After being in hospital in March 2002 with kidney trouble, he underwent a heart transplant at Papworth Hospital, Cambridge in 2003. He recovered fully. Large was hospitalised for weeks in late 2013 after tripping over a road sign near his Portishead, Somerset home.
Large died on 2 April 2020 of COVID-19 at a hospital in Bristol at the age of 78.
Cliff Michelmore
Arthur Clifford "Cliff" Michelmore (11 December 1919 – 16 March 2016) was an English television presenter and producer. He was best known for the BBC television programme "Tonight", which he presented from 1957 to 1965.
Michelmore died on 16 March 2016 in a hospital in Hampshire, England at the age of 96.
Martin Crowe
Martin David Crowe (22 September 1962 – 3 March 2016) was a New Zealand cricketer, commentator and author. He was a Wisden Cricketer of the Year in 1985, and was thought as one of the "best young batsmen in the world". A right-handed batsman, Crowe represented New Zealand from the early 1980s until his retirement in 1996. His cousin is actor Russell Crowe.
In 2012, Crowe announced that he is suffering from lymphoma. In 2013, he said that the cancer has disappeared. In 2014 however, Crowe announced that the lymphoma had returned and said that his chances of survival beyond a year were less than 5% and also of his wish to see the 2015 Cricket World Cup in February and March 2015.
Crowe died from complications of lymphoma in Auckland, New Zealand on 3 March 2016 at the age of 53.
Ken Kercheval
Ken Kercheval (July 15, 1935 – April 21, 2019) was an American actor. He was best known for his role as Cliff Barnes on the 1980s television series "Dallas" and its 2012 revival.
Kercheval died of pneumonia in Clinton, Indiana on April 21, 2019 at the age of 83.
Erwin Neher
Erwin Neher (; ; born 20 March 1944) is a German biophysicist. His works focused on cell physiology. In 1991, with Bert Sakmann, he won the Nobel Prize in Physiology or Medicine for "their discoveries concerning the function of single ion channels in cells".
Bert Sakmann
Bert Sakmann (born 12 June 1942) is a German cell physiologist. He won the Nobel Prize in Physiology or Medicine with Erwin Neher in 1991 for their work on "the function of single ion channels in cells," and the invention of the patch clamp.
Sakmann was Professor at Heidelberg University and is an Emeritus Scientific Member of the Max Planck Institute for Medical Research in Heidelberg, Germany. He has also worked with research group at the Max Planck Institute of Neurobiology.
Sakmann was born in Stuttgart.
Edmond H. Fischer
Edmond Henri Fischer (born April 6, 1920) is a Swiss-born American biochemist. He and his partner Edwin G. Krebs were awarded the Nobel Prize in Physiology or Medicine in 1992 for their works on phosphorylation works as a switch to activate proteins and regulate various cellular processes. From 2007 until 2014, he was the Honorary President of the World Cultural Council.
Peter Mansfield
Sir Peter Mansfield FRS, (9 October 1933 – 8 February 2017) was an English physicist. He was awarded the 2003 Nobel Prize in Physiology or Medicine. He shared with Paul Lauterbur. He was known for his discoveries concerning Magnetic Resonance Imaging (MRI). Mansfield was a professor at the University of Nottingham.
Mansfield was born in Lambeth, London. He studied at Queen Mary College, London. Mansfield graduated with a BSc from Queen Mary's in 1959.
Mansfield died in Nottingham, England on 8 February 2017, aged 83.
Thomas C. Südhof
Thomas Christian Südhof (born December 22, 1955), is a German-American biochemist. He is known for his study of synaptic transmission.
Südhof, James Rothman and Randy Schekman won the 2013 Nobel Prize in Physiology or Medicine for their work on vesicle trafficking.
John O'Keefe
John O'Keefe, FRS FMedSci (born November 18, 1939) is an American-British neuroscientist. He is a professor at the Sainsbury Wellcome Centre for Neural Circuits and Behaviour and the Research Department of Cell and Developmental Biology at University College London. He is one of the most notable alumni of City College of New York.
O'Keefe is known for his discovery of place cells in the hippocampus. He discovered that they show a kind of coding for places. This is a positioning system, an “inner GPS” in the brain that makes it possible to orient ourselves in space.
In 2014, he received the Kavli Prize in Neuroscience "for the discovery of specialized brain networks for memory and cognition", together with Brenda Milner and Marcus Raichle. He shared the one-half of the Nobel Prize in Physiology or Medicine in 2014 with May-Britt Moser and Edvard Moser, who shared the other half jointly.
O’Keefe and his student Jonathan Dostrovsky discovered place cells by systematically analyzing the environmental factors influencing the firing properties of individual hippocampal neurons.
His many publications on place cells have been highly cited. In addition, he published an influential book with Lynn Nadel, proposing the functional role of the hippocampus as a cognitive map for spatial memory function. In extensions of his work, place cells have been analyzed experimentally or simulated in models in hundreds of papers.
Wilfrid Laurier
Sir Henri Charles Wilfrid Laurier (20 November 1841 – 17 February 1919), known as Wilfrid Laurier (; ), was the seventh Prime Minister of Canada from 11 July 1896 to 6 October 1911.
Robert Borden
Sir Robert Laird Borden (June 26, 1854 – June 10, 1937) was a Canadian lawyer and politician. He served as the eighth Prime Minister of Canada from October 10, 1911, to July 10, 1920. He was the third Nova Scotian to hold this office.
After retiring from public life, he served as the chancellor of Queen's University. His portrait appears on Canadian $100 bills produced since 1976.
Arthur Meighen
Arthur Meighen (; 16 June 1874 – 5 August 1960) was a Canadian lawyer and politician who served as the ninth prime minister of Canada, in office from July 1920 to December 1921 and again from June to September 1926.
William Lyon Mackenzie King
William Lyon Mackenzie King, PC, OM, CMG (December 17, 1874 – July 22, 1950), also commonly known as Mackenzie King, was the dominant Canadian political leader from the 1920s through the 1940s.
He served as the tenth Prime Minister of Canada from December 29, 1921 to June 28, 1926; from September 25, 1926 to August 7, 1930; and from October 23, 1935 to November 15, 1948. A Liberal with 22 years in office, he was the longest-serving Prime Minister in Canadian history.
King died on July 22, 1950, at Kingsmere from pneumonia, aged 75. He is buried in Mount Pleasant Cemetery, Toronto.
R. B. Bennett
Richard Bedford Bennett, 1st Viscount Bennett, (3 July 1870 – 26 June 1947), was a Canadian lawyer, businessman, and politician. He was the 11th prime minister of Canada from 1930 to 1935.
Louis St. Laurent
Louis Stephen St. Laurent ("Saint-Laurent" or "St-Laurent" in French, baptized Louis-Étienne St-Laurent; 1 February 1882 – 25 July 1973) was the 12th prime minister of Canada, from 15 November 1948 to 21 June 1957.
John Diefenbaker
John George Diefenbaker (September 18, 1895 – August 16, 1979) was the 13th Prime Minister of Canada from June 21, 1957 to April 22, 1963.
Diefenbaker was known for his passing laws meant to reduce racial discrimination.
Pope Boniface VI
Pope Boniface VI (; 806 – April 896) was the bishop of Rome. He was Pope of the Papal States in April 896. He was from Rome.
His election came about as a result of riots soon after the death of Pope Formosus. After a pontificate of fifteen days, he is said by some to have died of the gout.
John IX, in 898, said that his election was null and void.
Pope Clement VI
Pope Clement VI (; 1291 – 6 December 1352), born Pierre Roger, was Pope of the Catholic Church from 7 May 1342 to his death in 1352. He was the fourth Avignon pope.
Clement reigned during the Black Death (1348–1350), during which he said all who died of the plague would not go to hell.