This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

[EX Q]: As of 2011, there have been six series — Digimon Adventure, the follow-up sequel Digimon Adventure 02, Digimon Tamers, Digimon Frontier, Digimon Data Squad and Digimon Fusion. The first two series take place in the same fictional universe, but the third, fourth, fifth and sixth each occupy their own unique world. Each series is commonly based on the original storyline but things are added to make them unique. However, in Tamers, the Adventure universe is referred to as a commercial enterprise — a trading card game in Japan, plus a show-within-a-show in the English dub. It also features an appearance by a character from the Adventure universe. In addition, each series has spawned assorted feature films. Digimon still shows popularity, as new card series, video games, and movies are still being produced and released: new card series include Eternal Courage, Hybrid Warriors, Generations, and Operation X; the video game, Digimon Rumble Arena 2; and the previously unreleased movies Revenge of Diaboromon, Runaway Locomon, Battle of Adventurers, and Island of Lost Digimon. In Japan, Digital Monster X-Evolution, the eighth TV movie, was released on January 3, 2005, and on December 23, 2005 at Jump Festa 2006, the fifth series, Digimon Savers was announced for Japan to begin airing after a three-year hiatus of the show. A sixth television series, Digimon Xros Wars, began airing in 2010, and was followed by a second season, which started on October 2, 2011 as a direct sequel to Digimon Xros Wars.
[EX A]: How many series have aired since 2011?

[EX Q]: Managers in the Premier League are involved in the day-to-day running of the team, including the training, team selection, and player acquisition. Their influence varies from club-to-club and is related to the ownership of the club and the relationship of the manager with fans. Managers are required to have a UEFA Pro Licence which is the final coaching qualification available, and follows the completion of the UEFA 'B' and 'A' Licences. The UEFA Pro Licence is required by every person who wishes to manage a club in the Premier League on a permanent basis (i.e. more than 12 weeks – the amount of time an unqualified caretaker manager is allowed to take control). Caretaker appointments are managers that fill the gap between a managerial departure and a new appointment. Several caretaker managers have gone on to secure a permanent managerial post after performing well as a caretaker; examples include Paul Hart at Portsmouth and David Pleat at Tottenham Hotspur.
[EX A]: What are some of the every day tasks that a manager of a team has to deal with?

[EX Q]: By the 1890s the profound effect of adrenal extracts on many different tissue types had been discovered, setting off a search both for the mechanism of chemical signalling and efforts to exploit these observations for the development of new drugs. The blood pressure raising and vasoconstrictive effects of adrenal extracts were of particular interest to surgeons as hemostatic agents and as treatment for shock, and a number of companies developed products based on adrenal extracts containing varying purities of the active substance. In 1897 John Abel of Johns Hopkins University identified the active principle as epinephrine, which he isolated in an impure state as the sulfate salt. Industrial chemist Jokichi Takamine later developed a method for obtaining epinephrine in a pure state, and licensed the technology to Parke Davis. Parke Davis marketed epinephrine under the trade name Adrenalin. Injected epinephrine proved to be especially efficacious for the acute treatment of asthma attacks, and an inhaled version was sold in the United States until 2011 (Primatene Mist). By 1929 epinephrine had been formulated into an inhaler for use in the treatment of nasal congestion.
[EX A]:
Who identified the active substance?