jimnoneill/paper-to-field-training huggingface dataset:
Mycelial Growth and Amylase Production by Talaromyces emersonii

Field: Agricultural and Biological Sciences (Life Sciences)

SUMMARYExtracellular amylase synthesis by Talaromyces emersonii was studied in stationary liquid starch-yeast-extract (SYE) medium. Maximum mycelium and extracellular amylase were produced at 40–45 C, but maximum amylase was produced after autolysis. There was some variation in the relationship between mycelial dry weight and amount of amylase synthesized at the other temperatures tested. Amylase activity was highest at 40–45 C and pH 5–6. Increasing the amount of starch in the medium enhanced mycelial growth and extracellular amylase production. Besides starch, amylase production was also induced when T. emersonii was grown in media containing cellobiose, glucose, fructose, galactose or maltose, but the amount of amylase produced on these carbohydrates was less than when the medium contained starch. Amylase was not produced when sucrose was used as a carbon source.
Co-creating Norwegian DigiPer: a digital tool including peer support for managing mental, physical, and social health in serious mental illness

Field: Health Professions (Health Sciences)

Abstract

Background People with serious mental illness (SMI) often encounter physical health issues, a lack of focus on self-management, and persistent symptoms of mental illness. Strategies to empower people with SMI to self-manage their mental, physical, and social health are needed. The PeerTECH application is an American digital peer support intervention that can help manage health issues and promote self-management skills for people with SMI. This study aims to co-create a Norwegian version of PeerTECH, DigiPer, with service users, peer support workers, and professionals from Norwegian community mental healthcare. Methods This study employs a qualitative design using principles of co-creation to develop the Norwegian DigiPer. We conducted workshops, videoconference demonstrations, and application testing with key stakeholders in the co-creation process. The data collected were analyzed using thematic analysis. Results Five themes and ten subthemes were developed in the data analysis. The first theme reflected feedback and challenges in DigiPer functioning, with the subthemes of Usability in DigiPer and Managing complexity in DigiPer classes. The second theme focused on the peer support worker's role, with subthemes of recognizing and addressing user challenges and balancing self-responsibility and support. The third theme focused on the content of DigiPer in addressing day-to-day challenges, with subthemes of supporting personal growth and goal setting and DigiPer as a tool to build supportive networks. The fourth theme highlighted the use of DigiPer to encourage a healthy lifestyle, with subthemes of addressing substance use and smoking habits and improving sleep and stress management. The fifth theme provided a holistic view of health, with subthemes of connecting users to relevant services and a need for support to overcome financial challenges. Conclusions DigiPer has good usability among community mental healthcare stakeholders and has proper functionality, which is relevant to the Norwegian context. Although challenges exist, all participants perceived DigiPer as a meaningful and promising tool to help people with SMI improve their self-management of their mental, physical, and social health. Future studies should assess the accessibility and feasibility of the Norwegian DigiPer.
Multiple melanoma and atypical melanocytic naevi—evidence of an activated and expanded melanocytic system

Field: Medicine (Health Sciences)

Twelve patients with malignant melanoma and/or multiple atypical naevi are described. Of these, three were familial and four were sporadic cases of a syndrome characterized by multiple irregular melanocytic naevi and multiple primary cutaneous malignant melanomata. The other five were cases of multiple atypical naevi without malignant melanoma. Three new features emerge from this study: (1) in these patients malignant melanoma may develop on clinically normal skin; (2) melanocyte counts in normal skin adjacent to the lesion show an expanded population of epidermal melanocytes; (3) most of these patients (9/12) give a history of significant sun exposure. The unsatisfactory terminology previously used in describing this syndrome is discussed, and the term expanded and activated melanocyte syndrome is offered as an alternative.
Co-Optimization Scheduling of Electricity and Natural Gas Systems Considering Railway Transportation

Field: Energy (Physical Sciences)

The electrified railway system with liquefied natural gas (LNG) transported is closely related to the integrated electricity-gas energy system, but little research focuses on the coordinated optimal operation of these systems. To fill the gap, this paper innovatively proposes the co-optimization scheduling model of electricity and natural gas systems considering railway transportation. Firstly, a railway network model for LNG transmission is put forward. Then a co-optimization scheduling model for the integrated electricity-natural gas system and railway system is established. Finally, the incremental linear approximation is adopted to transform the original model into a mixed integer linear programming model. The results of case studies show that the proposed co-optimization scheduling model is beneficial to reduce operating costs and promote the accommodation of renewable energy.
How Much Are Consumers Willing to Pay for a Greener Hotel Industry? A Systematic Literature Review

Field: Economics, Econometrics and Finance (Social Sciences)

This work uses the systematic literature review (SLR) method to explore the premium that consumers would be willing to pay to stay at a green hotel. To the best of the author’s knowledge, it is the first review on this topic and, thus, fills a gap in the existing literature. The search process identified 22 articles from 13 countries which were analyzed to explore three principal research questions regarding the valuation methods used to estimate the premium, the size of the premium, and the factors affecting the premium. From a policy perspective, the analysis shows that the lack of studies on the topic is a serious obstacle to the hotel sector’s efforts to reduce its environmental footprint. From a managerial perspective, it is argued that consumers who are willing to pay to stay at green hotels would accept a premium of around 5%. Finally, from an estimation perspective, the analysis highlights specific gaps in and limitations of current studies that should be considered in future research efforts relating to the geographical coverage, accommodation type, factors affecting the premium that hotel customers would pay for green initiatives, and certain methodological issues, among others.
Survival of transgenic glyphosate-and insect-resistant cotton in non-cultivated land

Field: Agricultural and Biological Sciences (Life Sciences)

[Background]Safety assessment of transgenic crop plants has been a concern, and only limited knowledge can be obtained from pre-release experiments. Once released, the survival and competitiveness of transgenic crops in non-cultivated land is one of the most important safety concerns. [Method]We tested three transgenic cotton cultivars, two double-construct transgenic glyphosate- and insect-resistant cotton cultivars, and one non-transgenic cotton (CCRI 49), which was the isogenic control. Seeds were scattered on the soil surface, or planted 3 cm deep in late April and late May. We compared the growth parameters among the examined cotton varieties monthly from April to September, including survival rate, plant height, leaf number, stem diameter, sympodial branch number, bud and boll numbers, in order to test and evaluate their competitiveness on non-cultivated land and the risk of weediness. [Result]Transgenic glyphosate- and insect-resistant cotton in wasteland was weak and stunted with slow and retarded growth. Only a few individuals sown in late April could produce a few small bolls; these were without mature seeds. Plants sown in late May were weaker, and no bud appeared until late September. [Conclusion and significance]Transgenic glyphosate- and insect-resistant cotton had no competitive advantage and limited reproductive capacity on non-cultivated land, and consequently, low weediness potential.
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Field: Medicine (Health Sciences)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Pengaruh Kepemimpinan Transformasional Dan Lingkungan Kerja Terhadap Kepuasan Kerja Pegawai

Field: Business, Management and Accounting (Social Sciences)

This study aims to determine and analyze the positive and significant influence of transformational leadership and the work environment on the job satisfaction of regional secretariat employees in Magelang City. The research method uses quantitative research with multiple regression analysis and data collection techniques carried out online through questionnaires. The results of the study revealed that transformational leadership had a significant effect on the job satisfaction of regional secretariat employees in the city of Magelang with a count of 2.300 > t table of 1.660. Second, the work environment has a significant effect on the job satisfaction of regional secretariat employees in Magelang City with a t count of 9.337 > t table of 1.660. Third, transformational leadership and the work environment significantly influence the job satisfaction of regional secretariat employees in Magelang City with an f count of 71.908 > f table of 3.09. The conclusion of this study is that there is a positive and significant effect of transformational leadership and the work environment on the job satisfaction of regional secretariat employees in Magelang City.
Developments of GaN-based VCSELs with epitaxially grown DBRs

Field: Materials Science (Physical Sciences)

We will show our two recent results related to GaN-based VCSELs with AlInN/GaN DBRs. One is in-situ wafer curvature control of AlInN/GaN DBRs. Curvature data successfully provides us the strain condition in the AlInN layers, which leads to a high reproducibility for fabricating the AlInN/GaN DBRs. The other is laser operation of the VCSELs with large current apertures. While our previous VCSELs with only 8-15 µm apertures showed RT CW operations, our recent VCSELs now show RT CW operations with 5-30 µm apertures. such larger apertures will eventually provide much higher LOPs in the future.
Association of several loci of SMAD7 with colorectal cancer: A meta-analysis based on case–control studies

Field: Medicine (Health Sciences)

Background: Sma-and mad-related protein 7 (SMAD7) can affect tumor progression by closing transforming growth factor-beta intracellular signaling channels. Despite the extensive research on the correlation between SMAD7 polymorphisms and colorectal cancer (CRC), the conclusions of studies are still contradictory. We conducted a study focusing on the association of SMAD7 polymorphisms rs4939827, rs4464148, and rs12953717 with CRC. Methods: We searched through 5 databases for articles and used odd ratios (ORs) and 95% confidence intervals (CIs) to discuss the correlation of SMAD7 polymorphisms with CRC risk. The heterogeneity will be appraised by subgroup analysis and meta-regression. Contour-enhanced funnel plot, Begg test and Egger test were utilized to estimate publication bias, and the sensitivity analysis illustrates the reliability of the outcomes. We performed False-positive report probability and trial sequential analysis methods to verify results. We also used public databases for bioinformatics analysis. Results: We conclusively included 34 studies totaling 173251 subjects in this study. The minor allele (C) of rs4939827 is a protective factor of CRC (dominant, OR/[95% CI] = 0.89/[0.83–0.97]; recessive, OR/[95% CI] = 0.89/[0.83–0.96]; homozygous, OR/[95% CI] = 0.84/[0.76–0.93]; heterozygous, OR/[95% CI] = 0.91/[0.85–0.97]; additive, OR/[95% CI] = 0.91/[0.87–0.96]). the T allele of rs12953717 (recessive, OR/[95% CI] = 1.22/[1.15–1.28]; homozygous, OR/[95% CI] = 1.25/[1.13–1.38]; additive, OR/[95% CI] = 1.11/[1.05–1.17]) and the C allele of rs4464148 (heterozygous, OR/[95% CI] = 1.13/[1.04–1.24]) can enhance the risk of CRC. Conclusion: Rs4939827 (T > C) can decrease the susceptibility to CRC. However, the rs4464148 (T > C) and rs12953717 (C > T) variants were connected with an enhanced risk of CRC.
Review: Mental health symptoms and their associated factors among pharmacists in psychiatric hospitals during the early stage of the COVID-19 pandemic — R2/PR13

Field: Health Professions (Health Sciences)

As frontline workers, pharmacists often face significant work stress, especially in psychiatric settings. A multicenter cross-sectional design was conducted in 41 psychiatric hospitals. The Depression, Anxiety and Stress Scale–21 (DASS-21) was used to measure the mental health of 636 pharmacists. We also collected demographic data and work-related variables. The prevalence of depression, anxiety and stress was 20.60%, 22.96% and 8.96%, respectively. Multivariate logistic regression showed that several common factors were associated with depression, anxiety and stress, including professional identity (odds ratio [OR] = 0.132, 0.381 and 0.352) and verbal violence (OR = 2.068, 2.615 and 2.490). Those who were satisfied with their job were less likely to develop depression (OR = 0.234) or anxiety (OR = 0.328). We found specific factors associated with mental health. Older age (OR = 1.038) and perceived negative impact (OR = 2.398) of COVID-19 on medical work were associated with anxiety, and those with frontline experience with COVID-19 patients (OR = 2.306) were more likely to experience stress. More than one-fifth of pharmacists in psychiatric hospitals experienced symptoms of depression or anxiety during the pandemic, highlighting the need for policy change to improve workplace conditions and psychological well-being for this professional group.
Simultaneous Contents Determination of Three Constituents in Compound Norfloxacin Ear-Drops by HPLC(Gradient Elution)

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective To establish a HPLC analysis method for contents determination of norfloxacin,metronidazole and beclomethasone propionate in compound norfloxacin ear-drops. Methods The kromasil C18 column(4.6 mm×250 mm,5 μm) was used,the methanol-acetonitrile-0.025 mol·L-1 phosphoric acid solution(adjusted to pH 3.0 with triethylamine)-water for injection was applied as mobile phase,and the sample was eluted in gradient. Results The linear ranges of norfloxacin,metronidazole and beclomethasone propionate were at 15.0～150.0 μg·mL-1(r=0.999 4),15.1～151.0 μg·mL-1(r=0.999 3)and 2.6 ～ 26.0 μg·mL-1(r=0.999 4),respectively,and the average recovery rate(n=9)were 99.5%,99.7% and 99.5% with RSD as 0.80%,0.78% and 0.92%,respectively. Conclusion The method is simple,rapid and sensitivity,which is suitable for the content determination of compound norfloxacin ear-drops.
Effects of carbohydrate sources on a biofloc culture system for white leg shrimp (Penaeus vannamei)

Field: Agricultural and Biological Sciences (Life Sciences)

The addition of carbohydrate stimulates biofloc growth and the latter improveswater quality and reduces the need for water exchange, while the flocculatedmaterials serve as natural shrimp feed. T his research aimed at comparing effectsof corn starch and molasses addition on the white leg shrimp (0.07 g/individual)stocked indoor at 250 individual/m3, with aeration and lighting, and fed with 37% protein and CIN ratio of 12. Both corn starch and molasses additions resulted in low Total Ammonia Nitrogen levels. The amount of bioflocs in both treatments increased over time. In the molasses treatment the periphyton growth was higher at the end of the experiment and had higher crude protein content compared to corn starch. But the latter resulted in significantly higher growth rate, production, average weight of the shrimp, and lower FCR. Nitrogen retention in the corn starch treatment was greater than that in the molasses treatment.
Imbalance of k/lambda ratios associated with high measles antibody titers in fractionated serum immunoglobulins of patients affected with subacute sclerosing panencephalitis.

Field: Medicine (Health Sciences)

Subacute sclerosing panencephalitis (SSPE) is a neurological disease which is characterized not only by the appearance of oligoclonal immunoglobulins in cerebrospinal fluid (CSF) and serum but also by high measles antibody titers and disturbed k/lambda ratios, as well in serum as in CSF. These findings lead to the hypothesis that specific immunoglobulins are produced by hyperimmunisation against measles and/or measles-like virus. Therefore the serum IgG from subacute sclerosing panencephalitis patients were fractionated by column isoelectric focusing and the k/lambda light chain ratio and the measles antibody titer of each fration were determined. The highest k/lambda ratios and the highest measles antibody titers were found mainly in two fractions at a pH ranging from 8.94-8.51 for the first and 8.88-8.24 for the second.
On the feasibility of distributed systems for interactive visual analysis of omics data

Field: Computer Science (Physical Sciences)

The purpose of this thesis is to discuss the feasibility of developing a distributed interactive visual analysis omics system demonstrating how selected modules from the standalone J-Express Modularized application can be converted into a web based distributed system maintaining the original application's interactivity and functionality. A distributed system is considered as the main architectural design, where the client-side will mainly be responsible for managing the interactive visualisation of the generated results, and the server-side is responsible for the remote processing and storage of the data files in addition to sharing the data resources between the users. A prototype system of an interactive visual data analysis of omics data will be implemented as an online service to non-technical life science researchers. This provides the opportunity to address the main challenges and limitations of such systems, as well as outlining the additive benefits to the omics-data analysis process achieved by the use of distributed systems. The main goal for this thesis can thus be summarised as: Investigate the feasibility of developing a web distributed system that supports interactive visualisation of omics data analysis based on converting selected modules from J-Express Modularized, and discuss the main benefits and limitations of such a system. From the study and the prototype evaluation, we conclude that even with the current limitations for the browser memory and computing capabilities, it is still feasible to develop a browser based distributed system for interactive visual analysis of omics data. This system will achieve good performance, scalability, besides being biologist- friendly.
The study of the role of Mao Zedong in Chinese entry to the Korean War

Field: Social Sciences (Social Sciences)

General Douglas MacArthur and President Harry Truman were convinced that the Chinese would not have intervened in the Korean War. This was further supported by China who had expressed that it would not interfere in Korea’s internal affairs. However, in October 1950, Chinese troops began to cross the Yalu River and engaged in a series of large-scale attacks against the forces of the United Nations. This results in a change in the nature of the war. Hence, by focusing on the period from 1940-1953, this paper would first aimed to highlight the missed opportunities that could have prevented China from entering the war. Following that, by analyzing the various factors that had caused China to enter the Korean War, this paper would argue that Mao Zedong was using China’s involvement in the Korean War as a political tool in gaining affirmation for his leadership in China. Last but not least, this paper would look into how Mao Zedong used propaganda in getting support for his decision.
Chip platforms with synthetic lipid bilayers for electrophysiological analyses of pore proteins and extracellular vesicles

Field: Engineering (Physical Sciences)

Abstract In this paper, we present microfluidic chip platforms to enable electrophysiological measurements of nanometer-sized extracellular vesicles. The basis of the chip platform is the realization of a synthetic free-standing lipid bilayer spanned within a microfabricated aperture. To allow ion channel current measurements, the background current noise level should be reduced to a minimum. This can be realized by coating microfabricated apertures from silicon, silicon oxide, or silicon nitride with PTFE or Parylene. Three promising chip platform designs are presented. Electrophysiological measurements conducted with these microfluidic systems show gating events of membrane proteins fused into synthetic lipid bilayers.