jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: MOHAMMAD TITAN DARMAWAN | MUHAMAD HAFIZ ALVIANSYAH | ROZAQ DWI ADITYA | Nisrina Hasna Fadhila | NURSILA JULIHAYAT SAFIKA | Oricya Salma | Rachmannia Nugraheni | Rafika Kusuma Hidayati | SUNNIA NADHIRA | AHMAD DWI SETYAWAN
Source: Cell Biology and Development (article, 2026-02-17)
Field: Materials Science — Biomaterials

Review: Regulated polyhydroxyalkanoate granule biology and polymer phenotype in mangrove-associated bacteria Abstract. Darmawan MT, ⁠Alviansyah MH, Aditya RD, Fadhila NH, Safika NJ, Salma O, Nugraheni R, Hidayati RK, Nadhira S, Setyawan AD. 2025. Review: Regulated polyhydroxyalkanoate granule biology and polymer phenotype in mangrove-associated bacteria. Cell Biol Dev 9: 129-157. Polyhydroxyalkanoates (PHAs) are biodegradable biopolymers whose molecular weight, composition, and dispersity strongly determine material performance and industrial applicability. Despite extensive efforts to optimize culture conditions and genetic constructs, reproducible control of PHA polymer phenotype remains challenging. This review reinterprets PHA accumulation from a cell-biological perspective by positioning PHA granules as regulated intracellular organelles rather than passive repositories of excess carbon. Synthesizing evidence from mechanistic studies, culture-based experiments, and gene-centric analyses, the review demonstrates that polymer phenotype-including molecular-weight distribution, structural heterogeneity, and batch-to-batch reproducibility-emerges as a physiological output shaped by regulatory gating and granule state. PHA accumulation is shown to be an active and reversible storage strategy embedded within global stress-response networks, rather than a simple consequence of metabolic overflow. Granule-associated proteins, spatial organization, and turnover dynamics act as critical intermediaries translating regulatory state into material properties. The review further highlights that widespread reliance on production-oriented metrics, such as polymer yield or percentage of cell dry weight, obscures intracellular processes that govern polymer history and quality, contributing to inconsistencies across studies. Mangrove-associated bacteria are used as a biologically informative stress-context model to illustrate how conserved intracellular storage mechanisms operate under recurring physiological constraints, without invoking environmental determinism. Building on these insights, a regulatory-granule-phenotype framework is proposed that reframes reproducibility as a biological property dependent on granule-state stability rather than a purely technical issue. By foregrounding granule-level control, this synthesis provides a coherent foundation for integrating cellular regulation with polymer phenotype and outlines experimental directions for achieving more predictable and interpretable PHA production. Polyhydroxyalkanoates ; Intracellular ; Synthetic biology ; Bacteria ; Phenotype ; Polymer ; Organism biodegradable polymer synthesis and properties ; Microplastics and Plastic Pollution ; Polymer-Based Agricultural Enhancements
Authors: Maria Apostolopoulou | Nikos Kavousanos | Feidias Bairamis | Konstantinos Brintakis | Αθανασία Κωστοπούλου | Emmanuel Stratakis | Emmanuel Spanakis | R. Ramı́rez | Dimitrios Kalderis | Dimitra Vernardou
Source: C – Journal of Carbon Research (article, 2026-03-03)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Exploring Activation-Free Biochars Through a Comprehensive Characterization Conventional carbon-based electrodes like graphene are limited by costly, energy-intensive synthesis that rely on non-renewable precursors, challenging their scalability. While biomass-derived carbons (biochar) are a promising green alternative, achieving state-of-the-art performance typically requires chemical activation. Developing high-performance biochar through simple, scalable, and green pathways therefore remains a key challenge. In this work, we present a comprehensive physicochemical characterization of activation-free biochar derived from walnut, carob, rice husk and coffee via simple pyrolysis. Surface area, porosity and structural disorder were systematically analyzed to identify the key parameters governing ion interaction and charge storage. The results reveal a strong dependence of biochar properties on biomass type, with pronounced differences in accessible porosity and defect density. Among the materials studied, walnut-derived biochar combined a high specific surface area (1146 m2/g) with a high degree of structural disorder, highlighting the critical role of defects in enhancing ion adsorption and charge-transfer processes. Electrochemical measurements illustrated the functional implications of these intrinsic characteristics. Overall, this work demonstrates that carefully selected, unprocessed biomass can serve as a direct, low-cost source of functional carbon electrodes, providing insight into the parameters that dictate their electrochemical behavior and enable broader functional potential. Biochar ; Characterization (materials science) ; Carbon fibers ; Biomass (ecology) ; Porosity ; Electrochemistry ; Adsorption Supercapacitor Materials and Fabrication ; Adsorption and biosorption for pollutant removal ; Advancements in Battery Materials
Authors: Fabian Stoelzel | Thorsten Gerdes
Source: International Journal of Applied Glass Science (article, 2026-01-27)
Field: Materials Science — Ceramics and Composites

Strengthening Potentials of Lithium‐Doped Soda–Lime–Silicate Glasses Through Surface Crystallization of Quartz‐ss ABSTRACT The formation of a crystallized surface layer, having a lower coefficient of thermal expansion (CTE) than the parent glass, can be exploited to place the glass surface under compression during cooling from crystallization temperature and hence improve mechanical properties. In our study, we focused on the understanding of the compositional dependency of the surface crystallization of quartz solid solutions (Qz‐ss) with potentially low CTE. Specifically, we investigated the crystallization of melt‐prepared soda–lime–silicate glasses with variable Al 2 O 3 content that were doped with lithium in exchange for sodium. Further, the role of ZnO and MgO in the crystallization was evaluated. Despite rather complex glass compositions, the observed cell parameters of the obtained Qz‐ss are close to the corresponding ternary Li 2 O─Al 2 O 3 ─SiO 2 (LAS) system. Further, a simple model was applied to predict the in‐plane stresses in the surface. For modeled compositions down to 5.5 mol% Al 2 O 3 , formation of a compressive layer for the complete range of the crystalline content can be observed. Our findings illustrate the potential of strengthening glasses through surface crystallization as an alternative to thermal‐ and chemical strengthening to make glass‐packaging more weight competitive. The results can help to optimize glass compositions that can be strengthened by this method. Crystallization ; Thermal expansion ; Ternary operation ; Layer (electronics) ; Quartz ; Surface layer ; Surface (topology) ; Thermal Glass properties and applications ; Structural Analysis of Composite Materials ; Microwave Dielectric Ceramics Synthesis
Authors: Mukundam Vanga | Sara Jahanghiri | Justin Davis | Rajendra Prasad Nandi | Ashutosh Sahoo | Pavel Kucheryavy | Roger A. Lalancette | Edward M. Bonder | Zhifeng Ding | Frieder Jäkle
Source: Journal of the American Chemical Society (article, 2026-03-09)
Field: Chemistry — Organic Chemistry

Regioselective Synthesis of Ambipolar B–N Lewis Pair Functionalized Pyrenes: Structural Dynamics, Emission Tuning, and Applications in Live Cell Imaging and as Electrochemiluminescent Materials Intramolecular B←N Lewis pair functionalization of polycyclic aromatic hydrocarbons (PAHs) is emerging as a powerful strategy for tailoring their optical and electronic properties to specific applications. Herein, we report the design and synthesis of four quadrupolar pyrene fluorophores containing triarylamine donor and pyridyl-borane acceptor substituents by N-directed electrophilic C-H borylation in the K-region. Introduction of rigid six-membered B-N heterocycles greatly decreased the lowest unoccupied molecular orbital (LUMO) energy levels and red-shifted the absorption and emission maxima compared to the nonborylated precursors. These pyrenes exhibit absorptions spanning the entire visible region and intense green to deep red and near-infrared fluorescence, with impressive quantum yields as high as 82%. The simultaneous presence of pyridyl-borane acceptor and arylamine donor units also enables facile reversible multiredox oxidation and reduction processes. The advantageous photophysical and electrochemical characteristics are highly attractive for optoelectronic devices and (bio)imaging applications. The pyrene derivative with the most red-shifted emission, <b>5-Pf</b>, was further evaluated in live cell imaging studies, showing effective staining of acidic compartments, including lysosomes. In addition, we demonstrate the outstanding performance of <b>5-Pf</b> as a novel electrochemiluminescent (ECL) luminophore through annihilation and coreactant experiments in cyclic voltammetry and pulsing modes. Spooling ECL spectroscopy revealed a strong emission with a maximum at 646 nm, in good agreement with the photoinduced emission maximum at 660 nm. A superior absolute ECL efficiency (Φ<sub>ECL</sub>) of up to 0.9 ± 0.1%, exceeding that of typically employed [Ru(bpy)<sub>3</sub>]<sup>2+</sup>, was achieved during CV scanning with benzoyl peroxide as a coreactant. Luminophore ; Bathochromic shift ; Acceptor ; Quantum yield ; Pyrene ; Cyclic voltammetry ; Chromophore ; Intramolecular force ; BODIPY ; Corrole Organoboron and organosilicon chemistry ; Luminescence and Fluorescent Materials ; Synthesis and Properties of Aromatic Compounds
Authors: D. Dl Trapani | F. Saiano | Simona Boninelli | Sajeel Khan | I. Crupi | Roberto Macaluso | Mauro Mosca
Source: Materials (article, 2026-02-11)
Field: Materials Science — Materials Chemistry

From Photoluminescence Optimization to Green LED Fabrication: The Role of Molar Precursor Ratio in Carbon Dots Carbon dots have emerged as promising luminescent materials for solid-state lighting and color-conversion applications; however, their photoluminescence efficiency in the solid state is often limited by aggregation-induced quenching phenomena. In this work, we systematically investigate the role of the molar precursor ratio on the optical properties of green-emitting carbon dots, with the aim of establishing a direct link between synthesis parameters, photoluminescence optimization, and device-level performance. By carefully tuning the precursor ratio during synthesis, a significant enhancement of photoluminescence intensity and a strong suppression of solid-state quenching are achieved while preserving spectral stability in the green region. The optimized carbon dots exhibit improved radiative recombination and favorable optical characteristics for solid-state integration. Building on these results, the carbon dots are successfully employed as color-conversion layers in the fabrication of green light-emitting diodes, demonstrating efficient green emission under electrical excitation. This study highlights precursor ratio engineering as a simple and effective strategy to tailor carbon dot photoluminescence and provides a clear pathway from materials optimization to the realization of green color-conversion LED devices. Photoluminescence ; Carbon fibers ; Molar ratio ; Luminescence ; Quenching (fluorescence) ; Fabrication Carbon and Quantum Dots Applications ; Advanced Photocatalysis Techniques ; Silicon Nanostructures and Photoluminescence
Authors: RAKSHA | ASHUTOSH GUPTA | Moumita Saha | Sudheer Moorkoth | Abhay Bhardwaj | Aditya Dev Rajora
Source: International Journal of Applied Pharmaceutics (article, 2026-01-07)
Field: Materials Science — Materials Chemistry

DESIGN OF EXPERT-BASED ECO-FRIENDLY RP-HPLC ANALYTICAL METHOD FOR THE ESTIMATION OF LUMEFANTRINE FROM THE CARBON DOTS Objective: The most common and lethal malaria-causing species in humans, Plasmodium falciparum and Plasmodium vivax, are caused by protozoan parasites belonging to the genus Plasmodium. Due to the substantial therapeutic obstacles posed by these parasites, novel therapy strategies are being investigated. By improving the solubility and cellular absorption of antimalarial drugs, including lumefantrine (LUM), carbon dots (CDs), a new nanomaterial, hold promise for the management of malaria. In order to evaluate the stability, drug release profile, and percentage entrapment efficiency (%EE) of LUM-loaded CDs and support their potential for the treatment of malaria, this study set out to design and validate an analytical approach based on HPLC. Methods: A Design of Experiments (DoE) strategy was employed to optimize the HPLC process, systematically altering the injection volume, flow rate, buffer ratio, and buffer pH to improve performance. The following responses were tracked: theoretical plates (Tp), tailing factor (Tf), drug peak area, and retention time (RT). Following the requirements of ICH Q2(R2), linearity was established for LUM throughout a range of 0.5 to 20 µg/ml. Results: The result was a linear regression equation with an R2&gt;0.999, demonstrating strong linearity. For both intra-day and inter-day studies, the method's precision with a %CV&lt;2% and accuracy between 98 and 102% ensured repeatability when used for evaluating LUM stability, %EE, and drug release in CDs. The technique exhibited sensitivity for low concentrations and selectivity, separating LUM from excipients and degradation products. Its eco-friendliness was confirmed with an AGREE score of 0.7, indicating less waste and solvent consumption. Conclusion: The quantification of LUM in CDs, formulation parameter optimization, and the development of sustainable malaria treatment techniques are all made possible by this verified HPLC approach. Lumefantrine ; Repeatability ; Linearity ; Solvent ; Solubility ; Absorption (acoustics) ; Plasmodium falciparum ; Degradation (telecommunications) ; Drug Carbon and Quantum Dots Applications ; Electrochemical sensors and biosensors ; Silymarin and Mushroom Poisoning
Authors: Ingrid Sofía Rincón von Pastor | María Elena Sánchez Vergara | Luis Alberto Cantera Cantera
Source: PÄDI Boletín Científico de Ciencias Básicas e Ingenierías del ICBI (article, 2026-03-20)
Field: Materials Science — Materials Chemistry

Metal phthalocyanines as organic semiconductor layer in optoelectronic devices Devices were fabricated using donor metal phthalocyanines (MPc; M = Co, Cu) and the electron acceptor tetracyano-π-quinodimethane (TCNQ) as components of the active layer in a bulk heterojunction (BHJ) architecture. Initially, the optical behavior of the MPc+TCNQ layers was studied, followed by the fabrication of the devices employing indium tin oxide (ITO: In₂O₃(SnO₂)x) as the anode and silver (Ag) as the cathode. To optimize device performance, additional layers were introduced in a planar heterojunction (PHJ) configuration, using pentacene and bathocuproine as hole and electron transport layers, respectively. The study of its electrical behavior revealed that both light irradiation at different wavelengths and variations in electrode polarity affect charge transport, which is correlated with the type of phthalocyanine employed. In the case of the device containing CoPc, ohmic behavior was observed, whereas the device with CuPc exhibited ohmic behavior at low voltages, transitioning to space-charge-limited current (SCLC) conduction at higher voltages. Ohmic contact ; Heterojunction ; Indium tin oxide ; Phthalocyanine ; Indium ; Layer (electronics) ; Electrode ; Organic semiconductor Porphyrin and Phthalocyanine Chemistry ; Organic Electronics and Photovoltaics ; Magnetism in coordination complexes
Authors: Yu Fu | Yifeng Yao | Subhradip Paul | Kenji Mochizuki | Gaël De Paëpe
Source: Nature Communications (article, 2026-03-11)
Field: Chemistry — Spectroscopy

Water-generated dangling linkers in a metal-organic framework Metal-Organic Frameworks (MOFs) have attracted widespread attention for their applications in water-related contexts. A comprehensive understanding of the molecular-level interactions between water and MOFs is crucial for guiding molecular design and optimizing water-related applications. Water can act as a passive guest, interacting weakly with open metal sites or polar linkers without altering the framework, or as a reactive species that cleaves the dative bonds between inorganic clusters and organic linkers, leading to irreversible degradation. In this work, we uncover a significant impact of water on the metal-linker linkage in UiO-66, a prototype MOFs which is considered highly stable with water. The adsorption of water molecules in UiO-66 results in the displacement of firmly attached carboxylate groups of the linker, thereby transforming them into dangling carboxylate groups. These dangling groups are stabilized by water molecules and μ<sub>3</sub>-OH through hydrogen bonding. Remarkably, this structural transformation is reversible upon water removal. These findings were elucidated through the integration of multidimensional solid-state NMR, cutting-edge dynamic nuclear polarization (DNP) techniques, and computational calculations. By challenging conventional wisdom, our research has introduced a reversible molecular structure evolution scenario, redefining the understanding of water-MOF interactions. Dangling bond ; Carboxylate ; Molecule ; Hydrogen bond ; Adsorption ; Polarization (electrochemistry) ; Hydrogen ; Molecular dynamics Advanced NMR Techniques and Applications ; Metal-Organic Frameworks: Synthesis and Applications ; Magnetism in coordination complexes
Authors: Xintong Zhai | Mengjiao Wang | Wenfei Li | Xinyi Yin | Huiran Qi | Yuejiu Pang | Shupeng Su
Source: ACS Omega (article, 2026-02-16)
Field: Materials Science — Materials Chemistry

Formation and Stability of Pickering Emulsion Stabilized by Self-Aggregated Chitosan Particles near the pK <sub>a</sub> Stabilizing Pickering emulsions with highly hydrophilic biopolymers such as chitosan remains challenging due to their strong hydrophilicity. By adjusting the pH to impart minimal or zero charge, these highly hydrophilic particles can form stable Pickering emulsions. However, no consensus has been reached regarding the optimal pH to fabricate stable Pickering emulsions. Hence, this study focused on the narrow pH window near the p<i>K</i> <sub>a</sub> of chitosan (pH 6.1-6.9) to clarify the optimal pH and the related formation and stability mechanisms. At p<i>K</i> <sub>a</sub> (pH 6.5), chitosan formed self-aggregated particles with optimal amphiphilicity and moderate surface charge, facilitating robust adsorption at the oil-water interface. The resulting emulsions exhibit remarkably small droplet sizes, good fluidities, high encapsulation capacities, and exceptional stability against creaming, coalescence, flocculation, and centrifugation. In contrast, emulsions prepared at pH below 6.5 suffered from excessive hydrophilicity and poor coalescence stability, while those at pH above 6.5 experienced particle overaggregation and gelation, leading to compromised fluidity and interfacial integrity. This superior performance of Pickering emulsions at the optimal pH was attributed to the optimal hydrophilic-hydrophobic balance and moderate surface charge of the chitosan particles, facilitating smaller droplet formation and uniform particle coverage. This finding is pivotal for future applications of chitosan Pickering emulsions and offers insights for developing food-grade Pickering emulsions with other hydrophilic charged particles. Pickering emulsion ; Chitosan ; Adsorption ; Coalescence (physics) ; Emulsion ; Contact angle Pickering emulsions and particle stabilization ; Proteins in Food Systems ; Hydrogels: synthesis, properties, applications
Authors: Peng Cui | Fei Yin | Zhiwen Wang
Source: Scientific Reports (article, 2026-03-12)
Field: Materials Science — Materials Chemistry

Internal conversion dominates the excited state dynamics and fluorescence efficiency of mono-substituted TPE-BODIPY dyes In this study, we employ Density Functional Theory (DFT) and Time-Dependent DFT (TDDFT) to systematically investigate the excited-state dynamics of a series of six mono-tetraphenylethylene (TPE)–substituted BODIPY dyes (BDP-TPE-1 to -6). By modulating the TPE moiety with electron-donating (methoxy) and -accepting (dicyanovinyl) groups, we unravel the structural factors controlling the competition between radiative and nonradiative decay. Our calculations, validated against experimental quantum yields for structurally analogous derivatives (mean absolute error < 0.5%), reveal that the nonradiative decay channel via torsional motion to a conical intersection is kinetically suppressed across the series due to high activation barriers (ΔE‡ = 18.1–81.4 kcal/mol). Consequently, the fluorescence quantum yield (Φf) is almost exclusively governed by the competition between radiative decay (kr) and internal conversion (IC) from the S1 minimum. BDP-TPE-2, featuring a single dicyanovinyl acceptor, exhibits the highest predicted quantum yield (Φf ≈ 22%), not due to a superior radiative rate, but because of a uniquely suppressed IC rate (2.67 × 108 s−1) arising from exceptionally weak electronic coupling (V = 0.0038 eV) and minimal low-frequency reorganization energy (λl). Conversely, the poorest emitters, BDP-TPE-5 and BDP-TPE-6, are shown to suffer from exceptionally fast IC ( > 1010 s−1) driven by large electronic coupling and, crucially, large low-frequency reorganization energies. These results demonstrate that enhancing fluorescence efficiency in this scaffold depends critically on the strategic suppression of internal conversion by minimizing both electronic and vibrational coupling between the ground and excited states. The predicted quantum yields (Φf = 0.16-22%) represent intrinsic molecular properties validated against weak-AIE experimental benchmarks, and may be enhanced in solid-state applications if strong aggregation-induced emission occurs. Excited state ; Internal conversion ; Fluorescence ; Dynamics (music) ; Energy conversion efficiency ; State (computer science) Luminescence and Fluorescent Materials ; Photochemistry and Electron Transfer Studies ; Advanced Fluorescence Microscopy Techniques