Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
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Question: Sir Thomas Lea, 1st Baronet (17 January 1841 -- 9 January 1902) was an English carpet manufacturer from Kidderminster, and a Liberal Party politician.

Answer: What nationality is Sir Thomas Lea, 1st Baronet?


Question: 1. In order to investigate the biological function of the human CLN3 gene that is defective in Batten disease, we created a yeast strain by PCR-targeted disruption of the yeast gene (YHC3), which is a homologue of the human CLN3 gene. 2. The phenotypic characterization revealed that the yhc3 delta mutants are more sensitive to combined heat and alkaline stress than the wild-type strains as determined by inhibition of cell proliferation. 3. This suggests that the yhc3 delta mutant is a good model to investigate the biological function of human CLN3 gene in mammalian cells and to understand the pathophysiology of juvenile Batten disease.

Answer: What is the effect of a defective CLN3 gene?


Question: It was built in 1923 with a 10,000-person capacity (seated and standing) to be the home arena of the NHL's Ottawa Senators by the Ottawa Auditorium Limited, a consortium controlled by T. Franklin Ahearn and Senators' owners Edgar Dey and Tommy Gorman.

Answer:
What team uses Ottawa Auditorium?