TASK DEFINITION: Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.
PROBLEM: This release makes no mention of the costs of the drugs compared in this study, even though the drugs have been in use for years and are widely available. Since the study is a comparison of various treatments for this form of cancer, it seems relevant to offer a cost comparison as well as a comparison of efficacy. It appears that the high dose methotrexate is given over a 24-hour period, presumably in the hospital, while the standard methotrexate is given as a single dose. Also, the high dose methotrexate is followed by leucovorin administration while the standard dose is not. According to the site GoodRx, the cost for methotrexate in low-dose (2.5 mg) pill form averages out to about $50 for a month’s supply. Newer, injectable variations of the drug cost upwards of $500 a month for the 25 mg dose. The release states that patients receiving high doses of the drug methotrexate “had a significantly better outcome, by 5 to 6 percent” than did patients receiving the current standard of care, which is gradually escalating doses of the drug. The release also explains that patients nine years old or younger who were also treated with a steroid called decadron (dexamethasone) for half as long as normal (14 versus 28 days) benefited from the treatment while patients 10 and older did not. We’re not sure of the meaning behind these results as portrayed in the release. Which outcome was better by 5 or 6 percent? The study has several. Does that mean the relapse rate was reduced or is it the event free survival that was better? It would be more meaningful to readers if the release had included the actual relapse and event free survival rates for each group analyzed in terms most people can understand. For example: “relapse rates were 5 percent lower in Group X compared to Group Y.” We’ll give this category a satisfactory rating largely due to the release including information that patients 10 and older receiving dexamethasone “were at much higher risk for a debilitating bone condition called osteonecrosis,” although we would have been happier if that greater risk would have been quantified. However, the published study explains that there were toxicity problems beyond that of dexamethasone and the release would have been stronger including that information as well. The release stated the study was randomized and controlled, and provides a broad overview of the study design, for which we give the release a borderline satisfactory under this criteria. However, these are the superficial results. On deeper delving into the study methodology, the statistical significances of the results were very close to not statistically significant. This is due to their planned interim stopping of the treatment and the fact that they were looking at multiple outcomes in multiple groups. This release doesn’t demonstrate disease-mongering. While the release does say that this clinical trial was run by the Children’s Oncology Group, which is funded by the National Cancer Institute and the National Institutes of Health, it makes no mention of possible conflicts of interest. Compounding that is the fact that the published study says, “Disclosures provided by the authors are available with this article at www.jco.org,” but that information is behind the journal’s paywall for most readers, so it’s unknown if there is, or is not, a conflict. It appears as though five of the authors (out of a total of about 20) have some conflicts of interest, mostly from several types of drug company payments. The release is comparing the efficacy of treatment regimens using different drugs so alternative treatments for B-acute lymphoblastic leukemia are noted. The release makes clear at the end that the treatment of this disease is improving thanks to refinement of the use of existing drug treatments, meaning that they are readily available for patient use. The release suggests the study findings could change the way childhood leukemia is treated. Modifying existing treatments to enhance a patient’s survival is certainly novel enough to warrant a release. There is no use of unjustifiable language in this release. However, the tone may be a bit overly optimistic given the study findings.

SOLUTION: Relapses of childhood leukemia improve with high doses of common chemo drug

PROBLEM: Since Nov. 1, South Carolina has recorded 86 reported cases of the contagious disease. State Epidemiologist Linda Bell said Monday that’s more than four times what state officials normally expect to see. Over the last 10 years, South Carolina averaged 19 reported cases of hepatitis A annually. Most of the new cases have occurred in Aiken County, and almost half of all cases involve individuals who reported drug use, Bell said. Still, the general population needn’t be overly concerned, she said. “But we are seeing cases higher that what we expect to see,” Bell said. “And so it’s important for us to do our prevention efforts early to reach those high-risk groups, get them vaccinated ... so that we can prevent” a severe outbreak. The State reports the Department of Health and Environmental Control is offering no-cost vaccines to high risk groups including drug users, homeless, formerly incarcerated and sexually-active gay men. Additionally, health officials recommend all children get two doses of the vaccine as part of their immunization schedule. Of the 86 reported cases in South Carolina, 59 have led to hospitalization and one resulted in death, the DHEC said. Hepatitis is a disease characterized by inflammation of the liver. It comes in many forms, including hepatitis A, B and C. As a result, individuals with chronic liver disease, like cirrhosis, are at increased risk of complications if infected and should be vaccinated. The virus-borne infection can be prevented by vaccination and is usually transmitted person-to-person through consumption of contaminated food or water, according to the U.S. Centers for Disease Control and Prevention. Antibodies produced in response to hepatitis A infection last for life and protect against reinfection. Infection usually results in sickness in two to six weeks after exposure. Symptoms include fatigue, loss of appetite, stomach pain, nausea, and yellowing of the eyes and skin. Symptoms usually resolve within two months of infection, according to the CDC. State public health officials in February declared an outbreak in Aiken County after an employee at a second restaurant in Aiken tested positive for the virus, the DHEC said. Bell, though, stressed transmission by food or beverage is uncommon. “Most transmission in the United States is through person-to-person contact,” Bell said. “Good hygiene - diligently washing your hands - is a good way to prevent hepatitis A, as well as not sharing personal items,” including drug equipment, she said, adding the state has received reports of hepatitis A from people using various drugs, “everything from marijuana to meth.” Residents can schedule an appointment for a vaccination at their local health department by calling 855-472-3432 or going to http://bit.ly/2HhEsM8 . ___ Information from: The State, http://www.thestate.com

SOLUTION: South Carolina declares hepatitis outbreak.

PROBLEM: "South Florida has a reputation as a place ripe for fraud and crime -- including bilking the government. State Rep. Ron Saunders, the Democratic minority leader from Key West, has slapped a more specific label on a costly problem in South Florida: Medicaid fraud. ""The two worst counties for fraud in the country -- not state -- are Dade and Broward county,"" he told a roomful of reporters on Jan. 19, 2011, during an Associated Press preview of Florida's upcoming legislative session. It's easy to find news articles describing South Florida as a mecca for such fraud -- with labels such as ""ground zero"" or mind-boggling tales of abuse. But the word ""worst"" caught our eye -- are the South Florida counties of Miami-Dade and Broward truly the ""worst"" in the country for Medicaid fraud? Medicaid, a health care program for low-income individuals, is administered by the states and receives some federal funding. The Truth-O-Meter has weighed in multiple times on fact-checks related to the high cost and growth of Medicaid, including a claim by Pam Bondi, now Florida's attorney general, and Bill McCollum, Florida's previous attorney general. For more background, check out this website of the federal Centers for Medicare and Medicaid Services. We spoke to Saunders directly on Jan. 20, who told us that his statement was in response to a question about how to resolve the state's budget crisis. Saunders said it's a ""no-brainer"" to cut back on fraud such as in Medicare and Medicaid rather than make more cuts in areas such as education. But after a lot of calls and research, we can say one thing for certain: Nobody tracks county-by-county Medicaid fraud nationally. Even within Florida, a county breakdown is not available. So we're going to rely on expert opinions and documented trends in this ruling. Mark Hollis, spokesperson for the House Democratic caucus, sent us links to newspaper articles and government reports about Medicaid fraud in South Florida. Among the sources Hollis cited was a March 2009 article in Health News Florida, quoting state Sen. Don Gaetz saying: ""Since we have the worst problem in the nation, we need the most effective solution."" Hollis also sent us a December 2005 article in HomeCare, an industry publication, quoting FBI agent Michael Clemens, who was in charge of the Miami field office at the time, saying: ""South Florida is ground zero for health care fraud."" But neither article provides any documentation to support that ""worst"" label. Hollis also sent us links to a House bill and recent government reports about Medicaid fraud. House Bill 1487 in 2009, which labeled Miami-Dade an area of ""special concern,"" was intended to rein in Medicaid fraud. The Senate version, Senate Bill 2658, was signed into law in June 2009. The staff analysis outlined the rampant growth in home health care agencies in Florida: Of the 431 licensure applications in 2007, 58.5 percent were in Miami-Dade. In that county, the number of licensed agencies grew 414 percent between August 1999 and March 6, 2009. The analysis also stated that ""While Miami-Dade has about 20 percent of Florida’s Medicaid population and about 33 percent of Florida’s residents over the age of 60, 91 percent of the state reimbursement for certain home health services were going to Miami-Dade."" While the bill analysis doesn't provide data ranking all of Florida's counties, it certainly suggests that Miami-Dade has an overwhelmingly disproportionate share of Medicaid dollars -- and fraud. Florida's Agency for Health Care Administration, which administers the Medicaid program, has a report from 2009-10 that also provides some insight. Although the 94-page report does not describe Broward and Miami-Dade as the worst in the nation, it noted:  • ""Home health agencies have been an acknowledged area of health care fraud in recent years. For the four fiscal years ending June 30, 2009, approximately 90 percent of Medicaid expenditures for home health aide visits were made to providers in Miami‐Dade County, while only about 20 percent of Medicaid recipients reside in that area. At the end of the fiscal year, there were 339 home health agencies in Miami‐Dade County actively enrolled in the Medicaid program and only 293 in the other 66 counties combined."" (Page 53)  • Statutes were changed in 2008 and 2009 to address home-health fraud. Forty-seven licensure denials for home health agencies were upheld in FY 2009-10 for fraud-related reasons. Thirty-one of the denials (66 percent) were in Miami-Dade County. (Page 65)  We reached out to several agencies that have a role in Medicaid. Both the Florida Attorney General, which has a Medicaid Fraud Control Unit, and AHCA said they had no nationwide county-by-county information to support or refute Saunders' claim. Don White, spokesman for the Office of Inspector General for the U.S. Department of Health and Human Services, also told us that the federal government has ""no statistics on Medicaid fraud."" As for Saunders' claim that Dade and Broward are the ""worst"" in the country, White said: ""Do we have the numbers? No. Is he probably correct? Yes."" We ran Saunders' claim by Alan Levine, a former secretary at AHCA under Gov. Jeb Bush and an expert on Medicaid. ""I have absolutely no doubt South Florida is among the highest,"" Levine wrote in an e-mail. ""Others that likely run in the same circle are New York and New Jersey. But South Florida, from all the experience I have, clearly leads the way."" Levine sent us a 2009 report, ""Stop Paying the Crooks,"" by the Center for Health Transformation, an organization founded by former House Speaker Newt Gingrich. It stated that the U.S. Department of Justice labeled ""South Florida -- and more specifically, Miami-Dade County --Ground Zero for health care fraud in America."" But no numbers ranking counties nationwide. We sent Saunders' claim to Craig Smith, the attorney who wrote the South Florida chapter, who works at Hogan Lovells law firm in Miami. ""Whatever the exact figure is, there can be no question that the bulk of the fraud, waste and abuse is occurring in Miami-Dade and Broward counties,"" Smith wrote to us in an e-mail Feb. 1. ""Based on the size of Florida's Medicaid program, you can fairly eliminate about 45 states from the comparative discussion."" So let's review: Saunders said that ""The two worst counties for (Medicaid) fraud in the country -- not state -- are Dade and Broward county."" We could not find any government office that could point to numbers ranking counties across the nation in terms of Medicaid fraud. But we found four experts -- one from the federal Department of Health and Human Services Office of Inspector General, one a former secretary of the state's AHCA, a spokesperson from a national organization that provides information on health care fraud and an attorney who specializes in health care law -- who all agree that Saunders is likely right. At PolitiFact Florida, we dig for data to support claims by politicians -- and Saunders and our experts haven't provided hard numbers to prove him right. But the fact that four experts -- including one appointed by a Republican governor -- generally back up the Democratic minority leader or say that the two counties are at least among the worst in the nation carries weight with us."

SOLUTION:
The two worst counties for (Medicaid) fraud in the country -- not state -- are Dade and Broward county.