Laser Driven Particle Acceleration Towards Radiobiology and Medicine From the Contents: Part I Laser driven particle acceleration: From experiments to devices Ultra intense lasers and particle acceleration: past present and future Part II Biophysical studies with laser driven particle sources Part III Synchrotron ion accelerator and microbeam Synchrotron source: dosimetry and pre clinical trials. This book deals with the new method of laser driven acceleration for application to radiation biophysics and medicine. It provides multidisciplinary contributions from world leading scientist in order to assess the state of the art of innovative tools for radiation biology research and medical applications of ionizing radiation. The book contains insightful contributions on highly topical aspects of spatio temporal radiation biophysics evolving over several orders of magnitude typically from femtosecond and sub micrometer scales. Particular attention is devoted to the emerging technology of laser driven particle accelerators and their applicatio to spatio temporal radiation biology and medical physics customization of non conventional and selective radiotherapy and optimized radioprotection protocols.