jimnoneill/paper-to-field-training huggingface dataset:
Thermal Microdebridement Does Not Affect the Time Zero Biomechanical Properties of

Field: Medicine (Health Sciences)

Tendinosis is one of the most common causes for patients to seek medical care from primary care providers, physical therapists, and orthopaedic surgeons. The most commonly affected tendons include the Achilles tendon, rotator cuff, extensor carpi radialis brevis, and the leg extensor mecha-nism (quadriceps and patellar tendons). Unfortunately, tendinosis can be refractory to standard nonoperative treatment modalities, and, occasionally, surgical interven-tion is required.1,3,5,8,9,14,24,33,35,47 Historically, tendinosis was labeled tendinitis and believed to be the result of an inflammatory response affecting the tendons. More recently, histologic findings of affected tendons have characterized the disorder as disor-ganized collagen fibers embedded in mucoid substance with areas of tissue necrosis.3,21,26,35,49 Several authors have theorized that excessive training or overuse of fatigued muscle predisposes tendons to increased tensile loads. Over time, microtears occur in the tendon. These microtears are apparently too small to elicit an inflamma-tory response, or they occur more rapidly than the body’s
CfP: Special Issue of the European Journal of American Culture: "American Horror Story", Deadline: Sept 10, 2017

Field: Arts and Humanities (Social Sciences)

Guest Editors: Harriet Earle, Sheffield Hallam University, UK Jessica Clark, University of Suffolk, UK This call for papers seeks submissions that engage with the television series American Horror Story (produced by Ryan Murphy and Brad Falchuk) as part of a Special Issue for the European Journal of American Culture.
DOI: 10.1016/j.jssc.2009.01.027 1 Metamagnetic transition in the 75 K antiferromagnet Gd4Co2Mg3

Field: Physics and Astronomy (Physical Sciences)

Gd4Co2Mg3 (Nd4Co2Mg3 type; space group P2/m; a = 754.0(4), b = 374.1(1), c = 822.5(3) pm and � = 109.65(4)°) as unit cell parameters) was synthesized from the elements by induction melting in a sealed tantalum tube. Its investigation by electrical resistivity, magnetization and specific heat measurements reveals an antiferromagnetic ordering at TN = 75(1) K. Moreover, this ternary compound presents a metamagnetic transition at low critical magnetic field (Hcr = 0.93(2) T at 6 K) and exhibits a magnetic moment of 6.3(1) µB per Gd-atom at 6 K and H = hal-00372463, version 1- 1 Apr 2009 4.6 T. Due to this transition the compound shows a moderate magnetocaloric effect; at 77 K the maximum of the magnetic entropy change is �SM =-10.3(2) J/kg K for a field change of 0-4.6 T. This effect is compared to that reported previously for compounds exhibiting a magnetic transition in the same temperature range.
Masculinity and School Engagement in Middle School

Field: Psychology (Social Sciences)

abstract: The primary goal of this study was to extend previous research on traditional masculinity by examining the longitudinal associations between traditional masculinity, school engagement and attitudes toward school in a sample of middle school students. Following a sample of 338 (Mage = , SDage = , 54% male, 46% Latino) students from the 7th to 8th grades, I examined how students' self-reported endorsement of and adherence to physical toughness and emotional stoicism norms of masculinity were associated with their engagement with school and their attitudes of school liking and school avoidance. I also examined whether the endorsement and adherence to these norms varied by sex and ethnicity, and whether they changed over the one-year period. Results indicated that endorsing and adhering to masculinity norms of emotional stoicism were negatively associated with school engagement, after controlling for school engagement at Time 1. Furthermore, endorsing and adhering to masculinity norms of physical toughness were negatively associated with attitudes of school liking even when controlling for school liking at Time 1. These results were the same boys and girls, and for Latino and White adolescents. Moreover, results indicated sex, but no ethnicity differences in traditional masculinity, such that males generally reported higher levels of endorsement and adherence to norms of physical toughness and emotional stoicism. There were also identifiable developmental patterns in traditional masculinity over a one-year period. The contributions of these findings to the current scholarship on masculinity, along with their implications for future research and practice, are discussed.
Long‐term variations of the electron slot region and global radiation belt structure

Field: Physics and Astronomy (Physical Sciences)

We report the observations of changes of the nominal position of the quiet‐time radiation belt slot over the solar cycles. It has been found that the slot region, believed to be a result of enhanced precipitation losses of energetic electrons due to their interactions with VLF waves in the magnetosphere, tends to shift to higher L (∼3) during a solar maximum compared to its canonical L value of ∼2.5, which is more typical of a solar minimum. The solar‐cycle migration of the slot can be understood in terms of the solar‐cycle changes in ionospheric densities, which may cause the optimal wave‐particle interaction region during higher solar activity periods to move to higher altitudes and higher latitudes, thus higher L . Our analysis also suggests that the primary regions of wave‐particle interaction processes that result in the slot formation are located off of the magnetic equator.
Reading Recovery: Waves of influence on literacy education

Field: Social Sciences (Social Sciences)

Helping children learn to read and write by reading books and writing stories is based on a quite different theory than teaching children by other schemes, such as learning isolated letters and words. We will examine some fundamental assumptions of Clay’s theory of reading and writing continuous text, such as levels of language, processing behaviors, and a gradient of text difficulty. When literacy learning is based on continuous text rather than systematic and sequential learning of prescribed sets of items different teaching-learning interactions are required. The complexity of these teaching interactions mirror the complex acts of real reading and writing. For example, as a child encounters continuous text, the teacher notices the multiple levels of language that the child is using. Thus, the teacher's next move incorporates information about this child's immediate response to this text. We will discuss the complex relationships that undergird teacher-child interactions by exploring ideas such as instructional conversations, reading and writing as problem solving, the importance of independence and flexibility from the beginning, and the unique nature of individual paths of progress. In a problem-solving model that is based on teaching children, professional development focuses on the expansion of teaching capacity through the development of expertise. Expertise is defined as the ability to solve problems in novel ways rather than developing expertise in the use of routine practices or procedures. Professional development is child-driven in its implementation and evaluation. Critical factors for a solid framework of professional development are the melding of theory and practice, robust initial training followed by continuing support, collegiality and guidance, and accountability for children's progress.
Intergenerational solidarity in times of crisis: new relationships between children and grandparents in Spain

Field: Social Sciences (Social Sciences)

This chapter analyses the intergenerational transfers between grandparents and grandchildren in Spain using data from the Survey of Health, Ageing, and Retirement in Europe 2004–17 and the Dependent Care Survey (2014). The chapter first provides an overview of the basic demographic characteristics of the child population in Spain (0–17 years), its evolution from the early years of the demographic transition as well as the projections for the next 20 years. Second, it examines the material contribution of grandparents to the well-being of their grandchildren, both in the form of care and as economic resources. The results show that the intensity of care among grandparents is much more intense in Spain than in other European countries. Likewise, care arrangements generate a type of special relationship between children and other family members, where grandchildren play the role of 'mediators' between the other two generations.
Genetic Approach to Minimizing Energy Consumption of VLSI Processors Using Multiple Supply Voltages

Field: Computer Science (Physical Sciences)

This paper presents an efficient search method for a scheduling and module selection problem using multiple supply voltages so as to minimize dynamic energy consumption under time and area constraints. The proposed algorithm is based on a genetic algorithm so that it can find near-optimal solutions in a short time for large-size problems, n efficient search can be achieved by crossover that prevents generating nonvalid individuals and a local search is also utilized in the algorithm. Experimental results for large-size problems with 1,000 operations demonstrate that the proposed method can achieve significant energy reduction up to 50 percent and can find a near-optimal solution (within 2.8 percent from the lower bound of optimal solutions) in 10 minutes. On the other hand, the ILP-based method cannot find any feasible solution in one hour for the large-size problem, even if a state-of-art mathematical programming solver is used.
Formal Models and International Studies

Field: Social Sciences (Social Sciences)

This article discusses the application of formal models in International Relations,and argues that international studies can benefit from using formal models,this embodies the following aspects: Through clarification of theoretical assumptions,formal models help researchers get a better understanding of the application sphere of theoretical conclusions.They can also help researchers make clear and reliable analysis upon the related mechanisms.Accumulation of knowledge can be achieved through series of models.Repetition in the processing of reasoning can be avoid largely through the application of formal models.This article also discusses the application of formal models in International Relations through a developing direction of rational choice,collective choice and game theory.
Forensic Analysis of Heterogeneous Social Media Data

Field: Computer Science (Physical Sciences)

It is a challenge to aggregate and analyze data from heterogeneous social media sources not only for businesses and organizations but also for Law Enforcement Agencies. The latter’s core objectives are to monitor criminal and terrorist related activities and to identify the ”key players” in various networks. In this paper, a framework for homogenizing and exploiting data from multiple sources is presented. Moreover, as part of the framework, an ontology that reflects today’s social media perceptions is introduced. Data from multiple sources is transformed into a labeled property graph and stored in a graph database in a homogenized way based on the proposed ontology. The result is a cross-source analysis system where end-users can explore different scenarios and draw conclusions through a library of predefined query placeholders that focus on forensic investigation. The framework is evaluated on the Stormfront dataset, a radical right, web community. Finally, the benefits of applying the proposed framework to discover and visualize the relationships between the Stormfront profiles are presented.
Infrared imaging spectroscopy of skin cancer lesions

Field: Medicine (Health Sciences)

Skin cancer is a disease of the twenty-first century since, unfortunately, being tan is associated to be healthy and good looking. UV radiation produces one of the most aggressive kinds of skin cancer: melanoma; once the damage is done there is no other solution that a rapid and effective diagnosis. Clinical examination and biopsies have shown to be slow and costly in many ways, so the possibility of getting a non-invasive optical detection of skin melanomas became a hot topic in biophotonics. In this context, multispectral imaging systems have approached the problem, but none of them worked inside the infrared range. Hence, this work has been proposed as an interesting, long-term project to further investigate about the possibilities of infrared imaging spectroscopy for the early detection of skin cancer through the development of such a system based on an InGaAs camera.
Data from Antitumor Effects of Blocking Protein Neddylation in T315I-BCR-ABL Leukemia Cells and Leukemia Stem Cells

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

<div>Abstract<p>Imatinib revolutionized the treatment of chronic myeloid leukemia (CML), but drug resistance and disease recurrence remain a challenge. In this study, we suggest a novel strategy based on blocking protein neddylation to address BCR-ABL point mutations and leukemia stem cells (LSC) that lie at the root of imatinib-resistant recurrences. On the basis of the finding that the NEDD8-activating enzyme subunit NAE1 is overexpressed in CML cells, we hypothesized that the function of certain neddylation-dependent protein substrates might be targeted to therapeutic ends in imatinib-resistant CML cells and LSCs. In support of this hypothesis, we demonstrated that the NAE1 inhibitor MLN4924 induced G<sub>2</sub>–M-phase arrest and apoptosis in bulk CML cells with wild-type p53, regardless of their T315I mutation status in BCR-ABL. Moreover, MLN4924 inhibited the survival and self-renewal of primary human CML CD34<sup>+</sup> cells and LSCs in CML-bearing mice via accumulation of p27<sup>kip1</sup> in the nucleus. Notably, <i>p27<sup>kip1</sup></i> silencing attenuated the suppressive effect of MLN4924 on the maintenance of LSCs in CML-bearing mice. Taken together, our findings offer a preclinical proof of concept for targeting protein neddylation as a novel therapeutic strategy to override mutational and LSC-derived imatinib resistance in CML.</p><p><b>Significance:</b> These findings highlight a mediator of protein neddylation, a type of protein turnover mechanism, as a viable therapeutic target against imatinib-resistant forms of chronic myelogenous leukemia. <i>Cancer Res; 78(6); 1522–36. ©2018 AACR</i>.</p></div>
A role of mTOR in cigarette smoke-induced corticosteroid insensitivity

Field: Medicine (Health Sciences)

Introduction The corticosteroid insensitivity is a major barrier to the treatment of severe asthma and COPD. It has been revealed that cigarette smoke induced inactivation of HDAC2 through activation of PI3K/Akt pathway, leading to corticosteroid insensitivity. Mammalian target of rapamycin (mTOR) is one of the most important effectors of PI3K/Akt pathway. It is a serine/threonine kinase, and implicated in disease states where growth is deregulated and homeostasis is compromised.

Aims To determine the role of mTOR on the development of corticosteroid insensitivity in COPD and under oxidative stress.

Methods mTOR activity was calculated by the phospho-p70s6k band intensity in Western blot analysis. Corticosteroid sensitivity was determined as the 50% inhibitory concentration of dexamethason on TNF-a-induced interleukin-8 release in U937 cells.

Results mTOR activity was increased within 5minutes after cigarette smoke stimulation in U937 cells, then decreased gradually until below the baseline. mTOR inhibitor, rapamycin, totally suppressed this increase. The EC50 value of dexamethasone was 5.0nM and the Emax value was 62.8 +/- 6.4 %(n=4) in the intact cells, but after incubation with cigarette smoke extract, EC50 was increased to 47.9nM and Emax was decreased to 42.4 +/- 9.1 %, suggesting cigarette smoke decreased dexamethasone sensitivity almost by one-tenth. EC50-Dex was 12.9nM and Emax was 55.9 +/- 6.9 % in the presence of Rapamycin (20nM, 2hr) and rapamycin partially reversed this insensitivity.

Conclusions Cigarrete smoke extract treatments increased mTORC1 activity in U937 cells, and rapamycin partially reversed corticosteroid insensitivity caused by cigarette smoke exposure.
Traffic-Driven Controller-Load-Balancing over Multi-Controller Software-Defined Networking Environment

Field: Computer Science (Physical Sciences)

Currently, more studies are focusing on traffic classification in software-defined networks (SDNs). Accurate classification and selecting the appropriate controller have benefited from the application of machine learning (ML) in practice. In this research, we study different classification models to see which one best classifies the generated dataset and goes on to be implemented for real-time classification. In our case, the classification and regression tree (CART) classifier produces the best classification results for the generated dataset, and logistic regression is also considerable. Based on the evaluation of various algorithmic outputs for the training and validation datasets, and also when execution time is taken into account, the CART is found to be the best algorithm. While testing the impact of load balancing in a multi-controller SDN environment, in different load case scenarios, we observe network performance parameters like bit rate, packet rate, and jitter. Here, the use of traffic classification-based load balancing improves the bit rate as well as the packet rate of traffic flow on a network and thus considerably enhances throughput. Finally, the reduction in jitter while increasing the controllers confirms the improvement in QoS in a balanced multi-controller SDN environment.
Nonprofit to for-profit hospital transactions: all roads lead to the attorney general's office.

Field: Social Sciences (Social Sciences)

As more and more hospitals travel the route from nonprofit to for-profit status, state attorneys general are increasingly playing the role of "traffic cop" along this rough and often contentious road. A better understanding of the attorney general's office and greater rapport with its officers is the "order of the day" for officers and directors looking to orchestrate such a transition.
Survey of Invasive Mosquito Surveillance and Control Capacity in Southeastern USA Reveals Training and Resource Needs

Field: Environmental Science (Physical Sciences)

ABSTRACT Several invasive mosquito species that are nuisances or of medical and veterinary importance have been introduced into the Southeastern region of the USA, posing a threat to other species and the local ecosystems and/or increasing the risk of pathogen transmission to people, livestock, and domestic pets. Prompt and effective monitoring and control of invasive species is essential to prevent them from spreading and causing harmful effects. However, the capacity for invasive mosquito species surveillance is highly variable among mosquito control programs in the Southeast, depending on a combination of factors such as regional geography and climate, access to resources, and the ability to interact with other programs. To facilitate the development of invasive mosquito surveillance in the region, we, the Mosquito BEACONS (Biodiversity Enhancement and Control of Non-native Species) working group, conducted a survey on the capacities of various public health agencies and pest control agencies engaged in mosquito surveillance and control in seven Southeastern states (Alabama, Florida, Georgia, Louisiana, Mississippi, North Carolina, and South Carolina). Ninety control programs completed the survey, representing an overall response rate of 25.8%. We report key findings from our survey, emphasizing the training and resource needs, and discuss their implications for future invasive mosquito surveillance and control capacity building. By increasing communication and collaboration opportunities (e.g., real-time sharing of collection records, coordinated multistate programs), the establishment of Mosquito BEACONS and the implementation of this survey can accelerate knowledge transfer and improve decision support capacity in response to or in preparation for invasive mosquito surveillance and can establish infrastructure that can be used to inform programs around the world.
Formação de jurisprudência administrativa pela ANPD: estudo de casos das sanções aplicadas

Field: Social Sciences (Social Sciences)

This article aims to analyze the administrative assessments applicable by the General Data Protection Law (LGPD) and regulated by the National Data Protection Authority (ANPD), highlighting the first sanction applied by the authority due to a violation of the LGPD. The methodology involves bibliographical research, using LGPD provisions and legal and technical instruments modified by the ANPD as primary sources. This approach included an in-depth analysis of the assessments and their regulatory context, highlighting the guidelines determined by the Authority for their application. Furthermore, analysis of the first sanction applied by the authority offers insights into how Brazil is protecting individuals' privacy rights. In conclusion, the LGPD and the ANPD's actions represent innovative advances in protecting the privacy and personal data of Brazilian citizens. Administrative sanctions play a crucial role in ensuring compliance with the provisions of the law, promoting greater responsibility on the part of organizations and encouraging a culture of data protection.
The Mediating Roles of Organizational Commitment and Job Satisfaction in the Effect of Career Satisfaction on Organizational Citizenship Behavior

Field: Business, Management and Accounting (Social Sciences)

This study aims to examine whether organizational commitment and job satisfaction have mediating roles in the effect of career satisfaction on organizational citizenship behavior. The study was carried out on white-collar workers who were chosen through convenience sampling from private sector companies operating in İzmir/Kemalpaşa Organized Industrial Zone, Turkey. The data from 308 employees were analyzed via structural equation modeling techniques at the IBM Amos 24 statistical program. The results indicated that career satisfaction had a positive effect on the sportsmanship, courtesy, and altruism dimension of organizational citizenship behavior. Also, it was found that job satisfaction and only affective commitment had mediating roles in this relationship.