Given a text passage, come up with an appropriate title for it. The title should accurately represent what the main focus of the passage is. The title of a passage may be present in the first few sentences of the passage and/or be referred to multiple times in the passage. The title should be 1-5 words long.
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Question: Down syndrome is one of the most common chromosome abnormalities in humans . It occurs in about one per 1000 babies born each year . In 2015 , Down syndrome was present in 5.4 million individuals and resulted in 27,000 deaths down from 43,000 deaths in 1990 . It is named after John Langdon Down , the British doctor who fully described the syndrome in 1866 . Some aspects of the condition were described earlier by Jean - Étienne Dominique Esquirol in 1838 and Édouard Séguin in 1844 . In 1957 , the genetic cause of Down syndrome , an extra copy of chromosome 21 , was discovered .

Answer: Down syndrome


Question: Heliocentrism is the astronomical model in which the Earth and planets revolve around the Sun at the center of the Solar System . Historically , Heliocentrism was opposed to geocentrism , which placed the Earth at the center . The notion that the Earth revolves around the Sun had been proposed as early as the 3rd century BCE by Aristarchus of Samos , but at least in the medieval world , Aristarchus 's Heliocentrism attracted little attention -- possibly because of the loss of scientific works of the Hellenistic Era .

Answer: Heliocentrism


Question: The stapes or stirrup is a bone in the middle ear of humans and other mammals which is involved in the conduction of sound vibrations to the inner ear . The stirrup - shaped small bone is on and transmits these to the oval window , medially . The stapes is the smallest and lightest named bone in the human body , and is so - called because of its resemblance to a stirrup ( Latin : Stapes ) .

Answer:
Stapes