Given scientific fact as input, generate the question from this fact such that it can be answered from the input.

[EX Q]: Environmental changes is most responsible for the extinction of most species of plants and animals that have lived on earth.
[EX A]: What process is most responsible for the extinction of most species of plants and animals that have lived on Earth?

[EX Q]: The ileocecal valve, a sphincter, is usually in a constricted state, but when motility in the ileum increases, this sphincter relaxes, allowing food residue to enter the first portion of large intestine.
[EX A]: The ileocecal valve, a sphincter, is usually in a constricted state, but when motility in the ileum increases, this sphincter relaxes, allowing food residue to enter the first portion of what?

[EX Q]: To solubilize the fats so that they can be absorbed, the gall bladder secretes a fluid called bile into the small intestine.
[EX A]:
To solubilize the fats so that they can be absorbed, what organ secretes a fluid called bile into the small intestine?