Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

[Q]: Question: Is 14-3-3η a novel mediator associated with the pathogenesis of rheumatoid arthritis and joint damage?
Answer: Extracellular 14-3-3η activates key signalling cascades and induces factors associated with the pathogenesis of RA at concentrations found in patients with RA, and its expression is higher in patients with radiographic damage and RA progression.
[A]: yes


[Q]: Question: Does presence of the full-length KIR2DS4 gene reduce the chance of rheumatoid arthritis patients to respond to methotrexate treatment?
Answer: Our results suggest that the response of RA patients with medium ESR values to MTX treatment may be dependent on the full-length KIR2DS4 gene.
[A]: yes


[Q]: Question: Does protease-mediated human smooth muscle cell proliferation by urokinase require epidermal growth factor receptor transactivation by triple membrane signaling?
Answer: In human coronary VSMC, uPA induces uPAR-independent, domain-dependent smooth muscle cell proliferation through transactivation of EGFR by a plasmin-mediated, ADAM-induced, and HB-EGF-dependent process, which is mediated by the intracellular pathways involving Gαi, Gβγ, src, and NAD(P)H oxidase.
[A]:
yes