TASK DEFINITION: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
PROBLEM: We report a case of acne fulminans occurring during treatment with 13-cis-retinoic acid for cystic acne.

SOLUTION: adverse drug event

PROBLEM: Progressive anemia following combination therapy with interferon-alpha and interleukin-2 in a patient with metastatic renal cell carcinoma.

SOLUTION: adverse drug event

PROBLEM: When the disease recurred conventional amphotericin B was used again, but had to be stopped because of severe side effects.

SOLUTION:
adverse drug event