In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[EX Q]: Question: The denaturation of proteins: 
 Options:  <1> It is accompanied by the loss of their activity. <2> It supposes the rupture of peptide bonds. <3> It is always an irreversible process. <4> Alter its primary structure. <5> It is carried out by chaperone proteins.
[EX A]: 1

[EX Q]: Question: When performing a central peripheral insertion venous catheterization procedure, the nurse must take into account that: 
 Options:  <1> The catheter is ready for use immediately after insertion, not needing further checks. <2> It is vital to perform a chest X-ray and / or an electrocardiographic record prior to its use. <3> A complete electrocardiogram should be performed in order to avoid possible complications. <4> The location of the tip of the catheter is only checked if parenteral nutrition is to be administered through it. <5> You need to check your position using a chest x-ray and another abdomen.
[EX A]: 2

[EX Q]: Question: A 60-year-old patient who came to the hospital's emergency department due to a left chest pain, cough and yellowish sputum, a temperature of 38.7ºC, a sensation of shortness of breath. Artificial saturation of 02 80%. Hemogram leukocytes 12000 / uL with 86% polymorphonuclear cells. Chest x-ray: alveolar infiltrate on the left base with air bronchogram. On suspicion of pneumonia, pneumococcal Ag is made in urine, which is positive and sputum culture is sent to the Microbiology service. Which empirical antibiotic treatment of the indicated ones is more correct in expectation of microbiological results? 
 Options:  <1> Ceftazidime <2> Clarithromycin <3> Azithromycin <4> Ceftriaxone <5> Doxycycline
[EX A]:
4