In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: With regard to pyrogens and biotechnological medicines, it is possible to say: 
 Options:  <1> They have no tendency to aggregate or form large units with high molecular weight. <2> Ion exchange chromatography procedures (using their positive charge) can reduce endotoxin levels. <3> Ion exchange chromatography procedures (using their negative charge) can reduce endotoxin levels. <4> Ion exchange chromatography procedures (regardless of their charge) can reduce endotoxin levels. <5> They are unstable under standard autoclaving conditions.
3

Question: Regarding the exploration of psychomotor development, the area of ​​language and sociability in a four-year-old child, which of the following findings can be considered a sign of alarm in the maturation process ?: 
 Options:  <1> Abrupt stop of the acquisition of skills or loss of some already acquired. <2> Hyperactivity He does not know how to entertain himself, he needs constant vigilance. <3> Excessive sociability; he goes with anyone indiscriminately. <4> Repeat questions instead of answering them. <5> All these situations are warning signs.
5

Question: In a patient with Renal Insufficiency, oral drugs must be administered: 
 Options:  <1> With natural fruit juices. <2> With the lowest volume of liquid possible. <3> With the same volume as any other patient. <4> With the largest volume of liquid possible. <5> Always during hemodialysis.

2