jimnoneill/paper-to-field-training huggingface dataset:
Same Voices, Other Tombs: Structures of Mexican Gothic

Field: Arts and Humanities (Social Sciences)

The new Gothic may be explained in part as a consequence of a transition from an analogical to a metaphorical relationship between the corporeal and transcendent spheres of human experience. Irving Malin and, in a related effort, J. Douglas Perry delineate certain categories of themes, images, and narrative structures which define "new American Gothic" in contemporary fiction. Departing from Northrop Frye's observation that archetypes are basically a problem of structure rather than historical origin, and, that there may be archetypes of genres as well as of images, the present essay attempts to decipher certain paradigmatic categories and structures which reveal the presence of the Gothic genre in the contemporary Mexican novel. Carlos Fuentes' La muerte de Artemio Cruz and Juan Rulfo's Pedro Páramo serve as the source of the categories delineated in this study.
Rabbit Precipitin Antibody to Chicken Erythrocyte Histone F2C

Field: Immunology and Microbiology (Life Sciences)

Abstract Specific precipitin antibody was induced in rabbits to a pure preparation of the chicken erythrocyte histone F2C. The hyperimmune sera obtained reacted in agarose gel to form a distinct precipitin line with about 1 µg of F2C. No cross-reactivity could be detected with whole histone or histone fractions F1, F2B, F2A1, F2A2 and F3 isolated from calf or chicken thymus. The nonspecific precipitation between all histone fractions and normal serum proteins was completely removed by absorption of the hyperimmune sera with calf or chicken thymus whole histone or the various histone fractions. The specificity of the immune reaction against F2C was also proved by the skin test which was strongly positive in all the rabbits that had developed precipitin antibody. Chicken erythrocyte specific histone F2C was found to be antigenically distinct from any other histone fraction.
Digital Deception: An In-Depth Investigation of Identity Theft in the Indian Cyberspace

Field: Social Sciences (Social Sciences)

The article delves into the growing problem of cyber identity theft in India, acutely challenging the nation that is the world's fastest-growing digital economy with a consistent increase in the number of internet users.It examines the legal framework given by the Information Technology Act 2000 and Indian Penal Code that facilitates punishing cyber identity theft crimes.It analyses some prominent cases that provide insights into the multifaceted consequences of cyber identity theft, such as financial losses, mental trauma, public scorn and so on.It also deciphers the vulnerabilities such types of crimes pose for agencies and law enforcement and the problems in curbing them, such as legal hindrances, jurisdiction issue and publicity.It sheds light on the global practices of dealing with such crimes and recommends the improvement in Indian laws and cyber security measures by comparing it with other countries.In conclusion, it reflects upon the dynamic nature of cyber identity theft and the need for India leading and cooperating among other countries in curbing this menace.
Secondary Metabolites from Eupenicillium parvum and Their in Vitro Binding Affinity for Human Opioid and Cannabinoid Receptors

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Phytochemical investigation of the soil microfungus Eupenicillum parvum led to the isolation of two new compounds: a chromone derivative euparvione (1) and a new mycophenolic derivative euparvilactone (2), as well as thirteen known compounds. The structures of the new compounds were elucidated by means of extensive IR, NMR, and MS data and by comparison of data reported in the literature. The structure of the known compound 6 was confirmed by X-ray crystallography. Several isolated compounds were evaluated for in vitro binding assays using opioid receptors (subtypes δ, κ, and µ) and cannabinoid receptors (CB1 and CB2). Compound 10 displayed the best selective µ-opioid receptor and CB1 receptor binding affinities showing values of 47% and 52% at a 10 µM concentration, respectively. These findings provide insight into the potential therapeutic utility of this class of compounds.
Solid-Phase Enzyme Immunoassay for the Detection of HMG Nonhistone Proteins in Their Native Structure

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract The use of purified specific antibodies against HMG1 and HMG17 (high mobility group nonhistone chromosomal proteins), together with a very sensitive solid phase enzyme immunoassay, allows the detection of nanograms of these proteins free in solution or in chromatin native structure, and the measurement of their accesibility. The sensitivity of the assay is comparable to that of the radioimmunoassay. With the advantage of avoiding the handling of radioactive materials.
Discovery of /sup 260/Md and the decay properties of /sup 258/Fm, /sup 258m,g/Md, and /sup 259/Md

Field: Physics and Astronomy (Physical Sciences)

We have discovered a new neutron-rich isotope, /sup 260/Md, from /sup 18/O and /sup 22/Ne bombardments of /sup 254/Es. We observed a spontaneous-fission (SF) activity with a 32-day half-life in electromagnetically separated mass-260 fractions from these bombardments and we have measured the mass and kinetic energy distributions of this SF activity. The mass distribution was symmetric with the principal energy peak at 234-MeV total kinetic energy (TKE), similar to previous observations for heavy Fm isotopes. Surprisingly, we also observed a smaller symmetric component with 195-MeV TKE. We interpret these two peaks in the TKE distribution as arising from two types of fission in the same nucleus, or bimodal fission. The observed fission activity may be either from the SF decay of /sup 260/Md or /sup 260/Fm which would arise from electron capture (EC) decay of /sup 260/Md. We have eliminated the possible ..beta../sup -/ decay of /sup 260/Md by measuring ..beta../sup -/-SF time correlations for the decay of /sup 260/Md and we plan to determine if /sup 260/Md decays by EC by measuring time correlations between Fm x-rays and SF events. We also measured properties for heavy Fm and Md isotopes which include: (1) more accurate cross sections for the neutron-rich Md isotopes which we use to predict the production rates of yet undiscovered nuclides; (2) improved half-live measurements for /sup 258m,g/Md and /sup 259/Md; (3) confirmation of the EC decay of /sup 258m/Md by measuring Fm x-rays preceding the SF decay of /sup 258/Fm; and (4) very substantially improved mass and TKE distributions for the SF decay of /sup 258/Fm and /sup 259/Md.
Genetic Assessment of Oil Contributing Traits in Upland Cotton

Field: Agricultural and Biological Sciences (Life Sciences)

Cotton is the most important fiber as well as oil crop around the globe and plays a vital role in the economy of Pakistan. Present research work was planned to evaluate 5 parents along with their 20 hybrids of upland cotton for oil content and oil contributing traits in a complete diallel fashion in randomized complete block design with three replications. Genetic variance, phenotypic variance, environmental variance, heritability and correlation was estimated for various morphological traits. Results revealed that parent AA-802 and exhibited good performance for sympodial branches per plant, number of bolls per plant, boll weight, ginning outturn (GOT) seed index, lint index and seed cotton yield. Whereas, C-26 identified as better performer exclusively for plant height, sympodial branches per plant, seed index and oil contents. Cross SB-149 × C-26 showed significant response for seed cotton yield, sympodial branches per plant, boll weight, number of bolls per plant, plant height, seed index, lint index, seed cotton yield and oil contents. SB-149 × AA-802 presented better results for the traits namely, sympodial branches per plant, boll weight, GOT, seed index and seed cotton yield. High heritability estimate was recorded in boll weight, number of bolls per plant, GOT, oil contents while moderate heritability was estimated in seed cotton yield, lint index and seed index. Low heritability was estimated in plant height and sympodial branches. These identified parents and hybrids could be used in future breeding programs to overcome the oil-related problems in upland cotton.
Potentiometric Detection of Listeria monocytogenes via a Short Antimicrobial Peptide Pair-Based Sandwich Assay

Field: Chemistry (Physical Sciences)

Peptide-based sandwich assays are promising tools in molecular detection, but may be restricted by the availability of "pairs" of affinity peptides. Herein, a new potentiometric sandwich assay for bacteria based on peptide pairs derived from an antimicrobial peptide (AMP) ligand is demonstrated. As a model, the original AMP with a well-defined structure for Listeria monocytogenes (LM) can be split into two fragments to serve as the peptide pairs for the sandwich assay. The recognition and binding of the short peptide pairs to the target can be verified by circular dichroism, flow cytometry, fluorometry, and optical microscopy. The potentiometric magnetic bead-based sandwich assay is designed by using horseradish peroxidase as a label. The enzyme can catalyze the oxidation of 3,3',5,5'-tetramethylbenzidine with H2O2 to induce a potential change on a polymeric membrane ion-selective electrode. Under optimal conditions, the concentration of LM can be determined potentiometrically in a linear range of 1.0 × 102 to 1.0 × 106 CFU mL-1 with a detection limit of 10 CFU mL-1 (3σ). The proposed sensing strategy expands the applications of peptides in the field of bioassays.
Family Care Partners and Paid Caregivers: National Estimates of Role-Sharing in Home Care

Field: Health Professions (Health Sciences)

Abstract Background and Objectives We describe “role-sharing” in home care, defined as family care partners and paid caregivers assisting with the same task(s). Research Design and Methods We studied 440 participants in the 2015 National Health and Aging Trends Study receiving paid help with self-care, mobility, or medical care. We describe patterns in receiving paid help only, help from care partners only, and role-sharing. We examine whether sole reliance on paid help or role-sharing differs by Medicaid-enrollment and dementia status. Results Half (52.9%) of care networks involved role-sharing. Care networks involving role-sharing more often occurred among older adults with dementia (48.7% vs 25.6%, p &lt; .001) and less often for those who were Medicaid-enrolled (32.1% vs 49.4%, p &lt; .01). Those living with dementia more often experienced role-sharing in eating (odds ratio [OR] 3.9 [95% confidence interval {CI} 1.20, 8.50]), bathing (OR 2.7, [95% CI 1.50, 4.96]), dressing (OR 2.1 [95% CI 1.14, 3.86]), toileting (OR 2.9 [95% CI 1.23, 6.74]), and indoor mobility (OR 2.8 [95% CI 1.42, 5.56]), and less often received help solely from paid helpers with medication administration (OR 0.24, [95% CI .12, .46]). Medicaid-enrollees more often received paid help only in dressing (OR 2.0 [95% CI 1.12, 3.74]), outdoor (OR 2.4 [95% CI 1.28, 4.36]), and indoor mobility (OR 4.3 [95% CI 2.41, 7.62]), and with doctor visits (OR 2.8 [95% CI 1.29, 5.94]). Discussion and Implications Role-sharing is common, especially among older adults living with dementia who are not Medicaid-enrolled. Strategies supporting information sharing and collaboration in home-based care merit investigation.
PENGHAPUSAN PRESIDENTIAL THRESHOLD SEBAGAI UPAYA PEMULIHAN HAK-HAK KONSTITUTIONAL

Field: Social Sciences (Social Sciences)

The removal system of the presidential threshold had a positive impact on the development of Indonesian democracy. The system had restored the remedy of constitutional rights that was torn by the presidential threshold. Non-majority parties obtained many advantages: to propose their respective president candidates and to add choices in the presidential election. The presidential thresholds eased the president in conducting government duties because of not being intervened by the other dominant parties in the parliament. However, the weakness of this removal system needed to be considered, for example, the vulnerability of individual interests gained through presidential candidacy. It might also expand the conflict escalation and election crime due to a large number of candidates based on the national security aspect. The other weakness was increasing the election budget allocation referring to the efficiency aspect. The budget allocation would be beneficial to share with other departments in improving people’s welfare. However, further study about the campaign and its efficiency should be conducted to prove the assumptions. Abstrak: Penghilangan sistem presidential threshold (ambang batas) di satu sisi telah berdampak positif untuk perkembangan demokrasi Indonesia. Sistem ini dapat memulihkan hak-hak dasar warga dalam konstitusi (remedy of constitutional rights) yang pernah dilukai dengan adanya presidential threshold. Banyaknya manfaat yang akan didapat oleh partai-partai bukan mayoritas agar bisa mengusulkan calon presidennya masing-masing, dan juga membuat pilihan presiden pun makin beragam. Dengan adanya PT akan lebih mempermudah presiden untuk melaksanakan tugas pemerintahan, disebabkan tidak terjadinya intervensi partai lainnya yang dominan dalam parlemen. Namun demikian kelemahan dari penghapusan PT juga patut untuk dipertimbangkan, seperti rentannya kepentingan individu yang bisa diperoleh melalui pencalonan presiden. Dari aspek keamanan nasional akan berakibat pada perluasan eskalasi konflik dan tindak pidana pemilu disebabkan banyaknya kandidat. Dari segi efisiensi, alokasi anggaran pemilu akan semakin membengkak (high cost election). Setidaknya alokasi dana pemilu dapat di salurkan ke bidang-bidang yang dapat meningkat kesejahteraan rakyat lainnya. Akan tetapi asumsi ini perlu dibuktikan lebih lanjut dengan riset mendalam tentang efisiensi dana kampanye. Kata Kunci: presidential threshold, remedy of constitutional rights, high cost election
COPYRIGHT © 2005 BY THE JOURNAL OF BONE AND JOINT SURGERY, INCORPORATED Molecular and Immuno- histological Characterization of Human Cartilage Two Years Following Autologous

Field: Medicine (Health Sciences)

Background: There are only a few studies concerning the cellular, biochemical, and genetic processes that occur during the remodeling of graft tissue after autologous chondrocyte transplantation. The purpose of the present study was to quantify the expression of genes encoding extracellular matrix proteins and regulatory factors that are essen-tial for cell differentiation in cartilage biopsy specimens from patients who had this treatment two years previously. Methods: Two cartilage biopsy specimens from each of four patients who had been treated with autologous chondro-cyte transplantation and from two multiorgan donors were used. Real-time reverse transcriptase-polymerase chain reac-tion analysis was performed to evaluate the expression of types I, II, and X collagen; aggrecan; cathepsin B; and early growth response protein-1 (Egr-1) and Sry-type high-mobility-group box transcription factor-9 (Sox-9) mRNAs. Immunohis-tochemical analysis for matrix proteins and regulatory proteins was carried out on paraffin-embedded sections. Results: Type-I collagen mRNA was expressed in all of the samples evaluated. Type-II collagen was present in autolo-gous chondrocyte transplantation samples but at lower levels than in the controls. Type-X collagen messenger was undetectable. Aggrecan mRNA was present in all of the samples at lower levels than in the controls, while cathepsin-B messenger levels were higher and Egr-1 and Sox-9 mRNAs were expressed at lower levels. The immunohistochemi-cal analysis showed slight positivity for type-I collagen in all of the sections. Type-II collagen was found in all of the samples with positivity confined inside the cells, while the controls displayed a positivity that was diffuse in the extra-
Research and Discussions on the Evaluation of Chinese Teaching Materials under the Perspective of Deaf Students---A Case Study of Deaf Students in Grade 5 of Deaf Schools in Xi'an and Guang Dong

Field: Social Sciences (Social Sciences)

From the investigation, we found out that most of the deaf students think the Chinese textbook of general school are much more difficult than the deaf school's and they show a lower favor to them. By comparing the aspects of literacy, the text length and the illustration of the two editions of textbooks, we found that the deaf students' Chinese textbook is not clear enough to allow the deaf students to completely understand because of its own way to teach, the teaching materials' selection, and the students’learning support. So on the basis of this, I suggest that we improve the deaf students' textbook based on their abilities to learn and to understand and also improve the language learning support system. Then we can publish the deaf school's curriculum standards by compiling a new Chinese textbook with a better understanding of deaf students.
Why do Pre-Service Teachers Pose Multiplication Problems Instead of Division Problems in Fractions?

Field: Arts and Humanities (Social Sciences)

The aim of this study was to investigate pre-service elementary mathematics teachers' problem types which were posed for modeling fraction division. Data was collected from pre-service elementary mathematics teachers in the spring semester of 20102011 who were enrolled in a teacher education program at a public university. Data collection tool entailed pre-service elementary teachers posing world division problems corresponding to the fractions written in symbolic form. The results of the study revealed that pre-service elementary mathematics teachers posed problems involving fraction multiplication rather than fraction division and they used invert and multiply algorithm. There was evidence that they did not have adequate learning about fraction division.
Elizabethan Satire and the Bishops' Ban of 1599

Field: Arts and Humanities (Social Sciences)

Satyres tearmed Halls Satyres, viz' Virgidemiarum, or his tootheles or bitinge Satyres / Pigmalion with certaine other Satyres / The scourge of villanye / The Shadowe of truthe in Epigrams and Satyres / Snarlinge Satyres / Caltha Poetarum / Davyes Epigrams, with marlowes Elegyes / The booke againste woemen, viz'; of marriage and wyvinge / The xv ioyes of marriage / That noe Satyres or Epigramms be printed hereafter That noe Englishe historyes bee printed excepte they bee allowed by somme of her majesties privie Counsell / That noe playes bee printed excepte they bee allowed by suche as have aucthorytie / That all nasshes bookes and D Harvyes bookes be taken wheresoever they maye be found and that none of theire bookes bee ever printed hereafter / That thoughe any booke of the nature of theise heretofore expressed shalbe broughte unto yow under the hands of the Lord Archbisshop of Canterburye or the Lord Bishop of London yet the said booke shall not bee printed untill the master or wardens have acquainted the said lord Archbishop, or the Lord Bishop with the same, to knowe whether it be theire hand or no / John cantuar / Richard London Suche bookes as can be found or are allready taken of the Argumentes aforesaid or any of the bookes above expressed lett them bee presentlye broughte to the Bishop of London to be burnte /1
Assessing the influence of aneurysm dimensions on hemodynamic patterns and wall deformation dynamics for predicting rupture risk

Field: Medicine (Health Sciences)

Cerebral aneurysms are among the most dangerous cardiovascular diseases which display no symptoms prior to reaching critical conditions. As cerebral aneurysms are deadly diseases with a very small treatment window after reaching the critical stage, numerical investigations of this phenomenon are commonly used to assess the risk of rupture. In this study, the fluid-structure interaction (FSI) method is used to analyze the effects of aneurysm size on hemodynamic factors predicting rupture in three aneurysms of different geometries, at the same location, and using the same boundary conditions. In the present study, the aneurysms experience TAWSS at values under 2 Pa in incremented areas as the aneurysmal sizes increase, this is while the relatively larger distribution of high TAWSS (as high as 20 Pa) regions are perceived in smaller aneurysms. Furthermore, the maximum OSI stands at below 0.05 in the smaller cases while the larger case experiences a maximum OSI as high as 0.2, which is considered a predictive parameter for rupture. The vortex core lines experience discontinuities with increased aneurysmal size, which is in agreement with the development of flow complexities with size. The hemodynamics factors such as the time-averaged wall shear stress (TAWSS), oscillatory shear index (OSI), and vortex core line investigated in this study, suggest that greater size can be considered a major risk factor for rupture. In addition to that, we have found that the displacement trend of the aneurysm changes as size increases; developing more in the dome rather than the aneurysmal sac. This change in trend might also present a potential to be used as a predictive parameter.
Study of the kinetics of sorption of heavy metal ions by dry biomass of cyanobacteria

Field: Environmental Science (Physical Sciences)

Sorption of copper (II), lead (II) and cadmium ions from a solution with a concentration of 1 ∙ 10-4 mol/L by dry biomass of cyanobacteria Fischerella muscicola occurred 1.4-1.9 times faster than Nostoc paludosum. The sorption rate of lead and copper ions was 1.9-2.6 times higher compared to cadmium ions.
Innovative Trial Approaches in Immune-Mediated Inflammatory Diseases: Current Use and Future Potential

Field: Medicine (Health Sciences)

Abstract Background: Despite progress that has been made in the treatment of many immune-mediated inflammatory diseases (IMIDs), there remains a need for improved treatments. Randomised controlled trials (RCTs) provide the highest form of evidence on the effectiveness of a potential new treatment regimen, but they are extremely expensive and time consuming to conduct. Consequently, much focus has been given in recent years to innovative design and analysis methods that could improve the efficiency of RCTs. In this article, we review the current use and future potential of these methods within the context of IMID trials. Methods: We provide a review of several innovative methods that would provide utility in IMID research. These include novel study designs (adaptive trials, Sequential Multi-Assignment Randomised Trials, basket, and umbrella trials) and data analysis methodologies (augmented analyses of composite responder endpoints, using high-dimensional biomarker information to stratify patients, and emulation of RCTs from routinely collected data). IMID trials are now well-placed to embrace innovative methods. For example, well-developed statistical frameworks for adaptive trial design are ready for implementation, whilst the growing availability of historical datasets makes the use of Bayesian methods particularly applicable.To assess whether and how these innovative methods have been used in practice, we conducted a review via PubMed of clinical trials pertaining to any of 51 IMIDs that were published between 2018-20 in five high impact factor clinical journals. Results: Amongst 97 articles included in the review, 19 (19.6%) used an innovative design method, but most of these were relatively straightforward examples of innovative approaches. Only two (2.1%) reported the use of evidence from routinely collected data, cohorts, or biobanks. Eight (9.2%) collected high-dimensional data. Conclusions: Application of innovative statistical methodology to IMID trials has the potential to greatly improve efficiency, to generalise and extrapolate trial results, and to further personalise treatment strategies. Currently, such methods are infrequently utilised in practice. New research is required to ensure that IMID trials can benefit from the most suitable methods.