Given scientific fact as input, generate the question from this fact such that it can be answered from the input.
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Question: In prokaryotes, a(n) genome is composed of a single, double-stranded dna molecule in the form of a loop or circle.

Answer: In prokaryotes, what is composed of a single, double-stranded dna molecule in the form of a loop or circle?


Question: The pupil is the name of the black opening in the eye that lets light enter.

Answer: What is the name of the black opening in the eye that lets light enter?


Question: Insignificant type of role does cartilage play in the human skeleton.

Answer:
What type of role does cartilage play in the human skeleton?