Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
The reaction subsided after treatment with diphenhydramine and dexamethasone.

Ex Output:
non-adverse drug event


Ex Input:
A patient with an allergy to a macrolide antibiotic was given tacrolimus and developed a sudden cutaneous reaction.

Ex Output:
adverse drug event


Ex Input:
The ability of clozapine to suppress tardive dyskinesia symptoms raises the possibility that clozapine, at least at the doses used in this report, might also induce the disorder.

Ex Output:

non-adverse drug event