jimnoneill/paper-to-field-training huggingface dataset:
Combined Chemotherapy with Fludarabine, Cyclophosphamide and Rituximab (FCR) for Relapsed or Untreated Progressive Chronic Lymphocytic Leukemia (CLL). A Single Center Experience.

Field: Medicine (Health Sciences)

Abstract Introduction: During the last decade, strong prognostic factors and new compounds emerged for the treatment of CLL. The initial experience with the combination of FCR at MDACC as salvage therapy and later in untreated patients (pts) promote us to use these regimen since March 2001. Purpose: To evaluate the efficacy of FCR in improving the complete remission (CR), disease free survival (DFS) and overall survival (OS) rates in pts previously treated with chlorambucil-prednisone as a single therapy and untreated CLL pts. Patients and methods: A total of 32 CLL pts, 16 after relapse and 16 untreated with progressive disease completed treatment and evaluation, 3 pts are still on treatment. FCR consisted of Fludarabine 25 mg/m2 iv on days 1 to 3, Cyclophosphamide 250 mg/m2 iv on day 1 to 3 and Rituximab 375 mg/m2 iv on day 1 given at 4 weeks interval up to 4–6 cycles. Response was assessed 4–8 weeks after treatment. CR was defined by CLL/NCI-WG. Minimal residual disease (MRD) negative was defined as &lt;1% CD19, CD5 positive cells in peripheral blood and bone marrow as assessed by three colour flow cytometry. Median age was 63 years (range 34–80). Binet’s clinical stage were A: 9%, B: 31% and C: 60%. The CD38 expression was positive (&gt;7% of cells) in 53% and negative in 47% of the cases. Results: The CR was obtained in 66% of the pts, nodular partial remission (NPR) in 19%, PR in 9% and stable disease in 6%. Characteristics Pts. # % CR % MRD negative % DFS 24 mo P= # OS 24 mo P= Untreated Pts 16 81 100 81 0.64 90 0.81 Treated Pts 16 50 81 76 87 CD38 Positive 17 65 82 65 0.01 80 0.28 CD38 Negative 15 67 87 100 100 Total 32 66 84 78 89 Neutropenia grade 3–4 was observed in 31% of the courses, 5% of the pts required hospitalisation due to infeccious episodes. Conclusion: In patients with CLL, FCR induce a high CR, MRD negative and DFS rate. Patients with CD38 negative expression correlated with a better DFS.
A Prospective Study of Intrapulmonary Fat Accumulation in the Newborn Lung Following Intralipid Infusion

Field: Medicine (Health Sciences)

In order to assess the safety and stability of a parenteral fat emulsion (Intralipid 8 ) in total parenteral nutrition (TPN), 29 infants were infused Vamin glucose and Dextrose electrolyte solution as well as one of two isocaloric regimens; either 25 % Dextrose (Group I) or 10 % Intralipid (Group II). Regular biochemical monitoring was performed in all cases and no infants became lipaemic nor developed abnormally high levels of total free fatty acid. Eight infants died and only those who had received fat emulsion had lipid staining material distending the pulmonary vessels. One infant having low infusion rates of Intralipid had massive fat accumulation in the lungs, but biochemistry during life had been normal. We speculate that in ill infants the emulsion becomes less stable and agglomeration of fat particles occurs which are then fully filtered out by the lungs before metabolism of the exogenous fat can occur.
Signs sculptured in stone

Field: Arts and Humanities (Social Sciences)

Journal Article Signs sculptured in stone Get access Boileau Boileau Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume s7-VIII, Issue 207, 14 December 1889, Page 475, https://doi.org/10.1093/nq/s7-VIII.207.475e Published: 14 December 1889
Additional file 14: of Phylogenetic relationships of the New World titi monkeys (Callicebus): first appraisal of taxonomy based on molecular evidence

Field: Agricultural and Biological Sciences (Life Sciences)

Partitioning schemes and substitution models selected by PartitionFinder. The selected partitioning schemes were implemented in RAxML v. 8.1, MrBayes 3.2.3 or BEAST v 1.8.1. Numbers in parentheses refer to codon position for coding mitochondrial and nuclear sequences. (XLSX 28 kb)
Happiness Management Within Communication Skills Development and Satisfaction in the Classroom

Field: Social Sciences (Social Sciences)

Managing happiness is a vital pillar that complements students' academic curricula. Therefore, this book chapter aims to describe the relationship between classroom satisfaction, communication skills acquisition, and happiness to enhance the overall happiness of the educational environment. Partial least squares structural equation modelling was employed to validate two hypotheses in our measurement model. They are related to the positive effect of satisfaction and the acquisition of communication skills for happiness. Both relationships are significant, in which happiness is explained more by satisfaction than communication skills. The effect of the specific dimensions of the variables under study is also described. Additionally, we must highlight that females are generally perceived greater rewards and more effectively designed lessons than males. In particular, some groups of students, such as German and Lithuanians, showed lower motivation levels and perceived fewer rewards and less engaging lessons.
EFFECT OF BLOCK SCALE AND REYNOLDS NUMBER ON WAVE FORCE REDUCTION BY WAVE ABSORBING WORKS

Field: Engineering (Physical Sciences)

Effect of block scale and Reynolds number on model experiment of wave pressure in range of breaking wave was examined on an upright sea wall provided with wave absorbing works.Wave pressure obtained decrease with an increase with following parameters: ratio of incident wave height to block scale, HI/d', Reynolds number, Re, ratio of width of wave absorbing works to wave length, B/L and ratio of width of wave chamber to wave length, l/L.The wave force at the upright seawall taken wave absorbing works is P and the wave force without a wave absorbing works is P0, in addition the ratio of P to P0, is found between 0.12 and 0.92.
Impartial Medical Testimony

Field: Social Sciences (Social Sciences)

An impartial medical testimony program provides in essence for the establishment of panels of outstanding, neu tral experts in each of the branches of traumatic medicine. Whenever the medical claims of the contending parties in per sonal injury lawsuits seem irreconcilable, the court may desig nate a physician from the appropriate panel, who will report his findings to the judge and the respective attorneys and pos sibly testify if the case goes to trial. The program, in concep tion and operation, has a two-fold purpose. It is an important factor in the never ending campaign to reduce court congestion and delays, although far from a cure-all for that problem. It is also a very effective instrument in the pre-trial arsenal of measures designed to make a trial a fair and knowledgeable search for the truth. The impartial medical testimony program serves directly and indirectly to discourage the "battle of ex perts" in the courtroom, which often confuses lay jurors and judges, degrades the judicial process, and stigmatizes two great professions.
Recent demographic situation and processes

Field: Social Sciences (Social Sciences)

Ova demografska rasclamba suvremenog demografskog stanja i procesa u Primorsko-goranskoj županiji temelji se na službenim podatcima džavne statistike. Predmet demografke rasclambe su gradovi, opcine, međuregije i Županija u razdoblju opd 1981. do 2001. godine
ROLUL MEDIULUI CIBERNETIC ÎN APLICAREA CONCEPTULUI DE SMART POWER

Field: Social Sciences (Social Sciences)

"The retrograde, puritanical and belligerent ideologies may seem anachronistic, related to the specificity of the 21st century. The need for understanding the reality augmented by the emergence of new forms of manifestation in international relations is materialised by transposing novelty elements into strategic models specific to the current century. A concrete example is the use, within specialised circles, of the concept of “smart power”, an intelligent combination of punitive actions with the ability of persuasion. This concept incorporates, in a unitary conception, aimed at identifying the optimal solution to ensure strategic success, the specific elements of soft and hard power. Another aspect of everyday reality is the significant use of cyberspace as a means of facilitating the process of fulfilling the goals in different areas of activity, respectively at different levels of society. In this regard, in this paper, the role of the cyber environment in achieving the specific objectives of implementing the strategic concept of “smart power” will be addressed."
Performance of 50 Lebanese barley landraces (Hordeum vulgare L. subsp. vulgare) in two locations under rainfed conditions

Field: Agricultural and Biological Sciences (Life Sciences)

Breeding activities in Lebanon have attributed limited interest to barley and landraces have not been exploited before. In this study, 50 Lebanese barley landraces were experimented rainfed in Northern Bekaa in comparison with two checks, Assi and Rihane-3. Two field trials were conducted, the first at 1000 m a.s.l. and 171.6 mm precipitations, and the second at 648 m a.s.l. and 119.4 mm. Out of the 50 landraces, five named LR9, LR12, LR16, LR30 and LR32 were early in heading and maturity in both trials, similarly to checks. Landraces showed a large variability for yield components, particularly grain number per spike and thousand grain weight. Number of spikes per plant and grain weight per plant were twice greater in Kfardan than Qaa location. The best plant productivity in Kfardan was 3.8 g/plant recorded for LR11 vs. 3.46 g/plant obtained with LR33 in Qaa. The higher yield was recorded in Qaa trial with 255 g/m2 for LR31 and 244 g/m2 produced by LR32, while 211 and 200 g/m2 were recorded in Rihane-3 and Assi checks respectively. Principal components analysis allowed to distinguish several landraces that were clustered next to the checks sharing similar features of plant height, spike length and yield per m2. At the level of individual plants and based on the grain yield per plant, a set of 47 plants were found to be similar or even greater to the checks. These plants should be further evaluated for their agronomic performance within national breeding program.
Issues in Teachers’ Reinterpretation of a Task-based Innovation

Field: Social Sciences (Social Sciences)

Although task-based teaching is frequently practiced in contemporary English language teaching, it is underresearched in state school set-tings. This article contributes to filling this gap in the literature by using qualitative case study data to explore how a task-based innovation was implemented in three primary school classrooms in Hong Kong. Analysis of classroom observation and interview data shows how the case study teachers reinterpreted a new curriculum in line with their own beliefs and the practical challenges occurring in their school contexts. Drawing on classroom episodes, the article highlights three issues that proved problematic when the tasks were implemented: use of the mother tongue, classroom management or discipline problems, and the quantity of target language produced. Implications for the design and implementation of task-based pedagogies in primary school con-texts are discussed. Much of the research into task-based teaching has focused on adultclasses in ESL contexts. As Candlin (2001) observes, however, little
Biology YouTube Videos with Focus Questions: Effects on Student Concept Understanding and Media-literacy Skills

Field: Arts and Humanities (Social Sciences)

This research considers the effects of Biology YouTube videos on the concept understanding and media-literacy skills of students aged fifteen, in the topic areas of Human Digestion, Heredity, Biodiversity and Interactions. A quasi-experimental research design using pretest-posttest was utilize, with students divided into two randomly selected groups: experimental and control. Results revealed that Biology YouTube videos with focus questions are as good as conventional teaching in enhancing student conceptual understanding of the Biology topic areas that were the focus of this study. The study also shows that the strategy also developed media-literacy skills of the students. Furthermore, it was foundthat conceptual understanding positively and significantly influenced media-literacy skills of students and vice-versa. It is recommended that the strategy introduced in this study be used in facilitating media literacy in other allied science subjects, more broadly in other subjects, and in the teaching of media-literacy education to educators and students of different year levels. Keywords: Biology YouTube Videos with Focus Questions, Concept Understanding, Media-literacy Skills DOI: http://dx.doi.org/10.23960/jpmipa/v21i1.pp01-11
Questions about interviewing as a research technique

Field: Social Sciences (Social Sciences)

Major issues arise from interviewing as a research strategy. These issues are not new in themselves, but have a new significance in a climate which emphasises both evidence-based enquiry, and the search for a more powerful users' voice in public services. Questions are raised cregarding both ethical issues concerning what is to count as evidence and methodological issues concerning what is to count as ‘real’ research.
A storm off the charts: a case of thyroid storm due to thyrotoxicosis factitia

Field: Medicine (Health Sciences)

A 39 year-old personal trainer and mother of two presented to the emergency department with one week of constitutional symptoms, dyspnoea and non-productive cough.She was gaunt, diaphoretic and drowsy with the following vitals: HR 160bpm, BP 180/60mmHg, RR 38bpm, SpO2 94% on 55L of high flow nasal prongs at FiO2 0.21 and febrile at 38.8⁰C.An ECG revealed atrial fibrillation with rapid [4]
Local parties, participation and campaigning in post-devolution Scotland

Field: Social Sciences (Social Sciences)

The main findings of the thesis are: Scotland’s local parties are poorly resourced, and rely heavily upon their members and activists to provide them with the facilities they need to continue operating; A degree of ambivalence is evident in local parties both about their place in intra-party relations, and in respect to the impact respondents felt their activities had upon various democratic indicators; Despite some short-term upward movement for two parties in the 1990s, the membership levels of Scottish constituency parties are currently on a downward trend; The membership recruitment and retention activities of Scotland’s constituency parties do not appear to lead to local organisations having higher memberships; Activist density is estimated in relation to membership size, voters and the constituency electorate as a whole. The picture that emerges is of only a small number of members being active between elections in each constituency, while the proportion of local activists to a party’s constituency voters and to the constituency electorate as a whole is also low; Assessment of activity levels demonstrates that sizeable proportions of each party’s organisations are classified as “paper branches” that are virtually inactive between elections. Local parties seem most active in terms of organisational maintenance activities such as holding meetings and fundraising. Where they claim to communicate with the electorate, relatively traditional activities such as leaflet delivery and newsletter publishing predominate; Local parties were relatively well prepared for the 2003 Scottish parliament election. By the simple indicator of numbers of election volunteers, levels of activity increased across all parties between the start and towards the end of the campaign; Constituency parties primarily ran mobilising campaigns in 2003. While they did make conversion efforts, canvassing and polling day activities revolved primarily around parties, own voter, not undecided voters. Campaign activities essentially revolved around traditional methods of campaigning, such as leaflet delivery, and largely failed to embrace ‘new’ or distinctively Scottish aspects of electioneering; Creation of an index of campaigning demonstrated that very few local organisations fell into the high effort category. Instead, the vast majority of each party’s associations were classified as expending medium effort on the 2003 campaign; The impact of various aspects of campaigning upon electoral outcomes was assessed. Particularly important for each party’s constituency organisations was the number of volunteers working for the local party towards the end of the campaign.
Genomics Tools for the Characterization of Genetic Adaptation of Low Input Extensively Raised Chickens

Field: Agricultural and Biological Sciences (Life Sciences)

Evolutionary change emanating from differential contribution of genotypes to the next generation can determine success in survival and reproduction in chickens. For extensively raised chickens reared under low-input production systems in smallholder farming areas, conditions of resources deprivation and exposure to diverse and threatening natural selection pressures are common in many countries worldwide. Numerous studies have demonstrated that village chickens and other extensively raised chicken populations represent a valuable source of biodiversity adapted to the local production conditions and selection pressures. Manipulation of their acquired adaptive genetic diversity depends on unravelling the selection footprints in the genomes of these chickens that could point towards candidate genes for traits that enable the animals to survive under the harsh production environments. This chapter summarizes the evidence for chickens’ adaptation to extreme environments and describes an inventory of modern tools that could be used in characterizing the production systems of chicken genetic resources. The role of natural selection in shaping the biodiversity of chicken genetic resources is discussed. The continued advancement of biotechnological tools to assess chicken populations has been beneficial to research in genetic adaptation. Genomics tools, as evidenced by assays of whole genome and transcriptome sequences, and single nucleotide polymorphism (SNP) genotypes of chickens, now allow analyses of functional genomic regions that are linked to adaptation. The use of these methods to characterize and investigate signatures of selection in the chicken genomes is highlighted. This chapter looks at how information on the selection hotspots in the chicken genomes can be manipulated to improve genetic adaptation in indigenous chicken populations with the desire to transfer the benefits to other chicken breeds raised under similar production systems.
PIEZOELECTRIC SURGERY AS A BOON TO DENTISTRY: A REVIEW

Field: Dentistry (Health Sciences)

Dentistry has undergone signicant advancement and has seen several changing concepts over a decade. One such novel innovation is piezosurgery. Piezoelectric bone surgery or otherwise known as piezosurgery is a novel technique invented by Professor Vercellotti in 1988 to overcome the limitations of traditional instrumentation in oral bone surgery by modifying and improving conventional ultrasound technology. It is a promising, meticulous, and soft tissue sparing system for bone cutting based on low frequency ultrasonic microvibrations. The absence of macro vibration makes the instrument more manageable and allows greater intraoperative control with a signicant increase in cutting safety in the more difcult anatomical cutting zone. The present review compares piezosurgery with the traditional tools and emphasizes on its mechanism of action, instruments, biologic effects, advantages, and limitations, as well as its various applications in the eld of dentistry
INVESTIGATION OVER WATER QUALITY OF RIVERS GANGA AND YAMUNA DURING KUMBH-2019-A CASE STUDY AT PRAYAGRAJ (ALLAHABAD), UTTAR PRADESH, INDIA

Field: Environmental Science (Physical Sciences)

Water is synonymous with life. Water is simply as important as oxygen for breathing. Without water, life as we know it could not have evolved and would die. Rivers have been an integral part of human civilizations from times miserable. Therefore, rivers are considered to be sacred. There are various reasons for river water pollution like urbanization, industrialization, religious activities and many more. Kumbh Mela is considered as one of the greatest religious festivals of Hindus where millions of people gather together for spiritual experiences in godliness. It occurs in four different places. Prayagraj (Allahabad), India is the place where the present study was carried out to assess the impact of changes occurring in the properties of water during Kumbh, 2019. In the present study, the following ten different sampling sites were selected along river Ganga and Yamuna: Ganga Arti Ghat (S1), Daraganj (S2), Shastri Bridge (S3), Saraswati Ghat (S4), Gaughat (S5), Boatclub (S6), Sangam (S7), Arail Kaccahr (S8), Arail Uparhar (S9), Chhatnag (S10). Kumbh fair was held from January 14, 2019 to March 4, 2019. Water samples were collected during the monthly intervals from December 2018 to May 2019. The observed values of different physico -chemical parameters like pH, electrical conductivity, total dissolved solid, total hardness, calcium hardness, magnesium hardness, alkalinity, chloride, dissolved oxygen and biochemical oxygen demand (BOD) of samples were compared with National Standard (BIS, 1991) and International Standards by World Health Organization (WHO). According to the result obtained most of the parameters were within the permissible limit except BOD and hardness which were found to be beyond the permissible limit. However, as per the present investigation and analysis, it was observed that the quality of water was very poor which was not fit for drinking and irrigating purpose etc.