Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: High-resolution CT (HRCT) findings of this disease were compared with the pathology.
Example Output: non-adverse drug event

Example Input: We describe 2 male patients, a 49-year-old with psoriatic arthritis and impaired renal function and a 43-year-old renal transplant recipient, who both sustained a marked decline in glomerular filtration rate in conjunction with a selective inhibitor of cyclooxygenase-2 (COX-2), rofecoxib.
Example Output: adverse drug event

Example Input: Because of its selective action on B lymphocytes, it is considered a moderate immunosuppressant in terms of infection.
Example Output:
non-adverse drug event