jimnoneill/paper-to-field-training huggingface dataset:
Artemisia argyi-Mediated Synthesis of Monodisperse Silver Nanoparticles as Components of Bioactive Nanofibrous Dressings with Dual Antibacterial and Regenerative Functions

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The effective healing of chronic wounds requires balancing antimicrobial activity with tissue regeneration. In this study, we developed a novel, eco-friendly synthesis method using Artemisia argyi extract to produce silver nanoparticles (AgNPs), addressing toxicity concerns associated with conventional chemical synthesis methods. Through optimization of multiple synthesis parameters, monodisperse spherical AgNPs with an average diameter of 6.76 ± 0.27 nm were successfully obtained. Plant-derived compounds from Artemisia argyi extract acted as efficient mediators for both reduction and stabilization, yielding nanoparticles with high crystallinity. The synthesized AgNPs exhibited potent antibacterial activity against both Gram-negative and Gram-positive bacteria, with minimum inhibitory concentrations of 8 μg/mL against Escherichia coli and 32 μg/mL against Staphylococcus aureus, while maintaining high biocompatibility with L929 fibroblasts at concentrations ≤ 8 μg/mL. When integrated into polylactic acid/collagen type I (PLA/Col1) nanofibrous matrices, the optimized 0.03% AgNPs/PLA/Col1 dressing significantly accelerated wound healing in a diabetic rat model, achieving 94.62 ± 2.64% wound closure by day 14 compared to 65.81 ± 1.80% observed in untreated controls. Histological analyses revealed a dual-functional mechanism wherein controlled silver ion release provided sustained antibacterial protection, while concurrently promoting tissue regeneration characterized by enhanced collagen deposition, reduced inflammation, and increased neovascularization. This innovative approach effectively addresses critical challenges in diabetic wound care by providing simultaneous antimicrobial and regenerative functions within a single biomaterial platform.
Local banks : going regional

Field: Business, Management and Accounting (Social Sciences)

Local banks in Singapore are facing stiff competition in the domestic market. As such, the local banks are moving their resources to the regional countries as they offer vast business opportunities. In order to establish their presence in the foreign countries, they need to formulate a set of regionalisation strategy. Having identified the strategies adopted by local banks and the business opportunities in the region, we have come up with a set of recommendation as to the procedures and strategies local banks need to implement to effectively enter the foreign markets.
HLA-DR Expression on Monocyte Subsets in Critically Ill Children

Field: Medicine (Health Sciences)

Background: To longitudinally study blood monocyte subset distribution and human leukocyte antigen-DR (HLA-DR) expression on monocyte subsets in children with sepsis, post-surgery and trauma in relation to nosocomial infections and mortality. Methods: In 37 healthy children and 37 critically ill children (12 sepsis, 11 post-surgery, 10 trauma and 4 admitted for other reasons)—participating in a randomized controlled trial on early versus late initiation of parenteral nutrition—monocyte subset distribution and HLA-DR expression on monocyte subsets were measured by flow cytometry upon admission and on days 2, 3 and 4 of pediatric intensive care unit (PICU) stay. Results: Upon PICU admission, critically ill children had a higher proportion of classical monocytes (CD14++CD16−) than healthy children [PICU 95% (interquartile range [IQR] 88%–98%); controls, 87% (IQR 85%–90%), P < 0.001]. HLA-DR expression was significantly decreased within all monocyte subsets and at all time points, being most manifest on classical monocytes and in patients with sepsis. Percentage of HLA-DR expressing classical monocytes [upon PICU admission 67% (IQR 44%–88%); controls 95% (IQR 92%–98%), P < 0.001], as well as the HLA-DR mean fluorescence intensity [upon PICU admission 3219 (IQR 2650–4211); controls 6545 (IQR 5558–7647), P < 0.001], decreased during PICU stay. Patients who developed nosocomial infections ( n = 13) or who died ( n = 6) had lower HLA-DR expression on classical monocytes at day 2 ( P = 0.002) and day 3 ( P = 0.04), respectively. Conclusions: Monocytic HLA-DR expression decreased during PICU stay and was lower compared with controls on all examined time points, especially on classical monocytes and in children admitted for sepsis. Low HLA-DR expression on classical monocytes was associated with nosocomial infections and death.
Lysis of human macrophages by cytolytic CD4+ T cells fails to affect survival of intracellularMycobacterium bovis-bacille Calmette-Guérin (BCG)

Field: Immunology and Microbiology (Life Sciences)

SUMMARY Human CD4+, mycobacteria-specific, cytolytic T cell clones were used to lyse BCG-infected macrophages. and the effect on the subsequent growth and viability of the organisms was examined. The survival of released bacteria following cell lysis was assessed by both 3H-uridine labelling and colony-forming unit (CFU) estimation. The results indicate that even when effective antigen-specific or lectin-mediated cytolysis of the infected macrophages was achieved, there was no evidence for a direct mycobactericidal effect on the intracellular bacteria. This remained the case even if the period of co-culture of T cells and macrophages was extended up to 48 h. Pretreatment of the macrophages with interferon-gamma (IFN-γ) was not able to act together with T cell-mediated lysis to produce inhibition of mycobacterial growth.
UNIVERSITY LIBRARIES IN PROJECT 5-100, OR THREE YEARS BEFORE...

Field: Social Sciences (Social Sciences)

In this paper, we present a methodology and results of the study aimed at identifying the role of university libraries in the implementation of Project 5-100 and the line of their development. Issues of the government’s policy strategy concerning development of library science are addressed. Results of monitoring of university roadmaps for the implementation of Project 5-100 found in open sources and anonymous questioning of representatives of libraries of these universities are given. Participation of university libraries in the development and implementation of Project 5-100 is considered. In conclusion, the question is raised about the need to find ways to adapt traditional library technologies to new realities and change the personnel policy in the library field.
Gall bladder perforation and biliary peritonitis in a young pregnant lady.

Field: Medicine (Health Sciences)

A rare event of acute free perforation of gall bladder with biliary peritonitis in a case of calculous cholecystitis in a 28 years old pregnant lady occurring in the absence of the usual factors associated with gall stone disease is reported. The clinical features resembled acute appendicitis and a pre-operative diagnosis could not be made. It is suggested that a thorough attempt should be made to exclude conditions mimicking appendicitis, including those of the biliary system, on finding a normal appendix at emergency appendicectomy without hesitating to convert to full laparotomy if required.
Pengaruh Financial Distress, Volatilitas Arus Kas , Firm Size, Leverage Terhadap Keputusan Hedging dengan Likuiditas Sebagai Pemoderasi

Field: Business, Management and Accounting (Social Sciences)

In the context of global economic uncertainty, companies face significant exchange rate risks that can affect their cash flow stability and operational continuity. One strategy to manage this risk is through hedging, which has become increasingly relevant, particularly for companies involved in international trade. This study focuses on how financial distress, cash flow volatility, firm size, and leverage influence hedging decisions, with liquidity as a moderating variable. This research employs multiple linear regression analysis using data from the financial statements of automotive sector companies listed on the Indonesia Stock Exchange (IDX) during the 2019-2023 period. The sample was selected using purposive sampling based on specific criteria. The results of the study show that financial distress, cash flow volatility, firm size, and leverage have a simultaneous and combined effect on hedging decisions. Financial distress and leverage have a positive and significant influence on hedging. Meanwhile, cash flow volatility and firm size have a positive but not significant influence on hedging decisions. Liquidity was found to only enhance the positive impact of financial distress, while the other three variables—cash flow volatility, firm size, and leverage—did not significantly strengthen the hedging decisions.
User awareness and satisfaction of mobile application for the public service of Seoul city

Field: Social Sciences (Social Sciences)

공공 서비스의 공공 앱을 통해 넓게 분산된 시민들에게 다양하고 풍부한 공공 서비스를 고르게 제공할 수 있고, 시민들은 시간과 장소에 구애받지 않고 공공 서비스를 이용할 수 있다는 점에서, 공공 앱을 주요한 공공 서비스 전달 수단으로 인식 하고, 공공 앱의 내용과 기능을 파악함으로써 모바일 정부에 대한 이해를 높이고 정책적 시사점을 제공한다. 현재 모바일에서 사용되고 있는 앱 45개를 토대로 서울시 공공 서비스 사례 분석을 통해 공공 서비스용 모바일 증강 현실 앱의 서비스 유형에는 4가지로 나눌 수 있으며, 정보, 커뮤니케이션, 엔터테인먼트, 안전으로 나눌 수 있었다. 안전한 스마 트 공공 서비스 환경 및 개인 정보 보호 등이 강화돼야 할 것이다. 이러한 공공서비스의 문제점을 제시하고 모바일 공공 서비스에 대한 인식과 만족도에 대한 가이드라인을 제시하고자 한다.
Nitrogen Balance in Paddy Soil of Control-Release Fertilizer Application

Field: Agricultural and Biological Sciences (Life Sciences)

The increasing of greenhouse gases may change agricultural environment. The agronomic productivity will depend upon change of temperature, precipitation, solar radiation and fertilization. Particularly, nitrogen fertilization considerably influences rice productivity and agricultural environments. This experiment was conducted to study transformation of nitrogen and to determine the primary yield components responsible for yield differences in paddy soil. concentration of NPK plot in surface water of paddy soil was at 5 days after transplanting, and then was decreased sharply due to rice absorption and loss to environment. concentration of NPK plot in surface water was at 10 days after transplanting. concentration range of CRF plot in surface water was at 30th after transplanting. The accumulation of volatilization in NPK plot was , which accounted for 20% of N fertilizer applied but using of CRF fertilizer can reduce volatilization by 67% in paddy soil. Use efficiency of N fertilizer was not different between CRF70% and CRF100% plot. Rate of N use efficiency were 27.4%, 51.2%, 49.0% in paddy field NPK, CRF70% and CRF100% plots respectively. The yield of CRF70% showed the best effect with 9.3% increase production ratio, compare with NPK plot.
Techno-economic evaluation of electrocoagulation for Cattell slaughterhouse wastewater treatment using aluminum electrodes in batch and continuous experiment

Field: Environmental Science (Physical Sciences)

Abstract This study aimed to investigate, from technoeconomic point of view, cattle slaughterhouse wastewater (CSWW) treatment via electrocoagulation (EC) technique. A novel lab scale electrocoagulation unit with 3L volume was manufactured and tested. The EC unite contains nine identical cylindrical shape electrodes from aluminum material in connection with controllable DC power supply. Investigation of optimum operating parameters in terms of pH, current density (CD), contact time and electrolyte concentration (TDS) was carried out in batch mode then applied for continuous mode. At each batch, cost analysis was calculated in terms of consumption electrode material and electrical power. The optimum operating conditions at which best removal rate achieved was pH 7, contact time 75 min, TDS = 3000 mg L − 1 and CD of 4 mA.cm − 2 . After application of these conditions on continuous flow mode, the removal rate of Chemical oxygen demand (COD), color, turbidity, biological oxygen demand (BOD), and oil, grease were 95.3%, 99.8%, 98.7%, 96.5% and 94.5% respectively. The total electrode consumption and electrical consumption were 0.6 kg m − 3 and 0.87kWh m − 3 with operational cost about 1.5$ m − 3 . This proved that EC is techno-economically effective treatment method than other conventional treatment methods for high-rate removal of pollutants of from CSWW.
Morality‐ and identity‐related antecedents of children's guilt and shame attributions in events involving physical illness

Field: Psychology (Social Sciences)

It is theorised that guilt- and shame-related appraisals vary on two separate dimensions. Guilt implies an appraisal that one has either committed a moral transgression or that one has otherwise been involved in the creation of a morally wrong outcome. Shame implies one's appraisal that the current event or condition reflects negatively on one's identity. To test these claims, 206 7- to 16-year-old children gave shame and guilt ratings of three types of events that were drawn from the domain of physical illness and that were designed to elicit primarily guilt, primarily shame, or both emotions. The 12-year-olds and older children's ratings were fully consistent with our hypothesis. Younger children's greatest difficulty was in not attributing shame to protagonists who were involved in causing a moral wrong without there being the threat of an unwanted identity. © 2004 Psychology Press Ltd.
Network Analysis on Associative Words and Definitions of 'Electricity' Terminology of Education University Students

Field: Psychology (Social Sciences)

이 연구의 목적은 네트워크 분석법을 활용하여 '전기' 용어에 대한 연상 단어 및 정의에 사용한 핵심 단어가 무엇인지 확인하고, 핵심 단어들이 어떻게 활성화되어 인지 구조를 이루는지 알아보는 데 있다. 연구대상은 지방 소재 교육대학교 1학년 대학생 총 83명으로 하였다. 대학생들의 성별과 고등학교 때 물리 과목 이수 여부에 따라 수업 전과 수업 후로 나누어 '전기' 용어에 대한 연상 단어 및 정의를 네트워크 분석하였다. 연구 결과 대학생들이 '전기'하면 가장 많이 떠올리는 단어는 수업 전 '에너지'이고 수업 후에는 '전류', '전자'이다. 그리고 '전기' 정의에 가장 많이 사용한 단어는 수업 전 '에너지', '흐름', '전자'이고 수업 후에는 '전자', '이동', '전하' 이다. '전기' 용어의 연상 단어에는 성별과 고등학교 때 물리 과목 이수 여부에 따라 조금 다른 네트워크 구조를 이루고 있었지만, 수업 후에는 대학생들의 특성에 상관없이 비슷한 네트워크 구조를 보였다. '전기' 용어의 정의에서는 수업 전 성별에 따라서는 비슷한 네트워크 구조를 갖고 있었고, 고등학교 때 물리 과목 이수 여부에 따라서는 조금 다른 네트워크 구조를 보였다. 하지만 수업 후에는 대학생들의 특성에 상관없이 비슷한 네트워크 구조가 나타났다. 끝으로 대학생들의 '전기' 용어에 대한 네트워크 분석 결과에 대한 교육적 시사점을 논의하였다. This research aimed to identify core words used as associative words and definitions for expressing 'electricity' terminology and to find how core ones are activated to form a cognitive structure, using network analysis. The participants targeted 83 university freshmen students in the University of Education located in suburbs. Depending on their gender, whether or not they completed physics in high school, the associative words and definitions were analyzed using the network method, classifying two sections: before-lesson and after-lesson. The result is as follows: At before-lesson associative words for 'electricity' terminology, a slightly different network construction was revealed based on their two properties. However, after the class, they showed similar network structure irrespective of their distinctive characteristics. When it comes to other 'electricity' definitions, before taking the course, they had similar network connection across the gender but based on physics education status, there appeared subtle differences. Ultimately, after the class they demonstrated similar network structure regardless of their features. In conclusion, this paper suggests educational implications on network analysis, which covers 'electricity' terminology of university students.
Effectiveness of Covid-19 Vaccination on BA.4/BA.5 Variant: A Review of Current Literature

Field: Medicine (Health Sciences)

The B.1.1.529 (Omicron) variant of SARS-CoV-2 has rapidly spread with many variants like BA.1, BA.2, BA3., BA4., and BA5. With sublineages as well. It (Omicron) was first discovered in November 2021 and has become the predominant variant in several nations. Due to the sensitivity of infection and various other limitations like no particular real-time data for different age groups, there is a lack of information on the actual efficacy of vaccines against this variant. Limitations of data and reviews and the incidence of emergence rather than hospitalized people would result in an underestimation of the efficacy of vaccines against severe diseases. This systematic review was conducted by following PRISMA guidelines. Specific inclusion and exclusion parameters were strictly followed. Our studies show that a substantial number of people have received mRNA COVID-19 vaccine doses. The booster dose must be administered and obtained immediately before all efforts to stop the pandemic go to waste. Focusing on the primary vaccination is no longer sufficient.
Efficient autointegration of avian retrovirus DNA in vitro

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

We have developed a cell-free system for an avian retrovirus that promotes autointegration, one-long-terminal-repeat (LTR) circle formation, and correct integration into exogenous target DNA. In this system, autointegration and one-LTR circle formation occurred far more frequently than integration into exogenous target DNA. Autointegration had the same characteristics of normal integration into target DNA except in its selection of target. Highly efficient autointegration as well as one-LTR circle formation in vitro suggest that there may be a mechanism to prevent these processes in vivo.
Penguatan Branding UMKM Puspazary Melalui Inovasi Kemasan Dan Pemasaran Digital

Field: Business, Management and Accounting (Social Sciences)

Improving the competitiveness of Micro, Small, and Medium Enterprises (MSMEs) is a primary focus in this digital era. This research explores efforts to enhance the branding of Puspazary MSMEs through packaging innovation and digital marketing strategies. The collaborative approach involves updating packaging design through re-branding photoshoots and digital marketing via Instagram. Through a two-month internship, the team focused on introducing the MSME, accessory production, marketing strategy analysis, content creation, and participation in innovation development. During the internship, re-branding photoshoots were implemented, packaging innovation by transitioning from cardboard to transparent ziplock, and digital marketing through Instagram. The results of these activities created a more attractive branding and increased competitiveness for Puspazary MSMEs, emphasizing the importance of innovative branding strategies in supporting MSME sustainability amid global market dynamics. The conclusion highlights the positive outcomes of implementing packaging and digital marketing innovations, while recommendations involve the continued development of digital-based branding strategies to expand market reach and enhance the resilience of Puspazary MSMEs in this digital era.
High stability of faecal microbiome composition in guanidine thiocyanate solution at room temperature and robustness during colonoscopy

Field: Medicine (Health Sciences)

We read with interest the paper by Jalanka et al ,1 who examined the influence of bowel preparation on intestinal microbiota by using phylogenetic microarray and quantitative PCR analyses of frozen samples. Conventionally, faecal samples are frozen on dry ice or in a deep-freezer (at −80°C) immediately after collection, as done by Jalanka et al , because bacterial taxa can change appreciably within 15 min at room temperature (RT).2 However, immediate deep-freezing is often inconvenient in routine clinical practice, and we wondered whether simple storage of faecal samples at RT in test tubes containing 4 M guanidine thiocyanate solution would be equally effective. Guanidine thiocyanate is a general protein denaturant3 and inhibits bacterial growth.3–5 We collected faecal samples before and after colonoscopy, and divided each into two parts: one was stored frozen and the other at RT. Taxonomic compositions were determined by 16S ribosomal RNA sequence analysis, and the results in the two groups were compared. We also examined the stability of faecal microbiome composition, since Jalanka et al found that the intestinal microbiota is changed by whole-bowel irrigation, but …
Applications of Machine Learning Techniques in Genetic Circuit Design

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Construction of mathematical models to investigate genetic circuit design is a powerful technique in synthetic biology with real-world applications in biomanufacturing and biosensing. The challenge of building such models is to accurately discover flow of information in simple as well as complex biological systems. However, building synthetic biological models is often a time-consuming process with relatively low prediction accuracy for highly complex genetic circuits. The primary goal of this study was to investigate the utility of various machine learning (ML) techniques to accurately construct mathematical models for predicting gene expressions in genetic circuit designs. Specifically, classification and regressions models were built using Random Forrest (RF), Support Vector Machines (SVM), and Artificial Neural Networks (ANN). The obtained accuracy of the regression model using RF and ANN yielded R2 scores of 0.97 and 0.95, respectively, compared to the best score of 0.63 obtained in an earlier study. Furthermore, a classifier model was built using the green fluorescent protein (GFP) measurements obtained from the experiments conducted in this work. Biologists use GFP as an indicator of gene expression, enabling easy measurement of its protein level in the living cells. The measured GFP values were predicted with 100% accuracy by both RF and ANN classifier models while identifying various synthetic gene circuit patterns. The paper also highlights importance of the relevant data preparation techniques to ensure high accuracy is obtained by the utilized ML models.
An On-Station Analysis of Factors Affecting Growth Traits of Pure Red Maasai and Dorper Sheep Breeds under an Extensive Production System

Field: Agricultural and Biological Sciences (Life Sciences)

This comparative study aimed to evaluate genetic and environmental factors’ effects on the growth traits of lambs in Dorper and Red Maasai (RedM) sheep breeds. The data analyzed contained the following measurements: birth weight (Bwt), weaning weight (Wwt), yearling weight (Ywt), birth type (single or twins), and details on each lamb’s dam (dam ID and age) and sire. Except for the RedM, whose birth weight decreased with time, both breeds generally showed an increase in other growth weights across the study period, with yearly variations affecting both breeds. Additionally, analysis by a linear mixed model with restricted maximum likelihood (REML) showed that only breed as a factor significantly (p < 0.05) influenced birth weight; breed, sex, and birth type all significantly (p < 0.05) influenced weaning weight, whereas season, sex, and dam age significantly (p < 0.05) influenced yearling weight. The RedM breed outperformed the Dorper breed in post-weaning growth rate, demonstrating early resilience and adaptation to local environmental factors independent of maternal influence. Breed and non-genetic factors play a vital role in the growth of lambs, and the results of this study offer an opportunity for improved farm management under an extensive production system and selection for the conservation of the indigenous Red Maasai breed.