Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Ex Input:
Leke III Dukagjini (1410--1481), mostly known as Leke Dukagjini, was a mysterious member of the Dukagjini family about whom little is known and who is thought to have been a 15th-century Albanian nobleman.

Ex Output:
What was the noble family that Lekë Dukagjini was from?


Ex Input:
Lack of the yeast Rrm3p DNA helicase causes replication defects at multiple sites within ribosomal DNA (rDNA), including at the replication fork barrier (RFB). These defects were unaltered in rrm3 sir2 cells. When the RFB binding Fob1p was deleted, rrm3-generated defects at the RFB were eliminated, but defects at other rDNA sites were not affected. Thus, specific protein-DNA complexes make replication Rrm3p-dependent. Because rrm3-induced increases in recombination and cell cycle length were only partially suppressed in rrm3 fob1 cells, which still required checkpoint and fork restart activities for viability, non-RFB rrm3-induced defects contribute to rDNA fragility and genome instability.

Ex Output:
What is the effect of the absence of Saccharomyces cerevisiae Rrm3p?


Ex Input:
The King Willem-Alexander Canal (Dutch: Koning Willem-Alexanderkanaal), named after King Willem-Alexander of the Netherlands, is a 6 km long canal in the northeastern Netherlands.

Ex Output:

Who is the King Willem-Alexander Canal named after?