translate English to German: the PrP that forms prions) has a different structure and is resistant to proteases, the enzymes in the body that can normally break down proteins. The normal form of the protein is called PrPC, while the infectious form is called PrPSc— the 'C' refers to 'cellular' PrP, while the 'Sc' refers to ' scrapie ,' a prion disease occurring in sheep.
1. sporadisch, d. h. zufällig bzw. ohne erkennbare Ursache: PrPC faltet sich „zufällig“ in PrPSc um und löst dadurch die Kettenreaktion aus.