Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: In all the patients, pellagra symptoms appeared during isoniazid therapy.
Example Output: adverse drug event

Example Input: INTRODUCTION: Despite high success rates with free-tissue transfer, flap loss continues to be a devastating event.
Example Output: non-adverse drug event

Example Input: Incidence of myopathy in patients treated with antimalarials.
Example Output:
non-adverse drug event