Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

[Q]: Paragraph: The Sackler family owns Purdue Pharma, the privately held drug company that has made billions from OxyContin, and Sacklers hold most of the seats on the board. Members of the family have been accused in a case brought by the state of Massachusetts of deceiving patients and doctors about the drug’s risks as deaths mounted. And documents recently released in the case shine new light on former Purdue Pharma President Richard Sackler’s role in the aggressive marketing of the powerful opioid. As the allegations mount, family members who made their fortunes well before OxyContin even went on the market have sought to distance themselves from their relatives. At the same time, activists have called on institutions to cut ties with the Sacklers, staging protests at museums that have received millions in donations. “The Sackler name is becoming synonymous with the opioid epidemic, and it is damning for these institutions to have their name up,” said Nan Goldin, a photographer whose works have been displayed at Harvard’s Arthur M. Sackler Museum and at New York’s Metropolitan Museum of Art, which has a Sackler Wing. Lost in the outrage: One of the most generous and best known of the Sacklers died in 1987, nearly a decade before OxyContin was released. Arthur M. Sackler made his money from medical research, medical advertising and trade publications. His younger brothers, Raymond and Mortimer, bought out his stake after he died. Arthur Sackler’s name is on a gallery at the Smithsonian, a wing of galleries at London’s Royal Academy of Arts and a museum at Beijing’s Peking University. The Sackler Wing at the Met, which houses the celebrated Temple of Dendur from ancient Egypt, was funded by all three brothers. Richard has likewise donated heavily to various institutions. After a federal investigation, Purdue Pharma and three executives — none of them Sacklers — pleaded guilty in 2007 and agreed to pay more than $600 million for misleading the public about the risks of OxyContin. The Stamford, Connecticut, company has also been hit with a multitude of lawsuits over its role in the opioid crisis that killed more than 47,000 people in 2017 alone. Arthur’s nephew, Richard Sackler, who became president of Purdue Pharma in 1999 and remains on the board, is at the center of the litigation. He and other current and former executives have been accused of hiding the dangers of the drug from doctors and patients, encouraging physicians to prescribe more of the highest doses and minimizing the abuse crisis as it was unfolding. “This is not too bad. It could have been far worse,” he wrote to Purdue Pharma executives in 2001 after a federal prosecutor reported that 59 people in one state had died from OxyContin, according to documents released this week in the Massachusetts case. At the launch party for OxyContin in 1996, Richard Sackler boasted the drug would bring a “blizzard of prescriptions that will bury the competition,” the documents say. Years later, they say, he sought to shift blame onto drug users themselves, recommending the company “hammer on the abusers in every way possible.” “Richard followed that strategy for the rest of his career: collect millions from selling addictive drugs, and blame the terrible consequences on the people who became addicted,” attorneys in Massachusetts Attorney General Maura Healey’s office wrote. “By their misconduct, the Sacklers have hammered Massachusetts families in every way possible. And the stigma they used as a weapon made the crisis worse.” A spokesman for Richard Sackler’s family referred questions about the lawsuit to the company. Purdue Pharma said in a statement that Massachusetts’ case — the first one brought by a state to personally name members of the Sackler family — is “littered with biased and inaccurate characterizations.” The company said it will “aggressively defend against these misleading allegations.” Arthur Sackler’s widow and children insist that they never financially benefited from the sale of OxyContin. “It is a gross injustice to connect Arthur to the opioid crisis some 30 years after his death when he had nothing to do with it,” Dame Jillian Sackler said in a statement. “It denies the many important contributions he made working to improve world health and to build cultural bridges between peoples.” But activists have made no distinction between Arthur and his relatives. In July, dozens of activists led by Goldin held a protest inside the Arthur M. Sackler Museum at Harvard, scattering pill bottles and holding banners that read “SHAME ON SACKLER.” Similar demonstrations have been held at the Met and the Smithsonian. Goldin, who was addicted OxyContin for years, said that getting the institutions to act will be difficult. “Who is going to turn down the money? They offer millions to these institutions, and the board members are not necessarily committed to action, so it’s going to take a lot,” she said. A Met spokesman said that the Sackler family’s support began decades before the opioid crisis, but that the museum will be examining its gift acceptance policies. The Guggenheim, home to the Sackler Center for Arts Education, had no comment. A Harvard spokesman said in an email that Arthur Sackler’s donation in 1982 paid for the construction of the building that originally housed the museum but that his foundation does not fund the museum. ___ Associated Press reporter Verena Dobnik contributed to this report from New York. ___ Follow Alanna Durkin Richer at http://www.twitter.com/aedurkinricher Claim: Opioid crisis brings unwanted attention to wealthy family.
[A]: The Sackler name is emblazoned on the walls at some of the world’s great museums and universities, including the Smithsonian, the Guggenheim and Harvard. But now the family’s ties to OxyContin and the painkiller’s role in the deadly opioid crisis are bringing the Sacklers a new and unwanted kind of attention and complicating their philanthropic legacy.


[Q]: Paragraph: The state Supreme Judicial Court said in an order released Friday that Monday’s planned court hearing in an appeal brought by the Vapor Technology Association will be postponed until further notice. The court is awaiting the results of new vaping regulations the state plans to issue next week before making a decision on the case. Republican Gov. Charlie Baker last week signed into law new restrictions on flavored tobacco and vaping products and promised to rescind the state’s emergency ban of the sale of all vaping products. Baker said the state’s Public Health Council will meet Wednesday to adopt new regulations as part of the new state law, at which point he’ll lift the emergency ban. The ban was imposed in September and set to last until the end of December. Neighboring Rhode Island also has a temporary ban on the sale of flavored vaping products. Democratic Gov. Gina Raimondo signed an executive order in September and the health department issued emergency regulations Oct. 4 to implement a four-month ban, with an optional two-month extension. Rhode Island lawmakers have said they’ll address vaping in the next legislative session, which begins in January. Democratic Gov. Ned Lamont of Connecticut is trying to figure out how to regulate vaping, after expressing an interest in banning flavored vaping products. A new law recently took effect in Connecticut that increased the age to 21 for someone to purchase vaping products. Claim: Massachusetts high court delays hearing on vaping ban suit.
[A]: Massachusetts’ highest court is holding off hearing arguments in the vaping industry’s challenge of the state’s temporary ban on vapor products.


[Q]: Paragraph: One new study found that heart attack survivors benefited from a medicine long used to treat gout. Several experimental drugs also showed early promise for interfering with heart-harmful genes without modifying the genes themselves — in one case, with treatment just twice a year. The research was featured at an American Heart Association conference ending Monday in Philadelphia. “There’s a lot of excitement” about the new gene-targeting medicines, especially because they seem to last so long, said Dr. Karol Watson, of the University of California, Los Angeles. Scientists have been exploring gene therapy — altering DNA — to attack the root cause of many diseases. The new drugs essentially accomplish the same thing without tampering with genes, said the University of Pennsylvania’s Dr. Daniel Rader, who has consulted for some makers of these drugs. The medicines work by silencing or blocking messages that genes give to cells to make proteins that can do harm, such as allowing cholesterol to accumulate. The first few of these “RNA-interference” drugs recently were approved for other conditions, and research is also targeting heart disease. Farthest along is inclisiran, tested in 1,561 people with heart disease from clogged arteries who still had high LDL, the bad form of cholesterol, despite taking standard drugs. They were given a shot of inclisiran or a dummy drug when they joined the study, three months later and then every six months. The drug lowered LDL by 56% without serious side effects. More testing will show whether it also lowers heart attacks and other problems, not just cholesterol. Inclisiran’s maker, The Medicines Company, plans to seek federal approval for it later this year. Two other RNA interference drugs aim at a different target — triglycerides, another fat in the blood that’s elevated in one quarter of Americans. Treatments include very low-fat diets, weight loss, fish oil and drugs, but doctors say more and better therapies are needed. Each RNA interference drug was tested at various doses in 40 people. A single shot lowered triglycerides by 30% to 67%, and the benefit lasted for at least four months. The studies were just intended to show safety; Arrowhead Pharmaceuticals is developing both drugs. Other research found new benefits from older drugs. AstraZeneca’s Farxiga, originally developed to treat diabetes, also lowered the risk of heart problems in heart failure patients who did not have diabetes. Among 2,605 of such patients treated for 18 months, about 9% of those on Farxiga had worsening heart failure or heart-related death versus nearly 13% of those not given the drug. That worked out to a 27% lower risk, without extra serious side effects. Surprising benefits also were seen in a Canadian study of the decades-old gout drug. The anti-inflammatory drug colchicine — sold as Colcrys, Mitigare and in generic form — was tested in 4,745 people who recently had a heart attack. After about two years, colchicine users had a 23% lower risk of suffering a new heart attack, heart-related death, stroke, cardiac arrest or urgent need for an artery-opening procedure compared with a group given dummy pills. The benefit came mostly from preventing strokes and artery-opening procedures, and some heart doctors would rather have seen more difference in heart attacks and deaths. Colchicine is being tested in several other studies, and more evidence is needed before using it routinely to lower heart risks, Dr. L. Kristin Newby of Duke University wrote in a commentary published with the study in the New England Journal of Medicine. Dr. Donald Lloyd-Jones, a Northwestern University cardiologist and program chief for the heart conference, was more supportive. “When you have a safe drug that’s easily available, it’s going to be hard to hold this one back,” he said. ___ Marilynn Marchione can be followed on Twitter at http://twitter.com/MMarchioneAP ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. Claim: New, old drugs may offer fresh ways to fight heart disease.
[A]:
Novel drugs may offer fresh ways to reduce heart risks beyond the usual medicines to lower cholesterol and blood pressure.