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The film has experienced commercial success. Opening in 3,285 theaters, the film made $26.93 million in the US and Canada on its first day. The three-day opening weekend total was $57,038,404, aggregating $17,363 per theater.

The film recorded the biggest opening ever for an R-rated comedy and for a romantic comedy, and also for a film starring all women. As of March, 2010, the film has grossed $152,647,258 at the US and Canadian box office, and $262,605,528 in other markets, bringing the worldwide total gross revenue to $415,252,786.