In this task, you are given a sentence from the research paper and your task is to classify the given sentence into the following categories: Background (Why is this problem important? What relevant works have been created before? What is still missing in the previous works? What are the high-level research questions? How might this help other research or researchers?), Purpose (What specific things do the researchers want to do? What specific knowledge do the researchers want to gain? What specific hypothesis do the researchers want to test?), Method (How did the researchers do the work or find what they sought? What are the procedures and steps of the research?), or Finding (What did the researchers find out? Did the proposed methods work? Did the thing behave as the researchers expected?). 
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Question: with substantial associated costs and morbidity.

Answer: background


Question: Inter-simple sequence repeat ( ISSR ) markers were used to assess the level and distribution of genetic diversity in 226 individuals from 15 populations of H. cordata in China.

Answer: method


Question: This review summarizes the principal findings and the current status on the progress of the development of drugs that interfere with lipid metabolism and function as antivirals against ZIKV.

Answer:
purpose