Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: On discontinuation of the drug, serum CK concentrations returned to normal within eight days.

Output: non-adverse drug event


Input: Consider Input: All patients improved rapidly after discontinuation of 5-ASA compounds.

Output: non-adverse drug event


Input: Consider Input: Endometrial "sarcomas" complicating ovarian thecoma, polycystic ovarian disease and estrogen therapy.


Output: non-adverse drug event