jimnoneill/paper-to-field-training huggingface dataset:
HVAC visualization toolkit

Field: Engineering (Physical Sciences)

Nowadays, the idea of automation control and monitoring is applied to all kind of industrial systems, plants and building management. The aim of the automation and monitoring technology is to reduce energy cost, save maintenance cost and collect more information for user to make operation decisions. This project, HVAC Visualization Toolkit, is to develop a generic HVAC visualization component toolkit, based on the principles behind visual analytics, for dynamically exploring time-varying, geographically referenced and multivariate attributes simultaneously. It provides the features to help operator view real time status of building’s HVAC condition on Temperature, Humidity, Air Flow and other relevant properties. Operator is able to remotely monitor and control the HVAC Units, to achieve the main goal of saving energy and cost. For this project, OPC Communication is the communication protocol between the HVAC units and HVAC Visualization Toolkit. Basic concept of OPC communication protocol is mentioned in the follow main body of the report. Software Matrikon OPC Server is used to establish the communication between HVAC units and HVAC Visualization Toolkit. The OPC server is performing as a bridge, communicates to the both sides. It creates the OPC software tags for both sides systems to access, read and write. Software Siemens WinCC is the project development environment. Siemens WinCC is a reliable industrial interface development software, which is widely used in all kind of industrial, like Marine ship building, Oil and Gas Safety Monitoring and Control. One of reasons of choosing WinCC is because the author is a Siemens Certificated Process Control System engineer; while he has 4 years project experience of using Siemens Simatic Family software. Last, the System is tested during the final period of project development, tested with dummy tags and simulated with real situation.
A Results Oriented Maintenance Approach for Nuclear Emergency Diesel Generators

Field: Engineering (Physical Sciences)

<div class="htmlview paragraph">Recent emphasis on increasing the availability of nuclear emergency diesel generators (EDG's) has motivated the industry to re-evaluate the maintenance philosophies utilized for these units. Improving availability, while maintaining or enhancing the existing levels of reliability, has become the challenge to nuclear utilities. In order to meet quantified reliability and availability objectives, a renewed approach to maintenance is required. The direction taken includes the initiation of a diagnostic data monitoring and trending program to assess those parameters where such methods have proven to be effective. In addition, prescribed inspections based on historical findings are recommended where needed. Periodic reviews are proposed to provide further program improvement.</div>
インドネシアSemeru火山の火山性地震・微動

Field: Earth and Planetary Sciences (Physical Sciences)

Semeru volcano, an andesitic stratovolcano in East Java, Indonesia has erupted inter-mittently for more than 50 years. On February 3, 1994, the volcano erupted violently accompanied with remarkable pyroclastic flows. Seismic activity prior to the eruption was characterized by occurrence of deep volcanic earthquakes, and successive increase in shallow earthquakes and tremors continuing for 9 days until the eruption. Such a sequence of the seismic activity has been often observed at Sakurajima. Volcanic earthquakes and tremors observed at the volcano are quite similar to those recorded at Sakurajima and Suwanosejima volcanoes; those are A-type earthquakes, B-type earthquakes, explosion-earthquakes, harmonic (C-type) tremors and non-harmonic tremors. Spectral analysis for these events at the three volcanoes were done. The peak frequencies of them at Semeru and Sakurajima are almost same, but lower than those at Suwanosejima. This result suggests that Semeru has a shallow magma conduit of similar size with that of Sakurajima. It is noteworthy that harmonic tremors at Semeru have a few discrete frequency peaks of integer multiple, and the frequencies change with time, similar to those at the other two volcanoes.
Effectiveness of non-auditory verbal therapies in improving speech production in school-aged hearing-impaired children: A critically appraised topic

Field: Health Professions (Health Sciences)

A critically appraised topic (CAT) is one form of rapid review that can be particularly useful for informing practice (White, Raghavendra, & McAllister, 2017). The purpose of this CAT was to determine the effectiveness of non-auditory verbal therapies in improving speech production in school-aged children who are hearing impaired. In addition to the methodology, the authors present and discuss the findings of this CAT. The authors propose an update to this CAT in January 2020.
Conversion of conjugatedcis‐trans octadecadienoates to thetrans‐trans isomers1,2,3

Field: Chemistry (Physical Sciences)

Summary The conversion of methyl conjugated cis‐trans octadecadienoate to the trans‐trans isomer takes place easily in the presence of iodine and light. The reaction is more rapid in carbon disulfide than in Skellysolve C, and it is quite slow and accompanied by loss of conjugation in methanol. The rate of conversion increases with iodine concentration and light intensity and decreases with increasing fat concentration. It is affected by temperature also, but to a lesser degree. the influence of light may result from its catalytic effect on the decomposition of a reversible fat‐iodine complex. The reaction appears to be pseudo‐first order with respect to the substrate but is complicated by side reactions which inactivate the catalyst and destroy conjugation. The reaction occurs, at a measurable rate, with iodine in the dark, or in light without iodine, but no conversion takes place without iodine in darkness. The isomerization reaches an equilibrium when approximately 71% of the conjugation present is in the trans‐trans form. This equilibrium can be attained by starting with either cis‐trans or trans‐trans material. Very little, if any, cis‐cis isomer is present in the equilibrium mixture.
Unique Skin Metastasis from Recurrent Cancer. Case Report

Field: Medicine (Health Sciences)

Iordanis Papadopoulos Department of Aesthetics and Cosmetology, Alexander Technological Educational Foundation, Thessaloniki, GreeceCorrespondence: Iordanis Papadopoulos Email driordanis@yahoo.grIntroduction: Cutaneous metastasis is defined as the dissemination of malignant cells from a primary tumor to the skin. Skin may be affected by tumors, either through direct invasion from an adjacent organ or by cutaneous metastasis from an internal organ malignancy. We report a case of a 75-year-old female patient with skin metastasis 8 years after the initial treatment of primary breast cancer.Patient Concern: The patient presented only with papules and nodular skin lesions in the left lateral abdominal area, without any other clinical manifestations.Diagnosis: All laboratory tests were normal. Histological examinati revealed the infiltration of the dermis by tumor cells.Interventions/Outcome: After the diagnosis of skin metastasis, she was treated with chemotherapy with complete remission of skin lesions.Conclusion: Skin metastasis from internal organs is rarely the first sign. In this case, skin metastasis was the only clinical sign and the only diagnostic tool to drive to the correct diagnosis of a recurrent cancer after 8 years. Dermatologists might be the first doctors to facilitate the diagnosis of skin metastasis.Keywords: skin metastases, breast cancer, neoplasm metastases
Local Structure Analysis of Li-substituted (Bi<sub>0.5</sub>Na<sub>0.5</sub>)TiO<sub>3</sub> and NaNbO<sub>3</sub>

Field: Materials Science (Physical Sciences)

(Bi0.5Na0.5)TiO3 and NaNbO3 are ABO3 perovskite ferroelectric materials and they are considered to be promising lead-free ferroelectric materials because of their relatively high piezoelectric properties in lead-free piezoelectric ceramics. Furthermore, disordered rhombohedral phases are included in their phase transition sequences. In these disordered phases it is possible by substituting Na for Li to induce ordered ferroelectric phases. The purpose of this work was to clarify the local structures of Li-substituted (Bi0.5Na0.5)TiO3 and NaNbO3 to elucidate the mechanism of the stabilization of the ordered ferroelectric phases. A local structure analysis was carried out using the X-ray absorption fine structure (XAFS) the X-ray pair-distribution function (PDF) obtained from high-energy synchrotron X-ray diffraction. Although XAFS and PDF are the local structure analysis techniques, the Li substitution effect was observed clearly in PDF, but not observed in XAFS. The difference in the coherence of the local structure analysis in XAFS and PDF indicates that the ordered structure of (Bi0.5Na0.5)TiO3 and NaNbO3 is stabilized by excluded volume effect.
Full Article A Survey on the Gastrointestinal Parasites of Rabbit and Guinea Pig in a Laboratory Animal House

Field: Veterinary (Health Sciences)

There is docum ented evidence that infection in laboratory animals can often influence the outcome of experiments. All infections, apparent or inapparent, are likely to increase biological variability. As a research project concerning the diversity and distribution of parasites of rabbit and guinea pig in a conventional laboratory animal house, about 87 rabbits (from 700 ) and 105 guinea pigs (from 1500 ) were selected randomly from a Research, Production & Breeding of Laboratory Animals Department. Samples were collected between 19.02.2010 and 20.05.2011. The samples and animals were examined by dissection and flotation methods. In this study only one species of nematodes (Passalorus ambiguus: 6.9%); one species of protozoa (Eimeria spp.: 21.8%) in rabbits and one species of nematodes (Paraspidodera Uncinata: 24.7%); one species of protozoa (Balantidium coli: 11.4%) in guinea pigs were identified. However, there was not any cestodes or trematodes identified from this group of laboratory animals.
Improving Customer Engagement of Food and Beverage Small and Medium Enterprises (MSMEs) Through E-Commerce and Content Marketing Training

Field: Business, Management and Accounting (Social Sciences)

Over the past five years, the rapid growth of MSMEs in Indonesia has also resulted in many MSMEs going bankrupt. However, this rapid growth of MSMEs is also accompanied by many MSMEs going bankrupt due to mismanagement and low competitiveness caused by the lack of adaptability to business digitalization through e-commerce and product promotion strategies through digital media. Similar problems are also experienced by Food and Beverage MSMEs in Ketintang Village, Surabaya. This drives the importance of increasing competitiveness with more effective business management and digital marketing strategies through community service programs in this area. This community service-based research consists of online store design training activities in e-commerce marketplaces and content marketing with outputs in the form of scientific publications in indexed international journals, publications in the mass media, increasing community understanding and skills, and YouTube videos aimed at improving customer engagement in e-commerce marketplaces. Using the experimental method, this study concluded that SMEs showed a positive perception of the importance of e-commerce in increasing market reach and sales and insight into digital marketing in compiling content marketing that can increase customer engagement for food and beverage products.
The effect of high mobility group box 1 with interleukin-1β or lipopolysaccharide on the proliferation and inflammatory phenotype of synoviocytes in rheumatoid arthritis

Field: Medicine (Health Sciences)

Objective
To investigate the effect of high mobility group box chromosomal protein 1 (HMGB-1) on the proliferation and inflammatory phenotype of human fibroblast like synoviocytes (FLS).

Methods
FLSs were isolated from the synovial tissues of rheumatoid arthritis (RA) patients undergoing joint replacement surgery. All the experiments described here utilize the FLSs between the third and sixth passages. FLS were incubated with HMGB1 at (100, 500, 2 000 ng/ml) or interleukin (IL)-1β (0.5 ng/ml) or lipopolysaccharide (LPS) (100 ng/ml) alone or HMGBl/IL-1β complexes or HMGB1/LPS complexes. Cell proliferation assay were used by CCK-8, IL-6, IL-8 and matrix metalloproteinase-3 (MMP-3) in culture supernatants were measured using enzyme-linked immunosorbent assays. The measurement data were compared with single factor analysis of variance.

Results
Stimulation with all concentrations of HMGB1, IL-1β and LPS alone did not affect the cell proliferation of FLS. HMGBl/IL-1β complexes and HMGB1/LPS complexes did not affect the cell proliferation of FLS, neither (F=0.415, P=0.915). Except high concentration of HMGB1 (2 000 ng/ml) could significantly stimulate the secretion of IL-6 from FLS [(23.0±1.1) ng/ml], HMGB1, IL-1β and LPS alone did not affect the production of IL-6, IL-8 and MMP-3. However, HMGBl/IL-1β complexes and HMGB1/LPS complexes increased IL-6, IL-8 and MMP-3 production from FLS (F=97.804, 117.383, 70.179, P =0.000).

Conclusion
Neither HMGB1, IL-1β, LPS alone nor HMGBl/IL-1β complexes or HMGB1/LPS complexes affect the cell proliferation of FLS. HMGB1 in complex with LPS or IL-1β boost IL-6, IL-8 and MMP-3 production in synovial fibroblasts from RA patients.

Key words:
Arthritis, rheumatoid; Fibroblast-like synoviocytes; High mobility group box 1 protein; Matrix metalloproteinase; Inflammatory cytokines
Inequalities for means of chords, with application to isoperimetric problems

Field: Mathematics (Physical Sciences)

We consider a pair of isoperimetric problems arising in physics. The first concerns a Schrödinger operator in L 2 (R 2) with an attractive interaction supported on a closed curve Γ, formally given by − ∆ − αδ(x−Γ); we ask which curve of a given length maximizes the ground state energy. In the second problem we have a loop-shaped thread Γ in R 3, homogeneously charged but not conducting, and we ask about the (renormalized) potential-energy minimizer. Both problems reduce to purely geometric questions about inequalities for mean values of chords of Γ. We prove an isoperimetric theorem for p-means of chords of curves when p ≤ 2, which implies in particular that the global extrema for the physical problems are always attained when Γ is a circle. The article finishes with a discussion of the p–means of chords when p&gt; 2. 1
Inflammatory and Bleeding Risks on Clinical Outcomes in Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention

Field: Medicine (Health Sciences)

Abstract This study aimed to evaluate the impact of systemic inflammation burden using high-sensitivity C-reactive protein (hsCRP) and long-term prognosis in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) stratified by bleeding risk status. Consecutive patients admitted for ACS and who received PCI between March 2016 and March 2022 were enrolled in the analysis. Elevated systemic inflammation was defined as hsCRP >2 mg/L, and high bleeding risk (HBR) was defined the Academic Research Consortium (ARC)-HBR criteria. The primary outcome was ischemic events at 12 months, composed of cardiac death, myocardial infarction, and/or stroke. The main secondary outcomes included all-cause death, and Bleeding Academic Research Consortium (BARC) types 2, 3, and 5 bleeding and types 3 and 5 bleeding. Of 15,013 patients, 4,606 (30.7%) were qualified as HBR and 8,395 (55.9%) had hsCRP >2 mg/L. Elevated hsCRP was consistently associated with higher risk of ischemic events in both HBR (adjusted hazard ratio [aHR]: 1.20; 95% confidence interval [CI]: 0.91–1.58) and non-HBR (aHR: 1.34; 95% CI: 1.01–1.78) subgroups (P interaction = 0.755). Although the incidence of bleeding events was higher in HBR patients, an elevated hsCRP level was not associated with bleeding events regardless of HBR status. Restricted cubic spline regression represented an inverse J-shaped relation between hsCRP and non-HBR for ischemic events (P nonlinearity <0.001) and all-cause death (P nonlinearity = 0.003). Regardless of HBR status, high levels of hsCRP were associated with an increased risk of ischemic events and all-cause death in ACS patients following PCI, but not for bleeding.
Sound generation and upstream influence due to instability waves interacting with non-uniform mean flows

Field: Physics and Astronomy (Physical Sciences)

Recent experiments reveal that mean spreading rates of artificially excited shear layers undergo abrupt changes at certain discrete positions within the flow. This paper is concerned with the interaction between externally excited instability waves and these regions of relatively sudden change in mean flow. While the main emphasis is on the acoustic field produced by these interactions, the upstream influence at the nozzle lip is also considered.
Murine WNT11 is a secreted glycoprotein that morphologically transforms mammary epithelial cells.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Wnt genes encode a set of structurally related cell surface glycoproteins that appear to have roles in cell-cell signalling. The ectopic expression of several murine Wnt genes has been implicated in the transformation of mammary epithelial and the onset of mammary tumours. Wnt11 is expressed in the developing embryo in a variety of structures including the dermatome/myotome junction of the somites, the truncus ateriosus region of the heart and limb mesenchyme. Here we report that Wnt11 encodes a glycoprotein that is secreted from expressing cells and becomes associated with the extracellular matrix. In addition, Rat2 fibroblasts expressing WNT11 (which are not morphologically altered themselves) are able to induce the transformation of adjacent C57MG mammary epithelial cells in co-culture experiments. These results suggest that WNT11 functions via a paracrine signalling mechanism to have a direct effect on the morphology and growth characteristics of mammary epithelial cells.
Cardiac Rehabilitation in Peripheral Artery Disease in a Tertiary Center—Impact on Arterial Stiffness and Functional Status after 6 Months

Field: Medicine (Health Sciences)

Background and Objectives: Cardiac rehabilitation (CR) plays an essential role in peripheral artery disease (PAD), leading to improved functional status, increased quality of life, and reduced arterial stiffness. We aimed to assess factors associated with clinical improvement 6 months after enrolment in a rehabilitation program at an academic medical center in north-eastern Europe. Materials and Methods: We conducted a prospective cohort study on 97 patients with PAD admitted to a single tertiary referral center. At the 6-months follow-up, 75 patients (77.3%) showed improved clinical status. We analyzed demographics and clinical and paraclinical parameters in order to explore factors associated with a favorable outcome. Results: Hypertension (p = 0.002), diabetes mellitus (p = 0.002), dyslipidemia (p = 0.045), and obesity (p = 0.564) were associated with no clinical improvement. Smoking cessation (p < 0.001), changing sedentary lifestyle (p = 0.032), and improvement of lipid and carbohydrate profile as well as functional status parameters and ambulatory arterial stiffness index (p = 0.008) were factors associated with clinical improvement at the 6-months follow-up. Conclusions: PAD patients require an integrative, multidisciplinary management to maintain functional status and increase quality of life. Improving carbohydrate and lipid profile, adopting a healthy lifestyle, quitting smoking and increasing exercise capacity are predictors for clinical improvement 6 months after enrolment in a CR program.
Distal femoral osteotomy for multidirectional malunion using 3D printing technology: a case-report

Field: Medicine (Health Sciences)

Multidirectional distal femoral malunion and limb shortening lead to functional deficit and decreased quality of life. A corrective osteotomy might be necessary to cope with these issues. The inception of computer-assisted planification and the introduction of patient-specific instrumentation based on 3D printing technology with personalized osteotomy guides provide high correction accuracy, effectiveness, time-saving, and reduce potential complications. The present study describes a case of correction osteotomy using this procedure in a young patient with multidirectional malunion who recovered from a painful joint with functional limitations at a two-year follow-up.
HPV infection and its correlation with human telomerase reverse transcriptase and survivin expression in vulvar squamous cell carcinoma

Field: Medicine (Health Sciences)

Objective: To investigate HPV infection and its correlation of the expression of human telomerase reverse transcriptase (hTERT) and survivin in vulvar squamous cell carcinoma (VSCC). Methods: HPV DNA 6/11 and 16/18 were detected by PCR in 31 cases of VSCC and 13 specimens of normal skin. The expression of hTERT mRNA was measured by in situ hybridization technique and survivin was assayed by immunohistochemical method. Results: The infection rates of HPV6/11 and 16/18 in VSCC were 25.81% and 38.17% respectively, and no HPV6/11 or HPV16/18 DNA was discovered in normal skin epidermis. The expression percentages of hTERT and survivin in VSCC were higher than those in normal skin respectively. The expression of hTERT was positively correlated with that of survivin in VSCC. hTERT expression in HPV16/18 positive lesion was higher than that in HPV16/18 negative lesion, and expression of survivin in HPV16/18 positive lesion lower than that in HPV16/18 negative lesion. Conclusions: HPV infection, the expression of hTERT and survivin might play important roles in the development of VSCC. The expression of survivin and hTERT in VSCC is interrelated.
EXPERIMENTAL INVESTIGATION OF SHIP HULL ULTIMATE-STRENGTH USING LARGE SCALE MODELS.

Field: Engineering (Physical Sciences)

This report summarizes the results of an experimental study to determine the ultimate strength of ship hull box girders. Two models were tested; the first model was designed and constructed to represent a typical single bottom tanker under bending condition. The second model was designed in an attempt to produce different modes of failure, such as plate buckling between stiffeners, instability of longitudinal stiffeners and overall grillage instability. Analytical formulae and experimental data analysis for determining the ultimate strength are introduced, and a comparison of the theoretical and experimental results of the two tests is presented.
Ithaka 2006 Survey of US Academic Librarian Attitudes and Behaviors

Field: Social Sciences (Social Sciences)

This study is designed to contribute to community understanding of the attitudes and behaviors of United States college and university librarians. This 2006 study builds upon studies that targeted United States faculty members in 2000 and 2003, and complements a similar study of United States faculty members that was conducted in 2006. Topics covered by this study include: the role of the library on the modern campus, impressions about electronic resources, digital institutional repositories, and the preservation of scholarly journals. This study was meant to develop a descriptive overview of librarians' attitudes, behaviors, perceptions, and priorities. It targeted collection development librarians at United States institutes of higher education, as well as some executive-level librarians at larger campuses (included to ensure an accurate reflection of high-level thinking in these types of schools). Respondents were asked questions such as "Which of the following best describes how your repositories are maintained or managed?" and "How important is working with faculty to incorporate information resources into their lectures and curricula?" Demographic information about institutional size was also gathered in this study. An overview of major findings may be found on the Ithaka Web site.