jimnoneill/paper-to-field-training huggingface dataset:
Synthesis of N,N-dialkylaminosulfenylcarbamate insecticides via carbamoyl fluorides

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of N,N-dialkylaminosulfenylcarbamate insecticides via carbamoyl fluoridesCharles E. Hatch IIICite this: J. Org. Chem. 1978, 43, 20, 3953–3957Publication Date (Print):September 1, 1978Publication History Published online1 May 2002Published inissue 1 September 1978https://doi.org/10.1021/jo00414a033Request reuse permissionsArticle Views267Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (652 KB) Get e-Alertsclose Get e-Alerts
SMART CARD TRANSIT SYSTEMS AND THE POTENTIAL FOR SYNERGISTIC PARTNERING WITH PUBLIC AND PRIVATE SECTOR CARD DEPLOYMENTS

Field: Engineering (Physical Sciences)

There are numerous organizations planning to deploy large multi-agency or regional smart card systems for both payment and non-payment applications. Smart cards are being targeted for their robust technical capabilities that support complex program needs and multiple applications on a single card. The purpose of this paper is to explore the potential for transit agencies to partner with non-transit entities in deploying joint smart card systems. Potential benefits of partnering include cost sharing, improved customer access and service, as well as other synergistic benefits.
Evaluating the effectiveness of adaptive antenna array in weight coefficients discretization

Field: Engineering (Physical Sciences)

Currently, there is a shortage of using radio resources in the world and there is an acute need for using additional physical resources that increase the bandwidth of communication channels and increase the productivity of mobile communication systems in general. The use of space-time physical parameters in the organization of multiple access (STA) of subscribers is becoming relevant. \n\nThe methods of subscriber stations (SSs) STA to the resources of the base station (BS) are based on the use of -element adaptive antenna arrays (AAA). The methods and algorithms of AAA synthesis are based on the evaluation of the complex vector of weight coefficients (VWC) included in the reception paths of each antenna element (AE) and controlled by various algorithms. Therefore, the object of research is the process of discretization of the weight coefficients in the adaptive antenna array.\n\nThe main disadvantage identified during the audit in this study is the calculation of the computational complexity of the quantization algorithm for weight coefficients for different variations in the parameters of the signal-interference situation at the AAA input.\n\nComplex, systemic evaluation of the effectiveness of AAA functioning taking into account the chosen criterion of the effectiveness of the AAA operation, using the procedure for quantizing the weight coefficients, is possible with a broader and precise specification of the parameters of the operating signal-interference environment. This will allow to obtain reliable results.\n\nThe required dimensionality of the adaptive array antenna weights is determined depending on the ratio of the total interference power to the internal noise power at the input of the bandpass filter, based on the allowable decrease in the average output signal-to-interference-plus-noise ratio.\n\nOn the basis of the obtained analytical estimation of the loss rate, an expression for calculating the required quantizer capacity is proposed. It is possible to show that, regardless of the amount of allowable losses, the required quantizer capacity is increased by 1 bit with an increase in the input interference/noise ratio by 6 dB.
A T-helper/suppressor ratio in renal allograft recipients after various long-term immunosuppressive regimens.

Field: Medicine (Health Sciences)

The response of T-helper and T-suppressor cells to various immunosuppressive regimens was studied in long surviving cadaveric renal allograft recipients. Eight patients were immunosuppressed with Azathioprine and corticosteroids, 12 recipients were treated with a combination of Cyclosporin A, corticosteroids and Azathioprine for 1 year. Both regimens decreased the Th/Ts ratio significantly as compared with healthy controls (p less than 0.05). No correlation between the Th/Ts ratio and the serum creatinine concentration was found. Likewise, the Th/Ts ratio did not correlate with Cyclosporin A blood levels.
Conclusion on the peer review of the pesticide risk assessment of the active substance Fatty acids C7 to C18 (approved under Regulation (EC) No 1107/2009 as Fatty acids C7 to C20)

Field: Agricultural and Biological Sciences (Life Sciences)

The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State Ireland, for the pesticide active substance fatty acids C7 to C18 are reported. The context of the peer review was that required by Commission Regulation (EC) No 2229/2004 as amended by Commission Regulation (EC) No 1095/2007. The conclusions were reached on the basis of the evaluation of the representative uses of fatty acids C7 to C18 as a herbicide, acaricide, insecticide or plant growth regulator on a variety of crops. The reliable endpoints concluded as being appropriate for use in regulatory risk assessment, derived from the available studies and literature in the dossier peer reviewed, are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are identified.
Supplementary Tables3-5,7-9 from Expression Levels of Therapeutic Targets as Indicators of Sensitivity to Targeted Therapeutics

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

<p>Supplementary Table 3a: Molecular Targets of the Anticancer Drugs from GDSC, CTRP and DrugBank. Spearman correlation and permutation testing results are provided for both the GDSC and CTRP datasets. Supplementary Table 4: List of drugs where we observe both a correlated and an anti-correlated target in GDSC and CRTP datasets. Supplementary Table 5: Fractions of single cells in each cell line expressing both targets from Figure 3. Supplementary Table 7: Transcript isoform aware reanalysis of CTRP-GDSC concordance. Spearman correlation values between drug sensitivity and drug-target transcript isoforms expression for 74 drugs common between GDSC and CTRP. The 541 cell lines common in GDSC and CTRP where drug-target transcript isoform expression and AUC values could be obtained were considered. As GDSC and CTRP provide gene-level expression measurements from different microarray versions (Affymetrix GeneChip HG-U133A in GDSC and HG-U133PLUS2 in CTRP), which potentially detect different isoforms of each gene, we repeated our analysis at the transcript level. Supplementary Table 8: The top 20 strongest correlations and top 20 strongest anti-correlations between drug sensitivity and gene expression for the GDSC and CTRP datasets. Supplementary Table 9: Drug-target pairs that are significantly correlated in cell lines derived from a cancer subtype but not significantly correlated in the pan-cancer analysis.</p>
SH532909.07FU

Field: Agricultural and Biological Sciences (Life Sciences)

UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
[Aberrant methylation of tumor suppressor genes in renal cell carcinoma].

Field: Medicine (Health Sciences)

Promoter CpG methylation is a major epigenetic mechanism to inactivate the functions of tumor suppressor genes (TSG), in addition to genetic mechanism (point mutation and deletion), plays important roles in the pathogenesis of various tumors. Renal cell carcinoma (RCC) is a malignant tumor with poor prognosis, in which aberrant methylation of TSGs has also been widely reported. Most RCC patients are presented with advanced disease because early stage RCC does not have apparent symptoms. The detection of TSG methylation might provide new specific biomarkers for early non-invasive diagnosis of this disease. Because RCC is generally insensitive to conventional chemotherapy and radiotherapy, using epigenetic agents, such as azacytidine, to modulate the activities of DNA methyltransferases and reverse the methylation status of TSGs might be an attractive strategy for future treatment of RCC, which could be combined with conventional therapies. We reviewed recent advances in the research on TSG methylation in RCC, summarized the methylation profile of RCC-related genes, including HOXB13, HAI2/SPINT2, CDH1 and CTNNG/JUP, and discussed the clinical significance of aberrant CpG methylation for the diagnosis and treatment of RCC.
Cellular side of acquired immunity (T cells)

Field: Immunology and Microbiology (Life Sciences)

The adaptive T-cell response represents the most sophisticated component of the immune response. Foreign invaders are recognized first by cells of the innate immune system. This leads to a rapid and non-specific inflammatory response, followed by induction of the adaptive and specific immune response. Different adaptive responses can be promoted, depending on the predominant effector cells that are involved, which themselves depend on the microbial/antigen stimuli. As examples, Th1 cells contribute to cell-mediated immunity against intracellular pathogens, Th2 cells protect against parasites, and Th17 cells act against extracellular bacteria and fungi that are not cleared by Th1 and Th2 cells. Among the new subsets, Th22 cells protect against disruption of epithelial layers secondary to invading pathogens. Finally these effector subsets are regulated by regulatory T cells. These T helper subsets counteract each other to maintain the homeostasis of the immune system, but this balance can be easily disrupted, leading to chronic inflammation or autoimmune diseases. The challenge is to detect early changes in this balance, prior to its clinical expression. New molecular tools such as microarrays could be used to determine the predominant profile of the immune effector cells involved in a disease process. Such understanding should provide better therapeutic tools to counteract deregulated effector cells.
Long-term anticoagulant therapy in the aspect of secondary prevention of recurrent pulmonary embolism

Field: Medicine (Health Sciences)

Aim. To determine differences in laboratory coagulation parameters using routine and integral monitoring methods in patients depending on anticoagulant therapy >12 months after pulmonary embolism (PE) with a high recurrence risk. Material and methods. The study included 72 patients who, according to indications, received long-term anticoagulant therapy >12 months due to a high risk of recurrent thromboembolism. During the follow-up period (15-20 months from the first pulmonary embolism episode), the plasma coagulation parameters were studied using a conventional panel and D-dimer assessment, as well as a thrombin generation test and thrombodynamics. Patients adherent to prolonged anticoagulation were included in group 1. During the collection period, 8 patients independently stopped taking anticoagulants, despite the high risk of recurrent pulmonary embolism (group 2). Results. There were no significant differences in coagulation parameters and D-dimer levels between the studied groups of patients. In the group of patients continuing to take anticoagulants, there was an increase in clot growth delay parameters in comparison with patients of group 2 according to the thrombodynamics results (p=0,046) and the thrombin generation test in platelet-poor plasma in comparison with reference values (p=0,001). Conclusion. Long-term anticoagulant therapy effectively prevents recurrent venous thromboembolism. In patients after primary pulmonary embolism who refuse anticoagulation, the clot growth delay values are shortened, which indicates an increased risk of recurrent venous thromboembolism. The most stable plasma coagulation parameters are observed in patients taking direct oral anticoagulants.
Predatory Potential of Chrysoperla zastrowi sillemi (Esben-Peterson) and Cryptolaemus Predatory Potential of Chrysoperla zastrowi sillemi (Esben-Peterson) and Cryptolaemus Montrouzieri Mulsant on Paracoccus marginatus (Williams and Gr

Field: Agricultural and Biological Sciences (Life Sciences)

Predatory potential of Chrysoperla zastrowi sillemi (Esben-Peterson) and Cryptolaemus montrouzieri Mulsant on Paracoccus marginatus (Williamsand Granara de Willink) infesting sunflower was studied in the lab. Results revealed that grubs of C. zastrowi sillemi was 1.4 ± 0.5, 85.0 ± 7.3 and 13.2 ± 1.3 ovisacs, nymphs and adults, respectively. Among various instars of the predator, second and third instar were voracious and consumed 1.6 ± 0.5, 139.0 ± 5.4 and 22.8 ± 2.1 and 3.4 ± 0.5, 230.4 ± 29.2 and 32.5 ± 2.6 ovisacs, nymphs and adults of P. marginatus, respectively. Grubs of C. montrouzieri fed 7.6 ± 0.7, 153.6 ± 23.8 and 62.8 ± 11.6 ovisacs, nymphs and adults of P. marginatus to complete their life stages. Among various instars of the predator, third and fourth instar were voracious and consumed 2.2 ± 0.4, 43.6 ± 2.0 and 23.2 ± 3.0 and 2.8 ± 0.4, 69.6 ± 4.6 and 27.6 ± 4.6 ovisacs, nymphs and adults of P. marginatus, respectively. Adult C. montrouzieri consumed on an average 5.2 ± 0.8, 101.2 ± 13.5 and 35.4 ± 8.6 ovisacs, nymphs and adults of P. marginatus .
Regulatory noncoding RNAs at Hox lociThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

There is growing awareness of the importance of noncoding (nc)RNAs in the regulation of gene expression during pattern formation in development. Spatial regulation of Hox gene expression in development controls positional identity along the antero–posterior axis. In this review, we will focus on the role of short ncRNAs that repress Hox genes in Drosophila and mammals by RNA interference (RNAi), on long ncRNAs that may repress a Hox in cis in Drosophila by transcriptional interference, and on a novel long ncRNA that functions in trans to regulate Hox genes mammals.
The ‘Dublin Penny journal’

Field: Arts and Humanities (Social Sciences)

The ‘Dublin Penny journal’ Get access W. H. Patterson W. H. Patterson 1Belfast Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume s7-II, Issue 45, 6 November 1886, Page 375, https://doi.org/10.1093/nq/s7-II.45.375b Published: 06 November 1886
LightScan: Faster Scan Primitive on CUDA Compatible Manycore Processors

Field: Computer Science (Physical Sciences)

Scan (or prefix sum) is a fundamental and widely used primitive in parallel computing. In this paper, we present LightScan, a faster parallel scan primitive for CUDA-enabled GPUs, which investigates a hybrid model combining intra-block computation and inter-block communication to perform a scan. Our algorithm employs warp shuffle functions to implement fast intra-block computation and takes advantage of globally coherent L2 cache and the associated parallel thread execution (PTX) assembly instructions to realize lightweight inter-block communication. Performance evaluation using a single Tesla K40c GPU shows that LightScan outperforms existing GPU algorithms and implementations, and yields a speedup of up to 2.1, 2.4, 1.5 and 1.2 over the leading CUDPP, Thrust, ModernGPU and CUB implementations running on the same GPU, respectively. Furthermore, LightScan runs up to 8.9 and 257.3 times faster than Intel TBB running on 16 CPU cores and an Intel Xeon Phi 5110P coprocessor, respectively. Source code of LightScan is available at http://cupbb.sourceforge.net.
Collaboration, Discussion, and Feedback for Improving Students’ (Report) Writing and Presentation: A Participatory Action Research

Field: Social Sciences (Social Sciences)

This study investigates how model presentation, collaboration, discussion, and peer feedback as the intervention of participatory action research (PAR) improved students' academic writing (AW) and presentation skills while dealing with a practical course ‘ELT seminar and report writing’. We implemented the intervention for three months in our regular class with 30 students pursuing a Master's Degree in English Education from Tribhuvan University, Nepal. During the intervention, we used observation notes and after the intervention, we used semi-structured interviews (with 15 students) to collect data. The findings showed that the intervention significantly improved the students' AW and presentation skills. The findings also showed that students refined their writing skills by gaining insight from the model presentation, discussions, and feedback. They significantly improved their writing and presentation skills through collaborative tasks performed regularly during the study. The study suggests that model presentation, group discussion, peer and teacher feedback, and self-reflection can be effective in enhancing students' AW and presentation.
Saikosaponin-A induces apoptosis of cervical cancer through mitochondria- and endoplasmic reticulum stress-dependent pathway in vitro and in vivo : involvement of PI3K/AKT signaling pathway

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Cervical cancer causes considerable mortality in women worldwide. Saikosaponin-A, a triterpenoid glycoside isolated from Bupleurum falcatum, has been proven to exert anti-cancer property. In this study, we evaluated the possibility of saikosaponin-A on cervical cancer in vitro and in vivo. The results showed that saikosaponin-A induced cell death and altered cellular morphology dose-dependently. Saikosaponin-A significantly induced apoptosis in HeLa cells, confirmed by Hoechst 33,342 staining and flow cytometry. Sequentially, saikosaponin-A triggered the mitochondrial-mediated apoptosis demonstrated by deficiency of MMP, induction of Bax/Bcl-2 ratio, leakage of cytochrome c to cytoplasm, and activation of caspase-3. Moreover, ER stress also participated in the apoptosis induced by saikosaponin-A in HeLa cells as indicated by the upregulation of GPR78, CHOP and caspase-12 expression. Furthermore, HeLa cells showed increased expressions of p-PI3K and p-AKT in response to saikosaponin-A treatment. Additionally, saikosaponin-A could inhibit HeLa tumor growth in nude mice and induce apoptosis, reflected by the induction of TUNEL and the expression of cytochrome c, caspase-3 and CHOP confirmed by immunohistochemistry. These findings at least to a certain extent suggested that saikosaponin-A triggered apoptosis through both mitochondrial pathway and ER stress pathway and inhibiting PI3K/Akt signaling, thereby contributing to against cervical cancer. This work provides a new understanding of saikosaponin-A on therapeutic application in treatment of cancer, which has the potential to be a promising candidate therapeutic agent for cervical cancer patients.
[Pharyngitis produced by Arcanobacterium haemolyticum].

Field: Medicine (Health Sciences)

Arcanobacterium haemolyticum (A.h.) was recovered from 0.43% of throat cultures of 3715 patients with sore throat, scarlatina and various skin rash. In a 57.90% patients A.h. was the only bacterial pathogen isolated, while in the remainder beta-haemolytic streptococci, Haemophilus and S. aureus were also detected. beta-haemolytic streptococci were much more frequent than A.h. in the throat cultures (26.83%). All A.h. strains were of the smooth type based on colony morphology and the ability to ferment sucrose. The strains were susceptible to penicillins, cephalosporins, erytromycin and resistant to trimethoprim-sulphamethoxazole. Pharyngeal injection in 89.47% and exanthem in 78.90% were the most common signs present to the patients.
Llyfr Mormon: The Translation of the Book of Mormon into Welsh

Field: Arts and Humanities (Social Sciences)

Research Article| April 01 2002 Llyfr Mormon: The Translation of the Book of Mormon into Welsh Ronald D. Dennis Ronald D. Dennis Ronald D. Dennis, a professor of Portuguese at BYU, is also an authority on the history of the Church of Jesus Christ of Latter-day Saints in Wales. His recent focus in that area has been on producing facsimile translations of 70 Welsh missionary publications from the 1840s and 1850s. Search for other works by this author on: This Site Google Journal of Book of Mormon Studies (1992-2007) (2002) 11 (1): 45–49. https://doi.org/10.5406/jbookmormstud.11.1.0045 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation Ronald D. Dennis; Llyfr Mormon: The Translation of the Book of Mormon into Welsh. Journal of Book of Mormon Studies (1992-2007) 1 April 2002; 11 (1): 45–49. doi: https://doi.org/10.5406/jbookmormstud.11.1.0045 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All Scholarly Publishing CollectiveUniversity of Illinois PressJournal of Book of Mormon Studies Search Advanced Search The text of this article is only available as a PDF. Copyright 2002 by the Board of Trustees of the University of Illinois2002 Article PDF first page preview Close Modal Issue Section: The Sesquicentennial of Four European Translations of the Book of Mormon You do not currently have access to this content.