Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: Methotrexate-induced pneumonitis in patients with rheumatoid arthritis and psoriatic arthritis: report of five cases and review of the literature.
Example Output: adverse drug event

Example Input: We report a case of an 11-year-old boy who experienced an anaphylactic reaction after administration of bacitracin ointment.
Example Output: adverse drug event

Example Input: Two patients with osteomyelitis who developed reversible cholestatic jaundice during treatment with oxacillin derivatives are described.
Example Output:
adverse drug event