jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Lorenzo Lance David | Moganavelli Singh
Source: Pharmaceuticals (article, 2025-12-30)
Field: Materials Science — Biomaterials

Functionalized Core/Shell Gold-Palladium Bimetallic Nanoparticles in Transferrin-Targeted Dual-Drug Delivery in a Cervical Cancer Cell Model <b>Background/Objectives:</b> Research on noble metal nanoparticles (NPs) has increased over the past three decades, with advancements in synthesis techniques refining their physicochemical characteristics, including size, shape, and surface chemistry. Bimetallic NPs (BNPs) offer synergistic properties contributed by both metals. Gold (Au) and palladium (Pd) NPs possess low toxicity, high biocompatibility and loading, ease of synthesis and surface modification. Doxorubicin (DOX) and 5-fluorouracil (5-FU) are potent chemotherapeutic drugs but are rapidly metabolised in the body, producing severe side effects, limiting their use. Hence, innovative strategies to mitigate this is needed. <b>Methods:</b> In this study, AuPd NPs in a core-shell formation were chemically synthesized. The AuPd NPs were conjugated to 5-FU and DOX-encapsulated CS complexes and decorated with the targeting moiety transferrin (Tf). <b>Results:</b> Transmission electron microscopy and nanoparticle tracking analysis confirmed that the BNPs were spherical, with an average size of 73.4 nm. Functionalized BNPs were able to encapsulate more than 70% of 5-FU and DOX, resulting in a controlled drug release profile at pH 4.2. Cytotoxicity levels in human cancer cells, HeLa (cervical carcinoma) and MCF-7 (breast adenocarcinoma), as well as in non-cancer HEK293 (embryonic kidney) cells, revealed that the Tf-targeted nanocomplexes were HeLa cell-specific, with no significant cytotoxicity in the HEK293 cells. Tf-mediated cellular uptake was confirmed by receptor competition studies in the HeLa cells. Apoptosis and oxidative stress analysis confirmed cell death by apoptosis, consistent with the action of 5-FU and DOX. <b>Conclusions:</b> This study highlighted the potential of this BNP-nanocomplex as a suitable vehicle for drug delivery. HeLa ; Cytotoxicity ; Biocompatibility ; Doxorubicin ; Drug delivery ; Bimetallic strip ; Nanoparticle ; Targeted drug delivery ; Cancer cell Nanoparticle-Based Drug Delivery ; Metal complexes synthesis and properties ; Cancer Research and Treatment
Authors: Abhishek Nayak | Shanon Viegas | Nithya Rajagopal | Adrian Marcel Rodrigues | Harshini Dasari | Nethaji Sundarabal
Source: Materials Advances (article, 2025-01-01)
Field: Chemistry — Analytical Chemistry

Exploring metal nanocomposites for asphaltene removal: the role of Cu-BTC, CoMn <sub>2</sub> O <sub>4</sub> and K-OMS-2 in the adsorption and oxidation of asphaltenes Asphaltenes, the most polar and complex class of compounds in petroleum crude oils, pose significant challenges in refining processes due to their tendency to precipitate, causing fouling, clogging, and corrosion in pipelines and reactors. Asphaltene ; Nanocomposite ; Adsorption ; Metal ; Chemical engineering ; Materials science ; Inorganic chemistry ; Chemistry ; Metallurgy ; Organic chemistry ; Nanotechnology Petroleum Processing and Analysis ; Enhanced Oil Recovery Techniques ; Surfactants and Colloidal Systems
Authors: M. H. N. Revon | Namal Priyantha
Source: Research Square (preprint, 2025-10-14)
Field: Materials Science — Materials Chemistry

Superior Corrosion Inhibition Activity of CaO Nanoparticles Synthesized from Natural Sources toward Grade 202 Stainless-steel in Chloride-rich Media Corrosion ; Tafel equation ; Calcination ; Passivation ; Nanoparticle ; Metal ; Oxide Magnesium Oxide Properties and Applications ; Corrosion Behavior and Inhibition ; Metal and Thin Film Mechanics
Authors: F. M. Mohamed | Mohamed R. El‐Aassar | B. Y. Eweida | Aboubakr M. Abdullah | Hesham Hamad | M. F. Alrakshy | M. Abdel Rafea | Randa E. Khalifa
Source: Applied Water Science (article, 2025-07-12)
Field: Materials Science — Biomaterials

Surface functionalization of cellulose nanocrystals derived from waste newspaper for highly efficient Mn (VII) sorption Abstract This study aims to produce functionalized cellulose nanocrystals (FCNCs) by preparing and functionalizing cellulose nanocrystals (CNCs) from eco-friendly newspapers utilizing a straightforward two-step reaction with an anionic polymer (poly hydrex 6161). FCNCs' structure is described using FTIR, XRD, and SEM. A pseudo-second-order model was used to describe the sorption kinetics of Mn(VII) onto FCNCs, and the results of the linear and nonlinear regression analyses agreed well (R2 &gt; 0.999). Additionally, a number of intervening diffusion types, including intra-particle diffusion, were linked to the regulating phase in the Mn(VII) sorption process. The linear versions of the Freundlich, DR, and Langmuir isotherms were also used to examine the Mn(VII) equilibrium data; the results showed that the Langmuir fits the data better, with an R2 value of 0.9981. This validates the uniform properties of Mn(VII) sorption on the surface of FCNCs with exceptional removal capacities (qmax = 384.615) in both linear and nonlinear modes, in an orderly mode. The spontaneous and endothermic nature of the Mn(VII) sorption process at 288–328 K was confirmed by the thermodynamic parameters ΔH°, ΔS°, and ΔG°. On the other hand, the E value of 1461 kJ mol −1 according to D-R isotherm calculation, which was greater than 8 kJ mol −1 , indicated chemisorption. To ascertain the adsorption mechanism on the FCNCs, techniques such as ion exchange, pore filling, complexation interaction, and electrostatic interaction can be employed. The hybrid FCNCs were able to easily execute at least six adsorption–desorption recycles. The hybrid composite's unique characteristics make it a very promising enhanced adsorbent with great promise for heavy metal removal in wastewater treatment on an industrial scale. Sorption ; Surface modification ; Cellulose ; Nanocrystal ; Chemical engineering ; Newspaper ; Materials science ; Chemistry ; Nanotechnology ; Waste management ; Organic chemistry ; Adsorption ; Engineering ; Business Advanced Cellulose Research Studies ; Adsorption and biosorption for pollutant removal ; Extraction and Separation Processes
Authors: Paunka Vassileva | Dimitrinka Voykova | Diana Kichukova | Tsvetomila Lazarova | Genoveva Atanasova | Daniela Kovacheva | Ivanka Spassova
Source: Materials (article, 2025-02-15)
Field: Chemistry — Organic Chemistry

A Highly Efficient Graphene-Based Material for the Removal of Cationic Dyes from Aqueous Solutions Graphene materials and their derivatives have shown promising capabilities in removing anionic and cationic dyes from wastewater. The present study aims at the synthesis of graphene-based material with a high specific surface area and evaluates its use as an adsorbent for removing toluidine blue and methyl violet from aqueous solutions. The physicochemical characterization of the adsorbent before and after dye adsorption is made by XRD, Raman spectroscopy, SEM, TEM, nitrogen physisorption, TG-DTA, and XPS. The influence of the solution's pH, contact time, dye concentration, and temperature on the adsorption efficiency is investigated. The adsorbent demonstrated high adsorption capacity towards toluidine blue (265.2 mg.g<sup>-1</sup>) and methyl violet (200.4 mg.g<sup>-1</sup>) dyes from water. The adsorption process for both dyes follows the Langmuir model and involves physical rather than chemical interactions. Kinetic parameters were also determined. The adsorption of the studied cationic dyes can be attributed to a combination of mechanisms, including electrostatic interactions, hydrogen bonding, and π-π interactions between the dye molecules and the aromatic structure of reduced graphene oxide. The findings in the present work highlight the possibilities for enhancing graphene-based materials' adsorption capabilities. Graphene ; Aqueous solution ; Cationic polymerization ; Materials science ; Chemical engineering ; Nanotechnology ; Chemistry ; Polymer chemistry ; Organic chemistry Nanomaterials for catalytic reactions ; Adsorption and biosorption for pollutant removal ; Graphene and Nanomaterials Applications
Authors: Yanni Xuan | Kun Yu | Hong Tian | Zhangmao Hu | Wei Zhang | Yanshan Yin | Haitao Gao | Qingbo Yu
Source: Molecules (review, 2025-04-08)
Field: Materials Science — Materials Chemistry

Recent Advances in Materials, Synthesis, and Reaction Model of Particle Adsorbent for Flue Gas Desulfurization Particle adsorbents have gained significant traction in flue gas desulfurization applications, primarily attributed to their high structural homogeneity and large specific surface area. To address the multifaceted requirements of industrial sectors regarding the structural configurations and physicochemical properties of particle adsorbents while promoting sustainable manufacturing practices, this study systematically evaluates and critically appraises contemporary advancements in particle desulfurizing agent technologies. The synthesis of these findings establishes a theoretical framework to facilitate technological innovation and industrial progress within the particle desulfurizer domain. The research systems of particle adsorbents, encompassing active components, inert carriers, preparation methodologies, and gas-solid reaction models, were comprehensively reviewed. The advantages and current limitations of these systems were then systematically summarized. Finally, the fundamental principles and research trajectories in the application fields of distinct particle adsorbent research systems were elucidated. An analysis of the developmental trends indicated that enhancing the utilization efficiency of active components and improving the cyclic stability of adsorbents remained critical engineering challenges. It is posited that the pursuit of high reaction activity, thermal stability, mechanical strength, and superior anti-aggregation/sintering performance constitutes key directions for the advancement of particle adsorbents in China's flue gas desulfurization industry. Flue-gas desulfurization ; Adsorption ; Flue gas ; Waste management ; Particle (ecology) ; Chemistry ; Chemical engineering ; Process engineering ; Materials science ; Environmental science ; Organic chemistry ; Engineering Catalytic Processes in Materials Science ; Industrial Gas Emission Control ; Catalysis and Hydrodesulfurization Studies
Authors: Elżbieta Grządka | E. Godek | Jakub Matusiak | Urszula Maciołek | Małgorzata Wasilewska
Source: ChemPlusChem (article, 2025-05-20)
Field: Materials Science — Biomaterials

Adsorption Mechanisms of Cellulose Derivatives with Different Chemical Nature on Bentonite ‐ pH Perspective The goal of this study is to answer the question of how pH influences the adsorption behavior of cellulose derivatives with different chemical natures (cationic cellulose-AHCE; nonionic hydroxyethyl cellulose, and anionic carboxymethyl cellulose) on the surface of the natural adsorbent bentonite-nanoclay N-HB. The diversity of polysaccharide adsorption is investigated, the mechanisms of this process are determined, and the adsorption layer structure as well as the stability of the systems are characterized. The studies are carried out by UV-vis spectrophotometry, Fourier transform infrared, X-ray diffraction, scanning electron microscopy-electron dispersive spectroscopy, X-ray photoelectron spectroscopy, zeta potential, and thermogravimetric analysis. Apart from the cognitive element, the results obtained have the potential to find practical applications in water purification and in the production of stable colloidal suspensions in cosmetics. Adsorption ; Cellulose ; Zeta potential ; Carboxymethyl cellulose ; Bentonite ; Thermogravimetric analysis ; Chemistry ; Cationic polymerization ; Chemical engineering ; Ionic strength ; Ionic liquid ; Organic chemistry ; Inorganic chemistry ; Nanoparticle ; Catalysis ; Sodium ; Aqueous solution Advanced Cellulose Research Studies ; Polymer Nanocomposites and Properties ; Hydrogels: synthesis, properties, applications
Authors: Kelechi E Onwuka | Ahamefula A. Ahuchaogu | Okechukwu Atasie | Victor Oguike | Akachi C Nwosu | Nkemakolam B Nwosu | James O Nwagba
Source: Acta Technica Jaurinensis (article, 2025-06-21)
Field: Materials Science — Biomaterials

Comparative Adsorption of Ibuprofen and Ciprofloxacin from Aqueous Solution Using Natural Bentonite Clay: Experimental and DFT Study This Study examines the adsorption characteristics of ibuprofen (IBP) and ciprofloxacin (CIP) onto bentonite (BT) in aqueous medium. To investigate surface properties, SEM, FTIR and XRD techniques were used to characterize the bentonite applied as adsorbent. The results confirmed the properties of typical bentonite clay as acceptable. Batch adsorption studies were conducted under different adsorption experimental conditions. The outcome indicated that pH, initial IBP/CIP concentration, adsorbent dosage, contact time and temperature greatly influenced IBP/CIP removal by BT in aqueous medium. Adsorption equilibrium was attained after 240 minutes of contact time for both IBP and CIP. The pseudo first order, pseudo second order, and intraparticle diffusion kinetic models were utilized to describe the kinetic data, while the Langmuir, Freundlich, and Temkin isotherm models were fitted to the equilibrium data. Results obtained from kinetic and isotherm studies showed that both the kinetic and equilibrium data were efficiently described by the pseudo second order kinetic model and Freundlich isotherm model for both pharmaceuticals respectively, as evidenced by correlation coefficients (R²) exceeding 0.98 and lower chi-square (χ²) values observed. Thermodynamic analysis indicated that the removal of IBP/CIP from aqueous solution by BT is spontaneous, endothermic, and characterized by increased disorder. Analysis from Density functional theory (DFT) was incorporated into experimental findings in other to gain clarity on distinctive characteristics of IBP/CIP adsorption. Greater chemical molecular reactivity, lower water solubility, decreased steric hindrance effects, as well as greater hydrophobicity, were factors mostly responsible for the improved ibuprofen and ciprofloxacin adsorption by bentonite. Adsorption ; Freundlich equation ; Bentonite ; Aqueous solution ; Chemistry ; Langmuir ; Langmuir adsorption model ; Nuclear chemistry ; Chemical engineering ; Organic chemistry Clay minerals and soil interactions ; Adsorption and biosorption for pollutant removal ; Pharmaceutical and Antibiotic Environmental Impacts
Authors: Carlos Arauz-Moreno | Keyvan Piroird | Élise Lorenceau
Source: Physical review. E (article, 2025-07-03)
Field: Materials Science — Polymers and Plastics

From champagne to confined polymer: Natural and artificial bubble nucleation In this study, we present an experimental work on bubble nucleation and growth using a model system comprised of viscoelastic polyvinyl butyral confined in a Hele-Shaw cell geometry that is decompressed at elevated temperatures. The appearance and growth of bubbles are connected to the temperature-induced shift in chemical equilibrium experienced simultaneously by two gases present in the bulk. The latter becomes simultaneously oversaturated with water vapor and slightly undersaturated in air. Our bubbles grow with various shapes and sizes depending on the initial morphology of the nucleus or the presence of neighboring bubbles. For large nuclei, bubbles grow anisotropically because of contact line pinning. The likelihood of nucleation is related to the amount of water dissolved in the bulk and the imposed temperature. Counterintuitively, the number of nuclei whence a bubble can grow is inversely correlated with said temperature. In an analogy with champagne, we show that nucleation can either be natural, at trapped fibers or dust particles, or artificial, at crenels we purposefully made in the glass surface. Our results indicate that the growth rate of bubbles can be impacted by the nucleation mechanism. Nucleation ; Bubble ; Polymer science ; Natural (archaeology) ; Polymer ; Materials science ; Natural polymers ; Chemical engineering ; Chemistry ; Composite material ; Physics ; Engineering ; Mechanics ; History ; Archaeology ; Organic chemistry Polymer Foaming and Composites ; Pickering emulsions and particle stabilization
Authors: Rahul Ranjan | Chandra Kant | Prodyut Dhar
Source: Sustainable Food Technology (article, 2025-10-03)
Field: Materials Science — Biomaterials

Multifunctional cellulose phosphate-based food packaging films from biomass: structure–function relationship and environmental assessment studies Sugarcane bagasse (SB), a globally abundant agricultural residue, is often discarded through landfilling or open burning, though it holds significant potential for conversion into value-added phosphorylated gels and films. Cellulose ; Food packaging ; Environmental impact assessment ; Bagasse ; Life-cycle assessment ; Agriculture Advanced Cellulose Research Studies ; Nanocomposite Films for Food Packaging
Authors: Megha Goyal | M.P.S. Chawla | Kulwant Singh | Nitu Bhatnagar
Source: Journal of Applied Polymer Science (article, 2025-06-04)
Field: Materials Science — Electronic, Optical and Magnetic Materials

Fabrication and Characterization of Coin Cell Supercapacitor Device Using <scp>PEDOT:PSS/MgO</scp> Polymer Nanocomposite as Active Material ABSTRACT Poly(3,4‐ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS)/magnesium oxide (MgO) polymer nanocomposites were synthesized and evaluated as active materials for energy storage applications. The composite electrodes exhibited a high specific capacitance of 121 F g −1 at a scan rate of 10 mV s −1 in 2 M KOH electrolyte, demonstrating excellent electrochemical performance. The device achieved a coulombic efficiency of 99% of its initial capacitance after 800 galvanostatic charge–discharge (GCD) cycles at 0.2 A g −1 . Additionally, it displayed an energy density of 1.3 Wh kg −1 and a power density of 5514 W kg −1 , which are competitive with state‐of‐the‐art supercapacitor materials. The Electrochemical Impedance Spectroscopy (EIS) spectra reveal the low internal ( R s = 2.29 Ω) and charge transfer resistance ( R ct = 390 μΩ) which suggest its higher conductivity. A symmetric coin cell supercapacitor device was fabricated, achieving a working potential of 3.04 V and successfully powering an LED, showcasing its real‐world applicability. This study highlights the potential of PEDOT:PSS/MgO nanocomposites as efficient, cost‐effective, and scalable materials for next‐generation energy storage devices. PEDOT:PSS ; Nanocomposite ; Fabrication ; Materials science ; Supercapacitor ; Characterization (materials science) ; Polymer ; Composite material ; Chemical engineering ; Polymer chemistry ; Nanotechnology ; Capacitance ; Electrode ; Chemistry Supercapacitor Materials and Fabrication ; Advancements in Battery Materials ; Advanced Battery Materials and Technologies
Authors: Sergio Ayala‐Mar | Oju Jeon | Pedro Chacón-Ponce | José González‐Valdez | Eben Alsberg
Source: bioRxiv (Cold Spring Harbor Laboratory) (preprint, 2025-04-08)
Field: Materials Science — Biomaterials

Photocrosslinkable and biodegradable hydrogels for the controlled delivery of exosomes Abstract Local and controlled delivery of exosomes using hydrogels can improve the efficacy of exosome-based therapeutics. Hydrogels based on oxidized and methacrylated alginate (OMA) can be produced through photocrosslinking and exhibit controllable degradability. The degradation properties of OMA hydrogels can be tailored by varying the alginate oxidation degree, which is advantageous for exploring new therapeutic strategies. Here, we prepared photocrosslinkable, biodegradable, cytocompatible, and tunable alginate hydrogels for exosome delivery. We synthesized OMA with different degrees of alginate oxidation to generate OMA hydrogels that undergo both rapid and slow degradation. The degradation rate, swelling ratio and mechanical stability of the OMA hydrogels were investigated. Likewise, we examined exosome release rate and kinetics. The cytocompatibility and functionality of these systems were confirmed. Increasing the alginate oxidation degree greatly enhanced the degradation of OMA hydrogels. Rapid degradation correlated with accelerated exosome release, while slow degradation correlated with enhanced exosome retention. Physicochemical properties including the rheological behavior and swelling also influenced the exosome release rate. Kinetic equation fits showed that the Korsmeyer-Peppas model can be used to describe the release process. These findings demonstrate that OMA hydrogels are suitable delivery carriers for the controlled release of exosomes and highlight the potential use of this technology in applications that depend on either rapid or slow exosome delivery and the temporary presence of the hydrogel, including tissue engineering, wound healing and localized and targeted drug delivery. Microvesicles ; Self-healing hydrogels ; Chemistry ; Polymer chemistry ; Biochemistry Electrospun Nanofibers in Biomedical Applications ; Extracellular vesicles in disease ; Silk-based biomaterials and applications
Authors: P. Nagabhushanam | Roopa Bose | AswathySivanand
Source: Journal of Radioanalytical and Nuclear Chemistry (article, 2025-09-06)
Field: Chemistry — Inorganic Chemistry

Study of uranium sorption from aqueous solution using D2EHPA impregnated chitin as a biodegradable natural support A novel adsorbent was synthesized by grafting Di-(2-ethylhexyl) phosphoric acid (D2EHPA) onto chitin, enhancing its affinity for uranium U(VI) from aqueous solutions. Batch experiments to study the effect of pH, contact time, adsorbent dose, competing ions, and volume revealed rapid adsorption equilibrium within 60 min, the mechanism of adsorption being governed by both physisorption and chemisorption and intraparticle diffusion as the rate-limiting step. The Langmuir isotherm model indicated a remarkable maximum adsorption capacity of 555 mg/g. The synergistic presence of –PO(OH), –NH2, and –OH groups enabled potent and selective complexation with U(VI). The adsorbent exhibited excellent reusability through multiple sorption–desorption cycles. Sorption ; Chitin ; Aqueous solution ; Uranium ; Chemistry ; Nuclear chemistry ; Chemical engineering ; Chitosan ; Adsorption ; Organic chemistry ; Materials science ; Metallurgy ; Engineering Radioactive element chemistry and processing ; Extraction and Separation Processes ; Chemical Synthesis and Characterization