TASK DEFINITION: In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
PROBLEM: Paragraph: We report on the development of an on-chip RPA (recombinase polymerase amplification) with simultaneous multiplex isothermal amplification and detection on a solid surface. The isothermal RPA was applied to amplify specific target sequences from the pathogens Neisseria gonorrhoeae, Salmonella enterica and methicillin-resistant Staphylococcus aureus (MRSA) using genomic DNA. Additionally, a positive plasmid control was established as an internal control. The four targets were amplified simultaneously in a quadruplex reaction. The amplicon is labeled during on-chip RPA by reverse oligonucleotide primers coupled to a fluorophore. Both amplification and spatially resolved signal generation take place on immobilized forward primers bount to expoxysilanized glass surfaces in a pump-driven hybridization chamber. The combination of microarray technology and sensitive isothermal nucleic acid amplification at 38°C allows for a multiparameter analysis on a rather small area. The on-chip RPA was characterized in terms of reaction time, sensitivity and inhibitory conditions. A successful enzymatic reaction is completed in <20 min and results in detection limits of 10 colony-forming units for methicillin-resistant Staphylococcus aureus and Salmonella enterica and 100 colony-forming units for Neisseria gonorrhoeae. The results show this method to be useful with respect to point-of-care testing and to enable simplified and miniaturized nucleic acid-based diagnostics. 
 Title: Multiplex isothermal solid-phase recombinase polymerase amplification for the specific and fast DNA-based detection of three bacterial pathogens

SOLUTION: True

PROBLEM: Paragraph: Feedback from operational stakeholders who manage or respond to outbreaks is that they are often too busy to review literature or obtain relevant background information to assist them with acute response. Unlike a traditional analytical outbreak investigation report, Watching Briefs are intended as a rapid resource for public health or other first responders in the field on topical, serious or current outbreaks, and provide a digest of relevant information including key features of an outbreak, comparison with past outbreaks and a literature review. They can be completed by responders to an outbreak, or by anyone interested in or following an outbreak using public or open source data, including news reports. 
 Title: Watching brief Title Wuhan novel coronavirus 2019nCoV

SOLUTION: False

PROBLEM: Paragraph: 【摘要】 背景与目的 自身抗体作为新的肿瘤标志物在肺癌的早期诊断和预后评价中可能发挥重要作用，本 研究利用多肽芯片检测非小细胞肺癌患者血清中表皮生长因子受体(epidermal growth factor receptor, EGFR)的自身抗 体，并筛选自身抗体识别的抗原表位。方法 使用Intavis公司ASPSL多肽芯片合成仪合成EGFR多肽芯片，利用多肽芯 片检测非小细胞肺癌患者血清中EGFR自身抗体，并筛选自身抗体识别的抗原表位。结果 使用EGFR多肽芯片检测 了20例非小细胞肺癌患者，结果有6例阳性，阳性率为30%，在该6例阳性患者中发现了9个高频位点，并且有8个高 频位点集中在EGFR胞外段的第III和第IV结构域。结论 本研究为我们进一步研究EGFR和EGFR自身抗体的功能提供 了新的线索。 【关键词】 肺肿瘤；EGFR；多肽芯片；自身抗体 【中图分类号】 R734.2 【Abstract】 Background and objective Autoantibodies as new tumor markers may play an important role in the early diagnosis and evaluating the prognosis of lung cancer. In this study, we detect epidermal growth factor receptor (EGFR) autoantibodies using peptide array and screen the epitopes which are recognized by EGFR autoantibodies. Methods Peptide array covering the extracellular domain of EGFR protein was synthesized by a synthesizer (ASPSL) made by Intavis company. EGFR autoantibodies in the serums of non-small cell lung cancer patients was detected using peptide array. Results Six of 20 patients were found to have EGFR autoantibodis. The positive rate is 30%. Nine high frequency spots were found in the 6 positive patients and 8 high frequency spots clustered in the III and IV domains. Conclusion These findings will offer new clues for the futher studies of EGFR and EGFR autoantibodies. 
 Title: 应用多肽芯片研究非小细胞肺癌患者血清中 的EGFR自身抗体 李元 岳文涛 王玥 张丽娜 顾勐 许绍发 Detecting EGFR Autoantibodies in Serums of NSCLC Patients with Peptide Array

SOLUTION:
True