jimnoneill/paper-to-field-training huggingface dataset:
MANAGEMENT OF COMPETITIVENESS OF AGRICULTURAL PRODUCTION IN THE CONTEXT OF FINANCIAL ECONOMIC DEVELOPMENT OF UKRAINE

Field: Economics, Econometrics and Finance (Social Sciences)

It is conducted an analytical estimation of theoretical and methodical principles for determining the competitiveness of agricultural products in this article; it is specified the system of indicators for the assessment of the competitiveness of products; it is determined the indicators that used for controlling the competitiveness of products; it is researched the dynamics of gross domestic product and agricultural production for 2012-2018; it is analyzed the influence of volumes of production of agricultural products on the dynamics of gross domestic product in both the short-term and long-term periods; a correlation field was developed for analyzing the relationship between the agricultural production index and economic growth in the long-term period for 2009-2017; it was established that an increase in the index of agricultural production by 1% will lead to an increase in GDP by 0,18%; The market of poultry production is researched, as one of the key components of agricultural production; it is determined the balance between demand and supply of Ukrainian poultry market, as well as the dynamics of its consumption for 2012-2017; it is calculated the concentration indexes on the market of poultry meat in Ukraine, that made it possible to identify the investigated market as oligopolistic; it is generalized a method of analysis of competitiveness taking into account peculiarities of poultry production; it is grounded the main directions of increasing competitiveness of poultry production in the context of financial and economic development of the industry and economy of Ukraine as a whole; it is revealed that increasing the competitiveness of Ukrainian poultry production should take place due to the growth of its quality; it is generalized indicators of the quality of poultry production; it is proposed the indicator of complex assessment of the quality of poultry products, which allows to account, to make analysis and control of costs to ensure its quality, which will enable to increase the competitiveness of the industry, which in turn will lead to financial and economic growth of the Ukrainian economy.
My innovation in cellular & molecular medicine

Field: Medicine (Health Sciences)

Liver is affected by any injuries, infections, metabolic disorders or depress by any reason then the digestion of vitamins, A, D, C, K, Iron and any other substance not digest properly and not absorb properly.But person will not get any problem and if long time he or she not gets any sign and symptoms then they not go for treatment.Many people gets problems but they ignore it and many times Doctors also do not know the real cause of problems.Many times we can see the problems in children but not in mothers and fathers.If any person gets some problem then we are trying to solve the problems by substitutes and by substitute the problems will be disappear for some time but not cure and after some time it will be relapse.
A Comparative Anatomic Study on Seven Leaves of Species of Domestic Mniaceae

Field: Agricultural and Biological Sciences (Life Sciences)

The author have studied the transsections of the leaves from seven species of Mniaceae: Trachycystis microphylla (Doz et Molk)Lindb, Mnium laevinerve Card, M thomsonii Schimp, Plagiomnium ellipticum (Brid)Kop, P rostratum (Schrad)Kop, P medium (B S G)Kop, P cuspidatum (Hedw) Kop.The results show that the morphological structure of the conductive strand and the stereid band in the costa,the differentiated margins of the leaves differ distinctly in different genus and species,and it can be used as the characters to classify the geus and species.In different geus,these characters are different obviously,so this paper just agrees with Koponen's opinions on the three genus.
Learning to Take Scripture Seriously

Field: Arts and Humanities (Social Sciences)

Abstract This paper is mainly the product of an international conference on sexuality and scripture that was held in Limuru, Kenya, during the summer of 2013. For almost two-thousand years, Christians have held different views on the role and authority of scripture in the Church. Those differences were made manifest by the participants in this conference. Largely because of their diverse cultural backgrounds, leaders from different parts of the global Christian community continue to use the Bible in the debates over human sexuality in remarkably different ways. This paper identifies the Contextual Bible Study method as a promising hermeneutical tool for finding agreement in the interpretation of scripture among individuals from such diverse backgrounds and from competing theological positions. After reviewing the Contextual Bible Study method and its applicability to the issue of human sexuality, the paper suggests the benefits of leaving behind familiar arguments over those passages of scripture most often cited in these debates in favour of a robust discussion of yet largely unexplored theological arguments.
Improving the treatment of coarse-grain electrostatics: CVCEL

Field: Computer Science (Physical Sciences)

We propose an analytic approach for calculating the electrostatic energy of proteins or protein complexes in aqueous solution. This method, termed CVCEL (Circular Variance Continuum ELectrostatics), is fitted to Poisson calculations and is able to reproduce the corresponding energies for different choices of solute dielectric constant. CVCEL thus treats both solute charge interactions and charge self-energies, and it can also deal with salt solutions. Electrostatic damping notably depends on the degree of solvent exposure of the charges, quantified here in terms of circular variance, a measure that reflects the vectorial distribution of the neighbors around a given center. CVCEL energies can be calculated rapidly and have simple analytical derivatives. This approach avoids the need for calculating effective atomic volumes or Born radii. After describing how the method was developed, we present test results for coarse-grain proteins of different shapes and sizes, using different internal dielectric constants and different salt concentrations and also compare the results with those from simple distance-dependent models. We also show that the CVCEL approach can be used successfully to calculate the changes in electrostatic energy associated with changes in protein conformation or with protein-protein binding.
A Retrospective Analysis of Provider-to-Patient Secure Messages: How Much Are They Increasing, Who Is Doing the Work, and Is the Work Happening After Hours? (Preprint)

Field: Health Professions (Health Sciences)

BACKGROUND

Patient portal registration and the use of secure messaging are increasing. However, little is known about how the work of responding to and initiating patient messages is distributed among care team members and how these messages may affect work after hours.

OBJECTIVE

This study aimed to examine the growth of secure messages and determine how the work of provider responses to patient-initiated secure messages and provider-initiated secure messages is distributed across care teams and across work and after-work hours.

METHODS

We collected secure messages sent from providers from January 1, 2013, to March 15, 2018, at Mayo Clinic, Rochester, Minnesota, both in response to patient secure messages and provider-initiated secure messages. We examined counts of messages over time, how the work of responding to messages and initiating messages was distributed among health care workers, messages sent per provider, messages per unique patient, and when the work was completed (proportion of messages sent after standard work hours).

RESULTS

Portal registration for patients having clinic visits increased from 33% to 62%, and increasingly more patients and providers were engaged in messaging. Provider message responses to individual patients increased significantly in both primary care and specialty practices. Message responses per specialty physician provider increased from 15 responses per provider per year to 53 responses per provider per year from 2013 to 2018, resulting in a 253% increase. Primary care physician message responses increased from 153 per provider per year to 322 from 2013 to 2018, resulting in a 110% increase. Physicians, nurse practitioners, physician assistants, and registered nurses, all contributed to the substantial increases in the number of messages sent.

CONCLUSIONS

Provider-sent secure messages at a large health care institution have increased substantially since implementation of secure messaging between patients and providers. The effort of responding to and initiating messages to patients was distributed across multiple provider categories. The percentage of message responses occurring after hours showed little substantial change over time compared with the overall increase in message volume.
A Pressure Based Multigrid Procedure for the Navier-Stokes Equations on Unstructured Grids

Field: Mathematics (Physical Sciences)

We present details and performance of a pressure based multigrid solution procedure for the Navier-Stokes equations discretized on triangular grids. The discretization uses a control volume methodology, with linear inter-nodal variation of the flow variables. The use of the multigrid technique provides rapid and grid-independent rates of convergence. Three model driven cavity flows are computed, and the performance of the method at several grid densities and Reynolds numbers is reported. Representative flow fields characterizing the viscous eddies are also presented. 1. INTRODUCTION The multigrid technique [1] provides an efficient means of smoothing high and low frequency errors that arise during the iterative solution of elliptic equations. Multigrid acceleration of solution procedures on unstructured meshes has been demonstrated earlier for single elliptic equations [2,3], for Euler equations [4-7], and for the compressible Navier-Stokes equations [8]. These procedures have used com...
A novel anti-melanoma SRC-family kinase inhibitor

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

The major drawback of melanoma therapy with BRAF and MAPK inhibitors is the innate and acquired drug resistance. We therefore explored alternative targets and developed a new compound, SAB298, that is a SRC-family kinase (SFK) inhibitor. The drug is cytotoxic to patient-derived melanoma cells regardless of oncogene expression and inhibits tumor growth in vivo. As expected, it inhibited SRC and PI3K activity, and had the additional property of ERBB2 inhibition, that lead to inactivation of the two ERK phosphatases PP2A and SHP2. In 57% of the melanoma cell lines tested, the consequent increase in ERK activity lead to proteolytic degradation of its substrate, the lineage specific transcription factor MITF, likely contributing to growth arrest. Treatment with a combination of SAB298 and AZD6244 (selumetinib), induced a synergistic growth inhibition, suggesting that the new compound could be used in the clinic as a substitute for, or in combination with MAPK inhibitors.
Dietary food antioxidants and their radical scavenging activity: A review

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Food antioxidants can prevent or/and delay free radical formation which is responsible for oxidative stress. Nowadays, natural remedy is the highest concern in many countries, as well as discouraging the intake of synthetic counterparts to avoid the burden of side effects on human health. Regular intake of dietary antioxidants could help to improve the fitness of the body, and subsequently make the body more competitive in its fight against diseases through enhanced immune response. The present review thus summarised recent knowledge on the dietary source of antioxidants, and also mechanism of action and functionalities on human health benefits. Due to the proven ability to restore mitochondrial function and cellular redox balance, food antioxidants also have great potential as natural therapies against COVID-19. However, the numbers of trials are still limited. There must be more tests with the hope that these compounds will mitigate the COVID-19 and similar outbreaks in the future.
P128 Accuracy of the combination of transabdominal and transperineal ultrasound for the evaluation of Ulcerative Colitis activity

Field: Medicine (Health Sciences)

Abstract Background Transabdominal Bowel Ultrasound (TBUS) is useful technique to assess disease activity and extent in patients with ulcerative colitis (UC); however, the evaluation of the rectum by TBUS is difficult. Recently, transperineal ultrasound (TPUS) has been proposed as a useful diagnostic tool in the evaluation of rectal disease. The aim of the study is to to assess the concordance between the combination of TPUS/TBUS and endoscopy in adult patients with UC. Methods Fifteen consecutive adult patients with UC were prospectively enrolled from June to November 2021. Disease activity was determined using Partial Mayo Score (PMS) and Mayo Endoscopic Subscore (MES). TBUS and TPUS were performed within a week from endoscopy. MES ≤ 1, bowel wall thickness ≤ 3mm in the colon and ≤ 4mm in the rectum were defined as remission. A concordance analysis comparing endoscopy and US was performed by kappa statistics Results Ten patients were male (66%) and 8 female (34%), with a median age of 39± 13,9. Two patients had a pancolitis, 6 a distal colitis, and 3 a proctitis. 4 patients were in remission. The agreement between endoscopy and rectal evaluation with TBUS was fair (k =0.40), while the agreement with TPUS was excellent (k =0.86). The evaluation of the colon with TBUS showed good concordance in the right colon (k= 0.63), left colon (k=0.65), and sigmoid colon (k=0.72), and excellent agreement in the transverse colon (k= 1). Conclusion These preliminary data showed that the combination of TBUS and TPUS allows to easily and accurately study all the segments of the large intestine in patients with UC, overcoming the limitation related to the reduced accessibility to the rectum with only trans abdominal approach.
Expression of Rice Grassy Stunt Virus in Rice Protoplasts

Field: Agricultural and Biological Sciences (Life Sciences)

With the rice protoplast infection system, the purified virus particles of Rice grassy stunt virus were delivered into rice protoplasts derived from suspension cells of rice cultivars Tainong 67 via PLO-mediated method. Using antisera prepared against the purified virus particles of RGSV, NS3 fusion protein and purified NS6 protein, expressison profiles of RGSV and its encoded proteins in rice protoplasts were investigated by indirect ELISA and Western blot. The results showed as follows: RGSV was detectable in rice protoplasts 24 h after inoculation, and reached its highest level 36 h after inoculation. NS6 was detected 15 h after inoculation, and reached its highest level 30 h after inoculation.
Valiolamine, a new .ALPHA.-glucosidase inhibiting aminocyclitol produced by Streptomyces hygroscopicus.

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Valiolamine, a new aminocyclitol has been isolated from the fermentation broth of Streptomyces hygroscopicus subsp. limoneus and its structure has been determined to be (1(OH),2,4,5/1,3)-5-amino-1-C-(hydroxymethyl)-1,2,3,4-cyclohexanetetr ol. Valiolamine has more potent alpha-glucosidase inhibitory activity against porcine intestinal sucrase, maltase and isomaltase than valienamine, validamine and hydroxyvalidamine which were reported as building blocks of validamycins and microbial oligosaccharide alpha-glucosidase inhibitors. In addition, valienamine, validamine and hydroxyvalidamine have been isolated from the fermentation broth.
Experiment on cutting propagation of Rhododendron rivulare

Field: Agricultural and Biological Sciences (Life Sciences)

Effects experiment of cutting propagation of Rhododendron rivulare were studied with different root-inducing regulator and cutting time.The results showed that R.rivulare began to root 60 d later after cutting.The rooting rates were significant difference among different root-inducing regulator and cutting time.Taking indolebutyric acid as root-inducing regulator with concentration of 150 mg/L,the average rooting rate was 55% as cutting in October and 82% in July,and the highest rooting rate in July was 85%.Taking ABT as root-inducing regulator with concentration of 100 mg/L,the average rooting rate was 67% and the highest survival rate was 70%.Taking α-Naphthylacetic acid as root-inducing regulator with concentration of 100 mg/L,the average rooting rate was 58% and the highest rooting rate was 65%;
Development of a Spontaneous Heating / Fire Risk Index for Opencast Coal Mines

Field: Earth and Planetary Sciences (Physical Sciences)

Presently, researchers and coal industries in all over world are recognizing the consequence of spontaneous heating/fire of coal for sustainability of natural resources and environmental problems. The awareness among coal producing countries needs a well focused research in spontaneous heating/fire risk analysis and its management for the public’s concerns safety of miners, equipment and life of mines. An attempt has been made to develop spontaneous heating/fire risk index (SHFRI) for opencast mines to assess spontaneous heating/fire risk. The SHFRI of an opencast mine determines based on relative susceptibility potential to spontaneous heating on four major parameters such as coal characteristics, geological conditions, mining methods and environmental parameters, which evaluates the overall risk index of opencast mines. The SHFRI was subdivided in to five levels (I-V) as: very safe, safe, medium risk, high risk and extremely high risk. The model is tested with the field data collected as well as laboratory data from two different opencast mines for its suitability. This index is still at an elementary level of design and further development of the SHFRI will undoubtedly enhance the features and reliability of the index.
GUIDANCE DOCUMENT Field Demonstration, Optimization, and Rigorous Validation of Peroxygen-Based ISCO for the Remediation of Contaminated Groundwater- CHP Stabilization Protocol

Field: Environmental Science (Physical Sciences)

Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information, including suggestions for reducing this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to a penalty for failing to comply with a collection of information if it does not display a currently valid OMB control number.
Comparing the sterility and visibility of surgical marking pens available in Australia

Field: Medicine (Health Sciences)

Background Surgical site marking is an important safety procedure prior to surgery. Visibility of pen marks is affected by surgical wash which increases the risk of wrong‐site surgery. Additionally, multiple patient contact with a single pen is a potential source of bacterial transmission. In this study we compare pens commonly used for surgical marking in Australia. Methods We conducted an unblinded, prospective cohort study comparing 12 marking pens. Six volunteers' thighs were marked with each pen. Standardized photographs were taken before and after wash with four prep solutions. Ink visibility was analysed using grayscale images, comparing the pen mark tone before and after wash. The pen tips were swabbed for culture. Results Red tinted 2% chlorhexidine gluconate (w/v) with 70% isopropyl alcohol (v/v) was shown to reduce pen mark visibility significantly more than the other solutions used. The Pentel N50 permanent marker and Aspen WriteSite Plus were least affected by wash. No pen tip cultured any bacteria. Conclusions When marking the correct site for surgery, we recommend the use of either the Pentel N50 permanent marker or Aspen Writesite Plus pen. A 2‐min interval between patient contact limits bacterial transmission.
Adhesive, Stretchable, and Spatiotemporal Delivery Fibrous Hydrogels Harness Endogenous Neural Stem/Progenitor Cells for Spinal Cord Injury Repair

Field: Medicine (Health Sciences)

Aligned fibrous hydrogels capable of recruiting endogenous neural stem/progenitor cells (NSPCs) show great promise in spinal cord injury (SCI) repair. However, the hydrogels suffer from severe issues in close contact with the transected nerve stumps and harnessing the NSPC fate in the lesion microenvironment. Herein, we report aligned collagen-fibrin (Col-FB) fibrous hydrogels with stretchable property, adhesive behavior, and stromal cell-derived factor-1α (SDF1α)/paclitaxel (PTX) spatiotemporal delivery capability. The resultant Col-FB fibrous hydrogels exhibited 1.98 times longer elongation at break (230%), 2.55 times lower Young's modulus (17.93 ± 1.16 KPa), and 2.21 times greater adhesive strength (3.45 ± 0.48 KPa) than collagen (Col) fibrous hydrogels. The soft aligned fibrous hydrogels simulate the oriented microstructure and soft tissue feature of a natural spinal cord and provide elasticity and adhesivity to ensure a persistent close contact with host stumps. The repair of complete transection SCI in rats demonstrates that "middle-to-bilateral" SDF1α gradient release induced endogenous NSPC migration to the lesion site in 10 days, and SDF1α/PTX sequential release promoted neuronal differentiation of the recruited NSPCs over 8 weeks, leading to hind limb locomotion recovery. The presented strategy was proved to be efficient for harnessing endogenous NSPCs, which facilitate SCI repair significantly.
An unusual case of painful ophthalmoplegia in a patient with rheumatoid arthritis.

Field: Medicine (Health Sciences)

A 43-year-old woman with long-standing rheumatoid arthritis and systemic lupus erythematosus had pain and horizontal diplopia. Clinical symptoms were consistent with inflammation of the right superior oblique tendon sheath, but a computed tomographic scan showed no pathology. Treatment with systemic corticosteroids reduced the symptoms, but the patient was left with a persistent muscle imbalance.