MP38-10 25-YEAR TRENDS IN STAGE-SPECIFIC INCIDENCE RATES FOR BLADDER CANCER IN A LARGE STATEWIDE REGISTRY

Field: Medicine (Health Sciences)

You have accessJournal of UrologyBladder Cancer: Epidemiology & Evaluation I (MP38)1 Sep 2021MP38-10 25-YEAR TRENDS IN STAGE-SPECIFIC INCIDENCE RATES FOR BLADDER CANCER IN A LARGE STATEWIDE REGISTRY Justin Loloi, Yu-Kuan Lin, Fabian Camacho, Eugene Lengerich, and Jay Raman Justin LoloiJustin Loloi More articles by this author , Yu-Kuan LinYu-Kuan Lin More articles by this author , Fabian CamachoFabian Camacho More articles by this author , Eugene LengerichEugene Lengerich More articles by this author , and Jay RamanJay Raman More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002053.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Bladder cancer (BC) is a common genitourinary malignancy with over 80,000 new cases diagnosed annually and over 17,000 associated deaths. We review 25-years of BC incidence (1993-2017) within the state of Pennsylvania to better define incidence, geographic distribution, and trends over time. METHODS: The Pennsylvania Cancer Registry was reviewed for statewide and component county age-adjusted BC incidence rates and stage distribution. Chloropleth maps plotting statewide and county-specific incidence rates across time were created using the GeoDa statistical package. RESULTS: 93,476 cases of BC were recorded in Pennsylvania from 1993 to 2017. Over 95% of patients were older than 50 years of age, 95% were white race, and three-quarters were male. SEER summary staging distribution included 42.3% in situ, 42.3% local, 7.1% regional, 3.7% distant, and 4.6% unstaged. Age-adjusted annual rates of BC over the study interval were stable at 24.5 patients per 100,000 (range, 22.7–25.6) However, annual rates of distant disease increased from 0.5 to 1.1 patients per 100,000 (p<0.001) with an average percent change increase of 6.6% over the study interval. The annual percent distribution of distant disease doubled from 2.3% to 5.1% (p<0.001) with a greater increase in women compared to men. (Figure 1) Chloropleth maps highlighted growing “hot spots” of bladder cancer incidence in the northwestern, northeastern, and southeastern portions of the state. (Figure 2) CONCLUSIONS: BC incidence in the state of Pennsylvania has remained relatively stable over the past 25 years. There was, however, a concerning 6% annual percentage increase in distant disease over the study period. Geospatial investigation implicates growing “hot spots” of BC in the certain portions of the state. The underlying cause for these trends requires further investigation. Source of Funding: None © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e697-e698 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Justin Loloi More articles by this author Yu-Kuan Lin More articles by this author Fabian Camacho More articles by this author Eugene Lengerich More articles by this author Jay Raman More articles by this author Expand All Advertisement PDF downloadLoading ...