jimnoneill/paper-to-field-training huggingface dataset:
PHASOR ANALYSIS OF DECENTRALIZED GRID-CONNECTED RESIDENTIAL SOLAR FARM: ADDRESSING NIGERIA ELECTRICITY CAPACITY ISSUES

Field: Energy (Physical Sciences)

Addressing Nigeria’s energy capacity issues, this paper presents a Phasor-evaluation of a simulation comparing the feasibility of using a Photovoltaic (PV) system with backup power for home use at a large-scale solar farm with a Residential Energy Storage System (RESS) in Nigeria. The Hydro-Québec Research Institute (IREQ) designed a standard power operation system for the simulation, which is essential. The findings, displayed in phasor mode, aim to assess energy storage and solar intensity, potentially revolutionizing the energy landscape for Nigeria’s rural and urban residents.
Obsolescence as a pattern: an analysis of how public service media managers perceive and cope with resistance to change in the platformisation era

Field: Social Sciences (Social Sciences)

[Abstract] Platformisation has greatly affected the operations of the media industry, forcing \nmedia corporations to undergo major changes. Under such circumstances, public \nservice media (PSM) corporations have found themselves engaged in a process of \nrethinking their economics, structures and ways of working. However, the latter \nis rarely established without resistance. Through 60 in-depth interviews with \nSpanish PSM managers, this study analyses how resistance to change operates in \nthe ongoing platformisation process. The results confirm the existence of a \nproblem of obsolescence in Spanish PSM, which is motivated by four elements: \nlegislation, financial means, technological capacity, and workforce. Furthermore, \nthree possible strategies to address this challenge are identified: communication, \ntraining, and renewal of professional profiles.
Vanilla (Vanilla planifolia andrews) crop systems used in the Totonacapan area of Veracruz, Mexico: Biological and productivity evaluation

Field: Agricultural and Biological Sciences (Life Sciences)

The genus Vanilla (Orchidaceae) includes around 100 species distributed in the tropics, but only three of them are cultivated commercially, although one of the most used is Vanilla planifolia Andrews. In this study we evaluated the three current vanilla production techniques carried out in area of The Totonacapan, Mexico. During two years (1999 and 2000) environmental characteristics (soil moisture and pH, environmental humidity and temperature and canopy covering) were determined. We found a relationship between these factors with the survival of the fruits (as a production parameter). The fruit survival was different in the studied orchards in both years. The temperature showed a significant correlation, as well as the relative humidity of the atmosphere. The cultivation system and the handling used in semi-technician parcels (St) allowed to obtain a great number of fruits per infructescence, fruits were of a high size and weight and had a high survival rate. Our investigation showed that the water and its maintenance in the cultivation in form of environmental relative humidity play an important role for the good development of the fruits.
On the Relationship Between Compressive Sensing and Random Sensor Arrays

Field: Computer Science (Physical Sciences)

Random sensor arrays are examined from a compressive-sensing (CS) perspective. It is demonstrated that the natural random-array projections manifested by the media Green's function are consistent with the projection-type measurements associated with compressive sensing. This linkage allows the use of existing compressive-sensing theory to quantify the performance of random arrays, of interest for array design. The analysis demonstrates that the compressive-sensing theory is applicable to arrays in vacuum as well as in the presence of surrounding media; further, the presence of surrounding media with known properties may be used to improve array performance.
Computer-Generated Abstract Paintings Oriented by the Color Composition of Images

Field: Computer Science (Physical Sciences)

Designers and artists often require reference images at authoring time. The emergence of computer technology has provided new conditions and possibilities for artistic creation and research. It has also expanded the forms of artistic expression and attracted many artists, designers and computer experts to explore different artistic directions and collaborate with one another. In this paper, we present an efficient k-means-based method to segment the colors of an original picture to analyze the composition ratio of the color information and calculate individual color areas that are associated with their sizes. This information is transformed into regular geometries to reconstruct the colors of the picture to generate abstract images. Furthermore, we designed an application system using the proposed method and generated many works; some artists and designers have used it as an auxiliary tool for art and design creation. The experimental results of datasets demonstrate the effectiveness of our method and can give us inspiration for our work.
Abstract B109: The role of SIRT6 in drug resistance and cellular senescence in cancer.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Introduction: The Sirtuin family consists of 7 members. They comprize highly conserved NAD+-dependent deacetylases that play an important role in a board spectrum of cellular processes, including metabolism, differentiation, survival and cellular senescence. It has also been suggested that these proteins are central to cancer development and drug resistance. Recent studies have documented that SIRT6, a nuclear chromatin-associated protein, has a key role in genomic stability and degenerative pathologies associated with ageing. Moreover, SIRT6 has been reported to have a function in the regulation of DNA damage repair. Therefore, this research aims to investigate the role of SIRT6 in drug resistance and cellular senescence in cancer cells. Methods: Cell lines that we have used in this research consist of sensitive and resistant breast cancer cells, Hela cells and mouse embryonic fibroblasts (MEFs). To investigate the role of SIRT6 in drug resistance, we treated cells with either epirubicin or paclitaxel, then performed immunofluorescent, comet and repair assays to investigate DNA damage repair. Clonogenic and beta-galactosidase assays were also used to investigate long-term survival and cellular senescence. Results: We found that SIRT6 is elevated in drug resistant cells compared to drug sensitive parental cells and that SIRT6 mediates drug resistance by increasing DNA damage repair. Sirt6-/- MEFs have lower levels of γH2AX accumulation compared to WT MEFs. These higher levels of SIRT6 are also associated with the lower activities of p53 and FOXO3a which are two important cell cycle/survival regulators. Here, we show that depletion of SIRT6 in cancer cells results in a decrease in long-term survival and lower HR and NHEJ DNA repair activity. SIRT6-deficeint cells also exhibit the induction of senescence-associated β-galactosidase activity and flat cell morphology. Conclusion: Our results suggest a novel role of SIRT6 in epirubicin and paclitaxel treatment resistance and cellular senescence. SIRT6 could be a potential biomarker for identifying tumors that are likely to be resistant to these chemotherapeutic agents. It might be also a useful therapeutic target for the prevention of acquired drug resistance and for improving the efficiency of drug treatment. Citation Information: Mol Cancer Ther 2013;12(11 Suppl):B109. Citation Format: Mattaka Khongkow, Eric Lam. The role of SIRT6 in drug resistance and cellular senescence in cancer. [abstract]. In: Proceedings of the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics; 2013 Oct 19-23; Boston, MA. Philadelphia (PA): AACR; Mol Cancer Ther 2013;12(11 Suppl):Abstract nr B109.
Killer Cell Ig-like Receptors (KIR)-Binding Assay for Tumor Cells

Field: Immunology and Microbiology (Life Sciences)

Natural killer (NK) cells play key roles in innate and adaptive immune responses against virus and tumor cells. Their function relies on the dynamic balance between activating and inhibiting signals through receptors that bind ligands expressed on target cells. The absence of inhibitory receptor engagement with their ligands and the presence of activating signals transmitted by activating receptors interacting with specific ligands, leads to NK cell activation (Lanier, 2005; Raulet et al., 2001). Thus, the balance of the ligands expressed for inhibitory and activating receptors determines whether NK cells will become activated to kill the target cells. This protocol allows to assign a precise ligand specificity to any given receptor on NK cells. Thus, if a tumor cell expresses the ligand, this protocol will allow to evaluate its interaction with the specific receptor. In particular, killer cell immunoglobulin (Ig)-like receptors (KIR) recognize their ligands (HLA class I molecules) through the direct contact with HLA class I heavy chain residues and amino acid residues of the bound peptide. This protocol will allow to test the effect of amino acid substitutions or other mutations on the binding of KIR to HLA class I. We used this protocol to depict the role of ERAP1, a key component of the MHC class I antigen processing, in regulating NK cell function by controlling the engagement of inhibitory receptors (Cifaldi et al., 2015).
T-ABAC: An attribute-based access control model for real-time availability in highly dynamic systems

Field: Computer Science (Physical Sciences)

In highly dynamic systems resources may have to be accessed in real-time, within the strict time limits of underlying physical processes, with availability becoming critical. Current access control models such as RBAC and ABAC do not address real-time availability in a scalable way for such scenarios. In this paper we propose a real-time attribute-based access control model that extends the functionality of ABAC by using real-time attributes that reflect the requirements of critical applications. We describe two applications of our model: (a) a substation automation system, and (b) a medical cyber-physical system.
Unveiling the Power of Pedagogically Productive Conversations Among University Teachers

Field: Social Sciences (Social Sciences)

The significance and benefits of discussion in higher education contexts have the potential to improve teaching practices, encourage professional development, and ultimately improve student learning outcomes. This study aims to analyze the potential impact of pedagogically productive conversations among university teachers. The research method uses Systematic Literature Review (SLR). A literature search was conducted through academic databases, such as PubMed, ERIC, and Google Scholar. Through a comprehensive review of relevant literature and firsthand insights from educators, the study delves into the intricacies of pedagogically productive conversations, emphasizing their role in promoting collaboration and creating a supportive academic environment. Furthermore, the paper discusses the challenges and barriers that may impede the implementation of such conversations and proposes strategies to overcome them. Overall, this position paper serves as a valuable resource for educators, administrators, and policymakers, offering insights into the transformative power of pedagogically productive conversations and advocating for their integration into the fabric of university teaching.
TheM/G/1 Queue with Quasi-Restricted Accessibility

Field: Mathematics (Physical Sciences)

We consider single-server queues of the M/G/1 kind with a special kind of partial customer rejection called quasi-restricted accessibility (QRA). Under QRA, the actual service time assigned to an arriving customer depends on his service requirement, say x, the current workload, say w, and a prespecified threshold b. If x + w = b the customer is fully served. If w = b <w + x, the customer receives service time b - w + (w + x - b)f for some random number f ¿ [0, 1], while if w > b the actual service time is the fraction fx of the requirement. The random fractions are assumed to be i.i.d. The main aim of this article is to determine some of the central characteristics of this system in closed form. We derive the steady-state distribution of the workload process, which is also the steady-state distribution of the waiting time, and provide explicit results for the case of service times with rational Laplace transforms, in particular for Erlang or hyperexponential service requirements, and uniformly distributed or constant fractions. We also deal with the case of exponential barriers b (instead of one constant threshold). Furthermore, the distribution functions of the length of a busy period and the cycle maximum of the workload are determined. In the case of phase-type service requirements there is an alternative (martingale) technique to derive the busy period distribution; we illustrate this approach in the case of Erlang(2, ??). Finally, we show in the example of the Erlang(2, ??)/M/1-type QRA queue with deterministic fractions (which is non-Markovian) how to compute the busy period distribution via a duality with a Markovian system.
Recent developments in the construction of metallacycle/metallacage-cored supramolecular polymers via hierarchical self-assembly

Field: Chemistry (Physical Sciences)

This feature article summarized the recent progress on the construction of metallacycle/metallacage-cored supramolecular polymers by the hierarchical self-assembly, and the potential applications in the areas of light emitting, sensing, bio-imaging, delivery and release, etc., are also presented.
Do children favor snacks and dislike vegetables? Exploring children's food preferences using drawing as a projective technique. A cross-cultural study.

Field: Social Sciences (Social Sciences)

Objective: To avoid the rising spread of childhood obesity and preserve resources within planetary boundaries, healthy and sustainable eating habits and the consumption of adequate amounts of fruits and vegetables should be encouraged. Children’s food preference was found to be an important determinant for food choice and consumption. The aim of this study was to explore children’s food preferences using drawing as a projective technique in terms of healthy and sustainable eating and compare food preference patterns in Denmark and Lithuania. Method: In total 484 children, aged between 8 and 13 years old, participated in the study (147 in Denmark and 337 in Lithuania). Participants were asked to fill the food preference questionnaire and answer questions about their daily intake of fruits, vegetables, and snacks and draw their favourite meal afterwards. Sociodemographic questions about children’s age, gender, parents’ employment, and family composition were also included in the questionnaire. Results: Fruits, vegetables, highly processed and animal-based foods were not included in a large part of children’s most preferred meal composition. Favourite meals’ composition varied among children in both countries and included different products from separate food groups. Vegetables were more likely to be present in the children’s favourite meals together with meat products. Girls in both countries had more expressed vegetable preferences than boys. Boys in Lithuania had a relatively more expressed preference for highly processed foods, while Danish girls had a more expressed preference for animal-based products. Conclusions: Children’s preferences for foods such as meat and animal-based products expressed in children’s drawings, might be considered as relatively positive in terms of sustainable eating. However, children’s preferences and intake of fruits and vegetables should still be encouraged among young consumers. Cultural and gender differences in children’s food preferences should be considered while creating interventions and marketing strategies for promoting healthy and sustainable eating among young consumers.
Legal and Ethical Challenges of Genetic Editing Technologies in Professional Sports: An Advanced Statistical Assessment

Field: Social Sciences (Social Sciences)

The rapid advancement of genetic editing technologies, such as CRISPR-Cas9, has introduced unprecedented opportunities and challenges within professional sports. This study aims to systematically evaluate the legal and ethical implications associated with the application of gene editing among elite athletes. Employing a mixed-methods design, we conducted a comprehensive survey of 312 stakeholders-including athletes, coaches, legal experts, and ethicists-across five continents. Advanced statistical analyses, including Structural Equation Modeling (SEM) and Multivariate Logistic Regression, were utilized to identify significant predictors of legal risk perception and ethical concern. Results reveal a pronounced divergence in stakeholder attitudes: while 68% of legal professionals emphasize regulatory gaps, 74% of athletes express uncertainty regarding long-term health consequences. The SEM model demonstrated that perceived fairness (β=0.41, p&lt;0.001) and regulatory clarity (β=0.36, p&lt;0.001) are the strongest predictors of overall acceptance. These findings underscore the urgent need for robust international frameworks to address the multifaceted risks of gene editing in sports and highlight the importance of transparent policy-making. Our research provides actionable insights for regulators, sports organizations, and bioethics committees to anticipate and manage the evolving landscape of genetic technologies in athletics.
Visual desynchronization of cortical EEG impaired by lesions of superior colliculus in rats

Field: Neuroscience (Life Sciences)

It is unclear whether rats with lesions of the superior colliculus (SC) neglect visual stimuli because a) they fail to notice the stimuli or b) they notice the stimuli but fail to make specific orienting movements of the eyes and head toward them. To investigate this issue, we used an index of “noticing” that does not involve overt orienting movements, namely, desynchronization of the cortical electroencephalogram (EEG) in drowsy animals. In the first experiment, large collicular lesions with some invasion of surrounding areas severely impaired EEG desynchronization to a brief overhead flash of light but did not significantly affect desynchronization to brief bursts of white noise. No impairment was found after control lesions of cerebral cortex overlying the superior colliculus or of striate cortex. A subsequent experiment found that the visual impairment was still present when lesions were confined to the superior colliculus. It appears that rats with lesions of the superior colliculus can, in certain circumstances, fail to notice visual stimuli and that in rats, the superior colliculus is concerned not only with specific orienting movements to visual stimuli but also with visual desynchronization of the cortical EEG.
Optical bioluminescence and positron emission tomography imaging of a novel fusion reporter gene in tumor xenografts of living mice.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Noninvasive imaging of reporter gene expression using various imaging modalitiesis playing an increasingly important role in defining molecular events in the field of cancer biology, cell biology, and gene therapy. In this study, a novel reporter vector was constructed encoding a fusion protein comprised of a mutant herpes simplex virus type 1 thymidine kinase (HSV1-sr39tk) (tk), a positron emission tomography (PET) reporter gene, and renilla luciferase (rl), a bioluminescence optical reporter gene joined by a 20 amino acid long spacer sequence. We validated the activity of the two enzymes encoded by the fusion protein (tk(20)rl) in cell culture. Then, tumors stably expressing the tk(20)rl fusion gene were imaged both by microPET and optically using a cooled charge coupled device camera in xenograft-bearing living mice. Using a single fusion reporter (PET/optical) gene should accelerate the validation of reporter gene approaches developed in cell culture for translation into preclinical and clinical models.
Academic Culture in Theological Educational Institutions of the Russian Empire

Field: Arts and Humanities (Social Sciences)

The article is a study of the formation and transformation of academic culture in Orthodox theological educational institutions of the Russian Empire in the eighteenth– early twentieth centuries. The research is based at various ego-sources (correspondence, memories), as well as official documents (legislation of the Russian Empire, charters of educational institutions, business documentation, and above all, journals of meetings of conferences and research councils of spiritual academies). A number of works on the history of spiritual academies, published in the nineteenth – early twentieth centuries, are to be taken for sources of the current study. Academic culture is interpreted as a complicated and wholesome system containing a variety of components. The most important of these components are the symbolic and organizational ones. The symbolic culture of the academic spiritual corporation was shaped under the influence of the symbolic culture that had been formed among the clergy for centuries. It is well-known, that not all teachers at spiritual academies were clergy, but before the reforms of the 1860s, almost all teaching staff came from the clergy. A few cases of inviting Western scholars as teachers do not change the general picture, but, on the contrary, it demonstrates how the corporation got rid of ‘alien elements’ (the incident of I. Fessler, for instance). The specifics of the academic culture dominating in the Orthodox educational institutions of the Russian Empire was largely determined by the fact that, outside the walls of seminaries and academies, the majority of teachers and students belonged to the same subculture of the Orthodox clergy. That subculture was shaped in the eighteenth century; its ultimate formation as a subculture occurred after the legal registration of the status of estates in the Russian Empire during the reign of Empress Catherine the Great. Transformations of academic culture were largely associated with changes in that subculture, which were started in the second half of the nineteenth century. In the last third of the nineteenth century, a reform of the higher spiritual educational institutions took place: graduates and students received an opportunity to undergo internships abroad, which changed the landscape of Russian theological discipline. The result of the estates reforms was the arrival of representatives of other estates into religious spiritual educational institutions, and that also had a powerful influence at the academic culture of those institutions.
Supplementary Table 2 from Somatic <i>ERCC2</i> Mutations Correlate with Cisplatin Sensitivity in Muscle-Invasive Urothelial Carcinoma

Field: Medicine (Health Sciences)

<p>All alterations in responders and non-responders. All somatic mutations and short insertion/deletions are listed, with additional annotations regarding genomic coordinates, protein change, allelic fractions, and validation status (if available).</p>