In this task, you need to Translate Czech text to English.
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Question: Obal (1) pro materi l, jako kapaliny nebo sypk  jemn  granul ty, sest v  z vnit°n ho dut ho t lesa  (2) z plastick  hmoty pro balen² materi l, kter  je v cehrann , a z man etov ho pl  t  (3) z kartonu, kter² obklopuje dut  t leso (2) a je na n m tvarov  pevn  fixov n, k  emu  m  dut  t leso  (2) nejm n  jeden vn j   okrajov² z hyb (6, 7) v rohov  oblasti, odpov daj c  v cehrann  oblasti (8, 9) pl  t  (3), kter  je pro aretaci do n j vlo iteln , uspo° dan  symetricky k rohov  skl dac    °e  (10) pl  t  (3) a s pl  t m (3) spojen  nejm n  jednou nap°   k   °e (10) uspo° dan  razic    ry  (11e, 11d) a nejm n  dvou ve tvaru p smene V k sob  navz jem uspo° dan²ch skl dac ch  ar (11a, 11b), jeho  podstatou je,  e pro spolehliv  upevn n  mezi dut²m t lesem (2) a pl  t m (3) je v cehrann  oblast (8, 9) pl  t  (3)  ty°·heln kov , p°i em  skl dac    ry (11a, 11b) p°ech zej  do dvou v ostr m ·hlu se sb haj c ch razic ch  ar (11d, 11e) a rohov² z hyb (6, 7) je v p°izp soben  na tuto oblast (8, 9) pl  t  (3) omezen rovn²mi plochami (6a).\

Answer: In the present invention there is disclosed a pack (1) for containing pourable goods such as liquids and small free-flowing granules, said pack comprising an inner, polygonal blown plastic container (2)  accommodating the goods to be packaged, and a sleeve-like cardboard jacket (3), which surrounds the blown plastic container (2) and is positively fixed thereto, for which purpose the blown plastic container (2) is formed in one corner with at least one indentation (6, 7) in its outer edge to which corresponds a polygonal part (8, 9) of the cardboard jacket (3), which is designed to fold inwards during assembly for locking purposes and which is arranged symmetrically to a corner fold line (10) of the jacket (3), being connected to the jacket (3) via at least one die-cut line (11e, 11d) extending substantially transversely of the corner fold line and at least two fold lines (11a, 11b) arranged in the shape of a V to one another, wherein the improvement is characterized in that: the polygonal part (8, 9) of the jacket (3) in the unfolded state is made quadrangular, the V-shaped fold lines (11a, 11b) have free ends individually connected to one end of two straight die-cut lines(11e, 11d), respectively, the other ends of said two die-cut lines (11e, 11d) are joined together at a median point above the V-shaped fold lines (11a, 11b), and that the corner-shaped indentation (6, 7) of said container (2) is bordered by flat surfaces (6a) for snugly receiving said polygonal part (8, 9) of said jacket (3).


Question: Předkládaný vynález se týká bicyklických heterocyklů, které  jsou užitečné pro léčbu buněčné proliferace, jako je rakovina a  restenóza a rovněž angiogenéze a ateroskleróza. Bicyklické  sloučeniny podle vynálezu jsou silnými inhibitory na cyklinu  závislých kináz (cdks), růstovým faktorem zprostředkovaných  kináz a nereceptorových kináz. Sloučeniny se snadno připraví  a mohou být podány různými cestami, včetně orální cestou a  mají dostatečnou biologickou dostupnost pro klinické použití.  Vynález poskytuje sloučeniny obecného vzorce I, kde Z je N  nebo CH; Gje N nebo CH; W je NH, SO nebo SO2, R1  zahrnuje fenyl a substituovaný fenyl, R2 zahrnuje alkyl a  cykloalkyl, R3 zahrnuje alkyl a vodík, R8 a R9 zahrnují vodík a  alkyl a jejich farmaceutické prostředky, obsahující sloučeninu  obecného vzorce I společně s farmaceuticky přijatelným  nosičem, ředidlem nebo excipientem.

Answer: The present invention relates to bicyclic heterocycles which are used herein  are useful for treating cell proliferation such as cancer and  restenosis as well as angiogenesis and atherosclerosis. Bicyclic  the compounds of the invention are potent inhibitors of cyclin  dependent kinases (cdks), a growth factor mediated  kinases and non-receptor kinases. The compounds are readily prepared  and may be administered by a variety of routes, including by the oral route and  have sufficient bioavailability for clinical use.  The invention provides compounds of formula I wherein Z is N  or CH; G is N or CH; W is NH, SO or SO 2, R 1  includes phenyl and substituted phenyl, R 2 includes alkyl and  cycloalkyl, R 3 includes alkyl and hydrogen, R 8 and R 9 include hydrogen and  alkyl and pharmaceutical compositions thereof comprising a compound  of Formula I together with pharmaceutically acceptable  carrier, diluent or excipient.


Question: 1-[4-(5-Kyanoindol-3-yl)butyl]-4-(2-karbamoylbenzofuran-5-yl)piperazinu nebo jeho fyziologicky přijatelných solí je použito k výrobě léčiva k léčení subtypu úzkostných poruch ze souboru zahrnujícího subtypy panické poruchy s  agorafobií nebo bez agorafobie, agorafobii, obsesivně-kompulzivní poruchy, sociální fobii, posttraumatickou stresovou poruchu, indikaci akutního stresu a obecnou úzkost, bipolárních poruch, manie, demence, závislosti na návykových látkách, sexuálních dysfunkcí, poruch přijímání potravy, obezity, anorexie a fibromyalgie. Výhodnou solí je 1-[4-(5-kyanoindol-3-yl)butyl]-4-(2-karbamoylbenzofuran-5-yl)piperazinhydrochlorid.ŕ

Answer:
In the present invention, there is disclosed the use of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine or physiologically acceptable salts thereof for the preparation of a medicament for the treatment of sub-type anxiety disorders being selected from the group consisting of the panic disorder sub-types with or without agoraphobia, agoraphobia, obsessive-compulsive spectrum disorder, social phobia, posttraumatic stress disorder, acute stress indication or generalized-anxiety disorder, bipolar disorders, mania, dementia, addictive substance-related disorders, sexual dysfunctions, eating disorders, obesity, anorexia and fibromyalgia, whereby preferred salt is represented by 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine hydrochloride.