jimnoneill/paper-to-field-training huggingface dataset:
Plagiochila cobana Steph., Sp. Hepat.

Field: Agricultural and Biological Sciences (Life Sciences)

Plagiochila cobana Steph., Sp. Hepat. 6: 138. 1918, syn. nov. Holotypus: ECUADOR. Pro v. Morona Santiago: Gualaquiza, Rosario, s.d., Allioni s.n. [Bryo. Levier 6490] (G [G00064144]!). = Plagiochila rutilans Lindenb. Notes. – Plagiochila rutilans is a common neotropical species that is distinguished by horizontally spreading, narrowly oblong-rectangular leaves with a shortly toothed apex, nonampliate ventral bases and subisodiametrical cells (HEINRICHS et al., 2001). Plagiochila cobana is identical to P. rutilans and a synonym.
A review of key characteristics that determine the efficacy of OHS instruments

Field: Social Sciences (Social Sciences)

Codes of practice and guidance material fulfil important roles in Australia and New Zealand under their respective regulatory regimes. The former provide greater certainty about what constitutes compliance and the latter provide broader advice. Yet notwithstanding their centrality to the success of OHS regulation, these mechanisms have been subject to very little empirical scrutiny. The principal aim of this report was to review key characteristics that determine the efficacy of OHS codes of practice and guidance materials and, in so doing, to fill some gaps in the knowledge base about them. The report is underpinned by a review of the literature relating to codes and guidance materials (both regulator and industry developed), in Australia, New Zealand and internationally, in the area of OHS and other areas of regulation. This review is complemented by detailed interviews and questionnaires administered to 54 respondents, drawn from OHS regulators, industry, unions, OHS and other specialists in seven countries (Australia, New Zealand, the United Kingdom, Canada, The Netherlands, Denmark and Finland). The review is also informed by an online survey of 22 users of codes and guidance materials (in Australia and New Zealand).
ZNF350 promoter methylation accelerates colon cancer cell migration

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Diversification of transcriptomic and epigenomic states may occur during the expansion of colorectal cancers. Certain cancer cells lose their epithelial characters and gain mesenchymal properties, known as epithelial-mesenchymal transition (EMT), and they aggressively migrate into the non-tumorigenic extracellular matrix. In this study, we isolated a subpopulation with accelerated baseline motility (MG cells) and an immotile one (non-MG cells) from a colon cancer cell line (HCT116). Gene expression signatures of the MG cells indicated that this subpopulation was likely an EMT hybrid. The MG cells substantially lost their migratory properties after treatment with a methyltransferase inhibitor, 5-azacytidine, suggesting a role of DNA methylation in this process. Global transcriptome assays of both types of cells with or without 5-azacytidine treatment identified 640 genes, whose expression might be methylation-dependently down-regulated in the MG cells. Global methylation analysis revealed that 35 out of the 640 genes were hyper-methylated in the MG cells. Among them, we focused on the anti-oncogene ZNF350, which encodes a zinc-finger and BRCA1-interacting protein. Notably, ZNF350 knockdown accelerated migration of the non-MG cells, while overexpression of ZNF350 in the MG cells significantly impaired their migration. Finally, pyrosequence analysis together with dual luciferase assays of serially truncated fragments of the ZNF350 promoter (-268 to +49 bp) indicated that three hyper-methylated sites were possibly responsible for the basal promoter activity of ZNF350. Taken together, our results suggest that hyper-methylation of the ZNF350 proximal promoter may be one of the crucial determinants for acquiring increased migratory capabilities in colon cancer cells.
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Approaches exploiting extremes of the trait distribution may reveal novel loci for common traits, but it is unknown whether such loci are generalizable to the general population. In a genome-wide search for loci associated with upper vs. lower 5th percentiles of body mass index, height and waist-hip ratio, as well as clinical classes of obesity including up to 263,407 European individuals, we identified four new loci (IGFBP4, H6PD, RSRC1, PPP2R2A) influencing height detected in the tails and seven new loci (HNF4G, RPTOR, GNAT2, MRPS33P4, ADCY9, HS6ST3, ZZZ3) for clinical classes of obesity. Further, we show that there is large overlap in terms of genetic structure and distribution of variants between traits based on extremes and the general population and little etiologic heterogeneity between obesity subgroups.
Female infertility due to abnormal autoimmunity: frequently overlooked and greatly underappreciated. Part I

Field: Medicine (Health Sciences)

When the impact of abnormal autoimmune function on female fertility is objectively examined, an unexpectedly large contribution is (auto)immune related. This may be surprising since many authorities have been dismissive of (auto)immune-associated infertility. In this article, we therefore summarize the link between abnormal autoimmune function and female infertility, based on literature searches. Abnormal autoimmune function affects female fertility at numerous levels of the reproductive process. As with autoimmune conditions in general, abnormal autoimmune function affecting fertility is often difficult to diagnose since it frequently presents subclinically, without overt clinical symptoms. It also demonstrates other characteristics of abnormal autoimmunity, such as familial occurrence and genetic predisposition, environmental cofactors contributing to phenotypic expression of genetic risk and cyclicity of occurrence, often characterized by gestational exacerbation patterns. Proven treatments for autoimmune-associated infertility have not been established to date. This fact should, however, not preclude efforts to reach correct diagnoses, since only accurate diagnoses can lead to appropriately conducted clinical trials.
Developing Education Through Value Internalization Of Hapolas Tradition In North Maluku

Field: Social Sciences (Social Sciences)

This study aims to analyze value internalization as an effort to develop education in North Maluku through Hapolas tradition. This is a qualitative research using a descriptive approach which is intended to explore and clarify the phenomenon of Hapolas in North Maluku province, especially South Halmahera regency, by describing a number of variables related to this problem. The research phenomenon is the effort of society to develop education through togetherness, kinship, cohesiveness, and cooperation, according to the philosophy of Hapolas tradition. The phenomenon is then implemented in social life so it is always sustainable and still implemented by every generation in the future. This research is not intended to test a particular hypothesis, but only describes the phenomenon as mentioned above, this is in line with the approach chosen by the author is qualitative where the author is not limited by a certain measuring instrument. Research data was collected through observation techniques, in-depth interviews, and documentation techniques. The data were analyzed using continuous interactive qualitative analysis technique. This research finding that developing more advanced education in North Maluku Province especially in South Halmahera regency is to internalize the values of togetherness, kinship, cohesiveness, and cooperation, as conceived in Hapolas tradition implementation.
APP is a direct target gene of let-7d.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

<p><b>A</b>, The predicted duplex of let-7d, and its target site in the untranslated region (UTR) of APP, as well as the mutations made in the APP 3’UTR. <b>B</b>, The EGFP expression of reporter vector containing the APP 3’UTR in 293T cells was downregulated by let-7d, and that of the reporter vector containing the mutated APP 3’UTR was not suppressed. *p<0.05, n = 4 per group. <b>C</b>, The expression of APP and Aβ in 3 groups. Compared to the other 2 groups, the expression level of APP and Aβ was significantly increased in 6-hour group. GAPDH expression was used as a loading control. The expression of APP and Aβ was normalized by the expression of the GAPHD. The relative APP and Aβ expression was calculated in relation to that in control group. The experiments had been repeated four times and the results were similar to the one shown. *p<0.05 vs. control, <b>#</b>p<0.05 vs. 2-hour group, n = 4 per group.</p>
Karteziánské tělo

Field: Arts and Humanities (Social Sciences)

The aim of the thesis is to make a resume for a view of body and corporality in relationship with the existence and cognition aspect to res cogitans and res extensa. The issue provides analysis of Cartesian's world extension and its reach over to present time through symbols, medicines and religion. Simultaneously the essence of authentic life in the truth as the most important essence and sense of life's existence is given as well. Keywords: Body, corporality, body scheme, truth, authenticity
Receipt for payment from Mary C. Cocke and Edward Cocke to Conelly and Walton, March 19, 1842

Field: Arts and Humanities (Social Sciences)

This document is part of the John Cocke papers that contains the personal, business, and legal papers of this 19th century Marengo County, Alabama, plantation owner, who not only managed his own plantation but also served as an agent for various family members. Financial papers consist of receipts from grocers and suppliers detailing purchases (including slave purchases); account books for his blacksmith shop; and labor accounts with payroll. There are cotton records that contain correspondence as well as accounts.
Relationship between cognitive age and technology readiness: an exploratory analysis of mature consumers

Field: Psychology (Social Sciences)

Cognitive age is an important concept in the study of mature consumers. The present study examines the association between cognitive age and technology readiness and adoption of technologies among mature consumers. Findings suggest that mature consumers perceive \nthemselves to be cognitively younger than their actual age. Cognitively younger mature consumers are more likely to be Explorers holding more positive feelings towards technology \nreadiness. Adoption of self-service banking technologies and other technologies appear to decrease, with an increase in cognitive age. The inclusion of cognitive age in this study has provided an alternative insight into the mature consumer market.
Oral cannabinoids in people living with HIV on effective antiretroviral therapy: CTN PT028—study protocol for a pilot randomised trial to assess safety, tolerability and effect on immune activation

Field: Medicine (Health Sciences)

Introduction Despite antiretroviral therapy (ART), people living with HIV have higher rates of non-infectious chronic diseases. These conditions are driven by relatively high levels of inflammation persisting on ART compared with uninfected individuals. Chronic inflammation also contributes to HIV persistence during ART. Cannabis when taken orally may represent a way to reduce inflammation and strengthen immune responses. Before planning large interventional studies, it is important to ensure that cannabis taken orally is safe and well tolerated in people living with HIV. We propose to conduct a pilot randomised trial to examine the safety and tolerability of cannabis oils containing tetrahydrocannabinol (THC) and cannabidiol (CBD) consumed orally in people living with HIV. We will also measure inflammatory markers, markers of HIV persistence in peripheral blood cells and changes in the gastrointestinal microbiome. Methods and analysis Twenty-six people living with HIV having undetectable viral load for at least 3 years will be randomised to receive TN-TC11LM (THC:CBD in 1:1 ratio) or TN-TC19LM (THC:CBD in 1:9 ratio) capsules daily for 12 weeks. Safety and tolerability of these capsules will be assessed through haematological, hepatic and renal blood tests, face-to-face interviews and questionnaires. Proportions of participants without any signs of significant toxicity (grades 0–2 scores on the WHO toxicity scale) and who complete the study, as well as scores on quality of life and mood will be examined using descriptive statistics. The effects on inflammatory markers, markers of peripheral blood reservoir size and effect on the composition of the gastrointestinal microbiome will be assessed before and after study completion. Ethics and dissemination This study has been approved by the Research Institute of the McGill University Health Centre. A Data Safety Monitor will review safety information at regular intervals. The final manuscript will be submitted to an open-access journal within 6 months of study completion. Trial registration number NCT03550352 .
Struktur Modal pada UMKM Tahu di Kelurahan Tinalan Gang IV Kota Kediri dan Menurut Perspektif Islam

Field: Business, Management and Accounting (Social Sciences)

<p><em>The development of MSMEs (Small, Micro and Medium Enterprises) has several problems, one of them is the capital problem. Lack of capital affected the development rate of MSMEs. It is because most MSMEs use their own capital, so the capital is not too large. One of the reasons MSMEs use their own capital is because of high loan interest and complicated requirements. The importance of capital in a company, so the company must plan the capital appropriately. The purpose of this study was to determine the capital structure of the tofu MSMEs in Tinalan Kelurahan IV, Kediri. This study also aims to know the reason of the business owners use their own funds or external funds that can help their businesses survive and the perception of MSME owners about the increase in capital will affect on the profits. In addition, the research aims to know the reason of business owners saving their funds at home instead of the bank. The method of this research is qualitative research with descriptive approach. This study uses 9 informants from entrepreneurs that include in categories. Data collection techniques use interview and questionnaire. The results showed that the majority of entrepreneurs prefer to use their own capital rather than from banks/ other partnerships, the majority of MSME owners prefer to save their funds at home and they still had low literacy/knowledge of financial.</em></p>
Labor Market Outcomes for Legal Mexican Immigrants Under the New Regime of Immigration Enforcement*

Field: Economics, Econometrics and Finance (Social Sciences)

Objectives. This article documents the effects of increasingly restrictive immigration and border policies on Mexican migrant workers in the United States. Methods. Drawing on data from the Mexican Migration Project, we create a data file that links age, education, English‐language ability, and cumulative U.S. experience in three legal categories (documented, undocumented, guest worker) to the occupational status and wage attained by migrant household heads on their most recent U.S. trip. Results. We find that the wage and occupational returns to various forms of human capital generally declined after harsher policies were imposed and enforcement dramatically increased after 1996, especially for U.S. experience and English‐language ability. Conclusion. These results indicate that the labor‐market status of legal immigrants has deteriorated significantly in recent years as larger shares of the migrant workforce came to lack labor rights, either because they were undocumented or because they held temporary visas that did not allow mobility or bargaining over wages and working conditions.
A SPECIAL SYRINGE FOR DISPLACEMENT IRRIGATION OF THE NASAL SINUSES

Field: Health Professions (Health Sciences)

A short time ago, I1described in this journal a new method for the introduction of fluids into the nasal accessory sinuses, which I termed "displacement irrigation." It consists, briefly, in inverting the head; introducing fluid into the upturned nose, and causing it to enter the sinuses by exhausting air from them and allowing the fluid to replace it. Various solutions have been employed for their cleansing and therapeutic effects, and iodized oils have been introduced for roentgen-ray examination. The apparatus that was used in the beginning consisted of a 5 cc. glass plunger syringe for introducing the fluid, and an electric suction pump to produce the vaccuum. This arrangement proved somewhat cumbersome, especially in the roentgen-ray laboratory, and necessitated a trip to the roentgenologist with the patient in order to introduce the oil at the proper moment. Displacement syringe In order to simplify the procedure
Additional file 1 of A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Additional file 1: Fig S1. The cis-regulatory-directed bioinformatic pipeline for Psmd7 as an example. Fig S2. Distribution of gene expression values in the mouse embryonic heart E14.5. Fig S3. Properties of CREs. Fig S4. Overlap of predicted genes with genes harbouring de novo mutations associated with congenital heart disease. Fig S5. Expression and regulation of the experimentally validated genes. Table S1. List of genes that are regulated by enhancers and promoters specifically active in the heart, and known defects associated with these genes in human, and mouse and zebrafish models. Table S2. Evidence for new genes predicted to be involved in heart development or disease. Table S3. RNAi lines used for cardiac-specific knockdown in Drosophila.
Stimulation of Erythropoiesis in Irradiated Dogs and Rats

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Following whole body exposure to sublethal doses of X-rays, erythropoiesis was depressed in both dogs and rats, but could be markedly increased by bleeding the animals shortly before or after irradiation. In rats, post-irradiation administration of PAPP resulted in a similar increase in erythropoiesis. Blood loss 24 hours after irradiation had no appreciable effect. The data indicate the reversibility or modification of injury to the erythropoietic system without similarly affecting the recovery of other bone marrow elements.
Development and validation of a nomogram for predicting survival in Chinese han patients with resected colorectal cancer

Field: Medicine (Health Sciences)

Background Estimates of survival after curative colorectal cancer (CRC) surgery are the basis of patient care and treatment planning. A nomogram is a useful tool for individualized cancer prognosis. Methods A total of 2450 patients with nonmetastatic CRC were included to develop a nomogram. Prognostic factors were identified and integrated by the Cox proportional hazards model. Then, we developed and validated a prognostic nomogram. The performance of this model was assessed by the concordance index (C‐index) and a calibration curve. The nomogram was internally validated by bootstrapping and externally validated with a separate database of 299 patients from The Cancer Genome Atlas. Results Age, T stage, N stage, histological type, tumor location, lymph‐vascular invasion, preoperative carcinoembryonic antigen, and sample lymph nodes were integrated into the nomogram. The C‐index of the nomogram for predicting overall survival was higher than that of the seventh edition American Joint Committee on Cancer TNM staging system (training data set, 0.76 vs 0.68, respectively; P < 0.001; validation data set, 0.78 vs 0.69, respectively; P = 0.003). Conclusion We developed a prognostic nomogram for patients with nonmetastatic CRC, which could provide a more individualized outcome prognostication than that afforded by the TNM staging system by using common clinicopathologic factors.
Development of hybrid super-capacitor and lead-acid battery power storage systems

Field: Energy (Physical Sciences)

Abstract Because the electricity storage of renewable energy is irregular, the battery in this system will be impacted by current. This will also have a negative impact on the battery life, increase the project cost and lead to pollute the environment. This study proposes a method to improve battery life: the hybrid energy storage system of super-capacitor and lead-acid battery is the key to solve these problems.
Motivace a osobnost

Field: Psychology (Social Sciences)

The famous book by Abraham H. Maslow's Moti­vation and Personality is one of the seminal psychological works of the 20th century. It is therefore only to be welcomed that its second, expanded and revised edition from 1970 is now available in Czech translation for the first time. The book consists of sixteen chapters and two appendices. In the first of these, Maslow deals with the problems generated by the positive approach in psychology. Maslow commonly uses the term positive psychology here, which he introduced in 1954 in the first edition of his book, so that he is considered one of the forerunners or founders of this movement. In the second appendix, the author emphasizes his belief in the need to move from the study of partial psychological problems or domains to a holistic-dynamic approach.
Batesiana et Martinezia, nouveaux genres d'Euparini (Coleoptera : Scarabaeidae : Aphodiinae) du nouveau monde

Field: Agricultural and Biological Sciences (Life Sciences)

In this paper, the author explains how he has been lead to examine the New World Eupariini types and to revise the tribu of this area, after his antillean Scarabs usual studies and mainly from the Ataenius species inhabiting the West Indies. Two genus (Batesiana and Martinezia) and two species owning to the second one (Martinezia dutertrei and cambeforti), all new to Science, are described. The remaining species are removed from different genus and assigned to Batesiana (one taxon) and Martinezia (six taxa). Their geographical repartition is given and the biological informations, as published by various authors and mainly for Martinezia dutertrei Chalumeau (excavaticollis Auct.), are reviewed. Two lectotypes plus two paralectotypes are labelled, and two holotypes are pointed. The species aedeagus and different body's parts are figured.
Searching for New Physics with $B^{0} \to K^{*0} \mu^+ \mu^-$

Field: Physics and Astronomy (Physical Sciences)

One of the main indications for New Physics in rare $B$-decays is deduced\nfrom the tension between experimental and Standard Model predictions of the\nangular analysis of the $B^0 \\to K^{*0} \\mu^+\\mu^-$ decay. There are however\npossible non-local hadronic effects which in principle can also explain these\ntensions. In this work, we consider a statistical approach for differentiating\nthe source of the tension in $B^0 \\to K^{*0} \\mu^+\\mu^-$ observables and we\nalso investigate the prospects of such a comparison with future data from the\nLHCb experiment.\n