jimnoneill/paper-to-field-training huggingface dataset:
Impact of sludge mechanical behaviour on spatial distribution parameters obtained with centrifugal spreader: Preliminary study

Field: Engineering (Physical Sciences)

Abstract In France, more than half of the production of sewage sludge is spread on agricultural fields as a fertilizer. However, these biosolids contain nutrients that can pollute the soil if their distribution on field is heterogeneous: it is then necessary to optimize the spreading in order to limit their environmental impacts. In that purpose, this study focuses on the impact of pasty materials rheological behaviour on spatial distribution parameters obtained with a centrifugal spreader, i.e. a spinning disc system. Kaolin suspensions were employed. To model their rheological properties, a Herschel–Bulkley equation was used, which is consistent with the literature. Experiments were performed with a specific spreading device (a vane with no disc) and with the CEMOB, a bench dedicated to the analysis of organic fertilisers spreading. Results showed that radial distribution of the 3D spread patterns is clearly dependent on the size and the density of the particles, both of them being related to the material consistency. Angular distribution also tends to follow similar tendencies. Eventually, advanced imaging shows a relation between fragmentation process and material consistency. This study presents a new approach to analyse organic spreading and opens the way to more developments.
Analysis of Employee Performance Through The Role of Knowledge Sharing and Competence With Commitment as Intervening Variables

Field: Business, Management and Accounting (Social Sciences)

The primary objective of this analysis is to ascertain the influence of information sharing and competency on employee performance within the context of the Department of Public Works and Highways Water Resources in Sidoarjo Regency. The study's target population consists of individuals employed in general or executive functional roles. The sample methodology utilised in this study involves the use of non-probability sampling, specifically employing a purposive sampling technique. The sample consisted of a total of 77 individuals. The data was derived from primary sources. Simultaneously, the study employs the Partial Least Squares (PLS) method. The findings of the study suggest that there is a noteworthy positive relationship between knowledge sharing and commitment. Conversely, competence is found to have a significant negative influence on commitment. Additionally, knowledge sharing is found to have a positive impact on employee performance, while competence does not have a significant effect on employee performance. Moreover, commitment is found to have a positive influence on employee performance. Furthermore, commitment is identified as a mediating factor in the relationship between knowledge sharing and employee performance, but it does not mediate the effect of competence on employee performance.
Expressed Sequence Tags (ESTs) from a Jute (<i>Corchorus olitorius</i>) cDNA Library

Field: Agricultural and Biological Sciences (Life Sciences)

Analysis of the genome of jute (Corchorus olitorius) was done by creating a new cDNA library of expressed sequence tags (ESTs) in pBluescript as the previous libraries reported earlier in this journal yielded only small DNA fragments from chloroplast and mitochondrial DNA. This report discusses results from a cDNA library constructed using poly A+ mRNA purified from 7-day old etiolated jute seedlings. Out of 700 recombinant plasmids obtained, 250 were analyzed using WU-BLAST (www.arabidopsis.org) for similar EST sequences in Arabidopsis thaliana and other higher plants. So far the analysis of the library has yielded several significant sequences, including the complete open reading frame of the 60S acidic ribosomal protein P3 and a partial cDNA of Class I chitinase. These results and future EST sequences from this library will be made available in Genbank and the sequence information will be used to clone full length DNA through PCR. Â DOI = 10.3329/ptcb.v16i2.1110Plant Tissue Cult. & Biotech. 16(2): 95-104, 2006 (December)
The prognostic relevance of 14-3-3 expression in cancers: a meta-analysis

Field: Medicine (Health Sciences)

AbstractObjective: A number of recent clinical studies have identified a relationship between elevated expressions of 14-3-3 and poorer patient prognosis in the context of several cancers. The present meta-analysis was therefore conducted to gain an enhanced understanding of the prognostic importance of 14-3-3 levels in cancer patients. Methods: Two reviewers independently systematically reviewed the Web of Science, Embase, and PubMed databases to identify published, suitable studies through October 2019. The correlation between the level of 14-3-3 and cancer patient survival were assessed based upon pooled HR (hazard ratios) and 95% CI (confidence intervals) derived from chosen studies. Results: In total we were able to identify 22 eligible studies that had enrolled 2676 patients in the present meta-analysis. Assessment of these studies revealed that elevated 14-3-3 level correlated significantly with poorer OS (overall survival) (HR : 1.93, 95% CI : 1.42-2.61) in cancer patients. This was true even when studies were analyzed in subgroups according to tumor type, sample size, analysis type, and method of HR determination. With respect to disease-free survival (DFS), the pooled HR for cancer patients expressing high levels of 14-3-3 was 1.89 (95% CI: 1.56-2.30). Patients with elevated 14-3-3 expression also exhibited reduced CSS (cancer-specific survival) (HR: 3.47, 95% CI: 2.12-5.69).Conclusions: The outcomes indicate that higher level of 14-3-3 correlates with poorer patient prognosis in a range of cancer types.Keywords: Meta-analysis, Prognosis, 14-3-3 Proteins C Continuous...
Maximum power extraction on wind turbine systems using block‐backstepping with gradient dynamics control

Field: Engineering (Physical Sciences)

Summary In this work, a novel adaptive control scheme that allows driving a stand‐alone variable‐speed wind turbine system to its maximum power point is presented. The scheme is based on the regulation of the optimal rotor speed point of the wind turbine. In order to compute the rotor speed reference, a model‐based extremum‐seeking algorithm is derived. The wind speed signal is necessary to calculate this reference, and a novel artificial neural network is derived to approximate this signal. The neural network does not need off‐line learning stage, because a nonlinear dynamics for the weight vector is proposed. A block‐backstepping controller is derived to stabilize and to drive the system to the optimal power point; to avoid singularities, the gradient dynamics technique is applied to this controller. Numerical simulations are carried out to show the performance of the controller and the estimator. Copyright © 2016 John Wiley & Sons, Ltd.
Transition from the vortex state to the Fulde–Ferrell–Larkin–Ovchinnikov state in quasi-two-dimensional superconductors

Field: Physics and Astronomy (Physical Sciences)

We examine the coexistence of the vortex state and the\nFulde-Ferrell-Larkin-Ovchinnikov (FFLO) state in quasi-two-dimensional type-II\nsuperconductors and the crossover from the coexistence state to the pure FFLO\nstate when the Maki parameter \\alpha increases. The pure FFLO state,\ncharacterized by finite center-of-mass momenta q \\ne 0 of Cooper pairs occurs\nin the two-dimensional limit, when the magnetic field is parallel to the\nconductive plane. The vectors q are determined from the Fermi-surface structure\nand pairing anisotropy, and become finite below a temperature T^*. In\nquasi-two-dimensions, because of the orbital pair-breaking effect, the\ncoexistence state characterized by (n,q//) occurs, where n and q// denote the\nLandau level index of the vortex state and the wave number of the additional\nFFLO modulation along the magnetic field. We obtain the \\alpha dependence of\nthe upper critical field by numerical calculations. The upper critical field\nexhibits a cascade curve in the H-T phase diagram. It is analytically shown\nthat n diverges in the two-dimensional limit \\alpha \\to \\infty below T^*. In\nthis limit, the upper critical field equation of the coexistence state is\nreduced to that of the FFLO state. A relation between n of the coexistence\nstate and q_{\\perp} of the pure FFLO state is obtained, where q_{\\perp} denotes\nthe component of q perpendicular to the magnetic field. It is found that the\npure FFLO state is nothing but the vortex state with infinitely large n as is\nknown in two-dimensional superconductors in a tilted magnetic field. The vortex\nstate with large n can be regarded as the FFLO state with non-zero q_{\\perp} in\nthree dimensions.\n
Erythropoietin as treatment of haemodialysis-related porphyria cutanea tarda

Field: Medicine (Health Sciences)

Erythropoietin as treatment of haemodialysis-related porphyria cutanea tarda V. Piazza, V. Piazza 1Divisione di Nefrologia ed EmodialisiPavia, Italy Valter Piazza MD, Divisione di Nefrologia ed Emodialisi, Fondazione Clinica del Lavoro, v. Boezio 26, 27100 Pavia, taly Search for other works by this author on: Oxford Academic PubMed Google Scholar G. Villa, G. Villa 1Divisione di Nefrologia ed EmodialisiPavia, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar F. Galli, F. Galli 1Divisione di Nefrologia ed EmodialisiPavia, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar S. Segagni, S. Segagni 1Divisione di Nefrologia ed EmodialisiPavia, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar G. Bovio, G. Bovio 1Divisione di Nefrologia ed EmodialisiPavia, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar F. Poggio, F. Poggio 1Divisione di Nefrologia ed EmodialisiPavia, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar Loredana Picardi, Loredana Picardi 1Divisione di Nefrologia ed EmodialisiPavia, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar Laura Bianco, Laura Bianco 2Servizio di Analisi Chimico Cliniche, Fondazione Chnica del LavoroPavia, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar A. Salvadeo, A. Salvadeo 1Divisione di Nefrologia ed EmodialisiPavia, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar G. Barosi G. Barosi 3Clinica Medica II, IRCCS Policlinico S. MatteoPavia, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar Nephrology Dialysis Transplantation, Volume 7, Issue 5, 1992, Pages 438–442, https://doi.org/10.1093/oxfordjournals.ndt.a092163 Published: 01 January 1992 Article history Received: 10 April 1991 Revision received: 16 October 1991 Published: 01 January 1992
Rubia yunnanensis Diels

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Rubia yunnanensis Diels (Rubiaceae) is an important medicinal plant in Yunnan Province, China. Its roots and rhizomes are named Xiaohongshen as a local herb in Yunnan. Three types of the main chemical constituents, i.e. cyclopeptides, quinones, and triterpenes, with various bioactivities, particularly potential anti-tumor activity, have been found in this plant. Herein the botany, ethnopharmacology, phytochemistry, and biological activities of Rubia yunnanensis will be reviewed.
Screening of Bioactive Compounds and Potential Drug Targets for Cirrhosis Associated Cardiac Hypertrophy

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Background and Objective: Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, claiming the lives of an estimated 17.9 million people per year.Synthetic medicines are prone to toxicity and long-term side effects.Herbal medicine, on the other hand, is typically directed towards assisting the body's natural healing process and can decrease toxicity and increase therapeutic benefits.The objective of study is to quantitatively analyze the bioactive compounds of Solanum album and Solanum nigrum and in silico analysis to identify the protection pathway of cardiac tissues against cirrhosis-related cardiac hypertrophy using selected herbal compounds.Materials and Methods: Crude extracts were prepared with methanol, ethanol, hexane and chloroform solvents by extraction technique (Maceration method).Phytochemical analysis was carried out with a confirmatory test through TLC for terpenoids, alkaloids, flavonoids, phenols and tannins.Plant extracts of Solanum album and Solanum nigrum are characterized by UV-Vis Spectrophotometer (UV) and Fourier-Transform Infrared Spectroscopy (FTIR).In silico molecular docking with RCSB Protein Data Bank is used to get the three-dimensional structures of AGTR1 (PDB101) and PLC (PDB101).Ligand selection is done with the help of Pub Chem Target and ligand optimization is done by Drug Discovery Studio version 21.1.0software and PYMOL 4.6.0used for molecular docking analysis.Results: In vitro studies revealed that methanolic and ethanolic extracts of Solanum nigrum and Solanum album are rich sources of active secondary metabolites.Percentage inhibition against standard (ascorbic acid) showed that herbal extracts have excellent radical scavenging activity.The FTIR spectra of Solanum nigrum and Solanum album extracts showed peaks at 3323 and 3685 cmG 1 due to stretching of OH group.The IC 50 value of 81.746 µg/mL for Solanum nigrum and 74.048 µg/mL for Solanum album is reported.In silico studies highlights that Quercetin has binding energies of -8.4 kcal/mol compared to Angiotensin II (-7.5 kcal/mol) and Phosphatidylinositol 4,5 bisphosphate (-7.3 kcal/mol) with strong molecular binding action mechanism as compared to the conventional drugs.Conclusion: The plant extracts and their components have shown excellent antioxidant activities, in silico results of the study need in vivo pharmacological experiments for further verification to significantly improve the efficiency of compounds under study.
Interstitial deletion of bands 4q12-->q13.1: case report and review of proximal 4q deletions.

Field: Medicine (Health Sciences)

We report a 6 year old child with a small de novo interstitial deletion of proximal 4q, karyotype 46,XX,del(4)(pter-->q12::q13.1-->qter). She has made good developmental progress and attends normal school with minimal assistance. We review published reports and clinical findings in patients with proximal 4q deletions.
Tournament and non-tournament anglers have little effect on a largemouth bass population compared to natural mortality

Field: Agricultural and Biological Sciences (Life Sciences)

Popularity of bass (Micropterus spp.) catch and release and tournament angling during the past decade has resulted in increased potential for these activities to induce population level effects. Understanding capture rates and mortality sources relative to total population mortality is essential to focus of management. We conducted monthly electrofishing, solicited non-tournament angler tag returns, and censused largemouth bass (Micropterus salmoides) tournaments at Brushy Creek Lake, Iowa, USA, from April 2015 to June 2018. We used a multistate mark–recapture model to evaluate the effects of air temperature, water temperature, tournament bass per angler, and tournament initial mortality on non-tournament and tournament angler capture probability and natural, non-tournament angling, and initial and delayed tournament mortality. Average total annual mortality was 0.66 with natural mortality representing the largest mortality source (0.57) followed by delayed tournament mortality (0.06), non-tournament angling mortality (0.02), and initial tournament mortality (0.006). Our results reveal both non-tournament and tournament angling mortality are low compared to natural mortality in some lakes. Therefore, cumulative angling mortality likely has minimal population level effects on some bass populations.
How laws of universal design discriminate between different types of disabilities - Lessons learned from Norway

Field: Social Sciences (Social Sciences)

Different diseases and disabilities have varying levels of prestige in the society. Is this variance also visible in the legal documents about universal design in the transport sector? Based on a document analysis of 42 legal documents and guidelines in Norway, we have examined (1) how the laws define universal design and (2) what groups they include when talking about disabilities. Both a qualitative and a quantitative analyses are conducted to answer the research question: do the legal documents discriminate between different types of disabilities – and if this is the case, is this due to difference in prestige or visibility? Findings suggest that there is a biased focus on physical environment in the definitions of universal design and that visible disabilities, especially mobility impairments and visual impairments, are prioritized over other types of disabilities. Disease prestige does not seem to explain the difference in terms of inclusion in legal documents to the extent that visibility does.
Cancer treatment with hormone therapy and its relationship with xerostomia and hyposalivation

Field: Medicine (Health Sciences)

Abstract Background: The appearance of new drugs for cancer treatment has increased patient survival but it has also brought adverse effects, such as the sensation of dry mouth and hyposalivation. Objective: To assess the relationship of using hormone therapy in breast and prostate cancer patients and the occurrence of xerostomia and hyposalivation. Method : Cross-sectional study with 114 patients diagnosed with cancer and treated with hormone therapy (anastrozole or bicalutamide). Age, type of neoplasia, sex, presence of xerostomia (yes or no), and type of medication were obtained with a questionnaire. The researcher collected resting and stimulated salivary flows in the morning. The descriptive statistic analysis, chi-square test (p<0.005), and t-test (<0.005) were performed using the Statistical Package for Social Science™ (SSPS), version 21, for different variables of hyposalivation and hormone therapy. Results : The results showed that 67 (55.8%) patients using hormone therapy drugs presented hyposalivation and 73 (64%) patients presented xerostomia. Conclusion : According to the results of this study, there is a positive association between stimulated hyposalivation and the use of hormone therapy drugs (p = 0.015). There was also a positive association between hyposalivation and xerostomia and the use of hormone therapy drugs (p = 0.049 and p = 0.001).
Coleridge in Lilliput: The quality of parliamentary reporting in 1800

Field: Arts and Humanities (Social Sciences)

Coleridge reported three speeches in 1800 for the London Morning Post. His notes and printed reports are collated with all other independent reports, and some simple rules of textual analysis are formulated for evaluating the authenticity of parliamentary reports. A distinction between the scarce but more authentic shorthand or authorial texts and the usual newspaper texts is demonstrated. Yet it is found that a small but significant sprinkling of the salient expressions of the original speakers can be recovered even from newspaper reports. The historical scholar, armed with the method here presented, need not turn with indiscriminate suspicion from all the unsifted ore in the collections of Debrett, Cobbett, or Hansard. As for Coleridge, his three reports represent three degrees of originality. In general he was, as a reporter, simultaneously more faithful and more creative than his professional colleagues.
Supplementary Material for: Association between Rapid Ventricular Response and Stroke outcomes in Atrial fibrillation related Cardiac embolic stroke

Field: Medicine (Health Sciences)

Introduction: Patients with atrial fibrillation related stroke (AF-stroke) are prone to developing rapid ventricular response (RVR). We investigated whether RVR is associated with initial stroke severity, early neurological deterioration (END) and poor outcome at 3 months. Methods: We reviewed patients who had AF-stroke between January 2017 and March 2022. RVR was defined as having heart rate>100 beats per minute on initial electrocardiogram. Neurological deficit was evaluated with National Institutes of Health Stroke Scale (NIHSS) score at admission. END was defined as increase of ≥2 in total NIHSS score or ≥1 in motor NIHSS score within first 72h. Functional outcome was score on modified Rankin Scale at 3 months. Mediation analysis was performed to examine potential causal chain in which initial stroke severity may mediate relationship between RVR and functional outcome. Results: We studied 568 AF-stroke patients, among whom 86 (15.1%) had RVR. Patients with RVR had higher initial NIHSS score (p<0.001) and poor outcome at 3 months (p=0.004) than those without RVR. The presence of RVR [Adjusted Odds ratio (aOR)=2.13; p=0.013] was associated with initial stroke severity, but not with END and functional outcome. Otherwise, initial stroke severity [aOR=1.27; p=<0.001] was significantly associated with functional outcome. Initial stroke severity as a mediator explained 58% of relationship between RVR and poor outcome at 3 months. Conclusion: In patients with AF-stroke, RVR was independently associated with initial stroke severity but not with END and functional outcome. Initial stroke severity mediated considerable proportion of association between RVR and functional outcome.
Gender Differences in Misdiagnosis and Delayed Diagnosis among Adults with Autism Spectrum Disorder with No Language or Intellectual Disability

Field: Medicine (Health Sciences)

Autism Spectrum Disorder (ASD) is often unrecognized, especially in mild forms and in women. Studies evaluating features associated with missed/misdiagnosis in men and women with ASD are warranted. 61 subjects (22 females, 39 males, age 28.5 ± 10.8 years) with ASD with no language/intellectual deficit were enrolled in the service for the treatment of psychiatric comorbidities in adults with ASD of the ASST Fatebenefratelli-Sacco in Milan (Italy). A detailed clinical history was gathered, and two self-report questionnaires (Autism Spectrum Quotient-AQ and Adult Autism Subthreshold Spectrum-AdAS Spectrum) were administered. 75.4% received their ASD diagnosis average eight years later than the first evaluation by mental health services. Compared to males, females showed a significantly greater delay in referral to mental health services and a significantly higher age at diagnosis of ASD. Among men, diagnostic delay inversely correlated with scores on the AdAS Spectrum total, Verbal communication, Empathy and Inflexibility and adherence to routine domains. Among women, diagnostic delay positively correlated with the Attention to detail score while the age at diagnosis of ASD positively correlated with the AdAS Spectrum Verbal communication and Restricted interests and rumination domain scores. Females were less likely to be correctly diagnosed and more likely to be misdiagnosed at first evaluation than men. Females reported significantly higher scores than men in the Hyper/Hyporeactivity to sensory input domain only among subjects who were misdiagnosed. Our findings provide gender-specific information about ASD patients seeking help for comorbid conditions and might be a primary ground for future research.