jimnoneill/paper-to-field-training huggingface dataset:
Modulating Effects of Urbanization and Age on Greenspace–Mortality Associations: A London Study Using Nighttime Light Data and Spatial Regression

Field: Environmental Science (Physical Sciences)

Urban greenspace exposure associates with improved health outcomes, particularly chronic disease mitigation. Based on the need to characterize spatial heterogeneity in the health benefits of urban greenspaces, this study quantified the association between greenspace accessibility and chronic disease mortality in London, while examining the modulating effects of urbanization and age. Utilizing nighttime light (NTL) data to define urbanization gradients and road-network analysis to measure greenspace accessibility, we applied geographically weighted regression (GWR) across 983 neighborhoods. Key findings reveal that over 60% of central London residents live within 300 m of greenspace, yet 20% fall short of WHO standards. Greenspace accessibility showed significant negative associations with standardized mortality ratios for both cancer (β = −0.0759) and respiratory diseases (β = −0.0358), and this relationship was more pronounced in highly urbanized areas and neighborhoods with higher working-age populations. Crucially, central urban zones show amplified effects: a 100 m accessibility improvement was associated with a potential reduction in cancer deaths of 1.9% and in respiratory disease deaths of 2.4% in high-sensitivity areas. Urbanization levels and working-age population proportions exert significantly stronger moderating effects on greenspace–respiratory disease relationships than on cancer outcomes. While observational, our findings provide spatially explicit evidence that the greenspace–mortality relationship is context-dependent. This underscores the need for precision in urban health planning, suggesting interventions should prioritize equitable greenspace coverage in highly urbanized cores and tailor functions to local demographics to optimize potential co-benefits. This study reframes understanding of greenspace health benefits, enhances spatial management precision, and offers models for healthy planning in global high-density cities.
Gambar Terukur Konteks Pelestarian Arsitektur Masjid Ki Buyut Trusmi Cirebon

Field: Arts and Humanities (Social Sciences)

Several heritage buildings dating back the ancient history of the Ki Buyut Trusmi Cirebon site have been renovated and new buildings added. This paper aims to examine measured drawings related to the absence of original architectural documents. The method consists of field observation, expression of cultural meaning and significant architectural elements, as well as measured drawing studies. The heritage of Hindu-Javanese architecture has historical significance as a tomb complex based on an 1898 map, which is still in great demand by pilgrims. The significance of Hindu-Javanese architecture is related to the position of the mosque in the tomb complex, the gate leading to the complex, the complex gate, the barrier wall, and the complex fence. The manifestation of Javanese architecture can be found in the building of the mosque with a three-tiered roof, connected to the two-level roof porch, and a place for ablution on the north side. The social meaning is related to the traditional events of procession, roof changing, Trusmian and the commemoration of the birth of the Prophet Muhammad SAW which has been preserved until now. Measured drawings of the situation of the mosque and the plans of the building reveal that the appearance of the complex is strictly limited to the main prayer rooms (signifying Javanese architecture), not yet accompanied by gates and barrier walls (indicating Hindu-Javanese architecture), for historical-archaeological relics. The measured image of the main door of the mosque (amounting to a height of 152 cm) shows the tradition of bowing respectfully when entering the prayer room (signifying Javanese Architecture). Hindu-Javanese architectural elements should also be recorded in measured drawings.
Prenatal diagnosis of a true fetal tetraploidy in direct and cultured chorionic villi.

Field: Medicine (Health Sciences)

Prenatal diagnosis of a true fetal tetraploidy in direct and cultured chorionic villi: Tetraploidy is characterized by four complete sets of chromosomes (4n= 92). Although it has been frequently reported in spontaneous abortions, tetraploidy is extremely rare in term pregnancy. Most of late surviving patients are diploid/tetraploid mosaics and present severe mental and physical impairment. Up to date, only five tetraploidies were ascertained in the prenatal stage in amniocytes and/or fetal blood lymphocytes. No one has been reported in chorionic villi probably because tetraploidy is generally considered in this tissue as a false positive result due to confined placental mosaicism (CPM) or placental culture artefacts. We report here on a case of tetraploidy detected in chorionic villi because of fetal cystic hygroma. We discuss the reliability of this diagnosis and propose guidelines in the follow-up of tetraploidies detected after chorionic villus sampling (CVS). Thus a misdiagnosis of this poor condition will be avoided at best and an appropriate genetic counseling will be given to the parents.
The Endovascular Management of a Neurofibromatosis Vasculopathy

Field: Medicine (Health Sciences)

We describe the management of a 30-year-old male with type I neurofibromatosis who required an above-knee amputation for bleeding, infection, swelling, and multiple severe joint instability. Postoperatively, he continued to bleed from the stump site. Angiography revealed multiple small distal bleeding aneurysms. Hemostasis was eventually achieved with standard microcoil embolization.
Importance of the Fermentation to Produce High-Quality Silage

Field: Agricultural and Biological Sciences (Life Sciences)

The objective of this chapter was to discuss the importance of the fermentation processes for silage making and how it affects the final quality of the silage. The preservation of the forage crops as silage is based on a fermentation process that lows the pH and preserves the nutritive value of the fresh crop. The main principle is the production of lactic acid by the lactic acid bacteria from the metabolism of the water-soluble carbohydrates in the fresh crop. However, different fermentations may occur into the silo environment and it depends on the availability of substrate, the microbial populations, the moisture content, and the buffering capacity of the crop at the ensiling. The fermentation is quite important in the ensiling process because it affects the nutritional quality of the silage and the animal performance. If the fermentation does not occur as recommended and the undesirable fermentations will take place, which will result in a total spoiled feed that is potentially risky for animals and human’s health. Well-fermented silage can be used in diets for ruminant animals without any risk for their health and without compromise the productive performance.
Liquidity and stock returns in order driven Asian markets : evidence from the Singapore stock market

Field: Economics, Econometrics and Finance (Social Sciences)

We study the relationship between liquidity and stock returns in the pure order driven Singapore stock exchange using the Restricted Seemingly Unrelated Regression (SURE). The aim of the study is to determine if a liquidity premium exists. The adjusted bid-ask spread and adjusted turnover are used as proxies for liquidity.
Tunable compound eye cameras

Field: Engineering (Physical Sciences)

We present design and realization concepts for thin compound eye cameras with enhanced optical functionality. The systems are based on facets with individually tunable focus lengths and viewing angles for scanning of the object space. The active lens elements are made of aluminum nitride (AlN)/nanocrystalline diamond (NCD) membranes. This material system allows slow thermally actuated elements with a large deformation range as well as fast piezoelectric elements with a smaller deformation range. Due to the extreme mechanical stability of these materials, we are able to realize microoptical components with optimum surface qualities as well as an excellent long-term stability. We use facets of microlenses with 1 mm in diameter and a tunable focusing power to compensate for the focus shift for different viewing angles during the scanning procedure. The beam deflection for scanning is realized either by laterally shifting spherical elements or by a tunable microprism with reduced aberrations. For both actuators we present a design,fabrication concept and first experimental results.
F.7 Chromosome 1p loss and 1q gain are highly prognostic and can inform WHO grading of meningioma

Field: Medicine (Health Sciences)

Background: The WHO grade of meningioma was updated in 2021 to include homozygous deletions of CDKN2A/B and TERT promotor mutations. Previous work including the recent cIMPACT-NOW statement have discussed the potential value of including chromosomal copy number alterations to help refine the current grading system. Methods: Chromosomal copy number profiles were inferred from from 1964 meningiomas using DNA methylation. Regularized Cox regresssion was used to identify CNAs independenly associated with post-surgical and post-RT PFS. Outcomes were stratified by WHO grade and novel CNAs to assess their potential value in WHO critiera. Results: Patients with WHO grade 1 tumours and chromosome 1p loss had similar outcomes to those with WHO grade 2 tumours (median PFS 5.83 [95% CI 4.36-Inf] vs 4.48 [4.09-5.18] years). Those with chromosome 1p loss and 1q gain had similar outcomes to those with WHO grade 3 cases regardless of initial grade (median PFS 2.23 [1.28-Inf] years WHO grade 1, 1.90 [1.23-2.25] years WHO grade 2, compared to 2.27 [1.68-3.05] years in WHO grade 3 cases overall). Conclusions: We advocate for chromosome 1p loss being added as a criterion for a CNS WHO grade of 2 meningioma and addition of 1q gain as a criterion for a CNS WHO grade of 3.
Wolf in a Sheep's Clothing: When do Complementors Face Competition with Platform Owners?

Field: Business, Management and Accounting (Social Sciences)

Digital platform ecosystems such as Apple iOS, SAP, and Google Android are transforming the nature of innovation and competition. Many firms find themselves as complementors to a dominant platform, at risk of experiencing competition with the platform owner. For example, platform owners release complements or integrate features into the platform thereby directly harming complementors’ businesses. While extant work focused on understanding how such competition affects complementors’ outcomes, it is yet to investigate when complementors face competition with platform owners in the first place. This paper presents an ongoing research project in which we seek to develop and test four hypotheses regarding this intriguing occurrence. We build a unique dataset that encompasses market entries by Google on Android and Apple on iOS and estimate a survival model in which market niches are metaphorically “at risk” of facing competition with platform owners.
Supplementary Table S3 from Tumor Tissue- versus Plasma-based Genotyping for Selection of Matched Therapy and Impact on Clinical Outcomes in Patients with Metastatic Breast Cancer

Field: Medicine (Health Sciences)

<p>Supplemental Table S3. Actionable mutations found in cfDNA and tumor tissue genotyping in 12 patients who went on to receive matched therapy after having both forms of testing.</p>
Copper(I)‐Assembled Pseudorotaxanes Bearing Bis(nitrile) Ligands: Selective Formation of Large Chelate Rings

Field: Chemistry (Physical Sciences)

Abstract The syntheses of two novel Cu I ‐bis(benzonitrile) complexes of the type [Cu(dCN n ) 2 ][PF 6 ] {where dCN n = NCPhO(CH 2 ) n OPhCN, n = 3, 4} are described. Both compounds have been characterized by X‐ray crystallography. To our surprise, and although the two complexes were quite similar, two very distinct structures were obtained. For the [Cu(dCN 4 ) 2 ][PF 6 ] complex, a tetrahedral geometry was observed whereas for [Cu(dCN 3 ) 2 ][PF 6 ], a polymeric assembly was formed. A further extension of this work involved the syntheses of two threaded species bearing the M30 macrocycle, Cu metal and a dCN n ligand. The formation of the desired complexes was confirmed by means of mass spectrometry as well as 1‐D and 2‐D 1 H NMR spectroscopy. Finally, the cyclic voltammograms of all 4 new species were recorded giving rise to redox potentials ranging from +0.88 to +1.25 V. These new threaded complexes are of particular interest since they can form the basis of novel rotaxane structures. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
LBNL-59605 Supersymmetry, Naturalness, and Signatures

Field: Physics and Astronomy (Physical Sciences)

Weak scale supersymmetry is often said to be fine-tuned, especially if the matter content is minimal. This is not true if there is a large A term for the top squarks. We present a systematic study on fine-tuning in minimal supersymmetric theories and identify low energy spectra that do not lead to severe fine-tuning. Characteristic features of these spectra are: a large A term for the top squarks, small top squark masses, moderately large tan β, and a small µ parameter. There are classes of theories leading to these features, which are discussed. In one class, which allows a complete elimination of fine-tuning, the Higgsinos are the lightest among all the superpartners of the standard model particles, leading to three nearly degenerate neutralino/chargino states. This gives interesting signals at the LHC — the dilepton invariant mass distribution has a very small endpoint and shows a particular shape determined by the Higgsino nature of the two lightest neutralinos. We demonstrate that these signals are indeed useful in realistic analyses by performing Monte Carlo simulations, including detector simulations and background estimations. We also present a method that allows the determination of all the relevant superparticle masses
Synthesis and Evaluation of (Pyridylmethylene)tetrahydronaphthalenes/-indanes and Structurally Modified Derivatives:  Potent and Selective Inhibitors of Aldosterone Synthase

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Elevated aldosterone levels are key effectors for the development and progression of congestive heart failure and myocardial fibrosis. Recently, we proposed inhibition of aldosterone synthase (CYP11B2) as an innovative strategy for the treatment of these diseases. In this study, the synthesis and biological evaluation of E- and Z-(pyridylmethylene)tetrahydronaphthalenes and -indanes (1a,b-38a) is described. The activity of the compounds was determined using human CYP11B2, and the selectivity was evaluated toward the human steroidogenic enzymes CYP11B1, CYP19, and CYP17. The biological results revealed a few rather selective inhibitors of CYP11B1, some compounds inhibiting both CYP11B1 and CYP11B2, and a large number of highly selective inhibitors of CYP11B2. The most active inhibitor was the 3-pyridyl compound 5a (IC(50) = 7 nM). The pyrimidyl-substituted derivative 28a was found to be the most selective CYP11B2 inhibitor (IC(50) = 27 nM) in this series, showing a 120-fold selectivity for CYP11B1 (IC(50) = 3179 nM). Molecular modeling, i.e., examination of the electronic and steric features of selected compounds and homology modeling and docking, was used to understand the structure-activity/-selectivity relationships.
Analysis and Stability of Orotic Acid in Milk

Field: Agricultural and Biological Sciences (Life Sciences)

A method based on HPLC and ion pairing techniques was used to determine the orotic acid concentrations in cows' milk.Average amounts were 69 to 74 mg/L.Orotic acid in milk was stable to heating but decreased during commercial yogurt fermentation.Correlations were made between the loss of orotic acid and the increase or decrease in pH during fermentation.
Gender Differences in Test Anxiety and Their Impact on Higher Education Students’ Academic Achievement

Field: Psychology (Social Sciences)

Test anxiety has detrimental effects on the academic performance of many university students. Moreover, female students usually report higher levels of test anxiety than do their male peers. The present study examined gender differences in test, trait, and math anxiety among university students, as well as differences in their academic achievement. Participants were 168 students from the University of Barcelona, all of whom completed measures of test anxiety, math anxiety, and trait anxiety. They were also asked about their expected level of anxiety when faced with four specific test situations: multiple-choice, open-question, oral presentation, and an exam involving calculations. At the end of the course in which they were enrolled, students were assessed through a multiple-choice and an open-question exam. Compared with their male counterparts, female students reported higher levels of test, math, and trait anxiety, as well as greater expected anxiety in three of the four test situations considered. However, females did not show lower academic achievement than male students in either the open-question or the multiple-choice exams. These results are discussed in terms of gender differences in socialization patterns and coping styles.
Cloning, nucleotide sequencing and bioinformatics study of NcGRA7, an immunogen from Neospora caninum

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Neospora caninum is an obligate intracellular parasitic protozoa and considered as causal agent of Neosporosis which infect wide variety of hosts. NcGRA7 is an immunodominant antigen recognized by sera from bovines, naturally infected by N. caninum, which is used as a powerful target for recombinant or DNA vaccine preparation against neosporosis. There is no study about identifying the molecular structure of Neospora caninum in Iran, so as first step, current study tried to identify NcGRA7 gene in this parasite in Iran. After extraction of total RNA from N. caninum tachyzoites, cDNA was synthesized and NcGRA7 gene was amplified using cDNA as template. Then the PCR product was cloned into pTZ57R/T vector and transformed into Escherichia coli (DH5α strain), and the resulted recombinant plasmid was submitted for sequencing, followed by bioinformatics analysis. The data obtained from sequencing of native NcGRA7 was recorded in GenBank. The deduced amino acid sequence of NcGRA7 in current study was compared with other N. caninum NcGRA7 sequences and showed some identities and differences. NcGRA7 gene of N. caninum was successfully cloned into the pTZ57R/T vector and recombination was confirmed by sequencing, colony PCR, and enzymatic digestion, making it ready expression of recombinant protein for further studies.
ENDOVASCULAR TREATMENT OF ABDOMINAL AORTIC ANEURYSM INVOLVING THE INTERNAL ILIAC ARTERIES USING THE EVAR METHOD - CLINICAL CASE

Field: Medicine (Health Sciences)

Introduction. Throughout the last decade, EVAR (EndoVascular Aneurism Repair), became the treatment of choice for treatment of abdominal aortic aneurism. Perioperative morbidity and mortality, as well as the inhospital stay are reduced due to the minimally invasive aspect of the procedure. In cases of hypogastric artery involvement in the aneurismatic process, these being seen in 20% of cases, EVAR limb extensions to the external iliac arteries are needed. Uni- or bilateral hypogastric artery embolisation prevent type II endoleak, due to back flow from the hypogastric artery. Case presentation. Hereby we report the first successful case of staged bilateral hypogastric artery embolisation and EVAR in the Republic of Moldova. A 72 y/o patient was diagnosed with Abdominal aortic aneurism involving bilateral common and hypogastric arteries. The diagnosis was confirmed by contrast CT. The decision was to preembolize the hypogastric arteries in two stages, one month from another, giving time for collateral bed development, for prevention of pelvic ischemia, which can be seen in up to 55% cases. The EVAR procedure underwent with bilateral limb extensions to the external iliac arteries. At angiographic control there were no signs of endoleaks, and no aneurism sac enhancement. At 3 month follow-up there were no endoleaks, and the aneurism sac was shrinked without contrast. Conclusions. Aortic aneurisms involving hypogastric arteries can be successfully treated by combining EVAR with hypogastric artery trunk embolisation, for prevention of type II endoleaks. Bilateral hypogastric artery involvement needs thorough individual planning, taking in consideration collateral bed anatomy.
Le dimensioni dell'intercomprensione. Dalla definizione alla valutazione delle compentenze

Field: Arts and Humanities (Social Sciences)

The Dimensions of Intercomprehension. From Definition to Skills Assessment. The studies on intercomprehension that have been produced in the last few years are numerous and analyse this discipline in all its facets. Nonetheless, the amount of research carried out to find a definition for the phenomenon has often highlighted the impossibility of fully defining it. The aim of this review is to analyse the attempts to describe intercomprehension through the studies that have been carried out on its definition, its use in teaching and, consequently, the assessment of learners.
Metastatic Pulmonary Calcification in a Patient with Adult T-Cell Leukemia/Lymphoma

Field: Medicine (Health Sciences)

HTLV-1 관련 ATLL은 다양한 임상양상을 나타낼 수 있으며 그 중 고칼슘혈증이 동반된 급성형의 경우 그 예후는 좋지 않을 수 있다. 저자는 HTLV-1 관련 ATLL 환자에서 고칼 슘혈증 및 전이성 석회화 폐결절이 진단된 환자에서 항암치료 변경투약 및 감염치료를 지속하였음에도 호전되지 않는 치명적인 증례를 경험하였기에 문헌고찰과 함께 이를 보고하는 바이다.
Expanding the case study: The narrative thread

Field: Social Sciences (Social Sciences)

A new research framework is described in this paper, termed 'the narrative thread'. It is a development of the case study, but argues that the paradigm of physical boundaries that has been used to define the case, can be shifted so that it is the phenomenon itself that defines the case, not where the case takes place. In addition, this framework has a number of attractive attributes, in that it is highly flexible, supports an inductive then a deductive approach, and gives formal guidance for both the incorporation of knowledge gained in literature reviews and the generation of theory.