jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Alemayehu Kidanemariam | Sungbo Cho
Source: Micromachines (review, 2025-06-24)
Field: Chemistry — Inorganic Chemistry

Recent Advancements in Metal–Organic Framework-Based Microfluidic Chips for Biomedical Applications The integration of metal-organic frameworks (MOFs) with microfluidic technologies has opened new frontiers in biomedical diagnostics and therapeutics. Microfluidic chips offer precise fluid control, low reagent use, and high-throughput capabilities features further enhanced by MOFs' ample surface area, adjustable porosity, and catalytic activity. Together, they form powerful lab-on-a-chip platforms for sensitive biosensing, drug delivery, tissue engineering, and microbial detection. This review highlights recent advances in MOF-based microfluidic systems, focusing on material innovations, fabrication methods, and diagnostic applications. Particular emphasis is placed on MOF nanozymes, which enhance biochemical reactions for multiplexed testing and rapid pathogen identification. Challenges such as stability, biocompatibility, and manufacturing scalability are addressed, along with emerging trends like responsive MOFs, AI-assisted design, and clinical translation strategies. By bridging MOF chemistry and microfluidic engineering, these systems hold great promise for next-generation biomedical technologies. Microfluidics ; Nanotechnology ; Materials science ; Process engineering ; Engineering Metal-Organic Frameworks: Synthesis and Applications ; Nanoplatforms for cancer theranostics ; Advanced biosensing and bioanalysis techniques
Authors: Arige Sumanth | Vikash Mishra | Srungarapu Leela Nagendra | M. S. Ramachandra Rao | Tejendra Dixit
Source: physica status solidi (RRL) - Rapid Research Letters (article, 2025-05-11)
Field: Materials Science — Materials Chemistry

Advancements in P‐type Wide and Ultra‐Wide Bandgap Oxide Semiconductors for Prospective Applications Wide and ultra‐wide bandgap (UWBG) p‐type oxide semiconductors are gaining significant attention due to their unique optoelectronic properties, high thermal stability, large breakdown voltages, and potential for next‐generation device applications. The limited availability of high‐performance p‐type semiconductors has historically constrained optoelectronic advancements, but recent progress in p‐type metal oxides has opened new pathways for innovative technologies. This review explores the latest developments in p‐type wide and UWBG oxide semiconductors, emphasizing their role in emerging applications such as solar‐blind photodetectors, AI‐driven optoelectronic sensors, high‐power electronics, memristors, synaptic devices, and transparent electronics. The review highlights both theoretical and experimental advancements, offering insights into their future impact on optoelectronic and electronic industries. Materials science ; Band gap ; Semiconductor ; Optoelectronics ; Wide-bandgap semiconductor ; Nanotechnology ; Oxide ; Engineering physics ; Engineering ; Metallurgy ZnO doping and properties ; Ga2O3 and related materials ; Semiconductor materials and devices
Authors: Suman Itani | Yibo Zhang | Jiadong Zang
Source: Computational Materials Science (article, 2025-03-30)
Field: Materials Science — Materials Chemistry

Large language model-driven database for thermoelectric materials Thermoelectric effect ; Thermoelectric materials ; Computer science ; Materials science ; Database ; Physics ; Thermodynamics Advanced Thermoelectric Materials and Devices ; Machine Learning in Materials Science ; Gas Sensing Nanomaterials and Sensors
Authors: Pinki Singh | Nisha Shankhwar | Aditi Nachnani | Prashant Singh | Upendra Kumar | Satyendra Singh | Chandan Upadhyay
Source: Progress in Materials Science (article, 2025-06-04)
Field: Materials Science — Biomaterials

Advances in relaxation and memory effects of magnetic nanoparticles for biomedical applications Materials science ; Nanotechnology ; Nanoparticle ; Magnetic nanoparticles ; Relaxation (psychology) ; Magnetic relaxation ; Magnetization ; Magnetic field ; Neuroscience ; Psychology Nanoparticle-Based Drug Delivery ; Characterization and Applications of Magnetic Nanoparticles ; Magnetic Properties and Synthesis of Ferrites
Authors: Humaira Khan | Simona Piccolella | Severina Pacifico
Source: Materials Today Sustainability (article, 2025-08-11)
Field: Materials Science — Materials Chemistry

Harnessing plant extracts for green nanoparticle synthesis: Toward a sustainable future Nanotechnology is revolutionizing diverse scientific fields, yet conventional nanoparticle (NP) synthesis remains energy-intensive and environmentally hazardous. This has fuelled a shift toward sustainable, biogenic approaches, with plant-mediated NP synthesis emerging as a promising alternative. Leveraging the rich diversity of plant-derived phytochemicals, such as flavonoids, polyphenols, and alkaloids, this method offers a sustainable, cost-effective and eco-friendly route to nanoparticle production. However, despite its potential, key challenges remain: the incomplete characterization of plant extracts hampers reproducibility, control over NP morphology, and large-scale implementation. While many studies report successful NP synthesis, a precise understanding of the specialized metabolites involved is still lacking. Bridging this knowledge gap is crucial for optimizing NP properties and expanding their biomedical, catalytic, and industrial applications. This review critically examines the role of specialized plant metabolites in NP synthesis, detailing analytical techniques, such as LC-MS, FTIR, and NMR, for their characterization. Scalability remains a key challenge in plant-mediated nanoparticle synthesis, with reproducibility often limited by non-standardized extraction methods. Strategies such as protocol harmonization, the integration of advanced analytical tools, and the application of artificial intelligence (AI) can significantly enhance consistency and predictability. Recent publication trends show growing interest in green synthesis, particularly in applications across healthcare, food nanotechnology, and smart packaging. Addressing current limitations and deepening the understanding of plant-derived metabolites could shift the field from empirical trials to a standardized, scalable, and industrially viable green technology, supporting the development of sustainable materials. • Green synthesis strategies of plant-based nanoparticles are critically reviewed. • Phytochemical roles and mechanisms in nanoparticle synthesis are explored. • Analytical methods for characterizing green nanoparticles are summarized. • Applications of plant-synthesized nanoparticles are briefly highlighted. • Scalable, sustainable nanoformulations from plants are proposed. Nanoparticle ; Nanotechnology ; Environmental science ; Business ; Materials science Nanoparticles: synthesis and applications ; Chemistry and Chemical Engineering
Authors: Sabyasachi Chakraborty | Itay Almog | Renana Gershoni‐Poranne
Source: Journal of Chemical Information and Modeling (article, 2025-05-23)
Field: Materials Science — Materials Chemistry

COMPAS-4: A Data Set of (BN) <sub>1</sub> Substituted <i>Cata</i> -Condensed Polybenzenoid Hydrocarbons─Data Analysis and Feature Engineering Incorporation of a boron-nitrogen (BN) pair into polycyclic aromatic hydrocarbons is a common approach for modulating their electronic properties. However, a conceptual and quantitative framework rationalizing the observed effects has not been developed, and general structure-property relationships remain elusive. In this work, we perform a data-driven investigation that leads to concrete principles for rational design of (BN)<sub>1</sub>-PBHs with targeted properties. We construct a new chemical database, COMPAS-4, which contains the geometries and properties of all possible (BN)<sub>1</sub>-PBH isomers up to 6 rings, calculated at both the GFN1-xTB and density functional theory (DFT) (CAM-B3LYP/def2-SVP) levels of theory. We investigate the influence of BN-substitution on various molecular properties, including their molecular orbital energies and aromaticity, and define specific structural features that determine these properties. Notably, all of these features are chemically intuitive and simple to extract from the structure of the molecule, without any prior computation. We find that the most influential feature is the number of rings whose cyclic delocalization is disturbed as a result of the substitution. Data set ; Feature (linguistics) ; Set (abstract data type) ; Feature engineering ; Computer science ; Data mining ; Chemistry ; Pattern recognition (psychology) ; Artificial intelligence ; Philosophy Machine Learning in Materials Science ; Organoboron and organosilicon chemistry ; Computational Drug Discovery Methods
Authors: Esther Ugo Alum | Olisa Alfred Nwuruku | Okechukwu Paul-Chima Ugwu | Daniel Ejim Uti | Benedict Nnachi Alum | Nzubechukwu Edwin
Source: Phytomedicine Plus (article, 2025-05-28)
Field: Materials Science — Biomaterials

Harnessing nature: plant-derived nanocarriers for targeted drug delivery in cancer therapy : The rising global burden of cancer underscores the need for innovative therapies that address limitations of conventional treatments, such as drug resistance, systemic toxicity, and poor bioavailability. Plant-derived nanocarriers (PDNs) offer a sustainable, biocompatible, and effective platform for targeted drug delivery. This review explores the classifications, mechanisms, and therapeutic potential of PDNs in enhancing cancer treatment outcomes. : A comprehensive literature review was conducted using databases including Scopus, Web of Science, and PubMed, focusing on peer-reviewed publications from the past decade. Various PDN types such as phytosomes, lipid-based nanoparticles, polymeric nanoparticles, and exosome-like nanovesicles were examined. Mechanisms of drug encapsulation, release, and tumor targeting were analyzed alongside relevant preclinical and clinical case studies. : PDNs improve drug stability, solubility, and targeted delivery, minimizing toxicity to healthy tissues. Case studies highlight successful delivery of agents like curcumin, doxorubicin, and plant-derived alkaloids. Key challenges include scalability, stability, and regulatory hurdles. Emerging solutions such as green synthesis and integration with artificial intelligence are discussed. : PDNs represent a promising frontier in cancer therapy by merging nanotechnology with natural biomaterials to enhance efficacy and personalization while reducing side effects. Overcoming current limitations could accelerate clinical adoption and revolutionize cancer treatment. Nanocarriers ; Drug delivery ; Cancer therapy ; Cancer drugs ; Targeted drug delivery ; Drug ; Cancer ; Medicine ; Nanotechnology ; Pharmacology ; Internal medicine ; Materials science Nanoparticle-Based Drug Delivery ; Graphene and Nanomaterials Applications ; Nanoparticles: synthesis and applications
Authors: Yanjing Liu | Jing Xu | Yuanqiang Guo
Source: International Journal of Biological Macromolecules (review, 2025-07-16)
Field: Materials Science — Biomaterials

Natural polysaccharide-based nano-drug delivery systems: Innovative strategies and research advances in cancer therapy – A review Cancer therapy ; Drug delivery ; Cancer ; Nanotechnology ; Polysaccharide ; Medicine ; Biochemical engineering ; Chemistry ; Engineering ; Materials science ; Internal medicine ; Biochemistry Nanoparticle-Based Drug Delivery ; Polysaccharides and Plant Cell Walls ; Advanced Drug Delivery Systems
Authors: Panpan Jiang | Nan Gao | Gang Chang | Yuxiang Wu
Source: Biosensors (review, 2025-04-29)
Field: Materials Science — Polymers and Plastics

Biosensors for Early Detection of Parkinson’s Disease: Principles, Applications, and Future Prospects Parkinson's disease (PD), a neurodegenerative disorder marked by the progressive loss of dopaminergic neurons in the substantia nigra, imposes substantial economic burdens, including both direct and indirect costs. The medical community currently lacks a definitive cure for Parkinson's disease, and early detection is crucial for timely intervention and disease management. As innovative diagnostic tools, biosensors have shown great potential in detecting PD at its early stages. This review comprehensively summarizes recent advances in biosensors for the early detection of PD, with a particular focus on the detection of two key biomarkers: dopamine (DA) and α-synuclein (α-syn). Furthermore, it illustrates a variety of nanotechnology-based biosensors, including optical, electrochemical, and transistor biosensors, detailing their underlying principles, advantages, limitations, and applications in PD detection. Moreover, the review explores the challenges and prospects of advancing biosensors for early PD diagnosis. Parkinson's disease ; Biosensor ; Disease ; Nanotechnology ; Neuroscience ; Medicine ; Biology ; Materials science ; Pathology Conducting polymers and applications ; Electrochemical sensors and biosensors ; Electrochemical Analysis and Applications
Authors: Ping Li | Qiushi Wang
Source: Colloids and Interfaces (article, 2025-07-19)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Novel Structural Janus Hydrogels for Battery Applications: Structure Design, Properties, and Prospects Janus hydrogels, defined by their asymmetric architectures and bifunctional interfaces, have emerged as a transformative class of solid-state electrolytes in electrochemical energy storage. By integrating spatially distinct chemomechanical and ionic functionalities within a single matrix, they overcome the intrinsic limitations of conventional isotropic hydrogels, offering enhanced interfacial stability, directional ion transport, and dendrite suppression in lithium- and zinc-based batteries. This mini-review systematically highlights recent breakthroughs in Janus hydrogel design, including interfacial polymerization and layer-by-layer assembly, which collectively enable precise modulation of crosslinking gradients and ion transport pathways. This review uniquely frames Janus hydrogels from a battery-centric and interface-engineering perspective. It elucidates key structure–function correlations, identifies current limitations in scalable fabrication and electrochemical longevity, and outlines future directions toward intelligent, multifunctional platforms for next-generation flexible and biointegrated energy systems. Janus ; Self-healing hydrogels ; Battery (electricity) ; Materials science ; Nanotechnology ; Engineering ; Computer science ; Physics ; Polymer chemistry Supercapacitor Materials and Fabrication ; Advanced battery technologies research ; Pickering emulsions and particle stabilization
Authors: Zhiyun Zou | Xiaojun Bi | Huan Ma | Ligang Chen | Hai Bo Jin | Shun Gong | Xinning Li | Xiyu Liu
Source: International Journal of Nanomedicine (review, 2025-07-01)
Field: Materials Science — Materials Chemistry

Recent Advances in Nanozymes for the Treatment of Atherosclerosis Atherosclerosis (AS) is a complex, multifactorial cardiovascular disease characterized by lipid accumulation, chronic inflammation, oxidative stress, and endothelial dysfunction. Conventional therapies, including lipid-lowering and anti-inflammatory agents, offer limited efficacy due to inadequate lesion targeting, low bioavailability, and systemic side effects. Nanozymes, which engineered nanomaterials with intrinsic enzyme-mimetic catalytic activities have recently emerged as a transformative therapeutic strategy capable of simultaneously modulating oxidative stress, inflammation, and lipid metabolism. This review comprehensively summarizes recent advances in nanozyme-based interventions for AS, focusing on representative systems such as Prussian blue, cerium oxide, selenium-based, and multifunctional composite nanozymes. We critically discuss their design principles, catalytic mechanisms, lesion-targeting strategies, and therapeutic outcomes in preclinical models. Additionally, we highlight key translational challenges, including biosafety concerns, pharmacokinetic limitations, and manufacturing standardization, which currently impede clinical application. By integrating catalytic activity with targeted delivery and microenvironment-responsive functionalities, nanozymes offer a promising paradigm for precision therapy in AS. Future research should prioritize enhancing biocompatibility, optimizing therapeutic specificity, and establishing scalable, reproducible fabrication methods to facilitate clinical translation. This review aims to provide a systematic framework and insightful guidance for advancing nanozyme-based therapeutics toward clinical application in cardiovascular disease management. Nanotechnology ; Materials science ; Medicine Advanced Nanomaterials in Catalysis ; Nanoplatforms for cancer theranostics ; Nanocluster Synthesis and Applications
Authors: S.A.M. Abdel-Hameed | Fatma H. Margha | Ola N. Almasarawi | M. A. Marzouk
Source: Journal of Inorganic and Organometallic Polymers and Materials (article, 2025-01-31)
Field: Materials Science — Materials Chemistry

Synthesis, Characterization, and Photoluminescence Properties of High and Low-Temperature Dimorphs of Pb2WO5 Glass-Ceramic for Photocatalytic Application Abstract In this study, pure Pb 2 WO 5 with its two dimorphs, high temperature (HT) and low temperature (LT) forms, were successfully crystallized via melt-quenching technique in the system PbO. WO 3 . Al 2 O 3 . The influence of adding definite amounts of different transition metal oxides (TMO) such as ZnO, TiO 2 , CuO, MnO 2, and V 2 O 5 on the crystalline structure, optical, and photocatalytic activity were investigated. X-ray diffraction revealed a high degree of crystallization of pure Pb 2 WO 5 in undoped and ZnO, TiO 2 , CuO, and MnO 2 -doped samples. Only the V 2 O 5 -doped sample revealed crystallization of PbWO 4 beside Pb 2 WO 5 . LT- Pb 2 (WO 5 ) is the preferred isomorph in the undoped and ZnO, TiO 2 , CuO, and MnO 2 -doped samples, while HT- Pb 2 WO 5 is preferred in the V 2 O 5 -doped sample. Scanning Electron Microscopy (SEM) depicted an undeveloped rectangular pillar with a crystal size of 400–900 nm. Energy-Dispersive X-ray Spectroscopy (EDX) analysis certifies the existence of transition metal in the crystals at the expanse of Pb ions. Photoluminescence measurements under ultraviolet (UV) excitation revealed an emission band at 470 nm for undoped sample and exhibited a series of peaks spanning from 400 nm to 620 nm for doped samples. The International Commission on Illumination (CIE) chromaticity coordinates for all the samples are situated within the blue color region of the chromaticity diagram. The undoped sample displays CIE coordinates at (0.117, 0.091), corresponding to a deep blue hue; while the doped samples are shifted towards the light blue area of the chromaticity diagram. Utilizing ultraviolet-visible (UV-Vis) diffused reflectance, the optical bandgap energy (E opt ) for all glass-ceramic samples was estimated, revealing values within the semiconductor range (2.52–3.01 eV). Photocatalytic activity, evaluated through methyl orange (MO) degradation under UV light. The undoped sample revealed a higher degradation efficiency (33.7% after 3 h). This study is thus considered a significant step toward the facile synthesis of moderately efficient UV light novel photocatalysts, semiconducting materials, and photoluminescent glass-ceramics. Chromaticity ; Materials science ; Photoluminescence ; Analytical Chemistry (journal) ; Doping ; Photocatalysis ; Crystallization ; X-ray photoelectron spectroscopy ; Scanning electron microscope ; Chemical engineering ; Optics ; Chemistry ; Optoelectronics ; Composite material Luminescence Properties of Advanced Materials ; Glass properties and applications ; Pigment Synthesis and Properties
Authors: Muhammad Hassnain | Asad Ali | Muhammad Rizwan Azhar | Abdulrahman Abutaleb | Muhammad Mubashir
Source: Global Challenges (review, 2025-04-17)
Field: Materials Science — Materials Chemistry

Challenges and Perspectives on Photocatalytic Membrane Reactors for Volatile Organic Compounds Degradation and Nitrogen Oxides Treatment Air pollution is a pressing environmental and public health issue, with volatile organic compounds (VOCs) and nitrogen oxides (NO <i><sub>x</sub></i> ) being among the most hazardous airborne pollutants. Photocatalytic membrane reactors (PMRs) have emerged as a promising technology for air purification due to their ability to integrate photocatalytic degradation and membrane separation in a single system. This paper provides a comprehensive review of the advancements, challenges, and future prospects of PMR technology for VOC degradation and NO <i><sub>x</sub></i> treatment. Various photocatalytic membranes and their fabrication techniques, including material selection, structural modifications, and catalyst immobilization strategies, are critically analyzed. The study further explores different PMR configurations, operational parameters, and their efficiency in air treatment applications. A theoretical PMR test system is also presented to evaluate design optimization strategies. Despite its potential, challenges such as membrane fouling, catalyst deactivation, and scale-up limitations remain critical barriers to widespread adoption. Future trends focus on enhancing photocatalytic performance, developing cost-effective materials, and optimizing reactor designs to facilitate large-scale industrial applications of PMRs. Photocatalysis ; Fouling ; Hazardous waste ; Degradation (telecommunications) ; Membrane reactor ; Water treatment ; Pollutant ; Materials science ; Waste management ; Catalysis ; Membrane ; Nanotechnology ; Process engineering ; Environmental science ; Environmental engineering ; Chemistry ; Engineering ; Organic chemistry Catalytic Processes in Materials Science ; Advanced Photocatalysis Techniques ; Gas Sensing Nanomaterials and Sensors
Authors: Zhaoyang Yu | Tao Fang | Wenhan Cao
Source: Advanced Materials Technologies (article, 2025-02-20)
Field: Materials Science — Materials Chemistry

Flexible and Wearable Devices Based on Colloidal Quantum Dots Abstract A significant class of semiconductor nanostructures, colloidal quantum dots (CQDs), which exhibit narrow emission spectrum and tunable emission frequency, are utilized for numerous flexible and wearable applications including state‐of‐the‐art display, biological sensing, showcasing great prospects in physiological measurement, health monitoring, and rehabilitation. Interestingly, synthesizing these semiconductor particles using methods such as hot injection as colloids can directly tune their optical properties and emission wavelengths by controlling their sizes, which greatly contributes to materials production simplicity and scalability. Importantly, from a device perspective, due to the advantages of solution‐processed synthesis, and patterning methods such as inkjet printing, CQDs can be combined with soft polymeric substrates, or hierarchical structures in a facile manner, offering extraordinary device flexibility and portability. As optoelectronic devices, CQD can function as photoresistors, phototransistors, or through other mechanisms which convert light between other forms of energy, enabling highly sensitive detection applications. In this Review, synthetic approaches are summarized for CQDs, flexible device fabrication techniques, detection mechanisms, and application scenarios. Furthermore, the challenges associated with these technologies, such as device stability and cost‐efficiency are discussed, and present this outlook on the future trends of CQD devices including multi‐functional integration, as a constituent component of flexible and wearable devices. Quantum dot ; Wearable computer ; Wearable technology ; Nanotechnology ; Colloid ; Computer science ; Materials science ; Engineering ; Embedded system ; Chemical engineering Quantum Dots Synthesis And Properties ; Nanocluster Synthesis and Applications ; Gold and Silver Nanoparticles Synthesis and Applications