jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Valeria Olmedo Galarza | Nicolás Sebastián Pinto-Mosquera | Holguer Marcelo Pineda-Flores | Luis Armando Manosalvas-Quiroz
Source: Sustainability (article, 2025-12-05)
Field: Materials Science — Biomaterials

Citrus Waste Valorization: Unconventional Pathways for Sustainable Biomaterials and Bioactive Products Citrus fruits are among the most important global crops, with annual production exceeding 160 million tons. Processing produces significant waste, mainly peels, seeds, and pulp, which can make up to fifty percent of the fruit’s mass. This review critically examines innovative ways to valorize these byproducts. Recent research shows that peels, seeds, and pulp can be converted into high-value materials, including biocomposites and biomaterials, marking a shift from traditional uses like animal feed and biogas production. Notable innovations include smart packaging, pectin-based wound dressings, and biodegradable polymers for sustainable electronics. Advanced green extraction methods, such as deep eutectic solvents, have achieved extraction yields over 85% for flavonoids. Additionally, multifunctional biorefineries processing citrus and olive residues have increased biogas yields by 38–42%. The review explores emerging applications in nanotechnology, nutraceuticals, biodegradable polymers, and functional coatings, all aligned with principles of circular economy and green chemistry. These advances suggest that citrus waste can play a significant role in sustainability efforts and new market development. The review also discusses barriers to adoption, including scalability challenges, regulatory limits, and consumer acceptance, from both global and regional viewpoints. Biogas ; Circular economy ; Sustainability ; Biogas production ; Pulp (tooth) ; Biofuel ; Renewable energy ; Extraction (chemistry) Nanocomposite Films for Food Packaging ; Advanced Cellulose Research Studies ; Natural Fiber Reinforced Composites
Authors: Alfonso Cruz | Zhiyang Jin | Lukas Graber
Source: Applied Sciences (article, 2025-09-12)
Field: Materials Science — Materials Chemistry

Supercritical Fluids as Alternative Insulation and Arc-Quenching Medium This paper reviews the historical progression of arc-quenching media and examines the unique properties of supercritical carbon dioxide (scCO2), including its transport characteristics, electrical breakdown resilience, and structural behavior. Through analysis of ionization mechanisms, mean free path, and heat dissipation, scCO2 emerges as a viable insulating and arc-quenching medium, offering competitive performance and reduced environmental impact. Projected performance metrics for arcing time and dielectric strength show scCO2’s competitive edge. The limitations of alternative supercritical fluids and the potential benefits of scCO2 mixtures are discussed. In addition, the paper highlights the development of the first 72 kV scCO2 AC circuit breaker, marking a significant step toward sustainable high-voltage applications. This work positions scCO2 as a viable, environmentally friendly alternative to SF6, with promising implications for future power systems. Supercritical fluid ; Supercritical carbon dioxide ; Environmentally friendly ; Work (physics) ; Dielectric ; Dielectric strength High voltage insulation and dielectric phenomena ; Power Transformer Diagnostics and Insulation ; Vacuum and Plasma Arcs
Authors: Gréta Törős | Hassan El-Ramady | Neama Abdalla | Tamer Elsakhawy | József Prokisch
Source: International Journal of Molecular Sciences (review, 2025-11-09)
Field: Materials Science — Biomaterials

Valorization of Mushroom Residues for Functional Food Packaging The mushroom industry generates a substantial amount of residues each year, encompassing materials such as processing residues and spent substrates. Much of this biomass is discarded, despite its richness in valuable compounds. Mushroom residues contain bioactive substances including β-glucans, phenolic compounds, proteins, and dietary fiber, all of which are well known for their antioxidant and antimicrobial properties. While fruit and vegetable residues have been extensively explored as raw materials for eco-friendly packaging, mushroom-derived residues remain a largely underutilized resource. Recent studies have highlighted their potential as a renewable source of functional ingredients for sustainable food packaging. By applying green extraction technologies such as ultrasound- or microwave-assisted methods, researchers can recover stable bioactive compounds and incorporate them into biodegradable polymers. Early results are promising: packaging films enriched with mushroom residue extracts demonstrate improved mechanical strength, enhanced barrier properties, and added bioactivity. This strategy aligns with the principles of the Circular Economy, simultaneously reducing environmental impact and adding value to materials that were previously discarded. Although further optimization is needed, particularly regarding extraction efficiency, compound stability, and scalability, the valorization of mushroom residues represents a promising pathway toward the next generation of sustainable, eco-friendly packaging materials. Mushroom ; Raw material ; Functional food ; Residue (chemistry) ; Food products ; Active packaging ; Edible mushroom ; Food industry Nanocomposite Films for Food Packaging ; Polysaccharides and Plant Cell Walls ; Postharvest Quality and Shelf Life Management
Authors: Maria L. B. Pertence | Marina V. Guedes | Rosimeire C. Barcelos | Jerônimo Marteleto Nunes Rugani | Rodrigo Pedro Soares | Jean Lucas Bezerra da Cruz | Alessandra Mara de Sousa | Rubens Lima do Monte‐Neto | L. S. Gomes | Anna Carolina Pinheiro Lage | Ubirajara Agero
Source: Nanomaterials (article, 2025-09-05)
Field: Materials Science — Materials Chemistry

Investigation of Viscoelastic Properties of Macrophage Membrane–Cytoskeleton Induced by Gold Nanorods in Leishmania Infection Cell membranes and the cytoskeleton play crucial roles in the regulation of cellular responses by mediating mechanical forces and physical stimuli from the microenvironment through their viscoelastic properties. Investigating these properties provides valuable insights into disease mechanisms and therapeutic strategies. Gold nanorods (GNRs), especially under irradiation, exhibit lethal effects against <i>Leishmania</i> parasites through plasmonic photothermal conversion. In this study, we focus on evaluating the effects of non-irradiated GNRs on macrophage properties to better understand their intrinsic interactions with cells and support the development of future phototherapy applications. Here, defocusing microscopy (DM), a quantitative phase microscopy technique, was used to analyze membrane fluctuations in macrophages (M&empty;s) exposed to GNRs (average length of 43±8 nm and diameter of 20±4 nm) and infected with <i>Leishmania amazonensis</i>. By quantifying membrane-cytoskeleton fluctuation from defocused images, we extracted viscoelastic parameters, including bending modulus (kc) and viscosity (η), to characterize membrane behavior in detail. Our results show that infection increases both kc and η, while treatment at IC<sub>50</sub> reduces infection and selectively increases kc without affecting η. In healthy macrophages, exposure to GNRs resulted in a reduction in both parameters, indicative of increased membrane fluidity and cytoskeletal rearrangement. These findings provide new insights into the biomechanical effects of GNRs on macrophages and may enlighten the design of future phototherapeutic approaches. Nanorod ; Viscoelasticity ; Macrophage ; Cytoskeleton ; Materials science ; Leishmania ; Biophysics ; Nanotechnology ; Composite material ; Chemistry ; In vitro ; Biology ; Cell ; Biochemistry Nanoparticles: synthesis and applications ; Gold and Silver Nanoparticles Synthesis and Applications ; Nanoparticle-Based Drug Delivery
Authors: Veronika Svačinová | Tomáš Pluháček | Martin Petr | Karolı́na Šišková
Source: Royal Society Open Science (article, 2025-01-01)
Field: Materials Science — Materials Chemistry

Maturing conditions of bimetallic nanocomposites as a new factor influencing Au–Ag synergism and impact of Cu(II) and/or Fe(III) on luminescence Gold-silver synergism has been well documented in many scientific works dealing with luminescent nanostructures that are exploitable in biomedical and environmental application. Frequently, the ratio of Au : Ag in synthetic mixtures was varied to influence the extent of Au-Ag synergism of the resulting luminescent gold-silver nanoclusters (GSNCs). However, in our approach, a new step, maturing under differing conditions using the same Au : Ag ratio (5 : 1), has been investigated systematically for the very first time. As referent systems, monometallic gold nanoclusters (AuNCs) and protein treated by the conditions of synthesis and maturing were prepared and investigated. The selected types of maturing conditions led to distinct changes in fluorescence characteristics and, consequently, Au-Ag synergism extent (evaluated as the ratio of fluorescence quantum yields of GSNCs versus AuNCs). The best synergism was obtained for GSNCs matured at 37°C for 2.5 h. The stability of luminescent signal of these GSNCs was tested in the presence of an excess (to 20 mM) of Cu(II) and/or Fe(III) ions (crucial cofactors in living systems). The same metallic ion concentration caused different extents of GSNC luminescence quenching, for which a plausible reasoning is suggested. Nanoclusters ; Luminescence ; Bimetallic strip ; Metal ; Fluorescence ; Quenching (fluorescence) ; Nanocomposite ; Materials science ; Metal ions in aqueous solution ; Photochemistry ; Nanotechnology ; Chemistry ; Chemical engineering ; Metallurgy ; Optoelectronics ; Physics Nanocluster Synthesis and Applications ; Advanced Nanomaterials in Catalysis ; Gold and Silver Nanoparticles Synthesis and Applications
Authors: Fabienne Bachtiger | Aliff Rahimee | Lunna Li | Matteo Salvalaglio
Source: Industrial & Engineering Chemistry Research (article, 2025-01-07)
Field: Chemistry — Physical and Theoretical Chemistry

Solution Thermodynamics of <scp>l</scp> -Glutamic Acid Polymorphs from Finite-Sized Molecular Dynamics Simulations Efficiently obtaining atomic-scale thermodynamic parameters characterizing crystallization from solution is key to developing the modeling strategies needed in the quest for digital design strategies for industrial crystallization processes. Based on the thermodynamics of crystal nucleation in confined solutions, we develop a simulation framework to efficiently estimate the solubility and surface tension of organic crystals in solution from a few unbiased molecular dynamics simulations at a reference temperature. We then show that such a result can be extended with minimal computational overhead to capture the solubility curve. This enables an efficient and self-consistent estimate of the solubility and limit of solution stability associated with crystal nucleation in molecular systems from equilibrium molecular dynamics without the need for sophisticated free energy calculations. We apply our analysis to investigate the relative thermodynamic stability and aqueous solubility of the α and β polymorphs of l-glutamic acid. Our analysis enables an efficient appraisal of emergent ensemble properties associated with the thermodynamics of nucleation from solutions against experimental data, demonstrating that while the absolute solubility is still far from being quantitatively captured by an off-the-shelf point charge transferable force field, the relative polymorphic stability and solubility obtained from finite temperature simulation are consistent with the experimentally available information on glutamic acid. We foresee the ability to efficiently obtain solubility information from a limited number of computational experiments as a critical component of high-throughput polymorph screenings. Molecular dynamics ; Thermodynamics ; Chemistry ; Physics ; Physical chemistry ; Computational chemistry thermodynamics and calorimetric analyses ; Crystallization and Solubility Studies ; Protein Structure and Dynamics
Authors: Teng Ma | Xiaokun Geng | Weiwei Shi | Chunli Yu | Xue-Song Wu | Nannan Cui | Ze Qiang Zhao | Huazhong Li | Chuanliang Zhao | Qingbin Ni | Xiaodan Zhu | Pengcheng Xia
Source: Frontiers in Bioengineering and Biotechnology (article, 2025-09-03)
Field: Materials Science — Biomaterials

γ-Oryzanol-Loaded PLGA nanoparticles: enhanced drug delivery and therapeutic efficacy for breast cancer therapy Collectively, these findings demonstrate that γ-oryzanol@PLGA NPs significantly improve drug delivery efficiency and therapeutic potency while maintaining excellent biocompatibility. This presents a promising nanoplatform for breast cancer treatment, warranting further preclinical development. Future studies should focus on <i>in vivo</i> validation and the exploration of combination therapies to fully realize the potential of this novel approach. PLGA ; Drug delivery ; Breast cancer ; Drug ; Medicine ; Cancer therapy ; Pharmacology ; Nanoparticle ; Cancer ; Nanotechnology ; Materials science ; Internal medicine Nanoparticle-Based Drug Delivery ; Graphene and Nanomaterials Applications ; Advanced Drug Delivery Systems
Authors: Milica Lučić | Antonije Onjia
Source: Processes (article, 2025-11-13)
Field: Chemistry — Analytical Chemistry

Ultrasound-Assisted Microextraction for Food Chemical Contaminant Analysis: A Review Ultrasound-assisted microextraction (UAME) has emerged as a powerful and sustainable technique for food chemical contaminant analysis, offering a rapid, efficient, and environmentally friendly alternative to conventional extraction methods. This review provides a comprehensive overview of recent advancements in the application of UAME for the determination of various food chemical contaminants, including pesticide residues, potentially toxic elements, mycotoxins, veterinary drugs, and other chemical contaminants. The fundamental principles of ultrasound-assisted extraction are discussed, with an emphasis on the mechanisms of acoustic cavitation and mass transfer enhancement that enable improved analyte recovery from complex food matrices. Key factors influencing extraction efficiency (solvent selection, ultrasonic frequency and power, extraction time, and sample characteristics) were critically analyzed. Additionally, the integration of UAME with modern analytical platforms, such as LC-MS, GC-MS, and ICP-MS, was explored, highlighting its compatibility with high-throughput and multiresidue detection. Compared with traditional techniques, UAME offers significant benefits, including reduced solvent consumption, shorter extraction times, and improved analytical performance. This review also addresses current limitations and future perspectives, particularly regarding standardization, automation, and application in routine food safety monitoring. Overall, UAME represents a promising direction for more sustainable and efficient food chemical contaminant analysis, aligning with the growing demand for green analytical chemistry approaches. Extraction (chemistry) ; Analyte ; Sample preparation ; Solvent extraction ; Chemical sensor ; Environmentally friendly ; Food safety ; Food processing Analytical chemistry methods development ; Pesticide Residue Analysis and Safety ; Melamine detection and toxicity
Authors: Paulina Trzaskowska | Ewa Rybak | Kamil Kopeć | Tomasz Ciach | Piotr Wieciński | Wojciech Święszkowski | Ewa Kijeńska‐Gawrońska
Source: Frontiers in Bioengineering and Biotechnology (article, 2025-12-03)
Field: Materials Science — Biomaterials

Electrospun bioactive polymer biomaterials enriched with collagen and platelet-rich plasma as a platform for in vitro chondrogenic differentiation of human mesenchymal stem cells Furthermore, the observations revealed the presence of two critical markers of cartilage differentiation: namely, actin cytoskeletal reorganization and depolymerization. The presented findings highlight the potential of bioactive PLA fibrous mats enriched with PRP and collagen I as promising platforms for cartilage tissue regeneration. The combination of electrospinning techniques enables tailored fiber structures that support chondrogenesis, offering a potential alternative for tissue engineering applications. Chondrogenesis ; Mesenchymal stem cell ; Electrospinning ; In vitro ; Tissue engineering ; Cartilage ; Cytoskeleton Electrospun Nanofibers in Biomedical Applications ; Periodontal Regeneration and Treatments ; Silk-based biomaterials and applications
Authors: Carina Emminger | Umut Çakmak | Nikonov Anatolji | Michael Lackner | Zoltán Major
Source: Journal of Materials Research and Technology (article, 2025-08-27)
Field: Materials Science — Polymers and Plastics

Advanced characterization of the damping dynamics of silicone elastomers and natural rubber using the instrumented rebound resilience tester This study investigates the relationship between rebound resilience (RR) and damping dynamics in elastomers using an instrumented pendulum impact tester. Four materials, three silicone elastomers and one natural rubber (NR), with varying Shore hardnesses from 00 to 10 to A50 were examined. The materials were chosen to compare silicone elastomers, specifically poly(dimethylsiloxane) (PDMS), at different hardness levels to standard NR, known for its good vibration damping, high tensile strength, and economic advantages but limited durability under severe environmental conditions. PDMS, conversely, offers superior weatherability and broader temperature applicability. Traditional RR pendulum impact testing yields only discrete resilience values and inadequately describes damping dynamics. Thus, the RR tester was instrumented with a high-speed camera and piezoelectric force sensor to capture detailed impact forces and dissipation energies, providing comprehensive insights into rebound dynamics. Three distinct phases of pendulum motion were analyzed: initial deflection α initial at time t initial , impact α impact at t impact , and maximum rebound height α rebound at t rebound . Results confirm that RR inversely correlates with mechanical damping; however, elastomers with similar RR values displayed significantly different force profiles due to distinct damping dynamics. The results reveal that the softest silicone (Ecoflex 00–10) and NR exhibited similar RR (∼0.33) but significant different impact forces (85 N vs. 656 N). Impact duration and force were influenced by hardness and macroscopic deformation under impact. These findings challenge the traditional hardness-damping relationship and provide a framework for elastomer characterization in dynamic applications. Materials science ; Resilience (materials science) ; Elastomer ; Characterization (materials science) ; Silicone rubber ; Composite material ; Natural rubber ; Silicone ; Natural frequency ; Polymer science ; Forensic engineering ; Vibration ; Nanotechnology ; Acoustics ; Engineering Polymer crystallization and properties ; Polymer Nanocomposites and Properties ; Mechanical Engineering and Vibrations Research
Authors: Ivana Figueiredo de Oliveira Aquino | Franscristhiany Silva Souza | Juan Magalhães Paiva | Takanori Yoshikawa | Hilton Costa Louzeiro | Mikele Cândida Sousa de Sant’Anna | Gabriel Francisco da Silva
Source: OBSERVATÓRIO DE LA ECONOMÍA LATINOAMERICANA (article, 2025-07-10)
Field: Materials Science — Biomaterials

Biomedical potential and applications of fish collagen: an integrative literature review In view of the growing demand for sustainable and safe biomaterials, this integrative review study aims to investigate the biomedical applications of fish-derived collagen by analyzing studies published between 2019 and 2024. The PubMed and Web of Science databases were searched using descriptors from DeCS/MeSH (Fish, Collagen, Potential Biomedical, and Applications). The Research Rabbits tool was also used to assist in the selection of relevant journals. After rigorous application of inclusion and exclusion criteria, 9 studies were selected. The studies indicate that fish collagen has promising potential with therapeutic advantages over traditional collagens, such as lower risk of contamination and allergic reactions, including wound healing, tissue regeneration, fabrication of hydrogels and collagen sponges for applications in biomedical devices. However, challenges remain related to the standardization of extraction methods and variability between fish species. It is concluded that, with the improvement of techniques and the overcoming of regulatory obstacles, the biomaterial can consolidate itself as a sustainable alternative for regenerative medicine and tissue engineering. Fish <Actinopterygii> ; Fishery ; Biology Collagen: Extraction and Characterization
Authors: Štěpánka Bílá | Dominik Pinkas | Krishna Khakurel | J. Boger | Tomáš Bílý | János Hajdu | Zdeněk Franta | Roman Tůma | L. Redecke | Vitaly Polovinkin
Source: bioRxiv (Cold Spring Harbor Laboratory) (preprint, 2025-07-11)
Field: Materials Science — Materials Chemistry

<i>In situ</i> protein crystallography: a single-crystal electron diffraction pipeline for structure determination inside living cells Abstract Intracellular crystallization is an emerging approach in structural biology that bypasses the need for protein purification. An InCellCryst pipeline was recently established for structure determination by serial X-ray crystallography. Serial crystallography requires the exposure of tens of thousands of cells containing intracellular crystals, precluding high-resolution structural studies on proteins with low numbers of crystals. To overcome this limitation, we combined the InCellCryst approach with the advantages of 3D electron diffraction and established the new IncellED method. Using microcrystals of the HEX-1 protein from Magnaporthe grisea , grown inside High Five insect cells, we demonstrate that electron diffraction data collected from a single crystal yields a high-resolution structure at 1.9 Å resolution, comparable to 1.8 Å achieved by serial X-ray crystallography. The IncellED methodology opens structure determination for proteins that crystallize with low efficiency and use widely available electron cryo-microscope infrastructure, paving the way for intracellular macromolecular electron crystallography at high resolution. In situ ; Electron crystallography ; Crystallography ; Diffraction ; Pipeline (software) ; Electron diffraction ; Materials science ; Protein crystallization ; Crystal structure ; X-ray crystallography ; Chemistry ; Optics ; Physics ; Engineering ; Crystallization ; Mechanical engineering Enzyme Structure and Function