Many electronic music artists (music made with computers or other electronic instruments) use computer software to make new music parts, called "tracks". The music parts contain notes which are arranged with a computer program called a sequencer. The actual notes are played by instruments, usually synthesizers, a type of electronic musical instrument that makes sounds by changing the shape of a sound wave. It is also possible for a remixer to use a drum sample kit, a set of sounds of fake or real drums recorded for use on a computer.
Rendering
When the remixer has a proper sequence in the sequencer, he or she can then render the audio part, or track. Rendering requires the sequencer to talk to the musical instrument, usually by computer software or a computer-to-computer talking language called MIDI to an actual electronic keyboard. The sequencer tells the instrument which note to play, and then the instrument plays the note. The sequencer writes this note to a music file on the computer.
A mashup is a remixing style in which a remixer takes two songs and mixes them with each other in a clever way to create a new song. Usually, it is the vocal of the song they want to remix with the other musical parts of an older song.
Instead of using a sequencer and a musical instrument, a remixer can use either record-playing turntables or a computer with an audio sequence editor, for example the program named ACID music. He or she also needs an audio editor, a computer program that allows someone to record sounds into a computer as well as cut them down to smaller bits.
Usually, a small bit of the old song is "cut" in an audio editor into a loop, a piece of music that when played on repeat does not have any skips or musical pauses. This loop is usually called a "sample" in the world of remixing. This sample is then looped (played over and over) in a sequence to create a new sound. The remixer then mixes the vocal of another song over that loop.
It is also possible that a mashup style remixer will take the entire musical part of one song without its vocal - called an instrumental - and take a vocal from another song without the non-voice part - called an acapella, and put them together to create one song.
H. P. Lovecraft
Howard Phillips Lovecraft (August 20, 1890 – March 15, 1937) was an American author of fantasy, horror and science fiction.
He wrote many scary short stories. These often were about odd creatures that Lovecraft made up by himself or with his friends, including August Derleth, who wrote mysteries. The creatures did not really care about human people at all, so they were not out to hurt people, but if they did, they did not care. They looked at us like we would be ants. Their behaviour, attitude and look also tended to make people go crazy.
Lovecraft's stories were inspiration for lots of other authors.The spirit of his works, presenting a world that does not care, is present in many works of fiction.
Lovecraft was born in Providence, Rhode Island on August 20, 1890. He was the only child in the family. He died of small intestine cancer there.
Hormone
Hormones are the chemical messengers of the endocrine system. Hormones are the signals which adjust the body's internal working, together with the nervous system. Every multicellular organism has hormones. The cells which react to a given hormone have special receptors for that hormone. When a hormone attaches to the receptor protein a mechanism for signalling is started. The cell or tissue that gets the message is called the 'target'. Hormones only act on cells which have the right receptors.
Many different kinds of cells can send a message. There are some cells whose main job is to make hormones. When many of these cells are together, they are called a gland. Glands are groups of cells that make something and release it (put it outside the cell). Many glands make hormones.
"Endocrine" means secreting directly into the blood. Most internal secretions are from endocrine glands. The opposite word is "exocrine", which means secreting through a duct or tube. Some hormones are produced by exocrine glands, and some exocrine secretions release outside the body. Sweat glands and salivary glands are examples of exocrine glands whose products are released outside the body.
The first discovery of a hormone was made in 1902. The hormone was secretin. The word 'hormone' was first used in 1905.
Hormones do many things. They regulate metabolism. Metabolism is the chemical and energy reactions that happen in a living thing. Hormones cause the growth and death of cells and of whole organisms. Hormones also start and control sexual development. For example, the hormones estrogen and progesterone make girls go through puberty. Hormones help keep homeostasis in an organism. Homeostasis means to keep a constant state inside the body like temperature, amount of water and salts, and amount of sugar. Hormones released by one gland can also tell other glands to make different hormones.
There are four types of hormones in most vertebrates. They are grouped by the chemicals from which they are made.
In biology regulation means to control something. So regulating hormones means controlling how much hormones are made and released from cells.
Hormone regulation is mostly done by negative feedback. In negative feedback, a hormone causes an effect. The cells that make the hormone detect this effect and its production ceases.
A good example of negative feedback is with the hormone insulin. Insulin is produced by the pancreas. Insulin is released by the pancreas in response to consumption of glucose. The amount of glucose in the blood rises, and the pancreas detects the increase. It then secretes insulin into the blood. Insulin increases glucose uptake in target cells. Some glucose is used by the cells but some is also converted to and stored in the form of glycogen. Glucose uptake by cells decreases blood glucose levels. This decrease is detected by the pancreas and in response, it stops secreting insulin in to the bloodstream. As insulin levels in the blood decrease, so does glucose uptake by cells.
This negative feedback therefore helps to maintain normal blood glucose levels and prevents extreme changes.
There are three main types of hormones. Steroid hormones are non-polar and do not need a receptor. The second type is peptide hormones. The third is Tyrosine derived hormones. An example is the T3 and T4 hormones produced by the thyroid gland.
Often two hormones control the same product, one increasing and the other decreasing the target. Blood glucose is very important to an organism, and is controlled by more than one hormone. Other hormones also make the glucose level go up or down. If the glucose level gets too low, the body releases hormones that do the opposite of insulin. They do not tell the cells in the body to take up glucose from the blood. They tell the cells to put glucose back into the blood. These kind of hormones that work opposite of other hormones are called counter-regulatory hormones. Counter-regulatory hormones for insulin are glucagon and epinephrine.
Most important things in an organism are kept in homeostasis by negative feedback and counter-regulatory hormones. However a few things are controlled in different ways. One rare way is positive feedback. In negative feedback, the hormone's effect makes a gland stop making hormones. In positive feedback the opposite happens. The effect of the hormone tells the gland to make even more hormones.