In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Input: Consider Input: Question: The denaturation of proteins: 
 Options:  <1> It is accompanied by the loss of their activity. <2> It supposes the rupture of peptide bonds. <3> It is always an irreversible process. <4> Alter its primary structure. <5> It is carried out by chaperone proteins.

Output: 1


Input: Consider Input: Question: A 55-year-old woman with adrenal insufficiency has been prescribed corticosteroid treatment. Which of the following instructions would you provide in relation to this treatment? 
 Options:  <1> Take the drug first thing in the morning. <2> Take the drug before bedtime. <3> Exclude foods rich in calcium and vitamin D from the diet. <4> Eat a diet low in calories and protein. <5> Monitor the decrease in blood pressure.

Output: 1


Input: Consider Input: Question: The liver converts ethanol into: 
 Options:  <1> Methanol <2> Acetone. <3> Acetaldehyde <4> Hydrogen peroxide. <5> Glycerol.


Output: 3