jimnoneill/paper-to-field-training huggingface dataset:
Use of a Modified Minicoil for Continuous Dialysis

Field: Medicine (Health Sciences)

DiscussionIt has been quite definitely established that progestogen- oestrogen oral contraception is very effective with certain recognized but not serious side-effects.Our more recent efforts, and those of most other investigators of these compounds, have taken two major directions: (1) a search for better and lower- dosage products; (2) a detailed investigation of the possible long-term effects of these compounds on various organs and body functions, and the determination of the safety, or lack of safety, of many years of consistent use by the same individual.Since most women now using these products generally take them for family-planning purposes rather than to avoid any further pregnancies, data on long-term continuous use are not easy to obtain.In our clinic the number of women who have used any of our oral contraceptive preparations for over five years continuously is less than 300, and our studies, with those of Pincus, constitute the longest investigations of this form of contraception.Therefore the total number of con- tinuous users for over five years anywhere is likely to be very limited.It is important that long-term data about continuous use be obtained, because, as this form of contraception is being employed more and more by younger women, we will have millions who may complete their families between the ages of 25 and 30, and they will be depending on the continuous use of these products for another 15 to 20 years.The detailed blood-chemistry studies we have referred to in this report provide one method of obtaining needed information regarding safety.One problem in obtaining this type of information is that certain abnormalities may be found, and they are not necessarily suggestive of pathology.This may hold particularly true, for example, for such changes as eleva- tions in protein-bound iodine.One would be rash, I believe, in deducing a state of hyperthyroidism because the protein- bound iodine in a patient exceeded the usual normal limit of 8 ttg./100 ml.We therefore have to attempt to correlate any
The role of NT-proBNP in patients discharged after COVID-19 pneumonia

Field: Medicine (Health Sciences)

Abstract Funding Acknowledgements Type of funding sources: None. Aims The long-term health effects after SARS-CoV-2 infection remain poorly understood. The aim of our study was to define the cardiac disorders in the early postCOVID period. Methods and resuts Was observed 85 patients (40 (47,1%) men, 45 (52,9%) women, average age – 44,2 (39,3; 47,1)) on 48,3 (45,0; 56,2) days after the onset of the first symptoms of COVID-19. The main group were divided into 3 subgroups: 1 – 39 patients after moderate COVID-19 pneumonia, 2 – 36 patients after severe COVID-19 pneumonia, 3 – 10 patients after critical COVID-19 pneumonia. The subgroups were comparable in gender and age. All patients before COVID-19 were virtually healthy and had no history of cardiovascular disease, including arrhythmias. All patients underwent general clinical methods of examination, determination of SpO2, echocardiography and measured NT-proBNP concentration in serum. In 100% patients was the level of SpO2 more than 95% (average 97,5 (96,3; 98,8)%) and preserved left ventricular ejection fraction (LVEF) (average 62,3 (60,2; 74,3)%). In patients after moderate COVID-19 pneumonia, the level of NT-proBNP was significantly lower (79,4 (59,9; 75,3) pg/ml) than in patients after severe (145,0 (66,9; 170,9) pg/ml) and critical (149,7 (79,3; 138,5) pg/ml) COVID-19 pneumonia (p &lt; 0,01). But concentration NT-proBNP in patients after severe and critical COVID-19 pneumonia didn’t differ significantly (p &gt; 0,05). Conclusions Patients after severe and critical COVID-19 pneumonia are at risk for developing cardiac disorders in the early postCOVID period. Determining the level of NT-proBNP, and not just performing echocardiography, after discharged in such patients will help to customize the most appropriate therapeutic strategies.
Manchester: Skills, Devolution and Accountability?

Field: Social Sciences (Social Sciences)

Skills policy has consistently played a central part in Greater Manchester's (GM) vision for devolution. From New Labour in the late 1990s to the Conservatives following their General Election victory in May 2015, GM's leaders have lobbied Westminster for devolved powers over a wide range of areas. Skills policy and funding has been at the heart of this vision for the city and its wider region. This paper explores the rationale for doing so as well as providing an account of how decisions have been made at both the local and national level. Key players and policy moments are described as this is an account of 'policy actors' and 'policy windows'. From Sir Howard Bernstein and Sir Richard Leese to Tony Blair and George Osborne, this has been a story of preparation and persistence but also of the identification and seizing of key moments and opportunities. The paper also considers the present and the approaching future, the precise powers that are now being established and the new models of democratic accountability that surround them. Ultimately, the paper asks whether either are enough?
Synthesis of N4‐Amino and N4‐Hydroxy Derivatives of 5‐Azacytidine. A Facile Rearrangement of the N4‐Amino Derivative to 5‐(3‐β‐D‐Ribofuranosylureido)‐1H‐1,2,4‐triazole.

Field: Chemistry (Physical Sciences)

Abstract For Abstract see ChemInform Abstract in Full Text.
Conservation of the genetic resources of Vitis

Field: Agricultural and Biological Sciences (Life Sciences)

As an alternative or supplement to field collections, a repository of 35 grapevine genotypes and 15 clones of cv. Optima was set up under minimal growth conditions. To prolong the storage period between subculturing to at least 12-18 months, some factors of long-term storage were optimized and the causes responsible for early senescence of sensitive genotypes were investigated Besides indirect effects due to excision time, origin of the starting material and preculture, there is a direct influence of the light conditions on the survival rate of cultures. CCC application showed, in some cases, positive effects only after long-term storage. An increase of carbon dioxide concentration during storage is considered to be responsible for the early death of some cultures.
Assessment of degradation of semidesert and arıd steppe field landscapes and pasture lands under the condition of modern climate change

Field: Environmental Science (Physical Sciences)

It was determined that degradation of pasture soils in semi-desert and arid field landscapes of the Kur depression intensified under the condition of modern climate changes. Temperature rose 1,2°C, the precipitations amount was 65,7 mm in 1995–2015 in comparison with 1970–1994. These changes are resulted in landscape desertification and soils degradation. Main criteria were adopted for degradation assessment, and plant cover degradation, water erosion, defilation and salinization are concerned here. The features of these processes were defined depending on desertification degrees. The pastures were divided into 3 parts: useful, limited useful, useless. The relief of the useful zone occupies the zones with unchanged morphological signs less than 7° of inclined degree, and not exposed to negative processes, with the precipitations amount more than 300 mm. The limited useful pastures are: morphological signs changed to a mean degree (inclination of soils is 17–15°), exposed to changed negative processes to a weak and mean degree, precipitation number is 300–250 mm. The useless soils are: inclination is more than 15°, morphological features are fully disturbed, strongly exposed to negative processes, the precipitation number is less than 250 mm.
The life cycle of Chloromyxum auratum (Myxozoa) from goldfish, Carassius auratus (L.), involves an antonactinomyxon actinospore

Field: Agricultural and Biological Sciences (Life Sciences)

The myxozoan parasite Chloromyxum auratum Hallett, Atkinson, Holt, Banner Bartholomew, 2006, was shown experimentally to have a two-host life cycle which involved a previously undescribed antonactinomyxon actinospore stage. Myxospores obtained from gall bladders of naturally infected feral goldfish, Carassius auratus (L.), were used to infect samples of mixed species of oligochaete worms obtained from the same locality as the fish: Fern Ridge Dam, Oregon, USA. After some 110 days post-exposure, actinospores were detected from the water above the oligochaetes. The 18S rDNA sequence of these actinospores was identical to the original myxospores. Spore release was sporadic, of low intensity and short duration, which confounded efforts to identify the host oligochaete species and infect naive fish. This is the first life cycle that incorporates an actinospore of the collective group Antonactinomyxon, and the first life cycle demonstrated in the laboratory for a species of Chloromyxum.
Genetics of Field Resistance of Rice to Brown Planthopper1

Field: Agricultural and Biological Sciences (Life Sciences)

The brown planthopper [ Nilaparvata lugens (Stal)] is one of the most serious insect pests of rice ( Oryza sativa L.) in South and Southeast Asia. Because cultivars with vertical resistance to brown planthopper have “broken down” due to brown planthopper biotype selection, field resistant cultivars with horizontal resistance are being evaluated. The inheritance of field resistance to brown planthopper in two traditional rice cultivars, ‘Utri Rajapan’ and ‘Triveni’, was investigated. Twenty‐day old seedlings were infested with second and third‐instar brown planthopper nymphs. Reactions of F 1 , F 2 , and F 3 populations from the crosses of resistant cultivars with the susceptible parent ‘TN1’ revealed that two independently segregating recessive genes govern resistance in both cultivars. Allelism tests revealed that the two cultivars have the same genes for resistance.
C1-Esterase Inhibitor in Uncomplicated Pregnancy and Mild and Moderate Preeclampsia

Field: Medicine (Health Sciences)

Summary Routine coagulation tests and measurement of the plasma levels of C1-esterase inhibitor (C1-INH) and antithrombin III were performed in 17 women with mild preeclampsia, 10 women with moderate preeclampsia and 20 women with uncomplicated pregnancy. All pregnant probands were within the third trimester of pregnancy. 20 non-pregnant women were used as controls. The gfoups were matched in age and the pregnant ones were also matched in gestational age. C1-INH activity and antigen were significantly reduced (p <0.002) in normally pregnant women as compared with nonpregnant ones. Further, CI-INH activity was lower in women with mild preeclampsia and significantly lower in women with moderate preeclampsia (p <0.05) as compared with normally pregnant women. None of the plasmatic coagulation tests was indicative of a consumption reaction. We conclude that C1-INH activity and antigen reductions are commonly associated with pregnancy. Furthermore, as markedly lower values can be found in mild and moderate preeclampsia, measurement of the C1-INH activity in pregnant women within the third trimester might proof useful to establish the diagnosis of a preeclamptic condition.
Improved Positioning Precision using a Multi-rate Multi-sensor in Industrial Motion Control Systems

Field: Engineering (Physical Sciences)

Industrial motion control systems, e.g. pick-andplace tasks in semiconductor manufacturing equipment, require precise positioning for achieving high machine throughput. Linear encoders are the standard industrial sensors used for position feedback due to their relatively low cost, high resolution, and high operating frequency. The challenge is that the linear encoders measure the positions at the points-ofcontrol of the equipment, e.g. motors, and not at the points-ofinterest, e.g. pick-and-place positions. The coupling between a point-of-control and the point-of-interest is affected by external disturbances such as mechanical misalignment of the product, friction, and warping of the material, and linear encoders fail to sense these disturbances. Vision-based sensing is a potential alternative to achieve robust sensing and high-precision control. However, vision processing has a long computational delay and affects the machine throughput. In this paper, we propose a multi-rate multi-sensor fusion approach to improve the positioning accuracy of industrial motion control systems with different points-of-control and points-of-interest. We present a multi-rate Kalman filter with bias correction to fuse accurate but slow and delayed vision sensor data with fast but less accurate linear encoder data for highprecision position control. We validate the proposed method in an evaluation framework by considering an industrial case study of a semiconductor die-bonding machine. A design-space exploration is done to evaluate the performance of the proposed solution with respect to various relevant design parameters. The effectiveness of the proposed solution depends on the type of disturbances and vision processing delay. For the parameter range under consideration, we achieve a positioning accuracy of 1μm.
Prescription Drug User Fee Statute Enacted

Field: Medicine (Health Sciences)

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On the Reactivity Toward Ketones of New Methyl Amino Complexes of Rh(III) and Ag(I). Synthesis of Ortho-Rhodiated Acetophenone Methyl Imine Complexes

Field: Chemistry (Physical Sciences)

MeNH(2) reacts with silver salts AgX (2:1) to give [Ag(NH(2)Me)(2)]X [X = TfO = CF(3)SO(3) (1.TfO) and ClO(4) (1.ClO(4))]. Neutral mono(amino) Rh(III) complexes [Rh(Cp*)Cl(2)(NH(2)R)] [R = Me (2a), To = C(6)H(4)Me-4 (2b)] have been prepared by reacting [Rh(Cp*)Cl(mu-Cl)](2) with RNH(2) (1:2). The following cationic methyl amino complexes have also been prepared: [Rh(Cp*)Cl(NH(2)Me)(PPh(3))]TfO (3.TfO), from [Rh(Cp*)Cl(2)(PPh(3))] and 1.TfO (1:1); [Rh(Cp*)Cl(NH(2)R)2]X, where R = Me, X = Cl, (4a.Cl), from [Rh(Cp*)Cl(mu-Cl)]2 and MeNH2 (1:4), or R = Me, X = ClO4 (4a.ClO4), from 4a.Cl and NaClO4 (1:4.8), or R = To, X = TfO (4b.TfO), from [Rh(Cp*)Cl(mu-Cl)](2), ToNH(2) and TlTfO (1:4:2); [Rh(Cp*)(NH(2)Me)(tBubpy)](TfO)(2) (tBubpy = 4,4'-di-tert-butyl-2,2'-bipyridine, 5.TfO), from 2a, TlTfO and tBubpy (1:2:1); [Rh(Cp*)(NH(2)Me)(3)](TfO)2 (6.TfO) from [Rh(Cp*)Cl(mu-Cl)](2) and 1.TfO (1:4). 2-6 constitute the first family of methyl amino complexes of rhodium. 1 and 4a.ClO(4) react with acetone to give, respectively, the methyl imino complexes [Ag{N(Me)=CMe(2)}()]X [X = TfO (7.TfO), ClO(4) (7.ClO(4))], and [Rh(Cp*)Cl(Me-imam)]ClO(4) [8.ClO(4), Me-imam = N,N'-N(Me)=C(Me)CH(2)C(Me)(2)NHMe]. 7.X (X = TfO, ClO(4)) are new members of the small family of methyl acetimino complexes of any metal whereas 8.ClO4 results after a double acetone condensation to give the corresponding bis(methyl acetimino) complex and an aldol-like condensation of the two imino ligands. The acetimino complex [Ag(NH=CMe(2))(2)]ClO(4) reacts with [Rh(Cp*)Cl(imam)]ClO(4) [1:1, imam = N,N'-NH=C(Me)CH(2)C(Me)(2)NH(2)] to give [Rh(Cp*)(imam)(NH=CMe(2))](ClO(4))(2) (9a.ClO(4)). 8.ClO(4) reacts with AgClO(4) (1:1) in MeCN to give [Rh(Cp*)(Me-imam)(NCMe)](ClO(4))2 (9b.ClO(4)), which in turn reacts with XyNC (Xy = C(6)H(3)Me(2)-2,6) or with MeNH(2) (1:1) to give [Rh(Cp*)(Me-imam)L](ClO(4))(2) [L = XyNC (9c.ClO(4)), MeNH(2) (9d.ClO(4))]. 6.TfO reacts with acetophenone to give [Rh(Cp*){C,N-C(6)H(4)C(Me)=N(Me)-2}(NH(2)Me)]TfO (10a.TfO), the first complex resulting from such a condensation and cyclometalation reaction. In turn, 10a.TfO reacts with isocyanides RNC (1:1) at room temperature to give [Rh(Cp*){C,N-C(6)H(4)C(Me)=NMe-2}(CNR)]TfO [R = tBu (10b.TfO), Xy (10c.TfO)], or 1:12 at 60 degrees C to give [Rh(Cp*){C,N-C(=NXy)C(6)H(4)C(Me)=N(Me)-2}(CNXy)]TfO (11.TfO). The crystal structures of 9a.ClO(4).acetone-d6, 9c.ClO(4), and 10a.TfO have been determined.
Challenges in Modeling Drug Shortage Events in the Pharmaceutical Domain

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Meeting demand for medicines translates into a very difficult manufacturing, supply chain and commercial optimization problem for every pharmaceutical company. Time series data reflecting missing stock, disease incidence, sales, marketing and others can help with better demand forecasting and supply planning. Accurate demand forecast ensures an optimal functioning of the healthcare environment, however modeling multivariate data in this domain remains challenging. In this article, we describe the typical data types and the modeling problems faced by the pharmaceutical domain regarding missing stock forecasting. We want to motivate the research community to turn their attention onto a set of problems that are highly complex, under explored, but at the same time critically relevant for a highly important domain.
Functional analysis of endo‐1,4‐β‐glucanases in response to Botrytis cinerea and Pseudomonas syringae reveals their involvement in plant–pathogen interactions

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract Plant cell wall modification is a critical component in stress responses. Endo‐1,4‐β‐glucanases ( EG s) take part in cell wall editing processes, e.g . elongation, ripening and abscission. Here we studied the infection response of S olanum lycopersicum and A rabidopsis thaliana with impaired EG s. Transgenic TomCel1 and TomCel2 tomato antisense plants challenged with P seudomonas syringae showed higher susceptibility, callose priming and increased jasmonic acid pathway marker gene expression. These two EG s could be resistance factors and may act as negative regulators of callose deposition, probably by interfering with the defence‐signalling network. A study of a set of Arabidopsis EG T‐ DNA insertion mutants challenged with P . syringae and B otrytis cinerea revealed that the lack of other EG s interferes with infection phenotype, callose deposition, expression of signalling pathway marker genes and hormonal balance. We conclude that a lack of EG s could alter plant response to pathogens by modifying the properties of the cell wall and/or interfering with signalling pathways, contributing to generate the appropriate signalling outcomes. Analysis of microarray data demonstrates that EG s are differentially expressed upon many different plant–pathogen challenges, hormone treatments and many abiotic stresses. We found some A rabidopsis EG mutants with increased tolerance to osmotic and salt stress. Our results show that impairing EG s can alter plant–pathogen interactions and may contribute to appropriate signalling outcomes in many different biotic and abiotic plant stress responses.
Workplace Spirituality and Employee Attitudes within the Lodging Environment

Field: Business, Management and Accounting (Social Sciences)

This research examined the workplace spirituality concept and its relationship with employee variables, including intrinsic work satisfaction, job involvement, intention to quit, organizational based self-esteem, and organizational commitment, within the lodging setting. Workplace spirituality is a growing trend not only in the research community, but also in the corporate environment. Researchers sampled employees from two hotel management groups, one that actively promoted workplace spirituality within its organization and one that did not. The results of this study found a significant relationship between the presence of workplace spirituality and the employee variables being examined. There was also a significant difference examined between the two organizations as related to the presence of workplace spirituality.
Reduced Prospective Motor Control in 10-Month-Olds at Risk for Autism Spectrum Disorder

Field: Neuroscience (Life Sciences)

Motor impairments are not a part of the diagnostic criteria for autism spectrum disorder (ASD) but are overrepresented in the ASD population. Deficits in prospective motor control have been demonstrated in adults and older children with ASD but have never before been examined in infants at familial risk for the disorder. We assessed the ability to prospectively control reach-to-grasp actions in 10-month-old siblings of children with ASD (high-risk group, n = 29, 13 female) as well as in a low-risk control group ( n = 16, 8 female). The task was to catch a ball rolling on a curvilinear path off an inclined surface. The low-risk group performed predictive reaches when catching the ball, whereas the high-risk group started their movements reactively. The high-risk group started their reaches significantly later than the low-risk group ( p = .03). These results indicate impaired prospective motor control in infants susceptible for ASD.
Product Platform Development: Considering Product Maturity and Morphology

Field: Business, Management and Accounting (Social Sciences)

In this paper we continue our development of a structured methodology for product platform development suited to the early design stages. In addition to the previous focus on differences between new and mature products, we now consider how platform development is influenced by the morphology of a product. Purely physical products (e.g., a vacuum cleaner) often pose fewer challenges when undergoing platform design. However, products such as software, service offerings, or process-oriented solutions require adapting previous platform methods in order to accommodate the “amorphous” nature of the system. This paper includes a review of the recent literature in this area, and presents the authors latest platform methodology from the perspective of product morphology and maturity. Illustrative examples are used throughout.
Glostik Willy Live at Mac's Mitten Jam 2012 on 2012-10-06

Field: Arts and Humanities (Social Sciences)

1. Plane Crash (moe Cover) 2. Gonzo Tree 3. Walkin' Apples 4. Highs & Lows 5. Golem in the Shed 6. Peppermint 7. 427 http://glostikwilly.webs.com http://rageview.webs.com http://fmmusiclive.com Sound Mix: Adam Kistler
Dung Beetles Attracted to Feces of Japanese Black Bear (Ursus thibetanus japonicus).

Field: Agricultural and Biological Sciences (Life Sciences)

ツキノワグマの糞に飛来する食糞性コガネムシ (以下糞虫) を山梨県芦川村および東京都奥多摩町で調査した。18種が確認された。いずれも広域に分布し, 他の動物の糞でも確認されている種であった。種により季節消長は異なり, 5種は春から秋にかけて成虫が出現したが, 13種は特定の季節のみ成虫の出現が確認された。日周消長は, トラップで採集された10種のうち5種は昼間中心に, 4種は夜間中心に飛来する種, 1種は季節的に活動時間帯が変化する種であった。糞虫の活動場所は, 8種はdwellerで, 糞の表面および糞の内部でのみ確認された。10種はtunnellerで, 糞下部の土壌内からも糞とともに確認された。Tunnellerは, 産卵期以外も, 糞とともに土壌内から確認された。ツキノワグマの糞に数多く飛来した, コブマルエンマコガネ, クロマルエンマコガネ, マエカドコエンマコガネはいずれも, 昼間中心に飛来し, tunnellerタイプの糞虫であった。