jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Ankit Sharma | Largee Biswas | Annu | Dishu | Simran Bhati | Aakash Mathur | Disha Mittal
Source: Indian Journal of Biochemistry and Biophysics (article, 2026-01-01)
Field: Materials Science — Materials Chemistry

Therapeutic approaches of silver nanoparticles against pancreatic cancer Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy, and conventional therapeutic approaches have not produced substantial clinical advantages, with invasive surgery being the sole curative option for patients in the early stages of the illness. It is among the most aggressive and lethal carcinomas, with a five-year survival rate of fewer than 11%. Despite advances in traditional therapies including surgery, chemotherapy, and radiation, the likelihood of survival is still poor due to late-stage detection, extensive stromal barriers, and intrinsic chemoresistance. The recent development in nanotechnology has opened new opportunities for targeted therapy, with silver nanoparticles (AgNPs) showing considerable potential due to their unique physicochemical properties, such as high surface reactivity, localized surface plasmon resonance (LSPR), and ability to penetrate tumour microenvironments. This review investigates AgNPs synthesis approaches, with an emphasis on chemical and green approaches. Green synthesis, which uses plant and algae extracts, provides a sustainable, biocompatible, and environmentally friendly alternative with increased therapeutic value. AgNPs' biological efficacy against PDAC is demonstrated via many molecular routes. AgNPs also show potential as drug carriers for targeted delivery, combating multidrug resistance, and improving the efficacy of traditional medicines through synergistic action. AgNPs shows cytotoxic effects on pancreatic cancer via various mechanism including paraptosis, autophagy and apoptosis. This review consolidates our understanding of AgNPs-mediated therapeutic processes and emphasizes their translational promise in addressing the challenges of current pancreatic cancer treatments. Future research should focus on refining AgNPs design for clinical safety, effectiveness, and targeted administration, opening the path for nanomedicine-based pancreatic cancer treatments. Pancreatic cancer ; Cancer ; Autophagy ; Stromal cell ; Silver nanoparticle ; Targeted therapy ; Nanocarriers ; Cancer cell ; Pancreatic ductal adenocarcinoma Nanoparticles: synthesis and applications ; Nanoplatforms for cancer theranostics ; Nanoparticle-Based Drug Delivery
Authors: Amrin Begum | Navya PN | Pooran Kumar | Srinivasa Reddy Telukutla | Ruchika Ojha | Magdalena Plebanski | Suresh K. Bhargava
Source: Cancers (article, 2026-02-15)
Field: Chemistry — Organic Chemistry

Nature-Inspired Gold(I) Complexes as Anticancer Agents: Ligand Design, Structure–Activity Relationships, and Mechanisms Nature-inspired ligands, including natural product scaffolds and bio-inspired motifs, have emerged as an important source for the development of gold(I) complexes with promising preclinical anticancer activity. This review focuses on structurally characterised gold(I) complexes derived from these ligands, emphasising how ligand structure and gold coordination influence the biological activity. This paper covers the synthesis of nature-inspired gold(I) complexes, alkynyl, N-heterocyclic carbene (NHC), heteroatom-donor, and heterobimetallic complexes, which collectively contribute to enhanced cytotoxicity, stability, and mechanistic diversity. By focusing on these nature-inspired gold(I) complexes, this review provides a concise structure-activity perspective and outlines future opportunities for rational design in anticancer research. Natural product ; Ligand (biochemistry) ; Rational design ; Carbene ; Perspective (graphical) ; Anticancer drug N-Heterocyclic Carbenes in Organic and Inorganic Chemistry ; Catalytic Alkyne Reactions ; Metal complexes synthesis and properties
Authors: Zaichen Xiang | Rui Chen | Shuangyue Wang | Jingjun Qin | Wanyi Zhang | Yucheng Li | Lingyong Zeng | Huixia Luo
Source: arXiv (Cornell University) (article, 2026-02-25)
Field: Materials Science — Materials Chemistry

Oxygen permeability and stability in the entropy-stabilized Co-based Perovskite oxygen permeable membranes Oxygen transport membranes (OTMs), enabling catalytic reaction and gas separation, support crucial chemical engineering processes and decarbonization technologies, but their applications are hindered by limited oxygen permeation fluxes and inadequate long-term stability during operation. Here, a series of high-entropy perovskite OTMs based on La0.5Sr0.5CoO3 were designed and synthesized by the simple sol-gel method. The impact of varying doping ratios on the structure, surface morphology, oxygen permeability, and stability of these high-entropy OTMs was thoroughly examined. At 950 °C, the optimal composition, La0.25Sr0.25Gd0.2Nd0.2Pr0.1CoO3, achieved oxygen permeation fluxes of 1.62 mL min-1 cm-2 under air/He gradient and 1.46 mL min-1 cm-2 under air/CO2, respectively. Remarkably, all high-entropy OTMs demonstrated stable operation for over 100 h in a pure CO2 environment without a significant decline in performance. This finding paves a new way to enhance the structural and oxygen permeation stability of OTMs, and further promotes the application of OTMs in oxy-fuel combustion technologies aimed at improving CO2 capture and storage efficiency. Oxygen ; Permeation ; Perovskite (structure) ; Membrane ; Oxygen permeability ; Oxygen transport ; Catalysis ; Combustion Advancements in Solid Oxide Fuel Cells ; Catalysts for Methane Reforming ; Electrocatalysts for Energy Conversion
Authors: Jun Cheng | Songting Chen | Yi Wang | Nuohang Wan | Songlei Wang | Junni Zhao | Wei Ji | Yunfei Xie
Source: Food Science and Human Wellness (article, 2026-04-01)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Lewis Bases-Assisted Enhanced SERS for Ultra-Sensitive Detection of Pesticide Residues The ability to detect pesticide residues at trace levels is crucial for ensuring consumer health and complying with regulatory standards. Herein, we constructed a hydrophobic layer SERS substrate of silver nanoparticles on the glass surface, utilizing Lewis bases to enhance the interaction between the pesticide and the substrate. This facile method enables the ultrasensitive detection of 6-benzylaminopurine (6-BA), with the lowest detection limit decreasing from 0.01 mg/L to 5´10<sup>-5</sup> mg/L. More importantly, the detection limit of 6-BA in bean sprouts reached 5´10<sup>-4</sup> mg/kg, which is 20 times lower than the allowable residue level (0.01 mg/kg) in legumes set by the EU. Furthermore, the SERS signals of several pesticides, including kinetin, carbendazim, and imidacloprid, can also be enhanced by an order of magnitude. We believe that this method expands the applicability of SERS technology for practical pesticide residue detection, offering a simpler and more sensitive means for analyzing various pesticide contaminants. Pesticide residue ; Detection limit ; Pesticide ; Residue (chemistry) ; Human health ; Maximum Residue Limit Gold and Silver Nanoparticles Synthesis and Applications ; Biosensors and Analytical Detection ; Advanced biosensing and bioanalysis techniques
Authors: Daria Stoia | Ana-Maria Craciun | Gabriela Cherecheș | Olga Soritau | Dana Maniu | Simion Aştilean | Marc Lamy de la Chapelle | Monica Focsan
Source: Journal of Biomedical Optics (article, 2026-02-27)
Field: Materials Science — Electronic, Optical and Magnetic Materials

DNA-hybridization on gold nanospheres: a dual-fluorescence investigation of surface loading and strand length effects The results reveal strand-length and density-dependent conformational dynamics of DNA on AuNSs and establish a robust fluorescence-based method for probing nanoscale assembly. The nanosystem can also be tracked intracellularly, as demonstrated by its detectable signal in fluorescence imaging. Nanoscopic scale ; Fluorescence ; DNA ; Surface (topology) ; Dynamics (music) ; SIGNAL (programming language) Gold and Silver Nanoparticles Synthesis and Applications ; DNA and Nucleic Acid Chemistry ; Advanced biosensing and bioanalysis techniques
Authors: Menghao Li | Hui Hui | Yan Wang | Ying‐Wei Yang
Source: Chemical Science (article, 2026-01-01)
Field: Materials Science — Materials Chemistry

Superstructure-induced enhancement of solid-state triphenylacrylonitrile photochromism <i>via</i> a macrocycle-mediated blocking strategy Developing materials with precisely tunable photochromic properties is crucial for innovative applications, and this requires rational design strategies to overcome photoisomerization constraints imposed by molecular stacking. Herein, we introduce a pillararene-based "blocker" strategy to mitigate π-π stacking of photoisomerizable molecules. The pillararene entity facilitates photochromic chromophore torsion by providing free volume and stabilizes photoisomerization products in conjunction with specific volatile organic compounds (VOCs) through supramolecular interactions. With this strategy, we obtain a solid-state photochromic material induced by VOCs, exhibiting reversible white-to-red color changes. This material's enhanced photochromic behavior, especially when exposed to oxygen-containing VOCs, such as CH<sub>3</sub>OH, HCOOH, and ethyl acetate, expands its potential applications in UV printing, anti-counterfeiting, and multi-dimensional information encryption. Leveraging the pillar-shaped structure and molecular recognition abilities of pillararenes, this study offers a straightforward strategy for the design of multi-stimuli-responsive photochromic molecules and functional supramolecular macrocycles. Photochromism ; Photoisomerization ; Stacking ; Supramolecular chemistry ; Chromophore ; Rational design Photochromic and Fluorescence Chemistry ; Luminescence and Fluorescent Materials ; Crystallography and molecular interactions
Authors: Zhen Liu | Kai Li | R. Wang
Source: Journal of Ovonic Research (article, 2026-03-01)
Field: Materials Science — Materials Chemistry

Effects of Dopant Concentration and Temperature on Upconversion Photoluminescence of Textured CaBi4Ti4O15: Yb3+, Ho3+ Ceramics The upconversion photoluminescence properties of CaBi4Ti4O15 ceramics co-doped with Yb3+, Ho3+ ions were investigated, aiming at their potential application in temperature sensing. Xray diffraction confirmed the successful synthesis and pronounced textured characteristics of the ceramics. Under 980 nm laser excitation, the CaBi 3.96-xYb0.04HoxTi4O15 (x = 0.01, 0.02, 0.03, 0.04) textured ceramics exhibited three distinct emission bands at 549 nm, 660 nm and 759 nm, corresponding to the transitions 5F4→5I8, 5F5→5I8 and 5F5→5I6 of Ho3+ ions. Emission intensities increased with Ho3+ concentration, suggesting the absence of concentration quenching. Powerdependent studies confirmed two-photon processes as the origin of three emission bands. Temperature-dependent measurements revealed monotonic thermal quenching, with CaBi3.93Yb0.04Ho0.03Ti4O15 showing the strongest decrease in fluorescence intensity. Luminescence analysis showed near-infrared emission at 759 nm delivered the highest sensitivity, achieving maximum absolute sensitivity of 0.0072 K-1 and relative sensitivity of 1.71% K-1. These results demonstrate that Yb3+, Ho3+ co-doped CaBi4Ti4O15 textured ceramics are promising candidates for luminescence-based temperature sensing applications. Photoluminescence ; Photon upconversion ; Ceramic ; Dopant ; Analytical Chemistry (journal) ; Luminescence ; Fluorescence ; Diffraction Luminescence Properties of Advanced Materials ; Microwave Dielectric Ceramics Synthesis ; Solid State Laser Technologies
Authors: Shu-Bin Mou | Mu-Peng Luo | Feifei Fang | Shi Cao | Dong Xia Wu | Shou-Guo Wang
Source: Chemical Science (article, 2026-01-01)
Field: Chemistry — Organic Chemistry

Enantioselective C(sp <sup>3</sup> )–H bond functionalization enabled by Cp <sup> <i>x</i> </sup> M( <scp>iii</scp> ) catalysis (M = Co, Rh, Ir) Trivalent group 9 transition metals (Co, Rh, and Ir) bearing pentamethylcyclopentadienyl (Cp <sup><i>x</i></sup> ) or structurally tailored Cp <sup><i>x</i></sup> ligands have emerged as a transformative platform for asymmetric C(sp<sup>3</sup>)-H functionalization. Despite significant progress in C(sp<sup>2</sup>)-H activation, achieving site- and stereoselective transformation of C(sp<sup>3</sup>)-H bonds remains a formidable synthetic challenge due to their intrinsic inertness, increased steric congestion and conformational flexibility. This review provides a comprehensive overview of recent advances in asymmetric C(sp<sup>3</sup>)-H functionalization catalyzed by Cp <sup><i>x</i></sup> M(iii) (M = Co, Rh, Ir) complexes. Particular emphasis is placed on the evolution of chiral ligand frameworks, the strategic use of directing groups, and mechanistic insights into enantioselectivity. By integrating recent developments, this review highlights novel reactions and effective catalytic systems, clarifies remaining challenges, and outlines future research directions in this dynamic field. We anticipate that more novel Cp <sup><i>x</i></sup> M(iii)-catalyzed asymmetric C(sp<sup>3</sup>)-H functionalization reactions will be developed and will find broad applicability in the near future. Enantioselective synthesis ; Surface modification ; Steric effects ; Catalysis ; Ligand (biochemistry) ; Stereoselectivity Catalytic C–H Functionalization Methods ; Organometallic Complex Synthesis and Catalysis ; Cyclopropane Reaction Mechanisms
Authors: Elisa Herrera | Antonio Gil | Manuel Algarra
Source: Journal of Colloid and Interface Science (article, 2026-03-05)
Field: Materials Science — Materials Chemistry

Metal or non-metal doped carbon dots as catalysts for the photodegradation of 4-nitrophenol Dual-metal-doped carbon dots (M@CDs) containing NiFe and RuFe were generated through a one-step hydrothermal route and systematically characterized. Their catalytic performance toward the photodegradation of 4-nitrophenol (4-NP) under UV irradiation (λ = 365 nm) was compared with that of undoped and non-metal (N- and S-doped) CDs. Both NiFe@CDs and RuFe@CDs displayed significantly enhanced catalytic efficiency, following pseudo-first-order kinetics, with NiFe@CDs achieving up to 94% degradation. The improvement is attributed to synergistic charge-transfer interactions between metallic dopants of various oxidation states, which promote charge separation and increase the availability of reactive species during the photodegradation. Photodegradation ; Catalysis ; Metal ; Carbon fibers ; Doping ; Photocatalysis Carbon and Quantum Dots Applications ; Advanced Photocatalysis Techniques ; Nanomaterials for catalytic reactions
Authors: Munnangi Vidya Elizabeth | A. Venkata Sekhar | Nalluri Purnachand | Venkatramaiah Nutalapati | Ponugumati Syam Prasad | G. Naga Raju | Valluri Ravi Kumar | Prof. N. Veeraiah
Source: Luminescence (article, 2026-01-01)
Field: Materials Science — Materials Chemistry

UVB Luminescence and Structural Insights of Gd <sup>3+</sup> ‐Activated Na <sub>2</sub> O–Ga <sub>2</sub> O <sub>3</sub> –B <sub>2</sub> O <sub>3</sub> –Y <sub>2</sub> O <sub>3</sub> Glasses for Applications in Phototherapy Devices In this work, the UVB emission of Gd<sup>3+</sup> ions incorporated into the Na<sub>2</sub>O-Ga<sub>2</sub>O<sub>3</sub>-B<sub>2</sub>O<sub>3</sub>-Y<sub>2</sub>O<sub>3</sub> glass matrix was thoroughly investigated by varying the concentration of Gd<sub>2</sub>O<sub>3</sub>. Photoluminescence measurements revealed a strong and well-defined emission peak at 312 nm, related to the <sup>6</sup>P<sub>7/2</sub> → <sup>8</sup>S<sub>7/2</sub> transition of Gd<sup>3+</sup> ions under 273 nm excitation. Notably, the emission intensity increased nearly threefold as the Gd<sub>2</sub>O<sub>3</sub> concentration rose from 0.2 to 0.8 mol%. The results were examined using Judd-Ofelt analysis and supported by decay kinetics, infrared spectra, ESR spectra, and DSC studies. The enhancement of luminescence was mainly attributed to reduced phonon losses associated with Ga<sub>2</sub>O<sub>3</sub>. However, a decline in emission intensity at 1.0 mol% Gd<sub>2</sub>O<sub>3</sub> was observed, which was ascribed to ion clustering and cross-relaxation processes. Overall, this study demonstrates that tailoring the Gd<sub>2</sub>O<sub>3</sub> concentration provides an effective approach to enhance UVB output in alkali-yttria-gallium-borate glasses. The composition containing 0.8 mol% of Gd<sub>2</sub>O<sub>3</sub> is identified as a promising luminescent material for phototherapeutic applications, particularly in the treatment of skin disorders such as psoriasis and vitiligo, and for use in the fabrication of phototherapy devices. Photoluminescence ; Luminescence ; Ion ; Emission intensity ; Analytical Chemistry (journal) ; Infrared ; Intensity (physics) ; Fabrication Luminescence Properties of Advanced Materials ; Glass properties and applications ; Radiation Detection and Scintillator Technologies
Authors: Haolan Wang | Ying Bao | Baoning Wang | Kaibo Shen | Huiyun Jiang | Wenzhang Fang | Wendao Xu
Source: npj 2D Materials and Applications (article, 2026-03-24)
Field: Materials Science — Materials Chemistry

2D materials assisted terahertz modulators and sensors Terahertz (THz) technology, with its unique advantages of high-bandwidth transmission, non-ionizing radiation, and molecular fingerprint recognition, has emerged as a powerful platform for next-generation wireless communications and non-destructive sensing applications. However, the advancement of THz technology remains constrained, partly due to the lack of efficient functional devices. Consequently, the materials used to fabricate the devices have drawn significant attention. Two-dimensional (2D) materials, with their atomic-scale thickness and unique optoelectronic properties, allow subwavelength-scale manipulation of light’s phase, amplitude, and polarization, making them ideal for THz modulator and sensor development. This review comprehensively examines 2D material-based THz modulators and sensors, highlighting key materials (graphene, TMDs, MXenes) and the operational mechanisms that enable their functionality. We analyze state-of-the-art device implementations and address current challenges in the field. These 2D materials demonstrate significant potential for advancing THz technology through innovative device designs. Terahertz radiation ; Key (lock) ; Wireless ; Fingerprint (computing) ; Terahertz metamaterials ; Electronics 2D Materials and Applications ; MXene and MAX Phase Materials ; Terahertz technology and applications
Authors: M. Taheri | zohreh feizabadi
Source: Scientific Reports (article, 2026-02-15)
Field: Materials Science — Materials Chemistry

Effect of thermal and gold nanoparticles on the optoelectronic properties of graphene oxide In this study, the effects of thermal reduction and gold nanoparticles on the optoelectronic properties of thin graphene oxide films was systematically investigated. Thermal annealing partially reduced graphene oxide to reduced graphene oxide, leading to a restoration of the sp2 carbon network and a marked improvement in electrical conductivity. Under 405 nm laser illumination with a power of 50 mW and a bias voltage of 30 V, the reduced graphene oxide photodetector exhibited a high photocurrent of 33.3 µA and a responsivity of 0.67 mA W⁻1, with rise and fall times of approximately 11.12 s and 10.27 s, respectively. Incorporation of Au NPs resulted in the reduced graphene oxide/gold nanocomposite showing a lower photocurrent (12.23 µA) and responsivity (0.25 mA W⁻1); however, it demonstrated improved reversibility and a faster rise time of 9.87 s. The external quantum efficiency was estimated to be ~0.21% for reduced graphene oxide and ~0.08% for reduced graphene oxide/gold. These results indicate that thermal reduction is the dominant factor in enhancing photoresponse, while Au NPs primarily improve response stability and reversibility. The findings highlight the potential of reduced graphene oxide-based structures, with controlled gold nanoparticle incorporation, for developing efficient and stable graphene-based photodetectors. Graphene ; Responsivity ; Oxide ; Photocurrent ; Graphene oxide paper ; Colloidal gold ; Photodetector ; Nanoparticle Graphene research and applications ; Plasmonic and Surface Plasmon Research ; Graphene and Nanomaterials Applications
Authors: Sydney Tindall | Meredith McQuerry | Josephine Bolaji
Source: Polymers (article, 2026-01-12)
Field: Materials Science — Polymers and Plastics

A Review of Textile Hydrogel Integration in Firefighting Personal Protective Clothing Traditional firefighting protective clothing materials, such as meta- and para-aramid fibers, provide significant thermal protection but often fail to adequately manage heat stress and moisture, especially due to the incorporation of semi-permeable membranes within the three-layer garment structure known as turnout gear. Integrating hydrogels into textiles for firefighting personal protective clothing (PPC) could enhance thermoregulation and moisture management, providing firefighters with improved comfort and safety. Hydrogels are three-dimensional, hydrophilic polymer networks capable of holding substantial amounts of water. Their high water content and excellent thermal properties make them ideal for cooling applications. Therefore, this review focuses on the potential of hydrogel-infused textiles to improve firefighters' PPC by enhancing thermal comfort and moisture management. Specifically, hydrogel structures and engineered properties for enhanced performance are presented, including smart hydrogels and hydration customization mechanisms. Hydrogel integration into firefighting PPC for moisture management and improved thermoregulation is explored, including current and future market projections and state-of-the-art clinical trial findings. Overall, the future of hydrogel-integrated textiles for firefighting PPC is bright, with numerous advancements and trends poised to enhance the safety, comfort, and performance of protective gear. Firefighting ; Clothing ; Self-healing hydrogels ; Textile ; Personal protective equipment ; Thermal comfort ; Moisture Textile materials and evaluations ; Thermoregulation and physiological responses ; Hydrogels: synthesis, properties, applications
Authors: V. S. Abhisha | Lakshmipriya Somasekharan | K. S. Sisanth | S. Thomas | Ranimol Stephen
Source: Polymers for Advanced Technologies (article, 2026-02-01)
Field: Materials Science — Electronic, Optical and Magnetic Materials

A Pathway to Better <scp>EMI</scp> Shielding Performance in Natural Rubber Through Ternary Carbonaceous Filler Systems ABSTRACT In the present study, we fabricated and characterized ternary hybrid fillers of conductive carbon black (CCB), carbon nanotubes (CNT), and reduced graphene oxide (RGO) reinforced natural rubber (NR) composites. The ternary filler system exhibited good filler‐polymer interaction as observed from the cure characteristics and mechanical properties. We used impedance analysis to study the dielectric permittivity and associated polarization mechanisms, and the AC conductivity was fitted using the Jonsher Power law. The presence of functional groups on the ternary nanofiller surfaces caused increased filler‐filler interactions, leading to the formation of an excellent conductive network. Mechanical and viscoelastic studies revealed the reinforcing effect of the CCB, CNT, and RGO fillers. The theoretical models, such as Nicolais‐Narkis and Turcsanyi, were employed to predict the tensile strength. Morphological analysis confirms the homogeneous dispersion of filler in the matrix. The present system also demonstrated excellent electromagnetic interference (EMI) shielding performance, with the highest shielding effectiveness (SE) values of 37.4 and 35.3 dB at 12 GHz for the ternary composites, satisfying commercial requirements. Ternary operation ; Natural rubber ; Graphene ; Electromagnetic shielding ; Ultimate tensile strength ; Carbon nanotube ; Carbon black ; Filler (materials) ; Electrical conductor Electromagnetic wave absorption materials ; Natural Fiber Reinforced Composites ; Smart Materials for Construction