In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Input: Consider Input: Question: The INR (international normalized ratio) of a patient with chronic atrial fibrillation treated with Acenocoumarol is 4. This result indicates that: 
 Options:  <1> The appearance of ventricular arrhythmias should be controlled. <2> The patient is correctly anticoagulated. <3> Anticoagulation with heparin is more indicated. <4> There is a risk of thrombus formation. <5> Signs of bleeding should be assessed.

Output: 5


Input: Consider Input: Question: When comparing the characteristics of pragmatic or confirmatory clinical studies with explanatory or exploratory clinical studies, which of the following is an advantage of the former? 
 Options:  <1> Information about subgroups of patients representative of the usual clinical practice. <2> Very homogeneous sample, with little variability. <3> Greater capacity to detect differences in the effectiveness of interventions. <4> Greater internal validity <5> Smaller sample size

Output: 1


Input: Consider Input: Question: The Archaea differ from the bacteria in that: 
 Options:  <1> Their membranes have a single phospholipid layer. <2> They have several chromosomes. <3> Their membranes have glycerol ethers. <4> They are not susceptible to viral infection. <5> They do not have a cell wall.


Output: 3