jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Zahra Ahmadi | Hamed Saghaei | Mohammad Pasdari-Kia | Haddi Ahmadi | Nasrin Razmjooei | Farzaneh Sadat Ghoreishi | Kazem Zafari | Kamalodin Arik | Hamid Nezamdoost | Mahdi Nooshyar | Homayoon Oraizi
Source: Scientific Reports (article, 2025-02-19)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Self-reactive impedance surfaces for enhanced quasi-line wave propagation in the terahertz spectrum Quasi-line waves represent a distinct class of propagation modes along non-complementary impedance surfaces, offering an alternative to the conventional line waves typically formed by complementary impedance surfaces. In this study, we introduce a novel design for quasi-line waves utilizing non-dual, purely inductive impedance structures. By incorporating multilayer graphene, our design achieves wide bandwidth and extended propagation lengths in the terahertz range, with field concentration localized at the edges of the inductive surfaces. This configuration enables unidirectional wave propagation, with graphene integration providing precise control over bandwidth and transmission characteristics. Unlike traditional line waves, which are constrained to specific terahertz frequency ranges, our quasi-line mode-guided by self-inductive impedance surfaces-demonstrates significantly broader bandwidth and enhanced electric field intensity. The performance of this mode is strongly influenced by capacitance variations between impedance surfaces, exceeding the singularity limitation of conventional line waves. Our proposed structure demonstrates superior performance in both bandwidth and mode singularity within the terahertz spectrum, surpassing traditional line wave designs. Terahertz radiation ; Electrical impedance ; Line (geometry) ; Spectrum (functional analysis) ; Electromagnetic spectrum ; Optoelectronics ; Acoustics ; Physics ; Materials science ; Optics ; Mathematics Metamaterials and Metasurfaces Applications ; Advanced Antenna and Metasurface Technologies ; Plasmonic and Surface Plasmon Research
Authors: Fengrong Zhang | Luxing Liu | Cuilan Zhang | Dawei Shang | Lishun Wu
Source: Scientific Reports (article, 2025-01-20)
Field: Materials Science — Materials Chemistry

Preparation of ZnAl layered double hydroxides supported by silica for the treatment of Cr(VI) and Cu(II) in aqueous solution A novel adsorbent ZnAl-LDHs/SiO<sub>2</sub> (ZA/SiO<sub>2</sub>) was prepared by blending urea mixture of ZnSO<sub>4</sub> and Al<sub>2</sub>(SO<sub>4</sub>)<sub>3</sub> while using SiO<sub>2</sub> as a support form. The adsorption properties of ZA/SiO<sub>2</sub> for the removal of toxic metal ions (Cu(II) and Cr(VI)) from water were evaluated. By batch experiment method to investigate the ZA/SiO<sub>2</sub> adsorption of Cu(II) and Cr(VI) solution treatment effect. The sorption kinetics curves of Cu(II) and Cr(VI) on ZA/SiO<sub>2</sub> were L-shaped. What's more, the solid concentration effect was found in the process of sorption kinetics. Langmuir and Freundlich sorption isotherm models were used to analyze the adsorption data. The results showed that the adsorption conforms to Langmuir and Freundlich adsorption isotherm models. However, the adsorption capacity of ZA/SiO<sub>2</sub> compounds for Cu(II) and Cr(VI) is greatly improved. The adsorption capacity of Cu(II) is 158 mg·g<sup>-1</sup> and of Cr(VI) is 176 mg·g<sup>-1</sup>, which were 3.6 and 1.8 times of ZnAl-LDHs (ZA), respectively. Density functional theory (DFT) was utilized for the analysis of intrinsic mechanism and specific pathways. The primary mechanism for removing Cr(VI) from water mainly included the intercalation of Cr<sub>2</sub>O<sub>7</sub><sup>2-</sup> and exchange between Cr<sub>2</sub>O<sub>7</sub><sup>2-</sup> and OH<sup>-</sup>, excluding Cr(OH)<sub>3</sub> precipitation. Regarding the primary mechanism for eliminating Cu(II) from water, it involves isomorphic substitution as the predominant process, except for the formation of Cu(OH)<sub>2</sub> precipitates. Adsorption ; Aqueous solution ; Freundlich equation ; Sorption ; Chemistry ; Langmuir ; Ion exchange ; Intercalation (chemistry) ; Langmuir adsorption model ; Kinetics ; Precipitation ; Inorganic chemistry ; Layered double hydroxides ; Metal ; Nuclear chemistry ; Ion ; Physical chemistry ; Organic chemistry Layered Double Hydroxides Synthesis and Applications ; Adsorption and biosorption for pollutant removal ; Nanomaterials for catalytic reactions
Authors: Petar Petrov | Slavena Davidova | Galina Satchanska
Source: Polymers (review, 2025-04-25)
Field: Materials Science — Biomaterials

Polymer Micelles as Nanocarriers of Bioactive Peptides Bioactive peptides (BPs) have demonstrated diverse inhibitory effects against parasites, viruses, bacteria, fungi, and other pathogens, and therefore, they have been extensively used for developing various therapeutics. However, several challenges for the clinical use of BPs related to their stability, bioavailability, and cytotoxicity remain. The encapsulation of BPs in polymer micelles (PMs) has emerged as an effective strategy that can improve the pharmacological profiles, safety, and efficacy of treatments. This review describes the recent advances of micellar carriers of peptides with antimicrobial, anticancer, anti-inflammatory, immunomodulatory, and anti-diabetic activities. The mode of action of BPs and the unique characteristics of PMs are described, and a critical evaluation of their advantages and disadvantages is made. The upcoming challenges and future perspectives of micellar systems carrying BPs are discussed as well. Nanocarriers ; Micelle ; Bioavailability ; Antimicrobial ; Chemistry ; Mode of action ; Nanotechnology ; Pharmacology ; Materials science ; Nanoparticle ; Biochemistry ; Medicine ; Organic chemistry ; Aqueous solution Nanoparticle-Based Drug Delivery ; Surfactants and Colloidal Systems ; Advanced Drug Delivery Systems
Authors: Gohar Ijaz Dar | Elisabet Xifré‐Pérez | Abel Santos | Lluı́s F. Marsal
Source: View (article, 2025-01-12)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Engineering of hierarchical nano‐convex polymer lattice SERS platforms by template replica‐assisted nanoimprinting Abstract The precise fabrication of arrays of gold and silver nanodots (Au&amp;Ag_NDs) to create plasmonic lattices on different substrates through cost‐effective, scalable approaches remains challenging. The aim of this research is to engineer a new class of hierarchical plasmonic lattices based on Au&amp;Ag_NDs generated on polymer substrates via template replica‐assisted nanoimprinting. This method harnesses a combination of nanopatterning via anodization, magnetron sputtering, and annealing to generate Au&amp;Ag_NDs hierarchical plasmonic lattices with tunable features at the nanoscale. These plasmonic lattices are explored as ultrasensitive surface‐enhanced Raman scattering (SERS) platforms for the detection of a model organic (rhodamine B [RhB]). These reproducible model platforms achieve remarkable enhancement to detect RhB molecules, with a low limit of detection of 10 −8 M. The enhancement field factor of 10 7 indicates that the developed plasmonic lattices are adequate for efficient and highly sensitive SERS detection. Plasmon ; Materials science ; Nanotechnology ; Nanodot ; Nanoscopic scale ; Raman scattering ; Nanolithography ; Fabrication ; Replica ; Nano- ; Raman spectroscopy ; Optoelectronics ; Optics ; Physics Gold and Silver Nanoparticles Synthesis and Applications ; Pickering emulsions and particle stabilization ; Polymer Surface Interaction Studies
Authors: Irene Melendo | Pilar Borja | Sara Fuertes | Antonio Martı́n | Violeta Sicilia
Source: Inorganic Chemistry (article, 2025-08-22)
Field: Materials Science — Materials Chemistry

Double-Decker Platinum Complexes: From Visible to NIR-II Luminescence The Pt(II) dinuclear compounds [{Pt(C^N)(μ-S^N)}<sub>2</sub>] [S^NH: 2-mercapto-1-methylimidazol; HC^N= 1-naphthalen-2-yl-1<i>H</i>-pyrazole (naph-pz, <b>2a</b>); benzo[<i>h</i>]quinoline (bzq, <b>2b</b>)] were obtained by reaction of the corresponding mononuclear precursor [Pt(C^N)Cl(S^NH)] (C^N: naph-pz <b>1a</b>, bzq <b>1b</b>) with NEt<sub>3</sub>. Then, <b>2a</b> and <b>2b</b> were reacted with aqueous HX (X: Cl, Br, I) in molar ratio 1:2 to give the corresponding oxidized derivatives [{Pt(C^N)(μ-S^N)X}<sub>2</sub>] (X = Cl <b>3a/b-Cl</b>, Br <b>3a/b-Br</b>, I <b>3a/b-I</b>). Their X-ray structures showed shorter Pt-Pt distances in the Pt<sub>2</sub>(III) complexes (<i>ca</i>. 2.7 Å) than in the Pt<sub>2</sub>(II) ones (<i>ca</i>. 3.0 Å) in agreement with the existence of a Pt-Pt bond. The photophysical properties were studied experimentally and theoretically by DFT and TD-DFT. The Pt<sub>2</sub>(II) complexes exhibit an emission in the visible region (640 nm <b>2a</b>, 685 nm <b>2b</b>) of mostly excimeric <sup>3</sup>ππ* and <sup>3</sup>MMLCT [dσ*(Pt<sub>2</sub>) → π* (C^N)] character respectively, while the Pt<sub>2</sub>(III) complexes emit in the NIR-II region with maxima reaching up to 1215 nm. The <sup>3</sup>XMMCT nature of these emissions justify the influence of both the axial ligand (X) and the overlap of the dz<sup>2</sup> orbitals on their energies; the latter being affected by the nature of the C^N and the bridging ligand. Chemistry ; Platinum ; Luminescence ; Visible spectrum ; Photochemistry ; Optoelectronics ; Organic chemistry ; Catalysis Luminescence and Fluorescent Materials ; Organic Light-Emitting Diodes Research ; Lanthanide and Transition Metal Complexes
Authors: Rudolf L. Z. Ganzoni | Sofie S. Bournons | Erick M. Carreira | Dimitri De Bundel | Ilse Smolders
Source: Medicinal Research Reviews (review, 2025-04-05)
Field: Materials Science — Materials Chemistry

A Bright Future for Photopharmaceuticals Addressing Central Nervous System Disorders: State of the Art and Challenges Toward Clinical Translation Photopharmacology is an innovative approach that uses light to activate drugs. This method offers the potential for highly localized and precise drug activation, making it particularly promising for the treatment of neurological disorders. Despite the enticing prospects of photopharmacology, its application to treat human central nervous system (CNS) diseases remains to be demonstrated. In this review, we provide an overview of prominent strategies for the design and activation of photopharmaceutical agents in the field of neuroscience. Photocaged and photoswitchable drugs and bioactive molecules are discussed, and an instructive list of examples is provided to highlight compound design strategies. Special emphasis is placed on photoactivatable compounds for the modulation of glutamatergic, GABAergic, dopaminergic, and serotonergic neurotransmission for the treatment of neurological conditions, as well as various photoresponsive molecules with potential for improved pain management. Compounds holding promise for clinical translation are discussed in-depth and their potential for future applications is assessed. Neurophotopharmaceuticals have yet to achieve breakthrough in the clinic, as both light delivery and drug design have not reached full maturity. However, by describing the current state of the art and providing illustrative case studies, we offer a perspective on future opportunities in the field of neurophotopharmacology focused on addressing CNS disorders. Neuroscience ; Serotonergic ; Glutamatergic ; Translation (biology) ; Dopaminergic ; Central nervous system ; GABAergic ; Computer science ; Neuromodulation ; Medicine ; Psychology ; Biology ; Glutamate receptor ; Dopamine ; Serotonin Photochromic and Fluorescence Chemistry ; Photoreceptor and optogenetics research ; Nanoplatforms for cancer theranostics
Authors: Mozan Hassan | Priya Yuvaraju | Abbas Khaleel | Sahar Mohsin
Source: International Journal of Nanomedicine (article, 2025-11-01)
Field: Materials Science — Biomaterials

Fabrication and Characterization of Electrospun Sr/Zn-Doped Nano-Hydroxyapatite-Collagen-PLGA Nanofibrous Scaffolds for Bone Tissue Engineering Collectively, these findings suggest that the 4% Sr/Zn-nHAp-collagen-PLGA electrospun scaffolds possess favorable structural, mechanical, and biological properties, making them promising candidates for orthopedic applications. Fabrication ; Tissue engineering ; Characterization (materials science) ; Electrospinning ; Biomaterial ; Nanofiber ; Biocompatibility Electrospun Nanofibers in Biomedical Applications ; Bone Tissue Engineering Materials ; Collagen: Extraction and Characterization
Authors: Irfan Tahir | Christopher M. Foley | Rachael A. Floreani
Source: Foods (article, 2025-07-19)
Field: Materials Science — Biomaterials

Whey Protein Isolate and β-Lactoglobulin-Modified Alginate Hydrogel Scaffolds Enhance Cell Proliferation for Cultivated Meat Applications Innovative changes to our current food system are needed, and one solution is cultivated meat, which uses modern engineering, materials science, and biotechnology to produce animal protein. This article highlights the advantages of incorporating whey protein isolate (WPI) and β-lactoglobulin (β-LG) into hydrogel networks to aid cell growth on cultivated meat scaffolds. The protein and polysaccharide (i.e., alginate) components of the scaffolds are food-grade and generally regarded as safe ingredients, enabling the transition to more food-safe, edible, and nutritious scaffolds. The impact of WPI and varying properties on cell performance was evaluated; alginate concentration and the addition of proteins into the hydrogels significantly altered their stiffness and strength. The results of this study demonstrate the innocuous nature of novel scaffolds and reveal enhanced cell proliferation on WPI and β-LG-modified groups compared to standard biomaterial controls. This work serves as a stepping stone for more comprehensive analyses of WPI, β-LG, and alginate scaffolds for use in cultivated meat research and production. Whey protein isolate ; Whey protein ; Food science ; Self-healing hydrogels ; Chemistry ; Biomaterial ; Cell growth ; Polysaccharide ; Biotechnology ; Biochemistry ; Biology Electrospun Nanofibers in Biomedical Applications ; 3D Printing in Biomedical Research ; Tissue Engineering and Regenerative Medicine
Authors: Veda B. Hacholli | M. R. Shubha | B. H. Prabhanajan | M. Lavanya | S. Pramod | Abhishek Kumar | Łukasz Szeleszczuk | Marcin Gackowski
Source: Molecules (review, 2025-10-23)
Field: Chemistry — Organic Chemistry

Coumarin Derivatives as Anticancer Agents: Mechanistic Landscape with an Emphasis on Breast Cancer Coumarin derivatives constitute a versatile small-molecule chemotype with broad anticancer potential. This narrative review synthesizes recent in vitro and in vivo evidence on coumarin-based scaffolds, emphasizing breast cancer and covering lung, prostate, and colorectal models. We summarize major mechanisms of action-including induction of apoptosis (caspase activation and BAX/BCL-2 balance), modulation of PI3K/Akt/mTOR signaling, inhibition of angiogenesis (VEGFR-2), interference with estrogen biosynthesis (aromatase/ER axis), chaperone targeting (Hsp90), and attenuation of multidrug resistance (efflux pumps/autophagy)-and highlight representative chemotypes (e.g., benzimidazole, triazole, furocoumarins, topoisomerase- and CDK-oriented hybrids). Where available, we contrast potency and selectivity across models (e.g., MCF-7 vs. MDA-MB-231; A549; PC-3; colon lines) and discuss structure-activity trends linking substituent patterns (heteroaryl linkers, judicious halogenation, polar handles) to pathway engagement. We also delineate translational gaps limiting clinical progress-selectivity versus non-malignant cells, incomplete pharmacokinetic and safety characterization, and limited validation beyond xenografts. Finally, we outline priorities for preclinical optimization: biology-aligned target selection with biomarkers, resistance-aware combinations (e.g., PI3K/mTOR ± autophagy modulation; MDR mitigation), and early integration of ADME/tox and PK/PD to confirm on-target exposure. Collectively, the evidence supports coumarins as adaptable, multi-target anticancer leads, particularly promising in hormone-dependent breast cancer while remaining relevant to other tumor types. Breast cancer ; Coumarin ; In vivo ; Autophagy ; Angiogenesis ; Drug discovery ; Drug ; Estrogen receptor Synthesis and biological activity
Authors: Michal Ďurfina | Nafiseh Babaei | Zuzana Vanovčanová | Jozef Feranc | Vojtech Horváth | Ida Vašková | Ján Kruželák | Roderik Plavec
Source: Preprints.org (preprint, 2025-04-29)
Field: Materials Science — Biomaterials

Bio-Based Polyhydroxyalkanoate (PHA) Blends for 3D Printing: Rheological, Mechanical, Biocompatibility, and Biodegradation Properties This study develops highly flexible, biodegradable polymer blends using bio-based polyhydroxyalkanoate (PHA) polymers for Fused Deposition Modeling (FDM) 3D printing. A Design of Experiments (DoE) approach optimized blend compositions by varying crystallinity levels of three PHAs, processed via twin-screw extrusion. Rheological analysis revealed that PHA blends exhibited 30–50% lower viscosity than PLA at low shear rates, ensuring improved processability. Tensile testing confirmed favorable mechanical properties, with elongation at break exceeding 2000%, significantly surpassing PLA (29%). Differential Scanning Calorimetry (DSC) indicated partial miscibility and crystallinity reductions of up to 50%, influencing printability. Optimized 3D printing parameters demonstrated minimal warping for blends with crystallinity below 18%, ensuring high-dimensional stability. In home-composting tests, PHA blends showed significant degradation within two months, whereas PLA remained intact. Scanning Electron Microscopy (SEM) confirmed microbial degradation. Cytotoxicity tests demonstrated that the blends were non-toxic, supporting applications in tissue engineering. These findings highlight the potential of PHA-based blends as sustainable, high-performance materials for biomedical, packaging, and environmental applications. Polyhydroxyalkanoates ; Biodegradation ; Biocompatibility ; Rheology ; Materials science ; Polymer science ; Chemical engineering ; Chemistry ; Composite material ; Organic chemistry ; Bacteria ; Metallurgy ; Engineering biodegradable polymer synthesis and properties ; Additive Manufacturing and 3D Printing Technologies ; Electrospun Nanofibers in Biomedical Applications
Authors: Liyuan Xiao | Xue Bai | Zhenlü Wang | Jingqi Guan
Source: Chemical Science (article, 2025-01-01)
Field: Materials Science — Materials Chemistry

Synergistic spin effects in medium-entropy Ni–Fe–Mn–Ce oxyhydroxides for seawater oxidation Efficient and durable oxygen evolution reaction (OER) electrocatalysis is essential for advancing sustainable seawater electrolysis. In this work, a high-performance Ni-Fe-Mn-Ce medium-entropy oxyhydroxide is constructed <i>via in situ</i> electrochemical reconstruction strategy for the OER. Guided by density functional theory (DFT), the effects of eight candidate fourth-metal elements (Al, Ce, Co, Cr, Cu, Sn, Zn, or Zr) on the electronic structure and reaction energetics of the NiFeMn(O)OH matrix are comprehensively investigated, revealing the unique advantages of Ce in optimizing intermediate adsorption energies and lowering the theoretical overpotential. The catalyst requires an overpotential of only 183 mV at 10 mA cm<sup>-2</sup> in 1 M KOH, while maintaining a low overpotential of 224 mV in alkaline seawater, along with excellent resistance to Cl<sup>-</sup> corrosion. <i>Operando</i> spectroscopic characterizations reveal dynamic valence evolution and charge redistribution among Ni<sup>4+</sup>, Fe<sup>3+</sup>, and Ce<sup>3+</sup>/Mn<sup>2+</sup> species, which contribute to stabilizing intermediate adsorption and promoting electron transfer. Further electronic structure analysis demonstrates a favorable d-band center near the Fermi level and pronounces spin polarization in the medium-entropy system, which synergistically enhance OER kinetics. This work highlights the potential of entropy engineering combined with theoretical guidance in the development of advanced multi-metallic electrocatalysts for efficient seawater splitting. Overpotential ; Oxygen evolution ; Electrocatalyst ; Electrochemistry ; Catalysis ; Density functional theory ; Adsorption ; Valence (chemistry) Advancements in Solid Oxide Fuel Cells ; Electrocatalysts for Energy Conversion ; Electrochemical Analysis and Applications
Authors: Dirk Hegemann | Martina Buchtelová | Paula Navascués | Lenka Zajı́čková | Anne Géraldine Guex
Source: Advanced Materials Interfaces (article, 2025-01-13)
Field: Materials Science — Biomaterials

Permanent Plasma Surface Functionalization of Internal Surface Areas Abstract Surface functionalization technologies of fibrous or porous materials are often considered relatively unstable with a shelf life of several weeks or months at most, evoked by heterogeneous treatment of their internal surface areas. Here, it is demonstrating that the fine balance of plasma etching, deposition, and oxidation involving different reactive species, strongly enhances penetration depth within complex structures. On this basis, capillary wicking is maintained over &gt;10 years after plasma functionalization of a scaffold material used for biomedical engineering. Electrospun membranes of poly(ε‐caprolactone) are coated with an oxygen‐functional hydrocarbon layer, deposited in a competitive ablation and plasma polymerization process with CO 2 and C 2 H 4 as reactive gases. Chemical analysis immediately after coating, 9 months later, and after storing at ambient conditions for over 10 years, indicate a stable surface coating. Using defined geometries such as a cavity and an undercut, the underlying plasma interaction mechanisms are revealed, showing different synergies of energetic particles, depositing species with different surface reactivities, and oxidizing species. A concerted action of such species during plasma functionalization is key to enabling long‐term wetting properties. This has a major implication for the surface functionalization of scaffolds, textiles, membranes, or foams used in diverse fields. Surface modification ; Materials science ; Wetting ; Coating ; Chemical engineering ; Plasma polymerization ; Contact angle ; Plasma ; Oxidizing agent ; Plasma etching ; Nanotechnology ; Etching (microfabrication) ; Polymerization ; Layer (electronics) ; Composite material ; Organic chemistry ; Chemistry ; Polymer Electrospun Nanofibers in Biomedical Applications ; Graphene and Nanomaterials Applications ; Surface Modification and Superhydrophobicity
Authors: Yolimar Gil | María Mar Quesada‐Moreno | María A. Palacios | Silvia Gómez‐Coca | Enrique Colacio | Eliseo Ruíz | Daniel Aravena
Source: Inorganic Chemistry Frontiers (article, 2025-01-01)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Determining the zero-field cooling/field cooling blocking temperature from AC susceptibility data for single-molecule magnets This article presents a model to determine the ZFC/FC blocking temperature from AC susceptibility and magnetization decay data. The accuracy of the proposal was verified for a new D 5h Dy III complex and a large dataset of published systems. Magnet ; Field (mathematics) ; Materials science ; Blocking (statistics) ; Zero temperature ; Condensed matter physics ; Thermodynamics ; Physics ; Computer science ; Quantum mechanics Magnetic Properties of Alloys ; Advanced NMR Techniques and Applications ; Quantum and electron transport phenomena