Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[Q]: The apolipoprotein E type 4 allele is a susceptibility gene for late-onset Alzheimer's disease. Apolipoprotein E is found in neurons, some of which contain paired helical filaments made of the microtubule-associated protein tau. Previous studies have demonstrated that the apoE3 isoform, but not the apoE4 isoform, binds tau with high avidity. Because the microtubule-associated protein MAP2c also effects microtubule assembly and stability, we examined interactions between apoE isoforms and MAP2c. Similar to the tau-binding results, apoE3, but not apoE4, bound MAP2c. Binding was detectable down to 10(-9) M MAP2c and 10(-8) M apoE3. Isoform-specific interactions of apoE with the microtubule-associated proteins MAP2c and tau might affect intracellular maintenance of microtubules and could contribute to a time-dependent pathogenesis of Alzheimer's disease.
[A]: Which ApoE isoform is associated with atherosclerosis and Alzheimer's disease?


[Q]: The Kaiser Shipyards were seven major shipbuilding yards located on the U.S. west coast during World War II. Kaiser ranked 20th among United States corporations in the value of wartime production contracts.
[A]: Which industry is Kaiser Shipyards associated with?


[Q]: 30 Herculis (30 Her), or g Herculis, is a star in the constellation Hercules.
[A]:
Which was the constellation for 30 Herculis?