Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Input: Consider Input: Context: The stars that make up a constellation appear close to each other from Earth. In reality, they may be very distant from one another. Constellations were important to people, like the Ancient Greeks. People who spent a lot of time outdoors at night, like shepherds, named them and told stories about them. Figure 26.1 shows one of the most easily recognized constellations. The ancient Greeks thought this group of stars looked like a hunter. They named it Orion, after a great hunter in Greek mythology. The constellations stay the same night after night. The patterns of the stars never change. However, each night the constellations move across the sky. They move because Earth is spinning on its axis. The constellations also move with the seasons. This is because Earth revolves around the Sun. Different constellations are up in the winter than in the summer. For example, Orion is high up in the winter sky. In the summer, its only up in the early morning. Only a tiny bit of the Suns light reaches Earth. But that light supplies most of the energy at the surface. The Sun is just an ordinary star, but it appears much bigger and brighter than any of the other stars. Of course, this is just because it is very close. Some other stars produce much more energy than the Sun. How do stars generate so much energy? Stars shine because of nuclear fusion. Fusion reactions in the Suns core keep our nearest star burning. Stars are made mostly of hydrogen and helium. Both are very lightweight gases. A star contains so much hydrogen and helium that the weight of these gases is enormous. The pressure at the center of a star is great enough to heat the gases. This causes nuclear fusion reactions. A nuclear fusion reaction is named that because the nuclei (center) of two atoms fuse (join) together. In stars like our Sun, two hydrogen atoms join together to create a helium atom. Nuclear fusion reactions need a lot of energy to get started. Once they begin, they produce even more energy. Scientists have built machines called particle accelerators. These amazing tools smash particles that are smaller than atoms into each other head-on. This creates new particles. Scientists use particle accelerators to learn about nuclear fusion in stars. They can also learn about how atoms came together in the early universe. Two well-known accelerators are SLAC, in California, and CERN, in Switzerland. Stars shine in many different colors. The color relates to a stars temperature and often its size. Think about the coil of an electric stove as it heats up. The coil changes in color as its temperature rises. When you first turn on the heat, the coil looks black. The air a few inches above the coil begins to feel warm. As the coil gets hotter, it starts to glow a dull red. As it gets even hotter, it becomes a brighter red. Next it turns orange. If it gets extremely hot, it might look yellow-white, or even blue-white. Like a coil on a stove, a stars color is determined by the temperature of the stars surface. Relatively cool stars are red. Warmer stars are orange or yellow. Extremely hot stars are blue or blue-white. The most common way of classifying stars is by color as shown, in Table 26.1. Each class of star is given a letter, a color, and a range of temperatures. The letters dont match the color names because stars were first grouped as A through O. It wasnt until later that their order was corrected to go by increasing temperature. When you try to remember the order, you can use this phrase: Oh Be A Fine Good Kid, Man. Class O Color Blue Temperature range 30,000 K or more Sample Star An artists depiction of the O class star Zeta Pup- pis. B Blue-white 10,00030,000 K An artists depiction of Rigel, a Class B star. Class A Color White Temperature range 7,50010,000 K Sample Star Sirius A is the brightest star that we see in the night sky. The dot on the right, 
 Question: Which color of star has the highest temperature?

Output: blue


Input: Consider Input: Context: Our previous work has shown that gene knockout of the sodium-glucose cotransporter SGLT2 modestly lowered blood glucose in streptozotocin-diabetic mice (BG; from 470 to 300 mg/dl) and prevented glomerular hyperfiltration but did not attenuate albuminuria or renal growth and inflammation. Here we determined effects of the SGLT2 inhibitor empagliflozin (300 mg/kg of diet for 15 wk; corresponding to 60-80 mgkg(-1)day(-1)) in type 1 diabetic Akita mice that, opposite to streptozotocin-diabetes, upregulate renal SGLT2 expression. Akita diabetes, empagliflozin, and Akita + empagliflozin similarly increased renal membrane SGLT2 expression (by 38-56%) and reduced the expression of SGLT1 (by 33-37%) vs. vehicle-treated wild-type controls (WT). The diabetes-induced changes in SGLT2/SGLT1 protein expression are expected to enhance the BG-lowering potential of SGLT2 inhibition, and empagliflozin strongly lowered BG in Akita (means of 187-237 vs. 517-535 mg/dl in vehicle group; 100-140 mg/dl in WT). Empagliflozin modestly reduced GFR in WT (250 vs. 306 l/min) and completely prevented the diabetes-induced increase in glomerular filtration rate (GFR) (255 vs. 397 l/min). Empagliflozin attenuated increases in kidney weight and urinary albumin/creatinine ratio in Akita in proportion to hyperglycemia. Empagliflozin did not increase urinary glucose/creatinine ratios in Akita, indicating the reduction in filtered glucose balanced the inhibition of glucose reabsorption. Empagliflozin attenuated/prevented the increase in systolic blood pressure, glomerular size, and molecular markers of kidney growth, inflammation, and gluconeogenesis in Akita. We propose that SGLT2 inhibition can lower GFR independent of reducing BG (consistent with the tubular hypothesis of diabetic glomerular hyperfiltration), while attenuation of albuminuria, kidney growth, and inflammation in the early diabetic kidney may mostly be secondary to lower BG. 
 Question: Which protein does empagliflozin inhibit?

Output: sglt2


Input: Consider Input: Context: Pollution that enters water at just one point is called point source pollution. For example, chemicals from a factory might empty into a stream through a pipe or set of pipes (see Figure 21.9). Pollution that enters in many places is called non-point source pollution. This means that the pollution is from multiple sources. With non-point source pollution, runoff may carry the pollution into a body of water. Which type of pollution do you think is harder to control? There are three main sources of water pollution: 1. Agriculture. 2. Industry. 3. Municipal, or community, sources. Huge amounts of chemicals, such as fertilizers and pesticides, are applied to farm fields (see Figure 21.10). Some of the chemicals are picked up by rainwater. Runoff then carries the chemicals to nearby rivers or lakes. Dissolved fertilizer causes too much growth of water plants and algae. This can lead to dead zones where nothing can live in lakes and at the mouths of rivers. Some of the chemicals can infiltrate into groundwater. The contaminated water comes up in water wells. If people drink the polluted water, they may get sick. Waste from livestock can also pollute water. The waste contains bacteria and other organisms that cause disease. In fact, more than 40 human diseases can be caused by water polluted with animal waste. Many farms in the U.S. have thousands of animals. These farms produce millions of gallons of waste. The waste is stored in huge lagoons, like the one in Figure 21.11. Unfortunately, many leaks from these lagoons have occurred. Two examples are described below. In North Carolina, 25 million gallons of hog manure spilled into a nearby river. The contaminated water killed Factories and power plants may pollute water with harmful substances. Many industries produce toxic chemicals. Some of the worst are arsenic, lead, and mercury. Nuclear power plants produce radioactive chemicals. They cause cancer and other serious health problems. Oil tanks and pipelines can leak. Leaks may not be noticed until a lot of oil has soaked into the ground. The oil may pollute groundwater so it is no longer fit to drink. Municipal refers to the community. Households and businesses in a community are also responsible for polluting the water supply. For example: People apply chemicals to their lawns. The chemicals may be picked up by rainwater. The contaminated runoff enters storm sewers and ends up in nearby rivers or lakes. Underground septic tanks can develop leaks. This lets household sewage seep into groundwater. Municipal sewage treatment plants dump treated wastewater into rivers or lakes. Sometimes the wastewater is not treated enough and contains bacteria or toxic chemicals. The oceans are vast. You might think they are too big to be harmed by pollution. But thats not the case. Ocean water is becoming seriously polluted. The oceans are most polluted along coasts. Why do you think thats the case? Of course, its because most pollution enters the oceans from the land. Runoff and rivers carry the majority of pollution into the ocean. Many cities dump their wastewater directly into coastal waters. In some parts of the world, raw sewage and trash may be thrown into the water (see Figure 21.12). Coastal water may become so polluted that people get sick if they swim in it or eat seafood from it. The polluted water may also kill fish and other ocean life. Oil spills are another source of ocean pollution. To get at oil buried beneath the seafloor, oil rigs are built in the oceans. These rigs pump oil from beneath the ocean floor. Huge ocean tankers carry oil around the world. If something goes wrong with a rig on a tanker, millions of barrels of oil may end up in the water. The oil may coat and kill ocean animals. Some of the oil will wash ashore. This oil may destroy coastal wetlands and ruin beaches. Figure 21.13 shows an oil spill on a beach. The oil washed ashore after a deadly oil rig explosion in the Gulf of Mexico in 2010. Thermal pollution is pollution that raises the temperature of water. This is caused by power plants and factories that 
 Question: pollution that enters water in many places


Output: non-point source pollution