In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[Q]: Question: The formation of the complex called Aminophylline improves the solubility of one of the following drugs: 
 Options:  <1> Theophylline <2> Digoxin <3> Ampicillin <4> Thioridazine. <5> Ciclosporin
[A]: 1


[Q]: Question: The classical pathway of complement is activated in response to: 
 Options:  <1> Antigen-antibody complexes. <2> Direct binding of C3b to bacterial walls. <3> Microbial glycolipids. <4> Properdin <5> The C-reactive protein.
[A]: 1


[Q]: Question: What happens to the kinetic parameters of a michael enzyme in the presence of a competitive inhibitor ?: 
 Options:  <1> Vmax decreases, Km increases. <2> Vmax decreases, Km decreases. <3> Vmax decreases, Km does not change. <4> Vmax does not vary, Km increases. <5> Vmax does not vary, Km decreases.
[A]:
4