translate English to French: When 1% or more of a bacterial population is resistant to a given drug, clinical success with a regimen that is dependent upon that drug is less likely.16,18,19 The sites of resistance within the mutants are chromosomally located and are not linked.
Ainsi, le médicament B tuera les bacilles qui sont résistants au médicament A et vice versa. En principe, cela signiﬁe qu’un régime associant deux médicaments devrait permettre de traiter un cas courant de tuberculose sensible aux médicaments.