jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Tongliang Zhou | Greta Utecht‐Jarzyńska | Michal Szostak
Source: Coordination Chemistry Reviews (article, 2024-04-26)
Field: Chemistry — Organic Chemistry

Ring-expanded N-heterocyclic carbene (reNHC) complexes: Applications in transition metal catalysis Chemistry ; Carbene ; Ring (chemistry) ; Catalysis ; Transition metal ; Organometallic chemistry ; Combinatorial chemistry ; Transition metal carbene complex ; Homogeneous catalysis ; Ligand (biochemistry) ; Organic chemistry N-Heterocyclic Carbenes in Organic and Inorganic Chemistry ; Catalytic Cross-Coupling Reactions ; Synthetic Organic Chemistry Methods
Authors: Lingxiao Chen | Feng Yang
Source: Journal of Separation Science (article, 2024-05-31)
Field: Chemistry — Spectroscopy

Applications of magnetic solid‐phase extraction in the sample preparation of natural product analysis (2020–2023) Sample preparation, including extraction, separation, and purification, is a vital process for natural product analysis. As an attractive sample pretreatment method, magnetic solid-phase extraction (MSPE) has gained plenty of attention, mainly due to its simpler operation, less consumption of organic solvents, and shorter processing time than traditional SPE. This updated review is devoted to summarizing the applications of MSPE based on different magnetic nanomaterials in the analysis of various natural products in complex matrixes, such as biological samples, plants, and Chinese herbal preparations in the past four years (2020-2023). The preparation and fabrication of different materials are briefly introduced. Furthermore, the extraction mechanism and interaction forces between adsorbent and analytes are elaborated, and the advantages and disadvantages of different adsorbents coupled with various analytical methods for MSPE of different natural products are summarized. Moreover, the future trends and opportunities for MSPE in the natural product analysis are discussed. It is expected that this work can provide updated information for future research on the applications of MSPE in such fields. Solid phase extraction ; Sample preparation ; Extraction (chemistry) ; Process engineering ; Analyte ; Computer science ; Adsorption ; Biochemical engineering ; Chromatography ; Chemistry ; Engineering Analytical Chemistry and Chromatography ; Analytical chemistry methods development ; Mesoporous Materials and Catalysis
Authors: Natali Joma | Patrick‐Brian Bielawski | Anjali Saini | Ashok Kakkar | Dušica Maysinger
Source: Aging Cell (article, 2024-04-29)
Field: Materials Science — Materials Chemistry

Nanocarriers for natural polyphenol senotherapeutics Senescence is a heterogenous and dynamic process in which various cell types undergo cell-cycle arrest due to cellular stressors. While senescence has been implicated in aging and many human pathologies, therapeutic interventions remain inadequate due to the absence of a comprehensive set of biomarkers in a context-dependent manner. Polyphenols have been investigated as senotherapeutics in both preclinical and clinical settings. However, their use is hindered by limited stability, toxicity, modest bioavailability, and often inadequate concentration at target sites. To address these limitations, nanocarriers such as polymer nanoparticles and lipid vesicles can be utilized to enhance the efficacy of senolytic polyphenols. Focusing on widely studied senolytic agents-specifically fisetin, quercetin, and resveratrol-we provide concise summaries of their physical and chemical properties, along with an overview of preclinical and clinical findings. We also highlight common signaling pathways and potential toxicities associated with these agents. Addressing challenges linked to nanocarriers, we present examples of senotherapeutic delivery to various cell types, both with and without nanocarriers. Finally, continued research and development of senolytic agents and nanocarriers are encouraged to reduce the undesirable effects of senescence on different cell types and organs. This review underscores the need for establishing reliable sets of senescence biomarkers that could assist in evaluating the effectiveness of current and future senotherapeutic candidates and nanocarriers. Nanocarriers ; Context (archaeology) ; Biology ; Fisetin ; Computational biology ; Pharmacology ; Bioinformatics ; Quercetin ; Drug ; Biochemistry ; Antioxidant Advanced Nanomaterials in Catalysis ; Telomeres, Telomerase, and Senescence ; Polydiacetylene-based materials and applications
Authors: Jiaqi Zhou | Bo Zhu | Wei Zhao | Ye Zhang | Anping Zhu | Chengrui Di | Kun Qiao
Source: Composites Communications (article, 2024-07-23)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Pomegranate-like ZnMn2O4 nanospheres/carbon fiber network for interface enhancement structure-function PEEK composites with good electromagnetic interference shielding and thermal conductivity Composite material ; Materials science ; Peek ; Electromagnetic shielding ; Thermal conductivity ; Electromagnetic interference ; Thermal ; Polymer ; Computer science ; Telecommunications Electromagnetic wave absorption materials ; Conducting polymers and applications ; Transition Metal Oxide Nanomaterials
Authors: Hai Xie | Jinmei Li | Rui Yang | Juan Yang | Tingmei Wang | Qihua Wang
Source: RSC Advances (article, 2024-01-01)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Controllable fabrication of CoNi bimetallic alloy for high-performance electromagnetic wave absorption With the coming era of artificial intelligence (AI) dominated by high-tech electronics, developing high-performance microwave absorption materials (MAMs) is imperative to solve the problem of increasing electromagnetic inference and pollution. Herein, a metal-organic framework (MOF)-derived CoNi bimetallic alloy (CoNi/C) with an irregular rod-like structure is prepared by a thermal reduction method. Introducing the CoNi alloy facilitates the balance between conduction loss and polarization loss and forms good impedance matching, leading to excellent microwave absorption performance. Interestingly, the optimization of absorption performance can be further achieved by controllably modulating the molar ratio of Co and Ni (Co<sup>2+</sup>/Ni<sup>2+</sup>). As expected, the obtained CoNi/C delivers excellent microwave absorption performance with a minimum reflection loss (RL<sub>min</sub>) of -50.80 dB at 10.40 GHz and an effective absorption bandwidth (EAB) of 3.28 GHz (8.91-12.19 GHz) with a filler loading of 50 wt% at 2.0 mm. In addition, the CoNi/C can reach a maximum EAB of 4.77 GHz (12.99-17.76 GHz) at a low thickness of 1.5 mm, spanning nearly the entire Ku band. The CoNi<sub>3</sub>/C also exhibits an impressive RL<sub>min</sub> of -44.84 dB at 3.28 GHz in the S band. This work offers a novel strategy to modulate the magnetic/electric properties of MOF-derived MAMs. Bimetallic strip ; Fabrication ; Alloy ; Absorption (acoustics) ; Materials science ; Optoelectronics ; Composite material ; Metallurgy ; Metal Electromagnetic wave absorption materials ; Advanced Antenna and Metasurface Technologies ; Metamaterials and Metasurfaces Applications
Authors: Sanghyun Ban | Jangseop Lee | Yoori Seo | Wootae Lee | Taehoon Kim | Hyunsang Hwang
Source: Advanced Electronic Materials (article, 2024-12-10)
Field: Materials Science — Materials Chemistry

Advances in Ovonic Threshold Switch Selector Technologies for Storage Class Memory: From Fundamentals to Development and Beyond Abstract The explosive increase in the demand for data driven by advancements in artificial intelligence technology and rapid expansion of data centers necessitates storage class memory (SCM) capable of alleviating data traffic and workload issues. The success of SCM depends heavily on the selector. The ovonic threshold switch (OTS), a chalcogenide‐based amorphous thin film, has garnered increasing attention as a selector owing to its suitable characteristics. Here, OTS devices based on various chalcogens (tellurium, selenium, and sulfur) are reviewed, and how the selection of a chalcogen should be dictated by the specific requirements of the application is highlighted, because the OTS characteristics vary significantly depending on the choice. Additionally, OTS characteristic engineering from multiple perspectives, including material engineering via elemental doping, electrode engineering, physical property engineering via post‐treatment, and structural/interface engineering using multiple layers is reviewed. Finally, selector‐only memory (SOM) is examined, which offers better scalability and performance than the existing one‐memory and one‐selector structure, which combines an OTS with phase‐change memory. Moreover, a cost‐effective 3D vertical X‐point memory is also discussed, emphasizing that its ultimate implementation should be achieved using an SOM. Thus, insights and guidelines for OTS material design, stack engineering, and cell parameter design are provided here. Chalcogenide ; Materials science ; Scalability ; Chalcogen ; Phase-change memory ; Computer science ; Computer data storage ; Stack (abstract data type) ; Nanotechnology ; Computer hardware ; Optoelectronics ; Layer (electronics) Phase-change materials and chalcogenides ; Chalcogenide Semiconductor Thin Films ; Transition Metal Oxide Nanomaterials
Authors: Hongsheng Liang | Shengchong Hui | Limin Zhang | Kai Tao | Qiang Chen | Wei Lü | Hongjing Wu
Source: Small (article, 2024-11-27)
Field: Materials Science — Electronic, Optical and Magnetic Materials

High‐Density Dual Atoms Pairs Coupling for Efficient Electromagnetic Wave Absorbers Dual atoms (DAs), characterized by flexible structural tunability and high atomic utilization, hold significant promise for atom-level coordination engineering. However, the rational design with high-density heterogeneous DAs pairs to promote electromagnetic wave (EMW) absorption performance remains a challenge. In this study, high-density Ni─Cu pairs coupled DAs absorbers are precisely constructed on a nitrogen-rich carbon substrate, achieving an impressive metal loading amount of 4.74 wt.%, enabling a huge enhancement of the effective absorption bandwidth (EAB) of EMW from 0 to 7.8 GHz. Furthermore, the minimum reflection loss (RL<sub>min</sub>) is -70.96 dB at a matching thickness of 3.60 mm, corresponding to an absorption of >99.99% of the incident energy. Both experimental results and theoretical calculations indicate that the synergistic effect of coupled Ni─Cu pairs DAs sites results in the transfer of electron-rich sites from the initial N sites to the Cu sites, which induces a strong asymmetric polarization loss by this redistribution of local charge and significantly improves the EMW absorption performance. This work not only provides a strategy for the preparation of high-density DA pairs but also demonstrates the role of coupled DA pairs in precisely tuning coordination symmetry at the atomic level. Materials science ; Coupling strength ; Absorption (acoustics) ; Atom (system on chip) ; Metal ; Polarization (electrochemistry) ; Molecular physics ; Atomic physics ; Optoelectronics ; Chemistry ; Condensed matter physics ; Physics Electromagnetic wave absorption materials ; MXene and MAX Phase Materials ; Advanced Antenna and Metasurface Technologies
Authors: Wasana N. Marasinghe | K. G. L. R. Jayathunge | Rohan S. Dassanayake | Rumesh Liyanage | Pasan Chinthana Bandara | Suranga M. Rajapaksha | Chamila Gunathilake
Source: Journal of Composites Science (article, 2024-03-21)
Field: Materials Science — Biomaterials

Structure, Properties, and Recent Developments in Polysaccharide- and Aliphatic Polyester-Based Packaging—A Review Food packaging plays an imperative role in the food processing sector by safeguarding foods from their point of harvesting until the moment of consumption. In recent years, biopolymers have attracted the attention of the scientific community as an alternative to conventional packaging materials. Among the available biopolymer sources, a lot of the focus has been on polysaccharides due to their superior barrier properties against gases, oils, and odors and their processing versatility. Moreover, there is also a growing interest in aliphatic polyester as a potential replacement for petrochemical-based synthetic plastics. Both polysaccharides and aliphatic polyesters have gained popularity in sustainable food packaging due to their unique characteristics, including their low cost, availability, biodegradability, gas and moisture barrier properties, film-forming capabilities, excellent heat resistance, and ability to be processed into films, trays, and coatings. This review highlights the structural features, properties, and recent advancements of several vital polysaccharides, namely, starch, chitosan, cellulose, alginate, pectin, carrageenan, and aliphatic polyesters, including polylactic acid (PLA) and polyhydroxybutyrate (PHB) for developing packaging materials, and their applications in the food industry. Conventional packaging and future perspectives of biopolymer-based food packaging are also comprehensively covered in this review. Polyester ; Polymer science ; Polysaccharide ; Materials science ; Biochemical engineering ; Chemistry ; Engineering ; Organic chemistry ; Composite material biodegradable polymer synthesis and properties ; Nanocomposite Films for Food Packaging ; Advanced Cellulose Research Studies
Authors: Shaimaa M. I. Alexeree | Hanan Abou-Seri | Hala E. Shams EL-Din | Doaa Youssef | Marwa A. Ramadan
Source: Lasers in Medical Science (article, 2024-01-22)
Field: Materials Science — Materials Chemistry

Green synthesis of silver and iron oxide nanoparticles mediated photothermal effects on Blastocystis hominis The evolution of parasite resistance to antiparasitic agents has become a serious health issue indicating a critical and pressing need to develop new therapeutics that can conquer drug resistance. Nanoparticles are novel, promising emerging drug carriers that have demonstrated efficiency in treating many parasitic diseases. Lately, attention has been drawn to a broad-spectrum nanoparticle capable of converting absorbed light into heat via the photothermal effect phenomenon. The present study is the first to assess the effect of silver nanoparticles (Ag NPs) and iron oxide nanoparticles (Fe<sub>3</sub>O<sub>4</sub> NPs) as sole agents and with the combined action of the light-emitting diode (LED) on Blastocystis hominins (B. hominis) in vitro. Initially, the aqueous synthesized nanoparticles were characterized by UV-Vis spectroscopy, zeta potential, and transmission electron microscopy (TEM). The anti-blastocyst efficiency of these NPs was tested separately in dark conditions. As these NPs have a wide absorption spectrum in the visible regions, they were also excited by a continuous wave LED of wavelength band (400-700 nm) to test the photothermal effect. The sensitivity of B. hominis cysts was evaluated using scanning laser confocal microscopy whereas the live and dead cells were accurately segmented based on superpixels and the k-mean clustering algorithm. Our findings showed that this excitation led to hyperthermia that induced a significant reduction in the number of cysts treated with photothermally active NPs. The results of this study elucidate the potential role of photothermally active NPs as an effective anti-blastocystis agent. By using this approach, new therapeutic antiparasitic agents can be developed. Photothermal therapy ; Nanoparticle ; Materials science ; Blastocystis ; Confocal microscopy ; Nanotechnology ; Phototoxicity ; Biophysics ; Chemistry ; In vitro ; Microbiology ; Biology ; Biochemistry Quantum Dots Synthesis And Properties ; Advanced Photocatalysis Techniques ; Nanoparticles: synthesis and applications
Authors: Daniel Ungureanu | Brînduşa Tiperciuc | Cristina Nastasă | Ioana Ionuț | Gabriel Marc | Ilioara Oniga | Ovidiu Oniga
Source: Pharmaceutics (article, 2024-01-09)
Field: Chemistry — Organic Chemistry

An Overview of the Structure–Activity Relationship in Novel Antimicrobial Thiazoles Clubbed with Various Heterocycles (2017–2023) Antimicrobial resistance is an increasing problem for global public health. One of the strategies to combat this issue is the synthesis of novel antimicrobials through rational drug design based on extensive structure-activity relationship studies. The thiazole nucleus is a prominent feature in the structure of many authorized antimicrobials, being clubbed with different heterocycles. The purpose of this review is to study the structure-activity relationship in antimicrobial thiazoles clubbed with various heterocycles, as reported in the literature between 2017 and 2023, in order to offer an overview of the last years in terms of antimicrobial research and provide a helpful instrument for future research in the field. Antimicrobial ; Thiazole ; Antimicrobial drug ; Combinatorial chemistry ; Biochemical engineering ; Chemistry ; Engineering ; Organic chemistry Synthesis and biological activity ; Click Chemistry and Applications ; Synthesis and Biological Evaluation
Authors: Kevin J. Hughes | Jianjun Cheng | Kavita A. Iyer | Krittika Ralhan | Magesh Ganesan | Chia‐Wei Hsu | Yutao Zhan | Xinning Wang | Bowen Zhu | Menghua Gao | Huaimin Wang | Yue Zhang | Jiaxing Huang | Qiongqiong Angela Zhou
Source: ACS Nano (article, 2024-06-18)
Field: Materials Science — Biomaterials

Unveiling Trends: Nanoscale Materials Shaping Emerging Biomedical Applications The realm of biomedical materials continues to evolve rapidly, driven by innovative research across interdisciplinary domains. Leveraging big data from the CAS Content Collection, this study employs quantitative analysis through natural language processing (NLP) to identify six emerging areas within nanoscale materials for biomedical applications. These areas encompass self-healing, bioelectronic, programmable, lipid-based, protein-based, and antibacterial materials. Our Nano Focus delves into the multifaceted utilization of nanoscale materials in these domains, spanning from augmenting physical and electronic properties for interfacing with human tissue to facilitating intricate functionalities like programmable drug delivery. Nanotechnology ; Materials science ; Nanoscopic scale Silk-based biomaterials and applications ; RNA Interference and Gene Delivery ; Electrospun Nanofibers in Biomedical Applications
Authors: Kristina Mervič | Martin Šala | Sarah Theiner
Source: TrAC Trends in Analytical Chemistry (article, 2024-02-02)
Field: Chemistry — Spectroscopy

Calibration approaches in laser ablation inductively coupled plasma mass spectrometry for bioimaging applications Laser ablation (LA) in combination with inductively coupled plasma mass spectrometry (ICP-MS) is a technically advanced micro-analytical method for direct sampling of solid materials and allows the determination of a majority of elements from the periodic table. In recent years, the technology has undergone major improvements in hardware, software and the methodology, which have led to a significant reduction of the analysis time, higher spatial resolution/image quality, better sensitivity and signal to noise ratios. Reliable and validated quantification procedures remain one of the bottlenecks in LA-ICPMS bioimaging. This review provides a comprehensive overview on different quantification strategies commonly used for bioimaging applications by LA-ICPMS. The advantages and drawbacks of existing quantification approaches in terms of analytical capabilities will be critically discussed and showcases of their application to biological samples will be presented. Recent developments and future perspectives of the field will be discussed. Calibration ; Inductively coupled plasma mass spectrometry ; Laser ablation ; Mass spectrometry ; Laser ; Plasma ; Materials science ; Analytical Chemistry (journal) ; Chemistry ; Optics ; Environmental chemistry ; Physics ; Chromatography ; Nuclear physics Mass Spectrometry Techniques and Applications ; Analytical chemistry methods development ; Ion-surface interactions and analysis
Authors: Sanja Ćavar Zeljkovıć | Nuria De Diego | Lukáš Drašar | Jaroslav Nisler | Libor Havlı́ček | Lukáš Spíchal | Petr Tarkowski
Source: Journal of Experimental Botany (article, 2024-03-23)
Field: Chemistry — Spectroscopy

Comprehensive LC-MS/MS analysis of nitrogen-related plant metabolites We have developed and validated a novel LC-MS/MS method for simultaneously analyzing amino acids, biogenic amines, and their acetylated and methylated derivatives in plants. This method involves a one-step extraction of 2-5 mg of lyophilized plant material followed by fractionation of different biogenic amine forms, and exploits an efficient combination of hydrophilic interaction liquid chromatography (HILIC), reversed phase (RP) chromatography with pre-column derivatization, and tandem mass spectrometry (MS). This approach enables high-throughput processing of plant samples, significantly reducing the time needed for analysis and its cost. We also present a new synthetic route for deuterium-labeled polyamines. The LC-MS/MS method was rigorously validated by quantifying levels of nitrogen-related metabolites in seedlings of seven plant species, including Arabidopsis, maize, and barley, all of which are commonly used model organisms in plant science research. Our results revealed substantial variations in the abundance of these metabolites between species, developmental stages, and growth conditions, particularly for the acetylated and methylated derivatives and the various polyamine fractions. However, the biological relevance of these plant metabolites is currently unclear. Overall, this work contributes significantly to plant science by providing a powerful analytical tool and setting the stage for future investigations into the functions of these nitrogen-related metabolites in plants. Chemistry ; Metabolomics ; Nitrogen ; Metabolite ; Environmental chemistry ; Chromatography ; Biochemistry ; Organic chemistry Analytical Chemistry and Chromatography ; Metabolomics and Mass Spectrometry Studies ; Botanical Research and Chemistry
Authors: Vardan Galstyan | Ilenia D’Onofrio | Aris Liboà | Giuseppe De Giorgio | Davide Vurro | Luigi Rovati | Giuseppe Tarabella | Pasquale D’Angelo
Source: Advanced Materials Technologies (article, 2024-07-23)
Field: Materials Science — Polymers and Plastics

Recent Advances in Self‐Powered Electrochemical Biosensors for Early Diagnosis of Diseases Abstract Modern sensing technologies are highly required for health monitoring. In this respect, the development of small‐size, high‐performance, and self‐powered biosensors for detecting and quantifying disease markers in biofluids can bring crucial changes and improvements to the concept of health monitoring systems. Clinical trials identify a wide range of biomarkers in biofluids that provide significant health information. Research into novel functional materials with outstanding properties opens up new perspectives for fabricating new‐generation biosensors. Furthermore, energy conversion and storage units are investigated to integrate them into biosensors and develop self‐powered systems. Electrochemical methods are very attractive for applications in biosensor technology, both in terms of biomarker detection and energy generation. Here the recent achievements in research into self‐powered electrochemical biosensors to detect sweat and saliva biomarkers are presented. Potential biomarkers for efficient analysis of these fluids are discussed in light of their importance in identifying various diseases. The influence of electrode materials on the performance of sensors is discussed. Progress in developing operating strategies for self‐powered electrochemical monitoring systems is also discussed. A summary and outlook are presented, mentioning major achievements and current issues to be explored. Nanotechnology ; Biosensor ; Materials science ; Medicine Conducting polymers and applications ; Advanced Sensor and Energy Harvesting Materials ; Electrochemical sensors and biosensors