jimnoneill/paper-to-field-training huggingface dataset:
A single base insertion of the 4-alpha-galactosyltransferase gene led to the deficiency of Gb3 biosynthesis.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

cDNAs for alpha 1,4 galactosyltransferase (A4GALT) have been isolated. To explore the molecular basis of the p phenotype in Japanese donors, we analyzed the A4GALT gene sequences of normal and p phenotype samples. The coding region in the A4GALT gene for DNA sequencing was amplified by PCR amplification. A4GALT expression vectors for individual were constructed by PCR amplification of the coding region using primers and subsequent subcloning into an expression vector. The expression of Gb3/CD77 antigen on the cell surface was evaluated by flow cytometry and by immunochemical techniques. All individuals with the p phenotype were found to have a single base insertion (A4GALT/insC) at the same nucleotide position. Neither the transfectant cells with a mutant gene (A4GALT/insC) of donor origin or those with a synthesized mutant gene (A4GALT/insC-Mu) expressed Gb3 antigen indicating that the presence of A4GALT/insC diminished the A4GALT enzyme activity. In addition, an allele-specific PCR (ASP) system was developed in which of the p phenotype with A4GALT/insC can be unambiguously discriminated from normal donors. Based on the finding that a single base insertion (A4GALT/insC) diminishes A4GALT activity, an ASP assay was developed to detect individuals with this particular p phenotype.
[Evaluated Cases of Anastomotic Recurrence in Colorectal Cancer].

Field: Medicine (Health Sciences)

Anastomotic recurrence in 6 colorectal cancer cases during the postoperative surveillance between 2008 and 2015 was evaluated retrospectively. Five cases had undergone DST anastomosis for sigmoidectomy and proctectomy. They had a pathological tendency to have T3 tumor and deeper, positive lymph node metastases and positive lymphatic and vascular invasion. There were 2 cases with the anastomotic recurrence diagnosis 6 to 8 months after the primary tumor resection while 4 resected cases had recurrent tumor depth of T3, though 3 cases were diagnosed 1 year after the primary tumor resection. Anastomotic recurrence should be considered a few months after primary tumor resection.
MICRORNA-122 AS A BIOMARKER ASSOCIATED WITH OXIDATIVE STRESS IN PATIENTS SUFFERING FROM METABOLIC DISEASES

Field: Medicine (Health Sciences)

Background: Recent evidence has shown that circulating microribonucleic acid (miRNA) has been related to many diseases either as an inhibitor or a stimulant factor, among them miRNA-122 which has proven through studies its relationship with insulin resistance, an adversative lipid profile, obesity, type 2 diabetes, and metabolic syndrome in several studies; however, the mechanisms involved are unknown.This study investigates the role of miRNA-122 expression in overweight patients suffering from metabolic disorders such as diabetes and hypertension and its relationship to the development of oxidative stress in patient groups.Materials and Methods: 30 patients with type 2 diabetes mellitus (T2DM), 30 people with hypertension (HTN), 30 patients with T2DM+HTN, and 30 healthy persons who served as controls were enrolled in this study.An ARCHITECT c4000 clinical chemistry analyzer was used to assess lipid profiles.The sandwich immunodetection approach was used to assess whole blood hemoglobinA1c.By colorimetric methodology, catalase activity (CAT), superoxide dismutase activity (SOD), malondialdehyde (MDA) levels, and advanced oxidation protein products (AOPPs) levels were measured.The expression of serum miRNA-122 was determined using the quantitative polymerase chain reaction. Results:The activity of SOD and CAT in patient groups was found to be substantially lower than in the control group (p < 0.05), whereas MDA and AOPP concentrations were found to be significantly higher in patient groups compared to the control group (p < 0.05).When patient groups were compared to control groups, the miRNA-122 level was higher in the patients (p< 0.05).Conclusions: miRNA-122 expression is involved in the pathogenesis of T2DM and HTN-induced oxidative stress, there is a reciprocal relationship between the increase in gene expression of the miRNA-122 and the increase in oxidative stress accompanied by a decrease in the effectiveness of antioxidant enzymes, which leads to the development of the disease.
A review of verbal and non-verbal human–robot interactive communication

Field: Computer Science (Physical Sciences)

In this paper, an overview of human–robot interactive communication is presented, covering verbal as well as non-verbal aspects. Following a historical introduction, and motivation towards fluid human–robot communication, ten desiderata are proposed, which provide an organizational axis both of recent as well as of future research on human–robot communication. Then, the ten desiderata are examined in detail, culminating in a unifying discussion, and a forward-looking conclusion.
The Dangers Associated with Female Adolescents Consuming Nyaope Drug in Butterworth, South Africa

Field: Social Sciences (Social Sciences)

Abstract Nyaope is a potent drug that is currently challenging South Africa; its ramifications have destroyed the country’s youth. The study described in this paper sought to explore the dangers associated with the consumption of Nyaope in Butterworth, South Africa. This study adopted an explorative and descriptive qualitative approach that involved the facilitation of focus group discussions and one-on-one interviews with twenty-six participants. An analysis of the findings of the study revealed the health hazards associated with consuming Nyaope and the tendency of Nyaope consumption to induce hallucinations and delusions in young people. Moreover, the study showed that Nyaope stimulated mood swings among female adolescents, its consumption created a fertile ground for conflict, and the addiction to Nyaope led to the destruction of the future of female adolescents. The researchers recommend the application of multiple approaches to preventing the initiation of Nyaope consumption. These approaches include attempts to control the peddling of Nyaope in schools and communities as well as the introduction of pro-active educational interventions regarding the dangers of Nyaope on the part of relevant institutions and government.
New records of Pipistrellus kuhlii in Prague, Czech Republic (Chiroptera: Vespertilionidae)

Field: Agricultural and Biological Sciences (Life Sciences)

(Uploaded by Plazi for the Bat Literature Project) The paper presents three new findings of handicapped individuals of Pipistrellus kuhlii from the territory of the capital city of Prague in the years 2022 and 2023. All three individuals were admitted to the Wildlife Rescue Center in Prague. One find comes from the hibernation period, two finds come from the end of the summer period and the early period of autumn migrations. Two finds come from built-up areas, one find is from the outskirts of Prague. The probability of the existence of a maternity colony in central Bohemia is discussed.
Identity Politics in Central Asia and the Muslim World: Nationalism, Ethnicity and Labour in the Twentieth Century, ed. Willem van Schendel and Erik J. Zürcher, The Library of International Relations, London: I. B. Tauris, 2001, ISBN1-86064-261-6, 235 pp. $59.50.

Field: Social Sciences (Social Sciences)

Identity Politics in Central Asia and the Muslim World: Nationalism, Ethnicity and Labour in the Twentieth Century, ed. Willem van Schendel and Erik J. Zürcher, The Library of International Relations, London: I. B. Tauris, 2001, ISBN1-86064-261-6, 235 pp. $59.50. - Volume 36 Issue 1
Penyuluhan Pengaturan Diet pada Pasien Diabetes Mellitus di Puskesmas Tamalate

Field: Health Professions (Health Sciences)

Diabetes Mellitus (DM) is a chronic disease with a rising incidence in Indonesia. One important effort in controlling diabetes is proper dietary management, yet many patients still do not understand the principles of a diabetes diet. This community service activity aims to improve patient knowledge about diet management through counseling at the Tamalate Community Health Center. The implementation method included material delivery, discussion, healthy menu simulations, and pre- and post-test evaluations. The activity was held on August 23, 2025, with 35 diabetes patients participating. The evaluation results showed an increase in participant knowledge after the counseling session, as well as a positive response to the method used. The daily menu simulation was considered very helpful in helping participants understand the implementation of a diabetes diet. It can be concluded that this counseling session effectively increased patient knowledge about diet management. Follow-up in the form of ongoing nutritional support is needed to support patient behavior changes in diabetes management.
Simultaneous bilinguals who do not speak a tone language show enhancement in pitch sensitivity but not in executive function

Field: Psychology (Social Sciences)

Abstract Previous studies have reported perceptual advantages, such as when discriminating non-native linguistic or musical pitch differences, among first-year infants growing up in bilingual over monolingual environments. It is unclear whether such effects should be attributed to bilinguals’ enhanced perceptual sensitivity and/or cognitive abilities, and whether such effects would extend to adulthood. Twenty-four Dutch, 24 Dutch simultaneous bilingual (DSB), and 24 Chinese Mandarin speakers were examined by three sets of tasks assessing their linguistic pitch and music perception, executive function, as well as interactions across these modalities. Results showed degrees of advantages for DSB and Chinese participants’ over their Dutch peers in lexical tone discrimination and pitch-related music tasks. In tasks related to executive function, no difference was observed between DSB and Dutch participants, while Chinese participants’ performances were modulated by cognitive interference of language processing. Findings suggest that listeners’ enhanced sensitivity to linguistic and musical pitch may stem from acoustic (DSB) and experience (Chinese) rather than cognitive factors. Moreover, Dutch participants showed robust correlations between their linguistic and musical pitch perception, followed by limited correlations in DSB, and virtually no correlation among Chinese participants, illustrating how distinct language experiences can lead to specific pitch perception patterns between language and music.
On the Strong Stabilizability of MIMO n-Dimensional Linear Systems

Field: Mathematics (Physical Sciences)

A plant is strongly stabilizable if there exists a stable compensator to stabilize it. Based on some theorems in complex analysis of several variables proved in this paper, we present necessary conditions for the strong stabilizability of complex and real n-D multi-input multi-output (MIMO) shift-invariant linear plants. For the real case, the condition is a generalization of the parity interlacing property of Youla, Bongiorno, and Lu [ Automatica J. IFAC, 10 (1974), pp. 159--173] for the strong stabilizability of a real one-dimensional MIMO plant. These conditions are also sufficient for the cases of n-D plants with a single output (MISO) or with a single input (SIMO). For general n-D MIMO plants, we do not know if the conditions are sufficient or not. A useful sufficient, but not necessary, condition for the strong stabilizability of a class of n-D $(n\geq 2)$ MIMO plants is given.
Variation in Cytosine Methylation among Pecan Cultivars at Different Developmental Stages

Field: Agricultural and Biological Sciences (Life Sciences)

Cytosine methylation plays important roles in regulating gene expression and modulating agronomic traits. In this study, the fluorescence-labeled methylation-sensitive amplified polymorphism (F-MSAP) technique was used to study variation in cytosine methylation among seven pecan ( Carya illinoinensis ) cultivars at four developmental stages. In addition, phenotypic variations in the leaves of these seven cultivars were investigated. Using eight primer sets, 22,796 bands and 950 sites were detected in the pecan cultivars at four stages. Variation in cytosine methylation was observed among the pecan cultivars, with total methylation levels ranging from 51.18% to 56.58% and polymorphism rates of 82.29%, 81.73%, 78.64%, and 79.09% being recorded at the four stages. Sufficiently accompanying the polymorphism data, significant differences in phenotypic traits were also observed among the pecan cultivars, suggesting that cytosine methylation may be an important factor underlying phenotypic variation. Hypermethylation was the dominant type of methylation among the four types observed, and full methylation occurred at higher levels than did hemimethylation in the pecan genomes. Cluster analysis and principal coordinate analysis (PCoA) identified Dice coefficients ranging from 0.698 to 0.778, with an average coefficient of 0.735, and the variance contribution rates of the previous three principal coordinates were 19.6%, 19.0%, and 18.2%, respectively. Among the seven pecan cultivars, four groups were clearly classified based on a Dice coefficient of 0.75 and the previous three principal coordinates. Tracing dynamic changes in methylation status across stages revealed that methylation patterns changed at a larger proportion of CCGG sites from the 30% of final fruit-size (30%-FFS) stage to the 70%-FFS stage, with general decreases in the total methylation level, the rate of polymorphism, and specific sites being observed in each cultivar. These results demonstrated that the F-MSAP technique is a powerful tool for quantitatively detecting cytosine methylation in pecan genomes and provide a new perspective for studying many important life processes in pecan.
On the Warm Drawing of Copper Alloys (Study on Warm Working, 3rd Report)

Field: Materials Science (Physical Sciences)

To study on the effect of warm working on mechanical properties and electric conductivity for the age-hardenable copper alloys, 0.6%Cr-Cu alloy and 1.4%Cd-Cu alloy were worked to 90% reduction by drawing at room and elevated temperatures after solution treatment.The results obtained are as follows:(1) The wire drawn shows the highest value in hardness at the usual aging temperatures, that is, 500°C for Cr-Cu alloy and 250°C for Cd-Cu alloy.(2) The mechanical properties and electric conductivity of the wire drawn at the usual aging temperatures are compared with those of the wire cold drawn only and the wire aged after cold working. The warm drawn wire is the highest in tensile strength and electric conductivity.(3) The mechanism of strengthening due to the warm drawing may be attributed to the combined effect of the large amount of age and work-hardening.
Nursing Research & Subject Guide

Field: Nursing (Health Sciences)

This article was originally published in the UIC LHS Newsletter E-ppendix. The newsletter has been discontinued. The archive of this publication is found at: https://indigo.uic.edu/projects/E-ppendix_-_Online_newsletter_of_the_UIC_Library_of_the_Health_Sciences_Archives/142151. The TOC for all issues is at: https://indigo.uic.edu/articles/journal_contribution/E-ppendix_TOCs_all_issues/20146871
Optimization of Extraction Conditions from Gac Fruit and Utilization of Peel-Derived Biochar for Crystal Violet Dye Removal

Field: Environmental Science (Physical Sciences)

Gac fruit (Momordica cochinchinensis Spreng.) is a prominent source of carotenoids, renowned for its exceptional concentration of these compounds. This study focuses on optimizing the extraction of active components from the aril of gac fruit by evaluating the effects of extraction temperature, solid–liquid ratio, and extraction time. The primary objective is to maximize the yield of gac oil while assessing its antioxidant capacity. To analyze the kinetics of the solid–liquid extraction process, both first-order and second-order kinetic models were employed, with the second-order model providing the best fit for the experimental data. In addition, the potential of gac fruit peel as a precursor for biochar production was investigated through carbonization. The resultant biochars were evaluated for their efficacy in adsorbing crystal violet (CV) dye from aqueous solutions. The adsorption efficiency of the biochars was found to be dependent on the carbonization temperature, with the highest efficiency observed for BCMC550 (91.72%), followed by BCM450 (81.35%), BCMC350 (78.35%), and BCMC250 (54.43%). The adsorption isotherm data conformed well to the Langmuir isotherm model, indicating monolayer adsorption behavior. Moreover, the adsorption kinetics were best described by the pseudo-second-order model. These findings underscore the potential of gac fruit and its byproducts for diverse industrial and environmental applications, highlighting the dual benefits of optimizing gac oil extraction and utilizing the peel for effective dye removal.
En‘vision’ing Europe's crisis: Intertextuality in news coverage of the Eurozone crisis in Chinese, Indian and Russian press

Field: Social Sciences (Social Sciences)

European political communication studies are marked by a lack of attention to the visual. Yet there is a need to go beyond strictly textual analyses towards an understanding that visual images also play an important role in constructing a European Union (EU) identity both within and outside the Union's borders. This analysis explores the relationship between visual and textual imagery of the EU in international news discourses; a comprehensive intertextual approach which remains an under-researched perspective in studies of visual imagery in general. The study focuses on the intertextual imagery of the EU and its economic crisis in three ‘emerging’ powers; China, India and Russia. The three states are among the main poles in a multi-polar world – an emerging order characterized by power shifts and increased interdependence. In this new global design, the ‘emerging’ powers compete with the EU and USA, and contemplate their own responses to the EU's economic crisis, as well as calculate its effects. This study explores those responses as presented in the leading business papers of each country and asks how the relationship between the visual and textual imagery of the EU contributes to raising visibility and creating cognitive and emotional responses to its on-going crisis
Mate finding, dispersal, number released, and the success of biological control introductions

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract. An analysis of published data and a mathematical model of the population dynamics of introduced parasitoids were used to explore the possibility that biological control introductions fail because an Allee effect drives small, introduced populations extinct. Such an Allee effect would arise because low densities, resulting from dispersal into a new environment, lead to failure to mate, which leads to a male‐biased sex ratio, which, if extreme enough, could cause population extinction. For chalcidoids, ichneumonoids and tachinids, the proportion of parasitoid populations that established when introduced for control of lepidopteran pests increased with the number of parasitoids per release, the total number released, and the number collected when each variable was analysed separately. For chalcidoids alone, establishment increased with the number of releases for this variable analysed separately. However, stepwise logistic regression of establishment on these variables included only the total number released for chalcidoids and the number per release for ichneumonoids and tachinids. This suggests that an Allee effect may limit the establishment of introduced parasitoids more than stochastic environmental variation or lack of genetic variation. A reaction‐diffusion model of parasitoid introductions was developed, which included mate finding, dispersal, reproduction and survival. Sensitivity analysis showed that the critical number of females needed to establish a population decreased hyperbolically as mate detection distance and net reproductive rate were increased, but the critical number increased linearly as mean‐square displacement was increased. The critical number of females did not change when the gross distance traversed per generation was varied. This was because increased area searched by males compensated for increased displacement. Changing from virgin females producing all males (arrhenotoky) to virgin females producing no progeny increased the critical number of females by over 30%. The analysis of past introductions and the sensitivity analysis of the reaction‐diffusion model both suggested a threshold of about 1000 insects per release to ensure establishment of introduced parasitoids. The implications of our results for the design of biological control introductions are discussed. Limitations in retrospective analyses and current knowledge indicate the need for an experimental approach to introductions.
The Incidence of, and Patterns of Antibiotic Resistance among Culture-Proven Bacterial Neonatal Sepsis in Developing Countries

Field: Medicine (Health Sciences)

Abstract Aim: The menace of antimicrobial resistance, especially in neonatal sepsis, is growing at an alarming rate. The situation is aggravated more in developing countries; it is estimated that neonatal infection incidence ranges from 5.5 -170 cases /1,000 live births for blood culture-proven infections in developed. Also, it is estimated neonatal sepsis account for approximately 50% of neonatal deaths in developing countries. This systematic review aims to look at studies describing antibiotic resistance in positive blood cultures among neonatal populations in developing countries. Methods: The author searched Two major scientific databases (Ovid Medline & Embase), and other WHO regional online sites. The search was initially conducted on April 1, 2019, and repeated on June 11, 2020. Studies were included if they defined how sepsis cases were diagnosed or identified and provided information about the total number of blood cultures obtained, the number of bacterial isolates with details, and the number of patients enrolled. Only studies that complied with the minimum requirements for data inclusiveness described in the inclusion criteria were included. Results: The total sample size was 4,490 neonates with suspected sepsis that were analyzed in seven selected studies from the first search. The positive culture percentage was 45.3%; the predominant organisms were gram-negative with 76.1% of the total positive cultures The mean resistance rate was 37.8% for all tested antibiotics. In general, the highest resistance rate were for amoxicillin (69.1%), ceftazidime (72.0%), ampicillin (74.6%), aztreonam (76.9%) and clarithromycin (83.2%), with the lowest being for linezolid (0.0%), meropenem (4.3%), ampicillin/sulbactam (4.8%), rifampicin (5.0%), Cefepime (7.7%), and imipenem (8.4%). As for antibiotics resistance analyzed in the second search, all four papers revealed a high percentage resistance against most commonly used antibiotics (amoxicillin, ampicillin, and gentamicin) Conclusion: The presented data only views bacterial AMR rates in developing countries, which raises particular concern about the high level of resistance reported among gram-negative pathogens, especially Klebsiella and E. coli to gentamicin, ampicillin to third-generation cephalosporins. The implication of this search for clinical practice is crucial. Rigorous clinical and epidemiological surveillance based on proficient and inexpensive microbiology is required to deliver precise data on AMR, which, in turn, can enable the updating of local treatment guidelines and antibiotic stewardship programs.