Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Ex Input:
McGill Comedy Club Important meetings today. Discussion on putting on Blazing Saddles. Union room 302, 3-4pm. New members (both actors and non-actors, living and dead) are welcome. History Students' Association Prof. Michael Cross of Dalhouseie University will be speaking on "Unskilled Labor on Rivers and Canals in Upper Canada, 1820-1850: The beginning of Class Struggle" at 10am. in Peacock 230. Design Mirror Sale All types and sizes of design mirrors priced to please. Sale today in Union room 108. McGill Teaching Assistants' Association A general meeting, for all the Tas will be held at 4pm. in peacock 116. Women's Union Important general meeting at 6pm. Union room 423. Speaker on "Importance of Deciding Basic Goals of the Women's Union." Everyone ----old, new and those interviewed, please attend. Film Society Last meeting of the term for all members. All managers are required to be present at 6pm. sharp, Union room 434. Canadian University Students Overseas CUSO presents "Guess Who's Coming to Breakfast" at 7pm. newman Centre, 3848 Peel. Find out about CUSO here and overseas. Everyone welcome.

Ex Output:
If you are interested in arts, where can you go for a visit?


Ex Input:
Early one morning, a taxi pulls up at Tiffany & Co. on Fifth Avenue in New York City, from which elegantly dressed Holly Golightly (Audrey Hepburn) emerges. After looking into the shop's windows, she strolls home. Outside her apartment, she fends off Sid Arbuck (Claude Stroud), her date from the disastrous night before. Later, she is awakened by new neighbor Paul Varjak (George Peppard), ringing her doorbell to get into the building. The pair chat as she dresses to leave for her weekly visit to Sally Tomato (Alan Reed), a mobster incarcerated at Sing Sing prison. Tomato's lawyer, O'Shaughnessy, pays her $100 a week to deliver "the weather report". Audrey Hepburn as Holly Golightly As she is leaving for Sing Sing, Holly is introduced to Paul's "decorator", wealthy older woman Emily Eustace Failenson (Patricia Neal), whom Paul nicknames "2E". That night, Holly goes out onto the fire escape to elude an over-eager date (Mel Blanc). She peeks into Paul's apartment and sees 2E leaving money and kissing Paul goodbye. After 2E leaves, Holly enters Paul's apartment and learns that he is a writer who has not had anything published since a book of vignettes five years before. Holly, in turn, explains that she is trying to save money to support her brother Fred when he gets out of the Army. The pair fall asleep, but are awakened when Holly has a nightmare about Fred. She later buys Paul a typewriter ribbon to apologize and invites him to a party at her apartment. There, Paul meets her Hollywood agent, O. J. Berman (Martin Balsam), who describes Holly's transformation from country girl into Manhattan socialite. He is also introduced to Jose da Silva Pereira (Jose Luis de Vilallonga), a wealthy Brazilian politician, and Rusty Trawler (Stanley Adams), the "ninth richest man in America under 50." In the days that follow, Paul and Holly become closer. One day, 2E enters Paul's apartment, worried that she is being followed. Paul tells her that he will investigate and eventually confronts Doc Golightly (Buddy Ebsen), Holly's estranged husband. Doc explains that Holly's real name is Lula Mae Barnes. They married when she was 13, and he wants to take her back to Texas, as Fred will be returning. After Paul reunites Holly and Doc, she tells Paul the marriage was annulled. At the bus station, she tells Doc she is not going with him. Doc leaves broken-hearted. After drinking at a club, Paul and Holly return to her apartment, where she drunkenly tells him that she plans to marry Trawler for his money. A few days later, Paul learns that one of his short stories will be published. On the way to tell Holly, he sees a newspaper headline stating that Trawler has married someone else. Holly and Paul agree to spend the day together, taking turns doing things that each has never done before. At Tiffany's, Paul has the ring from Doc Golightly's box of Cracker Jack engraved as a present for Holly. After spending the night together, he awakens to find her gone. When 2E arrives, Paul ends their relationship. She calmly accepts, having earlier concluded that he and Holly are in love. Holly schemes to marry Jose for his money, which angers Paul. After Holly receives a telegram notifying her of Fred's death, she trashes her apartment. Months later, Paul has moved out. He is invited to dinner by Holly, who is leaving the next morning for Brazil to continue her relationship with Jose. However, they are arrested in connection with Sally Tomato's drug ring, and Holly spends the night in jail. The next morning, Holly is released on bail and finds Paul waiting, and they take a cab. He has her cat and a letter from Jose explaining he must end their relationship due to her arrest. Holly insists she will go to Brazil anyway, asks the cab to pull over, and releases the

Ex Output:
What city does Holly live in?


Ex Input:
Mutations in the CLN3 gene, which encodes a lysosomal membrane protein, are responsible for the neurodegenerative disorder juvenile Batten disease. A previous study on the yeast homolog to CLN3, designated Btn1p, revealed a potential role for CLN3 in the transport of arginine into the yeast vacuole, the equivalent organelle to the mammalian lysosome. Lysosomes isolated from lymphoblast cell lines, established from individuals with juvenile Batten disease-bearing mutations in CLN3, but not age-matched controls, demonstrate defective transport of arginine. Furthermore, we show that there is a depletion of arginine in cells derived from individuals with juvenile Batten disease. We have, therefore, characterized lysosomal arginine transport in normal lysosomes and show that it is ATP-, v-ATPase- and cationic-dependent. This and previous studies have shown that both arginine and lysine are transported by the same transport system, designated system c. However, we report that lysosomes isolated from juvenile Batten disease lymphoblasts are only defective for arginine transport. These results suggest that the CLN3 defect in juvenile Batten disease may affect how intracellular levels of arginine are regulated or distributed throughout the cell. This assertion is supported by two other experimental approaches. First, an antibody to CLN3 can block lysosomal arginine transport and second, expression of CLN3 in JNCL cells using a lentiviral vector can restore lysosomal arginine transport. CLN3 may have a role in regulating intracellular levels of arginine possibly through control of the transport of this amino acid into lysosomes.

Ex Output:

What is the effect of a defective CLN3 gene?