An investigation into changes in lung function and the subjective medical benefits from breast reduction surgery. 
The aim of this study was to assess the respiratory changes following reduction mammaplasty in women presenting for elective surgery; In addition, to assess whether these changes might be related to any symptomatic improvement.  This was a prospective study examining women attending for breast reduction surgery over a 3-month period.  Preoperative pulmonary function studies (PFTs) and a symptom questionnaire were completed before operation.  These were repeated 6-8 weeks after surgery.  Pulmonary function testing was carried out in all cases by the same operator.  The study was carried out within a sub regional centre for plastic and reconstructive surgery.  Local Ethics committee approval was obtained.  Nineteen healthy women mean age 34.9 years and with a mean Body Mass Index of 27.62 were recruited.  The mean weight of excised breast tissue was 1546 g. All preoperative pulmonary function tests were within normal limits.  Six of the women smoked, none changed their smoking habits over the course of this study.  Changes in pulmonary function studies were analysed using the paired t-test.  A 'P' value of < 0.05 was considered to be significant.  Seventeen women had a post operative improvement in PFTs.  Statistically significant improvements were obtained for changes in peak expiratory flow rate (PEFR, P = 0.005) and peak inspiratory flow rate (PIFR, P < 0.0001).  The 'P' values for changes in FEV1 (forced expired volume in 1 second) and FEV1/FVC (forced vital capacity) did not reach significance, whilst the 'P' value for the change in FVC was statistically significant (P = 0.01), although the actual mean change was small (0.07 litres).  The study sample was too small to relate these changes to mass of excised tissue or BMI.  All women taking part claimed an increased confidence and a cessation in analgesic use.  Other reported benefits included an improved exercise tolerance (12/19), reduced sleep disturbance (4/19) and reduced breathing difficulties (1/19).