jimnoneill/paper-to-field-training huggingface dataset:
Ubidecarenone Quantification in Food Supplements A new HPLC method

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Coenzyme Q10 has a powerful antioxidant effect because it protects cells against free radicals and plays an important role in metabolism. Although controversial some preliminary evidence suggests that Coenzyme Q10 can help prevent or treat treatment of diseases of the cardiovascular and musculoskeletal systems and liver problems. Age increase and medical conditions are associated with lower Coenzyme Q10. There are evidences that diet supplementation with supplements containing Coenzyme Q10 may be beneficial. This paper aims to develop an HPLC method for identifying and dosing Ubidecarenone in food supplements. Using this technique, several supplements containing varying Ubidecarenone, ranging from 76 to 103% of the stated amount per dosage form were tested. Keywords: Ubidecarenone, HPLC method, dietary supplements
Accurate Time Calculations of Falling Bodies in the Earth's Gravitational Field and Comparisons with Newton's Laws of Vertical Motion

Field: Physics and Astronomy (Physical Sciences)

The Earth is exposed annually to the fall of some meteorites and probably other celestial bodies which cause a potential danger to vital areas in several countries. Consequently, the accurate calculation of the falling time of such bodies is useful in order to take the necessary procedures for protecting these areas. In this paper, Newton’s law of general gravitation is applied to analyze the vertical motion in the Earth’s gravitational field. The falling time is obtained in exact form. The results are applied on several objects in real life.
Atorvastatin Inhibits Endothelial PAI-1-Mediated Monocyte Migration and Alleviates Radiation-Induced Enteropathy

Field: Medicine (Health Sciences)

Intestinal injury is observed in cancer patients after radiotherapy and in individuals exposed to radiation after a nuclear accident. Radiation disrupts normal vascular homeostasis in the gastrointestinal system by inducing endothelial damage and senescence. Despite advances in medical technology, the toxicity of radiation to healthy tissue remains an issue. To address this issue, we investigated the effect of atorvastatin, a commonly prescribed hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor of cholesterol synthesis, on radiation-induced enteropathy and inflammatory responses. We selected atorvastatin based on its pleiotropic anti-fibrotic and anti-inflammatory effects. We found that atorvastatin mitigated radiation-induced endothelial damage by regulating plasminogen activator inhibitor-1 (PAI-1) using human umbilical vein endothelial cells (HUVECs) and mouse model. PAI-1 secreted by HUVECs contributed to endothelial dysfunction and trans-endothelial monocyte migration after radiation exposure. We observed that PAI-1 production and secretion was inhibited by atorvastatin in irradiated HUVECs and radiation-induced enteropathy mouse model. More specifically, atorvastatin inhibited PAI-1 production following radiation through the JNK/c-Jun signaling pathway. Together, our findings suggest that atorvastatin alleviates radiation-induced enteropathy and supports the investigation of atorvastatin as a radio-mitigator in patients receiving radiotherapy.
Rooting of semi-hardwood blueberry mini-cuttings from different cultivars from the highbush and rabbiteye groups

Field: Agricultural and Biological Sciences (Life Sciences)

The objective of this work was to evaluate the rooting of semi-hardwood blueberry minicuttings, from different cultivars and groups, from the Highbush and Rabbiteye groups in the same culture medium. The experiment was carried out in an agricultural greenhouse in a commercial nursery whith semi-hardwood mini-cuttings were used. The work was conducted, with cuttings segmented into mini-cuttings with three gems and an average diameter of 1.5 mm. Subsequently, their bases were immersed, for 10 seconds, in a commercial solution of IBA, in the concentration of 2.000 mg.L-1, with a mixture of coarse-grained sand and commercial substrate in the proportion of 1:1 as a substrate. The Bifactorial experimental design used was in completely randomized blocks, with two groups (highbush and rabbiteye) and six cultivars (Georgiagem, Misty, O'Neal, Bluegem, Powderblue and Woodard), with four replications and ten cuttings per plot. The percentage of rooted cuttings and surviving cuttings, average number of roots and shoots per cuttings, length of the largest root and shoot, were evaluated. It was found that, in general, the rabbiteye group was superior when compared to the highbush group. Blueberry cultivars from the rabbiteye group when propagated by semi-hardwood cuttings, have greater rooting facility than cultivars from the highbush group. The rooting potential between the cultivars in blueberry studied was different, allow the formation of 95% of cuttings rooted in 90 days.
Interferon-b Pretreatment of Conventional and Plasmacytoid Human Dendritic Cells Enhances Their Activation by Influenza Virus

Field: Immunology and Microbiology (Life Sciences)

Influenza virus produces a protein, NS1, that inhibits infected cells from releasing type I interferon (IFN) and blocks maturation of conventional dendritic cells (DCs). As a result, influenza virus is a poor activator of both mouse and human DCs in vitro. However, in vivo a strong immune response to virus infection is generated in both species, suggesting that other factors may contribute to the maturation of DCs in vivo. It is likely that the environment in which a DC encounters a virus would contain multiple pro-inflammatory molecules, including type I IFN. Type I IFN is a critical component of the viral immune response that initiates an antiviral state in cells, primarily by triggering a broad transcriptional program that interferes with the ability of virus to establish infection in the cell. In this study, we have examined the activation profiles of both conventional and plasmacytoid dendritic cells (cDCs and pDCs) in response to an influenza virus infection in the context of a type I IFN-containing environment. We found that both cDCs and pDCs demonstrate a greater activation response to influenza virus when pre-exposed to IFN-b (IFN priming); although, the priming kinetics are different in these two cell types. This strongly suggests that type I IFN functions not only to reduce viral replication in these immune cells, but
Exploring the Antioxidant, Antimicrobial, Antidiabetic, and Anticancer Properties of Capsicum annuum L. (Samandağ Pepper): Biochemical and In Silico Insights

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Abstract Capsicum annuum L. species from the Samandağ district of Hatay/Turkey was used in our study. Phytochemical analysis of seed and fruit ethanol extracts of this plant was carried out by GC‐MS method. Total Antioxidant Status (TAS) and Total Oxidant Status (TOS) levels were determined to calculate the Oxidative Stress Index to determine antioxidant activity. MIC method was used to evaluate antimicrobial properties against pathogenic bacteria and fungi. Anticancer activity was determined by the XTT assay on breast (MCF‐7), lung (A549) and brain (C6) cancer cells and healthy fibroblast (WI‐38) cell lines. The effects of the extracts on acetylcholinesterase and α‐amylase activities were investigated. It was found that C. annuum fruit extract had a lower OSI value than the seed extract. Fruit and seed extracts showed antimicrobial activity on microorganisms at MIC values of 200 µg/mL. Molecular docking studies were conducted to analyze the antibacterial properties of plant active ingredients. These studies are chemical components that are determined to be more abundant in the plant extract. Thus, it aimed to evaluate the effects of active compounds on various bacterial species. The results revealed the potential antibacterial properties of plants and provided important data that these ingredients can be used in future treatment methods. The anticancer activity in all cancer cell lines was very high in both seed and fruit extracts with a selectivity index (SI) well above SI ≥ 3. Furthermore, no deleterious effect on healthy fibroblast (WI‐38) cells was observed. The extracts were found to decrease acetylcholinesterase activity but increase α‐amylase activity. As a result, these plant extracts were found to have anticholinergic potential.
Orbit misbehavior, isotropy discontinuity, and large isotypic components

Field: Mathematics (Physical Sciences)

Let $\mathbb{G}$ be a compact Hausdorff group acting on a compact Hausdorff space $X$, $α$ an irreducible $\mathbb{G}$-representation, and $C(X)$ the $C^*$-algebra of complex-valued continuous functions on $X$. We prove that the isotypic component $C(X)_α$ is finitely generated as a module over the invariant subalgebra $C(X/\mathbb{G})\subseteq C(X)$ precisely when the map sending $x\in X$ to the dimension of the space of vectors in $α$ invariant under the isotropy group $\mathbb{G}_x$ is locally constant. This (a) specializes back to an observation of De Commer-Yamashita equating the finite generation of all $C(X)_α$ with the Vietoris continuity of $x\mapsto \mathbb{G}_x$, and (b) recovers and extends Watatani's examples of infinite-index expectations resulting from non-free finite-group actions. We also show that the action of a compact group $\mathbb{G}$ on the maximal equivariant compactification on the disjoint union of its Lie-group quotients has tubes about all orbits precisely when $\mathbb{G}$ is Lie. This is the converse (via a canonical construction) of the well-known fact that actions of compact Lie groups on Tychonoff spaces admit tubes.
A Holistic Approach to Define Important Digital Skills for the Digital Society

Field: Social Sciences (Social Sciences)

Nowadays, transactions carried out with digital currencies are increasing. Modern societies are asked to respond to growing challenges related to the management of digital currencies in their daily lives. However, due to the lack of digital skills of users, the management of digital currencies hides risks. To the best of our knowledge, the originality of the current research lies in the act of combining the concept of digital skills with the use of digital currencies. After all, the use of digital currencies is constantly increasing, which means that citizens should familiarize themselves with their use, an element that makes this study valuable for digital societies. Digital skills effectively contribute to the development of digital societies because they increase the employment of citizens, facilitate access to information, and contribute to the social inclusion of individuals through digital communication, while also increasing efficiency and productivity in the workplace. Also, the government and banking institutions can more effectively sensitize citizens to digital skills for more effective use of digital currencies. In this way, tax payments will be facilitated, the use of e-wallets will be safer, and e-governance will be greatly promoted, while the quality of banking services will be improved. The methodology of this study was based on the Digital Competence Framework for Modern Societies (DigComp) and was applied through a questionnaire completed by 443 respondents. The main objective was to evaluate their digital skills from the perspective of digital currency use. The analysis of the responses was carried out by using Structural Equation Modeling (SEM). The most important result from this research reveals that users of digital currencies are significantly capable of developing communication to solve everyday problems. At the same time, users of digital currencies mostly detect digital threats and effectively manage fake news without being affected by them. However, users of digital currencies consider that security issues are important, but only for transactions and not for their supporting functions. The study concludes with suggestions for improving the experience of digital currency users through individual actions, thus having a positive impact on the state and banking institutions.
The connection between age, job control and sickness absences among Finnish food workers

Field: Health Professions (Health Sciences)

<b>Methods</b> The relationship between sickness absence and job control among industrial food workers of different ages (<it>n</it> &equals; 114) was studied. <b>Results</b> The number of absence spells, particularly short absence spells, was higher among younger workers, as expected. Using multivariate analysis, low job control was associated with an increased number of all absence spells (<it>P</it> < 0.02). <b>Conclusions</b> Job control may be an important factor in determining sickness absence among industrial workers.
If You See It Once, You Do Not Forget: Lhermitte-Duclos Disease

Field: Medicine (Health Sciences)

Lhermitte- Duclos disease (LDD) is a rare disorder of unknown pathogenesis, characterized by typical magnetic resonance (MR) findings. LDD can be associated with Cowden’s syndrome. So preoperative diagnosis is important for excluding the other associated tumors. Herein we present two cases of LDD and describe typical MR signal characteristics
Risk Assessment of Buildings due to Lightning Impulses: A Case Study at College of Science and Technology

Field: Engineering (Physical Sciences)

Lightning Impulse protection has become important aspect of any electrical installation due to its destructive impacts. Due to changing weather patterns the intensity of lightning has been increasing over the years. The impacts due to lightning impulses usually in domestic installations are destructive and often the electrical supply lines are damaged with service interruptions. College of Science and Technology (CST), is located at foothills of the Himalayas with sub-tropical climate and it experiences minimum of 12-16 lightning events per square kilometers per year. Therefore, the region experiences severe lightning events especially in the late spring, summer and early autumn seasons. In this research a risk assessment of building electrical installations is being analyzed to manage and mitigate the impacts due to lightning impulses by using IEEE 62305 standard to evaluate the risks. The risk assessment for case study location at College of Science and Technology, shows that the earth resistance is beyond the permissible limit as per national and international standards and lightning protection systems are being proposed at various locations in the campus. The current study does not include all the buildings of the CST campus but only selected buildings are assessed for impacts due to lightning impulses.
Research on Trojan Horse Hiding and Residence Technology According to Ghost Restoration

Field: Computer Science (Physical Sciences)

Ghost reduction system is widely used in the computer system restoration,this technology is easy to use while contains certain safety hidden trouble.This paper first describes Ghost image file format,and tells of its analytical process and principles.And on this basis,this paper draws out the Trojan hiding and residence technology of the Ghost image reduction system,and analyzes the realization of command line tool which can penetrate the Ghost image file.This tool reads and analyzes Ghost image file,and then writes in the back door to their files,thus to realize the Trojan horse hiding and residence.This paper finally puts forth how to prevent and detect the hiding and residing Trojan by this method,and thus to ensure the integrity and safety of restored system.
Environment Modeling for the Application in optimization-based Trajectory Planning

Field: Computer Science (Physical Sciences)

The paper at hand proposes an environment model for trajectory planning in structured environments. It is composed of a static and a dynamic environment model. The generated static potential field takes restrictions imposed by the static environment into account. The dynamic environment model is based on the physical interpretation of the required safety distance. By the use of an advanced obstacle trajectory prediction method, the safety distance is calculated in accordance to the predicted situation. As the safety distance affects the dynamic potential field, information provided by the obstacle trajectory prediction is directly considered in the ego vehicle trajectory planning process. On account of the predictive character of the developed environment potential field, simulation experiments demonstrate the feasibility and effectiveness of the proposed method.
Kierkegaard and Heidegger on the Concept of Guilt

Field: Arts and Humanities (Social Sciences)

Abstract This chapter considers the role of guilt in the thought of Kierkegaard and Heidegger. Kierkegaard contrasts the quantitative and external guilt which belongs to life in the crowd with the guilt that attaches to the infinite demand, which is qualitative and internal, and thus falls under the category of ‘totality’. This means, however, that guilt feeds of itself, as one comes to feel guilty for feeling guilty. Like Kierkegaard, Heidegger does not just consider guilt in relation to ordinary ethical and judicial norms, but also in relation to one’s existence, but this means that for Heidegger it becomes ontological, as we feel guilty even for existing. Thus, both Kierkegaard and Heidegger draw similar distinctions between forms of guilt, and make guilt in its fundamental form inescapable, but while Heidegger gives this a purely ontological basis, for Kierkegaard it takes an ethical form in relation to an infinite demand.
[Age and changes in the activity of several energy metabolism enzymes in the rabbit aorta].

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Age alterations in the activity of several key enzymes of glucose oxidative breakdown (hexokinase, glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase and cytochrome c oxidase) were studied in extracts from rabbit aorta. The hexokinase activity was measured also in mitochondrial fraction. The activity of all the enzymes studied in rabbit aorta (calculated either per 1 g of the tissue or per 1 mg of proteins) was the highest at the age from 1-2 weeks to 1 month. The minimal activity was observed in adult animals, which were 1-2 years old, In aorta of 3,5-4 years old rabbits an increase (per 1 g of the tissue) in the activity of the enzymes was observed.
Diplomacy in a Whirlpool: Hungary Between Nazi Germany and Soviet Russia. By Stephen D. Kertesz. [International Studies of the Committee on International Relations, University of Notre Dame.] (Notre Dame, Ind.: University of Notre Dame Press. 1953. Pp. xvi, 273. $4.75.)

Field: Social Sciences (Social Sciences)

Journal Article Diplomacy in a Whirlpool: Hungary Between Nazi Germany and Soviet Russia. By Stephen D. Kertesz. [International Studies of the Committee on International Relations, University of Notre Dame.] (Notre Dame, Ind.: University of Notre Dame Press. 1953. Pp. xvi, 273. $4.75.) Get access Diplomacy in a Whirlpool: Hungary Between Nazi Germany and Soviet Russia. By Kertesz Stephen D.. [International Studies of the Committee on International Relations, University of Notre Dame.] (Notre Dame, Ind.: University of Notre Dame Press. 1953. Pp. xvi, 273. $4.75.) C. E. Black C. E. Black Princeton University Search for other works by this author on: Oxford Academic Google Scholar The American Historical Review, Volume 59, Issue 3, April 1954, Pages 625–626, https://doi.org/10.1086/ahr/59.3.625 Published: 01 April 1954
Media agenda setting and elections: Voter involvement or alienation?

Field: Social Sciences (Social Sciences)

The article briefly reviews media agenda‐setting research findings from the past quarter century as well as findings from recent studies of the role of the "new" or nontraditional media in the 1992 U.S. presidential election. It is argued that past dominance of campaign agendas by politicians and the media is related to voter alienation, whereas evidence from the 1992 election of more grassroots agenda setting, with the help of nontraditional media such as television talk shows and town hall meetings, is coupled with evidence of greater voter interest and involvement in that election. Although the "new" media are not likely to solve all the problems of citizen alienation from politics and political manipulation of public and press, they do offer the possibility of more citizen involvement in elections and in politics more generally.
Sleep Deprivation in the Male With Chronic Obstructive Lung Disease

Field: Medicine (Health Sciences)

In recent years, the number of deaths from chronic obstructive lung disease has been increasing at an alarming rate in the United States. Three different reasons for this increase may be listed: (1) more people are surviving other diseases and living to the age at which chronic obstructive lung disease tends to kill; (2) the ability to recognize chronic obstructive lung disease has improved and, increasingly this disease is being identified on death certificates as the cause of deaths formerly attributed, in particular, to heart failure and pneumonia; and, (3) a true increase in the incidence and severity of this disease has occurred.
Longitudinal Study of the Effects of the Aprender a Convivir Program on Children's Social Competence

Field: Psychology (Social Sciences)

Social competence is considered one of the fundamental protection factors in the emergence of behavior problems since facilitates the social adjustment of subject and their psychological well-being. The investigation analyze the impact of a universal prevention program on three dimensions of social competence: cooperation, interaction and social independence. This is a quasi-experimental longitudinal study where the evolution of 91 children from 3 to 5 years of age is observed. Data analysis is carried out through a repeated-measures mixed ANOVA, where three factors were included: time (6 measurements), group and gender. Results show participant improvement on all the variables that were analyzed. The change becomes clearly evident in the experimental group after the first year of intervention, and this change continues over the next two years. There are small effects from the intervention program on social interaction (d = 0.20), moderate effects on social cooperation and social independence (d = 0.64 and d = 0.71, respectively) and large effects on the global measurement of social competence (d = 1.04).
How can a certification process focused on GAP provide better access to international markets for farmers?

Field: Agricultural and Biological Sciences (Life Sciences)

Sustainable standards are a tool to achieve GAP and certification/ verification is a way to demonstrate its compliancy. This project is based on gathering examples on how Good Agricultural Practices (GAP), when successfully applied, bring benefits to producers by using sustainable standards and how certification / verification process allow producers to have access to international markets. With this project lessons can be learnt on how the projects were conducted, why they were successful and what role could be played by the government. Report number CDI-13-014.