instruction:
In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
question:
Question: A healthy couple has an 8-year-old daughter with hepatosplenomegaly. The laboratory of biochemical genetics has detected in it a deficiency of the acid beta-glucosidase enzyme (glucocerebrosidase) and molecularly presents the mutation N370S in homozygosis. Which diagnosis is correct? 
 Options:  <1> Fabry disease (Xq22.1). <2> Huntington's disease (4p16.3). <3> Autosomal dominant cerebellar ataxia SCA1 (6p22.3). <4> Adrenoleukodystrophy (Xq28). <5> Gaucher disease (1q22).
answer:
5


question:
Question: A classification of gas chromatography detectors commonly found in the literature divides them into concentration and mass detectors, destructive and non-destructive, integral or differential and universal or selective. According to this classification: 
 Options:  <1> The thermal conductivity detector is a selective detector. <2> The flame ionization detector responds to the concentration of the analyte. <3> The thermal conductivity detector responds to the concentration of the analyte. <4> The phosphorus and nitrogen detector (NPD) is a universal detector. <5> The thermocalorimeter detector is of the differential type.
answer:
3


question:
Question: Intrasubject experimental research designs: 
 Options:  <1> They use independent variables not manipulated directly by the researcher but through the selection of the participants. <2> They are based on the verification of independent groups assigned to the experimental conditions. <3> They combine two independent variables based on the characteristics of the participants. <4> They have lower internal validity than the intersubject designs when they do not use random assignment. <5> They use specific control techniques to control the effects associated with the order of application of the experimental conditions.
answer:

5