jimnoneill/paper-to-field-training huggingface dataset:
Tapetal Effect of an Azalide Antibiotic Following Oral Administration in Beagle Dogs

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Journal Article Tapetal Effect of an Azalide Antibiotic Following Oral Administration in Beagle Dogs Get access J. H. FORTNER, J. H. FORTNER Drug Safety Evaluation, Pfizer IncGroton, Connecticut 06340 Search for other works by this author on: Oxford Academic PubMed Google Scholar W. B. MILLISEN, W. B. MILLISEN Drug Safety Evaluation, Pfizer IncGroton, Connecticut 06340 Search for other works by this author on: Oxford Academic PubMed Google Scholar G. R. LUNDEEN, G. R. LUNDEEN Drug Safety Evaluation, Pfizer IncGroton, Connecticut 06340 Search for other works by this author on: Oxford Academic PubMed Google Scholar A. B. JAKOWSKI, A. B. JAKOWSKI Drug Safety Evaluation, Pfizer IncGroton, Connecticut 06340 Search for other works by this author on: Oxford Academic PubMed Google Scholar P. M. MARSH P. M. MARSH Drug Safety Evaluation, Pfizer IncGroton, Connecticut 06340 Search for other works by this author on: Oxford Academic PubMed Google Scholar Toxicological Sciences, Volume 21, Issue 2, August 1993, Pages 164–173, https://doi.org/10.1093/toxsci/21.2.164 Published: 01 August 1993 Article history Received: 30 December 1992 Accepted: 23 April 1993 Published: 01 August 1993
SSC-3 Revision 04a Letter Ballot Comment Database (08-095r2) Company number tech/edit Page Sec/table/fig locator Comment Proposed Solution Resolution Status

Field: Computer Science (Physical Sciences)

Verifying the key wrapper’s signature allows a device server that supports public key cryptography for key wrapping to ensure the authenticity of the IBM 76 T 86 Comment = may ensure s/b ensures wrapped key. SYM-001 T xviii Foreword In the second paragraph, the name of This standard specifies the A the field and the structure containing it are incorrect, and the reference should be to the published SAM-3. external behavior of a device server that defines itself as a sequential-access device in the PERIPHERAL DEVICE TYPE field of the standard INQUIRY data. This device type is known as a stream device. This standard conforms to ANSI INCITS 402-
Planar Rectangular Microstrip Patch Antenna Array with Corporate-Feed Network for Gain Enhancement

Field: Engineering (Physical Sciences)

Abstract: The design and performance analysis of a inset-fed planar rectangular microstrip patch antenna array with corporatefeed network systems is presented in this paper. This design aims to increase the gain of the rectangular patch antenna through the use of a 16-element planar rectangular antenna array. Each element in this planar array is fed by T-junction power divider networks with quarter-wave transformer lines via the corporate-feed method. The antenna is designed over the operating frequency of 2.4 GHz using the substrate material FR-4, which has a dielectric constant of 4.4 and a loss tangent of 0.002. By the addition of radiating patches in the array design, the gain, directivity and bandwidth also has been improved significantly. The proposed antenna array provides a gain of 9.284 dB, a directivity of 16.2 dBi, and a bandwidth of 0.361 GHz. The designed antenna can be used for wireless applications.
The Future of Leasing in the UK

Field: Economics, Econometrics and Finance (Social Sciences)

The future of leasing and its role in the economy are difficult to assess with precision in the wake of the 1984 Finance Act. The changes in the rates of capital allowances and Corporation Tax announced in the 1984 Budget have undoubtedly had an unprecedented impact in stimulating the growth of leasing in the UK in the transitional period, but the removal of most of the tax advantage at the end of March 1986 is likely to precipitate a contraction in leasing activity in the short term. The position in the longer term is somewhat indeterminate and will largely be dependent upon the way in which the market adapts both in terms of supply and demand to the changes in the tax structure.
Changes of Calpain-10 Gene Transcription in Bone Marrow Stem Cells Treated by Serum Deprivation in Rats

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Objective To determine whether serum deprivation can induce apoptosis of bone marrow stem cells (BMSCs) in rats,and explore whether Calpain-10 involved in the apoptosis of BMSCs.Methods Primary cultured rat BMSCs were incubated.Cells phenotype was identified by flow cytometry. Apoptotic cells were counted by flow cytometry following PI/Annexin-V staining. Fluorescence quantitation polymerase chain reation(PCR) was used to detect Calpain-10 mRNA levels in BMSCs at 24 h after serum deprivation.Result Cell phenotype identification showed positive antigen expressions with CD29,CD44,CD105 and negative antigen expressions with CD45,CD14,CD34; Apoptotic BMSCs of early stage took up the highest proportion of the whole cells at the time point of 24 h after serum deprivation compared with the other 2 time points, 0 h and 48 h. Compared with normal control ,the mRNA levels of Calpain-10 in BMSCs exposed to serum deprivation for 24 h significantly increased(2-ΔΔCT=22.433).Conclusion Serum deprivation can induce apoptosis of BMSCs, and Calpain-10 may be involved in the apoptosis of rat BMSCs.
Effects of Dietary Silymarin and Selenium-yeast on Energy Metabolism, Growth, Hematological Indices and Immune Status of Barbari Goat during Cold Stress

Field: Agricultural and Biological Sciences (Life Sciences)

Background: The aim of the present study was to assess the effects of silymarin (SM) and selenium-yeast (SY) on energy metabolism, growth, hematological indices and immune status of Barbari goat during cold stress. Methods: Thirty two Barbari goats (age: 6-8 months) were selected from ILFC- II, SVPUAT, Meerut (Uttar Pradesh) India. Experimental animals were randomly divided into four groups (n=8) according to body weight and age. First group (CON/C) was kept as control group giving only basal diet, second group (T1 /SM600) supplemented with 600 mg Silymarin/kg DM, third group (T2 /SeY) supplemented with 0.3 mg Selenium as Se-Yeast/kg DM and fourth group (T3 /SM600+SeY) supplemented with 600 mg Silymarin + 0.3 mg Selenium as Se-Yeast/kg DM along with basal diet for 90 days of the experimental periods. Result: Mean body weight gain (BWG) and dry matter intake (DMI) of the supplemented group was found significantly (P less than 0.01) more than control group where as feed conversion ratio (FCR) was lower (P less than 0.01) in the supplemented group. Plasma glucose concentration was found significantly (P less than 0.01) lower where as plasma concentration of NEFA had no effect in the supplemented group as compare to control group. Haemoglobin and total immunoglobulin level was found significantly (P less than 0.01) higher in supplemented group as compare to control. The results of this study indicated that supplementation of SM and SY have important role in improving growth performance, feed intake and immune status of Barbari goat during cold stress.
On Assessing Organizational Priorities: Concept and Method

Field: Social Sciences (Social Sciences)

Criticisms of the concept “organizational goal” are summarized. An alternative formulation is proposed wherein organizations are viewed as open systems. Through continual interaction incumbents seek to manipulate, and are manipulated by, expectations that they, and persons within various environmental sectors, hold for the organization regarding its mission, authority relations, relative status, affective expressions and sanctioning activity. Organizational missons include sets of social expectations which define appropriate tasks, priorities, territoralities, processing procedures and evaluation criteria. Behavioral observations of police communication officers are used to explore one aspect of mission—organizational priority. Three types of criteria appear critical in understanding priority rankings: 1) feedback intensity, 2) environmental capability to influence recognition and acceptance of feedback, and 3) sequential requirements.
Planning of motion trajectory and analysis of position and pose of robot based on rehabilitation training in early stage of stroke

Field: Engineering (Physical Sciences)

Rehabilitation robot is a certain robot used especially to rehabilitation training, whose main function is to help the patient with various recovery trainings with motor function. This thesis, according to requirements of rehabilitation training, builds analysis of motion pose and motion trajectory planning tactics of robot motion space based on rehabilitation training in early stage of stroke, makes position and pose analysis of rehabilitation-training robot, calculates out posture of the robot terminal controller, and finally puts forward rehabilitation training trajectory used in robot reappearance in light of experiment data.
TLR/BCR co-engagement induces mature and protective T-cell independent antibody responses through MyD88 and PI(3)K signalings

Field: Immunology and Microbiology (Life Sciences)

Abstract B cells are central to immune responses to infections and vaccines by producing high-affinity and class-switched protective antibodies, often in a T cell-dependent manner. Prompted by our findings that dual TLR/BCR engagement induces efficient CSR in vitro, to a high level comparable to that induced by CD40 engagement, here we have analyzed induction of T cell-independent CSR/SHM and antibody responses by TLR-BCR co-engagement. Immunization of wildtype C57 mice with NP hapten conjugated to TLR4-engaging LPS (NP-LPS), but not NP-Ficoll admixed with LPS, elicits high-affinity and class-switched IgGs (IgG1, IgG2a, IgG2b, IgG3), at levels comparable to those elicited by a T cell-dependent antigen NP-CGG. NP-LPS also induces sustained and high levels of IgG2a, IgG2b and IgG3, but not IgG1, in Tcrβ−/−Tcrδ−/− mice, which are devoid of T cells and, as expected, fail to mount any response to NP-CGG. Immunization of both wildtype and Tcrβ−/−Tcrδ−/− mice with highly purified Salmonella typhimurium (S. typhimurium) flagellin, which has dual BCR and TLR5 engaging activities, elicits flagellin-specific antibodies that can opsonize S. typhimurium. T cell-independent immune responses, which are impaired in mice lacking Myd88 or Pik3r1 in B cells, are associated with high mutation loads in VH genes, generation of switched B cells, and B cell differentiation into long-lived plasma cells and memory B cells, which can be re-activated for anamnestic antibody responses. Thus, SHM/CSR and B cell differentiation into plasma cells and memory B cells can occur independently of T cells, leading to protective mature antibody responses.
Cache architectures to improve IP lookups

Field: Computer Science (Physical Sciences)

IP address lookup is an important processing function of Internet routers. The challenge lies in finding the longest prefix that matches the packet’s destination address. One of the issues concerning IP address lookups is the average lookup time. In previous works, caching was shown to be an effective method to minimize the average lookup time. Caching involves storing information on recent IP lookup results in order to decrease average lookup times. In this thesis, we present two architectures that contain a prefix cache and a dynamic substride cache. The dynamic substride cache stores longest possible substrides from previous lookups, and is used in conjunction with a prefix cache. Successful hits in both the caches help reduce the number of worst-case lookups in the low level memory containing the IP routing table in a trie data structure. From simulations, we show that the two architectures show up to 99.9%global hit rate. Furthermore we present analytical models to find optimal designs for the two architectures. We also show that the architectures can support incremental updates once appropriate modifications are made to the trie data structure.
Fast optical switching in a high power Nd: YAG

Field: Physics and Astronomy (Physical Sciences)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Sandra Giacomini, Gianfranco Innocenti, Paolo Mataloni, and Francesco De Martini, "Fast optical switching in a high power Nd: YAG," Appl. Opt. 26, 3179-3181 (1987) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
LOW CYP2E1 GENE EXPRESSION PERMITS PHARMACOLOGICAL SELECTION OF TRANSPLANTED HUMAN HEPATOCYTES IN VIVO

Field: Medicine (Health Sciences)

To induce proliferation of transplanted human cells in immunocompetent rats by administration of hepatotoxic doses of a selection agent. GFP-Huh7, a hepatocytederived cell line with low CYP2E1 expression, was used. Expression of CYP2E1, an enzyme responsible for conversion of acetaminophen (APAP) into hepatotoxic compounds, was quantitated by real-time PCR. To prevent rejection, immunological tolerance was induced by introduction of GFP-Huh7 cells into fetal rats in utero, prior to development of the immune system. After birth, GFP-Huh7 cells were transplanted and treated with pharmacological doses of APAP. ALT levels and histology were to detect liver damage. GFP (+) cells in rat livers were detected by real-time PCR and fluorescence microscopy. Expression of CYP2E1 in GFP-Huh7 cells was only 4% compared to control cells. Animals treated with APAP increased ALT to 210 IU/ml on day 1, followed by resolution by day 3. Histology confirmed patchy necrosis corresponding in time to the ALT peak. Fluorescence microscopy of livers from transplanted, APAP treated rats showed an increase of GFP (+) cells/field from 4±2 on day 2 to 45±10 on day 7. Real-time PCR confirmed a 10-fold increase of GFP mRNA in APAP treated rats. Control animals had no significant changes of GFP (+) cells or mRNA levels. In vivo, the difference in CYP2E1 gene expression between GFP-Huh7 and host hepatocytes provides a convenient and efficient pharmacological selection resulting in enrichment of GFP-Huh7 cells. Down regulation of CYPs by siRNA may permit application of the selection to other liver cell lines.
Diversity of abyssal agglutinated foraminifera from Cenomanian to Santonian sediments of the North Atlantic

Field: Earth and Planetary Sciences (Physical Sciences)

Benthic foraminiferal assemblages of distinctive taxonomic composition occur at the top of benthic fossil-free black shales which correspond to the anoxic event at the Cenomanian/Turonian boundary in the North Atlantic abyssal DSDP/ODP sites 386, 398, 603 and 641. These assemblages consist of minute, thin-walled agglutinated foraminifera with low specific diversity of 2 to 4 species, variable abundance and dominance of few taxa (Haplophragmoides, Rhizammina and Glomospira). The species are inferred to be opportunistic, able to survive in low-oxygen environments and to be pioneers recolonizing the seafloor after cessation of bottom-water anoxia. Most species are characterized by test morphologies with high surface/volume ratios and single-layered wall structures, with loosely agglutinated grains, and small amounts of organic cement for agglutination. These features are best observed in material from ODP Hole 641A which has exceptional foraminiferai preservation because of its shallow burial depth. The successive appearance of benthic foraminifera after the anoxic event is probably controlled by the continuous reoccurrence of more oxygenated bottom- and interstitial-water conditions. With the final development of oxic bottom-water conditions in the Turonian, a rapid radiation of deep-water agglutinated foraminifera occurred in the North Atlantic.
Investigating Constraints: Law Enforcement against Women and Children Traffickers in Indonesia (Case Study: Lampung Province, Indonesia)

Field: Social Sciences (Social Sciences)

This paper is attempting to identify the constraints that law enforcement
agencies face to convict the traffickers of women and children trafficking
through criminal justice process. Using qualitative research methodology, case
study method and interview with key informants from law enforcement
agencies and NGO who handle women and children trafficking cases, this
study has concluded that not only weak legal mechanism and procedures, but
also poor capacity of law enforcement agencies in responding the cases,
corruption and reconciliation process between the traffickers and victims
become the constraints in bringing the traffickers of women and children into
justice.
Theorising news mediations of the Zuma rape trial – citizens and subjects in collision

Field: Social Sciences (Social Sciences)

One of the challenges to studying the media in non-‘Western’ locations is to decide on appropriate and relevant theoretical framings for such work. Moreover in African contexts there is a call for African scholarship. In this paper I propose that two very different sets of theories are relevant to theorising the media in a southern African context. First I draw on Foucauldian understandings of governmentality and subjectivities, in spite of the fact that Foucault and his commentators make frequent reference to the ‘Western’ world and the ‘Western subject’. In addition to Foucauldian insights, I also draw on African scholar, Mamdani's theories. He argues that colonial power was effected through indirect rule to constitute people as either ‘citizen’ or ‘subject’. The bifurcated nature of the state thus proposed different sets of identities and has resulted in a particular ‘history of the present’. From a position that argues that Foucault's and Mamdani's insights are fundamental to understanding this postcolonial context and the media constructions that result, I relate them empirically to a case study of the coverage and the accompanying popular responses in the South African press of the controversial rape trial of former South African deputy president, Jacob Zuma.1 1. This may be the case of the once and future king. At the time of reading these proofs (February 2009), Zuma is billed as the future president of South Africa after the April 2009 elections. If a rights-based discourse informed much of the reporting, it did this by constituting the discourse of ethnicity (rather than the customary) as other. At the same time both patriarchal and gender rights discourses were in unequal contestation.
Unveiling How Examples Shape Visualization Design Outcomes

Field: Computer Science (Physical Sciences)

Visualization designers (e.g., journalists or data analysts) often rely on examples to explore the space of possible designs, yet we have little insight into how examples shape data visualization design outcomes. While the effects of examples have been studied in other disciplines, such as web design or engineering, the results are not readily applicable to visualization due to inconsistencies in findings and challenges unique to visualization design. Towards bridging this gap, we conduct an exploratory experiment involving 32 data visualization designers focusing on the influence of five factors (timing, quantity, diversity, data topic similarity, and data schema similarity) on objectively measurable design outcomes (e.g., numbers of designs and idea transfers). Our quantitative analysis shows that when examples are introduced after initial brainstorming, designers curate examples with topics less similar to the dataset they are working on and produce more designs with a high variation in visualization components. Also, designers copy more ideas from examples with higher data schema similarities. Our qualitative analysis of participants' thought processes provides insights into why designers incorporate examples into their designs, revealing potential factors that have not been previously investigated. Finally, we discuss how our results inform how designers may use examples during design ideation as well as future research on quantifying designs and supporting example-based visualization design. All supplemental materials are available in our OSF repo.
Asymptotic Stability of Gaver’s Parallel System Attended by a Cold Standby Unit and a Repairman with Multiple Vacations

Field: Mathematics (Physical Sciences)

We investigate Gaver’s parallel system attended by a cold standby unit and a repairman with multiple vacations. By analysing the spectral distribution of the system operator and taking into account the irreducibility of the semigroup generated by the system operator we prove that the dynamic solution converges strongly to the steady state solution. Thus we obtain asymptotic stability of the dynamic solution of the system.
Pseudodifferential Operators on Stratified Manifolds

Field: Mathematics (Physical Sciences)

We consider a specific class of manifolds with singularities, namely, stratified manifolds, and describe a class of pseudodifferential operators (PsiDO) related to differential operators with degeneration of first-order with respect to the distance to the strata on such manifolds. (For manifolds with isolated singularities, this is a Fuchs type degeneration.) We restrict ourselves to the case of zero-order operators in L^2 spaces. The definition of PsiDO adopted in our approach uses induction over the number of strata in the manifold. The induction process naturally involves PsiDO with parameters.
Tendinopathies du sportif: étiologie, diagnostic et traitement [Tendinitis in athletes: etiology, diagnosis and treatment].

Field: Medicine (Health Sciences)

Tendinopathy is one of the most common diagnosis in sports. Knowledges about their etiology, the repair process to their diagnosis and their treatment have improved thanks to the development of imaging, especially ultra- sound. The disorder whose etiology could be mechanical or degenerative can cause long- term disability and sometimes the end of the sport carreer. The risk of reccurence is com- mon; this may lead to tendon rupture whose functional effects can be significative. The management should be early: it must respect the deadlines for tendon healing and pro- pose a gradual recovery efforts after elimina tion of the contributing factors involved.
Molecular data do not support the current division of Orthotrichum (Bryophyta) species with immersed stomata

Field: Agricultural and Biological Sciences (Life Sciences)

Abstract Genetic relationships between 27 Orthotrichum species of the subgenera Orthotrichum and Pulchella were reconstructed using the internal transcribed spacer regions 1 and 2, the chloroplast trnH‐psbA region, and intron–exon splice junction (ISJ) and inter‐simple sequence repeats (ISSR) markers. A phylogenetic analysis did not reflect the current division of the subgenus Pulchella into the sections Diaphana , Pulchella , and Rivularia . Species of the section Rivularia did not form a monophyletic group, and the only markers that indicated the distinctness of the section Pulchella were ISJ and ISSR. The most genetically diverse section was Diaphana , whose species were divided into several clades. The only proper phylogenetic unit was the subgenus Orthotrichum . The applied markers revealed the process of cryptic speciation in species of both subgenera.