Development of synthetic strategies towards libraries of heterocyclic and bicyclic inhibitors of Cdc25A & development of solid phase synthesis of cyclic peptides Cdc25A Hantzsch pyrrole synthesis Hantzsch thiazole synthesis Paar Knorr pyrrole synthesis 1 3 dipolar cycloaddition native chemical ligation (NCL) cysteine Fmoc solid phase peptide synthesis (Fmoc SPPS) latent thioester linker cyclization. Hantzsch Pyrrol Synthese Hantzsch Thioazol Synthese Paal Knorr Pyrrol Synthese 1 3 dipolare Cycloaddition Cystein Fmoc Festphasenpeptidsynthese latente Thioester Linker Cyclisierung