In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Example Input: Question: Acetyl-CoA: 
 Options:  <1> It is synthesized from pyruvate in the eukaryotic cytoplasm. <2> It has a phosphate bond rich in energy. <3> Presents a guanine nucleotide in coenzyme A. <4> Activates pyruvate carboxylase and inhibits pyruvate dehydrogenase. <5> It easily crosses the mitochondrial inner membrane.
Example Output: 4

Example Input: Question: The clinical sensitivity of an analytical parameter (test) is defined as: 
 Options:  <1> The mean concentrations of this test in healthy patients. <2> A pathological concentration of the test in the presence of the disease. <3> A pathological concentration of the test in the absence of the disease. <4> A normal concentration of the test in the absence of the disease. <5> A normal concentration of the test in the presence of the disease.
Example Output: 2

Example Input: Question: The following may occur in multimeric form associated with the J chain: 
 Options:  <1> IgA and IgG. <2> IgD and IgM, <3> IdE and IgD. <4> IgA and IgD. <5> IgA and IgM.
Example Output:
5