In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

[Q]: Paragraph: Retroviruses are classified as exogenous and endogenous retroviruses according to the mode of transmission. Endogenous retroviruses (ERVs) are retroviruses which have been integrated into germ-line cells and inherited from parents to offspring. Most ERVs are inactivated by deletions and mutations; however, certain ERVs maintain their infectivity and infect the same host and new hosts as exogenous retroviruses. All domestic cats have infectious ERVs, termed RD-114 virus. Several canine and feline attenuated vaccines are manufactured using RD-114 virus-producing cell lines such as Crandell-Rees feline kidney cells; therefore, it is possible that infectious RD-114 virus contaminates live attenuated vaccines. Recently, Japanese and UK research groups found that several feline and canine vaccines were indeed contaminated with infectious RD-114 virus. This was the first incidence of contamination of 'infectious' ERVs in live attenuated vaccines. RD-114 virus replicates efficiently in canine cell lines and primary cells. Therefore, it is possible that RD-114 virus infects dogs following inoculation with contaminated vaccines and induces proliferative diseases and immune suppression, if it adapts to grow efficiently in dogs. In this review, we summarize the incidence of contamination of RD-114 virus in live attenuated vaccines and potential risks of infection with RD-114 virus in dogs. Retroviruses enter host cells via binding of the envelope proteins with the host receptor(s). After entering the cells, viral RNA is reverse-transcribed into DNA and then the DNA is integrated into the host genome to be a provirus. Viral RNA is transcribed from the provirus and the structural and enzymatic proteins of the virus are synthesized from the transcribed viral RNA. Retroviruses are classified as exogenous and endogenous retroviruses according to the mode of transmission [14] . Usually, exogenous retroviruses infect somatic cells but not germ-line cells, and they are transmitted horizontally by infection via viral particles. On the other hand, ERVs are retroviruses which have been integrated into germ-line cells. ERVs behave like normal genes and are inherited from parents to offspring as Mendelian's law. ERVs occupy about 10 % of mammalian genomes and are mostly inactivated by deletions and mutations [14, 15, 17, 27] . However, a limited number of ERVs maintain their infectivity and infect new hosts as exogenous retroviruses [6] . Exogenous retroviruses are classified into seven genera, i.e., alpharetrovirus, betaretrovirus, gammaretrovirus, deltaretrovirus, epsilonretrovirus, spumaretrovirus and Electronic supplementary material The online version of this article ( 
 Title: Contamination of live attenuated vaccines with an infectious feline endogenous retrovirus (RD-114 virus)
[A]: True


[Q]: Paragraph: The recent Ebola virus disease outbreak emphasized the potential misuse of personal protective equipment (PPE) by health care workers (HCWs) during such an event. We aimed to compare selfperceived proficiency of PPE use and objective performance, and identify predictors of low compliance and PPE misuse. Methods: An observational study combined with subjective questionnaires were carried out during a bioterror simulation drill. Forty-two observers evaluated performance under PPE. Mistakes were recorded and graded using a structured observational format and were correlated with the subjective questionnaires and with demographic parameters. Results: One hundred seventy-eight HCWs from community clinics and hospitals were included. The mean self-perceived proficiency was high (6.1 out of 7), mean level of comfort was moderate (4.0 out of 7), and mean objective performance was intermediate (9.5 out of 13). There was no correlation between comfort and objective performance scores. Self-perceived proficiency was in correlation with donning and continuous performance with PPE but not with doffing. Clinic personnel performed better than personnel in hospitals (40.3% vs 67.8% with 3 or more mistakes, respectively; P = .001). Demographic characteristics had no correlation with objective or self-perceived performance. Conclusions: Self-perceived proficiency is a poor predictor of appropriate PPE use. The results suggest poor awareness of the possibility of PPE misuse. 
 Title: The association between self-perceived proficiency of personal protective equipment and objective performance: An observational study during a bioterrorism simulation drill
[A]: False


[Q]: Paragraph: The respiratory syndrome caused by a new type of coronavirus has been emerging from 2 China and caused more than 1000 death globally since December 2019. This new virus, 3 called 2019 novel coronavirus (2019-nCoV) uses the same receptor called Angiotensin-4 converting enzyme 2 (ACE2) to attack humans as the coronavirus that caused the severe 5 acute respiratory syndrome (SARS) seventeen years ago. Both viruses recognize ACE2 6 through the spike proteins (S-protein) on their surfaces. It was found that the S-protein 7 from the SARS coronavirus (SARS-CoV) bind stronger to ACE2 than 2019-nCoV. 8 However, function of a bio-system is often under kinetic, rather than thermodynamic, 9 control. To address this issue, we constructed a structural model for complex formed 10 between ACE2 and the S-protein from 2019-nCoV, so that the rate of their association 11 can be estimated and compared with the binding of S-protein from SARS-CoV by a 12 multiscale simulation method. Our simulation results suggest that the association of new 13 virus to the receptor is slower than SARS, which is consistent with the experimental data 14 obtained very recently. We further integrated this difference of association rate between 15 virus and receptor into a mathematical model which describes the life cycle of virus in 16 host cells and its interplay with the innate immune system. Interestingly, we found that 17 the slower association between virus and receptor can result in longer incubation period, 18 while still maintaining a relatively higher level of viral concentration in human body. Our 19 computational study therefore provides, from the molecular level, one possible 20 explanation that the new disease by far spread much faster than SARS. 21 22 23 24 25 26 27 author/funder. All rights reserved. No reuse allowed without permission. 
 Title: A Multiscale and Comparative Model for Receptor Binding of 2019 Novel Coronavirus and the Implication of its Life Cycle in Host Cells
[A]:
True