In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Example Input: Question: Graphite is a conductor because: 
 Options:  <1> The valence band has electronic vacancies. <2> The driving band has electronic vacancies. <3> Both bands have electronic vacancies. <4> The banned band is very big. <5> The band gap is zero.
Example Output: 5

Example Input: Question: What studies should be performed in an adenocarcinoma with prominent mucinous differentiation of ascending colon diagnosed in a 32-year-old man? 
 Options:  <1> Reorganization of the MYC gene. <2> Analysis of microsatellite instability. <3> Study of mutations of the RET gene. <4> Study of BRCA1-2 mutations. <5> Studies of TP53 mutations.
Example Output: 2

Example Input: Question: Regarding the phases of the clinical development of a drug, which of the following characteristics does NOT correspond to a clinical trial in phase 2? 
 Options:  <1> They are exploratory therapeutic studies. <2> They are performed in a large number of patients (between 100 and 1000). <3> They are used to delimit a range of therapeutic doses. <4> The informed consent of the patients is required for their inclusion in the study. <5> They are usually of short duration.
Example Output:
2