jimnoneill/paper-to-field-training huggingface dataset:
Editorial Dying for attention: Microparticles and angiogenesis

Field: Medicine (Health Sciences)

See article by Brill et al. [18] (pages 30–38) in this issue. Microparticles, which were initially described as cell dust, have revealed over the past few years several exciting and unexpected properties. Microparticles are submicron vesicles shed from plasma membranes following cell activation or apoptosis, whose protein and lipid profile may be considered as a snapshot of the phenotype of the cell they stem from. The molecular mechanisms of microparticle formation and shedding are not yet fully understood, but seem to involve the changes in the cytoskeleton and exposure of phosphatidylserine on the outer leaflet of the plasma membrane [1,2]. Nevertheless, microparticles can easily be generated in vitro from aggregating platelets or from cultured cells following activation or apoptosis. Microparticles are also found circulating in the blood. Their numbers increase in patients exhibiting hypercoagulability and decrease in those with bleeding disorders [2,3]. Presence of microparticles has also been documented at sites of inflammation such as the acellular lipid core of the atherosclerotic plaque or the synovial fluid from patients with rheumatoid arthritis [3–6]. Furthermore, increased numbers of circulating microparticles have been reported in patients with acute coronary syndromes or other cardiovascular diseases [2,3,7]. Although plateletderived microparticles appear to be a significant part of the number of circulating shed membrane vesicles, particles from other cell type such as red blood cells, leukocytes, or endothelial cells also contribute to the plasmatic pool. For example, circulating endothelial microparticles can be taken as a hallmark of stress-injured or dying endothelial cells and may be recognized in the future as a marker of endothelial dysfunction [8].
Modularity, Self-Organization andComplexity Estimation: Three Foremost Supplies towardIntelligent Information Processing

Field: Computer Science (Physical Sciences)

Overthepastdecades, newapproaches based on Artificial NeuralNetworks (ANN)havebeenproposed to processcomplexinformation andtoovercomedifficult problems solution asthose related tooptimization, modeling, decision making, control, classification, datamining, nonlinear functions (behavior) approximation etc.. However, iflearning andgeneralization capabilities ofANNmadeappear anumber ofexpectation toemergeintelligent information processing, itisnowadmitted thatintelligent behavior requires more sophisticated mechanisms thanthoseperformed bythese simple model. Recent advances inneurobiology allowed highlighting someofkeymechanisms ofbiological intelligence. Amongthemonecanaccentuate brain's modular structure, it's self-organizing capabilities andit's complexity reducing ability. Themaingoalofthis paperistoshowhowthese foremost supplies couldbeembedded inintelligent artificial mechanisms in orderto designintelligent information processing systems.
Finite element modeling of hip resurfacing cup deformation

Field: Engineering (Physical Sciences)

Hip resurfacing arthroplasty is touted as an attractive alternative to total hip arthroplasty for treatment of severe joint pain and limited mobility in young patients because it is bone conserving and allows for a greater range of motion. There is concern in the orthopaedic community, however, regarding surgically-induced deformation of hip resurfacing cups. Cup deformation could potentially compromise the tight clearance between the femoral head and cup, resulting in increased wear, acoustic emissions, and joint binding. This phenomenon has been investigated both experimentally and with finite element analysis (FEA). Finite element studies have contributed significantly to our understanding of cup deformation, such as the effect of different cup dimensions on deformation results, but unfortunately such studies were deficient in a number of ways. The first objective of this thesis was to create a three-dimensional finite element model of resurfacing cup deformation that addressed the limitations of previous models pertaining to pelvic geometry, meshing, material properties, and cup insertion, in order to more fully elucidate cup deformation. The second objective was to demonstrate that two-dimensional characterization of cup deformation at the cup rim is insufficient, by more fully characterizing cup deformation in three-dimensions. The geometry was obtained via laser scanning and digital processing of a hemi-pelvis replica, meshing was performed without the use of shell elements, linear elasticity with strain-hardening after the onset of yielding was assigned to the cup and bone, and the most appropriate method for simulation of cup insertion was determined via two-dimensional axisymmetric analyses. Also, cup deformation was characterized in three-dimensions. The key findings of this thesis are that bone yield behaviour has important implications on press-fitting simulation, and the cup deforms irregularly and possibly plastically during press-fitting. A three-dimensional finite element model of resurfacing cup deformation that addressed the limitations of previous models was successfully created. Measurement of deformation at the rim of the resurfacing cup for characterization of cup deformation is insufficient; full characterization of cup deformation in three-dimensions is necessary. Future work should incorporate clinical testing to obtain model inputs such as impact and muscle forces, as well as model validation.
Mechanochemical‐Induced Swelling–Activation of a Gastric‐Deployable 4D‐Printed Polypill Inspired by Natural Hygromorphic Actuators

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

Gastroretentive drug delivery systems can improve adherence in patients with chronic diseases (CDs), but current options lack dose flexibility and involve complex fabrication methods. Inspired by the hygroscopic deformation observed in multilayered pine cone scales, wherein hydration of the outer active layer induces cone closure, a one‐step fabrication method of a personalized 4D‐printed water‐actuated four‐arm polypill is demonstrated in this study. The bilayer‐arm polypill self‐deploys upon ingestion to prolong gastric retention and sustain drug release. By inversing the orientation of the swellable active layer at the polypill arms compared to pine cone scales, a differential swelling strain develops generating bending force that enables polypill deployment to constrain passage through the pylorus. Finite‐element analysis is used to model spatial changes in polymer phase swelling to ensure adequate deployment within the timeframe of gastric emptying. In a stomach model, the polypill expanded to 30 mm over 2 h, exceeding the diameter of the stomach model's distal end. In an in vitro release screening, biocompatible polymer composites capable of providing up to 6 days of release for a three‐drug combination for tuberculosis–HIV coinfected patients are identified. The bioinspired 4D‐printed polypill can serve as drug delivery platform for a range of CDs.
Annealing behavior of In implanted in Si studied by perturbed angular correlation

Field: Physics and Astronomy (Physical Sciences)

The perturbed angular correlation technique has been used to study the local environment of 111In implanted to low doses at room temperature into Si as a function of postimplantation annealing temperature. At annealing temperatures corresponding to those where previous electrical measurements have observed reverse annealing behavior, we find evidence for the displacement of In to regions of lattice disorder. This is in contrast to results of ion-beam channeling experiments on heavy group-III impurities in Si which have been interpreted to indicate the displacement of the impurity to a unique regular tetrahedral interstitial site.
Effect of Heartfulness Meditation on Cortisol Levels and Vital Parameters in Healthy Female Medical StudentsA Prospective Longitudinal Study

Field: Medicine (Health Sciences)

Introduction: Medical education has been reported to be one of the most stressful academic curriculum worldwide, with a potential of negatively affecting the physical and mental health of medical students. Meditation is a self-produced relaxation technique which restores the mental peace by relieving emotional and physiological stress and is an accepted therapy to reduce stress. Aim: To study the effect of heartfulness meditation on cortisol levels and vital parameters in healthy female medical students. Materials and Methods: This study was a prospective longitudinal study conducted in the department of physiology at Sri Padmavathi Medical College for women, SVIMS, Andhra Pradesh, India. Sixty female medical students of age group 18 to 25 years were undergone heartfulness meditation training for a period of 6 months from September 2021 to February 2022 Baseline measurements of cortisol, heart rate, Respiratory Rate (RR) and Blood Pressure (BP) were taken at the beginning of the session and after 6 months of intervention program i.e., from September 2021 to February 2022. Later pre and postvalues were compared and analysed statistically by using paired sample t-test and the p-value <0.05 or 5% was used as level of significance for comparison. For data analysis Statistical Package for Social Sciences (SPSS) version 19 was used. Results: The vital signs and cortisol levels in female medical students were significantly changed after practicing heartfulness meditation for six months. There was a significant decrease in Pulse Rate (PR) (p<0.001), RR (p<0.001), Systolic Blood Pressure (SBP) (p<0.001) and Diastolic Blood Pressure (DBP) (p<0.001) and cortisol levels (p<0.001) after 6 months practice of heartfulness meditation. Conclusion: The study concluded that heartfulness meditation had a positive effect on sympathovagal balance and also it was effective in reducing stress levels in medical students.
Bethe ansatz solutions for Temperley-Lieb quantum spin chains

Field: Mathematics (Physical Sciences)

We solve the spectrum of quantum spin chains based on representations of the Temperley-Lieb algebra associated with the quantum groups U-q(X-n) for X-n = A(1), B-n, C-n and D-n. The tool is a modified version of the coordinate Bethe ansatz through a suitable choice of the Bethe states which give to all models the same status relative to their diagonalization. All these models have equivalent spectra up to degeneracies and the spectra of the lower-dimensional representations are contained in the higher-dimensional ones. Periodic boundary conditions, free boundary conditions and closed nonlocal boundary conditions are considered. Periodic boundary conditions, unlike free boundary conditions, bleak quantum group invariance. For closed nonlocal cases the models are quantum group invariant as well as periodic in a certain sense.
Localization and assembly into the Escherichia coli envelope of a protein required for entry of colicin A

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Mutations in tolQ, previously designated fii, render cells tolerant to high concentrations of colicin A. In addition, a short deletion in the amino-terminal region of colicin A (amino acid residues 16 to 29) prevents its lethal action, although this protein can still bind the receptor and forms channels in planar lipid bilayers in vitro. These defects in translocation across the outer membrane in the tolQ cells or the colicin A mutant cannot be bypassed by osmotic shock. The TolQ protein, which is constitutively expressed at a low level, was studied in recombinant plasmid constructs allowing the expression of various TolQ fusion proteins under the control of the inducible caa promoter. The TolQ protein was thus "tagged" with an epitope from the colicin A protein for which a monoclonal antibody is available. A fusion protein containing the entire TolQ protein plus the 30 N-terminal residues of colicin A was shown to complement the tolQ mutation. Pulse-chase labeling followed by gradient fractionation indicated that the bulk of the overproduced fusion protein was rapidly incorporated into the inner membrane, with small amounts localized to regions corresponding to the attachment sites between inner and outer membranes and to the outer membrane itself. However, most of the protein was rapidly degraded, leaving only that localized to the attachment sites and the outer membrane remaining at very late times of chase.
Blending video games with learning: Issues and challenges with classroom implementations in the Turkish context

Field: Social Sciences (Social Sciences)

Abstract The research design for this study focuses on examining the core issues and challenges when video games are used in the classroom. For this purpose three naturalistic contexts in Turkey were examined in which educational video games were used as the basis for teaching units on world continents and countries, first aid, and basic computer hardware and peripherals, in primary, secondary and higher education contexts respectively. Methods employed in the data collection include observing lessons, taking field notes, interviewing students and teachers, saving online discourse data, and collecting student artifacts and reflections. Findings identified issues related to (1) the design of the video game environment, (2) school infrastructure, (3) the nature of learning, the role of the teacher and classroom culture, and (4) engagement.
Hubert H. Schneider. Semantics of the predicate calculus with identity and the validity in the empty individual-domain. Portugaliae mathematica, vol. 17 (1958), pp. 85–96. - Hubert H. Schneider. A syntactical characterization of the predicate calculus with identity and the validity in all individual-domains. Portugaliae mathematica, vol 20 (1961), pp. 105–117.

Field: Mathematics (Physical Sciences)

Hubert H. Schneider. Semantics of the predicate calculus with identity and the validity in the empty individual-domain. Portugaliae mathematica, vol. 17 (1958), pp. 85–96. - Hubert H. Schneider. A syntactical characterization of the predicate calculus with identity and the validity in all individual-domains. Portugaliae mathematica, vol 20 (1961), pp. 105–117. - Volume 30 Issue 3
Characterization of Elastin-Like Polypeptides Using Viscometry

Field: Chemistry (Physical Sciences)

Elastin-like polypeptides (ELPs) are a class of polypeptide polymers that are gaining interest in various potential applications. These polymers are responsive to the changes in their environment by exhibiting conformational changes and aggregation. Monodisperse elastin-like polypeptides, (GVGVP)40, (GVGVP)40-foldon, and (GVGVP)60-foldon are made in bacterial expression system. An Ubbelohde capillary viscometer was set up to characterize the structural changes of these ELPs in phosphate buffered saline (PBS) solution. For the ELP-foldon, the relative viscosity measurements were utilized to calculate the intrinsic viscosities using Kraemer and Huggins equations. The known molecular weights of the ELPs and the experimentally determined intrinsic viscosities facilitated the calculation of the Mark-Houwink-Sakurada constants. The value of the exponential a in the Mark-Houwink-Sakurada equation was 0.69 at 20°C and it decreased as the temperature increased until it reached 0.51 at 26°C. The observed changes in a indicate that the conformation of the polymer coils changes from expanded and hydrated coils to theta coils. Viscosity measurements were limited in this project by concentration, since low concentrations produced small specific viscosities with large errors. A second limitation on the viscosity measurements was the aggregation of the polymers. The polymers aggregated at their phase transition temperature, Tt, and they phase separated
Effect of nitrogen and sulphur on the growth and yield of T. Aman rice (BRRI Dhan 87)

Field: Agricultural and Biological Sciences (Life Sciences)

Efficient use of nitrogen (N) and sulphur (S) is crucial for enhancing rice productivity in Bangladesh, where nutrient deficiencies significantly limit yields. This study aimed to evaluate the combined effects of N and S fertilization on the growth, yield, and soil fertility of traditional T. Aman rice (BRRI Dhan 87). A field experiment was conducted during the 2019 T. Aman season at the Agronomy Field Laboratory, Sher-e-Bangla Agricultural University, Dhaka, following a randomized complete block design (RCBD) with 12 N-S fertilizer combinations and three replications. Results revealed that N and S significantly (p<0.05) influenced plant growth, yield attributes, and soil properties. The highest grain yield (5.67 t ha-¹) and straw yield (6.88 t ha-¹) were recorded under the N120S12 treatment, representing a 98.9% yield increase compared to the control (2.85 t ha-¹). The same treatment produced the tallest plants (131.78 cm), highest effective tillers (15.33 hill-¹), filled grains (140.37 panicle-¹), and 1000-grain weight (57.00 g). Post-harvest soil analysis showed improved organic matter (1.42%), total N (0.66%), and available P (27.03 ppm) under N120S12. The findings manifest that an integrated application of 120 kg N ha-¹ and 12 kg S ha-¹ optimizes yield performance and enhances soil fertility while minimizing resource losses. These results provide a sustainable nutrient management strategy for improving rice productivity in Bangladesh in similar agro-ecological zones.
Investigating Top-k White-Box and Transferable Black-box Attack

Field: Computer Science (Physical Sciences)

Existing works have identified the limitation of top-1 attack success rate (ASR) as a metric to evaluate the attack strength but exclusively investigated it in the white-box setting, while our work extends it to a more practical black-box setting: transferable attack. It is widely reported that stronger I-FGSM transfers worse than simple FGSM, leading to a popular belief that transferability is at odds with the white-box attack strength. Our work challenges this belief with empirical finding that stronger attack actually transfers better for the general top-k ASR indicated by the interest class rank (ICR) after attack. For increasing the attack strength, with an intuitive analysis on the logit gradient from the geometric perspective, we identify that the weakness of the commonly used losses lie in prioritizing the speed to fool the network instead of maximizing its strength. To this end, we propose a new normalized CE loss that guides the logit to be updated in the direction of implicitly maximizing its rank distance from the ground-truth class. Extensive results in various settings have verified that our proposed new loss is simple yet effective for top-k attack. Code is available at: https://bit.ly/3uCiomP
Comment and Reply on “Timing of terrane accretion in eastern and east-central Maine”

Field: Earth and Planetary Sciences (Physical Sciences)

Research Article| December 01, 1986 Comment and Reply on “Timing of terrane accretion in eastern and east-central Maine”: REPLY Allan Ludman Allan Ludman 1Department of Geology, Queens College of the City University of New York, Flushing, New York 11367-0904 Search for other works by this author on: GSW Google Scholar Geology (1986) 14 (12): 1052. https://doi.org/10.1130/0091-7613(1986)14<1052:CAROTO>2.0.CO;2 Article history first online: 01 Jun 2017 Cite View This Citation Add to Citation Manager Share Icon Share MailTo Twitter LinkedIn Tools Icon Tools Get Permissions Search Site Citation Allan Ludman; Comment and Reply on “Timing of terrane accretion in eastern and east-central Maine”: REPLY. Geology 1986;; 14 (12): 1052. doi: https://doi.org/10.1130/0091-7613(1986)14<1052:CAROTO>2.0.CO;2 Download citation file: Ris (Zotero) Refmanager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentBy SocietyGeology Search Advanced Search Abstract No Abstract Available. This content is PDF only. Please click on the PDF icon to access. First Page Preview Close Modal You do not have access to this content, please speak to your institutional administrator if you feel you should have access.
Investigating Acceptance of Nursing Information Systems through UTAUT Lens

Field: Health Professions (Health Sciences)

It is widely known that nurses are pivotal in coordinating and communicating patient care information in the complex network of healthcare professionals and service delivery. Yet, despite their pivotal role, information communication technologies have historically rarely been designed around nurses' operational needs. This could explain the poor integration of technologies into nursing work processes and consequent rejection by nursing professionals. The complex nature of acute care delivery in hospitals and the frequently interrupted patterns of nursing work suggest that nurses require flexible intelligent systems that can support and adapt to their variable workflow patterns. This study is designed to explore nurses' initial reactions to a new integrated point of care solution for acute healthcare contexts. We report on the first stage of a longitudinal project to use an innovative approach involving nurses in the development and refinement of this solution. Unified Theory of Acceptance and Use of Technology was used to evaluate acceptability of the proposed system by nurses.
Supplementary Table 1 from Transcriptional Profiling of Melanoma Sentinel Nodes Identify Patients with Poor Outcome and Reveal an Association of CD30<sup>+</sup> T Lymphocytes with Progression

Field: Medicine (Health Sciences)

<p>XLSX file - 15K, Supplementary Table S1.Clinicopathological data for the SNB samples analyzed in the training and validation studies.</p>
Entrapment: From the objection from temptation to the objection from moral alliance

Field: Arts and Humanities (Social Sciences)

Entrapment involves two parties: the agent, who entraps, and the target, who is \nentrapped. When entrapment occurs, the agent procures the target’s act by recommending, \nrequesting or enjoining its performance. When an agent intentionally tempts a target, the agent \npresents the target with the opportunity to perform an act, with the intention that the target will \nexperience an urge to perform it. Mere virtue testing is weaker: here, the agent intentionally \npresents the opportunity, but without the intention to tempt. One moral objection to entrapment \nhas it that the entrapment is impermissible because it involves temptation. With the benefit of \nthe aforementioned background material, we scrutinize, and reject, both this objection and a \nlogically weaker one that is recoverable from it. We argue, instead, that when entrapment \nmorally allies the agent, in a manner that we explain, with the target’s act then it is thereby \nimpermissible.