instruction:
Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
question:
Question: Do novel meta-analysis-derived type 2 diabetes risk loci determine prediabetic phenotypes?
Answer: In contrast to the first series of GWA-derived type 2 diabetes candidate SNPs, we could not detect reliable associations of the novel risk loci with prediabetic phenotypes. Possible weak effects of ADAMTS9 SNP rs4607103 and VEGFA SNP rs9472138 on insulin sensitivity and insulin secretion, respectively, await further confirmation by larger studies.
answer:
no


question:
Question: Is cigarette smoking associated with a reduction in the risk of incident gout : results from the Framingham Heart Study original cohort?
Answer: Cigarette smoking is associated with lower incidence of gout and this is not explained by differences in the prevalence of risk factors. The mechanistic underpinnings of this epidemiological finding merits further study.
answer:
yes


question:
Question: Is granulocyte-macrophage colony-stimulating factor responsible for residual thrombopoiesis in mpl null mice?
Answer: There was no additional effect seen as a result of loss of betac signaling. GM-CSF did not play a significant role in thrombopoiesis, even in combination with the absence of thrombopoietin signaling. These results highlight problems that can be encountered when studying introduced mutations in mice. They exemplify the importance of eliminating the influence of modifying genes when attributing biologic differences to specific introduced genetic alterations.
answer:

no