jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Ioannis Filippos Kyriakidis | Anargiros Karelis | Nikolaos Kladovasilakis | Eleftheria Maria Pechlivani | Konstantinos Tsongas
Source: Fibers (article, 2025-11-24)
Field: Materials Science — Polymers and Plastics

Valorization of Natural Byproducts Through Additive Manufacturing for Ecologically Sustainable Composite Materials: A Literature Review This review paper explores the influence of natural byproducts on polymer matrices via additive manufacturing (AM), focusing specifically on the development of eco-friendly composite materials. A broad range of lignocellulosic residues—such as sawdust, wood chips, bark, and other related byproducts—are evaluated for their potential incorporation into polymer matrices to create filaments and pastes appropriate for AM techniques. The paper initially examines the features of natural byproducts and their typical uses, then evaluates the benefits that AM presents in comparison to conventional manufacturing techniques. Special emphasis is placed on the physicochemical and mechanical properties of the developed composites, encompassing their thermal characteristics (glass transition temperature, melting point, and stability), density, and mechanical behavior under both static and dynamic loading. Furthermore, the environmental effects of these composites are thoroughly assessed through Life Cycle Assessment (LCA), highlighting their contribution to minimizing ecological footprints and promoting circular economy initiatives. Collectively, the findings indicate that the additive manufacturing of composites derived from natural byproducts represent a promising pathway toward sustainable industrial production. Life-cycle assessment ; Natural (archaeology) ; Circular economy ; Composite number ; Sustainable development ; Natural polymers ; Natural fiber ; Industrial ecology Natural Fiber Reinforced Composites ; Additive Manufacturing and 3D Printing Technologies ; Innovations in Concrete and Construction Materials
Authors: Zackary Rehfuss | Kaiwen Zheng | Stephanie L. Gould | Kater Murch | Sihan Ran
Source: arXiv (Cornell University) (preprint, 2025-01-06)
Field: Materials Science — Materials Chemistry

Sub-micron Circuit Fabrication on Diamond Anvils for Mesoscopic High-Pressure Experiments We present a novel fabrication procedure to produce high-quality lift-off structures on diamond anvils extending from the culet down to the slanted facets. Feature sizes down to 500 nm are achieved through the use of a bi-layer resist stack and electron beam lithography. Device structures with strong adhesion to the diamond surface and high abrasion resistance are realized by optimizing the surface treatment. To benchmark our process, we fabricate a multi-lead tungsten circuit to measure changes of the superconducting transition temperature of zirconium across the structural phase transition at $\sim$30 GPa; showing a 4-fold jump of the critical temperature. Our process is easily reproducible in most traditional academic and industrial cleanroom facilities. This work paves the way for complex and high-precision fabrication and measurements inside diamond anvil cells and on other faceted crystalline samples. Mesoscopic physics ; Fabrication ; Diamond ; Materials science ; Optoelectronics ; Nanotechnology ; Engineering physics ; Composite material ; Engineering ; Condensed matter physics ; Physics Diamond and Carbon-based Materials Research ; Gas Dynamics and Kinetic Theory ; Adhesion, Friction, and Surface Interactions
Authors: Andrea A. E. Gaertner | Nathan R. Perron | Heeren M. G. Anderholm | Daniel C. Whitehead | Julia L. Brumaghim
Source: Frontiers in Chemical Biology (article, 2025-10-17)
Field: Chemistry — Organic Chemistry

Quantifying antioxidant activity of hydrophobic compounds using metal-mediated DNA damage Cellular damage and death caused by oxidative stress by reactive oxygen species play an important role in disease development. Testing the ability of hydrophobic compounds to prevent radical-generated oxidative stress typically involves radical scavenging assays; however, these oxidative stress assays often do not accurately reflect biological outcomes. We present an in vitro assay that quantifiably evaluates the ability of hydrophobic compounds to prevent DNA damage, a biological endpoint that is linked to disease development. This gel electrophoresis assay enables evaluation of a wide range of hydrophobic compounds for metal-mediated hydroxyl radical damage prevention by using high-ethanol concentrations in electrophoretic conditions, and the effects of these high-ethanol conditions on iron- and copper-mediated DNA damage are established. This assay was used to compare the effects of metal-mediated DNA damage and its prevention by polyphenols, bipyridine, and selone antioxidant compounds as well as the radical scavenger edaravone. We also demonstrated that the well-studied glutathione peroxidase mimic ebselen and a group of ebselen derivatives prevent copper-mediated DNA damage with IC 50 values in the 280–450 µM range. These same compounds do not inhibit iron-mediated DNA damage under similar conditions. This DNA-damage assay allows determination of antioxidant properties for hydrophobic antioxidants and drugs using a model system based on metal-mediated oxidative DNA damage, a primary cause of cell death. Ebselen ; Oxidative stress ; DNA damage ; Antioxidant ; Reactive oxygen species ; Scavenger ; DNA ; Radical Free Radicals and Antioxidants ; Genomics, phytochemicals, and oxidative stress ; Antioxidant Activity and Oxidative Stress
Authors: Pégnonsienrè Lacina Soro | Marcellin Konan Kouadio | Fankroma Martial Thierry Koné | Doubi Bi Tra Serges | Konan Jean Louis Konan
Source: Current Journal of Applied Science and Technology (article, 2025-01-07)
Field: Chemistry — Inorganic Chemistry

Effect of Improved Cultivars and Maturity Stage on Physical Parameters, Chemical Indices and Fatty Acid Composition of Coconut Oils from Ivorian Germplasm Aims: This study was conducted to evaluate the effect of improved Cocos nucifera cultivars and maturity on the physical, chemical indices, and fatty acid composition of coconut oils (COs) from Ivorian coconut germplasm for food purposes. Methodology: Improved coconut cultivars were obtained from the experimental field West Tall African (WAT+), Rennell Island Tall (RIT+), and local hybrids (PB121+ and PB113+) were harvested at different stages of maturity :10, 11, and 12 months after pollination. COs from Low-heat extraction were obtained from ly prepared coconut milk. A total of 12 COs samples were evaluated for various physico-chemical quality properties. Place and Duration of Study: Genetics and Plant Breeding Department of the Marc Delorme Coconut Research Station, Southern Côte d'Ivoire 2023. Results: The two-way ANOVA showed a significant effect (P &lt; 0.05) of improved variety and maturity of COs on the parameters studied. A high value of yield (82.75%), melting point (24.89 °C), density (0.921), acid value (0.71 mg KOH/g), saponification value (262.83 mg KOH/g), and lauric acid (53.73%) were found for CO from the improved cultivar WAT+. Hybrid (PB121+ and PB113+) coconut oils had higher iodine value (11.79 g I2/100 g), oleic acid (6.61%), and linoleic acid (2.22%) fat compared to Tall (RIT+ and WAT+). All the physico-chemical parameters studied increased with full maturity of the coconut at 12 months. All extracted coconut oils were clear in colour, which could be an important feature to attract consumers. Conclusion: All chemical composition results meet the specifications of several standards, including the Asian Pacific Coconut Community (APCC) and Codex Alimentarius (CODEX STAN 210-1999). This suggests that Ivorian coconut oils could be an effective source of food ingredients that could have a positive impact on the agricultural market, thereby contributing to increasing the income of farming households. Germplasm ; Maturity (psychological) ; Chemical composition ; Cultivar ; Composition (language) ; Coconut oil ; Fatty acid ; Biology ; Horticulture ; Food science ; Botany ; Agronomy ; Chemistry ; Biochemistry ; Organic chemistry ; Psychology Coconut Research and Applications ; Edible Oils Quality and Analysis ; Food Chemistry and Fat Analysis
Authors: K.I. Ilyassova | Zh.N. Moldamuratov | O.D. Seitkazinov | G.S. Abiyeva | A.Z. Tukhtamisheva | М. Paktin
Source: Nanotechnologies in Construction A Scientific Internet-Journal (article, 2025-12-24)
Field: Materials Science — Materials Chemistry

Experimental studies of concrete materials for the restoration of hydraulic structures Introduction.The objective of this research is to substantiate the application of advanced concrete materials for restoring hydraulic structures in Kazakhstan and Central Asia, where service conditions are severe due to sharp temperature swings, sulfate-chloride attack, and high seismicity.The relevance of the study is determined by the widespread deterioration of existing infrastructure and the demonstrated inadequacy of traditional repair methods.Methods and materials.To evaluate the properties of the original concrete and promising repair materials (polymer-modified mortars, geopolymer systems, and ultra-high-performance concrete-UHPC), a comprehensive set of laboratory tests was conducted.The research included: physico-mechanical tests (strength, elastic modulus, adhesion), durability tests (RCPT, NT Build 492, freeze-thaw resistance, sulfate resistance, abrasion-cavitation wear), and micro/nanostructural analysis (SEM/EDS, XRD, nanoindentation).Results and discussion.The original concrete exhibited high permeability (~5.2 thousand C according to RCPT), low adhesion, and significant strength loss under cyclic loading, which can be explained by pronounced porosity and cracking of the structure.UHPC demonstrated minimal permeability (<0.3 thousand C), high adhesion (2.2 MPa), low strength loss under freeze-thaw cycles (3%), and the highest local elastic modulus (40-50 GPa).Geopolymer materials showed strong sulfate resistance (expansion 0.038%) and a fine-pore structure with a low diffusion coefficient (510 -12 m 2 /s).Polymer-modified mortars (PMM) exhibited intermediate characteristics, remaining the most economically feasible option.SEM confirmed the significant densification of the UHPC and geopolymer matrices compared to the original concrete; XRD revealed a reduction in portlandite content and the formation of sulfate-resistant phases in geopolymers, while UHPC showed a predominance of amorphous C-S-H phases.Conclusion.The comprehensive analysis demonstrated that the rational use of materials depends on the balance between durability, reliability, and economic-environmental indicators.UHPC is recommended for zones exposed to intensive cavitation and abrasion; geopolymers are optimal for structures in sulfate environments; and PMM are suitable for localized repairs under budget constraints.The results confirm the effectiveness of a multi-level approach: diagnostics material selection laboratory verification durability prediction practical recommendations.This provides a scientifically grounded basis for designing restoration measures for hydraulic structures. Deformation (meteorology) ; Welding ; Work (physics) ; Displacement (psychology) Structural mechanics and materials ; Innovations in Concrete and Construction Materials ; Grouting, Rheology, and Soil Mechanics
Authors: Taha Kassim Dohadwala | Rabab Hunaid Abbas | Sharin Mary Siji | Soumiya Nadar | Sakina Sakina | Naman Jairath | Hema Patel | Tinatin Zurashvili
Source: Discoveries (article, 2025-09-30)
Field: Materials Science — Biomaterials

Novel Oncologic Strategies in Osteosarcoma Management: Maximizing Impact, Minimizing Harm Doxorubicin (DOX), an anthracycline antibiotic, is pivotal in managing osteosarcoma (OS). Although a cornerstone in the multimodal treatment regimen, its usage is limited by its associated toxicities, such as cardiotoxicity, myelosuppression, and neurotoxicity. This review provides an in-depth discussion of the emerging research aimed at enhancing the overall efficacy and mitigating the undesired side effects of DOX in treating OS. We explore the various drug delivery systems, including polymer-based injectable hydrogels, hydroxyapatite-based systems, and various nanoparticle-based systems such as calcium carbonate nanocrystals and cerium-substituted hydroxyapatite. We also discuss various innovative combination therapies, such as pegylated liposomal DOX with cisplatin and DOX with platinum nanoparticles. Moreover, emerging research into light-sensitive nano-micelles have been highlighted. These methods improve DOX's cytotoxicity and potentially reduce the need for high systemic doses and their associated side effects. The review aims to highlight the promising future in OS treatment by integrating these methodologies to maximize the therapeutic action of DOX and reduce its systemic side effects. Osteosarcoma ; Doxorubicin ; Anthracycline ; Cisplatin ; Drug ; Drug delivery ; Anticancer drug Nanoparticle-Based Drug Delivery ; Sarcoma Diagnosis and Treatment ; Nanoplatforms for cancer theranostics
Authors: América Estefania Estrada Aparicio | Javier Peña
Source: grafica (article, 2025-11-15)
Field: Chemistry — Physical and Theoretical Chemistry

El lenguaje y la vida de los elementos químicos La inteligencia artificial, combinada con la comunicación gráfica, ofrece nuevas posibilidades para representar el lenguaje de los elementos químicos en la educación primaria. Esta aproximación visual y tecnológica no solo facilita la comprensión del universo químico, sino que potencia competencias STEM clave en edades tempranas. Equiparar los símbolos químicos al lenguaje alfanumérico mediante IA permite generar representaciones accesibles, creativas y significativas para los estudiantes, fomentando una alfabetización científica más temprana y contextualizada. Context (archaeology) ; Subject (documents) ; Object (grammar) ; Natural (archaeology) History and advancements in chemistry ; Science Education and Pedagogy ; Educational methodologies and cognitive development
Authors: Wei-Yang Chen | Cui-Qun Chen | Meng Wang | Shou-Shu Gong | Dao‐Xin Yao
Source: ArXiv.org (preprint, 2025-11-03)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Superconductivity of bilayer two-orbital Hubbard model for La$_{3}$Ni$_{2}$O$_{7}$ under high pressure By combining density functional theory (DFT) and density matrix renormalization group calculations, we investigate the unusual pressure dependence of superconducting transition temperature ($T_c$) in the nickelate superconductor La$_{3}$Ni$_{2}$O$_{7}$. Using the hopping integrals and on-site potentials obtained by fitting the DFT band structures, we map a quantum phase diagram of a bilayer two-orbital Hubbard model with increasing pressure in a ladder geometry, which has an intermediate Hubbard repulsion and a Hund's coupling. Near $3/8$ filling, we find a strong spin density wave order, which at $3/8$ filling shows a real-space spin pattern similar to the spin-charge stripe order along a lattice direction. At $21/64$ filling, we find a superconducting phase with interlayer superconductivity (SC) in both the $d_{z^2}$ and $d_{x^2-y^2}$ orbitals, as well as in-plane SC in the $d_{z^2}$ orbital. Intriguingly, the SC is weakened with increasing pressure and transits to a Luttinger liquid above $80$ GPa, which qualitatively agrees with the experimental observations of decreasing $T_c$ with increasing pressure and a transition to Fermi liquid above $80$ GPa in La$_{3}$Ni$_{2}$O$_{7}$. Through a comparative study, we further show that the ratio of interaction to hopping integral, which reduces moderately with increasing pressure, may play a dominant role in the weakening of SC. Our results of this experimentally relevant model not only find a robust SC through suppressing the competing spin density wave order, but also give new insight into the unusual pressure dependence of SC in La$_{3}$Ni$_{2}$O$_{7}$. Superconductivity ; Hubbard model ; Phase diagram ; Bilayer ; Ambient pressure ; Spin (aerodynamics) ; Spin density wave ; Lattice (music) ; Density of states ; Renormalization group Iron-based superconductors research ; Magnetic and transport properties of perovskites and related materials ; Physics of Superconductivity and Magnetism
Authors: Sitong Lai | Kunhui Sun | Yongqing Wu | Xiaolei Wu | Yiqi Yan | Guojing Liu | Xiaoyi Liu | Yuanyuan Ge | Lina Zeng | Ziyu Guo | Shuhong Wang | Ping Wang | Bing Wang | Han Zhang | Xie‐an Yu
Source: Frontiers in Pharmacology (article, 2025-08-22)
Field: Chemistry — Spectroscopy

Cu2+/Cu+ redox-cycling-driven dual-mode sensor for simultaneous monitoring of acetylcholinesterase activity and pesticide exposure This study developed a portable detection platform based on valence interconversion coupled enzyme inhibition with probe responsiveness. The dual-signal output enhanced reliability and the redox-driven mechanism enabled signal amplification. This advancement provided a real-time, portable and rapid detection for AChE activity and pesticide exposure of TCMs, bridging gaps in agricultural safety and pharmaceutical standardization. Acetylcholinesterase ; Cycling ; Pesticide ; Dual mode ; Redox ; Chemistry ; Environmental chemistry ; Biochemistry ; Biology ; Enzyme ; Inorganic chemistry ; Ecology ; Electronic engineering Molecular Sensors and Ion Detection ; Luminescence and Fluorescent Materials ; Electrochemical sensors and biosensors
Authors: Ashutosh Sengar
Source: International Journal of Bioinformatics and Intelligent Computing (article, 2025-08-30)
Field: Materials Science — Biomaterials

Advancements in Targeted Drug Delivery: Innovations in Liposomal, Nanoparticle, and Vesicular Systems Targeted drug delivery has become a miraculous tool in the new millennium of medicine to deliver the greatest therapeutic action, minimize systemic side effects and attain site-specific drug activity. This review offers advances in liposomal, nanoparticle and vesicular drug delivery systems with emphasis on their capacity for maximal bioavailability and regulation of drug release. There has been controversy over the use of some of these other carriers such as tablet formulations, proniosomes and other age-new carriers. Introduction of nanotechnology with biodegradable items and use of artificial intelligence has added new dimensions to patient-specific medicine based on the patient's need. In spite of these developments, regulatory problems, biocompatibility and scale-up manufacture are concerns that persist as barriers to universal clinical use. Some of the recent technologies such as 3D-printed pharmaceuticals, stimuli-responsive nanocarriers and drug design using artificial intelligence have the potential to bypass these concerns. Future direction is also set here in the focus on the application of green drug delivery concepts, precision medicine and combination regimens in setting the future of targeted drug delivery systems. Through ongoing research and technology development, these technologies are poised to revolutionize medicine by maximizing therapeutic effect, reducing side effects and maximizing drug delivery. Liposome ; Drug delivery ; Targeted drug delivery ; Nanotechnology ; Drug ; Drug carrier ; Nanoparticle ; Nanomedicine ; Pharmacology ; Medicine ; Materials science Nanoparticle-Based Drug Delivery ; Advanced Drug Delivery Systems ; Cancer Research and Treatment
Authors: Mykola Sadovyі | Olga V. Riezina | Олена Михайлівна Трифонова | N V Donets
Source: Journal of Physics Conference Series (article, 2025-09-01)
Field: Chemistry — Physical and Theoretical Chemistry

Computer modelling of atomic-molecular states leading to Maxwell distribution Abstract This article examines the dynamics of transitioning from the traditional educational model focused on information accumulation to an innovative information model emphasizing the development and quality of research outcomes within smart educational environments. This approach facilitates the integration of computational resources with the cyber-physical nature of natural phenomena. We address the challenge of computer modelling atomic-molecular gas states subject to Maxwell distribution laws, employing an integrative method of simulated visual-dynamic computer modelling developed using Python’s Matplotlib module. The resulting visualization, termed integrative presentation-dynamic computer visualization, enables the creation of Python programs that construct models of Maxwell’s graphical simulated dynamic distribution. The adjustable parameters within these models provide new insights into the physical essence of molecular velocity distributions. Through this approach, students develop an autonomous worldview oriented toward independent truth-seeking and scientific inquiry. Python (programming language) ; Computational model ; Construct (python library) ; Scientific modelling ; Mathematical model ; Subject (documents) ; Computer modelling ; Distribution (mathematics) Various Chemistry Research Topics ; Nanotechnology research and applications ; Advanced Physical and Chemical Molecular Interactions
Authors: Petro Kyrychok | Dmytro Paliukh
Source: Eastern-European Journal of Enterprise Technologies (article, 2025-06-27)
Field: Materials Science — General Materials Science

Construction of a physical-mechanical model of reinforcing microrelief formation on profiled strips made of AISI 1005 and AISI 347 steels considering surface topology This study’s object is the process that forms a strengthening microrelief on the surface of profiled folding plates made of AISI 1005 and AISI 347 steels through localized indentation using a spherical indenter made of a diamond-based composite material. The principal hypothesis of the study posits that the implementation of a controlled surface texturing process enables the formation of a stable microrelief with predefined geometric characteristics. Achieving this requires establishing the regularities of microrelief formation depending on the physical and mechanical properties of the material, the geometry of the indenter, and the parameters of the contact interaction. A physical and mechanical model of the contact interaction between the indenter and the metallic plate has been built. The results of the analytical modeling were validated through profilometric measurements and 3D visualizations, which revealed differences in the depth and nature of deformation between AISI 1005 and AISI 347. The AISI 1005 steel exhibited higher plasticity and a greater tendency toward deep deformation, whereas AISI 347 demonstrated superior stability in the relief geometry. An evaluation of surface roughness parameters (Ra, Rz, Rmax) indicated that the AISI 347 steel provides better reproducibility of the strengthening effect, with average Ra and Rz values being 2–2.5 times lower than those of AISI 1005. The correlation analysis of microrelief parameters revealed a strong relationship between Ra and Rz values, with a correlation coefficient ranging from 0.93 to 0.96. This finding confirms the stability of the microrelief formation mechanism and justifies the use of AISI 347 steel in combination with a Ø3.5 mm indenter. The results of this study can be applied for manufacturing folding elements with enhanced wear resistance and geometric stability under cyclic loading conditions STRIPS ; Surface (topology) ; Topology (electrical circuits) ; Structural engineering ; Materials science ; Mechanical engineering ; Engineering ; Composite material ; Geometry ; Mathematics ; Electrical engineering Material Properties and Applications ; Polymer Science and Applications ; Engineering Technology and Methodologies