TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Does apelin-13 protect the heart against ischemia-reperfusion injury through the RISK-GSK-3β-mPTP pathway?
Answer: The protective mechanism of apelin-13 might be that inactivation of GSK-3β could inhibit the opening of mPTP by activating PI3K/Akt and ERK1/2 involved in the reperfusion injury salvage kinase (RISK) pathway.

SOLUTION: yes

PROBLEM: Question: Do norepinephrine and ephedrine counteract the increase in cutaneous microcirculation induced by spinal anaesthesia?
Answer: Improved skin perfusion induced by spinal anaesthesia was not counteracted by the use of norepinephrine or ephedrine.

SOLUTION: no

PROBLEM: Question: Does chronic binge alcohol consumption diminish effectiveness of continuous antiretroviral suppression of viral load in simian immunodeficiency virus-infected macaques?
Answer: These findings indicate that CBA does not attenuate effectiveness of NRTI suppression of viral load, nor does it appear to interact with NRTI to produce toxicity during the initial 2 months of treatment. We conclude that while efforts to reduce AUD in PLWHA should be a priority, counseling on the importance of adherence to ART even on drinking days should also be promoted.

SOLUTION:
no