In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Ex Input:
Question: Point out the correct answer in relation to the monitoring of plasma drug concentrations: 
 Options:  <1> Allergy reactions are related to the dose administered. <2> The extraction of the blood sample must be done once the balance of drug distribution in the organism has been reached. <3> The information provided by the analytical determination of plasma concentration is sufficient to perform the dosage individualization. <4> Only the immunoassay methods are valid for carrying out the analytical determination of the blood samples. <5> It must be done for all drugs that are administered intravenously.

Ex Output:
2


Ex Input:
Question: The use of monolithic columns and continuous beds in liquid chromatography is already very common. To this end: 
 Options:  <1> Microporous membranes are used so that the interaction between a solute and the matrix takes place in the final part of the pore. <2> A separation medium is introduced with a greater degree of continuity than the stationary particle phase so that the mobile phase is forced to traverse the large pores of the medium, improving mass transport. <3> Monodisperse particles are used as a stationary phase in order to improve mass transfer. <4> Flexible organic gels are used from microporous polymers in order to decrease the flow rates. <5> Columns filled with small particles of polymerized silica are used.

Ex Output:
2


Ex Input:
Question: Which of the following is a more reliable marker of malnutrition in the elderly patient? 
 Options:  <1> Weight loss of 1 kg in the last month. <2> Body mass index greater than 24. <3> Difficulty swallowing, chewing and / or lack of appetite. <4> Albumin 4.5 gr / dl. <5> Mini Nutritional Assessment less than 17.

Ex Output:

5