and Drug Administration for the treatment of recurrent or metastatic CC with disease progression on or after chemotherapy. In phase I–III published trials, TV has already demonstrated an advantage in terms of objective response rate (17.8%–54.4%) and progression-free survival (3.1–6.9 months) in patients who progressed to the first-line standard therapy. Data concerning the addition of TV to platinum/pembrolizumab first-line chemotherapy are still under analysis and strongly expected. However, several questions are still unresolved: (1) the identification of the most suitable timing for ADCs administration in the treatment sequence of advanced/recurrent CC; (2) the evaluation of combination therapies as a tool to minimize the emergence of resistant clones and to enhance overall effectiveness; and (3) the assessment of tolerability and correct management of special toxicities (e.g. ocular and neurological adverse events). In the near future, an improvement in patient selection via biomarker-driven strategies should be crucial for optimizing both treatment benefits and maintaining an acceptable toxicity profile.
Stratifikasi Sosial dalam Budaya A’matoang Masyarakat Turatea Kabupaten Jeneponto

Field: Social Sciences (Social Sciences)

This study aims to describe the culture of A'matoang and the form of social stratification in A'matoang Culture of Turatea people of Jeneponto Regency. Technique of taking informant which used in this research is Purposive sampling based on criterion which have been determined by researcher. Number of informants as many as 15 people aged 25-60 years. Data collection techniques used observation, interview, documentation and participatory methods. The result of the research shows that: (1) A'matoang culture is a series of marriage process, has meaning giving or giving in the form of goods such as clothes, sarong, songkok and veil to mother-in-law to the father-in-law of the men. (2) The form of social stratification in A'matoang cultures of society includes the large number and luxury of pa'matoang which means high social status, whether it is measured from the wealth possessed or from the nobility or karaeng lineage.Keywords: Stratification, Culture, A'matoang
Crowdfunding and Economic Growth : Potential Effects on Investment Efficiency

Field: Economics, Econometrics and Finance (Social Sciences)

Crowdfunding is an alternative form of finance that have emerged with the widespread adoption of the internet. With the increasing utilization of crowdfunding, this thesis sets out to theoretically investigate whether crowdfunding could affect economic growth. If the choice of investment allocation mechanism could have any effect on the efficiency of investments made in the economy. The results show that crowdfunding could have a potential effect on the leakage of investments in the economy. The relative accuracy of the screening process and the transaction costs coupled with the method used for conducting the investments could affect the socially optimal proportion of investments conducted using crowdfunding.
A Self-Adapting Task Scheduling Algorithm for Container Cloud Using Learning Automata

Field: Computer Science (Physical Sciences)

With the rapid development of cloud computing and container technology, more and more applications are deployed to the cloud, and the scale of cloud platform is expanding. Due to the large number of container instances running in the platform, complex dependency relationship, fast version iteration and other characteristics, the update of business can often cause the change of the whole cloud resource environment, which triggers the repetitive scheduling problem of related tasks and affects stability of the business. In this paper, we propose a self-adapting task scheduling algorithm (ADATSA) using learning automata to solve these problems. Firstly, we design a learning automata model and objective function for the system on task scheduling problem. Then, we realize an effective reward-penalty mechanism for scheduling actions in combination with the idle state of resources and the running state of tasks in the current environment. Meanwhile, the environment is modeled by cluster, node and task, and the probability of action selected is optimized by scheduling execution, thus enhancing the adaptability to the cloud environment of the scheduling and accelerating convergence. Finally, we construct a framework of task load monitoring with buffer queue to achieve dynamic scheduling based on priority. The experimental part verifies the effectiveness of proposed algorithm with different angles such as resource imbalance degree, resource residual degree and QoS. Compared with other learning automata scheduling models such as LAEAS, non-automata technology based algorithms such as PSOS and K8S scheduling engine, ADATSA shows the better performance of environment adaptability, resource optimization efficiency and QoS in dynamic scheduling. The theoretical analysis was consistent with the experimental results.
Development of an Index to Measure the Conservation Behaviour of Farmers

Field: Agricultural and Biological Sciences (Life Sciences)

Meeting the demand of rising population and sustaining the quality of the environment are the two major challenges of Indian agriculture system. The conservation practices have the potential to achieve food security while also have the capacity to retain the environmental sustainability. This article was focussed with the construction of an index to assess the adoption of conservation practices by farmers. Based on the review of literature and discussion with the expert's, indicators and sub-indicators were identified and enlisted. Relevancy test method was followed in the construction of an index. The list of sub-indicators was sent to 75 experts with the request, to critically evaluate each sub-indicator for its relevancy to be included in the Conservation Behaviour Index (CBI). Out of 75 experts, 30 experts responded in time and at the earliest. The criteria to be followed in this procedure was sub-indicators having relevancy percentage above 75, relevancy weightage above 0.75 and mean relevancy score above 2.25 was considered for inclusion in Conservation Behaviour Index. Based on the above three criteria 56 sub-indicators were retained. Further the index has been administered in the study area and the scores obtained were analysed using cumulative frequency method to classify farmers into three categories.
Impact of social media addiction on physical and mental health in medical and paramedical undergraduate students of Jamnagar urban area: A cross-sectional analytical study

Field: Health Professions (Health Sciences)

Background: Sixty-three percent of the world population uses the Internet and 58% use social media. Internet addiction or social media addiction is an impulse disorder marked by excessive or poorly regulated pre-occupations, desires, or behaviors. Teenagers and young age students are more prone to social media addiction as they spend more time on smartphones. Aims and Objectives: The present study was conducted to detect social media addiction and its impact on the physical and mental health of students. Materials and Methods: The study was done in four medical and paramedical colleges with 720 students divided equally in all four colleges and further in each year. A novel social media addiction scale was used for derived from Young’s Internet addiction scale to assess social media addiction. Data were collected in the GitHub tool. A Chi-square test and univariate logistic regression were used to analyze the data. Results: 37.5% of the study participants were social media addicted. Medical students were more addicted as compared to paramedical. Physical and mental health problems were seen more in social media addicts as compared to non-addicts. Behavioral changes were seen more in social media addicts. Conclusion: There is a high prevalence of social media addiction in medical and paramedical students. Proper steps need to be taken to counteract this growing problem at an early stage.
Sub-Tg relaxation in hydrous soda-lime-silicate and sodium-borosilicate glasses

Field: Chemistry (Physical Sciences)

Water plays an important role for the depolymerization of silicate glasses which becomes noticeable by a distinct decrease of glass transformation temperature, Tg. Thus, it has a considerable influence on aging and fatigue as well as on sub-critical crack growth in glasses. In this connection also sub-Tg relaxation processes play a major role, but they are poorly investigated in glasses with high contents of structural bonded water. Therefore, soda-lime-silicate and sodium-borosilicate glasses with water contents up to 5 wt.% H2O were investigated by differential thermal analysis and sphere penetration viscometry, as well as internal friction measurements. The latter was applied to study network related relaxation mechanisms (α-relaxation) in the range of glass transition, as well as faster relaxation modes occurring at lower temperatures (β-, γ- relaxation). Total water content and concentrations of H2O molecules (CH2O) and OH groups (COH) in the glasses were determined by infrared spectroscopy.
For low water contents two sub-Tg internal friction peaks were observed and assigned to the low-temperature motion of alkali ions (γ-relaxation) and cooperative movements of dissimilar mobile species under participation of OH at higher temperature (βOH relaxation).
For large water contents, where significant amounts of molecular water are evident, a low temperature shoulder appears on the β-relaxation peak. This emerging relaxation mode (βH2O relaxation) was assigned to the motions of H2O molecules.
[Dynamics of rat hepatocyte histone glycoxidation after general x-ray irradiation].

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Dynamics of structural parameters of hepatocyte histone glucoxidative modification 3, 9 and 24 h after general X-ray irradiation of rats at dose 5 Gy was studied. Dynamics of these parameters (content of carbonyl groups, bityrosyl cross-linkings, pentosidines, advanced glycation end products) was compared with alterations in DNA structure (according to agarose gel electrophoresis) and lipid peroxidation extent (by malondialdehyde content). Oxidative stress induced by hepatocyte irradiation results in structural damage of DNA and histones accompanied by an increase of histone bityrosyl cross-linking and carbonyl content. The content of advanced glycation end products in histones corresponds to the extent to DNA damage and malondialdehyde content. The described postradiation modifications of histones may be important for regulation of chromatin function.
The ethnic tourism expansion cycle: The case of Yunnan province, China

Field: Social Sciences (Social Sciences)

There is an ever-growing body of literature suggesting that the Butler's Tourist Area Life Cycle (TALC) model may be a very useful conceptual tool for understanding the development patterns of mass tourism destinations. However, some authors have reported that the TALC model shows limitations in regions like the Asia Pacific and when applied to the development of alternative forms of tourism, such as ethnic tourism. Therefore, the purpose of this paper was to examine whether selected ethnic tourism destinations in Yunnan province in the People's Republic of China exhibited characteristics consistent with the stages of Butler's TALC model. The findings revealed that Butler's TALC model might be useful in understanding the development of individual ethnic tourism destinations in Yunnan province. However, the findings also revealed that the characteristics of the host culture might influence the way the destination develops and that each destination's cycle of development is influenced significantly by the development of neighboring destinations.
Trust and the governance of international strategic alliances

Field: Business, Management and Accounting (Social Sciences)

The aim of this study is to deepen our understanding of the choice of governance mode in international strategic alliances (ISAs) by examining the relationships between opportunism, trust and equity versus on-equity-based governance of ISAs. Previous studies provide ambiguous results regarding the linkages between opportunism, trust and governance form. To resolve this ambiguity, we identify the separate influences of the relational attributes of the partners, host country macro environmental attributes and characteristics of ISA transactional activities on governance choice in ISAs. Empirical estimation using primary data on international strategic alliances involving Danish firms indicate a particularly strong relationship between attributes of alliance partners and ISA governance mode. Specifically, trustworthiness appears to be a substitute for administrative control. In addition, we find attributes of “host country «governance to be relevant to the choice of ISA governance mode, although relational attributes seem far more important
Use of the free jejunal loop to replace cervical oesophagus in an experiment.

Field: Medicine (Health Sciences)

The paper presents the results of experimental studies exploring the possibility to replace the cervical oesophagus with a free intestinal loop. The experiments were carried out in dogs and cervical oesophagus replacement was performed using a jejunal loop. Nutrition was provided by mesenteric vessels anastomosed by means of a microsurgical operative technique. The intestinal segment was subsequently used to replace the resected segment of the cervical oesophagus. The results of our experiments indicate this new operative technique can be used in clinical practice.
An angina diagnostic system using fuzzy clustering and correlation

Field: Computer Science (Physical Sciences)

In this paper, we present a signal processing method capable of detecting angina in electrocardiograms. The adopted procedure is based on fuzzy clustering to reduce the amount of data sampling and a comparison with samples from a previously established database. By using the correlation method on the samples, it is possible to establish an initial indication of angina. The reduced number of samples of the clustering process turns the processing simpler and allows its hardware implementation. According to the tests conducted, the method achieves 85% correct diagnoses.
Legal Politics in the Implementation of Regional Autonomy

Field: Social Sciences (Social Sciences)

The 1945 Constitution is the highest law in Indonesia. From 1999 to 2002, the MPR underwent four stages of change which were carried out democratically, constitutionally and institutionally. Arrangements that have undergone changes include Article 18 concerning arrangements for the administration of regional government. The implementation of the provisions of Article 18 of the 1945 Republic of Indonesia Constitution is currently carried out by Law Number 23 of 2014 concerning Regional Government as the basis for political reference for regional autonomy law in Indonesia. The problems in this study are how is the implementation of regional autonomy in Indonesia, what is the impact of regional autonomy on the development of Indonesia's regions, and how are changes in the culture of society in the implementation of regional autonomy in Indonesia. The conclusion that can be drawn from these results is that the implementation of regional autonomy in Indonesia must have a sense of confidence from the central government, local government and the community, with decentralization which is expected to optimize community pre- cons, the impact of regional autonomy opens up opportunities to implement wide-open economic democracy, and so that it can advance the people's economy, as a result of the reform euphoria that can lead to counter-productivity. This must become a productive and constructive culture and behavior to realize healthy and balanced regional autonomy.
Ehrharta ramosa subsp. aphylla (BOL218814)

Field: Agricultural and Biological Sciences (Life Sciences)

Kingdom: Plantae
Division: Magnoliophyta
Class: Monocots
Order: Poales
Family: Poaceae
Scientific name: Ehrharta ramosa subsp. aphylla (Schrad.) Gibbs Russ.
Specimen barcode: BOL218814
Finding focus in a difficult landscape: Therapists’ experiences with challenging video guidance processes for parent–infant dyads

Field: Psychology (Social Sciences)

ABSTRACT Marte Meo video guidance uses filmed interaction of the actual parent–infant dyad in the guidance of caregivers. Exploring the challenges that therapists meet in the guidance of parent–infant dyads may illuminate important aspects of the method itself as well as the therapists’ role and requirements. This could lead to method development and improved practice, but is hitherto little addressed. In this paper, we explore how skilled therapists experience and handle challenging or failing guidance processes with parent–infant dyads. We analyzed interviews with 13 Marte Meo therapists/supervisors using team‐based reflexive thematic analysis. Four main themes were identified: promoting relational growth in a coercive context, building an alliance that feels safe for the parents, looking at positive moments in difficult lives, and handling intense feelings as a therapist. Our findings show that therapists experience specific therapeutic and ethical challenges with a vulnerable subgroup of parent–infant dyads where child protective issues arise, where caregivers’ insecurities impede the therapeutic relationship, and where caregivers have unsolved relational or mental health problems. The therapists’ role becomes pivotal and demanding with regard to the therapeutic alliance, the therapeutic interventions in the guidance process, and their own need for regulation, supervision, and structure. Identification of these vulnerable dyads early in the process could facilitate a better adaptation and practice of video guidance. Our findings suggest a need for supporting structures, clinical supervision, and training that address these challenges.
two of our basic products make three of the best pentaerythritols you can buy.

Field: Chemical Engineering (Physical Sciences)

RETURN TO ISSUEPREVAdvertisementNEXTtwo of our basic products make three of the best pentaerythritols you can buy.Cite this: Chem. Eng. News 1967, 45, 12, 40Publication Date (Print):March 13, 1967Publication History Published online6 November 2010Published inissue 13 March 1967https://doi.org/10.1021/cen-v045n012.p040Copyright © 1967 AMERICAN CHEMICAL SOCIETYArticle Views63Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (88 KB) Get e-Alerts
Family History of Hypertension and Red Cell Cation Transport in High School Students

Field: Medicine (Health Sciences)

High school students who had at least one parent with hypertension (n = 22) were compared to schoolmates of the same age with a negative family history of hypertension in the parents (n = 21). We investigated in both groups the maximal rate of the ouabain-sensitive Na pump and the Na-K cotransport in nystatin-loaded cells and the Lii-Nao countertransport in lithium-loaded cells. The two groups were significantly different only in the sum of net Na transport mediated by the Na-K pump and Na-K cotransport. The mean diastolic blood pressure in the positive family history group was significantly higher. With control for blood pressure the difference in the maximal rate of Na transport was no longer significant; it remains uncertain if control for blood pressure represents "over-adjustment'. The finding of a higher maximal rate of Na transport in these adolescents who are at increased risk of future hypertension, yet currently well within the normal range, suggests that abnormal sodium metabolism may be a useful marker and appears early in the pathogenesis of this disease.