jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Bowen Li | Zhong Lin Wang | Yicong Luo | Hanlin Wei | Jianzhong Chen | Delong Liu | Wanbin Zhang
Source: Nature Communications (article, 2024-06-28)
Field: Chemistry — Inorganic Chemistry

Nickel-catalyzed asymmetric hydrogenation for the preparation of α-substituted propionic acids Transition metal-catalyzed asymmetric hydrogenation is one of the most efficient methods for the preparation of chiral α-substituted propionic acids. However, research on this method, employing cleaner earth-abundant metal catalysts, is still insufficient in both academic and industrial contexts. Herein, we report an efficient nickel-catalyzed asymmetric hydrogenation of α-substituted acrylic acids affording the corresponding chiral α-substituted propionic acids with up to 99.4% ee (enantiomeric excess) and 10,000 S/C (substrate/catalyst). In particular, this method can be used to obtain (R)-dihydroartemisinic acid with 99.8:0.2 dr (diastereomeric ratio) and 5000 S/C, which is an essential intermediate for the preparation of the antimalarial drug Artemisinin. The reaction mechanism has been investigated via experiments and DFT (Density Functional Theory) calculations, which indicate that the protonolysis of the C-Ni bond of the key intermediate via an intramolecular proton transfer from the carboxylic acid group of the substrate, is the rate-determining step. Catalysis ; Nickel ; Combinatorial chemistry ; Chemistry ; Materials science ; Organic chemistry Asymmetric Hydrogenation and Catalysis ; Surface Chemistry and Catalysis ; Catalysis for Biomass Conversion
Authors: Ivo Fukala | Igor Kučera
Source: Molecules (article, 2024-05-13)
Field: Materials Science — Biomaterials

Natural Polyhydroxyalkanoates—An Overview of Bacterial Production Methods Polyhydroxyalkanoates (PHAs) are intracellular biopolymers that microorganisms use for energy and carbon storage. They are mechanically similar to petrochemical plastics when chemically extracted, but are completely biodegradable. While they have potential as a replacement for petrochemical plastics, their high production cost using traditional carbon sources remains a significant challenge. One potential solution is to modify heterotrophic PHA-producing strains to utilize alternative carbon sources. An alternative approach is to utilize methylotrophic or autotrophic strains. This article provides an overview of bacterial strains employed for PHA production, with a particular focus on those exhibiting the highest PHA content in dry cell mass. The strains are organized according to their carbon source utilization, encompassing autotrophy (utilizing CO<sub>2</sub>, CO) and methylotrophy (utilizing reduced single-carbon substrates) to heterotrophy (utilizing more traditional and alternative substrates). Polyhydroxyalkanoates ; Autotroph ; Petrochemical ; Heterotroph ; Carbon fibers ; Bioplastic ; Carbon source ; Biochemical engineering ; Chemistry ; Microorganism ; Pulp and paper industry ; Food science ; Bacteria ; Materials science ; Waste management ; Biochemistry ; Biology ; Organic chemistry ; Engineering biodegradable polymer synthesis and properties ; Carbon dioxide utilization in catalysis ; Electrospun Nanofibers in Biomedical Applications
Authors: Augustine Innalegwu Daniel | Lizex Hüsselmann | Oluwatosin Kudirat Shittu | Arun Gokul | Marshall Keyster | Ashwil Klein
Source: Journal of Crop Science and Biotechnology (article, 2024-02-26)
Field: Materials Science — Materials Chemistry

Application of nanotechnology and proteomic tools in crop development towards sustainable agriculture Abstract The increase in global population which translates to increased demand for food called for urgent attention from key players and policy makers in agricultural sector. Also, the effects of climate change and its consequent biotic and abiotic stresses in plants has greatly affect the sustainability of agriculture and production of food. These challenges require novel and sustainable approaches to improve the quality and yield of crops. The vast application of nanoparticles in different fields of study is attributed to their distinct chemical and physical characteristics. However, in agriculture, their application is limited because of their safety concern. Currently, research is tailored to study the response of plants to various nanoparticle treatments; however, these studies are inconclusive due to limited knowledge on the mechanisms of plant–nanoparticle interactions. Recently, studies on nanobiotechnology have taken a new dimension from preliminary bioassay experiments to more complex, research-oriented studies using various omics tools. Changes in protein expression caused by plant–nanoparticle interaction at any developmental stages, or tissue types may be investigated using suitable proteomics techniques. This review discussed the various applications of nanotechnology and proteomic tools in plant growth and development. Plant–nanoparticle interactions and the application of nanoparticles and proteomic tools in genetic engineering of plants to attain agricultural sustainability and food safety are also discussed. Informative and thorough understanding of plant–nanoparticle interaction will serve as a blueprint that will enable plant scientist and genetic engineers to develop plant biomarkers and explore their potential application for crop improvement. Agriculture ; Biotechnology ; Sustainability ; Nanobiotechnology ; Nanotechnology ; Proteomics ; Biochemical engineering ; Sustainable agriculture ; Biology ; Engineering ; Nanoparticle ; Materials science ; Ecology Nanoparticles: synthesis and applications ; Polymer-Based Agricultural Enhancements ; Legume Nitrogen Fixing Symbiosis
Authors: Eleni Nestoros | Fabio De Moliner | Ferran Nadal‐Bufí | Deborah Seah | M. Carmen Ortega‐Liebana | Zhiming Cheng | Sam Benson | Catherine Adam | Larissa Maierhofer | Kostiantyn Kozoriz | Jun‐Seok Lee | Asier Unciti‐Broceta | Marc Vendrell
Source: Nature Communications (article, 2024-09-03)
Field: Materials Science — Materials Chemistry

Tuning singlet oxygen generation with caged organic photosensitizers Controlling the succession of chemical processes with high specificity in complex systems is advantageous for widespread applications, from biomedical research to drug manufacturing. Despite synthetic advances in bioorthogonal and photochemical methodologies, there is a need for generic chemical approaches that can universally modulate photodynamic reactivity in organic photosensitizers. Herein we present a strategy to fine-tune the production of singlet oxygen in multiple photosensitive scaffolds under the activation of bioresponsive and bioorthogonal stimuli. We demonstrate that the photocatalytic activity of nitrobenzoselenadiazoles can be fully blocked by site-selective incorporation of electron-withdrawing carbamate moieties and restored on demand upon uncaging with a wide range of molecular triggers, including abiotic transition-metal catalysts. We also prove that this strategy can be expanded to most photosensitizers, including diverse structures and spectral properties. Finally, we show that such advanced control of singlet oxygen generation can be broadly applied to the photodynamic ablation of human cells as well as to regulate the release of singlet oxygen in the semi-synthesis of natural product drugs. Singlet oxygen ; Bioorthogonal chemistry ; Photodynamic therapy ; Photosensitizer ; Combinatorial chemistry ; Chemistry ; Photochemistry ; Natural product ; Organic synthesis ; Reactivity (psychology) ; Catalysis ; Nanotechnology ; Materials science ; Oxygen ; Organic chemistry Photochromic and Fluorescence Chemistry ; Nanoplatforms for cancer theranostics ; Click Chemistry and Applications
Authors: Marina Garrido | Alicia Naranjo | Emilio M. Pérez
Source: Chemical Science (article, 2024-01-01)
Field: Materials Science — Materials Chemistry

Characterization of emerging 2D materials after chemical functionalization The chemical modification of 2D materials has proven a powerful tool to fine tune their properties. With this motivation, the development of new reactions has moved extremely fast. The need for speed, together with the intrinsic heterogeneity of the samples, has sometimes led to permissiveness in the purification and characterization protocols. In this review, we present the main tools available for the chemical characterization of functionalized 2D materials, and the information that can be derived from each of them. We then describe examples of chemical modification of 2D materials other than graphene, focusing on the chemical description of the products. We have intentionally selected examples where an above-average characterization effort has been carried out, yet we find some cases where further information would have been welcome. Our aim is to bring together the toolbox of techniques and practical examples on how to use them, to serve as guidelines for the full characterization of covalently modified 2D materials. Surface modification ; Characterization (materials science) ; Nanotechnology ; Materials science ; Chemistry ; Physical chemistry 2D Materials and Applications ; MXene and MAX Phase Materials ; Graphene research and applications
Authors: Christin Gellrich | Leonid Shupletsov | Przemysław Galek | Ahmed Bahrawy | Julia Grothe | Stefan Kaskel
Source: Advanced Materials (article, 2024-05-03)
Field: Materials Science — Electronic, Optical and Magnetic Materials

A Precursor‐Derived Ultramicroporous Carbon for Printing Iontronic Logic Gates and Super‐Varactors A liquid precursor for 3D printing ultramicroporous carbons (pore width <0.7 nm) to create a novel in-plane capacitive-analog of semiconductor-based diodes (CAPodes) is presented. This proof-of-concept integrates functional EDLCs into microstructured iontronic devices. The working principle is based on selective ion-sieving, controlling the size of the electrolyte ions, and the nanoporous sieving carbon's pore size. By blocking bulky electrolyte ions from entering the sub-nanometer pores, a unidirectional charging characteristic with controllable ion flux is achieved, leading to diodic U-I characteristics with a high rectification ratio. The liquid precursor approach enables successful printing of miniaturized in-plane CAPodes. A combination of inkjet and extrusion printing techniques with suitable inks is explored to fabricate electrode materials with engineered porosity. Deliberate fine-tuning of the ultramicroporous carbon's porosity and surface area is achieved using a customized carbon precursor and CO<sub>2</sub> etching techniques. Electrochemical evaluation of the printed CAPodes demonstrates successful miniaturization compared with macroscopic film assembly. 3D manufacturing and miniaturization allow for the integration of CAPodes into logic gate circuits (OR, AND). For the first time, these switchable devices are used as variable capacitors in a high-pass filter application, adjusting the cut-off frequency of applied alternating voltage analogous to an I-MOS varactor. Materials science ; Miniaturization ; Nanotechnology ; Electrolyte ; Porosity ; Supercapacitor ; Optoelectronics ; Nanoporous ; Diode ; Etching (microfabrication) ; Electrode ; Capacitance ; Composite material Supercapacitor Materials and Fabrication ; Catalytic Processes in Materials Science ; Electrocatalysts for Energy Conversion
Authors: Beibei Zhan | Xiaosi Qi | Jingliang Yang | Xiu Gong | Junfei Ding | Yanli Chen | Fuzhong Wu | Wei Zhong
Source: Nano Research (article, 2024-12-26)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Advancing microwave absorption: Innovative strategies spanning nano-micro engineering to metamaterial design With the widespread adoption of communication technology, the potential hazards of electromagnetic (EM) radiation to human health and electronic devices operation have also emerged. Therefore, microwave absorption (MA) materials are becoming increasingly vital in the current electronic information age. Currently, extensive researches have been conducted on the MA mechanisms and optimized strategies, leading to significant advancements in improving MA performance. However, there is a lack of systematic summary of various innovative engineering strategies from nano-micro scale to metamaterial. Typically, nano-micro engineering techniques readily introduce heterointerfaces, components, or defects, etc. to boost dielectric loss and/or magnetic loss. And macroscopic strategy focuses on crafting more porous three-dimensional structures (foams, aerogels, films, etc.), which are beneficial for fine-tuning intrinsic impedance and triggering multiple reflections/scattering of EM wave (EMW). While metamaterial design featuring periodic layouts and sub-wavelength scales can also lead to energy loss via EMW resonances. Hence, in this review, we aim to provide a detailed overview of various engineering strategies for enhancing MA performance from nano-micro engineering to macroscopic strategies to metamaterial design. Furthermore, we elaborate the present challenges faced by MA technology and discuss potential future development opportunities and trends. It is our hope that this paper will offer insights and direction for the ongoing improvement of MA performance and achieving practical applications. Microwave ; Metamaterial ; Nano- ; Nanotechnology ; Materials science ; Absorption (acoustics) ; Engineering physics ; Engineering ; Optoelectronics ; Composite material ; Telecommunications Electromagnetic wave absorption materials
Authors: Zahra Younesi | Saeed Mohammadzadeh | Milad Ghani | Mahmood Tajbakhsh | Habibollah Younesi
Source: Microchemical Journal (article, 2024-12-21)
Field: Chemistry — Analytical Chemistry

Magnetic MCM-41 functionalized with ureathiosemicarbazone monohydrate as the sorbent for magnetic solid-phase extraction of triazole fungicides from fruit samples followed by measuring using high performance liquid chromatography Sorbent ; Solid phase extraction ; Extraction (chemistry) ; Triazole ; Fungicide ; Chromatography ; High-performance liquid chromatography ; Chemistry ; Materials science ; Organic chemistry ; Adsorption ; Botany ; Biology Analytical chemistry methods development ; Pesticide Residue Analysis and Safety ; Analytical Chemistry and Chromatography
Authors: Flavia Carton | Manuela Rizzi | Elena Canciani | Gianluca Sieve | Dalila Di Francesco | Simona Casarella | Luca Di Nunno | Francesca Boccafoschi
Source: International Journal of Molecular Sciences (review, 2024-10-24)
Field: Materials Science — Biomaterials

Use of Hydrogels in Regenerative Medicine: Focus on Mechanical Properties Bioengineered materials represent an innovative option to support the regenerative processes of damaged tissues, with the final objective of creating a functional environment closely mimicking the native tissue. Among the different available biomaterials, hydrogels represent the solution of choice for tissue regeneration, thanks to the easy synthesis process and the highly tunable physical and mechanical properties. Moreover, hydrogels are biocompatible and biodegradable, able to integrate in biological environments and to support cellular interactions in order to restore damaged tissues' functionality. This review offers an overview of the current knowledge concerning hydrogel synthesis and characterization and of the recent achievements in their experimental use in supporting skin, bone, cartilage, and muscle regeneration. The currently available in vitro and in vivo results are of great interest, highlighting the need for carefully designed and controlled preclinical studies and clinical trials to support the transition of these innovative biomaterials from the bench to the bedside. Self-healing hydrogels ; Regenerative medicine ; Focus (optics) ; Biomedical engineering ; Nanotechnology ; Chemistry ; Materials science ; Medicine ; Biology ; Cell biology ; Stem cell ; Physics ; Polymer chemistry Electrospun Nanofibers in Biomedical Applications ; Bone Tissue Engineering Materials ; Periodontal Regeneration and Treatments
Authors: Joachim F. R. Van Guyse | Saed Abbasi | Kazuko Toh | Zlata Nagorna | Junjie Li | Anjaneyulu Dirisala | Sabina Quader | Satoshi Uchida | Kazunori Kataoka
Source: Angewandte Chemie International Edition (article, 2024-04-23)
Field: Materials Science — Polymers and Plastics

Facile Generation of Heterotelechelic Poly(2‐Oxazoline)s Towards Accelerated Exploration of Poly(2‐Oxazoline)‐Based Nanomedicine Controlling the end-groups of biocompatible polymers is crucial for enabling polymer-based therapeutics and nanomedicine. Typically, end-group diversification is a challenging and time-consuming endeavor, especially for polymers prepared via ionic polymerization mechanisms with limited functional group tolerance. In this study, we present a facile end-group diversification approach for poly(2-oxazoline)s (POx), enabling quick and reliable production of heterotelechelic polymers to facilitate POxylation. The approach relies on the careful tuning of reaction parameters to establish differential reactivity of a pentafluorobenzyl initiator fragment and the living oxazolinium chain-end, allowing the selective introduction of N-, S-, O-nucleophiles via the termination of the polymerization, and a consecutive nucleophilic para-fluoro substitution. The value of this approach for the accelerated development of nanomedicine is demonstrated through the synthesis of well-defined lipid-polymer conjugates and POx-polypeptide block-copolymers, which are well-suited for drug and gene delivery. Furthermore, we investigated the application of a lipid-POx conjugate for the formulation and delivery of mRNA-loaded lipid nanoparticles for immunization against the SARS-COV-2 virus, underscoring the value of POx as a biocompatible polymer platform. Oxazoline ; Nanomedicine ; Materials science ; Nanotechnology ; Nanoparticle ; Chemistry ; Catalysis ; Organic chemistry Synthesis and properties of polymers ; Silicone and Siloxane Chemistry ; Dendrimers and Hyperbranched Polymers
Authors: Neveen Farrage | Nahed H. Teleb | W. A. Abd El-Ghany
Source: Optical and Quantum Electronics (article, 2024-01-27)
Field: Materials Science — Polymers and Plastics

Investigation of the structural and optical properties of Sb2S3/PVA/PVP nanocomposites blended sheets for optoelectronic applications Abstract Sb 2 S 3 chalcogenide Nanopowder was prepared at low temperatures using the chemical co-precipitation method. PVA/PVP polymeric sheets have been prepared with a constant ratio of 2:1 as a host matrix to incorporate Sb 2 S 3 NPS with a ratio of 0, 1, 3, and 5 wt% via solution casting technique. The X-ray diffraction (XRD) pattern revealed that the prepared Sb 2 S 3 powder belongs to an orthorhombic crystalline structure as a major phase, with a crystal size of 24 nm. The microstructure of the powder as well as 5 wt% Sb 2 S 3 /PVA/PVP was investigated using the transmission electron microscope. The Fourier transform infrared spectra of the prepared sheets revealed the success of the interaction between the filler Sb 2 S 3 material with the PVA/PVP as a polymer host matrix. The transmission and reflection spectra of the polymeric Sb 2 S 3 /PVA/PVP sheets measured in the wavelength range 200–2500 nm have been used to calculate the optical band gap energy and refractive index as a function in the Sb 2 S 3 wt%. The Tauc model and the absorption spectrum fitting model were employed to accurately determine the variation of the optical band gap value with Sb 2 S 3 filler percent. Wemple-DiDomenico single-oscillator and Spitzer-Fan, models were applied to analyze the refractive index as a function of the Sb 2 S 3 filling wt%, whereby the dispersion parameters, $${E}_{d},{E}_{o}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:msub> <mml:mi>E</mml:mi> <mml:mi>d</mml:mi> </mml:msub> <mml:mo>,</mml:mo> <mml:msub> <mml:mi>E</mml:mi> <mml:mi>o</mml:mi> </mml:msub> </mml:mrow> </mml:math> as well as the optical high-frequency dielectric constant, $${\varepsilon }_{L}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>ε</mml:mi> <mml:mi>L</mml:mi> </mml:msub> </mml:math> carrier concentration to the effective mass ratio, $$N/{m}^{*}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:mrow> <mml:mi>N</mml:mi> <mml:mo>/</mml:mo> <mml:msup> <mml:mrow> <mml:mi>m</mml:mi> </mml:mrow> <mml:mrow> <mml:mrow/> <mml:mo>∗</mml:mo> </mml:mrow> </mml:msup> </mml:mrow> </mml:math> were evaluated. A graphical representation of the optical conductivity was also present. The obtained data indicate the possibility of using the prepared Sb 2 S 3 /PVA/PVP nanocomposite sheets for optoelectronic applications and optical devices. Materials science ; Nanocomposite ; Optoelectronics ; Nanotechnology Polymer Nanocomposite Synthesis and Irradiation ; Chalcogenide Semiconductor Thin Films ; Nonlinear Optical Materials Research
Authors: Maryam Hajfathalian | Katherine J. Mossburg | Allan Radaic | Katherine E. Woo | Pallavi Jonnalagadda | Yvonne L. Kapila | Paul L. Bollyky | David P. Cormode
Source: Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology (review, 2024-05-01)
Field: Materials Science — Electronic, Optical and Magnetic Materials

A review of recent advances in the use of complex metal nanostructures for biomedical applications from diagnosis to treatment Complex metal nanostructures represent an exceptional category of materials characterized by distinct morphologies and physicochemical properties. Nanostructures with shape anisotropies, such as nanorods, nanostars, nanocages, and nanoprisms, are particularly appealing due to their tunable surface plasmon resonances, controllable surface chemistries, and effective targeting capabilities. These complex nanostructures can absorb light in the near-infrared, enabling noteworthy applications in nanomedicine, molecular imaging, and biology. The engineering of targeting abilities through surface modifications involving ligands, antibodies, peptides, and other agents potentiates their effects. Recent years have witnessed the development of innovative structures with diverse compositions, expanding their applications in biomedicine. These applications encompass targeted imaging, surface-enhanced Raman spectroscopy, near-infrared II imaging, catalytic therapy, photothermal therapy, and cancer treatment. This review seeks to provide the nanomedicine community with a thorough and informative overview of the evolving landscape of complex metal nanoparticle research, with a specific emphasis on their roles in imaging, cancer therapy, infectious diseases, and biofilm treatment. This article is categorized under: Diagnostic Tools > In Vivo Nanodiagnostics and Imaging Therapeutic Approaches and Drug Discovery > Nanomedicine for Infectious Disease Diagnostic Tools > Diagnostic Nanodevices. Nanotechnology ; Materials science ; Computer science ; Medicine Gold and Silver Nanoparticles Synthesis and Applications ; Nanoplatforms for cancer theranostics ; Nanoparticle-Based Drug Delivery