In this task, you are given a part of an article. Your task is to generate headline (title) for this text. Preferred headlines are under fifteen words.

Radiomics has proven to be a powerful prognostic tool for cancer detection, and has previously been applied in lung, breast, prostate, and head-and-neck cancer studies with great success. However, these radiomics-driven methods rely on pre-defined, hand-crafted radiomic feature sets that can limit their ability to characterize unique cancer traits. In this study, we introduce a novel discovery radiomics framework where we directly discover custom radiomic features from the wealth of available medical imaging data. In particular, we leverage novel StochasticNet radiomic sequencers for extracting custom radiomic features tailored for characterizing unique cancer tissue phenotype. Using StochasticNet radiomic sequencers discovered using a wealth of lung CT data, we perform binary classification on 42,340 lung lesions obtained from the CT scans of 93 patients in the LIDC-IDRI dataset. Preliminary results show significant improvement over previous state-of-the-art methods, indicating the potential of the proposed discovery radiomics framework for improving cancer screening and diagnosis.
Discovery Radiomics via StochasticNet Sequencers for Cancer Detection

In classical machine learning, regression is treated as a black box process of identifying a suitable function from a hypothesis set without attempting to gain insight into the mechanism connecting inputs and outputs. In the natural sciences, however, finding an interpretable function for a phenomenon is the prime goal as it allows to understand and generalize results. This paper proposes a novel type of function learning network, called equation learner (EQL), that can learn analytical expressions and is able to extrapolate to unseen domains. It is implemented as an end-to-end differentiable feed-forward network and allows for efficient gradient based training. Due to sparsity regularization concise interpretable expressions can be obtained. Often the true underlying source expression is identified. INTRODUCTION The quality of a model is typically measured by its ability to generalize from a training set to previously unseen data from the same distribution. In regression tasks generalization essentially boils down to interpolation if the training data is sufficiently dense. As long as models are selected correctly, i. e. in a way to not overfit the data, the regression problem is well understood and can – at least conceptually – be considered solved. However, when working with data from real-world devices, e. g. controlling a robotic arm, interpolation might not be sufficient. It could happen that future data lies outside of the training domain, e. g. when the arm is temporarily operated outside of its specifications. For the sake of robustness and safety it is desirable in such a case to have a regression model that continues to make good predictions, or at least does not fail catastrophically. This setting, which we call extrapolation generalization, is the topic of the present paper. We are particularly interested in regression tasks for systems that can be described by real-valued analytic expression, e. g. mechanical systems such as a pendulum or a robotic arm. These are typically governed by a highly nonlinear function but it is nevertheless possible, in principle, to infer their behavior on an extrapolation domain from their behavior elsewhere. We make two main contributions: 1) a new type of network that can learn analytical expressions and is able to extrapolate to unseen domains and 2) a model selection strategy tailored to the extrapolation setting. The following section describes the setting of regression and extrapolation. Afterwards we introduce our method and discuss the architecture, its training, and its relation to prior art. We present our results in the Section Experimental evaluation and close with conclusions. REGRESSION AND EXTRAPOLATION We consider a multivariate regression problem with a training set {(x1, y1), . . . , (xN , yN )} with x ∈ R, y ∈ R. Because our main interest lies on extrapolation in the context of learning the dynamics of physical systems we assume the data originates from an unknown analytical function (or system of functions), φ : R → R with additive zero-mean noise, ξ, i. e. y = φ(x) + ξ and Eξ = 0. The function φ may, for instance, reflect a system of ordinary differential equations that govern the movements of a robot arm or the like. The general task is to learn a function ψ : R → R that approximates the true functional relation as well as possible in the squared loss sense, i. e. achieves minimal expected error E‖ψ(x) − φ(x)‖2. In practice, we only have particular examples of the function values available and measure the quality of predicting in terms of the empirical error on
EXTRAPOLATION AND LEARNING EQUATIONS

Word alignment is an important natural language processing task that indicates the correspondence between natural languages. Recently, unsupervised learning of log-linear models for word alignment has received considerable attention as it combines the merits of generative and discriminative approaches. However, a major challenge still remains: it is intractable to calculate the expectations of non-local features that are critical for capturing the divergence between natural languages. We propose a contrastive approach that aims to differentiate observed training examples from noises. It not only introduces prior knowledge to guide unsupervised learning but also cancels out partition functions. Based on the observation that the probability mass of log-linear models for word alignment is usually highly concentrated, we propose to use top-n alignments to approximate the expectations with respect to posterior distributions. This allows for efficient and accurate calculation of expectations of non-local features. Experiments show that our approach achieves significant improvements over stateof-the-art unsupervised word alignment methods.

Contrastive Unsupervised Word Alignment with Non-Local Features