TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: In 1997 the Kymi Province was merged with the Uusimaa Province and the southern parts of the Hame Province into the new Southern Finland Province.

SOLUTION: What was replaced Kymi Province?

PROBLEM: Early one morning, a taxi pulls up at Tiffany & Co. on Fifth Avenue in New York City, from which elegantly dressed Holly Golightly (Audrey Hepburn) emerges. After looking into the shop's windows, she strolls home. Outside her apartment, she fends off Sid Arbuck (Claude Stroud), her date from the disastrous night before. Later, she is awakened by new neighbor Paul Varjak (George Peppard), ringing her doorbell to get into the building. The pair chat as she dresses to leave for her weekly visit to Sally Tomato (Alan Reed), a mobster incarcerated at Sing Sing prison. Tomato's lawyer, O'Shaughnessy, pays her $100 a week to deliver "the weather report". Audrey Hepburn as Holly Golightly As she is leaving for Sing Sing, Holly is introduced to Paul's "decorator", wealthy older woman Emily Eustace Failenson (Patricia Neal), whom Paul nicknames "2E". That night, Holly goes out onto the fire escape to elude an over-eager date (Mel Blanc). She peeks into Paul's apartment and sees 2E leaving money and kissing Paul goodbye. After 2E leaves, Holly enters Paul's apartment and learns that he is a writer who has not had anything published since a book of vignettes five years before. Holly, in turn, explains that she is trying to save money to support her brother Fred when he gets out of the Army. The pair fall asleep, but are awakened when Holly has a nightmare about Fred. She later buys Paul a typewriter ribbon to apologize and invites him to a party at her apartment. There, Paul meets her Hollywood agent, O. J. Berman (Martin Balsam), who describes Holly's transformation from country girl into Manhattan socialite. He is also introduced to Jose da Silva Pereira (Jose Luis de Vilallonga), a wealthy Brazilian politician, and Rusty Trawler (Stanley Adams), the "ninth richest man in America under 50." In the days that follow, Paul and Holly become closer. One day, 2E enters Paul's apartment, worried that she is being followed. Paul tells her that he will investigate and eventually confronts Doc Golightly (Buddy Ebsen), Holly's estranged husband. Doc explains that Holly's real name is Lula Mae Barnes. They married when she was 13, and he wants to take her back to Texas, as Fred will be returning. After Paul reunites Holly and Doc, she tells Paul the marriage was annulled. At the bus station, she tells Doc she is not going with him. Doc leaves broken-hearted. After drinking at a club, Paul and Holly return to her apartment, where she drunkenly tells him that she plans to marry Trawler for his money. A few days later, Paul learns that one of his short stories will be published. On the way to tell Holly, he sees a newspaper headline stating that Trawler has married someone else. Holly and Paul agree to spend the day together, taking turns doing things that each has never done before. At Tiffany's, Paul has the ring from Doc Golightly's box of Cracker Jack engraved as a present for Holly. After spending the night together, he awakens to find her gone. When 2E arrives, Paul ends their relationship. She calmly accepts, having earlier concluded that he and Holly are in love. Holly schemes to marry Jose for his money, which angers Paul. After Holly receives a telegram notifying her of Fred's death, she trashes her apartment. Months later, Paul has moved out. He is invited to dinner by Holly, who is leaving the next morning for Brazil to continue her relationship with Jose. However, they are arrested in connection with Sally Tomato's drug ring, and Holly spends the night in jail. The next morning, Holly is released on bail and finds Paul waiting, and they take a cab. He has her cat and a letter from Jose explaining he must end their relationship due to her arrest. Holly insists she will go to Brazil anyway, asks the cab to pull over, and releases the

SOLUTION: What city does Holly live in?

PROBLEM: Parkinson's disease is the most common neurodegenerative movement disorder. The motor impairments of Parkinson's disease are caused by the loss of dopaminergic neurons in the substantia nigra and associated with the appearance of fibrillar aggregates of -synuclein (-syn) called Lewy bodies. Approximately 90% of -syn deposited in Lewy bodies is phosphorylated at serine 129 (Ser129). In contrast, only 4% or less of total -syn is phosphorylated at this residue in the normal brain. This suggests that the accumulation of Ser129-phosphorylated -syn leads to the formation of Lewy bodies and dopaminergic neurodegeneration in Parkinson's disease. Our laboratory and others have performed experiments using in vivo models of Parkinson's disease to elucidate the role of increased Ser129 phosphorylation in -syn neurotoxicity. However, there has been a lack of consistency among these models. In this review, we summarize the main findings regarding the relationship between Ser129 phosphorylation and -syn neurotoxicity, and examine the differences among models. We further discuss the role of Ser129 phosphorylation in -syn aggregation and the future directions to test the potential of Ser129 phosphorylation as a therapeutic target for slowing the progression of Parkinson's disease.

SOLUTION:
Which residue of alpha-synuclein was found to be phosphorylated in Lewy bodies?