Gw mau tau Prestasi dari Isco

Tercera División Group VI: 2010–11

La Liga: 2016–17, 2019–20, 2021–22

Piala Super Spanyol: 2017, 2019–20, 2021–22

Liga Champions UEFA: 2013–14, 2015–16, 2016–17, 2017–18, 2021–22

Piala Super UEFA: 2014, 2016, 2017

Piala Dunia Antarklub FIFA: 2014, 2016, 2017, 2018

Piala Dunia U-17 FIFA tempat ketiga: 2009

Kejuaraan Eropa U-21 UEFA: 2013

La Liga Breakthrough Player: 2012

UEFA European Under-21 Championship Bronze Boot: 2013

UEFA European Under-21 Championship Team of the Tournament: 2013

UEFA Champions League Team of the Season: 2016–17

FIFA FIFPro World XI 2nd team: 2017

FIFA FIFPro World XI 3rd team: 2018

FIFA FIFPro World XI 5th team: 2013