jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Ada Tushe | Edmund R. Marinelli | Sara Zumerle | Valentina Andretto | Hanäé Guérin | Annavera Ventura | Olga Slukinova | Giulia Zampardi | Francesco Volpin | Camilla Bonaudo | Alessandro Della Puppa | Giovanna Lollo | Susanna Mandruzzato
Source: International Journal of Nanomedicine (article, 2025-10-01)
Field: Materials Science — Biomaterials

ZnPPIX-Loaded Nanoemulsions Reprogram Immunosuppressive Macrophages in Vitro: A Potential Strategy for Glioblastoma Microenvironment Modulation Our findings suggest that NE-ZnPPIX may represent a novel and effective strategy for remodeling the immunosuppressive TME of GBM in combination with established immune-stimulating therapies. This approach has the potential to enhance the efficacy of immunotherapy by overcoming the tumor immune evasion mechanisms. Tumor microenvironment ; Immune system ; Immunotherapy ; Glioblastoma ; Evasion (ethics) ; Immune modulation ; Modulation (music) Nanoparticle-Based Drug Delivery ; Nanoplatforms for cancer theranostics ; RNA Interference and Gene Delivery
Authors: Shuaijie Jiang | Zechen Zhou | Xiuli Wang | Wei Xu | Wenzhuo Guo | Qingjiang Xiang
Source: Fluid dynamics & materials processing (article, 2025-01-01)
Field: Materials Science — Materials Chemistry

Molecular Dynamics Simulation of Bubble Arrangement and Cavitation Number Influence on Collapse Characteristics In nature, cavitation bubbles typically appear in clusters, engaging in interactions that create a variety of dynamic motion patterns. To better understand the behavior of multiple bubble collapses and the mechanisms of inter... | Find, read and cite all the research you need on Tech Science Press Cavitation ; Bubble ; Mechanics ; Dynamics (music) ; Molecular dynamics ; Materials science ; Physics ; Acoustics Ultrasound and Cavitation Phenomena ; Combustion and Detonation Processes ; Rocket and propulsion systems research
Authors: Aktham Mestareehi
Source: Frontiers in Chemistry (article, 2025-12-01)
Field: Chemistry — Analytical Chemistry

A novel reversed phase high performance liquid chromatography approach for stability-indicating simultaneous analysis of brimonidine tartrate and timolol maleate The validated RP-HPLC method proved accurate, precise, sensitive, and stability-indicating for the simultaneous determination of Brimonidine Tartrate and Timolol Maleate. Its moderate GAC performance supports a balance between analytical rigor and sustainability. These findings establish the method as suitable for routine quality control and stability testing of ophthalmic formulations containing both drugs. Timolol ; High-performance liquid chromatography ; Brimonidine ; Phase (matter) ; Dorzolamide ; Refractometry Analytical Methods in Pharmaceuticals ; Analytical Chemistry and Chromatography ; Pharmaceutical Quality and Counterfeiting
Authors: Ramil Bontilao Arante | John Estillore
Source: Multidisciplinary Science Journal (article, 2025-09-19)
Field: Materials Science — Materials Chemistry

Thermoelectric generator grill heat harvester: A peltier-based solution for alternative power This study investigates the development and evaluation of a Peltier-based thermoelectric generator (TEG) system designed to harness the heat from an improvised griller for off-grid power applications. The system utilises a Peltier tile module to absorb and convert grill thermal energy into electrical energy through a thermal electric generation process. The design incorporates a TEG composed of a Peltier tile module and ceramic plates on both sides that work between a hot source and a cold sink. This optimises heat capture and thermal conversion to maintain the TEG’s efficiency under varying thermal conditions. Experimental tests were conducted under diverse configurations to assess the system's efficiency, reliability, and scalability. Results reveal that the module achieves peak power output (3.6076 W) at a 0.5-inch distance between the Peltier tile and the aluminium circular grill gates, where efficient heat conduction occurs despite a modest temperature difference (ΔT = 14°C). In contrast, increasing the distance to 1.0 and 1.5 inches drastically reduces power output (~0.5 W), even with higher ΔT values (42°C and 32°C), indicating that thermal resistance and poor heat coupling outweigh the benefits of a larger temperature gradient. The time-dependent analysis further confirms that closer heat sources enable faster energy conversion (2 minutes vs. 4-5 minutes). The findings underscore that proximity and thermal management are more critical than temperature differential alone in optimising Peltier-based TEG performance. While viable for low-power applications, the TEG’s efficiency is constrained by material limitations. Alternative designs (e.g., cascaded TEGs) or hybrid systems combining Peltier modules with other energy converters are recommended for higher energy harvesting. Upgrading thermal interface materials, heat sink design, and utilising an active cooling system ensures that the Peltier-based grill heat harvester reaches its potential to generate consistent power output, making it a promising alternative energy solution. Thermoelectric generator ; Thermal energy ; Thermoelectric effect ; Thermal ; Power (physics) ; Thermal resistance ; Work (physics) ; Electricity generation ; Tile Advanced Thermoelectric Materials and Devices ; Innovative Energy Harvesting Technologies ; Geothermal Energy Systems and Applications
Authors: Cínthia Caetano Bonatto | Graziella Anselmo Joanitti | Luciano Paulino Silva
Source: Pharmaceuticals (article, 2025-04-14)
Field: Materials Science — Biomaterials

Red Blood Cell-Based Delivery Systems for the Release of Hemoglobin-Derived Peptides with In Vitro Antitumor Activities <b>Background/Objectives:</b> This study aimed to develop liposomes derived from lipids obtained from red blood cell membranes for potential use in antitumor applications. Hemoglobin hydrolysates exhibiting peptides with known antitumor activities were encapsulated within these liposomes. <b>Methods:</b> The developed liposomal systems were characterized by their physicochemical properties, including size, surface charge, and encapsulation efficiency, and tested in vitro against 4T1 breast cancer cells and NIH3T3 fibroblasts. <b>Results:</b> Results indicated that the liposomes achieved effective encapsulation (88.9%), with nanometer-scale sizes (ranging from 140.7 nm for Blank-Liposomes to 658.3 nm for Pep-Liposomes) and stable colloidal properties. <b>Conclusions</b>: Although cytotoxicity was limited, the use of liposomes from endogenous components, such as red blood cells, demonstrates promise as a complementary approach in anticancer therapy. Liposome ; In vitro ; Hemoglobin ; Cytotoxicity ; Chemistry ; Red blood cell ; Pharmacology ; Membrane ; Hemolysis ; Hydrolysate ; Delivery system ; Biophysics ; Biochemistry ; Medicine ; Immunology ; Biology Nanoparticle-Based Drug Delivery ; Erythrocyte Function and Pathophysiology ; RNA Interference and Gene Delivery
Authors: Shuko Konno | Koji Asanuma | Yoshimune Nonomura
Source: Scientific Reports (article, 2025-07-05)
Field: Materials Science — Polymers and Plastics

Tactile sensation and attractiveness of hair bundles in the combing process The tactile sensation of hair depends on its shape and mechanical properties. However, scientific analysis of hair bundles during the combing process is not a lot. This study explored hand movements and mechanical stimuli using an in-situ tactile sensing system to uncover the physical origin of tactile sensation and the attractiveness of three hair bundle types: straight, curly, and wavy. The straight hair type received the highest attractiveness score (6.9 ± 2.5), closely associated with the sensations of smoothness and slipperiness. While a higher smoothness score correlated with a smaller vertical force F<sub>z</sub>, with a value exceeding eight at F<sub>z</sub> < 1.2 N, a higher slippery sensation score correlated with a smaller moment M<sub>x</sub>, with a value surpassing eight at M<sub>x</sub> < 0.15 N m. Smooth and slippery sensations were implicated as the dominant factors of hair attractiveness. The smooth sensation arises when fingers glide through the hair during hand-combing without encountering resistance, while the slippery sensation is perceived as fingers pass through the ends of the hair with minimal force. Combing ; Attractiveness ; Sensation ; Process (computing) ; Anatomy ; Computer science ; Biology ; Materials science ; Neuroscience ; Art ; Aesthetics ; Composite material Textile materials and evaluations ; Additive Manufacturing and 3D Printing Technologies ; Interactive and Immersive Displays
Authors: Artur Onyshchenko | Vitalii Kovalchuk | Dmytro Husev | Dmitry Anishchenko | Maksym Tymoshyn | Oleg Tsekhansky | Andrii Rubliov | I. V. Melnyk
Source: Eastern-European Journal of Enterprise Technologies (article, 2025-02-05)
Field: Materials Science — General Materials Science

Determining the effect of reinforcing asphalt-concrete coating with synthetic nets on its performance indicators The object of this study is an asphalt concrete cover, the upper layer of which is reinforced with the synthetic material GlasGrid. The subject of research is the performance indicators of asphalt concrete coating. Experimental studies on the effect of reinforced asphalt concrete with synthetic nets on the evolution of rutting and bond strength between layers have been conducted. It has been established that reinforcing the asphalt concrete coating with synthetic nets reduces rutting. At 10,000 load cycles and a temperature of 50 °C, the average value of the rut depth in slab samples without a reinforcing joint was 3.8 mm, and at a temperature of 60 °C – 3.7 mm. In the case of reinforcing the upper layer with a GlasGrid®GG100 net, the depth of the rut at an operating temperature of 50 °C was 3.3, and at an operating temperature of 60 °C – 2.6 mm. With a total number of 20,000 load cycles, the average value of the rut depth without reinforcement of the slab sample is 7.5 mm, and with reinforcement – 5.9 mm. It was established that the rutting resistance of slab samples with reinforcing synthetic nets, in comparison with slab samples without reinforcing material, after the first stage of testing was 13.2 % and 29.7 % after the second stage of testing. It has been established that the maximum vertical shear force that occurs during the destruction of asphalt concrete layers without reinforcement is higher than asphalt concrete layers reinforced with a synthetic mesh. The values of the vertical shear forces without reinforcing the samples are 21.63 kN and 18.46 kN when the samples are reinforced with a synthetic mesh. At the same time, the maximum shear stresses between layers of asphalt concrete core samples without reinforcement are 1.169 MPa, and with reinforcement – 0.988 MPa. Reinforcing the upper layer of the asphalt concrete coating with synthetic meshes will lead to an increase in the durability of the asphalt concrete coating along road sections Asphalt ; Coating ; Environmental science ; Materials science ; Asphalt concrete ; Forensic engineering ; Geotechnical engineering ; Composite material ; Engineering Material Properties and Applications ; Material Properties and Failure Mechanisms ; Structural mechanics and materials
Authors: N. Okezue | H. K. Okorafor
Source: Journal of applied science and environmental management (article, 2025-11-17)
Field: Materials Science — Materials Chemistry

Scrap Metal Recovery and Characterization in Aba, Umuahia and Ohafia in Abia State, South Eastern Nigeria: A Review of Opportunities and Best Practices Scrap metal recycling offers significant resource recovery potential due to its rapidly growing volumes while providing financial gains in developing and emerging economies. Hence, the objective of this paper was to carry out a systematic review of the opportunities and best practices of scrap metal recovery and characterization in Aba, Umuahia and Ohafia, South Eastern Nigeria, using appropriate standard methods, including a site-specific/output approach to provide specific details of individual components of scrap metals and the generation trend. The characterization revealed significant mean recoveries of various scrap metals including iron (1026.03± 78.55 tonnes), aluminum (819.36±59.6 tonnes), copper (88.08±7.62 tonnes), brass (143.47± 16.67 tonnes), lead (106.33±8.36 tonnes), nickel (90.61±7.65 tonnes), LCD/LED screen (1.718±1.06 tonnes), printed circuit board (0.926±0.81 tonnes) hard drive (0.56±0.65 tonnes) and other electrical appliances (1.446 ±1.63 tonnes). The highest volume of scrap metal recovered was recorded in February, and the lowest in July, indicating that seasonal cycles influenced the economic performance of its recovery. Despite nonferrous metals accounting for a greater percentage of the recovered scrap metal, wrought iron was the most abundant scrap metal. Scrap characterization and recovery are a sustainable approach to its management and a source of livelihood for the teeming population. Scrap ; Brass ; Resource recovery ; Characterization (materials science) ; Resource (disambiguation) Material Selection and Properties ; Recycling and Waste Management Techniques ; Materials Engineering and Processing
Authors: A. S. Shuravin
Source: Technobius physics. (article, 2025-09-09)
Field: Materials Science — Materials Chemistry

Correlation between surface nanomorphology and charge density waves in 1T-TaS₂ This study investigates the structural and electronic properties of 1T-TaS₂ using scanning tunneling microscopy (STM) and complementary Fourier analysis. The objective was to correlate surface morphology with the emergence of commensurate charge density wave (CDW) order and to quantify the periodicities governing its modulation. High-resolution STM imaging revealed both the atomic lattice and the superimposed CDW, with measured lattice constant of 0.343 ± 0.02 nm and CDW periodicities of 1.1 ± 0.05 nm and 2.0 ± 0.05 nm. Fourier transforms confirmed reciprocal vectors of 2.9 ± 0.1 nm⁻¹ for the lattice and 0.5–0.9 ± 0.1 nm⁻¹ for the CDW, rotated by approximately 30° with respect to the atomic lattice, consistent with a commensurate × reconstruction. Surface roughness characterization showed root-mean-square variations of 3.5 ± 0.2 nm and terrace widths of only 25–40 nm, reflecting the brittle nature of the crystal and highlighting constraints for achieving atomically stable imaging. Bias-dependent measurements demonstrated contrast inversion between filled and empty states, providing direct evidence of the electronic origin of the CDW. These results confirm the robustness of CDW ordering in 1T-TaS₂, address the research objective of linking morphology with electronic superstructures, and highlight both the opportunities and challenges of using this material as a platform for studying correlated electron phenomena in low-dimensional solids. Reciprocal lattice ; Charge density wave ; Fourier transform ; Lattice constant ; Lattice (music) ; Scanning tunneling microscope ; Surface roughness ; Surface finish 2D Materials and Applications ; Machine Learning in Materials Science ; Electronic and Structural Properties of Oxides
Authors: Ge Tian
Source: Textile & Leather Review (article, 2025-12-19)
Field: Materials Science — Biomaterials

Research on the Acoustic Properties and Sustainable Development Path of Plant Tanned Leather in Musical Instrument Manufacturing This study investigates the processing and performance of a traditional biopolymer-based fibrous material—animal hide—for specialized acoustic applications, addressing the demand for sustainable materials in musical instrument manufacturing. The research compares the chemical modification of goatskin’s collagen fiber network via vegetable tanning (VT) and chrome tanning (CT) to evaluate their effects on the material’s performance as an acoustic membrane. We characterized the structural and mechanical properties of the resulting fibrous materials, including apparent density, Young’s modulus, and tensile strength, and correlated these properties with acoustic performance. Using Fast Fourier Transform (FFT) spectral analysis on twelve independent drumheads (N = 12), we quantified the vibrational behavior under both iso-frequency and iso-tension conditions. This dual-phase approach allowed for the isolation of material properties from mechanical tension effects. The results demonstrate that the vegetable tanning process yields a fibrous structure with higher stiffness and density, which exhibits stronger internal damping properties. This modification of the collagen matrix results in a distinct acoustic profile: a strong fundamental frequency, rapid decay of upper partials, and a shorter overall sustain (T60 decay time of 0.78 s versus 1.15 s for CT), producing a focused and articulate tone. Furthermore, a comparative analysis based on established Life Cycle Assessment (LCA) literature confirms that vegetable tanning is a more sustainable finishing technique, avoiding the heavy metal pollutants associated with CT leather. This research provides quantitative data to support vegetable-tanned fibrous materials not merely as an eco-friendly substitute, but as a distinct class of engineered biomaterial, offering a clear path for developing high-performance, sustainable products by controlling the properties of the collagen fiber network. Ultimate tensile strength ; Path (computing) ; Flexibility (engineering) ; Process (computing) ; Tension (geology) ; Fourier transform ; Sustainable development ; Matrix (chemical analysis) ; Musical instrument Collagen: Extraction and Characterization ; Wound Healing and Treatments ; Silk-based biomaterials and applications
Authors: Y Li | Justin B. Nice | Marya Kozinova | Stephanie Y. Adachi | Linda Marbán | Kristi Elliott | Minghao Sun
Source: Preprints.org (preprint, 2025-10-07)
Field: Chemistry — Organic Chemistry

A Novel In Vitro Potency Assay Demonstrating the Anti-Fibrotic Mechanism of Action of CDCs in Deramiocel Duchenne muscular dystrophy (DMD) is characterized by progressive skeletal and cardiac muscle degeneration driven by inflammation and fibrosis, ultimately leading to cardiomyopathy and premature death. Deramiocel, an allogeneic cell therapy composed of cardiosphere-derived cells (CDCs), has demonstrated potent anti-fibrotic and immunomodulatory effects in preclinical models and clinical trials, including HOPE-2 and its open-label extension (HOPE-2 OLE), where Deramiocel treatment significantly attenuated progression of skeletal and cardiac muscle dysfunction. Here, we describe the development of a novel in vitro potency assay to quantify the anti-fibrotic activity of Deramiocel. Conditioned media (CM) from multiple Deramiocel manufacturing lots significantly suppressed expression of collagen type I alpha 1 (COL1A1) and collagen type III alpha 1 (COL3A1) in primary human dermal fibroblasts compared with non-conditioned media controls, establishing a robust, reproducible readout of anti-fibrotic activity. The effect was dose-dependent and abrogated by sequential depletion of exosomes and soluble proteins, implicating both as critical mediators of Deramiocel’s mechanism of action. Importantly, CDCs in deramiocel lots classified as potent by this assay were shown to exert a clinically meaningful benefit in DMD patients in the HOPE-2 and HOPE-2 OLE studies. This assay represents a mechanistically informative, therapeutically relevant, reproducible, scalable, and regulatory-compliant approach for assessing Deramiocel potency, enabling consistent manufacturing and facilitating the continued development of Deramiocel as a disease-modifying therapy for DMD. In vitro ; Skeletal muscle ; Inflammation ; Mechanism of action ; Duchenne muscular dystrophy ; Muscular dystrophy ; Mechanism (biology) ; Potency ; Myocyte Synthesis and biological activity ; Chemical Synthesis and Analysis
Authors: Jiahui Guo | Yuanjin Zhao
Source: Chinese Science Bulletin (Chinese Version) (article, 2025-07-22)
Field: Materials Science — Surfaces, Coatings and Films

Bioinspired solutions for particles capture: wettable microfibers from frog tongue mechanics 纤维凭借其卓越的柔韧性和广泛的适用性，在口罩制造业中占据着举足轻重的地位。该领域的研究聚焦于开发具有卓越功能的微纤维，以提升口罩的过滤性能。受青蛙舌头粘性唾液辅助的高速捕食过程的启发，我们基于微流控技术构建了一种多孔浸润性微纤维，并验证了其在颗粒捕获方面的有效性。通过将液体石蜡（LP）乳液预分散到聚氨酯（PU）溶液中，借助PU的快速相转化反应，我们连续纺出嵌有分散LP液滴的多孔微纤维。为构建具有类蛙舌界面粘附性能的最佳体系，我们系统评估了多孔微纤维在完全覆盖油滴、部分覆盖油滴和无覆盖油滴情况下的浸润性能。通过3D打印技术，优化后的多孔浸润性微纤维被编织成网格结构并作为过滤层实现了对多种颗粒物，包括花粉、蚊香烟雾、机油乳化烟雾及细菌的捕获和吸附。基于这些结果，我们坚信受青蛙舌头启发的多孔浸润性微纤维及其衍生的口罩体系在未来的过滤、捕获等生物医学领域具有实际应用的价值。 Microfiber ; Nanotechnology ; Materials science ; Polymer science ; Composite material Surface Modification and Superhydrophobicity ; Pickering emulsions and particle stabilization
Authors: Guillem Segarra | Marc Sancho-Adamson | M.I. Trillas | Joan Romanyà
Source: Frontiers in Microbiology (article, 2025-11-25)
Field: Chemistry — Organic Chemistry

Impact of mineral fertilization and Trichoderma application on soil microbiota of young olive trees inoculated with Verticillium dahliae Taken together, those results suggest that mineral fertilization has a much more profound impact on the relative abundance of microorganisms than the introduction of biological control agents such as <i>T. asperellum</i> strain T34. Verticillium dahliae ; Inoculation ; Human fertilization ; Trichoderma ; Strain (injury) ; Microorganism ; Biological pest control ; Verticillium Edible Oils Quality and Analysis ; Plant-Microbe Interactions and Immunity ; Plant Growth Enhancement Techniques
Source: Chemistry International (article, 2025-04-01)
Field: Chemistry — Physical and Theoretical Chemistry

USNC/IUPAC Announces the 2025 Young Observers and IYCN Delegates Abstract The US National Committee for IUPAC of the National Academy of Sciences ( i.e. the US NAO) is pleased to announce the following individuals have been selected as 2025 Young Observers to attend the 53rd IUPAC general Assembly and 50th World Chemistry Congress, to be held in Kuala Lumpur, Malaysia, 12-19 July 2025: Chemical nomenclature ; Chemistry ; Aeronautics ; Engineering ; Organic chemistry History and advancements in chemistry ; Chemistry and Chemical Engineering ; Science, Research, and Medicine