jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Yi Chen | Yu Bai | Heng Zhang | Zheng Zhou
Source: STEMedicine (article, 2022-09-08)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Plasmonic nanoassemblies for surface-enhanced Raman scattering-based biodetection and biomedical theranostics Plasmonic nanoassemblies are well-defined organizing of elementary metallic nanocrystal building blocks into ordered architectures across multiple scales, which constituents an exciting route to engineer nanomaterials structures with novel properties. Such nanoassemblies can accurately enhance, guide, and switch electromagnetic field at the nanoscale, which is shaping new-generation technologies with a plethora of applications, such as ultrasensitive bimolecular sensors, cancer diagnostics, and photothermal therapy (PTT), to name a few. In this review, we mainly focus on the plasmonic nanoassemblies, including the structure design, property control, and biomedical applications. The guiding principles have been first clarified with design rules being suggested. Then, the methodologies for fabrication of surface-enhanced Raman scattering-based (SERS-based) biodetection devices have been discussed. Finally, we summarized the PTT by using the plasmonic nanoassemblies as bioprobes for theranostics. Based on the facile yet efficient fabrication methods, high-efficient optoelectronic properties, and high performance in biomedical applications, we firmly believe that the plasmonic nanoassemblies can be integrated with portable devices for next-generation biosensors and biomedical theranostics. Nanotechnology ; Plasmon ; Materials science ; Photothermal therapy ; Raman scattering ; Biosensor ; Nanomaterials ; Fabrication ; Raman spectroscopy ; Optoelectronics ; Optics ; Physics Gold and Silver Nanoparticles Synthesis and Applications ; Advanced biosensing and bioanalysis techniques ; Biosensors and Analytical Detection
Authors: Yongdong Wang | Kai Liu | Jie Wang | Chufan Qi | Yuanyuan Chen | Shi Chen | Pengxin Du | Tianyue Zhou
Source: Research Square (preprint, 2022-10-28)
Field: Materials Science — Biomaterials

Crystallization rate model of tunnel drainage pipes in karst areas Abstract The crystallization blockage of the tunnel drainage pipes in karst areas often threatens the normal construction of tunnels and affects operation of drainage systems. Based on basic theory of CaCO3 crystallization, this study analyses the law of the crystalline scale formation rate of tunnel drainage pipes in karst areas through three mass transfer mechanisms: convective mass transfer, molecular diffusion and wall ion reactions, obtains the calculation model of crystalline scale formation rate of drainage pipes, and verifies model by simulating crystalline scale formation tests of tunnel drainage pipes. The results show that factors such as the flow rate of karst water, the inner diameters of tunnel drainage pipes, the molecular diffusion coefficient, the dynamic viscosity of karst water, the molecular diffusion coefficient of calcium carbonate, the temperature of karst water, and the slopes of tunnel drainage pipes have certain influences on the crystallization of the tunnel drainage pipes in karst areas, and they promote or inhibit the formation of scale layers on the inner walls of the tunnel drainage pipes in karst areas by affecting the efficiency of convective mass transfer, molecular diffusion and wall ion reactions; under different test conditions, the average relative errors between the calculated results of the crystalline scale formation rate of drainage pipes and those of the pipes in the test group are 9.1%, 13.7%, 14.2% and 16.1% respectively. Considering the scouring effect of water flow on crystalline scale layers, although there are certain errors in the results, this does not affect the overall results Drainage ; Karst ; Diffusion ; Crystallization ; Geology ; Molecular diffusion ; Volumetric flow rate ; Mass transfer ; Geotechnical engineering ; Materials science ; Mechanics ; Chemistry ; Thermodynamics ; Engineering Calcium Carbonate Crystallization and Inhibition ; Karst Systems and Hydrogeology ; Grouting, Rheology, and Soil Mechanics
Authors: Yi Jiang | Han Qingqing | Zhaoen Dai | Chao Zhou | Jianfeng Yu | Chunjian Hua
Source: Research Square (preprint, 2022-01-18)
Field: Materials Science — Materials Chemistry

Structural Design and Kinematic Analysis of a Welding Robot for Liquefied Natural Gas Membrane Tank Automatic Welding Abstract Owing to the complex structures of welding materials, special welding conditions, and challenges during the automatic welding of the liquefied natural gas (LNG) ship Mark III’s membrane tank, a series–parallel–series hybrid structure mobile welding robot having sufficient adaptability for welding corrugated plates in membrane tanks was designed in this study. The configuration of the hybrid robot had good workspace characteristics, and it could always maintain a certain distance and angle between the end of the welding torch and the weld line because of its detection and control system coordination. In this study, degrees of freedom, kinematic characteristics, workspace, and adaptability analyses were conducted for the hybrid mechanism. A simulation verification was performed, and a ripple-trajectory-following experiment was conducted using real objects. The simulation and experimental results showed that the welding robot had a reasonable mechanism design, smooth motion, and good terminal distance and angle control, thus meeting the requirements for automatic welding of corrugated plates in membrane tanks. Welding ; Robot welding ; Workspace ; Mechanical engineering ; Kinematics ; Robot ; Engineering ; Trajectory ; Computer science ; Artificial intelligence Silicone and Siloxane Chemistry ; Spacecraft and Cryogenic Technologies ; Soft Robotics and Applications
Authors: Chu Ngo | 、 Do | Thi Dung | Lieyang Li | Hiroshi Masuda | Hidenobu Murata | Atsushi Nakahira | Hidehiro Yoshida
Source: Journal of the Japan Society of Powder and Powder Metallurgy (article, 2022-04-14)
Field: Materials Science — Materials Chemistry

2022年度春季大会プログラム Fabrication of high-strength multilayered alumina Geology Anodic Oxide Films and Nanostructures ; Advanced ceramic materials synthesis ; Bauxite Residue and Utilization
Authors: Thuy Dung Luong Thi | Tuan Nguyen Anh | Thuc Nguyan Van | Hoan Nguyen Xuan | Nguyễn Xuân Viết
Source: Heavy metals and arsenic concentrations in water agricultural soil and rice in Ngan Son district Bac Kan province Vietnam (article, 2022-10-05)
Field: Chemistry — Analytical Chemistry

Electrochemical detection of Sudan based on Ni/Graphene modified screenprinted carbon electrode In the work reported here, the simple and efficient modification of Ni nanoparticles&amp;nbsp;/reduced graphene (rGO) on the surface of the screen-printed carbon electrode (SPCE) was&amp;nbsp;demonstrated. The obtained composited materials were characterized by physicochemical&amp;nbsp;methods such as SEM and electrochemical techniques. The results show that the Ni&amp;nbsp;nanoparticles are uniformly distributed on the surface of the reduced graphene material with&amp;nbsp;the particle size from 10 - 20 nm. The electrochemical properties show that the&amp;nbsp;Ni/rGO/SPCE material exhibits high electron exchange ability in 0.1 M KOH media. In&amp;nbsp;addition, the Ni/rGO composited material modified SPCE to form a Sudan electrochemical&amp;nbsp;sensor. The sensor has high sensitivity (9.13 &amp;micro;A. &amp;micro;M-1.cm-2), wide dynamic range (300 nM&amp;nbsp;- 35,000 nM) and low limit of detection - LOD (171.8 nM (3*&amp;sigma;). The combination of a&amp;nbsp;miniaturized 3-electrode system (12.5 mm x 4 mm x 0.3 mm) with a highly electrochemical&amp;nbsp;activity of Ni/rGO composited material pave the prospect for the creation of a new type of&amp;nbsp;electrical sensor: compact, high sensitivity in the analysis of Sudan I in particular and in the&amp;nbsp;analysis of banned substances in food in general. &amp;nbsp; Graphene ; Electrochemistry ; Materials science ; Electrode ; Nanoparticle ; Detection limit ; Nanotechnology ; Electrochemical gas sensor ; Chemical engineering ; Nuclear chemistry ; Chemistry ; Chromatography ; Physical chemistry Dye analysis and toxicity ; Electrochemical sensors and biosensors ; Advanced Chemical Sensor Technologies
Authors: Khin K. Z. Mon | Zhangyong Si | Mary B. Chan‐Park | Linda J. Kenney
Source: bioRxiv (Cold Spring Harbor Laboratory) (preprint, 2022-05-06)
Field: Chemistry — Organic Chemistry

Polyimidazolium protects against an invasive clinical isolate of <i>Salmonella</i> Typhimurium ABSTRACT Frequent outbreaks of Salmonella Typhimurium infection in both the animal and human population with potential for zoonotic transmission pose a significant threat to the public health sector. The rapid emergence and spread of more invasive multidrug-resistant clinical isolates of Salmonella further highlight the need for the development of new drugs with effective broad-spectrum bactericidal activities. Synthesis and evaluation of main-chain cationic polyimidazolium 1 (PIM1) against several gram-positive and gram-negative bacteria have previously demonstrated the efficacy profile of PIM1. The present study focuses on antibacterial and anti-biofilm activities of PIM1 against Salmonella both in vitro and in ovo setting. In vitro , PIM1 exhibited bactericidal activity against all tested three strains of Salmonella at a low dosage of 8 μg/ml. Anti-biofilm activity of PIM1 was evident with complete inhibition for the initial attachment of biofilms at 16 μg/ml and degradation of pre-formed biofilms in a dose-dependent manner. During the host cell infection process, PIM1 reduces extracellular bacterial adhesion and invasion rates to limit the establishment of infection. Once intracellular, the drug-resistant strain was tolerant and protected from PIM1 treatment. In a chicken egg infection model, PIM1 exhibited therapeutic activity for both Salmonella strains with stationary-phase and exponential-phase inocula. Moreover, PIM1 showed a remarkable efficacy against the stationary phase inocula of drug-resistant Salmonella by eliminating the bacteria burden in &gt;50% of infected chicken egg embryos. Collectively, PIM1 has demonstrated its potential as a drug candidate for treatment of Salmonella infections, as well as a solution to tackle egg contamination issues on poultry farms. Microbiology ; Salmonella ; PIM1 ; Biology ; Biofilm ; Drug resistance ; Bacteria ; Biochemistry Antimicrobial agents and applications ; Antimicrobial Peptides and Activities ; Bacteriophages and microbial interactions
Authors: E Songfeng | Ruixia Zhao | Doudou Ning | Qin Ma | Bo Geng | Jiayi Liu | Zhaoqing Lu
Source: Research Square (preprint, 2022-08-23)
Field: Materials Science — Biomaterials

Highly water-dispersed composite of cellulose nanofibers and boron nitride nanosheets Abstract In this work, a composite of cellulose nanofibers (CNFs) and boron nitride nanosheets (BNNSs) with high dispersity in water is prepared via the combination of ball-milling and high-pressure homogenization, which is then transformed into paper-like film by vacuum assisted filtering and drying. The obtained CNF/BNNS dispersions can stably exist over 30 days without the observation of sediments. CNFs as a medium of ball-milling can protect the exfoliated BNNSs from being reaggregation and severely destroyed in violent collisions, and the BNNSs and CNFs can promote their exfoliation with each other. The hydrophilicity and electrostatic repulsion of CNFs, as well as the strong interfacial interactions and stereo-hindrance effects between one-dimensional (1D) CNFs and two-dimensional (2D) BNNSs are the reasons for the high dispersity of the composite in water, which in turn results in the favorable mechanical properties of the formed films. Although the introduction of BNNSs lowers the stress, strain, and toughness of the neat CNF films, but increases their modulus due to the stiffness of BNNSs. However, the thermal conductivities of the homogenized samples are inferior to the unhomogenized ones, as the decreased lateral sizes and excellent dispersibility of BNNSs are unfavorable to the formation of connective path of thermal conduction. Boron nitride ; Nanofiber ; Cellulose ; Composite number ; Materials science ; Boron ; Chemical engineering ; Hexagonal boron nitride ; Composite material ; Nanotechnology ; Chemistry ; Graphene ; Organic chemistry ; Engineering Advanced Cellulose Research Studies ; Electrospun Nanofibers in Biomedical Applications ; Electromagnetic wave absorption materials
Authors: Alexandre Fromain
Source: Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) (preprint, 2022-07-20)
Field: Materials Science — Materials Chemistry

Bio-Nano-Transformation of nanoparticles in cells Les Nanoparticules magnétiques (Nps) suscitent un intérêt toujours plus croissant en biomédecine compte tenu de leurs caractéristiques multifonctionnelles, tels que magnétiques et optiques. Elles occupent une place prépondérante dans le développement de nouvelles méthodologies diagnostiques et thérapeutiques, tels que le ciblage et l'administration de médicaments, la thérapie génique, les thérapies thermiques contre le cancer ou la médecine régénérative. Avec l'avancement des développements sur l'utilisation des nanoparticules magnétiques dans le génie biomédical, notamment les thérapies cellulaires, la question de leur BioNanoTransformation en cellule reste cruciale. Je vous propose donc deux approches de l'étude de transformation subits par les Nanoparticules magnétiques dans les cellules. La première étant de suivre le devenir de Nps en thérapie thermique activées celles-ci. En effet, les nanoparticules d'oxyde de fer deviennent prépondérantes dans ce domaine car elles présentent une bonne biocompatibilité donnée par leur composition en noyau de fer qui peut intégrer le métabolisme du fer dans l'organisme, et ont également montré des performances photothermiques intéressantes dans la fenêtre biologique infrarouge. Ces Nanoparticules peuvent ainsi être utilisées pour le traitement du cancer via génération de chaleur après exposition à un laser, avant de subir des biotransformations lors de l'absorption cellulaire et confinement endosomal. La deuxième approche tourne autour de l'utilisation de nanoparticules de platine comme inducteur thermique pour un traitement en photothermie, et l'étude de son devenir. La troisième approche se base sur le constat que la biosynthèse de Nps magnétiques à été observés chez l'Homme. Des nanoparticules magnétiques ont été signalées dans le cerveau humain, ou encore la recristallisation de nanoparticules magnétiques, après dégradation, dans les cellules souches confirme que les cellules humaines sont capables d'une telle biosynthèse. Comme de nombreux mécanismes fondamentaux de la biominéralisation se trouvent dans la biominéralisation des magnétosomes bactériens, les bactéries magnétotactiques peuvent servir de modèle à la Néosynthèse de Nanoparticules magnétiques à base de Sel de Fer par les cellules. Nano- ; Nanoparticle ; Transformation (genetics) ; Nanotechnology ; Materials science ; Chemistry ; Biochemistry ; Composite material Nanoparticles: synthesis and applications
Authors: Xin Wu | Jack K. Clegg
Source: ChemRxiv (preprint, 2022-11-22)
Field: Chemistry — Spectroscopy

[2.2.2]Urea cryptand: an easily accessible neutral organic cage for anion binding in water Binding hydrophilic anions such as sulfate in water is a significant academic challenge, in particular for neutral receptors. To achieve this, typically a large molecular receptor is designed that wraps around a bound anion in a hydrophobic microenvironment. Such receptors require multi-step synthesis and often display selectivity towards hydrophobic anions such as iodide. We here report the one-pot synthesis of a [2.2.2]urea cryptand (cage) and its ability to bind sulfate in water with sub-millimolar affinity achievable by incorporation into micelles. Unlike existing neutral receptors, the cage has >10-fold selectivity for sulfate against hydrophobic anions even in pure water. The cage displays rare slow-exchange NMR responses to divalent anions in DMSO-water allowing for simultaneous analysis of multiple divalent anions in water analogous to an ion chromatography instrument. Our results demonstrate the pre-organization of strong directional NH hydrogen bond donors in a cage scaffold as a synthetically less-demanding, yet effective approach to achieving selective binding of hydrophilic anions in water. Chemistry ; Cryptand ; Divalent ; Urea ; Selectivity ; Hydrogen bond ; Iodide ; Inorganic chemistry ; Ammonium ; Sulfate ; Ion exchange ; Hydrophobic effect ; Combinatorial chemistry ; Ion ; Molecule ; Organic chemistry ; Catalysis Molecular Sensors and Ion Detection ; Supramolecular Chemistry and Complexes ; Luminescence and Fluorescent Materials
Authors: Mallikarjuna Patil | CT Ramachandra | Mahesh Kumar | G Suresha | Prasanna Kuma
Source: Indian Journal of Dairy Science (article, 2022-02-20)
Field: Materials Science — Materials Chemistry

Design and development of solid state cooling module for rawmilk cooling The global increasing demand for refrigeration in field of cooling and storage led to usage of more electricity and release of ozone depleting gases over the world which is a contributing factor of global warming. Thermoelectric cooling is a novel technique for producing cooling and heating effect. Hence, a solid state cooling module for cooling of raw milk was designed and developed. The milk cooling chamber was designed with the dimensions of 260 mm in diameter, 140 mm in height and 2 mm in thickness. The volume of the milk and water cooling chamber was 5 and 4 L, respectively. Three numbers of TEC1-12715 Peltier module, with the dimensions of 40 mm in length, 3.6 mm in thickness and 40 mm in width, cold side fins (36 fins), hot side fins (100 fins) and exhaust fans (3 Nos.) were used in the cooling module. The 12 V, 10A DC power supply for three module and exhaust fans was drawn from SMPS in parallel connection. The thermoelectric cooling module was able to cool raw milk from 37 to 9 Â°C. The highest cooling load obtained was 229.74 kJ at 60 min. The minimum and maximum power consumption recorded was 0.375 kWh and 1.125 kWh, respectively. The COP of the module was ranged from 0.036 to 0.259. Refrigeration ; Thermoelectric cooling ; Materials science ; Environmental science ; Water cooling ; Thermoelectric effect ; Nuclear engineering ; Mechanical engineering ; Engineering ; Thermodynamics ; Physics Advanced Thermoelectric Materials and Devices
Authors: Miji Yeo | Jung Won Yoon | Gyu Tae Park | Sung‐Chan Shin | Young‐Cheol Song | Yong-Il Cheon | Byung‐Joo Lee | GeunHyung Kim | Jae Ho Kim
Source: Research Square (preprint, 2022-05-31)
Field: Materials Science — Biomaterials

Acceleration of Esophageal Wound Healing by Anisotropically Aligned Smooth Muscle Cell-Laden Nanofibrous Patch Abstract Background Esophageal tissue engineering is proposed to repair damaged esophagus, which requires peristalsis via directional alignment and movement of smooth muscle. Cell electrospinning (CE) is an effective technique to produce aligned muscle tissues by directly encapsulating living cells into micro/nanofibers. Mesenchymal stem cells (MSCs) can differentiate into smooth muscle cells (SMCs) in response to treatment with transforming growth factor-β1. In this study, we investigated the phenotypic changes of MSCs and MSC-derived SMCs via CE, and evaluated the therapeutic effect of SMC-patch for esophageal wound model. Methods MSCs and SMCs were fabricated with 2 wt % alginate and 3 wt % PEO, and the cell-laden bioink was printed and electrospun onto PCL scaffolds for random and anisotropic alignment, respectively. In in vivo test, the SMC-patch was construct by CE and the rat’s esophageal wound model was developed by tissue punching. The SMC-patch was transplanted with sutures in the esophageal defect. Results Cell electrospinning resulted in more aligned and elongated forms of MSCs and SMCs than bioprinting. SMCs aligned via cell electrospinning exhibited upregulated expression of SMC-specific markers (alpha-smooth muscle actin, calponin, SM22α, and desmin), SMC-associated extracellular matrix proteins (fibronectin, collagen types I and IV), and connexin 43, the principal gap junction protein in SMCs. The electrospun SMC was fabricated in a patch form and transplanted into a rat esophageal wound model. Transplantation of the smooth muscle patch promoted muscle regeneration and vascularization in esophageal wounds. Conclusion Taken together, these results suggest that transforming growth factor-β1-induced differentiation of MSCs to SMCs and anisotropic alignment of SMCs can be applied to engineer smooth muscle tissues and treat gastrointestinal perforation. Acceleration ; Wound healing ; Smooth muscle ; Biomedical engineering ; Materials science ; Nanotechnology ; Physics ; Medicine ; Surgery ; Classical mechanics ; Internal medicine Electrospun Nanofibers in Biomedical Applications ; Tissue Engineering and Regenerative Medicine ; Hydrogels: synthesis, properties, applications
Authors: Jean‐Luc Rukundo | Jessica Latimer | Shiv Jain | Sven Kochmann | Sergey N. Krylov
Source: ChemRxiv (preprint, 2022-12-15)
Field: Chemistry — Spectroscopy

Streamlined Data Processing for Determination of Kd with "Accurate Constant via Transient Incomplete Separation" (ACTIS) The determination of accurate equilibrium dissociation constants Kd of protein–small molecule complexes is important but challenging as all established methods have inherent sources of inaccuracy. ACTIS is a new method for Kd determination using transient incomplete separation of the complex from the unbound small molecule in a pressure-driven flow inside a capillary. ACTIS is accurate and its accuracy is invariant to variations in geometries of both the fluidic system and the flow. Furthermore, ACTIS is implemented using a simple fluidic system supporting its accuracy and providing a simple-to-follow/copy template for instrumentation. Despite the simple and robust instrumentation/acquisition, the current data processing workflow is cumbersome, time-consuming, and prone to hard-to-trace human errors therefore hindering ACTIS’ ability to become a practical reference method for Kd determination. This technical note describes a streamlined workflow for processing ACTIS data; the workflow is implemented as a set of open-source software tools called prACTISed (https://github.com/prACTISedProgram/prACTISed). These tools allow all steps of data processing to be performed in fast and straightforward fashion. These practical software tools complement the simple instrumentation serving both developers and users of ACTIS. Workflow ; Computer science ; Instrumentation (computer programming) ; Software ; Fluidics ; Transient (computer programming) ; Data processing ; Data mining ; Computational science ; Real-time computing ; Algorithm ; Programming language ; Engineering ; Database Mass Spectrometry Techniques and Applications ; Analytical chemistry methods development ; Microfluidic and Capillary Electrophoresis Applications