In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

Q: Human bocavirus (HBoV) was recently discovered in children with respiratory distress and/or diarrhea. To our knowledge, no previous study has reported the existence of bocavirus in Saudi Arabia. Swabs samples from 80 children with respiratory tract infections were examined for the presence of HBoV. Real-time polymerase chain reaction was used as a sensitive method to detect the HBoV. Direct gene sequencing was used to determine the genotype of the detected virus isolates. HBoV was detected in 22.5% of the examined patients. The NP1 partial gene sequence from all patients showed that the circulated strains were related to HBoV-1 genotype. Most of HBoV infected patients showed evidence of mixed coinfection with other viral pathogens. The current study clearly demonstrated that genetically conserved HBoV1 circulates in Saudi Arabia. Interestingly, most of the HBoV1 infected cases were associated with high rates of co-infections with other viruses.

A: Detection of Bocavirus in Children Suffering from Acute Respiratory Tract Infections in Saudi Arabia
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Q: Genome Detective is a web-based, user-friendly software application to quickly and accurately assemble all known virus genomes from next generation sequencing datasets. This application allows the identification of phylogenetic clusters and genotypes from assembled genomes in FASTA format. Since its release in 2019, we have produced a number of typing tools for emergent viruses that have caused large outbreaks, such as Zika and Yellow Fever Virus in Brazil. Here, we present The Genome Detective Coronavirus Typing Tool that can accurately identify the novel severe acute respiratory syndrome (SARS) related coronavirus (SARS-CoV-2) sequences isolated in China and around the world. The tool can accept up to 2,000 sequences per submission and the analysis of a new whole genome sequence will take approximately one minute. The tool has been tested and validated with hundreds of whole genomes from ten coronavirus species, and correctly classified all of the SARS-related coronavirus (SARSr-CoV) and all of the available public data for SARS-CoV-2. The tool also allows tracking of new viral mutations as the outbreak expands globally, which may help to accelerate the development of novel diagnostics, drugs and vaccines to stop the COVID-19 disease.

A: Genome Detective Coronavirus Typing Tool for rapid identification and characterization of novel coronavirus genomes
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Q: R. and PEYMANN 3. 1994. Diagnosis of &&sia caba& infections in horses by enzymelinked immunosorbent assay (ELBA) and Western blot. inrernntionalJaurnulfnr Parasitology 24: 341-346. From Bubesia cabal/i in vitro cultures a preparation of 100% infected erythrocytes was obtained. From this, B. cabutli antigens were extracted with the detergent 3-[(3-CholamidopropyI)-dimethylammonio]-lpropane-sulfonate (CHAPS) and used as ELISA antigens. A control antigen of normal erythrocytes from the same donor horse was prepared in an identical manner. The ELBA and Western blot were validated by testing of sera from horses experimentally infected with B. caballi or B. equi or not infected with Babesia spp. ELISA and Western blot results were compared with those obtained by the immunofluorescence antibody test (IFAT) and complement fixation test (CFT). The sensitivity of the ELISA of98.3% obtained for sera from day 14 after infection was superior to the Western blot (94.9%), the IFAT (96.6%) and the CFT (28.8%). No positive results were obtained in the ELISA and Western blot with 106 sera from horses not infected with &b&a spp. resulting in a calculated specificity of 100% for both tests. Cross reactions of 8. cqui-positive sera did occur to a larger extent in the ELBA (20%) than in the IFAT (4%). No cross reactions were observed with the Western blot and the CFT. The higher sensitivity of the ELISA was also demonstrated by testing of t 32 field sera: more positi~s resuhs were obtained by ELBA (112) as compared to IFAT (92) or CFT (41). The validity of these results was confirmed by testing of sera by Western blot. The ELBA as the most sensitive test provides the best method for the identifi~tion of carrier horses to prevent the introduction into non-endemic areas (export testing). Positive ELBA results can be confirmed by Western blot, if a species-specific diagnosis is required. 20: 4348.

A:
DIAGNOSIS OF BABESIA CABALLI INFECTIONS IN HORSES BY ENZYME-LINKED IMMUNOSORBENT ASSAY (ELISA) AND WESTERN BLOT
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