TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Is transgene-induced gene silencing affected by a change in ploidy level?
Answer: Our results in A. thaliana indicated that there is no effect of ploidy level on transgene-induced post-transcriptional gene silencing. Our findings that post-transcriptional mechanisms were equally effective in diploids and tetraploids supports the use of transgene-driven post-transcriptional gene silencing as a useful mechanism to modify gene expression in polyploid species.

SOLUTION: no

PROBLEM: Question: Is muscle dysfunction during exercise of a single skeletal muscle in rats with congestive heart failure associated with reduced muscle blood supply?
Answer: The cause of contractile dysfunction in a single exercising skeletal muscle in rats with CHF cannot be explained simply by reduced blood supply. In addition, absence of changes in high-energy phosphates and metabolites indicate that the oxidative metabolism of SOL is intact in rats with CHF.

SOLUTION: no

PROBLEM: Question: Does next-generation sequencing of adrenocortical carcinoma reveal new routes to targeted therapies?
Answer: Next-generation sequencing can discover targets of therapy for relapsed and metastatic ACC and shows promise to improve outcomes for this aggressive form of cancer.

SOLUTION:
yes