Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: Possible relationships between the white matter lesions and extrinsic toxic agents are discussed.

Output: non-adverse drug event


Input: Consider Input: Daptomycin is a lipopeptide antibiotic active against multidrug-resistant gram-positive organisms.

Output: non-adverse drug event


Input: Consider Input: Classification included dry (7%), mild (48%), moderate (39%), and severe (6%).


Output: non-adverse drug event