Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.

Ex Input:
The National Health Commission said on Monday that 78 new asymptomatic cases had been identified as of the end of Sunday, compared with 47 the day before. Imported cases and asymptomatic patients, who show no symptoms but can still pass the virus on, have become China’s chief concern after draconian containment measures succeeded in slashing the overall infection rate. Hubei province, the original epicentre, accounted for almost half the new asymptomatic cases. A total of 705 people with asymptomatic cases were under medical observation around mainland China. The surge in asymptomatic cases, which China only began reporting last week, poses a worry as Hubei’s capital Wuhan prepares to allow people to leave the city on April 8 for the first time since it was locked down in late January. Wuhan officials revoked the “epidemic-free” status of 45 residential compounds due to the emergence of asymptomatic cases and other unspecified reasons, according to a report on Monday by the official Xinhua news agency. “Epidemic-free” status allows people living in Wuhan compounds to leave their homes for two hours at a time. China has now reported a total of 81,708 cases, with 3,331 deaths. One new locally transmitted infection was reported in the latest data, in the southern province of Guangdong, down from five a day earlier in the same province. China has closed its borders to foreigners as the virus spreads globally, though most imported cases have involved Chinese nationals returning from overseas. It began testing all international arrivals for the coronavirus from April 1, customs official Song Yueqian said. Of the new cases showing symptoms, 38 entered China from abroad, compared with 25 a day earlier. Of those, 20 arrived in the northeastern province of Heilongjiang from neighbouring Russia. All were Chinese citizens who had flown from Moscow to Vladivostok and travelled to China overland. China will work to prevent cases being imported through land borders, the government said after a meeting chaired by Premier Li Keqiang on Monday，which noted the number of such cases had exceeded cases recorded at airports recently. Those who try to hide their travel history or health condition face a fine of up to 30,000 yuan ($4,230) or even criminal proceedings, Song said, adding such people will be placed on a customs “blacklist” of travellers who will be subject to tighter checks in future. Another possible source of infection are the 1.6 million Chinese who study overseas, many of whom have struggled to return home since international flights were reduced. Charter flights are being arranged to bring home Chinese students in the United States, starting with the youngest, China’s embassy in Washington said. The ambassador, Cui Tiankai, noted in the New York Times on Monday there had been “unpleasant talk” between the two countries about the virus. “But this is not the time for finger-pointing. This is a time for solidarity, collaboration and mutual support,” Cui wrote. Amid criticism China was too slow to warn the international community about the outbreak, Xinhua on Monday published a “detailed timeline” of the country’s coronavirus response and information sharing, from late December 2019 to March 2020. China started reporting to the United States “regularly” on the epidemic and containment measures from Jan. 3, according to the timeline. Click here for an interactive GRAPHIC tracking global spread of coronavirus

Ex Output:
China sees rise in asymptomatic coronavirus cases, to tighten controls at land borders.


Ex Input:
The Associated Press has learned that the attorneys general in Illinois and the District of Columbia are examining how Juul’s blockbuster vaping device became so popular with underage teens. The company’s rapid rise to the top of the multi-billion dollar U.S. e-cigarette market has been accompanied by accusations from parents, politicians and public health advocates that Juul fueled a vaping craze among high schoolers. In addition to the ongoing inquiries in Illinois and the district, which had not been publicly disclosed before, four other state attorneys general are probing or suing Juul. Juul’s top executives have disputed allegations that they’ve marketed their products to teens, declaring that they’ve taken unprecedented steps to combat underage use of its e-cigarettes. The company has shut down its Facebook and Instagram pages and pulled several of its flavored products out of retail stores. Juul also backs federal legislation to raise the minimum age to purchase all tobacco products, including e-cigarettes, to 21 nationwide. Juul spokesman Ted Kwong declined to answer specific questions about the investigations in an emailed statement but reiterated past company steps to prevent youth use. Juul announced Thursday that 50 retail chains have pledged to adopt the company’s age-verification system, which requires sellers to scan a customer’s ID before selling Juul products. Health and Human Services Secretary Alex Azar said in a statement Friday the Trump administration “will continue using every regulatory and enforcement power we have to stop the epidemic of youth e-cigarette use.” A senior Illinois law enforcement official described to AP a wide-ranging inquiry being conducted by the office of Illinois Attorney General Kwame Raoul that is centered on whether Juul violated state consumer fraud laws and other statutes by designing and marketing its products to appeal to underage teens. The official was not authorized to speak publicly and requested anonymity. Marrisa Geller, a spokeswoman for District of Columbia Attorney General Karl Racine, confirmed in an emailed statement an investigation of Juul is underway. She said Racine is concerned about “the dramatic increase in the use of vaping products by district youth” as well as the policies and practices employed by e-cigarette manufacturers to prevent minors from using their products. The attorneys general in Colorado, Connecticut and Massachusetts have announced investigations of Juul related to concerns over underage use of its products. North Carolina’s attorney general filed a lawsuit against Juul in May, asking a court to limit the company’s sales and marketing in the state. All six attorneys general are Democrats. The Food and Drug Administration said last October it seized thousands of documents from Juul’s San Francisco headquarters relating to the company’s marketing. The agency has been investigating whether the company targeted youth with the flavors, design and ingredients of its products. The Wall Street Journal reported Friday that the Federal Trade Commission is investigating Juul’s early marketing campaign and use of social media to promote its products. The FTC declined to comment. Juul has repeatedly stated that it understands the concerns about youth vaping and has taken “the most aggressive actions” of any company in the industry to combat the problem. It has spent millions of dollars on newspaper, radio and online advertisements pledging to keep its products out of the hands of young people. The company also has denied it ever marketed to anyone underage. Kwong said Juul’s earliest marketing campaign, in 2015, was aimed at adults between 25 and 34. Based on the sales and revenue, he said, “there is no evidence that it drove use, youth or otherwise.” Kwong said the company’s paid social media “influencer” program was as a small, short-lived program that ended in 2018. Electronic cigarettes, which have been available in the U.S. since about 2007 and have grown into a more than $6 billion-a-year industry, are battery-powered devices that typically heat a flavored nicotine solution into an inhalable aerosol. Juul, which launched in 2015, now controls roughly three-quarters of the U.S. retail market for e-cigarettes. Last year, one in five U.S. high school students reported vaping in the previous month, according to government survey figures. Most experts agree the aerosol is less harmful than cigarette smoke since it doesn’t contain most of the cancer-causing byproducts of burning tobacco. But there is virtually no research on the long-term effects of the vaping chemicals, some of which are toxic. The Centers for Disease Control and Prevention said Friday that 215 teens and adults in 25 states including Illinois have contracted severe respiratory illnesses after vaping. However, the agency said a clear-cut common cause of the illnesses hasn’t been identified and they are being called “potential cases” that are still under investigation. The CDC said in many of the cases patients had acknowledged they’d recently vaped a substance containing THC, the high-inducing ingredient in marijuana. The agency did not say how many of the patients were teens. Kevin Burns, Juul’s chief executive officer, told “CBS This Morning” on Wednesday the illnesses are “worrisome” for the industry and for Juul “if we contributed to it.” He said the company is in close contact with the CDC to get as much information as it can “so if there’s any issue that was ... associated with us, that we can get to the root cause and understand that.” In Illinois, the state’s Department of Public Health has called e-cigarette use among teens an “epidemic” and said there is an alarming lack of understanding about the risk for nicotine addiction. Other areas being investigated by Raoul’s office include: how Juul verifies the ages of people who make online purchases from the company’s website; the amount of nicotine in the flavored solution and how safe those levels are; and whether Juul has improperly advertised its e-cigarette as a smoking-cessation tool. Kwong said the Juul system is designed to help adult smokers switch from combustible cigarettes and is not intended to be used as a cessation product. Neither Juul nor any other e-cigarette has yet been approved by the FDA to help people who smoke traditional paper-and-tobacco cigarettes quit. The Illinois probe began in the spring. Raoul’s office is not coordinating its investigation with other attorneys general, the official said. Geller, the spokeswoman for Racine, declined to discuss the scope of the district’s inquiry. However, a senior official in Racine’s office wrote to a Juul representative in early February and asked for a trove of information about how district residents purchase the company’s products. Among the data sought by Benjamin Wiseman, director of consumer protection, was a list of authorized retail stores and third-party online retailers that failed to comply with Juul’s rules for preventing minors from buying and using its products. Wiseman also asked that the company “describe in detail the nature of the retailer’s failure to comply” and what action Juul took in response. Racine’s office, Wiseman wrote, learned from news reports and conversations with community members and other government officials that use of Juul’s products by young teenagers in the district has increased dramatically in recent years. “Remarkably, one district high school principal estimates that half of the juniors and seniors at her school are using e-cigarettes, many of which we believe are Juul’s products,” Wiseman told Patrick Lynch, a former attorney general of Rhode Island who runs a lobbying and consulting firm that represents Juul. Lynch’s firm arranged for a meeting in the attorney general’s office last November that included himself, Juul chief administrative officer Ashley Gould, Wiseman and Assistant DC Attorney General Brian Caldwell, according to emails obtained through an open records request. Lynch is not registered as a lobbyist in the District of Columbia. The agenda for the meeting isn’t described in the records, although one email from Lynch said they discussed Juul’s efforts “to dramatically diminish youth access to their product.”

Ex Output:
Juul Labs facing scrutiny from federal and state officials.


Ex Input:
On 5 December 2018, the Seattle Times published an article whose terrifying headline ensured its own virality: “Rare brain-eating amoebas killed Seattle woman who rinsed her sinuses with tap water. Doctor warns this could happen again.” Sadly for those who visited this page hoping to find that the reporting was exaggerated or made-up, this really happened. Though her anonymity was maintained, the story of a 69-year-old Seattle woman who used tap water in her Neti pot for over a year and then died from a Balamuthia mandrillaris brain infection was documented in a 20 September 2018 case study published in the International Journal of Infectious Diseases: We report the case of a 69-year-old female who presented with a chronic nasal skin rash, new onset focal seizure, and a cerebral ring-enhancing lesion after a year of improper nasal irrigation. Despite aggressive and novel anti-amoebic treatment, she died as a result of a Balamuthia mandrillaris brain infection. One year before developing the brain infection, the authors reported, the woman developed a chronic sinus infection whose symptoms were not relieved by medication. She turned to using a Neti pot to rinse her sinuses, but instead of using sterile or saline water as directed, she used tap water filtered with a Brita system. After a month of this practice, and without any relief of her sinus symptoms, “she developed a quarter-sized, red raised rash on the right side of the bridge of her nose and raw red skin at the nasal opening.” Though several misdiagnoses followed, no doctor correctly recognized the rash as a symptom of an amoebic infection. The report stated that a year after that initial rash developed, the woman developed a seizure that required hospitalization. At that time, the doctors identified a lesion on the right side of the brain which they decided to biopsy. Some 19 days later, after a continued decline in the patient’s health, scientists from Johns Hopkins University suggested the possibility that the cause of her malady was an amoebic infection, and the Centers for Disease Control rushed a novel drug for her treatment. Unfortunately, they were unable to halt the progression of the disease, and the patient’s family made the decision to remove her from life support. An autopsy determined the cause of death to be Granulomatous Amebic Encephalitis (GAE), which the CDC defines as “a serious infection of the brain and spinal cord that typically occurs in persons with a compromised immune system.” In this case, the causative agent was an extremely rare amoeba named Balamuthia mandrillaris, one of three forms of amoeba known to be capable of infecting and consuming the human brain. Amoebas are a broad group of taxonomically mixed unicellular organisms that consume surrounding cellular material through absorption, and that express an ability to take on a variety of shapes. Several different species are associated with disease, most notably Naegleria fowleri, commonly known as the “brain-eating amoeba” that can cause a different kind of brain infection called primary amebic meningoencephalitis (PAM). Balamuthia mandrillaris was discovered in 1986 in the brain of a mandrill monkey during an autopsy at the San Diego Zoo and is now recognized to be a cause of GAE in both humans, several primates, and other animals, with an estimated 200 cases of human infection ever documented. The amoebae are ubiquitous in soil and groundwater although their presence is not expected in city-treated water, according to Liz Coleman, a spokeswoman for the Environmental Public Health division of Washington State’s Department of Health, quoted in the Seattle Times’ reporting. Merely ingesting the thing will not lead to health problems, but in rare cases (usually instances involving people with weakened immune systems, or those who are young or old), the organisms can infect a host through skin breakage or via the respiratory system. If they infect the central nervous system, they “ingest bits and pieces of host tissue [and produce] enzymes that degrade the tissue.” Nasal irrigation involves rinsing one’s sinus cavity with distilled or sterile water (or water that has been filtered to remove potentially infectious organisms), and one such method of water delivery is a Neti pot. The need for sterility is explicitly stated due to the (extremely small) risk posed by another amoeba, Naegleria fowleri, and it is the reason the FDA requires (in the absence of sterile water) a specific kind of filter capable of removing the amoeba and similarly-sized organisms from water before it is pushed through fragile sinus tissue. While the authors of this case report could not state with absolute certainty that the Neti pot was to blame, it is far and away the most likely explanation given the fact that the patient had been rinsing her sinuses with tap water regularly for an extended period of time: While it is recommended that only sterile water or saline be used … the patient used tap water that was filtered with a Brita Water Purifier … Improper nasal irrigation has been reported as a method of infection for the comparably insidious amoeba, N. fowleri. This precedent led us to suspect the same route of entry for the Balamuthia amoeba in our case. Although this hypothesis is consistent with the patient’s history and ultimate diagnosis, the water supply to the patient’s home was not tested, hence our ability to definitively trace the patient’s infection to improper nasal lavage is limited. Other routes of exposure are possible, according to a 2013 review of amoebic infections: Epidemiology of Balamuthia GAE is not well understood. However, based on several case reports it can be hypothesized that gardening, playing with dirt, or exposure to dust while motorcycling may play significant roles in the acquisition of Balamuthia infection. It has been shown that Balamuthia is found in the soil and dust in air and the route of infection is probably via inhalation of Balamuthia either present in soil or carried by the wind or the amebae entering the body through a cut or puncture. Once it gains entry into the body it is likely to spread hematogenously to the brain. Additionally, there is some indication that water may serve as a vehicle for acquiring the infection. Although the water used in the Neti pot likely caused this infection, Dr. Cynthia Maree, a co-author of the report and a member of the team that treated the woman in question, told the Seattle Times that “the risk of infection to the brain is extremely low,” adding that “people who use neti pots or other nasal-irrigation devices can nearly eliminate [that risk] by following directions printed on the devices, including using only saline or sterilized water.”

Ex Output:

A woman who rinsed her nasal passages using a neti pot filled with tap water contracted a fatal “brain-eating” amoeba infection.