Jabarkan Pemeran dari Scream 4

Film ini pertama kali diumumkan The Weinstein Company pada Juli 2008, dengan Wes Craven yang berkata dia tidak keberatan akan menyutradarainya jika skenarionya sebagus Scream. Pada Maret 2010, Craven mengkonfirmasikan bahwa dia akan menjadi sutradaranya  dan menyatakan bahwa "I am delighted to accept Bob Weinstein's offer to take the reins on a whole new chapter in 'Scream' history. Working with Courteney, David and Neve was a blast ten years ago and I'm sure it will be again. And I can't wait to find the talent that will bring new blood to the screen as well. Kevin is right on his game with the new script - the characters and story crackle with energy and originality - to say nothing of some of the most hair-raising scares I've seen in a script since... well, since the original 'Scream' series. Let me at it".