Given scientific fact as input, generate the question from this fact such that it can be answered from the input.

[EX Q]: Induced or spontaneous are the two methods in which mutations arise in dna.
[EX A]: What are the two methods in which mutations arise in dna?

[EX Q]: The values of strangeness assigned to various particles are based on decay systematics.
[EX A]: The values of strangeness assigned to various particles are based on what?

[EX Q]: Acne and different types of cancer can affect skin large organ.
[EX A]:
Acne and different types of cancer can affect what large organ?