instruction:
Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.
question:
A much e-mailed piece about pink-clad prisoners of the Maricopa County Jail was extracted from a July 2003 Associated Press offering about the Summer 2003 heat wave’s effect on the Phoenix area. Those few paragraphs devoted to describing the condition of the inmates held in that jail went on to be widely circulated on the Internet although they formed only the smallest portion of the original piece, an article that described the air’s heat creating turbulence for airplanes overhead, car windshields shattering or falling out, dogs burning their paws on the pavement, and candles melting indoors:  It’s even hotter than usual in Phoenix, the Associated Press reports: About 2,000 inmates living in a barbed-wire-surrounded tent encampment at the Maricopa County Jail have been given permission to strip down to their government-issued pink boxer shorts. On Wednesday, hundreds of men wearing boxers were either curled up on their bunk beds or chatted in the tents, which reached 138 degrees inside the week before. Many were also swathed in wet, pink towels as sweat collected on their chests and dripped down to their pink socks. “It feels like you are in a furnace,” said James Zanzo’t, an inmate who has lived in the tents for 1 1/2 years. “It’s inhumane.” Joe Arpaio, the tough-guy sheriff who created the tent city and long ago started making his prisoners wear pink, is not sympathetic. He said Wednesday that he told the inmates: “It’s 120 degrees in Iraq and the soldiers are living in tents and they didn’t commit any crimes, so shut your mouths. ” KIND OF PUTS THINGS IN PERSPECTIVE DOESN’T IT? A clue as to the ‘why’ of the selective quoting is contained in the tagline now often part of the forwards: “Kind of puts things in perspective doesn’t it?” Someone was struck by the comparison of the kvetching prisoners to the (presumed uncomplaining) troops serving in Iraq, and was moved to excerpt only that portion of the article to share with others. That the forward has proved as popular as it has shows the comparison resonates with a great many. The U.S. soldiers serving in Iraq may well be bona fide tough-as-nails servicemen, but at least in our mental image of them we also need them to be larger than life. We like to think of them as lantern-jawed heroes coolly dealing with the impossible situation that is Iraq without giving so much as a thought to their personal safety or even letting as little as a complaining word fall from their lips about the miserable conditions they must endure during that tour of duty. The juxtaposition of these brave soldiers to the societal dregs that wash up into a county jail is thus eminently satisfying to contemplate — it’s the comparison of giants to ants, working to exalt the one even as it makes the other look petty and small. Yet if the prisoners housed in Arizona’s Maricopa County tent city jails were complaining, they had some good reasons. At that facility the incarcerated were fed only two meals a day, with green bologna sometimes appearing on the menu. They were quartered in outdoor tents under sweltering conditions, and they slept on cots which lack pillows. They worked on chain gangs. And they wore pink underwear. Former Maricopa County Sheriff Joe Arpaio, of the “It’s 120 degrees in Iraq and the soldiers are living in tents and they didn’t commit any crimes, so shut your mouths” quote, reveled in the sobriquet ‘America’s Toughest Sheriff.’ He enjoyed a very high voter approval rating for a time and had little trouble being re-elected to his post multiple times. He was a controversial figure, vilified by some and worshipped by others. In June 2004 the e-mailed excerpt from the July 2003 Associated Press article circulated anew on the Internet, this time prefaced as follows:  This is the way he is, and he has been re-elected several times … Sheriff Joe Arpaio (in Arizona) is doing it RIGHT!! : He has jail meals down to 40 cents a serving and charges the inmates for them. He stopped smoking and porno magazines in the jails. Took away their weights. Cut off all but “G” movies. He started chain gangs so the inmates could do free work on county and city projects. Then he started chain gangs for women so he wouldn’t get sued for discrimination. He took away cable TV until he found out there was a federal court order that required cable TV for jails. So he hooked up the cable TV again but only let in the Disney channel and the weather channel. When asked why the weather channel he replied, so they will know how hot it’s gonna be while they are working on my chain gangs. He cut off coffee since it has zero nutritional value. When the inmates complained, he told them…. this is a good one……”This isn’t the Ritz/Carlton. If you don’t like it, don’t come back.” He bought Newt Gingrich’ lecture series on videotape that he pipes into the jails. When asked by a reporter if he had any lecture series by a Democrat, he replied that a democratic lecture series might explain why a lot of the inmates were in his jails in the first place. You have to love this guy!! More on the AZ Sheriff … [at this point, the text quoted above was repeated]  With one exception (which could simply amount to no more than our not having yet found the right supporting articles), the claims made in the 2004 preface checked out. Sheriff Joe Arpaio did ban  smoking, coffee, pornographic magazines, movies, and unrestricted television in all his jails. Those incarcerated in his tent city jail did indeed work on chain gangs, pull weeds for the city and county, clear brush, and the like. In 1996 the Sheriff put the nation’s first female chain gang to work. Although the e-mailed account made it sound as if he did so out of fear of prosecution for discrimination, there was no such threat lurking in the background — he chose that course of action because it suited his beliefs: “I don’t believe in discrimination in my jail system. Crime knows no gender and neither should punishment,” he said. Regarding the claim about his airing a Newt Gingrich lecture series on the jail’s television system, in 1995 the controversial lawman used canteen funds to buy the Republican House speaker’s 10-part, $150 video lecture series with the intent of piping it into the inmates’ cells. When asked if he’d also be providing those in his charge with a lecture series done by a Democrat, he replied in the negative. “For one thing I don’t know of any,” he said. “And some people might say these guys already got enough of those ideas.” He was also proud of having lowered the cost of feeding inmates in his care. Though assorted news articles quoted slightly differing figures, a 40¢ per serving expenditure was the one most often touted. “It costs more to feed our police dogs than our inmates. The dogs never committed a crime, and they’re working for a living,” Arpaio said. In 1998 Arpaio instituted a policy of charging inmates for their meals, levying a dollar-a-day tariff against each of those incarcerated. In 1994 he banned coffee from the Maricopa County Jail, but he did so not because of its lack of nutritional value, but to protect inmates and guards from hot-coffee assaults by other inmates and to lower costs. (By eliminating the estimated 5,000 cups of coffee served daily for 5,400 inmates, it was expected the county would save $94,158 a year.) The one item we have yet to validate is the assertion that Arpaio deprived inmates of cable TV until discovery that such act was in violation of a federal court order. We’ve yet to locate this order or to confirm that television programming was ever denied those in his care. It is on record, however, that inmates in his charge view only selected programming, such as what’s on The Weather Channel. (“I think my chain gang deserves to know how hot it is when they hit the streets,” said Arpaio.) In September 2007 the following e-mail forwards about Sheriff Arpaio began to circulate:   Sheriff Joe is at it again. Maricopa County was spending approx. $18 million dollars a year on stray animals, like cats and dogs. Sheriff Joe offered to take the department over, and the County Supervisors said “Okay.” The animal shelters are now all staffed and operated by prisoners. They feed and care for the strays. Every animal in his care is taken out and walked twice daily. He now has prisoners who are experts in animal nutrition and behavior. They give great classes for anyone who’d like to adopt an animal. He has literally taken stray dogs off the street, given them to the care of prisoners, and had them placed in dog shows. The best part? His budget for the entire department is now under $3 million. Now he’s in trouble with the ACLU again. He painted all his buses and vehicles with a mural that has a special hotline phone number painted on it, where you can call and report suspected illegal aliens. Immigrations and Customs Enforcement wasn’t doing enough in his eyes, so he had 40 deputies trained specifically for enforcing immigration laws, started up his hotline, and bought 4 new buses just for hauling folks back to the border. Although Sheriff Joe Arpaio did not (as implied above) take over the operations of the entire Maricopa County Animal Care & Control (MCACC) department, he was instrumental in the opening of the Maricopa Animal Safe Hospice (MASH), a no-kill animal shelter operated by the Maricopa County Sheriff’s Office (MCSO) in what was formerly Phoenix’s First Avenue Jail. The MASH is a facility dedicated to caring for rescued animals that have been abused or neglected (as well as temporarily caring for the pets of owners who have checked into domestic violence shelters):  Sheriff Joe Arpaio’s no-kill animal shelter, MASH, was created to house and care for animals that have been abused or neglected by their caretakers and rescued by the Animal Cruelty Investigative Unit. The purpose of the shelter is to provide a safe, healthy and healing shelter for these tragic animals, who must necessarily await the outcome of their owners’ cruelty cases in court. Hopefully, their ultimate outcome will be adoption into loving, permanent homes. The first shelter opened by Sheriff Arpaio is in the First Avenue Jail, located at First Avenue and Madison Street, Phoenix, Arizona. This 30-year-old jail previously held inmates, but was closed for repairs to plumbing in December 1999. Though no longer suitable for housing inmates, the jail looks like paradise to the four-footed victims now housed and recovering there. The MASH location in the First Avenue Jail is air-conditioned, and the cells have been reconditioned to comfortably house animals. In July 2007 Sheriff Arpaio launched a hot line for calling in tips and information about people living and working in Maricopa County illegally. Then in September 2007 he unveiled “moving billboards” in the form of four trucks and eight inmate passenger vans plastered with the hot line number and signs reading “Do Not Illegally Enter” and “Help Sheriff Joe Arpaio Fight Illegal Immigration and Trafficking.”  Critics contend that this move constitutes racial profiling; Sheriff Arpaio maintains that his signs say nothing about ethnic backgrounds: “It says illegal immigration and trafficking. I don’t care where they’re from.” Sheriff Arpaio finally stepped down after losing a re-election bid to Democrat Paul Penzone in 2016.
answer:
An Arizona sheriff dismissed prisoners' bellyaching about the heat by pointing out that soldiers serving in Iraq cope with similar conditions.


question:
Developed by Eli Lilly and Co’s (LLY.N) Loxo Oncology and marketed by German drugmaker Bayer (BAYGn.DE), it fights a rare genetic mutation that appears in less than 1% of solid tumors, regardless of where they appear in the body. Finding those patients will require widespread adoption of sophisticated tests that look for multiple genetic alterations that could be driving the cancer. So far, progress has been slow. Adoption of so-called next-generation sequencing (NGS) tests has been stalled by lack of reimbursement from insurers over concerns that the evidence is not there yet to support widescale use, according to more than a dozen interviews with oncologists and pharmaceutical and diagnostic industry executives. As a result, pharma companies from small biotech Blueprint Medicines Corp (BPMC.O) to larger rivals Lilly and Roche Holding AG (ROG.S) are taking matters into their own hands, bulking up staff to increase patient and physician awareness about testing and building up a gene testing infrastructure that for many community hospitals still does not exist. Bayer executives told Reuters it plans to spend $70 million to increase patient and physician awareness of testing for rare mutations and to encourage regulatory approval of more tests. They expect that budget to expand as Vitrakvi continues to win approval in other countries. Lilly told Reuters the company has signed an agreement with Thermo Fisher Scientific (TMO.N) to develop a companion diagnostic test for its experimental drug, LOXO-292. The deal adds RET mutations - the target of both Lilly’s and Blueprint’s drugs - to Thermo’s Oncomine Dx Target Test, which local pathology labs can use to identify multiple genes linked with non-small cell lung cancer. The agreement is aimed to help identify more lung and thyroid cancer patients who may benefit from the Lilly or Blueprint therapies. The Thermo test is already approved by the U.S. Food and Drug Administration - a key standard for Medicare coverage, the companies said. According to Dr. Brian Alexander, chief medical officer of Roche’s gene testing company Foundation Medicine, only about 15% of U.S. patients with advanced cancers get comprehensive genomic  profiling. Another 25% get single-gene testing, he said, and a large proportion “are not getting any testing at all.”  At MD Anderson, which sees 100,000 new cancer patients a year, only around 10,000 eventually have their tumors sequenced. For a rare few, the tests are lifesaving. Xin Zheng, 47, a mother of three in Michigan who was referred to Reuters by Blueprint, was diagnosed with stage 4 lung cancer in 2016. After failing several treatments, she was out of options. Her husband, Zhigang Wei, asked for genetic sequencing, and the test turned up a RET mutation. After contacting multiple lung cancer experts, Zhigang found an early-stage clinical trial treating patients with Blueprint’s experimental drug, BLU-677. Now, Xin is nearly back to normal. “My wife is lucky,” he said, adding her quality of life is much better and she has hope for the future. Finding patients with such rare mutations is like “looking for the needle in the haystack,” said Stefan Oelrich, head of pharmaceuticals at Bayer. Dr. David Hyman of Memorial Sloan Kettering Cancer Center, who tested Vitrakvi in clinical trials, said making these tests the norm for advanced cancer patients will require a huge shift in the way oncology is practiced. “It’s painful to know there are patients out there with these alterations who are dying without knowing about it and without getting any treatments,” he said. For Bayer’s Vitrakvi and Roche’s Rozlytrek, along with similar drugs in development, genomic testing is critical to finding patients who can benefit from them. Cancer patients and drug companies alike got a boost last year when the federal Medicare health program for the elderly and disabled said it would cover FDA-approved tests for advanced cancer patients that can identify hundreds of genetic mutations at once. A Medicare endorsement is generally followed by widespread coverage decisions by private insurers. But the final regulations dropped a requirement that testmakers prove the tests are cost-effective and improve patient care. That created an “evidence gap” that has allowed some insurers, also known as third-party payers, to withhold coverage or demand more proof that they benefit patients, said Jeff Schreier of Diaceutics PLC (DXRX.L), a data analytics company that works with drugmakers to improve diagnostic testing. “More payers are coming around, but it’s slow,” he said. The most recent coverage policy from CVS Health Corp’s (CVS.N) Aetna approves many single-gene tests for specific cancers, but still largely considers multi-gene tests experimental. Anthem Inc’s (ANTM.N) policy limits testing to “medically necessary” use and states there’s “insufficient published evidence” to support widespread testing. And while Foundation Medicine’s and Thermo Fisher’s tests are getting reimbursed from Medicare, many hospitals such as MD Anderson, which have developed their own tests, are not guaranteed payment. “Reimbursement is still a driving force,” MD Anderson’s Kenna Shaw said of genomic testing, which costs an average of $5,000 per patient globally. Lilly bought Loxo in January for $8 billion to profit from its targeted drugs in early-stage development. Bayer secured the rights to Loxo’s two leading compounds in a 2017 alliance. Dr. Anthony Sireci, Loxo’s senior medical director, said the company has been working to “democratize” testing in the United States by increasing its use in local pathology labs, where most cancer testing has traditionally been done. The Thermo Fisher agreement will support those goals and expand patients’ access to “high-quality genomic testing,” he said. Bayer has hired diagnostic experts to help its medical and sales staff assess the barriers to genomic testing and ensure that local pathology labs are including the genetic alterations targeted by its drugs when they profile tumors, the company’s oncology strategic business chief Robert LaCaze said in an interview. Bayer also launched a public awareness campaign called “Test Your Cancer” that urges patients to ask their doctors about genomic cancer testing. The company is working with testing providers to ensure test reports are easy to understand. Blueprint, which has six genomically-targeted drugs in development, told Reuters it plans to hire six diagnostics experts to increase awareness of the mutations their drugs target, especially in community medical practices, where 70% of cancers are treated. Bayer sees signs of progress. Based on internal data, the company estimates average sequencing rates across tumors neared 30% last year, and the company saw a two-fold increase in the number of labs offering tests that carry the mutation targeted by Vitrakvi. Bayer has not released sales figures for Vitrakvi. Asked for an update in the most recent earnings call in July, Bayer’s Oelrich said uptake is going “according to plan,” but declined to say how many patients are using the drug. LaCaze said with very rare cancers like the ones Vitrakvi targets, sales growth is “something that will build over time.”
answer:
Inside drugmakers' strategy to boost cancer medicines with 'Lazarus effect'.


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The Center for Disease Control and Prevention’s National Center for Health Statistics said Thursday that the number of U.S. babies born last year fell 2 percent from 2016 to 3.85 million, also a 30-year low. Births have fallen for three straight years. The fertility rate dropped 3 percent last year to 60.2 births per 1,000 women ages 15 through 44. An aging society has already weighed on economic growth in the United States in the past decade, with the vast baby boom generation retiring and fewer young people replacing them. Thursday’s data suggests that the trend is likely to continue. Economic growth is generally driven by population growth and worker efficiency, both of which have slowed in the past decade in the United States. Kathy Bostjancic, an economist at Oxford Economics, a consulting firm, said that roughly 10 years ago, the number of Americans working or looking for work was growing about 1 percent annually. With birthrates declining, that figure has since fallen to about a 0.3 percent growth rate. That essentially acts as a 0.7 percentage point drag on the United States’ long-run growth. “Demographics have a really powerful impact on the economy,” Bostjancic said. The U.S. economy has grown at a 3 percent average annual rate since World War II. Yet it hasn’t reached that pace for a full calendar year since 2005. The baby boomers first reached retirement age in 2008. The Federal Reserve in March upgraded its short-term economic growth forecast to about 2.7 percent for this year and 2.4 percent in 2019, partly because of the Trump administration’s tax cuts. But the Fed kept its longer-run annual growth forecast at just 1.8 percent, reflecting the demographic headwinds. Aside from fewer workers, an aging society can hold back growth because fewer people are buying homes, cars and other costly purchases. Savings generally rise as people age and prepare for retirement. And as elderly people live longer, they also slow their spending while in retirement, Bostjancic noted. Most economists attribute the low interest rates and low inflation of the past decade, in the United States, Europe and Japan, at least in part to aging. In Japan, where adult diapers outsell those for children, the impact of fewer births has kept growth nearly nonexistent for more than two decades. The economy has picked up recently and enjoyed two straight years of growth, the longest such streak since the late 1980s, before contracting again in the first three months of this year. The U.S. accepts many more immigrants than does Japan, and that influx has boosted population growth. The Labor Department released separate data Thursday showing that last year, there were 27.4 million foreign-born workers in the United States, the most since records began in 2005. Immigrants now make up 17.1 percent of the U.S. workforce. Economic research earlier this year found that U.S. fertility fell sharply roughly nine months before the past three recessions. That suggests that such declines could signal economic downturns. But Kasey Buckles, an economics professor at Notre Dame who conducted the research with two colleagues, said that recent such declines aren’t sharp enough to point to a recession. Instead, she noted that fertility declines over the past three years have occurred mostly among women under 30. Birth rates among older women have risen or held steady. That suggests that the fertility declines largely reflect a drop in unwanted pregnancies since the 2008-2009 recession. Fertility among women of all ages fell sharply in 2008 and 2009, Buckles said, but rebounded quickly for women 30 and over. Separate data from the Guttmacher Institute, a policy organization that tracks reproductive health, shows that unwanted pregnancies have fallen since the Great Recession, Buckles said. “It’s possible that the Great Recession may have been something of a triggering event that caused people to be more intentional about their fertility,” she said. ___ Contact Chris Rugaber on Twitter at http://Twitter.com/ChrisRugaber .
answer:

Lowest US birth rate in 3 decades could pose risk to economy.