Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

[Q]: Context: The Browns traveled to Indianapolis to take on an Andrew Luck-led Colts offense. The Colts were able to score in the first quarter as Andrew Luck ran for a 3-yard touchdown making the score 7-0 for the only score of the game. The Browns responded in the 2nd quarter coming within a point when Brandon Weeden found Greg Little on a 14-yard pass (with a failed PAT) making the score 7-6. Then, Luck ran for another touchdown this time from 5 yards out to make the score 14-6 at halftime. The Browns came within a point again in the 3rd quarter as Weeden found Josh Gordon on a 33-yard pass making the score 14-13 but the Colts wrapped things up with Adam Vinatieri's 38-yard field goal followed by a scoreless 4th quarter making the final score 17-13 as the Browns' road record at this point of the season was 0-4 while their record overall was 1-6. 
 Question: Who scored the longest touchdown of the game?
[A]: josh gordon


[Q]: Context: In 2000, the label moved from Brussels to London and was renamed PIAS Recordings. 
 Question: What city is the band PIAS Recordings from?
[A]: brussels


[Q]: Context: CADASIL is a cerebrovascular disease caused by mutations in the NOTCH3 gene. Most mutations result in a gain or loss of cysteine residue in one of the 34 epidermal growth factor-like repeats in the extracellular domain of the Notch3 protein, thus sparing the number of cysteine residues. To date, more than 130 different mutations in the NOTCH3 gene have been reported in CADASIL patients, of which 95% are missense point mutations. Many polymorphisms have also been identified in the NOTCH3 coding sequence, some of them leading to amino acid substitutions. The aim of the present study was to analyze the NOTCH3 gene in a large group of patients affected by leukoencephalopathy and to investigate the presence of genetic variants. The molecular analysis revealed several nucleotide alterations. In particular, we identified 20 different mutations, 22 polymorphisms, and 8 genetic variants of unknown pathological significance never reported previously. We hope that this NOTCH3 gene mutational analysis, performed in such a significant number of unrelated and related patients affected by leukoencephalopathy, will help in molecular screening for the NOTCH3 gene, thus contributing to enlargement of the NOTCH3 gene variation database. 
 Question: Which amino acid residue appears mutated in most of the cases reported with cadasil syndrome?
[A]:
cysteine