Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
Three cases are described in which periorbital topical corticosteroids appear to have resulted in raised intraocular pressure or glaucoma.

Ex Output:
non-adverse drug event


Ex Input:
Osteomyelitis occurring during infliximab treatment of severe psoriasis.

Ex Output:
adverse drug event


Ex Input:
Methemoglobinemia: an occupational hazard of phenylpropanolamine production.

Ex Output:

adverse drug event