TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Does maraviroc concentrate in the cervicovaginal fluid and vaginal tissue of HIV-negative women?
Answer: Higher maraviroc exposure in the female genital tract provides a pharmacologic basis for further evaluation of chemokine receptor 5 antagonists in HIV infection prophylaxis. This is the first study to report antiretroviral VT concentrations, CVF protein binding, and CVF terminal elimination.

SOLUTION: yes

PROBLEM: Question: Does mechanical ventilation with lower tidal volumes influence the prescription of opioids or sedatives?
Answer: Concerns regarding sedation requirements with use of lower V(T) are unfounded and should not preclude its use in patients with ALI/ARDS.

SOLUTION: no

PROBLEM: Question: Do altered intracellular sorting signals influence the efficacy of genetic melanoma vaccines incorporating helper determinants in mice?
Answer: Altered intracellular sorting signals do not significantly influence the efficacy of genetic melanoma vaccines incorporating helper determinants in our model system. These results further support the concept that linkage of immunogenic helper sequences can be successfully applied for antigen-specific immunotherapy of melanoma and provide a scientific basis for the translation of this strategy in future clinical applications.

SOLUTION:
no