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Question: Wearing curve-hugging black workout pants and a white tank top   Kim Kardashian  perches on a couch in the media room of  her  newly renovated Bel Air estate and sips Pedialyte through a straw. The makeup-free 36-year-old appears almost normal â certainly not like a mogul who  according to Forbes  banked $45.5 million the past year from a brand she built on self-Â­aggrandizement  shameless product peddling and nude selfies. At the epicenter of this unprecedented trajectory remains E!'s Keeping Up With the Kardashians  a living record of her happily debauched family â Kourtney  38; Khloe  33; Rob  30; Kendall  21; and Kylie  20; as well as matriarch Kris  61  and her ex Caitlyn Jenner  67 (who in 2015 transitioned from Bruce). On Sept. 24  a 90-minute special will celebrate the series' 10th unapologetic year. It's a head-scratching milestone for a show that    at  its  conception  offered viewers little more than a voyeuristic lens into the lives of a celebrity-adjacent family â but quickly became the mother ship for all their product extensions and the platform through which Kris and her five daughters ushered in the era of the reality celebrity as a brand.
Keeping Up With the Kardashians now airs in 167 countries  boasts nine spinoffs to date and has ranked as E! Entertainment's top-rated series since 2010. And while it peaked in 2011 with 10.5 million viewers over two nights for  Kim 's fairy-tale wedding to Kris Humphries (they divorced after 72 days)  it still averages north of 2.1 million every Sunday in its 13th season. In 2015  E! agreed to a reported $80 million deal to keep the family through season 14. But that's a pittance compared to the fashion and lifestyle empire they've built from one boutique in the Valley. With a combined social media reach of 700 million-plus followers and five insanely profitable apps  the family mints millions from a hodgepodge of endorsement deals  paid appearances and can't-stay-in-stock products. And it all grew from a show that opened its pilot with these prophetic words from  Kim  (already notorious for the sex tape  she  made with  her  ex  Ray J  that was made public in 2007): "I hate you all."
Kim Kardashian (star  executive producer) I was going to [Pierce College]  and after school I would go work the cash register at our store  Dash. This all happened when I was 27 â¦
Kourtney Kardashian (star  executive producer) We had talked to producers about doing a show about the three of us running the store  Dash  where Khloe and I would do the day-to-day  and  Kim  would come in as a stylist. It didn't go anywhere.
Ted Harbert (then-CEO of E! Networks) Just like anybody else  I knew of the family through [O.J. Simpson attorney] Robert Kardashian. There was a bit of the stuff with  Kim  hanging around Paris Hilton and  of course  the fun with Ray J [who made a sex tape with Kim]. That was sort of world news.
Damla Dogan (senior vp development & programming  E!) They were just crossing over into pop culture territory  especially  Kim .  She  had a look that wasn't on TV at the time.  She  wasn't stick thin  and that was relatable.
 Kim  I don't think any of us thought it would.
Khloe Kardashian (star  executive producer) I don't think we knew what we were even saying yes to. Everything was just super-fast.  Kim  and my mom were steering the ship. We were just like  "Tell us where to be and we'll be there."
Kris The watercooler chatter from the first episode was all about [9-year-old] Kylie jumping on a stripper pole.  Kim  had one installed in my bedroom and our friend Robin Anton  who is the founder of The Pussycat Dolls  was just messing around  and Kylie hops up there  twirls around a couple times  and it became this thing.
 Kim  When we would travel  I remember people calling mine  Kourtney  and Khloe's names and we thought they knew us from high school or something. We just didn't get it. Then they started chasing us down at the airport. That was the first time that we were like  "Oh my God."
Khloe In Armenia  I've never seen so many people. I got separated from  Kim  and everyone  and they all got in the van and left. I was like  "Hello? I'm still in the fucking crowd of people!" Everyone forgot about me and Erin Paxton  our audio mixer  took her boom and literally fished me back into our producer's van.
Kris There was barely Twitter when we started. Ryan called  Kim  and said  "There's this thing called Twitter you might want to pay attention to." The girls [began] embracing their audience and sharing their lives.
 Dow Kim  sort of paved the way for the economic structure of native influencer marketing. Before the rise of the common man YouTuber in their bedroom  you had people like  her .  She  was the one who kicked down the door and got the brands to spend money in that area because  she  showed success. Brands noticed that when when you would pay a celebrity to send out a branded tweet  they were getting more click-throughs for the dollar  so it made more monetary sense. That's why that revolution started.
Dow When  Kim  did the cover of CR [in 2013]  that's when  she  was anointed. It's Carine Roitfeld's magazine  Karl Lagerfeld shot it and Riccardo Tisci art-directed. Fashion washes away all sins. That's when  she  went next-level.
In August 2011   Kim  married NBA player Kris Humphries. The E! special of the $6 million wedding earned the network its highest ratings to date and more than $10 million in ad revenue.
 Kim  There was all this attention on the wedding  and I thought maybe it was just the pressure of the show giving me this anxiety. My friends told me I just had cold feet  but even the producers said  "You don't seem happy. You don't have to go through with this." The night before  my mom pulled me aside  off camera  and was like  "This isn't it for you. Why don't you go away and I'll handle it?" I felt like    if I pulled out now  everyone's going to think I just did  it  for the show. Then afterwards  people were saying  "You have to stay married for a year " but I physically couldn't do  it . When I made the decision [to divorce]  everyone said it was made up for the show. Everyone really wanted to take me down.

Answer: The Kardashian Decade: How a Sex Tape Led to a Billion


Question: Breitbart News Executive Chairman and former White House chief strategist Steve Bannon gave a positive view of the state of the populist economic nationalist movement in an interview published Tuesday  saying the movement is going well but is just getting started.
âI think weâve had a pretty good run so far  and itâs just the top of the first inning â  Bannon  told Good Luck Americaâs Peter Hamby in an interview available exclusively on Snapchat.
 Bannon  has been recruiting candidates to run against establishment Republicans in Senate primaries in 2018  causing panic among GOP leadership.  He  said it was not about a war within the Republican Party  but about a war with the permanent political class.
âThis kind of populist nationalist right has been having this fight with the establishment â  Bannon  said. âTrump was a rejection of the entire establishment. The permanent political class has a business model  and theyâre not prepared to give up power.â
 Bannon  also noted that the establishment Republicans have frequently not had President Trumpâs back and that it is up to the populist right to support Trump in that agenda and make sure it is implemented on Capitol Hill.  He  also said  he  believes Trump is paying more attention to the movement in the wake of Judge Roy Mooreâs defeat of Sen. Luther Strange (R-AL) in the Alabama Republican Senate primary.
 Bannon  said:
I think  he  understood after the primary in Alabama that  his  base believes in a handful of things: They want to build the wall. They want to stop illegal immigration. They still want to get us out of these  what they consider these pointless foreign wars. And I think itâs incumbent on the âdeplorablesâ to be out there.
Asked about whether the populist movement  by going after Republicans  could actually be helping Democrats   Bannon  dismissed those concerns.
âI think this whole thing is evolving â  he  said. âYou have this populist economic nationalism  and itâs just starting to catch on  and I think people who embrace the Trump agenda are going to win primaries and be the best candidates against Democrats.â
On the question of whether  his  influence had been reduced since leaving the White House   Bannon  said  he  has more influence now than  he  did when  he  was serving as a staffer in the West Wing.
âWhen youâre in the White House  you know  youâre just another staffer  and I had a lot of influence â  he  said. âBut thereâs a difference between influence and power  [and] when Iâm out with  Breitbart  and have all my weapons  I can really effect change much more and help the president.â

Answer: Steve Bannon on the State of Populist Economic Nationalism : âItâs Just the Top of the First Inningâ


Question: "Current trends in HIV drug resistance are very concerning " said  Dr. Chris Beyrer   lead author of an overview on the state of global HIV drug resistance.
 Beyrer  is professor of epidemiology with the Johns Hopkins Bloomberg School of Public Health in Baltimore.
 He  and  his  colleagues noted that roughly 19.5 million HIV patients â or approximately half the global population of HIV patients â are now being treated with ART.
That will be "enormously difficult " said  Beyrer .
At the same time   Beyrer  said  those already infected but not yet treated should be given access to newer types of ART "cocktails " including drugs such as dolutegravir that have "higher genetic barriers to resistance."
Drug resistance may ultimately also pose a risk for PrEP  though for the time being  Beyrer  characterizes PrEP resistance as "very rare."

Answer:
Experts concerned that HIV AIDS may be poised for a comeback