Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Input: Consider Input: Increased expression of nerve growth factor in injured or inflamed tissue is associated with increased pain. This proof-of-concept study was designed to investigate the safety and analgesic efficacy of tanezumab, a humanized monoclonal antibody that binds and inhibits nerve growth factor. We randomly assigned 450 patients with osteoarthritis of the knee to receive tanezumab (administered at a dose of 10, 25, 50, 100, or 200 g per kilogram of body weight) or placebo on days 1 and 56. The primary efficacy measures were knee pain while walking and the patient's global assessment of response to therapy. We also assessed pain, stiffness, and physical function using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC); the rate of response using the criteria of the Outcome Measures for Rheumatology Committee and Osteoarthritis Research Society International Standing Committee for Clinical Trials Response Criteria Initiative (OMERACT-OARSI); and safety. When averaged over weeks 1 through 16, the mean reductions from baseline in knee pain while walking ranged from 45 to 62% with various doses of tanezumab, as compared with 22% with placebo (P<0.001). Tanezumab, as compared with placebo, was also associated with significantly greater improvements in the response to therapy as assessed with the use of the patients' global assessment measure (mean increases in score of 29 to 47% with various doses of tanezumab, as compared with 19% with placebo; P0.001). The rate of response according to the OMERACT-OARSI criteria ranged from 74 to 93% with tanezumab treatment, as compared with 44% with placebo (P<0.001). The rates of adverse events were 68% and 55% in the tanezumab and placebo groups, respectively. The most common adverse events among tanezumab-treated patients were headache (9% of the patients), upper respiratory tract infection (7%), and paresthesia (7%). In this proof-of-concept study, treatment with tanezumab was associated with a reduction in joint pain and improvement in function, with mild and moderate adverse events, among patients with moderate-to-severe osteoarthritis of the knee. (Funded by Rinat Neuroscience; ClinicalTrials.gov number, NCT00394563.).

Output: What is the target of tanezumab?


Input: Consider Input: Toni Young (born January 11, 1991) is an American professional basketball player who last played for the New York Liberty of the WNBA.

Output: What team did Toni Young play for?


Input: Consider Input: After discovering that there are galaxies beyond the Milky Way, Edwin Hubble went on to measure the distance to hundreds of other galaxies. His data would eventually show how the universe is changing, and would even yield clues as to how the universe formed. If you look at a star through a prism, you will see a spectrum, or a range of colors through the rainbow. The spectrum will have specific dark bands where elements in the star absorb light of certain energies. By examining the arrangement of these dark absorption lines, astronomers can determine the composition of elements that make up a distant star. In fact, the element helium was first discovered in our Sun not on Earth by analyzing the absorption lines in the spectrum of the Sun. While studying the spectrum of light from distant galaxies, astronomers noticed something strange. The dark lines in the spectrum were in the patterns they expected, but they were shifted toward the red end of the spectrum, as shown in Figure 1.1. This shift of absorption bands toward the red end of the spectrum is known as redshift. Redshift is a shift in absorption bands toward the red end of the spectrum. What could make the absorption bands of a star shift toward the red? Redshift occurs when the light source is moving away from the observer or when the space between the observer and the source is stretched. What does it mean that stars and galaxies are redshifted? When astronomers see redshift in the light from a galaxy, they know that the galaxy is moving away from Earth. If galaxies were moving randomly, would some be redshifted but others be blueshifted? Of course. Since almost every galaxy in the universe has a redshift, almost every galaxy is moving away from Earth. Click image to the left or use the URL below. URL: Edwin Hubble combined his measurements of the distances to galaxies with other astronomers measurements of redshift. From this data, he noticed a relationship, which is now called Hubbles Law: the farther away a galaxy is, the faster it is moving away from us. What could this mean about the universe? It means that the universe is expanding. Figure 1.2 shows a simplified diagram of the expansion of the universe. One way to picture this is to imagine a balloon covered with tiny dots to represent the galaxies. When you inflate the balloon, the dots slowly move away from each other because the rubber stretches in the space between them. If you were standing on one of the dots, you would see the other dots moving away from you. Also, the dots farther away from you on the balloon would move away faster than dots nearby. In this diagram of the expansion of the universe over time, the distance between galaxies gets bigger over time, although the size of each galaxy stays the same. An inflating balloon is only a rough analogy to the expanding universe for several reasons. One important reason is that the surface of a balloon has only two dimensions, while space has three dimensions. But space itself is stretching out between galaxies, just as the rubber stretches when a balloon is inflated. This stretching of space, which increases the distance between galaxies, is what causes the expansion of the universe. One other difference between the universe and a balloon involves the actual size of the galaxies. On a balloon, the dots will become larger in size as you inflate it. In the universe, the galaxies stay the same size; only the space between the galaxies increases.


Output: as the universe expands it is the __________ that is expanding.