jimnoneill/paper-to-field-training huggingface dataset:
Linking Afro-Asian and European Traces of Bovine Veneration to India’s Sacred Cow

Field: Arts and Humanities (Social Sciences)

India is unique among many contemporary cultures because parts of its Hindu population continue to revere an animal that is an important contributor to the survival of many pastoral and agricultural communities, the cow. Yet the cow also played a significant cosmological role in the lives of numerous peoples who inhabited the regions west of India. Visual remains in the form of bones from cattle burials, depictions of bovid iconography in cave art, pottery, relief and sculpture, as well as cow imaginings rendered visible through mythological accounts, point toward how the cow appears to have been associated with notions of creation and the divine feminine, which along with ideas of abundance, fertility and well being, are attributed to her by countless Hindus today.
Applying full-azimuth depth processing in the Local Angle Domain for Frequency Absorption versus Azimuth) (FAVAz) analysis to predict permeable, oil-saturated fractures

Field: Earth and Planetary Sciences (Physical Sciences)

Predicting the permeability of fractured reservoirs is valuable for both reservoir assessment and drilling planning. Characterization of such systems requires advanced amplitude analysis, mainly based on seismic imaging results of the recorded wavefield. A significant amount of work has been done on the subject over the past few decades.
Student-centered education - a priority for the academic environment

Field: Social Sciences (Social Sciences)

This paper outlines an overview of what student-centered education (SCE) means - a priority of the Bologna process. Thanks to the emergence of new educational needs and the modernization of the university education curriculum in our country, currently, there is an increased interest in this way of training. It also analyzes the concept and definition, presents the basic principles and dimensions of the SCE. At the same time, a comparative analysis of the two systems that coexist in local higher education is performed: student-centered education and teacher-centered education. In order to focus on the needs of students, to ensure a quality teaching process, mainly focused on the formation of skills necessary for professional activity, the benefits offered by the SCE model to both students and teachers are highlighted.
Length-to-weight and length-to-length relations of 15 freshwater fish species (Actinopterygii: Cypriniformes) from the Oujiang River, China

Field: Agricultural and Biological Sciences (Life Sciences)

Length-to-weight and length-to-length relations were estimated for 15 freshwater fishes belonging to the order Cypriniformes from Yuxi power station to Kaitan reservoir dam trunk stream of the Oujiang River, Zhejiang Province, China. The following species were studied: Distoechodon tumirostris Peters, 1881, Xenocypris davidi Bleeker, 1871, Plagiognathops microlepis (Bleeker, 1871), Hemibarbus labeo (Pallas, 1776), Hemibarbus maculatus Bleeker, 1871, Chanodichthys erythropterus (Basilewsky, 1855), Culter alburnus Basilewsky, 1855, Chanodichthys dabryi (Bleeker, 1871), Opsariichthys bidens Günther, 1873, Zacco platypus (Temminck et Schlegel, 1846), Sinibrama macrops (Günther, 1868), Hemiculter leucisculus (Basilewsky, 1855), Pseudohemiculter hainanensis (Boulenger, 1900), Rhodeus sinensis Günther, 1868, and Squalidus argentatus (Sauvage et Dabry de Thiersant, 1874). The determination coefficients r 2 of LWRs were all over 0.96, and the 15 values of parameter b were consistent with the predicted range of 2.5–3.5. The total length-to-standard length relations were also calculated with r 2 ≥ 0.97. Our study provides new information on LWR for 1 species and LLRs for 8 species, as well as new maximum total length recorded for 4 species (i.e., Distoechodon tumirostris , Opsariichthys bidens , Pseudohemiculter hainanensis , and Rhodeus sinensis ) in FishBase. This study is expected to provide a useful baseline for further studies of population parameters to improve management decisions on the Oujiang River.
The role of women in conflict making and peacemaking in “The Troubles”: A study of Northern Irish Women

Field: Social Sciences (Social Sciences)

Northern Ireland’s troubled past has been subjected to a vast amount of historical analysis. The role of women in the Northern Ireland Civil War, both as conflict makers and peace makers has however been neglected and minimized. The lack of emphasis or importance placed on the role of women, both in paramilitary roles as well as in peace-keeping roles is obvious and unsettling. Analysis of this time period focuses heavily on the role of key politicians such as previous Democratic Unionist Party (D.U.P.) leader Ian Paisley and Nationalist party Sinn Fein leaders Gerry Adams and Martin McGuinness, as well as the actions of the numerous paramilitary groups. Two areas where this gap seems most prominent are in analysis of female political prisoners and in recognizing the importance of cross-community action taken by women in a highly segregated community such as this. I aim to rectify this through an analysis of policy, media dialogue and oral history. This research will advance study of social justice in a Northern Ireland context by focusing on an area that has largely been missing in the quest for Civil Rights for Catholics as well as equality for women in a segregated community, where what community you belong to becomes the priority.
Using the World Wide Web for Community Outreach: Enriching Library Service to the Community

Field: Arts and Humanities (Social Sciences)

Abstract Through Our Parents' Eyes: Tucson's Diverse Community, includes a series of World Wide Web exhibits that share the history and experiences of Tucsonans from a variety of ethnic back-grounds. Its purpose is to acknowledge our multi-cultural heritage through digital histories that combine historical images and text with stories of Tucson told by some of Tucson's founding members. Through Our Parents' Eyes demonstrates how libraries and archives can create a vehicle for outreach and establish a powerful presence in their communities. This article describes the experiences of University of Arizona and Pima Community College librarians in building World Wide Web exhibits featuring traditionally underrepresented groups in the Tucson, Arizona, community. It provides a foundation from which new Web projects may be developed by highlighting the key elements to the project: developmental considerations, goal setting, costs, benefits, and rights and permissions. It concludes with recommendations for other librarians and archivists on planning, implementing, and supporting community-based Web projects.
PRT2527, a Novel Highly Selective Cyclin-Dependent Kinase 9 (CDK9) Inhibitor, Has Potent Antitumor Activity in Combination with BTK and BCL2 Inhibition in Various Lymphoid Malignancies

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

CDK9 is a master regulator of transcription that modulates transcription elongation via phosphorylation of RNA polymerase II. Short-term inhibition of CDK9 depletes short-lived transcripts and labile proteins such as MCL1, BFL1 and MYC to promote cancer cell death. We previously described PRT2527, a novel, potent, highly selective CDK9 inhibitor with anti-leukemic activity in various preclinical models. PRT2527 is currently under evaluation in a Phase I clinical trial in patients with relapsed/refractory hematologic malignancies (NCT05159518). Here we demonstrate PRT2527 potently inhibits cancer growth and induces cell death in various models of Diffuse Large B Cell Lymphoma (DLBCL), Mantle Cell Lymphoma (MCL) and Chronic Lymphocytic Leukemia (CLL), through depletion of MCL1, BFL1 and MYC. We also show that combination of PRT2527 with BTK inhibitors (BTKi) or BCL2 inhibitors (BCL2i) leads to more robust and durable responses in multiple pre-clinical models. In these studies, the combination of PRT2527 with BTKi or BCL2i was well tolerated. Mechanistically, we show that in cell lines, BTK inhibition upregulates BMF, an endogenous inhibitor of BCL2 and BCL-xL, driving cells towards MCL1 and BFL1 dependency. Concurrent depletion of MCL1 and BFL1 with PRT2527 led to complete inhibition of Bcl-2- family mediated survival signaling, potently inducing cell death. In a similar fashion, Venetoclax-driven BCL2 inhibition also potentiated the anti-tumor activity of PRT2527. Consistent with our findings in vitro, we confirmed potent combinatorial inhibition of tumor growth by PRT2527, administered once weekly, and BTKi or BCL2i, administered daily, in CDX and PDX in vivo models of DLBCL and MCL. We observed reduced BFL1 and MCL1 as well as increased BMF in tumors of mice treated with BTKi and PRT2527 suggesting complete Bcl-2 family inhibition. We also demonstrated enhanced induction of apoptosis by PRT2527 in primary CLL patient samples simultaneously treated with BTKi or BCL2i. Additionally, we demonstrated that PRT2527 potently inhibits growth in Ibrutinib-resistant MCL cell lines. Further work characterizing PRT2527 as monotherapy and in combination with BTKi and BCL2i in in vivo models of BTKi-resistant MCL and CLL is currently ongoing. Altogether these data provide a rationale for evaluating PRT2527 in combination with BTK and BCL2 inhibitors for the treatment of patients with relapsed/refractory hematologic malignancies.
Migration and social uses of facebook: An Approach to Senegalese Web Diaspora in Rio Grande do Sul

Field: Social Sciences (Social Sciences)

Abstract This article begins with a discussion about relations between network communication and transnational migration. The concept of webdiaspora is also presented. In the second part of the paper, four Facebook pages of Senegalese migrants living in Rio Grande do Sul are analyzed. In this work paper, Facebook is understood as part of migration dynamics, like a communication environment of identity affirmation. Likewise, Facebook is considered to be a meeting place of a diaspora that is organized in terms of associations for recognition policies in Brazil. The text is part of a communication research about TICs and migration dynamics between Senegal and Rio Grande do Sul.
Urological Oncology: Testis Cancer and Advances in Oncologic Therapy

Field: Medicine (Health Sciences)

No AccessJournal of UrologyUrological Survey1 Sep 2022Urological Oncology: Testis Cancer and Advances in Oncologic Therapy Jerome P. RichieMD Jerome P. RichieJerome P. Richie More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002820AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Urological Oncology: Testis Cancer and Advances in Oncologic Therapy." The Journal of Urology, 208(3), pp. 738–739 © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 208Issue 3September 2022Page: 738-739 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Jerome P. Richie More articles by this author Expand All Advertisement PDF downloadLoading ...
Frequency-independent equivalent-circuit model for on-chip spiral inductors

Field: Engineering (Physical Sciences)

A wide-band physical and scalable 2-π equivalent circuit model for on-chip spiral inductors is developed. Based on physical derivation and circuit theory, closed-form formulas are generated to calculate the RLC circuit elements directly from the inductor layout. The 2-π model accurately captures R(f) and L(f) characteristics beyond the self-resonant frequency. Using frequency-independent RLC elements, this new model is fully compatible with both ac and transient analysis. Verification with measurement data from a SiGe process demonstrates accurate performance prediction and excellent scalability for a wide range of inductor configurations.
Side Effects of Anthracycline Chemotherapy on the Heart of Laboratory Animals

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Anthracycline is one of the chemical drugs commonly used worldwide for the treatment of various types of cancer. The high doses of it cause unwanted toxic side effects on the tissues. Our study designed to demonstrated the physiological and histopathological effect of the drug on the heart organ of experimental animals. For this purpose, twenty adults male rats were used in this study and were divided into four main groups. Control group, Azoxymethane treated group, Azoxymethane qrand anthracycline treated group, and anthracycline treated group only. Blood of the experimented animals was collected in order to measure biochemical parameters such as glutathione, lactate dehydrogenase, malondialdehyde, peroxynitrite, Creatinine Kinase, C-reactive protein Creatine kinase –myocardial band, and Myoglobin concentrations. In this study a significant increase and decrease was observed in biochemical parameters. Histological examination on the heart shown that rats treated with AOM have been revealed only hypertrophy of cardiac muscles, while other groups were observed hypertrophy of cardiac muscles furthermore. Aorta in AOM group have been revealed Adverse histological changes and transformation in the thickness aortic wall layers. The tissue sections of the groups treated with Anthracyclin showed a negative effect on the aortic wall layers, the endothelial layer and the middle layer, as well as the outer layer in the sections prepared from these groups.
LENGTH VARIATION AND HETEROPLASMY ARE FREQUENT IN MITOCHONDRIAL DNA FROM PARTHENOGENETIC AND BISEXUAL LIZARDS (GENUS CNEMIDOPHORUS)

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

ABSTRACT Samples of mtDNA isolated from each of 92 lizards representing all color pattern classes of Cnemidophorus tesselatus and two populations of C. tigris marmoratus were digested with the restriction endonucleases MboI, TaqI, RsaI and MspI. The mtDNA fragment sizes were compared after radioactive labeling and gel electrophoresis. Three features were notable in the comparisons: (1) there was little variation due to gain or loss of cleavage sites, (2) two fragments varied noticeably in length among the samples, one by a variable amount up to a maximum difference of ∼370 base pairs (bp) and the other by a discrete amount of 35 bp, (3) these two fragments occasionally varied within, as well as between, samples. Two regions that corresponded in size to these variants were identified by restriction endonuclease cleavage mapping. One of these is adjacent to the D-loop. Heteroplasmy, heretofore rarely observed, occurred frequently in these same two regions. Variability in the copy number of a tandemly repeated 64-bp sequence appears to be one component of the variation, but others (e.g., base substitutions or small additions/deletions) must also be involved. The frequent occurrence of these length variations suggests either that they can be generated rapidly or that they were inherited from a highly polymorphic ancestor. The former interpretation is favored.
Cadastres, Including Some Aspects of Assessment of Real Property

Field: Social Sciences (Social Sciences)

The basic elements of a cadastre are the definition of identified parcels on maps and the related registers of data about them. In a fiscal cadastre, the parcel should be used for only one purpose. The principle of speciality requires that one parcel designation can apply to only one parcel. There are several common designation systems. Multipurpose cadastres are being developed for many purposes other than the traditional fiscal and juridical tasks. Land tax, an important revenue source for a developing state, becomes less important as the economy expands and diversifies. Assessment data are valuable for purposes other than property taxes and should be in the cadastre. There are a number of methods of assessing property, and there can be several different but valid valuations for a single property. Governments can simplify assessment by adopting standard rules.
Controlled School Choice with Soft Bounds and Overlapping Types

Field: Decision Sciences (Social Sciences)

School choice programs are implemented to give students/parents an opportunity to choose the public school the students attend. Controlled school choice programs need to provide choices for students/parents while maintaining distributional constraints on the composition of students, typically in terms of socioeconomic status. Previous works show that setting soft-bounds, which flexibly change the priorities of students based on their types, is more appropriate than setting hard-bounds, which strictly limit the number of accepted students for each type. We consider a case where soft-bounds are imposed and one student can belong to multiple types, e.g., financially-distressed and minority types. We first show that when we apply a model that is a straightforward extension of an existing model for disjoint types, there is a chance that no stable matching exists. Thus we propose an alternative model and an alternative stability definition, where a school has reserved seats for each type. We show that a stable matching is guaranteed to exist in this model and develop a mechanism called Deferred Acceptance for Overlapping Types (DA-OT). The DA-OT mechanism is strategy-proof and obtains the student-optimal matching within all stable matchings. Furthermore, we introduce an extended model that can handle both type-specific ceilings and floors and propose a extended mechanism DA-OT* to handle the extended model. Computer simulation results illustrate that DA-OT outperforms an artificial cap mechanism where we set a hard-bound for each type in each school. DA-OT* can achieve stability in the extended model without sacrificing students welfare.
A Book Review of Animal Spirits

Field: Economics, Econometrics and Finance (Social Sciences)

On balance, this book is right. Much of modern macroeconomics is not very helpful in understanding the behaviour of financial markets and the interaction between the financial sector and the real economy. However, I am not persuaded that injecting the notion of ‘animal spirits’, even in the ways suggested, is going to improve this situation very significantly. Thus, in the last chapter, there is a sustained attack on conventional economic theories via the things they exclude. Such exclusions include changing patterns and modes of doing business; trust and confidence; corruption; stories that interpret the role of the economy. I exclude the sense of fairness from the authors’ list because there are, in fact, numerous conventional economic theories that include this and many other, probably more important, factors which inhibit wage and price flexibility. What is missing from the book is much in the way of advice on how these exclusions can be incorporated into a macroeconomic model which can then be used to answer questions like ‘what should be the capitalisation of banks?’ This is just one from the long list of questions on the penultimate page of the book. It might have been helpful if the authors had selected one of these questions and presented two answers, one taking account of animal spirits, one taking no such account.
Herbal compound Teng‑Long‑Bu‑Zhong‑Tang inhibits metastasis in human RKO colon carcinoma

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Metastasis is one of the primary obstacles to the successful treatment of colorectal cancer. Teng-Long-Bu-Zhong-Tang (TLBZT) is a modern Chinese herbal formula that may be useful in the treatment of metastatic colorectal cancer. The present study evaluated the effects of TLBZT on lung metastasis in human RKO colon carcinoma cells injected into mice via the tail vein. The results demonstrated that TLBZT inhibited the metastasis of human RKO colon carcinoma cells to the lungs. TLBZT downregulated the expression of LOX and hypoxia-inducible factor 1α. TLBZT also inhibited the expression of integrins αV and β3 and the phosphorylation of focal adhesion kinase. These results indicate that TLBZT inhibits the lung metastasis of RKO colon carcinoma by regulating the expression of multiple genes. The results of the present study provide a new basis for the management of colorectal cancer metastasis using treatments derived from Chinese herbs.
Reconsidering the limited role of right heart catheterization on severe pulmonary hypertension-due to progressive interstitial lung disease in young male patient : a case report

Field: Medicine (Health Sciences)

Pulmonary hypertension (PH)-associated with interstitial lung disease (ILD) develops as a consequence of progressive underlying lung disease or disproportionately to the underlying disease. The PH investigation by right heart catheterization (RHC) for defining PH severity is recommended in patients with ILD who show more severe symptoms than expected from lung disease, appearance of right heart failure, and clinical deterioration not matched by the declining lung function. In patient with progressive ILD, RHC is only considered if it affects the future treatment such as lung transplantation or enrollment in clinical trial/registry. The decision to undertake the RHC in progressive ILD was still fraught with doubts. Here we reported a young adult male patient with ILD whom developed progressive signs and symptoms. By RHC, he had severe precapillary PH with hemodynamic parameters indicated the presence of pulmonary vascular disease. A PH-specific treatment, sildenafil citrate, was administered, and patient responded well and was clinically stable during the addition of sildenafil citrate. This case highlights the clinical implication of performing RHC in progressive ILD, which can change the treatment decision by PH-specific drugs. Therefore, the RHC decision making in patient with progressive ILD need reconsideration.
A Manual for Conducting Even Start Program Evaluations

Field: Social Sciences (Social Sciences)

Project Even Start is an intergenerational literacy project that promotes adult literacy, trains parents to support the educational growth of their children, and prepares children for school. The program is designed to facilitate joint participation by parents and children. It includes home-based instruction and child care, and it is integrated within a network of relevant support services such as Head Start, volunteer literacy programs, and legislation such as the Adult Education Act, the Education of the Handicapped Act, and the Job Training Partnership Act. This manual was developed to train Even Start administrators and staff in assessing the effectiveness of their programs. The manual addresses the major components of the evaluation process: (1) definition of literacy and program evaluation; (2) general evaluation methods, concepts, and guidelines; (3) important procedures to follow when conducting a program evaluation; (4) tests and measurement instruments that can be used; (5) general guidelines for recording, storing, and analyzing program effectiveness data; (6) guidelines for documenting the results of the program evaluation, including constructing graphs and tables and writing program evaluation reports; (7) a description of how evaluation results can inform program planning; and (8) an annotated list of resources relating to family literacy program evaluation including 29 books and articles, 9 publishers of tests and measurement instruments, and 11 literacy organizations. (KC) *********************************************************************** Reproductions supplied by EDRS are the best that can be made from the original document. *********************************************************************** A Manual for Conducting Even Start Program Evaluations Donald J. Polzella, Ph.D. Mark A. Fine, Ph.D.