jimnoneill/paper-to-field-training huggingface dataset:
Chicago School Closings Shadow Report: Independent Information for the 107th session of the Human Rights Committee

Field: Social Sciences (Social Sciences)

The City of Chicago recently closed 49 public elementary schools in an attempt to address budgetary and resource constraints. This is the largest wave of school closings in United States history, involving 10% of all public schools in Chicago, the third largest city in the country. Although there are many schools considered “underutilized” in Chicago, those that were targeted for closing were majority African American. The closings affected nearly 30,000 children and have had a disproportionate and negative impact on minority and disabled children. Displaced students will be packed into classrooms with more students, resulting in overcrowded classrooms. The school closings also place children at greater risk of violence and death as many children will be forced to cross gang lines on their way to new schools. The appointment structure of the Chicago Board of Education does not allow for democratic participation and indeed, by failing to pay heed to the widespread opposition to the school closings, the City of Chicago effectively denied people the right to participate in deciding whether or not to close the schools.\nU.S. courts have failed to take action to stop the school closings. In August 2013, a federal district court judge denied a request for a preliminary injunction to stop the school closings filed by parents of children affected by the closings, with support from the Chicago Teachers Union. A separate request for an emergency injunction filed in federal court seeking to stop the closure of an elementary school with a large population of children with special needs was also denied. A third lawsuit filed by the Chicago Teachers Union in Cook County Circuit Court that sought to stop the closure of ten schools was also unsuccessful.
Authorities at play in Indigenous language reclamation: tensions and possibilities in the Yucatan Peninsula

Field: Social Sciences (Social Sciences)

Abstract Language revitalization efforts have been critiqued for creating and reproducing linguistic, epistemological, and pedagogical hierarchies that might run counter to a community’s needs and interests. Drawing on a seven-year ethnographic and collaborative research with the Maya cultural promoters of the Caste War Museum in Tihosuco, Mexico, we describe the dynamics of our Maya language reclamation partnership focusing on the creation of bilingual comic books and summer workshops for children. These experiences show a slow but steady language reclamation approach based on the concern for younger generations to feel comfortable to claim their right to speak and learn Maya and on their fondness for Maya language and culture. We argue that the construction, negotiation, and assertion of linguistic and pedagogical authority among all participating actors is central to reclamation projects, and that these processes are impacted by outsider researchers-collaborators in ways that can support but also potentially harm these language efforts. This paper sheds light on the various tensions lived in long-term language reclamation projects, recognizing the need for outsider researchers to turn our reflexive gaze inwards and consider how we can bring to the fore practices we can celebrate as well as address and transform those that cause discomfort and uncertainty.
Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis

Field: Neuroscience (Life Sciences)

Homozygous nonsense mutations in CEP55 are associated with several congenital malformations that lead to perinatal lethality suggesting that it plays a critical role in regulation of embryonic development. CEP55 has previously been studied as a crucial regulator of cytokinesis, predominantly in transformed cells, and its dysregulation is linked to carcinogenesis. However, its molecular functions during embryonic development in mammals require further investigation. We have generated a Cep55 knockout (Cep55-/-) mouse model which demonstrated preweaning lethality associated with a wide range of neural defects. Focusing our analysis on the neocortex, we show that Cep55-/- embryos exhibited depleted neural stem/progenitor cells in the ventricular zone as a result of significantly increased cellular apoptosis. Mechanistically, we demonstrated that Cep55-loss downregulates the pGsk3β/β-Catenin/Myc axis in an Akt-dependent manner. The elevated apoptosis of neural stem/progenitors was recapitulated using Cep55-deficient human cerebral organoids and we could rescue the phenotype by inhibiting active Gsk3β. Additionally, we show that Cep55-loss leads to a significant reduction of ciliated cells, highlighting a novel role in regulating ciliogenesis. Collectively, our findings demonstrate a critical role of Cep55 during brain development and provide mechanistic insights that may have important implications for genetic syndromes associated with Cep55-loss. Author summary Despite extensive investigation on the roles of CEP55 in tumorigenesis, its physiological role during development has remained largely uncharacterized. Recently, homozygous CEP55 mutations have been linked to two lethal fetal syndromes, MKS-like Syndrome and MARCH, demonstrating the importance of CEP55 in embryogenesis and neural development. These syndromes exhibit multiple severe clinical manifestations that lead to perinatal lethality. However, the exact molecular mechanism underlying complex Cep55-deficient developmental phenotypes remain elusive. To address this question, we have generated a Cep55-/- (KO) mouse model and to bridge the gap between the mouse model and human disease, we have used brain organoids generated from pluripotent stem cells as a promising approach to investigate the mechanism of Cep55-associated neurodevelopment phenotype. Our detailed mechanistic studies suggest that Cep55 regulates neural development through the Akt-downstream effector, Gsk3β, and its mediators β-Catenin and Myc, which are known regulators of neural proliferation and differentiation. Additionally, we discovered a critical role for Cep55 in regulating cilia formation. Together, these results illustrate an important role of Cep55 in regulating neurogenesis and ciliogenesis via regulation of the Akt pathway.
Comparative Efficacy of Bacillus thuringiensis Commercial Formulations against Leaf Worm, Spodoptera litura Fabricius under Laboratory Conditions

Field: Agricultural and Biological Sciences (Life Sciences)

Rawalpindi to check the efficacy of commercial biopesticides under controlled environmental conditions.Bio pesticides are important alternates for chemical control of economically damaging insect pests like leaf worm, Spodoptera litura Fabricius.In this study, two commercial products including Dipel with Bt sub speciess kurstaki and Turex with Bt sub speciess kurstaki and aizawai were tested against three early larval instars of S. litura under laboratory conditions using leaf dip method.Mortality was recorded after three and seven days of exposure.The results indicated that larval mortality increased with time and Turex (Bt sub speciess kurstaki and aizawai) after 3 days of exposure caused significantly higher mortality i.e 46.43, 43.45 and 38.69 % as compared to Dipel (Bt sub speciess kurstaki) that caused 19.05, 6.55 and 4.76 % mortality for 1 st , 2 nd and 3 rd instar, respectively.The data for 7 th day also showed significantly higher mortality as 64.29, 60.71 and 45.24 % by Turex (Bt sub speciess kurstaki and aizawai) in comparison with 55.95, 57.74 and 42.86 % mortality by Dipel (Bt sub species kurstaki) for 1 st , 2 nd and 3 rd instar, respectively.Susceptibility to both bio pesticides increased with increase in their concentration and decreased with increase in larval instar.Similarly LC 50 values suggested Turex (Bt sub species kurstaki and aizawai) to be more toxic with less LC 50 values as compared to Dipel (Bt sub species kurstaki).These results indicated that these bio pesticides if used at early insect stage can help to control this pest.
Occurrence Download

Field: Agricultural and Biological Sciences (Life Sciences)

A dataset containing 17 species occurrences available in GBIF matching the query: { "TaxonKey" : [ "is Nasa moroensis Weigend" ] } The dataset includes 17 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0045455-230530130749713/datasets/export for details. Data from some individual datasets included in this download may be licensed under less restrictive terms.
Correlation Study of Stroke Morbidity with the Clinical Symptom Score of Stroke Precursor of Qi deficiency and Blood Stasis Pattern/Syndrome

Field: Medicine (Health Sciences)

Objective To explore the clinical symptom scores of stroke precursor of qi deficiency and blood stasis pattern/syndrome and predict the possibility of stroke morbidity through the research of the correlation of stroke morbidity with the clinical symptom scores of stroke precursor of qi deficiency and blood stasis pattern/syndrome.Methods 62 cases of stroke precursor of qi deficiency and blood stasis pattern/syndrome were selected as the research objects.The terminal point was determined by whether stroke attacked or not in 12 months.It was to record the sex,age,smoking and alcoholic history,family history,body mass index,the compliance of risk factor intervention and the clinical symptom scores of Chinese medicine.It was to study the main impact factors of stroke.Results The body mass index,the compliance of risk factor intervention and the clinical symptom score of Chinese medicine were correlative with stroke(P0.05).The logistic regression analysis indicated that the clinical symptoms of Chinese medicine and the compliance of risk factor intervention were the independent factors of stroke.Conclusion The independent factors of stroke in 12 months of the occurrence of stroke precursor include the clinical symptoms of Chinese medicine and the compliance of risk factor intervention.
Intracytoplasmic sperm injection — ICSI

Field: Medicine (Health Sciences)

For more than a decade in vitro fertilization (IVF) has been successful in the treatment of couples with long-standing infertility due to various aetiologies such as tubal disease, male-factor infertility, unexplained infertility and endometriosis. The usual fertilization rate in IVF for nonmale infertility cases is 60–70% of the inseminated cumulus-oocyte complexes and in andrological infertility it is only 20–30%. The lower the number of normally fertilized oocytes, the less chance there is of available embryos, so that patients may have no embryos to transfer. It has been the experience of all centres for reproductive medicine, including our own, that a certain number of couples with male-factor infertility cannot be helped by standard IVF treatment. After insemination with progressively motile spermatozoa the number of two-pronuclear oocytes was either zero or less than 5%. Furthermore, a sizeable number of couples cannot be accepted for IVF if the number of progressively motile spermatozoa in the ejaculate is below a certain threshold number such as 500 000. In the past five years, assisted fertilization procedures have been developed to circumvent the barriers that prevent sperm access to the ooplasma, namely the zona pellucida and the ooplasmic membrane. Pregnancies and births have been reported after partial zona dissection (PZD) and subzonal insemination (SUZI). The success rate of PZD and SUZI has remained moderate: the normal fertilization rate (two-pronuclear oocytes) has never exceeded 20–25% of the micromanipulated oocytes; only two-thirds of the patients have had embryo transfers of, usually, a low number of embryos, resulting in a reduced pregnancy and take-home baby rate.
Linked collectors and determiners for: Three new species of the genus Neuquenaphis (Hemiptera, Aphididae, Spicaphidinae) from southernmost South America.

Field: Agricultural and Biological Sciences (Life Sciences)

Natural history specimen data linked to collectors and determiners held within, "Three new species of the genus Neuquenaphis (Hemiptera, Aphididae, Spicaphidinae) from southernmost South America". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/d8837133-c1e6-4024-b530-3de27907aa51 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/d8837133-c1e6-4024-b530-3de27907aa51. Formatted as a Frictionless Data package.
The Effect of Lack of a Carbon Source on Nitrate-reductase Activity in Aspergillus nidulans

Field: Immunology and Microbiology (Life Sciences)

Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our principal goal to develop, expand and strengthen the networks available to our members so that they can generate new knowledge about microbes and ensure that it is shared with other communities.
On the motivation of social and life success of the athlete’s personality

Field: Psychology (Social Sciences)

The article argues that the XXI century is the pinnacle of time, when a person plays a predominant role in any relationship. The future involves the emergence of artificial intelligence that surpasses the human mind, the past underestimates the importance of each personality, its capital for the life of society as a whole. The article investigates the motivation of social and life success of the athlete’s personality. Status roles are identified, roles related to motivation are analyzed. The definition of the concept of “success” in the life of an athlete is given. As a result of the survey it is established that for students of the National State University of Physical Culture, Sports and Health (NSU) named after P. F. Lesgaft the definition of life values is one of the main tasks to achieve success.
Development of Enhanced Analytical Methodology in Pesticide Chemistry

Field: Chemistry (Physical Sciences)

The analysis of pesticide residues in fruit, vegetables, rape seed and water has been improved using developments in sample handling and analytical techniques. The method development is associated with analytical difficulties, since pesticides currently used in agriculture represent a variety of chemical classes having very different physico chemical properties. The method development also encounters difficulties when many various commodity classes with different characteristics are studied. The main task in pesticide residue analysis has been to provide multi residue methods, and traditionally GC has been the main analytical technique. In order to regulate the use of hazardous pesticides, the EU commission introduces strict maximum residue levels (MRL). The need for improved sample handling and detection techniques are, however, high due to handling of lower detection limits, complex matrices and the need of more efficient sample throughput. Of the new techniques introduced as alternative techniques to the traditional extraction techniques, pressurised fluid extraction (PFE) has shown to be a promising technique in analysis of pesticide residues in fatty foodstuffs. In water analysis, large sample volumes are needed due to low MRLs. The solid phase extraction (SPE) technique allows a concentration of large sample volumes and simplifies the tedious laboratory work with traditional separation funnels. A new approach was to use non-polar solvents for the sample extraction from the earlier used polymeric column. Both these techniques provide low solvent consumption, short extraction times and ability to automate the manual steps. An LC-MS/MS multi residue method was finally developed for pesticide residues in fruit and vegetables. The technique is robust and sensitive and allows a simultaneous determination of 57 pesticides and metabolites in one single analysis and without any clean-up steps. The sensitivity was improved to achieve the maximum residue limits needed by EU. Several multi step methods, which involve more costly analysis, has been replaced by this technique.
22, Conveyance with Two Partial Pendant Seals, Concerning Land Transfer in Kimbolton

Field: Arts and Humanities (Social Sciences)

"A conveyance by Richard Gayows the Elder (formerly of Catworth in Huntingdonshire) and Thomas Lewys (formerly of Tilbrook in the same county) to Robert Portesoyll and others of land in Wornditch, Kimbolton, beside that owned by the Duke of Buckingham. The land in question is a manse, 12 acres of farmland, and a pasture, and it is noteworthy that the two owners transfer this property to no fewer than eight persons, Portesoyll (a soldier), John Phillips (rector of the church of Shelton), and six others.” [from dealer's note] Written in 15th century secretary hand in Latin. Stain from paper clip at upper right, one horizontal and two vertical folds; otherwise the vellum is very clean and the text quite legible. Two wax seals attached: approximately three-fourths of one seal missing, the other nearly all present. Rose-Wright Manuscript Collection no. 14
A Novel Virtual Sensor Modeling Method Based on Deep Learning and Its Application in Heating, Ventilation, and Air-Conditioning System

Field: Computer Science (Physical Sciences)

Realizing the dynamic redundancy of sensors is of great significance to ensure the energy saving and normal operation of the heating, ventilation, and air-conditioning (HVAC) system. Building a virtual sensor model is an effective method of redundancy and fault tolerance for hardware sensors. In this paper, a virtual sensor modeling method combining the maximum information coefficient (MIC) and the spatial–temporal attention long short-term memory (STA-LSTM) is proposed, which is named MIC-STALSTM, to achieve the dynamic and nonlinear modeling of the supply and return water temperature at both ends of the chiller. First, MIC can extract the influencing factors highly related to the target variables. Then, the extracted impact factors via MIC are used as the input variables of the STA-LSTM algorithm in order to construct an accurate virtual sensor model. The STA-LSTM algorithm not only makes full use of the LSTM algorithm’s advantages in handling historical data series information, but also achieves adaptive estimation of different input variable feature weights and different hidden layer temporal correlations through the attention mechanism. Finally, the effectiveness and feasibility of the proposed method are verified by establishing two virtual sensors for different temperature variables in the HVAC system.
On the verbal organization of L2 tense marking in an elicited translation task by Spanish immigrants in Germany

Field: Arts and Humanities (Social Sciences)

This article describes the undirected learning (learning without explicit teaching) of tense markers in German by Spanish migrant workers. It will be shown that the remarkable differences the informants displayed in expressing the concept of tense are a function of the daily communicative routines which they developed in order to meet their communicative needs and demands. By examining very simplified learner varieties, I will demonstrate that a traditional grammatical analysis of tense is not capable of accounting for the wide range of expressions for temporal relations which were produced in an elicited Spanish-German translation task.
Helium Production in Solid Target and Metallic Window Materials Irradiated with Intermediate and High Energy Protons

Field: Physics and Astronomy (Physical Sciences)

Abstract The helium isotope formation cross-section has been obtained for iron, tantalum and tungsten irradiated with protons at energies from the reaction threshold up to several GeV. The cross-section evaluation has been performed using the results of model calculations and by the analysis of available experimental data. The numerical calculations were carried out using the modified ALICE code and the CASCADE/INPE code. KEYWORDS: protonsintermediate energies high energieshelium 4helium 3 isotope productioncrosssectionevaluationirontantalumtungsten
Morphology via Orthography: A Visual Approach to Oral Decisions

Field: Arts and Humanities (Social Sciences)

Can a language rule impede learners' oral accuracy&quest; The standard ESL&sol;EFL presentation of the &lcub;Z&rcub; and &lcub;D&rcub; morphemes of English requires the distribution of allomorphs according to the phonological characteristics of stem-final sounds. Examined from the learner's point of view, the standard approach is heavily biased against beginning students. This study offers an alternative approach that is heavily biased in favor of beginning students but is no less precise in its predictions. It requires the distribution of allomorphs according to orthographic criteria. Learners from different language backgrounds and different proficiency levels who used the orthography-based approach improved their oral accuracy to such an extent that performance differences originally attributable to their dissimilar language backgrounds and proficiency levels disappeared. The significant progress of students who learned the orthography-based rules suggests that the morpheme errors of those who learned only the standard rules may be the result of instruction, not the result of difficult content.
Levosimendan as Treatment Option in Severe Verapamil Intoxication: A Case Report and Review of the Literature

Field: Medicine (Health Sciences)

Copyright © 2010 Mirjam Osthoff et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Cardiovascular shock due to verapamil intoxication is often refractory to standard resuscitation methods. Recommended therapy includes prevention of further absorption of the drug, inotropic therapy, calcium gluconate, and hyperinsulinemia/euglycemia therapy. Often further measures are needed such as ventricular pacing or mechanical circulatory support. Still, mortality remains high. Levosimendan, an inotropic agent, that enhances myofilament response to calcium, increases myocardial contraction and could therefore be beneficial in verapamil intoxication. Here, we report the case of a 60-year-old patient with clinically severe verapamil poisoning who presented with shock, bradycardia, and sopor. Standard therapy including high-dose inotropes failed to ameliorate the signs of intoxication. But additional therapy with levosimendan led to rapid improvement. Based on this observation, the literature is reviewed focusing on utilization of levosimendan in the treatment of calcium channel blocker overdose. We suggest to consider levosimendan as additional treatment option in patients with cardiovascular shock due to verapamil intoxication that are refractory to standard management. 1.
Multi-Spectral Widefield Microscopy of the Beating Heart Through Post-Acquisition Synchronization and Unmixing

Field: Computer Science (Physical Sciences)

Multi-spectral imaging allows distinguishing biological structures. For cardiac microscopy, available devices are either too slow or require illumination intensities that are detrimental to the sample. We present a method for spectral super-resolution imaging of samples whose motion is quasi-periodic by sequentially acquiring movies in wavelength ranges with filters of overlapping bands. Following an initial calibration procedure, we synchronize and unmix the movies to produce multi-spectral sequences. We characterized our approach to retrieve the transmittance of a colored microscopic target whose motion we controlled, observing measurements within of 10% that of a reference spectrometer. We further illustrate our approach to observe the beating embryonic zebrafish heart, demonstrating new possibilities for studying its development