Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Is serum Reg-Ialpha suitable marker of metabolic syndrome?
Answer: Our study, for the first time, indicates that serum Reg-1alpha is not useful for the diagnosis of metabolic syndrome (Tab. 3, Ref. 7).
no

Question: Is retinol-binding protein-4 strongly associated with insulin sensitivity in normal pregnancies?
Answer: The increased fat mass and insulin resistance during normal pregnancy was best explained by measures of fat mass. However, the increase in RBP4 from early to late pregnancy, associated with a decline in insulin sensitivity, potentially indicates interactions with glucose metabolism.
no

Question: Is the modulation of B16BL6 melanoma metastasis directly mediated by cytolytic activity of natural killer cells in alcohol-consuming mice?
Answer: These data suggest that the presence of the beige mutation diminishes the antimetastatic effect of alcohol consumption and that there is no interaction between alcohol consumption and NK-cell activity in the modulation of lung metastasis of B16BL6 melanoma cells.

no