In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

Q:  Thus , the potential induction of this gene rearrangement by E1A gene therapy is unlikely to be clinically significant in the treatment of advanced malignant disease .

A: E1A gene
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Q:  Analysis of the 5 ' and 3 ' termini of the transcripts produced in vivo from the puf operon of R . sphaeroides PUF delta 348 - 420 ( three transcripts ; 0 . 59 , 0 . 64 , and 2 . 63 kilobases ) lacking the puf - intercistronic terminator structure were identical to those of the corresponding puf transcripts derived from wild - type R . sphaeroides 2 . 4 . 1 ( four transcripts ; 0 . 50 , 0 . 66 , 0 . 71 , and 2 . 7 kilobases ) showing that the transcripts begin and end at the same sites .

A: puf transcripts
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Q:  On the basis of experiments with mutant virus and transfection with isolated genes , the herpes simplex virus immediate - early gene product ICP4 is known to positively regulate the transcription of viral early and late genes and negatively regulate expression from its own promoter .

A:
early gene
****