jimnoneill/paper-to-field-training huggingface dataset:
Coagulase-negative Staphylococci – A True Pathogen in Bloodstream Infections and their Resistance Patterns in a Tertiary Care Hospital

Field: Medicine (Health Sciences)

Coagulase-negative staphylococci (CoNS) are primary skin commensals that have long been considered contaminants even when grown in blood cultures. This group of organisms has been recently recognized as a potential causative pathogen of septicemia. This increase has been attributed to the increased use of intravascular and prosthetic devices. Hence, we aimed to estimate the prevalence of CoNS as a true pathogen in adult and pediatric blood cultures along with their antibiotic susceptibility patterns. A total of 1076 adult and 611 pediatric blood cultures were subjected to an automated BacT/ALERT continuous monitoring system. Isolated CoNS were considered true pathogens if they met the diagnostic, clinical, and laboratory criteria. Antimicrobial susceptibility testing for pathogenic CoNS was carried out using the Kirby-Bauer disk diffusion method and interpreted as per CLSI 2021. CoNS were considered true pathogens in 23 (42.5%) of 54 adults and 12 (41.3%) of 29 pediatric CoNS isolated from blood cultures. Methicillin-resistant CoNS was detected in 66% and 70% of adult and pediatric cultures, respectively. All the CoNS isolates were sensitive to vancomycin and linezolid. Coagulase-negative staphylococci (CoNS) can either be a contaminant or a true pathogen, whose discrimination based on clinical and laboratory indices plays a pivotal role in the management of patients with sepsis.
Differences in Pelvic Morphology Between Women with and Without Provoked Vestibulodynia

Field: Medicine (Health Sciences)

ABSTRACT Objective Pelvic morphology has been suggested to reflect increased tone and reduced strength of the pelvic floor muscles (PFMs) in women with provoked vestibulodynia (PVD) compared to healthy controls. We aimed to determine whether there are differences in pelvic morphology in the resting state, on maximum voluntary contraction (MVC), or on maximum effort Valsalva maneuver (MVM) between women with and without PVD. Methods While imaged using ultrasound, 38 women with PVD and 39 controls relaxed their PFMs, performed 3 MVCs and performed 3 MVMs. Levator plate length (LPL), levator plate angle (LPA), and anorectal angle (ARA) were determined at rest, at MVC and at MVM. The displacement of the bladder neck (BN) on MVC and on MVM was also determined. Two-way ANCOVAs were used to evaluate the main effects of group and task, the interaction between group and task, and the effect of resting morphology on LPL, LPA, and ARA. A 2-way repeated-measures ANOVA was used to determine whether the groups differed in terms of BN displacement during the tasks. Results Women with PVD had smaller LPLs and LPAs than controls across all tasks. The significant group differences in LPL and LPA at MVC and MVM were no longer significant once the resting values were included as covariates in the models. Bladder neck displacement differed between the groups at MVM but not at MVC. Conclusion Women with PVD display shorter LPL sand smaller LPAs than controls but their behavior does not differ when MVC and MVMs are performed. Our results do not support the hypothesis that women with PVD demonstrate abnormalities in PFM contractility on MVC or compliance on MVM.
Research on programmed operation of power grid equipment based on Natural Language Processing

Field: Computer Science (Physical Sciences)

With the expanding of State Grid structure, operation instructions logics of power grid are increasingly complex, which makes it even more difficult to compile operation instructions based on the dispatchers' experiences, consequently may lead to great risks in safe running of the power grid. This paper proposes an artificial intelligence method adopting NLP (Natural Language Processing) technology, this method can get the computers understand power grid operation tasks by themselves and automatically generate operation instructions with the deduction method designed by the authors. To reduce the dispatchers' workload and to improve the accuracy and safety of operations, these instructions need to be checked for safety before and after execution.
Anxiety is Not Manifested by Elevated Heart Rate and Blood Pressure in Acutely Ill Cardiac Patients

Field: Medicine (Health Sciences)

Elevated heart rate and blood pressure do not accurately reflect level of anxiety as reported by patients with HF or AMI and healthy individuals, and thus cannot be used to assess anxiety in acutely ill patients. Clinicians who use changes in heart rate or blood pressure as indicators of anxiety may fail to recognize and treat anxiety, placing their patients at high risk for both immediate and long-term complications.
The Boys and Girls of Summer: The University of New Mexico Archaeological Field School in Chaco Canyon

Field: Arts and Humanities (Social Sciences)

Field training for archaeological students at the University of New Mexico began in 1929 when Edgar L. Hewett established a camp in Chaco Canyon. For a total of fifteen seasons, it trained students--many of them women--who later made important contributions to anthropology. This study of the politics, personnel, and fieldwork of the Chaco field school discusses its impact on scholarship, its role in preparing professional archaeologists, and its relationships with several New Mexico institutions such as the School of American Research.
COMPOSITE MATERIAL DIAPHRAGM ARRAYS FOR MECHANOBIOLOGICAL STIMULATION OF CULTURED CELLS

Field: Materials Science (Physical Sciences)

This paper reports on a novel device array designed with composite materials intended to enhance cell adhesion to a mechanically active substrate, while maintaining the mechanical properties and fabrication advantages of using PDMS microdevices. Layered polyurethane-PDMS films are suspended over a cavity and distended by the application of a cyclic pressure waveform. The resulting deformation is characterized. Significant improvements in adhesion of primary cells to mechanically active substrates are demonstrated.
Performance evaluation and improvement of deep Q network for lunar landing task

Field: Computer Science (Physical Sciences)

Reinforcement learning is now being applied more and more in a variety of scenarios, the majority of which are based on the deep Q network (DQN) technology. However, the algorithm is heavily influenced by multiple factors. In this paper, we take the lunar lander as a case to study how various hyper-parameters affect the performance of the DQN algorithm, based on which we tune to get a model with better performance. At present, it is known that the DQN model has an average reward of 280+ on 100 test episodes, and the reward value of the model in this article can reach 290+. Meanwhile, its robustness is tested and verified by introducing additional uncertainty tests into the original problem. In addition, to speed up the training process, imitation learning is incorporated in our model, using heuristic function model guidance method to obtain demonstration data, which accelerates training speed and improves performance. Simulation results have proven the effectiveness of this method.
Opacity effects on the radiative losses of coronal loops

Field: Physics and Astronomy (Physical Sciences)

view Abstract Citations (29) References (29) Co-Reads Similar Papers Volume Content Graphics Metrics Export Citation NASA/ADS Opacity Effects on the Radiative Losses of Coronal Loops Kuin, N. P. M. ; Poland, A. I. Abstract This paper presents calculations of radiative losses, which include the effects of geometry and optical depth, that can be used to improve the energy losses in many flux-tube calculations for loops with constant and variable cross sections. The results include the non-LTE ionization state of hydrogen and helium, thus allowing the determination of the ionization energy in the gas and the relative importance of collisional and radiative processes. These calculations show that optical depth effects are important under solar conditions in the temperature range of 8000-40,000 K. Publication: The Astrophysical Journal Pub Date: April 1991 DOI: 10.1086/169859 Bibcode: 1991ApJ...370..763K Keywords: Coronal Loops; Opacity; Radiative Transfer; Solar Flares; Solar Prominences; Computerized Simulation; Magnetohydrodynamics; Optical Thickness; Stellar Models; Solar Physics; RADIATIVE TRANSFER; SUN: CORONA; SUN: FLARES; SUN: PROMINENCES full text sources ADS |
Chewing rates among domestic dog breeds

Field: Neuroscience (Life Sciences)

The mammalian masticatory rhythm is produced by a brainstem timing network. The rhythm is relatively fixed within individual animals but scales allometrically with body mass (Mb) across species. It has been hypothesized that sensory feedback and feed-forward adjust the rhythm to match the jaw's natural resonance frequency, with allometric scaling being an observable consequence. However, studies performed with adult animals show that the rhythm is not affected by jaw mass manipulations, indicating that either developmental or evolutionary mechanisms are required for allometry to become manifest. The present study was performed to tease out the relative effects of development versus natural selection on chewing rate allometry. Thirty-one dog breeds and 31 mass-matched non-domestic mammalian species with a range in Mb from ∼2 kg to 50 kg were studied. Results demonstrated that the chewing rhythm did not scale with Mb among dog breeds (R=0.299, P>0.10) or with jaw length (Lj) (R=0.328, P>0.05). However, there was a significant relationship between the chewing rhythm and Mb among the non-domestic mammals (R=0.634, P<0.001). These results indicate that scaling is not necessary in the adult animal. We conclude that the central timing network and related sensorimotor systems may be necessary for rhythm generation but they do not explain the 1/3rd to 1/4th allometric scaling observed among adult mammals. The rhythm of the timing network is either adjusted to the physical parameters of the jaw system during early development only, is genetically determined independently of the jaw system or is uniquely hard-wired among dogs and laboratory rodents.
An infectious mononucleosis-like syndrome induced by minocycline: a third pattern of adverse drug reaction.

Field: Medicine (Health Sciences)

A 22-year-old black man developed fever, chills, fatigue, night sweats, tender lymphadenopathy, and a generalized, pruritic, macular eruption 3 weeks after starting minocycline therapy for acne. His illness was also characterized by a palpable spleen tip, marked lower extremity and scrotal edema, and generalized lymphadenopathy. The patient had leukocytosis with a large percentage of atypical lymphocytes on peripheral smear and liver dysfunction. Titers for Epstein-Barr virus, hepatitis B, toxoplasmosis; and cytomegalovirus were all negative. Human immunodeficiency virus-1 viral load and antibodies were also negative. Marked improvement was noted after the discontinuation of minocycline and the use of systemic corticosteroids. With the negative viral serologies, the clinical picture was most consistent with an infectious mononucleosis-like syndrome produced by the minocycline ingestion.
Highly sensitive and selective separation of intact parathyroid hormone and variants by sheathless CE‐ESI‐MS/MS

Field: Chemistry (Physical Sciences)

Abstract Parathyroid hormone (PTH) is a common clinical marker whose quantification relies on immunoassays, giving variable results as batch, brand, or target epitope changes. Sheathless CE‐ESI‐MS, combining CE resolution power and low‐flow ESI sensitivity, was applied to the analysis of PTH in its native conformation in the presence of related forms. Fused silica and neutral‐coated capillaries were investigated, as well as preconcentration methods such as transient isotachophoresis, field‐amplified sample injection (FASI), and electrokinetic supercharging (EKS). The method for the separation of PTH and its variants was first developed using fused‐silica capillary with UV detection. An acidic BGE was used to separate 1–84 PTH (full length), 7–84 PTH, and 1–34 PTH. Acetonitrile was added to the BGE to reduce peptide adsorption onto the capillary wall and transient isotachophoresis was used as analyte preconcentration method. The method was then transferred to a sheathless CE‐ESI‐MS instrument. When using a fused silica capillary, CE‐MS was limited to μg/mL levels. The use of a neutral coating combined with FASI or EKS allowed a significant increase in sensitivity. Under these conditions, 1–84 PTH, 7–84 PTH, and 1–34 PTH were detected at concentrations in the low ng/mL (FASI) or pg/mL (EKS) range.
Topology and Chirality

Field: Physics and Astronomy (Physical Sciences)

Topology, a well-established concept in mathematics, has nowadays become essential to describe condensed matter. At its core are chiral electron states on the bulk, surfaces and edges of the condensed matter systems, in which spin and momentum of the electrons are locked parallel or anti-parallel to each other. Magnetic and non-magnetic Weyl semimetals, for example, exhibit chiral bulk states that have enabled the realization of predictions from high energy and astrophysics involving the chiral quantum number, such as the chiral anomaly, the mixed axial-gravitational anomaly and axions. The potential for connecting chirality as a quantum number to other chiral phenomena across different areas of science, including the asymmetry of matter and antimatter and the homochirality of life, brings topological materials to the fore.
Low-Dose Aspirin and Vitamin E

Field: Medicine (Health Sciences)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Of mushrooms and method: History and the family in Hobbes’s science of politics

Field: Arts and Humanities (Social Sciences)

Hobbes’s account of the commonwealth is standardly interpreted to be primarily a theory of contract, whereby the archetypal manner of forming a political community is via an act of mutual agreement between suspicious individuals of equal power. By examining Hobbes’s theories of the pre-political family, and what he says about the role of real history in the development of political societies, I conclude that this standard interpretation is untenable. Rather, Hobbes’s conception of commonwealth ‘by institution’ is a hypothetical model used to illustrate the mechanics of sovereignty, and to reconcile men to the conditions of subjection to absolute political power. In practice, all sovereignty is originally by ‘acquisition’. Realizing this casts serious doubt on the possibility that Hobbes is a fundamentally democratic thinker. In turn, we are invited to reconsider the history of political thought after Hobbes, in particular by seeing his theory of the family and of history as a genealogical ancestor of Scottish Enlightenment political theory.
Supervised Learning of Human Welder Behaviors for Intelligent Robotic Welding

Field: Computer Science (Physical Sciences)

Current industrial welding robots are mostly articulated arms with a pre-programmed set of movement, which lack the intelligence skilled human welders possess. In this paper, human welder's response against 3-D weld pool surface is learned and transferred to the welding robots to perform automated welding tasks. To this end, an innovative teleoperated virtualized welding platform is utilized to conduct dynamic training experiments by a human welder whose arm movements together with the 3-D weld pool characteristic parameters are recorded. The data is off-line rated by the welder and a fuzzy classifier is trained, using an adaptive neuro-fuzzy inference system (ANFIS), to automate the rating. Data from the training experiments are then automatically classified such that top rated data pairs are selected to model and extract “good response” minimizing the effect from “bad operation” made during the training. A supervised ANFIS model is then proposed to correlate the 3-D weld pool characteristic parameters and welder's adjustment on the welding speed. The obtained model is then transferred to the welding robot to perform automated welding task as an intelligent controller. Experiment results verified that the proposed model is able to control the process under different welding current as well as under disturbances in speed and measurement. A foundation is thus established to selectively learn “good response” to rapidly extract human intelligence to transfer into welding robots.
A FERM domain governs apical confinement of PTP-BL in epithelial cells

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

ABSTRACT PTP-BL is a cytosolic multidomain protein tyrosine phosphatase that shares homologies with several submembranous and tumor suppressor proteins. Here we show, by transient expression of modular protein domains of PTP-BL in epithelial MDCK cells, that the presence of a FERM domain in the protein is both necessary and sufficient for its targeting to the apical side of epithelial cells. Furthermore, immuno-electron microscopy on stable expressing MDCK pools, that were obtained using an EGFP-based cell sorting protocol, revealed that FERM domain containing fusion proteins are enriched in microvilli and have a typical submembranous location at about 10-15 nm from the plasma membrane. Immunofluorescence microscopy suggested colocalization of the FERM domain moiety with the membrane-cytoskeleton linker ezrin. However, at the electron microscopy level this colocalization cannot be confirmed nor can we detect a direct interaction by immunoprecipitation assays. Fluorescence recovery after photobleaching (FRAP) experiments show that PTP-BL confinement is based on a dynamic steady state and that complete redistribution of the protein may occur within 20 minutes. Our observations suggest that relocation is mediated via a cytosolic pool, rather than by lateral movement. Finally, we show that PTP-BL phosphatase domains are involved in homotypic interactions, as demonstrated by yeast two-hybrid assays. Both the highly restricted subcellular compartmentalization and its specific associative properties may provide the appropriate conditions for regulating substrate specificity and catalytic activity of this member of the PTP family.
Is Psalm 110 Canaanite?

Field: Arts and Humanities (Social Sciences)

Research Article| September 01 1954 Is Psalm 110 Canaanite? Helen Genevieve Jefferson Helen Genevieve Jefferson Search for other works by this author on: This Site Google Journal of Biblical Literature (1954) 73 (3): 152–156. https://doi.org/10.2307/3261728 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Permissions Cite Icon Cite Search Site Citation Helen Genevieve Jefferson; Is Psalm 110 Canaanite?. Journal of Biblical Literature 1 September 1954; 73 (3): 152–156. doi: https://doi.org/10.2307/3261728 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All Scholarly Publishing CollectiveSBL PressJournal of Biblical Literature Search Advanced Search The text of this article is only available as a PDF. Article PDF first page preview Close Modal You do not currently have access to this content.
Yan Family 1734–1780s

Field: Economics, Econometrics and Finance (Social Sciences)

The Yan family was very important to the growth of the Canton trade. Texia and Simon took the business by storm in 1734, and within two years were in control of the lion's share. They quickly gained the confidence of all the foreign companies, and became one of the most respected and responsible houses in the trade. By sending their own agents into China's interior, the Yans gained better control over quality and quantities; by maintaining their own fleet of junks, they were able to ensure that adequate supplies of input goods arrived each year to keep the foreign trade moving forward; and by having a relative, Hongsia, closely involved with both the foreigners and junks at the same time, the family had resources that few other houses in Canton could match.
Clinical and molecular analysis of human reproductive disorders in Brazilian patients

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Several genes that influence the development and function of the hypothalamic-pituitary-gonadal-axis (HPG) have been identified. These genes encode an array of transcription factors, matrix proteins, hormones, receptors, and enzymes that are expressed at multiple levels of the HPG. We report the experience of a single Endocrinology Unit in the identification and characterization of naturally occurring mutations in families affected by HPG disorders, including forms of precocious puberty, hypogonadism and abnormal sexual development due to impaired gonadotropin function. Eight distinct genes implicated in HPG function were studied: KAL, SF1, DAX1, GnRH, GnRHR, FSHbeta, FSHR, and LHR. Most mutations identified in our cohort are described for the first time in literature. New mutations in SF1, DAX1 and GnRHR genes were identified in three Brazilian patients with hypogonadism. Eight boys with luteinizing hormone- (LH) independent precocious puberty due to testotoxicosis were studied, and all have their LH receptor (LHR) defects elucidated. Among the identified LHR molecular defects, three were new activating mutations. In addition, these mutations were frequently associated with new clinical and hormonal aspects, contributing significantly to the knowledge of the molecular basis of reproductive disorders. In conclusion, the naturally occurring genetic mutations described in the Brazilian families studied provide important insights into the regulation of the HPG.
Development of a Small Two Axis Spherical Motor Type Laser Tracker with Submicron Measurement Accuracy

Field: Engineering (Physical Sciences)

Recently, it is in great need for measurement of the three dimensional surface form of the car and the aircraft, the path of the industrial robot and the machine tool, and so on with a high degree of accuracy. We have proposed a novel laser tracking three dimensional position measurement system which can measure the 3D position with submicron accuracy at more than 1[m] by combining the oscillating lever mechanism with the spherical motor. Before making the full system, we made the first and the second prototype spherical motor type laser tracker unit and tested them. The average measurement error of the developed laser tracker 2 is 0.45[μm] and the standard deviation is 0.54[μm], which satisfy the specifications needed for the full system.