jimnoneill/paper-to-field-training huggingface dataset:
The Papanicolaou Smear as a Diagnostic Tool in Male Trichomoniasis

Field: Medicine (Health Sciences)

No AccessJournal of Urology1 May 1972The Papanicolaou Smear as a Diagnostic Tool in Male Trichomoniasis Jack L. Summers and Manley L. Ford Jack L. SummersJack L. Summers More articles by this author and Manley L. FordManley L. Ford More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)61155-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1972 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 107Issue 5May 1972Page: 840-842 Advertisement Copyright & Permissions© 1972 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Jack L. Summers More articles by this author Manley L. Ford More articles by this author Expand All Advertisement PDF downloadLoading ...
Being tough, staying good, and playing inside the box : an ethnographic case study of one boy's multimodal textmaking

Field: Arts and Humanities (Social Sciences)

This study of multimodal textmaking is focused on how resources from home and from school are used by one child in the middle years of elementary school. Kyle is the primary participant in this ethnographic case study, which spanned two school years. Analysis focused on how texts change, how resources and identities are constructed and reconstructed, and which texts and textmaking practices are valued and which are not. In response to the need to understand more fully how hybrid or ‘relocalized’ (Pennycook, 2010) texts are made, this study undertook an examination of a wide range of textmaking processes. Kyle’s use of the cultural resources of professional wrestling, amongst others, to make narrative and performative hybrid texts, is traced. His ‘rescripting’ of everyday experiences, in playful and parodic ways, is explored. Kyle’s writing within a mandated writing process, performance-based assessment is also examined and a sociocultural understanding of creativity is proposed. Insight into permeability of home and school boundaries is offered. An expanded definition of text to include multimodal forms suggests that all texts are multimodal, but also that many children are excluded from successful textmaking at school because the modes, forms, and resources with which they are familiar or have had success, are not included amongst the valued texts at school (Luke, 1997; Marsh, 2006; Nixon & Comber, 2006). Powerful practices and interpersonal influences are made visible in a way that is not possible when only polished or final versions of texts are considered. The potentials and possibilities offered by play and improvisation within textmaking, both in and out of school, are emphasized.
Tibial Revision Knee Arthroplasty: Influence of Modular Stems on Implant Fixation and Bone Flexibility in AORI Type T2a Defects

Field: Medicine (Health Sciences)

Background Due to the varying bone defects presented to surgeons during revision total knee arthroplasty, modular implant systems are preferred over standard implant designs. However, every implant combination (sleeves, stems and augments) can affect the fixation in different ways and thus influence the long-term outcome. We therefore aimed to analyze the effect of large metaphyseal sleeves with and without short modular stems on implant fixation and bone flexibility of a modular tibial revision knee system. Methods A new tibial revision implant (Attune RP Revision; DePuy Synthes) with a sleeve was compared to a sleeve/stem combination implanted in synthetic bones with Anderson Orthopaedic Research Institute (AORI) Type T2a defects and also compared to an intact bone. Implant-bone-interface micromotions and bone deformations during standardized load application were measured using a digital image correlation system. Results The lowest relative micromotions were measured more distally for stemmed implants, and more proximally for the stemless group. When compared to an intact bone, there is increased proximal bone deformation in the stemless group. Conclusions Using a short stem in addition to a tibial revision implant with a metaphyseal sleeve in a moderate bone defect provides for more natural bone deformation. Although the main fixation area was shifted distally, relative micromotions were reduced. Based on this biomechanical study, the use of diaphyseal short stems with metaphyseal sleeves seems to be beneficial in terms of the initial implant fixation and for its flexibility, which is similar to that of intact bones in the case of AORI T2a defects.
Juvenile myoclonic epilepsy of Janz

Field: Medicine (Health Sciences)

We studied 43 patients, aged 15 to 69 years, whose convulsive seizures were uncontrolled because the syndrome of juvenile myoclonic epilepsy was not recognized. Awakening myoclonic jerks appeared with tonic-clonic (18 patients), clonic-tonic-clonic (24 patients), and absence seizures (17 patients), with a mean age at onset of 13.6 years. Generalized seizures were present in relatives of 17 patients. All patients had diffuse 3 1/2- to 6-Hz multispike-wave complexes. Valproic acid stopped convulsions in 86% of patients. After being free of seizures for 2 years, withdrawal of valproic acid was followed by relapse of convulsions in 12 patients.
The Ocular Albinism Type 1 (OA1) Gene Controls Melanosome Maturation and Size

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The findings indicate that Oa1 is involved in the regulation of melanosome maturation at two steps. Acting at early maturation stages, Oa1 controls the abundance of melanosomes in RPE cells. At later stages, Oa1 has a function in the maintenance of a correct melanosomal size. This study helps to define ocular albinism type 1 as a defect in melanosome organellogenesis and not in melanin production.
Modified generalized Chen distribution, estimation and application using econometrics data

Field: Mathematics (Physical Sciences)

In this study, a variant of the generalized Chen (GC) distribution with parameters α, β, γ, δ, and λ, termed the Modified Generalized Chen (MGC) distribution, was introduced. The study evaluated several Chen distribution variants theoretically, focusing on the MGC distribution. Variants considered include the Generalized Chen (GC), Half-Cauchy Chen (HCC), New Extended Chen (NEC), and Exponentially Generalized Modified Chen (EGMC) distributions. The objectives of the study was to derive the probability density function (PDF) and cumulative density function (CDF) of the MGC distribution, determine its statistical properties and reliability characteristics, compare these properties and characteristics to existing distributions, and empirically evaluate its performance. The study developed unique expressions for the PDF, CDF, survival function, and hazard function of the MGC distribution. By evaluating PDFs and performance measures such as the Akaike Information Criterion (AIC), Bayesian Information Criterion (BIC), and mean square error (MSE) across various datasets, the MGC distribution consistently demonstrated superiority over other variants. The MGC distribution offers improved model fit, predictive accuracy, and interpretability without sacrificing simplicity. The dataset employed in this study was the secondary data, encompassing economic indicators from 1981 to 2021 and public health expenditure data for Nigeria and Ghana from 1995 to 2014. Statistical analyses revealed that on the average, the MGC distribution outperforms others, with superior average AIC (-509.95), BIC (-510.49), and MSE (499.89) measures across the datasets considered in the study. This superior performance indicates better fit and accuracy in predicting economic and public health outcomes, offering valuable insights for policymakers and researchers. The study underscores the importance of adopting flexible and interpretable distribution models like the MGC distribution to enhance empirical analyses, inform policy decisions, and advance knowledge in econometrics and related disciplines.
On Virasoro-type reductions and inverse Hamiltonian reductions for $W$-algebras and $W_\infty$-algebras

Field: Mathematics (Physical Sciences)

In this article, the Virasoro-type reduction and the corresponding inverse reductions are established for W-algebras associated with classical Lie type and nilpotent orbits of height two. Moreover, these results are lifted to the universal objects by analyzing the Virasoro-type reduction of the vertex algebra $\mathcal{W}^{\mathfrak{sp}}_{\infty}$.
Qsi Dynamical Fetch Policy For Smt

Field: Computer Science (Physical Sciences)

A Simultaneous Multithreading (SMT) Processor is capable of executing instructions from multiple threads in the same cycle. SMT in fact was introduced as a powerful architecture to superscalar to increase the throughput of the processor. Simultaneous Multithreading is a technique that permits multiple instructions from multiple independent applications or threads to compete limited resources each cycle. While the fetch unit has been identified as one of the major bottlenecks of SMT architecture, several fetch schemes were proposed by prior works to enhance the fetching efficiency and overall performance. In this paper, we propose a novel fetch policy called queue situation identifier (QSI) which counts some kind of long latency instructions of each thread each cycle then properly selects which threads to fetch next cycle. Simulation results show that in best case our fetch policy can achieve 30% on speedup and also can reduce the data cache level 1 miss rate.
Tarsal tunnel syndrome in rheumatoid arthritis.

Field: Medicine (Health Sciences)

Recent reports suggest an increased incidence for the general population of tarsal tunnel syndrome (TTS) in rheumatoid arthritis (RA), similar to that previously reported for carpal tunnel syndrome. Proof of this supposition could be important in the diagnosis and management of pain in the feet of patients with RA. Thirty-nine patients with a classical diagnosis of RA by clinical and laboratory criteria had electrodiagnostic studies performed on both posterior tibial nerves and other nerves as indicated. These tests found a 15% incidence of peripheral neuropathy and a 5% incidence of TTS in patients with RA.
An optimization problem in examination technique

Field: Decision Sciences (Social Sciences)

A survey of exam marks reveals a systematic tendency for wider spreads of marks to be awarded in some subjects than others in the same stage of a degree course. Arguably this is a defect that should be corrected, for a student may be able to benefit his overall position in class by diverting effort from small‐spread subjects to concentrate on gaining high placings in wide‐spread subjects. The situation is illustrated by the behaviour of CASSIUS, an imaginary student, who makes the best assumptions he can about the examination system and orders his efforts accordingly. It appears that he can usefully improve his overall rating by redistributing his effort without increasing it. Evidently a new look at subject‐weighting, taking account of marks‐spreads as well as marks‐averages, is desirable
CETP Gene Variation And Cholesterol Response To Resistance Exercise Training In MERET

Field: Medicine (Health Sciences)

PURPOSE Aerobic exercise is known to reduce blood cholesterol though the response is variable between individuals. Moreover, previous studies have produced equivocal results on the blood cholesterol response to resistance training (RET). The Cholesterol Ester Transfer Protein (CETP) gene contains a polymorphism that has been suggested to affect cholesterol metabolism and thereby blood cholesterol levels. METHODS We investigated whether the gene variant was associated to blood cholesterol responses in 91 young (18–30 years) adult men and women who participated in 10 weeks, 3 hrs/week of RET at 80% of one repetition maximum. Fasting blood samples were collected at baseline and at the end of RET. RESULTS At baseline, women (N=47) had significantly higher total (179±6 vs 165±6 mg/dl), and HDL cholesterol (54±10 vs 43±6), and lower Chol:HDL (3.4± vs 3.8±) than men (N=44). CETP genotype was significantly (P<0.05) associated to change in total (AA=−0.3±3.6, N=27, AG=−1.4±2.7, N=48, GG=13.5±4.8, N=15), HDL (AA=0.3± 1.1, AG=−0.5±.8, GG=3.4±1.5) and LDL (AA=1.4± 3.4, AG=−2.1±2.5, GG= 15.0±4.6) cholesterol. There were no significant interactions with gender. CONCLUSIONS These results suggest that the CETP genotype is associated with blood cholesterol response to RET.
Estrogen Receptor-α (ERα) Expression in Lymphocyte Subsets of Parous and Nulliparous Women with Multiple Sclerosis (I5.012)

Field: Medicine (Health Sciences)

Objective: To evaluate the frequency of Th1, Th2, Th17, Treg and NK CD56bright cells and their Estrogen Receptor alpha (ER-α) expression in nulliparous and parous patients with Multiple Sclerosis (MS). Background: During the last trimester of pregnancy women with MS experience an increase in estrogen (E) associated with a significant decrease in relapse rate. In addition, pregnancy seems to ameliorate the short-term course of MS in terms of relapse rate and progression to irreversible disability. Factors involved in this process are still unknown, but hormone-dependent immunological tolerance mechanisms and neuroprotection may play a crucial role. Methods: Peripheral blood mononuclear cells (PBMC) have been collected from 20 nulliparous and 20 parous MS patients. Frequencies of Th1, Th2 and Th17 cells have been assessed after short (4-6 hours) re-stimulation with PMA and ionomycin, while Treg and NK CD56bright have not been stimulated. Each sample has been stained also with anti-ER-α antibody and then flow cytometric analysis has been performed. Results: Both nulliparous and parous MS patients show unaltered frequencies of Th2, Treg and NK CD56bright cells. Parous MS patients have significantly lower Th1 and Th17 frequencies than nulliparous patients. In addition, parous MS women have a smaller proportion of ER-α+ NK CD56bright and ER-α+ Th1 cells, although these latter have a higher mean fluorescence intensity (MFI) compared with those of nulliparous women. Conclusions: The finding of a lower frequency of pro-inflammatory T cell subsets, Th1 and Th17, in parous MS patients after pregnancy suggests that this phenomenon may be responsible for a milder disease activity. In addition, a higher ER-α expression in Th1 and NK CD56bright cells in women with previous pregnancies, may modulate the levels of circulating pro-inflammatory subsets in these patients.
Protein Sequencing Research Group (PSRG): Results of the PSRG 2012 Study Year 1: Terminal Sequencing of Fusion Proteins

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Establishing the N-terminal sequence of intact proteins plays a critical role in biochemistry and drug development. N-terminal sequence analysis is necessary for quality control of protein biologics, for determining sites of signal peptide cleavage events, for characterizing monoclonal antibodies, and in elucidating sequences of genes from uncommon species. N-terminal sequencing is in the midst of a technology transition from classical Edman sequencing to mass spectrometry (MS) based terminal sequencing. Protein homogeneity (absence of interfering protein, non-protein contaminants and buffer components) is absolutely critical to the success of analysis. While it has been very straightforward to isolate the protein of interest out of protein mixtures in preparation for Edman sequencing, core facilities now need to adopt novel sample preparation techniques to isolate proteins in high purity and make them amenable for terminal sequencing by MS. There is a lack in easy-to-use, field proven methods for sample clean-up. In order to address the upcoming change in technology platforms, the PSRG is conducting a two-year study with the ultimate goal of sample preparation and terminal sequencing of a protein mixture. The 2012 study is the first phase towards the overall goal and entails terminal sequencing and identification of fusion proteins, which were provided as separated, homogeneous proteins. Participants used Edman and/or MS techniques, along with bioinformatics tools to derive the termini of the sample proteins. Study participants were directed to a website to anonymously upload sequences and supporting data. Our analysis focused on critical comparison of results obtained by different technology platforms. The results obtained by Edman sequencing and MS as well as information on the type of instruments and protocols will be presented. This data and information will be provided to the community in conjunction with year two of the study, which will be the same proteins supplied in mixture.
Merging diaries and GPS records: The method of data collection for spatio-temporal research

Field: Social Sciences (Social Sciences)

Abstract The results of a ‘proof-of-concept’ study that examined a new opportunity for using GPS technology in activity surveys are presented in this article. The aim is to demonstrate the method of collection and processing of individual time-space data via the dual records of a time-space diary and the GPS locator. The GPS technology here is not treated as a substitute for the traditional method of diaries; rather, the paper concentrates on the potential existing in a combination of these two techniques. The time-geographical approach and the corresponding methodology are used in order to assess the complexities of an individual’s everyday life, and to capture the spectrum of human activities in a data frame applicable to different analyses in behavioural, social and transportation research. This method not only improves the quality and robustness of spatio-temporal data, but also reduces under-reporting and the burdens on the respondents.
THE NATIONAL COORDINATION OF EU POLICY IN HUNGARY: PATTERNS OF CONTINUITY AND CHANGE

Field: Social Sciences (Social Sciences)

Although European Union (EU) membership generates similar functional pressures for national administrations, member states developed institutional arrangements that show marked cross‐country variation in the coordination of EU policy. This article examines and assesses the institutions and mechanisms established in Hungary for formulating policy positions on the domestic level. In line with the general features of central government, the system is highly centralized and hierarchical, and has been characterized by a comprehensive coordination ambition from its inception. The case confirms the primary importance of national institutional factors for shaping coordination systems, but also the relevance of more actor‐centered explanations for accounting for changes in the top decision‐making tier. At the same time, the Hungarian experience also draws attention to power relations within governing parties and prime ministerial involvement as important variables so far relatively neglected in the literature.
NON-NEWTONIAN EFFECTS ON FLOW GENERATED CAVITATION AND ON CAVITATION IN A PRESSURE FIELD

Field: Chemistry (Physical Sciences)

Observations are presented which show that the stresses in a flow field of a very dilute polymer are not well enough described by the Navier-Stokes equations to accurately predict cavitation. The constitutive equation for the particular polymer and concentration used is needed. The second-order fluid form in which accelerations are relatively important appears capable of explaining observed cavitation suppression by changing the pressure field due to flow. Bubble dynamics in stationary dilute polymer solutions are also examined and found to be little different from those in water. (Author)
Megaprosthesis of the knee in tumor and revision surgery.

Field: Medicine (Health Sciences)

The introduction of multidisciplinary approach with chemo and radiotherapy, the advances in surgical and the improvements of diagnostic techniques allowed limb salvage surgery in most cases of bone sarcomas instead of amputation. Modular megaprostheses are the most common method of reconstruction after segmental resection of the long bones in the extremities for their availability, immediate fixation, early weight bearing, good function. Despite the advances in materials and implant designs, these systems have an high incidence of complications. Aim of this study was to report the experience on mega-prostheses implanted around the knee in tumor and revision surgery to analyze: the most frequent used current systems, the problems of stems fixation, extensor mechanism reconstructions in proximal tibia resections and the preservation of growth of the lower extremity in children.
Generating Multi-Agent Trajectories using Programmatic Weak Supervision

Field: Computer Science (Physical Sciences)

We study the problem of training sequential generative models for capturing coordinated multi-agent trajectory behavior, such as offensive basketball gameplay. When modeling such settings, it is often beneficial to design hierarchical models that can capture long-term coordination using intermediate variables. Furthermore, these intermediate variables should capture interesting high-level behavioral semantics in an interpretable and manipulatable way. We present a hierarchical framework that can effectively learn such sequential generative models. Our approach is inspired by recent work on leveraging programmatically produced weak labels, which we extend to the spatiotemporal regime. In addition to synthetic settings, we show how to instantiate our framework to effectively model complex interactions between basketball players and generate realistic multi-agent trajectories of basketball gameplay over long time periods. We validate our approach using both quantitative and qualitative evaluations, including a user study comparison conducted with professional sports analysts.
Use of Nutraceuticals in Elderly to Fight Inflammation and Immuno-Senescence: A Randomized Case-Control Study

Field: Medicine (Health Sciences)

Elderly people are at high risk of suffering from infection and being affected by severe forms of disease because their immunosystem suffers from aging. The alteration of normal immune functions causes the increase of pro-inflammatory cytokines which can expose these people to increased risk of developing pathologies as cancer, diabetes, and/or arthritis. Some supplements could be helpful for restoring normal immune functions. We conducted a case-control study to evaluate the efficacy of a supplement containing Sambucus nigra, zinc, tyndallized Lactobacillus acidophilus (HA122), arabinogalactans, vitamin D, vitamin E, and vitamin C to improve the inflammatory levels (IL-6 and CRP) and to modulate the lymphocytes growth. Additionally, we analyzed wellness by self-questionnaire. This study had two control group: a young group and an elderly one. Our study showed that treating elderly patients with the supplement for 30 days improved IL-6, CRP, and lymphocytes levels; the result was independent from the dosage of the supplements used. Elderly patients, despite the improvement, were not able to reach the same conditions of young patients; however, most of the patients (>70%) claimed to “feel better” after the use of the supplement. The use of this supplement should be considered at a low dosage for a prolonged period to reduce inflammation and modulate immune senescence in patients over 60 years old.