Jabarkan Jalur métabolis dari Énzim dalam bahasa sunda

Sababaraha énzim bisa gawé bareng ngawangun hiji susunan husus, nyiptakeun jalur métabolis. Dina hiji jalur métabolis, hiji énzim nyokot produk énzim séjén salaku substrat. Satutasna réaksi katalitis, produkna dibikeun ka énzim séjénna. Produk ahir jalur sarupa kitu kadang jadi inhibitor pikeun salah sahiji énzim-énzim na awal jalur (biasana léngkah kahiji nu teu bisa balik, disebut committed step), sahingga ngatur jumlah produk ahir nu dijieun ku jalur éta.

Gambar 6: Mékanisme inhibisi eupan-balik nu ilahar.

The basic feedback inhibition mechanism, where the product (P) inhibits the committed step (A->B).

Sequential feedback inhibition. The end products P1 and P2 inhibit the first committed step of their individual pathway (C->D or C->F). If both products are present in abundance, all pathways fron C are blocked. This léads to a buildup of C, which in turn inhibits the first common committed step A->B.

Enzyme multiplicity. éach end product inhibits both the first individual committed step and one of the enzymes performing the first common committed step.

Concerted feedback inhibition. éach end product inhibits the first individual committed step. Together, they inhibit the first common committed step.

Cumulative feedback inhibition. éach end product inhibits the first individual committed step. Also, éach end product partially inhibits the first common committed step.