Biomedical imaging : the chemistry of labels probes and contrast agents Medical imaging : overview and the importance of contrast John C. Waterton Biomedical imaging : advances in radiotracer and radiopharmaceutical chemistry Robert N. Hanson Recent developments in PET and SPECT radioligands for CNS imaging David Alagille Ronald M. Baldwin and Gilles D. Tamagnan Design and synthesis of radiopharmaceuticals for SPECT imaging David Hubers and Peter J.H. Scott MRI contrast agents : synthesis applications and perspectives Pier Lucio Anelli Luciano Lattuada and Massimo Visigalli The future of biomedical imaging : synthesis and chemical properties of the DTPA and DOTA derivative ligands and their complexes E. Brücher Zs. Baranyai and Gy. Tircsó MRI contrast agents based on metallofullerenes Chun Ying Shu and Chun Ru Wang Application of magnetic resonance imaging (MRI) to radiotherapy Jenghwa Chang ... [et al.] Autoradiography in pharmaceutical discovery development Eric G. Solon In vivo fluorescence optical and multi modal imaging in pharmacological research : from chemistry to therapy monitoring Rainer Kneuer ... [et al.] Fluorescence lifetime imaging applied to microviscosity mapping and fluorescence modification studies in cells Klaus Suhling ... [et al.] Design and use of contrast agents for ultrasound imaging Fabian Kiessling Georg Schmitz and Jessica Gätjens Imaging as a CNS biomarker Ricahrd Hargreaves Lino Becerra and David Borsook Magnetic resonance imaging in drug development Jin Xie and Xiaoyuan Chen MRI in practical drug discovery K.K. Changani M.V. Fachiri and S. Hotee Peering into the future of MRI contrast agents Darren K. MacFarland The focus of this new book is for medicinal chemists on the chemical agents that have been used or might be required in the future and the methods of synthesis for inserting the reporter groups. Medicinal chemists need to know the critical issues involved in using such chemical agents with regard to the biological applications for instance what properties are needed chemically and why The topics covered in the book are: PET SPECT contrast agents radioimaging radionuclide conjugates receptor mapping small animal imaging (eg. WBAR whole body autoradiography); photoinduced labelling as well as chapters on the physical techniques used including: NMR mass spectrometry and Xray. A key reference for academics postgraduates researchers industrialists and professionals working in or joining this field