jimnoneill/paper-to-field-training huggingface dataset:
The domestic livestock resources of Turkey: cattle local breeds and types and their conservation status

Field: Agricultural and Biological Sciences (Life Sciences)

Turkey's 10.6 million head of cattle comprise a rich array of native breeds and types but these are being increasingly eroded by the often indiscriminate use of exotic genotypes. The structure of agriculture is such that most farms are predominantly subsistence oriented, of small size, keep few animals and provide only minimal inputs. Native breeds have evolved to meet these conditions and are generally well adapted to the natural environment, inadequate and unbalanced nutrition and disease stress. In the last 80 years, there has been much modification of the natural gene pool and many distinct breed types are in danger of or have already suffered extinction. This paper describes some of the major remaining cattle genetic resources and their conservation status. Government is now aware of the danger of the impoverishment or loss of this important aspect of biodiversity and has established programmes for conservation and preservation of several native breeds. Government, research institutions and producers should work together to ensure that the local gene pool is preserved and can thus continue to contribute to biodiversity and sustainable livestock production.
Application of automatic cleaning & disinfection sterilizer in initially treating infected medical instruments.

Field: Health Professions (Health Sciences)

OBJECTIVE To explore the safety of automatic cleaning disinfection sterilizer for the initial treatment of infected and special infected medical instruments so as to improve the staffs′ personal protection and reduce cross infection.METHODS The medical articles and instruments used in the clinic and operations were collected and put into the automatic cleaning disinfection sterilizer for cleaning and sterilizing in turn.RESULTS Total 444 301 sets of infected and special infected medical instruments have been rinsed,disinfected,sterilized and evacuatied from 2006 to 2008 years.The qualified ratio of the germ killed in cleaning was 100.0% in all three years.CONCLUSIONS The DPX automatic controlled cleaning disinfection sterilizer can not only improve the cleaning quality and ensure the sterilization effect,but also reduce cross infection.
Quantum Computing and Machine Learning for Efficiency of Maritime Container Port Operations

Field: Computer Science (Physical Sciences)

Maritime container ports are experiencing a variety of challenges, including the pandemic and other stressors, that are altering perspectives on efficiency, risk, and resilience. This study reviews new methods of operations optimization that serve major goals of logistics systems: Increasing energy and time efficiencies and reducing emissions and congestion. Several computational methods will be assessed, including quantum computing, neural networks, and operations heuristics. The methods are compared by potential for increased efficiencies, including the increase in container volumes, reduction of dwell times, reduction of container moves, utilization of demand forecasts, and decreases in emissions. The results suggest opportunities for reinforcement learning to improve the scheduling of container transactions across transportation modes, including maritime, truck, rail, crane, and barge.
Abstract 4738: Dysregulated miR-371b-5p/CSDE1/RAC1 axis is involved in pathogenesis of triple-negative breast cancer

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer; however, pathogenesis of TNBC has not yet been fully understood. Here, we identified dysregulated microRNAs (miRNAs) by analyzing miRNA microarray of TNBC patients. MiR-371b-5p expression was reduced, and ectopic expression of miR-371b-5p significantly inhibited TNBC progression in vitro and in vivo. In addition, we found that expression of cold shock domain-containing protein E1 (CSDE1), a direct target gene of miR-371b-5p, was upregulated in TNBC cells, and inhibition of CSDE1 alleviated TNBC cell growth by decreasing RAC1 known as pro-metastatic gene. Mechanistically, CSDE1, phosphorylated C-terminal domain (p-CTD) of RNA polymerase II (RNAPII), and CDK7 form a complex, and downregulation of CSDE1 results in weak interaction between RNAPII p-CTD and CDK7, which leads to a decrease in RNAPII p-CTD expression to reduce RAC1 transcript levels in CSDE1-deficient TNBC cells. Our data revealed the oncogenic function of miR-371b/CSDE1 involved in Rac1 transcription regulation, thus providing a basis for the pathological mechanism of TNBC along with potential biomarkers for TNBC. Citation Format: Yesol Kim, Je Yeong Ko, Soo-Been Lee, Jaehee Jun, Yejin Ahn, Jinui Min, Chaewon Oh, Jong Hoon Park. Dysregulated miR-371b-5p/CSDE1/RAC1 axis is involved in pathogenesis of triple-negative breast cancer. [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 4738.
Enhanced Alkali Pretreatment of Narrow Leaves Cattail by Response Surface Methodology

Field: Chemical Engineering (Physical Sciences)

The purpose of this work is to develop a pretreatment process of lingo-cellulosic ethanol production from narrow leaves cattail (Typha angustifolia) by using alkali catalysis with the response surface methodology (RSM) as a central composite design (CCD). The first step, LiOH, NaOH, and KOH were used as catalytic alkali for preliminary test. Second, the suitable alkali from first step was selected to optimize of pretreatment condition of three independent variables (alkali concentration, temperature, and residence time) that varies at CCD five codes (-2, -1, 0, 1, 2). Sodium hydroxide (NaOH) is the proper alkali because it could increase cellulose more than KOH and nearby LiOH while it is cheapest. RSM result shows the optimized pretreatment condition based on cellulose increased which obtained from this study that is NaOH 5 % w/v at 100 °C and residence time for 120 min. Beside, this condition was analyzed using an ANOVA with a second order polynomial equation after eliminated non-significant terms. At the optimized conditions, cellulose increased, hemicellulose decreased and weight recovery were achieved 77.81%, 80.59, and 41.65%, respectively. Moreover, the model was reasonable to predict the response of strength with less than 5% error.
A model of adaptive links in nonlinear viscoelasticity

Field: Engineering (Physical Sciences)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Aleksey D. Drozdov; A model of adaptive links in nonlinear viscoelasticity. J. Rheol. 1 November 1997; 41 (6): 1223–1245. https://doi.org/10.1122/1.550849 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentThe Society of RheologyJournal of Rheology Search Advanced Search |Citation Search
Knowledge Construction and Uncertainty in Real World Argumentation: A Text Analysis Approach

Field: Social Sciences (Social Sciences)

Collaborative argumentation is key to promoting understanding of scientific issues. However, classroom structures may not always prepare students to engage in argumentation. To address this challenge, education researchers have examined the importance of social knowledge construction and managing uncertainty in group understanding. In this study, we explore these processes using data from /r/ChangeMyView, an online forum on Reddit where users present their opinions, engage others in critiquing ideas, and acknowledge when the discussion has modified their opinions. This unfacilitated environment can illuminate how argumentation evolves naturally towards refined opinions. We employ automated text analyses (LIWC) and discourse analyses to understand the features and discourse sequences of successful arguments. We find that argumentative threads are more likely to be successful if they focus on idea articulation, coherence, and semantic diversity. Findings highlight the role of uncertainty: threads with more certainty words are less likely to be successful. Furthermore, successful arguments are characterized by cycles of raising, managing, and reducing uncertainty, with more occurrences of evidence and idea incorporation. We discuss how learning environments can create norms for idea construction, coherence, and uncertainty, and the potential to provide adaptive prompts to maintain and reduce uncertainty when unproductive argumentative sequences are detected.
Prevalence of dementia in a Japanese population

Field: Medicine (Health Sciences)

I read with great interest the paper by Yamada et al.1 In their study, they stated that the prevalence of Alzheimer's disease (AD) was two times higher in women than in men, while vascular dementia (VD) was the same in both sexes. In their study, however, 20 out of 46 (43.5%) demented men were younger than 80 years and 41 of 142 (28.9%) demented women were younger than 80 years. They also stated that the incidence of VD might decrease as the risk of stroke decreased because the recent prevalence of VD and the incidence of stroke had decreased in the Hisayama Study.2 Since the survival rate of AD is higher compared to the rate of VD,3,4 women may have the greater prevalence of AD because they live longer than men. I would like to ask Yamada et al. to show age- and sex-specific prevalence of AD, as it may be helpful for readers to know whether women have higher age-adjusted prevalence of AD compared with men.
The Cohen-Macaulay property of affine semigroup rings in dimension 2

Field: Mathematics (Physical Sciences)

Consider the subring R=k[xa,xp1yq1,…,xptyqt,yb] of k[x,y], where k is a field and x, y indeterminates over k. We calculate the Hilbert polynomial of (xa,yb). The multiplicity of this ideal provides part of a criterion for the ring to be Cohen-Macaulay. Next, we prove a simple numerical criterion for R to be Cohen-Macaulay in the case when t = 2. We also provide a simple algorithm which identifies the monomial k-basis of R/(xa,yb). Finally, these methods are specialized to the case of projective monomial curves in P3.
Java in the Loop of Data Acquisition Systems

Field: Computer Science (Physical Sciences)

Modern Distributed Data Acquisition Systems consist of many different components. Those components can be made by different manufacturers, be based on different hardware platforms, running different software or firmware applications and implement by different hardware/software system developers. This component variety makes distributed systems to be heterogeneous at two levels: at executable code level, due to the fact that the binary code of a platform might be incompatible with other platforms; at data level, because different platforms might have different ways to represent, store and deal with data. To overcome issues raised by this platform heterogeneity it can be used a Virtual Machine technology, a Middleware technology or both technologies together. Virtual Machines present to the programmer a homogeneous development platform, therefore the programmer does not need to concern about the final platform where the application will be used. Middleware offers the tools for programmers to develop distributed applications without concerning about details of objects’ communications. Java is one of the most used Virtual Machine technologies and it has support for different platforms. Its support goes from desktop computers to mobile phones. A key point of this technology is its support for many different Operating Systems such as Microsoft Windows family, Solaris, Linux and Mac OS. Java also supports the most used Middleware technologies, allowing the implementation of distributed data acquisition systems compatible with components made with other development tools. Based on the latest trends in consumer electronics and industrial applications using WSN (Wireless Sensor Network), smart sensors and embedded systems, we can conclude that future nodes must become smarter, cheaper and smaller. So, the major challenge is to produce smart sensing devices which have very low resources. Besides that, also the reduction of both the development time and costs are needed. Considering this, two approaches can be used: in the first, hardware resources are made accessible, e.g. connecting them over TCP/IP, putting these devices at the distance of a click; the second is to give to bus-level devices some characteristics that until now are mainly found in the traditional computing systems. The second approach is based on the
Post-translational modifications of the major linear epitope 169–190aa of Ro60 kDa autoantigen alter the autoantibody binding

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Summary Ro60 kDa is a member of the Ro/LaRNP ribonucleoprotein complex and its major linear B cell epitope, corresponding to the region 169–190aa, has been found to be the initial target of the autoimmune response in patients with systemic lupus erythematosus. This sequence contains one serine and two arginine amino acid residues, which can potentially be modified post-translationally by phosphorylation or citrullination, respectively. The aim of this study was to develop an immunoassay for anti-Ro60 kDa epitope antibody detection and to investigate the changes in the antigenicity of the Ro60 kDa epitope when it is post-translationally modified, by either citrullination or phosphorylation. Peptide analogues corresponding to the unmodified form of the epitope, its phosphorylated form, and a form with both arginine residues citrullinated were synthesized. The peptide coating conditions were investigated and it was found that the use of highly hydrophilic surfaces increase the efficiency of the coating, as well as the sensitivity of the method for anti-peptide antibody detection. All peptides were tested by the optimized enzyme-linked immunosorbent assay (ELISA) against 119 sera from patients with primary Sjögren's syndrome, systemic lupus erythematosus and rheumatoid arthritis with anti-Ro/SSA reactivity, 20 sera from patients with systemic diseases without anti-Ro/SSA immune reactivity, as well as against 65 sera from normal individuals. A large proportion of the tested sera reacted against all three peptide analogues, although with a preference for the unmodified form of the epitope. In conclusion, post-translational modifications of the major Ro60 kDa B cell epitope can alter the autoantibody binding.
Determination of Total Flavones in Desmodium Sambuse

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Objective:To establish ultraviolet spectrophotometry for the determination of total flavones in Desmodium Sambuse.Method: Quercetin was used as reference material,and the samples were determined at 510 nm.Result: The linear range for quercetin was 0.020 8-0.104 0 g·L-1.(r=0.999 7),The recovery rate was 98.09%;RSD 1.34%(n=5).Conclusion: This method was easy to handle with accuracy and reproducibility and suitable for quantitative determination of flavonoid in Desmodium Sambuse.
[Advancement of E2F1 in Common Tumors].

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The cell cycle-related transcription factor E2F1 is a member of the cell cycle-related transcription factor E2F family, mainly involved in various cell processes including cell cycle progression, DNA repair, DNA replication, cell differentiation, proliferation, and apoptosis. E2F1 is highly expressed in a variety of tumor tissues and cells, and it plays a role as a cancer-promoting gene. The up-regulation of E2F1 expression is closely related to the occurrence, development, metastasis and prognosis of tumors. Therefore, E2F1 is expected to become a new target for cancer treatment. This article reviews the latest research progress of E2F1 in current common tumors. .
Dualizing rings and a characterization of finite representation type

Field: Mathematics (Physical Sciences)

Using the relation between indecomposable endofinite right and left Lambda-modules, we introduce (right) dualizing rings and show that a ring Lambda is of finite representation type if and only if Lambda is right dualizing and every right Lambda-module is a direct sum of (finitely presented) indecomposable Lambda-modules. We present also criteria for the existence of non-finitely presented indecomposable endofinite modules over a dualizing ring.
Heat shock protein may be an immune target in the host's antitumor resistance.

Field: Immunology and Microbiology (Life Sciences)

We identified transfomation-associated cell surface antigens (TAAs) that are expressed on a W31 H-rasoncogene trasformant of WFB rat fibroblast. One of TAAs, defined by mAb067, showed the enhanced expression by physicochemical stressors, and was supposed to be 70 heat shock cognate protein (hsc) itself. It was also shown that this antigen may be a target for CD4-CD8- double negative T cell (DNT), since mAb067 completely blocks the cytotoxicity of DNT against W31.These data strongly suggest that 70 hsc is a tumor antigen, and is a potential target for the host's tumor immunity. The capability of antigenic peptide presentation of 70 hsc was discussed.
Development of Teacher Performance in Educational Measurements and Evaluation through Self-monitoring Strategies

Field: Social Sciences (Social Sciences)

This research was to develop teacher performance in educational measurements and evaluations through self-monitoring strategies. Participants comprised 10 administrators and teachers. Qualitative data was collected from informal interviews and a focus group. The research was conducted in five steps for improving self-monitoring. The results of this research found that the self-monitoring strategies showed that teachers learnt best from the concrete example in the report on test preparation for the Basic Education National test. Teachers intended to learn about learning educational measurements and evaluations through participation in activities. By applying the self-monitoring process, teachers gained further knowledge in learning measurements and evaluations, participating in action planning, as well as greater realization and awareness of the importance of learning measurements and evaluations.
Knockdown of FANCL may impair multi-lineage progenitor expansion from cord blood stem cells

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Fanconi anemia (FA) is a rare, inherited chromosomal instability disorder characterized by bone marrow failure and susceptibility to cancer. Cells from patients with FA accumulate excessive chromosome breaks when exposed to DNA damaging agents; therefore, providing evidence that the FA pathway functionally exists as an integral part of DNA repair. Recent evidence suggests that alternative functions of the FA pathway exist, yet precisely for what cell type and context is unknown. Our laboratory has evidence that the FA pathway may regulate the signaling output of Wnt/β-catenin, a known signal transduction pathway that regulates a hematopoietic stem cell’s ability to expand and self-replicate. Specifically, FANCL may enhance the signaling output of β-catenin. Given the relationship between FANCL and this pathway, as well as the observation that hematopoietic stem cells from FA patients are remarkably susceptible to apoptosis and display defective stem cell properties, we investigated whether introducing the FA phenotype in cord blood stem cells impacts their self-renewal properties in colony forming cell assays. We tested a set of small hairpin RNA constructs for their ability to knockdown FANCL by western blot and qRT-PCR analysis. Our preliminary data shows that FANCL-deficient hematopoietic stem cells have reduced capacity to form multi-lineage progenitors. Based on this preliminary work, we will further investigate if perturbation of the Wnt/β-catenin pathway is the mechanistic explanation for why these cells have impaired multi-lineage potential. Identifying these mechanisms may provide insights into how Wnt/β-catenin signaling may be modulated by other pathways to maintain the hematopoietic stem cell pool. Thus, inherited or acquired perturbations of this regulation may lead to bone marrow failure.
Multianode Microchannel Array Detector Systems: Performance Characteristics

Field: Physics and Astronomy (Physical Sciences)

Multianode microchannel array detector systems with formats as large as 256 x 1024 pixels are currently under evaluation in the laboratory. Performance data recorded with sealed ultraviolet and visible-light detector tubes have shown that the detector systems have unique characteristics that make them complementary to photoconductive ar-ray detectors, such as charge-coupled devices, and superior to alter-native pulse-counting detector systems employing high-gain microchannel plates.
The Status of Puritan-Indian Scholarship

Field: Arts and Humanities (Social Sciences)

ing, perhaps, is the number of skillful analyses of PuritanIndian affairs-a challenging subject long shrouded in myths and misrepresentations. As ethnocentric as it sometimes is, Alden Vaughan's New England Frontier raised nearly all of the important questions about Puritan and native behavior toward each other and set off a spate of critical rejoinders from Francis Jennings, Neal Salisbury, and G. E. Thomas.' The replies to Vaughan, along with the scholarship of Gary Nash, James Axtell,2 and James Ronda have increased considerably our methodological sensitivity toward Native American cultures in New England and corrected the long-held belief that the Puritan missionary movement to the Indians was widespread and successful in its goals. Yet the revisionist historians, in attempting to counter Vaughan's condescension toward the static nature of Indian life and his overemphasis on the missionary movement, tend to ignore the extent of religious motivation behind Puritan treatment of Indians. They deempha-
Factors Affecting Survival of Channel Catfish after Surgical Removal of Testes

Field: Veterinary (Health Sciences)

Abstract Testes from adult male channel catfish (Ictalurus punctatus; N= 73) and blue catfish (I. furcatus; N= 16) were surgically removed, and the incisions closed. Variables evaluated for their effect on survival of fish were method of anesthesia (tricaine [MS–222] at 12 and at 23°C, and metomidate at 23°C), suturing procedure (suture, adhesive, and adhesive plus suture), and treatment with antibiotic (erythromycin) or without antibiotic. Postsurgery survival was determined 8–10 weeks later. Observed survival was 61 and 53% among fish treated with MS-222 at 12 and 23°C, respectively. The lower temperature decreased bleeding and increased the efficacy of MS-222. Metomidate-treated fish had significantly higher (P < 0.05) survival (74%) than MS-222-treated fish. Fewer of the metomidate-treated fish had incisions reopen because their swimming behavior in the recovery tank was more normal than that of MS-222-treated fish. Closure of incisions with adhesive alone resulted in 100% mortality. No difference (P > 0.05) in survival was observed between fish in the suture (68%) and suture plus adhesive (58%) treatments. Survival was significantly higher (P < 0.05) for blue catfish (94%) than for channel catfish (61 %). No differences in survival were observed between small (≤2.0-kg; 59%) and large (> 2.0-kg; 67%) fish, nor between antibiotic-treated (66%) and untreated (68%) fish. Survival among fish treated during the peak spawning period (75%) was higher (P < 0.05) than that of those treated during the late spawning period (21%).