In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Example Input: Question: The reinforcement circuit can be activated by electrical stimulation of the mesolimbic system, originating in the ventral tegmental area and projecting: 
 Options:  <1> To the hippocampus, inhibiting the release of dopamine. <2> To the nucleus accumbens, causing release of dopamine. <3> To the prefrontal cortex, stimulating the release of glutamate. <4> A mesencephalic reticular formation, causing release of glutamate. <5> To the pituitary, inhibiting the release of dopamine.
Example Output: 2

Example Input: Question: JMC, a 14-year-old patient admitted to the Emergency Department. The attending physician considers a blood transfusion necessary. The parents of the patient express their refusal to be given blood, signing the corresponding document of refusal to transfusion. The doctor warns that if the transfusion is not carried out, his life is in danger. They insist on their refusal, the alleged reason for the rejection is basically religious. Which of the following options would be the most correct? 
 Options:  <1> Transfuse the patient. <2> Transfuse the patient, but only when he has lost consciousness. <3> Transfer the case to the healthcare ethics committee so that it adopts the decision. <4> Respect expressed preference and attend without transfusion <5> I would inform the judge and not administer any treatment until the latter indicated it.
Example Output: 5

Example Input: Question: Pyruvate carboxylase: 
 Options:  <1> It requires biotin. <2> Use a methyl group activated as a carbon source. <3> It catalyzes the production of acetyl-CoA and carbon dioxide. <4> It is activated in the muscle during the Cori cycle. <5> It is an intermediate of the citric acid cycle.
Example Output:
1