jimnoneill/paper-to-field-training huggingface dataset:
Effects of Mitochondria-Targeted Antioxidant Supplementation on Mitochondrial Adaptations to Endurance Training in Healthy Men

Field: Medicine (Health Sciences)

The production of reactive oxygen species (ROS) during exercise is one signal for training-induced mitochondrial biogenesis. Previous studies have shown that antioxidant supplementation blunts mitochondrial adaptations to exercise training via suppression of ROS production. PURPOSE: To determine the effects of mitochondria-targeted antioxidant (mtAO) supplementation on mitochondrial adaptations to chronic exercise training. METHODS: Young (22 ± 3 yr), healthy men (n = 19) were randomized to receive either mtAO (n = 9) or placebo (n = 10). Participants performed cycle training for 3-weeks at 50-70% of maximal oxygen uptake (VO2max). VO2max and an in vivo assessment of mitochondrial oxidative capacity were assessed before and after training. Mitochondrial oxidative capacity was assessed via post-exercise recovery kinetics of muscle oxygen consumption using near infrared spectroscopy (NIRS) in the vastus lateralis (VL) muscle. RESULTS: Exercise training increased VO2max (baseline: 40.1 ± 4.8 ml/kg/min; after training: 42.8 ± 3.9 ml/kg/min, main effect: p < 0.001), but no differences were detected between treatment groups (training × treatment: p = 0.29). Similarly, exercise training increased mitochondrial oxidative capacity rate constants (baseline: 1.8 ± 0.3 min-1; after training: 2.2 ± 0.5 min-1, main effect: p < 0.002), with no differences between treatment groups (training × treatment: p = 0.39). CONCLUSIONS: Mitochondria-targeted antioxidant supplementation does not alter mitochondrial adaptations to endurance exercise training. Further, our data indicate that three weeks of cycle training enhances mitochondrial oxidative capacity in the VL as measured by NIRS.
Positive psychological capital : a mediating factor between social skills and positive relations with others.

Field: Psychology (Social Sciences)

This study examined associations between social skills, positive relations with others and positive psychological capital (PsyCap) – the latter characterized by four constructs of hope, optimism, resiliency and self-efficacy. Using Baron and Kenny’s (1986) mediation framework, it was hypothesized that PsyCap, hope, optimism, resiliency, self-efficacy would each be a significant mediator of the association between social skills and positive relations with others. 206 undergraduates, aged 20 to 30 completed a measure of social skills, the PsyCap Questionnaire, and the Positive Relations with others scale. The previously significant relationship between social skills and positive relations was significantly reduced in magnitude when mediating variables were factored in. Sobel tests illustrated effects of the various partial mediation models.
“The Whole State Is On Fire”. Criminal Justice and the End of Reconstruction in Upcountry South Carolina1

Field: Social Sciences (Social Sciences)

Le 3 novembre 1876, on trouva les cadavres de deux meuniers allemands dans leur demeure incendiée située à quelques milles de la ville d'Aiken, dans le haut-pays de la Caroline du Sud. Les autorités blanches accusèrent immédiatement cinq Afro-américains de vol, meurtre et incendie volontaire. Leur inculpation, procès et exécution coïncida avec l'élection tendue de 1876 qui s'acheva par la prétendue Rédemption démocrate de la Caroline du Sud. Bien que les républicains fussent majoritaires au parlement de l'État, les racistes Démocrates avaient pris le contrôle de l'appareil judiciaire dans de nombreuses villes de l'État, y compris Aiken. En étudiant une affaire particulière d'homicide, cet article montre de quelle manière les Blancs manipulaient les tribunaux pour appuyer d'une violence légale leur campagne para-militaire contre les Afro-américains. Les procureurs Blancs requirent la peine de mort et, peu de temps après son accession aux fonctions de gouverneur, Wade Hampton approuva l'exécution des condamnés, effectuée en deux fois et qui ressembla à un lynchage, symbolisant l'échec de la Reconstruction.
Decoherence-Free Subspaces for Quantum Computation

Field: Computer Science (Physical Sciences)

Decoherence in quantum computers is formulated within the Semigroup approach.\nThe error generators are identified with the generators of a Lie algebra. This\nallows for a comprehensive description which includes as a special case the\nfrequently assumed spin-boson model. A generic condition is presented for\nerror-less quantum computation: decoherence-free subspaces are spanned by those\nstates which are annihilated by all the generators. It is shown that these\nsubspaces are stable to perturbations and moreover, that universal quantum\ncomputation is possible within them.\n
Short-term Efficacy of Agents Containing KNO3 or CPP-ACP in Treatment of Dentin Hypersensitivity.

Field: Dentistry (Health Sciences)

Both UltraEZ and MI Paste had a significant effect on dentin hypersensitivity. UltraEZ showed quicker effects than MI Paste, but MI Paste had a greater sustained action after treatment than UltraEZ.
Kirkjubømúrurin: L007

Field: Arts and Humanities (Social Sciences)

Sligin basalt steinur úr Kirkjubømúrinum, partur av steinasavninum hjá Tjóðsavninum. Krossur høgdur í steinin. *English:* Carved basalt stone from Kirkjubømúrinum (The Saint Magnus Cathedral), in storage at Tjóðsavnið. A cross has been carved into the stone Dimension: 28 x 43 x 18 cm. Created by Petur Hansen, using Artec space spider scanner and Artec Studio 15. Source: Objaverse 1.0 / Sketchfab
A Pilot Randomized Trial Evaluating the Cool 2 Be Safe Junior Playground Safety Program for Preschool Children

Field: Psychology (Social Sciences)

Abstract Objective Unintentional injury is the leading cause of death to children worldwide, and playgrounds pose a significant risk of injury. Those aged 5 and 6 years are particularly vulnerable to playground injuries. Previous interventions have typically targeted environmental modifications or increased supervision to reduce playground injuries; however, minimal research has focused on implementing behavioral interventions that seek to change children’s safety knowledge and risk-taking behaviors on the playground. The current randomized trial addressed these gaps in the literature and sought to increase preschool children’s hazard awareness skills and knowledge of unsafe playground behaviors and decrease their intentions to engage in risk-taking behaviors on the playground. Method A total of 77 children aged 5 and 6 years were tested at a laboratory on a university campus, using a parallel group design, with 38 randomized to the playground intervention group and 39 randomly assigned to a control group. The intervention was manualized and delivered to small groups of children (3–5) over several sessions. Results Statistical analyses revealed significant group differences. Intervention experience led to significant increases in hazard awareness skills and knowledge of unsafe playground behaviors, and significant decreases in children’s risk-taking behavioral intentions, whereas those in the control group showed no significant changes in these scores. Attention scores for those in the intervention group highlighted that the program content was successful in maintaining children’s attention and engagement, and memory scores indicated excellent retention of lesson content. Conclusion The program shows promise in addressing the issue of unintentional playground injuries in young children.
THE REGULATORY ROLE OF I‐J SUBREGION IN NEONATAL TOLERANCE INDUCTION TO H‐2D ALLOANTIGENS

Field: Immunology and Microbiology (Life Sciences)

Summary The mechanism of neonatally induced transplantation tolerance was studied in two mouse strain combinations involving differences at the D region of the H‐2 complex only or at the same D region plus I‐J subregion (including I‐E, I‐C, S and G regions). In the strain combination with the H‐2D difference only, cells from tolerant mice proliferated markedly in the MLR assay when incubated with antigens tolerated in vivo , whereas the MLR reactions were negative in the combination with D plus I‐J region disparities. In the latter combination cells from tolerant mice also did not respond to third‐party antigens and their incubation with the tolerated antigens led to the suppression of cell proliferation. This non‐specific suppression was absent in cells from tolerant mice in the strain combination, which differed in I‐C, S, G and D alloantigens. Specific suppressor cells, which inhibited the development of cytotoxic cells, were demonstrated in tolerant mice of both strain combinations. The results show that, in addition to the specific suppressor cells induced by H‐2K or H‐2D alloantigens, non‐specific suppressor cells induced by the I‐J region disparity that may regulate the resultant activity against H‐2D (and probably also H‐2K) alloantigens are involved in transplantation tolerance.
Ripple formation and its effect on the multi-scale microstructure of Directed Energy Deposition (DED)-printed 316L components

Field: Materials Science (Physical Sciences)

An experimental study is presented to characterize the ripple formations in the directed energy deposition (DED) process and study the influence of the ripples on the heterogenous microstructure in the scan direction of a DED-printed 316L components. While considerable studies on ripple formations exist in the welding literature, these formations in DED process have not received much attention. Also, little prior efforts exist on the microstructure along the scan direction (or the scan surface) as compared with the build direction. Experiments consisted of printing 10 mm x 10 mm x 10 mm cubical components on a Optomec LENS 500 Hybrid Machine Tool under different laser power, scan speed and dwell time combinations, chosen according to a Latin hypercube design. The surface of the scan face of the prints were finished to an Ra < 30 nm, and etched with Aqua regia for 90 sec. An optical microscope was employed to observe the microstructure at 4 difference scales. The studies suggest a significant influence of ripple formations as well as the scan width on the solidification front, the dendritic patterns as well as the heterogenous microstructure.
Effect of Tenispeculam maritimum Infection on Cultured Mugil capito

Field: Veterinary (Health Sciences)

A total number of (60) Mugil Capito (45 + 5 gm) obtained from floating cages at Rashid area, El-Behera Governorate, Egypt, were transported to the laboratory of fish diseases Department, Faculty of Veterinary Medicine, Alexandria University in oxygenated water, and acclimated for two weeks . The fish divided into 6 groups (10 fish / group), 2 groups used as control, while other groups infected with T. maritimum by half LD50 dose equal 0.5 (1.5 x 10 5 CF/ml) of water by prolonged immersion of fish for 18 hours at 18-20 C, then clinical signs, PM lesions and mortalities were recorded . Weekly sample were taken for histopathological examination for four weeks . Reisolation of the infected bacteria was determined for verification of death . The clinical signs was offood, sluggish movement and respiratory distress fish showed erythemia on body surface and around fins, darkness of skin coloration, opaqueness on the eye in some cases as well as fin and tail rot . The most predominant clinical signs were ulcers with different degrees . PM lesions showed sever congestion in kidney, gills, liver and the abdominal cavity filled with hemorrhagic ascetic fluids . Histopathlogical findings were lamellar telangiectasis of gills developed to multifocal fusion of secondary gill lamellae, congestion in hepatic sinusoids and vacular and hydropic degeneration of hepatic cell . In spleen the lymphoid cell depletion accompanied by telangiegiectosis of the red pulp and white pulps and depletion of blood elements in posterior kidney. PCR used for detection of T. maritimum which used in experimental infection . The results revealed that the primer sequence showed maximum identify with the sequence of T. maritimum with 100% hemology .
The effect of a modified nordic curl intervention on prevalence of hamstrings injuries in a professional football team

Field: Medicine (Health Sciences)

There are many discussions about the occurrence of hamstring injury, especially in running dominant sports such as Canadian rules football. Many interventions exist to decrease the risk and/or occurrence of hamstring injury, with the Nordic Curl being among one of the most studied interventions. The Nordic Curl is commonly implemented as part of a preventative injury program, often alongside various other methods of injury prevention exercises. Limited research exists on the implementation of a “more difficult” variation of the conventional Nordic Curl, which involves keeping the concentric portion in the exercise, as opposed to only completing the eccentric portion. This modified Nordic Curl (mNC) exercise was completed in one professional football team over the duration of four competitive seasons, post practice in a progressive manner to an upper limit of 5 reps per practice. Hamstring injury data collected during the four years of implementing the mNC was compared to the prior four years of hamstring injury data in three categories: rate of hamstring injuries per 4 years; average calendar days lost due to injury; and a comparison of total hamstring injuries per timeframe of the season. Independent t-tests were calculated to analyze for differences between rate of hamstring injuries in the two time periods (intervention vs non-intervention), and average time lost due to hamstring injury between the two time periods. Four Mann Whitney U tests were conducted to examine temporal differences in number of injuries between the intervention and non-intervention periods using four separate timeframes within the competitive season. No significant differences were found with any analyses, but large effect sizes were observed for differences between the groups for rate of hamstring injuries and the number of injuries that occurred in the first 6 weeks of the season. The results suggest the mNC does not significantly affect hamstring injury rates, time lost due to injury or specific timeframes within the competitive season. Future research should seek to investigate the modified version of the Nordic curl’s electromyographical output, as well as further study using a larger sample size than the current study.
A Multi-class image reranking algorithm based on multiple discrete-time quantum walk

Field: Computer Science (Physical Sciences)

To achieve multi-class image reranking, a novel image reranking algorithm using multiple discrete-time quantum walk is proposed. In this algorithm, a weighted undirected complete graph is first constructed, in which the nodes for the graph represent the images and the weighted values of these edges are the similarity value between the images. Secondly, it uses the spectral clustering to divide the images into $k$ classes and finds the representative image of each class. Thirdly, it uses the $k$ representative images as the initial state of quantum system, and the flip-flop shift operator and the weighted coin operator are used to control multiple discrete-time quantum walk on the weighted complete graph. Finally, the average probability values of the walker reaching the node of the graph is used as the relevance scores of the image, and then the images are reranked by the relevance scores. the experimental results show that our scheme has a significant enhance compared with the initial ranking algorithm from the comparison of visual and relevance scores. Furthermore, the effectiveness of our algorithm is evaluated by the average precision (AP) and the mean average precision (MAP), where the AP of our algorithm is increased by 53.21%, 31.75% and 14.29% for three types of the query image in randomly selected image group respectively, and the MAP of our algorithm is increased by 29.57% for all image groups compared with the initial ranking algorithm.
Additional file 14: of Tissue-specific transcriptomics and proteomics of a filarial nematode and its Wolbachia endosymbiont

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Table S8. Gene IDs, peptide spectral counts and protein descriptions for all 170 Wolbachia proteins detected by mass spectrometry in D. immitis tissues. (XLSX 56 kb)
VIRUS-LIKE PARTICLE VACCINE MANUFACTURING FROM YEAST

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Influenza virus has an intrinsic nature to undergo mutations. Hence, there have been struggles to combat this disease since the time when the worst influenza pandemic first hit in 1918. Vaccines have proved to be effective in controlling the spread of the influenza A virus by providing herd immunity. However, the contemporary design of influenza A virus based on egg and cell-culture is not efficient in tackling influenza A virus transformation. Virus-like particles (VLPs) have established themselves as a potental platform for future vaccine candidates. VLPs have all the credentials to supplant contemporary vaccine designs without compromising on immunogenicity. For expression of VLPs, yeast has all the definitive potential to develop new-generation influenza A vaccines. This report describes how to use Hansenula polymorpha, a yeast, to make VLPs of influenza H1N1 virus.
Retail security: a survey of methods and management in Dundee

Field: Social Sciences (Social Sciences)

Outlines preliminary results from a survey into retail security methods employed by retailers in central Dundee, and forms part of ongoing research into retail crime in this city being undertaken on a joint basis by the University of Abertay Dundee, and Tayside Police. Considers it to be the first survey of this type undertaken at such a local level in the UK. Concentrates on the types of physical and procedural security method employed, their perceived effectiveness from a managerial viewpoint, and which of the alternative security methods retail managers would utilize if they were given a free choice by their employers.
Impact of Innovation Technology in Enhancing Organizational Management

Field: Business, Management and Accounting (Social Sciences)

Digital technologies quick advancement prompts immersive remodeling of our economies and social orders that are entirely extensive. Innovative progress particularly in the area of artificial intelligence (AI), robotics, huge information and business analytics, also the increased and virtual reality are giving an all-out digital connectivity and recent conceivable outcomes for successful study and managing. Establishment anticipates higher efficiency and open doors for advanced execution by expanding utilization and integration of technology innovations. Not simply machines or shrewd calculations will accomplish assignments, however new types of human-machine communication show important influences for situating focal job of human in structure and advance exercises. In this study, the creators show a diagram of accessible technological solutions that (incorporating innovation) prompting new types of human-machine interaction and organizational management improvement. Moreover, features of advancement necessities producing thoughts in initial improve procedures are distinguished, organizational innovation is particularly pertinent in the present dynamic and turbulent environment, where other inside factors, for example, mechanical resources, employee training, synchronization of new management competences, flexible human capital, and increasingly versatile hierarchical design, are urged to make worth and upper hand. The objective behind this paper is to figure out whether technological assets impact organizational management procedure and how innovation technologies impact organizational management and performance. We accomplish these objectives by breaking down the organizational innovation and performance, using an integrative study methodology that brought out with data accumulated through perusing numerous articles that are connected to the theme and papers keywords.The finding of the research displays that help modernization and enhancement of mechanical aptitudes, inventive and innovative particular that include (web 2.0, Business Intelligence (BI), Artificial Intelligence (AI), enormous information, Internet of Think (IOT), industry 4.0 and social media) competencies advance enhancement in authoritative execution through its positive impact on the methods of potential and recognized adequacy, proficiency of decision making process.Primarily, traditional procedures of the firm affect organizational procedures as well as its performance. Further, interior work adaptability impacts organizational performance through innovation. This concern specifically interest when considering the changing idea of tempestuous mechanical situations wherein association works. Technological resources in this manner recognize new wellsprings of adaptability and organizational development subject to progressively significant logical information and instruments that controls data volume in the organization.
Mouse Models of Human Pathogenic Variants of TBC1D24 Associated with Non-Syndromic Deafness DFNB86 and DFNA65 and Syndromes Involving Deafness

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Human pathogenic variants of TBC1D24 are associated with clinically heterogeneous phenotypes, including recessive nonsyndromic deafness DFNB86, dominant nonsyndromic deafness DFNA65, seizure accompanied by deafness, a variety of isolated seizure phenotypes and DOORS syndrome, characterized by deafness, onychodystrophy, osteodystrophy, intellectual disability and seizures. Thirty-five pathogenic variants of human TBC1D24 associated with deafness have been reported. However, functions of TBC1D24 in the inner ear and the pathophysiology of TBC1D24-related deafness are unknown. In this study, a novel splice-site variant of TBC1D24 c.965 + 1G > A in compound heterozygosity with c.641G > A p.(Arg214His) was found to be segregating in a Pakistani family. Affected individuals exhibited, either a deafness-seizure syndrome or nonsyndromic deafness. In human temporal bones, TBC1D24 immunolocalized in hair cells and spiral ganglion neurons, whereas in mouse cochlea, Tbc1d24 expression was detected only in spiral ganglion neurons. We engineered mouse models of DFNB86 p.(Asp70Tyr) and DFNA65 p.(Ser178Leu) nonsyndromic deafness and syndromic forms of deafness p.(His336Glnfs*12) that have the same pathogenic variants that were reported for human TBC1D24. Unexpectedly, no auditory dysfunction was detected in Tbc1d24 mutant mice, although homozygosity for some of the variants caused seizures or lethality. We provide some insightful supporting data to explain the phenotypic differences resulting from equivalent pathogenic variants of mouse Tbc1d24 and human TBC1D24.
Designing Parent-child-robot Interactions to Facilitate In-Home Parental Math Talk with Young Children

Field: Computer Science (Physical Sciences)

Parent-child interaction is critical for child development, yet parents may need guidance in some aspects of their engagement with their children. Current research on educational math robots focuses on child-robot interactions but falls short of including the parents and integrating the critical role they play in children's learning. We explore how educational robots can be designed to facilitate parent-child conversations, focusing on math talk, a predictor of later math ability in children. We prototyped capabilities for a social robot to support math talk via reading and play activities and conducted an exploratory Wizard-of-Oz in-home study for parent-child interactions facilitated by a robot. Our findings yield insights into how parents were inspired by the robot's prompts, their desired interaction styles and methods for the robot, and how they wanted to include the robot in the activities, leading to guidelines for the design of parent-child-robot interaction in educational contexts.