This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

Despite being an original story, Spectre draws on Ian Fleming's source material, most notably in the character of Franz Oberhauser, played by Christoph Waltz. Oberhauser shares his name with Hannes Oberhauser, a background character in the short story "Octopussy" from the Octopussy and The Living Daylights collection, and who is named in the film as having been a temporary legal guardian of a young Bond in 1983. Similarly, Charmian Bond is shown to have been his full-time guardian, observing the back story established by Fleming. With the acquisition of the rights to Spectre and its associated characters, screenwriters Neal Purvis and Robert Wade revealed that the film would provide a minor retcon to the continuity of the previous films, with the Quantum organisation alluded to in Casino Royale and introduced in Quantum of Solace reimagined as a division within Spectre rather than an independent organisation.
Which actor portrayed Franz Oberhauser?

Studies by Nathaniel Kleitman in 1938 and by Derk-Jan Dijk and Charles Czeisler in the 1990s put human subjects on enforced 28-hour sleep–wake cycles, in constant dim light and with other time cues suppressed, for over a month. Because normal people cannot entrain to a 28-hour day in dim light if at all,[citation needed] this is referred to as a forced desynchrony protocol. Sleep and wake episodes are uncoupled from the endogenous circadian period of about 24.18 hours and researchers are allowed to assess the effects of circadian phase on aspects of sleep and wakefulness including sleep latency and other functions.[page needed]
What time cycle did studies in 1938 and 1990s use on humans?

Given that water contamination is a major means of transmitting diarrheal disease, efforts to provide clean water supply and improved sanitation have the potential to dramatically cut the rate of disease incidence. In fact, it has been proposed that we might expect an 88% reduction in child mortality resulting from diarrheal disease as a result of improved water sanitation and hygiene. Similarly, a meta-analysis of numerous studies on improving water supply and sanitation shows a 22–27% reduction in disease incidence, and a 21–30% reduction in mortality rate associated with diarrheal disease.

What is a major means of the spread of diarrhea disease?