Cholangiocarcinoma and AIDS-Related Sclerosing Cholangitis

Field: Medicine (Health Sciences)

Letters20 June 2000Cholangiocarcinoma and AIDS-Related Sclerosing CholangitisLaurent Hocqueloux, MD, Jean-Michel Molina, MD, PhD, and Anne Gervais, MDLaurent Hocqueloux, MDSaint-Louis Hospital; Paris, France 75010 (Hocqueloux)Saint-Louis Hospital; Paris, France 75010 (Molina)Beaujon Hospital; Paris, France (Gervais)Search for more papers by this author, Jean-Michel Molina, MD, PhDSaint-Louis Hospital; Paris, France 75010 (Hocqueloux)Saint-Louis Hospital; Paris, France 75010 (Molina)Beaujon Hospital; Paris, France (Gervais)Search for more papers by this author, and Anne Gervais, MDSaint-Louis Hospital; Paris, France 75010 (Hocqueloux)Saint-Louis Hospital; Paris, France 75010 (Molina)Beaujon Hospital; Paris, France (Gervais)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-132-12-200006200-00026 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Primary sclerosing cholangitis, chronic parasitic infection of the biliary ducts, and X-linked immunodeficiency are well-known risk factors for cholangiocarcinoma (1, 2). We report cholangiocarcinoma in a patient with AIDS-related sclerosing cholangitis.A 38-year-old homosexual man with AIDS was hospitalized for rapidly progressive jaundice and fever. He had a history of cytomegalovirus retinitis and AIDS-related sclerosing cholangitis that had developed 5 and 3 years before admission, respectively. When sclerosing cholangitis developed, the patient was severely immunodepressed (CD4+ cell count, 5 cells/mm3). The patient has been asymptomatic since undergoing endoscopic sphincterotomy 3 years ago. On admission, abdominal ultrasonography showed ...References1. De Groen PC, Gores GJ, LaRusso NF, Gunderson LL, Nagornay DM. Biliary tract cancers. N Engl J Med. 1999;341:1368-78. CrossrefMedlineGoogle Scholar2. Hayward AR, Levy L, Facchetti F, Notarangelo L, Ochs HD, Etzioni A. Cholangiopathy and tumors of the pancreas, liver and biliary tree in boys with X-linked immunodeficiency with hyper-IgM (XHIM). J Immunol. 1997;158:977-83. MedlineGoogle Scholar3. Palella FJ, Delaney KM, Moorman AC, Loveless MO, Fuhrer J, Satten GA, et al . Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med. 1998;338:853-60. CrossrefMedlineGoogle Scholar4. Ducreux M, Buffet C, Lamy P, Beaugerie L, Fritsch J, Choury A, et al . Diagnosis and prognosis of AIDS-related cholangitis. AIDS. 1995;9:875-80. CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAuthors: Laurent Hocqueloux, MD; Jean-Michel Molina, MD, PhD; Anne Gervais, MDAffiliations: Saint-Louis Hospital; Paris, France 75010 (Hocqueloux)Saint-Louis Hospital; Paris, France 75010 (Molina)Beaujon Hospital; Paris, France (Gervais) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInfections of the Biliary TractCholangitisCholangiocarcinoma in a Young Woman With Perinatally Acquired HIVAbdominal ultrasound findings in HIV and tuberculosisSecondary Sclerosing CholangitisCholangitisInfections of the Biliary TractCholangiocarcinoma presenting in an adolescent with vertically acquired HIV infectionCholangiocarcinoma and infection with TTV - case reportSclerosing cholangitis: A focus on secondary causesAIDS cholangiopathyCholécystite alithiasique de l’adulte : étiologies, diagnostic et traitement 20 June 2000Volume 132, Issue 12Page: 1006-1007KeywordsAIDSCholangiocarcinomaHighly active antiretroviral therapyParasitic diseasesPrimary sclerosing cholangitisRetinitisSurgerySurgical resectionTumor resectionUltrasound imaging ePublished: 15 August 2000 Issue Published: 20 June 2000 Copyright & PermissionsCopyright © 2000 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...