Stemming the Superbug Tide : Just A Few Dollars More Antimicrobial resistance (AMR) is a large and growing problem with the potential for enormous health and economic consequences globally. As such AMR has become a central issue at the top of the public health agenda of OECD countries and beyond. In this report OECD used advanced techniques including machine learning ensemble modelling and a microsimulation model to provide support for policy action in the human health sector. AMR rates are high and are projected to grow further particularly for second and third line antibiotics and if no effective action is taken this is forecasted to produce a significant health and economic burden in OECD and EU28 countries. This burden can be addressed by implementing effective public health initiatives. This report reviews policies currently in place in high income countries and identifies a set of ‘best buys’ to tackle AMR that if scaled up at the national level would provide an affordable and cost effective instrument in the fight against AMR.