jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Tobias Theiss | Guzel Musabirova | Luca Gerhards | I. S. Anisimova | Ben G. E. Zoller | Thi Ngoc Ha Nguyen | Dmitry Denisov | Anton J.M. Schmidt | Sabrina Panter | Stefan Weber | Christoph Tegenkamp | Ilia A. Solov’yov | Jörg Matysik | Tanja Gulder
Source: Angewandte Chemie International Edition (article, 2025-08-05)
Field: Materials Science — Materials Chemistry

Distance‐Dependence of Photo‐CIDNP in Biomimetic Tryptophan–Flavin Diads Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are essential tools in natural and life sciences, but their low sensitivity often hampers their applicability. Photochemically induced dynamic nuclear polarization (photo-CIDNP) offers a versatile and mild method to overcome this limitation. Here, we report on structure-photo-CIDNP relationship studies in liquid-state NMR utilizing a holistic approach. We synthesized biomimetic tryptophan-flavin diads with varying linker lengths composed of conformationally rigid oligoproline units. The predominant polyproline II (PPII) helical structure ensures consistent donor-acceptor distances. Photo-CIDNP NMR experiments revealed significant hyperpolarization effects, particularly in diads with six proline units, mimicking the spatial arrangement found in natural photoactive proteins. Our findings highlight the potential of these biomimetic diads to enhance nuclear hyperpolarization in NMR spectroscopy. This work provides valuable insights into the design of diads for efficient photo-CIDNP generation, paving the way for advanced studies in modern NMR and bio-MRI. CIDNP ; Hyperpolarization (physics) ; Chemistry ; Nuclear magnetic resonance spectroscopy ; Solid-state nuclear magnetic resonance ; Polyproline helix ; Photochemistry ; Nuclear magnetic resonance ; Polarization (electrochemistry) ; Stereochemistry ; Physics ; Physical chemistry Photochromic and Fluorescence Chemistry ; bioluminescence and chemiluminescence research ; Photoreceptor and optogenetics research
Authors: Xunjie Lin | Yunfei Luo | Dongxian Li | Zhe Tang | Yue Li | Kaipeng Liu | Qingguo Du | Changtao Wang | Weisheng Yue
Source: Nanophotonics (article, 2025-09-01)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Dual‐band high‐Q quasi‐BIC metasurface for refractive index sensing Sensitive and miniaturized optical sensing device is highly desirable in various biosensing applications. This study reports a dual-band, high-quality-factor (<i>Q</i> factor) quasi-bound states in the continuum (quasi-BIC) metasurface for refractive index sensing, operating across the visible (700-800 nm) and near-infrared (950-1,000 nm) spectral ranges. By incorporating asymmetric dual nanoholes into an all-dielectric silicon metasurface, symmetry-protected BIC modes are transformed into quasi-BIC, resulting in two distinct Fano-type resonance peaks. Numerical simulations and experimental validations demonstrate that precise control over resonance wavelengths and quality factors can be achieved by adjusting the nanohole radius and positional offsets (Δ), yielding a theoretical <i>Q</i>-factor of 2,250. The sensor exhibits a refractive index sensitivity of 151.6 nm/RIU for the visible band (Q-BIC I) and 61.1 nm/RIU for the near-infrared band (Q-BIC II), with a signal-to-noise ratio (SNR) of 285, significantly outperforming existing nanohole-based biosensors. Fabricated using CMOS-compatible processes, the device employs cost-effective visible-light detectors, eliminating the need for specialized infrared materials. This work advances the development of high-sensitivity, miniaturized refractive index sensing platforms, offering promising applications in biomedical diagnostics and environmental monitoring. Refractive index ; Sensitivity (control systems) ; Wavelength ; Silicon ; Resonance (particle physics) ; Multi-band device ; Infrared ; Biosensor Metamaterials and Metasurfaces Applications ; Plasmonic and Surface Plasmon Research ; Advanced Antenna and Metasurface Technologies
Authors: Yuying Yan | Weifeng Lyu | Hongwei Yu | Wenfeng Lv | Keqiang Wei | Linqin Jiang
Source: Molecules (article, 2025-10-15)
Field: Materials Science — Materials Chemistry

Advances in Synergistic Corrosion Mechanisms of and Management Strategies for Impurity Gases During Supercritical CO2 Pipeline Transportation Supercritical CO<sub>2</sub> (sCO<sub>2</sub>) pipeline transport is a critical link for the large-scale implementation of Carbon Capture, Utilization, and Storage (CCUS) technology, yet its safety is severely challenged by residual impurity gases (e.g., H<sub>2</sub>O, O<sub>2</sub>, SO<sub>2</sub>, H<sub>2</sub>S, and NO<sub>2</sub>) from the capture process. This review systematically consolidates recent research advances, with the key findings being the following. Firstly, it reveals that the nonlinear synergistic effects among impurities are the primary cause of uncontrolled corrosion, whose destructive impact far exceeds the simple sum of individual effects. Secondly, it delineates the specific roles and critical thresholds of different impurities within the corrosion chain reaction, providing a theoretical basis for targeted control. Consequently, engineering management must enforce strict impurity concentration thresholds integrated with material upgrades and dynamic operational optimization. Future research should focus on developing multi-impurity reaction kinetic models, elucidating long-term corrosion product layer evolution, and establishing standardized experimental systems. This review provides crucial theoretical support for establishing impurity control standards and optimizing anti-corrosion strategies for the safe transport of CO<sub>2</sub> in supercritical CCUS pipelines. Supercritical fluid ; Corrosion ; Impurity ; Pipeline transport ; Pipeline (software) ; Carbon capture and storage (timeline) Corrosion Behavior and Inhibition ; Hydrogen embrittlement and corrosion behaviors in metals ; Petroleum Processing and Analysis
Authors: Bowen Shen | Fei Zhou | Péter Nemes
Source: Angewandte Chemie International Edition (article, 2025-08-23)
Field: Chemistry — Spectroscopy

Real‐Time Eco–AI, Electrophoresis‐Correlative Data‐Dependent Acquisition with AI‐Based Data Processing Broadens Access to Single‐Cell Mass Spectrometry Proteomics Single-cell mass spectrometry (MS) offers unprecedented sensitivity for profiling cellular proteomes, yet widespread adoption is hindered by the cost of advanced instrumentation. Here, we broaden access to single-cell proteomics by combining capillary electrophoresis (CE), data-dependent acquisition (DDA) with electrophoresis-correlative (Eco) ion sorting, and artificial intelligence (AI)-assisted spectral deconvolution via CHIMERYS (Eco-AI). This "Real-Time Eco-AI" workflow was implemented on a custom-built CE platform coupled to a legacy hybrid quadrupole-orbitrap mass spectrometer (Q Exactive Plus). Despite slower scan speed, lower resolution, and inferior ion transmission efficiency, real-time Eco-DDA sampling and CHIMERYS processing enabled identification of up to ∼15 peptides per spectrum-performance on par with modern Orbitrap Fusion Lumos tribrid systems. From 1 ng of HeLa digest, 2142 proteins were identified, surpassing the 969 proteins detected on a contemporary nanoLC Orbitrap Fusion Lumos. Even from ∼250 pg (a single-cell equivalent), 1799 proteins were identified in <15 min of effective separation, raising a theoretical throughput of 48 samples per day. As proof of principle, Real-Time Eco-AI profiled 1524 proteins from single precursor cells (50-75 µm diameter) in Xenopus laevis blastulae, revealing proteome asymmetry during neural versus epidermal fate specification. These results establish Real-Time Eco-AI as a budget-conscious yet powerful strategy for single-cell proteomics using CE-MS. Proteomics ; Mass spectrometry ; Correlative ; Data acquisition ; Computer science ; Computational biology ; Chemistry ; Chromatography ; Biology ; Biochemistry Advanced Proteomics Techniques and Applications ; Single-cell and spatial transcriptomics ; Cell Image Analysis Techniques
Authors: Amira S. Gouda | Mamdouh R. Rezk | Ahmed M. Abdel‐Megied | Hoda M. Marzouk
Source: Royal Society Open Science (article, 2025-01-01)
Field: Materials Science — Materials Chemistry

Ultrasensitive turn-off fluorescent sensor for estimation of the new influenza antiviral prodrug baloxavir marboxil in its pharmaceutical formulation Carbon quantum dots (CQDs) are a recently developed class of fluorescent nanoparticles made from carbon. Co-doping with heteroatoms such as nitrogen and sulfur improved the properties and generated a high quantum yield. In the proposed study, we utilized a simple, cost-effective, single-stage hydrothermal approach to produce extreme photoluminescence co-doped, nitrogen and sulfur, CQDs (N,S-CODs). Thiosemicarbazide was used as a nitrogen and sulfur source, while citric acid was used as a carbon source to produce fluorescent probes. The prepared N,S-CQDs were subjected to extensive characterization. The generated N,S-CQDs yielded strong fluorescence emission at <i>λ</i> <sub>em</sub> 430.0 nm after excitation at <i>λ</i> <sub>ex</sub> 360.0 nm, with a relatively high quantum yield of 41.3% utilizing quinine sulfate as a reference fluorescent compound. These N,S-CQDs were applied as fluorescent nanosensors for the ultrasensitive spectrofluorimetric determination of baloxavir marboxil (BXM) directly without pre-derivatization for the first time. BXM effectively quenches the native fluorescence of N,S-CQDs. Considering the optimal conditions, the fluorescence intensity reduction of N,S-CQDs exhibited a 'turn-off' response to BXM at concentrations of 10.0-100.0 ng ml<sup>-1</sup>, with detection limits of 1.88 ng ml<sup>-1</sup> and quantitation limits of 5.69 ng ml<sup>-1</sup>, respectively. The proposed method determined BXM successfully in its tablet dosage form and further expanded to confirm the content uniformity of the tablet units in agreement with USP guidelines. Fluorescence ; Quantum yield ; Sulfur ; Carbon fibers ; Heteroatom ; Chemistry ; Carbon quantum dots ; Detection limit ; Yield (engineering) ; Nanoparticle ; Citric acid ; Analytical Chemistry (journal) ; Nuclear chemistry ; Materials science ; Photochemistry ; Chromatography ; Nanotechnology ; Organic chemistry Carbon and Quantum Dots Applications ; Advanced biosensing and bioanalysis techniques ; Electrochemical sensors and biosensors
Authors: Yasmeen G. Abou El‐Reash | Faisal K. Algethami | Abdullah N. Alotaibi | Mohamed A. Hashem | Marsa G. Wahba | Mohamed A. Ismail | Basem E. Keshta | Ahmad Hosseini–Bandegharaei
Source: Frontiers in Water (article, 2025-12-05)
Field: Chemistry — Analytical Chemistry

A simple mixed-micelle process for selective microextraction of trace Th(IV) from lanthanide matrices Prolonged exposure to thorium and its compounds can cause severe and irreversible damage to the bones and the kidneys, highlighting the need for its selective separation from other rare earth elements, particularly uranium. Traditional detection methods for Th(IV) are often time-consuming and costly. In this study, we present a simple and efficient mixed micelle-mediated microextraction method for Th(IV). Thorium was complexed with Solochrome Cyanine R (SCR) and extracted using Triton X-114 at 45 °C with KNO₃ and cetyltrimethylammonium bromide (CTAB) to enhance phase separation and extraction efficiency. The method achieved &amp;gt;95% extraction efficiency, a 100-fold preconcentration factor, and a detection limit of 0.8 ng mL −1 . Thorium was completely extracted at pH ≥ 3 in the presence of U(VI) and lanthanides (Nd(III), Ce(III), and Gd(III)). Recovery experiments with reference materials, freshwater, and synthetic mixtures confirmed the accuracy and applicability of the method. Extraction (chemistry) ; Thorium ; Lanthanide ; Detection limit ; Trace Amounts ; TRACE (psycholinguistics) ; Separation process ; Solid-phase microextraction Analytical chemistry methods development ; Radioactive element chemistry and processing ; Extraction and Separation Processes
Authors: Tatjana Ivaškienė | Greta Kaspute | Arūnas Ramanavičius | Urtė Samukaitė-Bubnienė
Source: Gels (review, 2025-04-04)
Field: Chemistry — Analytical Chemistry

Molecularly Imprinted Polymer Advanced Hydrogels as Tools for Gastrointestinal Diagnostics Gastroenterology faces significant challenges due to the global burden of gastrointestinal (GI) diseases, driven by socio-economic disparities and their wide-ranging impact on health and healthcare systems. Advances in molecularly imprinted polymers (MIPs) offer promising opportunities for developing non-invasive, cost-effective diagnostic tools that enhance the accuracy and accessibility of GI disease detection. This research explores the potential of MIP-based sensors in revolutionizing gastrointestinal diagnostics and improving early detection and disease management. Biomarkers are vital in diagnosing, monitoring, and personalizing disease treatment, particularly in gastroenterology, where advancements like MIPs offer highly selective and non-invasive diagnostic solutions. MIPs mimic natural recognition mechanisms, providing stability and sensitivity even in complex biological environments, making them ideal for early disease detection and real-time monitoring. Their integration with advanced technologies, including conducting polymers, enhances their functionality, enabling rapid, point-of-care diagnostics for gastrointestinal disorders. Despite regulatory approval and scalability challenges, ongoing innovations promise to revolutionize diagnostics and improve patient outcomes through precise approaches. Healthcare system ; Health care ; Disease ; Computer science ; Medicine ; Nanotechnology ; Pathology ; Materials science Analytical chemistry methods development ; Biosensors and Analytical Detection ; Analytical Chemistry and Chromatography
Authors: Mingzhi Jiang | Bo Li | Yinghao Zhao | Wenxuan Mo | Zhiyong Peng | Wanhua Wang | Feng Liao
Source: Advanced Functional Materials (article, 2025-07-06)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Superelastic Biomass‐Based Carbon Aerogels Reinforced by Vein‐Like Networks and Pillar Structures for Piezoresistive Sensing, High‐Temperature Applications, and Supercapacitors Abstract Biomass‐based carbon aerogels with tunable structures exhibit excellent compressibility and flexibility, serving as sustainable, cost‐effective materials for high‐performance piezoresistive sensors. However, achieving excellent integrated properties of superior fatigue resistance, ultra‐high compressibility, high sensitivity, low‐pressure detection limits, and wide linear sensing ranges remains a challenge. Herein, inspired by the leaf‐vein network structure and architectural pillar, a carbon aerogel with a “vein‐like network and pillar‐reinforced wavy layer structure” is developed. Benefiting from this structure, it enables exceptional fatigue resistance (96.7% stress retention and 99.1% height retention after 20000 compression cycles at 50% strain), which is second to none among the reported biomass‐based carbon aerogels. Meanwhile, its sensor integrates high linear sensitivity ( S = 59.70 kPa −1 at 0–100 Pa, S = 16.76 kPa −1 at 100–15000 Pa), a wide linear pressure range (0–15 kPa), an ultralow detection limit (0.186 Pa), and recoverable elasticity under extreme strain (99%), realizing the perfect performance of a piezoresistive sensor. Additionally, it exhibits excellent thermal insulation, flame resistance, and superior supercapacitive performance. These synergistic properties further enhance its applicability in motion monitoring, sensor units of aerospace, supercapacitors, and self‐powered wearable devices. Materials science ; Supercapacitor ; Piezoresistive effect ; Pillar ; Biomass (ecology) ; Composite material ; Carbon fibers ; Nanotechnology ; Electrode ; Capacitance ; Mechanical engineering ; Composite number Supercapacitor Materials and Fabrication ; Advanced Sensor and Energy Harvesting Materials ; Aerogels and thermal insulation
Authors: Cecília Roratto Köhn | Lilia da Rosa Fagundes | Simone Hickmann Flôres | Alessandro de Oliveira Rios
Source: Packaging Technology and Science (article, 2025-04-29)
Field: Materials Science — Biomaterials

Biodegradable Sodium Alginate Films Enriched With Oils—A Review ABSTRACT Environmental pollution from plastic polymers is a global concern that harms ecosystems and human health. Developing biodegradable sodium alginate films, derived from seaweed, emerges as a promising solution to mitigate these impacts. The sodium alginate is biodegradable, non‐toxic and has excellent film‐forming properties, making it a substitute for conventional packaging. Incorporating oils into alginate films significantly improves their functional properties, as they are rich in bioactive compounds, such as antioxidants, which increase resistance to oxidation, prolonging the shelf life of packaged products. Essential oils provide specific antimicrobial and antioxidant benefits due to their bioactive volatile compounds, such as terpenes and phenols, which offer additional protection against microbial degradation. Additionally, adding oils increases flexibility, reducing the brittleness of the films and enhancing their elasticity. Oils also improve the films' barrier properties against water vapour and oxygen, preserving food quality and freshness. The presence of oils in alginate films also adds sensory and antimicrobial benefits, resulting in films with controlled release of compounds, offering a multifunctional approach to food preservation. This combination of properties enhances the functionality of the films, making them a sustainable and efficient alternative to conventional plastics. This review highlights biodegradable sodium alginate films with added oils as an environmentally friendly alternative to reduce environmental pollution and improve food preservation, providing additional functional benefits. This approach represents a significant advance in the search for sustainable and effective options, aligning with the goals of sustainability, consumer appreciation and environmental protection. Sodium alginate ; Food packaging ; Environmentally friendly ; Environmental pollution ; Materials science ; Antimicrobial ; Biochemical engineering ; Chemistry ; Food science ; Environmental science ; Organic chemistry ; Sodium ; Environmental protection Nanocomposite Films for Food Packaging ; Microplastics and Plastic Pollution ; biodegradable polymer synthesis and properties
Authors: Abhiram Kumar | Chhavi Dhiman | Madhaw Kumar | N. Kannappan | Deepak Kumar | Manish K. Chourasia | Kumar Pranav Narayan
Source: Journal of Applied Pharmaceutical Science (article, 2025-01-01)
Field: Chemistry — Analytical Chemistry

Development of a quality by design based hybrid RP-HPLC method for Glimepiride: Bioanalytical and industrial applications In this study, we present a hybrid analytical method for the quantification of glimepiride (GLP) from blood plasma and pharmaceutical formulations. Shimadzu HPLC (Model SIL 20 AC HT), a photodiode array detector, and a Phenomenex C18 column (150 × 4.6 mm, 4 μm) were used for method development. A further quality by design (QbD) surface optimization model was applied, and the best-optimized method with chromatographic conditions, such as an injection volume of 15 μl, a column oven temperature of 40°C, a sample cooler temperature of 15°C ± 1°C, a run time of 5 minutes, and a flow rate of 0.8 ml/minute with a mobile phase composition (acetate buffer: acetonitrile, 40:60 ratio), was identified. Finally, the method was validated, and GLP was quantified from various pharmaceutical dosage forms and blood plasma. The results were observed in subsequent laboratories in diluent media and mouse plasma with limits of detection of 0.066 μg/ml and 0.193 μg/ml, respectively, followed by limits of quantification of 0.199 μg/ml and 0.583 μg/ml, respectively. Subsequently, linearity (r2) was observed at 0.999 for both samples. The AUC was 228 ± 2 nm, and the retention time (RT) was 2.8 ± 0.28 minutes. The plasma matrix effect was calculated to be 81.9%. The research findings revealed that the proposed analytical method could be used for both analytical and bioanalytical applications at the industrial scale. Bioanalysis ; Glimepiride ; Quality by Design ; Computer science ; Quality (philosophy) ; Chromatography ; Biochemical engineering ; Process engineering ; Chemistry ; Engineering ; Biotechnology ; Biology ; Operations management ; Physics Analytical Methods in Pharmaceuticals ; Analytical Chemistry and Chromatography ; Crystallization and Solubility Studies
Authors: Cristina Campano | Virginia Rivero‐Buceta | Ana M. Hernández‐Arriaga | Maria‐Tsampika Manoli | M. Auxiliadora Prieto
Source: International Journal of Biological Macromolecules (review, 2025-08-08)
Field: Materials Science — Biomaterials

Pushing the limits of bacterial cellulose for biomedicine: a review Biomedicine ; Nanotechnology ; Tissue engineering ; Biochemical engineering ; Computer science ; Biomaterial ; Biocompatibility ; Surface modification ; Materials science ; Engineering ; Biomedical engineering ; Bioinformatics ; Biology ; Mechanical engineering Advanced Cellulose Research Studies ; Electrospun Nanofibers in Biomedical Applications ; Cancer Research and Treatments
Authors: Chao Zhong | Kuibao Yu | Yuan Qie | Yongshen Yu | Yongyi Lu | Ge Deng | Tailiang Guo | Hailong Hu | Fushan Li
Source: Advanced Functional Materials (article, 2025-06-25)
Field: Materials Science — Materials Chemistry

Ultrahigh‐Resolution Full‐Color Quantum Dot LEDs Based on Region‐Selective Interfacial Self‐Assembly Abstract Colloidal quantum dots (QDs) have shown great promise in the development of high‐resolution displays for near‐eye visual communication with the outside world. However, achieving full‐color high‐precision assembly of QDs at the nanoscale remains a critical challenge. This study proposes a novel strategy for the region‐selective assembly of QDs for achieving ultra‐high‐resolution light‐emitting devices. This approach leverages interface‐assembled ultrathin surface microstructures to create specific wettability patterns, guiding the selective assembly of QDs on their surfaces. Ultimately, an ultra‐high‐resolution 36 599 pixels per inch (PPI) light‐emitting device is successfully realized, with a record‐high external quantum efficiency (EQE) of 18.74%. The addition of a molecular microstructure enhances the fidelity of the assembled QDs pattern, providing nearly a two‐fold increase in contrast ratio while effectively suppressing device leakage current. Additionally, the assembly process is compatible with photo‐crosslinking technology, resulting in a full‐color light‐emitting device with an EQE of 11.01%. Our strategy paves a simple and effective way for advancements in high‐performance nano‐display technology. Materials science ; Quantum dot ; Light-emitting diode ; Self-assembly ; Optoelectronics ; Resolution (logic) ; Full color ; Nanotechnology Quantum Dots Synthesis And Properties ; Photonic Crystals and Applications ; ZnO doping and properties
Authors: Ying Zhang | Jiannong Wang | Xiuhong Wu | Rui Chang | Hong Luo | Juan Yang | Quan Wu | Ze Xu | Yingfu Zhong
Source: Frontiers in Chemistry (article, 2025-09-08)
Field: Materials Science — Materials Chemistry

Synthesis of carbon dots as an antibacterial and antioxidant agent This work presents a cost-effective and eco-friendly approach to producing carbon dots with dual functionality as both antibacterial and antioxidant agents. Antioxidant ; Carbon fibers ; Antibacterial activity ; Carbon quantum dots ; Dual (grammatical number) Carbon and Quantum Dots Applications ; Electrochemical sensors and biosensors ; Advanced Nanomaterials in Catalysis