jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Alain M. Bapolisi | Steffen Tank | Anne‐Catherine Lehnen | Antje Stindt | Rujuta Athavale | Jan Kurki | Sany Chea | Sophia Rosencrantz | Ruben R. Rosencrantz | Katja M. Arndt | Matthias Hartlieb
Source: Advanced Materials Interfaces (article, 2025-07-27)
Field: Chemistry — Organic Chemistry

Sugars in Antimicrobial Polymers – The Impact of Sugar‐Lectin Binding in Membrane Interaction of Cationic Glycopolymers Abstract Membrane‐active antimicrobial polymers (APs) are promising alternatives for treating infectious diseases as they are less susceptible to antimicrobial resistance development. However, their non‐specific cytotoxicity limits their clinical application. One interesting strategy to improve cytocompatibility is the incorporation of sugar units into APs. This approach takes advantage of specific interactions between sugars and protein receptors, such as lectins, on the surface of bacteria, potentially allowing for discrimination between different bacterial types. However, there is limited research on how sugar addition to cationic APs affects their selectivity and interactions with lectins. Herein, a library of acrylamide‐based cationic glycopolymers is synthesized by a xanthate‐supported photo‐initiated Reversible Additon‐Fragmentation chain Trasnfer (XPI‐RAFT) polymerization. Diverse sugars are added to this cationic scaffold by either chain extension with glycomonomers (based on fucose, glucose, mannose, and polyhydroxy acrylamide) or simply by reductive amination (lactose and melibiose). Various analytical techniques are used to probe the interaction of (glyco)polymers with bacteria, membrane models, and lectins. In general, (glyco)polyhydroxy incorporation proves to reduce the hydrophobicity of the cationic APs and consequently enhances hemocompatibility while maintaining the antimicrobial activity. Although sugar‐protein‐specific recognition may contribute to selectivity, the results demonstrate that electrostatic interaction predominantly drives the binding efficacy of cationic glycopolymers to bacterial membranes. Cationic polymerization ; Materials science ; Lectin ; Polymer ; Antimicrobial ; Sugar ; Membrane ; Polymer science ; Organic chemistry ; Polymer chemistry ; Biochemistry ; Chemistry ; Composite material Antimicrobial agents and applications ; Antimicrobial Peptides and Activities ; Biopolymer Synthesis and Applications
Authors: Gréta Törős | Áron Béni | Andrea Balla Kovács | Dávid Semsey | Aya Ferroudj | József Prokisch
Source: Pharmaceutics (article, 2025-04-30)
Field: Materials Science — Materials Chemistry

Production of Myco-Nanomaterial Products from Pleurotus ostreatus (Agaricomycetes) Mushroom via Pyrolysis <b>Background:</b> The study aimed to develop a sustainable method for producing myco-nanomaterials, particularly fluorescent carbon nanodots (CNDs), from freeze-dried <i>Pleurotus ostreatus</i> (Agaricomycetes) mushroom powder via pyrolysis. The goal was to investigate how pyrolysis conditions affect CND characteristics and their potential antimicrobial properties. Mushroom powder was pyrolyzed at temperatures ranging from 150 to 240 °C. The resulting products were analyzed for yield, molecular weight, fluorescence intensity, and estimated CND concentration in relation to the carbon-to-nitrogen (C/N) ratio. Antibacterial activity was tested against <i>Escherichia coli</i> and <i>Staphylococcus epidermidis</i>. Product yield decreased from 13.20% at 150 °C to 0.80% at 240 °C. Molecular weight peaked at 200 °C (623.20 kDa), while maximum fluorescence intensity (739.40 A.U.) was observed at 210 °C. A strong positive correlation (R<sup>2</sup> = 0.72) was found between the C/N ratio and estimated CND concentration. Antimicrobial testing revealed notable inhibition of <i>E. coli,</i> associated with higher fluorescence intensity and CND content. Pyrolyzed <i>P. ostreatus</i> mushroom powder offers a promising, eco-friendly platform for producing luminescent, carbonaceous nanomaterials with antibacterial potential. These non-purified, myco-derived nanomaterials may contribute to green nanotechnology development and antimicrobial strategies. Pleurotus ostreatus ; Agaricomycetes ; Mushroom ; Chemistry ; Pleurotus ; Food science ; Biology ; Botany ; Basidiomycota Carbon and Quantum Dots Applications ; Nanoparticles: synthesis and applications
Authors: Florian Tondock | David G. Nash | Cathleen Hudziak | Kai Ludwig | Marie Weinhart
Source: Polymer Chemistry (article, 2025-01-01)
Field: Chemistry — Organic Chemistry

Design and synthesis of amphiphilic statistical copolymers forming unimeric micelles with thermoresponsive behaviour in the physiological range A crucial aspect of drug development is designing carriers that efficiently solubilise therapeutic agents while ensuring stability, minimising cytotoxicity, and enabling targeted delivery. Copolymer ; Amphiphile ; Micelle ; Range (aeronautics) ; Chemistry ; Materials science ; Polymer chemistry ; Chemical engineering ; Organic chemistry ; Polymer ; Engineering ; Composite material Advanced Polymer Synthesis and Characterization ; Surfactants and Colloidal Systems ; Photopolymerization techniques and applications
Authors: Magdalena Błachnio | Małgorzata Zienkiewicz-Strzałka | Anna Deryło‐Marczewska
Source: International Journal of Molecular Sciences (article, 2025-09-22)
Field: Materials Science — Materials Chemistry

Mesoporous Silicas of Well-Organized Structure: Synthesis, Characterization, and Investigation of Physical Processes Occurring in Confined Pore Spaces Mesoporous silica materials with well-organized architectures were synthesized using a series of Pluronic PE-type triblock copolymers (PE6800, PE9200, PE9400, PE10500) as structure-directing agents under acidic conditions. The study aimed to elucidate the impact of synthesis parameters-copolymer type, presence of a swelling agent, 1,3,5-trimethylbenzene, aging temperature, and silica precursor-on the structural, textural, and functional properties of the resulting mesocellular foam materials. Characterization by Nitrogen Adsorption/Desorption, Transmission Electron Microscopy, X-ray Diffraction, and Small-angle X-ray Scattering revealed that structural ordering and pore morphology are significantly influenced by the EO/PO ratio of the copolymers and the use of the expander. Materials synthesized with PE9400 and PE10500 in the presence of a swelling agent exhibited highly uniform bottle-shaped mesopores with increased surface area and pore volume. Thermal behavior studied via Differential Scanning Calorimetry indicated a correlation between pore size and melting point depression of confined water, consistent with the Gibbs-Thomson effect. Adsorption capacity and kinetics for methylene blue varied significantly with pore structure, with materials possessing narrow mesopores showing superior dye uptake, and materials with larger mesopores and open-pore architecture exhibiting faster adsorption rates. This work demonstrates the tunability of mesoporous silica structure through precise control of synthesis conditions and highlights its potential in applications involving adsorption and phase phenomena in confined pore systems. Mesoporous material ; Differential scanning calorimetry ; Swelling ; Mesoporous organosilica ; Copolymer ; Adsorption ; Melting-point depression ; Mesoporous silica ; Specific surface area Mesoporous Materials and Catalysis ; Covalent Organic Framework Applications ; Analytical Chemistry and Chromatography
Authors: G. N. Lipunova | Emiliya V. Nosova | Valery N. Charushin
Source: Molecules (review, 2025-08-27)
Field: Chemistry — Organic Chemistry

Quinazolines [a]-Annelated by Five-Membered Heterocycles: Synthesis and Biological Activity This review covers article and patent data obtained mostly within the period 2013-2024 on the synthesis and biological activity of quinazolines [<i>a</i>]-annelated by five-membered heterocycles. Pyrrolo-, (iso)indolo-, pyrazolo-, indazolo-, (benz)imidazo-, (benz)thiazolo-, and triazolo- [<i>a</i>]quinazoline systems have shown multiple potential activities against numerous targets. We highlight that most research efforts are directed to design of anticancer, antibacterial, anti-inflammatory, and other agents of azolo[<i>a</i>]quinazoline nature. This review emphases both the medicinal chemistry aspects of pyrrolo[<i>a</i>]-, (iso)indolo[<i>a</i>]-, and azolo[<i>a</i>]quinazolines and the comprehensive synthetic strategies of quinazolines annelated at the N(1)-C(2) bond from the perspective of drug development and discovery. Chemistry ; Combinatorial chemistry ; Organic chemistry Quinazolinone synthesis and applications ; Synthesis and Characterization of Heterocyclic Compounds ; Phenothiazines and Benzothiazines Synthesis and Activities
Authors: Chamoni W. H. Rajawasam | Dominik Konkolewicz | C.S. Hartley
Source: ChemSystemsChem (article, 2025-02-04)
Field: Chemistry — Organic Chemistry

Autonomous Changes in Polymer Materials Driven by Chemical Fuels Abstract Time‐dependent properties in polymer materials can be achieved through coupling to out‐of‐equilibrium chemical fuel reactions that mimic biological processes. Through transient changes in bonding in polymers, transient gelation, changes in mechanical stiffness, swelling, self‐healing, or self‐assembly can be achieved. Recent advances in these categories are discussed. These out‐of‐equilibrium behaviors enable applications ranging from smart adhesives to actuators for soft robotics. However, challenges remain, including waste accumulation, bio‐compatibility, and achieving functionally useful performance. Addressing these issues is essential for advancing the practical use of chemically driven polymer materials and unlocking their full potential for future technologies. Polymer ; Materials science ; Polymer science ; Chemical engineering ; Process engineering ; Environmental science ; Biochemical engineering ; Nanotechnology ; Engineering ; Composite material Advanced Polymer Synthesis and Characterization ; Polymer composites and self-healing ; Polymer Surface Interaction Studies
Authors: Hui Wang
Source: Chemical Communications (article, 2025-01-01)
Field: Materials Science — Electronic, Optical and Magnetic Materials

A repertoire of gold-based nanostructures with integrated optical and catalytic tunabilities Au nanoparticles exhibit geometry-dependent optical characteristics dictated by localized plasmon resonances and intriguing catalytic properties intimately tied to their atomic-level surface structures. While the dimensions of well-performing plasmon resonators typically range from tens of nanometers to submicrons, heterogeneous catalysis usually entails the use of much smaller nanoparticulate Au catalysts in the sub-5 nm size regime. Due to such a size gap, merging optical and catalytic tunabilities in a single Au nanoparticle has been a challenging task. In this feature article, I review several paradigm-shifting strategies for integrating tunable optical and catalytic properties within single Au-based nanostructures that are experimentally realizable. These strategies include nanoscale surface roughening of Au nanoparticles, creation of nanoporosity inside Au nanoparticles, facet control of anisotropic Au nanostructures, growth of Au nanocrystals with intrinsic structural chirality, and alloying Au with other metal elements in nanoparticles. By going through several case studies, I further elaborate on how the optical and catalytic properties can be judiciously tuned in a selection of dual-functional Au-based nanostructures to enable real-time monitoring of molecular transformations at the catalyst-adsorbate interfaces through <i>in situ</i> plasmon-enhanced spectroscopic measurements and kinetic modulation of catalytic/photocatalytic reactions through optical excitations of plasmonic electron oscillations and interband electronic transitions. Repertoire ; Catalysis ; Nanostructure ; Nanotechnology ; Chemistry ; Materials science ; Physics ; Organic chemistry Gold and Silver Nanoparticles Synthesis and Applications ; Nanocluster Synthesis and Applications ; Catalytic Processes in Materials Science
Authors: Kaysa Sekhavati | Vikas Sharma | Ashok Keerthi
Source: Materials Advances (review, 2025-01-01)
Field: Materials Science — Polymers and Plastics

Solution-phase synthesis of graphene nanoribbons: a review on polymerization strategies This review discusses solution-phase synthesis of graphene nanoribbons via various polymerization methods, emphasizing Scholl-type cyclodehydrogenation and new approaches for edge-engineered nanographenes with tunable electronic properties. Graphene nanoribbons ; Polymerization ; Materials science ; Graphene ; Phase (matter) ; Nanotechnology ; Chemistry ; Polymer ; Composite material ; Organic chemistry Conducting polymers and applications ; Graphene and Nanomaterials Applications ; Supramolecular Self-Assembly in Materials
Authors: Ubaid ur Rahman | Abbas Khan | Asadullah | Muhammad Humayun | Nasrullah Shah | Amal Faleh Alanazi | M. Bououdina
Source: RSC Advances (article, 2025-01-01)
Field: Chemistry — Organic Chemistry

Copper-modified graphene oxide and reduced graphene oxide nanocomposites for the photo-assisted removal of basic blue-3 dye Basic Blue 3 (BB3) dye is a very contaminating substance that poses a substantial risk to human health and the environment. To solve this issue, we synthesized carbon-based materials, such as graphene oxide (GO), reduced graphene oxide (R-GO), and their nanocomposites, which demonstrated exceptional potential for the photo-assisted removal of BB3 dye. Pristine GO and R-GO were synthesized using a modified Hummers' method, while copper (Cu) nanoparticles (NPs) were incorporated through a simple co-precipitation method to boost the photocatalytic performance of the resultant hybrid materials. A detailed characterization of these synthesized nano-materials was performed using several analytical techniques to understand their structural, morphological, and chemical properties. Characterization results confirmed the successful fabrication of the desired hybrid nanocomposites. The photo-assisted removal of BB3 dye using synthesized nano-materials was evaluated under a batch methodology, changing the experimental conditions to optimize BB3 dye removal from wastewater. The results exhibited that Cu@R-GO and Cu@GO nanocomposites exhibited notable photocatalytic performance, accomplishing maximum removal rates of 75.41% and 68.05%, respectively. These values were meaningfully higher than those of R-GO (44.92%) and GO (35.11%) under the same experimental conditions. Furthermore, to increase insights into the degradation mechanism, the experimental data were analyzed using thermodynamic and kinetic models. The results indicate that the Cu@R-GO nanocomposite not only possesses excellent degradation abilities but also displays promising thermodynamic and kinetic parameters for the photo-assisted removal of BB3 dye. The results of our study clearly indicate that the Cu@R-GO nanocomposite as an outstanding candidate for the photocatalytic removal of impurities from wastewater, offering a possible solution for environmental remediation. Graphene ; Oxide ; Nanocomposite ; Graphene oxide paper ; Materials science ; Chemical engineering ; Copper ; Copper oxide ; Nanotechnology ; Chemistry ; Metallurgy Nanomaterials for catalytic reactions ; Graphene and Nanomaterials Applications ; Advanced Nanomaterials in Catalysis
Authors: Sana Kabdrakhmanova | Aigul Kerimkulova | Saule Z. Nauryzova | Kadiran Aryp | Esbol Shaimardan | Anastassiya D. Kukhareva | Nurgamit Kantay | Madiar Beisebekov | Sabu Thomas
Source: Journal of Composites Science (article, 2025-06-18)
Field: Materials Science — Polymers and Plastics

Bentonite-Based Composites in Medicine: Synthesis, Characterization, and Applications One of the most interesting and poorly studied carriers of medicinal substances is the polymer clay composite material (PCCM). Bentonite clays are used in pharmacy for the manufacturing of various dosage forms, as well as in the adsorption of drugs to slow their release. Polymer–clay nanocomposites have demonstrated significantly improved properties compared to pure polymers. A review of recent scientific advances has shown promising results regarding the application of polymer–clay materials in medicine and bioengineering, particularly in the development of carrier sorbents with prolonged action for controlled drug release. As a result, interest in polymer–clay systems is steadily growing and gaining momentum. This paper focuses on the structure and properties of bentonite clays, including their sorption, ion exchange, binding, and rheological properties. The methods for preparing intercalated and exfoliated nanocomposites, such as radical intercalative polymerization in situ on clay surfaces, are reviewed. Furthermore, the improved efficacy and exposure times of PCCMs, combined with their enhanced bactericidal properties, are analyzed for the creation of universal and multifunctional preparations for medical use. Bentonite ; Materials science ; Sorption ; Polymer ; Nanocomposite ; Adsorption ; Characterization (materials science) ; Chemical engineering ; Polymerization ; Composite material ; Polymer science ; Nanotechnology ; Chemistry ; Organic chemistry Polymer Nanocomposites and Properties ; Clay minerals and soil interactions ; Therapeutic Uses of Natural Elements
Authors: Nthabiseng Motshabi | Gaofetoge Gobodiwang Lenetha | Moipone Alice Malimabe | Thandi Patricia Gumede
Source: Polymers (review, 2025-07-16)
Field: Materials Science — Biomaterials

Cellulose Nanofibril-Based Biodegradable Polymers from Maize Husk: A Review of Extraction, Properties, and Applications The environmental impact of petroleum-based plastics has driven a global shift toward sustainable alternatives like biodegradable polymers, including polylactic acid (PLA), polybutylene succinate (PBS), and polycaprolactone (PCL). Yet, these bioplastics often face limitations in mechanical and thermal properties, hindering broader use. Reinforcement with cellulose nanofibrils (CNFs) has shown promise, yet most research focuses on conventional sources like wood pulp and cotton, neglecting agricultural residues. This review addresses the potential of maize husk, a lignocellulosic waste abundant in South Africa, as a source of CNFs. It evaluates the literature on the structure, extraction, characterisation, and integration of maize husk-derived CNFs into biodegradable polymers. The review examines the chemical composition, extraction methods, and key physicochemical properties that affect performance when blended with PLA, PBS, or PCL. However, high lignin content and heterogeneity pose extraction and dispersion challenges. Optimised maize husk CNFs can enhance the mechanical strength, barrier properties, and thermal resistance of biopolymer systems. This review highlights potential applications in packaging, biomedical, and agricultural sectors, aligning with South African bioeconomic goals. It concludes by identifying research priorities for improving compatibility and processing at an industrial scale, paving the way for maize husk CNFs as effective, locally sourced reinforcements in green material innovation. Husk ; Bioplastic ; Materials science ; Biopolymer ; Cellulose ; Polylactic acid ; Polybutylene succinate ; Biodegradable polymer ; Pulp (tooth) ; Pulp and paper industry ; Polymer ; Waste management ; Composite material ; Chemical engineering ; Engineering Advanced Cellulose Research Studies ; biodegradable polymer synthesis and properties ; Electrospun Nanofibers in Biomedical Applications
Authors: Qinzhen Li | Baoyu Huang | Sha Yang | Jinsong Chai | Yong Pei | Manzhou Zhu
Source: Aggregate (article, 2025-12-01)
Field: Materials Science — Materials Chemistry

Conformational Transition‐Triggered Thermosensitive Tautomerization in Gold Nanoclusters for Optical Thermometry ABSTRACT The structural tautomerism of nanoclusters plays an indispensable role in establishing dynamic structure–activity relationship models and designing nanocluster‐based intelligent functional materials, yet precise control of this dynamic process remains challenging. This study proposes a steric‐hindrance‐driven conformational switching strategy, achieving spatial torsion of a Au 1 (SR) 2 motif on Au 24 (SR) 16 nanoclusters. The conformational transition alters spatial proximity and electron cloud density of Au 24 (SR) 16 , thereby modulating reaction kinetics to trigger or inhibit its global structural tautomerism. Crystallographic analysis and density functional theory (DFT) calculations confirm that ligand steric effects and metal–ligand interactions govern the tautomeric pathway. The equilibrium dynamics of this tautomeric system demonstrates pronounced temperature dependence, wherein a mathematical relationship between the absorbance and temperature is established, thus endows it with the function of a nano‐thermometer, showing a temperature measurement error of ≤0.3°C. In addition, this conformational switching strategy is demonstrated to be extensible to other gold nanocluster systems, thereby establishing its broad applicability. This work offers a paradigm for designing functional nanomaterials through dynamic conformational reconstruction. Tautomer ; Nanoclusters ; Density functional theory ; Steric effects ; Nanomaterials ; Conformational change ; Molecular dynamics Nanocluster Synthesis and Applications ; Gold and Silver Nanoparticles Synthesis and Applications ; Advanced Nanomaterials in Catalysis
Authors: Merum Dhananjaya | Misook Kang
Source: Advances in Industrial and Engineering Chemistry (article, 2025-11-08)
Field: Materials Science — Electronic, Optical and Magnetic Materials

From biomass to energy storage: sustainable carbon materials for next-generation supercapacitors Global energy demand continues to grow, and the depletion of fossil fuels, coupled with increasing environmental concerns, underscores the importance of sustainable energy storage solutions. Supercapacitors are promising electrochemical energy storage devices due to their high power density, fast charge–discharge kinetics, and long cycle life. However, the use of conventional fossil-based or hazardous electrode materials limits their sustainability. Biomass-derived carbons (BDCs) offer a renewable, low-cost, and carbon–neutral alternative, with tunable hierarchical porosity, heteroatom doping, and tailored surface chemistry that enhance ion transport, wettability, and electrochemical performance. This review presents a comprehensive overview of recent advances in BDCs for next-generation supercapacitors, covering sources ranging from agricultural residues, fruit and nut peels, and wood to algae and industrial by-products. Synthesis strategies, including pyrolysis, hydrothermal treatment, carbonization, chemical and physical activation, templating, heteroatom doping, and composite formation, are critically discussed in relation to structure–function relationships. Case studies demonstrate the role of BDCs as electric double-layer capacitor hosts, conductive scaffolds, and hybrid electrodes for enhanced energy storage. Key challenges are discussed, including feedstock variability, reproducibility, and the environmental footprints of activation processes. Opportunities are identified in scalable continuous processing, circular economy integration, green activation methods, and hybrid device designs. Finally, standardized metrics, life-cycle and techno-economic assessments, and prototype-scale validations are proposed to accelerate the industrial translation of BDCs into sustainable, high-performance supercapacitor technologies. Supercapacitor ; Energy storage ; Raw material ; Biomass (ecology) ; Renewable energy ; Carbon footprint ; Fossil fuel ; Hazardous waste Supercapacitor Materials and Fabrication ; Catalysis for Biomass Conversion ; Fiber-reinforced polymer composites