Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[EX Q]: Todo Noticias (also known as TN) is an Argentine news cable channel.
[EX A]: Which industry is Todo Noticias associated with?

[EX Q]: Siltuximab, a chimeric monoclonal antibody with high affinity and specificity for interleukin-6, has been shown to enhance anti-multiple myeloma activity of bortezomib and corticosteroid in vitro. We evaluated the safety, pharmacokinetics, immunogenicity, and antitumor effect of siltuximab in combination with bortezomib and dexamethasone in Japanese patients with relapsed or refractory multiple myeloma. This open-label, phase 1, dose-escalating study used two doses of siltuximab: 5.5 and 11.0 mg/kg (administered on day 1 of each 21-day cycle). In total, nine patients were treated. The most common grade 3/4 adverse events, lymphopenia (89 %) and thrombocytopenia (44 %), occurred in patients receiving both doses of siltuximab; however, no dose-limiting toxicities (DLTs) were observed. Following intravenous administration of siltuximab at 5.5 and 11.0 mg/kg, the maximum serum concentration and the area under the curve from 0 to 21 days and from 0 to infinity increased in an approximately dose-proportional manner. Mean half-life, total systemic clearance, and volume of distribution were similar at doses of 5.5 and 11.0 mg/kg. Across both doses, six of the nine patients had complete or partial response (22 and 44 %, respectively). In conclusion, as no DLT was observed, the recommended dose for this combination is 11.0 mg/kg once every 3 weeks. The study is registered at [Link] as NCT01309412.
[EX A]: Which interleukin is blocked by Siltuximab?

[EX Q]: Friction is a force that opposes motion between two surfaces that are touching. Friction can work for or against us. For example, putting sand on an icy sidewalk increases friction so you are less likely to slip. On the other hand, too much friction between moving parts in a car engine can cause the parts to wear out. Other examples of friction are illustrated in Figure 13.7. You can see an animation showing how friction opposes motion at this URL: [Link] Friction occurs because no surface is perfectly smooth. Even surfaces that look smooth to the unaided eye appear rough or bumpy when viewed under a microscope. Look at the metal surfaces in Figure 13.8. The metal foil is so smooth that it is shiny. However, when highly magnified, the surface of metal appears to be very bumpy. All those mountains and valleys catch and grab the mountains and valleys of any other surface that contacts the metal. This creates friction. Rougher surfaces have more friction between them than smoother surfaces. Thats why we put sand on icy sidewalks and roads. The blades of skates are much smoother than the soles of shoes. Thats why you cant slide as far across ice with shoes as you can with skates (see Figure 13.9). The rougher surface of shoes causes more friction and slows you down. Heavier objects also have more friction because they press together with greater force. Did you ever try to push boxes or furniture across the floor? Its harder to overcome friction between heavier objects and the floor than it is between lighter objects and the floor. You know that friction produces heat. Thats why rubbing your hands together makes them warmer. But do you know why the rubbing produces heat? Friction causes the molecules on rubbing surfaces to move faster, so they have more heat energy. Heat from friction can be useful. It not only warms your hands. It also lets you light a match (see Figure 13.10). On the other hand, heat from friction can be a problem inside a car engine. It can cause the car to overheat. To reduce friction, oil is added to the engine. Oil coats the surfaces of moving parts and makes them slippery so there is less friction. There are different ways you could move heavy boxes. You could pick them up and carry them. You could slide them across the floor. Or you could put them on a dolly like the one in Figure 13.11 and roll them across the floor. This example illustrates three types of friction: static friction, sliding friction, and rolling friction. Another type of friction is fluid friction. All four types of friction are described below. In each type, friction works opposite the direction of the force applied to a move an object. You can see a video demonstration of the different types of friction at this URL: (1:07). Static friction acts on objects when they are resting on a surface. For example, if you are walking on a sidewalk, there is static friction between your shoes and the concrete each time you put down your foot (see Figure 13.12). Without this static friction, your feet would slip out from under you, making it difficult to walk. Static friction also allows you to sit in a chair without sliding to the floor. Can you think of other examples of static friction? Sliding friction is friction that acts on objects when they are sliding over a surface. Sliding friction is weaker than static friction. Thats why its easier to slide a piece of furniture over the floor after you start it moving than it is to get it moving in the first place. Sliding friction can be useful. For example, you use sliding friction when you write with a pencil and when you put on your bikes brakes. Rolling friction is friction that acts on objects when they are rolling over a surface. Rolling friction is much weaker than sliding friction or static friction. This explains why it is much easier to move boxes on a wheeled dolly than by carrying or sliding them. It also explains why most forms of ground transportation use wheels, including cars, 4-wheelers, bicycles, roller
[EX A]:
Which type of friction occurs between a paddle and the water?