instruction:
This task is about writing a correct answer for the reading comprehension task. Based on the information provided in a given passage, you should identify the shortest continuous text span from the passage that serves as an answer to the given question. Avoid answers that are incorrect or provides incomplete justification for the question.
question:
Passage: Antibiotics are screened for any negative effects on humans or other mammals before approval for clinical use, and are usually considered safe and most are well tolerated. However, some antibiotics have been associated with a range of adverse side effects. Side-effects range from mild to very serious depending on the antibiotics used, the microbial organisms targeted, and the individual patient. Side effects may reflect the pharmacological or toxicological properties of the antibiotic or may involve hypersensitivity reactions or anaphylaxis. Safety profiles of newer drugs are often not as well established as for those that have a long history of use. Adverse effects range from fever and nausea to major allergic reactions, including photodermatitis and anaphylaxis. Common side-effects include diarrhea, resulting from disruption of the species composition in the intestinal flora, resulting, for example, in overgrowth of pathogenic bacteria, such as Clostridium difficile. Antibacterials can also affect the vaginal flora, and may lead to overgrowth of yeast species of the genus Candida in the vulvo-vaginal area. Additional side-effects can result from interaction with other drugs, such as elevated risk of tendon damage from administration of a quinolone antibiotic with a systemic corticosteroid. Some scientists have hypothesized that the indiscriminate use of antibiotics alter the host microbiota and this has been associated with chronic disease. Question: What is one possible serious side effect of over-using antibiotics?
answer:
alter the host microbiota


question:
Passage: The Tibetan Empire emerged in the 7th century, but with the fall of the empire the region soon divided into a variety of territories. The bulk of western and central Tibet (Ü-Tsang) was often at least nominally unified under a series of Tibetan governments in Lhasa, Shigatse, or nearby locations; these governments were at various times under Mongol and Chinese overlordship. The eastern regions of Kham and Amdo often maintained a more decentralized indigenous political structure, being divided among a number of small principalities and tribal groups, while also often falling more directly under Chinese rule after the Battle of Chamdo; most of this area was eventually incorporated into the Chinese provinces of Sichuan and Qinghai. The current borders of Tibet were generally established in the 18th century. Question: Which Chinese provinces used to be the eastern part of Tibet?
answer:
Sichuan and Qinghai


question:
Passage: The Fourteenth Amendment to the United States Constitution (Amendment XIV) is one of the post-Civil War amendments, intended to secure rights for former slaves. It includes the due process and equal protection clauses among others. The amendment introduces the concept of incorporation of all relevant federal rights against the states. While it has not been fully implemented, the doctrine of incorporation has been used to ensure, through the Due Process Clause and Privileges and Immunities Clause, the application of most of the rights enumerated in the Bill of Rights to the states. Question: What has the doctrine of incorporation been used to ensure?
answer:

application of most of the rights enumerated in the Bill of Rights to the states