jimnoneill/paper-to-field-training huggingface dataset:
Law Enforcement of Dangerous Fishing Methods to the Conservation of Inland Fisheries Resources in Public Waters South Sumatera Province

Field: Environmental Science (Physical Sciences)

The inland fisheries resources in the public waters of South Sumatera Province are vital for the ecological balance, biodiversity, and socio-economic well-being of local communities. However, the rampant use of dangerous fishing methods poses a significant threat to these valuable resources. This study investigates the efficacy of law enforcement measures in curbing the practice of hazardous fishing methods and their impact on the conservation of inland fisheries resources. The research employs a multidisciplinary approach, combining legal analysis, ecological assessment, and community engagement strategies. Legal frameworks and regulations regarding fisheries management and conservation are scrutinized to identify gaps and weaknesses. Field surveys assess the prevalence and impact of dangerous fishing methods on inland fisheries resources. The study also examines the enforcement mechanisms, including the effectiveness of patrols, penalties, and community awareness programs.
Abstract 2769: Response to 5FU therapy in colorectal cancer is affected by EZH2-mediated BclX splicing

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Background and Aims: The chromatin modifier EZH2 is remarkably up-regulated in many cancer types including colon cancer. High levels of EZH2 have been correlated with tumor metastasis and regulation of tumor-initiating cell subpopulation. Since, DZNep, an EZH2 inhibitor, can inhibit the growth capability of colon cancer by inducing apoptosis; down-regulation of EZH2 seems to be a promising therapeutic approach. Our preliminary data showed that EZH2 levels were remarkably increased in blood samples from metastatic colorectal cancer patients who did not respond to the combination therapy with bevacizumab-irinotecan-5FU in comparison to patients who were responders and developed a stable disease. Many apoptosis-related proteins possess a dual function (pro- and anti-apoptotic) due to alternative splicing. Therefore we aimed to find possible apoptosis-associated EZH2 targets to explain these interesting findings. Methods: HCT116 colon cancer cells were used for DZNep and 5FU treatment and its efficiency was verified by Western blot analysis. In vivo splicing assay was performed using BclX minigene construct. The mRNA expression of EZH2, caspase 2, Death-associated protein kinase (DAPK) and BclX isoforms was assessed by quantitative real-time PCR in cells (BclX also in blood of patients) and normalized to the GAPDH. Cell viability was examined by Crystal Violet staining. Results: Western Blot for caspase 3 cleavage indicated increased apoptotic levels after DZNep treatment. Combined DZNep and 5FU treatment of cells led to a synergistic effect in reducing cell viability. DZNep treatment specifically promoted pro-apoptotic BclXs isoform, but did not affect the shift of pro-apoptotic isoforms of caspase 2 and DAPK. Using a BclX minigene transfection we confirmed this effect exogenously. The ratio BclXs/Xl was significantly altered by overexpression of different splicing factors such as ASF/SF2, Sam68, after DZnep treatment. Moreover, patients who did not respond to the combination therapy had the highest EZH2 and BclXl isoform levels. Conclusion: Our data indicate a new interesting link between epigenetic regulation and the splicing machinery. Detailed investigation of EZH2-mediated regulation of BclXs/Xl ratio could have the potential for prediction of 5FU-based therapy response in colon cancer patients. Citation Format: Natalya Benderska, Maria Gazouli, Gerasimos Aravantinos, Arndt Hartmann, Regine Schneider-Stock. Response to 5FU therapy in colorectal cancer is affected by EZH2-mediated BclX splicing. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 2769.
A microsatellite marker for studying the ecology and diversity of fungal endophytes (Epichloë spp.) in grasses

Field: Agricultural and Biological Sciences (Life Sciences)

Randomly amplified polymorphic DNA fingerprinting, which is based on PCR with arbitrary 10-nucleotide primers, were used to analyze genetic diversity among isolates of the endophytic ascomycete Epichloë typhina, which were collected at a single field site from a population of one of its hosts, the grass Bromus erectus. One of the polymorphic randomly amplified polymorphic DNA PCR products occurred in all isolates as single bands with different but closely related sizes. Two of the size variants of this product were cloned and sequenced, and they were found to represent the same DNA sequence, except for a stretch of tandem repeats of the trinucleotide AAG.TTC, which differed in size, consisting of 8 and 18 repeats, respectively. Tandem repeats of this type are called microsatellites. Oligonucleotides were synthesized corresponding to portions of the sequence flanking the microsatellite and were used for PCR amplification of the loci from the genomic DNAs of different Epichloë isolates. A single PCR product was found for most isolates, indicating that the sequence represented a single genetic locus. Five alleles that could clearly be distinguished in size were found in a population of 91 field isolates. PCR with (AAC)8 and (AAG)8 as primers yielded a number of amplified bands from genomic DNA of Epichloë isolates, indicating that these types of microsatellites occur frequently in the genome of this fungus. A survey of all fungal DNA sequences currently deposited in the DNA sequence databases of EMBL and GenBank revealed that microsatellites of different repeating units are widespread in fungi.(ABSTRACT TRUNCATED AT 250 WORDS)
Changes of trends in the size of the dental implants in recent years Part 1. The role of short implants in dental implantology The literature review.

Field: Dentistry (Health Sciences)

The requirements for osseointegration have been determined decades ago, among which was the appropriate size of the dental implants. In the last few years, in both - domestic and foreign literature- we can find more and more articles suggesting short and narrow dental implants as a treatment possibility. They may serve as an alternative to various bone grafting techniques and may replace the time demanding, more invasive and expensive horizontal and vertical bone augmentation procedures. Using short and narrow implants we can avoid interventions often accompanied by serious complications, such as bone distraction and inferior alveolar nerve transposition which pose greater risk for the patient. Our objective is a two-part review of the periodic literature in order to establish whether short and narrow dental implants can serve as a real alternative treatment modality.
What Drove the Carrington Event? An Analysis of Currents and Geospace Regions

Field: Earth and Planetary Sciences (Physical Sciences)

Abstract The 1859 Carrington event is the most intense geomagnetic storm in recorded history, and the literature provides numerous explanations for what drove the negative H perturbation on the Earth. There is debate on what dominated the event. Our analysis shows a combination of causes of similar orders of magnitude. Previous analyses generally rely upon the observed H perturbation at Colaba, India; historic newspaper reports; and empirical models. We expand the analysis using two Space Weather Modeling Framework simulations to examine what drove the event. We compute contributions from currents and geospace regions to the northward B field on Earth's surface, B N . We examine magnetospheric currents parallel and perpendicular to the local B field, ionospheric currents, and gap region field–aligned currents (FACs). We also evaluate contributions from the magnetosheath, near–Earth, and neutral sheet regions. A combination of currents and geospace regions significantly contribute to B N on the Earth's surface, changing as the storm evolves. At storm onset, magnetospheric currents and gap–region FACs dominate in the equatorial region. At auroral latitudes, gap–region FACs and ionospheric currents are the largest contributors. At storm peak, azimuthal magnetospheric currents and gap–region FACs dominate at equatorial latitudes. Gap–region FACs and ionospheric currents dominate in the auroral zone, down to mid‐latitudes. Both the magnetosheath and FACs contribute at storm peak, but are less significant than that from the near–Earth ring current. During recovery, the near–Earth ring current is the largest contributor at equatorial latitudes. Ionospheric currents and gap–region FACs dominate in the auroral zone.
Biology, distribution and diversity of cartilaginous fish species along the Lebanese coast, eastern Mediterranean

Field: Agricultural and Biological Sciences (Life Sciences)

The aim of this study is to contribute to a better knowledge of cartilaginous fish in the Lebanese coastal waters, Eastern Mediterranean. Emphasis was placed on various aspects of the distribution, diversity, biology and ecology of these species. In this study, a total of 314 specimens of cartilaginous fish were sampled. These specimens constituted of 25 cartilaginousfish species, 11 shark species and 14 batoid species. No chimaeras were recorded. The data was collected from two sources: (a) an experimental survey in the framework of the CIHEAM PESCA-Libano project and (b) periodic observation of fisheries and catches of hired fishermen. Spatiotemporal distribution was evaluated using the Catch Per Unit Effort of the experimental survey data. Spatiotemporal diversity was also estimated taking into account the total number of species caught in the survey and fisheries/fishermen data. Length-weight relationships for three sharks and five batoids were also presented for species of the combined data sources having more than 10 individuals. Finally, the biology and ecology of two commercially significant and exploited species were also presented as a first step in their fishery management andconservation.
Aligning assessment with long‐term learning

Field: Social Sciences (Social Sciences)

Assessment in higher education is commonly held to contribute to feedback to students on their learning and the certification of their achievement. This paper argues that this short‐term focus must be balanced against a longer‐term emphasis for learning‐oriented assessment to foster future learning after graduation. The paper proposes that students need to become assessors within the context of participation in practice, that is, the kinds of highly contextualised learning faced in life and work. It discusses the kinds of practices that are needed to refocus assessment within higher education courses to this end.
Genetics and Justice, Non-Ideal Theory and the Role of Patents: The Case of CRISPR-Cas9

Field: Arts and Humanities (Social Sciences)

Abstract There are ongoing concerns of social justice regarding inequalities in the distribution of access to potential genome editing technologies. Working within non-ideal theory, Colin Farrelly advances a justification for the use of patents to speed up the arrival of safe and effective interventions for all, including the socially disadvantaged. This paper argues that such success is less assured when one considers the actual functioning of patents and the practical implications of the patent system in the context of biotechnological innovations. I suggest that non-ideal theoretical approaches risk reverting back to a form of ideal theory if they simply refer to such real-world constraints — e.g. patents — but do not critically assess and fully examine how such constraints manifest themselves in practice. I highlight some considerations that would be important in order to develop and foster a more robust non-ideal approach to justice in biotechnological developments.
Remarks on the operator-valued interpolation for multivariable bounded analytic functions

Field: Mathematics (Physical Sciences)

We consider a domain D ⊂ C n defined by a uniform norm inequality sups ∥Δ λ (z)∥ < 1 involving a set Δ = (Δ λ ) λ of matrix-valued analytic functions Δ λ . The associated Schur interpolation class is then S = {F = F(z): sup ∥F(Z)∥ ≤ 1}, ∥Δ(Z)∥<1 where Z runs the commuting n-tuples of matrices. We characterize by positive-definiteness conditions the existence of the solutions F ∈ S of an operator-valued Nevanlinna-Pick type problem over D. Also, we describe the elements of S as fractional transforms F = a 22 + a 21 (I - Δa 11 ) -1 Δa 12 , with [a ij ] 2 i,j=1 unitary. The results are based on a representation technique due to J. Agler [1].
Stimulation Contractility Gradient of a Neuromuscular Choristoma Within the Sciatic Nerve: 2-Dimensional Operative Video

Field: Medicine (Health Sciences)

Abstract Neuromuscular choristoma (NMC) is a rare congenital nerve lesion that is classified by the presence of heterotopic muscle fibers intercalated within nerve fascicles. 1 The presence of NMC typically causes progressive neuropathy and bony/soft tissue undergrowth, often leading to a shortened atrophic limb. 2,3 The typical appearance of NMC on magnetic resonance imaging is an enlarged fusiform nerve that exhibits minimal gadolinium enhancement. 4 While there is increasing documentation of pathognomonic clinical and radiographic features for various diffuse fusiform peripheral nerve lesions, nerve biopsy is still occasionally required for some patients given the rarity of these diseases and progressive neuropathic features. The intraoperative appearance of NMC and its unique electrical stimulation properties are quite interesting. Intrafascicular replacement of nerve by skeletal muscle gives the nerve a red beefy color and causes the fascicles to contract with electrical stimulation. 5 In this video, we demonstrate the intraoperative appearance and contractile properties of NMC in a 60-yr-old woman with progressive sciatic neuropathy. Histologic and immunohistochemical studies identified a gradient of intralesional mature skeletal muscle within the NMC, with substantially fewer desmin-positive skeletal muscle fibers in the distal aspect. A gradient of contractility with intraoperative stimulation seemed to correlate with this pathology. These findings suggest that the lesional extent of NMC may not be clinically or grossly evident, reflecting a varying distribution of skeletal muscle within the affected nerve. The Mayo Clinic Institutional Review Board Office for Human Research Protection does not require approval for single participant case studies. The subject involved in this study was not identifiable and the general surgical consent form included permission for intraoperative photos and video.
Fibroblast growth factors as tissue repair and regeneration therapeutics

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Cell communication is central to the integration of cell function required for the development and homeostasis of multicellular animals. Proteins are an important currency of cell communication, acting locally (auto-, juxta-, or paracrine) or systemically (endocrine). The fibroblast growth factor (FGF) family contributes to the regulation of virtually all aspects of development and organogenesis, and after birth to tissue maintenance, as well as particular aspects of organism physiology. In the West oncology has been the focus of translation of FGF research, whereas in China and to an extent Japan a major focus has been to use FGFs in repair and regeneration settings. These differences have their roots in research history and aims. The Chinese drive into biotechnology and the delivery of engineered clinical grade FGFs by a major Chinese research group were important enablers in this respect. The Chinese language clinical literature is not widely accessible. To put this into context, we provide the essential molecular and functional background to the FGF communication system covering FGF ligands, the heparan sulfate and Klotho co-receptors and FGF receptor (FGFR) tyrosine kinases. We then summarise a selection of case reports that demonstrate the efficacy of engineered recombinant FGF ligands in treating a wide range of conditions that require tissue repair / regeneration. Alongside the functional reasons why application of exogenous FGF ligands does not lead to cancers are described. Together, this highlights that the FGF ligands represent a major opportunity for clinical translation, that has been largely overlooked in the West.
Nonlinear Interval Finite Elements for Beams

Field: Engineering (Physical Sciences)

The present study focuses on the development of Nonlinear Interval Finite Elements (NIFEM) for beam and frame problems. Three constitutive models have been used in the present study viz. bilinear, Ramberg-Osgood, and cubic models, to illustrate the development of Nonlinear Interval Finite Elements (NIFEM). The Interval Finite Element Method (IFEM) has been developed to handle load, material, and geometric uncertainties that are introduced in a form of interval numbers defined by their lower and upper bounds. However, the scope of the previous methods was limited to linear problems. The present work introduces an IFEM formulation for problems involving material nonlinearity under interval loads. The algorithm is based on the previously developed high accuracy interval solutions. An iterative method that generates successive approximations to the secant stiffness is introduced. Examples are presented to illustrate the behavior of the formulation. It is shown that bounding the response of non-linear structures for a large number of load combinations can be computed at a reasonable computational cost.
Prevalence of Escherichia Coli Among Urinary Tract Infections Patients (aged 0-70 years)Attending Hadejia General Hospital, Jigawa State-Nigeria

Field: Medicine (Health Sciences)

Urinary Tract Infections (UTIs) are one of the most common nosocomial infections after Respiratory Tract Infections (RTIs) worldwide. Nowadays it represents one of the most common diseases encountered in medical practice affecting people of all ages from the neonate to the geriatric age group. The aim of this research work was to find the prevalence of Escherichia Coli among Urinary Tract Infections patients (0-70 years) attending Hadejia General Hospital, Jigawa State-Nigeria between August and September, 2019. A total of One hundred (100) urine samples comprising of 42(42%) in female and 58(58%) in male were obtained from the patients with age ranged from 0-70 years and analyzed. Samples collected were cultured and incubated at 37C for 24 hours. Isolation and Identification of bacteria was done by standard laboratory procedures.
Assessment of Satisfaction Level of Edentulous Patients Rehabilitated with Implant-Supported Prostheses

Field: Dentistry (Health Sciences)

The treatments analyzed in this study were highly satisfactory with regard to functional and esthetic factors, resulting in an increase in self-esteem and quality of life. The psychological factor is a complex variable in patient satisfaction that directly influences quality of life. Considering the desires of patients in choosing the type of prosthesis is critical to treatment success.
EFFECT OF PROCESS VARIABILITY ON THE ECONOMIC VALUES OF AVERAGES CONTROL CHART PARAMETERS

Field: Decision Sciences (Social Sciences)

When the averages control chart is applied to monitor a manufacturing process, three parameters should be determined, sample size, sampling interval between successive samples and the control limit for the chart.This study shows how the effect of process variability caused by common and assignable causes on the values of averages control chart parameters.An example is presented and then based on this example, sensitivity analysis is performed to show the direction of control chart parameters changes in the presence of changes in the magnitude and frequency of process shift and the costs of discovering and correcting the causes of these shifts.
The capabilities of computers for language learning

Field: Computer Science (Physical Sciences)

Computer as a medium for language learning has been acknowledged by many educators in the past years. Using computers for language learning has proved not only interesting but also positive and stimulating for many language teachers and learners. The present paper tries to show the impact/s of computers in the field of second and foreign language learning. First of all, the advantages inherent in the use of computers for language learning will be discussed. Secondly, the technical preparation and requirements of language teachers and learners for the use of computers will be presented. And finally, the application of computers in the development of the four language skills will be analysed. We illustrate the computer capabilities to support different classroom activities, group-work and pair-work tasks; independent work; to stimulate student-centered learning and the individualization in language learning.
Nickel-Catalyzed Diastereodifferentiative Tandem Coupling of α,β-Enones, Norbornenes, and Organometallics

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTNickel-Catalyzed Diastereodifferentiative Tandem Coupling of α,β-Enones, Norbornenes, and OrganometallicsDong-Mei Cui, Hiroaki Yamamoto, Shin-ichi Ikeda, Keiichiro Hatano, and Yoshiro SatoView Author Information Faculty of Pharmaceutical Sciences, Nagoya City University, Tanabe-dori, Mizuho-ku, Nagoya 467, Japan Cite this: J. Org. Chem. 1998, 63, 8, 2782–2784Publication Date (Web):March 28, 1998Publication History Received16 December 1997Published online28 March 1998Published inissue 1 April 1998https://pubs.acs.org/doi/10.1021/jo972278ohttps://doi.org/10.1021/jo972278obrief-reportACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views332Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Chemical reactions,Hydrocarbons,Lipids,Mixtures,Nickel Get e-Alerts
Database-assisted frequency estimation for power system measurement

Field: Engineering (Physical Sciences)

In modern power transmission systems, monitoring of transient processes becomes more important. Analyzing a transient process is hard since the process is not only transforming from one steady state into another, but it also includes event-driven oscillations from LC-circuits within the net. The number of such oscillations is unknown and not constant. Furthermore, the oscillations can have a small amplitude. The knowledge of such oscillations can help understanding what happens where in the net. To estimate these oscillations, we present a signal processing method based on subspace estimation and history-based data ranking. It enables the estimation of an a-priori unknown number of oscillations and so the rank, although their amplitude might be small compared to dominating components.