[Effect of HSP70 gene polymorphism on genetic susceptibility of pneumoconiosis of coal worker]. 
To explore the effect of heat shock protein 70(HSP70) gene polymorphism on genetic susceptibility of pneumoconiosis of coal worker (CWP).  100 workers whose sternites were assessed 0+ were chosen as the case group and 100 workers as the control.  HSP70 genotypes were analyzed by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique.  There were significantly differences in HSP70-1 b2/b2 genotype (chi2 = 8.26, P < 0.05) between the case group and the control ,the risks of CWP in the individuals with b2/b2 genotype were 2.36 times than those with b1/b1 genotype.  The polymorphism of HSP70-2 and HSP70-hom had no statistics significance in the difference of the two groups.  The results suggested that the individual with HSP70-1 b2/b2 genotype may be a predisposing genotype to CWP and the individuals with the genotype could have weaker adaptability than the others.