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Dalam novel fiksyen sains Methuselah's Children, karya Robert A. Heinlein,  Heinlein described a future race of super-intelligent humans yang menggunakan sistem angka asas-60, as well as an alphabet of exactly sixty ideographs.

In Stel Pavlou's novel Decipher, this nombor system is the center of focus, as the buckyball carbon element is used in the book to store data, dan only base 60 is found to be able to be successfully understood by the computers used in it. At least one popular book uses the spelling "sexigesimal" instead of "sexagesimal," with the latter being the more common spelling of the word.

Book VIII of Plato's Republic involves an allegory of marriage centered on the nombor 604 = 12,960,000 dan its divisors. This nombor has the particularly simple sexagesimal representation 1:0:0:0:0. Later scholars have invoked both Babylonian mathematics dan music theory in an attempt to explain this passage.