TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Does a null mutation in ANGPTL8 associate with either plasma glucose or type 2 diabetes in humans?
Answer: Disruption of ANGPTL8 function in humans does not seem to have a large effect on measures of glucose tolerance.

SOLUTION: no

PROBLEM: Question: Does apelin-13 protect the heart against ischemia-reperfusion injury through the RISK-GSK-3β-mPTP pathway?
Answer: The protective mechanism of apelin-13 might be that inactivation of GSK-3β could inhibit the opening of mPTP by activating PI3K/Akt and ERK1/2 involved in the reperfusion injury salvage kinase (RISK) pathway.

SOLUTION: yes

PROBLEM: Question: Does cryopreservation of equine mesenchymal stem cells in 95 % autologous serum and 5 % DMSO alter post-thaw growth or morphology in vitro compared to fetal bovine serum or allogeneic serum at 20 or 95 % and DMSO at 10 or 5?
Answer: Each of the serum sources could be used for short-term cryopreservation of equine bone marrow derived MSCs. Prior to clinical use, clinicians may prefer autologous serum and a lower concentration of DMSO.

SOLUTION:
no