Heart Rate Variability Analysis with the R package RHRV This book introduces readers to the basic concepts of Heart Rate Variability (HRV) and its most important analysis algorithms using a hands on approach based on the open source RHRV software. HRV refers to the variation over time of the intervals between consecutive heartbeats. Despite its apparent simplicity HRV is one of the most important markers of the autonomic nervous system activity and it has been recognized as a useful predictor of several pathologies. The book discusses all the basic HRV topics including the physiological contributions to HRV clinical applications HRV data acquisition HRV data manipulation and HRV analysis using time domain frequency domain time frequency nonlinear and fractal techniques. Detailed examples based on real data sets are provided throughout the book to illustrate the algorithms and discuss the physiological implications of the results. Offering a comprehensive guide to analyzing beat information with RHRV the book is intended for masters and Ph.D. students in various disciplines such as biomedical engineering human and veterinary medicine biology and pharmacy as well as researchers conducting heart rate variability analyses on both human and animal data Foreword Preface 1 Introduction to Heart Rate Variability 2 Loading Plotting and Filtering RR Intervals 3 Time Domain Analysis 4 Frequency Domain Analysis 5 Nonlinear and Fractal Analysis 6 Comparing HRV Variability across Different Segments of a Recording 7 Putting it All Together a Practical Example A Installing RHRV B How do I Get a Series of RR Intervals from a Clinical Biological Experiment