In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Ex Input:
Question: What kind of validity does the degree of confidence refer to, with which it can be inferred that the cause-effect relationships between the variables of an investigation are interpretable in the sense suggested by the researcher? 
 Options:  <1> Internal validity <2> External validity <3> Discriminant validity <4> Ecological validity <5> Construct validity

Ex Output:
1


Ex Input:
Question: Indicate the amino acid that, under physiological conditions, has an uncharged side chain: 
 Options:  <1> Arginine <2> Aspartic acid. <3> Glutamic acid. <4> Lysine <5> Threonine

Ex Output:
5


Ex Input:
Question: In a pharmacoeconomic study, drug A produces a life expectancy of 5 years with a total cost of 5,000 euros, while drug B produces a life expectancy of 6 years with a total cost of 15,000 euros (average values ​​per patient) . The decision criterion is based on choosing the most effective intervention with a cost-effectiveness threshold of 30,000 euros per year of additional life earned per patient, what drug is cost-effective compared to the other and why? 
 Options:  <1> Drug B, because the incremental cost-effectiveness with respect to A is below the cost-effectiveness threshold. <2> Drug A, because it costs much less than B and there is only one year of difference in life expectancy. <3> Drug A, because the incremental cost-effectiveness of B with respect to A is above the cost-effectiveness threshold. <4> Drug B, because each year of life has a cost of 29,500 euros below the cost-effectiveness threshold. <5> Drug A, because the incremental cost-effectiveness with respect to B is above the cost-effectiveness threshold.

Ex Output:

1