jimnoneill/paper-to-field-training huggingface dataset:
The role of coronary artery reimplantation for anomalous right coronary artery originating from the opposite sinus of Valsalva: preliminary outcomes and insights from a Latin American country

Field: Medicine (Health Sciences)

Abstract Despite promising results, reimplantation appears to have fallen into oblivion among the multiple possible approaches for repairing anomalous coronary arteries. We describe the outcomes of 12 patients with an anomalous right coronary artery originating from the opposite sinus of Valsalva with an interarterial course who were surgically treated with this technique between 2018 and 2023 in 2 institutions in Bogota, Colombia. We provide preliminary evidence of the value reimplantation as a more than suitable technique, particularly in resource-constrained settings. It offers high rates of control of symptoms and functional class recovery while assessing all potential high-risk features, with a low risk of complications, even in middle-aged patients. We also advocate using noninvasive anatomical descriptions and patient symptoms over inducible ischaemia tests in decision making.
Trends in the Incidence and Management of Acute Myocardial

Field: Medicine (Health Sciences)

Background-—The American Heart Association Get With the Guidelines (GWTG) program has improved care quality of acute myocardial infarction (AMI) with important implications for other countries in the world. This study evaluated the incidence and care of AMI in Taiwan and assessed the compliance of GWTG in Taiwan. Methods and Results-—We used the Taiwan National Health Insurance Research Database (1999–2008) to identify hospitalized patients ≥18 years of age presenting with AMI. The temporal trends of annual incidence and care quality of AMI were evaluated. The age-adjusted incidence of AMI (/100 000 person-years) increased from 28.0 in 1999 to 44.4 in 2008 (P&lt;0.001). The use of guideline-based medications for AMI was evaluated. The use of dual antiplatelet therapy (DAPT) increased from 65 % in 2004 to 83.9 % in 2008 (P&lt;0.001). Angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) was used in 72.6%
Single-stage power factor correction AC/DC converter

Field: Engineering (Physical Sciences)

Power factor correction (PFC) is the capacity of generating or absorbing the reactive power produced by a load. The major industrial loads have an inductive power factor. The current tends to go beyond the power is usually used for the power conversion. This paper introduces a forward single-stage power factor correction AC/DC converter which effectively improves the power factor up to PF = 0.999. The simulation and experimental results verified our design.
The Current Status of Methodological Support of Corporations Risk Management

Field: Decision Sciences (Social Sciences)

The study concluded that each of the methods of risk management has its own characteristics. At the same time, a large number of methods of risk management, each of which has its advantages and disadvantages, as well as its domain the most effective use, raises questions about the combination of different measures. The combination of selected methods is made in the form of software risk management. This study indicates insufficient research risk management techniques, lack of classification of risk management techniques, confirms the need for a classification of risk management techniques.
New or rare Madagascar tiger beetles— 9. Two new species of the genus Physodeutera Lacordaire, with revised keys to the species of subgenera Diarrhiza Jeannel and Minideutera Moravec (Coleoptera: Cicindelidae)

Field: Agricultural and Biological Sciences (Life Sciences)

This dataset contains the digitized treatments in Plazi based on the original journal article Moravec, Ji Ř Í (2004): New or rare Madagascar tiger beetles— 9. Two new species of the genus Physodeutera Lacordaire, with revised keys to the species of subgenera Diarrhiza Jeannel and Minideutera Moravec (Coleoptera: Cicindelidae). Zootaxa 775: 1-12, DOI: 10.5281/zenodo.158446
Spices Biotechnology: Opportunities and Challenges

Field: Agricultural and Biological Sciences (Life Sciences)

<div>Spices have been used since ancient times as a flavoring agent as well as an</div><div>important medicinal resource. Biotechnology, using strategies such as cell, organ, and</div><div>tissue culture, genetic engineering, and the application of nucleic acid markers can</div><div>escalate the productivity and efficiency of spices. Cell, tissue, and plant organ culture</div><div>have enabled the rapid and mass reproduction of many disease-free spice plants, which</div><div>are uniform genetically and qualitatively. In recent years, cell and limb suspension</div><div>(stem and hair roots) have been considered for producing secondary metabolites and</div><div>for studying the biosynthesis pathway of metabolites. Plant genetic engineering has</div><div>helped in the genetic identification and manipulation of enzymes of the biosynthetic</div><div>pathway of secondary metabolites. Gene transformation has improved the production</div><div>of secondary metabolites that have yield limitations. Molecular markers are powerful</div><div>tools for accurately identifying important medicinal species, examining genetic</div><div>diversity, classifying hereditary reserves, and determining their genetic map</div><div>irrespective of their age, physiological, and environmental conditions. Next-generation</div><div>sequencing (NGS) methods like restriction-site-associated DNA sequencing (RAD-seq)</div><div>have revolutionized the study of genetic diversity, and the enzymes and genes implied</div><div>in the secondary metabolites biosynthetic pathways can be studded by transcriptome</div><div>profiling (RNA-seq). The ground-breaking genome editing techniques like Clustered</div><div>Regularly Interspaced Short Palindromic Repeats (CRISPR), sequence-specific</div><div>nucleases of transcription activator-like effector nucleases (TALENs), and zinc-finger</div><div>nucleases could help in customizing the plants according to the requirements. This</div><div>article provides an overview of various biotechnology solutions that increase the</div><div>quality and productivity of spice plants.</div>
A 900 MHz ladder-type SAW filter duplexer

Field: Engineering (Physical Sciences)

A low-cost hybrid-integrated SAW filter duplexer consisting of receiver top filter, transmitter final-stage filter and antenna terminal has been developed. The prototype design was oriented at the GSM system specifications in the 900 MHz-band. Three-stage ladder-type SAW filters have been designed to perform the duplexing function by the use of only one transmission line. The complete duplexer has an insertion loss of 1.2 dB in the Tx path (Tx) and 2.1 dB in the Rx path (Rx). The 3 dB-bandwidth is 40.1 MHz (Tx) and 47.4 MHz (Rx), respectively.
Early Childhood Sex Education: Case Study in Kindergarten Indonesia

Field: Social Sciences (Social Sciences)

Purpose of the study: Early childhood sex education in kindergarten can support the needs of children to acquire knowledge of the basics of Islamic sex education, attitudes and behavior of noble morality.
Methodology: This research is a qualitative study of the case study approach. Data collection techniques with participant observations, interviews, documentation, archives, live observations, and physical devices. Data analysis techniques using the model's interactive analysis are data reduction, data presentation, and withdrawal as well as conclusion or verification testing. Data validity testing with source and technique triangulation.
Main Findings: Study results showed early childhood sex education could be developed using theme learning and teachers using ways that Islam has taught in the implementation of sex education.
Applications of this study: Headmistress and staff teachers are expected to provide information and introduce early sex education so that they can develop all aspects of the child's personality.
Novelty/Originality of this study: In this study is said that early childhood education that is performed educatively and more aesthetic can give understanding about identity and limbs, can distinguish both good and bad, have a shame, accustomed to protect aurat from the views of others, being able to maintain privacy or refuse to harm a child.
Delayed end ejection increases isovolumic ventricular relaxation rate in isolated perfused canine hearts.

Field: Medicine (Health Sciences)

We sought to determine the ejection variables that are principally responsible for increases in isovolumic ventricular relaxation rate observed with increases in stroke volume. In nine isolated canine hearts, left ventricular ejection was controlled by patterns specially designed to isolate the ejection parameters most critical to isovolumic relaxation rate. When stroke volume was augmented by increases in end-diastolic volume (EDV) with end-systolic volume (ESV) held constant, isovolumic ventricular relaxation rate was unchanged, as gauged by the time constants of single-exponential fits to decaying pressure. In contrast, when ESV was decreased with EDV held constant, isovolumic relaxation time constants decreased significantly, from approximately 100 to 70 msec (protocol I). The important difference in these two situations might have been that the time of end ejection was delayed in the case with faster isovolumic relaxation. To rule out other parameters that may have influenced isovolumic relaxation, ejection velocity was varied in another protocol (protocol II) by either delays in time of the onset of ejection or advances in end-ejection time, always with constant ESV and EDV. Here isovolumic relaxation was progressively slowed as end ejection occurred earlier, whereas isovolumic relaxation rate was insensitive to changes in the onset of ejection, consistent with the unique importance of end ejection to isovolumic relaxation. In fact, our analysis reveals the remarkable finding that changes in isovolumic relaxation time constant produced by either protocol I or protocol II could be related quantitatively to end ejection by a single curve.(ABSTRACT TRUNCATED AT 250 WORDS)
Flow diverter stents with hydrophilic polymer coating for the treatment of acutely ruptured aneurysms using single antiplatelet therapy: Preliminary experience

Field: Medicine (Health Sciences)

Background The use of flow diverter stent (FDS) has limitations in cases of subarachnoid haemorrhage caused by ruptured aneurysm, due to the need for double antiplatelet therapy and the delay in the aneurysm occluding. The p48 MW and the p64 MW (Phenox) are available with Hydrophilic Polymer Coating (HPC), that reduces the risk of thrombus formation. Purpose of this study is to evaluate the safety and efficacy of p48 and p64 MW HPC with single antiplatelet therapy for the acute treatment of ruptured aneurysm. Methods We retrospectively evaluated all patients treated for acutely ruptured aneurysms with a p48 MW HPC or p64 MW HPC from October 2019 to April 2020 using single antiplatelet therapy. For each patient, we considered demographic and aneurysm-related data, clinical presentation, size and location of the implanted flow diverter stent, intra- and post-procedural complications, aneurysm occlusion. Results Seven patients were included. The ruptured aneurysms were four saccular, two blister-like and one dissecting, six in the anterior and one in posterior circulation. No intraprocedural stent thrombosis and rebleeding was observed. In two cases the aneurysm is completely excluded, in one patient it was found only neck perfusion, in three cases there were mild reduction of the sac and in one case there was a persistent perfusion. No patients needed retreatment in this series. Conclusion In our experience, FDS HPC appears a potential treatment option in selected cases. Our study is limited by small population and short-term follow-up. We report our preliminary data, but further investigations are necessary.
Detection of 1,N6-propanodeoxyadenosine in acrolein-modified polydeoxyadenylic acid and DNA by 32P postlabeling.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The interaction of acrolein, an alpha,beta-unsaturated aldehyde, with polydeoxyadenylic acid and DNA has been investigated using 32P-postlabeling analysis. In preliminary experiments, polydeoxyadenylic acid was incubated with excess acrolein and then digested to 3' monophosphates prior to transfer of 32P from [gamma-32P]ATP with T4 polynucleotide kinase. The 3',5'-bisphosphates were 3'-dephosphorylated prior to two-dimensional thin layer chromatography on polyethyleneimine-cellulose layers. Autoradiography provided evidence for the formation of one extra spot of radioactivity, compared to the control. To determine the adduct structure, deoxyadenosine-5'-monophosphate was incubated with a 3-fold excess of acrolein. This material was mixed with a 32P-labeled digest of acrolein-polydeoxyadenylic acid, and the sample was analyzed by ion-pair high performance liquid chromatography. The spot of 32P observed by thin layer chromatography co-eluted with the major product of the acrolein nucleotide reaction mixture, which was purified by ion-pair high performance liquid chromatography. Two-dimensional nuclear magnetic resonance spectroscopy and mass spectrometry showed the adduct to be 3-(2'-deoxyribosyl-5'-monophosphatyl)-7,8,9-trihydro-9-hydro xy- pyrimido[2,3-i]purine(1,N6-propanodeoxyadenosine-5'-monophosphate) . High performance liquid chromatography was used to fractionate digests of acrolein-modified DNA prior to detection of this exocyclic adduct by 32P-postlabeling.
Delay Analysis of Spatio-Temporal Channel Access for Cognitive Networks

Field: Computer Science (Physical Sciences)

Most channel access schemes for cognitive radio only consider using the idle periods of the primary users. Such schemes are not using the spectrum efficiently, since transmission opportunities also arise when a primary transmitter is active but its corresponding primary receiver is far away from the cognitive user. By detecting the signal power of the acknowledgments, a cognitive user is able to estimate the distance and channel condition between the primary receiver and itself. Then if the primary receiver is far away, the cognitive user can transmit simultaneously with the primary transmitter without affecting the primary link. Based on this idea, the spatio-temporal channel access scheme, utilizing both idle periods and spatial reuse, can be applied. This paper provides fundamental analysis of the channel access delays and shows the advantage of using the spatio-temporal access scheme in the carrier sense multiple access (CSMA)-based network with bi-directional links.
Unusual Symptomatic Aortic Arch Anomalies

Field: Medicine (Health Sciences)

Anomalies of the aortic arch are not uncommon. Quite often they may be suspected from the standard four chest films, with barium in the esophagus, and definitively demonstrated by angiocardiography. Those anomalies forming vascular rings, e.g., the double aortic arch, have been well documented in the literature. The purpose of this report is to illustrate three anomalies of the aortic arch and its brachiocephalic branches: anomalous innominate artery, the cervical aortic arch, and congenital stenosis of one or more of the brachiocephalic vessels. The second and third of these have not been previously documented in the radiologic literature. Most vascular rings and malformations of the aortic arch can be related to either a persistence or abnormal regression of one or more of the six original paired primitive aortic arches. The caudal descent of the heart occurs as the first two arches regress and disappear. Edwards (1, 2), in his simplified classification, uses the basic embryologic pattern of two arches, a dorsal and ventral aorta, and a ductus between to explain most of the anomalies by persistence or regression at multiple locations in this system. The three aortic-arch anomalies of this communication may not be recognized on conventional radiography. The symptoms and signs of the first two types relate to compression of the esophagus and/or tracheobronchial tree, usually evident shortly after birth. They may be so severe as to be life-threatening or they may be minor and never clinically significant. The following events may be included in the clinical picture; coughing, choking, stridor, "apneic spells," and aspiration and recurrent pneumonia (3). The third type of anomaly may not cause significant clinical distress but be confusing and annoying because of murmurs and pulse abnormalities. It may be mistaken for a congenital heart defect, as in our Case III below. Anomalous Innominate Artery Case I: This male infant was the product of a 9-month full-term pregnancy. The child was apneic during the newborn period, but this condition improved, and physical signs did not again appear until respiratory distress occurred at one month of age. Subsequently, he was hospitalized on four separate occasions for respiratory distress. Each time improvement followed symptomatic therapy. On his fifth hospital admission, at the age of thirteen months, the child again presented with stridor, rhonchi, and subcostal retractions. The respiratory rate was 36 per minute. There was no cyanosis. No significant laboratory abnormalities were found. The lungs were clear on auscultation. Cultures of the nose and throat grew alpha Streptococcus and 1+ Staphylococcus aureus. The blood culture showed no growth. Oral fluids and Ampicillin were administered, and the child was placed in a croupette with oxygen and mist. On the sixth hospital day, he became afebrile without respiratory distress. The roentgen findings on this admission are shown in Figures 1–3.
[Plasmablastic plasma cell myelomas with abnormal expression of CD3: report of a case].

Field: Medicine (Health Sciences)

患者男，42岁。5年前外院确诊为多发性骨髓瘤ⅢA（IgA-LAM型），化疗后4个月余，因发现左腰背部肿物入院。入院后行肿物穿刺活检，镜下见胞质丰富的肿瘤细胞弥漫密集，浸润性生长，侵及周围脂肪组织。肿瘤细胞圆形或卵圆形，胞质嗜碱性或嗜双色性，核深染、圆形偏向一侧，部分核仁明显，核分裂象易见，未见坏死及核碎屑。免疫组织化学检测肿瘤细胞呈：CD3、CD38、CD138、CD56、MUM1、Lambda阳性，Ki-67阳性指数达90%，CD20、Kappa、EB病毒编码的小RNA（EBER）阴性。诊断为高级别浆细胞肿瘤；结合多发性骨髓瘤病史，考虑浆母细胞型骨髓瘤并反常表达CD3。.
Structure-based Discovery of Potential Inhibitors Targeting Sodium-bile Acid Co-transporter of Carcinogenic Liver Fluke Clonorchis Sinensis

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Abstract Background : Clonorchis sinensis requires bile acid transporters as this fluke inhabits bile juice-filled biliary ducts, which provide an extreme environment. C. sinensis sodium-bile acid co-transporter (CsSBAT) is indispensable for survival in the final host, as it circulates taurocholate and prevents bile toxicity in the fluke; hence, it is recognized as a useful drug target. Results : In the present study, using structure-based drug discovery approach, we presented inhibitor candidates targeting a bile acid-binding pocket of CsSBAT. CsSBAT models were built using comparative tertiary structure modeling based on a bile acid transporter template (PDB ID: 3zuy and 4n7x), and were applied into AutoDock Vina for competitive docking simulation. First, potential compounds were identified from PubChem (holding more than 100,000 compounds) by applying three criteria: i) interacting more favorably with CsSBAT than with a human homolog, ii) intimate interaction to the inward- and outward-facing conformational states, iii) binding with CsSBAT more preferably than natural bile acids. Second, two compounds were identified following Lipinski’s rule of five. Third, another two compounds of molecular weight higher than 500 Da (Mr > 500 Da) were presumed to efficiently block the transporter via a feasible rational screening strategy. These four inhibitor candidates exhibited least toxicity that may enhance drug-likeness properties. Conclusion : It is proposed that four compounds act as potential inhibitors toward CsSBAT, and further studies are warranted for drug development process against clonorchiasis.
Integrating Gender into Canadian Internet Policy: From the Information Highway to the Digital Economy

Field: Social Sciences (Social Sciences)

Abstract This article provides an overview of gender and Internet policy in Canada from the mid-1990s to the present day. It first traces early federal policy (Fourth World Conference on Women, federal plan for gender equality, and the Information Highway Advisory Council [IHAC]). Turning to the 2000s, the article reviews Canada's influence in international initiatives (World Summit on the Information Society). The article then reviews Conservative government initiatives (digital economy agenda, Digital Canada 150), illustrating a decline for digital inclusion. With a new Liberal government, the article concludes with areas of engagement by government and civil society toward digital and gender inclusion.
PREDICTING THE MORTALITY AND MORBIDITY IN ACUTE PANCREATITIS USING RANSON'S AND GLASGOW'S SCORING INDICES; A PROSPECTIVE OBSERVATIONAL STUDY

Field: Medicine (Health Sciences)

Introduction: Acute pancreatitis is a sudden and severe inflammatory condition of the pancreas, which can result in significant morbidity and mortality. Accurate prognostic tools are essential for predicting the severity of the disease and guiding clinical management. Two commonly used scoring systems are Ranson's and Glasgow's scores, both of which are used to assess the severity of acute pancreatitis and predict patient outcomes. Objective: This study aimed to compare the accuracy of Ranson's and Glasgow's scoring systems in predicting the severity of acute pancreatitis, organ failure, and the need for ICU care. A prospective study was conducted on 80 patients with acu Methods: te pancreatitis at Bangalore medical college and research institute. Patients were assessed using Ranson's and Glasgow scores at admission and after 48 hours. Outcomes, including organ failure and mortality, were recorded. These outcomes were then compared with the predictions of both scoring systems to evaluate their accuracy in predicting patient prognosis. In a study of 80 patients with acute pancreatitis, 72.5% Results: were diagnosed with mild cases, while 27.5% had severe forms. Both Ranson and Glasgow scores showed moderate correlation with CT-based severity assessments. A Ranson score of ≥3 demonstrated 66.7% sensitivity and 83.1% specificity, whereas a Glasgow score of ≥3 achieved 100% sensitivity but 64.9% specificity. Mortality, reported at 3.75%, was observed exclusively in patients with persistent organ failure. G Conclusion: lasgow's scoring system is considered a more practical and accurate tool than Ranson's score for predicting the severity of acute pancreatitis. Its simplicity, efficiency, and ease of use make it a valuable prognostic index in clinical practice, providing improved accuracy and better prediction of patient outcomes.