Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Do fat mass and obesity-associated gene polymorphisms affect metabolic response to hormone therapy in healthy postmenopausal women?
Answer: The presence of fat mass and obesity-associated gene risk variants in healthy early postmenopausal women does not adversely affect their response to hormone therapy.

Answer: no


Question: Question: Does mechanical ventilation with lower tidal volumes influence the prescription of opioids or sedatives?
Answer: Concerns regarding sedation requirements with use of lower V(T) are unfounded and should not preclude its use in patients with ALI/ARDS.

Answer: no


Question: Question: Is irinotecan fluorouracil plus leucovorin superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer : results of CALGB 89803?
Answer: The addition of CPT-11 to weekly bolus FU plus LV did not result in improvement in DFS or OS in stage III disease, but did increase both lethal and nonlethal toxicity. This trial demonstrates that advances in the treatment of metastatic disease do not necessarily translate into advances in adjuvant treatment, and it reinforces the need for randomized controlled adjuvant studies.

Answer:
no