Randomization bootstrap and monte carlo methods in biology Modern computer intensive statistical methods play a key role in solving many problems across a wide range of scientific disciplines. Like its bestselling predecessors the fourth edition of Randomization Bootstrap and Monte Carlo Methods in Biology illustrates a large number of statistical methods with an emphasis on biological applications. The focus is now on the use of randomization bootstrapping and Monte Carlo methods in constructing confidence intervals and doing tests of significance. It provides comprehensive coverage of computer intensive applications with datasets available online