jimnoneill/paper-to-field-training huggingface dataset:
O3‐09‐03: Longitudinal reduction in blood pressure in hypertensive individuals is associated with increased levels of biomarkers for Alzheimer's disease

Field: Neuroscience (Life Sciences)

In hypertension (HTN), cerebral blood flow (CBF) regulation limits are changed and the blood pressure (BP) threshold at which CBF is safely maintained is higher. This shift may increase the brain's vulnerability to hypoperfusion at lower BP. Despite growing recognition of the link between hypoperfusion and neurodegeneration little is known about whether blood pressure reductions can induce deficient perfusion and promote expression of cerebrospinal fluid (CSF) biomarkers of amyloid and neurofibrillary pathology. We investigated the relationship between longitudinal changes in mean arterial pressure (MAP) and CSF biomarkers of Alzheimer's disease in a group of cognitively healthy elderly with and without HTN. Longitudinal assessments of blood pressure (MAP), CSF p-tau181 (phosphorylated tau), total tau, amyloid ß 1-42 (Aß42), cognition and whole brain volume were conducted on average 2.0±0.6 years apart in a group of 77 cognitively healthy elderly (age 63.4±9.4, range 44-86 years; education 16.9±2.1, range 10-22 years; 60% women). MAP was calculated as: 1/3 systolic blood pressure + 2/3 of diastolic blood pressure. At baseline HTN was found in 23 individuals (30%). When longitudinal change (ˆ†) in p-tau181 was predicted with the ˆ†MAP, HTN, and the HTNxˆ†MAP interaction, both the total model (F 3,73=3.9, p=.01), and the interaction term (p=.01) were significant. These data indicate that the relationship between ˆ†MAP and ˆ†p-tau181 was strongly dependent on the presence or absence of HTN. Only in the HTN group was a decrease in MAP from baseline to follow-up related to an increase in p-tau181 (r=-0.5, p=.01). In addition, only among subjects with HTN, was a reduction in MAP related to the worsening of verbal episodic memory (r=0.46, p=.03). Finally in the entire group the increase in p-tau181 was associated with reduction in the verbal episodic memory score (ß=-.223, p=.048). No relationship was observed between changes in MAP and whole brain volume. In subjects with HTN, MAP reduction is associated with increased CSF p-tau181 and deterioration of episodic memory, possibly resulting from suboptimal perfusion and subsequent accumulation of neurofibrillary tangles. Prior experimental work has demonstrated a relationship between perfusion, energetic reductions and tauopathy.
COMPETENTA DE SOLUTIONARE A CERERII DE DIVORT POTRIVIT REGULAMENTULUI NR. 2201/2003 AL UNIUNII EUROPENE

Field: Arts and Humanities (Social Sciences)

The starting point of the article is a Romanian judgement stating that dipositions of article 3 paragraph (1) letter a) of the EC Regulation No. 2201/2003 have an exclusive application in relation with the provisions of letter b) of the same article and paragraph, with the consequence that none of the Romanian courts are competent to judge a divorce introduced by a Romanian national against the spouse with the same nationality, both living in Italy. The author proves the statement wrong, starting with the history of the Regulation (EC) No. 2201/2003 and ending with the Greenpaper drawn in 2005 for further improvements of the regulations in family matters.
Growth, Development, Reproduction, Physiological and Behavioural Studies on Living Organisms, Human Adults and Children Exposed to Radiation from Video Displays

Field: Medicine (Health Sciences)

Various living organisms, human workers and children were tested for any biological action resulting from exposure to radiation from video display terminals (VDTs). VDTs were powered by a 50-Hz alternating volt age of 220 V. Measured electric and magnetic fields were 13 V/M and 50 nT, respectively. Living organisms were maintained under their normal breeding conditions and control values were obtained before switching on the VDT. Various effects related to the irradiation time were demonstrated, i.e. growth delay in algae and Drosophila, a body weight deficiency in rats, abnormal peaks of mor tality in Daphnia and Drosophila, teratological effects in chick embryos and behavioural disturbances in rats. The embryonic and neonatal periods showed a high sensitiv ity to the VDT radiation. In humans, after 4 h of working in front of a VDT screen, an increase in tiredness and a decrease in the resistance of the immune system were observed in workers. In prepubertal children, 20 min of exposure were sufficient to induce neuropsychological disturbances; pre-pubertal young people appear to be particularly sensitive to the effect of the radiation. ln human testicular biopsies cultured in vitro for 24 h in front of a VDT screen, mitotic and meiotic disturbances, the appearance of degeneration in some aspects of the cells and significant disorganisation of the seminiferous tubules were demonstrated and related to modification of the metabolism of the sample. An experimental appa ratus has been developed and tested that aims to pre vent the harm from VDT radiation. Known commercially as the emf-Bioshield®, it ensures effective protection against harmful biological effects of VDT radiation.
Carbon Steel Tubing for General Use - Understanding Nondestructive Testing for Carbon Steel Tubing

Field: Engineering (Physical Sciences)

<div class="section abstract"> <div class="htmlview paragraph">This SAE information report provides a means to understand the various methods of evaluating the integrity of steel tubing without the need of destroying the tubing. This report describes eddy current testing, flux leakage testing, ultrasonic testing, and magnetic particle testing of steel tubing. The primary purpose of these methods of testing steel tubing is to look for flaws in the tubing, such as discontinuities, seams, cracks, holes, voids and other imperfections characteristic to the specific construction of the tubing.</div> </div>
Analisis Faktor Yang Berhubungan Dengan Kinerja Perawat Dalam Pengisian Rekam Medis Elektronik Di Ruang Rawat Inap Rs Bhayangkara TK. II Hoegeng Imam Santoso Banjarmasin

Field: Health Professions (Health Sciences)

Medical records are essential to health services. In Indonesian hospitals, RME is utilized to a degree of 65%. The Bhayangkara TK III Hoegeng Imam Santoso Hospital in Banjarmasin has RME filling completeness rates that range from 42% in the inpatient room to less than 60% between August and December. evaluating how well nurses performed in filling out electronic medical records in the inpatient room of Bhayangkara Hospital TK III Hoegeng Imam Santoso Banjarmasin by looking at knowledge, tenure, work motivation, and job design. This study used a cross sectional design. The research subjects consisted of 42 nurses in the inpatient room of Bhayangkara TK III Hoegeng Imam Santoso Hospital Banjarmasin Data analysis of chi square test and multiple logistic regression test. The results of the analysis with chi square showed the p value of knowledge (p = 0.000), tenure (p = 0.4390, work motivation (p = 0.032), and job design (p = 0.004). Knowledge variable is most associated with nurse performance (Exp(B)= 14.993. There is a relationship between knowledge, work motivation, and job design. There was no relationship between length of service and nurses' performance in filling out electronic medical records in the inpatient room of Bhayangkara Hospital TK III Hoegeng Imam Santoso Banjarmasin. The most dominant variable is knowledge
Concurrent software engineering: prospects and pitfalls

Field: Computer Science (Physical Sciences)

Software development remains largely a sequential, time-consuming process. Concurrent engineering (CE) principles have been more widely adopted and with greater success in hardware development. In this paper, a methodology for marrying CE principles to software engineering, or concurrent software engineering (CSE), is proposed. CSE is defined as a management technique to reduce the time-to-market in product development through simultaneous performance of activities and processing of information. A hierarchy of concurrent software development activity is defined, ranging from the simplest (within stage) to the most complex (across products and platforms). The information support activities to support this activity hierarchy are also defined, along with two key linking concepts-synchronicity and architectural modularity. Principles of CSE are developed for each level in the activity hierarchy. Research findings that establish limitations to implementing CE are also discussed.
Role of the Endocannabinoid/Endovanilloid System in the Modulation of Osteoclast Activity in Paget’s Disease of Bone

Field: Medicine (Health Sciences)

The role of the endocannabinoid/endovanilloid (EC/EV) system in bone metabolism has recently received attention. Current literature evidences the modulation of osteoclasts and osteoblasts through the activation or inhibition of cannabinoid receptors in various pathological conditions with secondary involvement of bone tissue. However, this role is still unclear in primary bone diseases. Paget’s disease of the bone (PDB) could be considered a disease model for analyzing the role of the EC/EV system on osteoclasts (OCs), speculating the potential use of specific agents targeting this system for managing metabolic bone disorders. The aim of the study is to analyze OCs expression of EC/EV system in patients with PDB and to compare OCs activity between this population and healthy people. Finally, we investigate whether specific agents targeting EC/EV systems are able to modulate OCs activity in this metabolic bone disorder. We found a significant increase in cannabinoid receptor type 2 (CB2) protein expression in patients with PDB, compared to healthy controls. Moreover, we found a significant reduction in multi-nucleated tartrate-resistant acid phosphatase (TRAP)–positive OCs and resorption areas after treatment with JWH-133. CB2 could be a molecular target for reducing the activity of OCs in PDB, opening new therapeutic scenarios for the management of this condition.
A Dynamic Example of Delivering Patient Management Identification Opportunities Using SAS/IntrNet®

Field: Health Professions (Health Sciences)

This SAS/IntrNet application provides instant access to almost 5 million health claim and clinical information records. It is designed to focus and prioritize patients for interaction through Aetna's behavioral health case management and disease management programs. Through the company intranet, nurse case managers have the ability to search for patients by program, service area, employer (plan sponsor), or Aetna office. A submitted search produces a prioritized list of patients meeting criteria provided to the search form. Each patient is listed with relevant data to help the nurse select a patient in need of interaction. A drill-down into claims, disease identification information, demographics, risk levels, and clinical markers allows the nurse to decide whether this patient should be contacted. Then an assignment decision can be executed within the tool and the patient's status may be tracked. This application uses the flexibility of SAS/IntrNet, the SAS Macro Language, dataset indexes, and the data step in combination with web browser features such as HTML and JavaScript to create a dynamic set of forms and web reports. This paper will explore the process of combining a dynamic SAS application with local intranet standards, and along the way demonstrate how we can write HTML with SAS.
Remote Permission Management in Third-Party Tools and e-Learning Systems

Field: Computer Science (Physical Sciences)

This paper deals with the problem of improving the tailorability and extensibility of current Learning Management Systems by allowing them to use third-party tools. Nowadays there are several initiatives to integrate in e-Learning systems tools deployed by external providers following the Software as a Service distribution model. However, these initiatives achieve at best a very "soft" integration. In this article we discuss the issues that should be addressed to achieve a tighter integration between the Learning Management System and the tool, and put the focus on one of them: the remote management of permissions from the Learning Management System.
Deep Learning-Based Named Entity Recognition from Construction Safety Regulations for Automated Field Compliance Checking

Field: Computer Science (Physical Sciences)

Automated safety compliance checking aims to detect field violations to construction safety regulations. Recent research and system development efforts have made good progress on automated tracking of labor and equipment towards improved violation detection and safety compliance. However, extracting and modeling safety requirements for supporting automated violation detection or safety alert systems remains highly manual. Towards addressing this gap, information extraction provides an opportunity to automatically extract safety requirements from regulatory documents for comparisons with field information to detect violations. However, existing information extraction methods fall short in their scalability and/or accuracy. To address this need, this paper proposes a deep learning-based information extraction method for extracting entities that describe fall protection requirements from construction safety regulations for supporting automated field compliance checking. The proposed method uses a hybrid bidirectional long short-term memory (BiLSTM) and convolutional neural network (CNN) model for recognizing the entities. The proposed method was implemented and tested on four selected Occupational Safety and Health Administration (OSHA) sections related to fall protection. It has achieved an average precision, recall, and F-1 measure of 81.5%, 80.3%, and 80.9%, respectively, which indicates good named entity recognition performance. The paper discusses the proposed method and experimental results, and outlines directions for further performance improvement.
Polycyclic aromatic hydrocarbons and molecular equilibria in carbon-rich stars

Field: Physics and Astronomy (Physical Sciences)

view Abstract Citations (58) References (36) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Polycyclic Aromatic Hydrocarbons and Molecular Equilibria in Carbon-rich Stars Cherchneff, Isabelle ; Barker, John R. Abstract Thermal equilibrium (TE) molecular concentrations are computed for several carbon-rich elemental compositions and various total gas pressures. Such calculations may be used to estimate the molecular abundances in a carbon-rich stellar photosphere and its vicinity. The six elements and seventy molecules considered include observed molecules and radicals, polycyclic aromatic hydrocarbons (PAHs) up to the size of coronene, long-chain hydrocarbons, the cyanopolyyne group, and complex ring compounds. The thermodynamic data used are from the recent literature or are estimated. Condensations of graphite, silicon carbide, and quartz are also considered. The results show that long-chain hydrocarbons are abundant at moderate temperatures. PAHs also form in significant amounts at low temperatures, but only benzene survives graphite condensation. TE molecular profiles are obtained for the inner region of an envelope model representative of late-type stars. Publication: The Astrophysical Journal Pub Date: August 1992 DOI: 10.1086/171624 Bibcode: 1992ApJ...394..703C Keywords: Carbon Stars; Hydrocarbons; Thermodynamic Equilibrium; Abundance; Gas Pressure; Molecular Physics; Photosphere; Stellar Atmospheres; Stellar Envelopes; Astrophysics; MOLECULAR DATA; MOLECULAR PROCESSES full text sources ADS |
Rate of convergence of attractors for semilinear singularly perturbed\n problems: parabolic equations with large diffusion

Field: Mathematics (Physical Sciences)

We exhibit a singularly perturbed parabolic problems for which the asymptotic\nbehavior can be described by an one-dimensional ordinary differential equation.\nWe estimate the continuity of attractors in the Hausdorff metric by rate of\nconvergence of resolvent operator.\n
Lung &amp; Gynecological Cancers: Has COVID-19 Impacted Patients?

Field: Medicine (Health Sciences)

<p>Coronavirus disease- 2019 (COVID-19) presented as case of viral pneumonia of unknown etiology is diagnosed by Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) test of the samples from upper and lower respiratory tract. It can present as a mild flu-like illness for healthy adults yet it may become a life-threatening disease for the immunocompromised, such as cancer patients, by predisposing them to respiratory pathogens which may manifest as life-endangering pneumonia. Physicians should carefully evaluate their patient&rsquo;s disease process and tailor treatment for individual patients to ensure that before doing beneficence, no further harm is done. Whether this is a wrinkle in time or the new normal, time will tell, but in light of recent evidence, &lsquo;extra&rsquo; caution is the way forward.</p>
Exploring the Influence of Perceived Usefulness and Ease of Use of Social Media Influencers on Skincare Product Purchases: A Technology Acceptance Model (TAM) Perspective

Field: Business, Management and Accounting (Social Sciences)

The purpose of this study is to determine how perceived usefulness (PU) and perceived ease of use (EOU) of social media influencer (SMI) material affect consumers' purchase intentions for skincare products. Using the Technology Acceptance Model (TAM), the study looks at how consumers react cognitively and behaviorally to influencer-generated material, specifically in terms of practical utility and ease of use. Two hypotheses were proposed: first, that perceived usefulness considerably influences purchase intentions, and second, that perceived simplicity of use has a major impact on buy intentions. A quantitative study design was used, with a structured questionnaire as the major data collection tool. The study used purposive sampling to recruit 500 respondents from urban and semi-urban areas of Haryana, India. The respondents were engaged social media users who frequently saw skincare content promoted by influencers. The survey instrument included 20 items measuring PU and EOU, which were adapted from prior TAM-based studies to fit the context of skincare influencer marketing. Confirmatory Factor Analysis (CFA) was used to validate the constructs, and reliability was validated by Cronbach's alpha coefficients greater than 0.7. A multiple linear regression analysis was then used to investigate the association between PU, EOU, and purchase intention. The regression model had a statistically significant R² value of 0.48, indicating that PU and EOU explained 48% of the variance in purchase intention. PU showed a larger standardized beta value (β = 0.55, p < 0.001) than EOU (β = 0.29, p < 0.001), indicating more predictive potential in affecting consumer behavior.The findings indicate that when influencer material is seen as useful, relevant, and easy to engage with, customers are more likely to purchase skincare goods. These findings highlight the importance of TAM in the context of digital marketing and provide practical insights for influencers and brand managers looking to improve their content strategy.
C. difficile may be overdiagnosed in adults and is a prevalent commensal in infants

Field: Medicine (Health Sciences)

Abstract Clostridioides difficile is an urgent threat in hospital-acquired infections world-wide, yet the microbial composition associated with C. difficile, in particular in C. difficile infection (CDI) cases, remains poorly characterised. To investigate the gut microbiome composition in CDI patients, we analysed 534 metagenomes from 10 publicly available CDI study populations. We then tracked C. difficile on a global scale, screening 42,900 metagenomes from 253 public studies. Among the CDI cohorts, we detected C. difficile in only 30% of the stool samples from CDI patients. However, we found that multiple other toxigenic species capable of inducing CDI-like symptomatology were prevalent. In addition, the majority of the investigated studies did not adhere to the recommended guidelines for a correct CDI diagnosis. In the global survey, we found that C. difficile prevalence, abundance and biotic context were age-dependent. C. difficile is a rare taxon associated with reduced diversity in healthy adults, but common and associated with increased diversity in infants. We identified a group of species co-occurring with C. difficile exclusively in healthy infants, enriched in obligate anaerobes and in species typical of the healthy adult gut microbiome. C. difficile in healthy infants was therefore associated with multiple indicators of healthy gut microbiome maturation. Our analysis raises concerns about potential CDI overdiagnosis and suggests that C. difficile is an important commensal in infants and that its asymptomatic carriage in adults depends on microbial context.
Conceptualizing the role of social accountability in public service delivery: a comparative study of Bangladesh, India, and Pakistan

Field: Social Sciences (Social Sciences)

This chapter explores the effectiveness of social accountability initiatives in improving public service delivery in Bangladesh, India and Pakistan. Drawing upon relevant and contemporary literature, a conceptual model is developed in order to assess and compare the current state of social accountability in these three South Asian countries. The findings reveal that the effectiveness of social accountability initiatives for improving public service delivery depends on the synergy between demand and supply-driven mechanisms. There is also considerable impact of the political climate, the strength of civic groups and the appropriate institutional sphere on the outcomes of social accountability intervention.
Breeding of early maturing apricot cultivar Zaojinyan.

Field: Agricultural and Biological Sciences (Life Sciences)

Zaojinyan is an extremely early maturing apricot cultivar derived from the cross combination of Yangshao as male parent.The fruit shape of Zaojinyan is nearly circular with clean appearance,smooth fruit surface and bright golden yellow.The flesh is juicy,sweet,fragrant,fine with very less fiber,containing soluble solids 15.6%.Edible rate is 96.5%.The variety is precocious and productive with good adaptability.The maturity date is around Mid-may in Zhengzhou,Henan province.The fruit development period is about 55 days.