TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Is cytoglobin upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer?
Answer: We conclude that the CYGB gene is regulated by both promoter methylation and tumour hypoxia in HNSCC and that increased expression of this gene correlates with clincopathological measures of a tumour's biological aggression.

SOLUTION: yes

PROBLEM: Question: Does phosphoinositide 3-kinase-δ regulate fungus-induced allergic lung inflammation through endoplasmic reticulum stress?
Answer: These findings suggest that PI3K-δ regulates Af-induced steroid-resistant eosinophilic allergic lung inflammation through ER stress.

SOLUTION: yes

PROBLEM: Question: Does methylglyoxal impair endothelial insulin sensitivity both in vitro and in vivo?
Answer: MGO impairs the action of insulin on the endothelium both in vitro and in vivo, at least in part through an ERK1/2-mediated mechanism. These findings may be instrumental in developing novel strategies for preserving endothelial function in diabetes.

SOLUTION:
yes