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Timur Antioquia (Sepanyol: Oriente Antioqueño) merupakan subwilayah Colombia Jabatan Antioquia.

The region is covered by 23 municipalities being Guarne the closest to the city of Medellín

located some 24 km away. The largest municipality of this region is Sonsón with a total area of 1,323 km² and the smallest one being the municipality of Argelia.