Carbohydrate based vaccines : from concept to clinic Glycoconjugate vaccines : the clinical journey Immunological mechanisms of glycoconjugate vaccines Design and development of glycoconjugate vaccines Manufacturing considerations for glycoconjugate vaccines Multivalent meningococcal conjugate vaccines : chemical conjugation strategies used for the preparation of vaccines licensed or in clinical trials The role of molecular modeling in predicting carbohydrate antigen conformation and understanding vaccine immunogenicity Advances in synthetic approaches towards glycoantigens Formulation development of glycoconjugate vaccines for low and middle income countries Pre clinical assessment of glycoconjugate vaccines Campylobacter jejuni capsule polysaccharide conjugate vaccine Chemistry manufacturing control and licensure for carbohydrate based vaccines Lessons learned and future challenges in the design and manufacture of glycoconjugate vaccines