In this task, you are given a sentence in the Spanish language. Your task is to translate the Spanish sentence into the English language.

[Q]: Con respecto a la actividad farmacológica de la artemisinina (lactona sesquiterpénica) extraída de la Artemisia annua
[A]: With respect to the pharmacological activity of artemisinin (sesquiterpene lactone) extracted from Artemisia annua


[Q]: La rigidez afectiva se caracteriza por
[A]: Affective rigidity is characterized by


[Q]: ¿Cuál de las siguientes es hoy día la única contraindicación para el tratamiento quirúrgico conservador en el cáncer de mama?
[A]:
Which of the following is currently the only contraindication for conservative surgical treatment in breast cancer?