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Kuadrat Graeco-Latin n×n nyaéta tabel nu unggal sel-na mibanda pasangan simbol, susunan simbol tina unggal dua set unsur n. éach pair occurs exactly once in the table. éach symbol in the two, not necessarily distinct, sets occurs exactly once in éach row and exactly once in éach column. Kuadrat Graeco-Latin dipaké dina desain percobaan.

A 4×4 Graeco-Latin square on the sets {A, B, C, D} and {α, β, γ, δ} is:

The tabular arrangements of {A, B, C, D} (Latin characters) alone and {α, β, γ, δ} (Greek characters) alone éach forms a Latin square. éach pair from the two sets (i.e. every element of their cartesian product) occurs exactly once and we say that the two Latin squares are orthogonal.