jimnoneill/paper-to-field-training huggingface dataset:
Investment portfolio balancing: application of a generic self‐organizing fuzzy neural network (GenSoFNN)

Field: Computer Science (Physical Sciences)

Abstract In contrast to short‐term stock trading, portfolio managers are interested in the medium‐ to long‐term peaks and troughs of the stock price cycles as signals to balance their stock portfolios – the predicted trough is the signal to buy the stock and the predicted peak is the signal to sell the stock. As statistical models are generally inadequate or incapable of providing such portfolio balancing signals, we propose using the generic self‐organizing fuzzy neural network (GenSoFNN)—a fuzzy neural system – as a tool for portfolio balancing. The network adopts the supervised learning approach to detect inflection points in the stock price cycles, and a modified locally weighted regression algorithm is employed to smooth the stock cycles. The GenSoFNN‐based portfolio balancing system was evaluated with experiments conducted using 23 stocks from the New York Stock Exchange and NASDAQ, and the results showed an average profit return of 65.66%. The contributions of the proposed GenSoFNN intelligent portfolio balancing system are twofold: it can be used as an efficient trading solution and it can provide decision support in trading via its generated rules. Copyright © 2009 John Wiley & Sons, Ltd.
The oration "Non habet me dubium" of Enea Silvio Piccolomini (11 January 1447, Rome)

Field: Arts and Humanities (Social Sciences)

In January 1447, Enea Silvio Piccolomini was sent by Emperor Frederick III to the ailing Pope Eugene IV. His mission was to declare the obedience of the Holy Roman Empire to the Pope, thus ending the state of German neutrality between the Pope and the Council of Basel. This Council had been dissolved by the Pope in 1438, but it continued to function and even elected a counter-Pope, Felix V. Piccolomini was accompanied by other ambassadors from German princes and prelates with the same purpose. The Germans posed a number of conditions to be met by the Apostolic See before obedience could be declared: holding a new General Council, recognizing the authority of the General Councils, removing the financial and legal burdens on the German Nation, and lifting the excommunication of the Archbishops of Cologne and Trier. The mission was successful, but the Pope did not himself enjoy the fruits of this victory for the papacy since he died some weeks later. As a reward for his diplomatic success, Piccolomini was, soon after, appointed Bishop of Trieste.
Adverse events following immunization (AEFI) with the novel influenza a (H1N1) 2009 vaccine: findings from the national registry of all vaccine recipients and AEFI and the passive surveillance system in South Korea

Field: Medicine (Health Sciences)

This study characterized the adverse events following immunization (AEFI) with the novel influenza A (H1N1) 2009 vaccine in Korea. Data on immunization and AEFI were collected between October 27, 2009 and March 15, 2010 through the national immunization registry and passive surveillance systems. The frequency of AEFI and serious adverse events (SAEs) were calculated according to age, sex, priority group, and vaccine type. In 13,758,527 vaccine recipients aged 6 months or older, 2,530 AEFI were reported (18.4 per 100,000 immunizations). The AEFI reporting rate was highest among people aged 10-19 years (29.6 per 100,000 immunizations) and was higher in female recipients than in male recipients (20.0 versus 16.7 per 100,000 immunizations). Most AEFIs were nonspecific systematic reactions that occurred within 24 h (77.4%) after vaccine administration. A total of 178 vaccine-related SAEs were identified, and vaccine-related mortalities were not reported. This study showed that the AEFI reporting rate after influenza A (H1N1) 2009 vaccinations was relatively high, especially in the younger population. Mild systemic reactions accounted for the majority of reported AEFI, and fatal SAEs were rare. This study also implied that passive surveillance might be an efficient safety monitoring system that can detect relatively rare AEFI.
Data Analysis of Upper Atmosphere Temperature Detected by Sounding Rockets in China

Field: Physics and Astronomy (Physical Sciences)

Abstract Sounding rockets launched by China have collected data on the upper atmosphere for nearly 50 years. In this work, the data accuracy and variable characteristics of upper atmosphere temperature data, gathered at heights of 20–60 km over Jiuquan, China, during 1974–2014, were analyzed. The relative accuracy of sounding rocket temperature data was determined by comparing the data with Mass Spectrometer and Incoherent Scatter (MSIS) model data by season, and with Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) from the Thermosphere, Ionosphere, Mesosphere Energetics and Dynamics ( TIMED ) satellite by year. The sounding rocket temperature data showed differences from MSIS in every season, with the minimum difference occurring in summer, the next smallest difference in winter, and the maximum difference occurring in autumn. The sounding rocket data showed smaller differences from the SABER data, although the deviation still fluctuated depending on the date and hour of the observations. In addition, the temperature distributions of the temperature profiles were examined at different times at the same heights. By linearly fitting the mean temperature profiles of each season, the statistical characteristics of the temperature changes with height were explored.
Serological and genetic characterization of Flavobacterium psychrophilum isolated from farmed salmonids in Turkey

Field: Veterinary (Health Sciences)

Abstract Turkey was the largest rainbow trout producer of the European countries in 2016, and the reason for this production is mainly attributed to its egg and fry production. Flavobacterium psychrophilum cause the highest rates of mortality in the starting to feeding stages of the fish. In the present study, twenty‐five F. psychrophilum isolates recovered from rainbow trout, coruh trout and brook trout were analysed by RAPD ‐ PCR , ERIC ‐ PCR , REP ‐ PCR and PCR ‐ RFLP , including 16S rRNA , gyr A and gyr B gene regions and PCR ‐based serotyping method. The PCR ‐based molecular analysis showed that the isolates could not be differentiated exactly according to isolation source and geographical region. Most isolates were of type‐1 and type‐2, and some of them were of type‐0 and type‐3; in addition, one isolate showed a unique serotype. The combined analysis results showed that F. psychrophilum isolates discriminated as five different genotypes and all isolates were successfully discriminated based on host.
A 13.56Mbps PSK receiver for 13.56MHz RFID applications

Field: Engineering (Physical Sciences)

This paper presents a receive chain for very-high bit rate (VHBR) communication over a short range 13.56MHz inductively coupled interface, using multi-bit-per-symbol phase-shift keying (PSK) as proposed for the ISO14443 VHBR amendment. A data rate of up to 13.56Mbps is achieved. The receiver consists of an analog front-end IC followed by an FPGA-based digital baseband processor (DSP). The analog front-end IC recovers the carrier from the antenna signal and performs PSK demodulation using an 8-bit time-to-digital converter (TDC). It consumes 100μA in the 13.56Mbps data rate mode. The FPGA-based DSP's main functions are symbol clock recovery in a closed-loop with the analog front-end as well as adaptive equalization. Target bit error rates of below 2·10 -4 were achieved for transmitted field strengths above 1.2A/m.
Pathways of NHEJ at Dysfunctional Telomeres and Their Resolution

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Shelterin is a multiprotein complex that prevents DNA damage signaling at chromosome ends. In its absence, DNA repair pathways are activated that can promote the fusion of dysfunctional telomeres resulting in chromosomal instability. The work presented here aims to understand how telomeres are protected from these pathogenic repair pathways. The first part of this thesis is focused on the DNA damage response factor 53BP1, a key regulator in double strand break (DSB) repair pathways in mammalian cells. By influencing key regulatory events at and near DNA ends, 53BP1 plays an important role in the decision between non-homologous endjoining (NHEJ) and homologous recombination (HR). Telomeres lacking the shelterin protein TRF2 have proven a versatile system for studying 53BP1 in DSB repair since 53BP1 protects dysfunctional telomeres from resection and promotes their mobility. Analysis of separation of function mutants of 53BP1 has identified the domain that is responsible for promoting the mobility of DSBs. Cells expressing 53BP1ΔMOB showed reduced levels of NHEJ at dysfunctional telomeres and damage foci roamed a smaller part of the nucleus. But which 53BP1 interacting factors are responsible for mediating the increased mobility remains unclear. The second part of this thesis aims to elucidate the DNA repair pathways that are activated when the shelterin component TRF1 is absent. The results provide tantalizing evidence that sister telomeres can fuse via the alternative-NHEJ (a-NHEJ) pathway when replication forks reach the end of the chromosome in cells that are deficient in TRF1. To prevent chromosome instability, mammalian cells appear to employ the Holliday Junction resolvase Gen1, which is capable of cleaving cruciform DNA structures that can be formed when telomeres fuse. The deletion of Gen1 from TRF1 null cells resulted in the accumulation of chromatin bridges and isochromosomes, indicative of genomic instability. The results presented here are of relevance to studies of human cancer cells since the presence of critically short telomeres induces sister telomere fusions via a-NHEJ. It is possible that replication stress underlies these fusion events and that Gen1 has evolved as a mechanism to counteract the consequences of chromosomal fusion events at telomeres.
STUDY OF FUNGI FOUND IN THE SOIL OF POTATO PLANTATION AREAS

Field: Agricultural and Biological Sciences (Life Sciences)

The Rhizosphere soil and non-rhizosphcre soil mycoflora of potato plantation field in Imphal East area were carried out by using dilution plate method for one crop season. Non-infected rhizosphere and rhizosphere soil mycroflora analysis revealed 10 fungal species. Out of which 2 belongs to Zygomycotina and 8 belongs to Deuteromycotina. The maximum number of fungal species were contributed by deuteromycotina. Fusarium salanishowed highest population in non-rhizosphere soil whereas Alternaria solarn dominated the fungal population in the rhizosphere soil. The maximum concentration of fungal population was recorded in the month of February. The lowest fungal population was recorded in the month of November both in non- rhizosphere and rhizosphere soil. The maximum number of soil microbial population was recorded in the diseased rhizosphere soil whereas the least population was found in non-rhizosphere soil. Key Words:Rhizosphere soil, Zygomycotina, Deuteromycotina Policy
Comparison of intercanine width in between Angle class II division 1 and division 2 malocclusions

Field: Dentistry (Health Sciences)

Introduction: Dental arch width measurement is needed to determine diagnoses and orthodontic treatment planning of Angle Class II Division 1 and Class II Division 2 malocclusions that have narrow maxillary dental arch generally. Dental arch width in this study was measured by maxillary and mandibular intercanine width. This study aimed to compare the differences of intercanine width between Angle Class II division 1 and Class II division 2 malocclusions. Methods: Descriptive comparative research with total samples of 67 study models, consisted of 34 Class II division 1 cases and 33 Class II division 2 cases. The minimum age of the samples chosen was 13 years old with no history of orthodontic treatment. A non probability consecutive sampling technique was used. Results: Study results showed the avarage maxillary and mandibular intercanine width of Class II Division 1 were 33,99 mm and 26,33 mm. Average maxillary and mandibular intercanine width of Class II Division 2 were 34,77 mm and 25,37 mm. Conclusions: T-test analysis showed no statistical significant differences in the intercanine width between Angle Class II Division 1 and Class II Division 2 malocclusions.
Evidence-based grounds of the efficacy of simvastatin (zocor): 15 years later

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The review describes the history of hypolipidemic therapy with statins. It gives the results of studies of the primary prevention of atherosclerosis and the treatment of hyperlipidemias with lovastatin, pravastatin, and fluvastatin. Emphasis is laid on trial data on the efficacy, tolerability, and safety of simvastatin (zocor). The results of studies, including regression ones, of this drug in different doses, controlled by biochemical, clinical, magnet resonance imaging, and ultrasonic data are summarized. There is a significant reduction in the risk of cardiovascular, coronary, and overall deaths and in that of stroke. There is evidence for the successful use of simvastatin (zocor) in combined therapy with fibrates, nicotinic acid, and ezetrol.
Intratumoral Injection of H101 in Combination With Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer

Field: Medicine (Health Sciences)

Abstract Background To evaluate the clinical benefit of concurrent chemoradiotherapy in combination with H101 injection for the treatment of locally advanced cervical cancer (LACC) patients. Methods The patients, all diagnosed with stage IIB or III cervical cancer according to The International Federation of Gynecology and Obstetrics (FIGO) stage (2009) with tumor length ≥6cm were enrolled at Zhejiang Cancer Hospital from July 2015 to April 2017. All patients received concurrent chemoradiotherapy (CCRT) in combination with intratumoral H101 injection before and during external beam radiotherapy (EBRT). The parameters recorded and analyzed included progression-free survival (PFS), overall survival (OS), tumor regression after EBRT and side effects, which were compared to another group of patients with similar characteristics treated with CCRT alone. Results Twenty patients were treated with CCRT in combination with intratumoral H101 injection and another group of 20 patients treated with CCRT alone was selected as control. The median follow-up time was 38 months (range 10-58 months). The 3-year local, regional, and overall PFS rates were 95% vs 66.6%( p = 0.02), 95% vs 62.5%(p = 0.029), and 65% vs 43.8%( p = 0.19), for H101 group and control group respectively. The 3-year (OS) was 74.3% vs 54.5%( p = 0.098), respectively. The median reduction of tumor length and volume for H101 group and control group were 37.7% vs 28.7%(p = 0.016) and 75.1% vs 62.4%(p = 0.001), respectively. The major adverse event related to H101 was fever. Conclusion CCRT in combination with intratumoral H101 injection is effective in treating LACC, and has an acceptable safety profile. Trial registration The study was registered at Chinese Clinical Trail Registry (ChiCTR-OPC-15006142).
Public Control in Municipalities of Constituent Entitties of the Russian Federation of the Siberian Federal District

Field: Social Sciences (Social Sciences)

Development of public control as an independent institution carried out in municipalities constitutes a part of the ideology according to which democratic states proceed their development. The purpose of the study is to identify problems that hinder the development of subjects of public control in municipalities. The object of this study covers public relations related to public control in municipalities; the subject of the study includes quantitative and qualitative characteristics of subjects of public control, legislation regulating their organization and activities. Methodologically, the paper is based on dialectical and system methods, methods of analysis and synthesis, as well as the formal legal method. The study showed that a) public control development in municipalities of the regions of the Siberian Federal District is carried out inconsistently; b) Federal Law No. 212‑FZ dated 21 July 2014 «On foundations of public control in the Russian Federation» sets forth foundations for the development of public control, but it does not provoke the expected activity in the use of its norms; c) among the reasons hindering the development of the legal institution under consideration, the author names insufficient informing of the population about the possibilities, legal grounds, forms of work, the procedure for creation, the best experience of the subjects of public control, Organizational issues include the lack of systematic posting of the necessary information about the activities of subjects of public control on the websites of municipalities and incorrect application of the norms of Federal Law No. 212‑FZ. Legal problems of the current legal regulation are caused by the lack of necessary legal regulation of the sphere under consideration).
Points from Letters: Phenothiazine(s)

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

BRTSw=Hcomings of others-presumably they hope their own virtues will show up better by contrast; but, really, 800 purple hearts a day are too much for any of us to swallow, literally or figuratively.No details have been given, so far as I know, of how many were in the family or how long the tablets were supposed to last, or whether the circum- stances justified the prescribing of purple hearts in any quantity.This statement has been so damaging to the profession in lay eyes and so surprising and shocking to the vast majority of doctors in general practice who never prescribe more than two Drinamyl a day-and these with some diffidence-that the Ministry should justify the statement of the official by supply- ing details to the profession by way of Prescribers' Notes or in the B.M.7.
Requirements And Threat Models of Adversarial Attacks and Robustness of Chest X-ray classification

Field: Computer Science (Physical Sciences)

Vulnerability to adversarial attacks is a well-known weakness of Deep Neural Networks. While most of the studies focus on natural images with standardized benchmarks like ImageNet and CIFAR, little research has considered real world applications, in particular in the medical domain. Our research shows that, contrary to previous claims, robustness of chest x-ray classification is much harder to evaluate and leads to very different assessments based on the dataset, the architecture and robustness metric. We argue that previous studies did not take into account the peculiarity of medical diagnosis, like the co-occurrence of diseases, the disagreement of labellers (domain experts), the threat model of the attacks and the risk implications for each successful attack. In this paper, we discuss the methodological foundations, review the pitfalls and best practices, and suggest new methodological considerations for evaluating the robustness of chest xray classification models. Our evaluation on 3 datasets, 7 models, and 18 diseases is the largest evaluation of robustness of chest x-ray classification models. We believe our findings will provide reliable guidelines for realistic evaluation and improvement of the robustness of machine learning models for medical diagnosis.
Sentence of the Court: Order and Problems of the Decision (Continuation)

Field: Social Sciences (Social Sciences)

The features, order and problems of sentencing are considered. The verdict of the court is the final decision in the criminal case. Particular attention in the article is paid to the order of the decision and pronouncement of the sentence and the legal status of the judge. An important problem of criminal proceedings in relation to the issuance of a reasonable and fair judgment is the imperfection of the legislation.
A simulation of growth duration in FACE rice

Field: Agricultural and Biological Sciences (Life Sciences)

Global atmospheric CO2 concentration([CO2]) was projected to reach levels of 650-780 μmol mol-1 at the end of this century(IPCC,2000).The increasing atmospheric [CO2] and associated climate may greatly affect agricultural productivity worldwide.However,little was known about the effect of free-air CO2 enrichment(FACE) on growth duration of rice.In order to predict the changes of growth duration of under FACE condition,we conducted a FACE experiment at Anzhen(31°37′N,120°28′E),Wuxi,Jiangsu province,in 2001-2003.The FACE facility consisted of three FACE rings(three repetitions) and five ambient rings,and the ambient rings were 90m apart to avoid contamination of elevated CO2.Rice were grown from transplanting to harvest under two levels of [CO2] for three consecutive years(2001-2003),and the target [CO2] of the FACE rings was 200μmol mol-1 above that in the ambient air.The annual mean temperature was about 16℃,the annual mean rainfall was 1150 mm and the annual sunshine hours were 2000h in the experiment area.The experiment was conducted in 3 years using the japonica cultivar Wuxiangjing 14.Seeds were sowed on 18 May and seedlings were hand transplanted with 3 plants each hill on 13 June.Hills and rows were 16.7 and 30 cm apart,respectively(equivalent to 24 hill m-2).Three levels of N application were: 150kg/hm2(low,LN),250kg/hm2(medium,MN) and 350kg/hm2(high,HN).To calculate the days of main growth duration of in both ambient and FACE plots,10 hills per experiment plot were selected and marked to investigate leaf age.Results showed that: the mean days from sowing to heading,from heading to maturity and the whole growth duration of shortened 3-4.5d(mean value 3.4d),2-3d(mean value 2.4d) and 5-7.5d(mean value 5.8d) in FACE treatment compared with CK.Increasing of nitrogen application rate could weaken the effect of FACE on growth duration.In order to describe these changes and predict the growth duration of rice,we developed a growth duration model of in FACE condition based on the rice clock model.The factor of N contents in plants was introduced to adjust the growth duration model in FACE rice.The model was tested with different experimental data and the errors between simulated days and observed days in the CK and FACE conditions were small,with the RMSE in different growth duration from the biggest 2.64d to the smallest 0.15d.The results showed that the growth duration model in FACE was not only accurate but also applicable.
Pengaruh Digital Payment (Brimo) Terhadap Kepuasan Keuangan Pada Umkm Di Kabupaten Bangkalan

Field: Business, Management and Accounting (Social Sciences)

Financial transactions using technology are developing in Indonesia, one of which is digital payments. Bangkalan Regency is experiencing significant changes in MSME payment and financial patterns in line with the adoption of digital payment technology. Therefore, it is important to understand the specific impact on MSMEs in the area. This research aims to determine the effect of digital payments on financial satisfaction among MSMEs in Bangkalan district, especially in terms of financial satisfaction. This research uses quantitative methods by collecting data using questionnaires and interview techniques. The research subjects were MSMEs in Bangkalan Regency and samples were taken using random sampling technique. The research results confirm that the adoption of digital payments has a significant positive impact on the level of financial satisfaction of Micro, Small and Medium Enterprises (MSMEs) in Bangkalan Regency. This finding is supported by the results of a simple linear regression test analysis, where the significance value (Sig) is 0.000, much smaller than the significance level Î± = 0.005 (5%). The research hypothesis (H1) which states that "digital payments have an effect on financial satisfaction" was successfully verified, showing that the higher the level of use of digital payments by MSMEs, the higher the level of financial satisfaction they feel.