jimnoneill/paper-to-field-training huggingface dataset:
Towards Building Intrusion Detection Systems for Multivariate Time-Series Data

Field: Computer Science (Physical Sciences)

Abstract Recent network intrusion detection systems have employed machine learning and deep learning algorithms to defend against dynamically evolving network attacks. While most previous studies have focused on detecting attacks which can be determined based on a single time instant, few studies have paid attention to subsequence outliers, which require inspecting consecutive points in time for detection. To address this issue, this paper applies a time-series anomaly detection method in an unsupervised learning manner. To this end, we converted the UNSW-NB15 dataset into the time-series data. We carried out a preliminary evaluation to test the performance of the anomaly detection on the created time-series network dataset as well as on a time-series dataset obtained from sensors. We analyze and discuss the results.
Public support for affirmative action policies favouring women and migrants in recruitment processes: An international survey experiment

Field: Social Sciences (Social Sciences)

Affirmative action policies (AAP) polarise the public debate in Western democracies as they involve favouring one candidate at the cost of others because of their group membership. Against this backdrop, we ran a factorial survey experiment in Denmark, France and Germany on the introduction of a hypothetical regulation favouring women and immigrants with equal qualifications in the recruitment process for a management position (N = 4264; YouGov online panel). Our data show that support for AAP for women is significantly greater than for immigrants in all three countries. Moreover, support for AAP is much higher in France than in Germany and Denmark. Germans and Danes show similar low support for AAP for immigrants, while support for AAP for women is higher in Germany than Denmark. We conducted multilevel regression models to investigate the power of several attitudinal factors in explaining target group and country differences. Results show that respondents’ varying levels of ethnic and gender prejudice and perceived disadvantage entirely explain target group differences in support for AAP. Furthermore, differences between Germany and Denmark in the support of AAP for women are explained by different levels of prejudices and perceived disadvantage, and attitudes towards state intervention. However, these attitudinal variables cannot explain why support for AAP is much higher in France.
The Impact of Volunteering on Seniors’ Health and Quality of Life: An Assessment of the Retired and Senior Volunteer Program

Field: Health Professions (Health Sciences)

Past research suggests that senior citizens often face challenges related to deteriorating physical and mental health, and the quality of their lives may suffer as a result. Past research also suggests that volunteering can improve the health and quality of life for seniors. In the present study, 451 volunteers enrolled in the Retired and Senior Volunteer Program (RSVP) completed surveys including questions regarding their volunteer experiences and how these experiences have affected their health and quality of life. The results suggest that volunteering through RSVP is associated with improvements in health and quality of life across a variety of dimensions. Furthermore, these improvements may be particularly greater for women, current volunteers, and older seniors. These findings may help guide interventions designed to enhance the health and well-being of senior citizens in a variety of settings.
The Life of Elementary School Subjects on the Q&A Method in Indonesia

Field: Social Sciences (Social Sciences)

This research is motivated by the results of observations in the form of interviews with an elementary school in the city of Palangka Raya, Central Kalimantan. The type of research used in this research is qualitative research, the subjects of this research are teachers who in fact dominate the question and answer method system. It is known that most students are very enthusiastic and enjoy the question and answer method learning system, thus helping to support efficiency and effectiveness during the learning activities carried out. In addition, the question-and-answer-based method helps teachers evaluate the level of students' understanding and knowledge of the material explained by the teacher, as well as providing opportunities to attract students' attention and efforts to get direct feedback from students who are involved in the learning process. The question and answer method implied by the teacher in teaching is very closely related to student learning outcomes, because the material delivered by the teacher using the question and answer method affects the cognitive, affective, and psychomotor domains. In this case it can also add religious values ​​to shape the character of students' spiritual knowledge. In this case it can not only shape students' knowledge and spiritual character but also can foster a sense of empathy and sympathy for students towards the people around them.
Comprehensive review of metal-based coordination compounds in cancer therapy: from design to biochemical reactivity

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Abstract Throughout history, metal-based coordination compounds have been used for medical purposes, including the treatment of various illnesses like cancer. Since the discovery of cisplatin in 1965, many other metal coordinating complexes have been developed and evaluated, involving metals such as platinum, iron, zinc, ruthenium, gold, silver, titanium, and copper. The goal behind these efforts is to create effective and safe medications. At the moment, there are a lot of studies talking about the use of cytostatic metal complexes, mainly on promising platinum- and non-platinum-based drugs in both preclinical and clinical trials. However, there is a lack of recent comprehensive studies that cover both the chemical and biological aspects of metal-based coordinating molecules in the context of cancer therapy. This review aims to provide a thorough analysis of the coordination chemistry of existing and innovative cytostatic substances. It will include a description of their design and synthesis, as well as a summary of the biochemical reactivity and physicochemical features of potential metal-containing complexes.
ANALISIS VIDEO CLIP TONGTOLANG SAMBASUNDA DALAM PERSPEKTIF SEMIOTIKA ROLAND BARTHES

Field: Arts and Humanities (Social Sciences)

ABSTRACT This study analyzes the audio-visual video clip of Tongtolang Sambasunda. The purpose of this study is to reveal the symbols in the Tongtolang Sambasunda video clip. Video clip is one of the symbolic communication media that functions as a conveyer of information to the public. This study uses Roland Barthes' symbolic approach, namely the "subject" of art experience, which remains and persists, is not the subjectivity of the person experiencing it, but the work itself. From the research results it is known that understanding (subtility intelligence), explication (subtility expicandi), and application (subtility applicandi) of the Tongtolang Sambasunda audio-visual video clip are paradoxical expressions of the lyrics of the Tongtolang song. That when the father character falls into the world of polygamy, he is actually rising because he managed to get the young girl he wanted. Man falls to the top, that is, opposes or denies the truth that he has so far adhered to, and he begins to struggle to find that "way up". When he falls, he is actually rising, Paradox. ABSTRAK Penelitian ini menganalisis audio visual video clip Tongtolang Sambasunda. Tujuan penelitian ini untuk mengungkap simbol dalam video clip Tongtolang Sambasunda. Video Clip merupakan salah satu media komunikasi simbolik yang berfungsi sebagai penyampai informasi terhadap publik. Penelitian ini menggunakan pendekatan simbolik Roland Barthes yaitu "Subjek" pengalaman seni, yang tetap dan bertahan, bukanlah subjektivitas orang yang mengalaminya, melainkan karya itu sendiri. Dari hasil penelitian diketahui bahwa pemahan (subtilitas intellegendi), eksplikasi (subtilitas expicandi), dan aplikasi (subtilitas applicandi) dari audio visual video clip Tongtolang Sambasunda merupakan ungkapan paradoks dari syair lagu Tongtolang. Bahwa ketika tokoh Bapa jatuh ke dalam dunia poligami sesungguhnya ia sedang naik ke atas karena berhasil mendapatkan gadis muda yang diinginkan. Manusia jatuh ke atas, yakni menentang atau menyangkal kebenaran yang selama ini dianutnya, dan mulailah ia berjuang untuk menemukan “jalan ke atas” itu. Ketika ia jatuh, sebenarnya ia sedang naik, Paradoks.
A COMPARATIVE STUDY: PERFORMANCE OF LARGE LANGUAGE MODELS IN SIMPLIFYING TURKISH COMPUTED TOMOGRAPHY REPORTS

Field: Health Professions (Health Sciences)

Objective: This study evaluated the effectiveness of various large language models (LLMs) in simplifying Turkish Computed Tomograpghy (CT) reports, a common imaging modality.Material and Method: Using fictional CT findings, we followed the Standards for Reporting of Diagnostic Accuracy Studies (STARD) and the Declaration of Helsinki. Fifty fictional Turkish CT findings were generated. Four LLMs (ChatGPT 4, ChatGPT-3.5, Gemini 1.5 Pro, and Claude 3 Opus) simplified reports using the prompt: "Please explain them in a way that someone without a medical background can understand in Turkish.” Evaluations were based on the Ateşman’s Readability Index and Likert scale for accuracy and readability.Results: Claude 3 Opus scored the highest in readability (58.9), followed by ChatGPT-3.5 (54.5), Gemini 1.5 Pro (53.7), and ChatGPT 4 (45.1). Likert scores for Claude 3 Opus (mean: 4.7) and ChatGPT 4 (mean: 4.5) showed no significant differ ence (p>0.05). ChatGPT 4 had the highest word count (96.98) compared to Claude 3 Opus (90.6), Gemini 1.5 Pro (74.4), and ChatGPT-3.5 (38.7) (p<0.001).Conclusion: This study shows that LLMs can simplify Turkish CT reports at a level that individuals without medical knowledge can understand and with high readability and accuracy. ChatGPT 4 and Claude 3 Opus produced the most comprehensible sim plifications. Claude 3 Opus’ simpler sentences may make it the optimal choice for simplifying Turkish CT reports.
CsNAC17 enhances resistance to Colletotrichum gloeosporioides by interacting with CsbHLH62 in Camellia sinensis

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract The pathogen Colletotrichum gloeosporioides causes anthracnose, a serious threat to tea trees around the world, particularly in warm and humid regions. RNA-Seq data have previously indicated NAC transcription factors are involved in anthracnose resistance, but underlying mechanisms remain unclear. The BiFC, Split-LUC, and Co-IP assays validated the interaction between CsbHLH62 and CsNAC17 identified through yeast two-hybrid (Y2H) screening. CsNAC17 or CsbHLH62 overexpression enhanced anthracnose resistance, as well as enhanced levels of H2O2, hypersensitivity, and cell death in Nicotiana benthamiana. The NBS-LRR gene CsRPM1 is regulated by CsNAC17 by binding directly to its promoter (i.e. CACG, CATGTG), while CsbHLH62 facilitates CsNAC17’s binding and increases transcriptional activity of CsRPM1. Additionally, transient silencing of CsNAC17 and CsbHLH62 in tea plant leaves using the virus-induced gene silencing (VIGS) system resulted in decreased resistance to anthracnose. Conversely, transient overexpression of CsNAC17 and CsbHLH62 in tea leaves significantly enhanced the resistance against anthracnose. Based on these results, it appears that CsbHLH62 facilitates the activity of CsNAC17 on CsRPM1, contributing to increased anthracnose resistance.
Long-Term Expression and Safety of Administration of AAVrh.10hCLN2 to the Brain of Rats and Nonhuman Primates for the Treatment of Late Infantile Neuronal Ceroid Lipofuscinosis

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Late infantile neuronal ceroid lipofuscinosis (LINCL), a fatal, lysosomal storage disorder caused by mutations in the CLN2 gene, results in a deficiency of tripeptidyl-peptidase I (TPP-I) activity in neurons. Our prior studies showed that delivery of the human CLN2 cDNA directly to the CNS, using an adeno-associated virus serotype 2 (AAV2) vector, is safe in children with LINCL. As a second-generation strategy, we have demonstrated that AAVrh.10hCLN2, a rhesus-derived AAV vector, mediates wide distribution of TPP-I through the CNS in a murine model. This study tests the hypothesis that direct administration of AAVrh.10hCLN2 to the CNS of rats and nonhuman primates at doses scalable to humans has an acceptable safety profile and mediates significant CLN2 expression in the CNS. A dose of 10(11) genome copies (GC) was administered bilaterally to the striatum of Sprague Dawley rats with sacrifice at 7 and 90 days with no significant impact except for mild vector-related histopathological changes at the site of vector administration. A dose of 1.8×10(12) GC of AAVrh.10hCLN2 was administered to the CNS of 8 African green monkeys. The vector-treated monkeys did not differ from controls in any safety parameter except for mild to moderate white matter edema and inflammation localized to the administration sites of the vector. There were no clinical sequelae to these localized findings. TPP-I activity was >2 SD over background in 31.7±8.1% of brain at 90 days. These findings establish the dose and safety profile for human clinical studies for the treatment of LINCL with AAVrh.10hCLN2.
Risk of Developing Sudden Sensorineural Hearing Loss in Patients with Acute Otitis Media: A Multicenter Retrospective Analysis

Field: Medicine (Health Sciences)

Objective: The aim of the study was to determine the etiology of Sudden Sensorineural Hearing Loss (SSHL) and to call attention to Acute Otitis Media (AOM) with SSHL. Study Design and Setting: We conducted a retrospective, multicenter analysis of SSHL. We were used spearman correlation matrix test for correlations between all variables. One hundred twelve patients with SSHL were evaluated. Results: A total of 112 patients (62 males, 50 females) ranging in age from 17 to 70 years (average male 40.21 ± 14.04, average female 40.26 ± 11.16) were included. Fourteen of these had AOM. The majority of patients had moderate hearing loss. Flat and down-sloping types of audiogram were also observed (P<0.05). There was a positive relationship between SSHL and AOM, SOM, cardiac pathology as hypertension. No significance was established in terms of age or sex (p>0.05). Otoscopic examination was consistent with AOM. SSHL occurred as mixed-type hearing loss. Tympanometry was observed as type A. Conclusion: In the treatment and follow-up periods, AOM patients should be checked and treated for the presence (if any) of early hearing loss.
Monetary Policy and Capital Market Performance: An Empirical Evidence from Nigerian Data

Field: Economics, Econometrics and Finance (Social Sciences)

This study utilized time series data to determine the effect of monetary policy on the performance of Nigerian capital market. The study was motivated by the inconclusive debate on the real effect of monetary policy on capital market performance. Specifically, this study ascertained the effect of monetary policy rate and cash reserve ratio on the performance of Nigerian capital market surrogated by all share index. Secondary data for the period 1986 to 2016 were collected from the Nigerian Stock Exchange and Central Bank of Nigeria annual reports of various editions. The study applied the Ordinary Least Square (OLS) regression technique and causality analysis in which variations in all share index was regressed on monetary policy rate and cash reserve ratio. The analysis revealed that monetary policy tools have no significant effect on capital market performance. The monetary policy rate has negative significant relationship with capital market performance while cash reserve ratio positively relates with performance of the capital market. Considering the findings emanating from this study, the Central Bank of Nigeria should reduce the current double digit monetary policy to a single digit to attract investments in the capital market. Cash reserve ratio which is currently at 22.5% be lowered to the range: 10%-12% to cause an upsurge in money supply which will in turn improve capital market performance through upward movement in all share indexes.
Design of soil moisture control prototypes for plant cultivation

Field: Engineering (Physical Sciences)

Soil moisture is one of the important parameters for the process of hydrology, biology and biogeochemistry. In the cultivation of plants, it is necessary to control soil moisture to get good crop yields. In this study we designed a system of automatic soil moisture control for the purposes of crop cultivation. The system works by watering automatically when the soil moisture for the plant decreases. The system is designed using an STM32 microcontroller and humidity sensor to check soil moisture. STM 32 microcontroller will process the information that is delivered by sensor by giving a limitation range on a certain value between <; 3000 and >3000. If the sensor reads is <; 3000 then STM 32 sends the signal to the servomotor which then servomotor will move to 0° position and if the result is >3000 then STM 32 will send a signal to the servomotor to move to 180 ° position. From the test results it is proven that the system can work well automatically with a success rate of around 90%.
“French element” in the Russian art culture of the mid XVIII century

Field: Arts and Humanities (Social Sciences)

The subject of this research is the reflection of Russian realities of the mid XVIII century in cultural sphere. The article touches upon the problem of cross-cultural communication between Russia and France in the XVIII century: the theme of &ldquo;French presence&rdquo; in the Russian art and theater culture of the first half and the middle of the XVIII century. The acquired results elucidate the characteristic features of the relations between French and Russian people during this period. The research was conducted with consideration of the unity of internal and external, subjective and objective factors within the framework of the cultural-historical process. The conclusions were made leaning on the analysis of the entire range of sources use and existing research traditions. The article reveals the contribution of the French representatives of art and culture while their stay in Russia, as well as describes the forms and manifestations of their activity that in prospect affected the image of Russia. The author believes that working at the Russian Court, the French representatives imposed the vision of their country on Russia, transforming the Russian images in the French spirit. The presented materials are valuable for the study of cross-cultural communication between Russia and France in the XVIII century. This article is important and relevant in the conditions of constantly developing cultural dialogue and determination of the new vectors of cooperation between the countries.
‘It's a bit like flying’: developing participatory theatre with the under-twos: a case study of Oily Cart

Field: Arts and Humanities (Social Sciences)

Abstract This article describes a case study of a new venture by the children's theatre company Oily Cart to develop a participatory theatre piece for carers and their under-two-year-olds, entitled Clouds. Given what little is known about how to design and conduct arts events with this age phase, a case study offered the opportunity to identify features and factors which might then pertain to other, similar ventures. At a time of rapid expansion in arts opportunities for the very young, it is important to move beyond the usual evaluation procedures to research such arts occasions in more depth. The study adopted the usual case study design of collecting data from many, varied sources including documentation, observations of performances, interviews and direct participation. Although orientated by some initial guiding questions, the study remained open to foci as they emerged. In particular the reseacher became interested in the nature of the experience for the very young children and their carers. This, in turn, threw attention onto those factors which facilitated the participation of very young children—the design of the theatre piece and, importantly, the facilitative skills of the actors in improvising the playful sequence of episodes. One of the conclusions to emerge is that theatre for very young children requires specific and additional sets of skills from writer, designer and composer and from the participating actors, which, with Oily Cart, have evolved from considerable experience. The specific skills of the improvising ‘inter-actors’ with the child–adult dyads emerged as crucial and central. The study also drew attention to the demands on adult carers to become participatory players. While finding that the majority of carers adapted to the experience willingly, easily and enjoyably, some found the participatory role less comfortable. Some possible reasons for this are explored.
Decreased specific force and power production of muscle fibers from myostatin-deficient mice are associated with a suppression of protein degradation

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Myostatin ( MSTN) is a member of the transforming growth factor-β superfamily of cytokines and is a negative regulator of skeletal muscle mass. Compared with MSTN +/+ mice, the extensor digitorum longus muscles of MSTN −/− mice exhibit hypertrophy, hyperplasia, and greater maximum isometric force production (F o ), but decreased specific maximum isometric force (sF o ; F o normalized by muscle cross-sectional area). The reason for the reduction in sF o was not known. Studies in myotubes indicate that inhibiting myostatin may increase muscle mass by decreasing the expression of the E3 ubiquitin ligase atrogin-1, which could impact the force-generating capacity and size of muscle fibers. To gain a greater understanding of the influence of myostatin on muscle contractility, we determined the impact of myostatin deficiency on the contractility of permeabilized muscle fibers and on the levels of atrogin-1 and ubiquitinated myosin heavy chain in whole muscle. We hypothesized that single fibers from MSTN −/− mice have a greater F o , but no difference in sF o , and a decrease in atrogin-1 and ubiquitin-tagged myosin heavy chain levels. The results indicated that fibers from MSTN −/− mice have a greater cross-sectional area, but do not have a greater F o and have a sF o that is significantly lower than fibers from MSTN +/+ mice. The extensor digitorum longus muscles from MSTN −/− mice also have reduced levels of atrogin-1 and ubiquitinated myosin heavy chain. These findings suggest that myostatin inhibition in otherwise healthy muscle increases the size of muscle fibers and decreases atrogin-1 levels, but does not increase the force production of individual muscle fibers.