Electroacupuncture treatment of morphine-dependent mice reduces signs of withdrawal, without showing cross-tolerance. 
Morphine pellets (75 mg morphine base per pellet) were implanted subcutaneously in mice (B6AF1/J) and were surgically removed after 3 or 8 days.  During morphine abstinence (7 h after pellet removal), the mice were treated with electroacupuncture (EA).  The results indicate that EA analgesia shows no cross-tolerance to morphine.  Additionally, EA reduced withdrawal behaviour (jumping) in 50% of the mice during morphine abstinence.