Risikominderung in der Wertschöpfungskette als Innovationsprozess : Rahmenbedingungen und Akteure der Gefahrstoffsubstitution ; Endbericht des BMBF Projektes Gestaltungsoptionen für handlungsfähige Innovationssysteme zur erfolgreichen Substitution gefährlicher Stoffe Hazardous substances substitution chemical substitute occupational safety and health environmental protection consumer protection innovation system capability to innovate innovation direction risk assessment risk management sypply chain precautionary principle quality management system guiding principles inherent safety sustainable chemistry green chemistry closed loop economy persistence chemicals regulation REACH cleaning of metal surfaces plasticizers mineral fibres cooling lubricants concrete separation agents automotive series coatings textile auxiliary agents packaging printing low chromate cement stripping agents decorative paints