jimnoneill/paper-to-field-training huggingface dataset:
CURRENT STAGE OF DEVELOPMENT OF PERSONALITY IDENTIFICATION EXAMINATION BASED ON APPEARANCE (FACIAL IDENTIFICATION)

Field: Social Sciences (Social Sciences)

The article presents the results of a theoretical analysis of the current state of examination of personality identification based on appearance. The question of changing the object of research in the specified examination was raised. It has been established that with the development of digital technologies, multi-angle facial images began to prevail as an object of research, and studies of video recordings are widespread. The different position of the head in the studied images led to the impossibility of using a significant number of comparative research methods: alignment along the medial line, alignment along a broken line, image editing, applications, “masks”, overlaying translucent images, comparison of relative values, overlay of coordinate grids, construction of geometric shapes. The transformation of research objects necessitates a change in the methods of comparative research. It is indicated that with the proliferation of video images, the identification capabilities of the examination have increased: an expert can examine images of an identifiable person on the entire video sequence. A common disadvantage of video recordings is image quality. For research, video recordings from external video surveillance cameras are often received, but the purpose of installing such cameras is to fix the environment, and not the faces of people. This explains the poor image quality. A frequent problem in carrying out examinations for the identification of a person by signs of appearance is the “recognition effect”. At the first glance at the image, one may get the impression that it is suitable for identification in the framework of portrait examination. However, this impression is most often mistaken. Often people have a sense of the obviousness of the image of a particular person in the frame if they have experience of interaction with this person. In addition, upon a detailed study of the image, an expert may conclude that it is unusable. The captured signs of appearance do not always constitute the necessary complex for the possibility of conducting research. The current state of examination in identifying a person based on appearance suggests the need to develop comparison methods that could take into account the difference in the angles of the people under study. These methods include a graphical identification algorithm, a method of dimensional ratios of individual elements of appearance, and mathematical research methods. Further development in these areas is promising for expanding the possibilities of carrying out facial identification.
Quasi-Birth-and-Death Processes, Lattice Path Counting, and Hypergeometric Functions

Field: Mathematics (Physical Sciences)

In this paper we consider a class of quasi-birth-and-death processes for which explicit solutions can be obtained for the rate matrix R and the associated matrix G . The probabilistic interpretations of these matrices allow us to describe their elements in terms of paths on the two-dimensional lattice. Then determining explicit expressions for the matrices becomes equivalent to solving a lattice path counting problem, the solution of which is derived using path decomposition, Bernoulli excursions, and hypergeometric functions. A few applications are provided, including classical models for which we obtain some new results.
Sensory Evaluation of a Teff and Dairy-Enriched Flatbread and Sustainable Development Goals of the United Nations

Field: Agricultural and Biological Sciences (Life Sciences)

Teff has a potential to contribute to Sustainable Development Goals (SDG) of the United Nations, particularly goals number SDG1 (no poverty), SDG2 (zero hunger) and SDG3 (good health and well-being). Adding fermented-dairy products such as yogurt may have a counter-effect on the activity phytates in teff-enriched bread products. The objective of this current pilot sensory evaluation study was to evaluate whether a teff and dairy-enriched flatbread (yogurt or milk) would receive a higher acceptance among students, faculty, and staff of the College of Health Sciences at West Chester University of Pennsylvania. Texture, taste, moisture, color, and aftertaste were evaluated using a 9-point hedonic scale for a regular (0T), a Teff and Milk (TMF) enriched (15% teff dry basis), and a Teff and Yogurt (TYF) enriched flatbread samples. An 18-component questionnaire (included demographics) was administered. Fifty-nine percent of respondents were female, 41% were male, 82.5% were white, and 82% were between the ages of 18-30 years. Ninety-seven percent of them were familiar and enjoyed flatbread. There was no significant (p<0.05) difference between the scores for texture, taste, color, and aftertaste of all three bread samples. However, the moisture of the TMF bread was liked most (p<0.05). Overall, 44% of participants preferred the TMF bread followed by the TYF bread (35%) and 0T (21%). Further investigation using objective tests will help with the optimization process of the TMF and TYF.
Willingness to self-disclose cyber victimization to friends or parents: Gender differences in cyber victimization a year later

Field: Psychology (Social Sciences)

As computer access and use continue to expand for increasingly younger children, online social settings will continue to provide a prominent platform for children to experience victimization. Of particular interest to the present research was children’s (222 children, boys = 105; girls = 117) willingness to tell a friend and willingness to tell a parent about experiences of cyber victimization (Grades 3 and 4). This self-disclosure was then examined in relation to cyber victimization a year later (Grades 4 and 5), controlling for initial levels of cyber victimization at Time 1 and cyber usage at Time 1 and Time 2. For boys, willingness to tell a friend at Time 1 about cyber victimization was associated with less cyber victimization at Time 2 than not being willing to tell a friend. For girls, willingness to tell a parent at Time 1 about cyber victimization was associated with less cyber victimization at Time 2 than not being willing to tell a parent. These findings underscore the possible importance of willingness to self-disclose as a coping strategy to reduce future incidences of cyber victimization and highlight the complexity of this strategy in terms of gender and nature of social support.
Moving Averages: Real-Time Data Monitoring in the Clinical Chemistry Laboratory

Field: Health Professions (Health Sciences)

Laboratorians are well accustomed to the practice of quality control (QC) with Levy-Jennings plots, both prior to and following analytical runs.One limitation of Levy-Jennings plots is that they represent QC at a single moment in time and are insensitive to error between QC runs.Currently, laboratory information systems, middleware systems, and laboratory instruments themselves offer limited options for real-time data monitoring (RTDM) and data exploration in clinical chemistry.In addition, these solutions are often proprietary, difficult to customize, structurally isolated to single vendors, and do not extend throughout the breadth of the clinical laboratory.Our purpose was to design and implement a technology-agnostic quality assurance framework, developed in our institution, to allow RTDM via moving average calculations.The moving averages platform was based on nonrelational (NoSQL), or document-oriented, database technology (elasticsearch, Los Altos, CA).The framework was hosted on a Windows-based machine (Microsoft, Redmond, WA).Deidentified laboratory data for testing were obtained via static data export from the Epic Clarity database and will soon be implemented with an HL7 interface for live streaming data.These data were stored within the NoSQL database to allow for rapid scaling and analytics.This approach allowed for successful implementation of a web-based application with a dashboard of moving average charts of individual chemistry assay components.Testing demonstrated a minute-wise moving average calculation for >400,000 chemistry results in a 30-day time period could be completed in less than 2 milliseconds.Moving average parameters are adjustable by the end user depending on the component being monitored.These parameters include movingaverage calculation methods, chemistry component, expected normal ranges, number of samples used to calculate moving average, and time resolution.As a result, this has provided our institution with the capability of RTDM for chemistry assays.RTDM and quality assurance tools are widely used in other industries and historically have seen a slow migration into health care and the clinical laboratory practices.While Levy-Jennings plots have shown the ability to detect systematic and random errors, they do so only at isolated moments in time.RTDM with
Potent activity of 2'-beta-fluoro-2',3'-dideoxyadenosine against human immunodeficiency virus type 1 infection in hu-PBL-SCID mice

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

A new antiretroviral agent, 2'-beta-fluoro-2',3'-dideoxyadenosine (FddA), is an acid-stable compound whose triphosphate form is a potent reverse transcriptase inhibitor with in vitro anti-human immunodeficiency virus (HIV) activity and a favorable pharmacokinetic profile. Severe combined immunodeficiency (SCID) mice reconstituted with human peripheral blood leukocytes (hu-PBL-SCID mice) provide a useful small-animal model for HIV research. In the present study we utilized this experimental system for the in vivo evaluation of the anti-HIV activity of this new compound when administered prior to infection. Initial studies revealed that, following a challenge with 50 100% tissue culture infective doses of HIV type 1 lymphadenopathy-associated virus, 39 of 42 (93%) control mice developed HIV infection, as evidenced by positive coculture or positive PCR. Administration of zidovudine decreased the infection rate to 5 of 16 (31%), while administration of FddA decreased the infection rate to 0 of 44 (0%). In follow-up controlled studies, the anti-HIV activity of FddA was confirmed, with 18 of 20 control mice showing evidence of HIV infection, compared with 4 of 20 FddA-treated mice. In addition to having direct anti-HIV effects, FddA was found to have a protective effect on human CD4+ T cells in the face of HIV infection. Mice treated with FddA were found to have a significantly higher percentage of CD4+ T cells than controls (10.3% +/- 3.4% versus 0.27% +/- 0.21%; P = 0.01). Thus, FddA, with its potent anti-HIV activity in vivo, high oral bioavailability, long intracellular half-life, and ability to preserve CD4+ cells in the presence of HIV, appears to be a promising agent for clinical investigation.
Highly ABA-Induced 1 (HAI1)-Interacting protein HIN1 and drought acclimation-enhanced splicing efficiency at intron retention sites

Field: Agricultural and Biological Sciences (Life Sciences)

The Highly ABA-Induced 1 (HAI1) protein phosphatase is a central component of drought-related signaling. A screen for HAI1-interacting proteins identified HAI1-Interactor 1 (HIN1), a nuclear protein of unknown function which could be dephosphorylated by HAI1 in vitro. HIN1 colocalization and interaction with serine-arginine rich (SR) splicing factors and appearance of nuclear speckle-localized HIN1 during low water potential (ψ w ) stress suggested a pre-mRNA splicing-related function. RNA sequencing of Arabidopsis Col-0 wild type identified more than 500 introns where moderate severity low ψ w altered intron retention (IR) frequency. Surprisingly, nearly 90% of these had increased splicing efficiency (decreased IR) during stress. For one-third of these introns, ectopic HIN1 expression ( 35S:HIN1 ) in unstressed plants mimicked the increased splicing efficiency seen in stress-treated wild type. HIN1 bound to a GAA-repeat, Exonic Splicing Enhancer-like RNA motif enriched in flanking sequence around HIN1-regulated introns. Genes with stress and HIN1-affected splicing efficiency were enriched for abiotic stress and signaling-related functions. The 35S:HIN1 plants had enhanced growth maintenance during low ψ w , while hin1 mutants had reduced growth, further indicating the role of HIN1 in drought response. HIN1 is annotated as an MYB/SANT domain protein but has limited homology to other MYB/SANT proteins and is not related to known yeast or metazoan RNA-binding proteins or splicing regulators. Together these data identify HIN1 as a plant-specific RNA-binding protein, show a specific effect of drought acclimation to promote splicing efficiency of IR-prone introns, and also discover HAI1–HIN1 interaction and dephosphorylation that connects stress signaling to splicing regulation.
A phase II study of osimertinib for patients with radiotherapy-naïve CNS metastasis of non-small cell lung cancer harboring EGFR mutations: The OCEAN study (LOGIK 1603/WJOG 9116L).

Field: Medicine (Health Sciences)

9597 Background: Approximately 15%–30% of patients treated with EGFR-TKIs experience central nervous system (CNS) progression. Although radiotherapy is a standard treatment for CNS metastasis, the efficacy of radiotherapy against CNS is poor. The aim of OCEAN study was to assess the efficacy of osimertinib for patients with radiotherapy-naïve CNS metastasis of NSCLC harboring EGFR mutations. Methods: OCEAN study was two-cohort phase II trial, 65 patients (T790M cohort; 40 patients and first-line cohort; 25 patients) with radiotherapy-naïve CNS metastasis of EGFR mutation-positive NSCLC was included. Patients were treated with osimertinib 80 mg once daily. The primary endpoint was the response rate of brain metastasis (BMRR) assessed by the PAREXEL criteria. We set a threshold value of 50% and an expected value of 70% based on the overall response rate (ORR) of AURA trial. Based on one-sided alpha = 0.05 and power = 0.8, the sample size of T790M cohort was calculated to be 40. Key secondary endpoints were progression-free survival (PFS), and ORR, BMRR assessed by the RECIST criteria. We are exploratorily assessing the blood concentration of osimertinib at day 22, which considered to represent steady state. In this report, we present the results of T790M cohort. Results: Between October 2016 to July 2019, 40 participants were recruited in the T790M cohort. The median age was 66.5 with 30.0% male. Eight patients had symptomatic CNS metastasis and most patient had multiple CNS metastasis (77.5%). BMRR assessed by PAREXEL criteria was 66.7% (95%CI: 54.3 – 79.1%) and BMRR assessed by RECIST was 70.0% (95%CI, 49.9 – 90.1%). Median PFS was 7.1 months (95%CI, 3.4 – 13.6 months) and ORR assessed by RECIST was 40.5% (95%CI, 24.7 – 57.9%). Treatment related pneumonitis was observed in 4 patients (10.0%). There was no grade 3 or higher toxicities that were found in more than 10%. Conclusions: This first study assessed the efficacy of osimertinib for patients with radiotherapy-naïve CNS metastasis of EGFR T790M mutation-positive NSCLC. The OCEAN study met primary endpoint. The results of this study suggested that patients with brain metastasis harboring EGFR T790M mutations had better to receive osimertinib prior to brain radiotherapy. Clinical trial information: 071180017 .
Entire solutions of multivalued nonlinear Schrodinger equations in Sobolev spaces with variable exponent

Field: Mathematics (Physical Sciences)

We establish the existence of an entire solution for a class of stationary Schrödinger equations with subcritical discontinuous nonlinearity and lower bounded potential that blows-up at infinity. The abstract framework is related to Lebesgue-Sobolev spaces with variable exponent. The proof is based on the critical point theory in the sense of Clarke and we apply Chang's version of the Mountain Pass Lemma without the Palais-Smale condition for locally Lipschitz functionals. Our result generalizes in a nonsmooth framework a result of Rabinowitz on the existence of ground-state solutions of the nonlinear Schrödinger equation.
Pengaruh Pemberian Jus Jambu Biji Merah Terhadap Kadar Hemoglobin Pada Penderita Anemia Remaja Putri di SMK Bunga Persada Cianjur Tahun 2022

Field: Medicine (Health Sciences)

Young women are prone to anemia due to lack of nutrient intake. Anemia is one of the most common health problems in the world today, especially in young women. The impact of anemia can cause weakness, lethargy, and the face becomes pale. So it needs to be handled, one of which is by means of non pharmacological prevention efforts, namely giving red guava juice. The purpose of this study was to determine whether or not there was an effect of giving red guava juice on hemoglobin levels in young women at SMK Bunga Persada Cianjur. This research method uses a quasy experimental research design with a one group pre test – post test design with a purposive sampling model. The result of the study on 17 young female respondents found that the average Hb before being given red juice was 11,5 gr/dl. The average after being given red guava juice is 13,0 gr/dl. So it can be concluded that there is an effect of giving red guava juice with an increase in Hb in anemia sufferers of young women based on the results of data processing using the paired t – test with the results obtained that there is an effect with a value (p value 0,000) (<0,005).
Genetic Epidemiology of Subclinical Cardiovascular Disease and Osteoporosis Indices in African Ancestry Families

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Cardiovascular disease (CVD) is a major public health concern, especially in African ancestry populations, which have greater risk compared with Caucasians. Subclinical CVD measures provide information on the health of the vasculature and are predictive of future risk of clinical events. Vascular health indices have been associated with lower bone mineral density (BMD) and osteoporosis suggesting a potential common etiology. Intima-media thickness (IMT) and arterial diameter (adventitial diameter [AD] and lumen diameter [LD]) are subclinical CVD measures obtained by carotid ultrasound, whereas pulse pressure (PP) and pulse-wave velocity (PWV) are subclinical measures of arterial stiffness. The genetic influence on these subclinical CVD measures and in the link between CVD and osteoporosis has not been well defined in African ancestry populations. Therefore, we have estimated genetic heritability, genetic correlation of CVD and osteoporosis related traits, and performed univariate and bivariate genome-wide linkage analysis of these traits in 7 large, multigenerational families of African ancestry from the Caribbean island of Tobago. A total of 461 individuals aged ¡Ý18 years were included in these analyses from probands and families who were recruited without regard to their health status. After removing the effects of covariates, subclinical CVD traits were all heritable and there was significant phenotypic and genetic correlation between CVD and osteoporosis related traits. The most promising evidence of linkage was detected for AD-BMD trait-pairs on chromosome 14 (max LOD=5.2) in bivariate analysis and for AD and LD on chromosome 11 (max LOD=4.1) in univariate analysis. The linkage regions contain several genes known to be involved in cardiovascular disease including the ApoA1/C3/A4/A5 gene cluster, IL18, BMP4, and ESR2. Further studies of these regions may reveal novel insight into the genetic regulation of subclinical CVD and osteoporosis. These findings have public health significance because determining the genetic regulation of chronic disease may aid in risk prediction and, ultimately, minimize health disparities in African ancestry populations.
Synthesis and characterisations of temperature-responsive drug delivery hydrogel for medical applications

Field: Materials Science (Physical Sciences)

The imiquimod-MEO 2 MA hydrogel film was fabricated as a drug release pad for the keloid therapy in this research. The physiochemical properties of the synthesised MEO 2 MA hydrogel, including swelling/deswelling behaviour and temperature response, were characterised to understand the loaded amount and released speed of the imiquimod. Similarly, the cytotoxicity of developed hydrogel pad was measured to understand the biological properties for the keloid therapy treatment.
Chemoembolization of Hepatic Malignancies

Field: Medicine (Health Sciences)

Transarterial chemoembolization is a therapy that has been used since the early 1980s for liver cancer that involves delivery of chemotherapeutic agents into the hepatic artery. There are randomized controlled trials showing increased survival of patients undergoing transarterial chemoembolization versus supportive care; in fact, transarterial chemoembolization is considered the standard of care for intermediate stage hepatocellular carcinoma that is not surgically resectable. Transarterial chemoembolization is being used to treat metastatic disease to the liver as well; primary cancers include colorectal cancer, ocular melanoma, neuroendocrine cancer, and renal cell cancer. Although there are no randomized controlled trials, there are good survival data and few side-effects of transarterial chemoembolization in these instances.
Comparative Evaluation of the Efficacy of Different Ni-Ti Rotary Instruments in Removal of Gutta-Percha During Root Canal Retreatment: An in vitro Study

Field: Dentistry (Health Sciences)

Aim: An assessment and comparison of three retreatment files was conducted to determine their effectiveness in the retrieval of gutta-percha. Materials and Method: In the investigation, 60 extracted single-rooted human teeth having straight canals and complete apices were used. The ProTaper Universal file system was used to prepare teeth and obturated using gutta-percha with sealant AH Plus utilizing down pack and backfill obturation technique. Removal was performed with ProTaper, D-RaCe files, MTwo, and R-Endo retreatment files. Using a stopwatch, the time needed to take out the GP was also calculated in seconds. We used ANOVA along with the post hoc Tukey’s test to analyze the quantity of obturating material in apical, middle, and coronal third following decoronation and longitudinal splitting. Results: The average percentage of gutta-percha points removed across root levels varied significantly among the ProTaper, D-RaCe MTwo, and R-Endo groups. With the exception of the ProTaper group, when the middle level displayed the most removal, the coronal level showed much higher removal than the mid-root level, while the apical level often exhibited the highest removal. Conclusion: ProTaper retreatment files outperformed MTwo, D-RaCe, and R-Endo among the four groups in terms of removing root canal filling material. However, none of the experimental groups removed gutta-percha completely from root canals.
Laryngeal vibratory behavior in traditional Noh singing

Field: Health Professions (Health Sciences)

The phonation of Noh, a traditional Japanese style of singing, was investigated using electroglottographic and acoustical analyses. The dynamics of the laryngeal vibratory behaviors were analyzed for the singing voice of the Noh play compared with natural speech based on the Electroglottography (EGG) parameters, EGG waveform, spectrum, and spectrogram. The result shows that Noh singing is characterized by low open quotient and high speed quotient. Three types of phonations are used in the singing with pressed, Vocal-Ventricular Mode (VVM), and growl voices. It was hypothesized that the period doubling observed in the EGG signal was reflective of VVM, which was caused by the phase difference in the vocal and ventricular fold oscillations, while the damped peak amplitude in every other cycle in the EGG signal was the result of the oscillations of the aryepiglottic folds at a frequency of half of the fundamental frequency. Sub-harmonics generated by the supraglottal oscillations add unique timbre to the sounds. The results suggest that the combination of phonation types is the key factor in generating their peculiar voice qualities.