Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Input: Consider Input: When the order was restored, Murad Pasha marched against Abbas I who was in Tabriz in 1610. Although the two armies met in Accay, north of Tabriz, no engagement or action took place. Due to the problems in the logistics, supply chain and the approaching winter Murad Pasha withdrew his forces to Diyarbakr. While being engaged in diplomatic correspondence with Abbas I for peace and preparing his army for another campaign at the same time he died on 5 August 1611 when he was older than 90. Nasuh Pasha was appointed as the new grand vizier and the commander of the eastern armies. He sued for peace, too, and accepted the proposal of the Safevid side in 1611. The Treaty of Nasuh Pasha was signed on 20 November 1612. The agreement secured the 1555 borders envisaged by the Peace of Amasya. Shah Abbas however, committed himself to send 200 bales of raw silk annually.

Output: Which happened first, Murad marching against Abbas or the signing of the Treaty of Nasuh Pasha?


Input: Consider Input: Chronic myeloid leukemia (CML) is caused by Bcr-Abl, a constitutively active tyrosine kinase that is the result of a reciprocal translocation between chromosomes 9 and 22 and cytogenetically evident as the Philadelphia chromosome. Imatinib (Glivec, Gleevec), a specific small molecule inhibitor of Bcr-Abl, has become the standard drug therapy for CML, and has dramatically diminished the use of allogeneic stem cell transplantation. Despite unprecedented rates of complete cytogenetic response, residual disease remains detectable in the majority of patients, suggesting that imatinib fails to eradicate leukemic stem cells. In this publication, the current perspectives for CML patients treated with imatinib are reviewed, focusing on the results of both standard and high-dose therapy. Monitoring of time-dependent prognostic factors is reviewed. The reasons imatinib may not be able to eradicate the disease are discussed, and potential strategies to achieve disease elimination are presented. Lastly, resistance to imatinib and the potential of second-generation Abl kinase inhibitors in the setting of clinical resistance are considered.

Output: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?


Input: Consider Input: Empirical data have challenged chronic posttraumatic stress disorder (PTSD) consisting of three dimensions. In the present study we aimed to determine the factor structure of acute posttraumatic symptoms in two recently traumatized samples. In sample 1, 203 civilian trauma survivors were administered the Davidson Trauma Scale (DTS) approximately 1 week posttrauma. In sample 2, 182 civilian treatment seeking trauma survivors completed the DTS at an average of 41.4 days posttrauma. Our confirmatory factor analyses indicated that a 4-factor intercorrelated model provided the best representation of the data in both samples. The four factors are best described as reexperiencing, active avoidance, dysphoria, and hyperarousal. For acute posttraumatic symptoms, the empirical data suggest to split the avoidance cluster into 'Active avoidance' and 'Dysphoria'-confirming findings in studies on chronic PTSD. In future revisions of the DSM, the diagnostic criteria for PTSD may need to be adapted to fit the research findings.


Output: Symptoms of which disorder are evaluated with the Davidson Trauma Scale?