Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Tardive dyskinesia (TD) is a movement disorder characterized by abnormal involuntary facial movements induced by chronic therapy with classical antipsychotic medications. Currently, there is no satisfactory pharmacotherapy for TD, which represents a major limitation to therapy with classical antipsychotics. In order to develop or optimize therapies for TD, and to develop new APDs with lower indices of motor side effects, the pathology underlying TD must first be understood. The use of animal models has been used to further this objective. Here, we review different preparations that have been used to model TD and discuss the contribution of neuroimaging studies conducted in these models. Studies in animal models have lead to several hypotheses of TD pathology, although none has yet emerged as the ultimate underlying cause of this syndrome. We discuss alterations in functional indices, neuron and synapse morphology and changes in specific neurotransmitter systems that have been described in animal models of TD, and outline how these findings have contributed to our understanding of antipsychotic-induced dyskinesias. We conclude that several non-mutually exclusive theories of TD are supported by animal studies, including increases in oxidative stress leading to structural and functional changes in specific neurotransmitter systems. Elucidating the mechanisms underlying TD neuropathology partly through the use of animal models will lead to the development of APDs with superior side effect profiles or more effective therapies for TD.
What is the cause of Tardive dyskinesia?

USA-100 was launched at 03:40:01 UTC on 10 March 1994, atop a Delta II carrier rocket, flight number D226, flying in the 7925-9.5 configuration.
When was the launch date of USA-100?

I was small for my age. I was shy and sometimes it was hard for me to make friends with the others. However, learning came fairly easy for me. I was the best in most of my classes, but PE class was my nightmare and made me feel that I was not as good as the others. Miss Forsythe was our PE teacher. She was young and energetic. Everyone liked her. She said that we all had to come to her classes. No one could hide from Miss Forsythe! One day she told me that she wanted me to play a game with another girl in a PE show. I was rather worried that I wouldn't do a good job when she explained her idea, but she was excited. With her encouragement, I had no choice but to agree. It was a "boy meets girl" game. I played the boy and my classmate, Margaret Ann, played the girl. We were dressed in evening clothes and danced around the floor. According to Miss Forsythe, I had to pick up Margaret Ann when we finished the dance. Since I was not strong enough to pick the tallest girl up, it was she who picked me up. I suddenly felt ten feet tall! It was a huge success and everybody applauded for our excellent performance. What a wonderful ending! Afterwards, I smiled confidently . Miss Forsythe's understanding and willingness to create a place for me in her show (which certainly did not need me) gave me some much needed confidence. She was and always will be my favorite teacher.

What do we know about Miss Forsythe?