In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Input: Consider Input: Question: Acetylation of histones affects transcription: 
 Options:  <1> Blocking the incorporation of other components of the transcription machinery. <2> Preventing the remodeling of chromatin. <3> Facilitating the action of helicases. <4> Decreasing sensitivity to nuclear receptors. <5> Reducing the affinity of histones for DNA.

Output: 5


Input: Consider Input: Question: It is characteristic of the alpha helix: 
 Options:  <1> Present 3.6 amino acid residues per turn. <2> Be levorotatory <3> Be stabilized by intrachain disulfide bridges. <4> Present ionic bonds between amino and ketone groups loaded with peptide bonds. <5> Have the side chains of the amino acids inwards.

Output: 1


Input: Consider Input: Question: When performing a central peripheral insertion venous catheterization procedure, the nurse must take into account that: 
 Options:  <1> The catheter is ready for use immediately after insertion, not needing further checks. <2> It is vital to perform a chest X-ray and / or an electrocardiographic record prior to its use. <3> A complete electrocardiogram should be performed in order to avoid possible complications. <4> The location of the tip of the catheter is only checked if parenteral nutrition is to be administered through it. <5> You need to check your position using a chest x-ray and another abdomen.


Output: 2