Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Input: Consider Input: Paragraph: "The story covers cost in the very last two lines. Adequate quantification of benefits seen in the study. Story says ""few eye-related complications"" were reported in the Lucentis group, but didn’t say what few means or what they were. We don’t think that’s quite adequate. Adequate job explaining how the study was done and what it means. No disease mongering in the story. One quote from the head of the National Eye Institute. But he didn’t really evaluate evidence – only talked about hope. Meantime, no mention that Genentech funded  the trial (a strength of the NYT story was its discussion of the ""pay for play"" aspect of the research) – and no mention that Dr. Bressler disclosed financial ties to Genentech. From the Times: Some doctors criticized the organizers of the trial for testing Lucentis rather than another Genentech drug, Avastin, which works in the same way as Lucentis. Although it is a cancer drug, Avastin is often used off-label for eye diseases because it is far cheaper than Lucentis, costing only $20 to $100 a dose, compared with $2,000 for Lucentis. Avastin is undercutting sales of Lucentis, which totaled $1.1 billion in the United States last year. Organizers of the trial conceded that a major reason Lucentis was chosen was that Genentech, which is now owned by Roche, agreed to provide the drug free of charge and to contribute $9 million in additional financing — but only if Lucentis were used. “Obviously you can’t underplay $9 million,” said Dr. Ferris of the eye institute, which is part of the part of the National Institutes of Health. But he said there were other factors as well, like a belief that Lucentis might have been the better drug. Dr. Philip J. Rosenfeld, a professor of ophthalmology at the University of Miami, said the decision was “clearly a case of pay to play” since Genentech’s money dictated the choice of drugs. At least the story mentioned the uncertainty about whether Lucentis is any better  than the cheaper Avastin, and mentioned an upcoming trial comparing the two in age-related macular degeneration. The story explains that Lucentis was approved 4 years ago for another cause. Story explains the drug is already approved for another use, and it also – at the very end – mentions that an older and much cheaper drug is also effective. It’s clear the story did not rely on a news release." Claim: Drug Reverses Diabetes-Related Vision Loss

Output: The key difference between this and the NYT story was that WebMD didn’t reflect on the question of why Genentech didn’t test its cheaper Avastin against the much more expensive Lucentis. The important issue of corporate sponsorship of a clinical trial was overlooked. You want to talk about comparative effectiveness research? This would have been a good place for it.


Input: Consider Input: Paragraph: Britain’s legal bookmakers reported high interest Tuesday in the names Alexander, James and Arthur. They also noted speculation about the name Spencer, the maiden name of Harry’s late mother, Princess Diana. Royal babies usually have a string of names, opening the way for endless betting possibilities. “Following a flurry of bets last evening, Alexander is now the new favorite at the top of our name betting and the one we are fearing the most,” said John Hill of the Coral betting agency. Alexander has 4/1 odds at Coral, while Arthur is 6/1 and Albert, James and Spencer are all 8/1. Choosing Spencer as a first or middle name is seen as a way for Harry to honor Diana, who died in a Paris car crash in 1997 when he was only 12. Before he married Meghan last year, Harry spoke about his desire to pay tribute to his mother’s memory during the wedding ceremony. Others believe Meghan could choose a name that reflects her American biracial heritage. One Twitter user suggested Marvin — for the late singer Marvin Gaye. The infant, known only as Baby Sussex for the moment, was born Monday at 5:26 a.m. at a yet-undisclosed location. In a gushing announcement of the birth, Harry said he and Meghan are “thinking” about names and hinted that an announcement might be made Wednesday or shortly thereafter. The couple is also expected to pose with their newborn or release a photo on their Instagram account at some time and to publicly name godparents for the child. The new arrival is the eighth great-grandchild of Queen Elizabeth II, who smiled when asked about the baby’s arrival at a luncheon Tuesday. Asked if life is good, the 93-year-old monarch said: “Yes, thank you.” The baby boy is the first of her great-grandchildren to have an American parent. His mother Meghan is the daughter of a white man and a black woman, bringing a biracial heritage to the House of Windsor. Trevor Phillips, a retired black broadcaster who headed Britain’s Equality and Human Rights Commission, wrote an open letter to the royal baby, saying his arrival reflects British society’s more open attitude nowadays and the increasing inclusiveness of the royal family. “This is a family that lives the reality of a multicultural world daily,” he said. “It’s their job: to interact with people of different backgrounds to themselves on behalf of the nation, and to treat them all with respect. I have to tell you, they are pretty good at it.” He went on to tell the baby: “Whether you like it or not, you’re going to have a special place in the nation’s heart.” Prince William, Harry’s older brother, joked Tuesday that he will be glad “to welcome my own brother into the sleep deprivation society that is parenting!” “Obviously thrilled, absolutely thrilled, and obviously looking forward to seeing them in the next few days when things have quietened down,” William told reporters. The birth produced a moment of high drama likely to be replayed for the rest of Harry’s life. The prince, who has battled mental health challenges since the abrupt loss of his mother at a young age, emerged with the world’s most satisfied grin Monday afternoon to announce the birth of his son before TV news cameras. “We’re both absolutely thrilled and so grateful for all the love and support from everybody out there. It’s been amazing, so we just wanted to share this with everybody,” the normally press-shy royal gushed. Harry also burnished his feminist credentials — and paid tribute to mothers around the world — after witnessing the birth. “It’s been the most amazing experience I could ever have possibly imagined,” he said. “How any woman does what they do is beyond comprehension.” ___ Read all Associated Press coverage of the latest royal baby at https://www.apnews.com/RoyalBaby Claim: Will new royal baby’s name honor Princess Diana? Stay tuned.

Output: Britons love to lay down their bets — and with the birth of a healthy baby boy for Meghan, the Duchess of Sussex, and Prince Harry, it’s time to focus on boys’ names.


Input: Consider Input: Paragraph: Instead of sticking to his original 250,000-pound ($365,000) scheme of picking his perfect wife from the glamorous candidates he had flown to the island, Downes, 50, found himself in the grip of a manic episode, proclaiming himself not only the creator of mankind but the creator of God. That definitely was not in the script. Downes had asked a cameraman to document his unusual plan to find a soulmate. Instead, it was his mania that was caught on film, giving a rare insight into bipolar disorder. “I wanted to find a bride but when I go manic, I become Ya, the creator of Allah and the creator of God and I start thinking of an awful lot of things other than beautiful ladies that are there,” Downes told Reuters in London after the screening of the documentary created out of his 2009 trip to Jamaica. “True Stories: Bipolar Expedition,” by film maker Mark James, aired on British television this week and will become available internationally. “When I went to Jamaica, Paul was in the grip of a developing mania which I obviously hadn’t witnessed before and had no idea what that was, so I filmed all the events as you see in the film,” James told Reuters. “He just got more interested in me and the camera and making speeches which went on every day.”   MODERN-DAY DISEASE   Before being diagnosed with bipolar at the age of 44, Downes was living a high-powered life of luxury, making business deals, playing golf and gambling. But one day, while holidaying in Jamaica, he began acting strangely. He started smoking pot, stopped sleeping, asked a stranger to marry him and eventually jumped off a cliff into the sea without knowing how to swim. “I don’t know what triggered that because if anybody had said that I could possibly have a mental illness in the first 44 years of my life, I’d have said you were the crazy person,” Downes said. Known as the “disease of the 21st century,” bipolar disorder has made headlines with celebrities such as Stephen Fry, Richard Dreyfuss and Sinead O’Connor openly discussing their struggles. It causes mood swings from severe depression to dramatic highs, which can range from a couple times a year, to a couple times a day, depending on the severity of the disorder in the individual, and is often followed by suicidal feelings. “In my last manic episode, I had seven chauffeur-driven Rolls-Royces with a private detective visit Prince Charles, Stephen Hawkins and Simon Cowell with DVDs of taped speeches and certain gifts,” Downes said. In the documentary, James suggests that Downes’ first ever manic episode in 2004 was triggered by a business deal gone wrong. Downes strongly denies this, saying he has no idea what sparked it off. There is a lot that is not understood about the condition and the biggest problem medical experts face is actually diagnosing it. “It’s like trying to unravel the origins of the universe,” said James. “We’ve only just really started to scratch the surface of what the whole universe is about and I think it’s the same with the human mind.”   Many studies have shown there is a definite link between bipolar disorder and creative genius. Although Downes is no artist, his wealth allows him to create other worlds — such as the Jamaica wife hunt — that have cost him around 1 million pounds in the past six years. James said the documentary illustrates how multi-faceted the human mind is. “It is a manic episode, but it’s sort of living out something which is so extraordinary and colorful,” he added. “In a way it’s like making a work of art.”   The manic episode on the island didn’t entirely derail Downes’ original quest however — he plans to travel to Ukraine in July to meet two of the women, one of whom he hopes will become his wife. Claim: Film captures mood swings of bipolar disorder.


Output: After spending two weeks on a sun-drenched island off Jamaica with 12 Ukrainian beauties, British multi-millionaire Paul Downes went off the rails.