Current developments in biotechnology and bioengineering : bioprocesses bioreactors and controls 2.4.1 Statistical Methods2.4.1.1 Two Factorial Design; 2.4.1.2 Plackett Burman Design; 2.4.1.3 Response Surface Methodology; 2.4.1.4 Mixture Design; 2.4.1.5 Uniform Design; 2.4.1.6 Taguchi Design; 2.4.2 Computer Modeling and Simulation; 2.4.3 Engineering Tools and Bioreactor Design; 2.4.3.1 Solid State Bioreactor; 2.4.3.1.1 GROUP I REACTOR; 2.4.3.1.2 GROUP II REACTOR; 2.4.3.1.3 GROUP III REACTOR; 2.4.3.1.4 GROUP IV REACTOR; 2.4.3.2 Fed Batch Reactor; 2.4.3.3 Stirred Tank Reactor; 2.5 Conclusion; References; 3 Microbial Bioprocesses; 3.1 Introduction; 3.2 Primary Metabolism 1.3.1 Processing of Lignocellulosic Materials Cellulose Hydrolysis and Saccharification1.3.2 Bioprocessing of Lignocellulose Derived Sugars; 1.3.3 Biorefinery of Lignocellulosic Materials Using Thermochemical Platform; 1.4 Third Generation Biorefineries: Biorefineries of Microalgae; 1.5 Fuel and Chemical Production Through Biological Conversions; 1.6 Conclusions and Future Prospects; References; 2 Design and Types of Bioprocesses; 2.1 Introduction; 2.2 Bioprocesses; 2.3 Types of Bioprocesses; 2.3.1 Batch; 2.3.2 Fed Batch; 2.3.3 Continuous; 2.4 Tools and Techniques Front Cover; Current Developments in Biotechnology and Bioengineering; Current Developments in Biotechnology and Bioengineering: Bioprocesses Bioreactors and Controls; Copyright; Contents; List of Contributors; About the Editors; Preface; 1 Industrial Bioprocesses; 1 Industrial Bioprocesses and the Biorefinery Concept; 1.1 Introduction; 1.2 First Generation Biorefineries; 1.2.1 Corn Biorefineries; 1.2.2 Soybean Biorefineries; 1.2.3 Sugarcane Biorefineries; 1.3 Second Generation Biorefineries: Biorefineries of Lignocellulosic Materials 3.3 Secondary Metabolism3.4 Production Processes of Primary Metabolites; 3.4.1 Microbial Biomass Production Processes; 3.4.1.1 Production of Bakers Yeast; 3.4.1.2 Single Cell Protein; 3.4.2 Organic Acids; 3.4.2.1 Citric Acid; 3.4.2.2 Gluconic Acid; 3.4.2.3 Lactic Acid; 3.4.2.4 Itaconic Acid; 3.4.3 Enzymes; 3.4.4 Amino Acids; 3.4.4.1 l Glutamic Acid; 3.4.4.2 l Lysine; 3.4.5 Extracellular Polysaccharides; 3.4.6 Other Industrial Chemicals and Fuels; 3.5 Production Processes of Secondary Metabolites; 3.5.1 Antibiotics; 3.5.1.1 Penicillin; 3.5.1.2 Cephalosporins; 3.6 Future Perspectives