Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Q: Question: Are perioperative nonselective non-steroidal anti-inflammatory drugs associated with anastomotic leakage after colorectal surgery?
Answer: There does not appear to be a significant association between perioperative ketorolac use and anastomotic leakage after colorectal surgery. However, further prospective studies are needed to confirm our findings before definitive guidelines on NSAID use perioperatively can be recommended.

A: no
****
Q: Question: Do a Profilometric Study to Assess the Role of Toothbrush and Toothpaste in Abrasion Process?
Answer: Besides supporting the fact that toothpaste is needed to create a significant abrasion, this study also showed that a softer toothbrush can cause more abrasion than harder ones. The flexibility of bristles is only secondary to abrasion process and abrasivity of dentifrice has an important role in abrasion process.

A: yes
****
Q: Question: Does inactivation of patched1 in murine chondrocytes cause spinal fusion without inflammation?
Answer: Our findings indicate that chronic activation of the HH signal pathway in spinal chondrocytes can trigger an ankylosing spine morphology without immune cell contributions. Hence, the destruction of cartilage and loss of axial joint integrity can result from chondrocyte-intrinsic defects of monogenic origin.

A:
yes
****