jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Qijun Sun | Si Liu | Ziping Li | Peiji Deng | Na Niu | Ligang Chen | Kang Liang
Source: Advanced Materials (review, 2025-07-02)
Field: Materials Science — Materials Chemistry

Spatial Coordination Structure‐Driven Enzyme‐Like Selectivity in Single‐Atom Nanozymes Single-atom nanozymes (SAzymes) are nanomaterials that rely on atomic-level active sites to efficiently express catalytic functions like natural enzymes. With their outstanding robustness and exceptional atomic utilization, they are among the most competitive nanozymes used to overcome the inherent shortcomings of natural enzymes. However, SAzymes lack the precise structural complexity of natural enzymes and therefore do not exhibit the same level of catalytic selectivity-a major barrier to fully replacing natural enzymes. Previous studies have primarily focused on summarizing the methods and rules for improving the enzyme-like activity of SAzymes, while comparatively little attention has been given to their catalytic selectivity. Herein, this work reviews recent progress in enhancing the enzyme-like catalytic selectivity of SAzymes through the rational design of their spatial coordination structures. It emphasizes the structure-activity relationships of various attributes of these coordination structures in promoting selective catalytic behavior, the strategic design of coordination structures for target enzyme-like reactions, and effective synthesis methods for integrating these structures onto supports. In addition, the development prospects and current challenges in exploring SAzyme coordination structures are analyzed to provide new inspiration constructing next generation, highly selective SAzymes. Selectivity ; Nanotechnology ; Catalysis ; Rational design ; Robustness (evolution) ; Materials science ; Nanomaterials ; Biochemical engineering ; Combinatorial chemistry ; Chemistry ; Engineering ; Organic chemistry ; Gene ; Biochemistry Advanced Nanomaterials in Catalysis ; Nanocluster Synthesis and Applications ; Advanced biosensing and bioanalysis techniques
Authors: Gomaa F Elfawal | Alena Opálková Šišková | Anita Eckstein Andicsová
Source: Fibers and Polymers (article, 2025-07-31)
Field: Materials Science — Biomaterials

Electrospinning: A Game-Changer in Fiber Production and Practical Applications Abstract Electrospinning is a simple, flexible, cost-effective, and efficient method for continuously producing micro- and nanoscale polymer fibers. This process has garnered significant attention from both scientific and industrial communities for its ability to create nanofibers with a large specific surface area, flexibility, and customizable properties. The electrospinning process encompasses a range of principles, techniques, and influencing factors that significantly impact the production of nanofibers. This versatility renders electrospinning a highly practical method for various applications, including sensors, biomedical solutions, energy technologies, food packaging, and filtration systems. Unlike other literature on the subject, this review takes a comprehensive approach that combines basic principles with practical applications. Overall, electrospinning holds great promise for a wide range of applications due to its efficiency in producing microfibers and nanofibers with tailored properties. Materials science ; Electrospinning ; Production (economics) ; Fiber ; Nanofiber ; Composite material ; Nanotechnology ; Process engineering ; Polymer Electrospun Nanofibers in Biomedical Applications ; Advanced Sensor and Energy Harvesting Materials ; Supercapacitor Materials and Fabrication
Authors: Sijie Zhang | Ran Xu | Shao‐Bin He | Rong Sun | Guannan Wang | Shuyi Wei | Xiyun Yan | Kelong Fan
Source: Military Medical Research (review, 2025-05-30)
Field: Materials Science — Materials Chemistry

Nanozyme-driven multifunctional dressings: moving beyond enzyme-like catalysis in chronic wound treatment The treatment of chronic wounds presents significant challenges due to the necessity of accelerating healing within complex microenvironments characterized by persistent inflammation and biochemical imbalances. Factors such as bacterial infections, hyperglycemia, and oxidative stress disrupt cellular functions and impair angiogenesis, substantially delaying wound repair. Nanozymes, which are engineered nanoscale materials with enzyme-like activities, offer distinct advantages over conventional enzymes and traditional nanomaterials, making them promising candidates for chronic wound treatment. To enhance their clinical potential, nanozyme-based catalytic systems are currently being optimized through formulation advancements and preclinical studies assessing their biocompatibility, anti-oxidant activity, antibacterial efficacy, and tissue repair capabilities, ensuring their safety and clinical applicability. When integrated into multifunctional wound dressings, nanozymes modulate reactive oxygen species levels, promote tissue regeneration, and simultaneously combat infections and oxidative damage, extending beyond conventional enzyme-like catalysis in chronic wound treatment. The customizable architectures of nanozymes enable precise therapeutic applications, enhancing their effectiveness in managing complex wound conditions. This review provides a comprehensive analysis of the incorporation of nanozymes into wound dressings, detailing fabrication methods and emphasizing their transformative potential in chronic wound management. By identifying and addressing key limitations, we introduce strategic advancements to drive the development of nanozyme-driven dressings, paving the way for next-generation chronic wound treatments. Medicine ; Wound healing ; Regeneration (biology) ; Chronic wound ; Nanotechnology ; Surgery ; Materials science ; Cell biology ; Biology Advanced Nanomaterials in Catalysis ; Graphene and Nanomaterials Applications ; Nanoplatforms for cancer theranostics
Authors: Andrea Pizzi | Giancarlo Terraneo | Cristina Lo Iacono | Roberta Beccaria | Arun Dhaka | Giuseppe Resnati
Source: Angewandte Chemie International Edition (article, 2025-05-22)
Field: Chemistry — Physical and Theoretical Chemistry

Taxonomy of Chemical Bondings: Opportunities and Challenges The concept of the chemical bond is fundamental to chemistry, governing atomic interactions that define all known matter. Despite this central role, the classification and most convenient naming of chemical bonds remain subjects of debate due to the diverse theoretical models and experimental observations. Modelings from quantum mechanical calculations and heuristic principles from experimental observations offer valuable and complementary insights, but sometimes the match and coalescence of these different approaches into a common terminology is not immediate. This paper describes a hierarchical categorization of noncovalent interactions based on the electrophilic atom involved, aligning with IUPAC definitions of hydrogen bonding (HB), halogen bonding (HaB), chalcogen bonding (ChB), and pnictogen bonding (PnB). The resulting taxonomy may avoid some ambiguities that arise from naming interactions based on single chemical/physical features. The proposed categorization that moves from more general and comprehensive terms to more specific and descriptive terms may ensure clarity, comprehensiveness, consistency with periodic trends, and invariancy over evolving understanding of the chemical bonds so that findings can be communicated and stored effectively via both human and machine based protocols. Categorization ; Terminology ; CLARITY ; Axiom ; Computer science ; Non-covalent interactions ; Taxonomy (biology) ; Quantum chemical ; Chemical bond ; Hydrogen bond ; Chemistry ; Artificial intelligence ; Biology ; Mathematics ; Molecule Crystallography and molecular interactions ; Computational Drug Discovery Methods ; Chemical Thermodynamics and Molecular Structure
Authors: Thibault Frippiat | Tatiana Art | Catherine Delguste
Source: Nanomaterials (review, 2025-01-27)
Field: Materials Science — Materials Chemistry

Silver Nanoparticles as Antimicrobial Agents in Veterinary Medicine: Current Applications and Future Perspectives Silver nanoparticles (AgNPs) have gained significant attention in veterinary medicine due to their antimicrobial properties and potential therapeutic applications. Silver has long been recognized for its ability to combat a wide range of pathogens, and when engineered at the nanoscale, silver's surface area and reactivity are greatly enhanced, making it highly effective against bacteria, viruses, and fungi. This narrative review aimed to summarize the evidence on the antimicrobial properties of AgNPs and their current and potential clinical applications in veterinary medicine. The antimicrobial action of AgNPs involves several mechanisms, including, among others, the release of silver ions, disruption of cell membranes and envelopes, induction of oxidative stress, inhibition of pathogens' replication, and DNA damage. Their size, shape, surface charge, and concentration influence their efficacy against bacteria, viruses, and fungi. As a result, the use of AgNPs has been explored in animals for infection prevention and treatment in some areas, such as wound care, coating of surgical implants, animal reproduction, and airway infections. They have also shown promise in preventing biofilm formation, a major challenge in treating chronic bacterial infections. Additionally, AgNPs have been studied for their potential use in animal feed as a supplement to enhance animal health and growth. Research suggested that AgNPs could stimulate immune responses and improve the gut microbiota of livestock, potentially reducing the need for antibiotics in animal husbandry. Despite their promising applications, further research is necessary to fully understand the safety, efficacy, and long-term effects of AgNPs on animals, humans, and the environment. Antimicrobial ; Silver nanoparticle ; Antibiotics ; Modern medicine ; Animal health ; Medicine ; Nanotechnology ; Biology ; Microbiology ; Biotechnology ; Veterinary medicine ; Intensive care medicine ; Materials science ; Nanoparticle Nanoparticles: synthesis and applications ; Moringa oleifera research and applications
Authors: Wenxin Wang | Chenghui Wu | Zonglin Li | Kai Liu
Source: Advanced Materials (review, 2025-02-17)
Field: Materials Science — Materials Chemistry

Interface Engineering of 2D Materials toward High‐Temperature Electronic Devices High-temperature electronic materials and devices are highly sought after for advanced applications in aerospace, high-speed automobiles, and deep-well drilling, where active or passive cooling mechanisms are either insufficient or impractical. 2D materials (2DMs) represent promising alternatives to traditional silicon and wide-bandgap semiconductors (WBG) for nanoscale electronic devices operating under high-temperature conditions. The development of robust interfaces is essential for ensuring that 2DMs and their devices achieve high performance and maintain stability when subjected to elevated temperatures. This review summarizes recent advancements in the interface engineering of 2DMs for high-temperature electronic devices. Initially, the limitations of conventional silicon-based materials and WBG semiconductors, alongside the advantages offered by 2DMs, are examined. Subsequently, strategies for interface engineering to enhance the stability of 2DMs and the performance of their devices are detailed. Furthermore, various interface-engineered 2D high-temperature devices, including transistors, optoelectronic devices, sensors, memristors, and neuromorphic devices, are reviewed. Finally, a forward-looking perspective on future 2D high-temperature electronics is presented. This review offers valuable insights into emerging 2DMs and their applications in high-temperature environments from both fundamental and practical perspectives. Materials science ; Electronics ; Interface (matter) ; Engineering physics ; Transistor ; Nanotechnology ; Neuromorphic engineering ; Silicon ; Semiconductor ; Electronic materials ; Semiconductor device ; Optoelectronics ; Electrical engineering ; Computer science ; Engineering 2D Materials and Applications ; MXene and MAX Phase Materials ; Graphene research and applications
Authors: Xingyue Wang | Na Tian | L. He | Zhixiang Yuan | Lu Han
Source: International Journal of Nanomedicine (review, 2025-05-01)
Field: Materials Science — Materials Chemistry

Emerging Applications of Pickering Emulsions in Pharmaceutical Formulations: A Comprehensive Review Over the past two decades, particle-stabilized Pickering emulsions (PEs) have emerged as a versatile platform in pharmaceutical formulations, demonstrating distinct advantages over surfactant-based systems through enhanced stability, reduced toxicity, and tunable interfacial properties. These systems exhibit unique drug delivery potential through their precisely controllable architecture, particularly in achieving spatiotemporal drug release patterns, tissue-specific targeting, and enhanced therapeutic payload encapsulation. In this review, the characteristics of PEs are first detailed, followed by an introduction to the main preparation methods and the key parameters for controlling the type, droplet size, and stability of PEs. The third section categorizes and discusses the advantages and disadvantages of various solid particles as emulsifiers. Lastly, emphasis is placed on the application of PEs in the pharmaceutical field, including functionalized designs and various administration routes to enlighten the rational design of PEs for effective drug delivery. Pickering emulsion ; Materials science ; Nanotechnology ; Nanoparticle Pickering emulsions and particle stabilization ; Proteins in Food Systems ; Surfactants and Colloidal Systems
Authors: Rajeswari Saripilli | Dinesh Kumar Sharma
Source: Discover Oncology (review, 2025-03-29)
Field: Materials Science — Biomaterials

Nanotechnology-based drug delivery system for the diagnosis and treatment of ovarian cancer Current research in nanotechnology is improving or developing novel applications that could improve disease diagnosis or treatment. This study highlights several nanoscale drug delivery technologies, such as nano micelles, nanocapsules, nanoparticles, liposomes, branching dendrimers, and nanostructured lipid formulations for the targeted therapy of ovarian cancer (OC), to overcome the limitations of traditional delivery. Because traditional drug delivery to malignant cells has intrinsic flaws, new nanotechnological-based treatments have been developed to address these conditions. Ovarian cancer is the most common gynecological cancer and has a higher death rate because of its late diagnosis and recurrence. This review emphasizes the discipline of medical nanotechnology, which has made great strides in recent years to solve current issues and enhance the detection and treatment of many diseases, including cancer. This system has the potential to provide real-time monitoring and diagnostics for ovarian cancer treatment, as well as simultaneous delivery of therapeutic agents. Ovarian cancer ; Drug delivery ; Nanotechnology ; Targeted drug delivery ; Nanocapsules ; Medicine ; Cancer therapy ; Nanomedicine ; Cancer ; Materials science ; Internal medicine ; Nanoparticle Nanoparticle-Based Drug Delivery ; RNA Interference and Gene Delivery ; Extracellular vesicles in disease
Authors: Xiaoyang Liu | Huihui Zhang | Lianglong Chen | Zesen Zheng | Wenwen Li | Chaoyang Huang | Hai Zhou | Ying-Cheng Chen | Ziwei Jiang | Jian Liang | Qiuyi Yu | Lei Yang
Source: Journal of Nanobiotechnology (review, 2025-07-01)
Field: Materials Science — Materials Chemistry

Advanced wound healing with Stimuli-Responsive nanozymes: mechanisms, design and applications Wound healing outcomes critically depend on precise regulation of oxidative and antimicrobial microenvironments. Traditional dressings have limited wound responsiveness, insufficient infection control, and limited treatment accuracy. In contrast, nanozymes, featuring enzyme-mimetic activities, tunable catalysis, and engineered sizes that balance catalytic site accessibility with tissue penetration, offer spatiotemporal control of reactive oxygen species (ROS) and pathogen elimination. This review systematically examines recent advances in stimuli-responsive nanozymes for wound management, focusing on their catalytic mechanisms and therapeutic specificity. These intelligent systems dynamically adapt catalytic behaviors (e.g., ROS scavenging, bacterial lysis) to physical stimuli (temperature, light, ultrasound) and physiological signals (pH, redox imbalance, ATP levels, microbial metabolites), leveraging size-dependent targeting mechanisms to ensure localized therapeutic effects while minimizing off-target damage. Current evidence demonstrates their multifunctional capacity to synergistically accelerate infection clearance, inflammation resolution, and angiogenesis. Future development should prioritize biosafety validation alongside size-effect standardization, stimulus specificity, and scalable manufacturing to advance personalized nanomedicine for refractory wounds. Nanomedicine ; Reactive oxygen species ; Nanotechnology ; Wound healing ; Chemistry ; Medicine ; Nanoparticle ; Materials science ; Immunology ; Biochemistry Advanced Nanomaterials in Catalysis ; Nanoplatforms for cancer theranostics ; Graphene and Nanomaterials Applications
Authors: Rashid Dallaev
Source: Polymers (review, 2025-08-29)
Field: Materials Science — Polymers and Plastics

Conductive Polymer Thin Films for Energy Storage and Conversion: Supercapacitors, Batteries, and Solar Cells Conductive polymer thin films have emerged as a versatile class of materials with immense potential in energy storage and conversion technologies due to their unique combination of electrical conductivity, mechanical flexibility, and tunable physicochemical properties. This review comprehensively explores the role of conductive polymer thin films in three critical energy applications: supercapacitors, batteries, and solar cells. The paper examines key polymers such as polyaniline (PANI), polypyrrole (PPy), and poly(3,4-ethylenedioxythiophene) (PEDOT), focusing on their synthesis techniques, structural modifications, and integration strategies to enhance device performance. Recent advances in film fabrication methods, including solution processing, electrochemical deposition, and layer-by-layer assembly, are discussed with regard to achieving optimized morphology, conductivity, and electrochemical stability. Furthermore, the review highlights current challenges such as scalability, long-term durability, and interfacial compatibility, while outlining future directions for the development of high-performance, sustainable energy systems based on conductive polymer thin films. Supercapacitor ; Materials science ; Energy storage ; Electrical conductor ; Conductive polymer ; Polymer ; Solar energy ; Composite material ; Electrical engineering ; Capacitance ; Electrode ; Chemistry ; Engineering ; Physics Conducting polymers and applications ; Supercapacitor Materials and Fabrication ; Advanced Sensor and Energy Harvesting Materials
Authors: Patricia Quintero-Rincón | Karina Caballero-Gallardo | Jesús Olivero‐Verbel
Source: Natural Products and Bioprospecting (review, 2025-04-21)
Field: Chemistry — Organic Chemistry

Natural anticancer agents: prospection of medicinal and aromatic plants in modern chemoprevention and chemotherapy Natural products obtained from medicinal and aromatic plants are increasingly recognized as promising anticancer agents due to their structural richness, including terpene and flavonoid molecules, which induce apoptosis and modulate gene expression. These compounds offer an alternative to conventional treatments, often costly, which face challenges such as multidrug resistance. This review aims to provide a promising alternative approach to effectively control cancer by consolidating significant findings in identifying natural products and anticancer agent development from medicinal and aromatic plants. It synthesizes the findings of a comprehensive search of academic databases, such as PubMed and Springer, prioritizing articles published in recognized peer-reviewed journals that address the bioprospecting of medicinal and aromatic plants as anticancer agents. The review addresses the anticancer activities of plant extracts and essential oils, which were selected for their relevance to chemoprevention and chemotherapy. Compounds successfully used in cancer therapy include Docetaxel (an antimitotic agent), Etoposide VP-16 (an antimitotic agent and topoisomerase II inhibitor), Topotecan (a topoisomerase I inhibitor), Thymoquinone (a Reactive Oxygen Species-ROS inducer), and Phenethyl isothiocyanate (with multiple mechanisms). The review highlights natural products such as Hinokitiol, Mahanine, Hesperetin, Borneol, Carvacrol, Eugenol, Epigallocatechin gallate, and Capsaicin for their demonstrated efficacy against multiple cancer types, including breast, cervical, gastric, colorectal, pancreatic, lung, prostate, and skin cancer. Finally, it highlights the need for continued bioprospecting studies to identify novel natural products that can be successfully used in modern chemoprevention and chemotherapy. Topotecan ; Pharmacology ; Natural product ; Docetaxel ; Traditional medicine ; Chemistry ; Cancer ; Biology ; Medicine ; Chemotherapy ; Biochemistry Synthesis and biological activity ; Bioactive Compounds and Antitumor Agents ; Nigella sativa pharmacological applications
Authors: V. Ramkumar | A. Bharathi | Mayakrishnan Gopiraman | Seong‐Cheol Kim
Source: Energies (article, 2025-03-04)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Advancements in Metal-Ion Capacitors: Bridging Energy and Power Density for Next-Generation Energy Storage Metal-ion capacitors (MICs) have emerged as advanced hybrid energy storage devices that combine the high energy density of batteries with the superior power density and long cycle life of supercapacitors. By leveraging a unique configuration of faradaic and non-faradaic energy storage mechanisms, MICs offer a balanced performance that meets the diverse requirements of modern applications, including renewable energy systems, electric vehicles, and portable electronics. MICs employ diverse ions such as lithium, sodium, and potassium, which provide flexibility in material selection, scalability, and cost-effectiveness. For instance, lithium-ion capacitors (LICs) excel in compact and high-performance applications, while sodium-ion (NICs) and potassium-ion capacitors (KICs) provide sustainable and affordable solutions for large-scale energy storage. This review highlights the advancements in electrode materials, including carbon-based materials, transition metal oxides, and emerging candidates like MXenes and metal–organic frameworks (MOFs), which enhance MIC performance. The role of electrolytes, ranging from organic and aqueous to hybrid and solid-state systems, is also examined, emphasizing their influence on energy density, safety, and operating voltage. Additionally, the article discusses the environmental and economic benefits of MICs, including the use of earth-abundant materials and bio-derived carbons, which align with global sustainability goals. The review concludes with an analysis of practical applications, commercialization challenges, and future research directions, including AI-driven material discovery and integration into decentralized energy systems. As versatile and transformative energy storage devices, MICs are poised to play a critical role in advancing sustainable and efficient energy solutions for the future. Bridging (networking) ; Energy storage ; Capacitor ; Energy density ; Supercapacitor ; Power density ; Materials science ; Electrical engineering ; Engineering physics ; Nanotechnology ; Power (physics) ; Engineering ; Computer science ; Chemistry ; Voltage ; Physics ; Capacitance ; Electrode ; Thermodynamics Supercapacitor Materials and Fabrication ; Advancements in Battery Materials ; Advanced battery technologies research