jablonkagroup/rise_ai_scientists huggingface dataset:
Authors: Dongjuan Si | Quan‐Lin Li | Yifan Bao | Jingye Zhang | Lu Wang
Source: Angewandte Chemie International Edition (review, 2023-07-22)
Field: Chemistry — Organic Chemistry

Fluorogenic and Cell‐Permeable Rhodamine Dyes for High‐Contrast Live‐Cell Protein Labeling in Bioimaging and Biosensing The advancement of fluorescence microscopy techniques has opened up new opportunities for visualizing proteins and unraveling their functions in living biological systems. Small-molecule organic dyes, which possess exceptional photophysical properties, small size, and high photostability, serve as powerful fluorescent reporters in protein imaging. However, achieving high-contrast live-cell labeling of target proteins with conventional organic dyes remains a considerable challenge in bioimaging and biosensing due to their inadequate cell permeability and high background signal. Over the past decade, a novel generation of fluorogenic and cell-permeable dyes has been developed, which have substantially improved live-cell protein labeling by fine-tuning the reversible equilibrium between a cell-permeable, nonfluorescent spirocyclic state (unbound) and a fluorescent zwitterion (protein-bound) of rhodamines. In this review, we present the mechanism and design strategies of these fluorogenic and cell-permeable rhodamines, as well as their applications in bioimaging and biosensing. Fluorescence ; Rhodamine ; Biosensor ; Cell permeability ; Live cell imaging ; Chemistry ; Biophysics ; Nanotechnology ; Cell ; Small molecule ; Zwitterion ; High contrast ; Fluorescence microscope ; Molecule ; Materials science ; Biochemistry ; Biology Click Chemistry and Applications ; Molecular Sensors and Ion Detection ; Chemical Synthesis and Analysis
Authors: Chinmaya Mutalik | Muhammad Saukani | Muhamad Khafid | Dyah Ika Krisnawati | Widodo Widodo | Rofik Darmayanti | Betristasia Puspitasari | Tsai-Mu Cheng | Tsung‐Rong Kuo
Source: International Journal of Molecular Sciences (review, 2023-06-11)
Field: Materials Science — Materials Chemistry

Gold-Based Nanostructures for Antibacterial Application Bacterial infections have become a fatal threat because of the abuse of antibiotics in the world. Various gold (Au)-based nanostructures have been extensively explored as antibacterial agents to combat bacterial infections based on their remarkable chemical and physical characteristics. Many Au-based nanostructures have been designed and their antibacterial activities and mechanisms have been further examined and demonstrated. In this review, we collected and summarized current developments of antibacterial agents of Au-based nanostructures, including Au nanoparticles (AuNPs), Au nanoclusters (AuNCs), Au nanorods (AuNRs), Au nanobipyramids (AuNBPs), and Au nanostars (AuNSs) according to their shapes, sizes, and surface modifications. The rational designs and antibacterial mechanisms of these Au-based nanostructures are further discussed. With the developments of Au-based nanostructures as novel antibacterial agents, we also provide perspectives, challenges, and opportunities for future practical clinical applications. Nanostructure ; Nanotechnology ; Nanorod ; Nanoclusters ; Materials science ; Antibacterial activity ; Colloidal gold ; Nanoparticle ; Bacteria ; Biology Nanocluster Synthesis and Applications ; Quantum Dots Synthesis And Properties ; Advanced Nanomaterials in Catalysis
Authors: Wenjing Wang | Kongzhao Su | Daqiang Yuan
Source: Materials Chemistry Frontiers (article, 2023-01-01)
Field: Chemistry — Inorganic Chemistry

Porous organic cages for gas separations This review aims to provide a comprehensive overview of the recent advancements made in gas separations utilizing porous organic cages (POCs). Porosity ; Materials science ; Porous medium ; Nanotechnology ; Chemical engineering ; Engineering ; Composite material Metal-Organic Frameworks: Synthesis and Applications ; Covalent Organic Framework Applications ; Membrane Separation and Gas Transport
Authors: Amit Ghosh | Laura Slappendel | Bao‐Nguyen T. Nguyen | Larissa K. S. von Krbek | Tanya K. Ronson | Ana M. Castilla | Jonathan R. Nitschke
Source: Journal of the American Chemical Society (article, 2023-02-08)
Field: Materials Science — Materials Chemistry

Light-Powered Reversible Guest Release and Uptake from Zn<sub>4</sub>L<sub>4</sub> Capsules A strategy for light-powered guest release from a tetrahedral capsule has been developed by incorporating azobenzene units at its vertices. A new Zn<sub>4</sub>L<sub>4</sub> tetrahedral capsule bearing 12 diazo moieties at its metal-ion vertices was prepared from a phenyldiazenyl-functionalized subcomponent and a central trialdehyde panel. Ultraviolet irradiation caused isomerization of the peripheral diazo groups from the thermodynamically preferred <i>trans</i> configuration to the <i>cis</i> form, thereby generating steric clash and resulting in cage disassembly and concomitant guest release. Visible-light irradiation drove cage re-assembly following re-isomerization of the diazo groups to the <i>trans</i> form, resulting in guest re-uptake. A detailed <sup>19</sup>F NMR study elucidated how switching led to guest release: each metal vertex tolerated only one <i>cis</i>-azobenzene moiety, with further isomerization leading to cage disassembly. Chemistry ; Crystallography ; Stereochemistry ; Chemical engineering ; Nanotechnology Luminescence and Fluorescent Materials ; Catalytic Cross-Coupling Reactions ; Supramolecular Chemistry and Complexes
Authors: Xin Yuan | Xiaoling Wu | Jun Xiong | Binhang Yan | Ruichen Gao | Shuli Liu | Min‐Hua Zong | Jun Ge | Wen‐Yong Lou
Source: Nature Communications (article, 2023-09-25)
Field: Chemistry — Inorganic Chemistry

Hydrolase mimic via second coordination sphere engineering in metal-organic frameworks for environmental remediation Enzymes achieve high catalytic activity with their elaborate arrangements of amino acid residues in confined optimized spaces. Nevertheless, when exposed to complicated environmental implementation scenarios, including high acidity, organic solvent and high ionic strength, enzymes exhibit low operational stability and poor activity. Here, we report a metal-organic frameworks (MOFs)-based artificial enzyme system via second coordination sphere engineering to achieve high hydrolytic activity under mild conditions. Experiments and theoretical calculations reveal that amide cleavage catalyzed by MOFs follows two distinct catalytic mechanisms, Lewis acid- and hydrogen bonding-mediated hydrolytic processes. The hydrogen bond formed in the secondary coordination sphere exhibits 11-fold higher hydrolytic activity than the Lewis acidic zinc ions. The MOFs exhibit satisfactory degradation performance of toxins and high stability under extreme working conditions, including complicated fermentation broth and high ethanol environments, and display broad substrate specificity. These findings hold great promise for designing artificial enzymes for environmental remediation. Environmental remediation ; Hydrolase ; Metal-organic framework ; Chemistry ; Nanotechnology ; Environmental science ; Materials science ; Enzyme ; Biology ; Biochemistry ; Ecology ; Contamination ; Organic chemistry Metal-Organic Frameworks: Synthesis and Applications ; Advanced Nanomaterials in Catalysis ; Covalent Organic Framework Applications
Authors: Mohammad Faheem Khan | Mohd Aamish Khan
Source: Future Pharmacology (article, 2023-03-01)
Field: Materials Science — Materials Chemistry

Plant-Derived Metal Nanoparticles (PDMNPs): Synthesis, Characterization, and Oxidative Stress-Mediated Therapeutic Actions In the 21st century, plant-derived metal nanoparticles (PDMNPs) have gained considerable interest because of their tremendous and remarkable potential as therapeutic agents as well as development of less expensive, safer, and easier biomedical equipment. PDMNPs are synthesized from metal salts or oxides by using plant extracts because plants have diversified bioactive compounds that can act as reducing and stabilizing agents at the time of nanoparticle synthesis. Besides, PDMNPs take advantages over the nanoparticles synthesized by other methods because of their low cost, environmental friendliness, and sustainability. The present review explains the synthesis of PDMNPs, their characterization techniques, and oxidative stress-mediated pharmacological effects. The mode of actions for antioxidant, antimicrobial, and anticancer properties has also been critically explored. Due to the plethora of data on plant-derived nanoparticles and their pharmacological properties, we have highlighted PDMNPs’ shape, size, metals of use, and experimental findings regarding their antioxidant, anti-microbial, and anticancer properties in a tabulated form for studies conducted in the last five years, from 2018 to 2022. Because of our review study, we, herein, contemplate that the scientific community as a whole will get a greater comprehension of PDMNPs and their numerous therapeutic applications in a single window. Oxidative stress ; Nanoparticle ; Nanotechnology ; SAFER ; Characterization (materials science) ; Antimicrobial ; Biochemical engineering ; Combinatorial chemistry ; Chemistry ; Materials science ; Computer science ; Biochemistry ; Engineering ; Organic chemistry Nanoparticles: synthesis and applications ; Moringa oleifera research and applications
Authors: Pritam Roychowdhury | Samya Samanta | Hao Tan | David C. Powers
Source: Organic Chemistry Frontiers (article, 2023-01-01)
Field: Chemistry — Organic Chemistry

<i>N</i>-Amino pyridinium salts in organic synthesis C-N bond forming reactions hold immense significance to synthetic organic chemistry. In pursuit of efficient methods for the introduction of nitrogen in organic small molecules, myriad synthetic methods have been developed, and methods based on both nucleophilic and electrophilic aminating reagents have received sustained research effort. In response to continued challenges - the need for substrate prefunctionalization, the requirement for vestigial <i>N</i>-activating groups, and the need to incorporate nitrogen in ever more complex molecular settings - the development of novel aminating reagents remains a central challenge in method development. <i>N</i>-aminopyridinums and their derivatives have recently emerged as a class of bifunctional aminating reagents, which combine <i>N</i>-centered nucleophilicity with latent electrophilic or radical reactivity by virtue of the reducible N-N bond, with broad synthetic potential. Here, we summarize the synthesis and reactivity of <i>N</i>-aminopyridinium salts relevant to organic synthesis. The preparation and application of these reagents in photocatalyzed and metal-catalyzed transformations is discussed, showcasing the reactivity in the context of bifunctional platform and its potential for innovation in the field. Chemistry ; Pyridinium ; Organic synthesis ; Reagent ; Reactivity (psychology) ; Combinatorial chemistry ; Organic chemistry ; Catalysis Catalytic C–H Functionalization Methods ; Synthesis and Catalytic Reactions ; Cyclopropane Reaction Mechanisms
Authors: Resego Phiri | Sanjay Mavinkere Rangappa | Suchart Siengchin | Dragan Marinković
Source: Facta Universitatis Series Mechanical Engineering (article, 2023-12-16)
Field: Materials Science — Polymers and Plastics

AGRO-WASTE NATURAL FIBER SAMPLE PREPARATION TECHNIQUES FOR BIO-COMPOSITES DEVELOPMENT: METHODOLOGICAL INSIGHTS In today's engineering industries, there is a growing focus on sustainable and eco-friendly products due to their recyclability, abundant availability and property variability. One key aspect of this sustainability effort is the development of eco-friendly materials, particularly bio composites derived from agricultural waste residues. The physical, mechanical and thermal properties as well as suitability of these fibers depend greatly on the methods used for extraction, processing, chemical modification and physical treatments. Understanding these processes comprehensively is essential for obtaining desired natural fibers/fillers from agricultural waste for creating effective bio composites to meet specific application demands. This study aims to provide a comprehensive assessment of the various extraction and modification techniques employed for natural fibers. It offers an in-depth review of diverse extraction processes, ranging from the initial harvesting to the decortication stage. It has been revealed that the choice of extraction methodologies depends on climate, water resources, local traditions, and the desired fiber quality. Additionally, the paper explores chemical and physical treatments, highlighting how each method influences the structure and properties of natural fibers. Overall, this review offers practical insights into the steps taken to transform agro-waste biomass into desired natural fiber and in turn biocomposite material, while enhancing product quality and performance. Biocomposite ; Environmentally friendly ; Sustainability ; Natural fiber ; Extraction (chemistry) ; Environmental science ; Fiber ; Materials science ; Biochemical engineering ; Natural resource ; Process engineering ; Composite material ; Engineering ; Composite number Natural Fiber Reinforced Composites ; Agricultural Engineering and Mechanization
Authors: Brian Musikavanhu | Yongdi Liang | Zhaoli Xue | Lei Feng | Long Zhao
Source: Molecules (review, 2023-10-06)
Field: Chemistry — Spectroscopy

Strategies for Improving Selectivity and Sensitivity of Schiff Base Fluorescent Chemosensors for Toxic and Heavy Metals Toxic cations, including heavy metals, pose significant environmental and health risks, necessitating the development of reliable detection methods. This review investigates the techniques and approaches used to strengthen the sensitivity and selectivity of Schiff base fluorescent chemosensors designed specifically to detect toxic and heavy metal cations. The paper explores a range of strategies, including functional group variations, structural modifications, and the integration of nanomaterials or auxiliary receptors, to amplify the efficiency of these chemosensors. By improving selectivity towards targeted cations and achieving heightened sensitivity and detection limits, consequently, these strategies contribute to the advancement of accurate and efficient detection methods while increasing the range of end-use applications. The findings discussed in this review offer valuable insights into the potential of leveraging Schiff base fluorescent chemosensors for the accurate and reliable detection and monitoring of heavy metal cations in various fields, including environmental monitoring, biomedical research, and industrial safety. Fluorescence ; Schiff base ; Selectivity ; Heavy metals ; Nanomaterials ; Nanotechnology ; Chemistry ; Combinatorial chemistry ; Biochemical engineering ; Environmental chemistry ; Materials science ; Organic chemistry ; Catalysis ; Stereochemistry Molecular Sensors and Ion Detection ; Advanced biosensing and bioanalysis techniques ; Electrochemical Analysis and Applications
Authors: Priscila Cavassin | Isabelle Holzer | Δήμητρα Τσόκκου | Olivier Bardagot | Julien Réhault | Natalie Banerji
Source: Advanced Materials (article, 2023-04-22)
Field: Materials Science — Polymers and Plastics

Electrochemical Doping in Ordered and Disordered Domains of Organic Mixed Ionic–Electronic Conductors Conjugated polymers are increasingly used as organic mixed ionic-electronic conductors in electrochemical applications for neuromorphic computing, bioelectronics, and energy harvesting. The design of efficient electrochemical devices relies on large modulations of the polymer conductivity, fast doping/dedoping kinetics, and high ionic uptake. In this work, structure-property relations are established and control of these parameters by the co-existence of order and disorder in the phase morphology is demonstrated. Using in situ time-resolved spectroelectrochemistry, resonant Raman, and terahertz (THz) conductivity measurements, the electrochemical doping in the different morphological domains of poly(3-hexylthiophene) (P3HT) is investigated. The main finding is that bipolarons are found preferentially in disordered polymer regions, where they are formed faster and are thermodynamically more favored. On the other hand, polarons show a preference for ordered domains, leading to drastically different bipolaron/polaron ratios and doping/dedoping dynamics in the distinct regions. A significant enhancement of the electronic conductivity is evident when bipolarons start forming in the disordered regions, while the presence of bipolarons in the ordered regions is detrimental for transport. This study provides significant advances in the understanding of the impact of morphology on the electrochemical doping of conjugated polymers and the induced increase in conductivity. Polaron ; Bipolaron ; Materials science ; Conductive polymer ; Doping ; Chemical physics ; Conductivity ; Ionic bonding ; Raman spectroscopy ; Electrochemistry ; Bioelectronics ; Ionic conductivity ; Polyacetylene ; Polymer ; Nanotechnology ; Electrode ; Ion ; Physical chemistry ; Optoelectronics ; Electrolyte ; Organic chemistry ; Chemistry ; Composite material ; Physics Conducting polymers and applications ; Organic Electronics and Photovoltaics ; Advanced Memory and Neural Computing
Authors: Lu Wang | Wenjuan Xue | Hejin Zhu | Xiangyu Guo | Hongliang Huang | Chongli Zhong
Source: Angewandte Chemie International Edition (article, 2023-01-04)
Field: Chemistry — Inorganic Chemistry

Stepwise Engineering the Pore Aperture of a Cage‐like MOF for the Efficient Separation of Isomeric C4 Paraffins under Humid Conditions The separation of isomeric C4 paraffins is an important task in the petrochemical industry, while current adsorbents undergo a trade-off relationship between selectivity and adsorption capacity. In this work, the pore aperture of a cage-like Zn-bzc (bzc=pyrazole-4-carboxylic acid) is tuned by the stepwise installation methyl groups on its narrow aperture to achieve both molecular-sieving separation and high n-C<sub>4</sub> H<sub>10</sub> uptake. Notably, the resulting Zn-bzc-2CH<sub>3</sub> (bzc-2CH<sub>3</sub> =3,5-dimethylpyrazole-4-carboxylic acid) can sensitively capture n-C<sub>4</sub> H<sub>10</sub> and exclude iso-C<sub>4</sub> H<sub>10</sub> , affording molecular-sieving for n-C<sub>4</sub> H<sub>10</sub> /iso-C<sub>4</sub> H<sub>10</sub> separation and high n-C<sub>4</sub> H<sub>10</sub> adsorption capacity (54.3 cm<sup>3</sup> g<sup>-1</sup> ). Breakthrough tests prove n-C<sub>4</sub> H<sub>10</sub> /iso-C<sub>4</sub> H<sub>10</sub> can be efficiently separated and high-purity iso-C<sub>4</sub> H<sub>10</sub> (99.99 %) can be collected. Importantly, the hydrophobic microenvironment created by the introduced methyl groups greatly improves the stability of Zn-bzc and significantly eliminates the negative effect of water vapor on gas separation under humid conditions, indicating Zn-bzc-2CH<sub>3</sub> is a new benchmark adsorbent for n-C<sub>4</sub> H<sub>10</sub> /iso-C<sub>4</sub> H<sub>10</sub> separation. Adsorption ; Chemistry ; Aperture (computer memory) ; Chromatography ; Chemical engineering ; Organic chemistry ; Engineering ; Mechanical engineering Metal-Organic Frameworks: Synthesis and Applications ; Covalent Organic Framework Applications ; Gas Sensing Nanomaterials and Sensors
Authors: Khaled Laadjal | António J. Marques Cardoso
Source: Electronics (article, 2023-03-08)
Field: Materials Science — Materials Chemistry

Multilayer Ceramic Capacitors: An Overview of Failure Mechanisms, Perspectives, and Challenges Along with the growing of population and social and technological improvements, the use of energy and natural resources has risen over the past few decades. The sustainability of using coal, oil, and natural gas as the main energy sources faces, however, substantial obstacles. Fuel cells, batteries, and super-capacitors have the highest energy densities, but due to their high-power density and rapid charge-discharge speed, regular dielectric capacitors are becoming more popular for pulsed power applications. High electric breakdown strength and high maximum but low-remnant (zero in the case of linear dielectrics) polarization are necessary for high energy density in dielectric capacitors. The high performance, multi-functionality, and high integration of electronic devices are made possible in large part by the multilayer ceramic capacitors (MLCCs). Due to their low cost, compact size, wide capacitance range, low ESL and ESR, and excellent frequency response, MLCCs play a significant role in contemporary electronic devices. From the standpoint of the underlying theories of energy storage in dielectrics, this paper emphasizes the significant problems and recent advancements in building extremely volumetric-efficient MLCCs. Following a thorough examination of the state-of-the-art, important parameters that may be used to improve energy-storage qualities are highlighted, such as controlling local structure, phase assembly, dielectric layer thickness, microstructure, conductivity, different failure modes, and the specific performance during the failure mechanism. The summary of some conclusions on the impending need for innovative materials and diagnostic methods in high-power/energy density capacitor applications appears at the end of the paper. Capacitor ; Ceramic capacitor ; Dielectric ; Materials science ; Film capacitor ; Engineering physics ; Capacitance ; Electrical engineering ; Power density ; Energy storage ; Optoelectronics ; Power (physics) ; Electronic engineering ; Voltage ; Engineering ; Physics ; Electrode Ferroelectric and Piezoelectric Materials ; Semiconductor materials and devices ; Dielectric materials and actuators
Authors: P. K. Miniappan | Sivagnanam Marimuthu | S. Dharani Kumar | Gopal Gokilakrishnan | Shubham Sharma | Changhe Li | Shashi Prakash Dwivedi | Mohamed Abbas
Source: REVIEWS ON ADVANCED MATERIALS SCIENCE (article, 2023-01-01)
Field: Materials Science — Polymers and Plastics

Mechanical, fracture-deformation, and tribology behavior of fillers-reinforced sisal fiber composites for lightweight automotive applications Abstract The main focus of this study is on the effects of fly ash, basalt powder, and tungsten carbide (WC) on the mechanical (tensile strength, flexural strength, impact strength, and Shore D hardness) and tribology behavior of sisal fiber-reinforced composites. Using epoxy resin, the fillers (5–10 wt% of each) were mixed with sisal fiber and resin (30 wt%). A tensile strength of 86.3–112.2 MPa was observed with the addition of fly ash, basalt powder, and WC fillers. The tensile strength of S2 composite (basalt powder + epoxy resin) was 33.63% higher than that of composite without fillers. The flexural strength of S5 composite (basalt powder + WC) was found to be 166.4 MPa, which is nearly 19.95% higher than the composite without filler. The fly ash with WC (S4) and basalt powder (S5) composite showed similar impact strength (5.34 J·m −2 ), which was nearly 62% greater than the composites without filler. The superior hardness was noticed in S5 composite compared to all other filler-added composites. The least wear rate was noticed in S3 (WC) composites irrespective of all the loading conditions. The hybridization of fillers also enhanced the mechanical properties of sisal fiber–reinforced composites. However, single filler–reinforced composite (WC) improved the wear resistance compare to hybrid filler–reinforced composites. The inclusion of filler increases the load-carrying capability and adhesion, as determined by scanning electron microscope. The river-like pattern confirms that S2-composite failure was dominated by ductile. The least wear debris and grooved surfaces were results higher wear resistance in the hybrid filler–reinforced composites. Materials science ; Composite material ; Ultimate tensile strength ; Flexural strength ; Composite number ; Filler (materials) ; Basalt fiber ; Epoxy ; SISAL ; Izod impact strength test ; Tribology ; Fiber Natural Fiber Reinforced Composites ; Tribology and Wear Analysis ; Brake Systems and Friction Analysis