Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Does progression rates and sample size estimate for PPMS based on the CLIMB study population?
Answer: Our modern PPMS cohort is demographically similar to previously studied cohorts. PPMS is associated with faster disability accrual than ROMS. Current real-world observations of time to sustained progression will inform design of new clinical trials for PPMS.

Answer: yes


Question: Question: Do increased homocysteine levels exist in women with preeclampsia from early pregnancy?
Answer: Our results indicate that higher homocysteine levels exist in women with PE from early pregnancy and continue till delivery.

Answer: yes


Question: Question: Does intestinal epithelial vitamin D receptor deletion lead to defective autophagy in colitis?
Answer: Our study demonstrates fundamental relationship between VDR, autophagy and gut microbial assemblage that is essential for maintaining intestinal homeostasis, but also in contributing to the pathophysiology of IBD. These insights can be leveraged to define therapeutic targets for restoring VDR expression and function.

Answer:
yes