Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: The two patients were successfully treated with pharmacological thrombolysis with no recurrence.

Output: non-adverse drug event


Input: Consider Input: We know of no other reported cases of spontaneous muscle necrosis in association with diabetes insipidus and feel that there should be increased awareness of the association between the two.

Output: non-adverse drug event


Input: Consider Input: Nifedipine may induce, or aggravate, pre-existing, gastro-oesophageal reflux.


Output: adverse drug event