Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does creatine supplementation affect kidney function in an animal model with pre-existing renal failure?
Answer: Creatine supplementation at a dosage of 2% w/w for 4 weeks does not impair kidney function in animals with pre-existing renal failure or in control animals.
no

Question: Do norepinephrine and ephedrine counteract the increase in cutaneous microcirculation induced by spinal anaesthesia?
Answer: Improved skin perfusion induced by spinal anaesthesia was not counteracted by the use of norepinephrine or ephedrine.
no

Question: Do matrix metalloproteinase-8 inhibitors mitigate sepsis-induced myocardial injury in rats?
Answer: MMP-8 inhibitor attenuated myocardial injury in septic rats, which might be related to reduced expression of TNF-α and IL-1β.

yes