Characterization of local respiratory irritation and inflammation after acute exposure to biological and chemical substances in PCLS Precision cut lung slices (PCLS) chronic obstructive lung disease (COPD) acute lung injury acute respiratory distress syndrome (ARDS) cytokine toxicity. Präzisionslungenschnitte chronisch obstruktive Lungenerkrankung akute Lungenschädigung akutes Lungenversagen Zytokine Toxizität