jimnoneill/paper-to-field-training huggingface dataset:
Hippias Major 301b2-c2: Plato's Critique of a Corporeal Conception of Forms and of the Form-Participant Relation

Field: Arts and Humanities (Social Sciences)

In the final movement of the investigation in Hippias Major, Socrates and Hippias agree that unlike pleasures experienced through taste, touch, and smell, pleasure experienced through sight (Ps), pleasure through hearing (Ph), and pleasure through both sight and hearing (Psh) are beautiful (καλόν). 1 In other words, Ps, Ph, and Psh have something in common, call it K, that makes them beautiful. 2I will speak of Κ as a continuous property, where by a continuous property I mean that if two entities (be they particulars or properties) separately possess a property, then the two entities conjointly possess that property, and vice versa.Accordingly, Ps and Ph each possess K; and Psh, which is a conjunction of Ps and Ph, possesses K. Socrates notes: 'If these pleasures [Ps and Ph] are conjointly affected by something, but 1 Throughout I maintain the traditional translation of 'καλόν'.I agree with Woodruff (1981) that 'fine' has a broader semantic range and in this respect is a more adequate translation; but 'fine' also seems to me rather anemic.In fact, no single English word is satisfactory.2 Of course K is beauty, that is, the beautiful itself (αυτό το καλόν).But it will be convenient to be able to refer to beauty by both means.APEIRON a journal for ancient philosophy and science
Utilização de análise de perigos e pontos críticos para garantia da segurança de alimentos: estudo de caso em uma indústria de pescado

Field: Agricultural and Biological Sciences (Life Sciences)

The system of Hazard Analysis and Critical Control Points (HACCP) seeks the prevention, rationality and specificity to control the risks that a food can offer. The objective of this study was to suggest a HACCP plan for processing line frozen fish fillet in a fish processing company. Were carried out preliminary procedures at plan preparation and implementation of the principles of HACCP. After it was formed the HACCP team was made to the product description, drawn up the flowchart of production and carried out the hazard analysis by the establishment of preventive action. Were identified four Critical Control Points (CCPs) in the flowchart of the process, for which they were established critical limits, corrective actions and monitoring, records and verification procedures. The main preventive action was established to control the temperature for the CCP with a high probability of growth of micro-organisms. The HACCP plan proposed is feasible, however it is necessary to consolidate the implementation of Good Manufacturing Practices (GMP) in the industry and the continuous training of handlers.
The antiviral activity of lichen metabolites against dengue virus

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Dengue fever is one of the mosquito-borne infectious diseases globally. Currently, no specific treatment was established. Depsidones and depsides are one of the most common lichen secondary metabolites produced for the organism’s survival in extreme environments. These compounds have been reported as antivirals against the other virus in Flaviviridae family, hepatitis C virus. In this study, depsidones and depsides were explored for anti-dengue efficacy and cellular toxicity. One depsidone, VK-0014, and two depsides, TT-031 and TT-032, exhibited an anti-DENV2 with effective concentration (EC50) of 17.42 ± 3.21, 2.43 ± 0.19, and 0.91 ± 0.15 µM, respectively. Cytotoxicity concentration (CC50) in Vero cells were 155.83 ± 7.77, 50.13 ± 7.45 and 12.10 ± 0.38 µM, respectively. The most effective compound, TT-031, was further study against DENV1-4 and ZIKV and found similar efficacies. The molecular mechanism studies revealed that the possible targets were cellular components rather than viral protein but the molecular target remains unclear. This study reports lichen depsidones and depsides an anti-DENV and ZIKV leads for the first time and could serve as effective candidates for further development as anti-DENV drugs.
[An urease enzyme linked immunosorbent assay for detection of Helicobacter pylori infection].

Field: Medicine (Health Sciences)

A sensitive and specific serological diagnostic test for Helicobacter pylori infection has been developed and validated in 120 patients with dyspeptic symptoms undergoing endoscopy. This test is to use urease, a protein unique to H. pylori, as the basis for the enzyme linked immunosorbent assay (ELISA) that detects serum H. pylori urease antibodies. The ELISA mean optical density (OD) in H. pylori-positive group is higher than that in H. pylori-negative group (0.57 +/- 0.23 vs 0.24 +/- 0.15, P < 0.001), a cut-off 0.3 OD yields a sensitivity of 95% and a specificity of 93%. Serum absorption test showed that Escherichia coli, Klebsiella pneumonia, Proteus mirabilis, Yersinia enterocolotica, Pseudomonas aeruginosa cell lysate do not influence serum H. pylori urease antibody level, though they all have urease except E. coli. The result implied that H. pylori urease can be a good antigen to detect serum H. pylori antibody and it would be useful for epidemiological survey and routine diagnostic approach. Nearly half of the blood donors showed positive result with H. pylori urease antibody. It is suggested that H. pylori infection is quite common in the asymptomatic population.
Euclidean position estimation of static features using a moving camera with known velocities

Field: Computer Science (Physical Sciences)

The estimation of 3D Euclidean coordinates of features from 2D images continues to be a problem of significant interest. In this paper we develop a 3D Euclidean position estimation strategy for a static object using a single moving camera whose motion is known. The Euclidean depth estimator which is developed has a very simple mathematical structure and is easy to implement. Numerical simulations are presented to illustrate the performance of the algorithm and an extension for a paracatadioptric system is briefly discussed.
Towards subjectifying text clustering

Field: Computer Science (Physical Sciences)

Although it is common practice to produce only a single clustering of a dataset, in many cases text documents can be clustered along different dimensions. Unfortunately, not only do traditional text clustering algorithms fail to produce multiple clusterings of a dataset, the only clustering they produce may not be the one that the user desires. In this paper, we propose a simple active clustering algorithm that is capable of producing multiple clusterings of the same data according to user interest. In comparison to previous work on feedback-oriented clustering, the amount of user feedback required by our algorithm is minimal. In fact, the feedback turns out to be as simple as a cursory look at a list of words. Experimental results are very promising: our system is able to generate clusterings along the user-specified dimensions with reasonable accuracies on several challenging text classification tasks, thus providing suggestive evidence that our approach is viable.
TREE OF LIFE: TEACHERS’ REFLECTION ON THEIR TEACHING CAREER

Field: Arts and Humanities (Social Sciences)

This article discusses the use of narrative inquiry in educational research and emphasizes the importance of giving teachers opportunities to self-reflect and share their insights with other colleagues. It presents the narratives collected after the first stage, data collection, of an on-going narrative project using the tool ‘Tree of life’ to facilitate teachers’ self-reflection on their teaching career as a professional development activity. This activity provides a large amount of teacher-generated data while allowing teachers to reflect on some critical incidents in their career and gain self-knowledge which is as crucial to good teaching as knowing students and the subject they teach. By telling their stories, teachers can come to know themselves better and really appreciate how much they have accomplished and grown during their career, thereby making appropriate and meaningful plan for future professional development.
Influence of Nonalcoholic Fatty Liver Disease on Locally Advanced Breast Cancer: A Retrospective Cohort Study

Field: Medicine (Health Sciences)

ABSTRACT Background: Nonalcoholic fatty liver disease (NAFLD) is associated with poor prognosis after radical breast cancer surgery. Locally advanced breast cancer (LABC) has a higher recurrence rate than early breast cancer does and requires multidisciplinary treatment including cardiotoxic and liver-metabolized anthracycline. The aim of the current study was to investigate the association between NAFLD and the prognosis and morbidity of patients with LABC. Patients and Methods: This single-center, retrospective, cohort study included patients with stage III breast cancer who underwent surgery between July 2015 and December 2018. Hepatic steatosis was defined as a ratio of liver-to-spleen attenuation (L/S) of <1.12 on pre-treatment unenhanced computed tomography. The primary outcome was recurrence-free survival (RFS). We used the log-rank test to compare survival curves and the Cox proportional hazards model to adjust for covariates. Results: We analyzed 44 patients, including 6 with NAFLD. The median follow-up time was 852.5 days. On univariate and multivariate analyses, NAFLD was not significantly associated with RFS (hazard ratio [HR], 1.474; 95% confidence interval [CI], 0.324–6.706, and HR, 1.297; 95% CI, 0.263–6.399, respectively). Neither cardiovascular events nor secondary cancers were associated with NAFLD. Known prognostic factors of breast cancer—such as older age, high histological grade, and estrogen receptor negativity—were significantly associated with a shorter RFS. Conclusion: When treating patients with LABC, physicians and patients should not worry much about the prognostic impact of mild NAFLD. Highlights:
The Sybil prophecy: Searching for predictors of response to bevacizumab in glioblastoma

Field: Medicine (Health Sciences)

Journal Article Corrected proof The Sybil prophecy: Searching for predictors of response to bevacizumab in glioblastoma Get access Martina Offi, Martina Offi Department of Neuroscience, Catholic University School of Medicine, ItalyDepartment of Neurosurgery, Fondazione Policlinico Gemelli IRCCS, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar Lucia Gabriele, Lucia Gabriele Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar Giulia Romagnoli, Giulia Romagnoli Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar Liverana Lauretti, Liverana Lauretti Department of Neuroscience, Catholic University School of Medicine, ItalyDepartment of Neurosurgery, Fondazione Policlinico Gemelli IRCCS, Italy https://orcid.org/0000-0001-7997-1624 Search for other works by this author on: Oxford Academic PubMed Google Scholar Roberto Pallini, Roberto Pallini Department of Neuroscience, Catholic University School of Medicine, ItalyDepartment of Neurosurgery, Fondazione Policlinico Gemelli IRCCS, Italy Corresponding Author: Roberto Pallini, MD, PhD, Department of Neuroscience, Catholic University School of Medicine, and Department of Neurosurgery, Fondazione Policlinico Gemelli IRCCS, Largo A. Gemelli, 8, 00168 Rome, Italy (roberto.pallini@unicatt.it). https://orcid.org/0000-0002-4611-8827 Search for other works by this author on: Oxford Academic PubMed Google Scholar Quintino Giorgio D'Alessandris Quintino Giorgio D'Alessandris Department of Neuroscience, Catholic University School of Medicine, ItalyDepartment of Neurosurgery, Fondazione Policlinico Gemelli IRCCS, Italy Search for other works by this author on: Oxford Academic PubMed Google Scholar Neuro-Oncology, noae088, https://doi.org/10.1093/neuonc/noae088 Published: 17 June 2024 Article history Corrected and typeset: 17 June 2024 Published: 17 June 2024
NONARTERITIC ANTERIOR ISCHEMIC OPTIC NEUROPATHY ASSOCIATED WITH PARACENTRAL ACUTE MIDDLE MACULOPATHY AND CILIORETINAL ARTERY OCCLUSION: MULTIMODAL IMAGING OF A NEWLY DESCRIBED CLINICAL ASSOCIATION

Field: Medicine (Health Sciences)

Purpose: The purpose of this study was to report multimodal imaging features of a novel association of nonarteritic anterior ischemic optic neuropathy, paracentral acute middle maculopathy, and cilioretinal artery occlusion. Methods: A 74-year-old male patient presented complaining of an acute subjective decline in visual acuity in the right eye over the previous days. This patient underwent a comprehensive ophthalmologic assessment, including multimodal retinal imaging and visual field test. Results: The eye examination revealed yellowish optic disk edema in the right eye with peripapillary hemorrhages and a whitish lesion extending from the temporal margin of the optic nerve head toward the macula. Multimodal imaging confirmed the diagnosis of nonarteritic anterior ischemic optic neuropathy in the right eye. Notably, the structural B-scan and en face optical coherence tomography images revealed hyperreflective areas in the inner and mid retinal layers, indicating an association with cilioretinal artery occlusion and paracentral acute middle maculopathy. Conclusion: The authors herein describe the clinical findings of a previously unreported association among nonarteritic anterior ischemic optic neuropathy, cilioretinal artery occlusion, and paracentral acute middle maculopathy.
SUPERCONDUCTIVE ACTIVITIES AT COSY FZJ

Field: Physics and Astronomy (Physical Sciences)

A shielded test facility has been constructed to allow RF tests of superconductive (sc) cavities. Measurements of sc cavities are possible up to 500W in a frequency range from 80MHz to 1GHz. Additionally a 25kW TV transmitter has been installed together with a high power circulator. The first sc experience has been made at a 5-cell 500 MHz, β=0.75 test cavity for the ESS. First quasi-static measurements using the 500W broadband amplifier almost verified the design values of Q0=2×109 and Eacc&gt;5MV/m. The tuning system of the cavity consists of a coarse system driven by a stepper motor and a piezoelectric fine tuner. The piezoelectric tuning system has been used to record the spectrum of mechanical resonances of the cavity. Furthermore, dynamical data of the Lorentz force detuning have been taken during pulsed-mode operation at a repetition rate of 50Hz. First results of active compensation of the Lorentz force detuning, using the fast piezo frequency control system, are presented. A digital diagnostic tool has been added to measure the phase in the order of 0.1 ° which will be required for a fast digital control system. A vertical cryostat down to 2K will be installed in the test area to perform studies for the planned multicell spoketyp, elliptical cavities and QWRs. The QWRs are proposed for the LINAC project, which will feed the Cooler Synchrotron COSY with protons and deuterons up to
Spatial and temporal changes in dry spells in a Mediterranean area: Tuscany (central Italy), 1955–2017

Field: Environmental Science (Physical Sciences)

Abstract Global change affects precipitation and small modifications in rainfall regimes could compromise water availability, especially in areas characterized by a strong seasonality and a climate ranging from dry sub‐humid to semi‐arid. Drought, in particular, is a creeping phenomenon defined as an important temporary decrease in water availability below the expected value in a certain period and a specific area. Among the different methodologies for analysing drought periods, one of the most used is the evaluation of dry spells. The aim of this study is to investigate spatial and temporal changes in dry spells in Tuscany during the period 1955–2017, by using daily precipitation data. Changes in the number of dry days, maximum duration and 75th percentile of the duration of the dry spells were investigated. Three precipitation thresholds were selected: 1, 5 and 10 mm. The analyses were carried out at annual, September–May, September–November and December–May level. Theil–Sen nonparametric method was used to estimate the slope; Mann–Kendall test and a modification of it, which applies a trend‐free pre‐whitening (TFPW) method to the series having a serial correlation, were applied to look for statistically significant trends. The drought indicators showed increasing trends (some significant) especially at December–May and to a lesser extent at the annual and September–May level; the most pronounced increases were found in the southernmost areas of Tuscany. During September–November period, on the other hand, a prevalence of decreasing trends (rarely significant), with less pronounced decreases in the south of the region, were observed. Mediterranean area is considered a climate change “hot‐spot” from the viewpoint of vulnerability. An increase in long‐lasting dry spells, especially in southern Tuscany, can exacerbate the problems linked to water management and demand.
Specific absorption rate and temperature increases in the head of a cellular-phone user

Field: Medicine (Health Sciences)

In this paper, a complete electromagnetic and thermal analysis has been performed considering the head of a subject exposed to various kinds of cellular phones available on the market, and focusing the attention on important organs like the eye lens and brain. Attention has first been posed on a particular phone model, and a comparison between the absorbed power distribution and steady-state temperature increases has been carried out. The influence of different antennas (dipole, monopole, whip, and planar inverted F antenna) on the power absorption and on the consequent tissue heating has then been analyzed. The obtained results show, for a radiated power of 600 mW, maximum SAR values, averaged over 1 g, from 2.2 to 3.7 W/kg depending on the considered phone. The maximum temperature increases are obtained in the ear and vary from 0.22 C to 0.43 C, while the maximum temperature increases in the brain lie from 0.08 C to 0.19 C. These steady-state temperature increases are obtained after about 50 min of exposure, with a time constant of approximately 6 min. Finally, the results evidence a maximum temperature increase in the external part of the brain from 0.10 C to 0.16 C for every 1 W/kg of SAR, averaged over 1 g of brain tissue.
Impact of Design on Force between Flexor Tendons and Distal Radius Volar Plates

Field: Medicine (Health Sciences)

Background Flexor tendon injury is a rare but serious complication of distal radius volar plating. Purpose This study aims to determine whether the design of distal radius volar plates impacts the amount of force exerted on the flexor digitorum profundus (FDP) and flexor pollicis longus (FPL) tendons when the plates are placed proximal and distal to the watershed line. Methods Three commercially available plates were applied to 10 fresh, matched-pair upper extremity specimens. Cyclical loading was applied to the tendons, and the force generated between tendon and plate was measured. Linear mixed effect models were used to evaluate differences in maximum and mean forces by plate position, plate design, and the interaction between position and design. Results Forces on the tendons differed significantly by position but not plate design. For the FPL tendon, the average maximum force with a plate in Soong's grade 2 was 4.50 (95% confidence interval [CI]: 2.8–7.3) times higher than when the plate was in a Soong's grade 0 placement, and 4.63 (95% CI: 2.82–7.61) times higher for the FDP tendon. While not statistically significant, lower observed force values with thinner plates when plates were placed distal to the watershed line suggest that that plate thickness could also be a critical plate characteristic for distally placed plates. Conclusion Despite differences in plate design, the main determinant of plate prominence and therefore flexor tendon injury potential is placement in relation to the watershed line. Clinical Relevance This study may help to guide surgeon implant selection and volar plate design.
Case Report: Case Series of Human Plasmodium knowlesi Infection on the Southern Border of Thailand

Field: Medicine (Health Sciences)

Although human infections of Plasmodium knowlesi have been found throughout Southeast Asia, most cases originated from Malaysian Borneo. In Thailand, P. knowlesi malaria was considered extremely rare. However, during October 2017–September 2018, there was a surge in the number of reported P. knowlesi cases. Here, a series of six cases of P. knowlesi malaria found during this period in Songkhla and Narathiwat provinces of southern Thailand are presented. All cases were confirmed by polymerase chain reaction. The unprecedented case number in the affected area is a warning sign of an increasing P. knowlesi burden in the south of Thailand.
A methodology for optimizing the selection of decoupling components for power delivery systems of high-performance ASICs

Field: Engineering (Physical Sciences)

This paper describes an approach for optimizing the selection of de-coupling components for the power delivery network of a high-performance ASIC package. The proposed approach is aimed at reducing the guess-work that is typically associated with the design of an appropriate de-coupling scheme, which meets desired performance targets. It is partly based on constructing a distributed circuit model of the entire power delivery system (package and board) with sufficient spatial (and frequency) resolution, supplemented by exploiting the simple concepts of resonant circuit characteristics over a desired frequency band. The application of the methodology is illustrated for a high-end ASIC package, which has limited package-level and board-level resources.
Essential Oil Constituents of “PAEONIAE RADIX”Peaonia lactifloraPall. (P. albiloraPall.)

Field: Chemistry (Physical Sciences)

Journal Article Essential Oil Constituents of “PAEONIAE RADIX” Peaonia lactiflora Pall. (P. albilora Pall.) Get access Mitsuo Miyazawa, Mitsuo Miyazawa Departments of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Kowakae, Higashiosaka-shi, Osaka 577, Japan Search for other works by this author on: Oxford Academic Google Scholar Haruo Maruyama, Haruo Maruyama Departments of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Kowakae, Higashiosaka-shi, Osaka 577, Japan Search for other works by this author on: Oxford Academic Google Scholar Hiromu Kameoka Hiromu Kameoka Departments of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Kowakae, Higashiosaka-shi, Osaka 577, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 48, Issue 11, 1 November 1984, Pages 2847–2849, https://doi.org/10.1080/00021369.1984.10866600 Published: 01 November 1984 Article history Received: 29 March 1984 Published: 01 November 1984
T Lymphocyte Subgroups and Erythrocyte Immune Function in Parkinson Disease Patients

Field: Medicine (Health Sciences)

Objective To study the T lymphocyte subgroups and the erythrocyte immune function of Parkinson disease(PD).Methods T lymphocyte subgroups and erythrocyte immune function of 20 cases of PD were measured. Ten of 20 cases were compared before and after administration of levodopa.Results The levels of CD3, CD4, and CD8 in PD were depressed; the levels of RBC-ICR in PD were increased,as compared with healthy controls. After administration of levodopa, the CD3,CD8 were increased; while the RBC-ICR was decreased.Conclusions The present study demonstrates that T lymphocytes is at low immune functional state while circulating immune complex is increased. The abnormal immune function in PD can be improved by application of levodopa, suggesting immune function is out of way in PD related to dopamine levels in the central nervous system.