Given scientific fact as input, generate the question from this fact such that it can be answered from the input.

Ex Input:
Environmental changes is most responsible for the extinction of most species of plants and animals that have lived on earth.

Ex Output:
What process is most responsible for the extinction of most species of plants and animals that have lived on Earth?


Ex Input:
Matter that mechanical wave energy can only travel through is medium.

Ex Output:
What is the name of matter that mechanical wave energy can only travel through?


Ex Input:
Changes to chromosomes that delete, disrupt, or rearrange many loci at once are usually harmful.

Ex Output:

Changes to what that delete, disrupt, or rearrange many loci at once are usually harmful?