Big and Complex Data Analysis : Methodologies and Applications This volume conveys some of the surprises puzzles and success stories in high dimensional and complex data analysis and related fields. Its peer reviewed contributions showcase recent advances in variable selection estimation and prediction strategies for a host of useful models as well as essential new developments in the field. The continued and rapid advancement of modern technology now allows scientists to collect data of increasingly unprecedented size and complexity. Examples include epigenomic data genomic data proteomic data high resolution image data high frequency financial data functional and longitudinal data and network data. Simultaneous variable selection and estimation is one of the key statistical problems involved in analyzing such big and complex data. The purpose of this book is to stimulate research and foster interaction between researchers in the area of high dimensional data analysis. More concretely its goals are to: 1) highlight and expand the breadth of existing methods in big data and high dimensional data analysis and their potential for the advancement of both the mathematical and statistical sciences; 2) identify important directions for future research in the theory of regularization methods in algorithmic development and in methodologies for different application areas; and 3) facilitate collaboration between theoretical and subject specific researchers Preface Introduction Unsupervised Bump Hunting Using Principal Components Statistical Process Control Charts as a Tool for Analyzing Big Data Empirical Likelihood Test for High Dimensional Generalized Linear Models Identifying gene environment interactions associated with prognosis using penalized quantile regression A Computationally Efficient Approach for Modeling Complex and Big Survival Data Regularization after marginal learning for ultra high dimensional regression models Tests of concentration for low dimensional and high dimensional directional data Random Projections For Large Scale Regression How Different are Estimated Genetic Networks of Cancer Subtypes Analysis of correlated data with error prone response under generalized linear mixed models High Dimensional Classification for Brain Decoding Optimal shrinkage estimation in heteroscedastic hierarchical linear models Bias reduced moment estimators of Population Spectral Distribution and their applications Testing in the Presence of Nuisance Parameters: Some Comments on Tests Post Model Selection and Random Critical Values A Mixture of Variance Gamma Factor Analyzers Fast Community Detection in Complex Networks with a K Depths Classifier