jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Vishal Kumar | P Shinde | Neeraj Sharma | Mohan Lal Kolhe
Source: International Journal of Environmental Sciences (article, 2025-08-20)
Field: Materials Science — Materials Chemistry

Advancing Nuclear Technology for Clean Energy And Human Welfare: Innovations from Mineral to Medicine Background:In the face of escalating environmental challenges and rising global energy demands, nuclear technology has re-emerged as a vital solution for clean energy production. Simultaneously, its applications in healthcare and food safety have expanded significantly, contributing to human welfare in diverse ways. Aim or objective:This paper aims to explore the full spectrum of nuclear technology innovations, from mineral extraction to its applications in modern medicine and sustainable energy, while evaluating their implications for safety, efficiency, and human development. Methods:A qualitative research approach was adopted, utilizing thematic content analysis of peer-reviewed journals, policy reports, and case studies sourced from databases such as Scopus, Web of Science, and PubMed. The literature review focused on developments post-2000 to ensure contemporary relevance. Key results:The study found significant advancements in reactor design (including SMRs and Generation IV reactors), fuel cycle optimization, medical isotope applications, and nuclear waste management. It also identified improved safety protocols and growing acceptance of nuclear technology in non-energy sectors like medicine and agriculture. Conclusion:Nuclear technology continues to evolve from a singular focus on energy generation to a multidimensional tool that serves clean energy goals and public health needs. Responsible innovation, policy integration, and public engagement are essential for maximizing its benefits. Welfare ; Human welfare ; Mineral ; Clean energy ; Natural resource economics ; Energy (signal processing) ; Natural mineral ; Business ; Economics ; Chemistry ; Materials science ; Metallurgy ; Mineralogy ; Physics ; Market economy Graphite, nuclear technology, radiation studies ; Nuclear and radioactivity studies
Authors: Tawil Bill
Source:  (article, 2025-01-01)
Field: Materials Science — Biomaterials

Advances in Biomaterial Scaffolds for Spinal Cord Tissue Engineering SCI is a devastating condition characterized by the loss of motor, sensory, and autonomic function, with limited treatment options. This paper reviews the physiological architecture of the healthy spinal cord, the pathological mechanisms underlying spinal cord injury, and the current clinical landscape of mechanical and regenerative therapies. Market analysis reveals a growing demand for implantable, programmable, and biologically active solutions as populations age and long-term care costs continue to rise. Recent advances in scaffold design, stem cell therapies, neuromodulation, and hybrid technologies are driving innovation in both academic research and commercial development. Together, these trends point toward a future of personalized, multimodal regenerative medicine for spinal cord repair. Biomaterial ; Tissue engineering ; Spinal cord ; Biomedical engineering ; Medicine ; Neuroscience ; Biology Electrospun Nanofibers in Biomedical Applications ; Tissue Engineering and Regenerative Medicine
Authors: Mengyao Zhang | Yunren Yang | Guohua Gao | Zhenlong Li | Yakai He | Peigang Li | Huangzhen Lv
Source: Sensors (article, 2025-06-13)
Field: Chemistry — Analytical Chemistry

Research on Temperature Control Method of Rice Noodles Extruder Based on APSO-MPC Aiming to address the problems of many temperature control disturbances and the hysteresis of control output in existing rice noodle extruders, a temperature control method for a rice noodle extruder based on adaptive particle swarm optimization (APSO) optimization model predictive control (MPC) was designed. Firstly, the temperature control principle of the rice noodle extruder is analyzed by combining the structure of the rice noodle extruder. The temperature balance equation of the barrel is constructed by thermodynamic analysis, and the temperature prediction model is established. The APSO algorithm is further selected to perform the adaptive parameter identification of the model based on the collected input/output data. Then, aiming at high-precision temperature control, the objective function is constructed by combining the temperature prediction value and the reference trajectory, and the objective function is optimized to obtain the optimal control sequence. At the same time, the feed rate is selected as feedforward, the feed rate change is monitored by detecting the feed screw speed, and the optimal control sequence is corrected to eliminate the interference caused by the fluctuation of the feed rate. The experimental results show that the maximum temperature overshoot under different parameter combinations is 7.75%, the steady-state error is within ±1 °C, and the longest adjustment time is 1228 s. Compared with fuzzy PID control, it has stronger adaptability and higher control accuracy. Control theory (sociology) ; Plastics extrusion ; Temperature control ; Model predictive control ; Overshoot (microwave communication) ; Feed forward ; Particle swarm optimization ; Engineering ; PID controller ; Mathematics ; Computer science ; Control engineering ; Algorithm ; Materials science ; Control (management) Chromatography in Natural Products ; Advanced Control Systems Optimization
Authors: D.C. Vinna | C.A. Odilora | P. O. Okwuego | Prof. Rahane D. A.
Source: Journal of applied chemical science international (article, 2025-08-06)
Field: Chemistry — Organic Chemistry

Synthesis, Characterization and Solvatochromic Action of 4-Bromophenylazo-2-Naphtholazo-Benzene This study reveals the successful synthesis and comprehensive characterization of a novel disazo dye, 4-Bromophenylazo-2-Naphtholazo-Benzene, using accessible precursors through sequential diazotization and coupling reactions. The synthesis involved the diazotization of 4-bromoaniline and aniline, followed by stepwise coupling with 2-naphthol and benzene, yielding a maroon colored dye with high crystallinity and a melting point of 186 °C. Structural and functional analysis were conducted using UV-Visible spectrophotometry, Fourier Transform Infrared Spectroscopy (FTIR), Thin Layer Chromatography (TLC), Gas Chromatography-Mass Spectrometry (GC-MS), and elemental analysis. The UV-Vis spectrum revealed characteristic π–π* and n–π* transitions with absorption maxima up to 780 nm, attributed to the extended conjugation and presence of electron-withdrawing bromine substituents. FTIR spectra confirmed the presence of key functional groups such as azo (–N=N–) and aromatic C–Br, while GC-MS validated the compound’s molecular integrity through prominent base peaks. TLC analysis indicated moderate polarity (Rf = 0.76), and elemental composition corroborated the incorporation of bromine and nitrogen within the structure. The dye displayed excellent application potential, exhibiting high wash-, light-, and heat-fastness ratings (4–5) across a range of textile fibres including cotton, polyester, acrylic, and wool. These results highlight the compound’s chemical stability and suitability for commercial dyeing applications. Solvatochromism ; Benzene ; Characterization (materials science) ; Action (physics) ; Chemistry ; Materials science ; Organic chemistry ; Nanotechnology ; Physics ; Solvent Free Radicals and Antioxidants ; Photochemistry and Electron Transfer Studies ; Inorganic and Organometallic Chemistry
Authors: Andreea Ștefania Dumbravă | Viorica Maria Corbu | Ioana Cristina Marinaș | Radu Pericleanu | Liliana Marinescu | Ludmila Motelică | Doina Roxana Trusca | Nicoleta Ianovici | T. E. Şesan | Irina Gheorghe-Barbu | Denisa Ficai | Ovidiu Oprea | Anton Ficai | Mariana Carmen Chifiriuc
Source: Frontiers in Microbiology (article, 2025-08-22)
Field: Materials Science — Materials Chemistry

Multifunctional protective strategies for wooden cultural heritage: antimicrobial efficacy of polyacrylic resins, siloxane coupling agents, and silver nanoparticles The findings support the use of AgNP-enhanced polyacrylic resins and silanized coatings as effective, non-destructive conservation strategies for wooden heritage artifacts, offering durable protection against microbial deterioration while maintaining environmental safety. Polyacrylic acid ; Siloxane ; Silver nanoparticle ; Antimicrobial ; Nanoparticle ; Nanotechnology ; Materials science ; Coupling (piping) ; Cultural heritage ; Chemistry ; Organic chemistry ; Composite material ; Polymer ; Archaeology ; History Nanoparticles: synthesis and applications ; Microplastics and Plastic Pollution ; Antimicrobial agents and applications
Authors: Baiq Amelia Riyandari | Yupita Tri Rezeki | Yussi Pratiwi | Mega Fia Lestari
Source: Jurnal Kimia Riset (article, 2025-12-12)
Field: Materials Science — Biomaterials

The Effect of Incorporation of Moringa Oleifera Leaf Extract on Characteristics of Chitosan-Alginate Films for Active Packaging In this research, preparation of chitosan/alginate film incorporated with Moringa oleifera leaf extract (MOE) was successfully developed. These films were characterized using FTIR spectrophotometer to investigate interaction between chitosan-alginate and the extract. Physical characteristics of these films were also identified including thickness, water content, film solubility, and water vapor permeability (WVP). Film characterization showed that chitosan/alginate films with Moringa oleifera extract had been formed. Addition of crude extract of Moringa oleifera did not affect the thickness of films significantly. Addition of Moringa oleifera leaf extract at higher level concentration increased film solubility of films. Meanwhile, water content and water vapor permeability (WVP) decreased with higher concentration of extract. Antioxidant performance, measured using UV-Vis spectrophotometer, revealed that the film with the highest extract concentration achived the greatest radical scavenging activity (RSA), reaching 43.65% after 48 hours. Furthermore, the application of on grapes demonstrated the potential of chitosan-alginate films with Moringa oleifera extract as effective active packaging. Moringa ; Solubility ; Antioxidant ; Water activity ; Active packaging ; Aqueous solution ; Scavenging Nanocomposite Films for Food Packaging ; Postharvest Quality and Shelf Life Management ; Microencapsulation and Drying Processes
Authors: Hiroyuki Miyachi | Masaki Koshimizu | Masashi Suzuki
Source: Preprints.org (preprint, 2025-12-11)
Field: Chemistry — Organic Chemistry

On-DNA Platform Molecules Based on a Diazide Scaffold II: A Compact Diazide Platform Designed for Small-Molecule Drug Discovery Expanding the chemical diversity of DNA-encoded libraries (DELs) is crucial for identifying binders to emerging drug targets using DEL technology. In the present study, as part of our ongoing efforts to develop on-DNA diazide platforms (D-DAPs)—platform molecules possessing both aromatic and aliphatic azide groups on a single core reactive scaffold—we have designed and synthesized a new compact diazide platform, designated as a compact D-DAP (C-D-DAP). This molecule is based on a low-molecular-weight reactive scaffold, 3-azido-5-(azidomethyl)benzoic acid, to facilitate small-molecule drug discovery targeting enzymes and G protein-coupled receptors (GPCRs). Furthermore, we established two distinct stepwise warhead construction strategies that exploit the chemoselective transformations of the azide groups in the C-D-DAP, which exhibit different reactivities. In addition, four virtual DELs were generated based on stepwise warhead elaboration from the C-D-DAP scaffold. Comparative chemical diversity analysis against bioactive compounds from ChEMBL revealed that these virtual libraries populate structural regions that are sparsely represented among known molecules. Each virtual library also occupies a distinct region of structural space relative to the others and displays intermediate quantitative estimate of drug-likeness (QED) values. Chemical space ; chEMBL ; Drug discovery ; Azide ; Cheminformatics ; Moiety ; Small molecule Click Chemistry and Applications ; Chemical Synthesis and Analysis ; Protein Degradation and Inhibitors
Authors: Sofya Mikhailovna Terekhova | Alexander Ivannikov | Anton Abramov | Veronika Kirillova | Vladimir Mikhalchik | Alexander Bazhenov | Pavel Morokhov | Ivan Fedotov | Ivan Klyushin | Nikita Popov | Oleg Sevryukov
Source: Preprints.org (preprint, 2025-12-11)
Field: Materials Science — General Materials Science

Brazing Alloys Based on Ag-Cu System for Ceramic-Metal Joints Four compositions of rapidly quenched ribbon brazing alloys based on the Ag-Cu-Ti (Ag-26.5Cu-1.5Ti, Ag-25Cu-5Ti) and Ag-Cu-Zr (Ag-26.5Cu-1.5Zr, Ag-25Cu-5Zr) sys-tems were produced. Initial ingots were synthesized by arc melting. Rapidly solidified ribbons, 50-100 μm thick, were then fabricated from homogenized ingots using a &amp;quot;Crystall-702&amp;quot; facility. A comparative analysis of the microstructure and phase com-position of both the ingots and ribbons was conducted using scanning electron mi-croscopy and X-ray diffraction. The analysis revealed the presence of Cu4Ti and CuTi intermetallic compounds in the Ag-Cu-Ti alloys, and AgCu4Zr and Zr2Cu in the Ag-Cu-Zr alloys. Rapid quenching was found to produce metastable structures and significantly refine the intermetallic phases. Microhardness measurements of the ingot and ribbon states demonstrated a substantial influence of processing route on me-chanical properties. The tensile strength of the ingots was also evaluated. Wetting an-gles of the rapidly quenched alloy melts on 99% Al2O3 (alumina) ceramic substrates under vacuum were determined. All produced ribbons, except for the Ag-26.5Cu-1.5Zr composition, demonstrated adequate wettability. Thus, these materials are considered promising for further research into heat-resistant metal-ceramic joints. Ingot ; Intermetallic ; Brazing ; Microstructure ; Alloy ; Ribbon ; Indentation hardness ; Ultimate tensile strength Metallurgical and Alloy Processes ; Intermetallics and Advanced Alloy Properties ; Metallic Glasses and Amorphous Alloys
Authors: Enayi Onaji | Jawwad Yusuf | Hamza Abba | Maryam Abdullahi
Source:  (article, 2025-11-13)
Field: Chemistry — Organic Chemistry

Novel Chalcone Derivatives as Potent Lyn Tyrosine Kinase Inhibitors: A Promising In-Silico Approach for Targeted Therapy in Triple-Negative Breast Cancer Triple-negative breast cancer (TNBC) accounts for approximately 10–15% of breast cancer cases and poses a significant clinical challenge due to its aggressive nature and poorer survival outcomes compared to other subtypes. This is primarily attributed to the lack of estrogen, progesterone, and HER2 receptors, which render conventional hormone-based therapies ineffective. In this study, we employed in silico approaches to design and evaluate novel chalcone derivatives as potential inhibitors of Lyn tyrosine kinase, a critical enzyme implicated in TNBC progression. The designed compounds were screened for drug-likeness and toxicity, all meeting Lipinski’s rule of five and demonstrating favorable toxicity profiles. Molecular docking analyses identified five promising ligands, CHCN1, CHCN19, CHCN48, CHCN333, and CHCN94, that exhibited comparable binding affinities to key active site residues of Lyn kinase, including Asp385, Phe386, Gly387, Lys275, and Glu290. Among these, CHCN1 showed the highest binding affinity at –8.4 kcal/mol, likely due to interactions with Asp385 and Lys275. These results suggest that the chalcone derivatives may effectively disrupt Lyn-mediated signaling pathways essential for cancer cell survival, potentially inhibiting proliferation, metastasis, and invasion. Overall, this study provides valuable insights into the therapeutic potential of chalcone derivatives for TNBC, offering promising avenues for targeted intervention. LYN ; Chalcone ; Targeted therapy ; Breast cancer ; In silico ; Tyrosine kinase ; Cancer therapy ; Protein-Tyrosine Kinases ; Cancer Synthesis and biological activity ; Chronic Myeloid Leukemia Treatments ; Estrogen and related hormone effects
Authors: Deby Maghfira Prameswari | Woro Sumarni | Harjono Harjono
Source: IJPTE International Journal of Pedagogy and Teacher Education (article, 2025-11-02)
Field: Chemistry — Physical and Theoretical Chemistry

Ethnochemical Reconstruction of Dayak Tomun Tuak Fermentation for Contextual Chemistry Learning: an Applied Ethnography with AI-Augmented Qualitative Analysis &lt;p&gt;This study integrates AI-augmented qualitative analysis into an applied-ethnographic reconstruction of Dayak Tomun tuak fermentation to address the lack of curriculum-ready, place-based chemistry materials. Fieldwork in Arut Selatan, Central Kalimantan (August 2024–January 2025) engaged two participants (one brewer, one customary leader) through structured observation, semi-structured narrative interviews, and audiovisual documentation under inclusion criteria of ≥10 years’ practice and consistent use of traditional methods. Within Google Colab, ChatGPT assisted transcript segmentation and first-pass open–axial–selective coding; researchers verified all outputs line by line and iteratively refined a codebook with an audit trail. Findings clarify a two-stage process: glutinous-rice tapai for approximately 2–3 days followed by fermentation of a cooled sugar-and-spice infusion for approximately 4–5 days. Three controls consistently mattered: cooling to hand-warm (≤35 °C) before inoculation, tightly sealed vessels for defined durations, and spice infusion (clove, cinnamon, nutmeg, long pepper, black pepper) for flavor and perceived “cleanliness.” Sensory shift from sweet to bitter aligned with community assessments of progress; sociocultural boundaries (acid exclusion, restricted access, optional kapur sirih markings) co-occurred with empirical controls. We provide four curriculum-aligned exemplars for Grades 10–11: stoichiometry and reaction progress with simulated sucrose musts; anaerobiosis and gas balance via sealed-jar CO₂ capture; phenolic antioxidant assays (DPPH) using culinary spices with safety notes; and pH-shift demonstrations framed by the acid-exclusion hypothesis. Limitations include no instrumental ABV, pH, or microbiome data; pathway figures are interpretive. Future work should prioritize spot pH/Brix and hydrometer ABV, along with microbiome–metabolome mapping to strengthen the scientific and educational bridge.&lt;/p&gt; Documentation ; Narrative ; Thematic analysis ; Ethnography ; Facilitator ; Inclusion (mineral) ; Qualitative research ; Qualitative analysis ; Participant observation Various Chemistry Research Topics ; Science Education and Pedagogy ; Herbal Medicine and Trade Cooperation
Authors: Juntao Wang | Ruifeng Li | Xiaofei Fu | Shuai Huo | Lijiao Wang | Fengmin Shao | Yue Gu
Source: Frontiers in Pharmacology (article, 2025-12-18)
Field: Materials Science — Materials Chemistry

Nanozyme-armored natural enzymes for acute kidney injury management via inflammation regulation and oxidative damage mitigation This study successfully developed a CAT@MnS nanozyme that integrates ROS scavenging with inflammation regulation. The biomimetic mineralization strategy enhanced the stability and therapeutic synergy of the system. The nanozyme offers a new approach for the synergistic treatment of AKI and shows promising potential for translational application. Inflammation ; Oxidative stress ; Acute kidney injury ; Kidney ; Enzyme ; Reactive oxygen species Advanced Nanomaterials in Catalysis ; Nanoplatforms for cancer theranostics ; Nanocluster Synthesis and Applications
Authors: David Schwarz | Viacheslav Slesarenko
Source: Composites Part C Open Access (article, 2025-04-18)
Field: Materials Science — Polymers and Plastics

Correlating fluorescence and residual stiffness in self-reporting microcapsule composites with an intact soft matrix Self-reporting microcapsule-based systems are highly valuable for providing information about a composite’s health, whether by indicating the location of damage or, in more advanced cases, reflecting the extent of damage through intensity of fluorescence. However, measuring such intensity alone is insufficient for evaluating the deterioration of a composite’s mechanical properties. Using self-reporting stiff capsules containing tetraphenylethylene (TPE) and hexyl acetate embedded in a soft polymeric matrix, we observe that accurately assessing mechanical properties after damage in evaporation-based self-reporting systems requires not only measuring fluorescence brightness but also accounting for the time elapsed since the rupture of the capsules. While the fluorescence–stiffness correlation can be approximated by a linear fit at any given time, the proportionality coefficient gradually evolves, stabilizing only hours after capsule rupture. This study highlights the importance of considering the transient nature of fluorescence–stiffness relationships when leveraging self-reporting composites for advanced damage evaluation. • Microcapsules in a soft matrix indicate high applied strain prior to matrix damage. • Drop in Young’s modulus is propotional to fluorescence intensity at a given moment. • Proportionality coefficient is transient, hence is the self-reporting mechanism. Composite material ; Materials science ; Stiffness ; Residual ; Matrix (chemical analysis) ; Fluorescence ; Mathematics ; Algorithm ; Optics ; Physics Polymer composites and self-healing ; Polydiacetylene-based materials and applications ; Photochromic and Fluorescence Chemistry
Authors: Himanshu Yadav | Shivangni Rathore | Revathi A. Gupt
Source: International Journal of Newgen Research in Pharmacy & Healthcare (article, 2025-08-01)
Field: Materials Science — Biomaterials

Nanotechnology in Pharmacy: A Comprehensive Review of Emerging Trends and Applications Nanotechnology has revolutionized the pharmaceutical sciences by offering innovative strategies for drug formulation, delivery, and diagnostics. This review offers an in-depth examination of the new trends and uses of nanotechnology in the field of pharmacy. The aim is to emphasize how nanoscale materials and systems improve the bioavailability, targeting effectiveness, and therapeutic results of pharmaceutical compounds. The methodology involves a thorough evaluation of recent literature, concentrating on different nanocarrier systems, including liposomes, solid lipid nanoparticles, dendrimers, and polymeric nanoparticles and nanoemulsions. The review also examines their roles in overcoming challenges like poor solubility, limited permeability, and non-specific distribution of conventional drugs. Key applications explored include cancer therapy, brain-targeted drug delivery, transdermal systems, and vaccine development. Furthermore, advances in nanodiagnostics and personalized nanomedicine are discussed, along with regulatory and safety considerations. The findings underscore the transformative potential of nanotechnology to reshape pharmaceutical development and therapeutics. In conclusion, continued interdisciplinary research and responsible integration of nanotechnological innovations are critical for their safe and effective translation into clinical practice. Pharmacy ; Nanotechnology ; Data science ; Engineering ethics ; Medicine ; Engineering ; Computer science ; Materials science ; Family medicine Nanoparticle-Based Drug Delivery ; Graphene and Nanomaterials Applications ; Advanced Drug Delivery Systems