jimnoneill/paper-to-field-training huggingface dataset:
Properties of progestin-binding protein in benign hypertrophic human prostate.

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

RU 27987 is a new ligand for progesterone receptor and binds in high affinity to nuclei of target tissues of progesterone. Using this compound, progestin-binding components in the benign hypertrophic human prostate were studied, and compared with those examined with R 5020, a conventional ligand, in the study of progesterone receptor. In cytosols, the binding affinity of RU 27987 was higher than that of R 5020, and the number of maximum binding sites for RU 27987 seemed to be large but correlated well with those of R 5020. The binder for RU 27987 sedimented at 8.6 S, and the binding was specific to progestational steroids, indicating that binding properties of this binder in the cytosols are identical to those for R 5020. Although there was no binding with R 5020 in the nuclear extract, a small amount of specific binding with RU 27987 was detected. However, the cytosol bound with RU 27987 was not retained in DNA Sepharose and no specific binder for RU 27987 in the nuclear extract was observed in a sucrose density gradient centrifugation. From these observations, it was assumed that the nuclear binding observed was attributable to contamination of the cytosolic binder. The results obtained in the present study suggest that the progestin-binding component in the benign prostatic hypertrophy is not the progesterone receptor but a high affinity binder for progestins whose physiological role is not clear at present.
Characterization of the causality of general dynamic systems

Field: Mathematics (Physical Sciences)

Abstract This paper treats the non-anticipation type causality in the framework of the mathematical general systems theory and gives a necessary and sufficient condition for the causality of a general dynamic system under the output completeness condition. The output completeness condition is demonstrated to hold for usual systems dealt with in systems theory including linear differential equation systems and finite automata. Finally, as an application of the necessary and sufficient condition causality properties are examined for several systems. In particular, a condition is found for a general linear time system to have a linear causal initial state representation.
MultiTex RCT – a multifaceted intervention package for protection against cotton dust exposure among textile workers – a cluster randomized controlled trial in Pakistan: study protocol

Field: Health Professions (Health Sciences)

Abstract Background In the Pakistani textile industry the prevalence of workplace respiratory illnesses, including byssinosis, is high. This study aims to determine the effectiveness of a multifaceted intervention package in reducing dust levels in cotton mills, decreasing the frequency of respiratory symptoms among cotton textile workers, and improving their lung function. Methods/design We will conduct a cluster-randomized controlled trial at 28 textile mills in Karachi. The intervention will comprise: training in occupational health for all workers and managers backed by regular refresher sessions; the formation of workplace committees to draw up, agree and promote a health and safety plan that includes wet mopping, safe disposal of cotton dust, and the use of simple face masks, as well as further publicity about the risks from cotton dust; and provision of adequate supplies of face masks to support the health and safety plan. Participating mills will be randomized to intervention and control arms following a baseline survey. The impact of the intervention will be determined through follow-up surveys conducted at 3, 12 and 18 months. Data collection in the surveys will include spirometry, questionnaire-based interviews and cotton dust measurements. Discussion If successful, the study may pave the way for simple, low-cost interventions that can help reduce cotton dust levels in textile mills, and improve the respiratory health of textile workers in developing countries such as Pakistan.
Diffusion in Sugar Solutions. IV. The Onsager Diffusion Coefficients for Glucose Diffusing in Sucrose Solutions

Field: Chemistry (Physical Sciences)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiffusion in Sugar Solutions. IV. The Onsager Diffusion Coefficients for Glucose Diffusing in Sucrose SolutionsF. E. Weir and Malcolm DoleCite this: J. Am. Chem. Soc. 1958, 80, 2, 302–306Publication Date (Print):January 1, 1958Publication History Published online1 May 2002Published inissue 1 January 1958https://pubs.acs.org/doi/10.1021/ja01535a013https://doi.org/10.1021/ja01535a013research-articleACS PublicationsRequest reuse permissionsArticle Views107Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
C asey, R. G . (1890–1976)

Field: Social Sciences (Social Sciences)

R. G. Casey (1890–1976) was Australia's foremost diplomat in the middle decades of the twentieth century, serving in London, Washington, the Middle East, and South Asia before becoming foreign minister (1951–60). His principal achievements were the cementing of relations with the United States and Britain and fostering Australia's relations with its regional neighbors during the Cold War.
Pharmacology and Molecular Identity of Serotonin Receptor in Bivalve Mollusks

Field: Pharmacology, Toxicology and Pharmaceutics (Life Sciences)

It is now known that 5-HT regulates several neurobehavioral systems such as mood, appetite, sleep, learning, and memory. It also plays critical roles in the physiological functions of peripheral organs involved in stress, growth, and reproduction in the animal kingdom. 5-HT content has seen to be higher in the nervous system of bivalves than those of other examined invertebrates and vertebrates. Thus, bivalves have been considered as an excellent model to investigate 5-HT functions in neurological and peripheral systems. The present study reviews knowledge on 5-HT signaling mediated through 5-HT receptor and its physiological contribution to regulate reproduction in bivalves. Two G-protein-coupled 5-HT1-like receptors have been cloned in bivalve species. However, binding affinities of the 5-HT agonists and antagonists to the isolated plasma membrane proteins and their effects on spawning in bivalves suggest the presence of a single or mixed 5-HT1-, 5-HT2-, and 5-HT3-like receptors. It has suggested that the 5-HT-like receptors in bivalves are distinct from those of mammalian 5-HT receptors due to pharmacological properties. The present review pays a special attention to future research perspectives to better understand 5-HT regulation of reproduction in bivalves, which can provide us with satisfactory knowledge to elucidate reproductive disorders associated with dysfunctions of the neurotransmitter system.
Dirençliliğin Temeli

Field: Social Sciences (Social Sciences)

The concept of resilience has been described in different ways since 1970s once mentioning in ecology and going through conceptual framework in disaster field. Each new definition makes the meaning broader so that the point we have reached today, resilience has a comprehensive meaning but less quantifiable (performance measures are defined by Bruneau et al, 2003). On the other hand as Rose (2007) underlined, the term of “resilience is in danger of becoming a vacuous buzzword from overuse and ambiguity” such as the term of “sustainability” in 1990s.
Effect of footwear features on the gait muscle activity of young, middle - aged and older adults

Field: Health Professions (Health Sciences)

In light of today’s society, Singapore is witnessing a surge of her senior population expedited by the low birth rates, the post-war baby boomers and the lengthened life expectancy of the modern population. As we age, our muscle mass and strength start to decline, increasing the vulnerability of suffering from age-related muscle loss disorder, for instance, sarcopenia, which is the gradual and degenerative loss of muscles mass prevalent in the elderly people. Notwithstanding the age, research has shown that performing regular exercises, such as taking frequent walks, can help to minimize the associated condition. Various footwear features can play an essential role in shaping the way we walk and have different effects on our gait cycles. Therefore, the purpose of this project is to identify and compare the different footwear to explore how the different features can affect the lower extremity muscles of middle and older adults in the gait cycle. From the results, we aim to explore and to determine different optimal features that will help reduce the deterioration of the leg muscle health among the middle and older adults. Three different age groups of subjects were tested; young (20-30 years old), middle-aged (40-60 years old) and older adults (60+ years old). Ten lower extremity muscles were studied and the effects of footwear during the different phases of the gait cycle were analyzed. These muscles activities were recorded using the wireless surface electromygraphy (SEMG) system and further analysed by MEGAWINTM software.
King David I and the Honour of Lancaster

Field: Arts and Humanities (Social Sciences)

King David I and the Honour of Lancaster Get access G.W.S BARRROW G.W.S BARRROW Search for other works by this author on: Oxford Academic Google Scholar The English Historical Review, Volume LXX, Issue CCLXXIV, January 1955, Pages 85–89, https://doi.org/10.1093/ehr/LXX.CCLXXIV.85 Published: 01 January 1955
Compliance with joint commission measures in state‐designated stroke centers

Field: Health Professions (Health Sciences)

BACKGROUND Comparison of state‐designated primary and comprehensive stroke centers (PSCs and CSCs) with regard to adherence to nationally accepted performance standards are scarce. The objective of this study was to examine if a significant association exists between level of designation and fulfillment of Joint Commission (JC) stroke core measures. METHODS A retrospective comparative data analysis of the New Jersey acute stroke registry for the calendar years 2010 and 2011 was performed. JC core measures were compared by hospital level (PSCs vs CSCs). Adjusted odds ratios (aOR) were estimated for association between hospital levels and fulfillment of JC core measures. Median door‐to‐thrombolytic time was also compared. RESULTS There were 36,892 acute stroke admissions. PSCs had 60% of the patients, whereas CSCs had 40%. Hemorrhagic stroke admissions were about 2 times more frequent at CSCs than PSCs (13.3% and 7.1%, respectively). CSCs adhered better to 6 of the 8 JC measures than PSCs. Of eligible patients, 19.5% received thrombolytic therapy at CSCs compared to 9.6% at PSCs, with a 44% difference in provision of thrombolytic therapy (aOR = 0.28, 95% confidence interval: 0.24‐0.34). Median door‐to‐thrombolytic drug times was 65 minutes at CSCs compared to 74.0 minutes at PSCs ( P < 0.0001). CONCLUSIONS New Jersey state‐designated CSCs are better at adhering to the JC core stroke measures and have shorter door‐to‐thrombolytic drug times. Journal of Hospital Medicine 2014;9:88–93. © 2013 Society of Hospital Medicine
Light-driven protonation changes of internal aspartic acids of bacteriorhodopsin: an investigation of static and time-resolved infrared difference spectroscopy using [4-13C]aspartic acid labeled purple membrane

Field: Biochemistry, Genetics and Molecular Biology (Life Sciences)

The molecular events during the photocycle of bacteriorhodopsin have been studied by the method of time-resolved and static infrared difference spectroscopy. Characteristic spectral changes involving the C=O stretching vibration of protonated carboxylic groups were detected. To identify the corresponding groups with either glutamic or aspartic acid, BR was selectively labeled with [4-13C]aspartic acid. An incorporation of ca. 70% was obtained. The comparison of the difference spectra in the region of the CO2- stretching vibrations of labeled and unlabeled BR indicates that ionized aspartic acids are influenced during the photocycle, the earliest effect being observed already at the K610 intermediate. Taken together, the results provide evidence that four internal aspartic acids undergo protonation changes and that one glutamic acid, remaining protonated, is disturbed. The results are discussed in relation to the various aspects of the proton pumping mechanism, such as retinal isomerization, charge separation, pK changes, and proton pathway.
Condition Monitoring of Three-Phase Induction Motor

Field: Engineering (Physical Sciences)

Analysis of stator current and vibration of induction motor has long been used, in researches as well as industries, for the condition monitoring purpose. This paper presents the hardware results of three phase induction motor condition monitoring by current and vibration analysis, presenting one novel diagnosis method while analyzing the frequency spectra. Here current and vibration data are collected with the help of Digital Storage Oscilloscope and Vibration Analyzer respectively. These collected data are used to obtain frequency components of current and vibration with the help of MATLAB program. Later, the set of the most dominating frequency components of current and vibration are compared with that of healthy motor in order to establish the healthy/faulty condition. A 3 HP, 2.2 KW, three-phase induction motor has been used for analysis purpose. Three types of major faults, namely, stator inter turn short, rotor broken bar and bearing defect are considered. The proposed method proves to be quite successful in predicting rotor and bearing faults, while not being so successful in detecting stator inter-turn faults.
Does Income Inequality Lead to Consumption Inequality? Evidence and Theory

Field: Economics, Econometrics and Finance (Social Sciences)

The Center for Financial Studies is a nonprofit research organization, supported by an association of more than 120 banks, insurance companies, industrial corporations and public institutions. Established in 1968 and closely affiliated with the University of Frankfurt, it provides a strong link between the financial community and academia. The CFS Working Paper Series presents the result of scientific research on selected top-ics in the field of money, banking and finance. The authors were either participants in the Center´s Research Fellow Program or members of one of the Center´s Research Pro-jects. If you would like to know more about the Center for Financial Studies, please let us know of your interest.
Effects and Ecological Significance of Soil-inhabiting Microorganisms in the Formation of Biological Soil Crusts

Field: Agricultural and Biological Sciences (Life Sciences)

Biological soil crusts formed under the different combinations of mosses, lichens, liverworts, algae, fungi and soil-inhabiting microorganisms are quite common and widespread in the desert regions all over the world thanks to their extraordinary adaptability and surviving capability under the severe environment, such as the high temperature, pH values and salinity. It is revealed that the crusts may be an important source of fixed carbon in the sparsely vegetated areas in arid regions. In the successional pathways of the crust communities, the pioneers in colonizing the soil surface are the soil-inhabit ing microorganisms. Stabilization of sand dunes occurs after the colonization by the filamentous cyanobacteria, which may constitute a prominent crust The polysac charides produced by these cyanobacteria and by soil-inhabiting algae form a mucilaginous sheath on the soil sur face slightly binding the soil surface particles. The high holding capacity of moisture and the typical polysaccha rides enhance further the crust development and facilitate the colonization by other organisms, such as the overground cyanobacteria, soil-inhabiting algae, mosses and lichens. Many studies have revealed that there is a close relation between the growth and activation of soil-inhabiting microorganisms and the soil enzyme activation The quantity, distribution and composition of soil-inhabiting microorganisms vary with soil depth and location of sand dunes, and are also affected by seasons and vegetation situation. The change of physiological metabolisms and the quantity of soil-inhabiting microorganisms can affect the soil physiochemical properties, and plays an impor tant role in the formation and nutrition cycle of soil.
The interplay of aggression and psychopathy in a correctional treatment setting

Field: Psychology (Social Sciences)

Introduction Aggression is a relevant risk factor for criminal behavior. Psychopathy is known to correlate with a higher risk for violent offenses and research suggests that successful therapy of psychopathy is complicated. Objectives Our goal was to explore the overlap between psychopathy and aggression and the specific influence of psychopathic traits on change in aggression during correctional therapy. Methods A pre-post-study rating psychopathy and aggression in men imprisoned for sexual and non-sexual violent offenses aged between 20 and 67 (M=37.6, SD 11.6) was conducted. The participants filled out standardized pre- and post-treatment ratings after admission and after an average of 16 months (n=144 for pre-rating, n=89 for post-rating). Psychopathy was measured via the PCL-R and aggression with the BDHI (Buss-Durkee Hostility Inventory). We calculated two-tailed Pearson correlations for BDHI Pre-, Post-, and Change Scores and the PCL-R. Further, the BDHI pre-post-differences were compared using independent t-Tests, effect sizes were calculated using Cohen’s d (small, medium, and large effect sizes are d = .20, .50, and .80). Also, unpaired t-tests were carried out to compare between participants with lower and higher PCL-R sum scores (median split, mdn= 16.8, M=16.8, SD=7.0). Results Psychopathy facets 3 and 4 (lifestyle, antisocial) and the sum score correlate significantly with the pre-, and post-BDHI total score and the subscale direct hostility but not with indirect hostility. Regarding BDHI change scores, only the interpersonal facet of PCL-R correlated significantly with direct hostility and the total BDHI score. In the whole population, a significant reduction of the BDHI was only found in the subscale indirect hostility (p=.015, cohens d= .26). In the subgroup of individuals with lower PCL-R (<16.8) showed a reduction of indirect hostility (p<.001, cohens d= .50) and the total BDHI score (p=.003, cohens d=.42). Interestingly, in the group with higher PCL-R scores no significant reduction of self-assessed hostility via BDHI was observable during therapy. Conclusions We identified a significant correlation between psychopathy and aggression, especially regarding facets three, four, and the sum score. Only the interpersonal facet correlated with the change in aggression during treatment in prison. In the group with higher psychopathic traits, no change in aggression was achievable during therapy. Thus, in the aspect of aggression and hostility, our data suggest that higher psychopathic traits may be viewed as a complicating factor for successful therapy. Disclosure of Interest None Declared
Succession of an Iowa sand prairie into an adjoining old-field

Field: Agricultural and Biological Sciences (Life Sciences)

Native plant succession studies were conducted in 2000 and 2001 at the Cedar Hills Sand Prairie northwest of Cedar Falls, IA. The study site consisted of a remnant sand prairie with an adjoining old-field that had been undergoing secondary succession since the mid-1970s. Vegetation was sampled over a 100 m transect of the remnant prairie and a 200 m transect of the old-field. The transect was sub-divided into 50 m subsites to examine progression of native species into the old-field. To analyze changes in vegetation, the similarity of the sub-sites were compared for percent canopy cover and number of species for the following categories: overall total, natives, native forbs, native grasses, sedges and rushes, non-natives, non-native forbs and non-native grasses. Additional studies examined the seed rain and seed bank.\nThe old-field vegetation of the sub-site adjacent to the remnant was most similar to the remnant and similarity decreased as distance increased. Between 50 and 150 m north of the remnant, native canopy cover diminished although the number of native species remained similar to the prairie. Apparently, this is a transition zone where native species are becoming established, but remain less prominent. Beyond this point, the vegetation in the most distant sub-site resembled a typical old-field. The number of species dropped 2 1//2 to 3 1/2 times less than the other areas of the study. Non-native species accounted for 98.5% of the canopy cover and the number of species was 2 1/2 to 3 times less than the other sites. Additionally, only one native grass was present while four to six native grass species were present in other sub-sites.\nFifty species and 2086 seeds from the seed rain were compared to vegetation surrounding each seed trap to determine species movement. A low percentage of the species and seeds in the seed traps could have originated from the nearby vegetation. Apparently seeds are moving further than expected.\nHalf the seed bank species were not present in the sampled vegetation, including several native species. Native grasses, common in the vegetation and seed rain, were scarce in the seed bank. Sedges and rushes, scarce in the vegetation and seed rain, were prominent in the seed bank.\nSuccession is an important field of study to determine what species are moving, where they are moving to and if they are becoming part of the vegetation. Over one quarter of the studies species were not present in the vegetation, signifying potential future changes in the existing vegetation.\nSecondary succession of prairie vegetation from the sand prairie remnant into the adjoining old field is proceeding slowly. Twenty-five years after the initiation of succession, the vegetation of the proximal portion of the old-field is similar to that of the adjoining remnant prairie. However, the most distant sample site of the old-field still resembles a typical abandoned agricultural field although intermediate sites are in transition to native prairie.
Solanum tuberosum L. subsp. tuberosum, KKS 10226

Field: Agricultural and Biological Sciences (Life Sciences)

PGRFA accession of IPK Gatersleben Plant Genetic Resource Taxon: Solanum tuberosum L. subsp. tuberosum Accession number: KKS 10226 Conserved by: DEU159 Acquisition: 1988 Origin country: RUS Biological status: Advanced/improved cultivar MLS status: Included AEGIS status: Not included Historic: No