Acids and bases : solvent effects on acid base strength Acids and bases are ubiquitous in chemistry. Our understanding of them however is dominated by their behaviour in water. Transfer to non aqueous solvents leads to profound changes in acid base strengths and to the rates and equilibria of many processes: for example synthetic reactions involving acids bases and nucleophiles; isolation of pharmaceutical actives through salt formation; formation of zwitter ions in amino acids; and chromatographic separation of substrates. This book seeks to enhance our understanding of acids and bases by reviewing and analysing their behaviour in non aqueous solvents. The behaviour is related where possible to that in water but correlations and contrasts between solvents are also presented. Fundamental background material is provided in the initial chapters: quantitative aspects of acid base equilibria including definitions and relationships between solution pH and species distribution; the influence of molecular structure on acid strengths; and acidity in aqueous solution.