jimnoneill/paper-to-field-training huggingface dataset:
Characterization of Virulence-Related Phenotypes in Candida Species of the CUG Clade

Field: Immunology and Microbiology (Life Sciences)

ABSTRACT Candida species cause a variety of mucosal and invasive infections and are, collectively, the most important human fungal pathogens in the developed world. The majority of these infections result from a few related species within the “CUG clade,” so named because they use a nonstandard translation for that codon. Some members of the CUG clade, such as Candida albicans , present significant clinical problems, whereas others, such as Candida ( Meyerozyma ) guilliermondii , are uncommon in patients. The differences in incidence rates are imperfectly correlated with virulence in animal models of infection, but comparative analyses that might provide an explanation for why some species are effective pathogens and others are not have been rare or incomplete. To better understand the phenotypic basis for these differences, we characterized eight CUG clade species— C. albicans , C. dubliniensis , C. tropicalis , C. parapsilosis , Clavispora lusitaniae , M. guilliermondii , Debaryomyces hansenii , and Lodderomyces elongisporus —for host-relevant phenotypes, including nutrient utilization, stress tolerance, morphogenesis, interactions with phagocytes, and biofilm formation. Two species deviated from expectations based on animal studies and human incidence. C. dubliniensis was quite robust, grouping in nearly all assays with the most virulent species, C. albicans and C. tropicalis , whereas C. parapsilosis was substantially less fit than might be expected from its clinical importance. These findings confirm the utility of in vitro measures of virulence and provide insight into the evolution of virulence in the CUG clade.
Spatial Distribution of Dynamic Characteristics of Fan Airflows and Their Impact on Thermal Comfort

Field: Engineering (Physical Sciences)

As one of the most widely used appliances in home and office scenarios over recent decades, electrical fans and their use in built environments have garnered considerable research interest. However, current methods are insufficient to reflect the overall characteristics of different types of fan equipment. This study conducted airflow field tests for six typical electrical fans and human comfort experiments across background temperature conditions of 26 °C, 28 °C, and 30 °C. The airflow test results showed the following: (1) for the mechanical airflow generated by fans, the mean airflow speed (MAS) had a strong negative correlation with turbulence intensity (Tu) and the power spectral index (β), which made Tu and β have a complementary distribution with airflow speed, meaning that areas with a higher airflow speed had lower dynamic characteristics; and (2) the form of the fan mainly affected the flow field distribution in the near-fan area (within 2 m), where tower fans and vaneless fans with elongated outlets had a mainstream airflow area that spread to about 0.2 m in width but 0.6 m in height at a distance of 0.25 m from the fan. The airflow speed distribution shape of axial-flow fans with circular outlets was circular on the test surface at the same position, with a radius of about 0.1–0.2 m. The human comfort experiment revealed that, at 28 °C, in the low-airflow-speed area (v < 1.5 m/s), the increased Tu and power spectral β of the airflow near the head and chest could reduce the thermal sensation vote (TSV). Additionally, this improvement slightly increased as the room temperature rose. When the airflow speed was high, the dynamic characteristics were generally low, and at this time, airflow speed played a leading role in reducing thermal sensation. The results of this paper have certain reference value for the improvement of comfortable dynamic characteristics and functional flow field design in subsequent fan product development.
High efficiency GaN power amplifier on C band

Field: Engineering (Physical Sciences)

Based on self-developed 0.25um GaN transistor technology, a broad band, high efficiency, high drain voltage RF power amplifier was fabricated on C band. This power amplifier was realized by internally matching, and the matching network consisted of LC networks and power divider. By improving the structure of the power divider, the efficiency of combination of the power divider and the bandwidth of the matching network was increased, and thus enhanced the efficiency and bandwidth of the whole circuit. The input and output impedance of the transistor model which was attained by the load-pull tool in ADS was matched to 50 ohm through the matching network. Then after HB and unite simulating, the final circuit was ensured. This amplifier using total 24mm gate-width transistor, was assembled in the high heat conductivity metal ceramic package QF136. And the result showed that under a condition of V ds =48V, V gs =-2.3V, with constant wave input, the output power of the amplifier was more than 155W, power gain was more than 10dB, and the PAE was more than 52%, with its peak reaches 55%.
Response of Vicia species to Ascochyta fabae and Uromyces viciae-fabae

Field: Agricultural and Biological Sciences (Life Sciences)

A collection of 267 accessions belonging to 61 Vicia species other than V. faba was screened under growth chamber conditions for response to Ascochyta fabae and Uromyces viciae-fabae, causal agents of ascochyta blight and faba bean rust, respectively. High resistance to both diseases was very frequently detected in Vicia spp. in contrast to the high susceptibility previously reported in most V. faba accessions. Most of the Vicia spp. accessions studied here were very resistant or even immune to A. fabae with only one per cent of the accessions allowing development of small lesions bearing pycnidia. High resistance or immunity to U. viciae-fabae was also frequently found in the collection, with only ten per cent of the accessions showing compatible interaction although with reduced disease severity. These findings reinforce the specificity of A. fabae and U. viciae-fabae and clarify the potential role of cultivated and wild Vicia spp. in the epidemiology of these faba bean diseases.
COMPLEX NETWORK ANALYSIS OF LITERARY AND SCIENTIFIC TEXTS

Field: Computer Science (Physical Sciences)

We present results from our quantitative study of statistical and network properties of literary and scientific texts written in two languages: English and Polish. We show that Polish texts are described by the Zipf law with the scaling exponent smaller than the one for the English language. We also show that the scientific texts are typically characterized by the rank-frequency plots with relatively short range of power-law behavior as compared to the literary texts. We then transform the texts into their word-adjacency network representations and find another difference between the languages. For the majority of the literary texts in both languages, the corresponding networks revealed the scale-free structure, while this was not always the case for the scientific texts. However, all the network representations of texts were hierarchical. We do not observe any qualitative and quantitative difference between the languages. However, if we look at other network statistics like the clustering coefficient and the average shortest path length, the English texts occur to possess more clustered structure than do the Polish ones. This result was attributed to differences in grammar of both languages, which was also indicated in the Zipf plots. All the texts, however, show network structure that differs from any of the Watts–Strögatz, the Barabási–Albert, and the Erdös–Rényi architectures.
MMPI-2 and Family Environment Differences between Bulimic and Nonbulimic Women and their Parents

Field: Psychology (Social Sciences)

We examined the relationships among psychological adjustment, perceptions of family environment, and the presence of bulimia. Twenty-nine bulimics and 33 nonbulimics completed the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) and Family Environment Scale (FES) parents of bulimics and nonbulimics were sent the FES to complete independently. Bulimics had higher scores than nonbulimics on MMPI-2 F, Hs, D, Hy, Pd, Pa, Pt, and Sc scales and lower scores on the L and K scales, with a clinically elevated mean configuration of 7-8-1. No differences in perceptions of family environment were found between bulimics and nonbulimics or between their fathers. Mothers of bulimics perceived more active-recreational orientation and less control than mothers of nonbulimics. For bulimics, perceived family cohesion was positively correlated with the Si scale of the MMPI-2. Finally, there was qualitatively less agreement on perceptions of family environment within bulimic than nonbulimic families. We discuss the clinical and research implications of these findings.
Front Cover

Field: Arts and Humanities (Social Sciences)

Next article FreeFront CoverPDFPDF PLUSFull Text Add to favoritesDownload CitationTrack CitationsPermissionsReprints Share onFacebookTwitterLinked InRedditEmailQR Code SectionsMoreFront cover: Carpet page, fol. 114r, Damascus Keter, made in Toledo, 1260, Jerusalem, NLI, 4 790 (photo: National Library of Israel). Next article DetailsFiguresReferencesCited by Gesta Volume 60, Number 2Fall 2021 Sponsored by the International Center of Medieval Art Article DOIhttps://doi.org/10.1086/717626 Views: 881Total views on this site © 2021 International Center of Medieval Art. All rights reserved.PDF download Crossref reports no articles citing this article.
Effect of induced shape anisotropy on magnetic properties of ferromagnetic cobalt nanocubes

Field: Materials Science (Physical Sciences)

We report on the synthesis of ferromagnetic cobalt nanocubes of various sizes using thermal pyrolysis method and the effect of shape anisotropy on the static and dynamic magnetic properties were studied. Shape anisotropy of approximately 10 % was introduced in nanocubes by making nanodiscs using a linear chain amine surfactant during synthesis process. It has been observed that, ferromagnetism persisted above room temperature and a sharp drop in magnetic moment at low temperatures in zero-field cooled magnetization may be associated with the spin disorder due to the effective anisotropy present in the system. Dynamic magnetic properties were studied using RF transverse susceptibility measurements at different temperatures and the singularities due to anisotropy fields were probed at low temperatures. Symmetrically located broad peaks are observed in the frozen state at the effective anisotropy fields and the peak structure is strongly affected by shape anisotropy and temperature. Irrespective of size the shape anisotropy gave rise to higher coercive fields and larger transverse susceptibility ratio at all temperatures. The role of shape anisotropy and the size of the particles on the observed magnetic behaviour were discussed.
A Biological Role for the Activation Peptides of Trypsinogen's?

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Conference Abstract| February 01 1984 A Biological Role for the Activation Peptides of Trypsinogen's? A. J. Cook; A. J. Cook 1Department of Surgery St. George's Hospital Medical School London Search for other works by this author on: This Site PubMed Google Scholar B. M. Austen; B. M. Austen 1Department of Surgery St. George's Hospital Medical School London Search for other works by this author on: This Site PubMed Google Scholar D. A. W. Grant; D. A. W. Grant 1Department of Surgery St. George's Hospital Medical School London Search for other works by this author on: This Site PubMed Google Scholar S. G. Cliffe; S. G. Cliffe 1Department of Surgery St. George's Hospital Medical School London Search for other works by this author on: This Site PubMed Google Scholar M. A. Hutton; M. A. Hutton 1Department of Surgery St. George's Hospital Medical School London Search for other works by this author on: This Site PubMed Google Scholar D. L. Wingate; D. L. Wingate 1Department of Surgery St. George's Hospital Medical School London Search for other works by this author on: This Site PubMed Google Scholar J. Hermon-Taylor J. Hermon-Taylor 1Department of Surgery St. George's Hospital Medical School London Search for other works by this author on: This Site PubMed Google Scholar Clin Sci (Lond) (1984) 66 (2): 13P. https://doi.org/10.1042/cs066013Pa_pt2 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation A. J. Cook, B. M. Austen, D. A. W. Grant, S. G. Cliffe, M. A. Hutton, D. L. Wingate, J. Hermon-Taylor; A Biological Role for the Activation Peptides of Trypsinogen's?. Clin Sci (Lond) 1 February 1984; 66 (2): 13P. doi: https://doi.org/10.1042/cs066013Pa_pt2 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu nav search search input Search input auto suggest search filter All ContentAll JournalsClinical Science Search Advanced Search This content is only available as a PDF. Article PDF first page preview Close Modal You do not currently have access to this content.
Sistem Penyusunan Laporan Keuangan Berdasarkan Invoice pada Pt. Abc

Field: Business, Management and Accounting (Social Sciences)

The purpose of collecting invoices at PT. ABC is to ensure that all transactions are well documented and to ensure the completeness of transaction data for the purposes of financial recording and reporting. The use of invoices in preparing financial reports is the main basis that must be used at PT. ABC. Invoices allow companies to monitor and manage transactions more effectively, as well as facilitate the accounting and financial management processes. This study was conducted using qualitative methods and using data collection techniques through interviews to understand in depth the process of preparing invoice-based financial reports at PT. ABC. This approach was chosen because it allows researchers to dig up information in detail and understand the context and dynamics in the financial reporting system. PT. ABC, a private company engaged in the field of CNG (Compressed Natural Gas) Supplier, requires an effective system to manage and organize financial data related to sales and expenditure transactions.
Two-Level Orthogonal Screening Designs With 24, 28, 32, and 36 Runs

Field: Mathematics (Physical Sciences)

The potential of two-level orthogonal designs to fit models with main effects and two-factor interaction effects is commonly assessed through the correlation between contrast vectors involving these effects. We study the complete catalog of nonisomorphic orthogonal two-level 24-run designs involving 3–23 factors and we identify the best few designs in terms of these correlations. By modifying an existing enumeration algorithm, we identify the best few 28-run designs involving 3–14 factors and the best few 36-run designs in 3–18 factors as well. Based on a complete catalog of 7570 designs with 28 runs and 27 factors, we also seek good 28-run designs with more than 14 factors. Finally, starting from a unique 31-factor design in 32 runs that minimizes the maximum correlation among the contrast vectors for main effects and two-factor interactions, we obtain 32-run designs that have low values for this correlation. To demonstrate the added value of our work, we provide a detailed comparison of our designs to the alternatives available in the literature. Supplementary materials for this article are available online.
Observation of intraseasonal oscillation of 64 day in the ionospheric sporadic E layers using Indian MST Radar, SABER / TIMED instrument and Ionosonde present at Gadanki(13.5 N,79.2 E)

Field: Physics and Astronomy (Physical Sciences)

15th MST Radar WorkshopSession M6: Middle atmosphere dynamics and structureMay 30 (Tue), Poster Session
Effect of sensory integration training on the cognition in patients with mild cognitive impairment

Field: Health Professions (Health Sciences)

Objective To investigate the effects of sensory integration training on aged patients(from 60 to 80-year-old)with mild cognitive impairment.Methods Forty-one patients with mild cognitive impairment were randomly divided into observed group(n=21) and control group(n=20),the observed group were treated with sensory integration training for 3 months,and the control group was not intervened.Before and after the training,Mini-Mental state examination(MMSE) and activity of daily living scale(ADL) were used to evaluate each patient′s cognitive function and daily living ability.Results The MMSE or ADL total scores after training in observed group were significantly higher or lower than those before training and which in control group(all P0.05).Conclusions The cognitive function and daily Living ability can be enhanced through sensory integration training in patients with mild cognitive impairment.
ARTIFICIAL BEACH NOURISHMENT ON THE GERMAN NORTH SEA COAST

Field: Environmental Science (Physical Sciences)

Several artificial beach nourishments were completed during the last twenty years on the German North Sea coast. Investigations made it possible to settle different problems connected with artificial beach nourishment and to gain additional information and experience. At present beach nourishments at Langeoog and Sylt will be realized in a way which is expected to bring the highest effectiveness. The hydrodynamic processes in connection with these beach nourishments and their change in shape will be subject to the paper.
Detection and therapeutic management of contagious ecthyma (ORF) in a kid

Field: Veterinary (Health Sciences)

A kid of age two and a half months was presented to Veterinary Clinical Complex (VCC), of Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, Haryana with history of skin lesions on fore head and nasal planum, along with alopecia and pruritis since one month. On physical examination, the lesion was observed to be dry and scabby in appearance. History from the animal owner revealed more number of similar cases of skin lesions in same age group of kids, suspecting it to be contagious. Skin scabs on molecular investigation revealed an Orf infection to the kid. The PCR product of 594bp size was generated. The kid was treated with broad spectrum antibiotic along with symptomatic and supportive treatment till complete clinical recovery. The animal owner was briefed about the zoonotic implications of the disease and was advised to take proper hygienic measures while handling the kids.
1085. Directed Evolution of AAV2 Leads to Improved Viral Function

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Adeno-associated viral (AAV) vectors are extremely safe and efficient gene delivery vehicles. However, numerous challenges in vector design remain, including neutralizing antibody responses, tissue transport, and infection of resistant cell types. In each case, the AAV capsid structure determines how the vector performs when presented with these barriers. Nature has evolved multiple AAV serotypes using mutagenesis and recombination, indicating a natural level of plasticity in viral structure and function. We have employed analogous techniques to rapidly generate a large random mutant AAV2 library and have selected for mutant AAV virions that display novel phenotypes. Specifically, we have selected the AAV2 library for infectious particles with altered heparin sulfate (HS) affinity and for the ability to evade an AAV2 immune response. Characterization of the mutants with both lower and higher affinity to heparin led to the location of novel point mutations on the capsid structure. Several of these mutations lie inside the capsid while two exposed mutations (K258E and S261F) lie in the canyon region. Furthermore, we have evolved vector variants that have greater than 100-fold improved resistance to serum that neutralizes wild type AAV2, yet retain AAV2 gene delivery efficiency. Analysis of the point mutations revealed one change on the surface of the 3-fold spike (N587I) and another change on the 2-fold dimple region (T716A) were critical to the enhanced resistance. Testing these vectors in animal studies may indicate that they could mediate gene delivery even in patients with pre-existing immunity. Finally, our libraries can be further analyzed to isolate mutants that surpass other barriers to successful gene delivery.
Indoor Activity Monitoring System Using an Accelerometer and Zigbee

Field: Health Professions (Health Sciences)

Physical activity assessment is useful for determining both physical and mental health. The measurement of activity has been performed by several techniques such as direct observations, subjective reports, metabolic measurements and portable physical activity monitors. Each type of technique has certain strengths and weaknesses. Recently, studies on portable physical activity monitors have been increasing and presented good assessment results. Upon consideration of the characteristics of the portable monitors such as being unconstrained and long-term monitoring, an indoor portable monitor was designed and developed. It measures three dimensional acceleration and transfers data by Zigbee protocol wirelessly. This system could help to assess daily activity without subject's consciousness.
Metadata matching 101: what is it and why do we need it?

Field: Computer Science (Physical Sciences)

https://doi.org/10.13003/aewi1cai At Crossref and ROR, we develop and run processes that match metadata at scale, creating relationships between millions of entities in the scholarly record. Over the last few years, we’ve spent a lot of time diving into details about metadata matching strategies, evaluation, and integration. It is quite possibly our favourite thing to talk and write about!
Oriented fragmentation of Escherichia coli sacculi by sonication

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Isolated murein sacculi of Escherichia coli PA3092 were physically ruptured by sonication. Electron microscopical analysis showed that the rupturing occurred preferentially prependicular to the long axis of the cell. The fragmentation of the sacculi increased with longer sonication times. It was found that the extent of cross-linkage was more affected by the sonication than was the average glycan chain length. These data confirm earlier observations and indicate that the glycan chains run predominantly perpendicular to the long axis of the cell. By contrast, the peptide cross-links are more dispersely oriented.
Analyzing heat units for different varieties of aromatic rice under various growing environments in Raipur condition

Field: Agricultural and Biological Sciences (Life Sciences)

Field experiment was carried out during Kharif season 2016 at Research and Instructional Farm of Indira Gandhi Agricultural University, Raipur (CG), India; to examine yield and heat unit requirements of three scented rice varieties as influenced by three different growing environments in factorial Randomized Block Design (RBD). Highest grain yield was recorded with Dubraj selection-1, as compared to Tarun selection-1 and Badshah bhog selection-1 on an average basis/overall basis under 27th June (D1) growing environment. With respect to heat units the cumulative growing degree days was found highest for Dubraj selection-1(2447) and Tarun selection-1 (2447) followed by Badshah bhog selection-1(2427) under 27th June growing environments (D1). Maximum growing degree days were observed in early sown crop D1 growing environments (27th June) as compared to late sown crop under D2 and D3 growing environment (12th July and 27th July). Similar results were found in the case of accumulated photo thermal units and helio thermal units also. Radiation use efficiency and HUE in D1 (27th June) growing environment might be due to better conversion of light in to dry matter, better yield component and harvest index in D1 (27th June) growing environment as compared to 12th July (D2) and 27th July (D3) growing environments.