jimnoneill/paper-to-field-training huggingface dataset:
A Skin Lesion in a Patient from Kentucky

Field: Medicine (Health Sciences)

Diagnosis: Southern tick-associated rash illness (STARI). STARI manifests as a skin lesion (figure 1) and is considered indistinguishable from erythema migrans, a characteristic skin manifestation of Borrelia burgdorferi infection (Lyme disease) [1-4]. As was the case with our patient, some patients with STARI recall that the rash was preceded by the bite of an Amblyomma americanum tick, also known as the lone star tick because of the appearance of a distinctive white spot on the dorsal surface of the adult female of this species (figure 2). The adult male and the nymph (figure 3) of this tick do not manifest this spot. Borrelia lonestari, a species phylogenetically distinct from B. burgdorferi, is considered to be a possible etiologic agent for this illness, on the basis of its identification by PCR in ~2% of A. americanum ticks from many locations in the southeastern and south-central United States [5-7]. In a single case, DNA of B. lonestari was amplified from both the erythema migranslike skin lesion and the associated A. americanum tick [6]. However, Wormser et al. [8; in this issue] studied skin biopsy specimens from 30 patients from Missouri with erythema Figure 2. An adult female Amblyomma americanum tick
Practice and Discussion of Project Teaching in the Professorship Universities and Colleges' Course Teaching Course

Field: Social Sciences (Social Sciences)

Professorship education is to regard training applied talents of technology as the basic goal,is trained and met the special education of demand talents of the trade.And it is to train the applied talent's most favorable means that the professorship universities and colleges adopt project teaching.This text has carried on the discussion to practice in the course of teaching of teaching method of the project.
What students and teachers can learn by judging a book by its cover

Field: Arts and Humanities (Social Sciences)

Teacher librarians and English teachers have numerous opportunities to engage students and achieve successful learning outcomes in a number of key curriculum areas. Using and recounting a brief history of the cover for a teen thriller written by Australian author Justine Larbalestier in 2009, this article highlights discussion points concerning book covers and suggests ways in which book covers for children and young people can be explored in both library and classroom settings.
BORON NEUTRON CAPTURE THERAPY

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

RETURN TO ISSUEPREVNewsNEXTBORON NEUTRON CAPTURE THERAPYBoron-rich porphyrin compound holds promise for treating cancerMICHAEL FREEMANTLECite this: Chem. Eng. News 2002, 80, 34, 13Publication Date (Print):August 26, 2002Publication History Published online13 November 2010Published inissue 26 August 2002https://pubs.acs.org/doi/10.1021/cen-v080n034.p013https://doi.org/10.1021/cen-v080n034.p013newsACS PublicationsCopyright © 2002 AMERICAN CHEMICAL SOCIETYArticle Views25Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Boron,Cancer therapy,Cells Get e-Alerts
[Traumatism among the milk industry workers in the Saratov district].

Field: Health Professions (Health Sciences)

A study of socio-hygienic aspects of occupational injuries at milk industry enterprises of Saratov region in 1977-1986 was carried out and an analysis was provided of non-occupational injuries at the main enterprise of the industry--the Saratov cheese-and-butter storage house during 1983-1985.
Characterization of Baseline Thrombopoietin Levels in Patients With Chronic Liver Disease: Results From 2 Pooled Clinical Studies in Patients With Thrombocytopenia and Liver Disease

Field: Medicine (Health Sciences)

Introduction: Patients with chronic liver disease (CLD) commonly develop thrombocytopenia (TCP). Thrombopoietin (TPO) is a cytokine that normally regulates megakaryocyte and platelet production, and is primarily produced in the liver. Because of the progressive destruction and regeneration of liver parenchyma that lead to fibrosis and cirrhosis, patients with liver disease have been shown to have decreased levels and/or activity of TPO. However, little is known about the correlation between TPO levels and the severity of TCP, the etiology of CLD, or the presence of hepatic decompensation. In this analysis, we focused on the Baseline TPO levels from 2 pooled studies evaluating the use of the TPO-receptor agonist avatrombopag in patients with CLD and TCP. Methods: Two randomized, double-blind, placebo-controlled Phase 3 trials (ADAPT-1 & ADAPT-2) enrolled adults with CLD and Baseline platelet counts (PC) <50x109/L, who were scheduled to undergo a procedure. Patients were divided into 2 cohorts based on Baseline PC (COHORT 1- PC<40x109/L [N=251]; COHORT 2- PC 40 to <50x109/L [N=184]). For this analysis, TPO levels reported at Baseline (pretreatment) were characterized for each cohort based on HCC status, MELD, CTP, and liver disease etiology. Results: For the overall population, Baseline TPO levels were 126.9 ng/L for COHORT 1 and 116.0 ng/L for COHORT 2. In COHORT 1, a trend towards lower TPO levels was observed in patients with worsening MELD scores. A similar trend was observed with worsening CTP class in COHORT 1. In COHORT 2, the higher Baseline PC cohort, no trend in TPO levels was observed with increasing MELD or worsening CTP class; the presence of HCC also did not impact TPO levels for either cohort. While differences in TPO levels were observed for the various etiologies of liver disease (alcoholic, chronic viral hepatitis, nonalcoholic steatohepatitis), no consistent trend was noted. Conclusion: The biology of TPO metabolism in advanced liver disease is complex and appears to be influenced by both platelet count and degree of liver failure. We hypothesize that the mechanism involves changes in feedback regulation of TPO levels in addition to impaired hepatic synthesis. When platelets are severely reduced (<40x109/L), TPO levels become almost entirely dependent on liver synthetic capacity and there is loss of TPO regulatory pathway activity.877 Figure 1 No Caption available.
Improved Ant Colony Clustering Algorithm and Its Performance Study

Field: Computer Science (Physical Sciences)

Clustering analysis is used in many disciplines and applications; it is an important tool that descriptively identifies homogeneous groups of objects based on attribute values. The ant colony clustering algorithm is a swarm-intelligent method used for clustering problems that is inspired by the behavior of ant colonies that cluster their corpses and sort their larvae. A new abstraction ant colony clustering algorithm using a data combination mechanism is proposed to improve the computational efficiency and accuracy of the ant colony clustering algorithm. The abstraction ant colony clustering algorithm is used to cluster benchmark problems, and its performance is compared with the ant colony clustering algorithm and other methods used in existing literature. Based on similar computational difficulties and complexities, the results show that the abstraction ant colony clustering algorithm produces results that are not only more accurate but also more efficiently determined than the ant colony clustering algorithm and the other methods. Thus, the abstraction ant colony clustering algorithm can be used for efficient multivariate data clustering.
Ts fuzzy robust sampled-data control for nonlinear systems with bounded disturbances

Field: Computer Science (Physical Sciences)

\n\t\t\t\t\t<jats:p>We investigate robust fault-tolerant control pertaining to Takagi&ndash;Sugeno (TS) fuzzy nonlinear systems with bounded disturbances, actuator failures, and time delays. A new fault model based on a sampled-data scheme that is able to satisfy certain criteria in relation to actuator fault matrix is introduced. Specifically, we formulate a reliable controller with state feedback, such that the resulting closed-loop-fuzzy system is robust, asymptotically stable, and able to satisfy a prescribed H&infin; performance constraint. Linear matrix inequality (LMI) together with a proper construction of the Lyapunov&ndash;Krasovskii functional is leveraged to derive delay-dependent sufficient conditions with respect to the existence of robust H&infin; controller. It is straightforward to obtain the solution by using the MATLAB LMI toolbox. We demonstrate the effectiveness of the control law and less conservativeness of the results through two numerical simulations.</jats:p>\n\t\t\t\t
CSD 891236: Experimental Crystal Structure Determination

Field: Chemistry (Physical Sciences)

An entry from the Inorganic Crystal Structure Database, the world’s repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the joint CCDC and FIZ Karlsruhe Access Structures service and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Tuning architecture at run-time

Field: Computer Science (Physical Sciences)

We describe the structure and operational mode of a coprocessor system which, when incorporated in a microprogrammed syetem to carry out Dynamic Vertical Migration, improves execution speed for any program. The coprocessor includes an interconnection mechanism between the machine code and the instruction set microcode. The interconnections (Intermediate instructions) are created in parallel with machine instruction execution and so do not increase normal execution time. This intermediate code is stored dynamically in coprocessor memory, saving the fetching and decoding phases in subsequent executions, speeding up the execution of repetitive machine code.The coprocessor structure is organized around three basic elements: Interconnection Memory, Interconnection Memory Management Unit and Coprocessor Control Unit. A software simulator has been developed to analyse coprocessor behaviour and a theoretical model has been formulated from the results ot these analyses.
Experimental evaluation of a hybrid thoracic aortic prosthesis in a pig model

Field: Medicine (Health Sciences)

Relevance. The frozen elephant trunk technique is recognized as a safe and effective method of surgical treatment for aneurysms and dissections of the thoracic aorta. The hybrid prostheses, available on the territory of the Russian Federation, are foreign-made, characterized by a high price, and, accordingly, unpopular. Due to unavailability of domestic hybrid prostheses in the home market, the development of domestic prosthesis is the key point to further progress in aortic surgery in the Russian Federation. Aim . The aim of the study was to evaluate the implantation characteristics of prototype hybrid thoracic aorta prosthesis in the pig model and the transformation of the prosthesis in the postoperative period. Material and Methods . The hybrid prosthesis consists of two parts including the vascular part and a stent graft. The prosthesis is made of Dacron and Z-shaped nitinol wire stents. A Landrace pig aged six months with body weight of 120 kg underwent open reconstruction of the descending aorta through the left-sided lateral thoracotomy, under conditions of extracorporeal bypass with a roller pump from the left subclavian artery to the descending aorta. The animal was removed from the experiment after six months as planned. The macro- and microscopic evaluation of the removed implant was performed. Results . The technical success of implantation of hybrid stent graft prototype was confirmed. Macroscopy of the stent graft, removed after six months, demonstrated a complete coverage of the neointimal inner surface of the synthetic prosthesis. The lumen of the product was patent. Histological examination revealed the neointima presented as a structured connective tissue without signs of inflammation. The luminal surface was lined with a single layer of evenly spaced endotheliocytes. The thickness of the neointima in the vascular part was significantly greater than in the stent-graft part ( p = 0.0121). Conclusion. The study demonstrated the technical feasibility of implantation of the prototype hybrid prosthesis developed by Angioline Research LLC. The effectiveness of sealing impregnation was confirmed by the absence of active signs of bleeding during the perioperative and early postoperative stages. The prosthesis demonstrated satisfactory bio- and hemocompatibility.
Effects of benzoxazinoids on specialist and generalistDiabroticaspecies

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract Benzoxazinoids are constitutively produced secondary metabolites in maize that protect the plant from the negative effects of insect herbivores. In this study, we determined the effects of benzoxazinoids on the maize specialist Diabrotica virgifera virgifera and a congeneric generalist Diabrotica undecimpunctata howardi . We compared the survival, growth and development of larvae fed on maize line 428G, which is defective in benzoxazinoid biosynthesis, and H88, the wild‐type parental line of 428G with normal benzoxazinoid production. There were no negative effects of benzoxazinoids on survival, growth and development of either western corn rootworm or southern corn rootworm. Western corn rootworms gained more weight than southern corn rootworms when feeding on benzoxazinoid‐containing corn. Our results support the hypothesis that specialist and generalist insects respond distinctly to benzoxazinoids.
Identification of the cooling system of a large business center

Field: Engineering (Physical Sciences)

This paper deals with the development of a control oriented model for a real cooling station serving a large business/commercial area with about 65,000 square meters of spaces and 3,000 permanent workplaces. The model is derived by focusing on one of the subsystems at a time, eventually simulating the physical closed-loop present in the plant. Since first principle equations would be impractical in view of the dimension and uncertainty of the system, the model largely relies on black-box relations estimated from the available measurements. The final model can be used for the design of an optimization-based model predictive control algorithm.
A compact multi-mode CORDIC with Global-Shifting-Sum (GSS) method

Field: Computer Science (Physical Sciences)

Coordinate Rotational Digital Computer (CORDIC) has been widely used as an iterative algorithm for performing rotations in many digital signal processing (DSP) applications. The CORDIC algorithm is divided into two modes, which are the rotation and vectoring modes. The conventional hardware architecture of CORDIC algorithm has two problems. First, though the computations of both modes are very similar, two separate modules are used in separate hardware architecture. Second, after computations of the whole iterations, an extra scaling operation to make a normalized output has been another computational burden. In this paper, we present a compact multi-mode CORDIC architecture, where both of the rotation and vectoring modes can be performed using a shared hardware architecture. In addition, Global-Shifting-Sum (GSS) approach which uses one adder and one barrel shifter is also proposed to efficiently eliminate the scaling operation of CORDIC. The proposed multi-mode GSS CORDIC is implemented as the iterative cross-folded architecture to minimize the area of CORDIC. The experimental results with 65nm CMOS process show 42% area reduction compared to the conventional two separate hardware architectures of CORDIC with minor degradation in accuracy.
Reconsidering the Equids from the Early Pleistocene Fauna of Apollonia 1 (Mygdonia Basin, Greece)

Field: Earth and Planetary Sciences (Physical Sciences)

The remains of equids are abundant in the Early Pleistocene faunas of Greece. “Apollonia-1” is one of the richest localities from the latest Villafranchian, providing eight skulls, mandibular remains and plenty of postcranial material during several field campaigns. This study focuses mainly on the skulls, mandibular remains and metapodials from the old and new collection described in detail. The specimens are compared with equids from several Greek and European fossiliferous localities dating from the late Villafranchian to the middle Galerian. The systematic position of Equus apolloniensis is also discussed. Based on its basicranial proportions, E. apolloniensis is considered a true Equus. A second species has also been identified recently, here referred to as Equus sp.; it is poorly represented, and it is even larger and more robust than E. apolloniensis based on a single metacarpal and third phalanges. The presence of two equid species in Apollonia 1 validates its Epivillafranchian (=latest Villafranchian) age.
Thermophysical modeling of raw glaze liquidus temperature and viscosity

Field: Materials Science (Physical Sciences)

Abstract Raw glazes, which do not contain pre‐melted glass frits, are widely used due to their low cost. The natural variability of the mineral compositions used in raw glazes affects their viscosity during firing. Molten glaze viscosity plays an important role in determining the final surface quality; therefore, it is important to determine how raw glaze composition and firing conditions affect viscosity. Thermophysical modeling provides a way to evaluate the liquidus temperature and viscosity of molten glazes as a function of composition and oxygen activity. Equilibrium phase volume fraction and composition of 242 raw glaze recipes were evaluated under oxidizing and reducing conditions. Undissolved or precipitation of solid phases explains the secondary flux transition from anti‐fluxing to fluxing near the liquidus temperature. The liquidus temperature and viscosity of iron glazes decrease as a function of increasing iron content under a reducing atmosphere. The empirical probability distribution of molten glaze viscosity follows a lognormal distribution, with lead glazes having significantly lower viscosity compared with glazes without lead. The peak firing temperature viscosity of lead‐free glazes is near the working point of glass. Multiple linear regression analysis shows that the peak firing temperature viscosity and liquidus temperature significantly predict the viscosity factor.
Cloning Of A Β-Glucosidase Gene (Bgl1) From Traditional Starter Yeast Saccharomycopsis Fibuligera Bmq 908 And Expression In Pichia Pastoris

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

β-Glucosidase is an important enzyme for production of ethanol from lignocellulose. With hydrolytic activity on cellooligosaccharides, especially cellobiose, β-glucosidase removes product inhibitory effect on cellulases and forms fermentable sugars. In this study, β-glucosidase encoding gene (BGL1) from traditional starter yeast Saccharomycosis fibuligera BMQ908 was cloned and expressed in Pichia pastoris. BGL1 of S. fibuligera BMQ 908 shared 98% nucleotide homology with the closest GenBank sequence (M22475) but identity in amino-acid sequences of catalytic domains. Recombinant plasmid pPICZαA/BGL1 containing the sequence encoding BGL1 mature protein and α-factor secretion signal was constructed and transformed into methylotrophic yeast P. pastoris by electroporation. The recombinant strain produced single extracellular protein with molecular weight of 120 kDa and cellobiase activity of 60 IU/ml. The optimum pH of the recombinant β-glucosidase was 5.0 and the optimum temperature was 50°C.
Time-domain auditory processing of speech

Field: Neuroscience (Life Sciences)

Speech patterns develop over time. Temporal phenomena extend from the very short to the very long: timbre, pitch and segregation cues, segmental, prosodic and rhetoric patterns, memory, learning, development and evolution. This paper focuses on the lower end of the scale, where time-domain descriptions merge with spectral descriptions. Temporal cues are used by the listener to organize the auditory scene, parse acoustic information, and assign the relevant fragments to one speaker among several. Cues include interaural delays (that vary according to source position), periodicity (of voiced speech), and envelope modulations such as onsets. Temporal cues may determine pitch (intonation) and timbre (of vowels or consonants), for which it is also common to find accounts based on spectral cues. Frequency and time are closely linked. With a frequency-selective cochlea the ear is equipped to analyze spectral patterns, but from physiology we know that their temporal counterpart is also present in the auditory nerve. Synchrony to the acoustic signal degrades as patterns proceed towards the cortex, but accurate temporal information is available for processing at several levels and there is abundant evidence for neural &amp;quot;circuitry &amp;quot; specialized for time. Models that explain pitch on the basis of interval statistics between nerve firings are currently popular (although
Effect of Cd sup 2+ CN lipid composition of thylakoid membranes CF wheat chloroplasts

Field: Agricultural and Biological Sciences (Life Sciences)

Cadmium application in wheat plants decreased thylakoid total lipids, total glycolipids, total phospholipids and total neutral lipids by 22, 23, 12 and 25% respectively. MGDG and DGDG were the major glycolipids and their level decreased by 32 and 27%, respectively under cadmium treatment. Sulpholipids were also decreased by 27%. Cadmium application also decreased the concentration of phosphatidyl glycerol (PG) and phosphatidyl choline (PC) to the extent of about 57 and 31%, respectively. Phosphatidic acid, which could not be detected under control, appeared in cadmium treated leaves. Triglycerides, the major constituents of neutral lipids, were decreased by 68%. However, free fatty acid content increased by about 19% under cadmium treatment. These results indicate that cadmium treatment affects the architecture of thylakoid membranes which in turn may adversely affect the light reactions of photosynthesis.