jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Virginia Cazzagon | Patrizia Pfohl | Bastien Pellegrin | Hervé Fontaine | Delphine Tissier | Arrate Huegun | Valeria Berner | Carl‐Christoph Höhne | Sébastien Artous | Socorro Vázquez‐Campos | Camilla Delpivo
Source: Preprints.org (preprint, 2025-12-09)
Field: Materials Science — Polymers and Plastics

Release Assessment Methodology for Safe Sustainable and Recyclable by-Design Practices for Plastics: The Epoxy-Resin Composite Case Study The development of new materials that are inherently safe and sustainable has become a critical objective in the context of the green transition. This challenge is especially significant for plastics, which often contain complex mixtures of chemicals that may be released during various stages of their life cycle and that can pose risks to human health and the environment. Within this context, the Safe and Sustainable by Design (SSbD) framework was followed to support the design of an innovative epoxy-vitrimer composite that integrates non-releasable fire-retardant functionalities, aiming to produce safer, sustainable, and recyclable materials suitable for railway applications. A simple methodology was developed to identify release hotspots potentially affecting workers, consumers, and environmental species and organisms. Based on this, experimental simulations were conducted to evaluate the release of materials such as flame retardants, non-intentionally added substances, and microplastics at hotspots and to compare release profiles between a benchmark material and an SSbD alternative. The results demonstrate that the newly developed recyclable and less hazardous composites can also reduce material release under weathering and abrasion conditions. Microplastics ; Life-cycle assessment ; Context (archaeology) ; Identification (biology) ; Human health ; Sustainability ; Benchmark (surveying) Flame retardant materials and properties ; Polymer Science and PVC ; Fire dynamics and safety research
Authors: Anatoliy Danylkovych | Victor Lishchuk
Source: Technology audit and production reserves (article, 2025-06-06)
Field: Materials Science — General Materials Science

Development of a composition for footwear using secondary recycled materials The object of this study is the process of forming a coating on a chromium-tanned split leather semi-finished product. The study is aimed at developing an optimal formulation of a finishing composition for the production of footwear upper leather. A technology has been developed for forming a decorative coating on chromium-tanned split hides from pigs and heavy cattle. The composition of the finishing formulation was determined through computer modeling and multiparameter optimization using Harrington’s desirability function. Based on the analysis of the physico-mechanical properties of the resulting monolithic films, the qualitative composition of the film-forming finishing composition was established. Computer-aided modeling of the “composition – property” system for a three-component formulation, using the Scheffé mathematical model, enabled the derivation of analytical relationships between the physico-mechanical properties of the finishing composition and its constituents. The optimal composition was determined at the maximum values of the desirability function and physico-mechanical parameters through multiparameter optimization. The leather produced using the optimal composition was tested under industrial conditions and complies with DSTU 2726-94 and DSTU 3115-95, for upper footwear leather and leather for garment production, respectively. The use of a highly porous chromium-tanned split leather semi-product derived from pig hides ensures the production of high-quality, elastic upper leather. The developed finishing technology for split hides of pigs and heavy cattle demonstrates significant potential for use in the manufacture of everyday footwear. Composition (language) ; Waste management ; Metallurgy ; Environmental science ; Engineering ; Materials science ; Art Material Properties and Applications ; Textile materials and evaluations ; Photopolymerization techniques and applications
Authors: K. Prathyusha | P.M. Priya | Koppula Jaya Nissi | Kolluru V.A. Ramaiah | M. R. Reddy | M Krishna
Source: Journal of Pharmacognosy and Phytochemistry (article, 2025-11-01)
Field: Chemistry — Organic Chemistry

Phytochemical and antimicrobial screening of Crinum asiaticum extract of herbal hand wash tablets This study evaluates the phytochemical composition and antimicrobial activity of Crinum asiaticum leaf extract for developing herbal hand wash tablets. Ethanolic extraction followed by qualitative screening confirmed the presence of alkaloids, flavonoids, tannins, phenols, glycosides, and saponins. The extract was tested against E. coli, Bacillus subtilis, and Aspergillus niger using the agar well diffusion method, showing clear, concentration-dependent zones of inhibition. A herbal hand wash tablet was formulated using the extract and assessed for pH, appearance, foamability, viscosity, and skin irritation, all of which met acceptable standards. The formulation displayed strong antimicrobial action comparable to marketed products. Overall, Crinum asiaticum extract demonstrates promising potential as a natural and effective antimicrobial ingredient for herbal hand wash tablets. Antimicrobial ; Phytochemical ; Ingredient ; Aspergillus niger ; Agar diffusion test ; Agar Chemical synthesis and alkaloids ; Advanced Synthetic Organic Chemistry ; Plant and fungal interactions
Authors: E. M. Suleimen | А. Н. Трофимов | Gulnur K. Mamytbekova | Dilnaz Kurbanaliyeva | Burkitkan Akbay | Tursonjan Tokay
Source: Frontiers in Environmental Chemistry (article, 2025-10-01)
Field: Chemistry — Analytical Chemistry

Squalene recovery from Uzen oil field wastewater: a novel abiotic resource Squalene (C 30 H 50 ), a triterpene hydrocarbon, a critical precursor in the biosynthesis of cell membrane steroids, is enzymatically derived via squalene synthase in both prokaryotic and eukaryotic organisms. Its remarkable physicochemical properties and potent antioxidant characteristics underlie its extensive application across various sectors including nutraceuticals, pharmaceuticals, cosmetics, and fragrance industries. Historically, squalene has been predominantly sourced from shark liver oil and select plant oils. However, contemporary sustainable considerations have spurred pioneering investigations into unconventional reservoirs. This study reports, for the first time, the extraction of squalene from wastewater of Kazakhstan’s Uzen oil field, identifying an abiotic reservoir with significant scientific and industrial potential. In this study, wastewater samples from the Uzen oil field were collected, extracted, and the composition of dissolved volatile compounds in the extract was investigated using gas chromatography-mass spectrometry (GC-MS). Notably, the predominant constituents were hydrocarbons, which was expected. Intriguingly, the analysis also revealed substantial quantities of squalene–a natural biomarker of oil. This unexpected discovery underscores the significant promise of this unconventional source. Squalene ; Extraction (chemistry) ; Abiotic component ; Triterpene ; Wastewater ; Resource recovery ; Terpene Petroleum Processing and Analysis ; Process Optimization and Integration ; Chemical and Physical Properties in Aqueous Solutions
Authors: Kishori P. Sutar | Utkarsh Shashtri | Vinayak Patil | Atharv Milind Lad | Nagaprajwal Anantha Araga | Gangayya Wakkundmath
Source: Journal of Young Pharmacists (article, 2025-11-13)
Field: Chemistry — Analytical Chemistry

A Novel Sustainable UV Spectrophotometric Approach for the Quantification of Amisulpride in Bulk and Nanoformulations BackgroundSchizophrenia is a persistent neuropsychiatric condition that requires precise drug delivery to the brain for effective treatment. Amisulpride, a second-generation antipsychotic, has low oral bioavailability and struggles to cross the blood–brain barrier, thus requiring innovative formulation techniques and dependable analytical methods. The aim of the proposed research work was to develop and validate an eco-friendly UV spectroscopy for measuring amisulpride in bulk drugs, niosomal formulations, and commercial products, promoting sustainable pharmaceutical quality control.Materials and MethodsA UV spectrophotometric approach was developed using a methanol: water (77:23) solvent mixture, with detection at 280 nm. Validation followed ICH Q2 (R1) guidelines, evaluating linearity, precision, accuracy, robustness, ruggedness, LOD, and LOQ. Amisulpride-loaded niosomes were formulated by the ethanol injection method using Span-60 and cholesterol. Particle size and Zeta potential were analyzed by Malvern Zetasizer.ResultsThe method showed excellent linearity (r² = 0.998), precision (%RSD < 2%), and recovery rates (97–101.3%). LOD and LOQ were found to be 0.58 µg/mL and 1.2 µg/mL, respectively. Niosomes had a particle size of 200.89 nm and a zeta potential of –23.6 mV. This method effectively detected amisulpride in the various formulations.ConclusionThe validated UV method provides a precise, robust, and sustainable alternative to chromatographic techniques, facilitating the routine quality evaluation of amisulpride in advanced nanoformulations. Amisulpride ; Zeta potential ; Bioavailability ; Niosome ; Particle size ; Quality by Design Analytical Methods in Pharmaceuticals ; Advancements in Transdermal Drug Delivery ; Pharmaceutical Quality and Counterfeiting
Authors: Chiranjeev Singh | Prachi Gurudiwan
Source: Journal of cancer research updates (article, 2025-06-19)
Field: Materials Science — Biomaterials

Nanoparticle-Based Drug Delivery Systems for Tumor Treatment: Advancing Solutions to Overcome Drug Resistance The potential of nanoparticles (NPs) as a drug delivery mechanism (DDM) has prompted extensive study and use of nanotechnology in tumor cell (TC) treatment. Compared to conventional medications, NP-based DDM offers greater stability and biocompatibility, enhanced absorption and preservation, and focused accuracy, which are some of its unique advantages. This drug-carrying technology has reached a new level with the use and improvement of composite nanoparticles (NPs), which combine the unique characteristics of multiple NPs. Additionally, NP-based DDMs have demonstrated effectiveness in overcoming cancer-related drug resistance (DR). Improving medical translation must address limited dose capacity, stability limitations, and potential harmful effects. Researchers are exploring ways to enhance DDM, including the development of novel drug-encapsulating techniques and modifications to NP surfaces. Potentially huge gains in treatment efficacy may result from optimizing medication integration in such systems. One obstacle to medical translation is stability issues. Applying protective covers and improving formulations are two methods that researchers are exploring to extend the lifespan of NPs. Additionally, before progressing with clinical trials, efforts are being made to minimize the likelihood of negative side effects by carefully selecting compounds that are biologically compatible for NP synthesis and conducting comprehensive toxicity evaluations. Following that, we continue with the innovation of nanoparticle design and functionalization; these types of delivery systems are poised to play a key role in various areas of next-generation tumour therapies. Which provides various offers through robust pathways to overcoming drug resistance, accelerating clinical translation. Drug delivery ; Nanotechnology ; Drug ; Biocompatibility ; Computer science ; Biochemical engineering ; Risk analysis (engineering) ; Materials science ; Medicine ; Pharmacology ; Engineering Nanoparticle-Based Drug Delivery ; Graphene and Nanomaterials Applications ; RNA Interference and Gene Delivery
Authors: Olga Mukhamedzhanova | A.A. Alferova
Source: Nanotechnologies in Construction A Scientific Internet-Journal (article, 2025-06-30)
Field: Materials Science — General Materials Science

Assessment of decorative nano-plaster for fire safety Introduction.In tests for fire and explosion hazard of materials, various factors influence the desired value and its variation.All these factors affect the correct classification of a material into a fire hazard group, which ultimately determines its potential use.For instance, on escape routes from a building, it is essential to use non-combustible materials (Group N) for finishes.For example, on escape routes from the building, it is necessary to use non-combustible materials (group N) for finishing.Therefore, to determine the actual group (class), it is necessary to determine not only the desired value, but also its data spread.Methods and materials.Baumit Nanopore decorative plaster was tested for flammability parameters to classify the material as either flammable or nonflammable.Results.Discussion.Tests of decorative plaster Nanopor "Baumit" showed the following results: loss of mass of the sample is P = 7.00.3%;temperature increase in the furnace is 4,61,7 C; duration of stable flame combustion is 1.0 0.1 s.In accordance with p. 5.2 of GOST 30244-94 this building material is referred to non-combustible materials, because the values of flammability parameters are within the permissible norm.Loss of mass of decorative plaster samples after fire exposure decreased by only 7%, due to the loss of moisture during heating of plaster samples.And the uncertainty on the mass loss of decorative plaster is about 4%.The temperature increase in the oven during the tests of plaster is about 5 C, while the norm is not more than 50 C.Relative expanded uncertainty on the temperature rise in the furnace is 36%.Duration of stable flame combustion of plaster is 1 s, while the norm is not more than 10 s.The spread of data on this indicator is 10%.Conclusion.The analysis of the obtained data showed that the expanded uncertainty on flammability parameters ranges from 4 to 40%, which significantly affects the deviation of the measurement result from the true value, as well as the correctness of assigning the group (class) of fire danger to the material. Fire safety ; Nano- ; Forensic engineering ; Engineering ; Materials science ; Composite material ; Civil engineering Material Properties and Applications
Authors: Chia-Chun Pan | Munseong Bae | Hongtao Wang | Jae-Sung Lim | Ranjith Rajasekharan Unnithan | Joel K. W. Yang | Hsiao L. Chung | Sejeong Kim
Source: ArXiv.org (preprint, 2025-01-22)
Field: Chemistry — Spectroscopy

Inverse Design of Chiral Structures for Giant Helical Dichroism Investigating chiral light-matter interactions is essential for advancing applications in sensing, imaging, and pharmaceutical development. However, the chiroptical response in natural chiral molecules and subwavelength chiral structures is inherently weak, with the characterization tool limited to optical methods that utilize the light with spin angular momentum (SAM). To overcome this, orbital angular momentum (OAM) beams, characterized by helical wavefronts, have emerged as a compelling research focus. Helical dichroism (HD) describes the differential absorbance of OAM beams with opposite signs of topological charges. By using inverse design with adjoint methods for topology optimization, we design the chiral structure optimized to increase HD response under OAM beam incidence, demonstrating a giant HD response of ~107% with topological charges $|\pm\ell|$ = 3 at the wavelength of 800 nm. This study reveals distinct helicity-dependent interactions between the structure and OAM beams, highlighting the potential for custom-tuned chiroptical responses. Circular dichroism ; Inverse ; Materials science ; Crystallography ; Chemistry ; Mathematics ; Geometry Molecular spectroscopy and chirality
Authors: Xufei Fang | Lars Dörrer | Svetlana Korneychuk | Maria Vrellou | Alexander Welle | Stefan Wagner | Astrid Pundt | Harald Schmidt | Christoph Kirchlechner
Source: Journal of the American Ceramic Society (article, 2025-10-05)
Field: Materials Science — Materials Chemistry

Hydrogen response to high‐density dislocations in bulk perovskite oxide SrTiO <sub>3</sub> Abstract Hydrogen plays an increasingly important role in green energy technologies. For instance, proton‐conducting oxides with high performance for fuel cell components or electrolyzers need to be developed. However, this requires a fundamental understanding of hydrogen‐defects interactions. Although point defects and grain boundaries in oxides have been extensively studied, the role of dislocations as line defects remains less understood, primarily due to the challenge for effective dislocation engineering in brittle oxides. In this work, we demonstrate the impact of dislocations in bulk single‐crystal perovskite oxide SrTiO 3 on hydrogen uptake and diffusion using deuterium as tracer. Dislocations with a high density up to ∼10 14 /m 2 were mechanically introduced at room temperature. Exposing this dislocation‐rich region and the reference regions (with a dislocation density of ∼10 10 /m 2 ) to deuterium at 400°C for 1 h, followed by secondary ion mass spectrometry measurements, we observed a ∼100 times increase in deuterium incorporation in the dislocation‐rich region. The result suggests that dislocations in oxides can act as an effective reservoir for deuterium. This proof‐of‐concept brings new insights into the emerging hydrogen‐dislocation interactions in functional oxides. Dislocation ; Hydrogen ; Perovskite (structure) ; Grain boundary ; Crystallographic defect ; Oxide ; Brittleness Electronic and Structural Properties of Oxides ; Advancements in Solid Oxide Fuel Cells ; Ferroelectric and Piezoelectric Materials
Authors: Maher Medini | Leila Ben Haj Said | Imen Abcha | Sihem Bellagha
Source: International Journal of Innovative Approaches in Agricultural Research (article, 2025-12-17)
Field: Chemistry — Organic Chemistry

Green Onion (Allium Cepa L.) Leaves As Natural Additive For Improving Vegetable Oil Quality In Canned Tuna Soybean oil is among the most popular vegetable oils, and is widely used in the food industry, in particular in canned tuna (CT). During processing, soybean oil oxidation induces changes that result in a lower quality. Thus, in this study, we aimed to enrich soybean oil (CT covering oil) using onion leaf powder (OLP) as source of natural antioxidants with potential health promoting effects. The OLP was dried under optimized conditions and added to soybean oil at four different doses (0%; 0.5%; 1%; 1.5% and 2%). All unenriched and enriched soybean oils were used as covering oil in CT which were sterilized at 115 °C and 1.3 bar for 75 min. Quality indices including color, total phenolic content (TPC), total flavonoid content (TFC), antioxidant activity (TEAC), fatty acid composition, and peroxide value (PV) of CT covering oil were carried out on different doses of added OLP as well as on the control sample. The obtained results showed that the addition of OLP in CT allowed the enhancement of the oil covering color that became close to that of extra virgin olive oil. In addition, our outcomes revealed that the addition of OLP improved soybean oil functional properties by significantly increasing of TPC, TFC and TEAC (P Soybean oil ; Peroxide value ; Vegetable oil ; Flavonoid ; Antioxidant ; Tuna ; Fatty acid Edible Oils Quality and Analysis ; Garlic and Onion Studies ; Nuts composition and effects
Authors: Mohamed Fekrouni | Abdelhafid Benomar | Mouna Ameggouz | Brahim Mojemmi | Saad Chakkor
Source: Tropical Journal of Natural Product Research (article, 2025-08-31)
Field: Materials Science — Biomaterials

Transforming Oral Drug Delivery: A Thrilling Journey of Three Decades of Innovation and Breakthroughs Oral Drug delivery systems (ODDS) play a crucial role in modern pharmacotherapy, enhancing the efficacy and safety of drug treatments. This study presents a comprehensive bibliometric analysis of drug delivery system (DDS) research trends over the past 32 years (1992–2024), providing new insights into the evolution of this field. Using a dataset of 437 documents from 161 journals, books, and conference proceedings, bibliometric methods were applied to identify influential authors, key research themes, and international collaboration patterns. Co-citation analysis revealed the significant impact of prominent contributors such as Attwood D, Miyazaki S, Kubo W, and Liu Y on advances in DDS. Keyword clustering analysis revealed dominant research themes, including nanoparticles, polymers, oral bioavailability, and targeted delivery. International collaborations accounted for 24.49% of the total co-authorship, reinforcing theinternational nature of DDS research. This review also offers a critical examination of publication growth, highlighting emerging trends such as nanotechnology and personalized medicine, while addressing gaps in clinical translation, mechanistic understanding, and drug resistance. Unlike previous bibliometric studies, this study offers a longitudinal perspective on DDS research, mapping both historical evolution and contemporary developments. The bibliometric methods employed ensure quantifiable information on the trajectory of the field, guiding future research directions and fostering collaborative advances. By synthesizing trends and identifying strategicgaps, this study provides a valuable reference for researchers and policymakers, facilitating evidence-based decision-making to improve drug delivery technologies and therapeutic outcomes Medicine ; Drug delivery ; Drug ; Pharmacology ; Nanotechnology ; Materials science Nanoparticle-Based Drug Delivery ; Advanced Drug Delivery Systems ; Graphene and Nanomaterials Applications
Authors: Eldrin Arguelles
Source: Recoletos Multidisciplinary Research Journal (article, 2025-04-12)
Field: Materials Science — Biomaterials

New Records of Subaerial Epilithic Algae from Elevated Rock Surfaces in Mt. Makiling Forest Reserve Laguna, Philippines Background: Subaerial microalgal communities, particularly those inhabiting elevated rock surfaces, remain understudied in the Philippines. This study presents the first floristic survey of microalgae from such unique habitats within the Mt. Makiling Forest Reserve. Methods: Rock surface samples were collected from various elevations in the reserve and subjected to morphological examination using light microscopy. Species were identified using standard morphological techniques and taxonomic references. Results: A total of 18 species of microalgae were described taxonomically, of which seven species belonged to Cyanophyceae, five species to Bacillariophyceae, three species to Chlorophyceae, two species to Trebouxiophyceae, and one species to Mediophyceae. Notably, Synechococcus elongatus (Nägeli) Nägeli, a rare cyanobacterium, and Stephanocyclus meneghinianus (Kützing) Kulikovskiy, Genkal &amp; Kociolek, a diatom, are reported for the first time in the Philippines. All documented taxa represent new distributional records for this habitat type. This survey significantly expands the known diversity of subaerial microalgae in the country and underscores the ecological importance of rock surface habitats as reservoirs of algal biodiversity. Conclusion: These findings provide critical taxonomic and biogeographic data that can support further ecological and conservation studies. Subaerial ; Algae ; Ecology ; Forest reserve ; Geography ; Geology ; Forestry ; Paleontology ; Biology Diatoms and Algae Research