instruction:
In this task, you are given a sentence in the English language. Your job is to translate the English sentence into the Spanish language.
question:
During protein turnover, which of the following molecules binds to the proteins marking them for degradation by the proteasome ?
answer:
Durante el recambio proteico, ¿cuál de las siguientes moléculas se une a las proteínas marcándolas para su degradación por el proteasoma?


question:
48 year old woman In a mammographic screening study, a group of suspicious microcalcifications was detected in the upper external quadrant of the right breast. Percutaneous biopsy assisted by vacuum in a prone table. The anatomopathological diagnosis is of G II intraductal carcinoma. You propose a surgical exeresis of the lesion with radiological marking (harpoon). The anatomopathological study of the surgical piece reports infiltrating ductal carcinoma of 6 mm (RE ++ 100%, RP ++ 100%, Ki-67 10%, Her-2 negative) associated with intraductal component. Free surgical edges. You report the result to the patient. What would you propose?
answer:
Mujer de 48 años de edad. En estudio mamográfico de screening se detecta un grupo de     microcalcificaciones    sospechosas     en cuadrante superoexterno de mama derecha. Se realiza biopsia percutánea asistida por vacío en mesa prono. El diagnóstico anatomopatológico es de carcinoma intraductal G II. Usted propone una exéresis quirúrgica de la lesión con marcaje radiológico       (arpón).       El       estudio anatomopatológico de la pieza quirúrgica informa de carcinoma ductal infiltrante de 6 mm (RE ++ 100%, RP ++ 100%, Ki-67 10%, Her-2 negativo) asociado a componente intraductal. Bordes quirúrgicos libres. Usted informa del resultado a la paciente. ¿Qué le propondría?


question:
If a 17-year-old boy with compulsive symptoms appears in his office, along with motor and multiple vocal tics, what disorder would he think of as the first diagnostic option?
answer:

Si se presenta en su consulta un chico de 17 años con síntomas compulsivos, junto con tics motores y vocales múltiples, ¿en qué trastorno pensaría como primera opción diagnóstica?