jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Liubomyr Havryshchuk | V. Ya. Horishny | Н. И. Рущак | Roman Lesyk
Source: ScienceRise Pharmaceutical Science (article, 2024-02-29)
Field: Chemistry — Organic Chemistry

Dichloroacetic acid derivatives as potential anti-tumor and anti-inflammatory agents The aim. This review aims to provide a comprehensive understanding of dichloroacetic acid derivatives. We aim to cover all aspects of these compounds, including their chemical properties, various synthesis methods, and their wide range of applications in medicinal chemistry. By exploring their diverse roles in drug development, we aim to highlight their importance and potential in shaping future pharmaceutical innovation. Materials and methods. Bibliosemantic and analytical methods are used in the research. Results. Our studies confirm the potential effectiveness of dichloroacetic acid and its derivatives in the treatment of cancer and other diseases. These compounds can induce the apoptosis process, which is the programmed cell death, and inhibit the cancer cells' growth. This is particularly effective when dichloroacetic acid and its derivatives are used in combination with other therapeutic methods, as indicated in the patents cited in our study. Dichloroacetic acid and its derivatives have also shown the ability to lower blood glucose and cholesterol levels. This indicates the possibility of their use for diabetes, hyperlipidemia, and lactic acidosis treatment. Diabetes, hyperlipidemia, and lactic acidosis are serious conditions that can lead to significant health problems. Therefore, the possibility of using dichloroacetic acid and its derivatives for the treatment of these conditions opens new perspectives in medical science. Conclusions. Our findings point to the prospects of further research in the field of new therapy methods development and the use of dichloroacetic acid derivatives as potential drugs to improve the effectiveness of cancer and other diseases treatment. We believe that these compounds have great potential for further study and may play an important role in future medical innovation Dichloroacetic acid ; Hyperlipidemia ; Pharmacology ; Chemistry ; Medicine ; Diabetes mellitus ; Biochemistry ; Endocrinology Free Radicals and Antioxidants ; Synthesis and biological activity ; Scientific Research and Studies
Authors: Abbaraju Krishna Sailaja
Source: Pharmaceutics and Pharmacology Research (article, 2024-02-29)
Field: Materials Science — Biomaterials

Nanoparticles: An Advanced Drug Delivery System for Drug Targeting The current article sites the importance of the emerging and promising future of new dosage form, nanoparticles. In recent years biodegradable nanoparticles are gaining attention as therapeutic strategies for epilepsy management. NP can cross the BBB improve selectivity to the brain decreasing side effects, and offer a sustained drug delivery. Biodegradable nanomaterials can be naturally degraded in non-toxic bioproducts in body and can be designed for their degradation once arrived to target site while remaining are stable at off- target places. The two main types of biodegradable NP will be summarised in the following sections along with their applications for epilepsy treatment. Targeted drug delivery ; Drug ; Drug delivery ; Bioproducts ; Epilepsy Nanoparticle-Based Drug Delivery ; Advanced Drug Delivery Systems ; Cancer Research and Treatment
Authors: Kai Sun | Yoshito Heike | Masaya Sawamura | Chung‐Yang Huang | Y. Shimizu
Source: ChemRxiv (preprint, 2024-09-03)
Field: Chemistry — Organic Chemistry

Photoinduced Boron-Catalyzed β-Allylation of Carboxylic Acids Enabled by a Mixed Two-Ligand System A visible light-induced, boron-catalyzed direct β-allylation of carboxylic acids with allylsulfones was developed. The selective promotion of β-allylation over the competing α-allylation was achieved by the combined use of a bulky binaphthol derivative and a N-sulfonyl valine derivative as ligands for the boron catalyst. Photoexcitation of catalytically generated diboron ene-1,1-diolates induces single-electron transfer to the allylsulfones, and ensuing deprotonation of the resulting radical cations generates β-radicals, directing C–C bond formation at the β-position. The versatility of this catalysis was demonstrated through its application to various pharmaceutical compounds. Furthermore, by leveraging the unique features of the carboxy group preserved in the products, subsequent transformations were successfully achieved, showcasing the capability of the boron catalysis in rapidly increasing the molecular complexity of carboxylic acids. Catalysis ; Boron ; Ligand (biochemistry) ; Chemistry ; Carboxylic acid ; Combinatorial chemistry ; Photochemistry ; Organic chemistry ; Biochemistry Radical Photochemical Reactions ; Catalytic C–H Functionalization Methods ; Chemical Synthesis and Reactions
Authors: S.S. Uderbayev | Kylyshbay Bissenov | Roza Narmanova | К.А. Yerimbetov | Nurzhamal Sailaubekova
Source: Civil Engineering and Architecture (article, 2024-12-05)
Field: Chemistry — Analytical Chemistry

Rheological Properties of Asphalt Concrete based on Asphalt-resin and Paraffin Deposits of Oil Fields and Ash of Thermal Energy Central of Kazakhstan The research is devoted to the study of the possibility of using asphalt resin-paraffin residues and ash from thermal power plants in the production of asphalt concrete to improve its performance and reduce environmental impact. The study employed samples of asphalt-resin-paraffin deposits from oil fields in the Kyzylorda region, infrared spectroscopy and gas chromatography-mass spectrometry to determine the specific surface area and activity of natural radionuclides in the ash from the Kyzylorda thermal power plant. The main results of the study show that fly ash from thermal power plants contains a high content of silicon oxide (30.03-62.53%) and aluminium oxide (8.84-30.92%). Spectral analysis of asphalt-resin-paraffin residues from oil fields revealed the presence of hydrocarbons in methyl and methylene groups. The optimum composition of the composite binder “Bitumen – asphalt resin-paraffin residues – thermal power plant ash” is as follows: bitumen – 80-82%, thermal power plant ash – 7-11%, asphalt resin-paraffin residues – 8.5-9.5%. The resulting asphalt concrete demonstrated high compressive strength (2.2-2.5 MPa at 50℃, 4.4-5.2 MPa at 20℃, 9.7-9.9 MPa at 0℃), high shear stability (internal friction coefficient 0.85-0.87), excellent shear adhesion at 50℃ (0.62-0.86), high water resistance (0.89-0.98) and low water saturation (1.22-2.2%). The results also show that the use of thermal power plant ash and asphalt resin-paraffin residues in asphalt concrete improves its performance and reduces the environmental impact through waste recycling. The data obtained confirm the possibility of effective use of these materials in road construction in Central Kazakhstan. This research brings to science a practical methodology for developing asphalt concrete composition using asphalt resin-paraffin residues and ash from thermal power plants, which contributes to the efficient use of resources and reduction of environmental impact in road construction. Asphalt ; Rheology ; Materials science ; Asphalt concrete ; Composite material ; Asphalt pavement ; Geotechnical engineering ; Thermal ; Waste management ; Environmental science ; Geology ; Engineering Petroleum Processing and Analysis ; Coal Combustion and Slurry Processing ; Drilling and Well Engineering
Authors: Loredana Schiavo | Lucrezia Aversa | Roberto Verucchi | Rachele Castaldo | Gennaro Gentile | G. Carotenuto
Source: Preprints.org (preprint, 2024-03-04)
Field: Materials Science — Materials Chemistry

Negative Temperature Coefficient Properties of Natural Clinoptilolite Electronic negative temperature coefficient (NTC) materials are usually based on ceramic semiconductors. A new type of NTC-material is represented by zeolites. Indeed, zeolites are single-charge carrier ionic conductors with a temperature-dependent electrical conductivity. In particular, electrical transport in zeolite is due to the monovalent charge-balancing cations, like K+, capable of hopping between negatively charged sites in the silico-aluminate framework. Owing to the highly non-linear electrical behavior of the traditional electronic NTC-materials, the possibility to have alternative types of materials, showing linearity in the electrical behavior, is very desirable. Among different zeolites, the natural clinoptilolite has been selected for investigating the NTC behavior since it is characterized by high zeolite content, convenient Si/Al atomic ratio, good mechanical strength, due to its compact microstructure, and low toxicity. Clinoptilolite has shown a rapid and fully reversible impedance change with heating, characterized by a linear dependence on temperature. The X-ray photoelectron spectroscopy (XPS) analysis has been used for the chemical characterization of the natural clinoptilolite sample as it provides important information on the cationic content and framework composition. In addition, since electrical transport takes place in the free-volume of zeolite, the Brunauer&amp;ndash;Emmett&amp;ndash;Teller (BET) analysis has been also provided. Clinoptilolite ; Natural (archaeology) ; Environmental science ; Chemistry ; Geology ; Zeolite Thermal and Kinetic Analysis ; thermodynamics and calorimetric analyses ; Chemical Thermodynamics and Molecular Structure
Authors: Loredana Schiavo | Lucrezia Aversa | Roberto Verucchi | Rachele Castaldo | Gennaro Gentile | G. Carotenuto
Source: Preprints.org (preprint, 2024-03-18)
Field: Materials Science — Materials Chemistry

Negative Temperature Coefficient Properties of Natural Clinoptilolite Negative temperature coefficient (NTC) materials are usually based on ceramic semiconductors and electrons are involved in their transport mechanism. A new type of NTC material, adequate for alternating current (AC) applications, is represented by zeolites. Indeed, zeolites are single-charge carrier ionic conductors with a temperature-dependent electrical conductivity. In particular, electrical transport in zeolites is due to the monovalent charge-balancing cations, like K+, capable of hopping between negatively charged sites in the aluminosilicate framework. Owing to the highly non-linear electrical behavior of the traditional electronic NTC materials, the possibility to have alternative types of materials, showing linearity in the electrical behavior, is very desirable. Among different zeolites, the natural clinoptilolite has been selected for investigating the NTC behavior since it is characterized by high zeolite content, convenient Si/Al atomic ratio, good mechanical strength, due to its compact microstructure, and low toxicity. Clinoptilolite has shown a rapid and quite reversible impedance change under heating, characterized by a linear dependence on temperature. X-ray diffraction (XRD) has been used to identify the natural zeolite, to establish all types of crystalline phases present in the mineral, and to investigate the thermal stability of these phases up to 150&amp;deg;C. X-ray photoelectron spectroscopy (XPS) analysis has been used for the chemical characterization of the natural clinoptilolite sample, providing important information on the cationic content and framework composition. In addition, since electrical transport takes place in the zeolite free-volume, a Brunauer&amp;ndash;Emmett&amp;ndash;Teller (BET) analysis of the mineral has been also performed. Clinoptilolite ; Natural (archaeology) ; Temperature coefficient ; Materials science ; Environmental science ; Chemistry ; Geology ; Zeolite ; Composite material ; Organic chemistry Thermal and Kinetic Analysis ; thermodynamics and calorimetric analyses ; Chemical Thermodynamics and Molecular Structure
Authors: Hipólito Carbajal-Morán | Carlos Abel Galvan Maldonado | Javier Francisco Márquez Camarena
Source: Ecological Engineering & Environmental Technology (article, 2024-01-27)
Field: Chemistry — Analytical Chemistry

Characterization of Metallic Gold Nanoparticles in a Colloidal State by Artificial Vision Gold nanoparticles in their colloidal state have different colors, and the equipment for their characterization, such as UV-Vis spectrophotometers, scanning electron microscopy (SEM), and transmission electron microscopy (TEM), has high costs. The research aimed to characterize metallic gold nanoparticles by artificial vision based on the color of the samples in the colloidal state. The sensor used for the sampling was a 50 MP triple-lens camera with the optical image stabilization (OIS) of a smartphone. The Vision Acquisition and Vision Assistant blocks in the NI LabVIEW platform were used to implement an artificial vision device. The camera interface was used to identify the color of each of the 10 samples of colloidal gold nanoparticles produced by the YAG laser and chemical reduction in 15 ml of deionized water. The characterization consisted of the determination of the size and concentration of the gold nanoparticles based on their color, which ranged from pink to red wine. As a result, the artificial vision device adequately identified the color of the metallic gold nanoparticles in a colloidal state with a certainty of more than 95%, allowing the nanoparticles to be adequately characterized. Therefore, it is concluded that artificial vision adequately characterized gold nanoparticles' wavelength, absorbance, diameter, and concentration. Colloidal gold ; Characterization (materials science) ; Nanotechnology ; Nanoparticle ; Materials science ; Artificial intelligence ; Computer science Spectroscopy and Chemometric Analyses ; Digital Imaging for Blood Diseases ; Water Quality Monitoring and Analysis
Authors: K. Karthik | Vinayagamoorthy Munusamy | Senthilkumar Nangan | Ramesh MD | Muhamed Hussain | K.P. Singh
Source: E3S Web of Conferences (article, 2024-01-01)
Field: Materials Science — Polymers and Plastics

Study on the effect of CuO influenced kenaf fiber reinforced epoxy composite – A novel material for secondary structural applications This study investigates the effects of copper oxide (CuO) particles on the mechanical and thermal properties of kenaf fibre reinforced epoxy composites, suggesting a new material suitable for structural applications. Comprehensive tests, including Thermogravimetric Investigation (TGA), weakness testing, and Checking Electron Microscopy (SEM), were conducted to evaluate the performance enhancements provided by the incorporation of CuO. The TGA has revealed that CuO particles significantly enhance the thermal stability of the composites. Among the many tests, sample C (6g of CuO) has the highest thermal resistance, retaining 17% of its weight at 500°C, which is higher than the other tests. The fatigue testing demonstrated that the composites exhibited remarkable fatigue resistance, particularly Test C, which maintained a fatigue stress of 14 MPa even after 15,000 cycles, indicating superior durability under cyclic loading circumstances. The SEM study revealed detailed microstructural observations, showing a consistent distribution of CuO particles and strong bonding between the fibres and matrix, which enhance the mechanical performance and resistance to failure. Kenaf ; Epoxy ; Composite material ; Composite number ; Materials science ; Fiber Natural Fiber Reinforced Composites ; Nanocomposite Films for Food Packaging ; Polymer composites and self-healing
Authors: Ranjini Devi Rama | Abdul Rafeq Saleman | Muhamad Shukri Zakaria | Mohd Afzanizam Mohd Rosli | Bukhari Manshoor
Source: Journal of Advanced Research in Applied Mechanics (article, 2024-08-30)
Field: Chemistry — Physical and Theoretical Chemistry

Orientation of Linear Liquid Alkane on Solid Surface of Face Centered Cubic Lattice of (100), (110) and (111) Solid-liquid (S-L) interfaces are found in numerous engineering applications, such as lubrication and coating systems as well as thermal interface materials. Understanding the interactions between (S-L) is crucial for optimizing various engineering applications. The main objective of this study is to provide insight regarding liquid adsorption on solid surfaces using non-equilibrium molecular dynamics simulations. To achieve this goal, a liquid confined between solid surfaces will be modeled to match the real state of contact interfaces using a constant temperature as a baseline. The results highlight a significant relationship between the peak height values of the liquid adsorption layer, density profile, and radius of gyration. Specifically, the peak height density at the S-L interfaces for the crystal plane (110) is 784.756 kg/m3, followed by (100) at 801.786 kg/m3, and finally the highest is for the crystal plane (111), at 966.940 kg/m3. Whereas the radius of gyration at the S-L interfaces for crystal planes (100) and (111) is approximately 7.45 × 10-21 m2, but for crystal plane (110) it is less and measures approximately 7.06 × 10-21 m2. Conclusion, the adsorption layer of solid density near solid-liquid interfaces is significantly influenced by the peak height of the solid's density. Higher density results in a higher adsorption layer of liquid near solid-liquid interfaces. The number of solid density layers does not affect the height of adsorption layers for liquids. Cubic crystal system ; Lattice (music) ; Materials science ; Orientation (vector space) ; Alkane ; Condensed matter physics ; Solid surface ; Face (sociological concept) ; Crystallography ; Geometry ; Chemical physics ; Chemistry ; Physics ; Hydrocarbon ; Mathematics ; Organic chemistry Advanced Physical and Chemical Molecular Interactions ; Synthesis and properties of polymers ; Chemical Thermodynamics and Molecular Structure
Authors: Vishal Sharma | Mansi Nautiyal | Pavas Saini | Sahil Khurana | Venkat S. Charyulu | Anjali Vyas
Source: E3S Web of Conferences (article, 2024-01-01)
Field: Materials Science — Polymers and Plastics

Sustainable Energy Conversion via Organic Photovoltaics: Material Selection and Evaluation The lightweight, flexible, and cost-effective features of organic photovoltaics (OPVs) makes them a promising candidate for the development of a sustainable energy conversion technology. In this study, we investigate the process of selecting and evaluating organic materials for use in OPV applications, with a particular emphasis on improving both efficiency and stability. In this study, the most important results are highlighted by means of a complete literature review and data analysis. Bandgaps, HOMO levels, and LUMO levels are all features of the material that play a significant role in determining the performance of the device. Bandgaps may have values ranging from 1.6 to 2.2 eV, while HOMO levels can have values ranging from -5.5 to -4.8 eV. Efficiency enhancement initiatives, such as the invention of new donor- acceptor polymers and non-fullerene acceptors, have resulted to gains in power conversion efficiency (PCE), with values reaching 15%. These benefits have been achieved via the implementation of these tactics. Due to the fact that degradation processes have an effect on the performance of the device over time, stability concerns are very important for practical deployment. In order to improve the device's stability, encapsulation materials and stabilizing chemicals are used to reduce the number of breakdown routes. This paper contributes to the advancement of knowledge in OPV technology by highlighting the significance of material selection, efficiency enhancement, and stability improvement for sustainable energy conversion. Performance evaluation metrics, such as fill factor (FF) and open-circuit voltage (Voc), indicate improved device performance. FF ranges from 60% to 70%, and Voc ranges from 0.5 to 0.8 V. Overall, this paper contributes to the advancement of knowledge. The optimization of materials and device designs should be the primary focus of future research efforts in order to significantly improve the performance of OPVs and speed up its deployment as a viable renewable energy alternative. Organic solar cell ; Energy conversion efficiency ; Efficient energy use ; Materials science ; Process engineering ; Photovoltaics ; Nanotechnology ; Biochemical engineering ; Computer science ; Photovoltaic system ; Environmental science ; Polymer ; Electrical engineering ; Optoelectronics ; Engineering Conducting polymers and applications ; Organic Electronics and Photovoltaics ; Advanced battery technologies research
Authors: Glen Dickson
Source: Information Display (article, 2024-05-01)
Field: Materials Science — Materials Chemistry

The Evolving Impact of Quantum Dots on Displays Abstract Display insiders predict that QDs will continue to have a broad impact on the display industry for the next decade or more. Quantum dot ; Computer science ; Human–computer interaction ; Nanotechnology ; Business ; Materials science Quantum Dots Synthesis And Properties ; Green IT and Sustainability
Authors: Aman Sheji | Dawn Sivan | Rajan Jose
Source: Current Science and Technology (article, 2024-06-21)
Field: Chemistry — Physical and Theoretical Chemistry

Evolution of Graphene, Graphene Oxide, Reduced Graphene Oxide: An Exploratory Study Using Citation Network Analysis Graphene and its synthesis, along with its derivatives, have been at the forefront of materials’ research since its discovery in 2004. An analysis done during Dec 2023 using the keywords “graphene” and “synthesis” revealed nearly 40,000 research papers including journal articles, conference proceedings, reviews, books and book chapters; analysis of this vast data is beyond human abilities and requires computational intelligence. One of the research methodologies employed in analysing such vast data is Citation Network Analysis (CNA). Choosing the threshold citation to be two, the CNA constituted a cluster containing 294,680 papers. Using CNA, this study categorises this extensive literature into 12 clusters, unveiling their main paths of evolution. Notably, the most active research area focuses on the development of electrode materials for electrochemical applications. Additional focal points include advanced photocatalysts, electrocatalytic nitrogen fixation, wideband electromagnetic wave absorption materials, catalysts for formic acid oxidation, and flame retardancy in epoxy resin. The preference for the modified Hummers' method for synthesising graphene oxide emerges prominently due to its scalability. The implications of these findings are profound, paving the way for advancements in graphene synthesis with widespread impacts in industrial applications. By examining the historical trajectory of graphene research, this study offers critical insights, guiding future research endeavours in advanced materials science Graphene ; Oxide ; Graphene oxide paper ; Materials science ; Graphene nanoribbons ; Nanotechnology ; Metallurgy History and advancements in chemistry