jimnoneill/paper-to-field-training huggingface dataset:
THE PROGNOSTIC IMPORTANCE OF â€œCD 133 MARKERâ€ IN THE CARCINOGENESIS OF COLORECTAL ADENOMATOUS POLYPS

Field: Medicine (Health Sciences)

Ponte Academic JournalAug 2020, Volume 76, Issue 8 THE PROGNOSTIC IMPORTANCE OF CD133 MARKER IN THE CARCINOGENESIS OF COLORECTAL ADENOMATOUS POLYPSAuthor(s): Aynur Safiyeva ,Nuru Bayramov, Mustafa Cihat AvundukJ. Ponte - Aug 2020 - Volume 76 - Issue 8 doi: 10.21506/j.ponte.2020.8.6 Abstract:BACKGROUND: The chosen study mainly investigates the adenomatous polyps, which play an essential role in the development of colorectal cancer. The risk of colorectal carcinogenesis can be reduced by polypectomy and close medical surveillance over patients. The importance of stem cells in the development of carcinoma is considered vital. Thus, studying the frequency and prevalence of stem cells in colorectal polyps helps more in the early detection and prevention of cancer in patients. The evaluation of stem cells in adenomatous polyps can provide clear-cut information about the development of carcinoma. METHOD: For this purpose, the study mainly aims to examine the usefulness of CD133, a stem cell marker for the accurate diagnosis of colon polyps. Previously, the colorectal polyps in 60 males and 40 females were pathologically reassessed first at Azerbaijan Medical University and then at the Pathology Department under Meram Medical Faculty. RESULTS: During the investigation, Hematoxylin - Eosin stained preparations were examined and cases with and without dysplasia were identified. CD133 stain was performed immunohistochemically to paraffin blocks of all cases and CD133 stained preparations were investigated by image analysis software and CD133 stained cells in the unit area were automatically integrated into the same image analysis system. At the end of the study, the current clinical information of the cases was reached out, the cases developed malignancy were identified. CONCLUSIONS: In conclusion, amid the investigation, the statistical significance of CD133 expression was detected in cases with the dysplasia and malignancy. 3 Keywords: adenomatous polyps, CD 133, colorectal polyps, dysplasia, malignancy. Download full text:Check if you have access through your login credentials or your institution Username Password
AMINO ACID CHANGES IN THE KOREAN TRADITIONAL FERMENTATION PROCESS FOR BLUE MUSSEL, MYTILUS EDULIS

Field: Agricultural and Biological Sciences (Life Sciences)

The effect of fermentation period on biochemical composition of fermented blue mussel was investigated in three fermentation stages. Fermented blue mussel sauces (FBMSs) were prepared with 25% NaCl (w/w) at 20C for different fermentation periods. The FBMSs were desalted below 1% (w/w) by an electrodialyzer. It was observed that content of protein increased and carbohydrate decreased throughout the fermentation. In addition, the changes of free amino acids were investigated, and the levels of amino acids such as glycine, alanine, proline, aspartic acid and glutamic acid were higher, which may be important for the taste of fish and shellfish sauce.
Improved thermal stability of Mg/Co multilayer by introducing Zr barrier layer

Field: Materials Science (Physical Sciences)

High reflective multilayer mirrors are widely used as optical elements for applications such as extreme ultraviolet (EUV) microscopy, high harmonic femtosecond chemistry, solar astrophysics imaging, and synchrotron radiation. Mg-based multilayers, such as Mg/SiC, Mg/Y2O3 and Mg/Co are promising in the wavelength of 25-40 nm for Mg L3 absorption edge is located at 25 nm. Mg/Co has narrower bandwidth and better thermal stability. In applications such as synchrotron radiation and solar imaging, multilayers mirrors must endure high heat loads. Thus, we investigated the thermal stability of Mg/Co multilayer and then introduced barrier layer to improve thermal stability in this paper. The interface structures evolution was studied by using X-ray reflection/scatter technique. Mg/Co multilayer can be stable when not heated above 300°C. B4C and Zr layers were inserted into Mg/Co multilayer as interface barrier layer to improve thermal stability. According to the measured results, B4C barrier layer is not suitable for Mg/Co multilayer, mainly due to the diffusion between Mg and B4C. The introduction of Zr can significantly improve the thermal stability of Mg/Co up to 400°C without reducing EUV reflectance. Thus, introduction of Zr barrier layer is an efficient method to improve the thermal stability of Mg/Co multilayer for EUV applications such as astronomical observation and synchrotron radiation.
Comparison of the length of hospitalization and mortality rate for people with diabetes in diabetes-certified vs. non-certified hospitals in Germany v1

Field: Health Professions (Health Sciences)

Our aim is to analyze whether the advantages of the hospitals certified by the German Diabetes Association (DDG) regarding in-hospital mortality when compared to non-certified hospitals as presented in a preprint are consistent after adjustment for several potential confounders. In particular, we want to carry out adjusted regression models to compare the length of the hospitalization and the mortality rate for people with diabetes in certified vs. non-certified hospitals.
The Functional Role of Human 2B4 (CD244( Isoforms in Natural Killer Cells

Field: Immunology and Microbiology (Life Sciences)

Rao, Krithi K., Functional role of human 2B4 (CD244) isoforms in natural killer cells. Master of Science (Immunology), July, 2007, 66 pp., 15 illustrations, bibliography. Natural killer (NK) cells are a subpopulation of lymphoctyes that play an important role against tumor metastasis and various viral and bacterial infections. NK cell functions are controlled by a balance between positive and negative signals through various receptors. We have identified, cloned, and characterized the 2B4 (CD244) receptor in mice and human. 2B4 is involved in killing cancer cells and virus-infected cells by NK cells. 2B4 is involved in killing cancer cells and virus-infected cells by NK cells. 2B4 is a counter-receptor for CD48 and recent findings show that 2B4-CD48 interactions plan an important role in NK, T and B cell functions. In humans, two isoforms of 2B4, h2B4-A and h2B4-B, are expressed that differ in the extracellular domain. In the present investigation, we have studied the functions of h2B4-A and h2B4-B. Our data demonstrate that these two isoforms differ in their binding affinity for CD48, resulting in differential cytolytic function as well as cytokine production by NK cells. Thus, differential expression of 2B4 isoforms by NK cells may regulate immune responses mediated through 2B4-CD48 interactions.
Contributions of Anthropology and Sociology to Alcohol Epidemiology

Field: Social Sciences (Social Sciences)

Abstract Culturally speaking, alcohol is not a neutral topic. As far as is known, all contemporary societies have knowledge of alcohol, either through their own fermentation and distilling techniques, or through contact with areas where alcoholic beverages are produced. Yet groups of people bound together by a shared belief system and a common cultural heritage often hold distinctive views about drinking (Marshall, 1979; Heath, 1986a, 1986b). Among some groups, the use of alcohol is highly valued for the ideologic and integrative role it plays in religious ceremonies and social festivals. Among others, its use is severely proscribed and sometimes legally prohibited.
Optimization practical SCARA robot trajectory based on a linear quadratic controller

Field: Engineering (Physical Sciences)

SCARA (Specific consistent enunciated robot arm) comprises of three planar revolute joints as shoulder, elbow and wrist and a kaleidoscopic joint which works in vertical plane for legitimate situating of the work piece. It offers particularly a decent decision for get together errands. A wide range of studies are seen on displaying and control of SCARA type robot to get high precise direction in industrial and biomedical application. Direct quadratic controller with Gaussian (LQG-controller) models of the movement and detecting vulnerability, as it gives ideal control to managing a robot along an arranged way. For straight elements and perception models with Gaussian commotion and a quadratic cost work, the ideal methodology for executing the way is to utilize a LQR input controller in corresponding with a Kalman channel for state estimation, which is called direct quadratic Gaussian (LQG) control. A Kalman channel gives the ideal gauge of the state given past state evaluations, estimations and control inputs, and a LQR controller gives the ideal control input given the gauge of the state. This paper exhibits another way to deal with SCARA robot movement arranging that considers the sensors and the controller that will be utilized during execution of the robot’s way. LQG depends on the straight quadratic controller with Gaussian models of vulnerability and expressly portrays ahead of time from the earlier likelihood dispersions of the condition of the robot along its way.
In Reply: Was This Experiment Necessary?

Field: Medicine (Health Sciences)

The issue of neonatal research is so charged with emotion that it can apparently cause a reader to pick up his pen to write a letter of criticism without having read carefully the report which he is criticizing. We are rebuked for subjecting newborn infants to numerous venipunctures though we stated clearly that no venipunctures at all were done for investigational purposes. The single reported serum bilirubin determination per subject was made as part of the routine neonatal care and involved the withdrawal of a very small volume of blood by heel-prick.
Superlubricity enabled dry transfer of non-encapsulated graphene

Field: Materials Science (Physical Sciences)

Transferring high-quality exfoliated graphene flakes onto different substrates while keeping the graphene free of polymer residues is of great importance, but at the same time very challenging. Currently, the only feasible way is the so-called all-dry pick-and-lift method, in which a hexagonal boron nitride (hBN) flake is employed to serve as a stamp to pick up graphene from one substrate and to lift it down onto another substrate. The transferred graphene samples, however, are always covered or encapsulated by hBN flakes, which leads to difficulties in further characterizations. Here, we report an improved pick-and-lift method, which allows ultra-clean graphene flakes to be transferred onto a variety of substrates without hBN coverage. Basically, by exploiting the superlubricity at the graphene/hBN stack interface, we are able to remove the top-layer hBN stamp by applying a tangential force and expose the underneath graphene.
Research on the Clarification Technology of Prunus humilis Juice

Field: Agricultural and Biological Sciences (Life Sciences)

[Objective] The aim was to provide theoretical basis for improving and screening the clarification technology of Prunus humilis juice.[Method] The P.humilis juice was clarified by 3 methods of enzymatic hydrolysis with pectinase,precipitation with chitosan and ultrafiltration resp.so as to research the clarification technology of P.humilis juice.[Result] The results of range analysis showed that the effects of enzymatic hydrolysis conditions of pectinase on the clarity of juice were as follows: enzymatic hydrolysis temperature pectinase concn. enzymatic hydrolysis time;that of precipitation conditions of chitosan on the clarity of juice were as follows: chitosan dosage precipitation temperature precipitation time;that of ultrafiltration conditions on the clarity of juice were as follows: outlet pressure temperature inlet pressure.The results of orthogonal test showed that the optimum technological condition for clarifying juice with pectinase was enzymatic hydrolysis with 0.04% pectinase at 50 ℃ for 1 h;that of clarifying juice with chitosan was precipitation with 0.03% chitosan at 50 ℃ for 1 h;that of clarifying juice by ultrafiltration method was setting ultrafiltration temperature at 40 ℃,inlet pressure at 0.4 MPa and outlet pressure at 0.3 MPa.[Conclusion] The research supplied good technical support for the industrialized production of P.humilis juice.
FINANCIAL LITERACY FACTORS: REGIONAL ASPECT

Field: Economics, Econometrics and Finance (Social Sciences)

Урядова Олеся Александровна, Южно-Уральский государственный университет (г. Челябинск), lesya.uryadowa@yandex.ru Жданова Нина Викторовна, Южно-Уральский государственный университет (г. Челябинск), zhdanovanv@susu.ru Olesya A. Uryadova, South Ural State University, Chelyabinsk, lesya.uryadowa@yandex.ru Nina V. Zhdanova, South Ural State University, Chelyabinsk, zhdanovanv@susu.ru
A possible legal framework for the exploitation of natural resources by non-State armed groups

Field: Social Sciences (Social Sciences)

Abstract The law of belligerent occupation permits the Occupying Power to administer and use the natural resources in the occupied territory under the rules of usufruct. This provision has no counterpart in the provisions of humanitarian law applicable to non-international armed conflicts, which may suggest that any exploitation of natural resources by non-State armed groups is illegal. The International Committee of the Red Cross's updated 2020 Guidelines on the Protection of the Environment in Armed Conflict did not touch on this issue, and nor did the International Law Commission in its 2022 Draft Principles on the Protection of the Environment in Relation to Armed Conflicts, where it applied the notion of sustainable use of natural resources instead of usufruct. The present paper aims to fill this gap. It first reviews the development of the concept of usufruct and then studies whether the current international law entitles non-State armed groups with de facto control over a territory to exploit natural resources. By delving into the proposals raised by some commentators to justify such exploitation for the purpose of administering the daily life of civilian populations, the paper advocates for a limited version of this formula as the appropriate lex ferenda . In the final section, the paper discusses how situations of disaster, as circumstances which may preclude the wrongfulness of the act, may justify the exploitation of natural resources by non-State armed groups in the current international legal order.
Six-phase Voltage Forming Method using the Largest Magnitude Space Vectors

Field: Engineering (Physical Sciences)

In this paper, a six-phase voltage source inverter with a single-neutral star connected load is investigated. A space vector PWM (SVPWM), which uses largest magnitude vectors is proposed and implemented. Simulation results of the six-phase voltage source inverter (VSI), which uses the proposed SVPWM method, are compared to the results when a standard sinusoidal PWM scheme is used. Analysis of the results shows that proposed SVPWM scheme is suitable to form a six-phase sinusoidal output voltage. The main advantage of proposed SVPWM scheme is that it requires the same computational resources as the three-phase SVPWM. DOI: http://dx.doi.org/10.5755/j01.eee.19.10.5904
INTESTINAL METABOLISM OF FRUCTOSE

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract. The metabolism of fructose by the small intestine can be analyzed in terms of the following scheme: 1) hydrolysis of fructose containing saccharides especially sucrose; 2) movement of fructose into the intestinal cell; 3) transformation of fructose into glycolytic metabolic intermediates; 4) formation of fructose from glucose via sorbitol; 5) adaptive regulation of fructose metabolizing enzymes; 6) adaptive responses of other enzymes to fructose. The hydrolysis of sucrose is dependent upon the brush border enzyme sucrase which shows an adaptive response to sucrose diets. The entrance of fructose into the small intestine and the intermediary metabolism of fructose is reviewed. Fructose metabolizing enzymes, fructokinase and fructose‐1‐phosphate aldolase, are regulated by the presence or absence of fructose, folic acid and drugs. Fructose causes adaptive changes in small intestine glycolytic enzymes and decreases the gluconeogenic enzyme fructose‐1,6‐diphosphatase. Actinomycin D inhibits the adaptive effect of fructose on glycolytic enzymes which suggests that fructose acts via the protein synthetic mechanism.
Cervical vestibular evoked myogenic potentials and video head impulse test in Ménière disease

Field: Medicine (Health Sciences)

Abstract Introduction: Ménière's disease is among the most frequent causes of vestibular disorders. Although it is a clinical diagnosis, a better understanding of the pathophysiology and clinical course of the disease through tests would allow improvement in the prognosis and more effective treatments. Objectives: To describe the results of the cervical vestibular evoked myogenic and video head impulse test in patients with a defined diagnosis of Ménière's disease and to correlate them with disease duration. Methods: The sample consisted of 50 participants, of whom 29 comprised the study group and 21 the control group. The individuals were submitted to a questionnaire, otoscopy, audiometry and vestibular function assessment through the cervical vestibular evoked myogenic potential and video head impulse test. Results: For the video head impulse test, lateral canal gain values below 0.77 were considered abnormal and for the vertical channels, below 0.61. The percentages of normality were 82.76% for lateral, 89.65% for posterior and 91.37% for anterior canals. For the cervical vestibular evoked myogenic potential, the upper limits of normal for latencies were defined as 18.07 ms for p13 and 28.47 ms for n23; and in the SG, 19.57% showed prolongation of latency of p13 and 4.35% of wave n23, whereas 18.96% did not show biphasic potential. Conclusions: For the video head impulse test, a decreased gain of the vestibulo-ocular reflex for the lateral canal was observed, with a higher incidence of overt type corrective saccades compared to the control group. For the cervical vestibular evoked myogenic potential, there was a significant difference between the groups for the inter-amplitude parameter, including for asymptomatic ears. There was no correlation between the results of the tests and disease duration.
The Role of Aryl Hydrocarbon Receptor in Bone Biology

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, is crucial in maintaining the skeletal system. Our study focuses on encapsulating the role of AhR in bone biology and identifying novel signaling pathways in musculoskeletal pathologies using the GEO dataset. The GEO2R analysis identified 8 genes (CYP1C1, SULT6B1, CYB5A, EDN1, CXCR4B, CTGFA, TIPARP, and CXXC5A) involved in the AhR pathway, which play a pivotal role in bone remodeling. The AhR knockout in hematopoietic stem cells showed alteration in several novel bone-related transcriptomes (eg, Defb14, ZNF 51, and Chrm5). Gene Ontology Enrichment Analysis demonstrated 54 different biological processes associated with bone homeostasis. Mainly, these processes include bone morphogenesis, bone development, bone trabeculae formation, bone resorption, bone maturation, bone mineralization, and bone marrow development. Employing Functional Annotation and Clustering through DAVID, we further uncovered the involvement of the xenobiotic metabolic process, p450 pathway, oxidation-reduction, and nitric oxide biosynthesis process in the AhR signaling pathway. The conflicting evidence of current research of AhR signaling on bone (positive and negative effects) homeostasis may be due to variations in ligand binding affinity, binding sites, half-life, chemical structure, and other unknown factors. In summary, our study provides a comprehensive understanding of the underlying mechanisms of the AhR pathway in bone biology.
Understanding Digital Narratives of Black Girlhood Through Social Media Aesthetics

Field: Arts and Humanities (Social Sciences)

Abstract Today, Black girls use social media, including TikTok, as sites for storytelling and for creating their own self-definitions. In this article, I address the question of how Black girls use social media aesthetics to construct digital narratives about their Black girlhoods. To do so, by analyzing a case study of TikToks, I explore the rise of the Soft Black Girl aesthetic and its connections to larger, white-dominated aesthetics, such as Cottagecore. Furthermore, I trace the political implications of social media sub-aesthetics that Black girls create, as well as how such sub-aesthetics are used to both deconstruct stereotypes pertaining to the adultification of Black girls and disengage from whiteness in online spaces.
The Sterilization and Anti-Oxidation Properties of Concentrated Duck Soup

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

This paper studies the antibacterial action of Nisin and potassium sorbate compound in concentrated duck soup,inhibit spores and other heat-resistant bacteria in the soup by adding Nisin,which reduce sterilization intensity;TBHQ,BHA and BHT were added in the soup to research the anti-oxidant effect.The results showed that:when the concentration of Nisin and potassium sorbate were 0.20 g/kg and 0.03 g/kg,sterilization conditions reduced to 115℃for 30 min;The best compound scheme of anti-oxidant is:0.15 g/kg TBHQ+0.05 g/kg BHA.
Adsorptive removal of pentachlorophenol from aqueous solutions using powdered eggshell

Field: Environmental Science (Physical Sciences)

Abstract The usefulness of untreated powdered eggshell as low-cost adsorbent for the removal of pentachlorophenol (PCP) from aqueous solutions was investigated. The most important parameters affecting the adsorption process, including the pH and ionic strength, were examined. The adsorption characteristics of PCP onto eggshell were evaluated in terms of kinetic and equilibrium parameters. The kinetic data were studied in terms of the pseudo-first order, pseudo-second order and intra-particle diffusion kinetic models. The equilibrium data were analyzed using the Langmuir, Freundlich, Sips and Redlich-Peterson isotherm models. The pseudo-second order model best described the adsorption kinetics. Using the Langmuir equation, the monolayer adsorption capacity of eggshell for PCP was found to be 0.127 mg/g. The results showed that PCP can be effectively removed from aqueous solution employing eggshell as a cheap adsorbent.