TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Does the ets-domain transcription factor Spdef promote maturation of goblet and paneth cells in the intestinal epithelium?
Answer: Spdef acts downstream of Math1 to promote terminal differentiation of a secretory progenitor pool into Paneth and goblet cells.

SOLUTION: yes

PROBLEM: Question: Do interictal epileptiform discharges have an independent association with cognitive impairment in children with lesional epilepsy?
Answer: Overall, IED effects on cognition were of a magnitude similar to lesional influences or drug effects (topiramate use). This study demonstrates an association between IEDs and cognitive dysfunction, independent of the underlying focal brain pathology.

SOLUTION: yes

PROBLEM: Question: Do plasma total homocysteine and the methylenetetrahydrofolate reductase 677C > T polymorphism contribute to the distribution of cervico-cerebral atherosclerosis in ischaemic stroke patients?
Answer: Plasma tHcyt level and the MTHFR 677C>T polymorphism do not contribute to the distribution of cervico-cerebral atherosclerosis in ischaemic stroke patients.

SOLUTION:
no