Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Q: Context: Facioscapulohumeral muscular dystrophy (FSHD) is one of the most prevalent adult muscular dystrophies. The common clinical signs usually appear during the second decade of life but when the first molecular dysregulations occur is still unknown. Our aim was to determine whether molecular dysregulations can be identified during FSHD fetal muscle development. We compared muscle biopsies derived from FSHD1 fetuses and the cells derived from some of these biopsies with biopsies and cells derived from control fetuses. We mainly focus on DUX4 isoform expression because the expression of DUX4 has been confirmed in both FSHD cells and biopsies by several laboratories. We measured DUX4 isoform expression by using qRT-PCR in fetal FSHD1 myotubes treated or not with an shRNA directed against DUX4 mRNA. We also analyzed DUX4 downstream target gene expression in myotubes and fetal or adult FSHD1 and control quadriceps biopsies. We show that both DUX4-FL isoforms are already expressed in FSHD1 myotubes. Interestingly, DUX4-FL expression level is much lower in trapezius than in quadriceps myotubes, which is confirmed by the level of expression of DUX4 downstream genes. We observed that TRIM43 and MBD3L2 are already overexpressed in FSHD1 fetal quadriceps biopsies, at similar levels to those observed in adult FSHD1 quadriceps biopsies. These results indicate that molecular markers of the disease are already expressed during fetal life, thus opening a new field of investigation for mechanisms leading to FSHD. 
 Question: Which disease is associated with the ectopic expression of the protein encoded by the gene DUX4?

A: fshd
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Q: Context: Mercury is the smallest planet. It has no moon. The planet is also closest to the Sun and appears in Figure 25.7. As Figure 25.8 shows, the surface of Mercury is covered with craters, like Earths Moon. The presence of impact craters that are so old means that Mercury hasnt changed much geologically for billions of years. With only a trace of an atmosphere, it has no weather to wear down the ancient craters. Because Mercury is so close to the Sun, it is difficult to observe from Earth, even with a telescope. The Mariner 10 spacecraft did a flyby of Mercury in 19741975, which was the best data from the planet for decades. In 2004, the MESSENGER mission left Earth. On its way to Mercury it did one flyby of Earth, two of Venus and three of Mercury. In March 2011, MESSENGER became the first spacecraft to enter an orbit around Mercury. During its year-long mission, the craft will map the planets surface and conduct other studies. One of these images can be seen in Figure 25.9. Mercury is named for the Roman messenger god. Mercury was a messenger because he could run extremely fast. The Greeks gave the planet this name because Mercury moves very quickly in its orbit around the Sun. Mercury orbits the Sun in just 88 Earth days. Mercury has a very short year, but it also has very long days. Mercury rotates slowly on its axis, turning exactly three times for every two times it orbits the Sun. Therefore, each day on Mercury is 58 Earth days long. Mercury is very close to the Sun, so it can get very hot. Mercury also has virtually no atmosphere. As the planet rotates very slowly, the temperature varies tremendously. In direct sunlight, the surface can be as hot as 427C (801F). On the dark side, the surface can be as cold as 183C (297F)! The coldest temperatures may be on the insides of craters. Most of Mercury is extremely dry. Scientists think that there may be a small amount of water, in the form of ice, at the planets poles. The poles never receive direct sunlight. Figure 25.10 shows a diagram of Mercurys interior. Mercury is one of the densest planets. Scientists think that the interior contains a large core made mostly of melted iron. Mercurys core takes up about 42% of the planets volume. Mercurys highly cratered surface is evidence that Mercury is not geologically active. Named after the Roman goddess of love, Venus is the only planet named after a female. Venus is sometimes called Earths sister planet. But just how similar is Venus to Earth? Venus is our nearest neighbor. Venus is most like Earth in size. Viewed through a telescope, Venus looks smooth and featureless. The planet is covered by a thick layer of clouds. You can see the clouds in pictures of Venus, such as Figure 25.11. We make maps of the surface using radar, because the thick clouds wont allow us to take photographs of the surface of Venus. Figure 25.12 shows the topographical features of Venus. The image was produced by the Magellan probe on a flyby. Radar waves sent by the spacecraft reveal mountains, valleys, vast lava plains, and canyons. Like Mercury, Venus does not have a moon. Clouds on Earth are made of water vapor. Venuss clouds are a lot less pleasant. They are made of carbon dioxide, sulfur dioxide and large amounts of corrosive sulfuric acid! The atmosphere of Venus is so thick that the pressure on the surface of Venus is very high. In fact, it is 90 times greater than the pressure at Earths surface! The thick atmosphere causes a strong greenhouse effect. As a result, Venus is the hottest planet. Even though it is farther from the Sun, Venus is much hotter even than Mercury. Temperatures at the surface reach 465C (860F). Thats hot enough to melt lead! Venus has more volcanoes than any other planet. There are between 100,000 and one million volcanoes on Venus! Most of the volcanoes are now inactive. There are also a large number of craters. This means 
 Question: The inner planet with an average surface temperature of 14 C is

A: earth.
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Q: Context: Work is the use of force to move an object. It is directly related to both the force applied to the object and the distance the object moves. Work can be calculated with this equation: Work = Force x Distance. The equation for work can be used to calculate work if force and distance are known. To use the equation, force is expressed in Newtons (N), and distance is expressed in meters (m). For example, assume that Clarissa uses 100 Newtons of force to push the mower and that she pushes it for a total of 200 meters as she cuts the grass in her grandmothers yard. Then, the amount of work Clarissa does is: Work = 100 N 200 m = 20,000 N m Notice that the unit for work in the answer is the Newton meter (N m). This is the SI unit for work, also called the joule (J). One joule equals the amount of work that is done when 1 N of force moves an object over a distance of 1 m. Q: After Clarissa mows her grandmothers lawn, she volunteers to mow a neighbors lawn as well. If she pushes the mower with the same force as before and moves it over a total of 234 meters, how much work does she do mowing the neighbors lawn? A: The work Clarissa does can be calculated as: Work = 100 N 234 m = 23,400 N m, or 23,400 J The work equation given above can be rearranged to find force or distance if the other variables are known: Force = Work Distance Distance = Work Force After Clarissa finishes mowing both lawns, she pushes the lawn mower down the sidewalk to her own house. If she pushes the mower over a distance of 30 meters and does 2700 joules of work, how much force does she use? Substitute the known values into the equation for force: J Force = 2700 30 m = 90 N Q: When Clarissa gets back to her house, she hangs the 200-Newton lawn mower on some hooks in the garage (see the Figure 1.1). To lift the mower, she does 400 joules of work. How far does she lift the mower to hang it? A: Substitute the known values into the equation for distance: 
 Question: you can calculate distance from work and force with the equation

A:
distance = work/force.
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