In this task, you are given a question and answer options for that question. Using this information, you have to classify each text into different topics: medicine, nursery, psychology, chemistry, pharmacology, biology.

Q: Question: Immunoglobulin isotype change affects: 
 Options:  <0> The constant regions of the heavy chains. <1> The constant regions of the light chains. <2> The totality of heavy chains. <3> The entire immunoglobulin molecule. <4> The hypervariable regions of the heavy chains.

A: biology
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Q: Question: A 72-year-old man with a pathological fracture in the left femur goes to the Emergency Department. After the surgical intervention, the diagnostic study was performed to find out the underlying pathology with the following findings: hemoglobin 9.5 g / dl, total protein 11 g / dl, (VN: 6-8 g / dl), serum albumin 2 g / dl, (VN 3.5-5.0 g / dl), beta 2 microglobulin 6 mg / l (VN 1.1-2.4 mg / l), serum creatinine 1.8 mg / dl (VN: 0 , 1-1.4 mg / dl). Indicate what would be the diagnostic tests necessary to confirm the most probable diagnosis: 
 Options:  <0> Radiological bone series and bone marrow aspiration. <1> Serum and urinary electrophoresis and renal function tests. <2> Bone marrow aspirate and serum calcium concentration. <3> Bone marrow aspiration and serum and urinary electrophoresis. <4> Biopsy of the pathological fracture and radiological bone series.

A: medicine
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Q: Question: Regarding COPD, which one is FALSE? 
 Options:  <0> Smoking is the most important factor in the development of COPD. <1> Contrary to asthma, there is no inflammatory component. <2> The genetic factor to develop better documented COPD is the deficit of alpha1 antitrypsin. <3> Acropachies are not characteristic of COPD and their presence should suggest associated bronchiectasis or bronchopulmonary carcinoma. <4> Spirometrically, obstruction is detected by a FEV1 / FVC ratio of less than 0.70.

A:
medicine
****