Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Input: Consider Input: It is generally accepted that the mitochondria play central roles in energy production of most eukaryotes. In contrast, it has been thought that Plasmodium spp., the causative agent of malaria, rely mainly on cytosolic glycolysis but not mitochondrial oxidative phosphorylation for energy production during blood stages. However, Plasmodium spp. possesses all genes necessary for the tricarboxylic acid (TCA) cycle and most of the genes for electron transport chain (ETC) enzymes. Therefore, it remains elusive whether oxidative phosphorylation is essential for the parasite survival. To elucidate the role of TCA metabolism and ETC in malaria parasites, we deleted the gene for flavoprotein (Fp) subunit, Pbsdha, one of four components of complex II, a catalytic subunit for succinate dehydrogenase activity. The Pbsdha(-) parasite grew normally at blood stages in mouse. In contrast, ookinete formation of Pbsdha(-) parasites in the mosquito stage was severely impaired. Finally, Pbsdha(-) ookinetes failed in oocyst formation, leading to complete malaria transmission blockade. These results suggest that malaria parasite may switch the energy metabolism from glycolysis to oxidative phosphorylation to adapt to the insect vector where glucose is not readily available for ATP production.

Output: Which is the causative agent of malaria?


Input: Consider Input: Urle lie on the western bank of small and shallow Liwiec river and are surrounded by pine forests.

Output: What body of water was Urle next to?


Input: Consider Input: Experience the Colorado River the Hualapai Way! River Runners offers the ONLY One Day Whitewater trip ANYWHERE at the GRAND CANYOU! Since1973,Hualapai River Runners has been conducting whitewater rafting journey to the Colorado River. Our experienced guides expertly sail along the river and share the history of the Canyon and the Hualapai people with you. Visitors experience the excitement of whitewater rapids and then stop to enjoy the impressive beauty of Travertine Falls and a tasty lunch.No charge for children 2 years and under. One-Day Trip Retail$249.00+$79.00(helicopter and round-trip ground transportation) Whitewater rafting tours begin in Peach Springs.Hualapai River Runners transports you to Diamond Creek, which is the starting point for the 37 mile rafting tour. Lunch is included and upon arrival at the rafting tour termination point ,fly out of the Grand Canyon by helicopter to Grand Canyon West. Two-Day Trip Retail$549.00+$79.00(helicopter and round-trip ground transportation) Two-day rafting trips with one night on the Colorado River. All supplies and meals are included. Two days in the Grand Canyon,on the Colorado River allows more time to explore one of the Seven Wonders of the World. Tours Include: *Round-trip transportation from Peach Springs to the starting point and from the termination point back to Peach Springs. *Snack, drinks and lunch(vegetarian meals available upon request) *Waterproof dry bags for storing your cameras, sunscreen, dry clothes, etc. *The helicopter part of transportation is weather permitting. If the helicopter transportation is cancelled because of bad weather, the raft will continue an additional two hours to South Cove and a maximum $20.00 per customer will be given back. Special Website booking rate 15% off rafting in April 2010. So book now! Call us Toll Free Today! Tel: 1-888-868-9378


Output: Where do whitewater rafting tours start?