jimnoneill/paper-to-field-training huggingface dataset:
Syntheses of Molybdenum Oxo Benzylidene Complexes

Field: Chemistry (Physical Sciences)

The reaction between Mo(O)(CHAro)(ORF6)2(PMe3) (Aro = ortho-methoxyphenyl, ORF6 = OCMe(CF3)2) and 2 equiv of LiOHMT (OHMT = O-2,6-(2,4,6-Me3C6H2)2C6H3) leads to Mo(O)(CHAro)(OHMT)2, an X-ray structure of which shows it to be a trigonal bipyramidal anti benzylidene complex in which the o-methoxy oxygen is coordinated to the metal trans to the apical oxo ligand. Addition of 1 equiv of water (in THF) to the benzylidyne complex, Mo(CArp)(OR)3(THF)2 (Arp = para-methoxyphenyl, OR = ORF6 or OC(CF3)3 (ORF9)) leads to formation of {Mo(CArp)(OR)2(μ-OH)(THF)}2(μ-THF) complexes. Addition of 1 equiv of a phosphine (L) to Mo(CArp)(ORF9)3(THF)2 in THF, followed by addition of 1 equiv of water, all at room temperature, yields Mo(O)(CHArp)(ORF9)2(L) complexes in good yields for several phosphines (e.g., PMe2Ph (69% by NMR), PMePh2 (59%), PEt3 (69%), or P( i-Pr)3 (65%)). The reaction between Mo(O)(CHArp)(ORF9)2(PEt3) and 2 equiv of LiOHMT proceeds smoothly at 90 °C in toluene to give Mo(O)(CHArp)(OHMT)2, a four-coordinate syn alkylidene complex. Mo(O)(CHArp)(OHMT)2 reacts with ethylene (1 atm in C6D6) to give (in solution) a mixture of Mo(O)(CHArp)(OHMT)2, Mo(O)(CH2)(OHMT)2, and an unsubstituted square pyramidal metallacyclobutane complex, Mo(O)(CH2CH2CH2)(OHMT)2, along with ethylene and ArpCH═CH2. Mo(O)(CHArp)(OHMT)2 also reacts with 2,3-dicarbomethoxynorbornadiene to yield syn and anti isomers of the "first-insertion" products that contain a cis C═C bond.
Is a Critical Interval of the Circadian Pacemaker at Dusk Responsive to Light and Melatonin Responsible for the Timing of Estrus in the Romney Marsh Ewe?

Field: Neuroscience (Life Sciences)

Two experiments, using Romney Marsh ewes, tested for the existence and role of a critical interval of the circadian pacemaker located near dusk that may be integrally involved in the precise timing of the breeding season. Groups of Romney Marsh ewes ( n = 6) were provided with exogenous melatonin by injection at dusk (Experiment 1) or by infusion at dawn or subjected to extended darkness at dawn (Experiment 2) from the winter to the summer solstice before being exposed to natural photoperiod at latitude 35° S. Other than the experi mental protocols, all animals were held in natural photoperiod. The onset of the breeding season (defined as cyclic ovarian activity as indicated by plasma progesterone monitoring) was normal in those animals treated with morning melatonin but was delayed in those animals treated with melatonin at dusk or extended darkness at dawn compared to controls in natural photoperiod (p < .01). Exogenous melatonin at dusk was associated with a phase advance of the onset of the circadian pacemaker (as measured by endogenous melatonin in acutely extended darkness); additional darkness at dawn was associated with a phase delay of both the onset and the offset of the circadian pacemaker. Exoge nous morning melatonin did not change the phase of the circadian pacemaker relative to the controls. The results are consistent with an external coincidence model of seasonal breeding in which a critical interval of the circadian pacemaker requires exposure to light during spring/summer to time estrus correctly. The proposed critical interval appears to be located near dusk in this model and is phase locked to the circadian pacemaker. The effect of the exogenous melatonin on the timing of the breeding season is similar to darkness when administered at dusk but is not equivalent to darkness at dawn. The timing of anestrus was not affected by any of the experimental treatments and may reflect a common response to an environmental influence.
Peran Festival Budaya Dalam Pengembangan Nilai Religius Dan Nilai Sosial Di Desa Gosari Kecamatan Ujungpangkah Kabupaten Gresik

Field: Social Sciences (Social Sciences)

Cultural festivals are a series of positive activity processes conducted in certain areas to maintain and preserve local and national culture. They are held to include the participation of the community, related parties, and the government together. This research was a type of qualitative research conducted in Gosari Village, Ujungpangkah District, Gresik Regency. Data sources were obtained from the Village Head, Chief Executive, Head of WAGOS Board (Gosari Natural Tourism), religious, and community leaders, and supported by documents and archives. Data collection was conducted through interviews, observation, and documentation techniques. The research findings showed that the Gosari cultural festival is held once a year with a series of activities which include: Resik Sendang Icleaning the bathing place), Kirab Warga (mutually cleaning the environment), Ngadusi Rojo Koyo (bathing the cows), Traditional Snacks Market, review of the book: “History and Mythology of Gosari”, Performance of Traditional Dance and Ludruk Art. The values developed in the implementation process are social, religious, and traditional values. Cultural festivals play a role in developing religious and social values, namely through the optimization in the field of education which is collaborative with nature, and the habituation of community traditions which are held regularly and continuously.
Modification of Phospholipids with Lipases and Phospholipases

Field: Chemistry (Physical Sciences)

Different commercial lipases and phosphoiipases were studied in the hydrolysis and transesterification of synthetic phosphatidylcholine and soybean lecithin. Wide variations in the lipase and phospholipase activities and in the protein contents of the preparations were observed. The substrate specificity varied between different enzymes. A high degree of hydrolysis of synthetic and soybean phospholipids was achieved with both types of enzymes.Enzymes immobilized on Celite were used in the transesterification of dimyristoyl phosphatidylcholine and oleic acid. The conversions were carried out both without solvent and in the presence of toluene. The amount of modified phosphatidylcholine was measured using HPLC. The highest amount of modified phosphatidylcholine was obtained in solvent-free transesterification. The best results were obtained with Aspergillus niyer lipase.
Effect of interferon therapy on indomethacin-sensitive immunoregulation in the peripheral blood mononuclear cells of renal cell carcinoma patients.

Field: Medicine (Health Sciences)

The effect of interferon (IFN) therapy on prostaglandin (PGE)-synthesizing immunoregulatory cell function was assessed in the peripheral blood mononuclear cells of renal cell carcinoma patients. Ten patients were treated daily for 28 days with either 1 X 10(6) IU (five patients) or 10 X 10(6) IU (five patients) of leukocyte IFN. Patient cells were assessed for phytohemagglutinin (PHA) responsiveness in the presence and absence of the PGE synthetase inhibitor indomethacin. Progressive impairment in PHA responsiveness was found in all patients by the end of 28 days of therapy. It was associated with increased levels of indomethacin-sensitive suppressor function. Change in any of the patients studied was not correlated with IFN dose level. There was no correlation between clinical response to IFN and alterations in these parameters of immune function. In co-culture experiments, preincubation of glass-adherent cells with IFN led to increased indomethacin-sensitive regulatory function. These results suggest that IFN can produce progressive impairment of PHA-induced lymphoproliferation by increasing PGE-synthesizing immunoregulatory cell activity.
ChemInform Abstract: Lithium Aluminum Hydride Reduction of N‐Aziridinylimines to Hydrocarbons.

Field: Chemistry (Physical Sciences)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Vegetable Waste Compost as Substrate for Melon

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract The suitability of compost from horticultural residues as a growing medium in vegetable crop production was compared with the popular rock wool and coconut coir waste substrate. Physical and physio-chemical properties were initially characterized to adjust the management of this substrate for horticultural purposes. Leaching experiments were carried out with acid solution and standard nutrient solution. Two experiments were conducted to compare this compost with rock wool and coconut coir waste in terms of yield and fruit quality of a melon crop. The compost was found to initially have high salt content and a high pH. The results suggested that compost seems to be an acceptable growing medium for soilless vegetable production, provided that it is leached prior to use. Once it is leached, the compost is an acceptable substitute for rock wool and coconut coir waste.
FE Switching in SrRuO3/NiFe<inf>2</inf>O<inf>4</inf>/BaTiO3/LSMO Heterostructures on SrTiO<inf>3</inf>Substrates

Field: Materials Science (Physical Sciences)

This work reports the successful fabrication of an all-oxide heteroepitaxial structure with a bilayer tunnel junction consisting of ferroelectric and ferrimagnetic layers. Each layer of the structure exhibits high crystallinity and well-defined interfaces. The transport properties of the junction are found to be well described by the characteristics of an asymmetric ferroelectric tunnel junction.
Thyrotropin releasing hormone (TRH) in the hippocampus of Alzheimer patients

Field: Neuroscience (Life Sciences)

Thyrotropin-releasing hormone (TRH) is best known for its hypothalamic neuroendocrine role in regulating thyroid function. In extra-hypothalamic regions in vitro, we have shown TRH to have a protective effect against synaptic loss and neuronal apoptosis. A role for TRH in Alzheimer's disease (AD) has not been established previously. In this study, we examined the content of the TRH peptide in the hippocampus of elderly controls (n=5) and AD patients (n=7) by radioimmunoassay (RIA). The TRH concentration was decreased in the AD hippocampus compared to normal elderly controls (p > 0.01). In a separate series of experiments utilizing primary cell cultures made from rat hippocampus, TRH peptide concentration was depleted by the addition of TRH antiserum. TRH withdrawal was found to enhance the activity of glycogen synthetase kinase-3 (GSK-3β), a critical enzyme necessary for the phosphorylation of tau, as well as the phosphorylation of the tau protein itself. This TRH depletion induced upregulation in phosphorylation that was observed to initiate axonal retraction in cultured neurons. These data suggest that TRH within the hippocampus can regulate the activity of various proteins by phosphorylation/dephosphorylation that may be involved in the pathogenesis of AD.
Alternate Pathways of Certification as Ideological State Apparatuses: A Critical Race Theory Methodology of Alternate Pathways of Certification in Arizona

Field: Social Sciences (Social Sciences)

A review of the literature on alternate pathways of certification and anti-racist curriculum revealed that the alternate pathways of certification requirements vary from the traditional pathways of certification that often require a course on multicultural education or diversity. In Arizona, there are 15 main alternate teacher preparation programs. Due to the federal policy of No Child Policy and teacher shortages (primarily in Arizona), there has been an increase in the number of teachers certified through an alternative method (Boe, Cook, & Suderland, 2008; McLeskey & Billingsly, 2008). The advantage for the school districts and the preservice teachers is that alternate pathways is a cheap and quick way into the classroom. But for students, especially Black students, these preservice teachers are not introduced to anti-racist curriculum and pedagogies that help address racism and combat anti-Blackness. These alternate pathways reflect neoliberal approaches to solving public problems by sidestepping racism and adopting market driven approaches to a solution. This study examines what 15 institutions of alternate pathways of certification are embedding in their programs. I examine the programs webpages and perform an autopsy on the courses they require their pre-service teachers take and critique their syllabi to determine what readings, topics, and other material they are being exposed to help offset racism in the classroom. The overall findings confirmed that 14 of the 15 institutions, selected by the Arizona Department of Education to be alternate pathways of certification, did not offer anti-racist curriculum nor even addressed the student population that were non-white. The findings support the existing alternate certification literature that most teachers have not been properly trained to teach students (Banks, 2001; Darling-Hammond, 2010; Quigney, 2010; Rosenberg & Sindelar, 2005) and that policymakers, like the Arizona Department of Education, are mostly apprehensive about the efficiency of teacher preparation programs (Boyd, Grossman, Lankford, Loeb, & Wyckoff, 2008) and not about Black students in the classroom.
Preparing for the workplace: fostering generic attributes in allied health education programs.

Field: Health Professions (Health Sciences)

Allied health curricula need to extend beyond the learning of discipline-specific skills to encompass broader learning goals. In particular, the acquisition of generic skills is necessary to enable graduates to function more competently and confidently within their rapidly changing work, professional, and societal environments. In health sciences education particularly, the rate of change in practice and education is rapid and unprecedented. If educators focus on components of the curriculum rather than the entire learning experience, they are likely to significantly limit the students' acquisition of such generic skills. To achieve the desired generic skills outcomes, an overarching, integrated, and consistently applied curriculum strategy is advocated. This article considers a number of such strategies relevant to allied health education.
Immunologic Unresponsiveness to Allergic Thyroiditis in Guinea Pigs

Field: Immunology and Microbiology (Life Sciences)

Summary Immunologic unresponsiveness to autoimmune thyroiditis was induced in guinea pigs. A single injection of homologous thyroglobulin accompanied by eight daily injections of cyclophosphamide prevented the onset of thyroiditis after a disease-inducing challenge of guinea pig thyroglobulin. An injection of guinea pig thyroglobulin or cyclophosphamide alone did not produce specific immunity or unresponsiveness to a subsequent challenge with thyroglobulin. Picrylated guinea pig thyroglobulin or bovine thyroglobulin, in conjunction with cyclophosphamide, did not induce immunologic unresponsiveness to guinea pig thyroglobulin.
Power-constrained CMOS scaling limits

Field: Engineering (Physical Sciences)

The scaling of CMOS technology has progressed rapidly for three decades, but may soon come to an end because of power-dissipation constraints. The primary problem is static power dissipation, which is caused by leakage currents arising from quantum tunneling and thermal excitations. The details of these effects, along with other scaling issues, are discussed in the context of their dependence on application. On the basis of these considerations, the limits of CMOS scaling are estimated for various application scenarios.
Contact Problems for Two Anisotropic Half-Planes with Slits

Field: Mathematics (Physical Sciences)

Abstract The problem of a stressed state in a nonhomogeneous infinite plane consisting of two different anisotropic half-planes and having slits of the finite number on the interface line is investigated. It is assumed that a difference between the displacement and stress vector values is given on interface line segments; on the edges of slits we have the following data: boundary values of the stress vector (problem of stress) or displacement vector values on the one side of slits, and stress vector values on the other side (mixed problem). Solutions are constructed in quadratures.
Diagnosis of Toxoplasma parasitemia in patients with AIDS by gene detection after amplification with polymerase chain reaction

Field: Medicine (Health Sciences)

We sought evidence of toxoplasma parasitemia among 37 people with active or dormant Toxoplasma gondii infection or no evidence of infection. DNA was extracted from erythrocyte-free portions of blood samples, and the T. gondii B1 gene was amplified by the polymerase chain reaction. Evidence of T. gondii parasitemia was found in six patients with severe immunosuppression from AIDS and clinical evidence suggestive of or compatible with toxoplasmosis. Results were negative for patients unlikely to have active toxoplasmosis. Gene detection after amplification with the polymerase chain reaction is a promising test for detection of parasitemia, and parasitemia should be tested for in patients with AIDS and unexplained fever or central nervous system abnormalities.
Potent Oxidation of DNA by Haloquinoid Disinfection Byproducts to the More Mutagenic Imidazolone dIz via an Unprecedented Haloquinone-Enoxy Radical-Mediated Mechanism

Field: Chemistry (Physical Sciences)

Halogenated quinones are a class of carcinogenic intermediates and newly identified chlorination disinfection byproducts in drinking water. We found recently that halogenated quinones could enhance the decomposition of hydroperoxides independent of transition-metal ions and formation of the novel quinone enoxy/ketoxy radicals. Here, we show that the major oxidation product was 2-amino-5-[(2-deoxy-β-d-erythro-pentofuranosyl)amino]-4H-imidazol-4-one (dIz) when the nucleoside 2'-deoxyguanosine (dG) was treated with tetrachloro-1,4-benzoquinone (TCBQ) and t-butyl hydroperoxide (t-BuOOH). The formation of dIz was markedly inhibited by typical radical spin-trapping agents. Interestingly and unexpectedly, we found that the generated quinone enoxy radical played a critical role in dIz formation. Using [15N5]-8-oxodG, dIz was found to be produced either directly from dG or through the transient formation of 8-oxodG. Based on these data, we proposed that the production of dIz might be through an unusual haloquinone-enoxy radical-mediated mechanism. Analogous results were observed in the oxidation of ctDNA by TCBQ/t-BuOOH and when t-BuOOH was substituted by the endogenously generated physiologically relevant hydroperoxide 13S-hydroperoxy-9Z,11E-octadecadienoic acid. This is the first report that halogenated quinoid carcinogens and hydroperoxides can induce potent oxidation of dG to the more mutagenic product dIz via an unprecedented quinone-enoxy radical-mediated mechanism, which may partly explain their potential carcinogenicity.
A Twitter Social Contagion Monitor

Field: Computer Science (Physical Sciences)

We describe and validate a system for monitoring social contagions on Twitter: social movements, rumors, and emotional outbursts that spread from person to person in a viral manner. We use Twitter streams to monitor the spread of these phenomena through human social and information networks. This system, the contagion monitor, parses Twitter posts to identify emerging phenomena, as captured in hashtags, URLs, words and phrases, or account-handles, and then determines the extent to which a particular phenomenon spreads via the social network (in contrast to its spread via news broadcasts or independent adoption) and locates the contagion within Twitter communities. The monitor approximates the adoption threshold of a social contagion by measuring the fraction of Twitter users who were "infected" by the contagion (e.g., joined a particular social movement) after more than one of their friends had done so. Finally, the monitor makes a judgment about whether the phenomenon has reached critical mass, which is defined as the point where a social contagion begins spreading rapidly and breaches the social boundaries of its early adopter group. We test our prototype monitor on two data sources - an ongoing stream of tweets grouped by user-added hashtags and a collection of posts by a monitored set of Nigerian Twitter users - before productionalizing. We use the Amazon Mechanical Turk platform to evaluate the performance on both data sources. In both cases, we find that our approach successfully distinguishes between high-threshold and low-threshold social contagions.
The case-report of successful repair of atrial septal defect in 18-monthold child with TAR syndrome

Field: Medicine (Health Sciences)

Успех хирургической коррекции врожденного порока сердца зависит от ряда факторов. Одним из таких факторов является сопутствующая патология, учет которой еще на этапе планирования операции позволяет оценить периоперационный риск и разработать меры по снижению частоты осложнений. В данной работе представлено описание успешной коррекции дефекта межпредсердной перегородки у маленького ребенка с сопутствующим синдромом TAR. Синдром TAR – крайне редкое генетическое заболевание, основными проявлениями которого являются тромбоцитопения и отсутствие лучевых костей. Тромбоцитопения при данном синдроме нередко приводит к жизнеугрожающим кровотечениям, что в большей степени актуально для детей до 2 лет жизни. В настоящем сообщении описаны этапы обследования пациента, выбор тактики хирурги- ческого лечения и ведения ребенка в раннем послеоперационном периоде.
Preparation and application of monoclonal antibody against adenovirus 3 in diagnosis of keratoconjunctivitis caused by adenovirus

Field: Medicine (Health Sciences)

目的 制备特异性抗腺病毒3型(ADV-3)的单克隆抗体(mAB),并用于腺病毒性角膜结膜炎的临床实验室诊断.方法 用密度梯度超速离心技术纯化ADV-3免疫5只BALB/c 小鼠,取脾细胞及骨髓瘤细胞按常规方法融合、筛选、克隆化及腹水注射制备mAb.采用ELISA 及免疫组织化学技术进行鉴定.结果 经3次克隆化获得了3株可分泌抗ADV-3 mAb的杂交瘤细胞株,经多次复苏传代仍能稳定分泌抗体,分别命名为E7、B9和G11.1株(E7)Ig重链为IgG2b,2株(B9、G11)为IgG1,轻链均属于κ型.ELISA效价均＞104,相对亲合力E7＞B9＞G11,相对亲合力常数分别为8.14×109±1.48、2.03×108±0.43和1.63×107±0.15.腹水中mAb滴度为1×105～1×106.用抗腺病毒ADV-3 E7检测临床诊断为病毒性角膜结膜炎患者标本30例,阳性者20例,阳性率66.7%,PCR检出阳性者21例,阳性率70%,两种检测方法的阳性检出率差异无统计学意义(P＞0.05).结论 3株杂交瘤细胞株分泌的抗体对ADV-3抗原具有高特异性和亲和力,用于腺病毒性角膜结膜炎的临床诊断具有速度快、阳性率高的优点。
Secured mobile messaging

Field: Computer Science (Physical Sciences)

SMS messages are one of the popular ways of communication. Sending an SMS is cheap, fast and simple. When confidential information is exchanged using SMS, it is very difficult to protect the information from SMS security threats like man-in-middle attack, DOS attack as well as ensure that the message is sent by authorized senders. These papers describe solution that provides SMS security that guarantees provision of confidentiality, authentication, and integrity service. These provide hybrid compression encryption technique to secure the SMS data. The proposed techniques encrypt the SMS Elliptic curve encryption techniques and compress the encrypted SMS to reduce its length this document using lossless compression techniques.