Every disease and gene is given a six digit number. The first digit in each number tells how the gene or disease is inherited (passed from one generation to the next).
If the initial digit is 1, the trait is autosomal dominant; if 2, autosomal recessive; if 3, X-linked. Each trait defined in this dictionary has a MIM number, the number from the 12th edition of MIM. The MIM number is printed in square brackets with or without an asterisk (asterisks indicate that the mode of inheritance is known; a number symbol (#) before an entry number means that the phenotype can be caused by mutation in any of two or more genes) as appropriate. For example, Pelizaeus-Merzbacher disease [MIM #312080] is an X-linked recessive disorder.
Range of MIM codes: method of inheritance
These codes have been used in the medical literature to provide a unified index to genetic diseases.
Valdagno
Valdagno is a comune in the province of Vicenza, in Italy
Un ballo in maschera
Un ballo in maschera (A Masked Ball) is an Italian opera in three acts. The music was written by Giuseppe Verdi. The libretto was written by Antonio Somma. It is based on Eugène Scribe's "Gustave III ou Le Bal Masqué".
The opera was first performed at the Teatro Appollo in Rome, on February 17, 1859. One of Verdi's richest middle-period works, it relates the events surrounding the assassination of King Gustav III of Sweden, but because of censorship, the story was transposed to 17th century Boston, with Gustav becoming an English governor, Richard of Warwick. Nowadays, most productions present the opera in its original Swedish setting.
Aboriginal land rights in Australia
Aboriginal land rights in Australia are the special set of rights given to Indigenous Australians to own land. There are many different types of land rights laws. They all allow the government to grant land to indigenous (native) Australians under many different conditions (terms). Land rights schemes are in place in the Northern Territory, Queensland, New South Wales, South Australia, and Victoria. Under these laws, the title to the land is normally given to a community or ethnic group, not an individual. Usually, land that has been granted in a land rights claim can not be sold, traded, or mortgaged. Grants will be normally require that the land be passed down to future generations through inheritance.
The passing of Aboriginal land rights laws in Australia was caused by many important Aboriginal protests. It was not until the 1970s, though, that there came an "organised" movement for the recognition of Aboriginal land rights.
On 1 May 1946, more than 800 Aboriginal stockmen in the Pilbara region of Western Australia went on strike. They demanded wages for their work. They were joined by other Aboriginal workers from the towns of Port Hedland and Marble Bar. The strike ended in 1949.
In 1963, the government turned part of the Yolngu people's traditional lands (in Arnhem Land) into a bauxite mine. The Yolngu started a petition (now called the Yirrkala bark petitions) to demand the rights to these lands. The petition was turned into a legal case. Mining went ahead anyway, and the legal case went on for 41 years. The Yolngu were finally made a part of the agreement between the government and the mining company in 2011.
In 1964 and 1965, students from the University of Sydney formed a group called the Student Action for Aboriginals. They travelled into New South Wales country towns to research segregation between native and non-native people. They led protests to get people to know about the issue of Aboriginal civil rights. It became known as the Freedom Ride movement. At the time, Aboriginal people were not counted in the census and their civil rights were different to white citizens. This changed in 1967, when a referendum gave Aborigines the same rights as white Australians.
The Wave Hill walk-off was in August 1966. A total of 200 Gurindji stockmen and servants at Wave Hill cattle station went on strike to demand wages and the return of some of their traditional lands. The strike went for nine years. The demand was not met, but the Gurindji stayed camped on their traditional country. They chose to break the state's law but obey their own. It raised popular support for Aboriginal land rights. Supporters in the cities rallied for the Gurindji and eventually they won title to part of their land.
In 1973, an Aboriginal Land Rights Commission was created in the Northern Territory. This royal commission said that the government should recognise Aboringal Land Rights, and gave advice for passing laws on it. Prime Minister Gough Whitlam took the advice and brought a Land Rights Bill to parliament. It was changed by the next prime minister, Malcolm Fraser, and passed by the Governor-General on 16 December 1976.
In 1976, the Territory government passed the first Aboriginal land rights law in the country. It allowed Aboriginal people in the Territory to claim rights to land that their ancestors had lived on before the arrival of white people. Groups that made claims had to show proof of their traditional (historical) association with the land. This ended up giving almost 50% of land in the Northern Territory (around ) to native groups. Before this act, there had been many "indigenous reserves" in the Northern Territory. This land was owned by the government and set aside for Aboriginal people to live on until they were assimilated into white society. When the act was put into effect, the old "reserves" were given to the Aboriginal groups living on them without them having to make a claim.
Safety Last!
Safety Last! is a 1923 silent movie. It is a romantic comedy. It stars Harold Lloyd. The image of Lloyd clutching the hands of a large clock as he dangles from the outside of a skyscraper above moving traffic is well known. The movie was very successful and critically hailed. It cemented Lloyd's status as a major figure in early movies. It is still popular with movie buffs. Lloyd performed some of his climbing stunts despite losing a thumb and forefinger in an accident while making a movie four years earlier.
Mario Manningham
Mario Cashmere Manningham (born May 25, 1986) is an American football wide receiver who currently plays for the San Francisco 49ers of the National Football League. He was drafted by the New York Giants in the third round of the 2008 NFL Draft. He played college football at Michigan.
In 2005, as a freshman, Manningham had 27 receptions for 433 yards and six touchdowns, including the game-winning catch as time expired in the game against Penn State, handing the Lions their only loss that season.
Manningham finished 2006 with a total 38 receptions 703 yards and nine touchdowns. He was named Big Ten Offensive Player of the Week two weeks in a row, first against Notre Dame and then against Wisconsin.
Manningham had a total of 72 receptions for 1,174 yards and 12 touchdowns in 2007.
After the 2007 season, Manningham opted to forgo (forget, not do) his eligibility for his senior year in 2008 and entered the NFL Draft. He finished his career at Michigan with 137 receptions for 2,310 yards and 27 touchdowns. Those marks (in order) placed him ninth, fifth, and fourth in school history.
Manningham was selected in the third round (95th overall) of the 2008 NFL Draft by the New York Giants.
During rookie training camp, Manningham said that he looked forward to playing with fellow former Michigan Wolverine Amani Toomer, who was with New York at the time. Manningham signed a four-year deal worth up to $2.3 million as a rookie.
Manningham has been working on his punt return abilities and competed for the punt returner spot in 2009.
Manningham kicked off the 2009 NFL season by catching three passes for 58 yards and a touchdown en route to the Giants' 23-17 win over the Washington Redskins. He followed this up by catching 10 passes for 150 yards and a juggling sliding catch for a touchdown in the Giants' 33-31 win over the Dallas Cowboys.