Biomimetic bioresponsive and bioactive materials : an introduction to integrating materials with tissues This comprehensive introduction to biomaterials discusses how materials are selected designed and modified for integration with living tissue. Biomaterials have applications in tissue engineering medical devices orthopedics and other areas. This guide examines the physico chemical properties of widely used biomaterials and cites examples of their uses in different clinical applications. Topics covered include soft and hard tissue replacement; biointeractive metals polymers and ceramics; and in vitro in vivo and ex vivo biocompatibility tests and clinical trials. This text is for students as well as professionals new to the field