jimnoneill/paper-to-field-training huggingface dataset:
Return and Volatility Spillovers Between the US, Japanese and Malaysian Stock Markets

Field: Economics, Econometrics and Finance (Social Sciences)

The present study investigates the return and volatility spillover between the stock markets of the US, Japan and Malaysia using weekly data concerning the S&P 500, NIKKEI 225 and KLCI composite indices from January 1990 to May 2013. Employing a cross-correlation function method, the results show that a unidirectional causality-in-mean exists from the stock markets of the US and Japan to the Malaysian stock market. Malaysian stock returns immediately react to the shocks received from the stock markets of the US and Japan and the reaction continues for 12 weeks. The causality-in-variance test shows that the volatility of the Malaysian stock market is more affected by the US stock market than the Japanese stock market. Similarly, the variance-causality test shows that the speed of variance spillover from the US stock market to the Malaysian stock market is high; and is significant from the first week. The results from the present study are relevant for fund managers and investors when making investment decisions that involve the consideration of risk and return elements; for policy makers to monitor the financial market stability; and for hedgers to forecast risk and develop hedging strategies. Keywords: Causality in mean; causality in variance; spillovers; stock market volatility; structural break in variance ABSTRAK Kertas ini mengkaji limpahan pulangan dan volatiliti antara pasaran saham Amerika Syarikat, Jepun dan Malaysia menggunakan data mingguan indeks komposit S&P 500, NIKKEI 225 dan Indeks Komposit Kuala Lumpur (KLCI) bagi Januari 1990 hingga Mei 2013. Melalui kaedah fungsian korelasi bersilang, hasil kajian mendapati wujudnya hubungan satu arah sebab akibat dalam min pulangan saham dari Amerika Syarikat dan Jepun terhadap pulangan saham Malaysia. Pulangan saham Malaysia menunjukkan reaksi segera terhadap kejutan dari Amerika Syarikat dan Jepun dan reaksi tersebut berlarutan sehingga 12 minggu. Hasil ujian sebab akibat dalam varians pula mendapati volatiliti pasaran Malaysia lebih dipengaruhi oleh Amerika berbanding Jepun. Begitu juga daripada hasil ujian sebab akibat dalam varians yang menunjukkan kesan signifikan bermula dari minggu satu bermakna limpahan varians dari pasaran Amerika Syarikat terhadap Malaysia adalah lebih laju. Hasil kajian ini relevan kepada pengurus dana dan pelabur dalam pembuatan keputusan pelaburan aset kewangan yang mementingkan pulangan dan risiko; pembuat polisi dalam mengawal kestabilan pasaran kewangan dan pelindungnilai dalam meramal risiko dan membentuk strategi lindungnilai. Kata kunci: Hubungan sebab akibat dalam min; hubungan sebab akibat dalam varians; limpahan pasaran saham volatiliti; perubahan struktur dalam varian
Pathophysiology of Common Hemolytic Syndromes

Field: Medicine (Health Sciences)

With increased understanding of the inherited disorders of red cell metabolism, the physician can diagnose hemolytic anemia in a logical fashion. The pathophysiologic aspects of the major categories of hemolysis are discussed here, with attention focused on pyruvate kinase deficiency and glucose-6-phosphate dehydrogenase deficiency. The former is uncommon but highly instructive. The latter is extremely common and equally instructive, and must be carefully searched for in patients who may be the helpless victims of enthusiastic therapy.
Integrating Civility into the Classroom: Practicing and Teaching Civility to Prepare Students for Career Success

Field: Social Sciences (Social Sciences)

Abstract Integrating Civility into the Classroom: Practicing and Teaching Civility to Prepare Students for Career Success The focus of most engineering and technology programs is to provide students with the technical skills required for success in their future careers. Often overlooked, but equally important for career success, is training on the “soft skills.” In particular, faculty need to integrate the practice and teaching of civility into their courses. The far-reaching benefits of civility cannot be overstated. Civility can help to resolve many challenges in academia, the workplace and society. From overcoming bullying and discrimination, to promoting diversity and improving interpersonal relationships. A growing civility movement is currently being undertaken at several levels; local, national and international. Civility is also impacting various institutions, including high schools, government and some workplaces. University faculty can further this movement by practicing classroom civility and incorporating the teaching of civility to their students. An understanding of civility can provide students with the social skills necessary for career success. Faculty need to reevaluate traditional teaching approaches in order to integrate multidisciplinary learning into their courses. Through civility education, teachers can help students to recognize the life-long benefits civility can have on their future success. In the paper the author will describe how he practices classroom civility and integrates the teaching of civility into his subjects. The paper will identify the benefits of civility and why it’s important for students to learn about civility. Also the paper will provide ideas for engineering and technology faculty on how they can incorporate civility concepts into their subjects and classroom management.
Dalmutladdo plant macrofossil dataset

Field: Earth and Planetary Sciences (Physical Sciences)

Raw data for the Dalmutladdo plant macrofossil dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
ChemInform Abstract: Selenium‐Containing Heterocycles from Isoselenocyanates: 4‐Methylselenazole Derivatives from the Reaction with Malononitrile and Propargyl Chloride.

Field: Chemistry (Physical Sciences)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Non‐invasive prediction of fetal growth restriction by whole‐genome promoter profiling of maternal plasma DNA: a nested case–control study

Field: Medicine (Health Sciences)

Objective To predict fetal growth restriction (FGR) by whole‐genome promoter profiling of maternal plasma. Design Nested case–control study. Setting Hospital‐based. Population or Sample 810 pregnancies: 162 FGR cases and 648 controls. Methods We identified gene promoters with a nucleosome footprint that differed between FGR cases and controls based on maternal plasma cell‐free DNA (cfDNA) nucleosome profiling. Optimal classifiers were developed using support vector machine (SVM) and logistic regression (LR) models. Main outcome measures Genes with differential coverages in promoter regions through the low‐coverage whole‐genome sequencing data analysis among FGR cases and controls. Receiver operating characteristic (ROC) analysis (area under the curve [AUC], accuracy, sensitivity and specificity) was used to evaluate the performance of classifiers. Results Through the low‐coverage whole‐genome sequencing data analysis of FGR cases and controls, genes with significantly differential DNA coverage at promoter regions (−1000 to +1000 bp of transcription start sites) were identified. The non‐invasive ‘FGR classifier 1’ (C FGR 1) had the highest classification performance (AUC, 0.803; 95% CI 0.767–0.839; accuracy, 83.2%) was developed based on 14 genes with differential promoter coverage using a support vector machine. Conclusions A promising FGR prediction method was successfully developed for assessing the risk of FGR at an early gestational age based on maternal plasma cfDNA nucleosome profiling. Tweetable abstract A promising FGR prediction method was successfully developed, based on maternal plasma cfDNA nucleosome profiling.
RISK MANAGEMENT IN LIFE INSURANCE COMPANIES IN BOSNIA AND HERZEGOVINA

Field: Business, Management and Accounting (Social Sciences)

Despite the global economic crisis, life insurances in BiH are being in positive trend and their number rises. The paper is aimed to analyze the degree of development of risk management systems in life insurance companies in BiH. In particular, the authors have tried to establish the existence of policies and procedures in the framework of risk management in life insurance companies. Also, the most common risks identified by insurance companies are the following: liquidity risk, risk of change in price of financial real and other assets, and foreign exchange risk. The authors will analyze the most common methods that insurance companies use to protect themselves. The authors also seek to identify limitations in development of risk insurance system.
Vibrational and Photoelectron Investigation of Amorphous Fluorinated Carbon Films

Field: Chemistry (Physical Sciences)

sp/sp2 amorphous carbon mixtures have been deposited by pulsed jet cooled supersonic carbon beams using graphite and polytetrafluoroethylene (PTFE) as target materials in a pulsed laser vaporization source. The investigated structure and composition reveal the formation of hydrogenated and fluorinated carbons, with the latter embedded in a PTFE-like matrix. There is a relevant structural difference between the two classes of samples in both the sp and sp2 subsystems, but a similar behavior in the degradation kinetics performed by dry air exposure was observed by Raman spectroscopy. Kinetic results are discussed with relation to the separate degradation of double- and triple-bonded carbon sp chains in the films.
Prognostic role of thymidylate synthase (TS) gene polymorphisms in gastric cancer patients treated with surgery and adjuvant chemotherapy

Field: Medicine (Health Sciences)

4044 Background: Previous studies suggest that TS expression in tumor tissue is related with both sensitivity to 5-FU-based chemotherapy and patients’outcome. TS gene has polymorphic sequences in its untranslated region (UTR) which are associated with TS expression. Aim of this study is to evaluate prognostic role of the TS polymorphisms in gastric cancer patients treated with surgery and 5-FU-based adjuvant chemotherapy. Methods: Ninety patients with advanced gastric cancer who had undergone radical surgery and received 5-FU-based adjuvant chemotherapy were included in this study. All patients underwent a 44-months minimum follow-up time. Lymphocyte genomic DNA was extracted from peripheral blood samples of the patients. Genotypes of variable number of tandem repeat (VNTR) and G/C single nucleotide polymorphism (SNP) in the TS 5’-UTR and 6bp deletion polymorphism in the 3’-UTR were determined by PCR and PCR-RFLP. According to previous studies the VNTR and the SNP were combined and the genotypes were grouped as follows; 5’-high (3G/3G, 3G/3C, 2R/3G) and 5’-low (2R/2R, 2R/3C, 3C/3C). Genotypes in 3’-UTR were also classified as follows; 3’-high (ins6/ins6) and 3’-low (del6/ins6, del6/del6). Results: There were no significant relationships between clinico-pathologic features and each TS polymorphism. Ten patients were 5’-high/3’-high (100% relapse/death), 36 patients were 5’-high/3’-low (67% relapse/death, 33% disease-free), 19 patients were 5’-low/3’-high (58% relapse/death, 42% disease-free), 25 patients were 5’-low/3’-low (36% relapse/death, 64% disease-free). Patients with 5’-low/3’-low genotypes showed significantly better outcome than those with 5’-high/3’-low and 5’-high/3’-high genotypes in regard to both 3-year disease-free and overall survival rates. The presence of at least one high TS expression genotype showed independent adverse prognostic role in multivariate analysis. Conclusions: TS polymorphisms showed prognostic influence in the studied population of gastric cancer patients. Analysis of combined TS5’- and TS3’-UTR genotypes may be useful for improving adjuvant treatment strategies with tailored chemotherapy. No significant financial relationships to disclose.
Radioisotope-ADME studies of Trastuzumab-monomethyl auristatin F in tumor bearing mice and healthy marmosets

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Radioisotope ADME (RI-ADME) studies are enabling visualization of the biodistribution in molecular imaging. We applied RI-ADME to investigate the tumor targeting capacity and biodistribution of trastuzumab-monomethyl auristatin F (LCB14-0110) in JIMT-1 xenograft mice and healthy marmoset. The LCB14-0110 was labelled with 125I. 125I-LCB14-0110 was intravenously administered to the animals. The gamma-count and single-photon emission computed tomography/computed tomography (SPECT/CT) was conducted for biodistributioon and bioimaging of the biopharmaceutics. Tumor uptake in xenograft mice was highest at three-day after 125I-LCB14-0110 administration in both the biodistribution and SPECT/CT bioimaging. Alternatively, blood and organ tissues showed gradual decrease in radioactivity over time. In marmosets, radioactivity in all organ tissues rapidly reduced and no specific targeting of organs was observed in the biodistribution study and SPECT/CT imaging. Hence, 125I-LCB14-0110 demonstrated effective tumor targeting capacity and accumulated in JIMT-1 cell-bearing mice. However, accumulation did not occur in the organs of xenograft mice. Additionally, marmosets showed rapidly decrease in radioactivity throughout the entire body without accumulation in the normal organs. We also confirmed that the drug distribution was similar in normal organs between the two experimental animal species except spleen. Therefore, 125I is expected to be a useful tool in the study of RI-ADME in biopharmaceuticals through minimal antibody modification.
Modification of Quantum Measurements by Mapping onto Quantum States and Classical Outcomes

Field: Physics and Astronomy (Physical Sciences)

We consider a quantum-classical (q-c) channel associated with quantum observable and a function on the set of results which defines a subordinate observable. We describe this situation as a combination of two quantum channels, where the output of the first channel is the classical outcome of the subordinate observable and quantum state which can be measured to yield the measurement result of the original channel. We also show that, under certain conditions, the states after the first channel in the given decomposition provide better quantum properties than the classical output of the original q-c channel.
Quality in health care

Field: Health Professions (Health Sciences)

For decades, the health care industry in Serbia has been operating in its own domain of economic rules, ignoring external factors such as competition. As competition intensifies, healthcare institution become more aware of acute need to cap rising operating costs and meet (or even exceed) a higher level of expected patient care quality. The performance of health care system depends on certain performance attributes, among them the quality of care is most important. In the paper the quality of health care is considered by Deming quality circle and the most commonly used quality dimensions. Also a model for quality assessment of processes/services in a health care institution is proposed.
Sentiment Classification of User Reviews for KAI Access Application Using Naive Bayes Method

Field: Computer Science (Physical Sciences)

KAI Access is a train ticket booking application that offers convenience and various features for its users. However, the app has received a low rating of 2.4 out of 5 stars on the Play Store, indicating user dissatisfaction. This study conducts a quantitative sentiment analysis of the KAI Access application based on user sentiments expressed on Twitter. Using the CRISP-DM method, data were collected from Twitter with the Tweepy tool, amassing around 4,000 tweets from June to August 2023. The data underwent a preprocessing stage to ensure the quality and accuracy of the analysis. This stage involved removing duplicate tweets, eliminating retweets, and filtering out emoticons and other non-text elements. In the modeling stage, the Multinomial Naive Bayes Classifier algorithm was employed, achieving an accuracy rate of 84.6%. The model performed better at identifying negative reviews, with a precision of 0.96, recall of 0.86, and an F1-score of 0.91. In contrast, the identification of positive reviews was less effective, with a precision of 0.41, recall of 0.75, and an F1-score of 0.53. These findings shed light on the low ratings for KAI Access, particularly in the context of user reviews. The results of this study provide further understanding regarding the low rating given to KAI Access, particularly in the context of user reviews. By using this classification system, it is hoped that developers can design more specific improvements to enhance the user experience, especially in handling positive reviews which have the potential for performance improvement.
Empty Proper Names: Semantic and Epistemological Issues

Field: Arts and Humanities (Social Sciences)

Millianism is a semantic theory investigating reference-based meaning. Since proper names contribute just their referents to the propositions expressed, empty names pose problems for this approach. The paper suggests that Millianism has to admit that empty names are meaningless. So, empty names semantically differ from non-empty ones. However, Millianism may admit that, in communication, empty names and non-empty ones behave similarly. We argue that proper names, including empty ones, prompt one to create mental surrogates for individuals, if any, they are supposed to represent. The mental surrogates are called pure individuators because they identify individuals in a non-qualitative manner and distinguish objects from each other as merely numerically distinct. Pure individuators serve also as grounds for gathering information about individuals represented by them. We investigate how pure individuators work and guide our communication.
Plano del puerto y ciudad de Denia situado el casto. en la latitud N. de 38°. 50'. 40". y en la long. de 6°. 22'. 27". al E de Cadiz.

Field: Earth and Planetary Sciences (Physical Sciences)

Nautical chart representing the port and city of Dénia, Spain, situated in relation to the Castle of Dénia. Shows islands, roads, cities, castle, topography, vegetation, coastline, bays, ports and depths, given in six Castillian feet. Relief shown with hachures and shading. Includes latitudinal and longitudinal coordinates, a compass rose with north oriented toward bottom right of sheet, as well as a bar scale given in maritime miles. With explanatory note and index indicating the type of sea floor, such as sand or rocks. Black and white engraving. Chart is 24 x 30 cm, on sheet 29 x 40 cm.
Treatment of ocular surface squamous neoplasia with topical 1% 5-fluorouracil

Field: Medicine (Health Sciences)

Ocular surface squamous neoplasia (OSSN) is the most common type of ocular tumour. An eighty-year-old man with an elevated lesion in the right eye was diagnosed to have OSSN. 1% topical 5-FU was started as an intermittent treatment. Examination during each visit showed consistent reduction in size of lesion. The patient showed complete regression with no recurrence following treatment with 1% 5-FU at 3 months from presentation. Tropical treatment with 1% 5-FU provides excellent prognosis in cases of OSSN.
Aspiration Pneumonia in Patients with Cleft Palate

Field: Medicine (Health Sciences)

Purpose: To assess the incidence of aspiration pneumonia in infants with cleft palate and to compare the incidence between complete and incomplete types of cleft palate. Materials and Methods: A review of medical records revealed 100 infants who had undergone initial surgery to repair cleft palate in our hospital during a recent three-year period. Aspiration pneumonia was defined as the coexistence of pneumonia at chest radiography with a history of frequent choking during feeding. The anatomic distribution of aspiration pneumonia was analyzed, and the incidences of aspiration pneumonia in infants with complete and incomplete cleft palate were compared. Results: Among 100 children, aspiration pneumonia was found in 35 (35%). Those with complete and incomplete cleft palate showed similar incidences of the condition (27 of 70 [39%] vs 8 of 30 [27%], p=0.36). Pneumonia was most commonly seen in the left lower lobe (11 of 35), followed by the right upper and lower lobes. Conclusion: Aspiration pneumonia is frequently associated with infants with cleft palate. There is no statistical difference in the incidence of aspiration pneumonia between the complete and the incomplete cleft palate group.
Rootstock-scion signalling: key factors mediating scion performance.

Field: Agricultural and Biological Sciences (Life Sciences)

Although the scion genotype often has a dominant effect on most agronomic traits, the rootstock introduces new sources of genotypic and phenotypic variability in the crop, due to rootstock×scion×environment interactions. These interactions are essentially based on hydraulic and chemical signals through the xylem (root to shoot) and the phloem (shoot to root). Although maximizing crop yield depends on the leaves receiving an optimal supply of water and mineral nutrients from the root system via the xylem, integrated plasticity involves long-distance communication, where small organic molecules play key roles. Except for some chlorophyll- and photosynthesis-related compounds, roots are believed to produce every type of compound that exists in plants (Gregory, 2006). Although many recent reviews have focused on specific chemical compounds in root-to-shoot communication, mainly phytohormones, other small molecules in xylem sap can modulate whole-plant processes and/or stress responses. Progress in identifying the roles of various signals in regulating root-to-shoot communication may be slow because at least four kinds of signals allow roots to influence shoots: (i) increased root export of an existing signalling compound or generating a new one; (ii) decreased root export of an existing signalling compound; (iii) accumulation of signal/message in the shoot (source) due to reduced demand in the root; and (iv) a reduction in signalling compounds in the shoot due to increased root demand. While this conceptual framework conveniently discriminates root-to-shoot (xylem sap composition: (i) and (ii)) and shoot-to-root (phloem sap composition: (iii) and (iv)), many signalling molecules can be synthesized in both root and shoot tissues and can travel in both xylem and phloem saps. This is recognized in empirical flow models, which have been applied to determine uptake, synthesis, transport and metabolism of signalling molecules. This chapter examines ionic, phytohormonal, proteomic and RNA signalling in planta, highlighting specific examples of signalling between the scion and rootstock. We draw attention to examples of grafting between specific combinations of scions and rootstocks that are deficient in (or overexpress) these signals, thus highlighting their importance (or otherwise) in regulating plant responses.