TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Is s100A8/A9 involved in host defense against murine urinary tract infection?
Answer: We show that despite high S100A8/A9 expression in bladder and kidney tissue upon UTI, S100A8/A9 does not contribute to an effective host response against E. Coli in the urinary tract system.

SOLUTION: no

PROBLEM: Question: Does interaction of programmed death-1 and programmed death-1 ligand-1 contribute to testicular immune privilege?
Answer: The constitutive expression of PD-L1 in the testis is an important mechanism underlying testicular immune privilege and long-term survival of intratesticular islet allografts.

SOLUTION: yes

PROBLEM: Question: Does increased proteoglycan synthesis in cartilage in experimental canine osteoarthritis reflect a permanent change in chondrocyte phenotype?
Answer: Previous results indicated that PG synthesis and turnover in articular cartilage was increased for many months after induction of experimental OA. Our present results show that the enhanced rate of PG synthesis and turnover were evident in freshly explanted tissue, but the differences were lost over 3 days in culture. A decreased responsiveness to TNF alpha was also lost. The hypermetabolic activity of experimental OA chondrocytes was thus reversible and not a permanent change in chondrocyte phenotype.

SOLUTION:
no