jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Xiaowei Xu | Ning Qian | Hanbin Chen | Jie Pang
Source: Process Biochemistry (article, 2025-05-28)
Field: Materials Science — Biomaterials

Fiber composite hydrogels: Advances in food preservation and biomedical applications Self-healing hydrogels ; Fiber ; Composite number ; Materials science ; Composite material ; Polymer chemistry Electrospun Nanofibers in Biomedical Applications ; Hydrogels: synthesis, properties, applications ; Advanced Sensor and Energy Harvesting Materials
Authors: Xihong Lu | Liqing Yang | Lan Ma | Jiangfeng Wu | Hongbing Zhang | Ying Wang
Source: Journal of Liposome Research (review, 2025-09-21)
Field: Materials Science — Biomaterials

Liposome stability: multifactorial regulation and optimization strategies in in vivo delivery As an essential carrier for drug delivery systems, the stability of liposomes directly influences the efficiency and safety of drug delivery. In the complex and challenging process of in vivo delivery, the stability of liposomes is affected by both their inherent properties and external environmental factors. This paper first introduces the in vivo journey of liposomes, encompassing blood circulation, tissue distribution, metabolism, and excretion. It then summarizes the biological factors affecting liposome stability, including immune recognition, protein-lipid interactions, enzyme-catalyzed degradation, and physiological changes. Additionally, the paper explores effective strategies to enhance liposome stability, such as optimizing lipid composition and surface modification. Finally, it discusses future research directions and existing challenges, focusing on AI-assisted liposome development, and the development of biocompatible materials. The study emphasizes the critical factors affecting liposome stability, uncovers current limitations, and highlights future potential in this field, providing a theoretical foundation and practical guidance for the design and application of liposomes. Liposome ; In vivo ; Drug delivery ; Biocompatible material ; Drug ; Drug carrier Nanoparticle-Based Drug Delivery ; RNA Interference and Gene Delivery ; Lipid Membrane Structure and Behavior
Authors: Sunayana Vikhe | Parmeshwar M. Pathade | Bhavana R Tambe
Source: Medical and Pharmaceutical Journal (article, 2025-01-01)
Field: Materials Science — Biomaterials

Stimuli-Responsive Nanocarriers: Revolutionizing Site-Specific Drug Release Smart nano-carriers for drug delivery are opening new frontiers as they respond to stimuli inside the human body and/or from outside as well, with the scope to release the drug at the desired time and place with responsive to stimuli like pH, temperature, enzymes, redox potential, light, ultrasound, and/or magnetic fields. Pathological microenvironments such as, acidic pH in tumor tissues or high glutathione in cancer cells are used by these smart systems to release the drug at a targeted site thus reducing general side effects and improving the therapeutic index. Effective scenarios encompass pH-sensitive disassembly, heating and cooling changes, enzyme catalysed breakage, and redox sensitive bond cleavage in numerous diseases such as cancer, neurological disorders, cardiovascular diseases, and infections. Substances like polymers, lipids and inorganic nanoparticles improve the stability, targeting ability and sensitivity of these carriers. Ligand conjugation enhancements also enhance specificity due to increased receptor overexpression and better uptake and localization of the surface-modified nanoparticles. In the case of oncology, these systems accurately target the tumor microenvironments and in neurology the systems help to cross the blood-brain barrier to exert the drug’s action. Additional areas can also be found in infectious diseases for which controlled release of antibiotics as well as antiviral agents enhances localized therapy and minimizes emergence of resistance patterns. Even though there are some issues limit the development of these nanocarriers such biocompatibility, scalability, and regulatory approval, precision medicine still looks forward to the existence of these nanocarriers. The improvements for the future are the following: the integration of multifunctional characteristics, the usage of artificial intelligence in the designing process, and the long-term safety to increase the clinical relevance and the applicability of the material to the environment. Stimuli-responsive nanocarriers are therefore a step up in the realization of efficient and individualised therapeutic results. Nanocarriers ; Drug ; Drug delivery ; Targeted drug delivery ; Chemistry ; Nanotechnology ; Pharmacology ; Medicine ; Materials science Nanoparticle-Based Drug Delivery ; Graphene and Nanomaterials Applications
Authors: Dandi Bachtiar | Zulfan Zulfan | Al Munawir
Source: Jurnal Mekanova Mekanikal Inovasi dan Teknologi (review, 2025-05-31)
Field: Materials Science — Polymers and Plastics

Hybrid Natural Fibre Polymer Composites: A Comprehensive Review Hybrid natural fibre polymer composites (HNFPCs) have emerged as an innovative and sustainable alternative to conventional fibre-reinforced composites, driven by the need for eco-friendly, lightweight, and high-performance materials. This review presents a comprehensive analysis of recent advancements in HNFPCs, focusing on material constituents, fabrication techniques, resulting properties, and industrial applications. Various hybrid systems, including natural–natural and natural–synthetic fibre combinations, are explored for their synergistic potential in improving mechanical strength, thermal stability, and moisture resistance. The influence of surface modification methods and processing parameters on the interfacial bonding and durability of composites is critically discussed. A comparative evaluation of key physical and mechanical properties is provided using recent literature (2020–2024), highlighting performance trends across different hybrid configurations. Applications in automotive, aerospace, construction, marine, and consumer product sectors demonstrate the industrial relevance of HNFPCs, with an emphasis on sustainability and regulatory compliance. Despite their promise, challenges remain in property variability, limited thermal performance, and recyclability. Future perspectives suggest that integrating bio-based matrices, advanced treatments, and data-driven design will be essential in advancing the next generation of multifunctional, green composites. This review aims to provide a valuable resource for researchers and industry stakeholders seeking to optimize the development and deployment of HNFPCs for structural and semi-structural applications. Automotive industry ; Durability ; Materials science ; Sustainability ; Aerospace ; Environmentally friendly ; Biochemical engineering ; Composite material ; Process engineering ; Computer science ; Construction engineering ; Engineering Natural Fiber Reinforced Composites ; Innovations in Concrete and Construction Materials ; Additive Manufacturing and 3D Printing Technologies
Authors: Najam Aziz | Norfadzlia Mohd Yusof | Yogan Jaya Kumar | Siti Haryanti Hj Hairol Anuar | Farhad Soleimanian Gharehchopogh
Source: Journal of Physics Conference Series (article, 2025-04-01)
Field: Chemistry — Analytical Chemistry

Enhancing QSAR Model Accuracy for Biodegradability Prediction Using Chaotic Adaptive Binary Manta Ray Foraging Optimization Abstract Choosing descriptors is a crucial aspect of improving QSAR (Quantitative Structure-Activity Relationship) models, especially when it comes to precisely forecasting chemical biodegradability. As cheminformatics advances, the handling of large molecular datasets introduces challenges due to the high dimensionality created by numerous molecular descriptors. This study presents the Chaotic Adaptive Somersault Factor Binary Manta Ray Foraging Optimization (CASF-BMRFO) algorithm, designed to optimize descriptor selection and boost QSAR model performance. By integrating innovative techniques such as the Piecewise map and a nonlinear time-varying Sigmoid transfer function, CASF-BMRFO achieves improved accuracy and efficiency, particularly for complex biodegradability datasets. The algorithms test on high-dimensional QSAR biodegradation data, the CASF-BMRFO6 variant showed substantial performance gains, achieving faster convergence while reducing selected descriptors by 75%. Additionally, it enhanced prediction accuracy by 11.59%, demonstrating its efficacy in selecting relevant descriptors and its potential for broader application in other classification tasks. These findings highlight CASF-BMRFO6’s effectiveness in feature selection and encourage further exploration of its adaptability across diverse data-driven domains. Foraging ; Binary number ; Chaotic ; Computer science ; Quantitative structure–activity relationship ; Artificial intelligence ; Machine learning ; Mathematics ; Ecology ; Biology Spectroscopy and Chemometric Analyses ; Industrial Vision Systems and Defect Detection ; Cell Image Analysis Techniques
Authors: Yuxiang Bu | Yanxin Wang | H. T. Wu | Hanwen Wang | Bin Wang | Yanpu Yang | Linjun Huang | Jianguo Tang
Source: Materials Today Chemistry (article, 2025-08-27)
Field: Materials Science — Materials Chemistry

Recent advances in flexible piezoresistive pressure sensors based on MXene materials Piezoresistive effect ; Materials science ; Pressure sensor ; Nanotechnology ; Composite material ; Mechanical engineering ; Engineering MXene and MAX Phase Materials ; Advanced Sensor and Energy Harvesting Materials ; Advanced Memory and Neural Computing
Authors: Karuppiah Nagaraj
Source: Pharmaceutical Development and Technology (article, 2025-11-25)
Field: Chemistry — Organic Chemistry

Surfactant-based drug delivery strategies for HIV/AIDS therapy: advances in formulation and clinical translation The present paper provides a detailed overview of surfactants' function in HIV/AIDS therapy, with a focus on medication administration, direct antiviral mechanisms, and microbicide formulations. The use of surfactant-based nanotechnology into antiretroviral therapy has resulted in the development of liposomes, polymeric micelles, nanoemulsions, and surfactant-modified biomaterials that provide controlled release and increased bioavailability of antiretrovirals. Furthermore, many surfactants have inherent antiviral activity, which disrupts the viral lipid envelope, inhibits viral replication, and prevents HIV from entering host cells. The paper also explores the potential of surfactant-based biosensors for HIV diagnostics, emphasizing their role in improving sensitivity and selectivity and recent progress in formulation design using surfactants such as sodium lauryl sulfate, poloxamers, and biosurfactants, emphasizing their safety, biocompatibility, and clinical potential. Key challenges including scalability, environmental impact, and user acceptability are discussed alongside emerging AI-driven approaches for personalized nanomedicine. Surfactant toxicity and limited biocompatibility remain key barriers. Developing safer, more effective surfactants is essential for future clinical progress. Drug delivery ; Microbicide ; Biocompatibility ; Human immunodeficiency virus (HIV) ; Bioavailability ; Drug ; Biocompatible material ; Targeted drug delivery Polydiacetylene-based materials and applications ; Surfactants and Colloidal Systems ; Advancements in Transdermal Drug Delivery
Authors: Gopinathan Janarthanan | Rashik Chand | Sanjairaj Vijayavenkataraman
Source: Progress in Biomedical Engineering (review, 2025-08-04)
Field: Materials Science — Materials Chemistry

Recent Advances in Non-Planar Collectors for Melt Electrowriting (MEW): Creating Physiologically Relevant Scaffold Structures for Tissue Engineering Melt electrowriting (MEW) is an advanced additive manufacturing technique that offers unprecedented microscale control over polymer fiber deposition for tissue engineering applications. This review focuses on recent advancements in MEW technology beyond flat collectors to non-planar, anatomically relevant structures. Such non-planar MEW is enabled by maintaining stable electric field control through a consistent nozzle-to-collector distance, using custom 3D-printed insulating collectors, and multi-axis MEW setup. These advancements allow accurate fiber patterning on curved surfaces and make non-planar MEW feasible for complex scaffold geometries. In parallel, the integration of MEW with complementary fabrication methods (such as fused deposition modeling, electrospinning, and bioprinting) has emerged, permitting the fabrication of intricate, multi-functional scaffolds that closely mimic natural tissue architectures. Automated, multi-parameter process control strategies, through real-time feedback systems incorporating machine vision and artificial intelligence, further improve fiber deposition accuracy and scaffold reproducibility. This review highlights both the key breakthroughs and remaining challenges in non-planar MEW, underscoring the technology's transformative potential in tissue engineering to create highly customized, biomimetic, and physiologically relevant tissue structures. Planar ; Scaffold ; Microscale chemistry ; Computer science ; Nanotechnology ; Fabrication ; Tissue engineering ; Electrospinning ; Materials science ; Deposition (geology) ; Fiber ; Biomedical engineering ; Polymer ; Engineering Anodic Oxide Films and Nanostructures ; Advanced Memory and Neural Computing ; Electrodeposition and Electroless Coatings
Authors: Bixia Zhou | Yongqin Su | Bin Wu | Bingbing Gao | Bingfang He | Chwee Teck Lim
Source: Advanced Functional Materials (article, 2025-07-16)
Field: Materials Science — Biomaterials

Amorphous Region Modifications Enhance Genetically Engineered Spider Silk for Advanced Wearable Applications Abstract Natural spider silk possesses exceptional properties and has been driving the rapid development of genetically engineered spider silk proteins (spidroins) in the past few decades. Existing sequence designs focus primarily on mimicking crystalline regions. Here, an amorphous region modification strategy for the programmable genetic biosynthesis of spidroins (ARMs) with enhanced properties for wearable applications is presented for the first time. Polar acid–base modifications in the spidroin's amorphous region enable efficient expression and straightforward purification while also imparting spidroins with facile molding properties. Additionally, salt bonds formed by acid–base amino acid pairs strengthen intermolecular interactions, driving self‐assembly and reinforcing β‐sheet crystal structures, which significantly increase the mechanical strength (tenfold compared to controls). Electrostatic interactions arising from acid–base amino acids enhance the electrostatic properties of spidroins. The performance of ARM‐based microneedle wearables in triboelectric nanogenerators and wound patches is demonstrated. This modification strategy can be applied broadly to next‐generation spider silk designs, expanding their applications in human–machine interactions, organ‐on‐chips, and artificial intelligence robotics. Spider silk ; Materials science ; SILK ; Nanotechnology ; Biophysics ; Biology ; Composite material Silk-based biomaterials and applications ; Biochemical and Structural Characterization ; Antimicrobial Peptides and Activities
Authors: Luyao Ma | Bowen Zhang | Xiaomei Liu | Shengwei Gao | S.K. Kong | Yanfen Li | Ruihua Wang | Meifeng Li | Xiao‐Yuan Mao | Yuhong Li | Yang Luo | Liang Li | Chunxiao Lv | Yühong Huang
Source: Frontiers in Pharmacology (review, 2025-10-03)
Field: Materials Science — Biomaterials

Nanotechnology-driven synergy in cardio-oncology: enhancing tumor suppression and reducing cardiotoxicity The integration of nanotechnology into oncology has profoundly reshaped cancer treatment, enabling drug delivery systems with remarkable precision, enhancing antitumor efficacy, and simultaneously addressing major challenges such as cardiotoxicity, one of the most prevalent and serious adverse effects of conventional chemotherapy. This review systematically examines the dual role of nanotechnology, highlighting its capacity to enhance the therapeutic effectiveness of anticancer treatments while concurrently mitigating cardiotoxic side effects. The discussion centers on a broad spectrum of nanocarrier platforms, such as liposome-based, polymeric nanocarriers, and inorganic nanocarriers organized according to their structural features and therapeutic benefits, thereby enabling a systematic comparison with conventional drug delivery strategies. By improving drug bioavailability, enabling controlled release, and achieving precise tumor-specific targeting, these nanocarrier systems enhance antitumor efficacy while concurrently reducing collateral damage to healthy tissues. Moreover, recent preclinical and clinical studies were summarized to demonstrate substantial advances in this interdisciplinary field, while also identifying persistent challenges that remain to be addressed. Finally, the review explores future directions, with particular emphasis on the integration of artificial intelligence to optimize nanocarrier design and the promise of personalized nanomedicine in transforming cancer care. Overall, this work provides a critical foundation for advancing next-generation, patient-tailored cancer therapies. Nanocarriers ; Cardiotoxicity ; Nanomedicine ; Drug delivery ; Collateral damage ; Cancer ; Drug ; Broad spectrum Nanoparticle-Based Drug Delivery ; Nanoplatforms for cancer theranostics ; Carbon Nanotubes in Composites
Authors: Stephen Sunday Emmanuel | Ademidun Adeola Adesibikan | Festus Smith Oghenegaga Afigo | Miracle Adeyeni Ajayi | Gloria Onome Achurefe | ‏Abdullah K. Alanazi | Ebenezer Temiloluwa Abimbola | Olumide James Oluwole | Christopher Olusola Olawoyin
Source: Journal of the Chinese Chemical Society (article, 2025-10-02)
Field: Chemistry — Analytical Chemistry

Photocatalytic degradation‐oriented technology using nano‐architecture materials for the remediation of harmful food dye pollutants: A review Abstract Photocatalytic degradation using nanoarchitecture materials remains a frontline technique for the remediation of aquatic pollutants, including food dyes, a crucial ingredient contributing positively to the food industry/production, while polluting the aquatic bodies. This paper aimed to review the remediation of food dye pollutants through photocatalytic degradation‐oriented technology. Beyond evaluating the photocatalytic degradation performance of various nanomaterials, this study takes advantage of radical scavengers/electron trapping to elucidate the food dye photocatalytic degradation mechanism as part of the study's novelty. Another novelty of this work is in recyclability and real‐life application studies, which are often neglected in many other reviews, and this was explored in this work to establish the industrial applicability/eco‐economic benefits of nanomaterials. Notably, composite nanomaterials were found to be more efficient than the non‐composites. Findings also revealed that, on average, various nanomaterials have an optimum photocatalytic degradation capacity of &gt;75% for various food dyes and can be reused 2–10X while sustaining &gt;70% of the original efficiency. The electron trapping analysis further showed that •OH and •O 2 are the leading radicals responsible for photocatalytic degradation activities. The use of artificial intelligence for better photocatalytic degradation mechanism interpretation/probing of radicals' participation is found to be an interesting area for future research. Photocatalysis ; Degradation (telecommunications) ; Nanomaterials ; Environmental remediation ; Food industry ; Groundwater remediation Dye analysis and toxicity ; Advanced Nanomaterials in Catalysis ; Water Quality Monitoring and Analysis
Authors: Miguta Faustine Ngulimi | Kamal Asghar | Sion Kim | Bum Kyoung Seo | Changhyun Roh
Source: Journal of Hazardous Materials Advances (article, 2025-11-01)
Field: Materials Science — Materials Chemistry

The radioactive waste management - State of the art and emerging technologies • Trends for treatment of radioactive wastes are discussed. • Methods and trends for immobilization of radioactive wastes are highlighted. • Characterization techniques for immobilized wastes forms are illustrated. • Detection mechanisms for radioactive chemical transformation are discussed. • Future challenges and scopes of radioactive wastes are elucidated. The sustainable management of radioactive waste remains a critical challenge amid the global expansion of nuclear energy. Although nuclear power offers a reliable and low carbon energy source, its radioactive byproducts, if inadequately managed, pose significant environmental and public health risks. This review provides an integrated assessment of current and emerging strategies for radioactive waste management, encompassing waste minimization, treatment, immobilization, and characterization. Emphasis is placed on the hierarchical framework of waste management, which prioritizes reduction, recycling, and reuse over final disposal. The paper further examines recent advancements in waste characterization, including real-time monitoring, advanced imaging, and artificial intelligence, which together enhance spatial radionuclide mapping and predictive modeling of waste form behavior. Beyond technological innovation, the review underscores the importance of robust policy frameworks and active public engagement to ensure transparency, social acceptance, and regulatory coherence. By promoting adaptive, science based, and participatory approaches, the nuclear sector can advance safer and more sustainable pathways for radioactive waste management. Radioactive waste ; Nuclear power ; Reuse ; Nuclear decommissioning ; Sustainability ; SAFER ; Emerging technologies ; Waste disposal Nuclear materials and radiation effects ; Radioactive element chemistry and processing ; Radioactive contamination and transfer
Authors: Yitong Xie | Xin Guo | Daihui Zhang | Xiaoping Shen | Qingfeng Sun | Fuxiang Chu
Source: ACS Sustainable Chemistry & Engineering (article, 2025-06-07)
Field: Materials Science — Biomaterials

Life Cycle Assessment and Environmental Cost Evaluation of Biomimetic Cellulose-Enhanced Hydrogels Cellulose-based hydrogels, recognized for their exceptional strength and toughness, have become promising alternatives to petroleum-based functional materials in soft robotics and wearable devices applications. However, the current lack of a detailed understanding of its environmental characteristics and robust quantitative research poses significant challenges to the long-term, sustainable design of biomass materials. To address this research gap and avoid shifting environmental problems in biomass material design, this study developed a sustainable assessment model using life cycle assessment to quantify and identify the drivers of environmental implications in the biomimetic cellulose-enhanced hydrogel fabrication process. The results indicated that preparation of cellulose skeleton and acrylamide solution are the main contributors to environmental burdens, accounting for 68% and 29% of the overall environmental impact. The main driving indicators come from primary energy demand (PED), CO2, SO2, NOx, and NH3–N during raw material extraction and electricity consumption. The scenario analysis revealed that optimizing materials and energy inputs collaboratively can reduce environmental implications and costs by 72.9% and 88.7%, respectively. This life cycle thinking-based quantitative model provides both data-driven insights for the design of cellulose-based materials, avoiding the risk of environmental problem shifting and offering practical guidance for advancing the sustainable development of biomass-derived functional materials. Cellulose ; Self-healing hydrogels ; Life-cycle assessment ; Chemistry ; Chemical engineering ; Materials science ; Nanotechnology ; Organic chemistry ; Engineering ; Production (economics) Advanced Cellulose Research Studies ; biodegradable polymer synthesis and properties ; Nanocomposite Films for Food Packaging