instruction:
Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
question:
Nitrofurantoin-induced acute liver damage in pregnancy.
answer:
adverse drug event


question:
Following intravenous hydration and administration of bicarbonate, the patients' condition resolved without permanent' sequelae.
answer:
non-adverse drug event


question:
Tumor-volume increase at beginning of primary treatment with topical interferon alpha 2-beta in a case of conjunctiva-cornea intraepithelial neoplasia.
answer:

adverse drug event