Compound: chlorothiazide
SMILES: NS(=O)(=O)c2cc1c(N=CNS1(=O)=O)cc2Cl 
Molecular weight: 295.72900000000004
Number of H-bond donors: 2
Number of rings: 2
Number of rotatable bonds: 1
Polar surface area: 118.69
Minimum degree: 1
ESOL predicted log solubility (mol/L): -1.7519999999999998
Measured log solubility (mol/L): -3.05