MR Imaging in White Matter Diseases of the Brain and Spinal Cord In recent decades the use of neuroimaging techniques has resulted in outstanding progress in the diagnosis and management of neurological diseases and this is particularly true of those diseases that affect the white matter of the brain and spinal cord. This book written by internationally acclaimed experts comprises a series of comprehensive and up to date reviews on the use of MR imaging in these major neurological conditions. The diverse available MR techniques such as magnetization transfer MRI diffusion weighted MRI MR spectroscopy functional MRI cell specific MRI perfusion MRI and microscopic imaging with ultra high field MRI offer an extraordinarily powerful means of gaining fundamental in vivo insights into disease processes. The strengths and weaknesses of all these techniques in the study of multiple sclerosis and other relevant diseases are extensively considered. After an introductory section on neuroimaging technology subsequent sections address disorders of myelination demyelinating diseases immune mediated disorders and white matter disorders related to aging and other conditions. This book provides a valuable summary of the state of the art in the field and defines important areas for future research.