They began making electronic products, and for a few years early in the 21st century were the world's biggest maker of mobile phones. Some of its phones, such as the Nokia 1100 and 1110, have sold over 250 million units around the world, and a few others, like the Nokia 3210 and Nokia 3310, sold more than 100 million units.
In 2011, Nokia and Microsoft began a partnership which created Nokia Lumia, a series of smartphones that use the Windows Phone operating system and was meant to replace Symbian as the OS on Nokia's smartphones. Not many of these phones were sold and because of this, Nokia was losing money. Finally, in 2013, Microsoft bought out Nokia's mobile phone business, which became a division of Microsoft called Microsoft Mobile. Microsoft continued to make feature phones with the Nokia brand, but began using the Microsoft brand for its Lumia smartphones. Nokia's other phones, including the Nokia X which used Android, were discontinued, or no longer made.
Nokia also bought the mapping company Navteq in 2011, and changed its name to HERE. Its apps were first available only on Windows Phone as part of the company's deal with Microsoft, but they later became available for Android and iOS. HERE was sold to Volkswagen, BMW, and Daimler in 2015.
Also in 2011, Nokia started a music streaming service called MixRadio. It became part of Microsoft Mobile in 2014, was sold to a Japanese company in 2015, and was eventually shut down in 2016.
In 2013, Nokia bought out the share of its telecommunications division that was held by Siemens of Germany, and this division is now known as Nokia Networks. The French company Alcatel-Lucent was bought by Nokia and merged into Nokia Networks early in 2016, which also included taking over the famous Bell Labs.
Microsoft Mobile sold its feature phone business to HMD Global in 2016, which is licensing the Nokia brand for its own phones. They include the Android-based Nokia 3, Nokia 5, and Nokia 6, and a new version of the popular Nokia 3310 made in 2000.
Research
Research is a way of looking for new information, new understanding, and new facts. A person who does research is called a researcher. Some researchers work in academia. Other researchers work for businesses, for organisations, or for the government. Research is often used for solving problems or increasing available knowledge. This can be done by testing theories and making observations. Research usually prefers to be systematic, organised, and objective. Research is used in many different fields of study such as science, mathematics, and the humanities.
Researchers take part in field or laboratory experiments, reading relevant books, journals or websites, taking notes and making conclusions. Teaching and lecturing is only part of the job of a professor or researcher. When they are not directly teaching classes they are often working on academic research. Learning institutions can vary widely in what they expect from members of their faculty. Most expect faculty members to set up their own laboratories. They hire their own lab employees and obtain their own funding, often from more than one source. Academic researchers often compete for grants to fund research at their own university. The more money researchers can attract, the higher the prestige of that university.
The scientific method is the usual way of doing this kind of research. It is meant to improve understanding of biology, engineering, physics, chemistry and many other fields. With this kind of research, scientists can understand the world, and discover useful things.
Money for research comes from governments, private corporations, and charities. Some of these organizations combine research and development of new products and ways of doing their work.
Any research should be:
Research must be published so the world can learn from it. "Nature", "Science" and "Proceedings of the Royal Society", are general scientific journals. Many special journals are published. Research must pass the peer review process in order to be published.
Electronic Entertainment Expo
The Electronic Entertainment Expo (Exposition) or E3 , first held in 1995, is one of the biggest conferences for video games. Every year in late May or early June, game developers and other professional people gather to show new video games, computer hardware, and features. It is only open to people who have been invited and people visiting must be over eighteen years old. In 2019, personal information of more than 6000 people were leaked. As a result, people were harassed.
Prince Edward Island
Prince Edward Island (PEI; ) is a province of Canada. It is the smallest of Canada's ten provinces. Most of the people on Prince Edward Island speak English. Prince Edward Island was named for the son of King George lll of Britain, and it joined the Dominion of Canada in 1873.
This province is long and 4 to 60 kilometers (2.5 to 37 miles) wide. The capital, and also the largest city, is Charlottetown.
Prince Edward Island is known for being the location for novels written by Lucy Maud Montgomery including "Anne of Green Gables". It is also important for being the "Birthplace of Confederation", because the Charlottetown Conference in 1864 was in Prince Edward Island.
The government of Prince Edward Island is a parliamentary government, with a constitutial monarchy. The monarch (king or queen) right now is Queen Elizabeth II, who is also the monarch for the rest of Canada. The person who represents the Queen is called the Lieutenant Governor.
Antigen
An antigen is a molecule (usually a protein) expressed by a bacterium or virus that is recognized by the adaptive immune system as foreign which can stimulate the production of antibodies and combine specifically with them.
Usually an antigen is a molecule, perhaps on the cell surface of a bacterium or virus.
Antigens are always 'foreign' and trigger an attack. The system is normally tolerant of its own molecules, which don't start an attack. Autoimmune diseases are caused when this safeguard fails.
When an antigen is introduced into the body it causes the production of antibodies. Antigens include bacteria, cells of transplanted organs, plant pollen and toxins.
Antigens "stimulate" the production of antibodies: they do not produce them directly.
Vaccines are examples of antigens in an immunogenic form, which are intentionally administered to a recipient to induce the memory function of the adaptive immune system towards antigens of the pathogen invading that recipient. Vaccines for the seasonal flu virus is a common example.
The first time that a new antigen comes into contact with the body the response of the immune system will be a complete immune response. During this first response, the antigen will cause antibodies to be made.
The next time the same antigen contacts the body, a full-scale immune response is not needed as the body already has a specific antibody available instantly for that antigen.
This means that the body can begin fighting an infection much sooner for illnesses it has encountered before, and takes more time to begin to fight an infection in new illnesses.
Vaccinations usually contain dead bacteria or antigen so the antibodies can familiarise themselves and kill it.
Antigen-presenting cells present antigens in the form of peptides on histocompatibility molecules. The T cells selectively recognize the antigens; depending on the antigen and the type of the histocompatibility molecule, different types of T cells will be activated. For T-cell receptor (TCR) recognition, the peptide must be processed into small fragments inside the cell and presented by a major histocompatibility complex (MHC). The antigen cannot elicit the immune response without the help of an immunologic adjuvant. Similarly, the adjuvant component of vaccines plays an essential role in the activation of the innate immune system.