Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

The SET domain contains the catalytic center of lysine methyltransferases that target the N-terminal tails of histones and regulate chromatin function. Here we report the structure of the SET7/9 protein in the absence and presence of its cofactor product, S-adenosyl-L-homocysteine (AdoHcy). A knot within the SET domain helps form the methyltransferase active site, where AdoHcy binds and lysine methylation is likely to occur. A structure-guided comparison of sequences within the SET protein family suggests that the knot substructure and active site environment are conserved features of the SET domain.
What is the characteristic domain of histone methyltransferases?

The first year after birth is called infancy. Infancy is a period when the baby grows very fast. During infancy, the baby doubles in length and triples in weight. Other important changes also happen during infancy: The babys teeth start to come in, usually at about six months of age ( Figure 1.1). The baby starts smiling, paying attention to other people, and grabbing toys. The baby begins making babbling sounds. By the end of the first year, the baby is starting to say a few words, such as mama and dada. The baby learns to sit, crawl, and stand. By the end of the first year, the baby may be starting to walk. Childhood begins after the babys first birthday and continues until the teen years. Between one and three years of age, a child is called a toddler. During the toddler stage, growth is still fast, but not as fast as it was during infancy. A toddler learns many new words. The child even starts putting together words in simple sentences. Motor skills also develop quickly during this stage. By age three, most children can run and climb steps. They can hold crayons and scribble with them. They can also feed themselves and use the toilet. From age three until the teens, growth is slower. The body also changes shape. The arms and legs get longer compared to the trunk. Children continue to develop new motor skills. For example, many young children learn how to ride a tricycle and then a bicycle. Most also learn how to play games and sports ( Figure 1.2). By age six, children start losing their baby teeth. Their permanent teeth begin coming in to replace them. They also start school and learn how to read and write. They develop friendships and become less dependent on their parents. There are numerous milestones that occur during the first few years of childhood. These include the use of language, walking and running, understanding simple concepts, pretend play, the development of fine motor skills, the development of independence, Children develop better motor skills as they get older. having temper tantrums, demonstrating separation anxiety, becoming fully potty-trained, showing natural curiosity.
during infancy, a baby

With regulations in place and DDT banned, the eagle population rebounded. The bald eagle can be found in growing concentrations throughout the United States and Canada, particularly near large bodies of water. In the early 1980s, the estimated total population was 100,000 individuals, with 110,000115,000 by 1992; the U.S. state with the largest resident population is Alaska, with about 40,00050,000, with the next highest population the Provinces and territories of Canada of British Columbia with 20,00030,000 in 1992. Obtaining a precise count of bald eagles population is extremely difficult. The most recent data submitted by individual states was in 2006, when 9789 breeding pairs were reported. For some time, the stronghold breeding population of bald eagles in the lower 48 states was in Florida, where over a thousand pairs have held on while populations in other states were significantly reduced by DDT use. Today, the Contiguous United States with the largest number of breeding pairs of eagles is Minnesota with an estimated 1,312 pairs, surpassing Floridas most recent count of 1,166 pairs. 23, or nearly half, of the 48 contiguous states now have at least 100 breeding pairs of bald eagles. In Washington State, there were only 105 occupied nests in 1980. That number increased by about 30 per year, so that by 2005 there were 840 occupied nests. 2005 was the last year that the Washington Department of Fish and Wildlife counted occupied nests. Further population increases in Washington may be limited by the availability of late winter food, particularly salmon.

Which area had the second highest numbers of bald eagles in 1992?