Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Q: Context: The smallest front of the war was in Catalonia. In 1689 the Duke of Noailles had led French forces there aimed at bringing further pressure to bear on the Spanish by re-igniting a peasant rising against Charles II, which initially broke out in 1687. Exploiting the situation, Noailles captured Camprodon on 22 May, but a larger Spanish army under the Duke of Villahermosa forced him to withdraw back to Roussillon in August. The Catalan campaign settled down in 1690, but a new front in Piedmont-Savoy proved more eventful. A ferment of religious animosities and Savoyard hatred of the French produced a theatre characterised by massacres and atrocities: constant guerrilla attacks by the armed populace were met by draconian reprisals. In 1690 Saint-Ruth took most of the Victor Amadeus II's exposed Duchy of Savoy, routing the Savoyard army in the process until only the great fortress of Montmelian remained in ducal hands; while to the south in Piedmont, Nicolas Catinat led 12,000 men and soundly defeated Victor Amadeus at the Battle of Staffarda on 18 August. Catinat immediately took Saluzzo, followed by Savigliano, Fossano, and Susa, but lacking sufficient troops, and with sickness rife within his army, Catinat was obliged to withdraw back across the Alps for the winter. 
 Question: What happened first: Catalan campaign settled down or the Battle of Staffarda?

A: catalan campaign settled down
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Q: Context: 4-Day Classic Beijing Tour The 4-day classic Beijing tour is designed for tourists who come to visit China for the first time. It covers the most popular and typical places in Beijing, fully displaying the scenery, culture, history, local lifestyles and features, food and drinks, business, etc. for you. Day 1:Arrival in Beijing Your guide meets you at Capital Airport, and helps you check in at your hotel. Enjoy Beijing Duck as welcome dinner. Accommodation: Beijing downtown Day 2:The Great Wall & the Summer Palace Start your day at the most famous part of the Great Wall, the Badaling Great Wall. Leave the downtown for the Great Wall at 8 am. Since it is a long drive to the Great Wall (about 2 hours' riding) have a break at the Jade Museum on the way. Lunch will be enjoyed in a local restaurant. In the early afternoon come back to the city and have a sightseeing tour of the Summer Palace. Recommended Activity: Beijing Opera Show (Liyuan Theatre, 19:30-21: 10 every evening) Accommodation: Beijing downtown Day 3:Beijing city sightseeing & Local experience Your guide meets you at the hotel at 8 am and set out for the day's touring: Tian'anmen Square and the Forbidden City. After visiting the two sites, have a break and get ready for lunch. Hutong visit: see some traditional arts of the old Beijing, such as paper cutting and kite making, and visit a local family. Accommodation: Beijing downtown Day 4:Beijing Olympic sites Visit the Olympic sites: Bird's Nest, Water Cube and Olympic Park, witnessing the fast developing modern China. Enjoy some free time after visiting the sites. After lunch, it is shopping time and then the tour is over. 
 Question: What does this tour company think can show Beijing is a fast developing modern city?

A: bird's nest, water cube and olympic park.
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Q: Context: Spleen tyrosine kinase (Syk) is an important modulator of immune signaling. The objective of this phase 2 study was to evaluate the efficacy and safety of R788, an oral inhibitor of Syk, in patients with active rheumatoid arthritis despite methotrexate therapy. We enrolled 457 patients who had active rheumatoid arthritis despite long-term methotrexate therapy in a 6-month, double-blind, placebo-controlled trial. The primary outcome was the American College of Rheumatology (ACR) 20 response (which indicates at least a 20% reduction in the number of both tender and swollen joints and improvement in at least three of five other criteria) at month 6. R788, at a dose of 100 mg twice daily and at a dose of 150 mg once daily, was significantly superior to placebo at month 6 (ACR 20 response rates of 67% and 57%, respectively, vs. 35%; P<0.001 for the comparison of both doses with placebo). It was also significantly superior with respect to ACR 50, which indicates at least a 50% improvement (43% and 32% vs. 19%; P<0.001 for the comparison of the 100-mg dose with placebo, P=0.007 for the comparison of the 150-mg dose with placebo) and ACR 70 (28% and 14% vs. 10%; P<0.001 for the comparison of the 100-mg dose with placebo, P=0.34 for the comparison of the 150-mg dose with placebo). A clinically significant effect was noted by the end of the first week of treatment. Adverse effects included diarrhea (in 19% of subjects taking the 100-mg dose of R788 vs. 3% of those taking placebo), upper respiratory infections (14% vs. 7%), and neutropenia (6% vs. 1%). R788 was associated with an increase in systolic blood pressure of approximately 3 mm Hg between baseline and month 1, as compared with a decrease of 2 mm Hg with placebo; 23% of the patients taking R788 vs. 7% of the patients receiving placebo required the initiation of or a change in antihypertensive therapy. In this phase 2 study, a Syk inhibitor reduced disease activity in patients with rheumatoid arthritis; adverse events included diarrhea, hypertension, and neutropenia. Additional studies will be needed to further assess the safety and efficacy of Syk-inhibition therapy in patients with rheumatoid arthritis. (Funded by Rigel; ClinicalTrials.gov number, NCT00665925.) 
 Question: Which enzyme is inhibited by a drug fostamatinib?

A:
spleen tyrosine kinase
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