In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
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Question: Paragraph: The Mediterranean diet is rich in fruits and vegetables, monounsaturated fatty acids from olive oil, and is complemented with the traditional use of culinary and medicinal herbs and spices. An important feature of this diet is the negative association with the incidence of metabolic syndrome, which is characterized by increased risk of cardiovascular disease. Conformity to the Mediterranean diet has also been linked to a decreased risk of cardiovascular disease and cancer in US populations. Plants that originated in the Mediterranean basin have been used for centuries in botanical therapies. Many of these plants are believed to prevent and/or cure a wide spectrum of ailments based on their content in bioactive components that exert anti-oxidant, anti-infl ammatory, anticarcinogenic, anti-diabetic, and anti-thrombotic functions. This chapter underlines the health benefi ts that may derive from utilization through dietary assumption or medicinal applications of a selected group of plant products including extracts and specifi c bioactive components found in rosemary, licorice, chamomile, and olive oil. Each section provides a scientifi c analysis of the most recent literature and attempts to highlight the mechanisms of action and molecular targets of bioactive components derived from these plants. 
 Title: Health Benefi ts of Traditional Culinary and Medicinal Mediterranean Plants

Answer: False


Question: Paragraph: The synthesis of racemic substituted 7-amino-5,7,8,9-tetrahydrobenzocyclohepten-6-one hydrochlorides was optimized to enhance reproducibility and increase the overall yield. In order to investigate their specificity, series of enzyme inhibition assays were carried out against a diversity of proteases, covering representative members of aspartic, cysteine, metallo and serine endopeptidases and including eight members of the monometallic M1 family of aminopeptidases as well as two members of the bimetallic M17 and M28 aminopeptidase families. This aminobenzosuberone scaffold indeed demonstrated selective inhibition of M1 aminopeptidases to the exclusion of other tested protease families; it was particularly potent against mammalian APN and its bacterial/parasitic orthologues EcPepN and Pf AM1. 
 Title: molecules Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases

Answer: True


Question: Paragraph: , are considered to be responsible for tumor growth and chemoresistance. Different hypotheses have been proposed to explain the origin of CICs, including mutations in adult stem/ progenitor cells or the acquisition of stem-like characteristics in differentiated cells; however, studies have yielded conflicting identification for CICs and have little information for the origin to generate CICs. Part of the difficulty in identifying CICs may stem from the fact that the CICs studied have been largely derived from cancer cell lines or well-developed tumors. In previous studies, we have reported the enrichment of mouse pulmonary stem/progenitor cells (mPSCs) by using serumfree primary selection culture followed by FACS isolation using the coxsackievirus/ adenovirus receptor (CAR) as the positive selection marker. Here, we demonstrated that overexpression of the pluripotent transcription factor Oct-4 is sufficient to induce CAR + /mPSCs transformation, which we name CAR + /mPSCs Oct-4_hi . These transformed cells possess cancer initiating and chemoresistance potential, as well as exhibiting remarkable expression of certain proangiogenic factors, including angiopoietins (ANGs) and VEGF, and enhanced angiogenic potential. Moreover, CAR + /mPSCs Oct-4_hi actively participated in tumor blood vessel formation and triggered a novel angiogenic mechanism, the angiopoietins/Tie2 signaling pathway. These study provide critical evidence supporting the possible origin to generate CICs, and help elucidate the pathways responsible for CICs-mediated blood vessel formation. 
 Title: Acquisition of tumorigenic potential and enhancement of angiogenesis in pulmonary stem/progenitor cells through Oct-4 hyperexpression

Answer:
False