In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[Q]: Question: In the treatment of an overdose of paracetamol is used: 
 Options:  <1> Flumazenil. <2> Edetato sodium calcium. <3> Pralidoxime <4> N-acetylcysteine. <5> Nitro of amyl.
[A]: 4


[Q]: Question: The differential modification of RNA: 
 Options:  <1> It can result in multiple products from one gene. <2> It occurs thanks to the transcription bubble. <3> It is catalyzed by RNA polymerase I. <4> It is catalyzed by RNA polymerase II. <5> It is catalyzed by RNA polymerase III.
[A]: 1


[Q]: Question: When comparing the characteristics of pragmatic or confirmatory clinical studies with explanatory or exploratory clinical studies, which of the following is an advantage of the former? 
 Options:  <1> Information about subgroups of patients representative of the usual clinical practice. <2> Very homogeneous sample, with little variability. <3> Greater capacity to detect differences in the effectiveness of interventions. <4> Greater internal validity <5> Smaller sample size
[A]:
1