Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
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Question: Captopril-associated "pseudocholangitis'.

Answer: adverse drug event


Question: However, we have recently had four cases of clofibrate-induced myopathy in patients with diabetes insipidus due to hypothalamic lesions.

Answer: adverse drug event


Question: Four patients receiving high-dose tamoxifen for greater than 1 year have demonstrated similar retinal changes.

Answer:
adverse drug event