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Blake Lively as Serena van der Woodsen

Leighton Meester as Blair Waldorf

Penn Badgley as Daniel "Dan" Humphrey

Chace Crawford as Nathaniel "Nate" Archibald

Taylor Momsen as Jennifer "Jenny" Humphrey

Ed Westwick as Charles "Chuck" Bass

Kelly Rutherford as Lilian 'Lily' van der Woodsen (née Rhodes)

Matthew Settle as Rufus Humphrey

Jessica Szohr as Vanessa Abrams

Kaylee DeFer as Ivy Dickens

Connor Paolo as Eric van der Woodsen

Margaret Colin and Wallace Shawn as Eleanor Waldorf and Cyrus Rose

Michelle Trachtenberg and Sebastian Stan as Georgina Sparks and Carter Baizen

Robert John Burke as Bartholomew Bass

Amanda Setton, Nicole Fiscella, Nan Zhang, Dreama Walker and Yin Chang as Penelope Shafai, Isabel Coates, Kati Farkas, Hazel Williams and Nelly Yuki