Chemical toxicity prediction : category formation and read across The aim of this book is to provide the scientific background to using the formation of chemical categories or groups of molecules to allow for read across i.e. the prediction of toxicity from chemical structure. It covers the scientific basis for this approach to toxicity prediction including the methods to group compounds (structural analogues and or similarity mechanism of action) and the tools to achieve this. The approaches to perform read across within a chemical category are also described. The book will provide concise practical guidance for those wishing to apply these methods (in risk hazard assessment) and will be illustrated with case studies. This is the first book that addresses the concept of category formation and read across for toxicity prediction specifically. This topic has really taken off in the past few years due to concerns over dealing with the REACH legislation and also due to the availability of the OECD (Q)SAR Toolbox. Much (lengthy and complex) guidance is available on category formation e.g. from the OECD and to a lesser extent the European Chemicals Agency but there is no one single source of information that covers all techniques in a concise user friendly format