In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Example Input: Paragraph: Human adenoviral (HAd) vectors have demonstrated great potential as vaccine vectors. Preclinical and clinical studies have demonstrated the feasibility of vector design, robust antigen expression and protective immunity using this system. However, clinical use of adenoviral vectors for vaccine purposes is anticipated to be limited by vector immunity that is either preexisting or develops rapidly following the first inoculation with adenoviral vectors. Vector immunity inactivates the vector particles and rapidly removes the transduced cells, thereby limiting the duration of transgene expression. Due to strong vector immunity, subsequent use of the same vector is usually less efficient. In order to circumvent this limitation, nonhuman adenoviral vectors have been proposed as alternative vectors. In addition to eluding HAd immunity, these vectors possess most of the attractive features of HAd vectors. Several replication-competent or replication-defective nonhuman adenoviral vectors have been developed and investigated for their potential as vaccine delivery vectors. Here, we review recent advances in the design and characterization of various nonhuman adenoviral vectors, and discuss their potential applications for human and animal vaccination. 
 Title: Development of nonhuman adenoviruses as vaccine vectors
Example Output: False

Example Input: Paragraph: Gram-negative pathogen-induced nosocomial infections and resistance are a most serious menace to global public health. Qingfei Xiaoyan Wan (QF), a traditional Chinese medicine (TCM) formula, has been used clinically in China for the treatment of upper respiratory tract infections, acute or chronic bronchitis and pulmonary infection. In this study, the effects of QF on Pseudomonas aeruginosainduced acute pneumonia in mice were evaluated. The mechanisms by which four typical antiinflammatory ingredients from QF, arctigenin (ATG), cholic acid (CLA), chlorogenic acid (CGA) and sinapic acid (SPA), regulate anti-inflammatory signaling pathways and related targets were investigated using molecular biology and molecular docking techniques. The results showed that pretreatment with QF significantly inhibits the release of cytokines (TNF-α and IL-6) and chemokines (IL-8 and RANTES), reduces leukocytes recruitment into inflamed tissues and ameliorates pulmonary edema and necrosis. In ;6(3):212-221 addition, ATG was identified as the primary anti-inflammatory agent with action on the PI3K/AKT and Ras/MAPK pathways. CLA and CGA enhanced the actions of ATG and exhibited synergistic NF-κB inactivation effects possibly via the Ras/MAPK signaling pathway. Moreover, CLA is speculated to target FGFR and MEK firstly. Overall, QF regulated the PI3K/AKT and Ras/MAPK pathways to inhibit pathogenic bacterial infections effectively. 
 Title: Qingfei Xiaoyan Wan, a traditional Chinese medicine formula, ameliorates Pseudomonas aeruginosa-induced acute lung inflammation by regulation of PI3K/AKT and Ras/MAPK pathways-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Example Output: False

Example Input: Paragraph: : Alcohol dependence; alcoholism; chronic alcohol exposure; alcohol and other drug effects and consequences; genetic factors; environmental factors; brain; neurobiology; translational studies; human studies; animal studies; animal models Vol. 31, No. 3, 2008 215 SOURCE: A and B from Koob, G.F., and Le Moal, M. Drug Addiction, Dysregulation of Reward, and Allostasis. Neuropsychopharmacology 24:97-129, 2001.; C from Koob G.F., Alcoholism: Allostasis and Beyond. Alcoholism: Clinical and Experimental Research 27(2):232-243, 2003. NOTES: ACTH = adrenocorticotrophin; AMYG = amygdala; BNST = bed nucleus of the stria terminalis; CRF = corticotropin-releasing factor; HPC = hippocampus; NE = nore pinephine; PFC, prefrontal cortex; PIT = pituitary gland; PVN = paraventricular nucleus. JOHNSON, R.; PFEFFERBAUM, A.; HART, T.; AND KOPELL, B.S. P300 latency in chronic alcoholics and depressed patients: A preliminary report. In Karrer, R.; Cohen, J.; Tueting, P. Eds. Brain and 
 Title: Translational Studies of Alcoholism Bridging the Gap
Example Output:
True