Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Q: Question: Is central venous saturation an alternative to mixed venous saturation during cardiopulmonary bypass in coronary artery surgery patients?
Answer: Although mean biases between the measurements were low, limits of agreement were too large to provide a clinically acceptable estimation of SvO(2) by ScvO(2) in these conditions. Variations in regional oxygen consumption seem to be the main factor worsening the relationship.

A: no
****
Q: Question: Does frailty predict major bleeding within 30days in elderly patients with Acute Coronary Syndrome?
Answer: Frailty phenotype, as a marker of biological vulnerability, is an independent predictor of major bleeding in elderly patients with ACS. Frailty can play an important role in bleeding risk stratification and objective indices should be integrated into routine initial evaluation of these patients.

A: yes
****
Q: Question: Does leptin play a major role in platelet aggregation in obesity and leptin deficiency?
Answer: Our data show that similar to findings in obese humans, homozygous or heterozygous leptin deficiency is associated with increased platelet aggregation compared with controls, and that higher concentrations of leptin do not increase platelet aggregation.

A:
no
****