Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Input: Consider Input: Riociguat (Adempas(®)), a soluble guanylate cyclase stimulator, is a new, first-in-class drug approved for the treatment of patients with chronic thromboembolic pulmonary hypertension (CTEPH) [inoperable or persistent/recurrent following surgery] or pulmonary arterial hypertension (PAH). It has been designated an orphan medicine by the European Medicines Agency and the US FDA. This article reviews the available pharmacological properties of oral riociguat and its clinical efficacy and tolerability in adults with CTEPH or PAH. Riociguat is effective and well tolerated in patients with inoperable CTEPH or persistent/recurrent CTEPH following pulmonary endarterectomy, and in patients with PAH. It has a positive result on exercise capacity and pulmonary haemodynamics, and improves WHO functional class. Most adverse events can be attributed to the vasodilatory mechanism of riociguat; however, there is a potential for serious bleeding and fetal harm, and riociguat use is contraindicated in pregnant patients. Pulmonary endarterectomy remains the first treatment of choice for CTEPH, as it is potentially curative. Head-to-head trials comparing riociguat with the approved phosphodiesterase type 5 inhibitors in patients with PAH would be of value for the placement of riociguat in the management of this disease. Riociguat is a promising addition to the treatment options for patients with CTEPH or PAH.

Output: What is generic name of drug Adempas?


Input: Consider Input: What happens inside the skull of a soccer player who repeatedly heads a soccer ball? That question motivate a challenging new study of the brains of experienced players that has caused discussion and debate among soccer players, and some anxiety among those of us with soccer-playing children. For the study, researchers at the Albert Einstein College of Medicine in New York selected 34 adults,men and women. All of the volunteers had played soccer since childhood and now competed year-round in adult soccer leagues. Each filled out a detailed questionnaire developed especially for this study to determine how many times they had headed a soccer ball in the previous year, as well as whether they had experienced any known concussions in the past. Then the players completed computerized tests of their memory and other learning skills and had their brains scanned, using a complicated new MRI technique which can find structural changes in the brain that can't be seen during most scans. According to the data they presented at a Radiological Society of North America meeting last month,the researchers found that the players who had headed the ball more than about 1,100 times in the previous 12 months showed significant loss of white matter in parts of their brains involved with memory,attention and the processing of visual information, compared with players who had headed the ball fewer times. This pattern of white matter loss is "similar to those seen in traumatic brain injury" , like that after a serious concussion, the researchers reported,even though only one of these players was reported to have ever experienced a conc ussion. The players who had headed the ball about 1,100 times or more in the past year were also generally worse at recalling lists of words read to them, forgetting or _ the words far more often than players who had headed the ball less.

Output: What is likely to be the cause of memory loss?


Input: Consider Input: The Dolphins' eighth game was an AFC duel with the Ravens. The Dolphins trailed early after QB Joe Flacco completed a 32-yard TD pass to RB Willis McGahee. They replied with RB Ronnie Brown getting a 12-yard TD run. The Ravens got the lead back after kicker Billy Cundiff made a 26 and a 39-yard field goal. The Dolphins narrowed the lead with kicker Dan Carpenter nailing a 19-yard field goal. The Dolphins fell further behind after Flacco found WR Derrick Mason on a 12-yard TD pass. This was followed in the 4th quarter by Cundiff hitting a 20 and a 24-yard field goal.


Output: Who's touchdown pass was longer, Derrick Mason or Willis McGahee?