TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Does progression rates and sample size estimate for PPMS based on the CLIMB study population?
Answer: Our modern PPMS cohort is demographically similar to previously studied cohorts. PPMS is associated with faster disability accrual than ROMS. Current real-world observations of time to sustained progression will inform design of new clinical trials for PPMS.

SOLUTION: yes

PROBLEM: Question: Are variants in TNFAIP3 , STAT4 , and C12orf30 loci associated with multiple autoimmune diseases also associated with juvenile idiopathic arthritis?
Answer: We have demonstrated associations between JIA and variants in the TNFAIP3, STAT4, and C12orf30 regions that have previously shown associations with other autoimmune diseases, including RA and systemic lupus erythematosus. Our results suggest that clinically distinct autoimmune phenotypes share common genetic susceptibility factors.

SOLUTION: yes

PROBLEM: Question: Is the combination of pill count and self-reported adherence a strong predictor of first-line ART failure for adults in South Africa?
Answer: In this setting, a combination of pill count adherence and self-report adherence questions had the highest diagnostic accuracy for VF. Further validation of this simple, low-cost combination is warranted in large prospective studies.

SOLUTION:
yes