TASK DEFINITION: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
PROBLEM: Question: Which of these statements is NOT a characteristic of phase I clinical trials? 
 Options:  <1> They usually have non-therapeutic goals. <2> They can be done in healthy volunteers. <3> They can be done in patients. <4> They are usually randomized. <5> They are usually open.

SOLUTION: 4

PROBLEM: Question: In the activation of the serum complement, the assembly of the Membrane Attack Complex begins with: 
 Options:  <1> C9 <2> C5b. <3> C3a. <4> C6 <5> C8.

SOLUTION: 2

PROBLEM: Question: Grapefruit juice is: 
 Options:  <1> A potent enzyme inducer of cytochrome P450 (CYP3A4). <2> A potent enzyme inhibitor of cytochrome P450 (CYP3A4). <3> A promoter of the absorption of drugs administered orally. <4> An advisable food to increase the bioavailability of drugs of acidic nature. <5> A food without consequence in the kinetics of disposal of drugs eliminated by metabolism in which cytochrome P450 is involved.

SOLUTION:
2