Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Example Input: Question: Does δNp63α enhance the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2?
Answer: Here, we report that GLI2 is the novel target gene of ΔNp63α and that ΔNp63α-GLI2 crosstalk in osteosarcoma cells is a necessary event in osteosarcoma progression. Defining the exact mechanisms involved in this interaction that mediate the pathogenesis of osteosarcoma promises to identify targets for drug therapy.
Example Output: yes

Example Input: Question: Does pharmacological preconditioning using intraportal infusion of L-arginine protect against hepatic ischemia reperfusion injury?
Answer: Pharmacological preconditioning with intraportal L-arginine provided protection against hepatic I/RI in early phases of the reperfusion period. The mechanisms underlying the protective effect may include preservation of the mitochondrial structure and inhibition of caspase-3 activity.
Example Output: yes

Example Input: Question: Does toll-like receptor 4 signaling contribute to Paclitaxel-induced peripheral neuropathy?
Answer: The toll-like receptor TLR4 and MyD88 signaling pathway could be a new potential therapeutic target in paclitaxel-induced painful neuropathy.
Example Output:
yes