translate English to French: The significant information from this study is that in newborn and paediatric patients with oxygen index of 15-40, continuous exposure to NO between 10 and 30 ppm for 10 minutes showed improvements in oxygenation.
L’oxyde nitrique relâche les muscles lisses vasculaires en liant la portion hémique de la guanylate cyclase cytosolique, activant la guanylate cyclase et augmentant les concentrations intracellulaires du guanosine 3’,5’-monophosphate cyclique, ce qui provoque une vasodilatation.