jimnoneill/paper-to-field-training huggingface dataset:
Ecological Status Report: results from the CPR Survey 2004/2005.

Field: Agricultural and Biological Sciences (Life Sciences)

Using a number of ecological indices, this report summarises unusual species found, large phytoplankton blooms, changes in community structure and trends in hydrobiological indicators from regions in the North Atlantic (with an emphasis on the North Sea). In the majority of cases the term unuasual or large in referring to phytoplankton blooms refers to population increases greater than four standard deviations above the species recorded baseline mean (baseline mean: 1980-2003). Notable blooms that are geographically lareg refer to patch sizes greater then 100 km in diameter. The primary regional assessment area used to monitor changes in community structure, biomass and phenological changes is the central North Sea. Most data analysis has been performed to highlight the year 2004 in relation to the long-term dataset. 2005 sample data is presented but has not yet undergone quality checks. Annual abundance estimates were calculated for each CPR box when eight or more months were sampled, no annual estimate of abundance was calculated. Sea surface temperature was used as an indicator of ocean climate and climate change.
Atypical Opioid Mechanisms of Control of Injury-Induced Cutaneous Pain by Delta Receptors

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Abstract : Severe pain due to war-related injuries is difficult to treat, and current opioids (i.e. mu opioid receptor agonists such as morphine) cause unacceptable side effects including addiction. Injuries suffered most frequently by active military personnel include traumatic brain injury, nerve trauma, skin incision, and burn injury, and all these injuries are associated with acute cutaneous pain and/or mechanical allodynia/hypersensitivity. The goals of our research are to evaluate analgesics acting on delta opioid receptors (DORs) in animal models relevant to todays battlefield experience (Specific Aim 2), and elucidate the mechanisms by which DOR agonists, administered in skin and acting on mechanosensory dorsal root ganglia neurons, relieve pain (Specific Aim 1). We have determined the analgesic effect of two DOR agonists, deltorphin II and SNC80. We show that these compounds significantly elevate mechanical pain threshold, indicating their acute antinociceptive action. Furthermore, we found that in two models of injuries, namely skin incision and nerve trauma, a single injection of deltorphin II eliminates the mechanical hyper sensitivity caused by injury. We have also initiated studies aiming at identifying the peripheral sensory neurons that express DOR, a first step towards understanding the analgesic mechanism of action of DOR agonists. We are currently extending these findings by performing the other experiments described in our original proposal, without significant change in our plans and strategy. Importantly, our promising results support our hypothesis that DOR agonists, acting in the skin, represents an effective therapeutic strategy for blocking severe pain associated with injuries that can be suffered on the battlefield.
Determination of the AuCu Superlattice Formation Region in Gold-Copper-Silver Ternary System

Field: Materials Science (Physical Sciences)

The composition and temperature range of the AuCu-type superlattice formation in the Au-Cu-Ag ternary system was determined by X-ray powder diffraction. Four distinguishable phase transformations were detected, i.e., 1) α (disordered FCC phase) → AuCu I, 2) α → AuCu II, 3) α → α 1 (Cu-rich FCC phase) + α 2 (Ag-rich FCC phase), and 4) α → AuCu3. The stable temperature range of the AuCu I-type superlattice was restricted to a lower temperature range by adding silver to stoichiometric and off-stoichiometric Au-Cu alloys. Depending on the increase in silver content, the co-existing region of the AuCu II-type superlattice and the silver-rich α 2 phase extended to the lower temperature and over a wide composition range.
FIGURE 2 in A large coelacanth, †Whiteia giganteus sp. nov., from the Triassic of Texas, USA, establishes a Pangean radiation of early Mesozoic actinistians

Field: Earth and Planetary Sciences (Physical Sciences)

FIGURE 2. Anatomy of †Whiteia giganteus gen. et sp. nov. YPM VP 3928 in left lateral view, showing detail of rostrum.
Coronary artery disease and coalworkers' pneumoconiosis.

Field: Medicine (Health Sciences)

compression.Might I suggest to these gentlemen that they give electrical stimulation a trial-it does not cause bleeding and the neat "electronic" foam polyethylene gaiters6 (Donns Surgical Ltd) are much easier to apply and remove than a stocking.Moreover, electrical stimulation has given me ten years in general surgery without a serious pulmonary embolus, even when the patient has cancer.To Mr Clayton may I say that the gaiter may not have a good name in Leeds, where it was tried in the orthopaedic department for hip replacements.It was not satisfactorybut no other method is either with this operation.
A Strategy for Building Public Service Motivation Research Internationally

Field: Social Sciences (Social Sciences)

As public service motivation research grows qualitatively and quantitatively, some scholars question its appropriateness for international applications. This essay sets out a strategy of convergence for international research and measurement approaches. Studies that assess commonalities in public service motivation content internationally are analyzed in order to develop a broader conceptual and more operational definition as well as consequently a more universal public service motivation construct. Public service motives, according to this review, are based on self‐sacrifice and fall into three categories: instrumental, value‐based, and identification. The dimensions of the public service motivation construct are refined along the lines of attraction to public participation, commitment to public values, compassion, and self‐sacrifice. Researchers are urged to include all of its dimensions within their empirical studies to advance contemporary public service motivation studies.
Advances in Region-of-Interest Video and Image Processing

Field: Computer Science (Physical Sciences)

The advent of cheaper and more powerful devices with the ability to play, create, and transmit video content has led to a dramatic increase in the multimedia content distribution on both wireline and wireless networks. Also, the reduction of cost of digital video cameras along with the development of user-generated video sites (e.g., iTunes™, YouTube™) stimulated a new user-generated video content sector and made unprecedented demands for high-quality and low-delay video communication. The Region-of-Interest (ROI) is a desirable feature in many future scalable video coding applications, such as mobile device applications, which have to be adapted to be displayed on a relatively small screen; thus, a mobile device user may wish to extract and track only a predefined ROI within the displayed video. At the same time, other users having a larger mobile device screen may wish to extract other ROIs to receive higher video stream resolution. Therefore, to fulfill these requirements, it would be beneficial to simultaneously transmit or store a video stream in a variety of ROIs, as well to enable efficiently tracking of the predefined Region-of-Interest. This chapter presents recent advances in Region-of-Interest video and image processing techniques for multimedia applications, while making a special emphasis on a scalable extension of the H.264/AVC standard. The detailed observations and conclusions, which are presented in this chapter, are supported by authors’ personal experience in this field, thereby presenting a variety of experimental results.
WaveLINE-003: Phase 2/3 trial of zilovertamab vedotin plus standard of care in relapsed/refractory diffuse large B-cell lymphoma.

Field: Medicine (Health Sciences)

7005 Background: Outcomes for patients relapsed/refractory (R/R) diffuse large B cell lymphoma (DLBCL) remain poor. Zilovertamab vedotin (ZV) is a novel ROR1-targeting antibody-drug conjugate that has shown promising efficacy in patients with DLBCL. Here we present results of the dose confirmation part of the waveLINE-003 (NCT05139017) trial evaluating ZV plus rituximab and gemcitabine-oxaliplatin (R-GemOx) in pts with R/R DLBCL. Methods: The phase2/3 trialwaveLINE-003 enrolled adult participants (pts) with confirmed R/R DLBCL after ≥1 lines of therapy (LOT) who were ineligible for chimeric antigen receptor T-cell therapy (CAR-T), autologous stem-cell transplant (ASCT), or failed such therapies (cohort A). In the dose confirmation phase, eligible pts received ZV (1.5, 1.75, or 2.0 mg/kg) plus R-GemOx Q3W for ≥6 cycles. Primary endpoints were safety and recommended phase 2 dose (RP2D). Secondary endpoints were objective response rate (ORR) and duration of response (DOR) per Lugano 2014 response criteria by central review, and overall survival. Results: At data cut-off date (August 1, 2024),40 pts had been enrolled in cohort A to receive R-GemOx plus ZV 1.5 mg/kg (n=17), 1.75 mg/kg (n=16), or 2.0 mg/kg (n=7); 22 (55%) were ≥65 years old, and 8 (20%) relapsed >12 mo. Median number of prior LOTs was 2.0 with 7 (18%) pts receiving prior CAR-T, and 7 (18%) receiving prior ASCT. Median follow-up was 9.8 months (mo). Seven DLTs (1 for ZV [1.5 mg/kg], 2 for ZV [1.75 mg/kg], and 4 for ZV [2.0 mg/kg]) were reported. Treatment-related adverse events (AE) were reported in 39 (98%) pts; the most common being diarrhea (n=18 [45%]), nausea (n=15 [38%]), anemia (n=11 [28%]), and platelet count decrease (n=11 [28%]). Grade ≥3 treatment-related AEs were reported in 26 (65%) pts, the most common being neutropenia (n=9 [23%]), neutrophil count decreased (n=9 [23%]), platelet count decreased (n=9 [23%]), and anemia (n=8 [20%]). Two pts discontinued due to AE (sepsis and respiratory failure, both treatment-related), and 1 pt died due to sepsis (treatment related), all in the 2.0 mg/kg dose cohort. The RP2D was determined to be 1.75 mg/kg. ORR was 27% (3 CR, 1 PR [ZV 1.5 mg/kg]), 56% (8 CR, 1 PR [ZV 1.75 mg/kg]), and 57% (3 CR, 1 PR [ZV 2.0 mg/kg]), with median DOR of 14.4 mo, 8.7 mo and not reached (NR), respectively. Median overall survival was 11.5 mo (ZV 1.5 mg/kg), NR (ZV 1.75 mg/kg), and 7.4 mo (ZV 2.0 mg/kg), with 6-month OS rate of 70.0%, 78.8%, and 68.6%, respectively. Conclusions: Zilovertamab vedotin in combination with R-GemOx demonstrated promising efficacy and acceptable safety in R/R DLBCL at the RP2D of ZV of 1.75 mg/kg plus R-GemOx. The study is proceeding to the phase 3 portion randomizing patients to ZV-RGemOx versus RGemOx. Clinical trial information: NCT05139017 .
Synergia: An Advanced Object-Oriented Framework for Beam Dynamics Simulation

Field: Computer Science (Physical Sciences)

Synergia is a 3-D, parallel, particle-in-cell beam dynamics simulation toolkit. At the heart of the software development effort is the integration of two extant object-oriented accelerator modeling libraries— IMPACT written in Fortran 90 and mxyzptlk written in C++--so that they be steered by a third, more flexible human interface framework, written in Python. Recent efforts are focused on the refactoring of the IMPAT-Fortran 90 codes in order to expose more loosely coupled interfaces to the Python interface framework.
A Novel Kind of Knowledge Graph Construction Method for Intelligent Machine as a Service Modeling

Field: Computer Science (Physical Sciences)

With the development of Intelligent Machine as a Service (IMaaS), devices increasingly require personalization, intelligence, and service orientation, making resource modeling a key challenge. Knowledge graph (KG) technology, known for unifying heterogeneous data, has become an essential tool for modeling and analyzing manufacturing resources. On this basis, this study proposes a novel resource KG construction method for IMaaS. First, an E-R diagram is used to divide the constant and variable entities and set the constant attributes and the constant relationships. Then, the triplets are named, the value space is set, and the schema layer is constructed. Finally, the related information about devices is used to fill the data layer, and then, the knowledge graph is generated. Meanwhile, this study utilizes desktop FDM 3D printing devices as a case example for validation. The method proposed in this study can enhance the accuracy and maintainability of equipment resource management in the manufacturing sector, effectively promoting subsequent activities such as management, analysis, and decision-making.
Some nutritional requirements for enterotoxin production by Clostridium perfringens NCTC 8239 in the ligated intestinal loop of rabbit.

Field: Immunology and Microbiology (Life Sciences)

Both protein and carbohydrate were necessary for sporulation and enterotoxin production of Clostridium perfringens NCTC 8239 in the ligated intestine of the rabbit. The administration of 108 vegetative cells suspended in 2ml of skim milk was confirmed to induce positive reactions consistently. However, skim milk dialysate, which contained the same amount of protein as the 10% skim milk, had no effect. An addition of 10% lactose to the skim milk dialysate restored the effect. Proteose peptone (Difco), peptone for toxin production (Mikuni), meat extract (Wako) and purified casein (Merck) could replace the skim milk dialysate.In addition to lactose, raffinose and fructose were effective as carbon sources whereas galactose, sucrose and glucose were less effective. Enterotoxin was not produced in the ligated intestine when the vegetative cells were administered together with any one of these carbohydrate or protein sources alone.
Identification of Veterans Experiencing Symptoms of Mental Illness for the First Time after COVID-19 Diagnosis

Field: Medicine (Health Sciences)

There has been a general increase in psychiatric symptoms since the COVID-19 pandemic began. Literature that has been published since the start of the pandemic has indicated there is an increased risk of depression, insomnia, altered mental status, new-onset psychosis, neurocognitive syndrome, and anxiety. The military veteran population is at higher risk for psychiatric illness than the general population, and should be screened accordingly. This quality improvement project was developed in collaboration with the mental health clinic at urban medical center in the Midwest to identify new symptoms of mental illness after COVID-19 diagnosis utilizing the PDSA model and descriptive statistics. Veterans were screened via telephone for depression, anxiety, psychosis, PTSD, and dementia utilizing the PHQ-9, GAD- 7, PCCL, PCL-5 and TMMS. A 6% positivity rate for symptoms of new onset mental illness was found in a sample size of 50.
High Efficiency Operation of GaInAsP/InP Membrane Distributed-Reflector Laser on Si

Field: Engineering (Physical Sciences)

Record high power conversion efficiency operation of a GaInAsP/InP membrane distributed-reflector laser on silicon substrate was realized. In order to enhance the efficiency, both an improvement of external differential quantum efficiency and a reduction of differential resistance were achieved. As a result, an external differential quantum efficiency from the front facet of 36%, and a maximum power conversion efficiency of 14.6% were obtained for a device with a 40-$\mu \text{m}$ -long active region.
Promotion of Mefenamic Acid Nucleation by a Surfactant\nAdditive, Docusate Sodium

Field: Chemistry (Physical Sciences)

The\ninfluence of docusate sodium (DOSS) on the nucleation of mefenamic\nacid (MEF) has been studied in different dimethylacetamide (DMA)–water\nmixtures. A series of induction time experiments were conducted under\nmoderate supersaturations, varying the solvent composition and the\nconcentration of DOSS. In 40% DMA–60% water, the presence of\n0.1 and 0.2 mg/mL DOSS increased the nucleation rate. Evaluating the\nresults by the classical nucleation theory reveals that the pre-exponential\nfactor (<i>A</i>) increases by approximately 50% while the\ninterfacial energy is essentially uninfluenced. It is also found that\nthe crystal growth rate becomes higher in the presence of DOSS. It\nis thus hypothesized that transport and desolvation of MEF molecules\nare facilitated in the presence of DOSS. With increasing amount of\nDMA in the binary solvent mixture, the influence of DOSS appears to\ndecrease.
INTEGRATED COOLING SOLUTIONS FOR ELECTRIC VEHICLE BATTERY PACKS: A SIMULATION STUDY

Field: Energy (Physical Sciences)

The simulation study delves into the vital role of thermal management in battery systems, which is critical for battery longevity and efficiency in applications such as electric vehicles and renewable energy storage. The research highlights the significant impact of heat generation on overall battery health and performance under constant charging and discharging cycles. Thermal management, which is critical for minimizing temperature-related difficulties, tries to minimize overheating or severe cold, both of which are known to reduce efficiency and limit operational life. The study analyses the complicated relationship between battery performance and the addition of an air conditioning system using simulation tools such as ANSYS 2023 R2. The planned air-cooling system seeks to maintain an optimal battery temperature range of 20 to 50 °C, with battery cells anticipated to attain a temperature of 55 °C during operation. The goal is to evaluate the feasibility and long-term effectiveness of incorporating air conditioning systems to improve battery thermal performance and potentially extend operating life. This comprehensive technique ensures battery durability and adaptability in our ever-changing electric landscape.
Regularity of solutions to time-harmonic Maxwell's system with Hölder and various lower than Hölder continuous coefficients

Field: Mathematics (Physical Sciences)

The purpose of this paper is to establish a complete Schauder theory for the second-order linear elliptic equation and the time-harmonic Maxwell's system. We prove global Hölder regularity for the solutions to the time-harmonic anisotropic Maxwell's equations under Hölder continuous coefficients, raising the Hölder index to the interval (0,1)
The Accumulation of Zinc and Nickel in Irankoh Indigenous Plant Species on a Contaminated Land

Field: Environmental Science (Physical Sciences)

Abstract The accumulation of heavy metals by plants determines both the micronutrient content and the toxic metal content of our food. A field survey of higher terrestrial plants growing on a metalliferous site of the Iranian arid mountain in Isfahan was conducted to identify species accumulating exceptionally large concentrations of Zn and Ni in shoots and roots. Plant samples were collected from Irankoh areas near the Bama Pb and Zn mine. Sampling was carried out in Spring 2004 and analyzed for DTPA (Diethylene triamine pentaacetic acid) extractable Zn and Ni by atomic absorption spectrophotometry. Mean total and available Zn in the studied soils were 259.7 μgg−1 and 5.067 μgg−1, respectively. Soil total and available Ni were relatively low (58.9 μgg−1 and 0.143 μgg−1 respectively). Zinc concentrations were considerably high in shoots of Stachys inflate, Ebenus stellata, and Astragalus glaucanthus (556.88, 508.8, and 449.53 μgg−1, respectively). Nickel concentrations were markedly high in shoots of Teucrium polium, Alyssum bracteatum, and Ebenus stellata (13.21, 10.98, and 8.84 μgg−1, respectively). Zinc translocation factor (TF or shoot/root concentration ratio) was higher than Ni TF in most plant species. Zinc and Ni enrichment factors and shoot/root concentration ratios were also significantly high in Stachys inflate, Ebenus stellata, Astragalus glaucanthus Teucrium polium, Stipa barbata, Bromus tectorum, and Alyssum bracteatum. Results suggest that these plants could be good candidates for use in the revegetation and phytoremediation of Zn and Ni contaminated lands in arid regions. Keywords: Alyssum bracteatum Astragalus glaucanthus Ebenus stellata IranNiPhytoremediation Stachys inflate Teucrium polium Zn Notes * Equivalent calcium carbonate. a Means followed by the same letter are not significantly different (P < 0.05). a Means followed by the same letter are not significantly different (P < 0.05).
Consultation on establishing robust integrated national reporting systems for viral hepatitis

Field: Health Professions (Health Sciences)

for viral hepatitis 1 This report is extracted from the Summary report on the Consultation on establishing robust integrated national reporting systems for viral hepatitis, Casablanca, Morocco, 10-11 December 2018 (http://applications.emro.who.int/docs/IC_meet_rep_2019_22334_en.pdf?ua=1).
Institutional Quality and Income Inequality: Evidence from Post-Soviet Countries

Field: Economics, Econometrics and Finance (Social Sciences)

This paper focuses on identifying the relationship between institutional quality and income inequality in chosen post-Soviet countries during the period 2002–2017. Using panel analysis is found a nonmonotonic relationship between institutional quality and income inequality. Increasing institutional quality is associated with growing income inequality, but only to a certain extent; from a certain level, higher institutional quality leads to a reduction in income inequality. The growing institutional quality leads to a deepening of income inequality between the richest social class compared to the poorest and middle class. Role in this process plays a particular regulatory quality, which – as it seems – favors the upper 20%.
Updated Insights into Gut Bacterial Diversity in <i>Apis Mellifera</i> Populations from India

Field: Agricultural and Biological Sciences (Life Sciences)

The gut microbiota of Apis mellifera plays a crucial role in nutrition, immunity, and overall health. This study examines the cultivable and metagenomic diversity of gut bacteria in Indian A. mellifera forager and hive bees using cultivation techniques and 16S rRNA sequencing. Bacterial strains were isolated from foragers and hive bees, with ARDRA analysis identifying 51 and 34 unique isolates, respectively. Metagenomic sequencing revealed 22,756 OTUs spanning 18 bacterial phyla in hive bees and 10 in foragers. Proteobacteria, Firmicutes, Actinobacteria, and Bacteroidetes dominated the gut. Core microbiota analysis identified Snodgrasella alvi, Gilliamella apicola, Frischella perrara, Bifidobacterium asteroides, and Lactobacillus taxa, with notable absences in each group. Variations in microbial composition suggest ecological and functional distinctions between forager and hive bees. These findings enhance our understanding of honey bee gut microbiota and its implications for bee health and conservation.
Phase II trial of high‐dose dexamethasone for previously treated immunoglobulin light‐chain amyloidosis

Field: Medicine (Health Sciences)

Immunoglobulin light-chain amyloidosis (AL) is a rare disorder characterized by production of a monoclonal light chain. This insoluble light chain, or a fragment thereof, deposits in tissues as amyloid and results in disruption of organ function and, ultimately, in death. Although melphalan and prednisone are beneficial in approximately 30% of patients with the disease, many patients fail to respond, and the median survival with this disease remains < 2 years. There is a need for new agents for those patients who fail to respond to melphalan-based chemotherapy. A study was undertaken of high-dose dexamethasone in the treatment of 19 patients with AL because of reports of its benefits in previously untreated patients with amyloidosis and its known activity in the management of multiple myeloma, which has many characteristics in common with AL. In this cohort, 3 of 19 patients showed an objective organ response of the disease. The median survival of the entire group was 11.2 months. We conclude that high-dose dexamethasone therapy is of occasional benefit in patients previously treated for amyloidosis. Combining dexamethasone with other therapies may increase the response rate. Am. J. Hematol. 61:115–119, 1999. © 1999 Wiley-Liss, Inc.