jimnoneill/paper-to-field-training huggingface dataset:
Closer than a brother? Assessing Singapore-Israel relations

Field: Social Sciences (Social Sciences)

Singapore's close relationship with the Jewish State has been a consistent source of controversy - domestic, regional and international - since its inception in the late I 950s. Critics claim that Singapore's close ties with Israel jeopardise its safety and morality. The relationship is unusual in many respects, and brings with it numerous risks - security and otherwise- that Singapore could well do without. In spite of this, it has since blossomed, and in many ways, both have become to each other the proverbial friend that sticketh closer than a brother. This study attempts to i) summarise the criticisms of the Singapore-Israel relationship, ii) provide a brief historical context of the ties, iii) examine its unrivalled controversy, iv) consider whether Singapore ought therefore to cool the relationship, v) anticipate the concomitant threats to Singapore if it does not, and vi) suggest what Singapore can do to mitigate likely threats. Its central thesis is that cooling Singapore-Israel relations will make Singapore no safer nor moral despite the obvious difficulties the relationship entails. It examines calls for Singapore to 'take a stronger position against Israel' and cautiously suggests that there still appear to be reasonable grounds for Singapore and Israel to maintain the excellent state of relations they have shared since establishing contact.
Just transition and welfare states: a largely unexplored relation

Field: Social Sciences (Social Sciences)

Climate emergency has been recognised as a top policy priority by more and more policy-makers and the restructuring process it entails is seen as the main challenge of the coming decades. The welfare state that emerged in the context of a fossil fuel-based extractive economic model, based on a belief in sustained growth, cannot remain unaffected by the ongoing transition to a net-zero economy (Gough et al., 2008). Possible linkages between the welfare state and climate and environmental issues largely remain unexplored and until very recently discussion of social welfare systems in Europe has been disconnected from ecological concerns and policies and as well from the just transition narrative that took a prominent role in shaping the social dimension of climate policies. Both on the other hand assume continuing economic growth. This article aims to present a broad mapping of the current debates mainly at EU level, highlighting possible alternative directions (from green growth to sustainable welfare; from technology to behavioural changes). It proceeds through selected literature reviews offering a dialogue between different perspectives and opening successive routes of questioning. It also highlights the current limitations in the analysis of the role and the shape of welfare states in tackling environmental challenges and labour market transitions.
Mapping of Apoptin-interaction with BCR-ABL1, and development of apoptin-based targeted therapy

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Majority of chronic myeloid leukemia patients experience an adequate therapeutic effect from imatinib however, 26-37% of patients discontinue imatinib therapy due to a suboptimal response or intolerance. Here we investigated derivatives of apoptin, a chicken anemia viral protein with selective toxicity towards cancer cells, which can be directed towards inhibiting multiple hyperactive kinases including BCR-ABL1. Our earlier studies revealed that a proline-rich segment of apoptin interacts with the SH3 domain of fusion protein BCR-ABL1 (p210) and acts as a negative regulator of BCR-ABL1 kinase and its downstream targets. In this study we show for the first time, the therapeutic potential of apoptin-derived decapeptide for the treatment of CML by establishing the minimal region of apoptin interaction domain with BCR-ABL1. We further show that the apoptin decapeptide is able to inhibit BCR-ABL1 down stream target c-Myc with a comparable efficacy to full-length apoptin and Imatinib. The synthetic apoptin is able to inhibit cell proliferation in murine (32Dp210), human cell line (K562), and ex vivo in both imatinib-resistant and imatinib sensitive CML patient samples. The apoptin based single or combination therapy may be an additional option in CML treatment and eventually be feasible as curative therapy.
Surgical management of skin infection with mycobacterium fortuitum:a report of 59 cases

Field: Medicine (Health Sciences)

Objective To determine the optimal time,indication and type of surgical management for the skin infection with mycobcterium fortuitum. Methods The treatment effects of different surgical management for this disorder were retrospectively compared and analyzed. Results Fifty two focal lesions(FLs) were surgically removed in 45 cases. Phase I healing was obtained in all FLs except recurrence in 8 FLs. Incision and draining or curettage were performed in 6 cases, of which 5 were cured,and the other new focal lesion formation was found and cured by secondary currettage.AMK was locally applied in 8 cases after extraction of abscess without removal of the lesion,and all the 8 cases were cured.All the 59 cases were cured after combination treatment. Conclusions The optimal time for local surgical treatment of skin Mf infection is when the focal lesion has been well controlled and granulation formed after 6～8 weeks of systemic treatment.The removal of focal lesion should be done,the resection margin of the skin should be 1.5～2cm far away the lesion.
SIGNIFICANCE OF VARIABLES AFFECTING PROFITABILITY OF AIRLINE

Field: Business, Management and Accounting (Social Sciences)

Global event such as war, pandemic, political embargos affect overall economy of airline carrier by influencing the most important variables such as load factor or fuel prices Aim of all companies is to be profitable, what means to cover all constant costs and fuel costs with profit from tickets which are closely linked with load factor In this study we chose to study economic impact of COVID-19 pandemic and its effect on load factor and fuel prices and overall economy To describe the problem, we chose yearly economy of fictive airline carrier that flies two Airbus A319 aircrafts on three routes flying from Bratislava - BTS to Riyad - RUH, Jeddah - JED and Kuwait - KWI Data used for exemplary calculations are based on real resources during usual year and year affected by COVID-19 To describe the issue of fuel global events influencing fuel price and load factor fictive airline provider Constant costs will be summarized and variables - load factor, ticket price a fuel price will be calculated based on realistic indicators As first, realistic fuel price will be used and compared to different price amounts over last year Realistic price will be taken from one year ago, because recent pandemic of Covid1-19 virus caused 60%-80% drop in fuel price since last year This will be only showcase of uncontrolled global events affection on fuel prices, used with real data calculations as a result Load factor and ticket prices are important variables, where it is simple to change ticket price from the side of company and in this showcase, we will study the effect of COVID-19 pandemic effect on final economy of this company As first, we will study fuel price evolution during COVID-19 pandemic, then we will study load effect of pandemic on load factor from realistic values from the time of its eruption and following official predictions we will calculate yearly economy results throughout the year of 2020 In conclusion, we can state that despite the bad impact of the global pandemic covid-19 on the world economy, the impact of this pandemic on nature is exactly the opposite In the world, we can notice a trend of renewal and improvement of environmental activities © 2020 International Multidisciplinary Scientific Geoconference All rights reserved
ELECTRIC SHOCK THERAPY IN THE TREATMENT OF SCHIZOPHRENIA, MANIC DEPRESSIVE PSYCHOSES AND CHRONIC ALCOHOLISM

Field: Medicine (Health Sciences)

Neymann, Clarence A. A.B., M.D.; Urse, V. G. B.S., M.D.; Madden, John J. B.S., M.D.; Countryman, M. Alden B.S., M.S., Ph.D. Author Information
Radio Electrons and Magnetic Fields in the Galactic Halo

Field: Physics and Astronomy (Physical Sciences)

view Abstract Citations (19) References (35) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Radio Electrons and Magnetic Fields in the Galactic Halo Felten, James E. Abstract The density of radiating electrons in the galactic halo is re-examined in the light of recent cosmic-ray data. A flux 4)h(E) 0 8 X 10-2 2 4 (cm2 sec ster GeV)-1 in 0 63.5 GeV is proposed; this is 1-2 per cent of the quiescent primary proton flux and is higher than estimates used previously in deriving the halo magnetic field from radio brightness measurements and models of the halo. The halo field implied by such a flux is (2-3.5) X 10 gauss; the lower figure corresponds to the uniform radio emissivity originally given for the halo by Baldwin, the higher to Mills's value for the central regions. Higher field estimates obtained analogously by other authors are discussed. Publication: The Astrophysical Journal Pub Date: August 1966 DOI: 10.1086/148798 Bibcode: 1966ApJ...145..589F full text sources ADS |
Research Hotspots in Psoriasis: A Bibliometric Study of the Top 100 Most Cited Articles

Field: Medicine (Health Sciences)

(1) Introduction: Psoriasis is a chronic, immune-mediated disease that negatively impacts patients’ quality of life and predisposes them to cardiovascular or metabolic diseases. This paper aims to summarize the knowledge structure and future directions in psoriasis research by means of bibliometrics. (2) Material and methods: The Thomson Reuters Web of Science database was interrogated using preestablished keywords. A list of the top 100 most cited articles focusing solely on psoriasis was compiled and analyzed. VOSviewer software was used to assess and visualize collaboration networks, citation, co-citation and co-wording analysis, and bibliographic coupling. (3) Results: The articles were written by 902 authors from 20 countries and were published in 31 journals. The United States was at the forefront of this field. Griffiths, CEM had the most citations, while the most prolific institution was Rockefeller University, New York City. Pathogenesis, especially key-pathogenic factors, immune pathways, and epidemiology were the most discussed topics. Work published in the last decade focused on the use of biologics. Keywords such as “quality of life”, “efficacy”, and “necrosis-factor alpha” have been widely used. (4) Conclusion: Research interest regarding psoriasis is high, leading to the rapid development of this field. Treatment modalities, especially novel-targeted therapies, immune pathways, and an integrative approach to such cases are receiving great interest and represent research hotspots in the future.
When cues collide: use of stress and statistical cues to word boundaries by 7- to 9-month-old infants.

Field: Psychology (Social Sciences)

Prior research suggests that stress cues are particularly important for English-hearing infants' detection of word boundaries. It is unclear, though, how infants learn to attend to stress as a cue to word segmentation. This series of experiments was designed to explore infants' attention to conflicting cues at different ages. Experiment 1 replicated previous findings: When stress and statistical cues indicated different word boundaries, 9-month-old infants used syllable stress as a cue to segmentation while ignoring statistical cues. However, in Experiment 2, 7-month-old infants attended more to statistical cues than to stress cues. These results raise the possibility that infants use their statistical learning abilities to locate words in speech and use those words to discover the regular pattern of stress cues in English. Infants at different ages may deploy different segmentation strategies as a function of their current linguistic experience.
Functional Expression of SAV3818, a Putative TetR-Family Transcriptional Regulatory Gene from Streptomyces avermitilis, Stimulates Antibiotic Production in Streptomyces Species

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Avermectin and its analogs are major commercial antiparasitic agents in the fields of animal health, agriculture, and human infections. Previously, comparative transcriptome analysis between the low-producer S. avermitilis ATCC31267 and the high-producer S. avermitilis ATCC31780 using a S. avermitilis whole genome chip revealed that 50 genes were overexpressed at least two-fold higher in S. avermitilis ATCC31780. To verify the biological significance of some of the transcriptomics-guided targets, five putative regulatory genes were individually cloned under the strong-andconstitutive promoter of the Streptomyces expression vector pSE34, followed by the transformation into the lowproducer S. avermitilis ATCC31267. Among the putative genes tested, three regulatory genes including SAV213, SAV3818, and SAV4023 exhibited stimulatory effects on avermectin production in S. avermitilis ATCC31267. Moreover, overexpression of SAV3818 also stimulated actinorhodin production in both S. coelicolor M145 and S. lividans TK21, implying that the SAV3818, a putative TetR-family transcriptional regulator, could be a global upregulator acting in antibiotic production in Streptomyces species.
Hypertrophic pulmonary osteoarthropathy associated with disease progression in renal cell carcinoma.

Field: Medicine (Health Sciences)

Hypertrophic osteoarthropathy (HOA) is a paraneoplastic syndrome characterized by periosteal formation and arthritis and usually accompanied by clubbing ofthe digits. Many malignancies have been associated with HOA/clubbing, most being lung cancer and lung metastatic cancer. We herein present a 53-year-old man with lung metastasis from renal cell carcinoma (RCC). HOA occurred one year after the metastasis. Reviewing the literature, only five cases of RCC with HOA have been reported. If their clinical history was traceable, they consistently had disease progression. We reviewed the pathogenesis of HOA/clubbing and linked the prognosis of RCC to relevant cytokines. Therefore, HOA not only heralds a progression of disease but suggests a probable therapeutic choice by targeting some cytokines.
SUN-599 A Case Of Synchronous Follicular, Medullary, And Follicular Variant Of Papillary Carcinoma In A Single Thyroid Gland: A Lesson In Integrating Management

Field: Medicine (Health Sciences)

Background: The presence of multiple distinct types of thyroid cancer within the same thyroid gland has been described but is rare. Medullary thyroid carcinoma is managed differently from other forms of differentiated thyroid cancer when presenting solely. Clinical Case: A 59 year old woman presented to her primary care provider complaining of a neck lump. A thyroid ultrasound revealed a 3.4 cm right thyroid lobe nodule. FNA was performed and suspicious for a follicular neoplasm. A right hemithyroidectomy and isthmusectomy revealed a 3.0 cm at least minimally invasive follicular carcinoma with involved margins with pathologic diagnosis limited by the anterior surface of the thyroid having been disrupted during surgery. There also was an incidental 1.5 mm medullary carcinoma noted. A left completion thyroidectomy then found a 1 mm follicular variant of papillary carcinoma. She was referred for further subspecialty Endocrinology and ENT care for her stage II or higher follicular cancer along with medullary and follicular variant of papillary microcarcinomas. Laboratory evaluation included a TSH of 10.800 (0.360-3.740 mIU/L), thyroglobulin 7.0 (1.5-38.5 ng/mL), thyroglobulin antibody < 1.0 (0.0-0.9 IU/mL), calcitonin < 2.0 (0.0-5.0 pg/mL), CEA 1.3 (< 3.0 ng/mL), calcium 8.8 (8.5-10.1 mg/dL), PTH 36 (14-64 pg/mL), vitamin D 30 (30-100 ng/mL), plasma normetanephrines 38 (0-145 pg/ml), plasma metanephrines 10 (0-62 pg/mL), and RET mutation negative. Her postsurgical hypothyroidism was treated with levothyroxine doses titrated to goal TSH < 0.1. Contrasted neck CT revealed postsurgical changes with no concerning adenopathy. These findings led to a decision against reoperation to include neck dissection but delayed radioactive iodine treatment. Approximately 2.5 months after her iodinated contrast exposure, she was treated with 100 mCi of radioactive iodine 131 via Thyrogen stimulation. Posttreatment whole body scan showed uptake at the thyroid bed but was negative for metastatic disease. Subsequent calcitonin was < 2.0 and CEA 0.7 with ultrasound only showing a 0.4 mm hypoechoic nodule versus node in the right thyroid fossa. One year after her completion thyroidectomy and six months after ablation, TSH was 0.019, thyroglobulin 0.1, thyroglobulin antibody < 1.0, calcitonin < 2 (≤ 5 pg/mL), CEA 0.8, and ultrasound was free of any concerning lesions. She remained on suppressive levothyroxine and further surveillance performed via Thyrogen stimulation with thyroglobulin < 0.1, thyroglobulin antibody < 1.0, and radioactive iodine whole body scan negative for evidence of disease. Clinical Lesson: Coincident follicular thyroid cancer with medullary and follicular variant of papillary thyroid cancer is rare but each malignancy can be managed concurrently yet independently of the other as per current practice standards.
Alleviation of Soil Compaction Effect by using Rice Straw under Different Moisture Contents

Field: Agricultural and Biological Sciences (Life Sciences)

Soil compaction considered a problem that affects several soil properties and plant growth parameters.In order to assess the effects of soil compaction (expressed as bulk density) under different levels of moisture content and rice straw on some soil properties, plant growth parameters and macro nutrients uptake by sorghum plant (Sorghum bicolor (L.) Moench, Dorado sp.)To achieve this purpose, a columns experiment was conducted at the farm of Faculty of Agriculture, Al-Azhar University, Nasr City, Cairo, Egypt during the summer season of 2017.Plastic columns (Cylindrical PVC pots) of 15 cm inside diameter and 45 cm depth were used.The treatments of experiment consisted of three soil compactions leading to the following bulk densities: 1.35; 1.50 and 1.65 Mg m -3 , two moisture content 75 and 100% of field capacity (FC), and three rates of rice straw(RS) < 2 mm were application to soil :0.0,0.5 and 1%.The results obtained that there is a great potential in managing the soil by the addition of rice acompaction for the development and growth of sorghum plant.Generally, pH decreased with increasing soil compaction under the studied levels of moisture content and rice straw.But EC values increased significantly with increasing bulk density as indicator as soil compaction.Rice straw improving soil EC values at 100% FC as a result of decreasing bulk density.Increasing rice straw in soil has the potential to improve soil hydraulic properties.Length, fresh and dry weights of shoot and root are influenced by bulk density and rice straw as well as moisture availability.At the lowest soil compaction (1.35 Mg m -3 ), all parameters of sorghum plant increased with increasing moisture content.While, the highest level of moisture content (100% FC) gave the opposite effect at the others levels of bulk density (1.5 and 1.65 Mg m -3 ).Generally, the favorable condition for plant growth has request low bulk density, and good hydraulic conductivity.Also, the concentration of N, P and K decreased significantly with increasing soil compaction.It can be noticed that N content increased significantly with increasing rice straw (RS) at 75% moisture content of field capacity, then decreased at 100% at the highest levels of soil compaction (1.65 Mg m -3 ).P and K content increased with increasing rice straw and moisture content as a result of decreasing soil compaction.Also, uptake of N, P and K increased significantly with increasing rice straw and moisture content especially, at the low level of soil compaction.
Panama leak to boost global fight against tax evasion

Field: Economics, Econometrics and Finance (Social Sciences)

Significance The 'Panama papers' disclosures brought attention to the weak harmonisation of corporate tax policies, creating loopholes that can be exploited to avoid and evade tax. The resulting pressure for tighter regulation puts the future of offshore centres at risk in the long term. Impacts Companies and banks will need to review staffing and data-management capability to take on a new self-regulatory role. Technology investment will rise, as the private sector gets to grip with increasing data-management requirements. The functions of due diligence, compliance and internal audit will expand rapidly.
The Use of Social Media for Recruitment and Selection: Exploring HR Professionals’ Perceptions of Utility, Ethicality, and Risk

Field: Business, Management and Accounting (Social Sciences)

Human resource (HR) professionals’ use of social media for recruitment and selection has steadily risen in recent years, and this trend is predicted to continue. As usage has become more prolific, so too have concerns involving the utility, ethicality, and risk of using social media for HR-related purposes. This cross-sectional quantitative study examined HR professionals’ perceptions of the use of social media for recruitment and selection. Specifically, it assessed the relationships between (1) perceived utility and perceived ethicality, and (2) perceived utility and perceived risk. In addition, the relationships between demographic factors and perceived utility, perceived ethicality, and perceived risk were studied. Those demographic factors included gender, education level, and organization size. Data were collected from members of local Society for Human Resource Management (SHRM) chapters. This research also discusses implications for the human resources field and recommendations for future research.
SYSTEMATIC REVIEW OF GOOGLE CLASSROOM USE AS AN EDUCATION PLATFORM AT HIGHER EDUCATION ELT CONTEXT IN INDONESIA

Field: Arts and Humanities (Social Sciences)

Google Classroom is an education-based platform to support learning activities with free access. Google Classroom has various features that make it easier for students and teachers to conduct online learning and teaching activities. This study aims to analyze the use of Google Classroom in ELT in Indonesia and find the strength and weaknesses of using Google Classroom. The method used in this study is a systematic literature review. The instrument in this research is document analysis and the object of this research is ten research papers that are systematically collected based on predetermined criteria namely, a research paper that concerns Google Classroom usage in Indonesian ELT at the Higher Education level, a research paper in the last five years, and indexed by Sinta 1 to 4. The results of this research analysis show that various activities for ELT learning can be implemented through Google Classroom. The activities include listening to the audio, speaking practice through video, reading and writing text, communicating, discussing, giving an exam, collecting assignments, also providing, explaining, and sharing the material. In addition, the advantages that Google Classroom has based on the literature studied are that it is efficient, able to record task, effective, quick access, easy storage of materials, flexible, understanding of character and technology, score transparent, paperless, autonomous learning, and cost-effective. While for the weaknesses, the studies indicate that Google Classroom has limited communication and discussion, screen display and internet connection trouble, limited feedback, also it takes time to master all the features of Google Classroom requires an internet connection to be able to access the features. In the future, the researchers are able to conduct a study about Google Classroom in a comprehensive, therefore the result more detailed and explicit.