jimnoneill/paper-to-field-training huggingface dataset:
Comparison between the Patterns of Common Breast Diseases Presenting as Breast Lumps in Pregnant and Non-Pregnant Married Women

Field: Medicine (Health Sciences)

Background: Breast lump is one of the most common prevalent complaint of patients attending breast clinics. Objective: To determine if there is any change in the pattern of common breast, diseases presenting as breast lumps between pregnant and non-pregnant women among patients attending Al-Elwiya Breast Clinic. Methods: This is a cross – sectional study, with convent's patient sampling setting in AL-Elwiya Breast Cancer Early Detection Clinic from 1st Feb. to 1st May 2018, we collected data from patients with breast lumps including the age groups, pregnancy status, parity status, previous breast diseases, hormonal drugs, menstrual cycle, breast feeding. Breast lump was examined, sonography and needle biopsy, and histopathology. Results: This study involves 306 married patients, fibro adenoma was the commonest pathology in the age group 20-29 year-old (29.9%) followed by Aberration of Normal Development and Involution which was found mainly in 30-39-year-old age group (36.1%). Carcinoma found mainly in the >40-year-old age group (10.3%). Aberration of Normal Development and Involution was the main pathology in non-pregnant patients (36.1%), in pregnant patients fibro adenoma is the commonest (35.7%). Conclusion: The majority of breast lumps are benign. In pregnant women, fibro adenoma is the commonest, while in non-pregnant women, Aberration of Normal Development and Involution is the main cause of breast lumps
VP23.12: Oxidative stress biomarkers in amniotic fluid decrease throughout the pregnancy

Field: Medicine (Health Sciences)

Oxidative stress (OS) is associated with poor perinatal outcomes but little is known regarding the levels of OS biomarkers in the fetus along the pregnancy. The aim of this study was to evaluate changes throughout the pregnancy in OS biomarkers in amniotic fluid. This is a retrospective study including 92 amniotic fluid samples, 50 cases from fetuses with a diagnosis of isolated major congenital heart defect and 42 controls (fetuses with high risk of genetic anomaly or extracardiac malformations except CNS or renal anomalies). All the samples were collected from 2016 to 2020 at the time of performing the genetic study and after obtaining the consent of all the patients. Five protein oxidation biomarkers, including orto-tyrosine (o-tyr), metatyrosine (m-tyr), 3NO2-tyrosine (3NO2-tyr), 3I-tyrosine (3I-tyr), were analysed to obtain preliminary data on the OS status of the fetuses, focusing on the correlation between the biomarkers and the gestational age. Samples were analysed using an Acquity-Xevo TQ system. Samples were obtained from 16–38 weeks of pregnancy. We found a negative correlation between gestational age and the following OS biomarkers (figure 1): oTyr (r=-0.5208, p = 0.0001), p-Tyr (r = -0.69, p = 0.0001), Phe (r = -0.7405, p = 0.0001) and NO2-Tyr (r = -0.2268, p = 0.0392). Levels of Cl-Tyr did not vary with gestational age. Our preliminary data demonstrates that there is a correlation between some OS biomarkers and gestational age, supporting the idea of longitudinal changes in OS status throughout gestation. Further studies are needed to identify other potential factors that could influence amniotic fluid concentration of OS biomarkers. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
European Committee of Social Rights: The right to a healthy environment

Field: Social Sciences (Social Sciences)

The European regional system for the protection of human rights has focused, traditionally, on civil and political rights, with less emphasis on social, economic, and cultural rights. The collective complaint mechanism of the European Social Charter 2 may have the potential to change this. Inaugurated in 1998, the procedure has produced a number of decisions with far-reaching implications for law and policy in the Charter’s member states. In the case under review, the European Committee of Social Rights dealt with the right to
Gene expression profiling reveals multiple protective influences of the peptide alpha-melanocyte-stimulating hormone in experimental heart transplantation

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Novel therapies are sought to increase efficiency and survival of transplanted \norgans. Previous research on experimental heart transplantation showed that \ntreatment with the anti-inflammatory peptide alpha-melanocyte-stimulating hormone \n(alpha-MSH) prolongs allograft survival. The aim of the present research was to \ndetermine the molecular mechanism of this protective activity. Gene expression \nprofile was examined in heart grafts removed on postoperative days 1 and 4 from \nrats treated with saline or the synthetic alpha-MSH analog Nle4DPhe7 \n(NDP)-alpha-MSH. On postoperative day 1, the peptide induced expression of \ncytoskeleton proteins, intracellular kinases, transcription regulators, \nmetallopeptidases, and protease inhibitors. Conversely, NDP-alpha-MSH repressed \nimmune, inflammatory, cell cycle, and protein turnover mediators. Later effects \nof alpha-MSH treatment included down-regulation of oxidative stress response and \nup-regulation of ion channels, calcium regulation proteins, phosphatidylinositol \nsignaling system, and glycolipidic metabolism. NDP-alpha-MSH exerted its effects \non both Ag-dependent and -independent injury. The results indicate that \nNDP-alpha-MSH preserves heart function through a broad effect on multiple \npathways and suggest that the peptide could improve the outcome of organ \ntransplantation in combination with immunosuppressive treatments.
Stenosis of Renal Artery: An Unselected Necropsy Study

Field: Medicine (Health Sciences)

Over 50 years ago Janeway (1909) demonstrated an elevated blood-pressure level in the dog after constriction of the renal artery, an observation which was subsequently elaborated by Goldblatt et al. (1934).Since these studies the concept of renal hypertension has become firmly entrenched in the medical literature, and with the advent of improved techniques in radiology and reconstructive arterial surgery renal stenosis has assumed a new significance.But surgical intervention in patients with presumptive renal ischaemia and a raised arterial pressure by either nephrectomy or arterial reconstruction has produced variable results (Braasch, 1942 ;Smith, 1956Kincaid-Smith, 1961).With an ever-increasing interest in renal stenosis as a possible and remediable cause of hypertension in man, it is essential that the frequency and distribution of this lesion in both normo- tensive and hypertensive patients be clearly defined.Sutton et al. (1961) have shown radiologically demonstrable stenosis in 10% of 260 hypertensive subjects investigated by aorto- graphy.Eyler et al. (1962) reviewed a selected series of 500 patients, and found radiologically normal renal arteries in 75 out of 196 hypertensive subjects, and in 206 out of 304 normo- tensives.These workers emphasized that radiological renal artery stenosis, even with post-stenotic dilatation, can occur in normotensive subjects.So far the few pathological studies reported have not clarified the picture.Blackman (1939) reported the necropsy findings in 50 cases with "hypertension" and 50 "controls" whose age and mode of selection were not defined, save that they were not hypertensive and had no cardiac hypertrophy.In his series the whole length of the renal arteries was not always available for study.Other studies include those of Richardson (1943), Lisa et al. (1943), and Holley et al. (1962).The latter authors concluded that renal arterial stenosis was common in both hypertensive and normotensive subjects aged 50 and over.In this unselected necropsy study we have determined the prevalence and distribution of renal arterial stenosis in both the extrarenal and intrarenal segments of the arterial tree.The relation of stenosis to various clinical and pathological parameters is discussed. Composition of the Necropsy SampleDuring the years 1962-3 an unselected series of kidneys and renal arteries was obtained from 154 patients on whom necropsies were performed in the Royal Adelaide Hospital.This sample included all cases presenting on consecutive Wednesdays and alternate Sundays.Relevant dinical details including casual blood-pressure measurements were obtained
Optical Mapping System for Visualizing Arrhythmias in Isolated Mouse Atria

Field: Medicine (Health Sciences)

Optical mapping has become an important technique in the study of cardiac electrophysiology, especially in terms of investigating the mechanisms of cardiac arrhythmias. The increasing availability of transgenic mice as models for cardiovascular disease is driving the need for instrumentation suitable for the study of electrical activity in the mouse heart. In this paper we evaluate our optical mapping system's ability to clearly record induced arrhythmic activity in an isolated mouse atrial preparation. Preliminary results indicate that the signal quality is high enough that individual optically recorded action potentials can be discerned in many pixels, even without post-processing for noise removal. The optical mapping video is clear enough for general observations regarding the patterns of electrical propagation during arrhythmic behaviour. The induced arrhythmias appear to have a regular pattern of activity, and are likely best classified as atrial tachycardias.
Effects of plowing on the growth of seminal and nodal roots and on root branching of maize (<i>Zea mays</i> L.) in upland fields converted from paddy fields in Andosol

Field: Agricultural and Biological Sciences (Life Sciences)

これまでの研究から，ロータリ耕と比較してプラウ耕 （チゼルプラウで粗耕起後にパワーハローで砕土する体系） における土壌深さ8 cm以深の土壌は硬く，肥料が土壌表層に集中し，トウモロコシの根系はプラウ耕による土壌硬度の影響でロータリ耕と比べて第7葉期以降に浅根化することが明らかとなった．そこで，黒ボク土の水田転換畑におけるプラウ耕がトウモロコシの種子根と節根に及ぼす影響を調べ，浅根化した要因を解析した．試験は，施肥区と無施肥区を設けてロータリまたはチゼルプラウ （プラウ） で耕起し，土壌表層 （土壌深さ0-10 cm） の根系を調査した．ロータリ耕に比べてプラウ耕では，第3葉期までと乳熟期の種子根の根長密度は低かったが，第6葉期以降の節根の根長密度は高く，節根の分枝根が第6葉期と雄穂形成期で多く，乳熟期の節根の1次根長も長かった．第6葉期以降に種子根の根長密度は減少するが，節根の根長密度は増大し，さらに耕起法の違いによりロータリ耕よりプラウ耕で増大することから，プラウ耕による浅根化の要因は耕起法の違いが節根の伸長と分枝に影響を及ぼしたためと結論された．
EMPOWERING MEDAN ART COMMUNITY THROUGH DEVELOPING GRAFFITY WRITING AS CREATIVE INDUSTRY MODEL (THE LOCAL WISDOM OF MALAY DELI)

Field: Arts and Humanities (Social Sciences)

This paper promotes a concept to empower Medan art community through the development of writing graffiti as a media of creative industry entrepreneurs based the local wisdom with reintroducing and as well as maintaing the local wisdom of the Pantuns of Malay Deli. The method of this paper is an ethnographic method, using a qualitative descriptive approach. The data on this paper are obtained using observation and interview. The analysis of this paper are: (1) The pantuns of Malay Deli that have the local wisdom values of cultural behaviors for general public environment which consists of cleanliness, security, orderliness, beauty and kinship values. And (2) the iconic character of Mr. Belalang as a characteristic figure in the Malay story as an icon to introduce, inspire and form the distinctive personality as well as embody the instilling of high cultural values for the culture of the terrain community. The result of this paper are that (1) Marchandise or sourvenirs using the pantun of Malay Deli with the icon of Mr. Belalang as a form of creative industry based on local wisdom of Malay deli culture, (2) The place of graffiti writing as a media for developing Medan art community in expressing creativity based on local wisdom of Malay Deli. Briefly, the model of graffiti writing as a media for empowering Medan art Community in reintroducing and maintaining the culture of Malay Deli which are applied effectively as the form of creative industry entrepreneurs based the local wisdom.
Predictive Value of Maternal Serum Level of Procalcitonin in Diagnosing Chorioamnionitis in Mothers with Preterm Premature Rupture of Membrane (PROM)

Field: Medicine (Health Sciences)

Background: Premature Rupture of Membrane (PROM) refers to the rupture of fetal membranes at least 1 hour before the onset of labor pain. The present study intended to determine the predictive value of maternal serum level of Procalcitonin in the early diagnosis of Chorioamnionitis in mothers with PPROM.Methods: In this prospective cohort study, a total of 48 patients with PPROM were selected as the intended sample size due limited financial resources and in accordance with previous articles in Kosar ward of Motahhari hospital of Urmia city, Iran. Inclusion Criteria were amniotic fluid leak, positive Nitrazine and Fern test, gestational age from 28 to 33 weeks and lack of fetal tachycardia. Exclusion Criteria were chronic and congenital heart disease as well as use of NSAIDs. Data were analyzed using SPSS 19 and descriptive statistics, independent t-test and Pearson test were performed.Results: The present study was conducted on 48 pregnant women and their neonates. About %39.6 of mothers was pathologically infected with Chorioamnionitis while %60.4 of the patients were not infected with the disease. Moreover, %68.8 of the neonates had a five-minute Apgar score of ≥7. There was a significant correlation between infection of mothers with histopathologic Chorioamnionitis and neonatal hospitalization in NICU (P<0.001). The sensitivity, specificity, positive and negative predictive values of PCT inflammatory index were %100, %79, %57.5 and %100 respectively for the diagnosis of histopathologic Chorioamnionitis.Conclusion: It was found that there was a significant correlation between PCT index at delivery time and histopathologic Chorioamnionitis.
341: Renal Preservation in upper Tract Transitional cell Carcinoma (UTTCC) Patients Treated with Percutaneous Resection. - 20 year Experience

Field: Medicine (Health Sciences)

You have accessJournal of UrologyPodium 12, Sunday, May 20, 2007 10:00 am - 12:00 pm1 Apr 2007341: Renal Preservation in upper Tract Transitional cell Carcinoma (UTTCC) Patients Treated with Percutaneous Resection. - 20 year Experience Ardeshir R. Rastinehad, Michael C. Ost, Kathryn L. Greenberg, Brian A. VanderBrink, Benjamin R. Lee, Gopal H. Badlani, and Arthur D. Smith Ardeshir R. RastinehadArdeshir R. Rastinehad More articles by this author , Michael C. OstMichael C. Ost More articles by this author , Kathryn L. GreenbergKathryn L. Greenberg More articles by this author , Brian A. VanderBrinkBrian A. VanderBrink More articles by this author , Benjamin R. LeeBenjamin R. Lee More articles by this author , Gopal H. BadlaniGopal H. Badlani More articles by this author , and Arthur D. SmithArthur D. Smith More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)30606-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "341: Renal Preservation in upper Tract Transitional cell Carcinoma (UTTCC) Patients Treated with Percutaneous Resection. - 20 year Experience." The Journal of Urology, 177(4S), p. 115 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 177Issue 4SApril 2007Page: 115 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Ardeshir R. Rastinehad More articles by this author Michael C. Ost More articles by this author Kathryn L. Greenberg More articles by this author Brian A. VanderBrink More articles by this author Benjamin R. Lee More articles by this author Gopal H. Badlani More articles by this author Arthur D. Smith More articles by this author Expand All Advertisement PDF downloadLoading ...
Tricuspid Valve Surgery without Transplanting Transvenous Pacing Systems

Field: Medicine (Health Sciences)

リードが三尖弁に悪影響を及ぼすことは数多く報告されている．特に徐脈性心房細動に対してリードを挿入している症例は，三尖弁逆流をきたすことが多く注意が必要であるが，逆流が進行してもリードが原因であり，仕方がないと判断され，著明な右心不全状態になるまで経過観察されることがしばしばある．このような状態での手術は非常にリスクが高く成績は不良である．一般的には経静脈リードを抜去し心外膜へ移設した後三尖弁手術を行うが，われわれは，経静脈リードをそのままにして三尖弁手術を行っている．リードを自然な走行で移動可能な交連部へ固定した後に弁形成術や置換術を行うことで，リード抜去による右心室損傷のリスクや閾値の問題を回避することができる．またリードが入ったままでも三尖弁手術は可能であるということが，至適時期に治療を行うための後押しとなるのではないかと考えている．
Patient perspective: coping with preoperative anxiety in patients scheduled for coronary artery by-pass surgery. A mixed-methods study.

Field: Health Professions (Health Sciences)

Background Despite substantial literature that addresses preoperative anxiety, identifying effective anxiety-management interventions is still recommended. Identifying factors related to preoperative anxiety is essential for intervention planning. Aim To explore patient-reported factors contributing to decreased anxiety among patients scheduled for coronary artery by-pass grafting (CABG). Methods This mixed-methods observational study involved 75 patients aged 40-83 (70.7% men; mean age 65.4±9.41). Qualitative analysis involved 25 randomly selected patients (focus group) and asked to specify factors they believed were helpful in reducing their anxiety. Visual Analogue Scale (VAS-Anxiety) was used at the moment of diagnosis and decision making (Time1, retrospectively), and on the day preceding CABG (Time2). Focus group responses were explored with the use of Interpretative Phenomenological Analysis (IPA). The Pearson’s chi - squared and the Mann-Whitney-U tests were calculated to explore differences between the study groups. Significance level α≤0.05 was used in all analyses. Results VAS-Anxiety scores reduced from 5 points at Time1 to 3 points at Time 2 (p<0.01). Fifty patients (66.7%) reported decreased anxiety between Time1 and Time2, 21 (28%) reported a stable level and 4 (5.3%) reported an increase. Employment status was the only significant factor differentiating “relief’ and “no relief” groups among socio-demographic and clinical variables. IPA yielded five main themes: conversations with health care providers, perceived inevitability of surgery, family support, other patients’ experience, and religion/faith. Conclusions Individual patient-centered interview in conjunction with emotional support are vital for managing preoperative anxiety. Providing contact with family members and paying attention to spiritual needs are also important.
Antibodies to Candida albicans in hospital patients with and without spinal injury and in normal men and women

Field: Medicine (Health Sciences)

The presence of serum agglutinins and precipitins to Candida albicans in men and women who had impaired bladder function following spinal injury is compared with that in other patients in hospital and in apparently fit men and women. Antibody levels which have commonly been regarded as significant were found in 35 of 76 patients who had urinary candidiasis; in 10 of 52 patients who had spinal injury without urinary candidiasis; in eight of 57 patients who had neither of these conditions, and in nine of 191 normal men and women. Observations are made on the antigens involved in these reactions and on the need for standardization of both reagents and techniques.
Influence of Different Modes of Oxygenation of the Small Intestinal Mucosa in vitro on Glucose and Maltose Accumulation

Field: Medicine (Health Sciences)

Glucose accumulation by the everted sacs of the rat small intestine has been investigated during mucosal, serosal and bilateral oxygenations. The condi­ tions are described under which active accumulation of glucose is provided by serosal but not only mucosal oxygenation. It has been found that the active accumulation of glucose during the bilateral oxygenation is approximately equal to the sum of those during the serosal and mucosal oxygenations. The relative roles of the serosal and mucosal modes of oxygenation vary in the fed and fasting animals, as well as in the different segments of the small intestine. The results obtained may be explained by the hypothesis on the existence of two types of cell respiration — apical and basolateral.
Study on Road Durability of Multilevel Built-In Waterborne Epoxy Micro-Surfacing

Field: Engineering (Physical Sciences)

Micro-surfacing has been commonly used in engineering applications as a preventive maintenance technology. However, given its low temperature stability and insufficient adhesion between layers, micro-surfacing leads to the insufficient durability of pavements and shows poor resistance to flaking and rutting, easy to scatter, etc. Although the aggregate meets the requirements, micro-surfacing has an unreasonable gradation. Moreover, despite satisfying the requirements, the emulsified asphalt lacks bond strength, high temperature stability, and rutting resistance. To address these limitations, this study proposes a design method using multilevel dense built-in gradation waterborne epoxy micro-surfacing and investigates the main factors that affect road performance to improve the road durability of micro-surfacing. The particle size characteristics of different proportions of waterborne epoxy and emulsified asphalt mixtures were analyzed via laser particle size analysis test to study the curing time of waterborne epoxy resin (WER). According to the design system of the multilevel dense built-in gradation (MDBG) and the Bailey method, three types of micro-surfacing gradation were designed. The relationships of gradation, oil-stone ratio, and WER content with the abrasion and water resistances of micro-surfacing were tested by conducting 1 h and 6 d wet wheel abrasion tests. Results show that the curing of WER involves two stages, and that the blend ratio affects the curing time. The coarse aggregate ratio RCAof MDBG can be used to design different gradations, and RCAshould be set between 0.5 and 1.0. The application of WER can improve the mixture abrasion and rutting resistance of micro-surfacing, whereas an appropriate aggregate gradation, oil-stone ratio, and curing time are identified as prerequisites for WER with an optimum content of 5.0% to 7.0%.