In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: A healthy couple has an 8-year-old daughter with hepatosplenomegaly. The laboratory of biochemical genetics has detected in it a deficiency of the acid beta-glucosidase enzyme (glucocerebrosidase) and molecularly presents the mutation N370S in homozygosis. Which diagnosis is correct? 
 Options:  <1> Fabry disease (Xq22.1). <2> Huntington's disease (4p16.3). <3> Autosomal dominant cerebellar ataxia SCA1 (6p22.3). <4> Adrenoleukodystrophy (Xq28). <5> Gaucher disease (1q22).
5

Question: Question linked to image nº11 49-year-old patient without a history of interest. He reports a 2-week history of diffuse abdominal pain independent of ingestion and deposition and accompanied by occasional vomiting, malaise and profuse sweating. Analytical: Hb 12 gr / dL. Leucocytes 10x10 ^ 9 / L (Neutrophil 80%, Lymphocytes 15%, Monocytes 3%, Eosinophils 1%). Platelets 270x10 ^ 9 / L. Glucose 100 mg / dL, Urea 80 mg / dL, Creatinine 1.5 mg / dL, A. Uric 12 mg / dL, LDH 7800 IU / L; GOT, GPT and normal alkaline phosphatase. CT: Large mass (16cm) in retroperitoneum infiltrating pancreas, small bowel loops and right kidney. The biopsy is the one shown in the image. Immunohistochemistry: CD20 (+) CD3 (-) bcl 2 (-), CD10 +, bcl 6 (+), P53 (-), TDT (-) Mib1 (proliferation index) 100%. Genetics: rearrangement of 8q24, c-myc gene. Which is the diagnosis? 
 Options:  <1> Diffuse B-cell large lymphoma. <2> Lymphocytic lymphoma <3> Follicular lymphoma 3b. <4> T-cell lymphoma of the intestinal type. <5> Burkitt lymphoma.
5

Question: On the synthesis of proteins it is correct to affirm that: 
 Options:  <1> Start at the carboxyl end. <2> The mRNA is translated from the 5'-end to the 3'-end. <3> In eukaryotes it takes place in the nucleus. <4> The first subunit of the ribosome to bind to the mRNA is the largest. <5> It does not consume energy.

2