jimnoneill/paper-to-field-training huggingface dataset:
Innovative psychological first aid (PFA) in the new normal for frontliners

Field: Health Professions (Health Sciences)

Abstract Purpose Psychological first aid (PFA) is utilized in the direct aftermath of crisis events. As the world grappled with Covid‐19, PFA was provided for staff members in Hospital Sultan Ismail. In adherence to the New Normal, innovative approaches had to be taken. We engaged clients through virtual communication methods. PFA Solat was organized to assist Muslim staff fulfil religious obligations while being on the frontlines. Conclusions PFA may be useful in helping frontline staff manage stress associated with the increased workload and general anxiety relating to the pandemic. Practice Implications It is recommended all staff members, especially those involved in frontline duty, to be provided PFA.
Missing Treasures: Tracking Lost Ladino Books

Field: Arts and Humanities (Social Sciences)

Abstract A comprehensive project conducted over the past few years to locate and document every book printed in Ladino, revealed that between the years 1490–1960, nearly four thousand titles were published. In this article, I will show that many Ladino books were lost over the generations. Some of those missing books were referenced in assorted sources. Others did not come to researchers’ attention until fairly recently. This study contains several examples of Ladino books from the 16th century, which were lost and then rediscovered – due to the fact that their fragments were preserved in the Cairo Genizah or found in the bindings of antique books.
Supplementary Figure 1 from Activation of the NF-κB Pathway by the STAT3 Inhibitor JSI-124 in Human Glioblastoma Cells

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

<p>PDF file - 135K, JSI-124 inhibits stimulus-induced and constitutive JAK2/STAT3 phosphorylation and inhibits proliferation in GBM cells.</p>
Effect of elevated CO2 and temperature on the life cycle of pink bollworm, Pectinophora gossypiella (Saunders) mediated by Bt cotton

Field: Agricultural and Biological Sciences (Life Sciences)

Pink bollworm, Pectinophora gossypiella (Saunders) is the notorious pest and being a monophagy on cotton, the damage that it causes is alarming. Any changes in the nutritional quality of cotton will have direct influences on pink bollworm. In this regard, the host-mediated effect of eCO2 and temperature on the life cycle of pink bollworm, P. gossypiella on Bt cotton was studied in the open top chambers at the Center for Agro-climatic Studies, UAS, Raichur. The results revealed that variations in phyto-chemistry of Bt cotton particularly the cry toxin expression and nitrogen have reduced in elevated CO2 and temperature conditions which also reduced larval, pupal period, adult longevity, fecundity and incubation period. However, the total life span of pink bollworm did not show statistically significant differences among the climate change treatments. Similar results were noticed when pink bollworm was reared on Bt cotton collected from different open top chambers and reared separately in growth chambers and the same larvae were analyzed for their enzyme activity. A significant increase in the activity of midgut proteases (trypsin and chymotrypsin), carbohydrases (α-amylase) was noticed but lipase activity was reduced.
Effect of proton beam irradiation on survival and seedling growth parameters of Indian rice (Oryza sativa L.) variety ‘Indira Barani Dhan 1’

Field: Agricultural and Biological Sciences (Life Sciences)

Rice crop, a staple food for a majority of population across the world, holds a significant role to play in alleviating the global hunger problem. Enhancement of genetic diversity of rice will serve to overcome constraints in sustained and ecologically effective improvement in the production of quality rice, challenged by erratic patterns of global climate, changing pest dynamics, resource availability in proportion to growing population etc. Proton ion beam has sprung up as a promising novel mutagen in the mutation breeding of crop plants, by virtue of its higher LET values, causing higher frequency of mutations. Dose optimization is pre-requisite to obtain a range of phenotypic mutants, without drastic reduction in survival and growth subsequently. This study was undertaken to standardize proton beam irradiation dose rate post the evaluation of in-vitro germination, growth and survival of rice variety IBD -1, with doses ranging from 0-500Gy. Doses between 152.47Gy- 253.53Gy were found suitable for mutagenesis, without drastically impairing growth and survival.
Parallelized Dimensional Decomposition for Large-Scale Dynamic Stochastic Economic Models

Field: Economics, Econometrics and Finance (Social Sciences)

We introduce and deploy a generic, highly scalable computational method to solve high-dimensional dynamic stochastic economic models on high-performance computing platforms. Within an MPI---TBB parallel, nonlinear time iteration framework, we approximate economic policy functions using an adaptive sparse grid algorithm with d-linear basis functions that is combined with a dimensional decomposition scheme. Numerical experiments on "Piz Daint" (Cray XC30) at the Swiss National Supercomputing Centre show that our framework scales nicely to at least 1,000 compute nodes. As an economic application, we compute global solutions to international real business cycle models up to 200 continuous dimensions with significant speedup values over state-of-the-art techniques.
Rights and Obligations of the Afghan Government and Citizens in Environmental Protection

Field: Social Sciences (Social Sciences)

This research examines the environmental rights and obligations of the Afghan government and citizens, emphasizing collaborative approaches. It investigates government rights, including legislative authority and regulatory oversight, with corresponding obligations such as enacting and enforcing environmental laws. Citizen rights encompass environmental participation and access to information, with obligations like responsible consumption and conservation support. The study highlights collaborative rights involving public-private partnerships and international cooperation, emphasizing joint decision-making and resource sharing. The findings stress collective action, utilizing case studies and examples, and recommend strategic focus areas for both government and citizens, including Monitoring and Evaluation, Public-Private Collaboration, Regulatory Oversight Improvement, and Legislative Framework Strengthening. The research contributes to environmental governance understanding in Afghanistan, guiding sustainable development and conservation strategies.
Complex sleep‐disordered breathing after vagus nerve stimulation: broadening the spectrum of adverse events of special interest

Field: Medicine (Health Sciences)

Abstract Two young males with refractory epilepsy of unknown aetiology were referred for vagus nerve stimulation (VNS). Sleep disturbances emerged following VNS parameter changes. In Patient 1, video‐polysomnogram (PSG) disclosed snoring and catathrenia in non‐REM sleep. Central apnoea also occurred, but more rarely. In Patient 2, video‐PSG showed mixed apnoea with desaturation and episodes of stridor followed by a catathrenia‐like sound. A drug‐induced sleep endoscopy (DISE) revealed, during VNS OFF time, glossoptosis, “trap door” of the epiglottis, and paresis of the left side of the larynx and ipsilateral vocal cords. During ON time, there were periods of pharyngeal collapse, in which video‐PSG revealed patterns suggestive of both obstructive and central sleep apnoea. All these sleep‐related phenomena were coincident with VNS ON time. In the first patient, VNS parameter adjustment was sufficient to successfully reverse all the symptoms, whereas the other patient required concomitant treatment with continuous positive airway pressure. The data broaden our knowledge about sleep disorders related to VNS, in particular stridor and catathrenia. We suggest that central sleep apnoea may be associated with laryngeal occlusion. DISE may be considered in selected cases as a valuable clinical tool to evaluate, in a single session, the effectiveness of multiple VNS parameter changes on respiration and laryngeal side effects. [ Published with video sequences ].
Data and code for figures: Breathing Dissipative Solitons in Optical Microresonators

Field: Physics and Astronomy (Physical Sciences)

This dataset contains the data presented in the Figures of the paper Breathing dissipative solitons in optical microresonators (doi:10.1038/s41467-017-00719-w). The data for figure X is gathered in one matlab dataset file FigureX_Dataset.mat, under a structure variable figX whose fields are the panels of the figure in the manuscript (a,b,c,...). In each of the panel field, you find subfields X, Y, Z that each are cell arrays containing the (X,Y,Z) data for all the lines / surfaces presented in the panel. In order to plot the line #1 of panel b of figure 3 you can proceed as follow: load Figure3_Dataset.mat
plot(fig3.b.X{1}, fig3.b.Y{1})
A minimal script FigureX_process.m is provided for each figure in order to plot all the panels. For some insets of Figures 1,2,4, the structure is slightly modified, please refer to the scripts for detail access of the data. The datasets and scripts were generated and tested using Matlab 2017 or 2014.
Ambient temperature during pregnancy and risk of maternal hypertensive disorders: a time-to-event study in Johannesburg, South Africa

Field: Medicine (Health Sciences)

BACKGROUND AND AIM: Hypertensive disorders in pregnancy are a leading cause of maternal and perinatal mortality. We evaluate the effects of ambient temperature on risk of maternal hypertensive disorders throughout pregnancy. METHODS: We used birth register data for all singleton births (22-43 weeks' gestation) recorded at a tertiary-level hospital in Johannesburg, South Africa, between July 2017-June 2018. Time-to-event analysis was combined with distributed lag non-linear models to examine the effects of mean weekly temperature, from conception to birth, on risk of (i) high blood pressure, hypertension, or gestational hypertension, and (ii) pre-eclampsia, eclampsia, or HELLP (hemolysis, elevated liver enzymes, low platelets). Low and high temperatures were defined as the 5th and 95th percentiles of daily mean temperature, respectively. RESULTS: Of 7986 women included, 844 (10.6%) had a hypertensive disorder of which 432 (51.2%) had high blood pressure/hypertension/gestational hypertension and 412 (48.8%) had pre-eclampsia/eclampsia/HELLP. High temperature in early pregnancy was associated with an increased risk of pre-eclampsia/eclampsia/HELLP. High temperature (23°C vs 18°C) in the third and fourth weeks of pregnancy posed the greatest risk, with hazard ratios of 1.76 (95% CI 1.12-2.78) and 1.79 (1.19-2.71), respectively. High temperatures in mid-late pregnancy tended to protect against pre-eclampsia/eclampsia/HELLP. Low temperature (11°C) during the third trimester (from 29 weeks' gestation) was associated with an increased risk of high blood pressure/hypertension/gestational hypertension, however the strength and statistical significance of low temperature effects was reduced with model adjustments. CONCULSIONS: Our findings support the hypothesis that high temperatures in early pregnancy increase risk of severe hypertensive disorders, likely through an effect on placental development. This highlights the need for greater awareness around the impacts of moderately high temperatures in early pregnancy through targeted advice, and for interventions that reduce heat exposure among pregnant women. The potential ameliorating effects of high temperature in mid-late pregnancy requires further exploration.
On higher-order affine distributions

Field: Mathematics (Physical Sciences)

The aim of the paper is to provide a discussion on the notion of nonlinear interaction between scales. This notion is extremely important in the study of nonlinear physical phenomena, such as the study of the energy cascade in fully developed turbulence in fluids. The discussion is centered on the temptative definition of higher-order time-multiscale distributions. A simple answer which we call the biscalogram enlightens the main difficulty arising in our attempt to define nonlinear interactions between scales. Some simulations illustrate that point. Furthermore, two different classes of higher-order time-multiscale distributions are proposed, the first one based on a set of affine covariance properties, the other on a set of invariance-covariance properties.
229-OR: The Accuracy of a Novel Continuous Ketone Monitoring System (CKM) and Metrics of Ketosis during Ketogenic Diets in Type 1 Diabetes (T1D)

Field: Medicine (Health Sciences)

Introduction and Objective: We evaluated i) the accuracy of SiBio CKM and ii) continuous ketone levels during two ketogenic diets, in individuals with T1D on automated insulin delivery (AID). Methods: We compared the readings of the CKM on day 7 of wear age to capillary measurements by FreeStyle Libre 2 ketone meter in adults who underwent 8-hour inpatient insulin suspension experiments. We also assessed metrics of continuous ketone levels using the CKM on two 6-day ketogenic diets: very-low carbohydrate diet (&lt;50 g/day) and intermittent 12-hour fasting in outpatient free-living settings. Results: During insulin suspensions, 181 paired data points were collected from 14 adults (10 female, mean age of 36.5 y, HbA1c 6.9%, insulin dose 0.72 units/kg). The overall mean absolute difference (MAD) between the CKM and capillary readings was 0.2 mmol/L and the relative MAD for ketone values ≥0.6 and ≥1.0 mmol/L were 24% and 20%, respectively. During the ketogenic diets, the percent time with CKM values &lt;0.6 and ≥0.6 mmol/L were 97.9% and 2.1% (30 min/day), respectively. The number of continuous ketosis events &gt;0.6 and &gt;1.0 mmol/L of more than 30 minutes were 51 and 7 events (i.e., 1 event in 2.7 and 20 days), respectively, with an average duration of 77 min/event; all events were asymptomatic. Conclusion: SiBio CKM demonstrated acceptable accuracy and reveals that benign, transient ketosis may be common in T1D. Disclosure N. Sabelli: None. A. Haidar: Research Support; Tandem Diabetes Care, Inc. Consultant; Eli Lilly and Company, Abbott. Research Support; ADOCIA, Dexcom, Inc., Ypsomed AG, Bigfoot Biomedical, Inc. D. Majdpour: None. M. Pasqua: Speaker's Bureau; Abbott, Sanofi, Medtronic. M. Tsoukas: Speaker's Bureau; Novo Nordisk, Eli Lilly and Company, Boehringer-Ingelheim, Janssen Pharmaceuticals, Inc, Sanofi. N. Perz: None. S. Jacobson: None. Funding Diabetes Quebec (Subvention de m?rite)
A Survey on Smart Parking Management System

Field: Computer Science (Physical Sciences)

With the large increase in population, automated industries and need of vehicles, parking of the vehicles is becoming a critical issue in various cities. Unmanaged parking of vehicles leads to noise pollution, air pollution, traffic congestion. During peak hours, it is difficult task to find vacant parking lot and it becomes the major challenge for driver to park the vehicle. A lot of work is being done in the whole world to manage the efficient parking of vehicles. To give the clear overview about efficient parking system, we go through some existing studies over the period of 2009-2022 which proposed various parking solutions. This survey gives an exhaustive study of available parking solutions and also proposed som
Językowy i tekstowy obraz Mazura na podstawie twórczości Stefana Rudanskiego

Field: Arts and Humanities (Social Sciences)

Linguistic and Textual Image of Mazur in Poetry by Stepan Rudans’kyy The main issue discussed in this article is the linguistic and textual image of Mazur in the poetry by Stepan Rudans’kyy. Rudans’kyy invented his own poetic form called “spivomovka”, which was inspired by Ukrainian folklore. Those humorous poems mainly focused on describing local types of Podolia ethnic groups, such as Cossacks, Ruthenians, Russians (Moskal), rabbis, Polish colonists (Mazur –[Mazovian], Lach). The creation of Mazur in poems by Rudans’kyy was largely influenced by the image of Mazur in the Ukrainian and Polish folklore. The linguistic and textual images of the character are created by Mazur’s replies, as well as descriptions of his activity. Mazur is characterized by the following features: sincerity, simplicity, naivety, superficial religiousness and cheerfulness. Through presenting the characteristics of Mazur, the author also draws our attention to the important issue of the lack of code that would be common to the interlocutors, both in terms of linguistics and culture.
Insect population responses to environmental stress and pollutants

Field: Agricultural and Biological Sciences (Life Sciences)

Insects and other related arthropods make up about 90% of all plant and animal species in the world. They are vital to the functioning of the ecosystem and biosphere, and neither of these systems can operate effectively without insect interactions. Because of their major ecological and economic roles in nature and society, the beneficial and pest activities of insects need to be clearly understood. Insect populations are being stressed directly by the action of temperature, moisture, and a wide array of chemical Ö öpollutants (pesticides, fertilizers, air pollutants, and numerous other chemicals) that are dispersed through air, water, and soil. Insects are affected by this same group of stresses indirectly, through their food plants, parasites, and predators. Depending on the species and the particular stress affecting it, insect populations respond by increasing or decreasing in numbers. The responses of insect populations to various direct and indirect environmental stresses and chemical pollutants are assessed. Some insect populations increase, while others decline. The responses were determined by the particular environmental stress, the insect species, and the stage at which they were exposed to the stress.Key words: insects, environment, pollutants, stress, water, herbicides.
Research Progress on Combined Chinese and Western Medicine Treatment of Mycoplasma pneumoniae Pneumonia in Children

Field: Medicine (Health Sciences)

With the continuous development of medical technology, combined treatment of Chinese and Western medicine has gradually become a research hotspot. As a common disease in pediatrics, the treatment of Mycoplasma pneumoniae pneumonia (MPP) in children is also being explored and improved. This article summarizes the research progress of combined Chinese and Western medicine treatment of MPP in children in recent years, aiming to provide a useful reference for the combined treatment of MPP in children. The article firstly introduces the etiology and pathogenesis of MPP in children, thereafter briefly introduces the Western anti-infective treatment and traditional Chinese medicine (TCM) diagnosis and treatment of MPP in children, and lastly introduces the methods of combined treatment of TCM and Western medicine in detail. The article points out that the combination of Chinese and Western medicine can give full play to the overall regulation of Chinese medicine and the precise treatment advantages of Western medicine, improve the therapeutic effect, reduce the use of antibiotics, and lower the recurrence rate of the disease, which is worthy of further research and promotion.
Stability of a Natural-Based Cream Containing Lecythis pisonis Extract.

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The outer pericarps of Lecythis pisonis Camb. are by-products with a high content of antioxidant substances. The goal of the present study was to analyze the incorporation of L. pisonis pericarp extract in an all-natural formulation. Physical-chemical and organoleptic characteristics and Challenge tests were evaluated before and after the stability test of the cosmetic formulation. The instability of the formulation increased with the increase of the concentration of the extract. The physical-chemical and organoleptic parameters did not present alterations after the stability test. The extract of the outer pericarp of L. pisonis seems to be compatible with the cream formulation. However, the concentration should be analyzed to not interfere with the stability of the product. The natural formulation developed is under the legal requirements of the National Agency of Sanitary Monitoring of Brazil (Agência Nacional de Vigilância Sanitária), presenting an efficient conservation system.
Calcium-induced spikes in cultured pigment epithelium of chick retina.

Field: Neuroscience (Life Sciences)

Resting membrane potentials, electrical resistance, and coupling of chick retinal pigment epithelium cells in tissue culture have been measured with micropipette electrodes. Topical application of NaCl, KCl, MgCl2, and CaCl2 produce rapid, reversible changes in the membrane potentials of these cells. CaCl2 uniquely induces a slow hyperpolarizing wave that can lead to barrages of depolarizing action potentials or spikes and a slow, reversible vacuolization of the cells.
Data from Osimertinib and Selpercatinib Efficacy, Safety, and Resistance in a Multicenter, Prospectively Treated Cohort of <i>EGFR</i>-Mutant and <i>RET</i> Fusion-Positive Lung Cancers

Field: Medicine (Health Sciences)

<div>AbstractPurpose:<p>Acquired <i>RET</i> fusions have been reported at resistance to treatment with EGFR inhibitors in <i>EGFR</i>-mutant non–small cell lung cancer (NSCLC); however, a multicenter cohort of patients with <i>EGFR</i>-mutant lung cancers treated with osimertinib and selpercatinib for <i>RET</i> fusion–mediated osimertinib resistance has not previously been published.</p>Patients and Methods:<p>Patients who received selpercatinib in combination with osimertinib on a prospective expanded access clinical trial (NCT03906331) and single-patient compassionate use programs across five countries were centrally analyzed. All patients had advanced <i>EGFR</i>-mutant NSCLC with a <i>RET</i> fusion detected from tissue or plasma following osimertinib therapy. Clinicopathologic and outcomes data were collected.</p>Results:<p>Fourteen patients with <i>EGFR</i>-mutant and <i>RET</i> fusion–positive lung cancers who experienced prior progression on osimertinib received osimertinib and selpercatinib. <i>EGFR</i> exon 19 deletions (±T790M, 86%) and non-<i>KIF5B</i> fusions (<i>CCDC6-RET</i> 50%, <i>NCOA4-RET</i> 36%) predominated. Osimertinib 80 mg daily and selpercatinib 80 mg twice daily were the most commonly administered dosages. The response rate, disease control rate, and median treatment duration were 50% [95% confidence interval (CI), 25%–75%, <i>n</i> = 12], 83% (95% CI, 55%–95%), and 7.9 months (range, 0.8–25+), respectively. Resistance was complex, involving EGFR on-target (<i>EGFR</i> C797S), RET on-target (<i>RET</i> G810S), and off-target (<i>EML4–ALK/STRN–ALK</i>, <i>KRAS</i> G12S, <i>BRAF</i> V600E) mechanisms; <i>RET</i> fusion loss; or polyclonal mechanisms.</p>Conclusions:<p>For patients with <i>EGFR</i>-mutant NSCLC with an acquired <i>RET</i> fusion as a mechanism of EGFR inhibitor resistance, the addition of selpercatinib to osimertinib was feasible and safe and offered clinical benefit, supporting the prospective evaluation of this combination.</p></div>