jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Jaehyun Kim | Jun Ho Lee | Jong‐Min Lee | Antonio Facchetti | Tobin J. Marks | Sung Kyu Park
Source: Small Methods (review, 2023-05-18)
Field: Materials Science — Materials Chemistry

Recent Advances in Low‐Dimensional Nanomaterials for Photodetectors New emerging low-dimensional such as 0D, 1D, and 2D nanomaterials have attracted tremendous research interests in various fields of state-of-the-art electronics, optoelectronics, and photonic applications due to their unique structural features and associated electronic, mechanical, and optical properties as well as high-throughput fabrication for large-area and low-cost production and integration. Particularly, photodetectors which transform light to electrical signals are one of the key components in modern optical communication and developed imaging technologies for whole application spectrum in the daily lives, including X-rays and ultraviolet biomedical imaging, visible light camera, and infrared night vision and spectroscopy. Today, diverse photodetector technologies are growing in terms of functionality and performance beyond the conventional silicon semiconductor, and low-dimensional nanomaterials have been demonstrated as promising potential platforms. In this review, the current states of progress on the development of these nanomaterials and their applications in the field of photodetectors are summarized. From the elemental combination for material design and lattice structure to the essential investigations of hybrid device architectures, various devices and recent developments including wearable photodetectors and neuromorphic applications are fully introduced. Finally, the future perspectives and challenges of the low-dimensional nanomaterials based photodetectors are also discussed. Photodetector ; Nanomaterials ; Neuromorphic engineering ; Photonics ; Materials science ; Electronics ; Nanotechnology ; Optoelectronics ; Computer science ; Engineering ; Electrical engineering ; Artificial intelligence ; Artificial neural network 2D Materials and Applications ; Perovskite Materials and Applications ; Quantum Dots Synthesis And Properties
Authors: Raquel Dantas | Catarina Ribeiro | Manuel Souto
Source: Chemical Communications (review, 2023-11-28)
Field: Materials Science — Materials Chemistry

Organic electrodes based on redox-active covalent organic frameworks for lithium batteries Electroactive organic materials have received much attention as alternative electrodes for metal-ion batteries due to their high theoretical capacity, resource availability, and environmental friendliness. In particular, redox-active covalent organic frameworks (COFs) have recently emerged as promising electrodes due to their tunable electrochemical properties, insolubility in electrolytes, and structural versatility. In this Highlight, we review some recent strategies to improve the energy density and power density of COF electrodes for lithium batteries from the perspective of molecular design and electrode optimisation. Some other aspects such as stability and scalability are also discussed. Finally, the main challenges to improve their performance and future prospects for COF-based organic batteries are highlighted. Electrode ; Redox ; Lithium (medication) ; Organic radical battery ; Materials science ; Covalent bond ; Energy density ; Nanotechnology ; Chemical engineering ; Energy storage ; Chemistry ; Electrochemistry ; Inorganic chemistry ; Power (physics) ; Engineering physics ; Organic chemistry ; Physics Covalent Organic Framework Applications ; Advanced battery technologies research ; Advanced Battery Materials and Technologies
Authors: Tianyi Ma | Kunlun Huang | Nan Cheng
Source: International Journal of Molecular Sciences (review, 2023-08-28)
Field: Materials Science — Materials Chemistry

Recent Advances in Nanozyme-Mediated Strategies for Pathogen Detection and Control Pathogen detection and control have long presented formidable challenges in the domains of medicine and public health. This review paper underscores the potential of nanozymes as emerging bio-mimetic enzymes that hold promise in effectively tackling these challenges. The key features and advantages of nanozymes are introduced, encompassing their comparable catalytic activity to natural enzymes, enhanced stability and reliability, cost effectiveness, and straightforward preparation methods. Subsequently, the paper delves into the detailed utilization of nanozymes for pathogen detection. This includes their application as biosensors, facilitating rapid and sensitive identification of diverse pathogens, including bacteria, viruses, and plasmodium. Furthermore, the paper explores strategies employing nanozymes for pathogen control, such as the regulation of reactive oxygen species (ROS), HOBr/Cl regulation, and clearance of extracellular DNA to impede pathogen growth and transmission. The review underscores the vast potential of nanozymes in pathogen detection and control through numerous specific examples and case studies. The authors highlight the efficiency, rapidity, and specificity of pathogen detection achieved with nanozymes, employing various strategies. They also demonstrate the feasibility of nanozymes in hindering pathogen growth and transmission. These innovative approaches employing nanozymes are projected to provide novel options for early disease diagnoses, treatment, and prevention. Through a comprehensive discourse on the characteristics and advantages of nanozymes, as well as diverse application approaches, this paper serves as a crucial reference and guide for further research and development in nanozyme technology. The expectation is that such advancements will significantly contribute to enhancing disease control measures and improving public health outcomes. Pathogen ; Biochemical engineering ; Computer science ; Identification (biology) ; Computational biology ; Nanotechnology ; Risk analysis (engineering) ; Biology ; Engineering ; Medicine ; Ecology ; Immunology Advanced Nanomaterials in Catalysis ; Advanced biosensing and bioanalysis techniques ; Biosensors and Analytical Detection
Authors: Xiaojie Sun | Mengxue Zhang | Jinfeng Liu | Guangyan Hui | Xiguang Chen | Chao Feng
Source: Advanced Science (review, 2023-12-03)
Field: Materials Science — Biomaterials

The Art of Exploring Diatom Biosilica Biomaterials: From Biofabrication Perspective Diatom is a common single-cell microalgae with large species and huge biomass. Diatom biosilica (DB), the shell of diatom, is a natural inorganic material with a micro-nanoporous structure. Its unique hierarchical porous structure gives it great application potential in drug delivery, hemostat materials, and biosensors, etc. However, the structural diversity of DB determines its different biological functions. Screening hundreds of thousands of diatom species for structural features of DB that meet application requirements is like looking for a needle in a seaway. And the chemical modification methods lack effective means to control the micro-nanoporous structure of DB. The formation of DB is a typical biomineralization process, and its structural characteristics are affected by external environmental conditions, genes, and other factors. This allows to manipulate the micro-nanostructure of DB through biological regulation method, thereby transforming the screening mode of the structure function of DB from a needle in a seaway to biofabrication mode. This review focuses on the formation, biological modification, functional activity of DB structure, and its application in biomaterials field, providing regulatory strategies and research idea of DB from the perspective of biofabrication. It will also maximize the possibility of using DB as biological materials. Biofabrication ; Nanotechnology ; Diatom ; Nanoporous ; Biomineralization ; Materials science ; Biochemical engineering ; Biology ; Tissue engineering ; Engineering ; Ecology ; Chemical engineering ; Biomedical engineering Diatoms and Algae Research ; Protist diversity and phylogeny ; Paleontology and Stratigraphy of Fossils
Authors: Fredrik Eriksson | Erik Fransson | Christopher Linderälv | Zheyong Fan | Paul Erhart
Source: ACS Nano (article, 2023-12-08)
Field: Materials Science — Materials Chemistry

Tuning the Through-Plane Lattice Thermal Conductivity in van der Waals Structures through Rotational (Dis)ordering It has recently been demonstrated that MoS<sub>2</sub> with irregular interlayer rotations can achieve an extreme anisotropy in the lattice thermal conductivity (LTC), which is, for example, of interest for applications in waste heat management in integrated circuits. Here, we show by atomic-scale simulations based on machine-learned potentials that this principle extends to other two-dimensional materials, including C and BN. In all three materials, introducing <i>rotational disorder</i> drives the through-plane LTC to the glass limit, while the in-plane LTC remains almost unchanged compared to those of the ideal bulk materials. We demonstrate that the ultralow through-plane LTC is connected to the collapse of their transverse acoustic modes in the through-plane direction. Furthermore, we find that the twist angle in periodic moiré structures representing <i>rotational order</i> provides an efficient means for tuning the through-plane LTC that operates for all chemistries considered here. The minimal through-plane LTC is obtained for angles between 1 and 4° depending on the material, with the biggest effect in MoS<sub>2</sub>. The angular dependence is correlated with the degree of stacking disorder in the materials, which in turn is connected to the slip surface. This provides a simple descriptor for predicting the optimal conditions at which the LTC is expected to become minimal. Anisotropy ; van der Waals force ; Transverse plane ; Materials science ; Thermal conductivity ; Slip (aerodynamics) ; Lattice (music) ; Stacking ; Condensed matter physics ; Plane (geometry) ; Lattice plane ; Physics ; Geometry ; Optics ; Composite material ; Molecule ; Nuclear magnetic resonance ; Quantum mechanics ; Diffraction Thermal properties of materials ; Advanced Thermoelectric Materials and Devices ; Graphene research and applications
Authors: Maria Khalikova | Jakub Jireš | Ondřej Horáček | Michal Douša | Radim Kučera | Lucie Nováková
Source: Mass Spectrometry Reviews (review, 2023-07-28)
Field: Chemistry — Spectroscopy

What is the role of current mass spectrometry in pharmaceutical analysis? The role of mass spectrometry (MS) has become more important in most application domains in recent years. Pharmaceutical analysis is specific due to its stringent regulation procedures, the need for good laboratory/manufacturing practices, and a large number of routine quality control analyses to be carried out. The role of MS is, therefore, very different throughout the whole drug development cycle. While it dominates within the drug discovery and development phase, in routine quality control, the role of MS is minor and indispensable only for selected applications. Moreover, its role is very different in the case of analysis of small molecule pharmaceuticals and biopharmaceuticals. Our review explains the role of current MS in the analysis of both small-molecule chemical drugs and biopharmaceuticals. Important features of MS-based technologies being implemented, method requirements, and related challenges are discussed. The differences in analytical procedures for small molecule pharmaceuticals and biopharmaceuticals are pointed out. While a single method or a small set of methods is usually sufficient for quality control in the case of small molecule pharmaceuticals and MS is often not indispensable, a large panel of methods including extensive use of MS must be used for quality control of biopharmaceuticals. Finally, expected development and future trends are outlined. Biochemical engineering ; Chemistry ; Quality (philosophy) ; Drug discovery ; Drug development ; Quality by Design ; Risk analysis (engineering) ; Nanotechnology ; Drug ; Pharmacology ; Business ; Engineering Mass Spectrometry Techniques and Applications ; Analytical Chemistry and Chromatography ; Pesticide Residue Analysis and Safety
Authors: Mohammad Habibur Rahman Molla | Mohammed Othman Aljahdali | Md Afsar Ahmed Sumon | Amer H. Asseri | Hisham N. Altayb | Md. Shafiqul Islam | Ahad Amer Alsaiari | F A Dain Md Opo | Nushrat Jahan | Foysal Ahammad | Farhan Mohammad
Source: Pharmaceuticals (article, 2023-01-13)
Field: Materials Science — Biomaterials

Integrative Ligand-Based Pharmacophore Modeling, Virtual Screening, and Molecular Docking Simulation Approaches Identified Potential Lead Compounds against Pancreatic Cancer by Targeting FAK1 Pancreatic cancer is a very deadly disease with a 5-year survival rate, making it one of the leading causes of cancer-related deaths globally. Focal adhesion kinase 1 (FAK1) is a ubiquitously expressed protein in pancreatic cancer. FAK, a tyrosine kinase that is overexpressed in cancer cells, is crucial for the development of tumors into malignant phenotypes. FAK functions in response to extracellular signals by triggering transmembrane receptor signaling, which enhances focal adhesion turnover, cell adhesion, cell migration, and gene expression. The ligand-based drug design approach was used to identify potential compounds against the target protein, which included molecular docking: ADME (absorption, distribution, metabolism, and excretion), toxicity, molecular dynamics (MD) simulation, and molecular mechanics generalized born surface area (MM-GBSA). Following the retrieval of twenty hits, four compounds were selected for further evaluation based on a molecular docking approach. Three newly discovered compounds, including PubChem CID24601203, CID1893370, and CID16355541, with binding scores of -10.4, -10.1, and -9.7 kcal/mol, respectively, may serve as lead compounds for the treatment of pancreatic cancer associated with FAK1. The ADME (absorption, distribution, metabolism, and excretion) and toxicity analyses demonstrated that the compounds were effective and nontoxic. However, further wet laboratory investigations are required to evaluate the activity of the drugs against the cancer. ADME ; Pharmacophore ; Pancreatic cancer ; Docking (animal) ; Chemistry ; Virtual screening ; Cancer research ; Pharmacology ; Cancer ; Biology ; Biochemistry ; Computational biology ; Medicine ; Drug ; Internal medicine Nanoparticle-Based Drug Delivery ; Advanced Breast Cancer Therapies ; Computational Drug Discovery Methods
Authors: Ben Zhong Tang | Ping Shen | Yu Xiong | Tianjing Wu | Gang Wang | Yucheng Wang | Liping Zhang | Han Yang | Wei He | Jian Du | Xuedong Wei | Siwei Zhang | Zijie Qiu | Weijie Zhang | Zheng Zhao
Source: National Science Review (article, 2023-11-07)
Field: Materials Science — Materials Chemistry

Bright, photostable and long-circulating NIR-II nanoparticles for whole-process monitoring and evaluation of renal transplantation Kidney transplantation is the gold standard for the treatment of end-stage renal diseases (ESRDs). However, the scarcity of donor kidneys has caused more and more ESRD patients to be stuck on the waiting list for transplant surgery. Improving the survival rate for renal grafts is an alternative solution to the shortage of donor kidneys. Therefore, real-time monitoring of the surgical process is crucial to the success of kidney transplantation, but efficient methods and techniques are lacking. Herein, a fluorescence technology based on bright, photostable and long-circulating aggregation-induced emission (AIE) active NIR-II nano-contrast agent DIPT-ICF nanoparticles for the whole-process monitoring and evaluation of renal transplantation has been reported. In the aggregated state, DIPT-ICF exhibits superior photophysical properties compared with the commercial dyes IR-26 and IR-1061. Besides, the long-circulating characteristic of the AIE nano-contrast agent helps to achieve renal angiography in kidney retrieval surgery, donor kidney quality evaluation, diagnosing vascular and ureteral complications, and assessment of renal graft reperfusion beyond renovascular reconstruction, which considerably outperforms the clinically approved indocyanine green (ICG). Transplantation ; Economic shortage ; Medicine ; Kidney ; Kidney transplantation ; Surgery ; Urology ; Internal medicine Nanocluster Synthesis and Applications ; Neurological Complications and Syndromes ; Perovskite Materials and Applications
Authors: Chaohua Zhang | Qiangwen Lai | Wu Wang | Xuyang Zhou | Kailiang Lan | Lipeng Hu | Bowen Cai | Matthias Wuttig | Jiaqing He | Fusheng Liu | Yuan Yu
Source: Advanced Science (article, 2023-06-29)
Field: Materials Science — Materials Chemistry

Gibbs Adsorption and Zener Pinning Enable Mechanically Robust High‐Performance Bi<sub>2</sub>Te<sub>3</sub>‐Based Thermoelectric Devices Bi<sub>2</sub> Te<sub>3</sub> -based alloys have great market demand in miniaturized thermoelectric (TE) devices for solid-state refrigeration and power generation. However, their poor mechanical properties increase the fabrication cost and decrease the service durability. Here, this work reports on strengthened mechanical robustness in Bi<sub>2</sub> Te<sub>3</sub> -based alloys due to thermodynamic Gibbs adsorption and kinetic Zener pinning at grain boundaries enabled by MgB<sub>2</sub> decomposition. These effects result in much-refined grain size and twofold enhancement of the compressive strength and Vickers hardness in (Bi<sub>0.5</sub> Sb<sub>1.5</sub> Te<sub>3</sub> )<sub>0.97</sub> (MgB<sub>2</sub> )<sub>0.03</sub> compared with that of traditional powder-metallurgy-derived Bi<sub>0.5</sub> Sb<sub>1.5</sub> Te<sub>3</sub> . High mechanical properties enable excellent cutting machinability in the MgB<sub>2</sub> -added samples, showing no missing corners or cracks. Moreover, adding MgB<sub>2</sub> facilitates the simultaneous optimization of electron and phonon transport for enhancing the TE figure of merit (ZT). By further optimizing the Bi/Sb ratio, the sample (Bi<sub>0.4</sub> Sb<sub>1.6</sub> Te<sub>3</sub> )<sub>0.97</sub> (MgB<sub>2</sub> )<sub>0.03</sub> shows a maximum ZT of ≈1.3 at 350 K and an average ZT of 1.1 within 300-473 K. As a consequence, robust TE devices with an energy conversion efficiency of 4.2% at a temperature difference of 215 K are fabricated. This work paves a new way for enhancing the machinability and durability of TE materials, which is especially promising for miniature devices. Materials science ; Machinability ; Thermoelectric effect ; Vickers hardness test ; Figure of merit ; Grain boundary ; Metallurgy ; Optoelectronics ; Thermodynamics ; Microstructure ; Machining Advanced Thermoelectric Materials and Devices ; Thermal properties of materials ; Physics of Superconductivity and Magnetism
Authors: Nur Çebi | Hatice Beki̇roğlu | Azime Erarslan | Luis Rodriguez‐Saona
Source: Molecules (review, 2023-04-26)
Field: Chemistry — Analytical Chemistry

Rapid Sensing: Hand-Held and Portable FTIR Applications for On-Site Food Quality Control from Farm to Fork Today, one of the world’s biggest problems is the assurance of food integrity from farm to fork. Economically motivated food adulteration and food authenticity problems are increasing daily with considerable health and economic effects. Early detection and prevention of food integrity-related problems could be provided by the application of effective on-site food analysis technologies. FTIR spectroscopy coupled with chemometrics can be used for the rapid quality control of a wide variety of food products with fast, high-throughput, accurate and nondestructive analysis advantages. In particular, hand-held and portable FTIR instruments have the potential to surveil food quality and food safety in various critical segments of the food supply chain. In this review, we explore the abilities of hand-held and portable FTIR spectrometers combined with multivariate statistics to conduct a quality evaluation of various food products in terms of food adulteration and authenticity issues. An examination of the literature showed that comparable results were obtained based on detection limits, correlation coefficient (R2) values, standard error values and discrimination power by using both portable/hand-held FTIR spectrometers and benchtop FTIR spectrometers. In conclusion, this review highlights the potential usefulness of portable and hand-held FTIR spectrometers combined with chemometrics for maintaining the food quality through the presentation of various applications that may shed light for on-site food control at any point of the food supply chain. Chemometrics ; Food quality ; Fourier transform infrared spectroscopy ; Quality assurance ; Quality (philosophy) ; Food processing ; Food chain ; Spectrometer ; Food industry ; Food products ; Supply chain ; Computer science ; Biochemical engineering ; Process engineering ; Agricultural engineering ; Food science ; Environmental science ; Engineering ; Chemistry ; Business ; Operations management ; Marketing Spectroscopy and Chemometric Analyses ; Identification and Quantification in Food ; Advanced Chemical Sensor Technologies
Authors: Samuel Pinilla | Johannes E. Fröch | Seyyed Reza Miri Rostami | Vladimir Katkovnik | Igor Shevkunov | Arka Majumdar | Karen Egiazarian
Source: Science Advances (article, 2023-05-26)
Field: Materials Science — Surfaces, Coatings and Films

Miniature color camera via flat hybrid meta-optics The race for miniature color cameras using flat meta-optics has rapidly developed the end-to-end design framework using neural networks. Although a large body of work has shown the potential of this methodology, the reported performance is still limited due to fundamental limitations coming from meta-optics, mismatch between simulated and resultant experimental point spread functions, and calibration errors. Here, we use a HIL optics design methodology to solve these limitations and demonstrate a miniature color camera via flat hybrid meta-optics (refractive + meta-mask). The resulting camera achieves high-quality full-color imaging for a 5-mm aperture optics with a focal length of 5 mm. We observed a superior quality of the images captured by the hybrid meta-optical camera compared to a compound multi-lens optics of a mirrorless commercial camera. Optics ; Geometrical optics ; Lens (geology) ; Computer science ; Adaptive optics ; Focal length ; Image quality ; Calibration ; Aperture (computer memory) ; Artificial intelligence ; Physics ; Computer vision ; Image (mathematics) Optical Coatings and Gratings ; Photonic and Optical Devices ; Advanced Optical Imaging Technologies