Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Example Input: You have been badly injured in a car accident. It is necessary to give you a blood transfusion because you lost a great deal of blood in the accident. However, special care must be taken in selecting new blood for you. If the blood is too different from your own, the transfusion could kill you. There are four basic types of blood; A, B, AB, and O. A simple test can make sure of a person's blood type. Everybody is born with one of these four types of blood. Blood type, like hair color1 and height, is received from parents. The four groups must be transfused carefully. A and B cannot be mixed. A and B cannot receive AB, but AB may receive A or B. O can give to any other group; therefore, it is often called the universal donor . For the opposite reason, AB is sometimes called the universal recipient . However, because so many reactions can happen in transfusions , patients usually receive only salt of plasma (liquid part of blood) until their blood can be matched as exactly as possible in the blood bank of a hospital. In this way, it is possible to prevent the transfusion from any bad reactions.
Example Output: People with type A blood can receive type     .

Example Input: In melanoma, transition to the vertical growth phase is the critical step in conversion to a deadly malignant disease. Here, we offer the first evidence that an antioxidant enzyme has a key role in this transition. We found that the antioxidant enzyme peroxiredoxin-2 (Prx2) inversely correlated with the metastatic capacity of human melanoma cells. Silencing Prx2 expression stimulated proliferation and migration, whereas ectopic expression of Prx2 produced the opposite effect. Mechanistic investigations indicated that Prx2 negatively regulated Src/ERK activation status, which in turn fortified adherens junctions function by increasing E-cadherin expression and phospho-Y654-dependent retention of -catenin in the plasma membrane. In murine melanoma cells, Prx2 silencing enhanced lung metastasis in vivo. Interestingly, the natural compound gliotoxin, which is known to exert a Prx-like activity, inhibited proliferation and migration as well as lung metastasis of Prx2-deficient melanoma cells. Overall, our findings reveal that Prx2 is a key regulator of invasion and metastasis in melanoma, and also suggest a pharmacologic strategy to effectively decrease deadly malignant forms of this disease.
Example Output: What type of enzyme is peroxiredoxin 2 (PRDX2)?

Example Input: Mutations in FOXP2 cause developmental verbal dyspraxia (DVD), but only a few cases have been described. We characterize 13 patients with DVD--5 with hemizygous paternal deletions spanning the FOXP2 gene, 1 with a translocation interrupting FOXP2, and the remaining 7 with maternal uniparental disomy of chromosome 7 (UPD7), who were also given a diagnosis of Silver-Russell Syndrome (SRS). Of these individuals with DVD, all 12 for whom parental DNA was available showed absence of a paternal copy of FOXP2. Five other individuals with deletions of paternally inherited FOXP2 but with incomplete clinical information or phenotypes too complex to properly assess are also described. Four of the patients with DVD also meet criteria for autism spectrum disorder. Individuals with paternal UPD7 or with partial maternal UPD7 or deletion starting downstream of FOXP2 do not have DVD. Using quantitative real-time polymerase chain reaction, we show the maternally inherited FOXP2 to be comparatively underexpressed. Our results indicate that absence of paternal FOXP2 is the cause of DVD in patients with SRS with maternal UPD7. The data also point to a role for differential parent-of-origin expression of FOXP2 in human speech development.
Example Output:
Which gene is responsible for proper speech development?