Single molecule science : from super resolution microscopy to DNA mapping and diagnostics Single Molecule Science (SMS) has emerged from developing using and combining technologies such as super resolution microscopy atomic force microscopy and optical and magnetic tweezers alongside sophisticated computational and modelling techniques. This comprehensive edited volume brings together authoritative overviews of these methods from a biological perspective and highlights how they can be used to observe and track individual molecules and monitor molecular interactions in living cells. Pioneers in this fast moving field cover topics such as single molecule optical maps nanomachines and protein folding and dynamics. A particular emphasis is also given to mapping DNA molecules for diagnostic purposes and the study of gene expression. With numerous illustrations this book reveals how SMS has presented us with a new way of understanding life processes. A must have for researchers and graduate students as well as those working in industry primarily in the areas of biophysics biological imaging genomics and structural biology