jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Rohini Armo | Saroj Kumar Sah | J. Sangeetha | Namrata Shailesh Khadake | Akash Chauhan | T. Nandhini Devi | Damodar Goundar | Mohd Wasiullah
Source: Journal of Carcinogenesis (article, 2025-01-01)
Field: Chemistry — Analytical Chemistry

RP-HPLC Method Development and Validation for Quality Control and Forced Degradation Analysis of Paracetamol–Ibuprofen Multi-Component Formulations This study presents the development and validation of a robust reverse-phase high-performance liquid chromatography method for the simultaneous estimation of paracetamol and ibuprofen in multi-component pharmaceutical formulations. Paracetamol and ibuprofen are widely prescribed analgesic and antipyretic agents, frequently co-formulated to enhance therapeutic efficacy. Analytical challenges arise due to overlapping absorbance spectra, distinct physicochemical properties, and susceptibility to degradation under stress conditions. To address these challenges, an isocratic reverse-phase high-performance liquid chromatography method was optimized using a mobile phase of acetonitrile and phosphate buffer (pH 3.0) in a 60:40 v/v ratio, with detection carried out on a PDA detector at 220–230 nm. Method validation was performed in accordance with ICH Q2(R1) guidelines, evaluating parameters such as linearity, accuracy, precision, specificity, robustness, and sensitivity. The method demonstrated excellent resolution, with paracetamol and ibuprofen eluting at approximately 2.5 and 5.2 minutes, respectively. Forced degradation studies confirmed the stability-indicating capacity, with paracetamol showing higher degradation under acidic conditions and ibuprofen under oxidative stress. Linearity was established in the range of 10–100 µg/mL for both drugs, with correlation coefficients exceeding 0.999. The limits of detection and quantitation were sufficiently low, confirming suitability for trace analysis. Robustness testing indicated consistent performance under minor variations in flow rate, pH, and detection wavelength. Overall, the method proved to be accurate, precise, and stability-indicating, making it suitable for routine quality control, regulatory submissions, and stability testing of fixed-dose paracetamol–ibuprofen formulations. This validated reverse-phase high-performance liquid chromatography technique offers a reliable analytical framework that can be extended to other multi-component pharmaceutical preparations. Forced degradation ; Ibuprofen ; Degradation (telecommunications) ; Robustness (evolution) ; Phosphate buffered saline ; Absorbance ; Quality by Design ; Acetonitrile Analytical Methods in Pharmaceuticals ; Analytical Chemistry and Chromatography ; Nonlinear Optical Materials Research
Authors: Vishal Prajapati | Deepak Panchal | Madhu Dikshit | Rajesh Patel | Sunil Bhavsar | Ashish Patel | Dipak Kumar Sahoo | Kuldeep Luhana
Source: Frontiers in Microbiology (article, 2025-10-30)
Field: Materials Science — Materials Chemistry

Green synthesis of silver nanoparticles by Kocuria flava isolated from photovoltaic panels for combating infections, cancer, and water pollution The extremophilic bacterial community associated with photovoltaic solar panels has demonstrated significant resilience to harsh environmental conditions such as desiccation, thermal fluctuations, and intense solar exposure. The bacterial strain <i>Kocuria flava</i> KKYHNGU1 was isolated from a PV panel and characterized for its resistance to alkaline pH (pH 9), salinity (1-9% w/v), UV radiation (approximately 8 min), and high temperatures (up to 55 °C). Bio-manufactured AgNPs from this isolate were characterized, including UV-visible spectroscopy (with wavelength peaks at 437 nm), FTIR, and X-ray diffraction, validating the crystalline configuration of the AgNPs, exhibiting intensity peaks at 28.02°, 32.46°, and 46.36°. The spherical shape and size (96 nm diameter) along with the silver content (87.06% w/w) of bio-synthesized AgNPs was confirmed through scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy. Metabolomic analysis through LC-MS revealed the presence of bioactive compounds possessing significant antimicrobial and anti-cancer properties, in addition to marked reduction capabilities. They have manifested notable antibacterial potential against <i>Staphylococcus aureus</i> with a 14 mm zone of inhibition and also proved effectiveness against <i>Serratia marcescens</i>, <i>Bacillus cereus</i>, and <i>Escherichia coli</i>. Additionally, the AgNPs effectively removed trimethoprim, achieving a 63.42% removal at 10 ppm within 120 min. These bio-fabricated AgNPs displayed remarkable anti-proliferative and pro-apoptotic activity against the THP-1 monocytic leukemia cell line, yielding an IC50 measurement of 40 μg/mL. These findings underscore the prospective applications of biogenic AgNPs in wastewater treatment and biomedical fields, illustrating their multiple functionalities. Silver nanoparticle ; Photovoltaic system ; Scanning electron microscope ; Biofouling ; Pollutant ; Antibacterial activity ; Antimicrobial ; Nanoparticle ; Environmental pollution Nanoparticles: synthesis and applications ; Cancer Research and Treatments ; Graphene and Nanomaterials Applications
Authors: H. Belkhodja | A. Remil | F.Z. Labbaci | F. Belkhadem | D. Bouhadi | Z. Benattouche
Source: Grasas y Aceites (article, 2025-06-30)
Field: Chemistry — Organic Chemistry

Physicochemical and spectroscopic characterization, and evaluation of the antioxidant and anti-inflammatory potential of oils extracted from Thunnus thynnus and Sardina pilchardus coproducts This work aims to valorize the coproducts of two pelagic species, bluefin tuna (Thunnus thynnus) and sardines (Sardina pilchardus), by the extraction and characterization of the oil coproducts through physicochemical and FTIR-ATR analysis and the in vitro evaluation of their antioxidant and anti-inflammatory potential. Determining the physicochemical parameters revealed that both oils tested are of good quality. The UV-visible absorption spectra presented a strong absorbance band at 310 nm. Therefore, oil from S. pilchardus and T. thynnus may predominate ω-3 and 9 in its spectrum. The FTIR-ATR spectrum showed bands and peaks corresponding to functional groups of the substances tested. Evaluation of the antioxidant and anti-inflammatory potential showed that the oil from S. pilchardus coproducts showed the highest reduction percentage and even the highest anti-inflammatory potential compared to T. thynnus. Coproduct oil offers significant therapeutic value as a substitute substance or therapeutic support for reducing oxidative stress and inflammation. Antioxidant ; Coproduct ; Tuna ; Thunnus ; Extraction (chemistry) Edible Oils Quality and Analysis ; Essential Oils and Antimicrobial Activity ; Medicinal Plant Research
Authors: В.И. Теличенко | V. I. Rimshin | Ekaterina Ketsko
Source: International Journal for Computational Civil and Structural Engineering (article, 2025-12-26)
Field: Materials Science — Materials Chemistry

TITLE EMERGENCY CALCULATION OF THE INDUSTRIAL BUILDING STRUCTURE Emergency situations calculation for the industrial buildings structures is an important element in ensuring their reliability and safety in conditions that contribute to the emergence of significant social, environmental and economic consequences. This calculation is mandatory for objects of a high responsibility level (class KS-3), and can be carried out on a voluntary basis for objects of class KS-2, where a large number of people are expected to be present. The article presents the calculation of the industrial building structures with a high responsibility level and analyzes its results. The calculation was performed in accordance with paragraph 5.1 in SP 56.13330.2011 «Industrial buildings» for resistance to progressive collapse as an emergency situation result. A secondary model was created based on the primary calculation model. An emergency failure case of the middle load-bearing column in the frame along the 18/H axis was selected having analyzed the space-planning and design solutions for this building. It was established that the required beams and the roof slab reinforcement obtained as a calculation result of the secondary model does not exceed that obtained as a primary model calculation result based on the calculations performed results. Also, based on the calculation results of the ozone-sorption block building secondary model (fast filter section) for an emergency situation, it was determined that when such a situation occurs - when one of the columns is turned off - the remaining load-bearing elements take on additional forces without losing strength and stability, that is, resistance to the structure progressive collapse will be ensured. Roof ; Column (typography) ; Progressive collapse ; Frame (networking) ; Paragraph ; Block (permutation group theory) ; Slab ; Reliability (semiconductor) ; Reinforced concrete Structural mechanics and materials ; Structural Response to Dynamic Loads ; Environmental and Industrial Safety
Authors: Antonio Formisano | Dario De Fazio | A. Langella | Martina Panico | Massimo Durante
Source: The International Journal of Advanced Manufacturing Technology (article, 2025-12-17)
Field: Materials Science — Polymers and Plastics

Comparison between cold incremental and stretch forming of flax fiber-reinforced polypropylene composites Abstract Incremental sheet forming, born as a versatile and cost-effective alternative to traditional procedures to deform incrementally and without dedicated dies flat metal sheets into complex three-dimensional shapes, has recently been gaining attention as a forming technique for polymers and composites. Among these, natural fiber-reinforced thermoplastics have been climbing in popularity because natural fibers are widely available, act as effective polymer reinforcement, and make the composite semi-biodegradable. Through compression molding and using natural woven fabrics, it is also possible to achieve good fiber/matrix coupling without compromising the environmental benefits with chemical coupling agents and/or treatments. This experimental study compares cold incremental and stretch forming processes of flax woven fabric-reinforced polypropylene composites for the manufacture of spherical caps. By considering formability, geometrical accuracy, forming forces, power, and energy consumption, the study highlights the effectiveness of incremental forming applied to these biobased composites, without resorting to full counter dies and heating stages, to manufacture components with increased mechanical performance. Polypropylene ; Composite number ; Molding (decorative) ; Cold forming ; Coupling (piping) ; Compression molding ; Polymer ; Sheet moulding compound Natural Fiber Reinforced Composites ; Mechanical Behavior of Composites ; Advanced Materials and Mechanics
Authors: Juan D. de la Cruz-Barrios | Paulina Abrica-González | Sinai G. Gutiérrez-Cruz | Alejandro Muñoz-Diosdado | Jorge A. Mendoza-Pérez | Alain Sánchez-González
Source: Frontiers in Nanotechnology (article, 2025-11-17)
Field: Materials Science — Materials Chemistry

Evaluation of the genotoxicity of gold nanoparticles by single-cell electrophoresis The distinctive characteristics and wide-ranging applications of gold nanoparticles (AuNPs) have sparked considerable scientific interest, leading to increased use and a rise in publications and patents. However, their environmental and genotoxic impact remains poorly understood. In this study, we evaluated the genotoxicity and mutagenicity of AuNPs in germinated roots of Vicia faba using three approaches: a comet assay to detect DNA damage, mitotic index analysis, and assessment of chromosomal abnormalities. We observed a reduced mitotic index, increased chromosomal abnormalities, and significant DNA damage in treated samples, indicating genetic alterations and a potential environmental risk. These findings underscore the significance of evaluating the biological effects of AuNPs and demonstrate that single-cell electrophoresis is a reliable tool for assessing genetic damage in plants. Genotoxicity ; Comet assay ; Colloidal gold ; DNA damage ; Gel electrophoresis ; Mitotic index ; DNA Nanoparticles: synthesis and applications ; Plant Genetic and Mutation Studies ; Plant tissue culture and regeneration
Authors: Puntaree Taeprayoon | Tanagon Junhamakasit
Source: ASEAN Journal of Scientific and Technological Reports (article, 2025-07-05)
Field: Materials Science — Biomaterials

Development of Biodegradable Cat Litter from Water Hyacinth This study focused on the technical feasibility and optimization of formulation performance characteristics to explore the potential of water hyacinth (Eichhornia crassipes) for biodegradable cat litter development. Five water hyacinth-based formulations (T1-T5) were developed and compared with commercial tofu-based cat litter (T6). Formulation T5 exhibited the highest water absorption capacity (64.23 ± 2.31%) compared to T6, the commercial product (47.42 ± 1.00%). T5 contained water hyacinth (61.7 g) and carboxymethyl cellulose (35 g), creating an optimal synergy for moisture retention. Water hyacinth formulations demonstrated superior structural integrity under impact testing, with T2-T5 showing zero breakage when dropped from heights up to 3 m, compared to T6's 2.10% fragmentation rate. Commercial litter dried faster (0.21 g/m²/s) than water hyacinth formulations (0.11-0.17 g/m²/s), presenting an area for optimization. The research demonstrates the viability of water hyacinth as an eco-friendly cat litter material, effectively converting an invasive aquatic plant into a value-added product with absorption capacity and durability advantages over commercial alternatives, while supporting environmental sustainability through the beneficial repurposing of problematic biomass. Hyacinth ; Litter ; Moisture ; Absorption of water ; Eichhornia crassipes ; Aquatic plant ; Sustainability biodegradable polymer synthesis and properties ; Sustainability and Innovation in Business ; Materials Engineering and Processing
Authors: Piyush Ojha | Seema Acharya
Source: Indian Journal of Science and Technology (article, 2025-10-21)
Field: Materials Science — Materials Chemistry

Solubilization of 5- Amino Salicylic Acid in Different Micellar Media: A Fluorescence Approach Objective: To develop solubilization of 5- amino salicylic acid in different micellar media for Pharmaceuticals, biological sciences, detergency, beauty products, manufacturing of textiles, engineering. Methods: A fluorescence approach with anionic, cationic, and nonionic micellar media were used to study the solubilization of 5-amino salicylic acid (5-ASA) at varying concentrations. Absorption spectrum measurements have also verified the solubilization phenomena. In micellar mediums with varying compound concentrations, spectral characteristics such as quantum yield, Stokes' shift, and molar extinction coefficient were computed. Findings: Changes in the solubilization pattern in the presence of various surfactant classes have been demonstrated by changes in the curve area and quantum yield. Novelty: Catalytic solvents have had the greatest impact on the solubilization of 5-amino salicylic acid in its aqueous solution. This study involved in solubilization of 5- amino salicylic acid in different micellar media surfactant-based separations, chemical analysis, emulsion, polymerisation, micellar catalysis, and environmental processes are just a new of the fields that have used solubilization. Keywords: 5- Amino Salicylic acid (5-ASA), Solubilization, Micellar media, Spectral parameters, Quantum yield Salicylic acid ; Solubilization ; Fluorescence ; Micellar solutions ; Aqueous solution ; Pulmonary surfactant ; Absorption (acoustics) ; Molar absorptivity Crystallization and Solubility Studies ; Analytical Chemistry and Chromatography ; Surfactants and Colloidal Systems
Authors: Govind Gour | Antonio Pellegrino
Source: Journal of Alloys and Metallurgical Systems (article, 2025-12-06)
Field: Materials Science — Materials Chemistry

A comprehensive comparison of dynamic strain localisation and mechanical behaviour in traditional and additively manufactured Ti6Al4V Titanium alloys are widely used in aerospace, defence, automotive, and biomedical engineering owing to their high specific strength and excellent corrosion resistance. Additive manufacturing has emerged as a promising alternative to conventional production methods, offering the capability to fabricate complex geometries while reducing processing time and material waste. In this study, the high strain rate deformation behaviour of Ti6Al4V produced by selective laser melting is investigated using a Split Hopkinson Tension Bar system equipped with a multi-camera high-speed imaging setup. A comprehensive experimental programme is conducted on specimens manufactured in three different build orientations to assess the influence of processing direction on dynamic strain localisation and true stress–strain response. The post-necking behaviour is examined and compared with that of conventionally forged Ti6Al4V, revealing notable differences in ductility and strain localisation mechanisms. In addition, the high strain rate compressive behaviour of both material variants and their temperature dependence are investigated using a Split Hopkinson Compression Bar system equipped with thermal conditioning. The deformation and failure mechanisms of additively manufactured specimens produced in different orientations are further examined through post-mortem analysis of the fracture surfaces. • The dynamic behaviour and strain localisation of forged and SLM Ti6Al4V are compared. • The additive manufacturing process introduces significant anisotropy in the material. • A high-rate testing method incorporating dual high-speed imaging is presented. • The strain rate and temperature dependencies of both alloys are examined in detail. • The lower ductility of SLM Ti6Al4V must be considered in safety-critical component design. Split-Hopkinson pressure bar ; Ductility (Earth science) ; Titanium alloy ; Strain rate ; Deformation (meteorology) ; Compression (physics) ; Fracture (geology) ; Selective laser melting ; Tension (geology) High-Velocity Impact and Material Behavior ; Additive Manufacturing Materials and Processes ; Cellular and Composite Structures
Authors: Chanchila Kumari | Nupur Choudhary | Jyoti Sinha | AK Rai
Source: International Journal of Research in Agronomy (article, 2025-12-01)
Field: Materials Science — Biomaterials

Sustainable food preservation techniques for reducing postharvest losses and food waste Postharvest losses and food waste remain major challenges for global food security, economic stability, and environmental sustainability. Every year, a significant proportion of perishable foods such as fruits, vegetables, dairy, and meat are lost due to spoilage, inadequate storage, and inefficient handling, contributing to resource wastage and greenhouse gas emissions. Sustainable food preservation techniques offer effective solutions to mitigate these losses by extending shelf life, maintaining nutritional and sensory quality, and minimizing environmental impact. This review explores current and emerging preservation strategies, including novel thermal and non-thermal processing technologies, bioprocessing and fermentation approaches, and innovative packaging systems such as modified atmosphere, active, intelligent, and nanotechnology-based packaging. Emphasis is placed on the integration of these methods to achieve synergistic effects, reduce chemical additive usage, and promote sustainable postharvest management. Furthermore, challenges related to scalability, energy efficiency, regulatory compliance, and consumer acceptance are discussed, alongside future perspectives for the development of smart and sustainable food preservation systems. By combining technological innovation with sustainable practices, it is possible to reduce food waste, enhance food safety, and contribute to resilient and environmentally responsible food systems. Postharvest ; Food waste ; Food systems ; Sustainable agriculture ; Sustainability ; Bioprocess ; Food packaging ; Food processing ; Greenhouse gas Nanocomposite Films for Food Packaging ; Food Waste Reduction and Sustainability ; Food Drying and Modeling
Authors: Amorós Aparicio, Àngela | Peña, Javier
Source: Dipòsit Digital de Documents de la UAB (Universitat Autònoma de Barcelona) (article, 2025-01-01)
Field: Chemistry — Physical and Theoretical Chemistry

El lenguaje y la vida de los elementos químicos : inteligencia artificial y comunicación gráfica La inteligencia artificial, combinada con la comunicación gráfica, ofrece nuevas posibilidades para representar el lenguaje de los elementos químicos en la educación primaria. Esta aproximación visual y tecnológica no solo facilita la comprensión del universo químico, sino que potencia competencias STEM clave en edades tempranas. Equiparar los símbolos químicos al lenguaje alfanumérico mediante IA permite generar representaciones accesibles, creativas y significativas para los estudiantes, fomentando una alfabetización científica más temprana y contextualizada. Context (archaeology) ; Natural (archaeology) ; Subject (documents) ; The Imaginary History and advancements in chemistry ; Science Education and Pedagogy ; Technology in Education and Healthcare
Authors: Duc Huynh | Hang Nguyen | Tran Thien Dat Nguyen | Pham Thi Hong Nga | Pham Quan Anh | Thi Van Anh Duong | Van Huong Hoang | Xuan Tien Vo | Vinh Tien Nguyen
Source: Recent Progress in Materials (article, 2025-09-24)
Field: Materials Science — Polymers and Plastics

Effect of EVA on the Unnotched Impact Toughness of PP/HDPE/EVA Blends Beverage bottle caps are usually made from two primary materials: PP and HDPE. In this study, the evaluation criteria were the unnotched impact toughness and the microstructure of PP/HDPE/EVA samples produced by injection molding. The samples were tested according to ASTM D256. PP/HDPE/EVA blends were prepared with various ratios: 47.5/47.5/5, 45/45/10, 42.5/42.5/15, 40/40/20, and 37.5/37.5/25. The results showed that adding EVA to the PP/HDPE blend significantly increased the unnotched impact toughness: from 84.03 kJ/m&lt;sup&gt;2&lt;/sup&gt; (PP/HDPE/5% EVA) to 85.06 kJ/m&lt;sup&gt;2&lt;/sup&gt; (PP/HDPE/10% EVA), then decreased to 70.3 kJ/m&lt;sup&gt;2&lt;/sup&gt; (PP/HDPE/15% EVA), followed by an increase to 83.32 kJ/m&lt;sup&gt;2&lt;/sup&gt; (PP/HDPE/20% EVA) and 89.42 kJ/m&lt;sup&gt;2&lt;/sup&gt; (PP/HDPE/25% EVA). The discrepancy in value between the samples with the highest and lowest EVA content was 19.12 kJ/m&lt;sup&gt;2&lt;/sup&gt;. Overall, as the EVA content increased, the unnotched impact toughness also tended to increase. However, the sample with PP/HDPE/15% EVA showed a noticeable decrease. Toughness ; Microstructure ; Izod impact strength test ; Bottle ; Fracture toughness Polymer crystallization and properties ; Polymer Nanocomposites and Properties ; Polymer Nanocomposite Synthesis and Irradiation