Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Ex Input:
Paragraph: Cuomo’s cautiously upbeat report at a daily briefing came as the daily death toll across the state, the epicenter of the pandemic in the United States, dropped to 540 on April 17, down from 630 a day earlier and the lowest in more than two weeks. The governor said total hospitalizations of patients being treated for COVID-19, the respiratory illness caused by the coronavirus, came to 16,967, a drop of more than 1,300 over the past three days. Intubations and admissions to intensive care units also continued on their downward trend. “If you look at the past three days, you could argue that we are past the plateau and we’re starting to descend which would be very good news,” Cuomo said. He said, however, that about 2,000 infected people were newly admitted to hospitals on Friday, which he characterized as “still an overwhelming number,” and reiterated that he would take a cautious approach to reopening businesses and schools. Cuomo repeated a call for the federal government to help coordinate and provide funding for the mass testing that he and other governors have said is needed to determine when it is safe for people to go back to work. Providing new details on the challenge, Cuomo said a survey of labs in his state revealed an inability to procure the chemical reagents needed to run the tests on machines supplied by private manufacturers like Roche Holding AG. “They bought the machine, they have the machine, they have the test, but they need the reagents to do a higher volume of tests,” Cuomo said, adding that makers like Roche are struggling to get the reagents from China. “That’s the logjam we are in.”  New York disclosed 7,090 new positive cases over the last 24 hours for a total of 236,732 cases, while deaths increased by 540 to 13,362, marking by far the largest number of fatalities of any state. Even with stabilizing numbers, Cuomo said the pandemic was taking a severe emotional and economic toll on people, and estimated the impact on society would prove to be the biggest challenge facing the country since World War Two. “On every level this is a terrible experience, Cuomo said. “It is as tumultuous a time as we have ever seen.” Claim: New York Governor sounds optimistic note as coronavirus numbers improve.

Ex Output:
New York Governor Andrew Cuomo said on Saturday that a recent drop in hospitalizations and other improving metrics indicated the state may be past the peak of its coronavirus crisis and on a path toward stabilizing its battered healthcare system.


Ex Input:
Paragraph: Urinary incontinence or loss of bladder control is by far  the most common problem, and childbirth, which can weaken  pelvic floor muscles, is the most frequent cause. “What stands out is such a large number of women had  symptoms of a moderate-to-severe pelvic floor disorder,” said  Dr. Ingrid Nygaard of the University of Utah, whose study  appears in Journal of the American Medical Association. “We know many women leak urine once in a blue moon if they  are doing strenuous exercise. That such a large number leaks on  a regular basis was surprising to see,” she said by telephone. Nygaard’s team studied 1,961 nonpregnant women aged 20 and  older who were part of a national health survey in 2005-2006. They were examined for symptoms of urinary and fecal  incontinence and pelvic organ prolapse, in which an organ such  as the bladder drops and pushes against the walls of the  vagina. Overall, 23.7 percent of women reported symptoms of at  least one pelvic floor disorder. Of these, 15.7 percent had  urinary incontinence, 9 percent had fecal incontinence and 2.9  percent had pelvic organ prolapse, in which women reported  seeing or feeling a vaginal bulge. Age plays a major role, with just 10 percent of women 20 to  39 reporting at least one disorder, compared with about a  quarter of women 40 to 59, 37 percent of women 60 to 79, and  nearly half of women 80 and older. Women were considered to have urinary incontinence if they  had at least weekly leakage, or monthly leakage of volumes of  more than just a few drops. If women with occasional leakage were included, the numbers  might be much higher, the researchers said. “The study results underscore the need to identify the  causes of pelvic floor disorders and the means to prevent and  treat them,” Dr. Duane Alexander, director of the National  Institute of Child Health and Human Development, said in a  statement. Treatments for urinary stress incontinence — the kind  linked with laughing, coughing, sneezing or exercise — range  from exercises to surgical options. Urge incontinence or overactive bladder can be treated by  lifestyle changes and a number of drugs, including tolterodine  or Detrol made by Pfizer Inc; Vesicare or solifenacin made by  GlaxoSmithKline and Astellas Pharma Inc; and Enablex or  darifenacin by Novartis AG. Claim: Pelvic disorders common among women: study.

Ex Output:
Nearly one quarter of all U.S. women  have some sort of pelvic floor disorder such as urinary or  fecal incontinence, and more cases are likely as the population  ages, researchers said on Tuesday.


Ex Input:
Paragraph: Almost three years after he received bone marrow stem cells from a donor with a rare genetic mutation that resists HIV infection - and more than 18 months after he came off antiretroviral drugs - highly sensitive tests still show no trace of the man’s previous HIV infection. “There is no virus there that we can measure. We can’t detect anything,” said Ravindra Gupta, a professor and HIV biologist who co-led a team of doctors treating the man. AIDS experts said the case is a proof of the concept that scientists will one day be able to end AIDS, and marks a “critical moment” in the search for an HIV cure, but does not mean that cure has already been found. Gupta described his patient as “functionally cured” and “in remission”, but cautioned: “It’s too early to say he’s cured.”  The man is being called “the London patient”, in part because his case is similar to the first known case of a functional cure of HIV - in an American man, Timothy Brown, who became known as the Berlin patient when he underwent similar treatment in Germany in 2007 which also cleared his HIV. Brown, who had been living in Berlin, has since moved to the United States and, according to HIV experts, is still HIV-free. Some 37 million people worldwide are currently infected with HIV and the AIDS pandemic has killed about 35 million people worldwide since it began in the 1980s. Scientific research into the complex virus has in recent years led to the development of drug combinations that can keep it at bay in most patients. Gupta, now at Cambridge University, treated the London patient when he was working at University College London. The man had contracted HIV in 2003, Gupta said, and in 2012 was also diagnosed with a type of blood cancer called Hodgkin’s Lymphoma. In 2016, when he was very sick with cancer, doctors decided to seek a transplant match for him. “This was really his last chance of survival,” Gupta told Reuters. The donor - who was unrelated - had a genetic mutation known as ‘CCR5 delta 32’, which confers resistance to HIV. The transplant went relatively smoothly, Gupta said, but there were some side effects, including the patient suffering a period of “graft-versus-host” disease - a condition in which donor immune cells attack the recipient’s immune cells. Most experts say it is inconceivable such treatments could be a way of curing all patients. The procedure is expensive, complex and risky. To do this in others, exact match donors would have to be found in the tiny proportion of people — most of them of northern European descent — who have the CCR5 mutation that makes them resistant to the virus. “Although this is not a viable large-scale strategy for a cure, it does represent a critical moment,” said Anton Pozniak, president of the International AIDS Society. “The hope is that this will eventually lead to a safe, cost-effective and easy strategy...using gene technology or antibody techniques.”  Specialists said it is also not yet clear whether the CCR5 resistance is the only key - or whether the graft-versus-host disease may have been just as important. Both the Berlin and London patients had this complication, which may have played a role in the loss of HIV-infected cells, Gupta said. His team plans to use these findings to explore potential new HIV treatment strategies. “We need to understand if we could knock out this (CCR5) receptor in people with HIV, which may be possible with gene therapy,” he said. The London patient, whose case was set to be reported in the journal Nature and presented at a medical conference in Seattle on Tuesday, has asked his medical team not to reveal his name, age, nationality or other details. Claim: London HIV patient becomes world's second AIDS cure hope.

Ex Output:

An HIV-positive man in Britain has become the second known adult worldwide to be cleared of the AIDS virus after he received a bone marrow transplant from an HIV-resistant donor, his doctors said.