Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

[Q]: Question: Does protamine affect the formation of cGMP or cAMP in pig vascular smooth muscle cells in response to vasodilators?
Answer: These experiments show that protamine does not alter the responses of the intracellular second messengers, cGMP and cAMP, to the vasodilators sodium nitroprusside, atrial natriuretic peptide, isoproterenol, and forskolin. These results do not support the hypothesis that protamine sensitizes vascular smooth muscle cells to the endothelium-derived relaxing factor, nitric oxide.
[A]: no


[Q]: Question: Does indoleamine 2,3-dioxygenase inhibition alter the non-coding RNA transcriptome following renal ischemia-reperfusion injury?
Answer: These results suggest a biologic role for non-coding, IDO-dependent genes in regulating the early response to IRI.
[A]: yes


[Q]: Question: Does potential prognostic marker ubiquitin carboxyl-terminal hydrolase-L1 predict patient survival in non-small cell lung carcinoma?
Answer: Although UCH-L1 appears to be involved in carcinogenic processes in NSCLC cell lines, the absence of correlation with patient survival indicates that caution is required in the use of UCH-L1 as a potential prognostic marker for advanced stage and metastasis in lung carcinoma.
[A]:
no