jimnoneill/paper-to-field-training huggingface dataset:
Konstrukce identity dlouhodobě zaměstnaných Romů v Litvínově

Field: Social Sciences (Social Sciences)

In the thesis the author is focused on identity construction of long-term employed Roma in Litvínov city. She proceeds from an assumption, supported by several research, that Roma are vastly stigmatized in Litvínov city. One of the most widespread stigmas is probably persuasion of not working Roma. Long-term employed Roma are defying this prejudice to some extent. In spite of this, because of their visible ethnical apperance they are still put into stigmatized ethnic group. In the theoretical part of the thesis, the author concentrates on introducing theoretical concepts of identity construction to the reader. She also familiarize the reader with Roma minority living in Czech Republic. In the practical part, she introduces her own research, based on six half- structured interviews with long-term employed Roma living in Litvínov. Based on collected data she comes to conclusion and answers her research questions.
Ivosidenib in Chinese patients with relapsed or refractory isocitrate dehydrogenase 1 mutated acute myeloid leukemia: a registry study

Field: Medicine (Health Sciences)

Ivosidenib, an isocitrate dehydrogenase 1 ( IDH1 ) inhibitor, has demonstrated clinical benefits in a pivotal study (AG120-C-001) in patients with IDH1 -mutated (m IDH1 ) acute myeloid leukemia (AML). A registry study (CS3010-101: NCT04176393) was conducted to assess the pharmacokinetic (PK) characteristics, safety, and efficacy of ivosidenib in Chinese patients with relapsed or refractory (R/R) m IDH1 AML. Patients received ivosidenib 500 mg once daily for 28-day cycles until disease progression. Ten subjects underwent intensive PK/progressive disease (PD) assessments. All subjects had the clinical response assessed at screening, every 28 days through month 12, and then every 56 days. Between November 12, 2019, and April 2, 2021, 30 patients were enrolled; 26 (86.7%) had de novo AML and 18 (60.0%) were transfusion-dependent at baseline. Following single and repeated doses of ivosidenib, median time to maximum plasma concentration ( T max ) was 4.0 and 2.0 hours, respectively. The inter-individual variability of pharmacokinetic exposure was moderate to high (coefficient of variation [CV], 25%–53%). No obvious accumulation was observed after repeated doses at cycle 2 day 1. Regarding the clinical response, the CR + CRh rate was 36.7% (95% confidence interval [CI]: 19.9%–56.1%), the median duration of CR + CRh was 19.7 months (95% CI: 2.9 months–not reached [NR]), and median duration of response (DoR) was 14.3 months (95% CI: 6.4 months–NR). Consistent clinical benefits and safety of ivosidenib were consistently observed at the final data cutoff with median follow-up time 26.0 months, as compared with primary data cutoff, and the data from Chinese R/R m IDH1 AML patients were also consistent with results from pivotal study.
Activated Signaling Pathways and Apoptotic Mechanisms in Resveratrol Applied Chronic Myeloid Leukemia Cells and the Involvement of Ceramide Metabolizing Genes on These Mechanisms

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Resveratrol, an important phytoalexin in many plants, has cytotoxic effects on several cancer cells. Ceramide is a significant sphingolipid which affects many signaling pathways regulating cell senescence, migration, and cell cycle arrest. Intracellular ceramide level is balanced by glucosylceramide synthase (GCS), the converter of ceramide to glucosylceramide, and sphingosine kinase-1 (SK-1) that convert ceramide to sphingosine 1-phosphate (S1P). Ceramide functions as an apoptotic molecule whereas glucosylceramide S1P function as anti-apoptotic. An important cell-permeable analogue of natural ceramides, C8:ceramide, increases intracellular ceramide levels significantly, while 1-phenyl-2-decanoylamino-3-morpholino-1-propanol (PDMP) and SK-1 inhibitor increase accumulation of ceramides by inhibiting GCS and SK-1, respectively. Chronic myelogenous leukemia (CML), a hematological disorder, results from the generation of BCR/ABL oncogene. In this study, we examined the roles of ceramide metabolizing genes in resveratrol-induced apoptosis, and the expression profiles of 84 genes underlying apoptosis, cell cycle control, DNA damage repair, and invasion and metastasis in human K562 CML cells treated with resveratrol. There were synergistic cytotoxic and apoptotic effects of resveratrol with coadministration of C8:ceramide, PDMP and SK-1 inhibitor. We observed significant increases in expression levels of LASS genes, and decreases in expression levels of GCS and SK-1 in K562 cells in response to increasing concentrations of resveratrol. There were also significant increases in the expression levels of SERPINB5, FAS, TNFRSF, MTSS that are related with tumor suppression, and decreases in Myc expression. Our data, in total, showed for the first time that resveratrol might kill CML cells through increasing intracellular generation and accumulation of apoptotic ceramides.
Adaptive Control of Nuclear Reactors Using a Digital Computer

Field: Engineering (Physical Sciences)

An adaptive system for the control of the power level of a nuclear reactor is described. The controller has a square-law element of variable gain, optimum values for which have been obtained from off-line computations for certain power levels and parameter values. When conditions in the reactor deviate from those assumed for the off-line optimization, the gain factor is adapted on-line, such that the difference between actual and demanded power levels is minimized. An existing power reactor and associated control system have been simulated, as well as the proposed adaptive scheme. The results show that the adaptive controller gives improvements by at least an order of magnitude in the accuracy of following power demand changes, and at the same time reduces the necessary control effort. Since the scheme entails only a small number of arithmetic and logical operations and has limited memory requirements, it may be implemented on a conventional process computer, or built as a special purpose digital control system.
Predicting Election Results through Non-Response Substitution in Polls

Field: Computer Science (Physical Sciences)

In the results of the election polls, the candidates' approval ratings are not only a major concern of the people, but also an important factor in establishing the election strategy of the party concerned. However, if there is an inaccurate or distorted result of the election poll, it can cause a big problem because of its influence, and the controversy about the poll often arises. There are many cases in which the actual election results are different from the results of the polls, and political parties and research institutes, which are related to the polls, are making efforts to improve the accuracy of the election forecasts. The purpose of this study is to improve the accuracy of election prediction by replacing non-response through machine learning algorithm using the survey data of the 20th Presidential Election, the 2021 Busan Mayor By-election, and the 8th National Simultaneous Local Election (Busan Metropolitan City, Nam-gu, Gimhae Mayor). For this purpose, first, the data excluding the non-response (I do not know/don't know) was separated into train data and the data selected as non-response (I do not know/don't know) was separated into test data. Second, Random Forest, XGBoost, and LightGBM methods were applied, and only the top three questions were used by deriving the importance of questions when predicting candidates through train data. Third, through the model learned based on the train data, the non-response of the test data was replaced with the response of one candidate, and the corresponding data and the train data were combined to calculate the percentage of votes for each candidate. As a result of comparing the actual election results with the percentage of votes for each candidate by replacing the non-response, it was confirmed that the Random Forest method is suitable for the model for improving the accuracy of election prediction through non-response substitution.
Hybrid biogas plant producing electricity

Field: Energy (Physical Sciences)

Energy is thc major cause behind the development of a nation. By thinking on it we have worked onthe biogas plant and modified it to generate electricity. This generated electric current is sufficientenough to power an entire house. Also our idea can be implemented in country with huge amount oforganic waste material.Have you any time thought of "Just a switch in your house which when in ON condition can fetch youelectricity, and in OFF condition can generate biogas". Yes this is absolutely possible and our extremehard efforts have made us to achieve this successfully.Our project is based on four absolutely different and innovative steps.1. Removal of electrons from bacterial cells by use of accurate potential difference electrodes.(asin the microbial fuel cell).2. Rectify this current by use of a special device designed by LIS and get the output as 0.25Y.3. This obtained voltage is again appl ied to the microbial culture in biogas plant. By this accumulationof acetic acid takes place in the biogas fermenter.4. The accumulated acid can be easily converted into H2 gas by the action of microbes fromenvironment, using acetic acid as a selective component.5. Further on passing this gas through hydrogen cells large amount of electricity can be generatedas per our requirement.The entire process takes place in biogas plant fermenter and hydrogen gas can be generated onlywhen the 0.25V voltage is applied to the culture in the plant's frementer. In the absence of voltagethis plant produces 95 % methane and not 70% as per the primitive plant did (a solid experimentalproof for this). Thus pure methane as well as electricity can be generated by this plant by the switchover of a single switch. For implementation of this technique large funds are also not required andeven a simple farmer can adopt this technique. Moreover the existing biogas plants in the country canalso be modified by the introduction of certain metal electrodes in it. It can be concluded that thistechnique to certain extent can help in the development of rural areas in developing countries andmake their dream of "developed nation" achived.
[Continuous ambulatory peritoneal dialysis: efficient treatment for children with terminal uremia].

Field: Medicine (Health Sciences)

We have reviewed records of 12 children underwent CAPD between January 84 and May 88, ranging in age from 7 month to 16 years (mean age 8.9 +/- 4.9 years). CAPD treatment lasted from 3 to 24 months (average 10.3 months). Exchanges of dialysis fluid were performed by parents (8 cases) or children (3); mean volume was 41.7 +/- 8.7 ml/kg/exchange (range 32-58 ml/kg). During 132 patient months of treatment laboratory data showed a good metabolic control expect a tendency to hypoalbuminemia. There were 3 catheter changes. Complications were: peritonitis (15 episodes or one infection every 8.8 patient/treatment/months), hypertension (5 cases), hypervolemia (2), cuff extrusion (4), local exit site (5) and tunnel (2) infections and hernias (2). CAPD has been continued in 3 children; 6 other received renal transplantation, one was switched to hemodialysis and 2 died. This study has demonstrated that CAPD was an effective treatment for renal failure in children waiting renal transplant. Cuff extrusion and hypoalbuminemia were common complications in our children.
Determined the critical factors of facial mask products and size design

Field: Business, Management and Accounting (Social Sciences)

Facial mask has been essential products for skin care in Taiwan. There is more than 50 billion market for cosmetic facial mask. The purpose of this study was to determine the critical design factors of cosmetic facial mask by factors analysis and analytic hierarchy process. Further, the sizes of face and facial mask have been compared in 9 characteristics. For factors analysis, the five dimensions that involved the product characteristics, usability, marketing and brand spokesman, purchased convenience and price, shape of facial mask. In overall sorting by AHP, the comfortable, perfectly fit, price, shape of facial mask, function, ingredient are the most priorities of design factors criteria. Sizes of facial mask have been re-designed to fitting the facial anthropometry.
Credit Constraints and Fiscal Policy in a Model of Growth with Endogenous Fertility

Field: Economics, Econometrics and Finance (Social Sciences)

This paper investigates economic growth under liquidity constraints by taking into account the choices of fertility, human capital and savings. In a model of four overlapping generations, parents are altruistic towards their children and finance their education investment. The government provides education subsidies to young adult parents and levies taxes on income of the adult generation. Sensitivity analysis on borrowing limits and tax parameters highlights conflicting effects on the main endogenous variables at steady state. Lower liquidity constraints decrease savings and capital accumulation. From model simulation, we derive an inverted U-shaped curve relating the borrowing limits to fertility, education and growth, meaning that financial reforms in the less developed countries have positive effects on the economy in the long-run, even if they raise fertility and reduce savings. Greater government subsidies to human capital investments and lower income taxes have positive effects on savings and fertility. Numerical simulations show that: human capital investment has an inverted Ushaped relation with income taxes and education subsidies; economic growth decreases with greater income taxes and increases with higher education subsidies.
Discourse Ambiguity in a Contract Fraud Case: US v. David Smith

Field: Arts and Humanities (Social Sciences)

Abstract Government contracts can be very complex, as illustrated by this 1997 case involving a Texas-based manufacturer of helicopters. It was made even more complicated by the fact that the company was a subsidiary of a French corporation that could legitimately make sales to other countries without the Texas company’s involvement or knowledge. The contract in question was eligible for the US Foreign Military Financing Program (FMF), created to promote the interests of domestic American businesses by providing funds to eligible allies to support their costs. Smith, president of the US company, was the target of a federal investigation concerning his knowledge of possible misuse of FMF funding. Over a two-year period, one of Smith’s employees secretly tape-recorded conversations with Smith that the government believed showed his complicity in contract fraud. Linguistic analysis of the ambiguity of the words and expressions used in these conversations, among other things, showed that Smith was not guilty.
Typology of fasade building in kayu tangan street corridor, Malang City

Field: Arts and Humanities (Social Sciences)

The Kayu Tangan Street Corridor is one of the areas that play an important role for Malang City. Building facade in this road corridor has significance in creating the visual character of Malang. The facade is an important architectural element of buildings because it can show the function and the significant meaning of the building. This study aims to determine how to classify the type of facade of the existing building in Street Corridor of Kayu Tangan that will affect the visual quality of this area. This study used a qualitative approach and descriptive-explorative methods. Selection of the sample was done by purposive sampling methods based on the buildings function. This study expected to gain a typology of building facade at Street Corridor of Kayu Tangan and led the development goal on the area to preserve the quality of its visual character.
Triticum durum AGG 1033178 WHEA

Field: Agricultural and Biological Sciences (Life Sciences)

Plant Genetic Resource.
Taxonomy: Triticum durum
Common name(s): Durum wheat
Other names: ICDJMC04-005-BThL(Bulksel)-0sTh-0wTh-0sTh-18wTh-0sTh-0MCH-0MCH[MtAJDSZ][MMkJT]-0AUB
Conserved by: Australian Grains Genebank, DEECA (AGG), Australia
Local sample unique identifier: AGG 1033178 WHEA
Method of creation: Acquisition
Date: 2016-11-03
Historical: No
Biological status: Breeding/research material
MLS status: Included
On the Biology of Werner's Complex

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Werner's Complex, as a cationic coordination complex (CCC), has hitherto unappreciated biological properties derived from its binding affinity to highly anionic biomolecules such as glycosaminoglycans (GAGs) and nucleic acids. Competitive inhibitor and spectroscopic assays confirm the high affinity to GAGs heparin, heparan sulfate (HS), and its pentasaccharide mimetic Fondaparinux (FPX). Functional consequences of this affinity include inhibition of FPX cleavage by bacterial heparinase and mammalian heparanase enzymes with inhibition of cellular invasion and migration. Werner's Complex is a very efficient condensing agent for DNA and tRNA. In proof‐of‐principle for translational implications, it is demonstrated to display antiviral activity against human cytomegalovirus (HCMV) at micromolar concentrations with promising selectivity. Exploitation of non‐covalent hydrogen‐bonding and electrostatic interactions has motivated the unprecedented discovery of these properties, opening new avenues of research for this iconic compound.
Denominational Schools in the Netherlands

Field: Social Sciences (Social Sciences)

This chapter is devoted to the Dutch school system. We shall present and discuss this system quite extensively and from different perspectives. The Dutch school system is unique in the world, but uniqueness naturally does not imply worth and value, nor a system which is unquestionable or unproblematic. We think we can elucidate some general questions about separate schools by focusing on our system and its history.
A systematic review of entrepreneurship education in higher education as panacea to unemployment reduction in South African graduates

Field: Business, Management and Accounting (Social Sciences)

This discursive study explores the attempt to create feasible job creations for young graduates from various higher education institutions across South Africa. A systematic review of various literature sources on the phenomenon argues that entrepreneurship education can create and develop in students creative and innovative, business initiatives, risk-taking, strategic business minds, appropriate decision-making, and opportunities in diverse entrepreneurship activities, after graduation. The integration of entrepreneurship education into higher education across South African Higher Education will boost national economic development. The existing Department of Higher Education's initiative of Entrepreneurship Development into the country's Higher Education requires assessment and repositioning for effective approaches that can actualize the objectives of the initiative. The study recommends the need for universities' managements to re-strategise and connect theory with practical, in diverse significant collaborations with various private businesses, government institutions, and Non-Governmental Organisations.
The relationship between pre weaning social behaviour and racing performance in Thoroughbred horses

Field: Veterinary (Health Sciences)

Vast sums of money are invested in training racehorses, yet race earnings rarely cover training costs. The ability to accurately predict potential racing performance prior to training would be advantageous. Although a link between equine behaviour and later racing success has been suggested, no single measure has yet been identified, mainly due to the complex relationships between behavioural attributes, particularly those of a social nature. The influence of gender is also unclear. According to The Mental Health Model of Sport Performance a degeneration in mental state is reflected by a decline in performance. The success of over 70% of human athletes was identified using behavioural measures of personality. Reportedly equine ‘winners’ are ‘calm’ whilst ‘losers’ are ‘aroused’. Such equine ‘reactivity ‘ (‘temperament’) has traditionally been investigated using contrived experiments. This study aimed to carefully examine equine social activity by exploring multiple aspects of social behaviour whilst avoiding the restrictive concept of dominance.
Navigation Solution to Maneuver Spacecraft Relative to Spheres Centered on Cooperative Satellites

Field: Physics and Astronomy (Physical Sciences)

A differential correction algorithm is presented to deliver an impulsive maneuver to a satellite to place it within the overlapping spheres, with user-defined radii, centered around multiple cooperative satellites within a constrained time. The differential correction algorithm develops and utilizes the state transition matrix along with the equations of motion and multiple satellites’ state information to determine the optimum trajectory to achieve the desired results. The results from the algorithm are presented for prograde orbits. The results are presented in order to allow for mission design trade-offs, including satellite separation distance and required based on the satellites’ initial inclinations. The results also provide empirical methods to determine the miss distance and optimum solutions for the provided problem. This work ultimately provides the framework for applying the algorithm to a unique user defined responsive space scenario.
[DOWNLOAD] Measure and Construction of the Japanese House [Full]

Field: Arts and Humanities (Social Sciences)

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