import warnings class TargetNotDNAError(Exception): def __init__(self, message="The target sequence must be DNA."): self.message = message super().__init__(self.message) class DonorNotDNAError(Exception): def __init__(self, message="The donor sequence must be DNA."): self.message = message super().__init__(self.message) class TargetLengthError(Exception): def __init__(self, message="The target sequence must be exactly 14 nucleotides long."): self.message = message super().__init__(self.message) class DonorLengthError(Exception): def __init__(self, message="The donor sequence must be exactly 14 nucleotides long."): self.message = message super().__init__(self.message) class CoreMismatchError(Exception): def __init__(self, message="That target and donor cores must be the same."): self.message = message super().__init__(self.message) def DonorP7CWarning(): warnings.warn("Donor P7 is C, this was found to be very inefficient in a screen.") def MatchingP6P7Warning(): warnings.warn("Target P6-P7 and Donor P6-P7 match, efficiency is unclear. DBL HSG forced to be anti-complementary.") def NotCTorGTCoreWarning(): warnings.warn("Core is not CT or GT, efficiency is unclear.") def NotNTCoreWarning(): warnings.warn("Core does not follow the expected NT format, likely inefficient.")