jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Prin Chaksmithanont | Ketsana Bangsitthideth | Kwanputtha Arunprasert | Prasopchai Patrojanasophon | Chaiyakarn Pornpitchanarong
Source: Polymers (article, 2024-09-20)
Field: Materials Science — Biomaterials

Statistical-Based Optimization of Modified Mangifera indica Fruit Starch as Substituent for Pharmaceutical Tableting Excipient This study aimed to optimize modified starch from <i>Mangifera indica</i> (mango) fruit using acid hydrolysis and pre-gelatinization via computer-assisted techniques as a substituent for pharmaceutical tableting excipients. The hydrolysis and microwave-assisted pre-gelatinization time and temperature were optimized using a three-level factorial design. The modified starches were characterized for flowability, compressibility, and swelling properties. It was found that all parameters fit a quadratic model, which can be used to predict the properties of the modified starch. The optimized hydrolysis reaction was 3.8 h at 56.4 °C, while the pre-gelatinization reaction was 3 min at 150 °C. Structural changes were found, ascertaining that starch modification was successful. The optimized hydrolyzed starch showed superior properties in relative to unmodified M. indica fruit starch and comparable characteristics to conventional excipients. The optimized pre-gelatinized starch presented an excellent enhancement in the flow and compression properties, with %swelling greatly augmented 3.95-fold and 1.24-fold compared to unmodified starch and SSG, respectively. Additionally, the pre-gelatinized starch presented comparable binding effect, while the hydrolyzed powder had reduced binding capacity due to shorter chains. The findings revealed that the use of software-assisted design of experiment facilitated a data-driven approach to optimize the modifications. The optimized modified mango starch demonstrated potential as a multifunctional excipient, capable of functioning as binder, disintegrant, and diluent. Tableting ; Starch ; Factorial experiment ; Hydrolysis ; Swelling ; Materials science ; Excipient ; Mangifera ; Diluent ; Modified starch ; Chemical engineering ; Chemistry ; Organic chemistry ; Chromatography ; Composite material ; Mathematics biodegradable polymer synthesis and properties ; Food composition and properties ; Polysaccharides Composition and Applications
Authors: Teh Coey
Source: Progress in Drug Discovery & Biomedical Science (review, 2024-05-04)
Field: Materials Science — Biomaterials

Nanomedicine in Oncology: A Critical Review on Epidemiology, Health Impacts, Challenges, and Future Outlook Cancer remains a leading public health issue globally due to its increasing morbidity rate, with cancer cases predicted to double over the next 20 years. While current conventional treatments are the primary go-to in treating cancers, they still present ineffective due to adverse side effects, poor targeting, and drug resistance. In recent years, nanomedicines have emerged as a better alternative for cancer treatment in maximizing drug delivery, bioavailability, and therapeutic efficacy through passive and active mechanisms. Despite having high potential, the poor clinical translations and recent fund retractions have led to limited progress in cancer nanomedicine. Thus, this review aims to review and identify the role of nanomedicine in oncology by analyzing the involved epidemiological populations, potential health impacts, possible outcomes, and current challenges in terms of economic, environmental, and ethical aspects. Further outlooks in improving nanomedicine therapeutic efficacy are also discussed, including switching approaches to nanomedicine development, modifying current regulatory guidelines, and providing training programs. Nanomedicine ; Medicine ; Epidemiology ; Intensive care medicine ; Internal medicine ; Nanotechnology Nanoparticle-Based Drug Delivery ; Graphene and Nanomaterials Applications ; Cancer Research and Treatment
Authors: Francisco Romero | Luis Suárez | Sara Díaz | Zaida Ortega
Source: Polymer Composites (article, 2024-12-17)
Field: Materials Science — Polymers and Plastics

Rotomolded polypropylene‐ignimbrite composites: Giving a second life to mineral dust wastes Abstract The possibility of rotomolding polypropylene (PP) composites with high loadings of a silica‐based dust of ignimbrite, a byproduct of volcanic stone extraction is demonstrated. This study aims to establish the properties of composites with various ratios of mineral dust as a filler in PP matrices at loadings from 5 to 30 wt%, ultimately transforming mining residues into a valuable resource for composite production and creating a value chain around the traditional mining industry. Once the composites were obtained, they were subjected to several characterization techniques to comprehensively assess their mechanical and thermal properties. In general, a high percentage of ignimbrite powder has resulted in a reduction in the mechanical properties of neat PP, although no significant changes were observed for composites at lower loadings. Furthermore, the incorporation of this mineral material modified the thermal properties of the PP, enhancing its thermal stability. The blending of the matrix and filler resulted in a reduction in both the melting crystallization temperatures for highly‐filled composites. Rotomolded items with good aesthetics, with stone‐like appearance, were obtained without any modification on the mineral dust or even without any melt compounding, therefore not increasing the energy consumption during the composites production. Highlights Composites production is a suitable strategy for valorization of mineral residues. Welded ignimbrite residual dust has been used for the first time in composites. Mineral dust has been successfully used in composites obtained by rotomolding. Polypropylene with up to 30% of the stone dust can be processed. Good aesthetics and mechanical features can be obtained with mineral wastes. Materials science ; Polypropylene ; Composite material ; Filler (materials) ; Compounding ; Mineral ; Composite number ; Metallurgy Polymer Nanocomposites and Properties ; Natural Fiber Reinforced Composites ; biodegradable polymer synthesis and properties
Authors: Sobhy M. Abdelkader | Donart Nayebare | Tamer F. Megahed | Ahmed M. R. Fath El‐Bab | Mohamed A. Ismeil | Omar Abdel‐Rahim
Source: PLoS ONE (article, 2024-07-11)
Field: Materials Science — Materials Chemistry

Development of low-cost micro-fabrication procedures for planar micro-thermoelectric generators based on thin-film technology for energy harvesting applications With the rapid proliferation of portable and wearable electronics, energy autonomy through efficient energy harvesting has become paramount. Thermoelectric generators (TEGs) stand out as promising candidates due to their silent operation, high reliability, and maintenance-free nature. This paper presents the design, fabrication, and analysis of a micro-scale TEG for powering such devices. A planar configuration was employed for its inherent miniaturization advantages. Finite element analysis using ANSYS reveals that a double-layer device under a 50 K temperature gradient generates an impressive open-circuit voltage of 1417 mV and a power output of 2.4 μW, significantly exceeding its single-layer counterpart (226 mV, 0.12 μW). Validation against the analytical model results yields errors within 2.44% and 2.03% for voltage and power, respectively. Furthermore, a single-layer prototype fabricated using paper shadow masks and sputtering deposition exhibits a voltage of 131 mV for a 50 K temperature difference, thus confirming the feasibility of the proposed design. This work establishes a foundation for developing highly efficient micro-TEGs for powering next-generation portable and wearable electronics. Miniaturization ; Electronics ; Energy harvesting ; Fabrication ; Thermoelectric generator ; Materials science ; Voltage ; Electrical engineering ; Optoelectronics ; Computer science ; Engineering physics ; Power (physics) ; Nanotechnology ; Thermoelectric effect ; Engineering ; Physics Advanced Thermoelectric Materials and Devices ; Innovative Energy Harvesting Technologies ; Energy Harvesting in Wireless Networks
Authors: Alessandro Zappi | Alessandra Biancolillo | Nicholas Kassouf | Valentina Marassi | Pietro Morozzi | Laura Tositti | Dora Melucci
Source: Analytica—A Journal of Analytical Chemistry and Chemical Analysis (article, 2024-05-08)
Field: Chemistry — Analytical Chemistry

Quantification of Recycled PET in Commercial Bottles by IR Spectroscopy and Chemometrics A novel approach for the quantification of recycled polyethylene terephthalate (r-PET) in commercial bottles is presented. Fifty-eight bottle samples from several brands and producers containing different percentages of r-PET were purchased from the market. Samples were analyzed by two spectroscopic methods: near-infrared (NIR) spectroscopy and attenuated total reflection (ATR) spectroscopy in the mid-infrared (MIR) region. No chemical pre-treatment was applied before analyses. The spectra were analyzed by partial-least squares (PLS) regression, and two models for NIR and MIR data were computed. Then, a multi-block regression was applied to join the two datasets. All models were validated by cross-validation and by excluding and projecting onto the model the replicated spectra of one sample at a time. Results demonstrated the potential of this approach, especially considering the variability of commercial samples in terms of additives, shape, or thickness of the bottles: for samples close to the centroids of the models (i.e., from 10 to 50% r-PET), the predictions of multi-block method seldom departed from the expected values of ±10%. Only for samples with 0% declared r-PET, the models showed poor prediction abilities. Chemometrics ; Bottle ; Partial least squares regression ; Polyethylene terephthalate ; Spectroscopy ; Materials science ; Infrared spectroscopy ; Analytical Chemistry (journal) ; Mathematics ; Statistics ; Chromatography ; Chemistry ; Composite material ; Physics Spectroscopy and Chemometric Analyses ; Advanced Chemical Sensor Technologies ; Spectroscopy Techniques in Biomedical and Chemical Research
Authors: Nianhong Chen | Yucheng Xia | Weiyan Wu | Siyu Chen | Mingming Zhao | Yanting Song | Yangyang Liu
Source: Frontiers in Medicine (article, 2024-05-09)
Field: Chemistry — Organic Chemistry

Exploring the mechanism of agarwood moxa smoke in treating sleep disorders based on GC–MS and network pharmacology AMS may alleviate sleep disorders by modulating cellular and synaptic signaling, controlling hormone and neurotransmitter pathways, etc. Understanding AMS's material basis and mechanism of action provides a foundation for future research on treating sleep disorders with AMS. According to the study, Agarwood Moxa Smoke (AMS) may improve sleep quality by modifying cellular and synaptic signaling pathways for those who suffer from sleep problems. This might lead to the development of innovative therapies with fewer side effects. PubChem ; KEGG ; Systems pharmacology ; Agarwood ; Computational biology ; Mechanism (biology) ; Pharmacology ; Traditional medicine ; Bioinformatics ; Biology ; Medicine ; Gene ontology ; Gene ; Genetics ; Gene expression ; Drug Wood and Agarwood Research ; Plant biochemistry and biosynthesis ; Traditional Chinese Medicine Analysis
Authors: Qi Wu | Wenhui Fan | Chong Qin | Xiaoqiang Jiang
Source: Physica Scripta (article, 2024-04-25)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Dual-parameter controlled reconfigurable metasurface for enhanced terahertz beamforming via inverse design method Abstract Recently, reconfigurable metasurfaces have emerged as a promising solution for wavefront manipulation in the terahertz (THz) region, providing enhanced beamforming capabilities. However, traditional single-parameter control methods fail to achieve independent phase and amplitude modulation, constraining their modulation capabilities. Meanwhile, forward design methods based on phase matching ignore the structural responses of the non-ideal unit, leading to degraded beamforming performance. Here, we introduce an electrically reconfigurable metasurface composed of bilayer graphene strips based on dual-parameter control. Full-wave simulations demonstrate independent amplitude and phase modulation, achieving the full 360° phase coverage and an adjustable amplitude range from 0 to 0.8 at 2.6 THz. To optimize beamforming performance, particularly for the responses of the non-ideal unit away from the designed frequency, we employed an inverse design method based on a hybrid evolutionary algorithm. This novel approach significantly enhances beam steering, achieving a maximum 60% increase in beam directivity and maintaining over 90% of ideal directivity across a broad frequency range from 1.6 THz to 5 THz. Especially, it achieves a maximum deflection angle of 75°. Meanwhile, the adaptability of the inverse design method is further demonstrated to various optimized objectives. For beam focusing, even with limited phase control (below 210°), this method significantly enhances the focusing quality (up to 150% enhancement) and increases the focusing efficiency from 25% to 40%. Additionally, it effectively mitigates the impact of quantized phase errors on beamforming. This research not only demonstrates potential applications in high-speed THz wireless communication and compact imaging systems but also paves the way for innovative designs in reconfigurable metasurfaces. Terahertz radiation ; Beamforming ; Directivity ; Computer science ; Amplitude modulation ; Wavefront ; Modulation (music) ; Optics ; Electronic engineering ; Materials science ; Frequency modulation ; Physics ; Radio frequency ; Acoustics ; Telecommunications ; Engineering ; Antenna (radio) Metamaterials and Metasurfaces Applications ; Antenna Design and Analysis ; Millimeter-Wave Propagation and Modeling
Authors: A. Lakshmana Rao | Raveesha Peeriga | Shabana Begum | Narender Gaddamedi | Bhaskar Vallamkonda | B. Anupama
Source: Journal of Applied Pharmaceutical Science (article, 2024-01-01)
Field: Chemistry — Analytical Chemistry

Novel bioanalytical LC-MS/MS method for determination of metoprolol in human plasma Our study describes a novel, fast, and accurate method for estimating metoprolol (MET) in human blood plasma using LC-MS/MS technique.To prepare the samples, we used MET d7 as an internal standard (ISTD) and isolated MET from plasma using a special LLE technique.Following evaporation and reconstitution, the samples were injected into a specific chromatography column.Using a technique called single reaction monitoring; we were able to detect MET and the ISTD without interference from other blood plasma components.MET produced a unique signal and the ISTD produced a slightly different but related signal.Our analysis showed a reliable relationship between the amount of MET and the signal strength (correlation coefficient 0.9956).This relationship held true across a range of MET concentrations.Additionally, tests confirmed that MET remained stable in blood plasma under various conditions, including room temperature storage, injector storage, freeze-thaw cycles, and long-term freezing.This newly developed method adheres to validation guidelines set by the USFDA.It can be effectively used to measure MET levels in blood plasma for both routine testing and pharmacokinetic studies. Bioanalysis ; Metoprolol ; Human plasma ; Chromatography ; Chemistry ; Analytical Chemistry (journal) ; Medicine ; Internal medicine Analytical Methods in Pharmaceuticals ; Pesticide Residue Analysis and Safety ; Pharmacological Effects and Assays
Authors: Francesc X. Espinach | Mario Monzón | Rubén Paz | Raquel Ortega | P. Fullana | Alba Bala | Cristiane Inácio de Campos | Marc Delgado‐Aguilar | Quim Tarrés
Source: Journal of Cleaner Production (article, 2024-11-22)
Field: Materials Science — Polymers and Plastics

Composites made of a blend of plastics recovered from bottle caps reinforced with fibers from banana rachis waste. A Circular Economy Strategy in the Canary Islands The application of the Circular Economy can be a key answer to sustainability strategies and can reach peak importance in the outermost regions like the Canary Islands due to their limitations in the treatment of agroforestry and municipal waste. This paper explores the application of Circular Economy in the Canary Islands polymer transformation industry. The authors explore a polymer blend from plastic bottle caps recovered from the selective waste recollection that can be reinforced with banana fibers from the pseudostem and the rachis of the plants. The paper shows the potential and the competitiveness of the blends and the composite materials. The authors have found that the polymer blend can be used as a substitute for high-density polyethylene. The results show that composite materials with reinforcement percentages equal to or higher than 30 wt% offer higher mechanical properties and are more cost-effective than plastic blends. The paper shows the opportunity to create value from urban and agroforestry waste and at the same time prevent the dumping of these subproducts. • Combining packaging and agroforestry wastes in new composites. • Technical and economic assessments show the feasibility of circular economy strategies. • Solving waste issues in remote Canary Islands through circular economy. • Possible use of recycled polymers and composites as HDPE substitute. Bottle ; Circular economy ; Materials science ; Composite material ; Pulp and paper industry ; Engineering ; Biology ; Ecology Natural Fiber Reinforced Composites ; Additive Manufacturing and 3D Printing Technologies ; biodegradable polymer synthesis and properties
Authors: Héléna Verbeeck | Vincent Feyen | Inge Bellemans | Nele Moelans
Source: Computational Materials Science (article, 2024-08-22)
Field: Materials Science — Materials Chemistry

Multi-phase-field modeling of the dissolution behavior of stoichiometric particles on experimentally relevant length scales Dissolution ; Stoichiometry ; Field (mathematics) ; Phase (matter) ; Materials science ; Phase field models ; Chemical physics ; Thermodynamics ; Chemistry ; Physics ; Physical chemistry ; Mathematics Solidification and crystal growth phenomena ; Metallurgical Processes and Thermodynamics ; Aluminum Alloy Microstructure Properties
Authors: Ke Nong | Si Chen | Zhiyong Jason Ren | Min Zeng
Source: Minerals (article, 2024-12-11)
Field: Materials Science — Biomaterials

Analysis of Glauconite Research Trends Based on CiteSpace Knowledge Graph This paper aims to explore the current status and development trend of glauconite research through CiteSpace (version 6.2.R3) software tools. Based on the literature records from 1980 to 2024 in the Web of Science Core Collection database, this study visualizes the countries/regions, institutions, authors, journals, literature, and keywords related to glauconite. The results show that the United States, Russia, India, France, and England are the main contributing countries to glauconite research, the Russian Academy of Sciences is the institution with the largest number of publications, and Santanu Banerjee and Gilles S. Odin are the most influential authors. The field of glauconite has a high degree of international cooperation and multidisciplinary cross-disciplinary nature. The research hotspots of glauconite are also identified, including origin, basin, sediments, geochemistry, sandstone, and climate, and emerging research frontiers such as fertilizer, removal, provenance, composition characteristics, and Fe are pointed out. Glauconite research is not only of great significance in the field of geology, but its application potential in environmental management and agricultural development is also gradually being recognized, indicating that this field has broad research and application prospects in the future. Glauconite ; Provenance ; Multidisciplinary approach ; Earth science ; Web of science ; Geography ; Regional science ; Library science ; Archaeology ; Social science ; Political science ; Geology ; Geochemistry ; Sociology ; Computer science Clay minerals and soil interactions ; Chemical Synthesis and Characterization ; Iron oxide chemistry and applications
Authors: W. Liu | Fuyan Wu | Zao Yi | Yongjian Tang | Yougen Yi | Pinghui Wu | Qingdong Zeng
Source: Molecules (article, 2024-09-23)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Broadband Solar Absorber and Thermal Emitter Based on Single-Layer Molybdenum Disulfide In recent years, solar energy has become popular because of its clean and renewable properties. Meanwhile, two-dimensional materials have become a new favorite in scientific research due to their unique physicochemical properties. Among them, monolayer molybdenum disulfide (MoS<sub>2</sub>), as an outstanding representative of transition metal sulfides, is a hot research topic after graphene. Therefore, we have conducted an in-depth theoretical study and design simulation using the finite-difference method in time domain (FDTD) for a solar absorber based on the two-dimensional material MoS<sub>2</sub>. In this paper, a broadband solar absorber and thermal emitter based on a single layer of molybdenum disulfide is designed. It is shown that the broadband absorption of the absorber is mainly due to the propagating plasma resonance on the metal surface of the patterned layer and the localized surface plasma resonance excited in the adjacent patterned air cavity. The research results show that the designed structure boasts an exceptional broadband performance, achieving an ultra-wide spectral range spanning 2040 nm, with an overall absorption efficiency exceeding 90%. Notably, it maintains an average absorption rate of 94.61% across its spectrum, and in a narrow bandwidth centered at 303 nm, it demonstrates a near-unity absorption rate, surpassing 99%, underscoring its remarkable absorptive capabilities. The weighted average absorption rate of the whole wavelength range (280 nm-2500 nm) at AM1.5 is above 95.03%, and even at the extreme temperature of up to 1500 K, its heat radiation efficiency is high. Furthermore, the solar absorber in question exhibits polarization insensitivity, ensuring its performance is not influenced by the orientation of incident light. These advantages can enable our absorber to be widely used in solar thermal photovoltaics and other fields and provide new ideas for broadband absorbers based on two-dimensional materials. Molybdenum disulfide ; Materials science ; Optoelectronics ; Absorption (acoustics) ; Renewable energy ; Optics ; Composite material ; Physics Metamaterials and Metasurfaces Applications ; Thermal Radiation and Cooling Technologies ; Plasmonic and Surface Plasmon Research
Authors: V. VINȚELER | Roxana Dudric | Rareș Bortnic | Ádám Szatmári | Lucian Barbu–Tudoran | Romulus Tetean
Source: Romanian Journal of Physics (article, 2024-09-15)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Synthesis and Characterization of CoFe2O4 Nanoparticles and CoFe2O4@BaTiO3 Nanocomposites for Biomedical Applications Cobalt ferrite magnetic nanoparticles (CFO) of around 9 nm were synthesized with the solvothermal method. The CFO particles were covered with a barium titanate (BTO) shell at a 1:1 CFO:BTO ratio, via a sol-gel synthesis, to form CFO@BTO nanocomposites. X-Ray Diffraction (XRD) studies reveal the presence of only the expected CFO and BTO phases. Scanning and Transmission Electron Microscopy (SEM, TEM) images show the thorough covering with the BTO shell. Energy-Dispersive X-ray spectroscopy (EDX) mapping was used to analyze the elemental composition of the nanocomposites. Magnetic characterization shows high saturation magnetization and low coercive field at 300 K, suitable for biomedical applications. Characterization (materials science) ; Nanoparticle ; Nanocomposite ; Physics ; Nanotechnology ; Materials science Multiferroics and related materials ; Ferroelectric and Piezoelectric Materials ; Magnetic Properties and Synthesis of Ferrites