Chemical biology of glycoproteins Cover; Chemical Biology of Glycoproteins; Preface; Dedication; Contents; Chapter 1 Introduction: General Aspects of the Chemical Biology of Glycoproteins; 1.1 Introduction; 1.1.1 Complexity of Protein Glycosylation; 1.1.2 Strategies and Methods to Study Protein Glycosylation; 1.2 Chemical Biology of Glycoproteins; 1.2.1 Types of Protein Glycosylation; 1.2.2 Biosynthesis of Glycoproteins; 1.2.3 Structural and Functional Consequences of Protein Glycosylation; 1.2.4 Methods to Prepare Homogeneous Glycopeptides and Glycoproteins; 1.2.5 Chemical Glycobiology and Applications; 1.3 Conclusion Glycans play a vital role in modulating protein structure and function from involvement in protein folding solubility and stability to regulation of tissue distribution recognition specificity and biological activity. They can act as both positive and negative regulators of protein function providing an additional level of control with respect to genetic and environmental conditions.Due to the complexity of glycosylated protein forms elucidating structural and functional information has been challenging task for researchers but recent development of chemical biology based tools and techniques is bridging these knowledge gaps. This book provides a thorough review of the current state of glycoprotein chemical biology describing the development and application of glycoprotein and glycan synthesis technologies for understanding and manipulating protein glycosylation