Timothy Pickering (July 17, 1745 – January 29, 1829) was a politician from Massachusetts who served in a variety of roles, most notably as the third United States Secretary of State, serving in that office from 1795 to 1800 under Presidents George Washington and John Adams.
John Jay
John Jay (December 12, 1745 – May 17, 1829) was an American politician, statesman, slave owner, and diplomat. He was a Supreme Court Chief Justice and one of the Founding Fathers of the United States. Jay served in the Continental Congress and was elected President of that body. During and after the American Revolution, he was a minister (ambassador) to Spain and France, helping to fashion American foreign policy and to secure favorable peace terms from the British and French. He co-wrote the "Federalist Papers" with Alexander Hamilton and James Madison.
Jay served on the U.S. Supreme Court as the first Chief Justice of the United States from 1789 to 1795. In 1794 he negotiated the Jay Treaty with the British. A leader of the new Federalist party, Jay was governor of New York from 1795 to 1801. He was the leading opponent of slavery and the slave trade in New York. His first attempt to pass emancipation legislation failed in 1777 and failed again in 1785, but he succeeded in 1799, signing the law that eventually emancipated the slaves of New York; the last were freed before his death.
Evan Longoria
Evan Michael "Longo" Longoria is a third baseman for the San Francisco Giants. Longoria began his MLB career with the Tampa Bay Rays before being traded to the Giants in 2017. He won the 2008 American League Rookie of the Year award. In 2009, he won the Silver Slugger and Gold Glove awards for American League third basemen. Longoria once again won the Gold Glove award in 2010 and 2017.
Nucleolus
A nucleolus (plural: nucleoli) is the part of a eukaryotic cell where ribosomes are made. Seen under a microscope, the nucleolus is a dark spot inside the cell's nucleus. It is made up of dense RNA and proteins. Prokaryotic cells also have ribosomes, but they don't make as many as eukaryotes do, and there is no visible nucleotatius. There is usually more than one nucleolus in a eukaryote cell. The nucleolus is not bounded by a membrane.
The nucleolus is made at a nucleolus organizer region (NOR), which is a chromosome region around which the nucleolus forms. Inside the nucleolus ribosomes are made. Ribosomes are molecular machines that synthesizes proteins. The ribosomes are exported through the nuclear envelope to the cytoplasm, where they do their work.
Nucleoli play a role in the cell's response to stress. They also help in the assembly of signal recognition particles. Malfunction of nucleoli can be the cause of several human diseases.
Candice Bergen
Candice Bergen (born May 9, 1946) is an American actress. In 1980, she was nominated for an Academy Award for "Best Actress in a Supporting Role" for her role in "Starting Over". Bergen later acted as the title character in "Murphy Brown". (1988-98, 2018-present).
Duke Nukem 3D
Duke Nukem 3D is a first-person shooter video game. It was made by 3D Realms and sold by Apogee Software. It was first sold on January 29, 1996. "Duke Nukem 3D" is based on the main character from the platform games "Duke Nukem" and "Duke Nukem II" which were also published by Apogee. The character is voiced by Jon St. John.
In the game, players control Duke Nukem, an action hero from Earth. Players must fight invading aliens that want to take over Earth. The game is made up of 28 levels spread over three chapters. An add-on pack called "The Plutonium Pak", later added a fourth episode of 11 new levels, new enemies, and one new weapon.
The game is a first person shooter, so the player sees the game from Duke's eyes. Instead of following the character around like a third-person shooter, Duke Nukem is like being "inside" Duke, and the player can see Duke's hands and weapons on the screen. The player fights the aliens, most often by shooting at them with different guns, but Duke can also kick, and throw pipe bombs like grenades. The player must also sometimes solve puzzles to find the way through the level.
"Duke Nukem 3D" is set "sometime in the early 21st century", starting in a badly worn down Los Angeles. The game moves on to places such as lunar space stations. An alien transgenic species has invaded Earth while Duke has been fighting in space. Duke crash lands back on Earth and finds most humans are gone. Only a few women remain as slaves for the aliens. America has been turned into a wasteland, and pornography has become the only entertainment.
The levels of "Duke Nukem 3D" take the player outdoors and indoors, on the street, inside military bases, deserts, flooded cities, space stations, moon bases and Japanese villas. Levels were designed with many routes so that players can climb through air ducts, back doors and sewers to avoid enemies or find hidden secrets. This makes the levels well suited to multiplayer deathmatchs. The secret items also include (light switches to make it easier to see, water fountains and broken hydrants provide some health points) or simply provide a touch of diversion and strippers who Duke tells jokes to and sometimes they open up their clothes.
The game includes a range of weapons, some of which, even today, are still unique to the "Duke Nukem" series. They range from Duke's foot for kicking, a pistol, a "Chain gun" (similar in design to the Nordenfelt gun), pipe bombs, freeze- and shrink-rays, and laser-trip-mines.
Aside from weapons, Nukem can also find 'medkits' to heal himself whenever the player chooses. Steroids make the player move faster, as well as removing the effects of the shrink-ray. Nightvision goggles allow players to see enemies in the dark. The "HoloDuke" device projects a fake hologram of Duke that can be used to trick enemies. Protective boots allow the player to cross dangerously hot or toxic floors. For underwater scenes, scuba gear (an aqua-lung) can be used to let Duke breathe. One of the favorite items is the jetpack which allows the player to fly up in the sky, often to reach hidden weapons or extra health. Many of the secret items such as the jetpack, the scuba gear and the night vision goggles only last for a short time. Weapons also have a limited number of ammunition.
There are many monsters in the game. Some of these are aliens, others mutated humans (the LAPD has been turned into monster pigs). Similar to many first-person shooter games, Nukem encounters a large number of weaker enemies, and a small number of boss enemies (extremely powerful). Like Duke, these "boss" enemies have a wide range of weapons and equipment (some weaker enemies have jet packs).
In 1996, at the time of the game's release, Internet-based gaming was just beginning and "Duke Nukem 3D" could be played on IPX LAN or modem. "Duke Nukem 3D" players often used the IPX network utility Kali or the Total Entertainment Network (TEN) online service. Kali allowed users to join a chat room to find opponents. The Total Entertainment Network had hundreds of Duke 3D players online at any time, but players had to pay money monthly for it. The game's levels are often used as the battlegrounds for these online players, bur users are able to create their own levels ("maps"). The game also features co-operative play (co-op) which allows players to fight against the aliens instead of each other. In the "Atomic" version, a new game play mode was introduced: Duke Tag, a "capture the flag" style mode.
Ken Silverman's Build engine allowed complicated levels. The game could use slopes in the floors. It also supports upwards and downwards mouse aiming (though aiming up and down distorts the graphics due to not having perspective correction).