jimnoneill/paper-to-field-training huggingface dataset:
The Contemporary Catholic Teacher: A Reappraisal of the Concept of Teaching as a Vocation in the Catholic Christian Context

Field: Arts and Humanities (Social Sciences)

In exploring the concept of teaching as a vocation in Christian tradition, this book aims to articulate the essential interconnectedness between four elements: Christ as the foundation of Christian vocation - biblical perspectives, focusing particularly on the concepts of discipleship, emulation and charism The way in which that vocation has developed within Christian tradition - historical perspectives focusing on two Religious Orders Current critical scholarship concerning teaching as a vocation Vocation demonstrated in the perceptions and motivations of practitioners The research findings were then analysed in the light of the literature review and this was followed by a chapter in which conclusions were reached, structured around the principal elements of both the literature review and the empirical research. Based on these conclusions, a series of recommendations are put forward. focusing primarily on the maintenance of formation programmes both at Diocesan and Religious Order level, the challenge to address the complementary aspects of Christian vocation such as family commitments and the necessity to explore further what might be meant by 'integrity of life'.
The Influence of the Material used for Writing on the Transformation of the Sinhala Letters in Sri Lanka

Field: Arts and Humanities (Social Sciences)

It is important to look into the factors that have influenced the change of the Sinhala script through archeological and historical research. In the past, the Sinhala alphabet was composed of letters that had the shape of Asoka Brahmi script and some independently generated letters. The earliest Brahmi alphabet in Sri Lanka has evolved gradually up to now. Various factors were influenced when the Brahmi script transformed into the Sinhala alphabet. Among them, technological, political, environmental, socio-cultural, economic, and legal factors are the foremost. At present, Sri Lanka has also entered into the global economy and simultaneously, the attention has been focused on handling the language efficiently in a simple manner. In the process of evolving from the inscriptions to the computer in the present, the Sinhala script has achieved the status of being handled easily and simply with beautifully shaped letters, and further development can be expected with future technological achievements. Moreover, the number of letters has changed from time to time depending on the respective alphabet. When considering the Brahmi script that has developed in such a manner, some letters can be seen as gradually developed from their early shape, while some letters do not have any similarities with their present shape. Letters have acquired an angular shape when written on clay pots and in inscriptions, semi-circular shapes on metal plates, semi-circular and cursive shapes on Ola leaf, and a more circular shape when used in printing presses and computers.
Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Macrophage effector functions are influenced by their iron status and by shifts in the balance between type 1 Th1 and Th2 cells. To elucidate the influence of the Th2 cytokines IL-4 and IL-13 on macrophage iron metabolism, we investigated activated primary mouse macrophages and the murine macrophage cell line J774. Stimulation of J774 cells and primary macrophages with IFN-gamma/LPS activates the RNA binding affinities of iron regulatory protein-1 (IRP-1) and IRP-2 for iron-responsive elements, leading to translational repression of the iron storage protein ferritin. Activation of IRP-1 and IRP-2 is caused by increased formation of nitric oxide (NO) via stimulation of the inducible NO synthase by IFN-gamma/LPS. Treatment of macrophages with IL-4 and/or IL-13 before stimulation with IFN-gamma/LPS suppresses NO formation and IRP activation, with concomitantly enhanced ferritin synthesis despite a small reduction in ferritin heavy chain mRNA levels. The mRNA levels for the membrane receptor for iron uptake, transferrin receptor (TfR), decrease following stimulation with IFN-gamma/LPS, although IRP-mediated stabilization of the TfR mRNA would have been expected. This as yet unidentified proximal inhibitory signal by IFN-gamma/LPS is antagonized by IL-4 and/or IL-13, which leads to increased TfR mRNA expression in an IRP-independent manner. Thus, IL-4 and IL-13 regulate the iron metabolism of activated macrophages by at least two different pathways: first, by opposing NO-mediated IRP activation, thereby increasing ferritin translation; and second, by an IRP-independent augmentation of TfR mRNA expression. We suggest that IL-4 and IL-13 may enhance iron uptake and storage in activated macrophages and thereby contribute to down-regulation of macrophage effector functions.
Transport and storage of radioactive materials -- 1996. PVP-Volume 334

Field: Engineering (Physical Sciences)

The design of packaging for the transport of radioactive materials is a constantly evolving activity due primarily to new materials, new design approaches, and a better understanding of the regulations. As a consequence, the Operations, Applications and Components Committee organizes several sessions at the annual ASME PVP Division Conference to provide a forum for the discussion of the most recent trends in the transport and storage of radioactive materials. This publication is composed of technical papers that have been prepared for presentation at the 1995 Joint ASME/JSME Pressure Vessels and Piping Conference (July 23--27, Honolulu, Hawaii) during the sessions addressing the transport and storage of radioactive materials. The papers included were prepared to address engineering or regulatory issues associated with the transport or storage of radioactive materials. However, the subject matter can also have applications to solutions for problems in other areas. Individual paper have been processed separately for inclusion in the appropriate data bases.
Assessment of Standard Systems

Field: Decision Sciences (Social Sciences)

A main problem in reliability engineering is explaining results to professionals with little knowledge on reliability theory. This chapter presents the reliability data for items. With redundant systems, it is easier to write the probability that the system is not functioning if all items are not functioning. The use of Boolean algebra and probability formulae allows only basic systems to be analyzed. A more powerful method is to be used for getting analytical formulae for more complex systems: the Markovian approach. A series system is a configuration such that, if any one of the system items fails, the entire system fails. The chapter provides the value of the unrevealed unavailability average probability of dangerous failure on demand (PFDavg) for redundancy configurations, excluding common cause failures (CCFs) and assuming that the tests are not staggered.
Heaney,s hysterectomy for benign pathological conditions of uterus at tertiary care hospital in southern India

Field: Medicine (Health Sciences)

Introduction: Hysterectomy is one of the commonly performed gynaecological surgery. Vaginal hysterectomy is a natural orifice surgery where as laparoscopic hysterectomy is a minimally invasive procedure. Vaginal hysterectomy is associated with less morbidity, less operative time, short duration of hospital stay and reduced cost compared to laparoscopy. With increasing containment of health care costs and epidemic increase of non communicable medical disorders there is a need for performing vaginal hysterectomy in benign non prolapsed uteri especially in rural settings. Aims and Objectives: The objective of this study is to know the intra operative factors and to study the short term outcomes associated with non descent vaginal hysterectomy {Heaney,s hysterectomy}. Materials and Methods: This is prospective observational study conducted at MVJ Medical College and Research Hospital located in rural setting from January 2012 to December 2012. All the patients requiring hysterectomy for benign conditions not associated with uterine descent underwent non descent vaginal hysterectomy. Intra operative factors like blood loss, difficulty in delivery of uterus, bowel and bladder injuries, and conversion rates to laparotomy were noted. Post operative complications were noted. Results: Seventy two patients were planned to undergo non descent vaginal hysterectomy for various benign conditions. Vaginal hysterectomy was done successfully in 70 patients. The mean age was 45.6±3.4 and mean parity was 2.2±0.45. Dysfunctional uterine bleeding (55%) was the most common indication. Average duration of surgery was 45- 80 min. The requirement of post operative analgesia was minimal by the patient as there was no abdominal incision. Post operative complications were less. The duration of hospital stay was 3-5 days. Conclusions: Non descent vaginal hysterectomy is less invasive surgery. Less morbidity, lesser duration of hospital stay, cost effectiveness makes vaginal route as the choice
AIDS: A Psychosocial Research Agenda

Field: Psychology (Social Sciences)

This paper renews empirical findings relevent to four major research components of a research agenda for the study of psychosocial factors important to the spread and onset of AIDS. Although these four research components have only been investigated for a short period of time, considerable empirical support exists to show that study of psychosocial factors is essential to preventing and managing AIDS. Future research directions, which build on the current empirical findings, are outlined. These directions urgently need to be investigated if this epidemic is to be controlled.
Incubation and application of transgenic green fluorescent nude mice in visualization studies on glioma tissue remodeling.

Field: Medicine (Health Sciences)

This study showed that self-established EGFP athymic nude mice offered the possibility of visualizing tumorigenesis of human xenograft tumor, and the dual-color xenograft glioma model was of considerable utility in studying the process of tumor remodeling. Based on this platform, mutual interactions between glioma cells and host tissues could be observed directly to further elucidate the development of tumor microenvironment.
Photoluminescence Study of InAs Quantum Dots and Quantum Dashes Grown on GaAs (211)B

Field: Physics and Astronomy (Physical Sciences)

InAs self-organized quantum dots (QDs) and quantum dashes (QDHs) were grown by molecular beam epitaxy on GaAs (211)B substrates. QDs with bimodal size distribution were formed at lower growth temperatures, whereas QDHs were observed at higher growth temperatures. Photoluminescence (PL) intensity and peak position of QDs and QDHs showed similar temperature dependence, whereas the excitation density dependence of the PL peak intensity and the PL peak energy of the two nanostructures was different. The blue shift in QDH peak energy with the increase of the excitation density is suggested to be due to the existence of the piezoelectric field in InAs QDHs.
Applications of Lead Isotopes to Ore Geology, Metallogenesis and Exploration

Field: Earth and Planetary Sciences (Physical Sciences)

Abstract Although lead isotopes are most commonly used to date geological events, including mineralizing events, they also can provide information on many aspects of metallogeny and can be directly used in mineral exploration. Lead isotope data are generally reported as ratios of radiogenic isotopes normalized to the non-radiogenic isotope 204 Pb (e.g. 206 Pb/ 204 Pb, 207 Pb/ 204 Pb and 208 Pb/ 204 Pb). These ratios can be used in exploration to characterize the style of mineralization, metal (i.e. Pb) source and as vectors to ore. When combined with lead isotope evolution models, the data can be used to indicate the age and tectonic environment of mineralization. The raw ratios and evolution models enable calculation of derived parameters such as μ ( 238 U/ 204 Pb), κ ( 232 Th/ 238 U) and ω ( 232 Th/ 204 Pb), which provide more information about tectonic setting and can be contoured to identify crustal boundaries and metallogenic provinces. In some cases, tectonic boundaries, mapped using gradients in μ and other derived parameters, are fundamental controls on the distribution of certain deposit types in space and time. Moreover, crustal character, as determined by lead and other radiogenic isotopes (e.g. Nd) can be an indicator of province fertility for many deposit types. The development of cost effective analytical techniques and the assembly of large geo-located datasets for lead and other isotope data has enabled significant advances in understanding the genesis and localization of many deposit type, particularly when the isotopic data are integrated with other independent datasets such as potential field, magnetotelluric, passive seismic and geochemical data.
<title>Two Technologies Generating Aspherical Surfaces: Thermal Polishing Of A Glass-Grain-Settled Surface And Transparent Single-Point Turning Of Glass</title>

Field: Engineering (Physical Sciences)

Thermal polishing of a settled layer of glass grains on a ground aspherical substrate by heat transfer is described. The layer-glass and substrate-glass have the same index of refraction. A phenomenological description is given of transparent turning of optical glasses by a single-point tool. The glass is turned at an elevated temperature at about the American softening temperature. A process combining abrasive turning and viscous relaxation makes transparent turning of a limited number of glasses possible.
Characterization of Cysteine Cathepsin Expression in the Central Nervous System of Aged Wild-Type and Cathepsin-Deficient Mice

Field: Neuroscience (Life Sciences)

The association of cathepsin proteases in neurobiology is increasingly recognized. Our previous studies indicated that cathepsin-K-deficient (Ctsk−/−) mice have learning and memory impairments. Alterations in cathepsin expression are known to result in compensatory changes in levels of related cathepsins. To gain insight into the therapeutic usefulness of cathepsin inhibitors in aging individuals with osteoporosis or neurodegenerative diseases, we studied for variations in cathepsin expression and activity in aged (18–20 months) versus young (5–7 months) wild-type (WT) and cathepsin-deficient mice brains. There were age-dependent increases in cathepsin B, D, and L and cystatin C protein levels in various brain regions, mainly of WT and Ctsk−/− mice. This corresponded with changes in activity levels of cathepsins B and L, but not cathepsin D. In contrast, very little age-dependent variation was observed in cathepsin-B- and cathepsin-L-deficient mouse brain, especially at the protein level. The observed alterations in cathepsin protein amounts and activity are likely contributing to changes in important aging-related processes such as autophagy. In addition, the results provide insight into the potential impact of cathepsin inhibitor therapy in aged individuals, as well as in long-term use of cathepsin inhibitor therapy.
Chronic Administration of Dimebon does not Ameliorate Amyloid-β Pathology in 5xFAD Transgenic Mice

Field: Neuroscience (Life Sciences)

Dimebon has been tested as a potential modifier of Alzheimer's disease (AD), resulting in mixed clinical trial outcomes. Originally utilized as an antihistamine, Dimebon was later found to ameliorate AD symptoms in initial human trials. Although subsequent trials have reportedly failed to replicate these finding, there is a growing body of evidence that Dimebon might be neuroprotective in certain models of neurodegeneration. The precise mechanism by which Dimebon is thought to act in AD is unclear, though changes in receptor activity, mitochondria function, and autophagy activity have been proposed. It is thus necessary to test Dimebon in transgenic animal model systems to determine if and how the drug affects development and manifestation of pathology, and which pathogenic processes are altered. In the present study we treated mice harboring five familial mutations associated with hereditary AD (5xFAD line) with a chronic regime of Dimebon. The compound was not found to improve the general health or motor behavior of these mice, nor prevent accumulation of Aβ peptides in the brain. Modest changes in response to an anxiogenic task were, however, detected, suggesting Dimebon might improve behavioral abnormalities and cognition in disease in a mechanism independent of protecting against amyloidosis.
Effectiveness of a physical activity intervention in preschoolers: A cluster‐randomized controlled trial

Field: Medicine (Health Sciences)

Several activity interventions in preschool settings exist, but little attention has been paid to effects on hemodynamic factors. The study aimed to assess the effectiveness of an exercise program on health‐related outcomes including blood pressure (BP) and markers of vascular function in preschoolers, with focus on socioeconomic background. This study is a cluster‐randomized controlled trial, with preschool as unit of randomization and children as unit of analysis. Preschools with 3‐ to 6‐year‐old children, stratified by social area, were randomly allocated to: intervention (three clusters, n = 92) including 2 d·wk −1 /45 min (6 months) exercise lessons or control (two clusters, n = 43). In total, 135 children (4.8 ± 0.8 y) had minimum one outcome measurement at baseline and follow‐up. Primary outcome: peripheral BP. Secondary outcomes: central BP, pulse wave velocity (PWV), BMI, waist circumference, physical activity measures, motor skills. Maternal education was used as an indicator of socioeconomic status. Mixed models were applied to evaluate differences in mean change. Group allocation had no effect on primary or secondary outcomes. However, the intervention was effective in reducing increases in peripheral systolic BP (−3.4 mm Hg; 95% CI: −6.6; −0.2; P = 0.037), central systolic BP (−3.8 mm Hg; −6.4; −1.1; P = 0.006), and PWV (−0.1 m/s; −0.2; −0.0; P = 0.045) among children whose mothers had the lowest educational level. We found no evidence for effectiveness of a 6‐months preschool‐based exercise program on hemodynamics, anthropometrics, activity, or motor skills, but lack of process evaluations and poor fidelity preclude interpretation of the causal relation. However, the results indicate that children from lower social backgrounds could benefit from early exercise‐promoting interventions.
REPRESENTASI DESAIN INTERIOR PUSAT KEBUDAYAAN KOREA SELATAN DI JAKARTA UNTUK MENDUKUNG PENDIDIKAN BERKUALITAS

Field: Arts and Humanities (Social Sciences)

South Korean culture, such as history, K-pop, K-drama, K-beauty, K-food, and so on, has gained the attention of Indonesian people of various communities and ages. Simultaneously with the increasing interest of the Indonesian people in entertainment, beauty, food & beverage, and other sectors from South Korea, the Korean industry in Indonesia is also increasing. The existence of the South Korean Cultural Center is currently still limited to being a Korean language center and does not yet present South Korean history, art, and technology which are of great interest to the Indonesian public today.This study aims to create an interior design concept for the South Korean Cultural Centerthat complies withits vision and mission, create a space and circulation program that suits the activities and behavior of users, and create a green design concept. This study adapts the 4th point of the Sustainable Development Goals regarding the Quality of Education and uses a qualitative descriptive research method.This design carries a concept with the theme "Two sides of Korea" which shows two sides of South Korea from two different eras: the past and present, by displaying a natural, warm, and dynamic image. In this design, the author chooses a contemporary South Korean style while still paying attention to green design.
Cardiac lymphoma requiring surgical resection

Field: Medicine (Health Sciences)

A 62-year-old woman was admitted to the emergency department with fever, cough, dyspnea, and weight loss of 5 kg in 6 months. Computed tomography revealed numerous lung nodules, masses in both breasts, multiple enlarged lymph nodes, and large low-density areas in the right atrium. Transthoracic echocardiography showed a 35-mm hypoechoic mass in the right atrium, extending like a stalk from near the superior vena cava (SVC), which moved significantly with the heartbeat (Figure 1). Breast biopsy revealed a diffuse large B-cell lymphoma (DLBCL). Intracardiac tumor resection was performed before chemotherapy to prevent tumor embolism or valvular obstruction. The surgery was performed through a midline sternal incision. When the right atrium was incised with extension in the SVC direction, the inside of the right atrium was filled with a tumor with good mobility (Figure 2). The tumor was firmly adherent near the junction of the right atrium and the SVC. Subsequent chemotherapy was expected to shrink the tumor; therefore, the tumor was carefully resected so that the sinus node could remain. The resected tumor consisted of a 35-mm-large mass and the portion adherent to the right atrium, which was removed in pieces. Histologic analysis of the resected tumor revealed DLBCL. The patient was started on chemotherapy for stage IV DLBCL 10 days after surgery. She has achieved complete remission, and no arrhythmia or loss of cardiac function has occurred. DLBCL treatment is mainly systemic chemotherapy and, in some cases, irradiation. However, antecedent urgent surgery may be required in some cases when the tumor could cause life-threatening events [1, 2]. Our patient had no obvious sign of heart failure, but her tumor occupied most of the right atrium and protruded into the right ventricle during diastole with great mobility. There were concerns that the chemotherapy would detach the mass in the right atrium from the SVC and cause tumor embolization or entrapment of the tricuspid valve. Therefore, we decided to perform intracardiac tumor resection prior to chemotherapy. In addition, the goal of surgery was not complete tumor resection but prevention of fatal cardiovascular events; therefore, we tried to preserve normal cardiovascular tissue. We were able to successfully preserve the sinus node at the site of tumor adhesion and the patient has been free of arrhythmia and cardiac dysfunction since the surgery. The authors thank the medical and nursing staff at the Kobe City Medical Centre General Hospital. The authors received no specific funding for this work. The authors declare they have no conflicts of interest. Publication of this case report does not require approval from the institutional review board of our hospital. Written informed consent for publication was obtained from the patient.