jimnoneill/paper-to-field-training huggingface dataset:
Pollutant emissions from Euro 6 light duty vehicle tested under steady state and transient operation on a roller test bench with hydrogenated paraffinic and biodiesel fuels

Field: Environmental Science (Physical Sciences)

[EN] The effort to implement more environmental-friendly fuels has been enhanced not only by the desire to reduce the greenhouse effects but also for public health issues. This paper studies the effects on pollutant emissions from a light-duty Euro 6 vehicle with four types of fuel: diesel (fossil origin, used as reference), biodiesel (renewable origin), Gas-to-Liquid (fossil origin) and farnesane (renewable origin). Both stationary engine and real-world driving cycles are studied. First, each fuel was tested in stationary modes in a vehicle test-bench and then tested in a realistic driving cycle with the same vehicle. This allows the separation the transient effects of the driving cycle from stationary results. Stationary tests lead to engine emission maps and driving cycle tests allow weighting the importance of each stationary condition during a realistic route. Instantaneous and cumulative CO, THC (total hydrocarbon), NOx and PN (particle number) emissions on route were obtained. The fuel that presented a highest level of emissions at stationary conditions was, for CO, diesel, for THC, diesel, for NOx, biodiesel and for PN, diesel. The behaviour of fuels during the driving cycles, from less pollutant to more pollutant, was: for CO, diesel, farnesane, GTL and biodiesel; for THC, GTL, farnesane, biodiesel, diesel. For NOx, farnesane and diesel (very similar values), GTL and biodiesel; for PN, GTL, biodiesel, farnesane and diesel.
Effect of Blood Plasma from Psychotic Patients upon Performance of Trained Rats

Field: Neuroscience (Life Sciences)

A variety of biochemical abnormalities has been described in schizophrenia. These include changes in glucose metabolism,1in adrenocortical physiology,2and in blood histamine,3ketones,4and glutathione.5Abnormal urine metabolites have also been described.6-8Weichbrodt9reported that the blood plasma from psychotic patients was toxic for mice, and Fischer10found it to be toxic to the larvae of Xenopus laevis. The latter conclusion has been disputed.11Shapiro12reviewed the literature on attempts to find a toxic substance in cerebrospinal fluid of schizophrenic patients; he was unable to detect such a factor when cerebrospinal fluid was injected subcutaneousely into rats. Leach and co-workers13found that the plasma in schizophrenia and certain other diseases oxidize epinephrine more rapidly than normal, and they have obtained a factor from the plasma of schizophrenics which is said to be qualitatively different from normal ceruloplasmin.14
EmHM: A Novel Hybrid Model for the Emotion Recognition based on EEG Signals

Field: Computer Science (Physical Sciences)

Emotion is a fundamental aspect of daily life and is crucial for human interactions. This study suggests a unique electroencephalogram (EEG)-based technique for identifying human emotions. For EEG-based emotion analysis, the proposed model is tested on the SEED and DEAP datasets. For the DEAP dataset, we consider valence and arousal emotions for classification purposes, and for the SEED dataset, three emotions, neutral, positive, and negative, have been considered. The differential entropy (DE) is used for the SEED dataset, and for the DEAP dataset, the power spectral density (PSD) is used as a feature. For precise emotion recognition, an EmHM (Emotion Hybrid Model) based on long short-term memory (LSTM) and a convolutional neural network (CNN) are constructed. Furthermore, we applied the CNN, LSTM, and EmHM models, and all three models for emotion recognition are fed with the retrieved information. Various methods improved on already-existing models to accurately classify human emotion. To get better accuracy than the existing techniques, we suggested a model that uses a different approach known as EmHM. By applying all three models such as CNN, LSTM and EmHM, we got the highest accuracy 86.50%, 87.98% and 91.56% respectively on dataset. To improve prediction results, the CNN and the LSTM models are combined to make the EmHM hybrid model.
COL11A1 is Downregulated by miR-339-5p and Promotes Colon Carcinoma Progression

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The roles of COL11A1 in cancer have been increasingly considered, but the understandings of the effects of COL11A1 on colon carcinoma progress are much limited yet. qRT-PCR and Western blot were utilized to evaluate COL11A1 expression at mRNA and protein levels, respectively, in colon carcinoma cell lines. Afterward, the tumorigenesis biological effects of COL11A1 were examined by CCK-8, colony formation, Transwell, and wound healing methods. Moreover, upstream miRNAs containing the binding sites with COL11A1 were predicted by the bioinformatics methods. The interplay between COL11A1 and miR-339-5p was identified by a dual-luciferase assay. COL11A1 expression was prominently upregulated in colon carcinoma cell lines relative to that in normal human colon mucosal epithelial cell lines, and it was related to tumor stages. The outcomes of in-vitro experiments suggested that interfering with COL11A1 remarkably repressed the malignant behaviors of SW480 and SW620 cells. MiR-339-5p was markedly lowly expressed in colon carcinoma cell lines. Furthermore, miR-339-5p directly targeted and negatively regulated COL11A1 expression. COL11A1 upregulation promoted colon carcinoma cell functions, while overexpressing miR-339-5p evidently attenuated the promotion. These results proved the modulation of the miR-339-5p/COL11A1 axis in colon carcinoma cells, and miR-339-5p repressed colon carcinoma progression via COL11A1 downregulation. These results offer new underlying targets for the accurate therapy of colon carcinoma patients.
Metastatic renal cell carcinoma (mRCC) in elderly patients: Can a personalized approach be an effective therapeutic option?

Field: Medicine (Health Sciences)

468 Background: Renal cell carcinoma (RCC) is the third most common genitourinary cancer. Up to 30% of patients (pts) with RCC presents with advanced disease. Sunitinib(S), an orally available tyrosine kinase inhibitor, is the well established first-line therapy for these population. Actually few data are available in the literature about its use in patients > 75 yrs investigating the feasibility, the efficacy and the toxicity in this population. Methods: From 2007 to 2011, 16 pts >75 yrs with mRCC received S. 75% of pts had a clear cell carcinoma, 87.5% had a surgery on primary tumor, 18.7% had a metastic disease at diagnosis and the median time to metastatic progression was 13.5 months. Median age was 78 years (range 71-88y).All patients had 0-1 performance status and 69% of them received S as first-line treatment. Four pts started S on the approved 50 mg /d 4-week-on-2-off schedule, but three of them reduced to 37.5 mg continuous once daily dosing(ODD)starting from the third cycle. Five out of 8 pts receiving 37.5 mg continuous ODD reduced the dose at 25 mg continuous ODD or modified the schedule. Four pts started with 25 mg continuous ODD and 2 of them continued the treatment at modified schedule. Median number of cycles administered was 7 (range 2-16). Results: Response rate was 87% (13pts) in 15 evaluable pts. Overall response included 40% (6 pts) of PR, 20% (3pts) of CR, 33% (5pts) of SD > 6 mos. Progressive disease was observed only in 1patient. TTP was 12.4 months (95% CI, 4.8-32.6). Overall survival was 34.2 months (95% CI, 27.3- ). The main toxicity requiring dose reduction or schedule modification was haematological (46%), G3Anemia in 1 pt G3-4 thrombocytopenia in 3pts and G3 leukoneutrophenia in 3pts. No any toxicity required treatment interruption. Conclusions: In summary these results show the feasibility and the efficacy of S in elderly population with high response rate regardless the doses and schedule used.
A Case of Fat Embolism Syndrome after Fracture of Tibia Fibula

Field: Medicine (Health Sciences)

Fat embolism syndrome is a fatal condition that affects several organs. It often occurs after trauma or orthopedic surgeries. Most are unnoticed, and treatment of it is primarily supportive, with early fracture repair as a preventative measure. This case report describes a patient who had a left tibia fibula fracture diagnosed using Gurd's criteria and verified by a CT pulmonary angiography and MRI, and was treated with supportive care. Bangladesh Crit Care J September 2024; 12 (2): 167-171
The Implications of Priming the "Latin Lover" Stereotype on Perceptions of Romantic Intentions: A Self-Categorization Theory Approach

Field: Psychology (Social Sciences)

Media effects research has yet to shed light on the effects of exposure to the stereotype of Latinos as passionate and seductive (i.e., Latin lovers). Research on priming ethnic group stereotypes indicates that the activated stereotype affects subsequent evaluations of members of the ethnic group. This study looked at the effects of priming the Latin lover stereotype on participants' judgments of unrelated targets. A self-categorization theory approach was invoked to account for individual differences in priming effects, by assessing the role that ethnicity salience and stereotype endorsement play in priming effects. The experiment found little support for the effects of priming the Latin lover stereotype. Ethnicity accessibility and stereotype endorsement mainly moderated priming effects dealing with perceptions of an unrelated White male target's romanticism, perceptions of an unrelated Latino male target's relational commitment, perceptions of a relationally-committed female target's ethnicity, and compatibility ratings involving the relationally-committed female target. Reasons for the weak priming results are discussed.
Globalization and Entrepreneurial Response in Post-Socialist Transformation: A Case Study from Transcarpathia, Ukraine

Field: Social Sciences (Social Sciences)

This paper sets out to examine the extent and characteristics of the globalization process in a region undergoing a process of socio-economic transformation. In doing so it draws upon the experience of an entrepreneurial, globally orientated, garment-making enterprise in Transcarpathia, the western most region of the Ukraine. The bulk of earlier scholarly research focused upon the consequences of the strategies implemented by multinational corporations. We argue, that this study points towards an alternative mode of integration in the global economy-one which received little attention in the Central and Eastern European context. This takes the form of a set of sub-contracting relationships between parent enterprises in Western Europe, intermediaries located in economies which achieved significant advances in the process of transformation (such as Hungary and Slovakia), and manufacturers in the locality.
Moore’s Paradox and Sorensen’s Iterated Cases

Field: Arts and Humanities (Social Sciences)

Abstract Chapter 14 argues that Sorensen’s iterated cases ‘p and I don’t believe that I believe that p’ and ‘p and I believe that I believe that not-p’ do not display Moore-paradoxical absurdity. Moreover, the chapter argues Sorensen is wrong that Moore-paradoxical absurdity decreases further with subsequent iterations, as in ‘p and I don’t believe that I believe that I believe that p’ and so on.
Presence of Conjugated Catecholamines in Rat Brain: A New Method of Analysis of Catecholamine Sulfates

Field: Neuroscience (Life Sciences)

Abstract: A new method of measuring catecholamine (CA) sulfate permitted us to detect its presence in rat brain for the first time. The procedure consisted of separating the CA sulfate from the free CA by alumina adsorption followed by passage through Dowex, and measuring the CA sulfate by a radioenzymatic assay in the presence of a sulfatase. This method permitted demonstration of the presence of dopamine sulfate, and occasionally, of norepinephrine and epinephrine sulfate in the hypothalamus, striatum, and hippocampus of rat brain.
[Prospects of using fluorescein angiography with oral administration of fluorescein in children].

Field: Neuroscience (Life Sciences)

Cortical topography of steady-state flash visual evoked potentials (fVEP) was compared with topography of transient fVEP and pattern VEP (pVEP) in 17 normal subjects. It was found that at low (up to 20 Hz) frequencies fVEP demonstrate extensive dissemination on the scalp. At higher frequencies (30 Hz or higher) fVEP were registered mostly in the occipital area similarly as transient pVEP. These results suggest that the neural structures responsible for the generation of transient pVEP and steady-state fVEP of 30 Hz and higher frequencies are anatomically identical.
Innovation management in the construction industry based on an ontological model

Field: Business, Management and Accounting (Social Sciences)

Aim. The presented study develops an ontological model of innovation from the industrial perspective (through the example of the construction industry) reflecting the relationship between innovation and the goals of their implementation and management objects, which would ensure the optimization of the innovation management system in the long term and facilitate the introduction of a quality assessment and selection system for more efficient operation of organizations. Tasks. The authors analyze the existing terminology and types of innovations at construction enterprises; classify the objects of innovation management; develop an ontological model of innovation at construction enterprises in the form of a directed graph. Methods. This study is based on the theory of innovation management, elements of system analysis, practical foundations of the organizational life cycle, and graph theory. Results. The obtained results can be used both in building an innovation management model at construction enterprises and in applying the methodology for assessing the quality of innovation. The relationship between management goals, implemented innovations, and management objects is determined and presented in the form of an ontological model. Conclusions. Development of an ontological model makes it possible not only to determine the relationship between various elements of economic, scientific, technical, and innovation activities of a construction company, but also to develop approaches to assessing their quality and building an innovation management system. Further research should focus on the aspects of innovation implementation at construction enterprises, its technological features, and processes that can be transformed for the successful implementation of these innovations.
Relationship between a Reduced Aroma Production and Lipid Metabolism of Apples after Long-term Controlled-atmosphere Storage

Field: Agricultural and Biological Sciences (Life Sciences)

`Golden Delicious' apples (Malus domestica Borkh.) harvested at the preclimacteric and climacteric stages of ripening were stored for up to 8 months at 1C in air and under various controlled atmosphere(s) (CA), including ultralow oxygen (ULO) storage conditions. Aroma volatiles were measured at 2-month intervals in fruit ripened for 10 days at 20C. Fruits harvested at the climacteric stage produced more volatiles during all storage conditions than preclimacteric fruit. All CA storage treatments suppressed aroma production compared to cold storage. The greatest reduction was found under ULO (1% O 2 ) and high CO 2 (3%) conditions. A partial recovery of aroma production was observed when CA fruits were subsequently stored for 14 days under cold storage conditions. Suppression of aroma production under ULO conditions seems to be related to low fatty acid synthesis and/or degradation, and is restricted to volatiles having a straight C chain. Production of branched C-chain aroma compounds was suppressed by high CO 2 concentrations. The reduced capacity of aroma production during shelf life after ULO storage is confined to apple cultivars producing mainly ester compounds with a straight C-chain, e.g., `Golden Delicious'.
DOAS measurements of NO2 and H2CO at Kinshasa and Comparisons with Satellites Observations

Field: Environmental Science (Physical Sciences)

&lt;p&gt;Africa experiences a fast urban inhabitants growth, caused by the largest population boom in the world, combined with rural exodus. Many cities are heavily affected by air pollution. It is therefore essential to monitor the concentrations of the various polluting species such as NO&lt;sub&gt;2&lt;/sub&gt;, HCHO, O&lt;sub&gt;3&lt;/sub&gt; and aerosols, which have a direct impact on the population health. The sources of pollutant in Africa are different from those found in Europe. For example, forest fires and household cooking largely contribute to the NO&lt;sub&gt;2&lt;/sub&gt; and HCHO burdens in Central Africa. However, many large African cities, such as the City of Kinshasa, capital of the Democratic Republic of Congo, do not have atmospheric measurement instruments.&lt;/p&gt;&lt;p&gt;In order to tackle the lack of measurements in Kinshasa, the Royal Belgian Institute of Space Aeronomy (BIRA-IASB) has, in collaboration with the University of Kinshasa (UniKin), installed an optical remote sensing instrument on the UniKin site (-4.42&amp;#176;S, 15.31&amp;#176;E). Installed in May 2017, the instrument has been in operation until today and provides data to measure the column amounts &amp;#160;of several polluting species in the atmosphere of Kinshasa. The instrument is based on a compact AVANTES &amp;#160;spectrometer covering the spectral range 290 - 450 nm with 0.7 nm resolution. The spectrometer is a Czerny-Turner type with an entry slit of 50 &amp;#956;m wide, and an array of 1200 l/mm. A 10 m long and 600 &amp;#956;m diameter optical fiber is connected to the spectrometer to receive the incident light beam from the sky. Measurements were mainly made by looking in a fixed direction until November 2019. Since then, a Multi-Axis geometry (MAX-DOAS) has been implemented.&lt;/p&gt;&lt;p&gt;The measurements provided by this DOAS instrument allowed us to start studying the atmosphere of Kinshasa using the QDOAS software, which allows us to find the oblique columns of different observed species.&amp;#160; This poster will present the instrument, the database and &amp;#160;the procedure used to convert these oblique columns into vertical columns, using the air mass factors calculated with the radiative transfer model. We also present our first MAX-DOAS results, analyzed using the retrieval tools of the ESA FRM4DOAS project. The study of current results clearly shows the signature of polluting species such as NO&lt;sub&gt;2&lt;/sub&gt;, HCHO in the atmosphere of Kinshasa. We also use simulations by the GEOS-Chem chemistry transport model to evaluate the magnitude of the emissions needed to explain the observed column amounts. These observations made in Kinshasa could contribute to the validation of satellite products and the refinement of models. We present a first comparison of Kinshasa's ground-based observations with those of the OMI and TROPOMI satellites&lt;/p&gt;
LBODP092 Proposal Of Indication For Completion Thyroidectomy In Follicular Thyroid Carcinoma Using TERT Promoter Mutational Status

Field: Medicine (Health Sciences)

Abstract Background Stepwise surgical approach with hemithyroidectomy and completion thyroidectomy was used to solve the dilemma of definite characterization of follicular thyroid carcinoma (FTC). However, which patients will be candidates for completion thyroidectomy has been controversial. The aim of this study is to clarify the selection criteria for completion thyroidectomy using TERT promoter mutation. Methods A total of 87 FTC patients who had information about TERT promoter mutation from August 1995 to November 2020 were investigated. The cumulative risk of initial distant metastasis, disease recurrence, and cancer-specific death according to primary tumor size in each of the WHO 2017 classifications were calculated. Results Of the 87 patients, 8 patients (9.2%) had initial distant metastasis, and 15 patients (17.2%) had persistent disease or developed structural recurrence. Threshold diameter for initial distant metastasis, disease recurrence, and cancer-specific death was 2cm in minimally invasive FTC (MI-FTC) with mutant TERT (M-TERT) and in encapsulated angioinvasive FTC (EA-FTC) with M-TERT, while in MI-FTC with wild-type TERT (WT-TERT) and EA-FTC with WT-TERT it was 4cm. Cumulative risk of initial distant metastasis, disease recurrence, and cancer-specific death according to primary tumor size in each WHO 2017 classification were significantly different only in patients with WT-TERT (P = 0. 001, P = 0. 019, and P = 0. 005, respectively). Conclusions The data suggested that 2 cm may be a critical threshold diameter for deciding completion thyroidectomy in MI-FTC with M-TERT and EA-FTC with M-TERT. TERT promoter mutational status can be a game changer for selecting candidates for completion thyroidectomy. Presentation: No date and time listed
BMA secretary's reply

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Primary cultured bovine brain microvessel endothelial cells (BBMECs), were used as an in vitro model of the blood-brain barrier to examine the involvement of eicosanoids in the permeability and cytoskeletal structural changes observed following exposure to tumor necrosis factor-α (TNF-α). Compared with control monolayers, BBMECs exposed to TNF-α formed actin filament tangles and extracellular gaps with a resultant increase in permeability. Both the permeability and cytoskeletal changes observed with TNF-α were significantly reduced following pretreatment with NS-398 or indomethacin, inhibitors of cyclooxygenase (COX). Western blot analysis showed that TNF-α had no apparent effect on the expression of COX-1, but did induce the expression of COX-2 in the BBMECs. The induction of COX-2 expression occurred within the same time frame (2–4 h following TNF-α exposure) as the permeability increases observed with the cytokine. Consistent with the increased expression of COX-2, BBMEC monolayers exposed to TNF-α had significantly greater secretion and release of prostaglandin E2 (PGE2) and prostaglandin F2α (PGF2α). Furthermore, BBMEC monolayers treated with PGE2 or PGF2α showed significant increases in permeability and cytoskeletal structural changes when compared with control monolayers. Together, these results suggest that the TNF-α-induced permeability and cytoskeletal structural effects are due, in part, to an induction of the COX-2 system and increased release of prostaglandins in the cerebral microvasculature.
Antimicrobial Suscepitibility Test of MTT Detection in Cow Mastitis

Field: Veterinary (Health Sciences)

In order to compare MTT method and traditional disc agar diffusion test,nine kinds of antibiotics-Amikacin,rimethoprim and sulphame-thoxazole,Fluperacid,Gentamycin,Cefotaxime,Cefazolin sodium,Ampicillin and Streptomycin were used.The result showed that bacteria in milk samples were tolerance to streptomycin,erythromycin,trimethoprim and sulphame-thoxazole,were moderate sensitivity to Gentamycin and Amikacin,were sensitivity to Ampicillin,Cefotaxime and Cefazolin sodium besides Fluperacid.These two methods had same result.Therefore it can be concluded that MTT test may be used to make antibiotic susceptibility test to detect cow mastitis.