jimnoneill/paper-to-field-training huggingface dataset:
REVITALIZATION OF TOLERANCE VALUES THROUGH LOCAL CULTURAL TRADITIONS EFFORTS TO PRESERVE LOCAL CULTURE IN THE YOUNG GENERATION IN THE TRADITIONAL GAME OF CONGKLAK

Field: Social Sciences (Social Sciences)

Revitalizing tolerance values through local cultural traditions is essential in preserving local culture among the younger generation. This article explores the role of traditional games, particularly congklak, as a medium to instill tolerance and social harmony. Congklak, a traditional Indonesian game rich in historical and cultural significance, teaches important values such as patience, cooperation, and mutual respect. By integrating these values into the game’s practice, it becomes a strategic tool for fostering cultural awareness and strengthening communal bonds. This study highlights how local traditions like congklak can be revitalized to address the erosion of cultural identity in the modern era. It also emphasizes the importance of involving youth in cultural preservation efforts to ensure the sustainability of Indonesia’s intangible heritage. Through an interdisciplinary approach combining cultural studies and education, this article advocates for the incorporation of traditional games into formal and informal education systems as a means of cultivating tolerance and preserving local cultural traditions
The optimisation of conditions for the extraction of banana juice with a pectolytic enzyme preparation

Field: Chemical Engineering (Physical Sciences)

The aim of the work was the optimisation of conditions\nfor the extraction of juice from surplus bananas using\npectolytic enzymes. Juice extracted in this way could be\n'used to make other products, e.g. beverages, wine, vinegar.\nBananas were supplied by Geest Industries Ltd., and were\nof known history and variety (Cavendish). The sample~\nw'ere allowed to ripen under controlled conditions of\ntemperature and relative humidity, and were enzyme-treated\nat the same degree of ripeness as determined by sugar\ncontent (18.0 + 0.3% w/w).....
Routine universal screening for Lynch syndrome in colorectal cancer patients in the community setting.

Field: Medicine (Health Sciences)

1512 Background: Identification of colorectal cancer (CRC) cases that are due to Lynch Syndrome (LS) is important to prevent secondary malignancies or development of additional malignancies among relatives. Utilization of clinical criteria to select CRC patients for laboratory testing fails to identify a significant proportion of patients whose CRC is due to LS. Therefore, universal screening for LS among CRC patients has been advocated by the Evaluation of Genomic Applications in Practice and Prevention Working Group. However, the feasibility of routine universal screening has not been evaluated in a community-based, non-research setting. We implemented a universal screening protocol for LS as part of routine care of CRC at Norton Healthcare, a multi-institutional community-based healthcare organization. Methods: Beginning in October 2009, all resected CRC tumors automatically underwent immunohistochemistry analysis (IHC) for Lynch Syndrome-associated mismatch repair gene (MMR) expression. Selected patients who underexpressed MLH1 also underwent testing for the BRAF V600E mutation. Patients who had a BRAF V600E mutation were considered to have sporadic CRC. All other patients with abnormal IHC were automatically referred for genetic counseling. We retrospectively reviewed the outcomes of genetic counseling in all patients referred through this universal screening protocol. Results: Between October 2009 and December 2011, 388 patients underwent resection of CRC, all of whom had IHC for MMR expression. Seventy patients were identified as having abnormal IHC. Sixty-two had MLH1/PMS2 underexpression, of which 18 underwent BRAF testing and 13 had a BRAF V600E mutation. Eight had MSH2/MSH6 underexpression. Nine patients have been confirmed to have LS, 31 have been found not to have LS, and 19 are in the process of evaluation. Seven patients declined genetic counseling, and 4 died before they could be adequately evaluated. Conclusions: Universal screening for CRC due to LS, using IHC with select BRAF V600E mutation testing and automated referral for genetic counseling, is feasible in the community setting. Funded in part with federal funds: NCI, NIH, Contract No. HHSN261200800001.
BORDER-BASED MANAGEMENT AT MADRASAH IBTIDAIYAH IN SEBATIK, NORTH KALIMANTAN

Field: Social Sciences (Social Sciences)

Educational institutions have an essential role to play in dealing with border issues. Madrasah Ibtidaiyah Darul Furqon uses border issues to develop the governance of educational institutions. This research focuses on two things. First, what are the characteristics of border-based Islamic Elementary Education management at Madrasah Ibtidaiyah Darul Furqon? Second, how is the strength of the management in its participation in responding to border issues? Research with this qualitative method collects data through observation, interviews, and documentation. The analysis uses three stages: data reduction and presentation, and conclusion. This Madrasah has utilized school-based management to develop border-based Islamic Elementary Education Management. Among the characteristics of border issues concerning its management is branding as the Boundary School, the orientation of student recruitment by taking community groups with problems in border areas as its customer segments, and management of learning management based on border issues. The use of management like this gives strength to this Madrasah to manage aspects of the customer segment, value proposition, channel, key partnerships, key activities, and cost structure in the business management of educational institutions to deal with border issues. This Madrasah also utilizes management like this to develop inclusive Islamic religious education in the border context.
Prognostic utility of blood pressure-adjusted global and basal systolic longitudinal strain

Field: Medicine (Health Sciences)

Assessment of global longitudinal systolic strain (GLS) and longitudinal systolic strain of the basal segments (BLS) has shown prognostic value in cardiac disorders. However, strain is reduced with increased afterload. We assessed the prognostic value of GLS and BLS adjusted for afterload. GLS and BLS were determined in 272 subjects with normal ejection fraction and no known coronary disease, or significant valve disease. Systolic blood pressure (SP) and diastolic blood pressure (DP) obtained at the time of echocardiography were used to adjust GLS and BLS as follows: strain×SP (mmHg)/120 mmHg and strain×DP (mmHg)/80 mmHg. Patients were followed for cardiac events and mortality. The mean age was 53±15 years and 53% had hypertension. There were 19 cardiac events and 70 deaths over a mean follow-up of 26±14 months. Cox analysis showed that left ventricular mass index (P=0.001), BLS (P<0.001), and DP-adjusted BLS (P<0.001) were independent predictors of cardiac events. DP-adjusted BLS added incremental value (P<0.001) to the other two predictors and had an area under the curve of 0.838 for events. DP (P=0.001), age (P=0.001), ACE inhibitor use (P=0.017), and SP-adjusted BLS (P=0.012) were independent predictors of mortality. SP-adjusted BLS added incremental value (P=0.014) to the other independent predictors. In conclusion, DP-adjusted BLS and SP-adjusted BLS were independent predictors of cardiac events and mortality, respectively. Blood pressure-adjusted strain added incremental prognostic value to other predictors of outcome.
EasyABM: a lightweight and easy to use heterogeneous agent-based modelling tool written in Julia.

Field: Computer Science (Physical Sciences)

Agent based modelling is a computational approach that aims to understand the behaviour of complex systems through simplified interactions of programmable objects in computer memory called agents. Agent based models (ABMs) are predominantly used in fields of biology, ecology, social sciences and economics where the systems of interest often consist of several interacting entities. In this work, we present a Julia package EasyABM.jl for simplifying the process of studying agent based models. EasyABM.jl provides an intuitive and easy to understand functional approach for building and analysing agent based models.
Solid tumor models for the assessment of different treatment modalities XII. Combined chemotherapy-radiotherapy: Variation of time interval between time of administration of 5-fluorouracil and radiation and its effect on the control of tumor growth

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The combined effects of radiation and 5-fluorouracil (5-FU) on control of tumor growth rates in the experimental solid tumor 3924A have been determined when radiation (1500 rads) was given 14, 7, 4, 2, 1 and 0.5 days before 5-FU (150 mg/kg); and 1, 2, 4, 7, 11, and 15 days after 5-FU. These results were compared to single doses of each modality given alone and both modalities given simultaneously. Two methods of evaluation were utilized, tumor growth delay and “overall treatment efficiency.” The widely used method of tumor growth delay indicates that the combined effect of radiation and 5-FU significantly increased tumor growth delay over the additive effect of the two modalities given independently for schedules in which radiation was given from 4 days prior to 2 days after 5-FU. Maximum tumor growth delay occurred when radiation was given 4 days before 5-FU; being 2.5 times the additive effects of each modality. Separation of the administration of radiation and 5-FU by ± 7 to 14 days resulted in two distinct perturbations in tumor growth curves and was less effective than when the two agents were given at shorter intervals. The term “overall treatment efficiency”(OTE) has been introduced to determine the magnitude of tumor volume changes following treatment. The OTE indicates that maximum tumor volume reduction also occurred when radiation was given 4 days before 5-FU. OTE was 1.5 times the additive effect of the two modalities given independently at this time. Radiation given 4 days after 5-FU gave less than additive responses, with tumor growth delay and OTE for this combination of 5-FU and radiation being 0.8 and 0.6 of the additive effects, respectively. The effects of combining radiation with 5-FU did not reduce animal survival below the survival level of the group given 5-FU alone in 8 of 10 groups evaluated. Cancer 44:437-445, 1979.
Efficiency Enhancement of an Unstructured CFD-Code on Distributed Computing Systems

Field: Computer Science (Physical Sciences)

In this paper we describe several improvements with respect to parallel efficiency and scalar performance of unstructured CFD-Codes. The optimizations are genericin the sense that they are applicable to any CFD-Code which works on unstructured grids. The code modifications were sucessively introduced in the DLR TAU-Code and the results of the optimizations are demonstrated on two different aircraft configurations. We give an outlook of further improvements with respect to upcoming multicore computing architectures.
Growth rate of broiler chickens is influenced by early life feeding strategy

Field: Agricultural and Biological Sciences (Life Sciences)

After hatching in conventional systems, broiler chickens have a delay to nutrition thatcan last for 72h, depending on length of the hatch window, internal hatchery proceduresand transport duration. Previous research on early life feeding strategies has shownnegative effects on bodyweight (BW) gain after delayed nutrition (DN), compared withearly nutrition (EN). However, it is not known whether DN chickens can (partially)compensate for their lower BW between hatch and slaughter. In this study, we tested thehypothesis that DN chickens have an increased growth rate, as a result of compensatorygrowth. Data from 3 independent experiments were used. In these studies, broilerswere subjected to either EN or DN with different durations of DN (38 to 72 h) and daysto slaughter (14 to 35 d). In all experiments, DN groups had lower BW compared withEN which was sustained until slaughter. Relative differences in BW, however, decreasedfrom 114 to 176% post placement to 102 – 112 % at slaughter (35 d). Growth curves of DNand EN chickens were analysed to study whether compensatory growth could explain thedifferences in BW between EN and DN. Absolute average daily gain (aADG) was higher inEN chickens from start until slaughter. To analyse the growth curve independent of BW,relative ADG (rADG) between two ages was calculated as follows:Differences in rADG between DN and EN chickens were greater in the first 14 d (DN:63%, EN: 47%; P < 0.001), but smaller in the remaining grow-out period (14 – 28 d:DN: 18%, EN: 16%; 28 – 35 d: DN: 8%, EN: 7%; both P <0 .001). Based on these results,it seems that DN broilers compensate for their lag in BW during the first 14 d postplacement. As differences in absolute BW were still present at 35 d, the increase in rADGseems insufficient to catch up with EN broilers. EN chickens have higher aADG untilslaughter, however, rADG is lower, showing that growth rate is influenced by feedingstrategy. Previous literature describes interactions between compensatory growth andnutrient composition of diets on nitrogen and fat retention. This may give reason forfuture work to evaluate effects of early life feeding strategy on carcass traits.
A preprocessing strategy of RDF data query based on relational database

Field: Computer Science (Physical Sciences)

To improve the efficiency of the query on the data of resource description framework (RDF), the method of storage and management of the data at home and abroad is studied.According to the characteristic of the data that the number of subjects and objects is large and the number of attributes is small, a preprocessing of the storage of the data based on the relational database is proposed.The query first judge the property, and then performed, thus the efficiency of the implementation of the query is improved.Finally, the data was generated uses the LUMB data set, and then, the designed query is executed on it.The experimental results verify the validity of the method.
Investigation on vibration characteristics induced by gas–liquid two-phase flows in a horizontal pipe

Field: Engineering (Physical Sciences)

The intrinsic characteristics of multiphase flow inevitably result in vibrations within the pipe structure. The evolution of vibration characteristics is crucial for monitoring the stability of the multiphase flow pipelines. However, under high liquid velocity condition, the influence of flow pattern on the gas–liquid two-phase flow-induced vibration (GTFIV) of the pipe remains unclear. In this paper, the vibration signals in the horizontal pipe under different flow patterns at high liquid velocity are measured by a vibration test system. Synchronously, images inside the pipe are captured to illustrate the flow mechanism. The results show that the α stable distribution model holds higher fitting accuracy than the standard normal distribution for the GTFIV. The random behavior of small-scale bubbles determines the structural richness of the GTFIV. The multifractal characteristics of the GTFIV are strongly dependent on the flow pattern. The formation of the gas plug leads to significant unevenness in the fractal structure of the GTFIV. The multifractal strength of the GTFIV gradually increases as the flow pattern transforms from dispersed bubble flow to slug flow. Some multifractal spectrum parameters of the vibration signal can be applied for the identification of flow patterns in the pipe.
Group A Streptococci: Localization in Rabbits and Guinea Pigs Following Tissue Injury

Field: Medicine (Health Sciences)

Rabbits injected intravenously with extracellular products ("toxins") of group A streptococci develop myocardial, muscular, and hepatic lesions. When such animals are then challenged with fluorochrome-labeled group A streptococci or with titanium oxide particles the labeled bacteria or particles localize within phagocytic cells in the tissue lesions caused by the toxins. Similarly, labeled streptococci or titanium oxide particles will also localize within phagocytic cells in skin lesions of guinea pigs that develop delayed hypersensitivity to tuberculin or to bovine gamma globulin. It is proposed that a combined mechanism of injury and localization of bacteria in damaged tissues may be responsible for poststreptococcal sequelae or other chronic inflammatory diseases.
Evaluation and modification of solid set sprinkler system for Hirashima Berry Farms

Field: Agricultural and Biological Sciences (Life Sciences)

This project encompassed the evaluation and recommendations for a solid set sprinkler system. This project will determined the distribution uniformity for an existing solid set sprinkler system located on Hirashima Berry Farms. After the evaluation was complete modifications were suggested to the farmer in order to lower watering costs during pre-irrigation and provide salt leaching. The results from the system evaluation show that the current system distribution uniformity is 0.69. The following recommendations and conditions were assumed; normal pre-irrigation practices, an EC threshold of 2.0 dS/m for strawberries, a leaching requirements of 0.15, and an improved DU to 0.80. With these assumptions, the cost analysis demonstrates that the farmer could save about $250/year for the 12 acre plot.
ONE‐WEEK TRIPLE THERAPY FOR ERADICATION OF H. PYLORI (with ranitidine bismuth citrate, clarithromycin [250 or 500 mg] and amoxillin or tinidazole)

Field: Medicine (Health Sciences)

Objective It hasn’t enough data for the brand‐new short‐term triple therapy with ranitidin bismuth citrate (RBC) and two antibiotics. In present our aim is to evaluate the efficacy of brand‐new one‐week triple therapy (containing ranitidin bismuth citrate, Clarithromycin [CLA] and Amoxillin [AMOX] or tinidazole [TIN]) in 124 HP positive patients (PTS) (45 with active peptic ulcer and 79 with chronic antral gastritis/ulcer was in their case‐history/). Material & Method We tried to use the following drugs combinations for treatment for one week: Group RBCCA: 400 mg RBC bid, 500 mg CLA bid, 1000 mg AMOX bid, group RBCC 500 T : 400 mg RBC bid, 500 mg CLA bid, 500 mg TIN bid, group RBCC250T: 400 mg RBC bid, 250 mg CLA bid, 500 mg TIN bid, group RBCC500T: 400 mg RBC bid, 500 mg CLA bid, 500 mg TIN bid. In ulcer‐PTS 300 mg/day ranitidin treatment was applied for 3 weeks. Upper GI endoscopy was performed with histological, cultivation and/or rapid urease test (RUT) examination prior to and 6 weeks after eradication. We assessed healing rate of peptic ulcer, alteration in the activity of chronic gastritis, and tolerability of the treatment. Result 118out of 124 PTS completed the trial (drop out: 6, male: 51, aver. age: 50.28 ys, smoker: 53). Sex PTS dropped out (3 of them in consequence of side effect / diarrhoea and abdominal pain/) Complete ulcer healing was confirmed in all (41) ulcer‐PTS. HP was eradicated in 104 out of 118 PTS (PP:88.1%, ITT: 83.9%). The detailed results are shown on following chart: Group TTP Ulcer.g Gastritis. g. RBCCA RBCCA 84.88 % 88.6 % 92.9 % 86.6 % RBCC 250T 86.5 % 91.4 % 92.3 % 81.8 % RBCC 500T 80.5 % 84.6 % 78.6 % 88 % The drug regimen was very well tolerated (only in 11 cases [8.9 %] they were side effects: nausea, pyrosis, headache and diarrhoea). Conclusion All of the one‐week triple therapy (cont.RBC) was as effective to eradicate HP as the other triple therapies. The short duration and few side effects ensure the compliance of the PTS.
SRG/eROSITA view of X-ray reflection in the Central Molecular Zone: a snapshot in September–October 2019

Field: Physics and Astronomy (Physical Sciences)

ABSTRACT X-ray reflection off dense molecular clouds in the Galactic Centre region has established itself as a powerful probe for the past activity record of the supermassive black hole Sgr A* on a time-scale of a few hundred years. Detailed studies of the reflection signal from individual clouds allow us to estimate parameters of the brightest flare(s) and explore properties of the dense gas distribution inside and around them. On the other hand, wide-area surveys covering the full Central Molecular Zone (CMZ) are crucial to spot the brightening of the new clouds and long-term decay of the flux from the once bright ones. Here, we present and discuss the data obtained by the SRG/eROSITA telescope in the course of its commissioning observations in late 2019 in regard to the X-ray reflection off CMZ clouds located to the East of Sgr A*. We measure the hard X-ray (4–8 keV) flux from the currently brightest (in reflected emission) molecular complex, Sgr A, and derive upper limits for other molecular complexes. We confirm that the Sgr A complex keeps being bright at the level of $4\times 10^{-13}\,{\rm erg\, s^{-1}\,cm^{-2}\,arcmin^{-2}}$, making it an excellent candidate for the deep forthcoming high-resolution imaging and polarimetric observations. We also discuss distinct features of the reflected emission from the clouds for which the primary illumination front has already passed away and the signal is dominated by multiply scattered radiation.
Extragalactic relativistic jets

Field: Physics and Astronomy (Physical Sciences)

Abstract Relativistic jets are one of the most powerful manifestations of the release of energy produced around supermassive black holes at the centre of active galactic nuclei (AGN). Their emission is observed across the entire electromagnetic spectrum, from the radio band to gamma rays. Despite decades of efforts, many aspects of the physics of relativistic jets remain elusive. In particular, the location and the mechanisms responsible for the high-energy emission and the connection of the variability at different wavelengths are among the greatest challenges in the study of AGN. Recent high resolution radio observations of flaring objects locate the high energy emitting region downstream the jet at parsec scale distance from the central engine. Furthermore, monitoring campaigns of the most active blazars indicate that not all the high energy flares have the same characteristics in the various energy bands, even from the same source, making the interpretation of the mechanism responsible for the high-energy emission not trivial. Here I will discuss gamma-ray properties of blazars obtained by Fermi Large Area Telescope observations and the connection between radio and high-energy emission in relativistic jets, and I will focus on the importance of high angular resolution observations.
[Early adjuvant intraportal chemotherapy with 5-fluorouracil after hepatic resection of colorectal metastasis: a preliminary clinical and pharmacokinetic study].

Field: Medicine (Health Sciences)

Intraportal continuous infusion of 5-FU (600 mg/m2/24 h during 7 days) was administered in the immediate postoperative course of 6 consecutive patients with colorectal metastases resected for cure (one segmentectomy and 5 nonanatomical local resections). One month later, a systemic continuous infusion of 5-FU was delivered at the same dose. The tolerance of intraportal chemotherapy was good despite 2 patients with mild digestive toxicity. The plasma concentrations of both unchanged 5-FU and 5,6-dihydro-5-FU (the primary metabolite of 5-FU), were determined in 2 patients using Gas Chromatography--Mass Spectrometry. The 5-FU clearance was higher after intraportal infusion than after systemic infusion (x 1.5 to 3). Hepatic extraction was variable (0.32-0.70) and lower than in reported experimental data on dogs (0.90-0.99). 5,6-dihydro-5-FU concentrations were constantly higher than 5-FU concentrations in plasma. The patient with lower hepatic extraction had the higher 5,6-dihydro-5-FU plasma concentrations. These findings suggest a predominant extrahepatic formation of plasmatic 5,6-dihydro-5-FU.