jimnoneill/paper-to-field-training huggingface dataset:
Abstract TP229: Measurement of Multiple Blood Markers to Predict Long- term Outcome in Ischemic Stroke

Field: Medicine (Health Sciences)

Background and Purpose: There is no single blood marker for prediction of prognosis in ischemic stroke. We investigated whether multiple blood markers enhance the predictability of long-term outcome following ischemic stroke. Methods: Blood concentrations of neuronal markers (NSE, VSNL-1, H-FABP, and Ngb), astroglial markers (S100B and GFAP), inflammatory markers (IL-6, TNF-α, WBC count, and CRP), blood-brain barrier marker (MMP-9), and haemostatic markers (D-dimer and PAI-1) were compared with favorable and poor outcome groups regard to 3 month clinical outcome. Multivariate logistic regression analysis, area under receiver operator characteristic (AUROC) curve, and net reclassification improvement (RNI) index were performed to examine whether adding blood markers to baseline clinical model (age, sex, initial NIHSS score, and atrial fibrillation) improves discrimination for poor and good outcome. Results: In multivariate analysis, plasma IL-6 (OR, 1.013, per 10 pg/ml, 95% CI, 1.04 - 1.23, P = 0.003) was independently associated with poor outcome 3 months after onset, and hFABP (OR, 1.05, per 1 ng/ml, 95% CI, 1.00 - 1.09, P = 0.048), WBC (OR, 1.22, per 103/uL, 95% CI, 1.00 - 1.49, P = 0.046), and S100B (OR, 1.05, per 10 pg/ml, 95% CI, 1.01 - 1.09, P = 0.017) showed a marginal association with poor outcome. Addition of single blood marker to baseline clinical model did not improve discrimination for poor outcome from good outcome. Addition of four blood markers including IL-6, hFABP, WBC, and S100B to baseline clinical model showed improvement of discrimination for poor outcome from good outcome (AUROC: 0.95, NRI index, 0.14, p = 0.02). Conclusions: Combination of neuroglial and inflammatory blood markers including IL-6, hFABP, WBC count, and S100B has an additive predictive value for stroke outcome.
Procedurally Generated Dungeons

Field: Computer Science (Physical Sciences)

For many people, procedurally generated dungeons are one of the main defining characteristics of the roguelike genre, if not the most important one. Because of that, there is a lot of work, lore, and techniques developed in the last decades covering this topic, and it would be impractical for an introductory book such as this one to cover a significant part of the techniques available to roguelike developers. Instead, we're going to focus on one type of dungeon generation that is easy to understand and experiment with while just describing others without implementing them. It is important to understand that even though the algorithm behind the dungeon generation explained in this chapter is easy, it is a battle-tested way of generating dungeons with many games using it.
DIAMAP: a new way of working to develop a future research strategy

Field: Health Professions (Health Sciences)

The epidemic of diabetes and the burden of mortality and morbidity from complications can only be tackled by research. The present investment in research is not sufficient for the exponential rise in the number of people with diabetes across Europe and the rising costs of treatment and care at such a time of economic uncertainty. It is known that the direct and indirect costs of diabetes far outstrip the investment in research in Europe. There are no real data available on how much is actually spent on research, although this information is easier to obtain from European sources (e.g. European Commission) than national sources. There is also no strategic research plan at the European level for diabetes research, although several member states do have such a plan. EURADIA developed the DIAMAP (road map for European diabetes research) project to attempt to address these issues with two large-scale surveys and a multi-national and multi-professional expert task force. DIAMAP is now coming to a close with the publication of a major report and presentations during the FEND and the EASD meetings. The future road map report has undergone a public consultation period and garnered feedback from across Europe. This article recounts the approach taken to the surveys, database development and structuring the research road maps to ensure that the patient was at the centre.
Determining the spatial autocorrelation of dengue vector populations: influences of mosquito sampling method, covariables, and vector control

Field: Environmental Science (Physical Sciences)

We investigated spatial autocorrelation of female Aedes aegypti L. mosquito abundance from BG-Sentinel trap and sticky ovitrap collections in Cairns, north Queensland, Australia. BG-Sentinel trap collections in 2010 show a significant spatial autocorrelation across the study site and over a smaller spatial extent, while sticky ovitrap collections only indicate a non-significant, weak spatial autocorrelation. The BG-Sentinel trap collections were suitable for spatial interpolation using ordinary kriging and cokriging techniques. The uses of Premise Condition Index and potential breeding container data have helped improve our prediction of vector abundance. Semiovariograms and prediction maps indicate that the spatial autocorrelation of mosquito abundance determined by BG-Sentinel traps extends farther compared to sticky ovitrap collections. Based on our data, fewer BG-Sentinel traps are required to represent vector abundance at a series of houses compared to sticky ovitraps. A lack of spatial structure was observed following vector control treatment in the area. This finding has implications for the design and costs of dengue vector surveillance programs.
VIII. The Idea of Jesus' Resurrection as the Beginning of the Eschatological Resurrection

Field: Arts and Humanities (Social Sciences)

The idea that Jesus' resurrection formed the beginning of the eschatological resurrection does not appear elsewhere in Paul's letters. Paul's view that Jesus is the first-born, in the sense that he occupies the leading position in the hierarchy of the new age, has been adopted and worked out in Col. 1: 15. The designation of Jesus as the first-born from the dead is just another way of stating that Jesus is Lord over all, dead and living. He is the one through whom God saves the earth. In brief, Matthew's claim that when Jesus died many bodies of saints were raised and appeared after Jesus' resurrection is unrelated to Paul's idea that Jesus' resurrection formed the beginning of the eschatological resurrection. It is most likely that the idea that Jesus' resurrection was the beginning of the eschatological resurrection, as it is conveyed in 1 Cor. 15:20, is Paul's own invention.Keywords: eschatological resurrection; Jesus' resurrection; Matthew; Paul
Community-based adaptation to climate change in Africa: a typology of information and institutional requirements for promoting uptake of existing adaptation technologies

Field: Environmental Science (Physical Sciences)

The global phenomenon of climate change constitutes major threats to Africa (IPCC, 2007). Although the impact of climate change is global, for various reasons including the state of preparedness of the continent, it has been estimated that Africa will be most vulnerable to climate change (Arnell, 2004 and IPCC, 2007). The impacts of climate change in the continent are manifested in various forms including extreme weather patterns, prolonged droughts, flash floods, decline in crop productivity and loss of livestock due to droughts, resurgence of malaria in highland areas, water and pasture scarcities leading to conflicts. The challenges in capacity and the availability of resources and the existence of a high dependence on natural resources increase the risks and uncertainties to livelihoods of the rural poor, as the natural resource base becomes more vulnerable to the vagaries of \nclimatic changes (Denton et al., 2000).
PO-0450 Correlation Between Early Cerebral Function Monitoring (cfm) And Csf Neuron-specific Enolase (nse) In Neonates With Hypoxic Ischaemic Encephalopathy (hie): Abstract PO-0450 Table 1

Field: Medicine (Health Sciences)

<sec><st>Background and aims</st> aEEG predicts outcome in newborns with HIE. CSF-NSE serves as surrogate for HI brain injury. Little is known about the correlation between early aEEG and CSF-NSE within the first 72 h of age. </sec> <sec><st>Aim</st> To examine the correlation between early aEEG and CSF -NSE concentrations in neonates with HIE. </sec> <sec><st>Methods</st> Prospective observational study of term infants with HIE admitted at Agrupació Sanitaria Sant Joan de Déu-Clinic from 2009 through 2011. HIE was clinically graded according to a validated system. Patients with significant HIE underwent therapeutic hypothermia. CFM was performed in all cases. Pattern classification was ranked from 1 to 5 (with higher scores indicating more suppressed traces). The worst CFM tracing within the first 6 h and 6 to 12 h was correlated with CSF NSE performed at 12 h and 72 h. </sec> <sec><st>Results</st> Clinical characteristics of patients are summarised in the <cross-ref type="tbl" refid="T1">Table 1</cross-ref>. <tbl id="T1" loc="float"><no>Abstract PO-0450 Table 1</no><caption> Clinical characteristics of patients </caption><tblbdy><r><c cspan="1" rspan="1"> </c><c cspan="1" rspan="1"> <b>Total HIE N=55</b> </c><c cspan="1" rspan="1"> <b>Mild HIE</b> <br> <b>(N=12) 21.8%</b> </c><c cspan="1" rspan="1"> <b>Moderate HIE</b> <br> <b>(N=15) 27.3%</b> </c><c cspan="1" rspan="1"> <b>Severe HIE</b> <br> <b>(N=28) 50.9%</b> </c></r><r><c cspan="1" rspan="1">Outborn%</c><c cspan="1" rspan="1">66.1%</c><c cspan="1" rspan="1">16.7%</c><c cspan="1" rspan="1">73.3%</c><c cspan="1" rspan="1">85.7%</c></r><r><c cspan="1" rspan="1">Weight (g), mean (SD)</c><c cspan="1" rspan="1">3035(580)</c><c cspan="1" rspan="1">3056(505)</c><c cspan="1" rspan="1">3075(554)</c><c cspan="1" rspan="1">2994(584)</c></r><r><c cspan="1" rspan="1">Death</c><c cspan="1" rspan="1">33.9%</c><c cspan="1" rspan="1">0%</c><c cspan="1" rspan="1">6.7%</c><c cspan="1" rspan="1">64.3%</c></r></tblbdy></tbl> The degree of neonatal encephalopathy was related with CSF-NSE concentrations at 12 (r<inf>s </inf>= 0.38) but overall at 72 h of life (r<inf>s </inf>= 0.83). aEEG traces at 6 h but also at 6–12 h were correlated with CSF-NSE concentration at 12 h (r<inf>s </inf>= 0.544 and r<inf>s</inf>= 0.529) and even more significant at 72 h (r<inf>s</inf> = 0.790 and r<inf>s </inf>= 0.768, respectively). </sec> <sec><st>Conclusions</st> Our study provides additional support about aEEG monitoring during the first 12 h is a reliable biomarker for early estimates of ongoing brain damage in neonatal HIE. </sec>
Strategi Local-Sosiosaintific Issues Dengan OE3C Instructional Terhadap Kemampuan Literasi Sains Siswa Di Sekolah Dasar

Field: Social Sciences (Social Sciences)

Multiple pedagogical research have shown that guided inquiry-based learning increases students' scientific literacy. The Program for International Student Assessment (PISA) conducted a study of scientific literacy between 2000 and 2015, and their findings show that students in Indonesia still have a low level of scientific literacy compared to other OECD (Organization for Economic Co-operation and Development) countries. flat. Organization for Economic Co-operation and Development) countries. Thus, we set out to investigate whether or whether introducing the Local Socioscientific Issues (SSI) approach from the OE3C Instructional affected students' scientific literacy. A non-blinded pre-post experimental design was adopted for this study's quasi-quantitative method. Correlations between Local Socioscientific Issues (SSI) and OE3C Instructional methods and cyan enhancement. literacy were found in an analysis of obtained data using SPSS Version 26. Consequently, OE3C Instructional may be used to include the Local Socioscientific Issues (SSI) method into elementary school science instruction with the goal of improving students' scientific literacy.
Comparison of changes in pre-induction cervical factors' scores following ripening with transcervical foley catheter and intravaginal misoprostol.

Field: Medicine (Health Sciences)

The study compares the changes in the cervical factors in pre-induction cervical ripening with both transcervical Foley catheter and Intravaginal Misoprostol. This was a randomised prospective study of pregnant women, with singleton gestations who presented for antenatal care and delivery at a tertiary health institution in the South-western Nigeria between 1st March 2003 and 31st March 2004. One hundred and two (102) patients received 50microg intravaginal Misoprostol and Ninety-six (96) received size 16F Transcervical Foley catheters. Both groups were similar at the baseline. Misoprostol group showed greater improvement in the final cervical length score, with 38.4% and 58.6% scoring 2 and 3 respectively, in contrast with the Foley catheter group where 77.7% had final score of 1, with only 16% scoring 2 and none scored 3 (P = 0.00). Ninety-one percent of the patients in the misoprostol group achieved the maximum cervical consistency score of 2, contrasting with the 31.9% in the Foley Catheter group (P = 0.00). 64.9% of the patients in the Foley catheter group did not achieve appreciable change in cervical consistency. Our findings indicate that intravaginal misoprostol was more effective in improving the scores of cervical length and consistency, while transcervical Foley catheter was better at improving the cervical os dilatation score at pre-induction cervical ripening. The clinical implication is that, patients for pre-induction cervical ripening can be selected for either of these ripening agents based on which cervical factors require improvement in scores
Ab Initio Molecular Dynamics Simulations of the Interaction between Organic Phosphates and Goethite

Field: Chemistry (Physical Sciences)

Today’s fertilizers rely heavily on mining phosphorus (P) rocks. These rocks are known to become exhausted in near future, and therefore effective P use is crucial to avoid food shortage. A substantial amount of P from fertilizers gets adsorbed onto soil minerals to become unavailable to plants. Understanding P interaction with these minerals would help efforts that improve P efficiency. To this end, we performed a molecular level analysis of the interaction of common organic P compounds (glycerolphosphate (GP) and inositol hexaphosphate (IHP)) with the abundant soil mineral (goethite) in presence of water. Molecular dynamics simulations are performed for goethite–IHP/GP–water complexes using the multiscale quantum mechanics/molecular mechanics method. Results show that GP forms monodentate (M) and bidentate mononuclear (B) motifs with B being more stable than M. IHP interacts through multiple phosphate groups with the 3M motif being most stable. The order of goethite–IHP/GP interaction energies is GP M < GP B < IHP M < IHP 3M. Water is important in these interactions as multiple proton transfers occur and hydrogen bonds are formed between goethite–IHP/GP complexes and water. We also present theoretically calculated infrared spectra which match reasonably well with frequencies reported in literature.
Interaction between water and nutrient deficiencies in helianthus annuus

Field: Agricultural and Biological Sciences (Life Sciences)

The physiological response of plants to water deficits are known to vary according to the conditions of application of drought stress and the rate of development of leaf water deficits. At the whole plant level the effect of the water shess is usually perceived as a decrease in photosynthesis and growth, and is associated with alterations in C and N metabolism (McDonald and Davies, 1996). The decrease in water potential affects transpiration and hence xylem transport of nitrate or reduced N into growing regions. The response of the photo-synthetic apparatus either to water stress or rehydration seems to be dependent "on leaf age (O'Neill, 1983; Wolfe et al., 1988). Degradation of both thylakoid and stromal N-containing compounds can occur in response to water stress, recovery from which may pequire more than a week (Chaves, 1991).
Towards a Philosophy of Queer Alterity. Faith and Democracy

Field: Arts and Humanities (Social Sciences)

The text is an intervention in post-secularist and anti-fundamentalist philosophy of affective alterity. It attempts to reconstruct the philosophical tradition of affective alterity and to construct a theory of it. Homosexuality is affective alterity, the other love of Thou and I. We explore dynamic religions in their openness to the Other. Emphasis is on Judaism and the "Love the stranger" postulate in the Hebrew Bible; we go back to biblical and rabbinical literature as well as Erich Fromm's and Julia Kristeva's psychoanalytic interpretations of them. The idea of hospitality, rooted in the Bible and the Koran, was revived by Jacques Derrida, Julia Kristeva, Griselda Pollock, and Geoffrey H. Hartman. It is of urgent importance in Poland where fundamentalist misogyny and homophobia increase. In our paper, queer rights are examined as human rights - and this is again pertinent in Eastern Europe. The methodology of the intersection of cultural analysis and Jewish studies here are inspired by Mieke Bal and Ernst van Alphen. The particular connection between Jewishness and queerness is stressed by Daniel Boyarin, Ann Pellegrini and Alisa Solomon; as we write, it is to be found in today's Poland in the Shterndlech Iton Babel magazine, published by the younger generation. Also, the feminist studies of Maria Janion, Kazimiera Szczuka and Bozena Uminska are of significance here. We end with visual culture productions: the queer or omni-sexual art exhibition against nationalist censorship Love and Democracy, curated by Pawel Leszkowicz in Poznan (2005), and in Gdansk (2006). Throughout the paper we propose our understanding of love. The text whose part is entitled "Faith and Democracy" is a sequel to our Polish-language book Love and Democracy. Reflexions on the Homosexual Question in Poland (2005) with an extensive English summary. Our loves, our subjectivities are despised and disrespected, but created in art, philosophical research, and activism. Let us exercise (in) love.
Advances in understanding of mechanisms related to increased cardiovascular risk in COPD

Field: Medicine (Health Sciences)

COPD patients often remain asymptomatic of CVD, with respiratory symptoms generally attributed to the preexisting pulmonary disease. It is fundamental to understand the mechanistic pathways that underpin the intimate relationship between the two disorders. However, it is still not clear what is the origin of the common background of low-grade systemic inflammation, it could be a 'spillover' or a general inflammatory state. Primary prevention, cross-collaboration between specialists and early detection via predictive biomarkers and validated models are fundamental to stratify COPD patients according to CV risk.
The role of action research in the development of socio-emotional skills in students

Field: Social Sciences (Social Sciences)

The paper presents socio-emotional skills in more detail, both through theoretical determination and through practical application in the form of action research with students in the third and fourth grade of primary school. The main goal of the research is to see how emotionally and socially literate students are, how much they know and how much they have developed certain characteristics (more specifically teamwork and creativity). By applying activities that were based on the previously mentioned characteristics, the emphasis was placed on encouraging a warm and pleasant climate in the classroom. The research took place in three phases. The first phase was followed by the design and preparation of both activities and actors. The second phase involved the implementation of activities after each formative evaluation. The third phase involved the final verification of the effects of activities on students, i.e. a summative evaluation, where the opinions of the participants on the work method and the introduced novelties that they had the opportunity to discover were examined. The obtained research results showed positive effects, that the students adopted the necessary and desirable skills in a different and more interesting way, as well as that they liked such applied work.
Sarcina ventriculi synthesizes very long chain dicarboxylic acids in response to different forms of environmental stress.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Changes in the composition of membrane lipids in a strictly anaerobic, facultative acidophilic eubacterium, Sarcina ventriculi, were studied in response to various forms of environmental stress. Changes in lipid composition and structure occurred in response to changes in environmental pH. At neutral pH, the predominant membrane fatty acids ranged in chain length from C14 to C18. However, when cells were grown at pH 3.0, a family of unique very long chain fatty acids containing 32-36 carbon atoms was synthesized and accounted for 50% of the total membrane fatty acids. These acids were identified as very long chain alpha,omega-dicarboxylic acids ranging in length from 28 to 36 carbons by electron impact mass spectrometry of methyl and (perdeuterio) methyl ester derivatives. These methyl esters all bore a vicinal dimethyl group toward the center of the chain. The assignment of the structures was confirmed by isolating one of the very long chain unusual fatty acids as the ester form after methanolysis and performing further analyses including 1H and 13C NMR spectroscopy and Fourier transform infrared spectroscopy. Coupling this information with the data from gas chromatography/mass spectrometry analysis, the exact structure was confirmed as alpha,omega-15,16-dimethyltricotanedioate dimethyl ester. Addition of alcohols, either metabolic (0.25 M ethanol) or nonmetabolic (0.05 M butanol) to cells grown at pH 7.0, or thermal stress (growth temperature at pH 7.0 was raised from 37 to 45 or 55 degrees C) also resulted in the synthesis of these very long chain fatty acids. Synthesis of these very long chain alpha,omega-dicarboxylic acids was reversed by reducing the temperature back to 37 degrees C. S. ventriculi is also unusual in that the membrane components are not the usual phospholipid components but appear to be predominantly glycolipids.
Orientation-weighted local Minkowski functionals in 3D for quantitative assessment of trabecular bone structure in the hip

Field: Medicine (Health Sciences)

Fragility fractures or pathologic fractures of the hip, i.e. fractures with no apparent trauma, represent the worst complication in osteoporosis with a mortality close to 25% during the first post-traumatic year. Over 90% of hip fractures result from falls from standing height. A substantial number of femoral fractures are initiated in the femoral neck or the trochanteric regions which contain an internal architecture of trabeculae that are functionally highly specialized to withstand the complex pattern of external and internal forces associated with human gait. Prediction of the mechanical strength of bone tissue can be achieved by dedicated texture analysis of data obtained by high resolution imaging modalities, e.g. computed tomography (CT) or magnetic resonance tomography (MRI). Since in the case of the proximal femur, the connectivity, regional distribution and - most of all - the preferred orientation of individual trabeculae change considerably within narrow spatial limits, it seems most reasonable to evaluate the femoral bone structure on an orientation-weighted, local scale. In past studies, we could demonstrate the advantages of topological analysis of bone structure using the Minkowski Functionals in 3D on a global and on a local scale. The current study was designed to test the hypothesis that the prediction of the mechanical competence of the proximal femur by a new algorithm considering orientational changes of topological properties in the trabecular architecture is feasible and better suited than conventional methods based on the measurement of the mineral density of bone tissue (BMD).