jimnoneill/paper-to-field-training huggingface dataset:
Serum Levels of Luteinizing Hormone, Follicle-Stimulating Hormone and Progesterone Throughout the Menstrual Cycle of Rhesus Monkeys12

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Serum levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), and progesterone were determined in serum samples obtained throughout the menstrual cycle of rhesus females by radioimmunoassay. During the follicular phase of the cycle, LH levels averaged 300 ng/ml, increased to peak levels of 1400 ng/ml at midcycle, reached a nadir at 200 ng/ml during the mid-luteal phase, then rose to follicular phase levels with the onset of menstruation. FSH levels were 350 ng/ml during the early follicular phase of the cycle, fell somewhat to 200 ng/ml just before the midcycle preovulatory surge, then rose to peak levels of 1500 ng/ml to coincide with the rise in LH. FSH levels also reached their nadir of 150 ng/ml during the midluteal phase of the cycle and then rose with the onset of menstruation. Progesterone levels were low during the follicular phase of the cycle and increased to peak levels of 6 ng/ml during the luteal phase of the cycle.
EDUCATIONAL QUALITY MANAGEMENT IN INTEGRATED ISLAMIC SCHOOLS (The Role of Stakeholders in Improving the Quality of Edu)

Field: Social Sciences (Social Sciences)

Education is a shared responsibility. Stakeholder involvement is very important in improving the quality of education. Stakeholders have different roles and responsibilities in realizing educational goals. Building effective partnerships and collaboration between stakeholders is the key to improving the quality of education. This article discusses the role of stakeholders in improving the quality of education based on analysis of data and facts, as well as quotes from experts' opinions. Several suggestions are also presented for increasing the role of stakeholders in education. In conclusion, by understanding the role of stakeholders and implementing appropriate strategies, schools can utilize existing potential and resources to improve the quality of education in a sustainable manner.
SH533324.07FU

Field: Agricultural and Biological Sciences (Life Sciences)

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
Effects of 2,3-butanedione monoxime on sarcoplasmic reticulum of saponin-treated rat cardiac muscle

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

We have studied the effects of 2,3-butanedione monoxime (BDM) on the sarcoplasmic reticulum (SR) of saponin-treated rat cardiac trabeculae. Rapid application of 20 mM caffeine released Ca2+ from the SR, which was detected using the fluorescent Ca2+ indicator indo 1. The amplitude of the caffeine-induced Ca2+ transient was used as an index of the Ca2+ content of the SR before, during, and after exposure to various concentrations of BDM. BDM (1-5 mM) had little effect on caffeine-induced Ca2+ release. At these levels of BDM, force was inhibited predominantly by a direct action of BDM on the myofilaments. However, with higher concentrations (5-30 mM), BDM caused a concentration-dependent decrease in the amount of Ca2+ released from the SR in response to caffeine. This action of BDM may contribute to the negative inotropic effect of the drug in intact cardiac preparations by reducing the amount of Ca2+ available for release during systole. Rapid application of BDM induced a net release of Ca2+ from the SR. Both BDM and caffeine-induced Ca2+ releases were abolished following treatment of the muscle with 10 microM ryanodine. BDM failed to release Ca2+ in the absence of ATP or after substitution of ATP with nonhydrolyzable adenine nucleotides. In contrast, caffeine released Ca2+ in the absence of ATP. The possible involvement of the Ca(2+)-uptake pump in the action of BDM on the SR is discussed.
B‐RAF V600E mutational analysis of fine needle aspirates correlates with diagnosis of thyroid nodules

Field: Medicine (Health Sciences)

Objective A mutation of B‐type RAF kinase (B‐RAF) represents the most common genetic alteration in papillary thyroid cancer (PTC), possibly signifying a more aggressive biology. Fine needle aspiration (FNA) represents the most useful initial diagnostic tool of thyroid nodules. Molecular analysis of the mutation status of B‐RAF in thyroid nodule FNAs may provide guidance for treatment planning. Study Design Cross‐sectional study. Subjects and Methods A retrospective chart review was undertaken for clinically relevant data of papillary thyroid cancer (PTC), follicular variant of PTC (FV‐PTC), and nonmalignant goiters. After blinded pathologic review, histologic and cytologic samples were analyzed by LightCycler PCR (LCPCR) with allele‐specific fluorescent probe melting curve analysis (FMCA) for the V600E mutation of B‐RAF. Results Of the 45 patient samples analyzed, B‐RAF mutation was found to be significantly higher in papillary carcinomas when compared to follicular variant of papillary thyroid carcinomas (55.6% vs 14.3%, P = 0.05). Pathologic B‐RAF mutational status significantly correlated with cytologic B‐RAF mutational status ( P < 0.0001), cytologic interpretation ( P = 0.012), and histologic diagnosis ( P = 0.011). Conclusions Determination of B‐RAF V600E mutation of thyroid nodule FNAs by LCPCR may be a useful tool to guide treatment planning. These data support investigating the utility of this molecular marker in a prospective manner.
HOW LIGHTING DYNAMICS CREATE SOCIAL INTERACTIVE GAME

Field: Social Sciences (Social Sciences)

By entering preschool age, children’s understanding of the world increase significantly and their interactive worlds extend excessively. This will impact not only their social connections but also their connections to the natural world. Preschool age is suitable for teaching concepts such as nurturing plants. By employing interactive game design, children can learn what are needed for a plant to grow properly. Pre-schoolers are attracted to gamified activities. Preschool is a proper environment to deploy interactive game design because it leads to formation of interactive relationships between children, teachers and the environment. In addition to forming social relationships, this design forms a learning environment in which knowledge exchange happens. A preschool located in Tehran city was chosen as a case study. Observation based method was used for collecting practical data in order to suggest an interactively gamified solutions and 56 students were observed in this environment. The collected data was used in designing a gamified concept. As the focus was on enhancing the learning process through the social gaming, the correlation between three theories, MDA framework, key characteristics of a learning game and social characteristics of player experience, was studied and a concept was suggested. The concept uses lighting dynamics to form a socially educational game. Lighting dynamics invite children to participate in the game. A paper prototype got tested with 39 preschoolers and its affordance was successful in attracting children to the learning concept.
Modelling and Simulation of Big Data Networks

Field: Computer Science (Physical Sciences)

Modelling and simulation of Big data (BD) networks used to be technical problem before years, but now is opportunity. BD processioning and analytics are developing every day, useful teletraffic models describe and suggest decisions in such networks. Some of the untapped data are coming from sensors, devices, third parties, Web applications, and social media. Some BD sources feed data unceasingly in real time. Combining this, BD is not just about giant data volumes, it is also about an extraordinary diversity of data types, delivered at various speeds and frequencies. In this paper we analyzed the teletraffic models, modelling and analytical solutions for BD networks and are simulated heavy traffic models.
Motivation and specialty preferences among final year medical students in east of Democratic Republic of Congo: Cross sectional study at Catholic University of Graben

Field: Health Professions (Health Sciences)

Objective. In the Democratic Republic of Congo, medicine is practiced in conditions of shortage of human and material resources for certain specialties, as in other countries in sub-Saharan Africa. This study aimed to determine the preferred specialties and motivations of choice for final medical students at the Catholic University of Graben. Methods. This was a prospective, cross-sectional series of 94 finalist medical students from the Catholic University of Graben, academic year 2021 2022. We used a semi-structured questionnaire which was administered online (Kobocollect-Enketo) between January and February 2024. Results. Among the 104 finalist students, 94 agreed to participate. Of these 94 participants, 49 (52.13%) were male. The average age was 28.40 ± 2.62 years. Everyone wanted to specialize. The most preferred specialties were: general surgery (30.85%), public health (25.53%), internal medicine (24.47%), pediatrics (21.28%), anesthesia & intensive care (19.15%) and obstetrics gynecology (13.83%). The most frequent motivations were: specialty theme passion (48.94%), social reasons (31.91%) and the vocation aroused by the supervisors (30.85%). Conclusion. The finalist medical students all intend to specialize in the different specialties of medicine. Their choice is more motivated by specialty theme passion. Incentive and guidance policies are necessary to facilitate access to specialization with a view to filling the shortage in certain areas.
III.1.2 HLA matching and mismatching

Field: Medicine (Health Sciences)

SECTION III: The transplant recipient from initial transplant hospitalization to 1 year post-transplant 54 different blood group A antigens.Transplantation 1990; 49: kidney donor trigger the recipient's immune response [954][955][956][957][958][959][960] and lead to acute rejection.Immunosuppressive drugs 30
Assessing post-socialist urban change with Landsat data; Case study Berlin, Germany

Field: Earth and Planetary Sciences (Physical Sciences)

Germany's capital Berlin has undergone tremendous urban structural changes in the past decades since the German re-unification. In addition to processes of urban growth and densification, processes of urban shrinkage occur in Berlin. As these processes have great impact on urban ecosystems and therefore on human well-being, monitoring of respective changes is required to support sustainable urban development. This study therefore aims to detect and quantify the urban structural changes in Berlin and its outskirts since the re-unification in 1989. Hence, two Landsat TM5 data sets covering the city of Berlin and adjacent rural areas were obtained, geometrically corrected and layer stacked. Subsequently, the layer stack was subject to a multi-temporal principal component analysis. Thereafter, an unsupervised classification of selected principal components (PC3, PC4, and PC6) was carried out. The change detection was conducted based on the classification results and yielded reliable results of approximately 90% accuracy. The change analysis showed that besides alternations in agricultural crops major changes occurred on the outskirts of Berlin, mostly in terms of large-area construction activity in the former eastern part. Furthermore, contrary processes could be identified in the former border region of the divided city. Whilst there was building activity in the more central parts, succession and renaturation were detected in most other parts of the Berlin Wall. The study showed that remote sensing has proven to be an appropriate tool to assess contrary post-socialist urban structural changes of Berlin, Germany.
Differential effects of chromatin regulators and transcription factors on gene regulation: a nucleosomal perspective

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Motivation: Chromatin regulators (CR) and transcription factors (TF) are important trans-acting factors regulating transcription process, and many efforts have been devoted to understand their underlying mechanisms in gene regulation. However, the influences of CR and TF regulation effects on nucleosomes during transcription are still minimally understood, and it remains to be determined the extent to which CR and TF regulatory effect shape the organization of nucleosomes in the genome. In this article we attempted to address this problem and examine the patterns of CR and TF regulation effects from the nucleosome perspective. Results: Our results show that the CR and TF regulatory effects exhibit different paradigms of transcriptional control in Saccharomyces cerevisiae. We grouped yeast genes into two categories, ‘CR-sensitive’ genes and ‘TF-sensitive’ genes, based on how their expression profiles change upon deletion of CRs or TFs. We found that genes in these two groups have very different patterns of nucleosome organization. The promoters of CR-sensitive genes tend to have higher nucleosome occupancy, whereas the promoters of TF-sensitive genes are depleted of nucleosomes. Furthermore, the nucleosome profiles of CR-sensitive genes tend to show more dynamic characteristics than TF-sensitive genes. These results reveal that the nucleosome organizations of yeast genes have a strong impact on their mode of regulation, and there are differential regulation effects on nucleosomes between CRs and TFs. Availability: http://www.utoronto.ca/zhanglab/papers/bioinfo_2010/ Contact: zhaolei.zhang@utoronto.ca Supplementary information: Supplementary data are available at Bioinformatics online.
Developing Green Feed Toward Environment Sustainability in Freshwater Aquaculture in Indonesia

Field: Environmental Science (Physical Sciences)

Environment performance is critical in freshwater aquaculture subject to fish diet formulation due to its negative impacts such as waters eutrophication and water quality. Problem on the water quality is not only impact on the fish growth itself but also will impact on the aquaculture business sustainability. Sustainability of fresh water aquaculture mainly relates to its environment performance subject to various resource management. Freshwater aquaculturist face a challenge to manage such resources to achieve their competitive advantage. The Resource-Based View (RBV) theory highlight on the firm ability to achieve their competitive advantage which dynamic capability is one of the main concern. The intensive freshwater aquaculture relied on feed as the primary factor to increase fish growth and production mainly. The feed might contribute 20 -30% waste in environment. The objective of this study is to identify in what extend green feed technology can support the environment sustainability. This study use combination of field data experimental result and semi structure interview to the fish farmers and fish agents. Developing green feed is one of the solution to gain environment sustainability. Various commercial diets have been fed on freshwater cultured fishes using both cages and ponds. As the results, low digestible diet and wasted diet has increased N and P in water, which will decline water quality at certain level. It is recommended to formulate green feed using low P and high digestible ingredients as well as any supplement material, which could increase diet digestibility. Minimize waste possible done through increasing feeding efficiency and use multiple cages, polyculture, aquaponics system in ponds, and alternative fish by-product in the diet. Technology to support the environment sustainability can be implemented by arranging the C-N ratio of the water, which will raise production of both bioflocs and bio-films. Stocking multi species different food web is recommended.
Stock Identification of Fraser River Sockeye Salmon Using Microsatellites and Major Histocompatibility Complex Variation

Field: Agricultural and Biological Sciences (Life Sciences)

The utility of DNA-based variation for stock identification was evaluated for Fraser River sockeye salmon Oncorhynchus nerka. For this evaluation, the variation at 14 microsatellite loci and one major histocompatibility complex (MHC) locus was determined from approximately 13,000 fish from 47 populations in the drainage. Genetic differentiation among the populations was observed, the overall FST value for the 14 microsatellite loci surveyed being 0.054 and that for the MHC locus being 0.215. The variation among regions and populations within regions was approximately 20 times as great as that of the annual variation within populations for the microsatellite loci and 28 times as great for the MHC locus. The power of a microsatellite locus for population-specific identification in simulated mixture samples was positively correlated with the number of observed alleles at the locus. Analysis of simulated mixtures indicated that the mean percentage error of estimated stock compositions was less than 1% per population, with a standard deviation of approximately 3% for a mixture sample size of 150 fish. Estimated stock compositions of a known sample of radio-tagged sockeye salmon indicated that the mean percentage error was 1% per population and 1% per run-time group. The use of DNA variation to estimate stock compositions in the management of the 2002 Fraser River sockeye salmon fisheries indicated the early arrival of the late run in the Fraser River. Stock identification based on DNA-level variation will probably become the preferred method in Pacific salmon applications in the near future.
Supplementary Foreign Language Education

Field: Arts and Humanities (Social Sciences)

As a structural subdivision of the Kutafin Moscow State Law University (MSAL), the Department of Legal Translation implements a number of unique language education programs, providing its graduates with the opportunity to become a part of the elite international community of lawyers. Language education is based on the individual needs of potential students and allows you to choose the most comfortable language program in legal English, French, German, Spanish and Chinese.Maintaining the quality and timely updating of programs to meet the growing needs of modern society are among the priority tasks of the Institute, as a subdivision of the country’s leading law university. The introduction of new educational technologies and teaching models, diversification and reorientation of programs towards practical application and communication meets modern trends in the development of education. The training of highly qualified specialists in the field of a professional foreign language of jurisprudence increases the competitiveness and demand for graduates both in their professional environment — lawyers, and in related professions — such as a translator or teacher
RESULTADOS DE LA DICTAMINACIÓN DE 213 PROYECTOS CREDITICIOS DE GANADERÍA DE CARNE

Field: Business, Management and Accounting (Social Sciences)

Credit is a fundamental input for production. One of its major limitations is default payments. Quality of credit portfolios is directly linked to the quality of the projects that are used to generate them. This study assesses the quality of a non probabilistic sample of 213 livestock projects to which credit was granted by a financial institution in 3 consecutive years. Between 15-20 projects where obtained in each of the 12 regional branches covering the national territory. Fifteen different types of deficiencies where found. The most frequent deficiencies found were: the use of nominal interest rates, (100%), omission to include production costs (44%) including incomes from other activities (43%), and high calving rates (25%). The number of deficiencies per type of project was of 5.5 in the case of enterprises dealing with double purpose production (beef-milk); 6.3 for cow-calf production, and 6.5 for pasture fattening. Results were highly significant for the deficiencies by branches and significant for type of project. No statistical differences were found in relation to the year of preparation. There are statistical differences (P< 0.05) in deficiencies found between double purpose and cow-calf projects as well as between double purpose and pasture fattening. The exaggerated frequency of deficiencies, together with the fact that they were not detected by regular institutional supervision mechanisms, shows an obvious failure of these mechanisms but more over, it shows the possibility that these deficiencies are considered by the institution as “accepted problems” or “understood values”, since there are other priorities regarding credit policies such as use of nominal interests rates, short amortization periods, etc.
Relationship of Histology to Prognosis in Thyroid Carcinoma

Field: Medicine (Health Sciences)

Prognosis in carcinoma of the thyroid varies more widely and consistently with the histologic pattern than perhaps any other neoplasm. This fact has been observed particularly in relation to the papillary forms, which have a good although not necessarily an excellent prognosis. The follicular form is associated with only a fair prognosis, and the anaplastic forms are invariably rapidly fatal. A major proportion of the differentiated carcinomas of the thyroid exhibit a mixed pattern of both papillary and follicular elements. The clinical implications of the respective roles of these two components in the mixed forms have not been emphasized by most studies of thyroid cancer. The usual classifications do not recognize the mixed forms as such, assigning given tumors to either papillary or follicular categories according to predominant cell type. In an effort to evaluate the clinical significance of predominance of either the papillary or follicular elements in the mixed
Detection and Identification by PCR of a Highly Virulent Phylogenetic Subgroup among Extraintestinal Pathogenic Escherichia coli B2 Strains

Field: Immunology and Microbiology (Life Sciences)

ABSTRACT Closely related Escherichia coli B2 strains O1:K1, O2:K1, O18:K1, and O45:K1 constitute a major subgroup causing extraintestinal infections. A DNA pathoarray analysis was used to develop a PCR specific for this subgroup that was included in the multiplex phylogenetic-grouping PCR method. Our PCR may serve to identify this virulent subgroup among different ecological niches.