Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

[Q]: Paragraph: We’ll give the story a “N/A” in this category since it makes clear early on that this research is in the earliest of stages, done in an animal model, and says clearly that clinical trials are a future hope. This is way too early to consider costs which, we assume, would be substantial. The story says the stem cell intervention extended the rodents’ lives “by 10-15% compared to untreated animals.”  At another point, it said, “the mice lived longer than controls, typically several months more, an increase of about 15%.” The story makes no mention of the potential harms that might arise from this approach. Since this has never been tested in humans, we have no idea what they risks are. The story needed to point this out. Theoretically, the stem cells would have to be delivered into human brains via injections, which would make the intervention incredibly risky and possibly a non-starter. In the original paper, the stem cells were injected into the hypothalamus of the mice using viruses as “vectors.” The researchers used lentiviruses, which are used often as vectors for research, but can be deadly in humans. Some discussion of this hurdle also was warranted. The story does a good job at explaining various aspects of the research and depicting the stages through which the research team drew its conclusions. It also is up front about this being animal research, so far untried in humans at even the earliest stages of clinical trials. Of note, the original paper mentions that this study was conducted in very few mice (total of about 20) and only in male mice. That detail would have been useful to include. One thing we wanted to point out that was problematic: The story said “if a similar extension was achieved in humans, a person with a life expectancy of 80 years could live to 92.” We have no idea how this may impact humans; the evidence doesn’t support that kind of speculation. The story doesn’t appear to commit disease mongering, though it could have pointed out that aging in and of itself is not a disease. The story does quote one source unaffiliated with the research and we didn’t detect any conflicts of interest. (The paper itself notes that the authors of the study have no conflicts of interests.) The story is all about basic research that suggests an approach that one day might slow, or possibly reverse, the aging process. There are no real alternatives available now to affect the aging process beyond lifestyle choices that might be healthier and appropriate treatments for illnesses that might otherwise shorten lifespans. It’s clear from the story that this research is preliminary. The story clearly says, “The next step is to create human neural stem cells in the lab for testing.”  It also states that, “Researchers at Albert Einstein College of Medicine in New York hope to launch clinical trials of the procedure soon, but must first produce supplies of human neural stem cells in the lab which can be implanted into volunteers.” The story heralds this research as a “tour de force” and a “breakthrough.” Yet is it accurate in a news story to call anything done in animals a “breakthrough?” That word implies relevance to humans, and this is far from established in a mouse study. Studies in mice are essential but many of them fail to show similar evidence in humans. Likewise, stem cell research is often seen as a magic bullet for some conditions but there have been few cases where the preliminary hope/hype has born out. The story does not appear to rely on a news release. Claim: Stem cell brain implants could 'slow ageing and extend life', study shows
[A]: This story describes some interesting but very early research into the mechanisms of aging and how they might be altered. The story made it clear that this was mouse-level research and has several hurdles to go before it’s ever tested in people. One weak point for the story was how the story assumed there might be benefits in people yet overlooked the potential risks. Considering this intervention involves inserting stem cells into the brain via the assistance of a viral strain known to be harmful to humans, it’s logical to assume there could be some safety concerns. It also overplayed the novelty here by quoting an expert who called it a “tour de force” and a “breakthrough.”  The desire to somehow combat aging seems inherent in humans. If there is a fairly straightforward “switch” that can control the aging process — and this story suggests so — then this would be a major advance. Yet we are looking at decades before this becomes a rigorous Phase III human trial, let alone a potential intervention in humans. The bottom line is: We are talking about approximately 20 male mice.


[Q]: Paragraph: Rather than outline specific recommendations, the 300-page document is meant to be a resource for state regulators as they begin the process in 2020 of drafting formal rules aimed at reducing methane emissions. Despite industry claims that companies have been able to reduce emissions while still setting production records, environmentalists have been pushing hard for more regulations at the state level to target methane leaks and the practice of venting and flaring. The report is the result of numerous meetings over the last four months by the Methane Advisory Panel, a group of more than two dozen experts knowledgeable about various parts of the oil and gas business. The panel included industry representatives, environmental lawyers and experts from Los Alamos National Laboratory, Colorado State University and the New Mexico Institute of Mining and Technology. The discussions centered on topics like compressor engines, storage tanks and pneumatic valves. New Mexico Environment Secretary James Kenney said the effort put into the report is unparalleled in its thoroughness. “This is exactly the baseline information we need to effectively tackle methane emissions in our state,” he said. The state will be accepting public comment on the report through Feb. 20. XTO Energy President Staale Gjervik said the company’s experience shows methane emissions can be mitigated in a cost-effective way but that full industry participation is important. XTO was among those represented on the panel. The report highlights various strategies to reduce emissions, such as switching to low- or no-bleed pneumatic controllers and increasing leak detection and monitoring equipment. The need for more infrastructure also was identified as a possible way to reduce venting and flaring — although the report stated flaring, or the burning off of excess natural gas during extraction, was a necessary part of the process. The state will host public meetings in the coming months to discuss the findings with community members across the state. Stronger regulations for methane emissions will be critical as the oil boom in New Mexico continues, said Hillary Hull of the Environmental Defense Fund, another member of the advisory panel. She said the state’s process in developing the analysis was been inclusive, representing countless hours of research and input from a diverse cross-section of stakeholders. “Next year will be the critical time for moving forward on enforceable, nationally-leading methane rules that protect our air, address the climate crisis and improve education funding for New Mexico families and future generations,” she said. Earlier this month, trade groups representing the oil and gas industries in New Mexico and Texas release an analysis that showed a decline in methane emissions in both states as production tripled. The research also showed that the amount of methane burned off or emitted per barrel of oil equivalent was reduced by 64 percent in the Permian Basin during the past seven years. Meanwhile, the report cited a 210% increase in oil production in the Permian since 2011. Ryan Flynn, executive director at the New Mexico Oil and Gas Association said Permian producers are leading the industry when it comes to environmental practices and emissions reductions. “As energy markets across the globe look to America for their energy needs, we are creating the solutions of the future to deliver cleaner, more reliable energy to people and communities in every corner of the planet,” he said in a statement. Claim: New Mexico releases methane emissions report.
[A]: An advisory panel has released a technical report that covers how emissions are produced by oil and natural gas development and how New Mexico might be able to curb pollution from the industry.


[Q]: Paragraph: It is one of the first times researchers have shown that a truly autonomous surgical robot can navigate inside the heart, not controlled by a doctor with a joystick, according to a study in Wednesday’s journal Science Robotics . Heart surgeons routinely push a thin tube called a catheter through twisting and turning blood vessels to make repairs in the heart without open surgery. But how does a robotic version find its own way through moving heart tissue and with blood swishing in the way? Researchers at Boston Children’s Hospital turned the catheter’s camera tip into essentially an “optical whisker,” said cardiac bioengineering chief Pierre Dupont, the lead researcher. Just as cockroaches navigate along walls and rats reach out with their whiskers, the catheter maps its path through the heart, tapping periodically against the heart’s valve and wall ever so lightly — with about the force of a stick of butter sitting in your hand, Dupont said. The technology combines the camera’s images with machine learning to interpret what tissue it’s touching and how hard. “This robot is trying to walk along the wall of the heart until it gets to the valve,” Dr. Uma Duvvuri of the University of Pittsburgh Medical Center, who heads a robotic innovation lab but wasn’t part of Wednesday’s study. “That’s a pretty exciting development but this is still very, very preliminary.” The demonstration technology is still years away from any operating room, and isn’t designed to replace a surgeon, Dupont said. Instead, he said it might free up a surgeon’s time to focus on harder tasks, comparing it to a plane’s autopilot — and also reduce the time patients and medical staff are exposed to X-rays that currently are needed for navigation. “The easiest part of autonomy in surgery is the technology,” Dupont said. “The hardest parts are the politics, the regulatory” approval and legal efforts. Dupont’s team tested the robotic catheter in 83 procedures in live pigs in a lab. The device found its target, on average taking seconds longer than a doctor threading a catheter into place. But Dupont said the robotic catheter will learn, just like humans, and get better and faster with more practice. Russ Taylor, a medical robotics specialist at Johns Hopkins University, called the technology clever and the study “a significant achievement, but I wouldn’t flag it as a breakthrough.” Robots with different levels of autonomy have been used in surgery for radiation therapy and orthopedics, said Taylor, who wasn’t part of the research. And Pittsburgh’s Duvvuri pointed to studies with a robot that can stitch tissues together without human help. Still, true autonomy, “in my humble opinion, it’s still a hammer looking for a nail,” said Duvvuri, who couldn’t think of an area where it would improve a procedure. And while the new study focused on a potential heart use, Duvvuri said adding that sensing technology to catheters could have other uses, such as helping to diagnose risky growths in the colon. Added Hopkins’ Taylor, “I see things evolving where the machine keeps undertaking more and more discrete tasks while working in partnership with the humans.” ___ Follow Seth Borenstein on Twitter: @borenbears . ___ The Associated Press Health & Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. Claim: Robotic device winds its own way through beating pig heart.
[A]:
Borrowing from the way cockroaches skitter along walls, scientists have created a robotic device that safely guides itself through the delicate chambers of a pig’s heart as it’s beating.