Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

[EX Q]: Paragraph: The company said the trial will continue unchanged as per the recommendation of a data monitoring committee. The trial was testing Bristol-Myers’ drugs Opdivo and Yervoy, against Opdivo alone, in patients with advanced melanoma. The combination failed to show a statistically significant benefit in patients whose tumors had 1% or lower levels of the PD-L1 protein being targeted, the company said. The American Cancer Society estimates that about 96,480 melanoma cases will be diagnosed in the United States this year. Bristol-Myers shares were trading at $55.99 before the bell. Claim: Bristol-Myers misses main goal of late-stage skin cancer trial.
[EX A]: Bristol-Myers Squibb Co said on Wednesday a late-stage trial testing a combination of its cancer drugs missed a main goal of preventing skin cancer from recurring in a certain group of patients, sending its shares down nearly 1%.

[EX Q]: Paragraph: "The sight of the moon’s shadow passing directly in front of the sun, blotting out all but the halo-like solar corona, may draw the largest live audience for a celestial event in human history. When those watching via broadcast and online media are factored into the mix, the spectacle will likely smash records. “It will certainly be the most observed total eclipse in history,” astronomer Rick Fienberg of the American Astronomical Society (AAS) said last week. The eclipse begins its cross-country trajectory over the Pacific Coast of Oregon in late morning. It will reach South Carolina’s Atlantic shore some 90 minutes later. The total eclipse of the sun is considered one of the most spell-binding phenomena in nature but it rarely occurs over a wide swath of land, let alone one of the world’s most heavily populated countries at the height of summer. In terms of audience potential, it is hard to top the United States, with its mobile and affluent population, even though the direct path is mostly over rural areas, towns and small cities. The largest is Nashville, Tennessee, a city of 660,000 residents. Even so the advent of social media and inexpensive high-tech optics have boosted public awareness, assuring what many U.S. experts predict will be unprecedented viewership for the so-called “Great American Eclipse.”   Some might take issue with that prediction, citing a solar eclipse visible over parts of India, Nepal, Bangladesh and central China in July 2009. National Geographic estimated 30 million people in Shanghai and Hangzhou alone were in its path that day. On Monday, the deepest part of the shadow, or umbra, cast by the moon will fall over a 70-mile-wide (113-km-wide), 2,500-mile-long (4,000-km-long) ""path of totality"" traversing 14 states. The 12 million people who live there can view the eclipse at its fullest merely by walking outside and looking up, weather permitting. (tmsnrt.rs/2fNQHFb)  LIVESTREAMING AND PRICE-GOUGING  Some 200 million Americans reside within a day’s drive of the totality zone, and as many as 7 million, experts say, are expected to converge on towns and campgrounds along the narrow corridor for the event. Many are attending multiday festivals featuring music, yoga and astronomy lectures. Millions more could potentially watch in real time as the eclipse is captured by video cameras mounted on 50 high-altitude balloons and streamed online in a joint project between NASA and Montana State University. A partial eclipse will appear throughout North America. Adding further to the excitement is the wide availability of affordable solar-safe sunglasses produced by the millions and selling so fast that suppliers were running out of stock. The owner of one leading manufacturer reported price gouging by second-hand dealers who were buying up large supplies and reselling them over the internet at a huge mark-up. Not all the hoopla will unfold on dry land. Welsh pop singer Bonnie Tyler is slated to perform her 1983s hit single “Total Eclipse of the Heart” aboard a cruise liner as the vessel sails into the path of totality from Florida on Monday. Back on the ground, forest rangers, police and city managers in the total eclipse zone are bracing for a crush of travelers they fear will cause epic traffic jams and heighten wildfire hazards. “Imagine 20 Woodstock festivals occurring simultaneously across the nation,” Michael Zeiler, an AAS advisory panel member wrote on his website, GreatAmericanEclipse.com, referring to the famously chaotic 1969 outdoor rock extravaganza in upstate New York. Hundreds of residents in a prime-viewing area in Oregon had to evacuate on Saturday under threat from a wildfire raging in the Deschutes National Forest, according to InciWeb fire-tracking website. The so-called Milli Fire, which has scorched more than 7,8OO acres (3,162 hectare), is one of seven burning in Oregon, Montana and Idaho, three of the states crossed by the totality path. Zeiler, an avowed “eclipse chaser” who made the 650-mile (1,046-km) drive from his New Mexico home to Wyoming for a choice view, said South Carolina is likely to see the greatest influx as the destination state closest to the entire U.S. Eastern seaboard. Monday’s event will be the first total solar eclipse spanning the entire continental United States since 1918 and the first visible anywhere in the Lower 48 states in 38 years. The next one over North America is due in just seven years, in April 2024." Claim: Millions of Americans to gaze upon Monday's once-in-a-lifetime eclipse.
[EX A]: Twilight will fall at midday on Monday, stars will glimmer and birds will roost in an eerie stillness as millions of Americans and visitors witness the first total solar eclipse to traverse the United States from coast to coast in 99 years.

[EX Q]: Paragraph: The Texas woman’s name is Cathy Flanders and she has been on a crusade to bring the problem of indoor pollution from candles to the forefront. She has filed a lawsuit against the store that sold her candles which she says resulted in toxic levels of lead in her home and with serious medical consequences on her family. Regardless of the merits of her case, it is true that indoor pollution from certain kinds of candles is becoming a focus of research and is one of the hot topics right now among professionals concerned with health issues in the home. Not all the researchers are focused on lead and there are some who say they feel the danger from lead is reduced by the fact that U.S. candle makers have not used lead in candles for more than 25 years. There is increased focus on what researchers say is a significant contribution of candles to soot residue in buildings, more than has previously been realized, and to what extent that soot can contribute to health problems. While that is being studied, pollution experts recommend choosing candles from U.S. manufacturers that are made of hard wax, have low aromatic properties, burn with a low, even flame and with wicks that burn down evenly with the rest of the candle. They also recommend keeping burning candles out of drafts and not allowing an extinguished candle to continue emitting smoke. For more information: CNN Article about Cathy Flanders Article about Black Soot in the Home from the Environmental Illness Society of Canada  Comments Claim:  An email is making the rounds that talks about a woman in Texas whose family has experienced a variety of health problems which she says are due to the lead content of some candles.  The email warns that burning candles in the home can lead to health problems.      
[EX A]:
Beware of potential pollution from certain candles