Given scientific fact as input, generate the question from this fact such that it can be answered from the input.
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Question: Sexually do invertebrates reproduce.

Answer: How do invertebrates reproduce?


Question: The mesopause is at the top of the mesosphere.

Answer: What is at the top of the mesosphere?


Question: Backbone distinguishing feature predates the branching of mammals from other vertebrates.

Answer:
What distinguishing feature predates the branching of mammals from other vertebrates?