instruction:
In this task, you are given a question and a context passage. You have to answer the question based on the given passage.
question:
What needs to decrease before pituitary growth hormone can increase in the blood?, Context: In addition to the negative consequences of sleep deprivation, sleep and the intertwined circadian system have been shown to have strong regulatory effects on immunological functions affecting both the innate and the adaptive immunity. First, during the early slow-wave-sleep stage, a sudden drop in blood levels of cortisol, epinephrine, and norepinephrine induce increased blood levels of the hormones leptin, pituitary growth hormone, and prolactin. These signals induce a pro-inflammatory state through the production of the pro-inflammatory cytokines interleukin-1, interleukin-12, TNF-alpha and IFN-gamma. These cytokines then stimulate immune functions such as immune cells activation, proliferation, and differentiation. It is during this time that undifferentiated, or less differentiated, like naïve and central memory T cells, peak (i.e. during a time of a slowly evolving adaptive immune response). In addition to these effects, the milieu of hormones produced at this time (leptin, pituitary growth hormone, and prolactin) support the interactions between APCs and T-cells, a shift of the Th1/Th2 cytokine balance towards one that supports Th1, an increase in overall Th cell proliferation, and naïve T cell migration to lymph nodes. This milieu is also thought to support the formation of long-lasting immune memory through the initiation of Th1 immune responses.
answer:
cortisol, epinephrine, and norepinephrine


question:
What did NBC delay for the west coast primetime?, Context: CBC's sports coverage has also attained high viewership in border markets, including its coverage of the NHL's Stanley Cup Playoffs, which was generally considered to be more complete and consistent than coverage by other networks such as NBC. Its coverage of the Olympic Games also found a significant audience in border regions, primarily due to the fact that CBC aired more events live than NBC's coverage, which had been criticized in recent years for tape delaying events to air in primetime, even if the event is being held in a market in the Pacific Time Zone during primetime hours on the East (where it would still be delayed for West coast primetime).
answer:
Olympic Games


question:
Who paid heavily for the Plymouth Blitz?, Context: In the First World War, Devonport was the headquarters of Western Approaches Command until 1941 and Sunderland flying boats were operated by the Royal Australian Air Force. It was an important embarkation point for US troops for D-Day. The city was heavily bombed by the Luftwaffe, in a series of 59 raids known as the Plymouth Blitz. Although the dockyards were the principal targets, much of the city centre and over 3,700 houses were completely destroyed and more than 1,000 civilians lost their lives. This was largely due to Plymouth's status as a major port Charles Church was hit by incendiary bombs and partially destroyed in 1941 during the Blitz, but has not been demolished, as it is now an official permanent monument to the bombing of Plymouth during World War II.
answer:

more than 1,000 civilians lost their lives