jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Amine Benazza | Flavien Beffara | Jean‐Louis Auguste | Malini Olivo | U. S. Dinish | Georges Humbert
Source: Optics Express (article, 2023-12-18)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Reliable and easy-to-use SERS spectroscopy probe using a tapered opto-fluidic photonic crystal fiber Surface enhanced Raman spectroscopy (SERS) is one of the most sensitive biosensing techniques that offers label free detection for a variety of applications. Generally, SERS spectroscopy is performed on nano-functionalized planar substrates with plasmonic structures or colloidal nanoparticles. Recently, photonic crystal fibers (PCFs) have gained great interest for SERS based bio sensing applications due to the immense advantages such as improved sensitivity, flexibility and remote sensing capability that it offers compared to the planar substrates. However, the use of PCF based biosensors demand the alignment of it under a microscope, which can affect the reliability of SERS measurements and could be restrictive for practical end use applications. Herein, we aim to develop a tapered suspended core PCF fiber (Tapered-SuC-PCF) that represents an improvement in coupling efficiency and measurement reliability as well as it opens the way to the development of an easy-to-use bio-sensing probes with a plug and play option with conventional Raman spectrometers. We have fabricated several samples of the optimized tapered-SuC-PCF and demonstrated its superior SERS performance compared to standard SuC-PCF fibers with 2 µm core diameter. An excellent SERS measurement reliability is demonstrated using such a fiber in a plug and play type system demonstrating its versatility for practical end use applications. Materials science ; Photonic-crystal fiber ; Raman spectroscopy ; Surface-enhanced Raman spectroscopy ; Optical fiber ; Biosensor ; Nanotechnology ; Optoelectronics ; Optics ; Raman scattering Gold and Silver Nanoparticles Synthesis and Applications ; Plasmonic and Surface Plasmon Research ; Optical Coherence Tomography Applications
Authors: Jing Li | Xueqing Ma | Yifu Wang | Yu Cheng | Yuemin Qin | Jingying Zhai | Xiaojiang Xie
Source: Analytical Chemistry (article, 2023-07-26)
Field: Materials Science — Materials Chemistry

Proton-Coupled Photochromic Hemithioindigo: Toward Photoactivated Chemical Sensing and Imaging We report photoswitchable fluorescent hemithioindigos (HTIs) where the metastable E isomers were stabilized by the proton-bridged intramolecular hydrogen bond. Titration experiments and computational analysis indicated that the E isomers were much more basic than the Z isomers, which enabled photoactivated colorimetric and fluorescent pH response in solvents and polypropylene films. The HTIs exhibited reversibly switchable fluorescence with the Z isomers being the most fluorescent. Moreover, the HTIs were lysosomotropic and the kinetic fluorescence evolution during photoswitching was able to differentiate subcellular compartments with different pH. The combination of photoenhanced basicity, switchable fluorescence, and proton-coupled photochromism lay the groundwork for a broad range of chemical and biological applications. Chemistry ; Fluorescence ; Photochromism ; Intramolecular force ; Photochemistry ; Titration ; Proton ; Hydrogen bond ; Proton NMR ; Molecule ; Inorganic chemistry ; Stereochemistry ; Organic chemistry Photochromic and Fluorescence Chemistry ; Photoreceptor and optogenetics research ; Porphyrin and Phthalocyanine Chemistry
Authors: Jorn de Jong | Maxime A. Siegler | Sander J. Wezenberg
Source: Angewandte Chemie International Edition (article, 2023-12-08)
Field: Chemistry — Organic Chemistry

A Photoswitchable Macrocycle Controls Anion‐Templated Pseudorotaxane Formation and Axle Relocalization Important biological processes, such as signaling and transport, are regulated by dynamic binding events. The development of artificial supramolecular systems in which binding between different components is controlled could help emulate such processes. Herein, we describe stiff-stilbene-containing macrocycles that can be switched between (Z)- and (E)-isomers by light, as demonstrated by UV/Vis and <sup>1</sup> H NMR spectroscopy. The (Z)-isomers can be effectively threaded by pyridinium halide axles to give pseudorotaxane complexes, as confirmed by <sup>1</sup> H NMR titration studies and single-crystal X-ray crystallography. The overall stability of these complexes can be tuned by varying the templating counteranion. However, upon light-induced isomerization to the (E)-isomer, the threading capability is drastically reduced. The axle component, in addition, can form a heterodimeric complex with a secondary isophthalamide host. Therefore, when all components are combined, light irradiation triggers axle exchange between the macrocycle and this secondary host, which has been monitored by <sup>1</sup> H NMR spectroscopy and simulated computationally. Supramolecular chemistry ; Chemistry ; Isomerization ; Pyridinium ; Nuclear magnetic resonance spectroscopy ; Spectroscopy ; Crystallography ; Stereochemistry ; Photochemistry ; Crystal structure ; Organic chemistry Supramolecular Chemistry and Complexes ; Molecular Sensors and Ion Detection ; Porphyrin and Phthalocyanine Chemistry
Authors: Ewoud Vaneeckhaute | Jean‐Max Tyburn | James Kempf | Johan A. Martens | Eric Breynaert
Source: Advanced Science (article, 2023-05-21)
Field: Chemistry — Spectroscopy

Reversible Parahydrogen Induced Hyperpolarization of <sup>15</sup>N in Unmodified Amino Acids Unraveled at High Magnetic Field Amino acids (AAs) and ammonia are metabolic markers essential for nitrogen metabolism and cell regulation in both plants and humans. NMR provides interesting opportunities to investigate these metabolic pathways, yet lacks sensitivity, especially in case of <sup>15</sup> N. In this study, spin order embedded in p-H<sub>2</sub> is used to produce on-demand reversible hyperpolarization in <sup>15</sup> N of pristine alanine and ammonia under ambient protic conditions directly in the NMR spectrometer. This is made possible by designing a mixed-ligand Ir-catalyst, selectively ligating the amino group of AA by exploiting ammonia as a strongly competitive co-ligand and preventing deactivation of Ir by bidentate ligation of AA. The stereoisomerism of the catalyst complexes is determined by hydride fingerprinting using <sup>1</sup> H/D scrambling of the associated N-functional groups on the catalyst (i.e., isotopological fingerprinting), and unravelled by 2D-ZQ-NMR. Monitoring the transfer of spin order from p-H<sub>2</sub> to <sup>15</sup> N nuclei of ligated and free alanine and ammonia targets using SABRE-INEPT with variable exchange delays pinpoints the monodentate elucidated catalyst complexes to be most SABRE active. Also RF-spin locking (SABRE-SLIC) enables transfer of hyperpolarization to <sup>15</sup> N. The presented high-field approach can be a valuable alternative to SABRE-SHEATH techniques since the obtained catalytic insights (stereochemistry and kinetics) will remain valid at ultra-low magnetic fields. Chemistry ; Denticity ; Hyperpolarization (physics) ; Alanine ; Catalysis ; Spin isomers of hydrogen ; Nuclear magnetic resonance spectroscopy ; Amino acid ; Ligand (biochemistry) ; Stereochemistry ; Crystallography ; Crystal structure ; Organic chemistry ; Biochemistry Advanced NMR Techniques and Applications ; Solid-state spectroscopy and crystallography
Authors: Mohammad Asadi Tokmedash | Neha Nagpal | Po‐Yen Chen | J. Scott VanEpps | Jouha Min
Source: Advanced Materials Interfaces (article, 2023-04-21)
Field: Materials Science — Materials Chemistry

Stretchable, Nano‐Crumpled MXene Multilayers Impart Long‐Term Antibacterial Surface Properties Abstract Infections are a significant risk to patients who receive medical implants, and can often lead to implant failure, tissue necrosis, and even amputation. So far, although various surface modification approaches are proposed for prevention and treatment of microbial biofilms on indwelling medical devices, most are too expensive/complicated to fabricate, unscalable, or limited in durability for clinical use. Here, this work presents a new bottom‐up design for fabricating scalable and durable nano‐patterned coatings with dynamic topography for long‐term antibacterial effects. This work shows that MXene layer‐by‐layer (LbL) self‐assembled coatings—with finely tunable crumpled structures with nanometer resolution and excellent mechanical durability—can be successfully fabricated on stretchable poly(dimethylsiloxane) (PDMS). The crumpled MXene coating with sharp‐edged peaks shows potent antibacterial effects against Staphylococcus aureus and Escherichia coli . In addition, this work finds that on‐demand dynamic deformation of the crumpled coating can remove ≥99% of adhered bacterial cells for both species, resulting in a clean surface with restored functionality. This approach offers improved practicality, scalability, and antibacterial durability over previous methods, and its flexibility may lend itself to many types of biomaterials and implantable devices. Materials science ; Durability ; Nanotechnology ; Coating ; Flexibility (engineering) ; Nano- ; Layer (electronics) ; Nanometre ; Composite material MXene and MAX Phase Materials ; Advanced Sensor and Energy Harvesting Materials ; Graphene and Nanomaterials Applications
Authors: Beatrice Muzzi | Martin Albino | Michele Petrecca | Claudia Innocenti | César de Julián Fernández | Giovanni Bertoni | M. R. Ibarra | Mogens Christensen | Maxim Avdeev | C. Marquina | Claudio Sangregorio
Source: Small Methods (article, 2023-08-30)
Field: Materials Science — Materials Chemistry

Defect‐Engineering by Solvent Mediated Mild Oxidation as a Tool to Induce Exchange Bias in Metal Doped Ferrites The crystal site occupancy of different divalent ions and the induction of lattice defects represent an additional tool for modifying the intrinsic magnetic properties of spinel ferrites nanoparticles. Here, the relevance of the lattice defects is demonstrated in the appearance of exchange-bias and in the improvement of the magnetic properties of doped ferrites of 20 nm, obtained from the mild oxidation of core@shell (wüstite@ferrite) nanoparticles. Three types of nanoparticles (Fe0<sub>.95</sub> O@Fe<sub>3</sub> O<sub>4</sub> , Co<sub>0.3</sub> Fe<sub>0.7</sub> O@Co<sub>0.8</sub> Fe<sub>2.2</sub> O<sub>4</sub> and Ni<sub>0.17</sub> Co<sub>0.21</sub> Fe<sub>0.62</sub> O@Ni<sub>0.4</sub> Co<sub>0.3</sub> Fe<sub>2.3</sub> O<sub>4</sub> ) are oxidized. As a result, the core@shell morphology is removed and transformed in a spinel-like nanoparticle, through a topotactic transformation. This study shows that most of the induced defects in these nanoparticles and their magnetic properties are driven by the inability of the Co<sup>(II)</sup> ions at the octahedral sites to migrate to tetrahedral sites, at the chosen mild oxidation temperature. In addition, the appearance of crystal defects and antiphase boundaries improves the magnetic properties of the starting compounds and leads to the appearance of exchange bias at room temperature. These results highlight the validity of the proposed method to impose novel magnetic characteristics in the technologically relevant class of nanomaterials such as spinel ferrites, expanding their potential exploitation in several application fields. Doping ; Metal ; Solvent ; Exchange bias ; Materials science ; Chemical engineering ; Chemistry ; Metallurgy ; Optoelectronics ; Organic chemistry ; Engineering ; Physics Magnetic Properties and Synthesis of Ferrites ; Iron oxide chemistry and applications ; Bauxite Residue and Utilization
Authors: Achraf Noureddine | Benjamin R Marwedel | Lien Tang | Lorél Y. Medina | Rita E. Serda
Source: Cancers (article, 2023-09-19)
Field: Materials Science — Biomaterials

Specific Tumor Localization of Immunogenic Lipid-Coated Mesoporous Silica Nanoparticles following Intraperitoneal Administration in a Mouse Model of Serous Epithelial Ovarian Cancer Immunogenic lipid-coated mesoporous silica nanoparticles (ILM) present pathogen-associated molecular patterns (PAMPs) on the nanoparticle surface to engage pathogen-associated receptors on immune cells. The mesoporous core is capable of loading additional immunogens, antigens or drugs. In this study, the impact of lipid composition, surface potential and intercalation of lipophilic monophosphoryl lipid A (MPL-A) in the lipid coat on nanoparticle properties and cellular interactions is presented. Loading and retention of the model antigen ovalbumin into the mesoporous silica core were found to be similar for all nanoparticle formulations, with presentation of ova peptide (SIINFEKL) by major histocompatibility complex (MHC) evaluated to facilitate the selection of an anionic nanoparticle composition. ILM were able to induce lysosomal tubulation and streaming of lysosomes towards the cell surface in dendritic cells, leading to an enhanced surface presentation of MHC. Myeloid cells robustly internalized all ILM formulations; however, non-myeloid cells selectively internalized cationic ILM in vitro in the presence of 20% serum. Interestingly, ILM administration to the peritoneal cavity of mice with disseminated ovarian cancer resulted in selective accumulation of ILM in tumor-associated tissues (>80%), regardless of nanoparticle surface charge or the presence of MPL-A. Immunofluorescence analysis of the omental tumor showed that ILMs, regardless of surface charge, were localized within clusters of CD11b<sup>+</sup> myeloid cells 24 h post administration. Selective uptake of ILMs by myeloid cells in vivo indicates that these cells outcompete other cell populations in the ovarian tumor microenvironment, making them a strong target for therapeutic interventions. Serous fluid ; Ovarian cancer ; Mesoporous silica ; Cancer research ; Cancer ; Intraperitoneal injection ; Pathology ; Medicine ; Chemistry ; Internal medicine ; Mesoporous material ; Biochemistry Nanoparticle-Based Drug Delivery ; RNA Interference and Gene Delivery ; Nanoplatforms for cancer theranostics
Authors: Jingjing Wang | Xinming Liu | Jinjin Wang | Fei Li | Heng Jiang | Lijie Liu
Source: Luminescence (review, 2023-12-13)
Field: Materials Science — Materials Chemistry

Recent progress on the construction and application of dithienylethene‐based photochromic AIEgens Photochromic fluorescent materials have rapidly developed as a new class of intelligent materials, offering a unique combination of traditional photochromic and organic fluorescent materials. These materials possess remarkable photoresponsiveness that can be observed by the naked eye and exhibit fluorescence color change. Consequently, they have found widespread applications in various domains, including molecular switches, logic encryption, medical diagnosis and treatment, and biosensors. Among the multitude of photochromic systems, those based on dithienylethenes (DTEs) have garnered significant attention due to their exceptional photochromic efficiency, commendable reversible photoresponse and fatigue resistance, as well as excellent photostability and thermal stability. Nevertheless, these photochromic fluorescent materials continue to grapple with the issue of aggregation-caused quenching (ACQ), a common problem faced by traditional fluorescent materials. Therefore, the integration of DTE systems with aggregation-induced emission (AIE) systems presents a promising solution to tackle this predicament, enabling an improved quantum yield for photochromic fluorescent materials in their aggregated state and broadening their range of applications. This review comprehensively summarizes and evaluates the construction strategies and application prospects of DTE-based photochromic AIE luminogens (AIEgens) in recent years, while also providing an outlook on their future development. Photochromism ; Fluorescence ; Nanotechnology ; Materials science ; Quantum yield ; Computer science ; Optics ; Physics Photochromic and Fluorescence Chemistry ; Luminescence and Fluorescent Materials ; Supramolecular Self-Assembly in Materials
Authors: Haiyu Zheng | Thanh Son Pham | Liang‐Yao Chen | YoungPak Lee
Source: Crystals (article, 2023-12-24)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Metamaterial Perfect Absorbers for Controlling Bandwidth: Single-Peak/Multiple-Peaks/Tailored-Band/Broadband Metamaterial absorbers have garnered significant interest due to their unique electromagnetic properties, which facilitate the efficient absorption of electromagnetic radiation in a specific frequency range or multiple frequency ranges. The metamaterial absorbers are designed based on artificially engineered structures that enable tailored absorption properties. These structures might include multiple resonances or incorporate electrical resistive components to achieve broadband absorption. This review paper provides a comprehensive analysis of the progress made in the field of the bandwidth of metamaterial absorbers, encompassing the underlying design principles, key performance characteristics, diverse applications, and perspectives for further research. The paper draws to a conclusion by outlining the potential future directions for further advancements in this exciting area of research, and highlighting the challenges that need to be addressed for the widespread adoption of metamaterial absorbers. Metamaterial ; Broadband ; Bandwidth (computing) ; Resistive touchscreen ; Metamaterial absorber ; Computer science ; Absorption (acoustics) ; Materials science ; Electronic engineering ; Tunable metamaterials ; Optoelectronics ; Telecommunications ; Physics ; Optics ; Engineering Metamaterials and Metasurfaces Applications ; Advanced Antenna and Metasurface Technologies ; Antenna Design and Analysis
Authors: Tayaallen Ramachandran | Mohammad Rashed Iqbal Faruque | K.S. Almugren
Source: Scientific Reports (article, 2023-12-09)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Symmetric left-handed split ring resonator metamaterial design for terahertz frequency applications This work focused on the novel symmetrical left-handed split ring resonator metamaterial for terahertz frequency applications. A compact substrate material known as Silicon with a dimension of 5 µm was adopted in this research investigation. Moreover, several parameter studies were investigated, such as clockwise rotation, array and layer structure designs, larger-scale metamaterials, novel design structure comparisons and electric field distribution analysis. Meanwhile, two types of square-shaped metamaterial designs were proposed in this work. The proposed designs exhibit double and single resonance frequencies respectively, likely at 3.32 and 9.24 THz with magnitude values of - 16.43 and - 17.33 for the first design, while the second design exhibits a response at 3.03 THz with a magnitude value of - 19.90. Moreover, the verification of these results by adopting High-frequency Structure Simulator software indicates only slight discrepancies which are less than 5%. Furthermore, the initial response of the proposed designs was successfully altered by simply rotating the design clockwise or even increasing the dimension of the design. For instance, the first resonance frequency is shifted to the lower band when the first proposed design was rotated 90°. On the other hand, by increasing the size of the metamaterial, more than nine resonance frequencies were gained in each symmetric design. Furthermore, the symmetric metamaterial with a similar width and length of 10 µm dimension was adopted for both design structures to construct an equivalent circuit model by utilising Advanced Design System software. Finally, both unit cell designs were utilised to explore the absorption performances which exhibit four and five peak points. Overall, the altering behaviour by changing physical properties and compact design with acceptable responses become one of the novelties of this research investigation. In a nutshell, the proposed designs can be utilised in terahertz frequency which gives optimistic or advantageous feedback and is relatively suitable for the adopted frequency range. Metamaterial ; Split-ring resonator ; Terahertz radiation ; Resonator ; Resonance (particle physics) ; Dimension (graph theory) ; Computer science ; Physics ; Frequency band ; Optics ; Optoelectronics ; Telecommunications ; Mathematics ; Bandwidth (computing) Metamaterials and Metasurfaces Applications ; Antenna Design and Analysis ; Advanced Antenna and Metasurface Technologies
Authors: Anmol Mahendra | Peter P. Murmu | Susant Kumar Acharya | Atif Islam | Holger Fiedler | Prasanth Gupta | Simon Granville | J. Kennedy
Source: Sensors (article, 2023-05-08)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Shaping Perpendicular Magnetic Anisotropy of Co2MnGa Heusler Alloy Using Ion Irradiation for Magnetic Sensor Applications Magnetic sensors are key elements in many industrial, security, military, and biomedical applications. Heusler alloys are promising materials for magnetic sensor applications due to their high spin polarization and tunable magnetic properties. The dynamic field range of magnetic sensors is strongly related to the perpendicular magnetic anisotropy (PMA). By tuning the PMA, it is possible to modify the sensing direction, sensitivity and even the accuracy of the magnetic sensors. Here, we report the tuning of PMA in a Co<sub>2</sub>MnGa Heusler alloy film via argon (Ar) ion irradiation. MgO/Co<sub>2</sub>MnGa/Pd films with an initial PMA were irradiated with 30 keV <sup>40</sup>Ar<sup>+</sup> ions with fluences (ions·cm<sup>-2</sup>) between 1 × 10<sup>13</sup> and 1 × 10<sup>15</sup> Ar·cm<sup>-2</sup>, which corresponds to displacement per atom values between 0.17 and 17, estimated from Monte-Carlo-based simulations. The magneto optical and magnetization results showed that the effective anisotropy energy (<i>K<sub>eff</sub></i>) decreased from ~153 kJ·m<sup>-3</sup> for the un-irradiated film to ~14 kJ·m<sup>-3</sup> for the 1 × 10<sup>14</sup> Ar·cm<sup>-2</sup> irradiated film. The reduced <i>K<sub>eff</sub></i> and PMA are attributed to ion-irradiation-induced interface intermixing that decreased the interfacial anisotropy. These results demonstrate that ion irradiation is a promising technique for shaping the PMA of Co<sub>2</sub>MnGa Heusler alloy for magnetic sensor applications. Alloy ; Magnetic anisotropy ; Materials science ; Irradiation ; Condensed matter physics ; Ion ; Anisotropy ; Perpendicular ; Optoelectronics ; Nuclear magnetic resonance ; Magnetic field ; Physics ; Optics ; Metallurgy ; Magnetization ; Nuclear physics Heusler alloys: electronic and magnetic properties ; Magnetic properties of thin films ; Wireless Power Transfer Systems
Authors: Sung Sun Yim | Jae Woong Choi | Yong Jae Lee | Ki Jun Jeong
Source: Microbial Cell Factories (article, 2023-02-17)
Field: Materials Science — Biomaterials

Rapid combinatorial rewiring of metabolic networks for enhanced poly(3-hydroxybutyrate) production in Corynebacterium glutamicum We successfully constructed a heterologous PHB biosynthetic pathway and rapidly optimized metabolic networks across central metabolism in C. glutamicum for enhanced production of PHB using glucose or fructose as a sole carbon source in minimal media. We expect that this FACS-based metabolic rewiring framework will accelerate strain engineering processes for the production of diverse biochemicals and biopolymers. Corynebacterium glutamicum ; Metabolic engineering ; Computational biology ; Corynebacterium ; Bacteria ; Production (economics) ; Chemistry ; Synthetic biology ; Metabolic pathway ; Biochemistry ; Biology ; Biotechnology ; Biochemical engineering ; Metabolism ; Enzyme ; Genetics ; Engineering biodegradable polymer synthesis and properties ; Microbial Metabolic Engineering and Bioproduction ; Enzyme Catalysis and Immobilization