Given scientific fact as input, generate the question from this fact such that it can be answered from the input.

Example Input: Interstitial fluid are all hormones secreted into before entering the circulatory system.
Example Output: Where are all hormones secreted into before entering the circulatory system?

Example Input: Activities that can reduce the effects of edema condition include exercises to keep the blood and lymph flowing through affected areas.
Example Output: Activities that can reduce the effects of what condition include exercises to keep the blood and lymph flowing through affected areas?

Example Input: The mass of atoms is based on the number of protons and neutrons in nucleus.
Example Output:
The mass of atoms is based on the number of protons and neutrons in what?