Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Input: Consider Input: Daniel Caligiuri (pronounced (kaliduri); born 15 January 1988 in Villingen-Schwenningen) is a German-born Italian professional footballer who plays as a midfielder for VfL Wolfsburg in the Bundesliga and the Italy national team.

Output: What position was played by Daniel Caligiuri?


Input: Consider Input: Simao Rodrigues de Azevedo (1510, Vouzela, Portugal - 15 June 1579, Lisbon), was a Portuguese Jesuit priest, , one of the co-founders of the Society of Jesus.

Output: To which religious order did Simão Rodrigues belong?


Input: Consider Input: Fostamatinib (R788) is a prodrug rapidly converted to its active metabolite on oral administration. This (known as R406) is a potent inhibitor of spleen tyrosine kinase, required for the expression of a number of proinflammatory cytokines. Fostamatinib has shown significantly superior efficacy (when compared with placebo) in the control of patients with rheumatoid arthritis not responding to methotrexate in Phase II clinical trials. Treatment emergent adverse events with a higher frequency than in those on placebo included diarrhea, hypertension, urinary tract infections, neutropenia and elevated transaminases. The studied doses have shown a linear pharmacokinetic pattern and the administration of methotrexate does not affect it. Fostamatinib may have a role in the therapy of patients with rheumatoid arthritis with poor response to conventional therapy. If these results are confirmed once Phase III studies are completed, it may find a place in the evolving treatment algorithm for rheumatoid arthritis.


Output: Which enzyme is inhibited by a drug fostamatinib?