Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does the ets-domain transcription factor Spdef promote maturation of goblet and paneth cells in the intestinal epithelium?
Answer: Spdef acts downstream of Math1 to promote terminal differentiation of a secretory progenitor pool into Paneth and goblet cells.
yes

Question: Does constitutive secretion of Interleukin-4 dictate CD133+ side population cells to resist drug treatment and cell death?
Answer: Our data suggest that the autocrine secretion of IL-4 is a potential target for the development of novel anticancer drugs to prevent the CSCs-mediated therapy failure and tumorigenesis.
yes

Question: Are failure of tooth eruption and brachydactyly in pseudohypoparathyroidism related to plasma parathyroid hormone-related protein levels?
Answer: We described the dental abnormalities in a large series of PHP patients that were followed in a single tertiary center. No relationship between plasma PTHrP levels and failure of tooth eruption, dental manifestations of PHP or brachydactyly was found. It is important that doctors pay attention to dental manifestations of the disease in order to refer patients to a proper care with dentists.

no