jimnoneill/paper-to-field-training huggingface dataset:
Supplemental Material - Identification and development of TP53 mutation-associated Long non-coding RNAs signature for optimized prognosis assessment and treatment selection in hepatocellular carcinoma

Field: Medicine (Health Sciences)

Supplemental Material for Identification and development of TP53 mutation-associated Long non-coding RNAs signature for optimized prognosis assessment and treatment selection in hepatocellular carcinoma by Chenghao Chu, Daoli Liu, Duofa Wang, Shuangjiu Hu, and Yongwei Zhang in International Journal of Immunopathology and Pharmacology
Sex matters: Men with melanoma have a worse prognosis than women

Field: Medicine (Health Sciences)

Background: In Europe, one of the highest melanoma incidences is found in the Netherlands. Like in several other European countries, females are more prone to develop melanoma as compared to males, although survival is worse for men. Objective: To identify clinicopathological gender-related differences that may lead to gender-specific preventive measures. Methods: Data from the Dutch Nationwide Network and Registry of Histopathology and Cytopathology (PALGA) were retrieved from patients with primary, cutaneous melanoma in the Netherlands between 2000 and 2014. Patients initially presenting as stage I, II and III without clinically detectable nodal disease were included. Follow-up data were retrieved from the Netherlands Cancer Registry. Gender-related differences were assessed, and to compare relative survival between males and females, multivariable relative excess risks (RER) were calculated. Results: A total of 54.645 patients were included (43.7% men). In 2000, 41.7% of the cohort was male, as compared to 47.3% in 2014 (P < 0.001). Likewise, in 2000, 51.5% of the deceased cohort was male compared to 60.1% in 2014 (P < 0.001). Men had significantly thicker melanomas at the time of diagnosis [median Breslow thickness 1.00 mm (interquartile range (IQR): 0.60–2.00) vs. 0.82 mm (IQR: 0.50–1.50) for females] and were significantly older at the time of diagnosis, more often had ulcerated melanomas and melanomas localized on the trunk or head and neck. Over time, survival for females improved while that of men decreased (P < 0.001). RER for dying was 1.37 (95% CI: 1.31–1.45) for men in multivariable analysis. Conclusion: There are evident clinicopathological differences between male and female melanoma patients. After multivariable correction for all these differences, relative survival remains worse for men. Clinicians as well as persons at risk for melanoma should be aware of these differences, as awareness and prevention might lead to a lower incidence and mortality of melanoma. This indicates the need of prevention campaigns integrating and targeting specific risk profiles.
Thioredoxino-mediated reduction of mitochondrial alternative oxidase in the thermogenic skunk cabbageSymplocarpus renifolius

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Thermogenesis in plants involves significant increases in their cyanide-resistant mitochondrial alternative oxidase (AOX) capacity. Because AOX is a non-proton-motive ubiquinol oxidase, the dramatic drop in free energy between ubiquinol and oxygen is dissipated as heat. In the thermogenic skunk cabbage (Symplocarpus renifolius), SrAOX is specifically expressed in the florets. Although SrAOX harbours conserved cysteine residues, the details of the mechanisms underlying its redox regulation are poorly understood. In our present study, the two mitochondrial thioredoxin o cDNAs SrTrxo1 and SrTrxo2, were isolated from the thermogenic florets of S. renifolius. The deduced amino acid sequences of the protein products revealed that SrTrxo2 specifically lacks the region corresponding to the α3-helix in SrTrxo1. Expression analysis of thermogenic and non-thermogenic S. renifolius tissues indicated that the SrTrxo1 and SrAOX transcripts are predominantly expressed together in thermogenic florets, whereas SrTrxo2 transcripts are almost undetectable in any tissue. Finally, functional in vitro analysis of recombinant SrTrxo1 and mitochondrial membrane fractions of thermogenic florets indicated its reducing activity on SrAOX proteins. Taken together, these results indicate that SrTrxo1 is likely to play a role in the redox regulation of SrAOX in S. renifolius thermogenic florets.
Resonance production in relativistic heavy ion collisions in a binary emission model

Field: Physics and Astronomy (Physical Sciences)

Resonance particle ratios and spectra are calculated in the sequential binary emission model for hadrons produced from the decay of a single massive resonance formed in relativistic heavy ion collisions. The sequential model which is quite successful in reproducing the yield ratios for stable hadrons at energies currently available at the BNL Relativistic Heavy Ion Collider (RHIC) is found to describe remarkably well the yield ratios for the resonances ${K}^{*}(892){}^{0}$ and \ensuremath{\phi} mesons. The model indicates a short expansion time between the average chemical and thermal freeze-out with negligible regeneration of the resonances via the inverse two-body elastic collision process. Model estimates of the yield ratios for the strange baryons $\ensuremath{\Lambda}(1520)$ and $\ensuremath{\Sigma}(1385)$ are presented.
A Systematic Review of Pica and Geophagy in Japan and Korea

Field: Medicine (Health Sciences)

Pica, the craved and purposive consumption of non-food substances, is a globally widespread behavior that has critical connections to public health. Although there is a rich literature describing these behaviors from nearly every culture around the world, there is a dearth of English language literature reporting these behaviors in Japan and Korea. Here, we systematically reviewed the medical evidence of pica in Korean and Japanese language journals to confirm their presence in these cultures and to characterize culturally-specific factors associated with these behaviors. We used Ichusi-Web and KoreaMed with a broad variety of recombined search terms including “pica,” “geophagy,” “amylophagy,” and “trichobezoar” in Korean and Japanese characters. Our results confirm that pica is present in both of these cultures, with particularly frequent reports of trichobezoar (the consumption of human hair).
Adaptive Noise Subspace Estimation Algorithm Suitable for VLSI Implementation

Field: Computer Science (Physical Sciences)

The aim of this letter is twofold: 1) to stabilize a fast adaptive noise subspace algorithm, which was proposed earlier in the literature under the name of FRANS algorithm and 2) to present a low computational cost version that is free from any square root and division operations, which is very suitable for VLSI implementation. A stability analysis and simulation results are also given in order to assess the performance of this algorithm.
Herbal remedies used for the management of urolithiasis in Abbottabad, Northern Pakistan

Field: Medicine (Health Sciences)

The current study was performed to evaluate the ethnobotanical uses of medicinal plants to treat and prevent kidney diseases, especially urolithiasis in the Abbottabad region, Northern Pakistan. Field surveys were conducted from 2014–2016 in various rural and tribally dwelled hilly areas like Ayubia National Park, Sherwan and Thandiani. Ethnobotanical information about the medicinal plants employed to treat urinary ailments was obtained from well-informed sources like local healers (hakims) and residents (men/women), who had vast knowledge of local plants uses. The questionnaire method was adopted to record the information and queries were made to verify the information. Informed consent was obtained from each informant before conducting the interview process. Quantitative ethnobotanical indices were calculated for each recorded species. Correlation analysis between the RFC, UV and FL% was tested by Pearson’s correlation, SPSS (ver. 16). A total of 38 plant species belonging to 27 families were being used in the study area to treat Urolithiasis or kidney stone diseases. Asteraceae was the most dominant family with 5 species. Local people used different methods of preparation for different plant parts; among them, decoction was the popular and dominant way of preparation (52.6%), followed by powder (18.4%), extracts (15.7%), juice (7.8%) and cooked (5.2%). The highest UV was recorded for Rumex acetosa L. (1.14) followed by Agrimonia eupatoria L. (1.1), Equisetum ramosissimum Desf. (1.05), Aerva lanata L. (1.04), Eclipta alba Hassak. (1.03). Moreover, twenty-three species were recoded with above 50% Fidelity level. It was found that most of the plant species (16 species) were explicitly used to remove kidney stones. All the obtained data about the ethnomedicinal uses of plants to treat urinary tract ailments are alphabetically categorized to their botanical name/family, local name, phytoconstituents, dosage and route of administration, along with quantitative indices value. All the collected ethnomedicinal plants require a thorough scientific investigation for isolation, identification, biochemical assays, toxicities and evaluation of pharmacological activities of the phytoconstituents, especially of the plants recorded with a high-fidelity level before their usage in clinics.
Choreography as seen through the lens of photography. Time in composition: Rainer, Paxton and Charmatz

Field: Arts and Humanities (Social Sciences)

Amongst the different uses of photography for and by dance, what it is important to unravel each time is as much the (strategy of) capturing the body in motion through photography, as the way in which dance itself understands photography. The way in which it appropriates it, integrates it into its processes or else uses it for a specific outcome (artistic, documentary), but also very simply the way in which the dancers or choreographers conceive of it, grasp it. What do they mean by “photography”? What does the term “pho­tography” cover in their discussions and what status do they give it in their choreographic practices? We shall see that what is involved is just as much the image (a concrete photographic image, the medium or subject of creation), as an idea about photography. The issue here is thus more like what Rosalind Krauss calls “the photographic” that is to say, photography as a theoretical subject, from which a new horizon of interrogation (aesthetic, historical, semiotic…) opens up. When applied to the field of dance composition, “photography” thus becomes a pretext for a reflection on time. Indeed, the intrusion of photography and the photographic into the field of choreography results, in particular, in an investigation on the temporality of movement and its relationship to fluidity.
A Metacognitive Approach to Phonics

Field: Social Sciences (Social Sciences)

For poor readers, one roadblock to the construction of meaning from text may be the inability to decode words quickly and accurately. In most cases more phonics instruction, similar to what has not worked in the past, does not improve this situation. Based on an analysis of the research literature in decoding and linguistics and a 4-year cycle of program development, a new program was created for teaching decoding to poor readers of average or above intelligence in grades 1 through 8. The program guides students to become aware of patterns and consistencies in our language and to apply a decoding process of using what they have learned about words to decode words they do not know. It is a teacher directed, supplemental program to be taught to a whole class for approximately 15 to 20 minutes a day and is intended to be used in conjunction with a basal reader or trade book program. The program features a multisensory approach, strong emphasis on vocabulary and language development, and a direct teaching model. Goals of the program include teaching students to use known words to decode unknown words, to discriminate structural components of words, to see how our language is organized, to be flexible in pronouncing words, and to demonstrate automaticity in decoding---all as foundation blocks for the meaning-making process. Preliminary evidence suggests that the program has been successful in improving students' decoding skills.
Modelling of microwave magnetoelectric effect in a laminate of ferrite and piezoelectric bimorphs

Field: Physics and Astronomy (Physical Sciences)

Abstract The article discusses the magnetoelectric (ME) effect in a layered structure of ferrite and two piezoelectric bimorphs. Proposed theoretical model predicts a giant microwave ME coupling at the coincidence of high-order harmonics of electromechanical resonance and ferromagnetic resonance for the ferrite. In such structures, ME interaction is known to be a result of mechanical strains. Using two piezoelectric bimorphs results in the excitation of high-order harmonic modes that are suppressed in ferrite-piezoelectric bilayers. ME coefficient of 300 V/(cm·Oe) at 5 GHz is predicted for the fifth resonance mode in the laminate of yttrium-iron garnet and two langatate bimorphs. The phenomenon can be used for the realization of ME interaction based microwave devices.
In-Situ Formation of NiFe-MOF on Nickel Foam as a Self-Supporting Electrode for Flexible Electrochemical Sensing and Energy Conversion

Field: Materials Science (Physical Sciences)

Ni- and Fe-based metal-organic frameworks (NiFe-MOFs) have abundant valence states and have the potential to be used as bifunctional electrode materials. However, unannealed NiFe-MOFs are still not widely used in electrode materials, including electrochemical sensing, supercapacitors, and overall water splitting. In addition, the direct growth of active material on a conductive carrier has been developed as a binder-free strategy for electrode preparation. This strategy avoids the use of insulating binders and additional electrode treatments, simplifies the preparation process of the NiFe-MOFs, and improves the conductivity and mechanical stability of the electrode. Therefore, in this study, we employed a simple solvothermal method combined with an in situ growth technique to directly grow NiFe-MOF-X (X = 4, 8, 12) nanomaterials of different sizes and morphologies on nickel foam at low reaction temperatures and different reaction times. The NiFe-MOF-8 electrode exhibited high capacitive properties, with an area-specific capacitance of 5964 mF cm−2 at 2 mA cm−2 and excellent durability. On the other hand, NiFe-MOF-12 exhibited strong catalytic activity in electrocatalytic tests performed in a 1 M KOH aqueous solution, demonstrating hydrogen evolution reaction (η10 = 150 mV) and oxygen evolution reaction (η50 = 362 mV) activities. The electrochemical sensing tests demonstrated a good response to BPA. Overall, our results suggest that the direct growth of NiFe-MOFs on nickel foam using a simple solvothermal method combined with an in situ growth technique is a promising strategy.
Tone-change and tone-shift in White Miao

Field: Arts and Humanities (Social Sciences)

‘Tone’, at least in the literature dealing with Far Eastern languages, is commonly used in several ways: for instance, in ‘the tones of the language’, or ‘Cantonese has seven tones’, reference is made to the tones as membersof a system, while in ‘such-and-such a word has tone X’ the reference is tothe assignment of an item to one of the members of the system. The differencein reference is made quite clear by the context, and no ambiguity ensues; theconcept of ‘tone’ remains precise, and difficulties arise only when no distinctionis made between ‘tone’ as used above and the realization of tones in particularenvironments. Far different is the use of expressions denoting ‘changes intone’, for which there is no agreed terminology. In diachronic work, ‘change’ usually refers to changes through time in the overall system of basic tones, and secondarily to changes in the assignment of items to members of this system, as, for instance, when it is said that in Standard Chinese, items with voicedplosive initials changed from the shăng tone to the qù tone by the Sung dynasty.
GmLac55 Enhanced Soybean Resistance Against Soybean Cyst Nematodes Through Lignin Biosynthesis

Field: Agricultural and Biological Sciences (Life Sciences)

Soybean cyst nematodes (SCNs) are a significant disease that causes yield loss and reducing seed quality in soybeans (Glycine max). Developing SCN-resistant soybean varieties can minimize the need for insecticide use and reduce yield loss. Cinnamate-4-hydroxylase (C4H) and laccase (Lac) are key enzymes in the lignin synthesis pathway. In this study, SCN stress significantly promoted lignin accumulation in soybean roots and upregulated the expression of lignin signaling pathway genes GmC4H (Glyma.02G236500), GmLac55 (Glyma.13G076900), and GmLac85 (Glyma.20G051900). Using Agrobacterium rhizogenes-mediated transformation, the pNI900 expression vector was introduced into the soybean cultivar Williams 82 to generate GmLac55-overexpressing plants. The overexpression of GmLac55 enhanced soybean roots resistance to SCN and inhibited the further development of J2 larvae. Our study presents a strategy for increasing SCN resistance in soybean through Agrobacterium-mediated targeted mutagenesis of the GmLac55 gene.
Effects of Minor Alloying Elements on Inherent Creep Strength Properties of Ferritic Steels

Field: Materials Science (Physical Sciences)

Creep rupture strength properties of carbon steel have been analyzed from a viewpoint of inherent creep strength, andthe effects of minor alloying elements on inherent creep strength have been investigated. Inherent creep strength, which is a new concept proposed by the authors, is an essential strength property independent of both microstructural morphology and time, and the governing factor of long-term creep strength property. Large heat-to-heat variation of inherent creep strength observed for the carbon steel has been cleared to be caused by a remarkable improving effect of Mo on that. However, strengthening effect of Mo has been speculated to saturate at a slight amounts of about 0.03mass%. It has been concluded that an inherent creep strength of ferritic steel is governed by solid solution strengthening effect due to such as C and Mo, and the maximum inherent creep strength is obtained by the addition of C and about 0.03mass% of Mo. Moreover, it has been suggested that the inherent creep strength of many ferritic heat resistant steels are maximum level for ferritic steels, consequently, creep rupture strength of those converges to an almost same level at the long-term region.
Multiplex PCR Assay for Rapid Detection and Genotyping of Helicobacter pylori Directly from Biopsy Specimens

Field: Medicine (Health Sciences)

ABSTRACT We developed and evaluated a simple, novel multiplex PCR assay for rapid detection of Helicobacter pylori infection and for the determination of vacA and cagA genotypes directly from gastric biopsy specimens. This assay did not require culturing of strains or extraction of DNA from biopsy samples. This multiplex PCR assay would be of particularly great value for laboratories in developing countries.
Activity and characterization of anion-modified iron(III) oxides as catalysts for direct liquefaction of low pyrite coals

Field: Chemical Engineering (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTActivity and characterization of anion-modified iron(III) oxides as catalysts for direct liquefaction of low pyrite coalsV. R. Pradhan, J. Hu, J. W. Tierney, and I. WenderCite this: Energy Fuels 1993, 7, 4, 446–454Publication Date (Print):July 1, 1993Publication History Published online1 May 2002Published inissue 1 July 1993https://pubs.acs.org/doi/10.1021/ef00040a002https://doi.org/10.1021/ef00040a002research-articleACS PublicationsRequest reuse permissionsArticle Views145Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effect of pharyngeal water stimulation on esophageal peristalsis and bolus transport

Field: Medicine (Health Sciences)

Sensory stimuli originating from the pharynx inhibit esophageal peristalsis induced by a dry swallow. Our aims were to determine the effect of these stimuli on esophageal bolus transport and esophageal peristalsis induced by swallowing different volumes of liquid and semisolid boluses. We studied nine healthy volunteers age 35 +/- 4 yr in the supine position by intraluminal esophageal manometry as well as concurrent videofluoroscopy and manometry. In all subjects progression of peristalsis induced by swallowing of different volumes of water and mashed potato boluses was inhibited at all sites by pharyngeal water injection. Threshold volume for inhibition of the peristalsis induced by swallows of 5 and 10 ml of water was similar but significantly higher compared with dry swallows (P < 0.05). Pharyngeal water injection invariably halted transit of the barium boluses through the esophagus. Sensory impulses originating from the pharynx 1) inhibit esophageal bolus transit and 2) are capable of overcoming the facilitating effect of a liquid bolus on the swallowing apparatus. This phenomenon may explain the mechanism of some of the failed esophageal peristalsis observed in clinical practice.
Liberal theory

Field: Social Sciences (Social Sciences)

This chapter examines a political theory of international constitutionalism that is most associated with one self-identifying ‘liberal’, Gilford John Ikenberry. While Ikenberry’s name is synonymous with this theory, he is perhaps best recognised as the intellectual who has done the most to articulate its principles and aspirations from within American political society. Indeed, it is argued here, this theory is inextricably American in that it is born of liberal worldview in American political and constitutional thought, and it receives its full expression as a crisis-prone account of the dilemma to constituting a stable and liberal international order from reflections on the American and state-bound experience of war in the twenty-first century.
Prognostic Value of Endogenous and Exogenous Metabolites in Liver Transplantation

Field: Medicine (Health Sciences)

Liver transplantation has been widely accepted as an effective intervention for end-stage liver diseases and early hepatocellular carcinomas. However, a variety of postoperative complications and adverse reactions have baffled medical staff and patients. Currently, transplantation monitoring relies primarily on nonspecific biochemical tests, whereas diagnosis of multiple complications depends on invasive pathological examination. Therefore, a noninvasive monitoring method with high selectivity and specificity is desperately needed. This review summarized the potential of endogenous small-molecule metabolites as biomarkers for assessing graft function, ischemia-reperfusion injury and liver rejection. Exogenous metabolites, mainly those immunosuppressive agents with high intra- and inter-individual variability, were also discussed for transplantation monitoring.