In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Paragraph: Background: Human rhinoviruses (HRVs) are the most frequently detected pathogens in acute respiratory tract infections (ARTIs) and yet little is known about the prevalence, recurrence, structure and clinical impact of individual members. During 2007, the complete coding sequences of six previously unknown and highly divergent HRV strains were reported. To catalogue the molecular and clinical features distinguishing the divergent HRV strains, we undertook, for the first time, in silico analyses of all available polyprotein sequences and performed retrospective reviews of the medical records of cases in which variants of the prototype strain, HRV-QPM, had been detected. Methodology/Principle Findings: Genomic analyses revealed that the six divergent strains, residing within a clade we previously called HRV A2, had the shortest polyprotein of all picornaviruses investigated. Structure-based amino acid alignments identified conserved motifs shared among members of the genus Rhinovirus as well as substantive deletions and insertions unique to the divergent strains. Deletions mostly affected regions encoding proteins traditionally involved in antigenicity and serving as HRV and HEV receptor footprints. Because the HRV A2 strains cannot yet be cultured, we created homology models of predicted HRV-QPM structural proteins. In silico comparisons confirmed that HRV-QPM was most closely related to the major group HRVs. HRV-QPM was most frequently detected in infants with expiratory wheezing or persistent cough who had been admitted to hospital and required supplemental oxygen. It was the only virus detected in 65% of positive individuals. These observations contributed to an objective clinical impact ranging from mild to severe. The divergent strains did not meet classification requirements for any existing species of the genus Rhinovirus or Enterovirus. HRV A2 strains should be partitioned into at least one new species, putatively called Human rhinovirus C, populated by members detected with high frequency, from individuals with respiratory symptoms requiring hospital admission. 
 Title: Distinguishing Molecular Features and Clinical Characteristics of a Putative New Rhinovirus Species, Human Rhinovirus C (HRV C)
False

Paragraph: Background-Patients with the 2019 coronavirus disease have different degrees of psychological pain, such as anxiety and depression, which may related to their prognosis. Psychological intervention can be conducted in different ways to improve psychological pain and improve the treatment effect. Objective-The present study aimed to investigate and analyze the psychological status of patients with COVID-19 during the course of illness, and to evaluate the effect and influencing factors of psychological crisis intervention, so as to explore the effective mode of clinical psychological intervention in acute patients under isolation environment. Methods-A total of 143 persons participated in the study, including 26 patients diagnosed with COVID-19 in the isolation ward (COVID-19 group), 87 patients with general pneumonia in the observation ward (General Pneumonia group) and 30 healthy volunteers (Normal group). All the patients in the ward received comprehensive psychological intervention, including telephone psychological counseling (active and passive), self-adjustment of written materials and one-to-one psychological crisis intervention. Hamilton depression scale (HAMD) and Hamilton anxiety scale (HAMA) were used to evaluate the mental health status of all patients on the day of admission and 1 week after treatment. Results-The scores of HAMA and HAMD of all patients (including isolation ward and observation ward) were significantly higher than the healthy volunteers at the time of admission. The total score of HAMA and HAMD in CVOID-19 group were both higher than that General Pneumonia group. After 1 week`s hospitalization with comprehensive psychological intervention, the scores of HAMA and HAMD in CVOID-19 group were significantly decreased. Conclusion-Patients those who diagnosed with COVID-19 in the isolation ward and/or general pneumonia in observation ward have different degrees of anxiety, depression and sleep problems. While receiving antiviral treatment, patients also need psychological intervention. Comprehensive psychological intervention model has been proved to be effective. 
 Title: Analysis of psychological state and clinical psychological intervention model of patients with COVID-19 Running Title: Psychological state and intervention model in COVID-19 patients
True

Paragraph: and dromedary camels using dipeptidyl peptidase-4 (DPP4) as its receptor. The distribution of DPP4 in the respiratory tract tissues of humans and camels reflects MERS-CoV tropism. Apart from dromedary camels, insectivorous bats are suggested as another natural reservoir for MERS-like-CoVs. In order to gain insight on the tropism of these viruses in bats, we studied the DPP4 distribution in the respiratory and extra-respiratory tissues of two frugivorous bat species (Epomophorus gambianus and Rousettus aegyptiacus) and two insectivorous bat species (Pipistrellus pipistrellus and Eptesicus serotinus). In the frugivorous bats, DPP4 was present in epithelial cells of both the respiratory and the intestinal tract, similar to what has been reported for camels and humans. In the insectivorous bats, however, DPP4 expression in epithelial cells of the respiratory tract was almost absent. The preferential expression of Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in the human population in 2012 and has been causing multiple outbreaks of human disease, mainly in the Arabian Peninsula 1 . The dromedary camel (Camelus dromedarius) has been shown to be the reservoir host for primary human infections 2-8 , although other susceptible animals 9-11 , including bats 12,13 , are suspected also to be hosts for this virus. MERS-like-CoVs have been sequenced from bat samples, mainly from insectivorous bats, but they have not yet been successfully isolated 14-21 . Screening of over 5000 insectivorous bats from Ghana, Ukraine, Romania, Germany, and the Netherlands showed that MERS-CoV-like viruses were detected in 24.9% of Nycteris bats and 14.7% of Pipistrelle bats 17 . MERS-CoV uses dipeptidyl peptidase-4 (DPP4) as its receptor to infect its target cells, including bat cells 22 . Analysis of DPP4 sequences from different bat species and in-vitro infection studies with various bat cell lines suggested that multiple bat species are susceptible to MERS-CoV 12,21,23 . MERS-like-CoVs probably also use DPP4 as indicated by studies on the Tylonycteris bat CoV HKU4, one of the MERS-like-CoVs 21 . HKU4 uses DPP4 to infect both bat and human cells in vitro 24,25 . It is known that DPP4 is differently distributed in the respiratory tract of humans and other susceptible livestock animals, including dromedary camels 9,26 . DPP4 expression in the nasal epithelium of the camel, llama, and pig allows them to develop upper respiratory tract infection upon intranasal inoculation with MERS-CoV 2,9,26 , while in humans, DPP4 is exclusively expressed in the lower respiratory tract epithelium, which is in line with acute pneumonia being the main clinical outcome of MERS-CoV infection 26, 27 . Additionally, the absence of DPP4 expression in the upper respiratory tract epithelium of sheep renders this tissue to be non-susceptible in-vivo 9 . These data indicate that the localization of DPP4 expression in tissues reflects MERS-CoV susceptibility and tropism in vivo. The localization of DPP4 expression in bat tissues, however, has not been studied, unlike that in other MERS-CoV susceptible species 9,26 . Our study aimed to understand the tropism of MERS-like-CoVs in bats by mapping the distribution of DPP4 expression in tissues from four bat species. DPP4 immunohistochemistry staining was performed on tissues collected from two widespread insectivorous bat species in Europe and Asia, the common pipistrelle bat (Pipistrellus pipistrellus) and the serotine bat (Eptesicus serotinus) 28,29 ; and two common frugivorous bat species in Africa, i.e. Published: xx xx xxxx OPEN www.nature.com/scientificreports/ 2 Scientific RepoRts | 7: 1193 | the Gambian epauletted fruit bat (Epomophorus gambianus) and the Egyptian fruit bat (Rousettus aegyptiacus) 30,31 . These four bat species were chosen based on their interactions with humans as they roost and forage in the human habitat or serve as a human food source 28-31 . We show that DPP4 localization varies not only among MERS-CoV susceptible species 9,26 but also between bat species, which may imply variability in MERS-like-CoVs tropism, pathogenesis, and transmission route. 
 Title: Tissue Distribution of the MERS- Coronavirus Receptor in Bats OPEN

True