Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.

The story includes one expert’s estimate of the cost of treating brain and spinal cord defects, but it does not discuss those costs may be affected by folic acid fortification or how the cost of fortification affects food prices. Though individuals don’t face a huge cost, the aggregate cost of fortification is substantial. The story could have mentioned this at least briefly. The story highlights the decline in birth defects that is attributed to folic acid supplementation. However, it does not include a source for the statement that “fortification with the vitamin prevents an estimated 2,000 to 3,000 brain and spinal cord defects in both countries.” By contrast, a CDC web page on folic acid supplementation states that each year in the U.S. “[a]n estimated 1,000 more babies are born healthy since fortification.” http://www.cdc.gov/ncbddd/folicacid/data.html The story performs a service by bringing attention to the complex and difficult balancing of benefits and harms that comes with decisions about adding supplements to food. As mentioned above, the overall thrust of the story adequately captures the basic point that researchers are struggling to determine whether, what, and for whom folic acid supplementation may present potential harm. However, in some cases the comments of Dr. Mason portray a much stronger association between folic acid supplementation and cancer risk than even his own journal publications put forward. By intertwining the researcher’s personal statements with references to published trials and reviews, the story blurs the distinction between speculation and evidence. The story makes clear the complexity of and uncertainty surrounding possible associations between folic acid supplementation and cancer. However, the story exaggerates what is known about potential cancer risk by highlighting comments supporting a potential link with folic acid supplementation, while failing to provide context or contrary information. The story includes an estimate by Dr. Joel Mason that “excess folic acid consumption may cause an extra 15,000 cases of colorectal cancer each year in the U.S. and Canada.” But the story fails to define excess consumption, nor does it note that the are more than 160,000 new cases of colorectal cancer reported in the U.S. and Canada each year. And while the researcher may have told the reporter that he believes supplementation may be boosting cancer rates, a journal article Mason recently co-authored states that “Future studies need to explore whether a causal relationship exists between supraphysiological levels of folate intake and colorectal carcinogenesis.” Also, while the story states that “researchers noticed that rates of colorectal cancer went up in North America around the same time that fortification began,” the reporter should have explained the apparent discrepancy with CDC statements that between 1998 (when mandatory folic acid supplementation began in the U.S.) and 2005 both colorectal cancer incidence and deaths declined. References: Mason article: http://www.ncbi.nlm.nih.gov/pubmed/19057184 Cancer stats: http://www.cdc.gov/cancer/colorectal/statistics/ http://www.cdc.gov/cancer/colorectal/statistics/trends.htm http://www.cancer.ca/Canada-wide/About%20cancer/Cancer%20statistics/Canadian%20Cancer%20Statistics.aspx   A story of this length on a subject that is hotly debated among nutrition researchers should include comments from more than one nutrition researcher. The story fails to note that according to a disclosure statement in one of his recent journal articles, Dr. Mason has been a paid consultant to Wyeth Consumer Healthcare, a manufacturer of multivitamins. Reference: Disclosure statement with Joel B. Mason, Aaron Dickstein, Paul F. Jacques, Paul Haggarty, Jacob Selhub, Gerard Dallal, and Irwin H. Rosenberg A Temporal Association between Folic Acid Fortification and an Increase in Colorectal Cancer Rates May Be Illuminating Important Biological Principles: A Hypothesis Cancer Epidemiol. Biomarkers Prev. 2007 16: 1325-1329. However, because the story does touch on several aspects of the debate, we will give it the benefit of the doubt on this criterion even though we wish other sources had been named or that other nutrition experts had been quoted. The story points out the foods that are fortified with folic acid. However, there is no advice about how individuals could estimate their daily intake of folic acid or alter it, if they desired. The story points out that folic acid supplementation of flour has been required in the U.S. since 1998. It would have been helpful to also discuss whether and how consumers could reduce their intake of folic acid, if desired. Questions about potential harms of folic acid supplementation are indeed a hot topic in nutrition research. However, most of the studies and other reports mentioned in this story were published more than two years ago, so the debate is not as new as the story implies. Given the different aspects of the debate reflected in the story, we think it’s safe to assume this didn’t rely solely or largely on a news release – although we wonder why it relied so heavily on one nutrition expert’s perspectives.
Folic acid might be losing its sheen

Officials in Cumberland County say the Department of Health was told Saturday that a person affiliated with the university was hospitalized with a “possible diagnosis of a bacterial meningitis infection.” They did not say if the ill individual is a student. Officials say they are coordinating with the school and the state to provide antibiotics to anyone who had direct close contact with the individual. The university sent a campus-wide notification Saturday. Meningitis is an infection of the membranes surrounding the brain and spinal cord. The bacteria that cause the infection can spread through kissing, coughing and sharing beverages. Signs and symptoms of infection include high fever, headache, stiff neck and a rash.
Officials investigate possible meningitis case at NC college.

A surgeon washes his hands before enter in an operating room at a hospital in Marseille, France, April 3, 2008. REUTERS/Jean-Paul Pelissier “If you were admitted to hospital tomorrow in any country... your chances of being subjected to an error in your care would be something like 1 in 10. Your chances of dying due to an error in health care would be 1 in 300,” Liam Donaldson, the WHO’s newly appointed envoy for patient safety, told a news briefing. This compared with a risk of dying in an air crash of about 1 in 10 million passengers, according to Donaldson, formerly England’s chief medical officer. “It shows that health care generally worldwide still has a long way to go,” he said. Hundreds of millions of people suffer infections linked to health care each year. Patients should ask questions and be part of decision-making in hospitals, which must use basic hygiene standards and WHO’s checklist to ensure safe surgical procedures were followed. More than 50 percent of acquired infections can be prevented if health care workers clean their hands with soap and water or an alcohol-based handrub before treating patients. Of every 100 hospitalized patients at any given time, 7 in developed and 10 in developing countries will acquire at least one health care-associated infection, according to the United Nations agency. “The longer patients stay in an ICU (intensive care unit), the more at risk they become of acquiring an infection,” it said. Medical devices such as urinary catheters and ventilators are associated with high infection rates. ‘HIGH-RISK BUSINESS’   Each year in the United States, 1.7 million infections are acquired in hospital, leading to 100,000 deaths, a far higher rate than in Europe where 4.5 million infections cause 37,000 deaths, according to WHO. “Health care is a high-risk business, inevitably, because people are sick and modern health care is delivered in a fast-moving, high-pressured environment involving a lot of complex technology and a lot of people,” Donaldson said. A heart operation can involve a team of up to 60 people, about the same number needed to run a jumbo jet, he said. “Infection is a big problem, injuries after falls in hospitals is a big problem and then there are problems that are on a smaller scale but result in preventable deaths. Medication errors are common,” he said. Risk is even higher in developing countries, with about 15 percent of patients acquiring infections, said Dr. Benedetta Allegranzi of the WHO’s “Clean Care is Safer Care” program. “The risk is really higher in high-risk areas of the hospitals, in particular ICUs or neonatal units in developing countries.”   About 100,000 hospitals worldwide now use the WHO’s surgical safety checklist, which the agency said has been shown to reduce surgery complications by 33 percent and deaths by 50 percent. If the checklist is effectively used worldwide, an estimated 500,000 deaths could be prevented each year, it says. “Frankly, if I was having an operation tomorrow I wouldn’t go into a hospital that wasn’t using the checklist because I wouldn’t regard it as safe,” said Donaldson.

Going into hospital far riskier than flying: WHO.