In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Q: Question: Indinavir is a selective inhibitor of HIV protease because: 
 Options:  <1> By hydrolysis, the active drug is generated. <2> Rents irreversibly the active center of the enzyme. <3> Its structure mimics the transition state of the reaction catalyzed by the enzyme. <4> It is a suicide inhibitor. <5> Its symmetric structure interacts effectively with the active center of the enzyme.

A: 3
****
Q: Question: In general, allosteric enzymes: 
 Options:  <1> They link the effectors in the active center. <2> They form covalent bonds with their negative effectors. <3> They originate hyperbolic curves of speed before the concentration of substrate. <4> They change their conformation when they link effectors. <5> They are irreversibly modified when they are inhibited.

A: 4
****
Q: Question: It gives the plasma membrane high water permeability: 
 Options:  <1> Aquaporins. <2> Ionic channels. <3> Na + / K + -ATPase. <4> Cl / HCO3 exchanger. <5> Its lipid composition.

A:
1
****