jimnoneill/paper-to-field-training huggingface dataset:
On the role of H2O2 in the recovery of grapevine (Vitis vinifera cv. Prosecco) from Flavescence dorée disease

Field: Agricultural and Biological Sciences (Life Sciences)

In the present work, we compared hydrogen peroxide (H2O2) localisation and the activities/contents of antioxidant enzymes and metabolites in the leaf tissues of grapevine (Vitis vinifera L. cv. Prosecco) plants showing different sanitary status, namely diseased by Flavescence dorée, healthy or recovered. Polymerase chain reaction analysis revealed that the pathogen associated with Flavescence dorée (proposed as ‘Candidatus Phytoplasma vitis’) was detected in the leaf tissues of symptomatic plants, but was not observed in either the healthy or recovered plants. Hydrogen peroxide accumulated in the phloem plasmalemma of recovered grapevine leaves, but was not detected in either healthy or diseased material. When compared to diseased or healthy plants, recovered plants had distinctly lower extractable levels of catalase and ascorbate peroxidase, two enzymes primarily involved in the scavenging of excess H2O2 generated in different cell compartments. Among healthy, diseased and recovered leaves there was no significant difference in the amount of 2-thiobarbituric acid-reactive substances, which are assumed to reflect the extent of peroxidative breakdown of membrane lipids. Therefore, it is suggested that recovery from Flavescence dorée disease in grapevine might be associated with a long-term, sustained and tissue-specific accumulation of H2O2 in leaves, which reduces numbers or prevents further infection by Flavescence dorée phytoplasma. Recovered grapevine plants might be able to achieve such H2O2 accumulation through a selective and presumably stable downregulation of enzymatic H2O2 scavengers, without altering the levels of other antioxidant systems and without incurring an increased oxidative risk.
Pemanfaatan Platform Merdeka Mengajar terhadap Kompetensi Pedagogik Guru di SMAN 1 Airpura

Field: Social Sciences (Social Sciences)

The curriculum changes that occur are a challenge for teachers in their implementation. Therefore, the Ministry of Education and Culture launched the Independent Teaching Platform with the aim of helping teachers in understanding and implementing the Independent Curriculum. This study aims to determine the use of the Independent Teaching Platform on the pedagogic competence of teachers at SMA Negeri 1 Airpura. This research is a type of evaluative research with a quantitative descriptive approach. The sample in this study amounted to 49 people. The data analysis in this study was carried out descriptively. The results of the research on the use of the Merdeka Mengajar platform on the pedagogic competence of teachers at SMA Negeri 1 Airpura, with a percentage of questionnaire results of 74% on the Inspiration Video feature, 79% on the Independent Training feature, 76% on the Proof of Work feature, 73% on the Student Assessment feature, and 80% on the Teaching Tool feature, it can be concluded that this platform has played a significant role in supporting the development of teachers' pedagogic competence. Overall, this study shows that the Merdeka Teaching platform has been well utilized by teachers at SMA Negeri 1 Airpura. However, there are still several aspects that need to be improved to ensure that all features can be used optimally by all teachers, so that they can be more maximal in improving their pedagogic competence
JULIE FLAVELL and STEPHEN CONWAY, editors. Britain and America Go to War: The Impact of War and Warfare in Anglo-America, 1754-1815. Gainesville: University Press of Florida. 2004. Pp. x, 284. $65.00

Field: Arts and Humanities (Social Sciences)

Julie Flavell and Stephen Conway have edited an intriguing volume that consists of eight original essays on the Anglo-American experience in three wars, the Seven Years' War, the American War of Independence, and the War of 1812. A ninth, and final, essay concerns diplomatic more than military history, yet it is not out of place. It serves as a capstone to the collection by scrutinizing the forging of a new Atlantic state system from the debris left by the two destructive wars that the British and Americans had fought with one another. The bulk of the essays focus on British actions and thought in these wars. Only a provocative piece by Michael Bellesiles, who writes on the War of 1812, considers things from an American perspective. One of the essays, that by C. J. Bartlett and Gene Smith on Britain's naval campaign against the United States in 1814–1815, would be...
Dreaming as a Spiritual Practice

Field: Arts and Humanities (Social Sciences)

This essay gives an overview of the various roles that dreams have played in the world's religious traditions, and describes the major findings of 20th century dream psychology. It then offers different models for integrating traditional religious and modern psychological views of dreams. Three specific areas of integration are discussed: 1) The felt experience of numinosity; 2) Archetypal structures; 3) Existential questions. The essay concludes with reflections on the place of contemporary dream studies in the sociohistorical context of the "war" between religion and science in modern Western culture.
Pustular psoriasis treated with IL-17a antibody secukinumab

Field: Medicine (Health Sciences)

The article presents clinical cases of treatment of acute generalized pustular psoriasis (GPP) with the use of an interleukin IL-17A inhibitor, secukinumab, which showed a remarkable response with almost complete disappearance of pustules after the first injection. To the best of our knowledge, there are limited data in the literature on evaluating the effectiveness of therapy with genetically engineered drugs in the treatment of GPP.
EsiNet: Enhanced Network Representation via Further Learning the Semantic Information of Edges

Field: Computer Science (Physical Sciences)

Network representation learning (NRL) is a crucial method to learn low-dimensional vertex representations to capture network information. However, conventional NRL models only regard each edge as a binary or continuous value while neglecting the rich semantic information on edges. To enhance network representation for Social Relation Extraction (SRE) task, we present a novel deep neural network based model, EsiNet, by learning the structure and semantic information of edges simultaneously. Compared with previous work, EsiNet focuses on further learning the interactions between vertices and capturing the correlations between labels. By jointly optimizing the objective function of these two components, EsiNet can preserve both the semantic and structural information of edges. Extensive experiments on several public datasets demonstrate that EsiNet outperforms other baselines significantly, by around 3% to 5% on hits@10 absolutely.
Investigating the Application and Impact of Laser Etching Technology in the Fabrication of Solar Cells

Field: Engineering (Physical Sciences)

The most crucial initial step in the metallization process of electroplating is the local contact openings in dielectric layers. In this article, an ultraviolet picosecond laser (UV‐ps), is used to open the front and back dielectric layer of the precursor of n‐TOPCon solar cells. By changing the laser parameters and spot overlap rate, the surface morphology of laser etching under different conditions is obtained and characterized by optical microscope and scanning electron microscope. The results indicate that there are three separate laser shock zones in the dielectric layer under the action of Gaussian light spot, and the corresponding ablation mechanisms are proposed. The longitudinal distribution of B element is characterized by secondary ion mass spectrometry to explore the effect of laser on its pn junction. In addition, the electrical characterization of lifetime photoluminescence is measured and calibrated using WCT120, and this indicates that the majority of the amorphous silicon is recrystallized when applying a fast firing oven process, and this hence improve the minority carrier lifetime and implied open‐circuit voltage. The laser damage to the emitter at the laser‐ablated regions is investigated using the emitter saturation current density, J0 laser extracted by WCT120.
Effect and Risk Analysis of New Rural Cooperative Medical System in Guizhou Province under big Data Environment

Field: Health Professions (Health Sciences)

In September 2016, Guizhou Province started the full implementation of the new rural cooperative medical insurance policy.The coverage of NRCMS in the future will be more extensive and its development will be more rapid.As a result, the data of the disease insurance will increase in a faster manner, which is particularly important for the processing and utilization of data.In this paper, according to the current situation of the development of NCMS in Guizhou Province, the current situation of NCMS in Guizhou Province is analyzed.The results show that there are a series of risk problems in the implementation of NCMS, which are both external and internal.The risk put forward the corresponding solution.This paper argues that we should give full play to the advantages of the Internet and establish a unified information system of new rural cooperative medical insurance in the province.With the assistance of big data service platform, we will strengthen the risk control of new rural cooperative medical insurance in Guizhou Province and ensure the continuous and effective operation of new rural medical insurance.
Conversion of etoposide phosphate to etoposide under ambulatory infusion conditions

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective: To determine the extent of conversion of etoposide phosphate, a water-soluble prodrug for etoposide, to etoposide at concentrations and temper atures likely to occur during ambulatory infusion. Design: Etoposide phosphate solutions were prepared at equivalent etoposide concentrations of 15 and 1.5 mg/mL in ambulatory infusion cassettes and stored protected from light at 18 to 20°C and 37°C. Daily samples were taken for 7 days. Main Outcome Measure: Instability was as sessed as percentage conversion of etoposide phos phate to etoposide. Both drugs were measured using high-performance liquid chromatography. Results: At room temperature, there was less than 2% conversion of etoposide phosphate to etopo side. At 37°C, there was a cumulative conversion to etoposide of 6.6% after 7 days at both the low and high concentrations. Conclusion: Etoposide phosphate displays a temperature-dependent, concentration-independent conversion to etoposide over 7 days of less than 7%. Previous studies have confirmed the chemical stabil ity of etoposide up to 96 hours but have suggested that the maximum recommended etoposide concen tration to prevent crystal formation in infusion solu tions is 0.4 mg/mL. To be conservative, if the maxi mum conversion of etoposide phosphate to etoposide over 7 days is estimated to be 10%, and 0.3 mg/mL is selected as the maximum etoposide concentration, then the maximum concentration of etoposide phos phate should be the equivalent of 3.0 mg/mL etopo side. Therefore, prepared under aseptic conditions in a laminar flow cytotoxic safety cabinet, up to 3.0 mg/mL etoposide as etoposide phosphate in 0.9% sodium chloride can be delivered by ambulatory infusion, protected from light, over 96 hours. This will permit therapeutic doses of etoposide, as etopo side phosphate, to be delivered continuously by ambulatory infusion. Given that the extent of conver sion to etoposide was temperature dependent, it is recommended that the infusion cassette remain be low 37°C and preferably as close to room temperature as possible.
Beta-COP is essential for transport of protein from the endoplasmic reticulum to the Golgi in vitro

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Using a novel in vitro assay which allows us to distinguish vesicle budding from subsequent targeting and fusion steps, we provide the first biological evidence that beta-COP, a component of non-clathrin- coated vesicles believed to mediate intraGolgi transport, is essential for transport of protein from the ER to the cis-Golgi compartment. Incubation in the presence of beta-COP specific antibodies and F(ab) fragments prevents the exit of vesicular stomatitis virus glycoprotein (VSV-G) from the ER. These results demonstrate that beta-COP is required for the assembly of coat complexes mediating vesicle budding. Fractionation of rat liver cytosol revealed that a major biologically active form of beta-COP was found in a high molecular pool (> 1,000 kD) distinct from coatomer and which promoted efficient vesicle budding from the ER. Surprisingly, rab1B could be quantitatively coprecipitated with this beta-COP containing complex and was also essential for function. We suggest that beta-COP functions in an early step during vesicle formation and that rab1B may be recruited as a component of a precoat complex which participates in the export of protein from the ER via vesicular carriers.
Stochastic Resonance in a Generalized Quantum Kubo Oscillator

Field: Physics and Astronomy (Physical Sciences)

We discuss stochastic resonance in a biased linear quantum system that is subject to multiplicative and additive noises. Starting from a microscopic system-reservoir Hamiltonian, we derive a c-number analogue of the generalized Langevin equation. The developed approach puts forth a quantum mechanical generalization of the "Kubo type" oscillator which is a linear system. Such a system is often used in the literature to study various phenomena in nonequilibrium systems via a particular interaction between system and the external noise. Our analytical results proposed here have the ability to reveal the role of external noise and vis-a-vis the mechanisms and detection of subtle underlying signatures of the stochastic resonance behavior in a linear system. In our development, we show that only when the external noise possesses a "finite correlation time" the quantum effect begins to appear. We observe that the quantum effect enhances the resonance in comparison to the classical one.
[Efficacy of cimetidine in treatment of Herpes zoster in the first 5 days from the moment of disease manifestation].

Field: Medicine (Health Sciences)

221 patients with Herpes zoster have undergone the treatment. They were given cimetidine in the daily dose 3 x 200 mg and 1 x 400 mg to night. It was proved that the efficacy of the Herpes zoster treatment by cimetidine is inversely proportional to the time of the disease duration. The authors suggest to use cimetidine in the treatment of Herpes zoster virus infections even during the prodromal period.
Cuando Apolo mató a Ganymedes. El “texte .liij.” de la Epistre Othea

Field: Arts and Humanities (Social Sciences)

Christine de Pizan's Epistre Othea aims to show a variety of models about what does it mean to be a perfect knight. In her book she bases on several sources, among which the Ovide moralisé is one of the most important. Thus, it´s surprising that one of the used exempla conspicuously departs from the content of this work (and others that she knew) by introducing an episode in which Apollo kills Ganymede, not only in the text itself but also in the iconographic program that accompanies it in the manuscripts. This article tries to draw attention to this unique feature in order to seek some possible explanation.
Exploring the Teachers’ and Students’ Perceptions Regarding the Impact of Innovative Technologies on Quality Education

Field: Social Sciences (Social Sciences)

This study has been conducted under the Interpretivist paradigm as the inquirer’s intent was to explore the phenomenon in depth. The university teachers (six) and the undergraduate students (Twelve) have been selected purposively for the study. The students were enrolled in the BS Education (Semester-VII) whereas the teachers were those who were teaching to the aforementioned classes. A Semi-Structured interview protocol has been developed and used by the inquirer for the purpose of the data collection. The instrument has been validated through the experts’ opinion before its actual administration to the participants. The collected data has been analyzed with the help of Thematic analysis. On the basis of the results, it is concluded that the teachers feel that incorporating innovative technology into classroom is very beneficial for engaging students and students pay more attention with the help of innovative technologies. Similarly, the students expressed that incorporating innovative technology into classroom is very beneficial for making lectures interesting and engaging.
Genomic Analysis to Elucidate the Lignocellulose Degrading Capability of a New Halophile Robertkochia solimangrovi

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Robertkochia solimangrovi is a proposed marine bacterium isolated from mangrove soil. So far, the study of this bacterium is limited to taxonomy only. In this report, we performed a genomic analysis of R. solimangrovi that revealed its lignocellulose degrading ability. Genome mining of R. solimangrovi revealed a total of 87 lignocellulose degrading enzymes. These enzymes include cellulases (GH3, GH5, GH9 and GH30), xylanases (GH5, GH10, GH43, GH51, GH67, and GH115), mannanases (GH2, GH26, GH27 and GH113) and xyloglucanases (GH2, GH5, GH16, GH29, GH31 and GH95). Most of the lignocellulolytic enzymes encoded in R. solimangrovi were absent in the genome of Robertkochia marina, the closest member from the same genus. Furthermore, current work also demonstrated the ability of R. solimangrovi to produce lignocellulolytic enzymes to deconstruct oil palm empty fruit bunch (EFB), a lignocellulosic waste found abundantly in palm oil industry. The metabolic pathway taken by R. solimangrovi to transport and process the reducing sugars after the action of lignocellulolytic enzymes on EFB was also inferred based on genomic data. Collectively, genomic analysis coupled with experimental studies elucidated R. solimangrovi to serve as a promising candidate in seawater based-biorefinery industry.
On a class of dynamical systems both quasi-bi-Hamiltonian and bi-Hamiltonian

Field: Mathematics (Physical Sciences)

It is shown that a class of dynamical systems (encompassing the one recently considered by F. Calogero [J. Math. Phys. 37 (1996) 1735]) is both quasi-bi-Hamiltonian and bi-Hamiltonian. The first formulation entails the separability of these systems; the second one is obtained trough a non canonical map whose form is directly suggested by the associated Nijenhuis tensor.
Potential use of chitosan nanoparticles for oral delivery of DNA vaccine in black seabream Acanthopagrus schlegelii Bleeker to protect from Vibrio parahaemolyticus

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Abstract To develop an effective and easy‐to‐administer vaccine against vibriosis of fish, the chitosan nanoparticles‐loaded DNA vaccine against Vibrio parahaemolyticus was studied. A DNA vaccine was constructed using the outer membrane protein K ( ompK ) gene of V. parahaemolyticus strain (OS4) and pEGFP ‐N 2 , a eukaryotic expression vector, and the construct was named pEGFP ‐N 2 ‐OMPK ( pDNA ). The pDNA was encapsulated in chitosan particles (chitosan/ pDNA ). The effective diameter, mean diameter and polydispersity of the particles were 284.4 nm, 218.9 nm and 0.160, respectively. Scanning electron microscopy showed that the particles are dispersed as individual nanoparticles with spherical shape of around 200 nm and are homogeneously distributed. Encapsulation efficiency and loading percentage of nanoparticles were 91.5% and 2.08%, respectively. Reverse transcription–polymerase chain reaction (RT‐PCR) showed that RNA‐containing information of the ompK gene existed in mid‐intestine, liver, kidney and muscle 3 weeks after oral administration in black seabream Acanthopagrus schlegelii Bleeker. Expression of the reporter gene, green fluorescent protein ( GFP ), was observed in the above‐mentioned tissues by fluorescence microscopy. Expression of the ompK gene within 3 weeks evoked an immune response. Black seabream was protected from V. parahaemolyticus (OS4), with 72.3% relative percentage survival (RPS) 3 weeks post‐vaccination with chitosan/ pDNA . The direct agglutination test indicated that oral administration with chitosan/ pDNA induced an antibody immune response in fish against V. parahaemolyticus (OS4). Data obtained, here and in other related studies, suggest that chitosan nanoparticles are promising carriers for an oral pDNA vaccine.
Factors associated with happiness and satisfaction with life of medical students in their first four years of a Brazilian private medical school

Field: Psychology (Social Sciences)

Aim: To determine the factors that interfere with students’ perceptions of happiness and satisfaction with life during the initial process of adaptation to the college environment. Material and Methods: This is a cross-sectional study involving students from the first to fourth years of the medical program at a private school in Brazil. The data were collected using an SurveyMonkey. The students completed a questionnaire to assess daily activities and personal characteristics in addition to the Pemberton Happiness Index (PHI) and Satisfaction with Life Scale (SWLS) instruments. Results: The final regression models explained 42.2% and 44.7% of the total variance of the SWLS and PHI scores, respectively. Although personal, school, and out-of-school variables were individually associated with the investigated scores, the personal variables explained most of the score variability overall (57.8% and 55.3% of the SWLS and PHI scores, respectively). Conclusion: This study identified and quantified factors (personal, school, and out-of-school) that could be associated with happiness and satisfaction as medical students. Medical students with positive personality traits such as good health perception, optimism, financial satisfaction, and fulfillment as medical students were happier and more satisfied. We hope that that this research provides data for researchers and medical schools to facilitate pedagogical improvements for student evaluation.
Hepatitis: Intrahepatic Expression of Au Antigenand Immune Complexes in Liver Tissue

Field: Medicine (Health Sciences)

Seventy patients with various liver disorders were studies for the presence of Au antigen in their blood, as well as for the presence of Au antigen, immunoglobulins and complement in their liver. In 18 patients, we could demonstrate Au antigen in the serum; in all of these, Au antigen was also found in the liver. In both Au-positive and Aunegative viral hepatitis cases, we observed granular deposition of IgG and complement in the liver along vessel walls and sinusoids. These findings suggest that immune complexes are involved in the pathogenesis of viral hepatitis.