jimnoneill/paper-to-field-training huggingface dataset:
Designing an IT Risk Management Ontology grounded on Systematic Literature Review

Field: Computer Science (Physical Sciences)

Organizations that operate digital-based services rely heavily on Information Technology (IT). Nonetheless, this IT dependency inducts risks that could impact the achievement of organizations goals and even its own survival. One usual solution is to enforce an IT Risk Management (RM) approach to cope with IT-related risks. However, due to IT RM complexity and diversity, many organizations are not able to implement it successfully. Therefore, an IT RM ontology capturing the essential of IT RM concepts and its relations constitute a positive step towards the simplification and clarification of IT RM, which by its turn facilitates the IT RM enforcement. This paper designs an IT RM ontology, using DEMO, that is grounded in a SLR that follows the Kitchenham (2004) guidelines. The objective is to prescribe what key concepts, relationships and processes should be enforced to reduce the IT RM implementation effort when compared with an implementation from scratch.
Perishable Product Inventory Management In The Case Of Discount Policies And Price-Sensitive Demand: Discrete Time Simulation And Sensitivity Analysis

Field: Decision Sciences (Social Sciences)

In B2C contexts, the demand is normally shifted towards products with higher residual shelf life (LEFO issuing policy). In such contexts, the risk is that products closer to the expiration date could not be picked up by consumers, thus reaching the end of their shelf life unsold, with the need to be disposed of. To reduce the extent of this phenomenon, retailers can promote the sale of expiring products by introducing appropriate discount policies. In this paper, a multi-period discrete-time simulation model is developed considering perishable products, having a fixed and deterministic shelf life, issued according to a periodic review policy. A mixed LEFO-FEFO issuing policy was considered. Specifically, in the absence of discount policies, the demand is fulfilled according to LEFO logic. When a discount policy is applied, a portion of the demand, proportional to the discount, shifts to discounted expiring products and is handled according to FEFO logic. The discount policy was defined as a percentage discount, applied to products with a residual shelf life of less than a defined number of days. The presented model was applied to a specific case study and a sensitivity analysis was performed to assess the impact of both the discount policy and other contour variables, such as demand parameters (mean and standard deviation), lead time (LT) and product shelf life (SL), on average daily profit (P). The results show that, for the context analysed, the introduction of a proper discount policy leads to an increase in P of between 0.31% and 2.45%. Moreover, it was obtained that demand variability positively affects the impact of discount policies. Sensitivity analysis finally showed that P is negatively correlated with LT and positively correlated with SL.
Combinatorial structure of colored HOMFLY-PT polynomials for torus knots

Field: Mathematics (Physical Sciences)

We rewrite the (extended) Ooguri–Vafa partition function for colored HOMFLY-PT polynomials for torus knots in terms of the free-fermion (semi-infinite wedge) formalism, making it very similar to the generating function for double Hurwitz numbers. This allows us to conjecture the combinatorial meaning of full expansion of the correlation differentials obtained via the topological recursion on the Brini–Eynard–Mariño spectral curve for the colored HOMFLY-PT polynomials of torus knots. This correspondence suggests a structural combinatorial result for the extended Ooguri–Vafa partition function. Namely, its coefficients should have a quasi-polynomial behavior, where nonpolynomial factors are given by the Jacobi polynomials (treated as functions of their parameters in which they are indeed nonpolynomial). We prove this quasi-polynomiality in a purely combinatorial way. In addition to that, we show that the (0,1) - and (0,2)-functions on the corresponding spectral curve are in agreement with the extension of the colored HOMFLY-PT polynomials data, and we prove the quantum spectral curve equation for a natural wave function obtained from the extended Ooguri–Vafa partition function.
beta-O-thalassemia from Algeria: genetic and molecular characterization

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract beta-Thalassemia is a major public health problem in Algeria. During a survey, a family including two cases of betaO-thalassemia was studied. The family study indicated that two of the affected siblings had homozygous beta-thalassemia; there were also both normal and heterozygous siblings, and both parents had beta-thalassemia trait. In the two cases of betaO-thalassemia there was no hemoglobin A in the peripheral blood, and no beta-globin chain synthesis in whole cell incubations. Hybridization of purified complementary DNA specific for alpha- and beta-globin messenger RNAs demonstrated less than 1% mRNAbeta relative to mRNAalpha in circulating reticulocytes, and for one case in total RNA from bone marrow. There is no apparent beta- globin gene deletion as determined by hybridization in globin cDNAbeta sequence excess. Therefore the Algerian cases studied are similar in molecular pathology to some Southern Italian and Asian cases described previously, and differ from other Italian and Chinese betaO- thalassemias, in which hybridizable mRNAbeta has been demonstrated, and from deltabetaO-thalassemia, which is caused by a gene deletion.
Acute Ischemic Stroke in Children Vs Young Adults

Field: Medicine (Health Sciences)

Clinical characteristics, stroke etiology, and outcome (modified Rankin scale [0-6] score at 3-6 months) in children (1 month-16 years) and young adults (16-45 years) with arterial ischemic stroke (AIS) were compared in a multicenter study at University of Bern and other centers in Switzerland.
Juvenile xanthogranuloma developing after treatment of Langerhans cell histiocytosis: case report and literature review.

Field: Medicine (Health Sciences)

The synchronous or metachronous development of Langerhans cell histiocytosis and non-Langerhans cell histiocytosis in the same patient is rare. To date, only seven cases of xanthogranulomas developing in young patients with a history of Langerhans cell histiocytosis and systemic therapy have been reported in the literature. As of yet, the pathogenesis and the clinical significance of this phenomenon are unclear. We report the case of a 3 year old boy who developed juvenile Xanthogranulomas on the forehead and right upper eye lid 1.5 years after systemic therapy for monosystemic Langerhans cell histiocytosis of the bone and complete disease remission.
Implementing Dialectical Behaviour Therapy: organizational pre-treatment

Field: Health Professions (Health Sciences)

Abstract Implementing change in organizational systems is challenging, and implementing a new psychotherapeutic approach is no different. A literature exists on issues in implementation across a wide range of domains (technological, healthcare, justice). However, little of it is utilized in endeavours to implement innovations in psychological treatments. This paper draws on the implementation literature and on the experiences of the British Isles DBT Training Team (BIDBT) in implementing Dialectical Behaviour Therapy (DBT) in mental healthcare systems in the UK over the last 13 years. This paper describes principles and strategies of ‘organizational pre-treatment’ as a necessary prerequisite to implementation.
Study on the mechanism of CD13 molecule on Treg cell immune suppression of non-small cell lung cancer patients

Field: Medicine (Health Sciences)

Objective To detect the expression of CD 13 molecule and CD4+CD25+FoxP3+Treg cells in NSCLC and control groups,in order to investigate the mechanism of CD 13 molecule on Treg cell immune suppression of NSCLC patients. Methods 160 cases of NSCLC patients from June2013 to May 2014 in our hospital were selected,and another 60 cases without NSCLC were selected as control group. The expression of CD 13 molecule and CD4+CD25+FoxP3+Treg cells in NSCLC and control groups were detected by RT-PCR and immunehistochemistry. Results The mRNA expression of CD 13 and CD4+CD25+FoxP3+in control group were significantly lower than that in the NSCLC group( P 0. 05). The expression of CD 13 protein in NSCLC group was significantly higher than that in control group. The positive expression rate of the control group were only 20. 0%( 12 /60),and increased to 81. 9%( 131 /160) in NSCLC group,the difference was statistically significant( P 0. 05). The expression level of CD4+CD25+FoxP3+Treg cells in NSCLC( 24. 1 ± 6. 3) was significantly higher than that in the control group( 0. 7 ± 2. 1,P 0. 05). Conclusion The CD13 molecule can reduce MHCⅡ epitope,thereby reducing the recognition ability of T cells to tumor cell,leading to no response or immune tolerance of tumor cell. This the possible main mechanism of CD 13 molecule on Treg cell immune suppression of non-small cell lung cancer patients.
Who Governs Southern Europe?

Field: Social Sciences (Social Sciences)

In modern politics, cabinet ministers are major actors in the arena of power as they occupy a strategic locus of command from which vital, authoritative decisions flow continuously. Who are these uppermost policy-makers? What are their background characteristics and credentials? How are they selected and which career paths do they travel in their ascent to power?This set of research issues has guided this collection, a comprehensive, empirical account of the composition and patterns of recruitment of ministerial elites in Southern Europe throughout the last 150 years, thus encompassing different historical circumstances and political settings - liberal, authoritarian and democratic. With original, comparative data from the 19th century to the present, it provides valuable material for debates about how regime change and economic development affect who governs. First published in 2003 by Frank Cass / Reprinted in 2012 by Routledge
Diagnostic and surveillance testing capability for mpox in the EU/EEA, September 2024

Field: Medicine (Health Sciences)

In response to the increasing number of mpox cases caused by monkeypox virus (MPXV) clade I in the African continent and the first reported travel-related clade Ib case of mpox in EU/EEA, the European Centre for Disease Prevention and Control surveyed national capability for detection and characterisation of MPXV in the EU/EEA. The results showed high level of capability for case confirmation by PCR, alongside molecular typing methods for identification of MPXV clades and/or clade I subclades within the EU/EEA.
A systematic review of criteria used to report complications in soft tissue and oncologic surgical clinical research studies in dogs and cats

Field: Veterinary (Health Sciences)

Abstract Objective To evaluate reporting of surgical complications and other adverse events in clinical research articles describing soft tissue and oncologic surgery in dogs and cats. Study design Systematic literature review. Sample English‐language articles describing soft tissue and oncologic surgeries in client‐owned dogs and cats published in peer‐reviewed journals from 2013 to 2016. Methods CAB, AGRICOLA, and MEDLINE databases were searched for eligible articles. Article characteristics relevant to complications were abstracted and summarized, including reported events, definitions, criteria used to classify events according to severity and time frame, and relevant citations. Results One hundred fifty‐one articles involving 10 522 animals were included. Canine retrospective case series of dogs predominated. Ninety‐two percent of articles mentioned complications in study results, but only 7.3% defined the term complication . Articles commonly described complications according to time frame and severity, but terminology and classification criteria were highly variable, conflicting between studies, or not provided. Most (58%) reported complications could have been graded with a published veterinary adverse event classification scheme, although common intraoperative complications were notable exceptions. Conclusion Definitions and criteria used to classify and report soft tissue and oncologic surgical complications are often absent, incomplete, or contradictory among studies. Clinical significance Lack of consistent terminology contributes to inadequate communication of important information about surgical complications. Standardization of terminology and consistency in severity scoring will improve comparative evaluation of clinical research results.
Response of the rat to saccharin with particular reference to the urinary bladder

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Male and female Wistar rats were administered sodium saccharin for life (2 yr) either in the drinking water or diet. The maximum palatable dose of saccharin in the drinking water was found to be 2 g/kg/day and, even then, there was some voluntary restriction of fluid intake in the males. By contrast, double this dose--namely 4 g/kg/day, was palatable in the diet. A control group of rats of both sexes received saccharin-free diet and drinking water. Mild urothelial hyperplasias developed from 85 weeks in rats of both sexes receiving saccharin either in the drinking water or diet; the incidence was statistically significant in both the bladders and kidneys of rats receiving the higher dose of saccharin in the diet, but in the kidneys only of rats receiving the lower dose of saccharin in the drinking water. Telangiectasia of the vasa recta was significant in saccharin-treated rats of both sexes at both doses. A very low incidence of bladder tumours, exclusively in males receiving the higher saccharin dose in the diet was seen from 95 weeks. No consistent relationship between bladder epithelial hyperplasias and crystalluria could be demonstrated, although all 3 bladder tumours were associated with some form of mineralisation. Results suggest a particular susceptibility of males to saccharin treatment. The possibility that saccharin may promote, or enhance, the development of latent tumour cells already present in the experimental population, rather than initiate carcinogenesis per se is considered.
Effect of quinolones on the duration of salmonella carriage after acute salmonellosis

Field: Medicine (Health Sciences)

Carlstedt et al. (I) studied the effect on the duration of salmonella carriage of norfloxacin treatment of acute salmonellosis during an outbreak of infection with Salmonella typhimurium. They found that norfloxacin treatment did not shorten the carrier stagc. The authors state that ... no controlled study has been published on the effect of quinolones on salmonella convalescent carriage.'. However. in a rcccnt study during an outbreak of food poisoning caused by S. typhimurium, we investigated the duration of fecal excretion of salmonella for patients who received no antibiotic treatment and for those treated with ofloxacin (2). 20 inpatients with positive stool cultures received 200 mg ofloxacin twice daily for 5 days. 21 outpatients with positive stool cultures did not receive any drug. In the untreated group. 18/21 patients (85.7%) were excreting S. typhimurium after 8 days and 6/21 (28.5%) after 18 days. In the ofloxacin-treated group 5/20 patients (25%) were excreting S. typhimurium after 8 days and 1/20 (5%)) after 18 days. The differcnces were statistically significant (Student's I test). Thus. wc found that ofloxacin shortens the duration of excretion of S. typhimurium in feces. In somc recent studies it has been shown that ciprofloxacin also shortens the carrier stage after acute salmoncllosis (3,J). Carlstedt et al. state that .'... it seems unlikely that other quinolones would he more successful. However. there may he differences hctwccn the effect of norfloxacin and other quinolones on the duration of fecal excretion of salmonella in salmonella enterocolitis depending on different pharmacokinetics.
Magnetic and electron transport properties of the rare earth cobaltates, La0.7 xLnxCa0.3CoO3(Ln = Pr, Nd, Gd and Dy): a case of phase separation

Field: Physics and Astronomy (Physical Sciences)

Magnetic and electrical properties of four series of rare earth cobaltates of the formula La0.7-xLnxCa0.3CoO3 with Ln = Pr, Nd, Gd and Dy have been investigated. Compositions close to x = 0.0 contain large ferromagnetic clusters or domains, and show Brillouin-like behaviour of the field-cooled DC magnetization data with fairly high ferromagnetic Tc values, besides low electrical resistivities with near-zero temperature coefficients. The zero-field-cooled data generally show a non-monotonic behaviour with a peak at a temperatures slightly lower than Tc. The near x = 0.0 compositions show a prominent peak corresponding to the Tc in the AC-susceptibility data. The ferromagnetic Tc varies linearly with x or the average radius of the A-site cations, (rA). With increase in x or decrease in (rA), the magnetization value at any given temperature decreases markedly and the AC-susceptibility measurements show a prominent transition arising from small magnetic clusters with some characteristics of a spin-glass. Electrical resistivity increases with increase in x, showed a significant increase around a critical value of x or (rA), at which composition the small clusters also begin to dominate. These properties can be understood in terms of a phase separation scenario wherein large magnetic clusters give way to smaller ones with increase in x, with both types of clusters being present in certain compositions. The changes in magnetic and electrical properties occur parallely since the large ferromagnetic clusters are hole-rich and the small clusters are hole-poor. Variable-range hopping seems to occur at low temperatures in these cobaltates.
Enzootic Activity of Chlamydia in Farms Located in a Hotspot Area for Zoonosis Emergence

Field: Veterinary (Health Sciences)

Abstract

Chlamydias are obligated intracellular Gram-negative bacteria, considered important zoonotic pathogens, broadly present in several bird species and responsible for economic losses in animal production. We analyzed the presence of Chlamydial species with zoonotic risk in farm animals in a highly biodiverse area and with great human circulation, the Argentine, Brazil and Paraguay tri-border area. We surveyed nine farms in an area and nasally swabbed a total of 62 animals. DNA was extracted and specific PCR was performed to identify chlamydial species. We detected Chlamydia spp . in 6.5% (4/62) of the animals tested, positive samples belonged to cattle and none of them showed symptoms of respiratory disease nor had been diagnose with reproductive diseases. Specific nested PCR confirmed two samples belonged to C. pecorum and two to C. psittaci . We report for the first time Chlamydia circulation with zoonotic risk in the region. Surveys in birds and wild mammals could give a better understanding to know what Chlamydial species are circulating in the wild interface. The zoonotic potential should be taking into account as farm workers and the surrounding population could be silent carriers or have respiratory diseases being underdiagnosed, and therefore should be considered in the differential diagnoses.
THE POLITICS OF UTILITARIANISM : SOME NOTES ON THE HISTORY OF WORKING‐CLASS TRAINING IN GERMANY1

Field: Social Sciences (Social Sciences)

Abstract 1Revised and expanded version of a paper originally presented to the International Standing Conference for the History of Education, Leuven/Louvain, September 24–27,1979. Notes 1Revised and expanded version of a paper originally presented to the International Standing Conference for the History of Education, Leuven/Louvain, September 24–27,1979.
Extraction method of scallop areas considering bottom sediment of seabed

Field: Computer Science (Physical Sciences)

Each related organization conducts various fishery investigations and collects data required for estimation of resource state. In the scallop culture industry in Abashiri, Japan, the fisheries are investigated by analyzing seabed images. Seabed images are now obtainable from catamaran technology. However, there is no automatic technology to measure data from these images, and so the current investigation technique is the manual measurement by experts. The scallop lives on seabed of gravel, granule, ballas, coarse sand, and fine sand. The scallop is looked different from each environments. In fine sand fields, the scallop areas have only the shelly rim features in sand field, because the scallop is covered with sand. It is needed to extract the scallop area that the field of seabed image is identified because the method is selected by the fields. In this paper, we propose a method to classify the bottom sediments of the seabed image using the gray level co-occurrence matrix (GLCM). Moreover, we describe a method to extract scallop areas in fine sand field using the result of the bottom sediments, present the results, and evaluate the method's effectiveness.
Inhaled magnesium fluoride reverse bronchospasma

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Asthma is a global health problem. Asthma attacks are becoming more severe and more resistant to usual treatment by beta(2) agonists nebulisation. The search for a new product that could reduce the morbidity of asthmatic disease seems necessary. The objective of this study was to compare the effectiveness of inhaled magnesium fluoride (MgF(2)) with that of magnesium sulphate (MgSO(4)) 15% alone and sodium fluoride (NaF) 0.5 M alone in rats pre-contracted by methacholine (MeCh). Fifty six adult male Wistar rats of medium weight 259 +/- 15 g were divided randomly into five groups. They inhaled respectively: MeCh, MgF(2) + NaCl 0.9%, MgF(2) + acetic acid, MgSO(4) 15% single and NaF (0.5 M) single. Airway resistances were measured after each dose of MeCh by pneumomultitest equipment. Results indicated that (1) MgF(2) + NaCl 0.9%, MgF(2) + acetic acid and MgSO(4) reversed significantly the methacholine-induced bronchial constriction in rats and had a bronchodilating effect at the moment of its administration (2) MgF(2) + acetic acid led to a greater decrease (P<0.05) of bronchial resistances when compared to that obtained from MgF(2) + NaCl 0.9%, NaF exclusively and MgSO(4) alone (3) inhaled NaF alone led to a significant bronchorelaxing effect (P<0.05) that starts at the sixth dose of MeCh (17 mg/L). As a matter of fact, MgF(2) dissolved in acetic acid and delivered in aerosol form reduces significantly bronchial spasm. In conclusion, MgF(2) can be used as a bronchodilator for diseases with bronchospasma such as asthma and chronic obstructive pulmonary disease (COPD).