jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Md. Nahid Pervez | Wan Sieng Yeo | Mst. Monira Rahman Mishu | Md. Eman Talukder | Hridoy Roy | Md. Shahinoor Islam | Yaping Zhao | Yingjie Cai | George K. Stylios | Vincenzo Naddeo
Source: Scientific Reports (article, 2023-06-15)
Field: Materials Science — Biomaterials

Electrospun nanofiber membrane diameter prediction using a combined response surface methodology and machine learning approach Despite the widespread interest in electrospinning technology, very few simulation studies have been conducted. Thus, the current research produced a system for providing a sustainable and effective electrospinning process by combining the design of experiments with machine learning prediction models. Specifically, in order to estimate the diameter of the electrospun nanofiber membrane, we developed a locally weighted kernel partial least squares regression (LW-KPLSR) model based on a response surface methodology (RSM). The accuracy of the model's predictions was evaluated based on its root mean square error (RMSE), its mean absolute error (MAE), and its coefficient of determination (R<sup>2</sup>). In addition to principal component regression (PCR), locally weighted partial least squares regression (LW-PLSR), partial least square regression (PLSR), and least square support vector regression model (LSSVR), some of the other types of regression models used to verify and compare the results were fuzzy modelling and least square support vector regression model (LSSVR). According to the results of our research, the LW-KPLSR model performed far better than other competing models when attempting to forecast the membrane's diameter. This is made clear by the much lower RMSE and MAE values of the LW-KPLSR model. In addition, it offered the highest R<sup>2</sup> values that could be achieved, reaching 0.9989. Nanofiber ; Computer science ; Biomedical engineering ; Materials science ; Response surface methodology ; Membrane ; Artificial intelligence ; Machine learning ; Composite material ; Chemistry ; Medicine Electrospun Nanofibers in Biomedical Applications ; Advanced Sensor and Energy Harvesting Materials ; Conducting polymers and applications
Authors: Zeba Tabassum | Anand Mohan | Narsimha Mamidi | Ajit Khosla | Anil Kumar | Pratima R. Solanki | Tabarak Malik | Madhuri Girdhar
Source: IET Nanobiotechnology (review, 2023-03-13)
Field: Materials Science — Biomaterials

Recent trends in nanocomposite packaging films utilising waste generated biopolymers: Industrial symbiosis and its implication in sustainability Uncontrolled waste generation and management difficulties are causing chaos in the ecosystem. Although it is vital to ease environmental pressures, right now there is no such practical strategy available for the treatment or utilisation of waste material. Because the Earth's resources are limited, a long-term, sustainable, and sensible solution is necessary. Currently waste material has drawn a lot of attention as a renewable resource. Utilisation of residual biomass leftovers appears as a green and sustainable approach to lessen the waste burden on Earth while meeting the demand for bio-based goods. Several biopolymers are available from renewable waste sources that have the potential to be used in a variety of industries for a wide range of applications. Natural and synthetic biopolymers have significant advantages over petroleum-based polymers in terms of cost-effectiveness, environmental friendliness, and user-friendliness. Using waste as a raw material through industrial symbiosis should be taken into account as one of the strategies to achieve more economic and environmental value through inter-firm collaboration on the path to a near-zero waste society. This review extensively explores the different biopolymers which can be extracted from several waste material sources and that further have potential applications in food packaging industries to enhance the shelf life of perishables. This review-based study also provides key insights into the different strategies and techniques that have been developed recently to extract biopolymers from different waste byproducts and their feasibility in practical applications for the food packaging business. Sustainability ; Raw material ; Waste management ; Zero waste ; Industrial symbiosis ; Biomass (ecology) ; Resource efficiency ; Food waste ; Environmental science ; Biochemical engineering ; Business ; Environmental economics ; Engineering biodegradable polymer synthesis and properties ; Microplastics and Plastic Pollution ; Nanocomposite Films for Food Packaging
Authors: Minhao Jiang | Xiangyu Yan | Yibo Wang | Fang Pu | Huiling Liu | Yumei Li | Chunfeng Yang | Jiawei Zhu | Xuemeng Liu | Jinsong Ren | Xiaogang Qu
Source: Advanced Functional Materials (article, 2023-03-09)
Field: Chemistry — Inorganic Chemistry

One‐Component Artificial Gustatory System Based on Hydrogen‐Bond Organic Framework for Discrimination of Versatile Analytes Abstract Hydrogen‐bond organic frameworks (HOFs) with excellent structural and luminescent properties have emerged as a promising material for the construction of fluorescence sensors. However, designing a facile, universal and high throughput sensor with multiplex detection capacity still remains challenging. Herein, a one‐component sensor array is constructed that mimics natural gustatory system for accurate and high‐throughput discrimination and identification of versatile analytes. HOF as a single sensing element greatly simplifies the probe preparation in sensor array and detection procedure. Metal ions, proteins and bacteria as the model targets are rapid and accurately discriminated, presenting the universality of the system. Particularly, the system is successfully used for the classification of antibiotic mechanisms. The study expands the application scope of HOFs and provides a facile and universal system for sensing applications. Materials science ; Analyte ; Nanotechnology ; Multiplex ; Sensor array ; Fluorescence ; Scope (computer science) ; Component (thermodynamics) ; Computer science ; Bioinformatics ; Chemistry ; Chromatography ; Machine learning Metal-Organic Frameworks: Synthesis and Applications ; Molecular Sensors and Ion Detection ; Advanced Nanomaterials in Catalysis
Authors: Pramod Ghising | Chandan Biswas | Young Hee Lee
Source: Advanced Materials (review, 2023-01-09)
Field: Materials Science — Materials Chemistry

Graphene Spin Valves for Spin Logic Devices An alternative to charge-based electronics identifies the spin degree of freedom for information communication and processing. The long spin-diffusion length in graphene at room temperature demonstrates its ability for highly scalable spintronics. The development of the graphene spin valve (SV) has inspired spin devices in graphene including spin field-effect transistors and spin majority logic gates. A comprehensive picture of spin transport in graphene SVs is required for further development of spin logic. This review examines the advances in graphene SVs and their role in the development of spin logic devices. Different transport and scattering mechanisms in charge and spin are discussed. Furthermore, the on/off switching energy between graphene SVs and charge-based FETs is compared to highlight their prospects for low-power devices. The challenges and perspectives that need to be addressed for the future development of spin logic devices are then outlined. Spintronics ; Graphene ; Materials science ; Spin (aerodynamics) ; Spin transistor ; Spin valve ; Nanotechnology ; Spin diffusion ; Spin pumping ; Spin engineering ; Logic gate ; Charge (physics) ; Spin Hall effect ; Spin polarization ; Condensed matter physics ; Electrical engineering ; Physics ; Magnetic field ; Quantum mechanics ; Magnetoresistance ; Engineering Graphene research and applications ; Quantum and electron transport phenomena ; Advanced Memory and Neural Computing
Authors: H. Pérez | Omar Jasiel Quintero García | Myriam A. Amezcua‐Allieri | Refugio Rodríguez‐Vázquez
Source: Water Science & Technology (review, 2023-06-07)
Field: Chemistry — Organic Chemistry

Nanotechnology as an efficient and effective alternative for wastewater treatment: an overview The increase in the surface and groundwater contamination due to global population growth, industrialization, proliferation of pathogens, emerging pollutants, heavy metals, and scarcity of drinking water represents a critical problem. Because of this problem, particular emphasis will be placed on wastewater recycling. Conventional wastewater treatment methods may be limited due to high investment costs or, in some cases, poor treatment efficiency. To address these issues, it is necessary to continuously evaluate novel technologies that complement and improve these traditional wastewater treatment processes. In this regard, technologies based on nanomaterials are also being studied. These technologies improve wastewater management and constitute one of the main focuses of nanotechnology. The following review describes wastewater's primary biological, organic, and inorganic contaminants. Subsequently, it focuses on the potential of different nanomaterials (metal oxides, carbon-based nanomaterials, cellulose-based nanomaterials), membrane, and nanobioremediation processes for wastewater treatment. The above is evident from the review of various publications. However, nanomaterials' cost, toxicity, and biodegradability need to be addressed before their commercial distribution and scale-up. The development of nanomaterials and nanoproducts must be sustainable and safe throughout the nanoproduct life cycle to meet the requirements of the circular economy. Sewage treatment ; Wastewater ; Environmental science ; Waste management ; Biochemical engineering ; Engineering ; Environmental engineering Nanomaterials for catalytic reactions ; Membrane Separation Technologies ; Graphene and Nanomaterials Applications
Authors: Shoujie Guan | Jiaxuan Li | Yuyang Wang | Yang Yang | Xun Zhu | Dingding Ye | Rong Chen | Qiang Liao
Source: Advanced Materials (article, 2023-06-15)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Multifunctional MOF‐Derived Au, Co‐Doped Porous Carbon Electrode for a Wearable Sweat Energy Harvesting–Storage Hybrid System As an efficient alternative for harnessing the energy from human's biofluid, a wearable energy harvesting-storage hybrid supercapacitor-biofuel cell (SC-BFC) microfluidic system is established with one multifunctional electrode. The electrode integrates metal-organic framework (MOF) derived carbon nanoarrays with embedded Au, Co nanoparticles on a flexible substrate, and is used for the symmetric supercapacitor as well as the enzyme nanocarriers of the biofuel cell. The electrochemical performance of the proposed electrode is evaluated, and the corresponding working mechanism is studied in depth according to the cyclic voltammetry and density functional theory calculation. The multiplexed microfluidic system is designed to pump and store natural sweat to maintain the continuous biofuel supply in the hybrid SC-BFC system. The biofuel cell module harvests electricity from lactate in sweat, and the symmetric supercapacitor module accommodates the bioelectricity for subsequent utilization. A numerical model is developed to validate the normal operation in poor and rich sweat under variable situations for the microfluidic system. One single SC-BFC unit can be self-charged to ≈0.8 V with superior mechanical durability in on-body testing, as well as energy and power values of 7.2 mJ and 80.3 µW, respectively. It illustrates the promising scenery of energy harvesting-storage hybrid microfluidic system. Materials science ; Wearable computer ; Energy storage ; Electrode ; Porosity ; Doping ; Carbon fibers ; Nanotechnology ; Wearable technology ; Chemical engineering ; Optoelectronics ; Composite material ; Computer science ; Embedded system ; Composite number Supercapacitor Materials and Fabrication ; Advanced Sensor and Energy Harvesting Materials ; Conducting polymers and applications
Authors: Zohra Nausheen Nizami | Hanan E. Aburawi | Abdelhabib Semlali | Khalid Muhammad | Rabah Iratni
Source: Antioxidants (review, 2023-05-26)
Field: Chemistry — Organic Chemistry

Oxidative Stress Inducers in Cancer Therapy: Preclinical and Clinical Evidence Reactive oxygen species (ROS) are metabolic byproducts that regulate various cellular processes. However, at high levels, ROS induce oxidative stress, which in turn can trigger cell death. Cancer cells alter the redox homeostasis to facilitate protumorigenic processes; however, this leaves them vulnerable to further increases in ROS levels. This paradox has been exploited as a cancer therapeutic strategy with the use of pro-oxidative drugs. Many chemotherapeutic drugs presently in clinical use, such as cisplatin and doxorubicin, induce ROS as one of their mechanisms of action. Further, various drugs, including phytochemicals and small molecules, that are presently being investigated in preclinical and clinical studies attribute their anticancer activity to ROS induction. Consistently, this review aims to highlight selected pro-oxidative drugs whose anticancer potential has been characterized with specific focus on phytochemicals, mechanisms of ROS induction, and anticancer effects downstream of ROS induction. Oxidative stress ; Reactive oxygen species ; Cancer ; Pharmacology ; Cancer cell ; Doxorubicin ; Chemistry ; Oxidative phosphorylation ; Cancer research ; Biology ; Biochemistry ; Chemotherapy Free Radicals and Antioxidants ; Bioactive Compounds and Antitumor Agents ; Genomics, phytochemicals, and oxidative stress
Authors: Chrys Wesdemiotis | Kayla Williams‐Pavlantos | Addie R. Keating | Andrew S. McGee | Calum Bochenek
Source: Mass Spectrometry Reviews (review, 2023-04-18)
Field: Chemistry — Spectroscopy

Mass spectrometry of polymers: A tutorial review Ever since the inception of synthetic polymeric materials in the late 19th century, the number of studies on polymers as well as the complexity of their structures have only increased. The development and commercialization of new polymers with properties fine-tuned for specific technological, environmental, consumer, or biomedical applications requires powerful analytical techniques that permit the in-depth characterization of these materials. One such method with the ability to provide chemical composition and structure information with high sensitivity, selectivity, specificity, and speed is mass spectrometry (MS). This tutorial review presents and exemplifies the various MS techniques available for the elucidation of specific structural features in a synthetic polymer, including compositional complexity, primary structure, architecture, topology, and surface properties. Key to every MS analysis is sample conversion to gas-phase ions. This review describes the fundamentals of the most suitable ionization methods for synthetic materials and provides relevant sample preparation protocols. Most importantly, structural characterizations via one-step as well as hyphenated or multidimensional approaches are introduced and demonstrated with specific applications, including surface sensitive and imaging techniques. The aim of this tutorial review is to illustrate the capabilities of MS for the characterization of large, complex polymers and emphasize its potential as a powerful compositional and structural elucidation tool in polymer chemistry. Characterization (materials science) ; Chemistry ; Polymer ; Mass spectrometry ; Nanotechnology ; Commercialization ; Sample preparation ; Biochemical engineering ; Organic chemistry ; Chromatography ; Materials science Mass Spectrometry Techniques and Applications ; Ion-surface interactions and analysis ; Analytical chemistry methods development
Authors: Wei Wang | Huajun Yang | Yichong Chen | Xianhui Bu | Pingyun Feng
Source: Journal of the American Chemical Society (article, 2023-08-04)
Field: Chemistry — Inorganic Chemistry

Cyclobutanedicarboxylate Metal–Organic Frameworks as a Platform for Dramatic Amplification of Pore Partition Effect Ultrafine tuning of MOF structures at subangstrom or picometer levels can help improve separation selectivity for gases with subtle differences. However, for MOFs with a large enough pore size, the effect from ultrafine tuning on sorption can be muted. Here we show an integrative strategy that couples extreme pore compression with ultrafine pore tuning. This strategy is made possible by unique combination of two features of the partitioned <i>acs</i> (<i>pacs</i>) platform: multimodular framework and exceptional tolerance toward isoreticular replacement. Specifically, we use one module (ligand 1, L1) to shrink the pore size to an extreme minimum on <i>pacs</i>. A compression ratio of about 30% was achieved (based on the unit cell <i>c</i>/<i>a</i> ratio) from prototypical 1,4-benzenedicarboxylate-<i>pacs</i> to <i>trans</i>-1,3-cyclobutanedicarboxylate-<i>pacs</i>. This is followed by using another module (ligand 2, L2) for ultrafine pore tuning (<3% compression). This L1-L2 strategy increases the C<sub>2</sub>H<sub>2</sub>/CO<sub>2</sub> selectivity from 2.6 to 20.8 and gives rise to an excellent experimental breakthrough performance. As the shortest cyclic dicarboxylate that mimics <i>p</i>-benzene-based moieties using a bioisosteric (BIS) strategy on <i>pacs</i>, <i>trans</i>-1,3-cyclobutanedicarboxylate offers new opportunities in MOF chemistry. Chemistry ; Selectivity ; Sorption ; Ligand (biochemistry) ; Metal-organic framework ; Chemical engineering ; Partition (number theory) ; Metal ; Nanotechnology ; Organic chemistry ; Receptor ; Catalysis ; Materials science Metal-Organic Frameworks: Synthesis and Applications ; Covalent Organic Framework Applications ; Machine Learning in Materials Science
Authors: Viviana Maffeis | Lukas Heuberger | Anamarija Nikoletić | Cora‐Ann Schoenenberger | Cornelia G. Palivan
Source: Advanced Science (review, 2023-11-20)
Field: Chemistry — Organic Chemistry

Synthetic Cells Revisited: Artificial Cell Construction Using Polymeric Building Blocks The exponential growth of research on artificial cells and organelles underscores their potential as tools to advance the understanding of fundamental biological processes. The bottom-up construction from a variety of building blocks at the micro- and nanoscale, in combination with biomolecules is key to developing artificial cells. In this review, artificial cells are focused upon based on compartments where polymers are the main constituent of the assembly. Polymers are of particular interest due to their incredible chemical variety and the advantage of tuning the properties and functionality of their assemblies. First, the architectures of micro- and nanoscale polymer assemblies are introduced and then their usage as building blocks is elaborated upon. Different membrane-bound and membrane-less compartments and supramolecular structures and how they combine into advanced synthetic cells are presented. Then, the functional aspects are explored, addressing how artificial organelles in giant compartments mimic cellular processes. Finally, how artificial cells communicate with their surrounding and each other such as to adapt to an ever-changing environment and achieve collective behavior as a steppingstone toward artificial tissues, is taken a look at. Engineering artificial cells with highly controllable and programmable features open new avenues for the development of sophisticated multifunctional systems. Artificial cell ; Nanotechnology ; Synthetic biology ; Protocell ; Computer science ; Biomimetics ; Artificial intelligence ; Materials science ; Chemistry ; Membrane ; Biology ; Bioinformatics Advanced Polymer Synthesis and Characterization ; Supramolecular Self-Assembly in Materials ; Polymer Surface Interaction Studies
Authors: Zhiyu Liu | Jiaqi Guo | Yuchen Qiao | Bing Xu
Source: Accounts of Chemical Research (article, 2023-10-26)
Field: Materials Science — Biomaterials

Enzyme-Instructed Intracellular Peptide Assemblies Higher-order or supramolecular protein assemblies, usually regulated by enzymatic reactions, are ubiquitous and essential for cellular functions. This evolutionary fact has provided a rigorous scientific foundation, as well as an inspiring blueprint, for exploring supramolecular assemblies of man-made molecules that are responsive to biological cues as a novel class of therapeutics for biomedicine. Among the emerging man-made supramolecular structures, peptide assemblies, formed by enzyme reactions or other stimuli, have received most of the research attention and advanced most rapidly.In this Account, we will review works that apply enzyme-instructed self-assembly (EISA) to generate intracellular peptide assemblies for developing a new kind of biomedicine, especially in the field of novel cancer nanomedicines and modulating cell morphogenesis. As a versatile and cell-compatible approach, EISA can generate nondiffusive peptide assemblies locally; thus, it provides a unique approach to target subcellular organelles with exceptional cell selectivity. We have arranged this Account in the following way: after introducing the concept, simplicity, and uniqueness of EISA, we discuss the EISA-formed intracellular peptide assemblies, including artificial filaments, in the cell cytosol. Then, we describe the representative examples targeting subcellular organelles, such as mitochondria, endoplasmic reticulum, Golgi apparatus, lysosomes, and the nucleus, by enzyme-instructed intracellular peptide assemblies for potential cancer therapeutics. After that, we highlight the recent exploration of the transcytosis of peptide assemblies for controlling cell morphogenesis. Finally, we provide a brief outlook of enzyme-instructed intracellular peptide assemblies. This Account aims to illustrate the promise of EISA-generated intracellular peptide assemblies in understanding diseases, controlling cell behaviors, and developing new therapeutics from a class of less explored molecular entities, which are substrates of enzymes and become building blocks of self-assembly after the enzymatic reactions. Intracellular ; Golgi apparatus ; Endoplasmic reticulum ; Peptide ; Cell biology ; Biology ; Chemistry ; Nanotechnology ; Biochemistry ; Materials science Supramolecular Self-Assembly in Materials ; RNA Interference and Gene Delivery ; Advanced biosensing and bioanalysis techniques