jimnoneill/paper-to-field-training huggingface dataset:
Comparison between reverse transcription-polymerase chain reaction and immune enzyme assays in the diagnosis of hepatitis C virus infection.

Field: Medicine (Health Sciences)

This is the first study of HCV infection performed in Romania by reverse transcription-polymerase chain reaction (RT-PCR). We set up our own protocol, using "nested" primers located in the 5' UTR of HCV. Thirty two patients, 16 with chronic hepatitis, 7 with hepatic cirrhosis and 9 without chronic hepatic disease were investigated. The assignment of each patient to one of the groups was based on clinical and laboratory criteria, especially transaminase levels and hepatic biopsy findings. In 14 out of 16 (87.5%) chronic hepatitis cases and in 6 cases of hepatic cirrhosis out of 7 (85.7%), there was good agreement between RT-PCR and ELISA results. Transaminase levels were concordant with RT-PCR results in 27 of 29 cases (93.1%) but in only 21 of 29 cases (72.4%) transaminase levels were in agreement with ELISA results. In two patients treated with interferon, transaminase levels and the other clinical and laboratory parameters fell in the normal range in parallel with the disappearance of viremia, whereas anti-HCV antibodies were still detectable. RT-PCR has a higher specificity in detecting the etiology of hepatic diseases if compared to ELISA and an at least equal sensitivity. The method proves to be the best means for the confirmation of HCV infection, and for the monitoring of interferon therapy.
Involvement of Rev1 in alkylating agent‐induced loss of heterozygosity in Oryzias latipes

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

Abstract Translesion synthesis (TLS) polymerases mediate DNA damage bypass during replication. The TLS polymerase Rev1 has two important functions in the TLS pathway, including dCMP transferase activity and acting as a scaffolding protein for other TLS polymerases at the C‐terminus. Because of the former activity, Rev1 bypasses apurinic/apyrimidinic sites by incorporating dCMP, whereas the latter activity mediates assembly of multipolymerase complexes at the DNA lesions. We generated rev1 mutants lacking each of these two activities in Oryzias latipes (medaka) fish and analyzed cytotoxicity and mutagenicity in response to the alkylating agent diethylnitrosamine (DENA). Mutant lacking the C‐terminus was highly sensitive to DENA cytotoxicity, whereas mutant with reduced dCMP transferase activity was slightly sensitive to DENA cytotoxicity, but exhibited a higher tumorigenic rate than wild‐type fish. There was no significant difference in the frequency of DENA‐induced mutations between mutant with reduced dCMP transferase activity and wild‐type cultured cell. However, loss of heterozygosity (LOH) occurred frequently in cells with reduced dCMP transferase activity. LOH is a common genetic event in many cancer types and plays an important role on carcinogenesis. To our knowledge, this is the first report to identify the involvement of the catalytic activity of Rev1 in suppression of LOH.
VA psychologists’ professional practices and attitudes toward tele-neuropsychology among a tele-neuropsychology interest group within the Veterans Health Administration

Field: Health Professions (Health Sciences)

To provide understanding of practices and attitudes toward tele-neuropsychology (teleNP) among Veterans Health Administration (VA) psychologists who have joined a related community of practice. Several VA psychologists (the authors) developed this survey to better understand dissemination of teleNP and attitudes toward teleNP among those involved in a VA teleNP community of practice. We contacted VA psychologists within this group to complete the survey. The survey was open from July to August 2021, during which time a total of 62 VA psychologists participated. Response rate was estimated to be 41% of those receiving the survey (62 respondents). Approximately two thirds of those completing the survey reported current practice of teleNP (68%; n = 42). In contrast, only 25% of the entire sample (n = 15) conducted any teleNP pre-pandemic. Job satisfaction related to being able to perform teleNP is high. Support for continued and increased use of teleNP is high, with most respondents (84%) indicating they will be at least somewhat likely to practice teleNP post-pandemic. The survey provides increased support for the use of teleNP by VA psychologists who responded to the survey, with significantly increased adoption since the Covid-19 pandemic, and greater likelihood of intention to use teleNP post pandemic.
A Constrained-Coding Alternative to MPPM

Field: Computer Science (Physical Sciences)

Multipulse pulse position modulation (MPPM) has been widely proposed to improve data rate over traditional pulse position modulation (PPM) in free-space optical communication systems. Encoders for MPPM are typically lookup-table-based, thus restricting the practical size of MPPM codebooks. Power-of-two-sized MPPM codebooks typically do not have an efficient soft-in soft-out decoder, making them poorly suited for concatenation with an outer code under iterative decoding. In this paper, a new coding technique based on constrained coding is introduced that allows construction of codes which have an efficient encoding algorithm. More importantly, these new codes are suitable for iterative soft-decision decoding in concatenation with an outer error-correcting code. Simulation results for both the Gaussian and Poisson channels show that a serial concatenation with an outer low-density parity-check code (LDPC) can achieve between 2 to 3 dB coding gain over comparable Reed-Solomon and LDPC-coded MPPM systems.
Application of Multi-hierarchical Fuzzy AHP Comprehensive Evaluation on Economical Campus Evaluation

Field: Decision Sciences (Social Sciences)

The paper develops a multi-hierarchical fuzzy AHP (Analytic Hierarchy Process) comprehensive evaluation model to evaluate and rank the economical campus. The study adopts AHP method, one of the multiple attribute decision-making approaches to calculate the relative weights of sub-attributes. An example calculation is provided to offer ways to improve the efficiency of economical campus construction. The evaluation results reveal that the utilization of energy-saving hardware and technology has the greatest impact on economical campus comprehensive evaluation. It is further revealed that the cost-saving measures and saving effect should be equally important in the economical campus comprehensive evaluation. Therefore, this paper proposes a framework of a more suitable approach to achieving economical campus, and help decision-makers choose the most appropriate methods to ensure more high efficiency campus.
Rectal adenocarcinoma: intratumoral oxygenation level assessed with BOLD MR and tumour angiogenesis

Field: Medicine (Health Sciences)

Poster: ECR 2013 / C-0486 / Rectal adenocarcinoma: intratumoral oxygenation level assessed with BOLD MR and tumour angiogenesis by: R. Xu1, W. Li2, X. Wang1; 1Shenyang/CN, 2Mudanjiang/CN
Ridge Network Detection in Crumpled Paper via Graph Density Maximization

Field: Computer Science (Physical Sciences)

Crumpled sheets of paper tend to exhibit a specific and complex structure, which is described by physicists as ridge networks. Existing literature shows that the automation of ridge network detection in crumpled paper is very challenging because of its complex structure and measuring distortion. In this paper, we propose to model the ridge network as a weighted graph and formulate the ridge network detection as an optimization problem in terms of the graph density. First, we detect a set of graph nodes and then determine the edge weight between each pair of nodes to construct a complete graph. Next, we define a graph density criterion and formulate the detection problem to determine a subgraph with maximal graph density. Further, we also propose to refine the graph density by including a pairwise connectivity into the criterion to improve the connectivity of the detected ridge network. Our experimental results show that, with the density criterion, our proposed method effectively automates the ridge network detection.
Aza-Morita-Baylis-Hillman reactions of N-(benzylidene)polyfluoroanilines with methyl acrylate and acrylonitrile

Field: Chemistry (Physical Sciences)

Aza-Morita-Baylis-Hiliman reactions of N-(benzylidene)polyfluoroanilines 1 with methyl acrylate or acrylonitrile were studied. It was found that Lewis base, solvent and reaction temperature can significantly affect the reaction. Using 3-hydroxyquinuclidine (3-HQD) as a Lewis base in the reactions of 1 with methyl acrylate in DMF, the normal aza-Morita-Baylis-Hillman adducts 3 were formed in moderate to excellent yields. For the reactions of I with acrylonitrile, 1,4-diazabicyclo[2.2.2] octane (DABCO) is the best Lewis base giving the corresponding aza-Morita-Baylis-Hillman adducts 4 as the sole product in good to moderate yield. However, upon treatment of I with acrolein 2c, the Corresponding reaction did not occur even in the presence of a variety of catalysts. (c) 2005 Elsevier B.V. All rights reserved.
Real-time fracture monitoring in Engineered Geothermal Systems with seismic waves

Field: Earth and Planetary Sciences (Physical Sciences)

As proposed, the main effort in this project is the development of software capable of performing real-time monitoring of micro-seismic activity recorded by an array of sensors deployed around an EGS. The main milestones are defined by the development of software to perform the following tasks: â¢ Real-time micro-earthquake detection and location â¢ Real-time detection of shear-wave splitting â¢ Delayed-time inversion of shear-wave splitting These algorithms, which are discussed in detail in this report, make possible the automatic and real-time monitoring of subsurface fracture systems in geothermal fields from data collected by an array of seismic sensors. Shear wave splitting (SWS) is parameterized in terms of the polarization of the fast shear wave and the time delay between the fast and slow shear waves, which are automatically measured and stored. The measured parameters are then combined with previously measured SWS parameters at the same station and used to invert for the orientation (strike and dip) and intensity of cracks under that station. In addition, this grant allowed the collection of seismic data from several geothermal regions in the US (Coso) and Iceland (Hengill) to use in the development and testing of the software.
Development of Churg‑Strauss syndrome with severe multiple mononeuropathy after leukotriene receptor antagonist treatment in one of the monozygotic twins with asthma

Field: Medicine (Health Sciences)

Several cases of Churg-Strauss syndrome (CSS) have been reported in asthmatic patients treated with leukotriene receptor antagonists (LTRAs). It is not clear whether LTRA is a causative factor in the development of vasculitis. We present the case of a 26-year-old patient, who developed severe central and peripheral neuropathy after a short-term treatment with LTRA, followed by gastrointestinal perforation and bleeding. The patient was successfully treated with high-dose glucocorticoids, immunoglobulins, and cyclophosphamide. His monozygotic twin brother treated for asthma does not meet classification criteria for Churg-Strauss syndrome at the moment, but his condition is being monitored. Both asthma and rheumatology specialists should consider the possibility of CSS development in patients treated with LTRAs.
Spectral asymptotics and metastability for the linear relaxation Boltzmann equation

Field: Mathematics (Physical Sciences)

We consider the linear relaxation Boltzmann equation in a semiclassical framework. We construct a family of sharp quasimodes for the associated operator which yields sharp spectral asymptotics for its small spectrum in the low temperature regime. We deduce some information on the long time behavior of the solutions with a sharp estimate on the return to equilibrium as well as a quantitative metastability result. The main novelty is that the collision operator is a pseudo-differential operator in the critical class S^{1/2} and that its action on the Gaussian quasimodes yields a superposition of exponentials.
Perspectives of Nautical Tourism in the Adriatic

Field: Social Sciences (Social Sciences)

Nautical tourism is sailing and nautical tourists stationing at cruising objects ( yachts, boats and ferry boats for personal or economic purposes, etc) as well as staying at ports of nautical tourism for recreation and relaxation. In this paper we will present trends in European nautical tourism: number of vessel, increasing average length of vessel on yearly berth, seasonality, increasing service quality, ecological consciousness and capacity of marinas. In the end we will give perspective for European nautical tourist until 2020.
Gateway-Assisted Retransmission for Lightweight and Reliable IoT Communications

Field: Computer Science (Physical Sciences)

Message Queuing Telemetry Transport for Sensor Networks (MQTT-SN) and Constrained Application Protocol (CoAP) are two protocols supporting publish/subscribe models for IoT devices to publish messages to interested subscribers. Retransmission mechanisms are introduced to compensate for the lack of data reliability. If the device does not receive the acknowledgement (ACK) before retransmission timeout (RTO) expires, the device will retransmit data. Setting an appropriate RTO is important because the delay may be large or retransmission may be too frequent when the RTO is inappropriate. We propose a Gateway-assisted CoAP (GaCoAP) to dynamically compute RTO for devices. Simulation models are proposed to investigate the performance of GaCoAP compared with four other methods. The experiment results show that GaCoAP is more suitable for IoT devices.
Intracranial Pressure Gradients Caused by Experimental Cerebral Ischemia and Edema

Field: Neuroscience (Life Sciences)

To assess the development and resolution of ischemic cerebral edema and brain swelling, measurements of intracranial pressure (ICP) were made in cats after the transorbital occlusion of one middle cerebral artery. Measurement of ICP gradients was difficult: epidural, subdural and intraventricular catheters caused brain damage or failed to function; the accuracy of a miniature strain gauge could not be determined after implantation; and absolute values for intradural pressures could not be obtained with epidural devices. However, variable increases of ICP were recorded on the sides of occlusion from three cats, and were directly related to the severity of the neurological deficits. On the sides opposite occlusion ICP increased slightly or not at all. Several days after occlusion ICP decreased and gradients could not be demonstrated with certainty. Thus, measurements of ICP gradients can be used to assess ischemic cerebral edema and brain swelling, but the usefulness of such measurements is limited at present by methodological problems.
Weisfeiler and Leman Go Loopy: A New Hierarchy for Graph Representational Learning

Field: Computer Science (Physical Sciences)

We introduce $r$-loopy Weisfeiler-Leman ($r$-$\ell{}$WL), a novel hierarchy of graph isomorphism tests and a corresponding GNN framework, $r$-$\ell{}$MPNN, that can count cycles up to length $r + 2$. Most notably, we show that $r$-$\ell{}$WL can count homomorphisms of cactus graphs. This strictly extends classical 1-WL, which can only count homomorphisms of trees and, in fact, is incomparable to $k$-WL for any fixed $k$. We empirically validate the expressive and counting power of the proposed $r$-$\ell{}$MPNN on several synthetic datasets and present state-of-the-art predictive performance on various real-world datasets. The code is available at https://github.com/RPaolino/loopy
A New Test System and a New Cause for Acquired Foveal Color-Vision Deficiency

Field: Medicine (Health Sciences)

The purpose of this paper is to show a new cause of a macular scotoma and an anomalous acquired color-vision deficiency in the clinical fovea caused by retina detachments and subsequent surgeries. This deficiency was measured with a visual test system composed of multiple lasers, a white light beam and dozens of targets that were projected on a computer monitor and printed on paper. Lasers were used, because they produce small monochromatic target dots, 0.07 degrees of visual angle (6 mm) in diameter. The outputs of the system were the subject’s perceived color matches. In experiments with small dots of laser light, colors were judged correctly by the right eye (OD): however, the left eye (OS) could not distinguish colors. For example, a green laser dot appeared green to his OD and white to his OS. Perceived color in the abnormal OS depended on the target’s hue, saturation, luminance, wavelength, size and position on the fovea. This subject has an acquired color-vision deficiency in the clinical fovea of his OS. These visual anomalies are consistent with damage to retinal ganglion cells. Strangely, his OS does not see negative-color afterimages.
The Usefulness Of Narrow Band Imaging Endoscopy For The Real Time Characterization Of Colonic Lesions

Field: Medicine (Health Sciences)

Abstract Narrow band imaging represents a promising endoscopic technique which allows real time characterization of colonic lesions by assessment of mucosal and vascular patterns. Due to the ability to make an optical biopsy, NBI could become a useful tool in clinical decisions regarding therapy and surveillance. The aim of this paper is to review the current knowledge on the optical diagnosis of colonic lesions by using NBI endoscopy. We reviewed research articles, reviews and meta-analyses from the PubMed and MEDLINE containing relevant data in this field. The validity of endoscopic criteria for the differentiation of adenoma and hyperplastic polyps, as well as of invasive cancer, has been evaluated in recent studies. Based on the prediction of polyp histology, new potential cost saving strategies have been proposed. Many reports are focused on the accuracy of optical biopsy by using NBI for predicting colonoscopy surveillance intervals and adenomatous histology in diminutive polyps, according to the Preservation and Incorporation of Valuable Endoscopic Innovations statement. Optical diagnosis is still under evaluation, and cannot yet be endorsed in routine practice. The high level of performance achieved by expert endoscopists needs to be replicated in the community utilizing reliable and standardized endoscopic criteria.
Theoretical Foundations of Fuzzy Bi-criterial Approach to Project Cost and Schedule Buffers Sizing

Field: Decision Sciences (Social Sciences)

The aim of this research was the trial of modelling and optimizing the time-cost trade-offs in project planning problem with taking into account the behavioral impact of performers’ (or subcontractors’) estimations of basic activity parameters. However, such a model must include quantitative measurements of budget and duration, so we proposed to quantify and minimize the apprehension of their underestimations. The base of the problem description contains both safe and reasonable amounts of work estimations and the influence factors matrix. We assumed also the pricing opportunity of performance improving. Finally we introduce fuzzy measurements for work amount.
Roughness of the Tooth Surface after Root Planing (Part II)

Field: Dentistry (Health Sciences)

In an attempt to determine how the degree of roughness of the polished dentin planes would be affected by several factors under root planing, morphological studies were made scanning-electoronmicroscopically.The results obtained were as follows:1) Under hand scaling, the folds were observed on the dentin surface followed by 2 strokes of all aplied forces and instrumental angles.2) The folds were smooth increasing with the strokes, but were gradually observed that the depth of defect was larger under the line-spot technique.3) On the roughness of the tooth surface under two types of ultrasonic sealers; in CAVITON, the particles of an indeterminate form were observed, on the other hand, many craters were observed in ODONTOSON.
The “Aqueous” Prins Reaction

Field: Chemistry (Physical Sciences)

[reaction: see text] In this communication we demonstrate that Prins cyclization reactions occur under very mild conditions when cyclic alpha,beta-unsaturated acetals are employed as oxocarbenium ion progenitors and allylsilanes are used as nucleophiles. Cyclizations proceed efficiently inside Lewis acidic micelles in water, demonstrating that colloidal suspensions can protect highly electrophilic intermediates from hydrolysis. Reactions are experimentally facile and useful in the preparation of a variety of vinyl- and aryl-substituted tetrahydropyrans with excellent stereocontrol.
The Effect of Resistance Interval Training by Intensity on Women’s Double Product and Blood Lipids

Field: Medicine (Health Sciences)

Purpose: The purpose of this study is to investigate the effects of intensity-specific training for 8 weeks on double product and blood lipids for women in their twenties.BR Method: The subjects of the study were women in their 20s living in the metropolitan area, who explained the purpose and method of this study in detail, and asked for consent from the people who voluntarily expressed their intention to participate. 22 subjects who volunteered were recruited. As the training method, high intensity interval training and moderate intensity interval training were applied, and the exercise period was set at 8 weeks. The homogeneity of the momentum between each training was secured through preliminary measurement. The measurement variables were double product and blood lipid. The statistical method was SPSS 25.0 version, and the mean and standard deviation were calculated using descriptive statistical analysis. Repeated measurement ANOVA was used to verify the effect of training for 8 weeks. The differences between groups were analyzed using a paired t-test. All statistical significance levels were set to α=.05.BR Result: The results of this study are as follows. 1) As a result of the double product, both high intensity interval training and moderate intensity interval training were improved (p.05, p.01). 2) In the case of blood lipids, HDL-C variables were significantly increased in the high-intensity interval training group (p.05).BR Conclusion: As a result of applying interval training by intensity to women, double product is improved in all training groups, and improvement in blood lipids is insignificant, but it is thought to be effective in the long term. Therefore, high-intensity interval training can help maintain the health of women in their twenties, and it is considered to be more effective training because it can also save time.