translate English to French: A trial involving 189 patients with severe chronic obstructive pulmonary disease<21> and the Veterans Administration Cooperative Study, involving 2,295 patients at high-risk,<22> also failed to detect differences in the rates of illness and death among vaccine recipients and control subjects.
De plus, Bolan et ses collaborateurs<19> ont ´e e ` observ´ que le taux d’infection par des s´ rotypes de pneumocoques e e contenus dans le vaccin etait plus elev´ chez les sujets non vaccin´ s ´ ´ e e (67 %) que chez les vaccin´ s (49 %).