Jabarkan smi23d –3D Coordinate Generation dari SMILES

Daylight Depict –Translate a SMILES formula into graphics

GIF/PNG-Creator for 2D Plots of Chemical Structures

JME molecule editor  - Chemical editor/viewer and SMILES/SMARTS generator in Java

JSME molecule editor  - Free chemical editor/viewer and SMILES/SMARTS generator in JavaScript

Marvin  by ChemAxon–online chemical editor/viewer and SMILES generator/converter

Instant JChem  by ChemAxon–desktop application for storing/generating/converting/visualizing/searching SMILES structures, particularly batch processing; personal edition free

JChem for Excel  by ChemAxon–MS Excel add-in for storing/generating/converting/visualizing/searching SMILES structures

Smormo-Ed–a molecule editor for Linux which can read and write SMILES

InChI.info–an unofficial InChI website featuring on-line converter from InChI and SMILES to molecular drawings

Balloon–A free program for 3D coordinate generation and conformational analysis.

Indigo –an open-source cross-platform cheminformatics library with a plugin for IUPAC-compliant molecule and reaction 2D structural formula rendering.

Open Babel–an open-source chemical toolbox allowing anyone to search, convert, analyze, or store biochemical data.

Bioclipse–a free and open source workbench for the life sciences

MolEngine –A .NET cheminformatics toolkit to read/write SMILES, generate 2D coordinate from SMILES, and convert SMILES from/into other Chemical file formats.

JSDraw –A cross-platform javascript chemical structure editor to generate SMILES and SMARTS.