jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Kabiru Bashir Ahmad | Emmanuel Kinsley Chinedu | REUBEN PAMBANI | Ansar Bilyaminu Adam | Musa Yahaya Abubakar | Ruslan Shamsuddeen
Source: African Multidisciplinary Journal of Sciences and Artificial Intelligence (article, 2024-07-31)
Field: Chemistry — Inorganic Chemistry

Organocatalysis: A Revolutionary Approach in Organic Synthesis Organocatalysis has emerged as a powerful tool in organic synthesis, enabling the efficient and selective formation of complex molecules. This review highlights the recent advances in organocatalysis, including the development of new catalysts, reactions, and applications. The advantages and limitations of organocatalysis are discussed, and its potential for scalability and sustainability is evaluated. The review also explores the mechanistic insights and future directions in this field, demonstrating the versatility and impact of organocatalysis in modern organic synthesis. This paradigm shift not only addresses the pressing environmental challenges but also paves the way for more innovative and economically viable synthetic strategies. As a result, organic synthesis is poised to play a crucial role in advancing pharmaceuticals, materials science, and agrochemicals, driving forward a more sustainable and resilient chemical industry. Organocatalysis ; Organic synthesis ; Chemistry ; Enantioselective synthesis ; Organic chemistry ; Catalysis Asymmetric Hydrogenation and Catalysis
Authors: Estela de Domingo | M. Bardají | Gregorio García | Silverio Coco
Source: Dyes and Pigments (article, 2024-04-15)
Field: Chemistry — Organic Chemistry

Color modulation in organometallic dyes. Purple-colored acyclic carbenes derived from 2-isocyanoazulene gold(I) complexes Carbene ; Azulene ; Bathochromic shift ; Chemistry ; Photochemistry ; Isocyanide ; Hypsochromic shift ; HOMO/LUMO ; Fluorescence ; Medicinal chemistry ; Organic chemistry ; Molecule ; Catalysis Catalytic Alkyne Reactions ; N-Heterocyclic Carbenes in Organic and Inorganic Chemistry ; Synthesis and Properties of Aromatic Compounds
Authors: Fatema Tuz Zohera | Farahidah Mohamed | Abul Kalam Azad | May Kyaw Oo
Source: Journal of Pharmacy (article, 2024-07-31)
Field: Materials Science — Materials Chemistry

Fabrication, Applications and Future Prospects of Mesoporous Silica Nanoparticles In past decades, nanomedicine has become a prominent area of focus within the discipline of nanotechnology, eliciting significant anticipation within the field of biomedical research. Scientists are creating unique nanoparticles for diagnosis, utilising techniques for imaging as well as therapy applications using medication delivery techniques. Mesoporous silica nanoparticles (MSNs), a recent addition to this area, serve as a sterling example of innovative nanostructures that offer distinctive and exceptional features. These features make them valuable for developing drug delivery systems with consistent and positive advancements in preclinical. MSNs efficiently encapsulate, control, and sometimes deliver biologic agents intracellularly for clinical use due to their distinct physicochemical characteristics, such as high porosity, large surface area, adjustable pore size and dimensions, good biocompatibility, and significant loading capacity. In this article, we discuss the latest advancements in fabrication, their presumed usefulness in delivering medications, and their application as diagnostic tools. It has been demonstrated that silica can store and release therapeutics, such as antibiotics, in a sustained and controlled manner. The desirable properties of MSNs have been further enhanced by modifying the surface of the siliceous frameworks through incorporating supramolecular assemblies and various metal species and their conjugates. These substantial advancements in innovative colloidal inorganic nanocontainers have driven researchers to explore their use in novel applications, such as stimuli (light/ultrasound/ magnetic)-responsive delivery-associated therapies with exceptional in vivo performance. This article provides a brief overview of the fabrication of siliceous frameworks and discusses significant advances in the engineering of MSNs. The precise control of the shape, dimension, homogeneity, and dispersity of MSNs is crucial, as these characteristics are critical quality attributes necessary for regulatory approval. Currently, explicit FDA guidelines for developing nanomaterial-based formulations intended for diagnostic or therapeutic purposes are lacking. Therefore, establishing standardised protocols and techniques for the synthesis and characterisation of nanoparticles, particularly for their use as theranostics, is essential for future commercial potential. Mesoporous silica ; Nanotechnology ; Fabrication ; Nanoparticle ; Materials science ; Mesoporous material ; Computer science ; Chemistry ; Medicine Mesoporous Materials and Catalysis ; Catalytic Processes in Materials Science ; Gas Sensing Nanomaterials and Sensors
Authors: János Daru | Zsombor Gonda | Zoltán May | Zoltán Novàk | Gergely L. Tolnai
Source: ChemRxiv (preprint, 2024-04-01)
Field: Materials Science — Materials Chemistry

Guideline for Elucidating Catalysts In the last decades, numerous efforts have been made to replace metal catalysts with cheaper and earth-abundant alternatives or the complete exclusion of metals in cross-coupling reactions, maintaining high efficiency of the target transformation. However, follow-up studies often revealed the role of metal impurities in the catalytic process. Thus, active metal impurities lead to mechanistic misinterpretations, could initiate erroneous research directives, and can lead to severe reproducibility problems. Milestone precedents of impurity effect in cross-coupling reactions are well documented in the literature. Interestingly, this fallacy has occurred repeatedly over the years due to the lack of thorough mechanistic studies and the appropriate research study scheme for identifying the impurity effect. Herein, we propose a guideline elucidating the real catalyst of future catalytic transformations that could eliminate mechanistic misinterpretation and help exclude the role of impurities in novel catalytic processes. Although this guideline mainly focuses on problems related to trace transition metals, it also offers the base for more general catalyst research. Guideline ; Catalysis ; Computer science ; Business ; Chemistry ; Medicine ; Organic chemistry Catalytic Processes in Materials Science
Authors: Spencer Zhao | Kang Yong Loh | Jonathan Tyson | Chandan Kadur | Carolyn R. Bertozzi | Karl Deisseroth | Zhenan Bao
Source: ChemRxiv (preprint, 2024-12-26)
Field: Materials Science — Materials Chemistry

Genetically-targeted photocatalytic organic dyes for spatiotemporally controlled organic synthesis directed by specific living cells Catalytic reactions of a broad range of abiotic molecules and macromolecules are beyond the native capabilities of mammals. Natural enzymes from prokaryotes or plant-based eukaryotes have limited substrate scopes. Therefore, broadening the range of catalytic bond-forming reactions that function in physiological conditions would enable the syntheses of a vast array of molecules directly within biological systems. This approach may provide an alternative way to modulate cellular behaviors if such molecules can be synthesized with spatiotemporal control on specific cell types in living systems; furthermore, restricting synthesis to well-defined cells or cell-types would enable a potentially transformative approach of treating cells as separable reaction vessels within living organisms. Herein, we use genetic targeting to incorporate an organic photocatalytic dye onto specific cell types to enable in-situ light-controlled and spatially defined chemical synthesis of non-natural molecules. We demonstrate, for the first time, a photo-patterned organic coupling reaction in the extracellular matrix of living cells under dilute, aqueous, aerobic physiological conditions. A 6-fold contrast in reaction yield can be achieved between two adjacent HEK293FT cells with and without light exposure. The above photocatalysis can be initiated using mild confocal laser stimulation as low as 16 μW/mm2 at multiple wavelengths. Furthermore, the cell-type specific photocatalyzed C-H functionalization coupling reactions taking place on cell surfaces are used to demonstrate anabolic construction of non-natural products. The above findings lay an important foundation for developing future abiotic cell-type specific chemical syntheses in living organisms. Photocatalysis ; Organic synthesis ; Organic chemicals ; Chemistry ; Nanotechnology ; Environmental science ; Environmental chemistry ; Business ; Materials science ; Biochemistry ; Catalysis Photochromic and Fluorescence Chemistry ; Click Chemistry and Applications ; Chemistry and Chemical Engineering
Authors: J. Kumar | P. Kamaraj | P.A. Vivekanand | Govindasami Periyasami | Mostafizur Rahaman | Perumal Karthikeyan | U.T. Uthappa | Selvakumar Palaniappan
Source: International Journal of Polymer Science (article, 2024-01-01)
Field: Chemistry — Organic Chemistry

Design of Novel Poly(Propranolol) Acrylate and Methacrylate Polymers through Radical Polymerization for Antibacterial Activity and Metal Ion Absorption The monomer 1‐(isopropylamino)‐3‐(1‐naphthyloxy)‐2‐propanoacrylate (IANOPA) and monomer 1‐(isopropylamino)‐3‐(1‐naphthyloxy)‐2‐propanomethacrylate (IANOPMA) were synthesized by treating 1‐(isopropylamino)‐3‐(1‐naphthyloxy)‐2‐propanol with acryloylchloride/methacryloyl chloride. The above esterification reactions were carried out in the presence of triethylamine. By employing the free radical polymerization method, the synthesized monomers were converted into polymers by using an initiator 2, 2′‐azobisisobutyronitrile in the presence of nitrogen environment at 70 ± 2°C. The monomers and polymers were characterized by various techniques such as FT‐IR, UV, 1 H NMR, and 13 C NMR spectroscopic analyses. Further, differential scanning calorimetry (DSC) was used to estimate the glass transition temperature ( T g ). Gel permeation chromatography (GPC) was used to estimate the molecular weight of the polymers. In addition, monomer and polymer surfaces’ morphology was analyzed using SEM analysis. As a primary application, the effectiveness of synthesized monomers and polymers was explored as antibacterial agents against gram‐positive bacteria (Staphylococcus aureus) and gram‐negative bacteria (Pseudomonas aeruginosa) which were measured from their inhibitory zone diameters. Further, the synthesized polymers, poly‐IANOPA and poly‐IANOPMA, were utilized for the uptake ability study of heavy metal ions such as Zn 2+ , Cu 2+ , Ni 2+ , and Pb 2+ present in water sources by equilibrium method. Acrylate ; Methacrylate ; Materials science ; Metal ; Polymerization ; Polymer chemistry ; Absorption (acoustics) ; Metal ions in aqueous solution ; Polymer ; Composite material ; Monomer ; Metallurgy Antimicrobial agents and applications ; Advanced Polymer Synthesis and Characterization ; Photopolymerization techniques and applications
Authors: Juliet Kallon | John J. Bang | Ufana Riaz | Darlene K. Taylor
Source: Nanomaterials (article, 2024-11-14)
Field: Materials Science — Polymers and Plastics

Design of Thermo-Responsive Pervaporation Membrane Based on Hyperbranched Polyglycerols and Elastin-like Protein Conjugates This paper reports the development of a highly crosslinked hyper-branched polyglycerol (HPG) polymer bound to elastin-like proteins (ELPs) to create a membrane that undergoes a distinct closed-to-open permeation transition at 32 °C. The crosslinked HPG forms a robust, mesoporous structure (150-300 nm pores), suitable for selective filtration. The membranes were characterized by FTIR, UV-visible spectroscopy, SEM, and AFM, revealing their structural and morphological properties. Incorporating a synthetic polypeptide introduced thermo-responsive behavior, with the membrane transitioning from impermeable to permeable above the lower critical solution temperature (LCST) of 32 °C. Permeation studies using crystal violet (CV) demonstrated selective transport, where CV permeated only above 32 °C, while water permeated at all temperatures. This hybrid HPG-ELP membrane system, acting as a molecular switch, offers potential for applications in drug delivery, bioseparations, and smart filtration systems, where permeability can be controlled by temperature. Pervaporation ; Elastin ; Conjugate ; Membrane ; Materials science ; Chemical engineering ; Polymer chemistry ; Chemistry ; Polymer science ; Biochemistry ; Permeation ; Engineering ; Medicine Dendrimers and Hyperbranched Polymers ; Membrane Separation and Gas Transport ; Covalent Organic Framework Applications
Authors: José Antonio Sánchez-Fernández | Rodrigo Cué-Sampedro | Hened Saade
Source: Preprints.org (preprint, 2024-04-19)
Field: Chemistry — Inorganic Chemistry

Supramolecular Systems Linked to Metal‐Organic Frameworks Supramolecular structures with specific applications are a pillar in several areas of science. Thus, from a contemporary point of view, there are several reasons to feel inclined to cover a systematic, or historic critique of the supramolecular concept itself. First, the idea of a supramolecular material seems more secure now than it was decades ago. Second, updating the interacting of MOFs and supramolecular chemical and conversely, supramolecularity to assemble MOFs and to make ef-ficient complex systems in multiple cutting-edge applications. Third, we should here simply confine to a consideration of how workers in this field have tried to correlate the notion of the idea of supramolecular systems linking self-assembly considerations. Thereby, this is clearly an ad-vantage that optimized geometries obtained on the conductive bases described that undoubtedly, some of these systems have substantial applications and create a significant practical interest. The outline of this review encompasses a general introduction to MOFs and supramolecularity, the key unit of the study presented here, followed by a survey of recent advances in supramolecular chemistry in confined space, relationships of MOFs with the supramolecular chemistry, electro-chemical synthesis of MOFs, and switchable MOFs. Finally, some discussion on possible future perspectives of this field is given. Supramolecular chemistry ; Metal-organic framework ; Nanotechnology ; Computer science ; Chemistry ; Materials science ; Organic chemistry ; Molecule Metal-Organic Frameworks: Synthesis and Applications
Authors: Tuba Iftikhar | Mali H. Rosnes
Source: Frontiers in Chemistry (review, 2024-08-29)
Field: Materials Science — Materials Chemistry

Covalent organic-inorganic polyoxometalate hybrids in catalysis Polyoxometalates (POMs) are a class of compounds known for the vast range of tunable structures and properties available, leading to applications in areas such as catalysis, energy, and advanced medicine. The ability to covalently functionalize POMs with organic components has been investigated extensively to tune the physical and chemical properties of the resulting hybrid materials. These hybrids, where the organic entity is covalently attached to the POM-core ( <b><i>Class II</i></b> hybrid POMs) result in a vast library of promising customizable catalytic systems, displaying tunable properties with a high level of synergy between the polyanion and the organic component. A number of <b><i>Class II</i></b> hybrids have been investigated for a wide range of catalytic applications, and here, we give a brief overview of <b><i>Class II</i></b> hybrids of the p-block elements and their applications in catalysis. Polyoxometalate ; Covalent bond ; Catalysis ; Hybrid material ; Chemistry ; Combinatorial chemistry ; Materials science ; Nanotechnology ; Organic chemistry Polyoxometalates: Synthesis and Applications ; Chemical Synthesis and Reactions ; Metal-Organic Frameworks: Synthesis and Applications
Authors: Zerui Chen | Lance J. Twyman
Source: ACS Applied Polymer Materials (article, 2024-04-02)
Field: Chemistry — Organic Chemistry

Synthesis of Fluorinated Amphiphilic Polymers and the Morphological Dependence on Their Oxygen Binding Capacity Water-soluble materials that can bind, sense, and deliver oxygen are important for several applications. These include catalysis, environmental sensors, smart packaging, agriculture, and medicine. Herein we report the synthesis of two related fluorinated amphiphilic polymers that can self-assemble into small micelles (20–30 nm) or larger vesicles (>300 nm). We found that the oxygen binding capacity of these polymers was dependent on the morphology of their self-assembled structures. At a constant fluorine concentration of 1.5 mg/mL, the oxygen solubility within the vesicle solution was 55% higher than that measured in pure water and 25% higher than the corresponding micelle solution. The increased concentration of oxygen in the vesicle solution indicated a significantly higher level of oxygen binding, which was attributed to additional oxygen trapped within the vesicle’s aqueous interior. Amphiphile ; Polymer ; Oxygen ; Polymer chemistry ; Materials science ; Chemistry ; Chemical engineering ; Polymer science ; Organic chemistry ; Copolymer ; Engineering Advanced Polymer Synthesis and Characterization ; Analytical Chemistry and Sensors ; Advanced Sensor and Energy Harvesting Materials
Authors: Márton Szabados | Rebeka Mészáros | Dorina Gabriella Dobó | Zoltán Kónya | Ákos Kukovecz | Pál Sipos
Source: Nanomaterials (article, 2024-09-02)
Field: Materials Science — Materials Chemistry

Ball-Milling Enhanced UV Protection Performance of Ca2Fe-Sulisobenzone Layered Double Hydroxide Organic Clay Using a co-precipitation technique, the anionic form of sulisobenzone (benzophenone-4) sunscreen ingredient was incorporated into the interlayer space of CaFe-hydrocalumite for the first time. Using detailed post-synthetic millings of the photoprotective nanocomposite obtained, we aimed to study the mechanochemical effects on complex, hybridized layered double hydroxides (LDHs). Various physicochemical properties of the ground and the intact LDHs were compared by powder X-ray diffractometry, N<sub>2</sub> adsorption-desorption, UV-Vis diffuse reflectance, infrared and Raman spectroscopy, scanning electron microscopy and thermogravimetric measurements. The data showed significant structural and morphological deformations, surface and textural changes and multifarious thermal behavior. The most interesting development was the change in the optical properties of organic LDHs; the milling significantly improved the UV light blocking ability, especially around 320 nm. Spectroscopic results verified that this could be explained by a modification in interaction between the LDH layers and the sulisobenzone anions, through modulated π-π conjugation and light absorption of benzene rings. In addition to the vibrating mill often used in the laboratory, the photoprotection reinforcement can also be induced by the drum mill grinding system commonly applied in industry. Layered double hydroxides ; Materials science ; Thermogravimetric analysis ; Hydroxide ; Chemical engineering ; Raman spectroscopy ; Diffuse reflectance infrared fourier transform ; Ball mill ; Nanocomposite ; Nanotechnology ; Composite material ; Photocatalysis ; Chemistry ; Organic chemistry ; Optics Layered Double Hydroxides Synthesis and Applications ; Magnesium Oxide Properties and Applications ; Inorganic Chemistry and Materials
Authors: Poonam Dwivedi | Mohammad Shahzad Samdani | Azhar U. Khan | Indu Jatrana | Sudhakar Bansod | Min Kim | Syed Najmul Hejaz Azmi | Mahboob Alam
Source: Nanotechnology Reviews (article, 2024-01-01)
Field: Materials Science — Materials Chemistry

Plant-mediated synthesis, characterization, and evaluation of a copper oxide/silicon dioxide nanocomposite by an antimicrobial study Abstract This study presents an innovative, environmentally friendly method for biosynthesizing copper oxide–silica (Cu 2 O/SiO 2 ) nanocomposites (CSNCs) utilizing an aqueous leaf extract of Callistemon viminalis ( C. viminalis ). The goal of this work is to fabricate CSNCs using a less hazardous and sustainable synthesis approach. Copper acetate and sodium metasilicate were used as precursors, whereas the C. viminalis green leaf extract was used as the reducing and stabilizing agent. Analysis of the plant extract using Fourier transform infrared spectroscopy indicated the presence of polyphenolic compounds, primarily phenolic acids, which functioned as both reducing and stabilizing agents in the synthesis of CSNCs. A combination of energy dispersive X-ray spectroscopy and scanning electron microscopy was used to study the formation of spherical copper–silica hybrid nanostructures. Powder X-ray diffraction analysis revealed the successful integration of silica with copper( i ) oxide (Cu 2 O) through the presence of distinct Cu 2 O peaks and a broad amorphous SiO 2 peak at 2 θ = 22.77°. The thermal stability of the nanocomposites (NCs) was assessed using thermogravimetric analysis and differential thermal analysis under a nitrogen atmosphere. The biogenic NCs also successfully inhibited pathogenic strains of Staphylococcus aureus ( S. aureus ) and Candida albicans ( C. albicans ); however, S. aureus was found to be more susceptible to the biocidal activity of the NCs than P. aeruginosa . These findings suggest that this simple, cost-effective, and eco-friendly method for producing biologically active hybrid nanomaterials holds significant promise for future applications in both biological and materials sciences. Nanocomposite ; Silicon dioxide ; Antimicrobial ; Copper ; Characterization (materials science) ; Copper oxide ; Materials science ; Silicon ; Oxide ; Nanotechnology ; Chemistry ; Inorganic chemistry ; Organic chemistry ; Metallurgy Nanoparticles: synthesis and applications ; Copper-based nanomaterials and applications ; TiO2 Photocatalysis and Solar Cells
Authors: Hui Yang | Yiming Li | Jinhui Hu | Dongxia Shi | Yongkang Ge | Jiwei Feng | Hongting Sheng | Manzhou Zhu
Source: Nano Research (article, 2024-12-25)
Field: Materials Science — Materials Chemistry

Atomically precise Pd <sub>8</sub> nanocluster encapsulated in a hierarchically engineered nanoreactor towards enhanced catalysis Metal-organic frameworks (MOFs) have emerged as superior hosting matrices for atomically precise nanoclusters (NCs) encapsulation, offering excellent physical and chemical protections for advanced catalysis. Nevertheless, the MOF coating significantly reduces the NC catalytic efficiency due to the diffusion barriers and the confined microenvironments. Herein, a hierarchically engineered MOF nanoreactor was constructed by controlled structural etching for NC immobilization. This nanoreactor possesses hierarchical pores to accelerate the diffusion rate of reactants and creates hollow structures to unleash the confined NC molecules from the rigid MOF network to a capacious microenvironment. The enhanced mass transfer, improved freedom of NCs, and outstanding stability collectively boosted the catalytic activity of the nanoreactor. By controlling the etching time, freestanding Pd<sub>8</sub>@zeolitic imidazolate framework-8 (ZIF-8)-TA<sub>10</sub> displayed a catalytic efficiency that was 3.17 times greater than that of the initial confined Pd<sub>8</sub>@ZIF-8 and even better than free Pd<sub>8</sub>. This work opens a new strategy to reduce the inherent limitations of porous matrixes for developing high-performance catalysts. Nanoreactor ; Catalysis ; Nanotechnology ; Materials science ; Nanoparticle ; Chemistry ; Organic chemistry Nanocluster Synthesis and Applications ; Nanomaterials for catalytic reactions ; Gold and Silver Nanoparticles Synthesis and Applications