jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Jayakrishnan Aerathupalathu Janardhanan | Hsiao‐hua Yu
Source: Nanoscale (review, 2024-01-01)
Field: Materials Science — Polymers and Plastics

Recent advances in PEDOT/PProDOT-derived nano biosensors: engineering nano assemblies for fostering advanced detection platforms for biomolecule detection With the recent unprecedented emergence of a global pandemic, unknown diseases and new metabolic patterns expressing serious health issues, the requirement to develop new diagnostic tools, therapeutic solutions, and healthcare and environmental monitoring systems are significantly higher in the present situation. Considering that high sensitivity, selectivity, stability and a low limit of detection (LOD) are inevitable requirements for an ideal biosensor, the class of conducting polymers of poly(3,4-ethylenedioxythiophene) (PEDOT) and recently poly(3,4-propylenedioxythiophene) (PProDOT) materials have been demonstrated to be promising candidates for designing sensor devices. Nanostructure engineering of these polymeric materials with tunable surface properties and side chain functionalization to enable sensor probe conjugation combined with signal amplification devices such as OECTs and OFETs can fulfil the requirements of next-generation smart nano-biosensors. In this review, we analyze recent reports on PEDOT/PProDOT nanostructures and nanocomposites for developing nano-biosensors and their application in the detection of different biomarkers, environmental, toxicology, marine and aquatic monitoring, forensic and illicit drug detection, <i>etc</i>. In addition, we discuss the challenges associated with the design of PEDOT/PProDOT nano-biosensors and future perspectives on the exploration of novel sensor platforms, particularly PProDOT derivatives for bioelectronics and novel design strategies for next-generation smart nano-biosensors. Nano- ; Nanotechnology ; Biomolecule ; Biosensor ; Materials science ; PEDOT:PSS Conducting polymers and applications ; Advanced biosensing and bioanalysis techniques ; Electrochemical sensors and biosensors
Authors: A.S. Darmenbayeva | R. Reshmy | Bakytgul Massalimova | Nessipkhan Bektenov | Raushan Taubayeva | Karlygash Zh. Bazarbaeva | M. Kurmanaliev | Zhazira Mukazhanova | А.N. Nurlybayeva | Kamila Bulekbayeva | Aisulu Kabylbekova | Aisulu Ungarbayeva
Source: Molecules (review, 2024-12-18)
Field: Materials Science — Biomaterials

Cellulose-Based Sorbents: A Comprehensive Review of Current Advances in Water Remediation and Future Prospects Cellulose-based sorbents are promising materials for wastewater treatment due to their environmental friendliness, biodegradability, and high sorption capacity. This paper presents an overview of cellulose modification methods, including carboxylation, amination, oxidation, graphene, and plasma treatments, as well as combined approaches. Their effect on key physicochemical properties, such as porosity, morphology, and chemical stability, is considered. Examples from the literature confirm the effectiveness of modified cellulose sorbents in removing heavy metal ions and organic pollutants from wastewater. The analysis shows that combined methods allow for creating materials with improved characteristics that are resistant to extreme operating conditions. The main advantages and disadvantages of cellulose sorbents, as well as challenges associated with their scalability and cost-effectiveness, are discussed. The paper emphasizes the importance of further research to advance these materials as a key element of sustainable water treatment technologies. Cellulose ; Wastewater ; Environmental remediation ; Sewage treatment ; Materials science ; Biodegradation ; Environmental science ; Waste management ; Chemical engineering ; Chemistry ; Organic chemistry ; Environmental engineering ; Contamination ; Engineering Advanced Cellulose Research Studies ; Adsorption and biosorption for pollutant removal ; Electrospun Nanofibers in Biomedical Applications
Authors: Jinghui Sun | Yifei Yan | Xuanxuan Chen | Zhiwei Huang | Yinhua Huang
Source: Chemical Science (article, 2024-01-01)
Field: Chemistry — Organic Chemistry

Palladium-catalyzed regio- and stereo-selective phosphination of cyclic biarylsulfonium salts to access atropoisomeric phosphines A palladium-catalyzed regio- and stereo-selective phosphination of cyclic biarylsulfonium salts (racemic) with HPAr<sup>3</sup>Ar<sup>4</sup> for straightforward synthesis of atropoisomeric phosphines (P,S-ligands) bearing a stereogenic axis or both a stereogenic axis and a P-stereogenic center is reported. The high reactivity and regio- and stereo-selectivity originate from the torsional strain release and palladium catalysis, and the construction of a P-stereogenic center is enabled by an efficient dynamic kinetic resolution. The high performance of the nascent P,S-ligands has been demonstrated in palladium-catalyzed asymmetric allylic substitutions, indicating the great potential of the present methodology. Palladium ; Catalysis ; Chemistry ; Combinatorial chemistry ; Organic chemistry Axial and Atropisomeric Chirality Synthesis ; Asymmetric Hydrogenation and Catalysis ; Catalytic C–H Functionalization Methods
Authors: Ranran Luo | Chenxi Zhang | Z.Y. Zhang | Pengpeng Ren | Zhongsheng Xu | Yun Liu
Source: Nanoscale (review, 2024-12-24)
Field: Materials Science — Materials Chemistry

NIR-II upconversion nanomaterials for biomedical applications As a nonlinear optical phenomenon, upconversion (UC) occurs when two or more low-energy excitation photons are sequentially absorbed and emitted. Upconversion nanomaterials exhibit superior photostability, non-invasiveness, a unique near-infrared anti-Stokes shift, and enhanced tissue penetration capability. However, general upconversion nanomaterials typically utilize visible light (400-700 nm) for excitation, leading to limited tissue penetration, background signal interference, limited excitation efficiency and imaging quality issues due to tissue absorption and scattering. The increasing use of upconversion nanomaterials in the near-infrared one-region (NIR-I) window (700-900 nm) offers benefits such as enhanced penetration into biological tissues, relatively improved imaging resolution, and lower spontaneous luminescence, although these materials are still susceptible to background signals, limiting their effectiveness in high signal-to-noise ratio imaging. This distinctive wavelength conversion endows upconversion nanomaterials in the NIR-II region with extraordinary potential for diverse applications. Biomedical research has primarily focused on biomedical imaging for disease diagnosis and treatment, as well as biomarker detection. Nonetheless, studies specifically targeting the NIR-II window remain limited. This paper summarizes the latest research progress on upconversion nanomaterials in the NIR-II region. It begins by introducing the preparation methods for these materials in the NIR-II, followed by their applications in imaging and biological contexts. Lastly, it discusses the primary challenges and future prospects of upconversion materials in NIR-II, aiming to promote their development. Photon upconversion ; Nanomaterials ; Nanotechnology ; Materials science ; Window (computing) ; Near-infrared spectroscopy ; Optoelectronics ; Computer science ; Doping ; Optics ; Physics ; World Wide Web Luminescence Properties of Advanced Materials ; Nanoplatforms for cancer theranostics ; Perovskite Materials and Applications
Authors: Shanmuga Priya Mohanaraman | Ramalingam Chidambaram
Source: Heliyon (review, 2024-08-01)
Field: Materials Science — Materials Chemistry

A holistic review on red fluorescent graphene quantum dots, its synthesis, unique properties with emphasis on biomedical applications Graphene quantum dots (GQDs) are an evolving class of carbon-based nanomaterial, seizing tremendous attention owing to their intense optical property, engineered shapes and structures, and good photostability. Being a zero-dimensional form of carbon structure, GQDs have superior photoluminescent behavior, tunable emission and absorption, excellent biocompatibility, low cytotoxicity, hydrophilic nature, modifying surface states. Their water dispersibility and functionalized surface structure, involving heteroatoms and various functional groups onto the surface of GQDs, make them particularly suitable for biological applications. Based on their absolute luminescence properties, GQDs emit blue, green, yellow, and red light under ultraviolet irradiation. Amongst the three colors, red luminescence can achieve deeper penetration of light into tissues, good cellular distribution, bio-sensing property, cell imaging, drug delivery, and serves as a better candidate for photodynamic therapy. The overall objective of this review is to provide a comprehensive overview of the synthesis methods for red fluorescence graphene quantum dots (RF-GQDs), critical comparative analyses of spectral techniques used for their characterization, the tunable photoluminescence mechanisms underpinning red emission, and the significance of chemically functionalizing GQDs' surface edges in achieving red fluorescence are discussed in depth. This review also discusses the effective biological applications and critical challenges associated with RF-GQDs are examined, providing insights into their future potential in clinical and industrial applications. Graphene ; Quantum dot ; Materials science ; Nanotechnology ; Photoluminescence ; Biocompatibility ; Nanomaterials ; Fluorescence ; Luminescence ; Surface modification ; Biological imaging ; Carbon quantum dots ; Optoelectronics ; Chemistry ; Optics Carbon and Quantum Dots Applications ; Nanocluster Synthesis and Applications ; Graphene and Nanomaterials Applications
Authors: Amogh Gorantla | Jacques Hall | Anneliese Troidle | Jelena M. Janjic
Source: Micromachines (article, 2024-04-15)
Field: Materials Science — Biomaterials

Biomaterials for Protein Delivery: Opportunities and Challenges to Clinical Translation The development of biomaterials for protein delivery is an emerging field that spans materials science, bioengineering, and medicine. In this review, we highlight the immense potential of protein-delivering biomaterials as therapeutic options and discuss the multifaceted challenges inherent to the field. We address current advancements and approaches in protein delivery that leverage stimuli-responsive materials, harness advanced fabrication techniques like 3D printing, and integrate nanotechnologies for greater targeting and improved stability, efficacy, and tolerability profiles. We also discuss the demand for highly complex delivery systems to maintain structural integrity and functionality of the protein payload. Finally, we discuss barriers to clinical translation, such as biocompatibility, immunogenicity, achieving reliable controlled release, efficient and targeted delivery, stability issues, scalability of production, and navigating the regulatory landscape for such materials. Overall, this review summarizes insights from a survey of the current literature and sheds light on the interplay between innovation and the practical implementation of biomaterials for protein delivery. Nanotechnology ; Leverage (statistics) ; Payload (computing) ; Drug delivery ; Computer science ; Systems engineering ; Engineering ; Materials science Electrospun Nanofibers in Biomedical Applications ; 3D Printing in Biomedical Research ; RNA Interference and Gene Delivery
Authors: Fabio Santanni | Alberto Privitera
Source: Advanced Optical Materials (article, 2024-05-17)
Field: Materials Science — Materials Chemistry

Metalloporphyrins as Building Blocks for Quantum Information Science Abstract The intrinsic quantum nature of molecules opens exciting opportunities for developing the field of quantum information science. In this context, porphyrins stand out as ideal building blocks for quantum technologies thanks to their unique optical and electrical properties as well as their capacity to accommodate metal atoms and ions. This review bridges the chemistry and physics of porphyrins, providing an overview of recent advances in porphyrin‐based molecular qubits. Starting from qubits, the review explores the potential of porphyrin units to combine, leading to the formation of quantum logic gates and hierarchical higher‐dimensional structures. Next, the exploitation of porphyrins' unique photophysical properties for realizing long‐lived high spin states is examined. These states are promising for the photogeneration of multi‐level systems and the optical initialization and control of molecular qubits. With a critical eye on the current state‐of‐the‐art, the review elucidates the future perspectives of porphyrins for advancing quantum technologies. Materials science ; Quantum ; Quantum information science ; Nanotechnology ; Engineering physics ; Quantum entanglement ; Quantum mechanics ; Physics Porphyrin and Phthalocyanine Chemistry ; Photosynthetic Processes and Mechanisms ; Surface Chemistry and Catalysis
Authors: Bianliang Miao | Yushu Wang | Yi Liu | Gaohuan Da | Yu Wang | Xin Chen | Zhengzhong Shao
Source: Advanced Functional Materials (article, 2024-01-04)
Field: Materials Science — Biomaterials

An Interfacial‐Assembled Self‐Supporting Nanofilm Induced by Strong Intermolecular Interaction between Silk Fibroin and Lysozyme Abstract Organic ultrathin nanofilms are increasingly favored in a wide range of applications, including flexible photonics and electronics, smart skin devices, sensing, and bioinspired designs, due to their high flexibility, chemical activity, and stimuli‐responsiveness. To create large‐area, robust, and freestanding nanofilms efficiently, a protein interfacial cooperative assembly technique that utilizes silk fibroin and lysozyme as building blocks is developed. The strong intermolecular interaction between these two proteins, coupled with the abundant intra‐ and intermolecular β‐sheets, confers remarkable mechanical robustness to the nanofilms with thicknesses as low as 50 nm. Consequently, these nanofilms exhibit the unique ability to stand freely in the air and can be conformally transferred to substrates of different types and topographies, forming stable, and versatile nanocoatings. The advantageous attributes of their ultrathinness, large‐scale homogeneity, robustness, and rapid and tunable responsiveness facilitate the construction of ultrasensitive photonic architectures and organic–inorganic hybrid multilayers with outstanding optical and mechanical properties. It is envisioned that these all‐protein‐based robust nanofilms with unique nanoscale effects can be easily integrated into various advanced technological platforms to enable adaptive, multifunctional, and intelligent systems with exceptional mechanical strength. Materials science ; Nanotechnology ; Nanoscopic scale ; SILK ; Photonics ; Fibroin ; Intermolecular force ; Robustness (evolution) ; Polymer ; Optoelectronics ; Molecule ; Composite material Silk-based biomaterials and applications ; Polymer Surface Interaction Studies ; Supramolecular Self-Assembly in Materials
Authors: Jing Hu | Yi Liu | Wei Xu
Source: Forests (article, 2024-04-09)
Field: Materials Science — Materials Chemistry

Influence of Cell Characteristics on the Construction of Structural Color Layers on Wood Surfaces When utilizing microspheres to construct structural color layers on wood surfaces, the cellular structure of wood can influence the self-assembly of microspheres and the resulting structural color layers. To investigate this influence, seven types of wood were selected in this study, and structural color layers were constructed on their surfaces. A comparative analysis was conducted on the color production and macro and micro morphologies of the structural color layers on different wood surfaces, along with an examination of the types and causes of surface defects. The study found that when a microsphere-containing emulsion was applied to a wood surface, the emulsion tended to flow along the vessels of hardwood and the tracheids of softwood. Overflow or seepage of the emulsion could lead to a reduction in the number of microspheres per unit area, resulting in uneven thickness and uneven color generation of the structural color layers. Although the structural color layers on different wood exhibited the same color, there were variations in their tones, appearance, and morphology. Defects such as minor bumps and pits were present on the structural color layers. Bump defects might originate from microsphere encapsulation of fiber bundles or the displacement of air within vessel lumens by emulsion, while pits were mainly caused by the inflow of emulsion into the vessel lumens. This study clarified the influence of wood surface cells, particularly vessels and tracheids, on the construction and color production of structural color layers, providing support for the controllable modification of wood surfaces using structural colors. Tracheid ; Emulsion ; Materials science ; Composite material ; Softwood ; Structural coloration ; Chemistry ; Botany ; Xylem Pickering emulsions and particle stabilization ; Aeolian processes and effects ; Advanced Cellulose Research Studies
Authors: Jie Zhang | Wenwen Zhou | Jianfeng Zhao | Liangliang Xu | Xue‐Kai Jiang | Zhiwen Li | Yongwu Peng | Gao Li
Source: Small (article, 2024-11-03)
Field: Materials Science — Materials Chemistry

Intrareticular Exciton Effects Regulate Photocatalytic Activity in Donor–Acceptor Olefin‐Linked Covalent Organic Frameworks Olefin-linked covalent organic frameworks (OL-COFs) show great promise for visible-light-driven photocatalysis. Manipulating atomic-level donor-acceptor interactions in OL-COFs is key to understanding their exciton effects in this system. Here, three OL-COFs are presented with orthorhombic lattice structures, synthesized via Knoevenagel polycondensation reaction of terephthalaldehyde and tetratopic monomers featuring phenyl, benzo[c][1,2,5]oxadiazole, and benzo[c][1,2,5]thiadiazole moieties. These OL-COFs feature tunable donor-acceptor interactions, making them ideal for studying exciton effects in olefin-linked systems. Comprehensive analyses, including temperature-dependent photoluminescence spectra, ultrafast spectroscopy, and theoretical calculations, reveal that stronger donor-acceptor interactions lead to reduced exciton binding energy (E<sub>b</sub>), accelerated exciton dissociation, and longer-lived photogenerated charges, thereby enhancing photocatalytic performance. Notably, The TMO-BDA COF, with the lowest E<sub>b</sub>, demonstrates superior photocatalytic activity in one-pot sequential organic transformation and excellent catalytic performance in gram-scale reactions, highlighting its potential for practical applications. This work provides valuable insights into regulating the exciton effect at the molecular level in OL-COFs, offering pathways to enhance photocatalytic efficiency. Photocatalysis ; Exciton ; Materials science ; Photochemistry ; Acceptor ; Photoluminescence ; Covalent bond ; Ternary operation ; Catalysis ; Chemistry ; Organic chemistry ; Optoelectronics Covalent Organic Framework Applications ; Advanced Photocatalysis Techniques ; Luminescence and Fluorescent Materials
Authors: Étienne Derat | Géraldine Masson | Aurélie Claraz
Source: Angewandte Chemie International Edition (article, 2024-04-30)
Field: Chemistry — Organic Chemistry

Electrochemically‐Driven 1,4‐Aryl Migration via Radical Fluoromethylation of N‐Allylbenzamides: a Straightforward Access to Functionalized β‐Arylethylamines An electrochemical radical Truce Smiles rearrangement of N-allylbenzamides is documented herein. The selective 1,4-aryl migration was triggered by the radical fluoromethylation of the alkene providing a direct route to fluoro derivatives of the highly privileged β-arylethylamine pharmacophore. This practical transformation utilizes readily available starting materials and employs an electrical current to drive the oxidative process under mild reaction conditions. It accommodates a variety of migratory aryl groups with different electronic properties and substitution patterns. Careful selection of the protecting group on the nitrogen atom of the N-allylbenzamide is crucial to outcompete the undesired 6-endo cyclization and achieve high level of selectivity towards the 1,4-aryl migration. DFT calculations support the reaction mechanism and unveil the origin of selectivity between the two competitive pathways. Pharmacophore ; Aryl ; Alkene ; Combinatorial chemistry ; Selectivity ; Chemistry ; Aryl radical ; Leaving group ; Electrochemistry ; Alkyl ; Stereochemistry ; Organic chemistry ; Catalysis Radical Photochemical Reactions ; Catalytic C–H Functionalization Methods ; Fluorine in Organic Chemistry
Authors: Nicholas B. Hamilton | Steve Arns | Mee Shelley | Irene Bechis | John C. Shelley
Source: Molecular Pharmaceutics (article, 2024-12-10)
Field: Chemistry — Organic Chemistry

Calculating Apparent p <i>K</i> <sub>a</sub> Values of Ionizable Lipids in Lipid Nanoparticles Creating new ionizable lipids for use in lipid nanoparticles (LNPs) is an active field of research. One of the critical properties for selecting suitable ionizable lipids is the apparent p<i>K</i><sub>a</sub> value of the lipid as formulated in an LNP. We have developed a structure-based, computational methodology for the prediction of the apparent p<i>K</i><sub>a</sub> value of ionizable lipids within LNPs and have tested it using the lipid formulations in the mRNA LNP COVID-19 vaccines COMIRNATY and Spikevax, and the siRNA LNP therapeutic Onpattro. The calculation was also applied to Lipid A, a variant of the ionizable lipid used in COMIRNATY. Chemistry ; Nanoparticle ; Nanotechnology ; Materials science Free Radicals and Antioxidants ; Computational Drug Discovery Methods ; Lipid Membrane Structure and Behavior
Authors: Naoki Higashitarumizu | Shu Wang | Shifan Wang | Hyung‐Jin Kim | James Bullock | Ali Javey
Source: Nano Letters (review, 2024-10-15)
Field: Materials Science — Materials Chemistry

Black Phosphorus for Mid-Infrared Optoelectronics: Photophysics, Scalable Processing, and Device Applications High efficiency mid-infrared (λ = 3-8 μm) light emitters and photodetectors are pivotal for advancing next-generation optoelectronics. However, narrow-bandgap semiconductors face fundamental challenges such as pronounced nonradiative carrier recombination and thermally generated noise, which impede device performance. Recently, two-dimensional layered black phosphorus (BP) and its alloys have attracted substantial interest for mid-infrared device applications, demonstrating superior performance relative to conventional III-V and II-VI semiconductors with similar bandgaps. In this review, we discuss the optical properties of BP, contrasting these with those of covalent compounds. Owing to its inherently self-terminated surface structure and reduced nonradiative recombination, BP exhibits high performance in light emission and photodetection at room temperature. Furthermore, this review highlights recent advances in the large-area processing of BP thin films, paving the way for practical device applications and integration. Finally, we explore ongoing challenges and emerging opportunities in the utilization of BP for functional mid-infrared devices. Black phosphorus ; Infrared ; Optoelectronics ; Scalability ; Materials science ; Nanotechnology ; Optics ; Physics ; Computer science 2D Materials and Applications ; Perovskite Materials and Applications ; Photonic and Optical Devices