Optimization and data analysis in biomedical informatics This volume covers some of the topics that are related to the rapidly growing field of biomedical informatics. In June 11 12 2010 a workshop entitled Optimization and Data Analysis in Biomedical Informatics was organized at The Fields Institute. Following this event invited contributions were gathered based on the talks presented at the workshop and additional invited chapters were solicited from leading experts. In this publication the authors share their expertise in the form of state of the art research and review chapters bringing together researchers from different disciplines and emphasizing the value of mathematical methods in the areas of clinical sciences