jimnoneill/paper-to-field-training huggingface dataset:
RADIOSENSITIVITY IN DIFFERENT STAGES OF SPERMATOGENESIS IN DROSOPHILA MELANOGASTER

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

RADIOSENSITIVITY I N DROSOPHILA MELANOGASTER 22 1 spermatogenesis with more exactness, single males mated to at least 5 females in daily broods should be used.In order to elucidate some of the problems concerned with the differences between the time intervals indicated, the following questions were taken up for further investigation.1. Is the brood pattern independent of the age of the male and determined only by the stage of sperm at radiation? 2. Does the sensitivity pattern vary for different kinds of mutations, i.e. visibles, sex-linked lethals, 11-111 translocations, or is it the same?3. At what stage or stages in spermatogenesis does peak sensitivity occur?4. What is the interpretation of the sterile period? MATERIALS AND METHODSThe wild type males used in the present experiments are from a wild type Canton S stock, maintained in mass culture.The mutant stocks used in the various experiments described below are designated by the standard symbols in BRIDGES and BREHME (1944).-411 stocks and experimental cultures have been raised on the standard corn-meal -agar molassesyeast medium, seeded with live yeast.The sensitivity of mature sperm was determined after irradiation of 3 day old males with one 24 hour mating period.Brood patterns were obtained with 24 hour mating periods, usually after irradiation of 0-4 hour old males.The mating procedure used has been described by MOSSIGE (1956).The technical details varied in the four types of experiments and are briefly described below.A. The sex-linked recessive lethals were scored by the Muller-5 method (the M,-chromosome=scS B In-S w a sc').0 -4 hour old CS+ males were mated individually to 5 virgin M, females, for 4 days.The F, females from Days 1 and 4 were used for controls.Then on Day 4, the males were irradiated and mated to new virgin M, females.6 successive broods were obtained after the irradiation of the males.At least 40-50 flies in F, from each F, female, without wildetype males and with at least 10 M, males, was taken to indicate a lethal factor in the X-chromosome of the irradiated male.A further generation was tested when the number of flies was insufficient.B. 11-111 Translocations were studied after irradiating wild type males and mating these individually to 5 virgin cn bw; e females.Successive 24-hour broods were obtained for 15 days from males irradiated
Diagnosis of invasive amoebiasis: renaissance of the morphology era.

Field: Medicine (Health Sciences)

of cytokines such as transforming growth factor ,B is likely to be an epiphenonemon of the inflammatory process.Finally, we support the view of Cavallini et al that while calcification might contribute to the pathogenesis of chronic pancreatitis in its later stages, there is no well documented evidence fulfilling Koch's postulates that it is probably a significant aetiological factor in the disease.Hence, we also cannot support the hypothesis of the Marseilles school.2We consider that the disease known as 'chronic pancreatitis' is not a single pathological entity but rather a group of different aetiologies and pathogenetic processes sharing a few common morphological end points.3Within this overall group, we anticipate that a predisposition based upon an identifiable genetic abnormality is the likely primary aetiological factor responsible for at least a proportion of cases of chronic pancreatitis.Whether this defect occurs within the pathway of alcohol metabolism or is responsible for promoting an inappropriate cell mediated cytotoxic response to some pancreatic cellular antigen is presently unknown.Nevertheless, answers to such questions are vital if biologically appropriate treatment regimens for different aetiologically and pathogenetically distinct types of 'chronic pancreatitis' are to be developed and affected patients treated more rationally than at present.
Activity Study of Ciliary Neurotrophic Factor(CNTF)Mutant

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

To study still further the activity of CNTF mutant designed by computer molecular modling,the methods of dissociated cultures of chick dorsal root ganglion、TF-1 prolification and the normal mice'weight loss tests weve used.The results indicated that the mutant protein promoted the survival of dorsal root ganglion、induced TF-1 prolification and made the normal mice lose weight,decrease appetite and reduce fat index.The weight loss effect was dependant with its administration dosage,ED50 was 150.986μg/kg/d.To TF-1,the specific activity reached 2.0×106U/mg against international reference reagent.In a word,CNTF mutant had excel bioactivity.So it provided clues for its development and application.
Self-prescribing of noncontrolled substances among pharmacists

Field: Health Professions (Health Sciences)

Journal Article Self-prescribing of noncontrolled substances among pharmacists Get access Ebrahim A. Balbisi, Pharm.D., Ebrahim A. Balbisi, Pharm.D. Assistant Clinical Professors of Clinical Pharmacy Practice School of Pharmacy, St. John's University, Jamaica, NY Address correspondence to Dr. Balbisi at the School of Pharmacy, St. John's University, 8000 Utopia Parkway, Jamaica, NY 11439 (balbisie@stjohns.edu). Search for other works by this author on: Oxford Academic Google Scholar Emily M. Ambizas, Pharm.D. Emily M. Ambizas, Pharm.D. Assistant Clinical Professors of Clinical Pharmacy Practice School of Pharmacy, St. John's University, Jamaica, NY Search for other works by this author on: Oxford Academic Google Scholar American Journal of Health-System Pharmacy, Volume 62, Issue 23, 1 December 2005, Pages 2508–2511, https://doi.org/10.2146/ajhp050007 Published: 01 December 2005
Drain It Twice, Half the Price! Interval Partial Drainage of Pancreatic Cyst as a Bridge to Surgery

Field: Medicine (Health Sciences)

Introduction: Pancreatic cysts can complicate pancreatitis, and can generally be managed conservatively unless they become symptomatic, the cyst enlarges, or there is a complication such as infection, hemorrhage, obstruction, and potential rupture. Drainage is indicated in these cases. If malignancy is suspected or the cyst is simply too large, surgery is recommended. There are no guidelines for partial drainage of infected pancreatic cysts for symptom control as a bridge to surgery. Case: A 52-year-old female presented to the ED with left-sided abdominal pain associated with nausea and vomiting. She had pancreatitis 2 years prior, for which she was treated conservatively. An abdominal CT revealed a well-circumscribed 5.7x5.6 cm lesion in the pancreas body. An endoscopic ultrasound (EUS) with fine-needle aspiration (FNA) was performed. Approximately 80 cc of fluid was aspirated, with cyst collapse. Fluid cytology was consistent with a mucinous cystic neoplasm. The patient's symptoms improved after aspiration, but recurred a few days later. She presented to the ED with worsening abdominal pain, fever and leukocytosis concerning for an infected pancreatic cyst. Repeat CT scan showed new focal outpouching at the site of the cyst. EUS with FNA was repeated. A large cyst with internal debris was noted in the body of the pancreas. On aspiration, the fluid was thick and turbid. Complete aspiration was unsuccessful due to internal debris. Fluid cytology was consistent with an abscess. She was empirically treated with imipenem-cilastin. These interventions served as bridging treatments for an acute iatrogenic infection until she underwent a pancreatico-splenectomy 3 months later and her symptoms resolved. Discussion: Conservative management of pancreatic cysts is typically preferred and initially attempted. This ranges from a spectrum of observation to minimally invasive procedures for cyst drainage. Our patient's pancreatic cyst fulfilled 2 indications for surgical removal: large size and malignancy. After the first aspiration showed a cystic neoplasm, surgical removal would have been pursued. However, with symptom recurrence and concern for infection, repeat drainage was necessary, either percutaneously or via repeat EUS with FNA. The latter modality was chosen to minimize the risk of spreading malignant cells. Along with antibiotics, this was a successful bridge in treating a pancreatic cyst complication until surgery was feasible.Figure: CT scan showing initial cyst dimensions.Figure: CT scan showing cyst with outpouching after first drainage.
A New Theoretical Approach to Ancestry Estimation as Applied to Human Crania

Field: Social Sciences (Social Sciences)

Since Frank Livingstone proposed the idea that there are no races, only clines, in 1962, little has changed in the way that anthropologists study and, ultimately, estimate ancestry.The way in which we talk about the study of human variation may have changed--shifting away from "racial" labels and towards those of supposed ancestral origins--but the methods with which we label and analyze groups, however termed, has remained the same.In this paper, I suggest a new theoretical approach to ancestry estimation that does not rely on group labels using Howells Craniometric dataset as an example.In the suggested workflow, the data structure themselves into natural clusters, which I am referring to as Morphogroups, without the reliance of a group label.Each Morphogroup is explored for sub-groups and the process is repeated until no further distinctions can be made.At each level an individual is compared to the Morphogroup in a
Study on culture of hairy roots of Glycyrrhiza uralensis fisch

Field: Agricultural and Biological Sciences (Life Sciences)

Some factors that affected the hairy roots growth of Glycyrrhiza uralensis fisch and Glycyrrhiza inflata bat were studied,including the source of fermentation seed,the temperature,the rotate speed and the dissolved oxygen in medium.According to the parameter data of fermentation in 5L culture and 0.5L flask cultivation,the technology of 10L stirred bioreactor was established.The results showed that:using 1‰～3‰ inoculums size,25℃,40r/min and rotated speed 0.5vvm applied air,the growth rate of the 60 days hairy roots obtained from 10L stirred bioreactor was 55～60 no less than those cultured in flask.The glycyrrhizinic acid was detected in hairy roots of Glycyrrhiza uralensis fisch by HPLC whose content was 0.1% dry weight.
Niemann-Pick Disease Presented with Cystic Lung Involvement

Field: Medicine (Health Sciences)

A 44-year-old female patient presented with the complaints of dyspnea on exertion, cough, and sputum.It was learned from her medical history that she had dyspnea for the last 1 year, and it increased with exertion; the complaints of cough and sputum began 1 month ago.Her physical examination revealed inspiratory rales in bilateral middle-lower regions, and posterio-anterior chest radiography showed reticular and reticulonodular infiltrates in bilateral middle-lower regions (Figure 1).Based on these findings, we planned to examine the patient for interstitial pulmonary disease (IPD).It was learned that she had a history of Niemann-Pick disease during childhood.Bilateral diffuse groundglass opacites, interlobular septal thickening in bilateral bases, and bilateral cystic lesions were observed in high-resolution thoracic tomography (Figure 2).
Effect of Biogas Volume Flow Rate and Burner Temperature on Moisture Content of Organic Fertilizer in a Rotary Drying Process

Field: Chemical Engineering (Physical Sciences)

Different factors can influence the moisture content of product in an organic fertilizer drying process. In this study, biogas volume flow rate and burner temperature were systematically studied in an effort to ascertain their effect on the moisture content of organic fertilizer grain that had been subjected to rotary drum indirect heating procedures. It was found that these two factors did major effect on the moisture content of organic fertilizer in a rotary drum drying process. Additionally, it was also discovered that acceptable organic fertilizer moisture content occurred when the rotary drum drier utilized both the biogas volume flow rate of 0.058 m 3 /min. in combination with the drying temperature of 500°C while the percentage of biogas blower and burner operation were reduced by 22.67 % and 9.1%, respectively.
THE EFFECT OF GIVING EXERCISE THERAPY WITH THE MCKENZIE METHOD IN THE ELDERLY TO REDUCE THE PAIN OF HERNIA NUCLEUS PULPOSUS (HNP)

Field: Health Professions (Health Sciences)

Background : Hernia Nucleus Pulposus (HNP) is a state when the nucleus pulposus go out stand out then push to direction canal spinalis through annulus torn fibrosus. HNP often occur on area lumbar 4 - 2 lumbar 5 and lumbar 5 - sacrum 1. Pain in HNP due to by pathological processes in the column vertebral on discus intervertebral. By because that, from a number of the research that we get, giving therapy McKenzie workout effective in reduce pain Hernia Nucleus Pulposus (HNP). Research Objective: To find out influence give therapy McKenzie's workout against Hernia Nucleus Pulposus Condition. Methodology : Overview systematic from three related articles with give therapy McKenzie training on Hernia Nucleus Pulposus Condition. Results : Therapy practice with McKenzie method can give significant effect to reduce painful on Hernia Nucleus Pulposus Condition. Conclusion : Giving therapy practice with McKenzie method is able give influence reduce pain due to a herniated nucleus pulposus .
The Islamization of Southeast Asia

Field: Arts and Humanities (Social Sciences)

In Southeast Asian historiography, it is widely accepted that the history of the region is generally divided into the Indianized Southeast Asian and the Islamized Southeast Asian periods before the advent of the colonial era. The spread of Islam to insular Southeast Asia began around the late thirteenth and the early fourteenth centuries and signified the beginning of the decline of the Hindu cultural influence in the region. This chapter traces the indigenous socio-political and cultural landscape in the Malay world prior to the penetration of the Hindu culture, as well as the origins and acculturation processes of the Hindu and Islamic cultural influences in the region. SOCIO-POLITICAL AND CULTURAL LANDSCAPE IN INSULAR SOUTHEAST ASIA PRIOR TO THE FOURTEENTH CENTURY Shamanism Insular Southeast Asia is also generally known as the Malay world which, in the geographical context, includes “an area stretching from Sumatra in the west to the Spice Islands in the east, and from the island of Java in the south to the plains of Kampuchea in the Indo-Chinese Peninsula in the north” (Osman 2000, p. xxvi). In the cultural context, the Malay world refers to the early archipelago peoples who spoke Austronesian languages related to early Malay. They had come south from the mainland either by land, down the Malay Peninsula, or by sea to Taiwan and to the Malay Archipelago, some then crossing to the Indo-China mainland and others to the Malay Peninsula, and yet others across the Indian Ocean to Madagascar. (Wang Gungwu 2003, p. 13.) For the purpose of this study, a narrower geographical and cultural sense of the Malay world is adopted. Geographically, insular Southeast Asia or maritime Southeast Asia refers to the Malay cultural and linguistic sphere of influence, covering the archipelago of modern-day Indonesia, Malaysia, Singapore, the southern-most part of Thailand, the Philippines, Brunei, East Timor and some areas of New Guinea. Most of the languages spoken in the region are part of the Malayo-Polynesian family, including Tagalog, widely spoken in the Philippines, Javanese spoken in Java, and of course Malay, spoken in Malaysia, Singapore, Brunei and Indonesia. In this context, it covers the nucleus or core geographical and cultural boundaries of the Malay world.
Effect of Orientation and Strain Rate on Crush Strength of Cellulose Fiberboard Assemblies

Field: Engineering (Physical Sciences)

Cane fiberboard is widely used as the impact absorption and thermal insulation material in overpacks for radioactive materials packages. The study described here investigated the properties of cane fiberboard assemblies under conditions important to radioactive materials packaging applications. Tests were performed for loading perpendicular and parallel to the planes of the fiberboard sheets for both slow and impact strain rates. Specimens loaded parallel to the plane of the fiberboard typically fail by buckling and consequently are less stiff than those loaded perpendicular to the plane of the fiberboard sheets. Specimens subjected to impact loading appear stiffer than those tested at slow strain rates.
Incidence of aspergillus flavus in stored dried cassava products and its association with aflatoxin production

Field: Agricultural and Biological Sciences (Life Sciences)

Udaga is derivative of cassava products traditionally produced by farmers through peeling, fermentation and direct or indirect sun-drying of fermented cassava roots and widely consumed in Tanzania. The study was conducted in Lushoto, Rorya and Ukerewe districts in Tanzania based on diverse processing and storage methods between October and November 2012. Households (120) were interviewed on cassava processing and storage practices. Samples of dried cassava products were also obtained from interviewed households for moisture content, pH, microbial growth and aflatoxin content analysis. The factors that impact on mould and aflatoxin contamination of these products were established using regression analysis. Cassava products contained mean moisture content of 13.9%, pH 5.5 and aflatoxin ≥ 4 ppb in 8 samples. Mould incidence were Rhizopus spp. (59.17%), Cladosporium spp. (51.67%), Penicillium spp. (38.33%), Fusarium spp. (36.67%) Aspergillus spp. (20%) and Mucor spp. (4.17%). Aspergillus flavus was the most aflatoxin producing fungus isolated and occurred on 16.7% of all samples. Surface drying of cassava root pieces on bare ground rock surface, polypropylene sheet, rusty iron corrugated sheet roof and spread under roof (indirect sun drying) were some factors which were related to aflatoxin contamination. Other factors were fermentation of cassava products on rock surface, in polypropylene bags, heap under roof, heap on floor and cover with polypropylene bags/sheet, banana leaves, cassava peels and tree leaves. Storage practice positively significant correlated with aflatoxin contamination where cassava products were heaped under roof and stored in polypropylene bags.
“We call it put him away”

Field: Arts and Humanities (Social Sciences)

An ethnographic approach for documenting the funerary nature of museum objects is offered to complement existing practices for documenting collections under Native American Graves Protection and Repatriation Act. This approach draws on the Delaware Tribe’s work to identify funerary objects affiliated with the Delaware, which indicated that a cemetery, and not simply the graves within it, met the Native American Graves Protection and Repatriation Act definition for a burial site. This approach also revealed that a funerary object would be all the items that were found in association with human remains and/or were recovered from the fill and surface of each individual grave. Using such an approach requires ongoing consultation and engagement with potentially affiliated tribes during the documentation process and will likely result in producing alternative perspectives for documenting collections. Although a more time-intensive approach, it is one that holds greater potential for interpreting the mortuary intent of curated objects.
Litigating Together: Social, Moral, and Legal Obligations

Field: Social Sciences (Social Sciences)

In a post-Class Action Fairness Act world, the modern mass-tort class action is disappearing. Indeed, multi-district litigation and private aggregation through contracts with plaintiffs’ law firms are the new mass-tort frontier. But something’s amiss with this “nonclass aggregation.” These new procedures involve a fundamentally different dynamic than class actions: plaintiffs have names, faces, and something deeply personal at stake. Their claims are independently economically viable, which gives them autonomy expectations about being able to control the course of their litigation. Yet, they participate in a familiar, collective effort to establish the defendant’s liability. They litigate from both a personal and a collective standpoint. Current scholarship overlooks this inter-personal dimension. It focuses instead on either touting the virtues of individual autonomy or streamlining mass litigation to maximize social welfare. Both approaches fail to solve the unique problems caused by these personal dimensions: temptations for plaintiffs to hold out and thus derail settlements demanding near unanimity, outliers who remain disengaged from the group but free-ride off of its efforts, and subgroups within the litigation whose members compete for resources and litigation dominance to the group’s detriment. Accordingly, this Article has two principal objectives: one diagnostic, one prescriptive. The diagnosis is this: current procedures for handling nonclass aggregation miss the mark. Process isn’t just an exercise in autonomy or a handy crutch for enforcing substantive laws. Procedures can serve as a means for bringing plaintiffs together, plugging their individual stories into a collective narrative, making sense of that narrative as a community, reasoning together about the right thing to do, and pursuing that end collectively. Thus, the prescription is litigating together.
Right ventricular to pulmonary artery coupling credicts poor outcomes after interatrial shunting in heart failure

Field: Medicine (Health Sciences)

Abstract Background Left atrial decompression is under investigation for heart failure (HF) with the potential to improve symptoms and potentially clinical outcomes. However, heterogeneous outcomes have been observed in randomized controlled studies. Purpose This study aimed to explore whether right ventricular (RV) -pulmonary artery (PA) coupling, as assessed from the tricuspid annular plane systolic excursion (TAPSE) /systolic PA pressure ratio, can be useful in predicting outcomes after implantation of the interatrial shunting device. Methods A total of 106 HF patients, n=62 with reduced ejection fraction (HFrEF), n=44 with preserved ejection fraction (HFpEF), were prospectively enrolled in the PRELIEVE registry with the Atrial Flow Regulator (AFR) implantation. Serious adverse events included cardiovascular mortality and HF worsening (W). Results Serious adverse events (SAEs) occurred in a total of 19 (18%) patients. There were no differences in baseline comorbidities, KCCQ scores, the 6-minute walking distance between patients with and without SAEs (Table). Patients with SAEs showed higher systolic pulmonary arterial pressure, NT-proBNP, serum creatinine and lower TAPSE/PASP ratio. Incidence of SAEs was higher in patients within the first TAPSE/PASP vs the third tertile (59% vs 12%, p=0.026), respectively. A TAPSE/PASP of &lt;0.55 was identified to bear the most optimal sensitivity to predict the event (AUC=0.683, CI95% (0.533-0.833). Conclusion The reduced TAPSE/PASP ratio was associated with higher rates of serious adverse events in patients with heart failure undergoing controlled inter-atrial shunting. The hypothesis generating finding that reduced RV-PA coupling may identify potential clinical non-responders to left atrial decompression should be further prospectively validated.