jimnoneill/paper-to-field-training huggingface dataset:
Spontaneous Trance as a Possible Cause for Persistent Symptoms in the Medically Ill

Field: Medicine (Health Sciences)

A 45-year-old female underwent pericardiectomy for recurrent pericarditis. Four years later, persistent, unexplained chest pain was seen as a “conversion” symptom and treated with hypnosis and psychotherapy. Improvement was noted in narcotic dependence and level of function but not in the complaint of pain or disability status. The roles of the patient's emotional arousal and the physician's words in the setting of acute illness are explored as contributing factors in the genesis of the persistent pain. The concepts of spontaneous trance, posthypnotic suggestion, and conversion are reviewed in the context of this case.
Response to Comment on: Cohen et al. Effects of Gastric Bypass Surgery in Patients With Type 2 Diabetes and Only Mild Obesity. Diabetes Care 2012;35:1420–1428

Field: Medicine (Health Sciences)

We thank Dr. Kral for his thoughtful comments on our article regarding the use of Roux-en-Y gastric bypass surgery (RYGB) to treat type 2 diabetes (T2DM), and we would like to respond and add to his comments (1).

Although the 1991 National Institutes of Health (NIH) guidelines were thoughtfully constructed and have been highly valuable, we agree that they were not originally intended as stringent dictums governing bariatric surgery. The NIH itself posts the following concession atop their related website (http://consensus.nih.gov/1991/1991gisurgeryobesity084html.htm). “This statement is more than 5 years old and is provided solely for historical purposes… . Some of the material is likely to be out of date, and at worst simply wrong.”

Nevertheless, no updated NIH guidelines have since been rendered, and the 1991 recommendations have had enormous impact. American …
EXTRASKELETAL OSTEOGENIC SARCOMA

Field: Medicine (Health Sciences)

The authors report a case of extraskeletal osteogenic sarcoma originating from the upper paravertebral region of a 40‐year‐old Japanese male. The patient was treated by a combination of surgery, radiotherapy. and chemotherapy and died with widespread pulmonary metastases and local recurrence after total illness of more than 10 years. This case appears to be a unique example of long survival, extraordinary primary site and apparently benign histologic features of the original mass. Electron microscopic study of this tumor revealed irregularly shaped tumor cells with poorly differentiated intracellular organella and eventual deposition of apatite crystals in the intercellular fibrous structure. The world literature on extraskeletal osteogenic sarcoma is reviewed.
Additional file 3: of DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis

Field: Medicine (Health Sciences)

Figure S3. Ingenuity canonical pathways enriched in Slow-IPF SSEA4+ and SSEA4− cells compared to normal cells. SSEA4+ cells were sorted from normal and IPF lung fibroblast cultures. RNA was extracted from the sorted cells SSEA4+ and non-sorted SSEA4− cells and subject to RNA sequencing analysis as previously described (GSE103488). (A-B) Shown are Ingenuity canonical pathway analysis of Slow-IPF versus normal SSEA4+ cells (A) and Slow-IPF versus normal SSEA4− cells (B). Ingenuity was set to consider transcripts with an FPKM value ≥0.2 and a fold change ≥1.5 & ≤ − 1.5 (A) and FPKM value ≥1 and a fold change ≥1.5 & ≤ − 1.5 (B). Percentage depicts the proportion of transcripts from the transcriptomic analysis that are annotated in the Ingenuity canonical pathway. The percentage of transcripts that are downregulated or upregulated in each canonical pathway are depicted in green or red, respectively. (PDF 793 kb)
PHYTASE OF MOLDS USED IN ORIENTAL FOOD FERMENTATION

Field: Agricultural and Biological Sciences (Life Sciences)

ABSTRACT Molds commonly used in Oriental food fermentation have been examined for their ability to produce phytase. Except for Mucor dispersus NRRL 3103 and Actinomucor elegans NRRL 3104, all the other molds tested produced both extra‐ and intracellular phytase. The enzyme produced by Aspergillus oryzae NRRL 1988 was purified by acetone fractionation, gel filtration, and diethylaminoethyl‐cellulose chromatography. The phytase was successfully separated from an acid phosphatase, and a 44‐fold increase in specific activity was observed. The pH optimum of 5.3 characterizes the enzyme as an acid phosphohydrolase, and its maximum activity at 50°C suggests a relatively high thermostability. The enzyme is also fairly stable over a pH range 3.5‐7.8 at 25°C. The A. oryzae phytase is active with either phytic acid or glycerophosphate. as substrate, but it hydrolyzes phytic acid twice as fast as it does glycerophosphate. However, the enzyme is partially inhibited by high concentration of phytic acid. The Km value of A. oryzae phytase was estimated as 0.47 mM and V max was 11.9 μmoles P i per mg per mg protein.
The Association of Health Insurance with institutional delivery and access to skilled birth attendants: evidence from the Kenya Demographic and health survey 2008–09

Field: Health Professions (Health Sciences)

Healthcare financing through health insurance is gaining traction as developing countries strive to achieve universal health coverage and address the limited access to critical health services for specific populations including pregnant women and their children. However, these reforms are taking place despite limited evaluation of impact of health insurance on maternal health in developing countries including Kenya. In this study we evaluate the association of health insurance with access and utilization of obstetric delivery health services for pregnant women in Kenya.Nationally representative data from the Kenya Demographic and Health Survey 2008-09 was used in this study. 4082 pregnant women with outcomes of interest - Institutional delivery (Yes/No - delivery at hospital, dispensary, maternity home, and clinic) and access to skilled birth attendants (help by a nurse, doctor, or trained midwife at delivery) were selected from 8444 women ages 15-49 years. Linear and logistic regression, and propensity score adjustment are used to estimate the causal association of enrollment in insurance on obstetric health outcomes.Mothers with insurance are 23 percentage points (p < 0.01) more likely to deliver at an institution and 20 percentages points (p < 0.01) more likely have access to skilled birth attendants compared to those not insured. In addition mothers of lower socio-economic status benefit more from enrollment in insurance compared to mothers of higher socio-economic status. For both institutional delivery and access to skilled birth attendants, the average difference of the association of insurance enrollment compared to not enrolling for those of low SES is 23 percentage points (p < 0.01), and 6 percentage points (p < 0.01) for those of higher SES.Enrolling in health insurance is associated with increased access and utilization of obstetric delivery health services for pregnant women. Notably, those of lower socio-economic status seem to benefit the most from enrollment in insurance.
[Adenocarcinoma arising in congenital dilatation of the intrahepatic bile duct].

Field: Medicine (Health Sciences)

A multilocular lesion was found in the left lobe of the liver in a 70-year-old woman who had complained of jaundice, fever and tumor of epigastrium. There was a continuous and branching cystic lesion in the resected left lobe of the liver diffusely, and communication with the right hepatic duct and the extrahepatic duct was recognized. These cystic spaces were filled with bile and mucus. The inside of the wall was covered with columnar epithelium showing papillay proliferation with marked mucin production. Furthermore, adenocarcinoma was demonstrated in multifoci surrounded by hyperplastic and dysplastic epithelium. This case was diagnosed as congenital dilatation of the intrahepatic bile duct accompanying adenocarcinoma.
Research on Hierarchy Routing Secured Communication in WSN

Field: Computer Science (Physical Sciences)

Clustered sensor networks have been introduced into WSN,which have been shown to be increasingly beneficial in increasing system throughput,decreasing system delay,and conserving energy.However,the existing clustered scheme did not provide secured communication in cluster.Hence SSCRA is provided,which determine the size of a cluster and organize the cluster by service radius,use multi-hop routing in clusters.To realize secured communication,SSCRA use keys in Intra-Cluster and Inter-Cluster to guarantee the Encryption and authentication.Simulation experiments indicate that the new scheme can enhance the security in clustered sensor networks with comparatively lower energy consumption.
Devenir intracellulaire des vecteurs AAV dans les cellules dendritiques humaines et conséquences sur le transfert de gène

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Les vecteurs viraux dérivés du virus adéno-associé (AAV) apparaissent depuis deux décennies, comme des outils efficaces pour le transfert de gène in vivo. Cependant, malgré une faible immunogénicité et une absence de toxicité in vivo, leur optimisation requiert encore un effort important vers une meilleure compréhension de leur biologie et, en particulier, de leur interaction avec le système immunitaire. Au cours de ce travail de thèse, nous avons utilisé une méthode de sélection dirigée in vitro dans le but d’obtenir un variant de capside capable de transduire efficacement un type cellulaire non-permissif aux vecteurs AAV : les cellules dendritiques (DC). En effet, ces cellules jouent un rôle primordial dans l’établissement de la réponse immunitaire et, par conséquent, dans la persistance de l’expression du transgène in vivo. Cette technologie, très répandue dans la communauté AAV, a permis de sélectionner un variant de capside aux propriétés très intéressantes. La mutation sélectionnée, caractérisée in vitro comme induisant une instabilité de la capside, a permis d’identifier et de surmonter un point de blocage majeur dans le processus de transduction des DC par les vecteurs AAV consistant dans l’étape de décapsidation du génome du vecteur dans le noyau cellulaire. De manière intéressante, le variant obtenu exhibe un avantage en terme de transduction non seulement dans les DC mais aussi dans différents modèles de cellules primaires humaines (e.g. HUVEC) ou animales (OBC), peu ou pas permissive à l’AAV. De plus, des expériences de transfert de gène in vivo réalisées dans un modèle murin, indiquent que le variant sélectionné conduit à une meilleure expression du transgène, possiblement due à la mise en place d’un processus de tolérisation. Les propriétés remarquables de ce variant de capside, font de lui un candidat intéressant pour des applications médicales.
Sonic disruption of wood pulp fibres aided by hydrophobic cavitation nuclei

Field: Chemical Engineering (Physical Sciences)

Abstract For paper manufacturing and biofuel production, the controlled deformation of wood pulp is of interest, provided that the integrity of the fibre structure remains intact. Conventional ultrasonic pretreatment in the near-audible range has been observed to cause uncontrolled inertial cavitation damage in wood pulp fibres. To prevent internal damage, we proposed to subject wood pulp mixed with hydrophobic particles to 1-MHz short pulses above the nucleation threshold of the particles but below the Blake threshold, and to observe the interaction of pulsating cavities and wood pulp fibres assisted by high-speed photography. Our 1-MHz results showed the interaction of a collapsing bubble with a wood pulp fibre wall to form a liquid jet hitting the fibre, without apparent destruction of the structure, whilst our 20-kHz controls confirmed previously observed structural destruction. This study shows the feasibility of controlled wood fibre deformation at a high ultrasound frequency.
Ontogeny of mitochondrial calcium transport in spontaneously hypertensive (SHR) and WKY rats.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The current studies were designed to investigate calcium uptake by intestinal jejunal sacs as well as in intestinal mitochondria of spontaneously hypertensive rats and their genetically matched WKY control rats. Kinetics of jejunal calcium uptake by jejunal sacs of adult SHR and WKY rats showed a significant decrease in Vmax of calcium uptake in SHR (227 +/- 24 versus 423 +/- 22 nmol.g tissue-1.3 min-1) compared to WKY rats P less than 0.001. To explore the intracellular handling of calcium by the intestinal mitochondria, calcium uptake was characterized by intestinal mitochondria before (suckling and weanling periods) and after (adult period) development of hypertension. Calcium uptake by intestinal mitochondria was driven by ATP in the presence of succinate as a respiratory substrate. Calcium uptake was stimulated several fold by the presence of ATP compared to no ATP conditions. Maximal calcium uptake occurred between 15-30 min and was significantly greater in adult SHR and WKY rats compared to corresponding values in weanling and suckling rats. Maximal ATP dependent calcium uptake in adult, weanling and suckling WKY rats was significantly greater compared to corresponding mean values in each age group in SHR (P less than 0.001). Oligomycin (10 micrograms/mg protein) inhibited calcium uptake partially. Ruthenium red (0.25 microM), 1 mM sodium azide and 0.5 mM dinitrophenol inhibited calcium uptake by more than 80% in both SHR and WKY rats. Kinetic parameters for ATP stimulated calcium uptake at 10 s revealed a Vmax of 0.56 +/- 0.6, 3.46 +/- 0.23 and 3.95 +/- 0.52 nmol/mg protein/10 s in suckling, weanling and adult WKY rats.(ABSTRACT TRUNCATED AT 250 WORDS)
Phenotypic Differentiation between Weedy Rice Populations Associated with their Local Adaptation in Early-and Late-Season Rice Fields

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract Background: Temperatures and photoperiods can profoundly affect plant growth and development and play vital roles in the local adaptation of plant species. Weedy rice ( Oryza sativa f. spontanea ) is a conspecific weed of cultivated rice, and it was found in the same rice fields (sympatry) of early and late rice-cultivation seasons in Leizhou, Guangdong Province of China. Generally, the phenological conditions, such as temperature and photoperiod, are different in the two seasons. Therefore, the early- and late-season weedy rice populations in the same rice fields provide a perfect system for estimating sympatric divergence in plant species. The previous study had demonstrated considerable genetic divergence between the early- and late-season weedy rice populations. Here, we designed in situ common garden experiments to estimate the phenotypical differences between the two-season weedy rice populations and disclose the local adaptation in weedy rice populations associated with their ambient temperature and photoperiod. Results: Distinct air temperature and day length variation patterns were recognized between the early and late rice-cultivation seasons, based on the 10-year historical climate data. More stressful conditions, indicated by low air temperature and long day length, were found for weedy rice growth in the early seasons. Noticeably, significant differences in plant heights, the number of tillers, flowering time, and reproductive traits were detected between the two-season weedy rice populations according to the early-season common garden experiment. The early-season populations showed evident higher plant heights, more tillers, and earlier flowering time than the late-season populations. However, such differences were not detected in the late-season common garden experiment. In addition, evident local adaptation represented by the traits such as plant heights, flowering time, and reproductive traits was only detected in the early-season weedy rice populations. The principal component analysis also showed clear population clusters between the two-season populations using the phenotypical data. Conclusions: This study provided clear evidence of phenotypic differentiation between the sympatric early- and late-season weedy rice populations, probably associated with the local adaptation to their ambient temperature and photoperiod. Our findings also have potential roles in facilitating the design of strategies for effective weedy rice control practices.
Phenotypes Associated With Polycystic Ovary Syndrome Risk Variants

Field: Medicine (Health Sciences)

Abstract Context Polycystic ovary syndrome (PCOS) affects 10% of women of reproductive age. The genetic architecture of the disease is emerging, but there is little data exploring the effect of genetic risk on clinical presentation. Objective We hypothesized that genetic risk loci would influence measurable phenotypic traits. Methods This retrospective cohort study, conducted at an academic medical center, included women of European ancestry with PCOS (n = 404), as diagnosed by the National Institutes of Health criteria, and controls with regular menses and no hyperandrogenism (n = 408). We identified association between genetic risk variants and measured phenotypic traits using linear regression. Results In a combined analysis of cases and controls, 2 variants in loci containing the genes PRSS23 (P &lt; .001) and FSHB (P &lt; .001) were associated with gonadotropin levels. Two variants in loci containing NEIL2/GATA4 (P = .002) and CYP3 (P &lt; .001) were associated with androgen levels. Three variants in loci containing SHBG (P = .001), ZBTB16 (P &lt; .001), and CYP3 (P &lt; .001) were associated with ovarian morphology. One variant in the locus containing FTO (P = .001) was associated with hip circumference and was influenced by body mass index. Conclusion These results demonstrate that PCOS genetic risk variants may influence hormone levels and ovarian morphology and increase the risk of obesity. Increased genetic risk for PCOS appears to drive traits that underly the classical clinical presentation of PCOS.
UNESCO (in city schools), 1952

Field: Social Sciences (Social Sciences)

14 images. UNESCO (in city schools), 21 August 1952. James R. White (Senior at Los Angeles City College); Mrs. Pearson Carmean (Los Angeles); Milton H. Robertson (Veterans Foreign Wars post 1732 of South Gate); Mrs. Marguerite Eaton (North Hollywood); Mrs. Alma Shannon (North Hollywood); Mrs. Edith Weiss (conference of Jewish Women's Organization for UNESCO); L.V. Barker (Speaking for UNESCO); Mrs. Kenneth Spencer (first Vice President of State Parent Teachers Association for UNESCO); Reverend Keith Kanaja (Huntington Park Methodist Church); Milton H. Robertson; P.A. Horton; Mrs. Rosalind G. Bates.
Study of the hepatitis C virus NS3 helicase domain for application in a chemiluminescent immunoassay

Field: Medicine (Health Sciences)

The helicase domain of the hepatitis C virus (HCV) protein NS3 is a major immunodominant region that elicits a strong and specific immune response in the majority of HCV infections. Use of NS3 helicase-derived antigens in immunometric diagnostic assays is a mainstay in detection of HCV infections. However, thermal instability of NS3 helicase-related polypeptides is a common and severe issue hampering reproducibility, performances and shelf-life of HCV diagnostic immunoassays. In this work, a novel NS3 helicase-derived antigen is presented, with a sensible improvement in thermal stability and diagnostic performances over the currently used NS3 helicase-related antigens.
Migrant workers in Rochdale and Oldham

Field: Social Sciences (Social Sciences)

This research focuses on the needs and experiences of Central and Eastern European migrants living and working in Rochdale and Oldham. It was commissioned by Oldham Housing Investment Partnership, Oldham Metropolitan Borough Council, Oldham Rochdale Housing Market Renewal Pathfinder and Rochdale Metropolitan Borough Council in January 2008 and was conducted by a team of researchers from the Salford Housing & Urban Studies Unit (SHUSU) at the University of Salford.
Occupational safety in China: Safety climate and its influence on safety-related behavior

Field: Health Professions (Health Sciences)

The improvement of health and safety standards within the organizational context is an important issue of global concern. China’s occupational health and safety (OHS) has increasingly drawn national and international attention as it has not kept pace with its globalization of production and trade. The traditional approach to managing workplace safety in China has focused on the technical aspects of engineering systems and processes, and it has attributed the majority of workplace accidents and injuries to unsafe working conditions instead of the unsafe work practices of employees. However, there has been a fundamental shift in the safety management research carried out in many countries and across diverse industries, which aims to measure the impact of attitudinal, organizational, cultural, and social dimensions on occupational safety. This article examines the relationship between safety climate and safety-related behavior in the Chinese context and draws implications for the management of occupational safety in China.
ANALISA APLIKASI PEMBENAH TANAH ORGANIK DAN ANORGANIK TERHADAP PERTUMBUHAN DAN PRODUKSI KEDELAI (Glycine max L.)

Field: Agricultural and Biological Sciences (Life Sciences)

As a crucial aspect of domestic food security, soybean production in Indonesia depends on imported resources. The productivity of soybeans exhibits variability attributed to diverse factors, including climate change (particularly water availability), seed quality, soil fertility, and pest infestations. Soil conditions characterized by adequate water retention and nutrient availability are conducive to optimal soybean yield. Conversely, suboptimal soil conditions impede nutrient and water absorption, thereby limiting production potential. This research aimed to evaluate the vegetative and generative growth response of soybeans to soil amendments, specifically compost, zeolite, and dolomite. This research was conducted between August and November 2023 at the Seed Teaching Farm, Politeknik Negeri Lampung. The research was arranged in a randomized complete block design, with single-factor treatments applied to experimental units. Each treatment was replicated four times, and each replication consisted of three plant samples. The treatments that were used were control (P0), zeolite application at 5 t/ha (P1), dolomite application at 10 t/ha (P2), and compost application at 15 t/ha (P3). Analysis of variance was conducted, then followed by an HSD test at a significance level of 5% and correlation analysis. The results of this research indicate significant responses of soybean growth and yield to the applied soil amendments and among these, compost soil amendment emerges as the most suitable for enhancing soybean production.