Pharmaceutical Residues in Freshwater : Hazards and Policy Responses This report calls for a better understanding of the effects of pharmaceutical residues in the environment greater international collaboration and accountability distribution and policy actions to prevent and remedy emerging concerns. Laboratory and field tests show traces of oral contraceptives causing the feminisation of fish and amphibians and residues of psychiatric drugs altering fish behaviour. Antimicrobial resistance linked to the overuse of antibiotics has rapidly escalated into a global health crisis. Unless adequate measures are taken to manage the risks pharmaceutical residues will increasingly be released into the environment as ageing populations advances in healthcare and intensification of meat and fish production spur the demand for pharmaceuticals worldwide. The report outlines a collective life cycle approach to managing pharmaceuticals in the environment. A policy mix of source directed use orientated and end of pipe measures involving several policy sectors can help to improve health and protect the environment.