Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Input: Consider Input: Luka orevic (Cyrillic: a , born 9 July 1994) is a Montenegrin footballer who plays as a forward for Spanish club SD Ponferradina on loan from FC Zenit Saint Petersburg.

Output: The birth date of Luka Đorđević is what?


Input: Consider Input: "We don't necessarily believe that new advertising, which might make consumers feel better about the Coke brand or better about the ads themselves , will actually result in consumers consuming more of the product," Morgan Stanley's Bill Pecoriello wrote in a research note the days after the investor meeting . But Coke is optimistic it can regain its old magic, and is banking on a new slogan: "Welcome to the Coke side of life." BREAK THROUGH HIT? With PepsiCo about to surpass Coke as the beverage king on Wall Street--Pepsi's market capitalization has _ in recent years to $97.9 billion, putting it less than a billion dollars behind its rival--the heat is on Coke . It's set to launch a new marketing campaign in March, 2006. And having taken a quick look at Coke's investor presentation on Dec. 7 in New York, my sense is that Coke may be moving in the right direction . Given the continued shift by consumers away from soda--Coke's stronghold --and into alternative beverages like juice, tea, and water, Coke badly needs a breakthrough hit. And given that shift away from soda, some analyists wonder whether even the catchiest new ads will be enough to put the fizz back into Coke. SAME OLD, UPDATED? The new flavors of PowerAde sports drink will probably enable Coke to continue stealing market share from PepsiCo's Gatorade brand. And Coke is getting a little more creative with packaging, including new, aluminum bottles of Coke that will be sold in nightclubs, and an 8.4-ounce "100 calorie" version of its flagship Coke that will appeal to women who want fewer calories and will like the fact that the small can will fit in their purse. I doubt whether other new products will be successful, including a new coffee-flavored soda called Coke-Cola Black that I tried. Think carbonated coffee. But I'm not sure if the product, which Coke is pitching as an afternoon pick-me-up for the 35-and-over set, is going to pull people away from their afternoon Frappucino fix. And my opinion is that Vault, an orange-flavored energy drink, will have just as much trouble unseating Mountain Dew among teens as did Coke's last attempt, a product called Surge. If there is one concern I have about the fresh offerings Coke plans to launch this year, it appears that many of them are simply new brands, not new products.

Output: When the middle-aged people feel tired, what would they prefer to drink in order to continue their work?


Input: Consider Input: The mammalian target of rapamycin (mTOR) has been suggested as a target for radiosensitization. Given that radiotherapy is a primary treatment modality for glioblastoma (GBM) and that mTOR is often dysregulated in GBM, the goal of this study was to determine the effects of AZD2014, a dual mTORC1/2 inhibitor, on the radiosensitivity of GBM stem-like cells (GSCs). mTORC1 and mTORC2 activities were defined by immunoblot analysis. The effects of this mTOR inhibitor on the in vitro radiosensitivity of GSCs were determined using a clonogenic assay. DNA double strand breaks were evaluated according to H2AX foci. Orthotopic xenografts initiated from GSCs were used to define the in vivo response to AZD2014 and radiation. Exposure of GSCs to AZD2014 resulted in the inhibition of mTORC1 and 2 activities. Based on clonogenic survival analysis, addition of AZD2014 to culture media 1 hour before irradiation enhanced the radiosensitivity of CD133+ and CD15+ GSC cell lines. Whereas AZD2014 treatment had no effect on the initial level of H2AX foci, the dispersal of radiation-induced H2AX foci was significantly delayed. Finally, the combination of AZD2014 and radiation delivered to mice bearing GSC-initiated orthotopic xenografts significantly prolonged survival as compared with the individual treatments. These data indicate that AZD2014 enhances the radiosensitivity of GSCs both in vitro and under orthotopic in vivo conditions and suggest that this effect involves an inhibition of DNA repair. Moreover, these results suggest that this dual mTORC1/2 inhibitor may be a radiosensitizer applicable to GBM therapy.


Output: What does mTOR stands for?