Neuroendocrine and gene based markers to evaluate the welfare challenges of the salmonid Coregonus maraena This dissertation aimed at obtaining a range of indicators to evaluate the welfare status of C. maraena when confronted with aquaculture related stressors. To this end the analysis of gene expression in organs and tissues was combined with in vivo and in vitro experiments to obtain a picture of relevant markers and their response to stressors. Overall the present work provides an extended panel of markers to better understand how C. maraena responds to a challenging environment.<eng>