Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Are synthetic antifibrinolytics associated with an increased incidence of baffle fenestration closure after the modified Fontan procedure?
Answer: Use of epsilon-aminocaproic acid and tranexamic acid is not associated with early baffle fenestration closure after the modified Fontan procedure. It is concluded that these agents can be used without increasing the risk of spontaneous baffle fenestration closure.

Answer: no


Question: Question: Do combined effects of obesity and type 2 diabetes contribute to increased breast cancer risk in premenopausal women?
Answer: Obesity and type 2 diabetes, owing to their effects on adipocytokines and inflammatory mediators, contribute to increased breast cancer risk in premenopausal women. This study emphasizes healthy life style and better management of these metabolic disorders to avoid the pathogenesis of breast cancer and of other chronic diseases.

Answer: yes


Question: Question: Are thymidylate synthase and folyl-polyglutamate synthase clinically useful markers of response to pemetrexed in patients with malignant pleural mesothelioma?
Answer: Although previous retrospective data suggest that TS and FPGS expression might be potential markers of Pem efficacy in MPM, our data indicate these markers lack sufficient predictive value in individual patients and should not be used to guide therapeutic decisions in the absence of prospective studies.

Answer:
no