jimnoneill/paper-to-field-training huggingface dataset:
Cloning of a novel thioredoxin gene( ScTRXh2),responsive to abiotic stresses,in sugarcane

Field: Agricultural and Biological Sciences (Life Sciences)

A full-length cDNA sequence of thioredoxin gene with a length of 752 bp and open reading frame( ORF) 381 bp,designated as ScTRXh2( GenBank Accession No. KF921298),was isolated from sugarcane stem full-length cDNA library. The ScTRXh2 was predicted to encode 126 amino acid residues,and its deduced amino acid sequence shared a high degree of homology with Arabidopsis TRXs. The length of 5' non-translated region and 3' non-translated region were 57 bp and 314 bp,respectively. The expression profiles of ScTRXh2 detected by real-time qPCR in different sugarcane organs showed to be a constitute expression,and the expression levels in leave and stems were significant higher than those in roots and buds. The expression profiles of ScTRXh2 responsive to H2O2and PEG stresses detected by Q-PCR were similar,which is slightly down-regulated at initial stage( 3 h),significantly up-regulated at early to middle stages( 6 h or 12 h) and significantly down-regulated with a steadily low expression at middle to later stages( 12 h,24 h,48 h and 72 h for H2O2stress or 24,48 and 72 h for PEG stress). Though the expression profiles of ScTRXh2 appearing to be significantly up-regulated at middle stage( 12 h) and significantly down-regulated with a steadily low expression at later stages( 24 h,48 h and 72 h),the expression of ScTRXh2 responsive to NaCl stress was faster than that in H2O2or PEG stress and the expression profile was obviously different with a significantly up-regulated at initial stage( 3 h). It was suggested that the ScTRXh2 gene was actively responsive to the abiotic stresses of H2O2,PEG and NaCl,but there was difference in the responsive rapidness and the expression profiles.
Cancer patients’ experiences of living with venous thromboembolism: A systematic review and qualitative thematic synthesis

Field: Medicine (Health Sciences)

Background: Cancer-associated thrombosis is common. Recommended treatment is daily injected low-molecular-weight heparin for 6 months. Most studies focus on prophylaxis and treatment; few have explored the patients’ experience. Aims: To identify and synthesise the available literature concerning patients’ experience of cancer-associated thrombosis. Design: Systematic literature review and qualitative thematic synthesis. Data source: MEDLINE, Embase, CINAHL, PsycINFO (until 10/2016; limited to English) were searched. Eligible papers were qualitative studies of adult patients’ experience of cancer-associated thrombosis. Two researchers screened titles/abstracts/papers against inclusion criteria with recourse to a third for disagreements. Critical Appraisal Skills Programme qualitative checklist tool was used for quality appraisal. Results: A total of 1397 articles were identified. Five qualitative studies (total n = 92; age range 32–84 years) met the inclusion criteria. Participants had various cancer types. Most had advanced disease and were receiving palliative care. Four major themes emerged from the data: knowledge deficit (patients and clinicians), effects of cancer-associated thrombosis (physical and psychological), effects of anticoagulation and coping strategies. Conclusion: The cancer journey is difficult in itself, but thrombosis was an additional, frightening and unexpected burden. Although the association between cancer and thromboembolism is well-known, cancer patients are not routinely educated about the risk or warning symptoms/signs of thromboembolism which may otherwise be misattributed to the cancer by patient and clinician alike. This systematic review highlights the impact of cancer-associated thrombosis on the lives of cancer patients, and calls for education for patients and clinicians to be part of routine care and further work to address this patient priority.
A Great Leap Forward: 1930s Depression and U.S. Economic Growth

Field: Economics, Econometrics and Finance (Social Sciences)

Alexander J. Field presents a convincing case for a “novel claim: potential output grew dramatically across the Depression years” (p. 1). As a result, his book is a compelling argument that the record-high total productivity gains (or total factor productivity [tfp]) of 1929–1941 were the real bases for the successes of the war economy and for the “golden age” (1948–1973) of mass consumer prosperity (p. 106). The first and longest part of this important book is a significant revision of economic history since the Civil War titled “A New Growth Narrative.” Its six chapters are an exemplary demonstration of how careful and imaginative use of statistical information can revise deeply entrenched ideas about the past. Ordering his data into business-cycle peak-to-peak periods, Field is able to make a series of meaningful comparisons that highlight the positive developments of 1929–1941 usually overlooked by historians seeking to explain the persistent high levels of unemployment that justify labeling those years the Great Depression.
International Jurisdiction on Fighting Against Corruption

Field: Social Sciences (Social Sciences)

The urgency of the article is stipulated by the importance to form international legal institutes aiming at fighting against corruption and the problem related to implementing international regulations of the anti-corruption purposefulness in national legal systems. The use of formal legal methods allowed to research the following groups of the most important anti-corruption regulators: international anti-corruption standards and principles, international and legal mechanisms of monitoring the fulfillment of anti-corruption conventions, and international legal measures to prevent corruption. Empiric data show that the lack of the system counteraction to corruption as a negative social and legal phenomenon causes the erosion of legal institutes, and finally, their full non-operability. It is necessary to further integrate international cooperation in this area. It must result in the formation of the standard unanimity of institutes of national jurisdiction in fighting against corruption.
Fine Particle Coating in a Circulating Fluidized Bed by Rapid Expansion of Supercritical Fluid Solutions.

Field: Chemical Engineering (Physical Sciences)

平均粒径56μmのMS触媒粒子を, 内径50mmの内部ノズル付き循環流動層で空気で循環流動させた中に, 超臨界二酸化炭素中に溶解させたパラフィンをノズルから噴出させ, 微粒子コーティングを行った.コーティング量およびコーティング速度はサンプリング法によって測定した.コーティング速度は時間によらずほぼ一定で, 粒子は凝集することなく安定なコーティングが可能であった. SEM観察より, 核粒子表面はパラフィンの微粒子および膜で均一に被覆されていることが確認された.コーティング速度およびコーティング効率は, パラフィン濃度の増加とともに, またガス空塔速度の低下とともに増大したが, パラフィン濃度が大きな領域ではコーティング効率は頭打ちの傾向があることを見いだした.
First Report of Fusicoccum aesculi Causing Leaf Spots of Paeonia suffruticosa in Henan Province, China

Field: Agricultural and Biological Sciences (Life Sciences)

Tree peony (Paeonia suffruticosa) is regarded as the national flower of China and is cultivated throughout the country. In early August 2010, a moderately severe leaf spot was observed on tree peony cultivated in a garden of Zhengzhou, Henan Province, where approximately 15% of trees were diseased. In 2011, a less damaging leaf spot was also observed in another area of the city with approximately 10% of trees diseased. Early symptoms appeared as small, round, pale-brown lesions on the leaves. Lesions expanded into 5- to 20-mm-diameter spots that were elliptical or irregular, brown to dark brown. A fungus was consistently isolated from the leaf spots on potato dextrose agar (PDA) in grey-black colonies, but produced few pycnidia. Black pycnidia were ostiolate, globose, papillate, formed in uniloculate or multiloculate stromata that were immersed in the leaf, and became erumpent at maturity. Conidiophores or conidiogenous cells were hyaline and cylindrical. Conidia were hyaline, granular, fusoid to ellipsoid, aseptate, with a sub-truncate base, and 20 to 28 × 4.5 to 7.5 μm (mean dimensions of 50 conidia: 24.5 × 5.2 μm). The pathogen was identified as Fusicoccum aesculi, anamorphic stage of Botryosphaeria dothidea, on the basis of morphology (2). The identity of the fungus was confirmed to be F. aesculi by DNA sequence analysis of the internal transcribed spacer (ITS) region (GenBank Accession No. JQ323001), which was 100% identical to those of other F. aesculi isolates (GenBank Accession Nos. GU997686.1 and GU723469.1) (1). Pathogenicity tests were done by inoculating each of 10 leaves on one 7-year-old tree with a mycelial plug (0.5 cm diameter) harvested from the periphery of a 7-day-old colony. An equal number of leaves on the same tree, serving as controls, were mock-inoculated with plugs of PDA medium. Inoculated leaves were covered with plastic for 24 h to maintain high relative humidity and incubated at about 25°C. The plugs were removed after 48 h. After 7 days, 80% of the inoculated leaves showed symptoms identical to those observed in the field under natural conditions, whereas controls remained symptom-free. Reisolation of the fungus from lesions on inoculated leaves confirmed that the causal agent was F. aesculi. Pathogenicity tests were repeated on the other two trees by the same methods with the same results. To our knowledge, this is the first report of F. aesculi infecting P. suffruticosa in China. References: (1) S. Mohali et al. Mycol. Res. 110:405, 2006. (2) B. C. Sutton. The Coelomycetes. CABI Publishing, New York, 1980.
What is the evidence behind guideline recommendations to monitor chronic diseases in UK primary care?

Field: Health Professions (Health Sciences)

Background More than half of tests ordered by GP practices are to monitor long-term conditions such as high blood pressure, diabetes, and chronic kidney disease (CKD). There is a large variation in ordered tests between GP practices, suggesting some tests may not be appropriate. Unnecessary testing should be avoided as it can generate anxiety for patients, increase workload for doctors, and increase costs for the health service. Aim The objective was to review monitoring strategies for hypertension, type 2 diabetes, and CKD patients and to investigate the evidence-base underlying these recommendations. Method Current UK guidelines on the relevant diseases were reviewed. Any guidance on the use of laboratory tests for disease monitoring (not including drug monitoring recommendations), the recommended frequency of testing, as well as the level of evidence on which the guidance was based was extracted. Results Guidelines for the use of monitoring tests in primary care for hypertension, diabetes, and CKD are unclear and incomplete; for example, recommended frequency of testing varied between guidelines or was not specified at all. Current recommendations for monitoring chronic diseases are largely based on expert opinion; robust evidence for optimal monitoring strategies and testing intervals is lacking. Conclusion In the absence of clear evidence, clinicians should consider which tests are likely to influence patient management and should ensure that there is a clear clinical rationale for each test that they perform. Future research should address what the optimal strategy for monitoring chronic conditions consists of, and how it can be evaluated.
Outer membrane protein antigens of Moraxella bovis.

Field: Immunology and Microbiology (Life Sciences)

Outer membranes were isolated from bovine isolates and type strains of Moraxella bovis, M phenylpyruvica, M lacunata, and M ovis by sodium N lauroyl sarcosinate extraction and differential centrifugation. Analysis of outer membranes from these organisms by sodium dodecyl sulfate-polyacrylamide-gel electrophoresis revealed that all M bovis isolates shared a common polypeptide pattern that was readily distinguishable from other Moraxella spp. Nine major outer membrane protein bands were identified by sodium dodecyl sulfate-polyacrylamide-gel electrophoresis analysis of M bovis. Immunoblotting of protein antigens of M bovis revealed several outer membrane proteins that seemed to be common antigens of all M bovis isolates.
Evaluation of the proteomic profile in saliva of brazilian home-based and informal workers

Field: Medicine (Health Sciences)

BACKGROUND AND AIM: The Brazilian city of Limeira consolidates a pole of jewelry production with homemade and informal processes of assembly, welding, and electroplating, constituting a scenario of outsourced services. These processes can expose workers to potentially toxic elements (PTE: Hg, Pb, Ni, Cd, Zn, As, Cu, Cr, and Sn), and the productive chain encompasses the related families. This study aimed to evaluate the effects of PTE exposure on protein expression performing a proteomic approach. METHODS: Saliva samples were collected from 26 individuals, Welders Group (n=13) and Control Group (n=13). Blood PTE levels were determined by ICP-MS and saliva samples' proteins by UPLC coupled to a mass spectrometry (Q-TOF), shotgun runs. Bioinformatics analysis was performed using PEAKS Studio 8.5. RESULTS:Significant differences were found for Sn (p0.000004) and Cu (p0.0005) concentrations between the groups. In total, 979 proteins were identified in both groups and, removed the proteins with fifty percent of missing values, and substituted by mean values, 411 proteins. The data was autoscaled, then performed the multivariate analyses using MetaboAnalyst 4.0. Principal components analyses and partial least square discriminate analysis showed a group separation. By t-student test performed, we found 40 significant proteins (p0.05). Gene ontology analysis showed biological processes more represented for viral transcription, maintenance of cell polarity, nuclear-transcribed mRNA catabolic process, and nonsense-mediated decay. Pearson correlation showed 28 significant proteins correlated with metals (p0.05). ARP2 and 1433G proteins were correlated with Pb and Sn. IF4A1, ARF6, RS10, PLBL1 and RS9 correlated with Sb. The proteins MNDA, CRBG1, RAB5B, SAP, LV39, NUCB1, CAPZB, HV64D, IMB1, ARP3, LV743, SPR1A, HV459, HV461, HVD82, HVD34, DDX3X, CDC42, PDIA6, CAN1, TM11D, ARG1, FLNB correlated with Sn. We found 16 of these proteins with greater expression in the Welders group. CONCLUSIONS:The informal, home and outsourced work performed by welders is influencing their internal exposome. KEYWORDS: Proteomics, toxic elements, informal work.
EXPLORING CLOUD-BASED PLATFORMS FOR RAPID INSAR TIME SERIES ANALYSIS

Field: Computer Science (Physical Sciences)

Abstract. The idea of near real-time deformation analysis using Synthetic Aperture Radar (SAR) data as a response to natural and anthropogenic disasters has been an interesting topic in the last years. A major limiting factor for this purpose has been the non-availability of both spatially and temporally homogeneous SAR datasets. This has now been resolved thanks to the SAR data provided by the Sentinel-1A/B missions, freely available at a global scale via the Copernicus program of the European Space Agency (ESA). Efficient InSAR analysis in the era of Sentinel demands working with cloud-based platforms to tackle problems posed by large volumes of data. In this study, we explore a variety of existing cloud-based platforms for Multi-Temporal Interferometric SAR (MTI) analysis and discuss their opportunities and limitations.
[Effect of klotho gene on the endothelial function of spontaneously hypertensive rats].

Field: Medicine (Health Sciences)

The aim of the studies was to investigate klotho gene effect on the endothelial dysfunction of spontaneously hypertensive rats (SHR). In this study, ten SHR and ten normal Wistar rats, all 22 week old, were prepared. After given intraperitoneal anesthesia, the rats' brains, lungs, hearts, kidneys and aortas were removed. The identification was made by means of real-time polymerase chain reaction (Real-time PCR) and Enzyme-Linked Immunosorbent Assay (ELISA). Compared with the normal group, the klotho mRNA and protein in SHR were less than those in the control group with normal corresponding values, while Endothelin-1 (ET-1)'s mRNA and protein were more than those of normal group. The analysis of the correlation of mRNA and protein in heart and aorta revealed that klotho gene was negatively correlated to ET-1. The results showed that klotho significantly decreased in SHR, which might be influenced by hypertension-induced damage on the endothelial function.
CHI's 18th Annual Discovery on Target. Virtual - September 16-18, 2020

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The Cambridge Healthtech Institute (CHI) continued its annual Discovery on Target series of conferences as a virtual platform due to the COVID-19 pandemic preventing live attendance at large events This, the 18th annual conference, continued the multitrack format, providing coverage of a wide range of targeting topics, including RNA, PROTACs, antibodies, proteins, immunology and oncology, nonalcoholic steatohepatitis, fibrosis, models, cell/gene therapy, kinase inhibitor and GPCR-based drug discovery, biomarkers Along with live and on-demand presentations, all with potential for QAa virtual exhibit hall was also created This report will cover some of the presentations given relating to drug discovery and potential targets Copyright © 2020 Clarivate Analytics
Effects of Ginkgolide B and Ginkgo biloba extract on local cerebral glucose utilization in the awake adult rat

Field: Neuroscience (Life Sciences)

Abstract The effects of the extract of the leaves of Ginkgo biloba and of one of its major components, Ginkgolide B, on local cerebral glucose utilization (LCGU) have been studied in the awake adult rat. Ginkgolide B (10 mg/kg i.p.) had no significant effect on LCGU in 38 brain regions studied. In contrast, the Ginkgo biloba extract (150 mg/kg i.p. in 3 divided doses) produced significant and widespread decreases in LCGU in 21 brain regions (range 3–26% reduction). These results demonstrate that Ginkgo biloba is able to reduce brain glucose utilization, but that the substance responsible for this effect may not be Ginkgolide B.
Advertising and Investor Recognition of Banking Firms: Evidence from Taiwan

Field: Economics, Econometrics and Finance (Social Sciences)

This study examines the effect of advertising expenditure on strengthening a firm’s intangible capital and firm value by attracting the public on the firm’s visibility and then investigates the role of advertising expenditures on a banking firm’s market value, liquidity, and breadth of ownership. The empirical results find that the advertising has a significantly positive effect on banking firm’s share value, liquidity, and institutional holdings. Consequently, this study concludes that advertising benefits banking firms through increased investor perceptions of such firms. In particular, the findings provide additional support for the home bias phenomena, in which investors prefer to invest in familiar stocks.
Chromosome banding in Cacopsylla mali (Schmidberger) and Cacopsylla sorbi (Linnaeus) (Homoptera, Psyllidae) with polymorphic sex chromosomes.

Field: Agricultural and Biological Sciences (Life Sciences)

C-banding and Ag staining were applied to Cacopsylla sorbi and C. mali. The aim was to discover some additional cytological markers to follow the pathways of the sex determination system transformation in the evolution of the species. Of three karyotype patterns so far described in the literature for these species--a type A (XO), B (neoXY) and C (neoX1X2Y), only the last two types (B and C) were found. All 6 studied Cacopsylla sorbi from Finland had a karyotype of type B (2n = 20 + XY), while C. mali had both types. Type B (2n = 22 + XY) was observed in 31 males, whereas type C (2n = 20 + neoX1X2Y) in the remaining four. The karyotype of C. sorbi was found to be characterized by a very small amount of C-positive material, localized in a telomere of the Y chromosome. The karyotype of C. mali was also characterized by a very small amount of C-banded material. Both the sex chromosomes and the autosomes displayed a marked polymorphism of C-positive bands within different individuals and even the same individual. In both species the nucleolus was located in the telomere of a middle sized autosomal till diplotene inclusive. The C-banding and Ag staining in the studied Cacopsylla species did not provide any additional cytological markers for an understanding of the pathways of sex determination system transformation in the evolution of the species.
Bounded Self-motion of Functional Redundant Robots

Field: Engineering (Physical Sciences)

In this paper, we consider a problem how to exploit a task
space motion for lower-priority tasks when the end-effector motion allows
some deviation of the motion for the primary task. Using a common
redundancy resolution methods, the self-motion is only possible in the
null-space. Therefore, we propose a novel combination of controllers in
two spaces: in the task space and in the reduced task space, where DOFs
corresponding to spatial directions allowing the deviations are excluded.
The motion generated by the controller in the reduced task space is
mapped into the main task and by properly selecting the controller
parameters the resulting motion does not violate the constraints. To
demonstrate the effectiveness of the proposed control we show simulation
examples where motion in a constraint region is used to avoid joint
limits.
Qualidade dos Dados no Programa Dinheiro Direto na Escola (PDDE): Superando o Desafio do Garbage In, Garbage Out (GIGO)

Field: Social Sciences (Social Sciences)

Introduction: The investigation presents and discusses the relevance of data quality in Data Science, introducing the concept of "Garbage In, Garbage Out" (GIGO) to the Money Direct to School Program (PDDE). Objectives: The objective was to describe the process of data extraction, transformation, and loading for the generation of information panels by the Collaborative Support Center for Monitoring and Management of Educational Programs (CECAMPE/NE). Methodology: The employed methodology was quantitative and used typical Data Science tools. The data related to the PDDE were collected from transactional systems and surveys with the involved populations. Results: The results showed a satisfactory reduction of GIGO, although challenges were identified such as data update discrepancies, lack of adequate documentation of data tables, and issues with free typing fields in survey forms. Conclusion: The analysis reiterates that the GIGO concept is a significant challenge for the effective use of PDDE data and emphasizes the need to develop better data management practices in the context of the program. It suggests that all professionals who use data as raw material for their professional activities should be aware of these challenges and work towards effective solutions.
Research Article Neuroprotective Properties of a Novel Non-Thiazoledinedione Partial PPAR-

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Copyright © 2013 Christine R. Swanson et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Activation of the peroxisome proliferator activated receptor-gamma (PPAR)-
Environmental Harm and Financial Responsibility

Field: Economics, Econometrics and Finance (Social Sciences)

Firms will exert too little care due to a limited liability effect if damages are likely to exceed their equity. This is particularly important for environmental and product liability and motivates the current discussion about mandatory insurance and extending liability to creditors. We model the choice of the care level as a moral hazard problem that can be solved through costly monitoring. Conventional strict liability and lender liability both lead to distortions in the capital structure and to inefficiently low care. By contrast, mandatory liability coverage (financial responsibility) that can be satisfied by either an insurance contract or a lender guarantee leads to the first best allocation if managers can self-insure, and to the second best if managers cannot self-insure but choose to be monitored.