Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

[Q]: Paragraph: Cancer patients increasingly are having their care guided by gene tumor boards, a new version of the hospital panels that traditionally decided whether surgery, radiation or chemotherapy would be best. These experts study the patient’s cancer genes and match treatments to mutations that seem to drive the disease. “We dissect the patient’s tumor with what I call the molecular microscope,” said Dr. Razelle Kurzrock, who started a board at the University of California, San Diego, where Cairnes is treated. It’s the kind of care many experts say we should aim for — precision medicine, the right drug for the right person at the right time, guided by genes. There are success stories, but also some failures and many questions: Will gene-guided care improve survival? Does it save money or cost more? What kind of gene testing is best, and who should get it? “I think every patient needs it,” especially if cancer is advanced, said Kurzrock, who consults for some gene-medicine companies. “Most people don’t agree with me — yet. In five years, it may be malpractice not to do genomics.” Few people get precision medicine today, said Dr. Eric Topol, head of the Scripps Translational Science Institute. “The only thing that’s gone mainstream are the words.” HOW IT WORKS NOW If you have a cancer that might be susceptible to a gene-targeting drug, you may be tested for mutations in that gene, such as HER2 for breast cancer. Some breast or prostate cancer patients also might get a multi-gene test to gauge how aggressive treatment should be. Then most patients get usual guideline-based treatments. If there’s no clear choice, or if the disease has spread or comes back, doctors may suggest tumor profiling — comprehensive tests to see what mutations dominate. That’s traditionally been done from a tissue sample, but newer tests that detect tumor DNA in blood — liquid biopsies — are making profiling more common. The tests cost about $6,000 and many insurers consider them experimental and won’t pay. Gene tumor boards analyze what the results suggest about treatment. They focus on oddball cases like a breast cancer mutation in a colon cancer patient, or cancers that have widely spread and are genetically complex. The only options may be experimental drugs or “off-label” treatments — medicines approved for different situations. But as tumor profiling grows, it’s revealing how genetically diverse many tumors are, and that oddball cases are not so rare, said Dr. John Marshall. He heads the virtual tumor board at Georgetown Lombardi Comprehensive Cancer Center that also serves cancer centers in Pennsylvania, North Carolina, Michigan and Tennessee. “There is a little bit of faith” that testing will show the right treatment, but it’s not a sure thing, said Dr. Lee Schwartzberg, who heads one participating center, the West Cancer Center in Memphis. Dr. Len Lichtenfeld, the American Cancer Society’s deputy chief medical officer, is optimistic yet wary. Drugs that target BRAF mutations work well for skin cancers called melanomas, but less well for lung or colon cancers. “Just because a mutation occurs it doesn’t mean that drug is going to work in that cancer,” he said. LUCKY CASES When it does, results can be dramatic. Cairnes’ cancer was between her stomach and esophagus, and had spread to her liver, lungs and lymph nodes. Tissue testing found 10 abnormal genes, but on the liquid biopsy only EGFR popped out as a good target. Two drugs aim at that gene but aren’t approved for her type of cancer. A tumor board advised trying both — Erbitux and Tarceva, the drug her husband also had taken. Within two weeks, she quit using pain medicines. After two months, her liver tumor had shrunk roughly by half. There are signs that cancer may remain, but it is under control. She feels well enough to travel and to take care of her granddaughter. “I’m very, very grateful to have a targeted therapy,” Cairnes said. “I cannot expect a better outcome than what we’re seeing right now,” said her doctor, Shumei Kato. WHAT STUDIES SHOW But is gene-guided treatment better than usual care? French doctors did the first big test, with disappointing results. About 200 patients with advanced cancer were given whatever their doctors thought best or off-label drugs based on tumor profiling. Survival was similar — about two months. Another French study, reported in June, was slightly more encouraging on survival but exposed another problem: No drugs exist for many gene flaws. Tests found treatable mutations in half of the 2,000 participants and only 143 got what a tumor board suggested. Some doctors worry that tumor boards’ recommending off-label treatments diverts patients from research that would benefit all cancer patients. For example, the American Society of Clinical Oncology’s TAPUR study tests off-label drugs and shares results with their makers and federal regulators. LETTING PATIENTS CHOOSE Ann Meffert, who lives on a dairy farm in Waunakee, Wisconsin, endured multiple standard treatments that didn’t defeat her bile duct cancer. “She was going to be referred to hospice; there was not much we could do,” said Dr. Nataliya Uboha, who took the case to a tumor board at the University of Wisconsin-Madison. The panel gave several options, including off-label treatment, and Meffert chose a study that matches patients to gene-targeting therapies and started on an experimental one last October. “Two weeks in, I started feeling better,” she said, and when she saw test results, “I couldn’t believe the difference.” Many lung spots disappeared and the liver tumor shrank 75 percent. She is not cured, though, and doctors are thinking about next steps. And that could involve a fresh look at her tumor genes. ___ Marilynn Marchione can be followed at @MMarchioneAP __ This Associated Press series was produced in partnership with the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. Claim: Ultra-personal therapy: Gene tumor boards guide cancer care.
[A]: Doctors were just guessing a decade ago when they gave Alison Cairnes’ husband a new drug they hoped would shrink his lung tumors. Now she takes it, but the choice was no guesswork. Sophisticated gene tests suggested it would fight her gastric cancer, and they were right.


[Q]: Paragraph: "Florida leads the nation in deaths from lightning strikes. But State Farm, one of the nation’s major insurers, says it is Georgia residents who file the most claims for lightning strikes in the country, WSB-TV reported Friday, June 5. PolitiFact Georgia was intrigued and decided to dig a little deeper. We began by contacting Justin Tomczak, a State Farm spokesman. He sent us data showing Georgia was No. 1 in 2014 for lightning-related claims both in number (3,709) and total dollar value ($16.3 million). Texas was second, Alabama at third, Louisiana at fourth and Illinois at fifth. STATE Reported Count Paid Indemnity  Georgia 3,709 $16,301,952 Texas 2,201 $14,160,258 Alabama 1,902 $10,930,264 Louisiana 1,707 $10,930,264 Illinois 1,669 $8,030,507 . ""This is the third year in a row that Georgia has been ranked No. 1,"" Tomczak said. Most of the lightning claims were surge- or power-related, the spokesman said. Damages generally resulted from power surges in electrical wiring, TV cable or phone lines in homes or businesses, he said. As to why Georgia has the most claims, Tomczak said, ""there is no simple answer. However, many of the lightning claims are concentrated in the Southeastern United States, and Georgia has one of the highest populations in this area."" John Jensenius, lightning safety specialist with the National Weather Service, said the population density in metro Atlanta may be a factor in Georgia’s high claim rate. The denser the population the more likely lightning will strike a house, Jensenius said. The Insurance Information Institute, in conjunction with State Farm, compiles a list each year of the top 10 states for homeowners insurance lightning losses by number of claims. In 2013, the institute listed Georgia as highest with 11,184 lightning-related insurance claims from homeowners. Its 2014 report is due out within days, a spokeswoman said. (Georgia was No. 1 for 2012 with 3,844 claims totalling $21.5 million and for 2013 with 2,969 claims totalling $14.9 million, according to State Farm). Nationwide, lightning strikes cost about $674 million in homeowners insurance losses in 2013, down 30.5 percent from 2012, according to the institute. From 2007 to 2011, local fire departments across the country responded to an average of 22,600 fires a year that were started by lightning, according to the National Fire Protection Association. These fires caused an average of $451 million in direct property damage and nine civilian deaths a year, an NFPA analysis shows. Lightning deaths  Florida led the nation for lightning deaths in 2014 with six, followed by Wisconsin with three. Georgia, Arizona, Arkansas, Colorado and Massachusetts each had two deaths. Seven additional states -- California, Michigan, Missouri, Mississippi, New Mexico, Pennsylvania and Texas -- reported one lightning death in the year. The 26 lightning deaths in 2014 followed a record low of 23 set in 2013. The National Weather Service said deaths from lightning strikes averaged 33 a year from 2004 to 2013 and, going back over the last 30 years, an average of 51 people died each year after being hit by lightning. The significant decline in lightning deaths has been attributed to fewer farmers working in the fields, technological advances, improved safety standards and protection. As of the June 1, 2015 there have been six lightning fatalities, two in North Carolina and one each in Iowa, Florida, New Mexico and West Virginia, according to the National Oceanic and Atmospheric Administration (NOAA). WSB-TV meteorologist Brian Monahan said lightning strikes occur most often in Georgia during the summer months when the high pressure area out in the Atlantic around Bermuda pumps in warm, humid air, creating those all-too-familiar afternoon and evening thunderstorms. A secondary spike of lightning strikes also occurs in the severe weather seasons of March to early May and around October and November, when the air is still warm and humid enough to support storms, Monahan said. Our ruling State Farm says Georgia residents file the most claims for lightning strikes in the country. There’s evidence this has been the case last year and the two previous years." Claim: Georgia residents file the most insurance claims for lightning strikes in the country.
[A]: State Farm says Georgia residents file the most claims for lightning strikes in the country. There’s evidence this has been the case last year and the two previous years.


[Q]: Paragraph: The state’s health secretary, Dr. Rachel Levine, announced the death Friday and said Pennsylvania has also reported nine confirmed cases to the Centers for Disease Control and Prevention. The Health Department reported the death on Thursday to the federal agency. State officials aren’t disclosing publicly any other details about the death, such as where or when it occurred. Pennsylvania is also reporting 12 probable cases of vaping-related injury and looking into 63 other cases. The patients have suffered serious lung injuries and most have required hospitalization. Levine is reiterating a recommendation that people do not vape, particularly products that contain THC. Claim: Pennsylvania reports vaping death, investigating injuries.
[A]:
The Pennsylvania Health Department says one person in the state has died from lung injuries associated with vaping and it’s investigating dozens of other suspected or confirmed cases.