TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Is a gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity associated with familial Inappropriate Sinus Tachycardia?
Answer: This is the first report of a gain-of-function HCN4 mutation associated with IST through increased sensitivity to cAMP-dependent activation.

SOLUTION: yes

PROBLEM: Question: Does classical swine fever virus induce oxidative stress in swine umbilical vein endothelial cells?
Answer: Our results indicated that CSFV infection induced oxidative stress in SUVECs. These findings provide novel information on the mechanism by which CSFV can alter intracellular events associated with the viral infection.

SOLUTION: yes

PROBLEM: Question: Do augmentative therapies potentiate the antidepressant-like effects of deep brain stimulation in rats?
Answer: Despite having good predictive validity, animal models are limited from a translational perspective.

SOLUTION:
no