Does repetition suppression in the macaque superior temporal sulcus depend on adapter stimulus duration?

Field: Neuroscience (Life Sciences)

Event Abstract Back to Event Does repetition suppression in the macaque superior temporal sulcus depend on adapter stimulus duration? Pradeep Kuravi1* and Rufin Vogels1 1 K U Leuven, Department of Neurosciences, Belgium Repetition suppression, the attenuation of neural activity for repeated stimuli, is a well-known neural phenomenon in the macaque inferior temporal (IT) cortex and is also present in homologue occipito-temporal areas of the human brain. A previous adaptation study of primary visual cortex suggests that prolonged exposure to the adapter stimuli strengthens the adaptation effect in comparison to brief exposure of the same stimuli. Here we investigate whether this property of V1 neurons prevails in IT, an area hierarchically at a higher stage. To determine this we presented the adapter stimulus for 3 durations of 300, 1500 and 3000ms and the test stimulus for 300ms. The test stimuli followed the adapter stimulus with an interstimulus interval of 300ms. Single cell recordings were performed in the macaque lower bank of the superior temporal sulcus. Two stimuli (A, B) were selected from a set of 52 complex images of various object categories, based on their response strength. These stimuli were either presented in repetition trials, i.e. repetition of the same stimulus (AA, BB), or as in alternation trials, i.e. alternation of the stimuli (AB, BA). These trials were presented in a pseudorandom order. Our data show repetition suppression for both the short duration, 300ms, adapter (p < 0.0001, 65 neurons) and the long duration, 3000ms, adapter (p< 0.0001, 65 neurons). However, in contrast to primary visual cortical neurons, the degree of repetition suppression did not differ significantly on adapter duration (300 and 3000ms). This surprising data question simple activity-dependent fatigue models of repetition suppression. Acknowledgements This work was supported by Fonds voor Wetenschappelijk Onderzoek Vlaanderen (G.0582.12N), Interuniversitaire Attractiepool, Programma Financiering (PF 10/008) and the European Community’s Seventh Framework Programme FP7/2007-2013 under grant agreement number PITN-GA-2008-290011. Keywords: adaptation, single unit activity, inferior temporal sulcus, Long adapter, repetition suppression Conference: 11th National Congress of the Belgian Society for Neuroscience, Mons, Belgium, 22 May - 22 May, 2015. Presentation Type: Poster presentation Topic: Neuroscience Citation: Kuravi P and Vogels R (2015). Does repetition suppression in the macaque superior temporal sulcus depend on adapter stimulus duration?. Front. Neurosci. Conference Abstract: 11th National Congress of the Belgian Society for Neuroscience. doi: 10.3389/conf.fnins.2015.89.00036 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 29 Apr 2015; Published Online: 05 May 2015. * Correspondence: Mr. Pradeep Kuravi, K U Leuven, Department of Neurosciences, Leuven, Belgium, pradeep.kuravi@med.kuleuven.be Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Pradeep Kuravi Rufin Vogels Google Pradeep Kuravi Rufin Vogels Google Scholar Pradeep Kuravi Rufin Vogels PubMed Pradeep Kuravi Rufin Vogels Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.