In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

Ex Input:
Infection of BALB/c mice with mouse hepatitis virus, strain JHM (MHV-JHM), at any of several intervals relative to ovalbumin (OVA) administration resulted in elevated OVA-specific IgG 2 a titers. Since gamma interferon (IFN) has been implicated as an up-regulator of IgG 2 a production, attempts were made to determine whether levels of this cytokine were modified in sera of infected mice. Serum IFN-y was not detected, but treatment of MHV-JHMinfected mice with monoclonal anti-IFN-? antibody resulted in high mortality with decreased survival times, enhanced virus titers in liver and spleen, and more severe virus-associated pathology, compared to mock-treated, infected mice. Immunotherapy with recombinant IFN-7 ameliorated disease as reflected by mortality rates and virus titers in target organs.

Ex Output:
The role of gamma interferon in infection of susceptible mice with murine coronavirus, MHV-JHM


Ex Input:
Autophagy and autophagy-related processes are fundamentally important in human health and disease. These processes are viewed primarily as cellular degradative pathways that recycle macromolecules and dysfunctional or redundant organelles into amino acids, sugars and lipids, especially during starvation. However, the ubiquitin-like autophagy proteins and other components of the autophagic machinery additionally participate in cellular reprogramming. We highlight these non-autophagic roles of autophagy proteins with the aim of drawing attention to this growing, but unexplored, research topic. We focus on the non-autophagic functions of autophagy proteins in cell survival and apoptosis, modulation of cellular traffic, protein secretion, cell signalling, transcription, translation and membrane reorganization.

Ex Output:
review review Non-autophagic roles of autophagy-related proteins


Ex Input:
Callitrichids, marmosets and tamarins are small Central and South American nonhuman primates. All are considered threatened in the wild and many are on the endangered species list (Convention on International Trade in Endangered Species of Wild Fauna and Flora: Appendix 1). Because of their small size and anthropomorphic appeal, people are interested in owning callitrichids as pets. Hand-raised bottle-fed babies are quite charming until sexual maturity, at which time they often become aggressive and unpredictable to humans, including their owners. Consequently, people should be discouraged from keeping callitrichids as pets. If a veterinarian is consulted about callitrichids by a potential owner before purchase, it may be possible to offer encouragement toward a more suitable pet (e.g., ferret and sugar glider).

Ex Output:

REVIEW HUSBANDRY AND MEDICAL CARE OF CALLITRICHIDS