jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Michael Wildy | Ping Lü
Source: Materials (review, 2023-11-07)
Field: Materials Science — Biomaterials

Electrospun Nanofibers: Shaping the Future of Controlled and Responsive Drug Delivery Electrospun nanofibers for drug delivery systems (DDS) introduce a revolutionary means of administering pharmaceuticals, holding promise for both improved drug efficacy and reduced side effects. These biopolymer nanofiber membranes, distinguished by their high surface area-to-volume ratio, biocompatibility, and biodegradability, are ideally suited for pharmaceutical and biomedical applications. One of their standout attributes is the capability to offer the controlled release of the active pharmaceutical ingredient (API), allowing custom-tailored release profiles to address specific diseases and administration routes. Moreover, stimuli-responsive electrospun DDS can adapt to conditions at the drug target, enhancing the precision and selectivity of drug delivery. Such localized API delivery paves the way for superior therapeutic efficiency while diminishing the risk of side effects and systemic toxicity. Electrospun nanofibers can foster better patient compliance and enhanced clinical outcomes by amplifying the therapeutic efficiency of routinely prescribed medications. This review delves into the design principles and techniques central to achieving controlled API release using electrospun membranes. The advanced drug release mechanisms of electrospun DDS highlighted in this review illustrate their versatility and potential to improve the efficacy of medical treatments. Drug delivery ; Biocompatibility ; Nanofiber ; Nanotechnology ; Drug ; Electrospinning ; Active ingredient ; Biocompatible material ; Materials science ; Biomedical engineering ; Pharmacology ; Medicine Electrospun Nanofibers in Biomedical Applications ; Advanced Sensor and Energy Harvesting Materials ; Polymer Nanocomposite Synthesis and Irradiation
Authors: Pavel A. Demakov
Source: Polymers (review, 2023-06-29)
Field: Chemistry — Inorganic Chemistry

Properties of Aliphatic Ligand-Based Metal–Organic Frameworks Ligands with a purely aliphatic backbone are receiving rising attention in the chemistry of coordination polymers and metal–organic frameworks. Such unique features inherent to the aliphatic bridges as increased conformational freedom, non-polarizable core, and low light absorption provide rare and valuable properties for their derived MOFs. Applications of such compounds in stimuli–responsive materials, gas, and vapor adsorbents with high and unusual selectivity, light-emitting, and optical materials have extensively emerged in recent years. These properties, as well as other specific features of aliphatic-based metal–organic frameworks are summarized and analyzed in this short critical review. Advanced characterization techniques, which have been applied in the reported works to obtain important data on the crystal and molecular structures, dynamics, and functionalities, are also reviewed within a general discussion. In total, 132 references are included. Metal-organic framework ; Polarizability ; Adsorption ; Materials science ; Ligand (biochemistry) ; Characterization (materials science) ; Polymer ; Metal ; Nanotechnology ; Selectivity ; Chemistry ; Organic chemistry ; Molecule ; Catalysis Metal-Organic Frameworks: Synthesis and Applications ; Magnetism in coordination complexes ; X-ray Diffraction in Crystallography
Authors: Furao Ren | Weijun Liu
Source: Catalysts (article, 2023-08-01)
Field: Chemistry — Inorganic Chemistry

Review of CO2 Adsorption Materials and Utilization Technology This article introduces the recent research status of CO2 adsorption materials and effective ways of CO2 resource utilization. Molecular sieves have the advantages of a large specific surface area, a wide pore size range, recyclability, and good chemical and thermal stability. Metal–organic frameworks have diverse structures and broad application prospects. The captured CO2 is converted into valuable chemicals such as acids, alcohols, hydrocarbons, and esters as raw materials. The rapid development of biomass energy utilization of CO2, with strong biological adaptability, high yield, low production cost, and low pollutant emissions, is a feasible method to reduce CO2 emissions. This article analyzes the current research status of CO2 capture, conversion into chemicals, biomass energy, and industrial utilization from the perspective of catalytic conversion. Raw material ; Biomass (ecology) ; Adaptability ; Environmental science ; Adsorption ; Waste management ; Biochemical engineering ; Process engineering ; Chemistry ; Engineering ; Organic chemistry Metal-Organic Frameworks: Synthesis and Applications ; Carbon Dioxide Capture Technologies ; Carbon dioxide utilization in catalysis
Authors: Xuanxiao Chen | Brian Josephson | Benjamin G. Davis
Source: ACS Central Science (review, 2023-03-21)
Field: Chemistry — Organic Chemistry

Carbon-Centered Radicals in Protein Manipulation Methods to directly post-translationally modify proteins are perhaps the most straightforward and operationally simple ways to create and study protein post-translational modifications (PTMs). However, precisely altering or constructing the C-C scaffolds pervasive throughout biology is difficult with common two-electron chemical approaches. Recently, there has been a surge of new methods that have utilized single electron/radical chemistry applied to site-specifically "edit" proteins that have started to create this potential-one that in principle could be near free-ranging. This review provides an overview of current methods that install such "edits", including those that generate function and/or PTMs, through radical C-C bond formation (as well as C-X bond formation via C• where illustrative). These exploit selectivity for either native residues, or preinstalled noncanonical protein side-chains with superior radical generating or accepting abilities. Particular focus will be on the radical generation approach (on-protein or off-protein, use of light and photocatalysts), judging the compatibility of conditions with proteins and cells, and novel chemical biology applications afforded by these methods. While there are still many technical hurdles, radical C-C bond formation on proteins is a promising and rapidly growing area in chemical biology with long-term potential for biological editing. Synthetic biology ; Chemical biology ; Radical ; Chemistry ; Posttranslational modification ; Nanotechnology ; Protein engineering ; Combinatorial chemistry ; Computer science ; Computational biology ; Biochemistry ; Materials science ; Biology Click Chemistry and Applications ; Biotin and Related Studies ; Chemical Synthesis and Analysis
Authors: John Peter Coats | Rémy Cochereau | Ionel Adrian Dinu | Daniel Messmer | Flavien Sciortino | Cornelia G. Palivan
Source: Macromolecular Bioscience (review, 2023-03-22)
Field: Chemistry — Organic Chemistry

Trends in the Synthesis of Polymer Nano‐ and Microscale Materials for Bio‐Related Applications Polymeric nano- and microscale materials bear significant potential in manifold applications related to biomedicine. This is owed not only to the large chemical diversity of the constituent polymers, but also to the various morphologies these materials can achieve, ranging from simple particles to intricate self-assembled structures. Modern synthetic polymer chemistry permits the tuning of many physicochemical parameters affecting the behavior of polymeric nano- and microscale materials in the biological context. In this Perspective, an overview of the synthetic principles underlying the modern preparation of these materials is provided, aiming to demonstrate how advances in and ingenious implementations of polymer chemistry fuel a range of applications, both present and prospective. Microscale chemistry ; Nanotechnology ; Context (archaeology) ; Polymer ; Materials science ; Nano- ; Polymer science ; Composite material Advanced Polymer Synthesis and Characterization ; Polymer Surface Interaction Studies ; Nanoparticle-Based Drug Delivery
Authors: Chenghua Deng | Li Zhao | Mei‐Yan Gao | Shaza Darwish | Bai‐Qiao Song | Debobroto Sensharma | Matteo Lusi | Yun‐Lei Peng | Soumya Mukherjee | Michael J. Zaworotko
Source: ACS Materials Letters (article, 2023-12-01)
Field: Chemistry — Inorganic Chemistry

Ultramicroporous Lonsdaleite Topology MOF with High Propane Uptake and Propane/Methane Selectivity for Propane Capture from Simulated Natural Gas Propane (C<sub>3</sub>H<sub>8</sub>) is a widely used fuel gas. Metal-organic framework (MOF) physisorbents that are C<sub>3</sub>H<sub>8</sub> selective offer the potential to significantly reduce the energy footprint for capturing C<sub>3</sub>H<sub>8</sub> from natural gas, where C<sub>3</sub>H<sub>8</sub> is typically present as a minor component. Here we report the C<sub>3</sub>H<sub>8</sub> recovery performance of a previously unreported lonsdaleite, <b>lon</b>, topology MOF, a chiral metal-organic material, [Ni(<i>S</i>-IEDC)(bipy)(SCN)]<sub>n</sub>, <b>CMOM-7</b>. <b>CMOM-7</b> was prepared from three low-cost precursors: Ni(SCN)<sub>2</sub>, <i>S</i>-indoline-2-carboxylic acid (<i>S</i>-IDECH), and 4,4'-bipyridine (bipy), and its structure was determined by single crystal X-ray crystallography. Pure gas adsorption isotherms revealed that <b>CMOM-7</b> exhibited high C<sub>3</sub>H<sub>8</sub> uptake (2.71 mmol g<sup>-1</sup>) at 0.05 bar, an indication of a higher affinity for C<sub>3</sub>H<sub>8</sub> than both C<sub>2</sub>H<sub>6</sub> and CH<sub>4</sub>. Dynamic column breakthrough experiments afforded high purity C<sub>3</sub>H<sub>8</sub> capture from a gas mixture comprising C<sub>3</sub>H<sub>8</sub>/C<sub>2</sub>H<sub>6</sub>/CH<sub>4</sub> (v/v/v = 5/10/85). Despite the dilute C<sub>3</sub>H<sub>8</sub> stream, <b>CMOM-7</b> registered a high dynamic uptake of C<sub>3</sub>H<sub>8</sub> and a breakthrough time difference between C<sub>3</sub>H<sub>8</sub> and C<sub>2</sub>H<sub>6</sub> of 79.5 min g<sup>-1</sup>, superior to those of previous MOF physisorbents studied under the same flow rate. Analysis of crystallographic data and Grand Canonical Monte Carlo simulations provides insight into the two C<sub>3</sub>H<sub>8</sub> binding sites in <b>CMOM-7</b>, both of which are driven by C-H···π and hydrogen bonding interactions. Propane ; Metal-organic framework ; Natural gas ; Methane ; Adsorption ; Topology (electrical circuits) ; Chemistry ; Hydrogen bond ; Single crystal ; Molecule ; Crystallography ; Physical chemistry ; Organic chemistry Metal-Organic Frameworks: Synthesis and Applications ; Zeolite Catalysis and Synthesis ; Inorganic Fluorides and Related Compounds
Authors: Matthias Otte
Source: European Journal of Organic Chemistry (article, 2023-03-03)
Field: Chemistry — Organic Chemistry

Reactions in Endohedral Functionalized Cages Abstract The introduction of enhanced functionalization is a key aspect in the current design of cage chemistry. At the moment, several approaches are intensively investigated. The synthesis of cage compounds that display endohedral functionalization plays a key role among them. Here, the studies of reactions that occur in endohedral‐functionalized cage compounds is reviewed. After an introduction in current trends in cage‐chemistry the discussion of reactions in endohedral‐cage compounds is divided into three sections. These are: 1) Endohedral groups that are by themselves functional, 2) endohedral groups that can bind to a transition‐metal complex and 3) endohedral groups that can bind by themselves to a metal. The article closes with an outlook on additional current developments in the field of endohedral‐functionalized cage‐compounds, which may contribute in the future towards reactivity in cage compounds. Cage ; Chemistry ; Surface modification ; Reactivity (psychology) ; Nanotechnology ; Endohedral fullerene ; Transition metal ; Metal ; Computational chemistry ; Combinatorial chemistry ; Organic chemistry ; Molecule ; Catalysis ; Physical chemistry ; Materials science ; Engineering Supramolecular Chemistry and Complexes ; Magnetism in coordination complexes ; Molecular Junctions and Nanostructures
Authors: Federico De Biasi | Michael A. Hope | Claudia E. Avalos | Ganesan Karthikeyan | Gilles Casano | Aditya Mishra | Saumya Badoni | Gabriele Stevanato | Dominik J. Kubicki | Jonas Milani | Jean‐Philippe Ansermet | Aaron J. Rossini | Moreno Lelli | Olivier Ouari | Lyndon Emsley
Source: Journal of the American Chemical Society (article, 2023-06-27)
Field: Chemistry — Spectroscopy

Optically Enhanced Solid-State <sup>1</sup> H NMR Spectroscopy Low sensitivity is the primary limitation to extending nuclear magnetic resonance (NMR) techniques to more advanced chemical and structural studies. Photochemically induced dynamic nuclear polarization (photo-CIDNP) is an NMR hyperpolarization technique where light is used to excite a suitable donor-acceptor system, creating a spin-correlated radical pair whose evolution drives nuclear hyperpolarization. Systems that exhibit photo-CIDNP in solids are not common, and this effect has, up to now, only been observed for <sup>13</sup>C and <sup>15</sup>N nuclei. However, the low gyromagnetic ratio and natural abundance of these nuclei trap the local hyperpolarization in the vicinity of the chromophore and limit the utility for bulk hyperpolarization. Here, we report the first example of optically enhanced solid-state <sup>1</sup>H NMR spectroscopy in the high-field regime. This is achieved via photo-CIDNP of a donor-chromophore-acceptor molecule in a frozen solution at 0.3 T and 85 K, where spontaneous spin diffusion among the abundant strongly coupled <sup>1</sup>H nuclei relays polarization through the whole sample, yielding a 16-fold bulk <sup>1</sup>H signal enhancement under continuous laser irradiation at 450 nm. These findings enable a new strategy for hyperpolarized NMR beyond the current limits of conventional microwave-driven DNP. Hyperpolarization (physics) ; CIDNP ; Chemistry ; Chromophore ; Nuclear magnetic resonance spectroscopy ; Spectroscopy ; Polarization (electrochemistry) ; Solid-state nuclear magnetic resonance ; Spin isomers of hydrogen ; Acceptor ; Spin diffusion ; Nuclear magnetic resonance ; Photochemistry ; Physical chemistry ; Diffusion ; Stereochemistry Advanced NMR Techniques and Applications ; Solid-state spectroscopy and crystallography ; Molecular spectroscopy and chirality
Authors: Priyanka Kolhar | Basavaraja Sannakki | Meenakshi Verma | Siddaramappa Suresha | Mansoor H. Alshehri | Nehad Ali Shah
Source: Nanomaterials (article, 2023-08-02)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Investigation of Structural, Dielectric and Optical Properties of Polyaniline—Magnesium Ferrite Composites A study on the influence of magnesium ferrite nanoparticles on the optical and dielectric attributes of Polyaniline has been conducted. Magnesium nano Ferrite powder is synthesized by the self-propagating solution combustion method. Polyaniline-Magnesium nano ferrite composites are synthesized by chemical oxidative polymerization of aniline with the addition of Magnesium nanoparticles. The samples are characterized with XRD and UV-Vis spectrometer, in the wavelength range of 200-800 nm and studied for optical properties. Dielectric properties are studied in the frequency range of 50 Hz to 5 MHz. X-ray diffraction reveals single phase formation of Magnesium ferrite, whereas Polyaniline shows an amorphous nature. In the XRD of the composites, we see the crystalline peaks of ferrite becoming more intense with the addition of ferrite and whereas the peak of Polyaniline diminishes. The crystallite size is quantified with the Debye-Scherrer formula, and it increases as the content of ferrite in the composites increases. The micro-strain decreases in the composites as the percentage of ferrite enhances in the composites. In the UV-Vis absorption spectra of composites, the peaks of Polyaniline shift to higher wavelength and there is also an absorption band in the spectra of composites corresponding to that of Magnesium ferrite particles. Both direct and indirect band gaps are calculated with the Tauc plot, and both the optical band gap decrease as the percentage of ferrite increases in the composite. The dielectric loss and dielectric constant both decrease with frequency in all the samples, and the dielectric response are in good agreement with Maxwell-Wagner model. Ferrite-polymer composites with both conducting and magnetic properties are considered useful for electromagnetic shielding and microwave absorption. Materials science ; Polyaniline ; Ferrite (magnet) ; Dielectric ; Composite material ; Crystallite ; Band gap ; Magnesium ; Dielectric loss ; Polymerization ; Metallurgy ; Polymer ; Optoelectronics Electromagnetic wave absorption materials ; Conducting polymers and applications ; Dielectric properties of ceramics
Authors: Theophile Niyitanga | Archana Chaudhary | Khursheed Ahmad | Haekyoung Kim
Source: Micromachines (review, 2023-10-06)
Field: Materials Science — Materials Chemistry

Titanium Carbide (Ti3C2Tx) MXene as Efficient Electron/Hole Transport Material for Perovskite Solar Cells and Electrode Material for Electrochemical Biosensors/Non-Biosensors Applications Recently, two-dimensional (2D) MXenes materials have received enormous attention because of their excellent physiochemical properties such as high carrier mobility, metallic electrical conductivity, mechanical properties, transparency, and tunable work function. MXenes play a significant role as additives, charge transfer layers, and conductive electrodes for optoelectronic applications. Particularly, titanium carbide (Ti<sub>3</sub>C<sub>2</sub>T<i><sub>x</sub></i>) MXene demonstrates excellent optoelectronic features, tunable work function, good electron affinity, and high conductivity. The Ti<sub>3</sub>C<sub>2</sub>T<i><sub>x</sub></i> has been widely used as electron transport (ETL) or hole transport layers (HTL) in the development of perovskite solar cells (PSCs). Additionally, Ti<sub>3</sub>C<sub>2</sub>T<i><sub>x</sub></i> has excellent electrochemical properties and has been widely explored as sensing material for the development of electrochemical biosensors. In this review article, we have summarized the recent advances in the development of the PSCs using Ti<sub>3</sub>C<sub>2</sub>T<i><sub>x</sub></i> MXene as ETL and HTL. We have also compiled the recent progress in the fabrication of biosensors using Ti<sub>3</sub>C<sub>2</sub>T<i><sub>x</sub></i>-based electrode materials. We believed that the present mini review article would be useful to provide a deep understanding, and comprehensive insight into the research status. MXenes ; Materials science ; Nanotechnology ; Electrode ; Titanium carbide ; Biosensor ; Work function ; Perovskite (structure) ; Optoelectronics ; Carbide ; Chemistry ; Layer (electronics) ; Composite material MXene and MAX Phase Materials ; 2D Materials and Applications ; Advanced Memory and Neural Computing
Authors: Shaimaa Elsaeed | E. G. Zaki | Ayman A. Diab | Menna-Alla Tarek | Walaa A. E. Omar
Source: Scientific Reports (article, 2023-12-16)
Field: Materials Science — Biomaterials

New polyvinyl alcohol/gellan gum-based bioplastics with guava and chickpea extracts for food packaging Plastic is a fossil-based synthetic polymer that has become an essential material in our daily life. Plastic pollution resulting from the accumulation of plastic objects has become problematic for our environment. Bioplastic can be a biodegradable environmentally friendly alternative for the synthetic plastic. In this paper, bioplastics based on polyvinyl alcohol (PVA)/gellan gum (GG) blend have been produced in three different compositions and their chemical structure, mechanical, morphological and thermal properties have been studied. Glycerol has been used as a plasticizer. To add extra features to the PVA/GG bioplastic, Psidium guajava (guava) leaves, GL, and chickpea, CP, extracts have been added to the PVA/GG (30/70) blend. Water and aqueous ethanol have been used in the extraction of GL and CP, respectively. The addition of the plant's extracts enhanced the tensile properties of the PVA/GG bioplastic. Weathering acceleration tests have been carried out to examine the degradation of the prepared bioplastics. Cytotoxicity studies revealed that the prepared bioplastic is safe to be used in food packaging applications. Water and oxygen permeability for the new PVA/GG bioplastic have also been studied. The addition of the plant extracts (GL and CP extracts) increased the oxygen and water permeability to different extents. Bioplastic life cycle assessment (LCA) and CO<sub>2</sub> emissions in comparison to fossil-based plastic have been investigated. From all the results, PVA/GG based bioplastic proved to be a degradable, safe and effective alternative for fossil-based plastics in food packaging applications. Bioplastic ; Polyvinyl alcohol ; Materials science ; Environmentally friendly ; Food packaging ; Sericulture ; Food science ; Chemistry ; Waste management ; Composite material ; Bombyx mori ; Biology ; Biochemistry Nanocomposite Films for Food Packaging ; Postharvest Quality and Shelf Life Management ; Agricultural and Food Sciences
Authors: Néstor Calabia Gascón | Herman Terryn | Annick Hubin
Source: Next Nanotechnology (review, 2023-06-01)
Field: Materials Science — Polymers and Plastics

The role of PEDOT:PSS in (super)capacitors: A review Supercapacitors are energy storage devices that, in contrast to classical capacitors, are able to deliver larger amounts of energy keeping a fast charge/discharge rates. They can be considered as the meeting point between batteries and classical capacitors. Poly(3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) is one of the most used conductive polymers (CPs) due to its high thermal stability, low electronic resistance and its ease of application. The role of PEDOT:PSS in supercapacitors where it substitutes the liquid electrolyte is a very interesting approach. Not only it results in a better performing but also a safer option than classical electrolytic capacitors. Despite their wide use in this type of devices, the charge storage mechanism of a PEDOT:PSS layer is still not fully understood. When they were conceived, CPs were automatically classified as pseudocapacitors in terms of their capacitive properties. However, recent analysis of the characteristics of PEDOT:PSS has challenged the origin of the capacitive properties. The mixed ionic-electronic conductivity as a result of the two phases present in PEDOT:PSS (PEDOT rich regions and PSS rich regions) translates into the formation of multiple capacitors in the nanometric scale. These contribute to the total capacitance and they resemble the capacitive mechanism of electrochemical double layers capacitors (EDLC). The combination of PEDOT:PSS with the enlarged surface area of a valve metal such as aluminium gives rise to a solid-state polymer capacitor with low equivalent series resistance (ESR), high capacitance and safer operation conditions than the liquid counterparts. This review covers the recent literature on the main two groups of supercapacitors, namely EDLC and pseudocapacitors, and positions PEDOT:PSS according to the latest findings. Additionally, it presents the challenges of achieving the optimal combination of PEDOT:PSS and aluminium towards better solid-state polymer capacitors at the nanoscale. PEDOT:PSS ; Capacitor ; Supercapacitor ; Materials science ; Polystyrene sulfonate ; Capacitance ; Equivalent series resistance ; Polymer capacitor ; Electrolytic capacitor ; Conductive polymer ; Electrolyte ; Capacitive sensing ; Optoelectronics ; Energy storage ; Nanotechnology ; Polymer ; Electrical engineering ; Composite material ; Voltage ; Layer (electronics) ; Electrode ; Chemistry ; Physics Conducting polymers and applications ; Supercapacitor Materials and Fabrication ; Dielectric materials and actuators