jimnoneill/paper-to-field-training huggingface dataset:
CARDIORESPIRATORY RESPONSES TO ISOKINETIC EXERCISE IN PATIENTS WITH CORONARY ARTERY DISEASE

Field: Medicine (Health Sciences)

ABSTRACT Introduction Exercise training using an isokinetic dynamometer is an alternative for improving muscle strength in patients with coronary artery disease (CAD). Few studies have shown metabolic and cardiorespiratory responses to submaximal isokinetic exercises in patients in cardiac rehabilitation programs. Objective To describe cardiorespiratory responses at two intensities of isokinetic exercise. Additionally, we compared the cardiorespiratory responses of isokinetic exercise with data from the incremental cardiopulmonary exercise test (CPET). Methods Eight individuals with CAD (61.7 ± 6.6 years) performed the following tests: 1) CPET on a treadmill; 2) Peak torque test (five repetitions) and fatigue resistance test (20 repetitions) of knee flexion-extension at angular speeds of 120°/s and 180°/s; 3) Two sets of 20 repetitions were performed at 30–40% (low-intensity, LI) and 50–60% (moderate-intensity, MI) of peak torque at angular speeds of 120°/s and 180°/s, using an isokinetic dynamometer. During the exercises, the individuals were connected to an expired gases analyzer with simultaneous monitoring of the electrocardiogram trace, heart rate (HR), oxygen consumption (VO2), carbon dioxide production, and minute ventilation (VE). The differences (∆) between the peak measurements during exercises and the baseline values were calculated. Results Both LI and MI produced cardiorespiratory responses below the anaerobic threshold (82.8 ± 8.1% of HRmax and 74.4 ± 9.6% of VO2peak) compared to the CPET data ( P < 0.01). MI showed higher ∆ HR (9.8 ± 5.5 vs. 6.3 ± 4.6 bpm; P = 0.01), ∆ rate pressure product (3015 ± 2286 vs. 1957 ± 1932 mmHg·bpm; P = 0.01), and ∆VE (10.2 ± 6.2 vs. 6.9 ± 7 L·min-1; P = 0.03) than LI at the angular velocity of 180°/s. Conclusion These results suggest that this isokinetic exercise protocol may be used as a strategy for cardiac rehabilitation programs in patients with CAD. Level of evidence IV; Case series.
E-portfolio as physics learning assessment

Field: Social Sciences (Social Sciences)

One of the technologies available to support the assessment process is the e-portfolio. Much research has been done for e-portfolio assessment, and the result can easily find the result in journals. Even though systematic study about e-portfolio as physics learning assessment still rarely done. This research aims to identify the role of e-portfolio as a physics learning assessment in school. A literature study is carried out using four procedures based on PRISMA that are (1) identification, (2) screening, (3) eligibility, and (4) included. Article search has been done through the DOAJ, ERIC, IOP Science, Science Direct, and Springer Link. Based on analysis results, the use of e-portfolio encourages the creation of self-regulation learning. Furthermore, self-regulation learning can help develop a metacognitive skill that students much need for learning physics. Even so, based on 220 articles identified, research about e-portfolio as physics learning assessment has not been found. Therefore, further research is needed to develop and implement an e-portfolio as a physics learning assessment.
Proton irradiation effects on InGaAs/InAsSb mid-wave barrier infrared detectors

Field: Physics and Astronomy (Physical Sciences)

Semiconductor-based mid-wave infrared photon detectors that functionalize space-based imaging systems are susceptible to both cumulative ionization and displacement damage, especially due to proton irradiation. Here, the dark current density and quantum efficiency of a mid-wave infrared detector utilizing a strain-balanced InGaAs/InAsSb superlattice active region are examined as a function of a 63 MeV proton radiation dose. Proton-irradiation is performed in an incremental stepwise dose up to a total ionizing dose of 100 krad(Si) or an equivalent proton fluence of 6.1 × 1011 protons/cm2. All characterization work is conducted with the detectors held at an operating temperature of 130 K throughout the experiment to limit thermal annealing effects. Prior to irradiation, the quantum efficiency of the top-side illuminated device without anti-reflection coating is 59.5%. The quantum efficiency is largely independent of temperature below 150 K, indicative of an electron minority carrier. As irradiation progressed the typical linear increase in inverse quantum efficiency with increasing proton fluence was observed, which led to a quantum efficiency damage factor of 1.12 × 1013 e cm2/ph. This value is shown to be an order of magnitude lower than typically observed in III-V nBn devices and is likely due to the higher mobility of minority electrons in the active region of this device. A full analysis of the characterization results suggests that displacement damage creates a significant population of donor states that modify the doping profile, in addition to Shockley–Read–Hall recombination centers that generally form as a result of proton irradiation.
Omega 3/6 ratios: Usage and epigenetic changes in health and Alzheimer's disease

Field: Medicine (Health Sciences)

Abstract Background From our previous research, we identified circulating metabolites that are associated with cognitive performance and dementia including polyunsaturated fatty acids (PUFA), in particular plasma levels of Omega‐3. To follow up on this finding, we sought to explore potential mechanism mediating the effect of Omega‐3 and Omega‐6 on these neurodegenerative phenotypes. Herein, we hypothesized that modulation of immune response and inflammation may mediate the effect of PUFA on neurodegenerative diseases. Methods 1.Validate our PUFA ratios hypothesis on the MAPT intervention study. 2.Evaluate the epigenetic mechanisms modulation derived from genetics using genome‐wide association studies. 3.Corroborate previous results on real methylation data from the DELCODE study using the EPIC array. 4.Evaluate the biological age derived by epigenetics and its implications in healthy and cognitively affected subjects. Results The effect of the PUFA ratios follows the same trend on the MAPT study as previously described during our first period. We observed that the methylation of the genes coding for key enzymes of PUFA metabolism is modulated by levels of Omega‐3. Likewise, these methylation changes have been described in susceptibility genes for Alzheimer’s disease (AD) that modulate immune response. Finally, methylated signals also enabled the prediction of biological age. We observed that biological age in DELCODE participants differs from chronological age depending on the status of the participants. Conclusions The present analysis suggests that PUFA ratios are associated with cognitive decline as we previously described. Moreover, we suggest that genetic signals located in the immune‐related gene cluster MS4A are modulated by changes in DNA methylation. The same epigenetic modulation seems to mediate the genetic effect discovered in the sTREM2 GWAS. Interestingly, methylation modulation in MS4A gene has been previously reported using an independent approach. Likewise, TREM2 locus seems to be affected by methylation changes. Finally, our methylation data allowed us to analyze the biological age of cognitively affected individuals and find some clear differences with their chronological ages. Using our results, we will explore whether PUFA levels, and the ratio built on Omega‐6 and Omega‐3, modulate levels of CSF sTREM2 offering thereby a potential connection between PUFA levels and neuroinflammation in the context of AD.
Optimization of Extraction Process of Huangqi Guizhi Wuwutang by Orthogonal Design

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective:To optimize the extraction technology of Huangqi Guizhi Wuwutang.Method:The content of astragaloside and paeoniflori were determined by HPLC.The optimum extraction condition was investigated by orthogonal design;the content of astragaloside,paeoniflorin and the ratio of dry extraction were regarded as the detection index.Result:The optimum extraction was as follows: soaking in ten times amount of water for half an hour,extracting three times,every time for one and a half hour.Conclusion: The optimum technology was stable and feasible for the extraction of Huangqi Guizhi Wuwutang.
Portland Cement-Residues-Polymers Composites and Its Application to the Hollow Blocks Manufacturing

Field: Engineering (Physical Sciences)

Agricultural wastes and sawdust combined with cement matrix in the manufacture of building elements has been practiced with success in developed countries. In this study, sawdust from wood species (Pinus caribaea and Eucalyptus grandis) and an agricultural waste—rice husk (Oriza sativa) were combined with Portland cement type V (high initial strength), modified by polymer styrene-butadiene (SBR) addition. Hollow blocks produced with Eucalyptus grandis and rice husk residues showed better compressive strength; however, those produced with residues derived from Pinus caribaea presented non-satisfactory results, due to the particle size that was used.
Repressors' and Sensitizers' Affective Change during Free Association

Field: Psychology (Social Sciences)

Repressors, sensitizers, and a control group free-associated to threatening and nonthreatening stimuli for time periods ranging from 1 to 40 sec., giving ratings of affective states after each response period. In spite of the fact that sensitizers showed greater “approach” responding, they did not reduce their anxiety levels. The evidence suggests the need to reevaluate the presumed anxiety-reducing function of sensitizing behaviors.
Successive superposition: a technique for the exact modeling of deterministic packet queuing networks

Field: Computer Science (Physical Sciences)

This paper provides a methodology to decompose a complex network, containing primarily deterministic traffic, into isolated /spl Sigma/D/sub i//D/1 queuing models. We then present a new technique, Successive Superposition, to analyze the resulting models. In a /spl Sigma/D/sub i//D/1 queuing system, multiple streams of different bit rate, but constant length packets, arrive at a single high-speed multiplexer. Because of its application to Asynchronous Transfer Mode (ATM) switching nodes, previous /spl Sigma/D/sub i//D/1 analyses have assumed that stream arrivals are randomly staggered, and packets are served on a first-come-first-served basis. This work was, however, inspired primarily by the need for the accurate assessment of interprocessor communication costs in compile-time multiprocessor scheduling applications. For these applications, streams typically have known arrival times and must often be prioritized. This paper applies primarily to the class of digital signal processing and other application which can be represented by directed, acyclic precedence graphs. The analysis presented in this paper provides an exact characterization of the traffic, including service start times, queue sizes, and system departure times. We confirm the validity of our approach against simulation results. Finally, we demonstrate the utility of this work in a compile-time multiprocessor scheduling application.
Dose-adjusted Plasma Concentrations of Sublingual Buprenorphine are Lower During than After Pregnancy

Field: Medicine (Health Sciences)

( Am J Obstet Gynecol . 2017;216(1):64.e1–64.e7) Buprenorphine is increasingly used in pregnant women with opioid use disorders, as it has recently been associated with less severe neonatal complications and comparable efficacy as methadone. Currently, dosing of buprenorphine for pregnant women is based on recommendations for nonpregnant patients; however, drug absorption and metabolism can be impacted by pregnancy. This study examined the pharmacokinetic properties of sublingual buprenorphine in pregnant women and the postpartum period.
Investigating the effect of Zr content on electrochemical and tribological properties of newly developed near β-type Ti-alloys (Ti–25Nb-xZr) for biomedical applications

Field: Materials Science (Physical Sciences)

In order to create alloys with exceptional properties for orthopedic uses, this study focuses on the impact of zirconium (Zr) content on the structural, electrochemical, and tribological qualities of nanostructured Ti–25NbxZr [x = 5, 10, 15, 20, 25, and 30 atomic (at.) %] alloys. The structural evolution was investigated using XRD and SEM techniques. The mechanical characteristics of the produced alloys, including Vickers hardness and Young’s modulus, were measured. In addition, the corrosion tests were performed using the OCP, EIS, and PD methods in Ringer’s solution within the independent pH range at 37°C. A ball-on-disc tribometer was used to investigate the tribological behavior of the alloys under various loads and wet conditions using the Ringer solution. It has been verified that Zr content (at. %) in the alloys had an impact on their morphologies, structural evolution, and mechanical characteristics. According to the morphological analysis, the particle and crystallite size decreases with increasing Zr content. Young’s modulus and Vickers hardness show the same tendency. The EIS data demonstrated that a single passive film formed on the alloy surfaces, and the addition of Zr enhanced the corrosion resistance of the passive films. The polarization curves demonstrate that the alloys had low corrosion current densities and large passive areas without the passive films disintegrating. Likewise, the inclusion of Zr resulted in a reduction in the corrosion and passive current density values. All of these results suggested that the titanium alloys exhibit a more noble electrochemical activity caused by Zr. From the tribological perspective, it was found that the friction coefficient of the alloys reduced with increasing Zr content.
IMPLEMENTATION OF FLIPPED CLASSROOM STRATEGY IN MATHEMATICS LEARNING TO STUDENTS’ COGNITIVE SKILL

Field: Social Sciences (Social Sciences)

New learning paradigm demands change of teachers’ role in learning process mainly as facilitator, team based work, and use of education technology. Flipped classroom strategy is an alternative means of improving students’ cognitive skill in mathematics learning. Flipped classroom strategy is in line with new paradigm of mathematics learning based on constructivism. The aim of research is to know the influence of flipped classroom strategy toward students’ cognitive skills and learning activity. This research uses experiment method. A limited experiment done in a classroom of Senior High School indicates that Flipped classroom gives positive result toward the students’ cognitive skill and learning activity in mathematics learning compared to the control group. \nKeywords : Flipped slassroom strategy, cognitive skill, and learning activity.
Fracture strengths of ceramic brackets subjected to mesial-distal archwire tipping forces.

Field: Dentistry (Health Sciences)

This study tested the strength of ceramic orthodontic brackets subjected to mesial-distal tipping forces on five types of preadjusted, maxillary right central incisor ceramic twin brackets for both 0.018" and 0.022" slot sizes. Description of each bracket was by manufacturer's abbreviation-crystallinity-slot bracket, eg., AL-P-18, meaning Allure-polycrystalline-0.018" slot bracket. Thirty brackets of each type were used for a total of 300 brackets, each bonded to a porcelain denture tooth. A special apparatus was designed to hold the denture tooth, the wire, and the bracket in a standard position while an Instron machine applied a tipping force to the full size rectangular archwire at a distance of 7.0 mm lateral to the center of the bracket. The tipping force was applied until the bracket fractured. The fracture force, fracture angle, and fracture location were recorded. High fracture force values tended to accompany large fracture angles while low fracture force values tended to be associated with small fracture angles. The clinical significance was that the stronger ceramic brackets can be expected to withstand larger amounts of archwire tipping adjustments prior to bracket fracture. With the literature indicating the optimum force for tipping of maxillary incisors to be from 50 to 125 g, all the brackets are sufficiently strong to consistently withstand the suggested magnitude of archwire tipping forces. However, if excessive tipping forces were required by the clinician, ceramic brackets would be prone to fracture.
The Case of Fuller vs Kuhn

Field: Social Sciences (Social Sciences)

Click to increase image sizeClick to decrease image size Acknowledgements My thanks to Joan Leach for publishing the double issue of the journal that has prompted this long – and, also thanks to her, non‐libellous – response. It is dedicated to my partner, Stephanie Lawler, who has taught me the most about the importance of making decisions and taking responsibility for them. Additional informationNotes on contributorsSteve Fuller ** Correspondence to: Steve Fuller, Department of Sociology, University of Warwick, Coventry CV4 7AL, UK. Email: s.w.fuller@warwick.ac.uk. * Correspondence to: Steve Fuller, Department of Sociology, University of Warwick, Coventry CV4 7AL, UK. Email: s.w.fuller@warwick.ac.uk.
Formulation optimization and evaluation of Cefdinir nanosuspension using 23 Factorial design

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Poor water solubility and slow dissolution rate are the prime issues for the majority of upcoming and existing biologically active compounds. Cefdinir is a poorly water-soluble drug and its bioavailability is very low from its crystalline form. The purpose of the present investigation was to increase the solubility and dissolution rate of Cefdinir by preparation of its nanosuspension by solvent evaporation technique. The prepared formulation of nanosuspension was evaluated for its particle size, total drug content, entrapment efficiency, saturation solubility and in vitro dissolution. The optimized formulation was spray dried to obtain nanoparticles. The prepared nanoparticles were then evaluated for their particle size, saturation solubility and in-vitro drug release and the results were compared with the pure drug. A 23 factorial design was employed to study the effect of independent variables, amount of PVPK30 (X1), Poloxamer-188 (X2) and stirring rate (X3) on the dependent variables, particle size (nm,Y1) and in-vitro drug release (%, Y2). Validity of the developed mathematical equation was assayed by designing to check point. The results indicated the suitability of solvent evaporation method for Cefdinir with improved in vitro dissolution rate and thus perhaps enhance fast onset of action for the drug.
Ashrams and Kibbutzim

Field: Social Sciences (Social Sciences)

To try to compare Gandhi's various experiments in community living with Israel's kibbutzim at first sight appears to be a rash endeavour. But it is an endeavour which to my mind is fully justified. The wide umbrella of experiments in founding a new social order accommodates the histories of ideal (or even idealistic) communities in various parts of the globe. These quests for a Gemeinschaft felt to be missing in the extant social set-up range from those inspired by religious motives to those engendered by rationalist/radicalist/secularist thought. Different though these two poles may be, they yet share a common optimism about the feasibility of restructuring human institutions, for without such a faith the whole project of community building across kinship and other boundaries would be self-defeating. If the religiously inspired find warrant for moral perfectibility in divine sources, the radicals rely on the innate goodness of man when freed from the institutions which have led to his enslavement. This brings into focus another common element — the tendency to shun authority if not to challenge it. In this attempt to resist existing institutions, however, a new set of institutions with new foci of authority come into being. Pioneer religious communities have been particularly prone to this since they have nearly always developed around a 'guru' figure who provided an alternative focus of authority.KeywordsManual WorkCivil DisobedienceCommunity LivingCongress PartySimple LifeThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Defensive and Affective-Emotional Reactions to War: The Abkhazian War as Reflected in People's Subjective Reactions

Field: Psychology (Social Sciences)

Differences in defensive and affective-emotional reactions of 108 male Georgian subjects who had been confronted with the consequences of the Abkhazian war in different ways (nonwounded soldiers, wounded soldiers, and civilian controls) were significant between groups on all defense scales and four of the 12 Gottschalk-Gleser scales The results are discussed from a perspective with war forming for all three groups an important life event which differentially determined their psychological reactions.
Original Halley Method and its Improvement with Automatic Differentiation

Field: Mathematics (Physical Sciences)

Original Halley method, also referred to as the tangent hyperbolas method, is the classical third order method which can be used to solve the optimization problems. However, computing the derivative terms in solving the Halley equation becomes a key problem to reduce its computational cost. By using efficiently the techniques of automatic differentiation and preconditioned conjugate graduate method, original Halley method is established and improved in this paper. Theoretical and numerical results show that the improved version is more efficient than the original method.
A Novel Cell Density Prediction Design using Optimal Deep Learning with Salp Swarm Algorithm

Field: Computer Science (Physical Sciences)

Cell density prediction can be defined as the process of predicting the number of cells in a given quantity of a culture or cell suspension. It is considered a common practice in cell biology since cell density had a significant impact on cell behavior and can be utilized for monitoring the health and growth of cell culture. Precise prediction of cell density was significant for a range of applications in cell biology., which includes bioprocessing, cell-based assays, and cell culture. Therefore, this article develops a novel Cell Density Prediction design using Optimal Deep Learning with Salp Swarm Algorithm (CDP-ODLSSA) technique. The presented CDP-ODLSSA technique predicts the cell densities accurately on the images of cell suspensions or cultures. To do so, the presented CDP-ODLSSA technique employs Long Short Term Memory-Autoencoder (LSTM-AE) model for prediction of cell densities. In addition, the hyperparameter tuning of the LSTM-AE model takes place by the use of Salp Swarm Algorithm (SSA). For experimental validation of the CDP-ODLSSA technique, a wide range of simulations was taken place. The obtained values highlighted the superiority of the CDP-ODLSSA technique compared to other approaches.
Occupational Health Nurses' Experience in Occupational Health Nursing Practice Education

Field: Health Professions (Health Sciences)

본 연구는 산업간호실습을 지도한 산업간호사들의 특수한 경험을 탐색하여 현상을 깊이 있게 이해하기 위해 시도되었다. 참여자는 한 학기 이상 산업간호실습을 지도한 경험이 있는 8명의 산업간호사였다. 포커스 그룹으로 수집된 자료를 현상학적 방법으로 분석하였다. 분석 결과 산업간호사의 학생실습지도 경험은 4개의 범주, 13개의 주제모음, 27개의 주제로 도출되었다. 4개의 범주는 ‘자신의 경험에서 시작한 학생실습지도’, ‘어려움 속에서도 학생 실습을 진행함’, ‘보람을 느낌’, ‘대안의 제시’였다. 산업간호사의 학생실습지도에 있어서의 주요한 경험에 대한 이해 는 산업간호실습 교과목 특성에 맞는 실습규정의 수립 등 산업간호실습 교육과정을 개선 또는 개발하는데 참고자료 로 활용할 수 있을 것이다. 향후 산업간호실습을 경험한 간호대학생에 대한 질적 연구가 이루어진다면 산업간호실 습 교육과정 개선을 위한 좀 더 풍부한 자료를 제공할 수 있을 것이다.