jimnoneill/paper-to-field-training huggingface dataset:
The Pertinent Role of HSV and CMV in Sudanese Esophageal Cancer Epidemiology

Field: Medicine (Health Sciences)

Background: Viruses may play a role in the development of esophageal cancer (EC), although this is not yet known with certainty. This study, which examines Sudanese individuals with esophageal tumors, seeks to identify the involvement of cytomegalovirus (CMV) and herpes simplex virus (HSV) in the development of esophageal cancer. Materials and methods: This study looked back at 61 blocks of formalin-fixed, paraffin-embedded (FFPE) tissue that had already been identified as esophageal cancers. It used immunohistochemical staining to find herpes simplex virus type 1 and cytomegalovirus. Data were obtained from histopathology laboratories at the National Health Laboratory (NHL) and Soba University Hospital between January 2017 and January 2020. Positive results were confirmed with the polymerase chain reaction (PCR) technique. Results: Of the 61 FFPE blocks analyzed, 35 (57.4%) belonged to men. The bulk of participants (54.1%) were older than 60 years old. The most prevalent tumor type was squamous cell carcinoma (SCC), which accounted for 75.4% of cases. 16.4% of participants, equally divided between males and females, tested positive for HSV. 70% of HSV positive results came from people over the age of 60, and all of them were in SCC cases. Males accounted for 57% of the positive results. Individuals over the age of 60 were responsible for 80% of positive CMV results, while SCC cases accounted for 85%. All the PCR results were negative. Conclusion: These results imply a link between HSV, CMV, and esophageal cancer. We need more research with a larger sample size to understand how these viruses cause esophageal cancer.
Fast-fashion faux pas

Field: Business, Management and Accounting (Social Sciences)

Purpose This paper aims to review the latest management developments across the globe and pinpoint practical implications from cutting-edge research and case studies. Design/methodology/approach This briefing is prepared by an independent writer who adds their own impartial comments and places the articles in context. Findings Fast fashion is incredibly damaging to the environment. Sustainable initiatives are key to both the survival of fast fashion brands as well as the reduction of environmental damage caused by the fashion industry. Originality/value The briefing saves busy executives, strategists and researchers hours of reading time by selecting only the very best, most pertinent information and presenting it in a condensed and easy-to-digest format.
Photon Wave Mechanics

Field: Physics and Astronomy (Physical Sciences)

In contrast to wave functions in nonrelativistic quantum mechanics interpreted as probability amplitudes, wave functions in relativistic quantum mechanics have generalized meanings such as charge-density amplitudes, energy-density amplitudes as well as particle-number density amplitudes, etc. Applying electromagnetic field intensities we construct a photon wave function, it corresponds to the (1,0)+(0,1) spinor representation of the electromagnetic field, and can be interpreted as the energy-density amplitude of photons outside a source. In terms of photon wave functions we develop photon wave mechanics, which provides us with a new quantum-mechanical description for photons outside a source.
Smoking and response to rituximab in rheumatoid arthritis: results from an international European collaboration

Field: Medicine (Health Sciences)

Objectives: To investigate whether smoking habits predict response to rituximab (RTX) in rheumatoid arthritis (RA). Method: We included patients from the CERERRA international cohort receiving the first treatment cycle with available smoking status (n = 2481, smokers n = 528, non-current smokers n = 1953) and at least one follow-up visit. Outcome measures were change in Disease Activity Score based on 28-joint count (ΔDAS28) and European League Against Rheumatism (EULAR) good response at 6 months, with non-current smokers as the referent group. Results: Compared with non-smokers at baseline, smokers were more often rheumatoid factor (RF)/anti-citrullinated protein antibody (ACPA) positive and males, had shorter disease duration, lower DAS28 and Health Assessment Questionnaire (HAQ) score, a higher number of prior biological disease-modifying anti-rheumatic drugs, and were more likely to receive concomitant conventional synthetic disease-modifying anti-rheumatic drug (csDMARDs). Disease activity had decreased less in smokers at 6 months (ΔDAS28 = 1.5 vs 1.7, p = 0.006), although the difference was no longer significant after correction for baseline DAS28 (p = 0.41). EULAR good response rates did not differ between smokers and non-smokers overall or stratified by RF/ACPA status, although smokers had lower good response rates among seronegative patients (ACPA-negative: 6% vs 14%, RF-negative: 11% vs 18%). Smoking did not predict good response [odds ratio (OR) = 1.04, 95% confidence interval (CI) = 0.76–1.41], while ACPA, DAS28, HAQ, and concomitant csDMARDs were significant predictors for good response. However, when stratified by country, smokers were less likely to achieve good response in Sweden (unadjusted OR = 0.24, 95% CI = 0.07–0.89), and a trend was seen in the Czech Republic (OR = 0.45, 95% CI = 0.16–1.02). Conclusion: In this large, observational, multinational RA cohort, smokers starting RTX differed from non-smokers by having shorter disease duration and lower disease activity, but more previous treatments. The overall results do not support smoking as an important predictor for response to RTX in patients with RA.
MRSA colonization in health care professionals with varying degrees of exposure to the hospital environment and its susceptibility to mupirocin in a tertiary care centre

Field: Medicine (Health Sciences)

Methicillin-resistant (MRSA) is one of the major causes of healthcare associated infections with significant morbidity and mortality. Health care workers act as a carrier in spread of MRSA in hospitals. Use of Mupirocin to eradicate the carrier state is the need of the hour. : This study was undertaken to assess the prevalence of MRSA colonization among health care workers with varying degree of exposure to hospital environment and to know the susceptibility of Mupirocin to MRSA. : Swabs were collected from anterior nares and finger web spaces of 100 health care workers (HCWs). The specimens were processed and colonies of were identified by standard methods. The strains of MRSA were identified by using Cefoxitin (30µg) disk on Muller Hinton agar. The MRSA isolates were then tested for Mupirocin susceptibility. In the present study, 100 nasal and inter digital spaces swabs yielded 15 and 10 MRSA strains respectively. Among the 100 HCWs screened, the majority of MRSA colonization was seen in HCWs with a history of exposure to hospital environment for around 5-10 years or more. All 30 with 15 MRSA strains isolated was sensitive to both 5µg and 200µg Mupirocin disc by Kirby-Bauer disc diffusion method. The high rate of Nasal MRSA carriage among health care workers is alarming. HCWs with long duration of exposure to hospital environment were more colonized with MRSA. More awareness and training sessions on the importance of MRSA and hand hygiene measures to be implemented to prevent MRSA transmission from HCWs to vulnerable patients. We suggest that MRSA screening should be performed for all HCWs and detection of susceptibility of Mupirocin will result in appropriate use of this antibiotic in decolonization.
Implementing an Evidence Based Practice Guideline to Standardize the Care of Adults with Type 2 Diabetes

Field: Health Professions (Health Sciences)

PURPOSE: The purpose of this quality improvement project was to explore the impact of implementing the Health TeamWorks practice guideline in standardizing the care for adults with type 2 diabetes. The goal was to improve patients’ glycosylated hemoglobin A1c (HbA1c) levels to less than 8% and Low Density Lipoprotein (LDL) levels to less than 100mg/dL. The Implementation Model, adapted by Titler (2010) and built on Rogers Diffusion of Innovation Theory (Rogers, 2003), guided this project. Interventions used to promote the use of guideline included the use of opinion leaders, education classes, audit and feedback of performance during providers’ meetings. METHODS: A ‘pre and post’ implementation evaluation of patients’ laboratory results was the design used to gather data. Patients with uncontrolled HbA1c levels were checked every three months and LDL levels once during the year of project. RESULTS: The convenience sample of 11 providers included six medical doctors and five nurse practitioners employed at Kalihi Pālama Health Center. They were primary care providers of record for 88 patients with diabetes whose laboratory results were tracked for this project. Descriptive and trend analyses revealed the 3-months, 6-months, 9-months and 12-months checks results of 74%, 32%, 52% and 43% of patients with improved HbA1c levels, respectively. Of the 88 patients, 19% met the target of HbA1c level of less than 8% at least once during the project year. Forty three patients had their LDL levels rechecked in 2015 and 33% of them met the target goal of less 100 mg/dL. DISCUSSION. The results revealed a decrease in HbA1c in the majority of patients; however, glycemic relapse was noted at the 6-months checkpoint. Despite the work of care coordinators, the patient ‘no show’ for appointments was a common occurrence due to a lack of insurance and financial resources. Providers identified facilitators and barriers to using the guideline. It was difficult to establish adherence of providers’ use of the guideline because of the multiple ‘patient factors’ identified that prevented consistent implementation and evaluation. However, working in a collaborative team made a difference in bridging the gaps in the care of diabetic patients.
Resurgence of common respiratory viruses and mycoplasma pneumoniae in children after ending the zero-COVID policy, Shanghai, China, 2023

Field: Medicine (Health Sciences)

Abstract

Background China has adhered to policies of zero-COVID for almost three years since the outbreak of COVID-19, which have remarkably affected the circulation of respiratory pathogens. However, China has begun to end the zero-COVID policies in late 2022. Here, we reported a resurgence of common respiratory viruses and mycoplasma pneumoniae with unique epidemiological characteristics among children after ending the zero-COVID policy in Shanghai, China, 2023. Methods Children hospitalized with acute respiratory tract infections were enrolled from January 2022 to December 2023. Nine common respiratory viruses and 2 atypical bacteria were detected in respiratory specimens from the enrolled patients using a multiplex PCR-based assay. The data were analyzed and compared between the periods before (2022) and after (2023) ending the zero-COVID policies. Results A total of 8550 patients were enrolled, including 6170 patients in 2023 and 2380 patients in 2022. Rhinovirus (14.2%) was the dominant pathogen in 2022, however, Mycoplasma pneumoniae (38.8%) was the dominant pathogen in 2023. Compared with 2022, the detection rates of pathogens were significantly increased in 2023 (72.9% vs. 41.8%, p < 0.001). An out-of-season epidemic of respiratory syncytial virus was observed during the spring and summer of 2023. The median age of children infected with respiratory viruses in 2023 was significantly greater than that in 2022. Besides, mixed infections were more frequent in 2023 (23.8% vs. 28.9%, p < 0.001). Conclusions China is now facing multiple respiratory pathogen epidemics with changing seasonality, altered age distribution, and increasing mixed infection rates among children in 2023. Our finding highlights the need for public health interventions to prepare for the respiratory pathogen outbreaks in the post-COVID-19 era.
Analisis Pemahaman Organisasi Keagamaan UKM-KP dan UKM-K FMIPA Mahasiswa dalam menerapkan Nilai-Nilai Pancasila di Lingkungan Kampus Universitas Negeri Medan

Field: Social Sciences (Social Sciences)

Pancasila as the ideology and basis of the state plays an important role in shaping the character of students at Medan State University. Through Student Activity Units (UKM), such as UKM-KP and UKM-K FMIPA, Pancasila values are internalized through various social, religious and scientific activities. This research uses qualitative methods with interviews, direct observation and documentation, which are analyzed thematically with source triangulation to ensure data validity. The research results show that activities such as mass, group prayer, social visits, live-ins, democratic deliberations, and social programs play an effective role in instilling the values of Divinity, Humanity, Unity, Democracy, and Social Justice. These findings emphasize the importance of UKM as a forum for developing Pancasila character which is reflected in campus and community life.
Teaching Youth Media: A Critical Guide to Literacy, Video

Field: Arts and Humanities (Social Sciences)

It is a distinctly postmodern impulse to trouble accep-ted notions about what it means to be a reader and writer. And in so doing, the authors and contributors of the two volumes under review demonstrate just how complex the business of literacy teaching and learning really is. As the theories and contexts for our work have expanded well beyond understandings of reading and writing processes, we have found it intellectually excit-ing and socially and politically honest to foreground what has heretofore been left in the shadows, namely that any act of literacy is rife with issues of history, cul-ture, class, politics, and identity. If reading is fundamen-tally a process of reading the world then a multitude of semiotic, audio, visual, and electronic data streams need to be accounted for in our studies of literacy. A preservice teacher presented in the Alvermann volume puts it this way: “If you are deriving a message from it, you are reading it ” (p. 73). In Alvermann, we are asked to rethink the authority of the printed word as an insidious tool of marginaliza-tion (King &amp; O’Brien). At the same time, we are urged to expand our view of literacy to include such practices as Knobel and Lankshear’s scenariating (asking “what
POSSIBILITY OF HEREDITARY TRANSMISSION OF YELLOW FEVER VIRUS BY AEDES AEGYPTI (LINN.)

Field: Immunology and Microbiology (Life Sciences)

Attempts to obtain passage of yellow fever virus from one generation to the next in A. aegypti were unsuccessful. Subcutaneous injections at varying intervals of a saline emulsion of 200 eggs laid by an infective lot of mosquitoes produced no reaction in six normal M. rhesus monkeys. Negative results were also obtained in five biting and two injection experiments with progeny of the same infective lot of mosquitoes in which seven normal monkeys were used. The eggs consisted of batches laid after the first, second and fourth blood-meals of the original lot; the latter feeding occurred 41 days after the initial infecting meal. The imaginal offspring represented rearings following the first, second and fifth blood-meals of the parent lot. The last feeding occurred 54 days after the first. It is concluded that under the conditions of the experiments here reported hereditary transmission of yellow fever by A. aegypti is improbable. Variations in age and in number of blood-meals of parent and offspring mosquitoes had no effect in achieving passage of the virus from one stage of the insect to another.
Outcomes of peptide receptor radionuclide therapy (PRRT) in metastatic grade 3 neuroendocrine tumors (NETs).

Field: Medicine (Health Sciences)

e15694 Background:Grade 3 (G3) NETs have a poor prognosis and limited treatment options (usually chemotherapy). PRRT is a potential treatment option if all sites of disease demonstrate high uptake on somatostatin-receptor imaging (SSRI). We retrospectively evaluated the efficacy of PRRT in G3 NETs. Methods: We reviewed records of patients with metastatic G3 NETs (Ki-67 > 20%) who received PRRT at our institution. Patients were treated with up to 5 cycles of PRRT, predominantly 177 Lu-DOTA-octreotate. Further maintenance PRRT was administered upon progression if deemed suitable on SSRI. Radio-sensitizing chemotherapy was administered unless contra-indicated. Kaplan-Meier estimate was used to determine median overall survival (OS) and median time to new treatment/death (TNTD) defined from start of PRRT. Subgroup-analysis was performed for patients with Ki67 < 55% and ≥55%. Results: 26 patients with metastatic G3 NET received PRRT; 22 combined with chemotherapy (capecitabine/temozolomide (n = 12), 5-fluorouracil or capecitabine (n = 8), other (n = 2)). 58% were male. The median age was 62 (range 16-78 years). 61% had pancreatic NET, 19% small bowel, 8% lung, 8% unknown primary, 4% rectal. 77% had received at least one line of prior chemotherapy. 54% received prior platinum-based chemotherapy. Median follow-up was 33 months (range 8-83 months). Patients received a median of 4 cycles of PRRT (range 1-15). The estimated median OS from start of PRRT was 18 months: for Ki-67 < 55% (n = 21), 20 months; and Ki-67≥ 55% (n = 5), 9 months. The estimated median TNTD was 12 months: for Ki-67 < 55%, 16 months; and Ki-67≥55%, 4 months. 31% of patients were alive without a change in treatment modality following PRRT. Conclusions: In thispoor prognosis G3 NET cohort of whom 77% had received prior chemotherapy, a median OS of 18 months from start of PRRT is encouraging and warrants further study. PRRT is a promising treatment option for patients with G3 NET with high somatostatin-receptor expression selected by SSRI.
Consciousness, Backward Coreference, and Logophoricity

Field: Arts and Humanities (Social Sciences)

July 01 2004 Consciousness, Backward Coreference, and Logophoricity In Special Collection: CogNet Seth A. Minkoff Seth A. Minkoff University of Massachusetts—Boston Search for other works by this author on: This Site Google Scholar Author and Article Information Seth A. Minkoff University of Massachusetts—Boston Online ISSN: 1530-9150 Print ISSN: 0024-3892 © 2004 Massachusetts Institute of Technology2004 Linguistic Inquiry (2004) 35 (3): 485–494. https://doi.org/10.1162/ling.2004.35.3.485 Cite Icon Cite Permissions Share Icon Share Facebook Twitter LinkedIn MailTo Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Search Site Citation Seth A. Minkoff; Consciousness, Backward Coreference, and Logophoricity. Linguistic Inquiry 2004; 35 (3): 485–494. doi: https://doi.org/10.1162/ling.2004.35.3.485 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsLinguistic Inquiry Search Advanced Search This content is only available as a PDF. © 2004 Massachusetts Institute of Technology2004 Article PDF first page preview Close Modal You do not currently have access to this content.
Potential use ofMucor circinelloidesfor the biological control of certain helminths affecting livestock reared in a care farm

Field: Agricultural and Biological Sciences (Life Sciences)

A preliminary study to evaluate the possibilities of biological control procedures against parasites affecting livestock reared in a care farm has been conducted. Adults with mental disabilities were involved in spreading the spores of the filamentous fungus Mucor circinelloides directly onto the faeces, or as a food additive. In the first assay, the spores were sprayed directly onto the faeces of piglets and calves parasitised by roundworms (Ascaris suum) and liver flukes (Fasciola hepatica), respectively. In the second assay, the spores were mixed with on-farm mash feed. Participation of the adults in the experiments was fully satisfactory. In the manure sprayed Mucor spores, the viability of eggs of roundworms and flukes reduced by 53% and 74%, respectively. Significant reductions of viability of eggs of Ascaris (60%) and Fasciola (67%) in the faeces of piglets and calves given mash feed-added Mucor spores were achieved, which demonstrates their ability to survive in the digestive tract of the animals. It is concluded that biological control of parasites could be helpful to decrease the risk of infection in animals reared by intellectually disabled adults in a care farm, and it could motivate them to accomplish new tasks.
Design of interactive multimedia courseware for data structure and algorithms - I

Field: Computer Science (Physical Sciences)

With the advancement of technology, Internet is now readily available island wide. Using this advantage, education can now take a higher step in teaching students with e-learning. Now students will be able to access teaching materials on the Internet and study at home. In order to have an efficient e-learning experience, the website needs to be interactive and simplified so that the student will be engaged with activities and let them understand the topic easier.
on Simultaneous Observations of Other Species

Field: Earth and Planetary Sciences (Physical Sciences)

The LIMS HNO 3 values are inconsistent with other LIMS measurements above about 5 mbar. During the four time periods analyzed, the LIMS HNO 3 concentrations were much higher than the HNO 3 concentrations computed using the other LIMS measurements (03, H20, NO2, and temperature). Until this inconsistency in the LIMS data is resolved, we recommend an alternative evaluation of upper-stratospheric HNO3, consistent with all other LIMS measurements, for pressure levels less than 5 mbar. The alternate method of evaluating HNO 3 makes use of a photochemical equilibrium approxi-mation to derive OH from LIMS H20 and 03; this OH is used with LIMS NO2 to derive HNO 3 above 5 mbar.
CL XI Nozzle F2 Absorption Experiment.

Field: Engineering (Physical Sciences)

Abstract : An F2-absorption diagnostic technique was developed to determine F2 densities in the flow of a 10.2-cm-long TRW CL XI nozzle. The device was transported to the site, set up, tested, and returned to TRW in two days. Hence, the diagnostic device was demonstrated to be readily transportable and to be operable in a combustion-driven, chemical-laser field environment. Cold- and hot-flow measurements up to 970 K plenum temperature, i.e., no F2 dissociation, were in agreement; therefore, this measurement appears to be reliable.
Navigating Cultures: Immigrant Mothers’ Parenting Beliefs

Field: Social Sciences (Social Sciences)

Parenting beliefs of immigrant mothers typically emerge from their culture of origin; \neach woman negotiates the new challenges that are presented in parenting their \n“American” children through her own cultural lens (Bornstein & Cote, 2004). A mixed-methods study of nine immigrant women living in New York State was conducted. The \npresent research examined the parenting beliefs of immigrant mothers who arrived in the United States after the Immigration and Nationality Act of 1965. The “developmental \nniche” model (Super & Harkness, 1996) and Bronfenbrenner’s (1986) “ecological” \nmodel provided the theoretical basis for this study. Qualitative themes that emerged \nincluded the importance of social support, the formative experience of immigration, and \nhybridized discipline styles. Findings suggest that immigrant mothers do hold unique \nparenting beliefs as a marginalized group.