jimnoneill/paper-to-field-training huggingface dataset:
Policies Governing Educational Objectives in Professor Motahari’s Epistemology and its Application in the Islamic Republic of Iran

Field: Arts and Humanities (Social Sciences)

Education and, consequently, trying to determine and explain the policies governing the objectives of the Islamic education is as old as Islam’s 1400 -year-old life. But these objectives in Imami Shiism have not been derived from Shiite scholars’ opinions because Shiites have been away from government and political power. Therefore, written works based on policies governing educational objectives from the epistemology of thinkers such as Professor Motahari in order to apply them in the Islamic Republic of Iran are not available. The present research after explaining the basics of Professor Motahari’s epistemology answers this fundamental question: What are the policies governing educational objectives in Professor Motahari’s epistemology? And how should it be applied in the Islamic Republic of Iran? (Question) The present writing assumes that policies like promoting spirituality, self improvement and developing creativity can be perceived from the foundations of Professor Motahari’s epistemology, policies which can dominate educational objectives. (Hypothesis) The aim is to present the policies governing educational objectives in Professor Motahari’s epistemology. (Objective) Data collection for the present research was done through library research. Then, data were evaluated based on description and analysis and using analytic-inferential method. (Methodology) Presenting the fourteen policies derived from Professor Motahari’s epistemology is new. (Finding)
[Method for the determination of the hematocrit of organs in vivo].

Field: Medicine (Health Sciences)

A method, based on the almost simuitaneous labeling of the plasma with Cl/sub 3/Cr/sup 51/ and of the red blood cells with Na/sub 2/Cr/sup 51/O/sub 4/, is described, by which the hematocrit can be measured in vivo. The patient's plasma is labeled, and the radioactivity is then almost simultaneously measured in vivo over the organ considered, e.g., the heart; the plasma radioactivity is measured in a sample of blood taken from a vein. The same procedure is then repeated considering the radioactivity of the red blood cells. By applying a formula, the hematocrit of the examined organ can then be calculated. The results of measurements of the cardiac hematocrit were fairly satisfactory as compared with measurements of the venous hematocrit and showed that two factors are of fundamental importance in order to obtain accurate measurements. Highly sensitive counters must be used and relatively large doses of isotope must be employed. Unless these conditions are observed, results will be unsatisfactory on account of the high statistical error. (auth)
Lancemaside A Isolated from the Root of Codonopsis lanceolata Inhibits Ovarian Cancer Cell Invasion via the Reactive Oxygen Species (ROS)-Mediated p38 Pathway

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Codonopsis lanceolata roots have been widely used in Korean cuisine and traditional medicine. This study aimed to investigate the antimetastatic effects of lancemaside A, a major triterpenoid saponin, isolated from the roots of C. lanceolata, in human ovarian cancer cells. Lancemaside A significantly suppressed the migration and invasion and the expression of matrix metalloproteinases (MMPs)-2 and -9 in ovarian cancer A2780 and SKOV3 cells. Treatment with lancemaside A generated reactive oxygen species (ROS) in ovarian cancer cells. However, treatment with anti-oxidant N-acetyl-L-cysteine (NAC) significantly negated the anti-invasive activity of lancemaside A. Additionally, lancemaside A activated p38 MAP kinase, which is mediated by ROS generation. This is the first study, to our knowledge, to reveal that lancemaside A isolated from the roots of C. lanceolata exerts antimetastatic activity through inhibition of MMP expression and cancer cell invasion via activation of the ROS-mediated p38 pathway.
Comparison of the effects of pentobarbital sodium and chloral hydrate anesthesia on post-ischemic damage in an experimental model of focal cerebral ischemia

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Introduction: Anesthetic agents, blood pressure, arterial pH and blood gases have been found to influence on the pathophysiology of experimental stroke. However, there are very few studies on the effects of anesthetic agents in the animal models of cerebral ischemia. Therefore, in this study, we compared the effects of chloral hydrate and pentobarbital anesthesia on the infarct size, motor neurological dysfunctions and physiological parameters in a transient model of focal cerebral ischemia. Methods: Twenty-four male Sprague-Dawley rats were divided into 2 groups and received either chloral hydrate (400 mg/kg, n=10) or pentobarbital sodium (60 mg/kg i.p., n=14) by intra-peritoneal injection. Temporary focal cerebral ischemia was induced by 90 min middle cerebral artery occlusion (MCAO), followed by 23 h reperfusion. Physiological parameters were measured before and after ischemia. Cortical and striatal infarct volumes and motor dysfunctions were determined 24 h after MCAO. Results: Cortical and striatal infarct volume in pentobarbital sodium anesthetized rats were 84 ± 8 and 26 ± 2 mm 3 , which were significantly lower than chloral hydrate group (208 ± 10, 62 ± 2 mm 3 , respectively, P < 0.001). Moreover, neurological motor dysfunction was significantly lower in pentobarbital sodium anesthetized in comparison with chloral hydrate group (P < 0.01). Physiological values were similar between 2 groups, except that the mean arterial pressure was significantly higher in the pentobarbital group compared with the chloral hydrate group (P < 0.05). Conclusion: The findings of this study indicate that chloral hydrate anesthesia causes higher brain injury and motor neurological deficits compared with pentobarbital sodium anesthesia in a temporary model of focal cerebral ischemia. Thus, the effects of anesthetic agents must be considered in experimental cerebral ischemia studies.
Functional and Ethical Considerations of Developing a Therapeutic Cure for HIV Using CRISPR

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Introduction to CRISPR and Human Viral Treatment The breakthrough of clustered regularly interspaced short palindromic repeats/CRISPR-associated protein 9 (CRISPR/Cas9) as a gene editing tool has revolutionized genetic manipulation. Initially discovered as a component of the bacterial adaptive immune system used to neutralize foreign DNA1, CRISPR was subsequently re-engineered to target the genome of eukaryotes, including human cell lines2-4. Recent developments are evolving the CRISPR/Cas9 system into an adaptable and precise tool for genetic engineering. It uses a guide RNA (gRNA), complementary to a target sequence, that leads the associated Cas9 nuclease to the gene of interest and induces DNA cleavage. In addition to the gRNA, a protospacer adjacent motif (PAM) nucleotide sequence is required to immediately follow the target sequence. This sequence is typically the trinucleotide NGG, which is required for Cas9 to initiate a double strand break in the DNA, which can be repaired by either non-homologous end joining (NHEJ) or homologous recombination (HR) (Figure 1). These cuts and subsequent repairs allow for the knockout of specific genes, or the insertion of foreign sequences. More recently, CRISPR has been used to target a variety of human viruses5, including Epstein-Barr virus6, Zika virus7, and most notably, Human Immunodeficiency Virus (HIV)8,9. Although the CRISPR/Cas9 gene editing system has demonstrated the potential to provide a cure for HIV, several limitations have sparked controversy in regard to its therapeutic value. The inconsistent fidelity and potential deleterious effects of CRISPR, as well as unanswered ethical concerns, call for further research in this field. In this article, we highlight recent advancements of the CRISPR system that may be applicable to HIV treatment, and ethical considerations that must be discussed in order to implement these techniques (Figure 2).
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Sella Cacatoria: A Study of the Potty in Archaic and Classical Athens

Field: Arts and Humanities (Social Sciences)

This article provides a detailed publication of an early black-figure infant/child seat, or potty, found in the Athenian Agora, including a series of brilliant watercolors by Piet de Jong. Later red-figure representationsshow such vessels in use. The potty is attributed to the Gorgon Painter, and the chronological range of such vessels is reviewed by gathering earlier and later examples of the form, both those preserved in the archaeological record and those known through iconography. Finally, the authors suggest that the term λ´ασανoν was used in antiquity to refer to such highchairs-cum-chamber pots.
Functions of mutant Axin gene in C6 glioma cell line

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Purpose To investigate the effects of mutant Axin gene in C6 glioma cells and to find whether this point mutation is related to the pathogenesis of glioma. Methods The proliferative ability of transfected cells was examined by MTT assay, cell growth curve and colony formation assay. The change of cell cycle was analyzed by flow cytometry (FCM). Immunostaining was used to detect the expression of Ki-67 and cyclin D1 in C6 cells and transfected cells. Results In comparison with the cells transfected with empty vector,the growing speed and colony formation ability of the cells transfected with wild Axin gene and mutant Axin gene were decreased significantly; The percentages of C6, C6-vector, C6-vector-Axin and C6-vector-Axin806 cells in S phase were 27.2%, 24.8%, 18.9% and 18.5% respectively; The expression of Ki-67 and cyclin D1 decreased as well. Conclusions The mutant Axin gene can inhibit cell proliferation in C6 cells, meanwhile wild Axin gene has the same function, but there is no significant difference between this two groups. This point mutation may not be a key factor in the pathogenesis of glioma.
Explaining The Causal Relationship Between Female Labor Force Participation And Its Determinants In Turkey

Field: Economics, Econometrics and Finance (Social Sciences)

Despite female labor force participation rate (FLFPR) has steadily increased from \n2005 onwards in Turkey, Turkey is still one of the countries having the lowest FLFPRs \nin the international arena. Furthermore, the labor force participation rate varies \nsubstantially by gender in our country. As is known to all, providing high level of \neconomic development in a country can be possible on the condition that high quality of \nhuman capital is utilized, gender inequality is eliminated and employment rate is kept \nup at a high level. Therefore, the objective of this thesis is to present the main barriers \npreventing women from the labor market in Turkey. This study also aims to draw \nattention to the reasons behind the labor supply barriers of women from the causal \nperspective. For this purpose, the impacts of the determinants have been estimated using \nthe data from Household Budget Surveys for the period of 2013-2015 via econometric \nanalyses such as Probit, GSEM, and Mediation. This thesis is unique \nin terms of employed analyses (GSEM & Mediation) which have not taken place \nin explaining FLFP either locally or globally. On the one hand, the results of this \nthesis have been consistent with the findings which were specified both \ntheoretically and empirically in the previous studies. On the other hand, this thesis is \ndiffered from the previous ones by testing the hypothesis such that “Turkish \nwomen participate in the labor market mostly by considering their opportunity costs \nfor non-market activities.” In conclusion, education has been found the key factor \naffecting women’s participation since the opportunity costs for \nnon-market activities are mostly determined by the education levels of women. \nAdditionally, marital status, fertility, age, household income, household expenditure, \nasset ownership, and if married, spouse employment status are the other important \nfactors affecting the women’s participation decisions in Turkey.
IDDF2023-ABS-0158 Evidence based perspectives for the benefits of lactobacillus rhamnosus GG and lactobacillus reuteri in gastroenterology practice – the indian consensus

Field: Medicine (Health Sciences)

Background

To formulate a consensus statement for the utilization of Lactobacillus Rhamnosus GG (LG) and Lactobacillus Reuteri (LR) based on contemporary evidence and the real-world experiences

Methods

A series of nationwide, collaborative educational initiatives was convened by leading clinicians at the forefront of the gastroenterology (CARE Study group) practice (n=99). The cumulative clinical experience was approximately 2500-man-years, who rated their level of agreement for 11 questions with each item on a 5-point Likert scale. The consensus was pre-defined if the weighted mean score > 100. GraphPad 9.5.1 and ANOVA were used for statistical analysis.

Results

The highest agreement score in the decreasing rank order (of weighted mean score), was that; LG has the potential to modulate the antibiotic-induced changes in the gut microbiota (122.9), LG is a useful tool in the expanding therapeutic armamentarium to address the unmet medical need in IBS (121.4), LR effective competitor of pathogens at the receptor site (118.6), LG is efficacious to address parameters to treat diarrhoea (115.3), mechanistic insights for LG are evolving to address its potential role in IBD (109.4), LG has an adjunctive role in the management of IBD (105.6) (IDDF2023-ABS-0158 Table 1). The adjusted mean response scores (±SD, 95% CI) for consensus were for, agree (77±16, 95% CI 66 to 88) followed by strongly agree (16±15, 95% CI 6 to 26), neither agree nor disagree (18±14, 95% CI 8.3 to 27), disagree (-6.4±8.7, 95% CI -12 to -0.58) (IDDF2023-ABS-0158 Figure 1)

Conclusions

We observed a high preference for the Lactobacillus Rhamnosus GG and Lactobacillus Reuteri for varied gastrointestinal conditions, which is in concurrence with contemporary evidence.
The Phanerozoic Evolution of the South-Tethys Domain from Morocco to Iran - Vertical Movements and Main Geodynamic Events

Field: Earth and Planetary Sciences (Physical Sciences)

With the aim of giving an integrated tectonic scenario for the Northern African and Arabian plates, we revisit six key areas, namely, the Anti-Atlas Belt (Morocco), the Bechar Basin (west Algeria), the Hassi R’Mel High (central Algeria), the Talemezane Arch (south Tunisia), the Western Desert (Egypt), and the High Zagros Belt (Iran). Below the so-called “Hercynian unconformity,” which is in reality a highly composite discontinuity, surface and subsurface data display a well-known arch-and-basin geometry, with basement highs and intervening Paleozoic basins. We show that this major feature results mainly from a Late Devonian event and can no longer be interpreted as a far effect of the Variscan Orogeny. From the Jurassic, Pangea breakup has been diachronic and the Alpine-Tethys propagated through the development of two branches which will finally connect at the end of Jurassic times, achieving the development of Africa northern plate boundary. By the Late Cretaceous, convergence between Africa and Eurasia led to the progressive closure of the Tethys realm. Two major geodynamic events appear synchronous and occured during the Campanian-Santonian and the Middle-Late Eocene. These two synchronous events coincides either with a change in plate kinematics or with a period of strong lithospheric coupling.
The impact of characteristics of intra-organizational environment on entrepreneurial marketing intensity and performance in Egypt

Field: Business, Management and Accounting (Social Sciences)

Purpose The purpose of this paper is to contribute to the entrepreneurial marketing (EM) paradigm by empirically investigating the relationship between intra-organizational environment, EM intensity (EMI) and organizational performance in an emerging market context. Specifically, the paper identifies the elements of the intra-organizational environment that enhances EMI and also examines the impact of EMI on organizational performance. Design/methodology/approach The data were collected from large-sized companies in Egypt. Data were analyzed by using path analysis on Smart-PLS. Findings The findings suggest that the characteristics of the intra-organizational environment that support developing and increasing EMI in large-sized companies in emerging markets are cooperative competency, deep locus of planning and institutional support. Also, it was found that the long planning horizon hinders EMI. Finally, it was found that EMI is positively related to organizational performance and competitive advantage. Practical implications The study provides guidelines for managers of large-sized organizations, especially in emerging economies, on how to develop the intra-organizational environment to enhance EMI. Originality/value The study of EMI received little or no attention in previous research. Also, there is a paucity of empirical research on the impact of the intra-organizational environment on EMI and also on the impact of EMI on the organizational performance of large-sized companies in emerging markets. Therefore, the results of this research are a step toward filling these gaps.
The relationships between DNA methylation levels and chorionicity in newborn twins

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Monozygotic (MZ) twins are currently used in epigenetic studies as one homogenous group. However, there are two MZ twin types: dichorionic (DC) and monochorionic (MC). We hypothesize that DCMZ twins are more similar epigenetically, compared to MCMZ twins, due to earlier zygote splitting, a higher degree of birth outcome similarity, or both. We recruited 220 newborn twins and obtained genome-wide DNA methylation profiles for 48 twins. Intraclass correlation coefficients (ICC) and linear mixed models were used to investigate the relationships between DNA methylation levels and chorionicity. DCMZ twins tended to have longer gestational age, larger birth weight, and smaller birth length discordance. DCMZ twins had more similar DNA methylation profiles than MCMZ twins (ICC=0.21 vs. 0.13), after adjusting for birth outcomes. Additionally, we identified 5,170 CpG sites with different DNA methylation levels between DCMZ and MCMZ twins. This study highlights the importance of incorporating chorionicity information in epigenetic twin studies.
WA 0822-1455-5757 Distributor Jual Herbalife di Slahung Ponorogo

Field: Business, Management and Accounting (Social Sciences)

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Do neighbourhood socioeconomic circumstances not matter for weight status among Australian men? Multilevel evidence from a household survey of 14 691 adults

Field: Social Sciences (Social Sciences)

Objective A recent analysis of the Australian National Health Survey (2011–2012) reported that the patterning of overweight and obesity among men, unlike for women, was not associated with neighbourhood socioeconomic disadvantage. The purpose of this study was to examine whether this gender difference in potential neighbourhood ‘effects’ on adult weight status can be observed in analyses of a different source of data. Design, setting and participants A cross-sectional sample of 14 693 people aged 18 years or older was selected from the 2012 wave of the ‘Household, Income and Labour Dynamics in Australia’ (HILDA). Three person-level outcomes were considered: (1) body mass index (BMI); (2) a binary indicator of ‘normal weight’ versus ‘overweight or obese’; and (3) ‘normal weight or overweight’ versus ‘obese’. Area-level socioeconomic circumstances were measured using quintiles of the Socio Economic Index For Areas (SEIFA). Multilevel linear and logistic regression models were used to examine associations while accounting for clustering within households and neighbourhoods, adjusting for person-level socioeconomic confounders. Results Neighbourhood-level factors accounted for 4.9% of the overall variation in BMI, whereas 20.1% was attributable to household-level factors. Compared with their peers living in deprived neighbourhoods, mean BMI was 0.7 kg/m 2 lower among men and 2.2 kg/m 2 lower among women living in affluent areas, with a clear trend across categories. Similarly, the percentage of overweight and obese, and obesity specifically, was lower in affluent areas for both men and women. These results were robust to adjustment for confounders. Conclusions Unlike findings from the national health survey, but in line with evidence from other high-income countries, this study finds an inverse patterning of BMI by neighbourhood disadvantage for men, and especially among women. The potential mediators which underpin this gender difference in BMI within disadvantaged neighbourhoods warrant further investigation.
Sokoto State University. 2024/2025 Admission Form on SALE Call @ (O7044935866).Also Direct Entry Form, masters form, P.H.D Form, Sandwich Form, Diploma Form, Transfer form, Change of School Form For 2024/2025 Session, FOR GUIDELINES AND ADMISSION ASSISTANCE CALL THE SCHOOL ADMIN ON @ 07044935866.

Field: Social Sciences (Social Sciences)

&lt;h3&gt;Sokoto State University. 2024/2025 Admission Form on SALE Call @ (O7044935866).Also Direct Entry Form, masters form, P.H.D Form, Sandwich Form, Diploma Form, Transfer form, Change of School Form For 2024/2025 Session, FOR GUIDELINES AND ADMISSION ASSISTANCE CALL THE SCHOOL ADMIN ON @ 07044935866.&lt;/h3&gt;
Characteristics of Small Farm Operators in Florida: Economics, Demographics, and Preferred Information Channels and Sources

Field: Agricultural and Biological Sciences (Life Sciences)

WC088, an 11-page illustrated report by Steven A. Gaul, Robert C. Hochmuth, Glenn D. Israel, and Danielle Treadwell, summarizes the results from the 2008 University of Florida IFAS Extension–Florida Agricultural and Mechanical University (FAMU) Small Farm Survey. This information can then be used by Extension faculty to identify target audiences, develop relevant materials, and deliver this information through appropriate channels to assist farmers in achieving the goals of their small farm enterprises. Includes references. Published by the UF Department of Agricultural Education and Communication, July 2009. WC088/WC088: Characteristics of Small Farm Operators in Florida: Economics, Demographics, and Preferred Information Channels and Sources (ufl.edu)