In this task, you are given a set of context paragraph and some supporting facts to answer a question. Your task is to generate answer for given question based on set of context paragraphs and supporting facts.

Context_1 : Estrogen (American English) or oestrogen (British English) is the primary female sex hormone as well as a medication. It is responsible for the development and regulation of the female reproductive system and secondary sex characteristics. "Estrogen" may also refer to any substance, natural or synthetic, that mimics the effects of the natural hormone. The estrane steroid estradiol is the most potent and prevalent endogenous estrogen, although several metabolites of estradiol also have estrogenic hormonal activity. Estrogens are used as medications as part of some oral contraceptives, in hormone replacement therapy for postmenopausal, hypogonadal, and transgender women, and in the treatment of certain hormone-sensitive cancers like prostate cancer and breast cancer. They are one of three types of sex hormones, the others being androgens/anabolic steroids like testosterone and progestogens like progesterone. Context_2 : The sex hormone receptors, or sex steroid receptors, are a group of steroid hormone receptors that interact with the sex hormones, the androgens, estrogens, and progestogens. They include the: Context_3 : Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estrone. Levels of estriol in women who are not pregnant are almost undetectable. However, during pregnancy, estriol is synthesized in very high quantities by the placenta and is the most produced estrogen in the body by far, although circulating levels of estriol are similar to those of other estrogens due to a relatively high rate of metabolism and excretion. Relative to estradiol, both estriol and estrone have far weaker activity as estrogens. Although it is less commonly used than other estrogens, estriol is available for medical use throughout the world in a variety of formulations, including for oral and vaginal administration. Context_4 : Estradiol (E2), also spelled oestradiol, is a steroid, an estrogen, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues such as the breasts, uterus, and vagina during puberty, adulthood, and pregnancy, but it also has important effects in many other tissues, including bone, fat, skin, liver, and the brain. While estrogen levels in men are lower compared to those in women, estrogens have essential functions in men, as well. It is found in most vertebrates and crustaceans, insects, fish, and other animal species. Context_5 : Sex steroids, also known as gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors. Their effects are mediated by slow genomic mechanisms through nuclear receptors as well as by fast nongenomic mechanisms through membrane-associated receptors and signaling cascades. The term sex hormone is nearly always synonymous with "sex steroid". The polypeptide hormones luteinizing hormone, follicle-stimulating hormone and gonadotropin-releasing hormone are usually not regarded as sex hormones, although they play major sex-related roles. Context_6 : Female sex tourism is sex tourism by women who travel intending to engage in sexual activities with a sex worker. Female sex tourists may seek aspects of the sexual relationship not shared by their male counterpart, such as perceived romance and intimacy. Women – especially wealthy, single, older white women – plan their holidays to have romance and sex with a companion who knows how to make them feel special and give them attention. The prevalence of female sex tourism is significantly lower than male sex tourism. Context_7 : G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the "GPER" gene. GPER binds to and is activated by the female sex hormone estradiol and is responsible for some of the rapid effects that estradiol has on cells. Context_8 : Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estriol. Estrone, as well as the other estrogens, are synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue. Relative to estradiol, both estrone and estriol have far weaker activity as estrogens. Previously, estrone was available as an injected estrogen for medical use, but it is now no longer marketed. Context_9 : Pregnenolone acetate (brand names Antofin, Previsone, Pregno-Pan), also known as pregn-5-en-3β-ol-20-one 3β-acetate, is a synthetic pregnane steroid and an ester of pregnenolone which is described as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. It has been found to significantly reduce wrinkles in elderly women when applied in the form of a 0.5% topical cream, effects which were suggested to be due to improved hydration of the skin. Pregnenolone acetate has been marketed in France in a topical cream containing 1% pregnenolone acetate and 10% "sex hormone" for the treatment of premature skin aging but was withdrawn from the market in 1992. Although the drug has been described by some sources as a glucocorticoid, other authors have stated that systemic pregnenolone acetate has no undesirable metabolic or toxic effects even at high dosages. Context_10 : Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. Via its indirect action, following an initial surge the production of sex hormones (Androgen and Estrogen) tapers off. fact_1 : Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. fact_2 :  Via its indirect action, following an initial surge the production of sex hormones (Androgen and Estrogen) tapers off. fact_3 : Estrogen (American English) or oestrogen (British English) is the primary female sex hormone as well as a medication. Question: Which female sex hormone, is Deslorelin acetate known to taper off?
Estrogen

Context_1 : Ayatullah Sayyid Muhammad Baqir Al-Mūsawī Al-Muhrī (Arabic: السيد محمد باقر الموسوي المهري‎ ‎ ; also spelled Al-Mohri; 25 December 1948 – 4 July 2015) was a Kuwaiti Ayatullah. He studied in seminaries in Najaf, Iraq under Grand Ayatollah Abul-Qassim Khoei and Mohammad Baqir al-Sadr. Context_2 : `Asabiyya or asabiyyah (Arabic: عصبيّة) refers to social solidarity with an emphasis on unity, group consciousness and sense of shared purpose, and social cohesion, originally in a context of "tribalism" and "clanism". It was a familiar term in the pre-Islamic era, but became popularized in Ibn Khaldun's "Muqaddimah" where it is described as the fundamental bond of human society and the basic motive force of history. `Asabiyya is neither necessarily nomadic nor based on blood relations; rather, it resembles philosophy of classical republicanism. In the modern period, the term is generally analogous to solidarity. However, it is often negatively associated because it can sometimes suggest loyalty to one's group regardless of circumstances, or partisanship. Ibn Khaldun also argued that `asabiyya is cyclical and directly related to the rise and fall of civilizations: it is most strong at the start of a civilization, declines as the civilization advances, and then another more compelling ʿasabiyyah eventually takes its place to help establish a different civilization. Context_3 : The Sha'baniyah Munajat (Persian: مناجات شعبانیه‎ ‎ ) is a supplication attributed to Ali ibn Abi Talib, the first Shia Imam, that invoked in the Sha'ban month. The supplication was narrated by Ibn Khalawayh and is mentioned by Abbas Qumi in Mafatih al-Janan, Sayyed Ibn Tawus in Eqbal al-a’mal, and Muhammad Baqir Majlesi in Bihar al-Anwar. In the Mafatih al-Janan, the Munajat mentioned at Sha'ban month prayers section. This supplication known as a monologue of Ali ibn Abi Talib with his God, Allah. In the supplication, Ali emphasizes on God's generosity and called Allah as creator and infinite of human. Ali advised to recite the Du'a with presence of heart. Context_4 : Muhammad Baqir ibn Muhammad Akmal al-Wahid Bihbahani, also Vahid Behbahani, or also Waheed Behbahani (1706–1791), was a Twelver Shia Islamic scholar. He is widely regarded as the founder or restorer of the "Usuli" school of Twelver Shi'a Islam and as playing a vital role in narrowing the field of orthodoxy in Twelver Shi'a Islam by expanding "the threat of "takfir"" against opposing scholars "into the central field of theology and jurisprudence". Context_5 : Muhammad Baqir Yazdi was an Iranian mathematician who lived in the 16th century. He gave the pair of amicable numbers 9,363,584 and 9,437,056 many years before Euler's contribution to amicable numbers. He was the last notable Islamic mathematician. His major book is "Oyoun Alhesab" (Arabic:عيون الحساب). Context_6 : Azad was born in Delhi in a highly educated Persian immigrant family. His mother died when he was four years old. His father, Muhammad Baqir (c.1810-1857), was educated at the newly founded Delhi College. His father Muhammad Baqir died by the punishment or summoned from the court because of his favour with Muslims. Besides his many other activities he worked in the British administration. In early 1837, Muhammad Baqir bought a press and launched the "Delhi Context_7 : He completed his studies in Mashhad, Qom and Najaf were sought and was awarded the degree of Ijtihad. Muhammad Baqir Rizvi Madras, Mirza Javad Maleki Tabrizi, Sheikh Ali Shah Abadi and Abdul-Karim Ha'eri Yazdi, Abu al-Hasan Isfahani, Muhammad Hosein NĀʾĪNĪ and Sheikh Ziauddin Iraqi were his professors." Context_8 : The Muqaddimah, also known as the Muqaddimah of Ibn Khaldun (Arabic: مقدّمة ابن خلدون‎ ‎ ) or Ibn Khaldun's Prolegomena (Ancient Greek: Προλεγόμενα ), is a book written by the Arab historian Ibn Khaldun in 1377 which records an early view of universal history. Some modern thinkers view it as the first work dealing with the philosophy of history or the social sciences of sociology, demography, historiography, cultural history, social Darwinism, ecology, Darwinism and economics. The "Muqaddimah" also deals with Islamic theology, political theory and the natural sciences of biology and chemistry. Context_9 : Ibn Khaldun ( ; Arabic: أبو زيد عبد الرحمن بن محمد بن خلدون الحضرمي‎ ‎ , "Abū Zayd ‘Abd ar-Raḥmān ibn Muḥammad ibn Khaldūn al-Ḥaḍramī" ; 27 May 1332 – 17 March 1406) was a North African Arab historiographer and historian. Context_10 : Du'a Nudba is one of the major Shiite prayers about Muhammad al-Mahdi and his occultation. Nudba means to cry and Shiites read the prayer for ask to help them during the occultation. The supplication recite in Eid al-Fitr, Eid al-Adha, Eid al-Ghadeer, and in every Friday morning. Mazar al-Kabir, Mazar al-Ghadim, and Mesbaho al-Zaer were narrated the supplication. These books were written with authentic narrators such as Sayyed Ibn Tawus. Muhammad Baqir Majlisi wrote this prayer in Zaad-ul-Maad from Imam Ja'far al-Sadiq. Also, Albazofari, a person who lived in minor occultation, narrated from The Four Deputies of Imam Mahdi that Imam Mahdi said to read the prayer. fact_1 : Muhammad Baqir Yazdi was an Iranian mathematician who lived in the 16th century. fact_2 : Ibn Khaldun ( ; Arabic: أبو زيد عبد الرحمن بن محمد بن خلدون الحضرمي‎ ‎ , "Abū Zayd ‘Abd ar-Raḥmān ibn Muḥammad ibn Khaldūn al-Ḥaḍramī" ; 27 May 1332 – 17 March 1406) was a North African Arab historiographer and historian. Question: Who lived earlier, Ibn Khaldun or Muhammad Baqir Yazdi?
Ibn Khaldun

Context_1 : Crimson Skies is an arcade flight video game developed by Zipper Interactive and published in 2000 by Microsoft Game Studios. Although a flight-based game, "Crimson Skies" is not a genuine flight simulator, as the game is based less on flight mechanics than on action. According to series creator Jordan Weisman, "Crimson Skies" is "not about simulating reality—it's about fulfilling fantasies." Context_2 : Ace Combat (エースコンバット; "Ēsu Konbatto" ) is a hybrid flight simulation action video game series featuring 18 games published by the Japanese company Bandai Namco Games and produced by Project Aces, an internal development team. The series emphasizes fast-paced action and dramatic plots, and has established itself as one of the longest running arcade flight action franchises. Context_3 : Ace Combat: Assault Horizon (エースコンバット アサルト・ホライゾン , Ēsu Konbatto Asaruto Horaizon ) is an installment of the "Ace Combat" arcade combat flight video game series. It was developed by Project Aces and published by Namco Bandai Games for the PlayStation 3 and Xbox 360 platforms in October 2011. The game was later released on Microsoft Windows in January 2013 through Steam. Context_4 : Ace Combat: Joint Assault , or Ace Combat X²: Joint Assault in Japan, is a 2010 3D arcade, combat flight video game developed by Access Games and published by Namco Bandai Games for the PlayStation Portable. It is the second in the series released for the PlayStation Portable and the fourth for a portable platform. It is also the first game in the Ace Combat franchise to be set in the real world. The game was released on August 26, 2010 in Japan, on August 31, in North America, and in Europe on September 24. Context_5 : Crimson Skies: High Road to Revenge is a first-party video game developed by FASA Studio (part of Microsoft Game Studios) for the Xbox. The game, like the earlier "Crimson Skies" for the PC, is an action-oriented arcade flight game. Nonetheless, there are significant differences between the gameplay of "High Road to Revenge" and that of the original PC title. For example, while the Xbox game has a more open-ended mission structure, it offers less plane customization than the PC game. Context_6 : Tom Clancy's H.A.W.X is a 2009 arcade flight video game developed by Ubisoft Bucharest and published by Ubisoft for Microsoft Windows, Xbox 360 and PlayStation 3, and by Gameloft for BlackBerry PlayBook, iOS, Palm Pre, Android and Symbian^3. It was released for Xbox and PlayStation in North America on March 3, 2009, for Windows on March 17, for iOS on December 9, for BlackBerry on January 8, 2010, for Palm Pre on April 2, for Android on September 13, and for Symbian on January 16, 2011. A Wii version was announced, but was ultimately canceled. In September 2010, a sequel titled "Tom Clancy's H.A.W.X 2" was released for Xbox 360 and PlayStation 3. The Microsoft Windows and Wii versions were released in November 2010. Context_7 : "David Michaels" is a pseudonym for the authors of novels in the "Splinter Cell", "EndWar", "H.A.W.X", and "Ghost Recon" series, all of which were created by Ubisoft Entertainment and developed under Ubisoft's Tom Clancy license. The novel series began as video games for various console systems as well as the PC. As of February 2011, "Michaels" has released six "Splinter Cell" novels, two "EndWar" novels, two "Ghost Recon" novels, and one "H.A.W.X" novel. Context_8 : Ace Combat 7: Skies Unknown is an upcoming action arcade flight video game developed and published by Bandai Namco Entertainment for Microsoft Windows, PlayStation 4, and Xbox One. It is the first "Ace Combat" game developed for an eighth generation console. The PlayStation 4 version will feature exclusive missions for PlayStation VR. Two-player local multiplayer will also be featured. It was revealed at PlayStation Experience 2015 in December 2015. Initially announced only for the PlayStation 4, it was later confirmed to be a multiplatform release in a trailer released in January 2017. The game serves as a sequel to "", and uses Unreal Engine 4. It was initially announced that the game would be released in 2017, but it has since been delayed to 2018. Context_9 : Ace Combat 5: The Unsung War (エースコンバット5 ジ・アンサング・ウォー , Ēsu Konbatto Go Ji Ansangu Wō ) (Ace Combat: Squadron Leader in Europe) is a semi-realistic flight combat video game for the PlayStation 2. Like other titles in Namco's "Ace Combat" series, "Ace Combat 5" features gameplay that is a mix between arcade flight and authentic flight simulation. The game was developed by Project Aces, an internal Namco group credited with the development of the "Ace Combat" series, and was published by Namco in October 2004. A limited number of the games were bundled with the Hori Flightstick 2 accessory. Context_10 : After Burner Climax (アフターバーナー クライマックス ) is a 2006 arcade, combat flight video game developed by Sega AM2 and published by Sega. The game is the sequel to the popular arcade and console "After Burner" games. The game was first released in arcades in 2006 and was later ported to Xbox Live Arcade and PlayStation Network in April 2010. fact_1 : "David Michaels" is a pseudonym for the authors of novels in the "Splinter Cell", "EndWar", "H.A.W.X", and "Ghost Recon" series, all of which were created by Ubisoft Entertainment and developed under Ubisoft's Tom Clancy license. fact_2 : Tom Clancy's H.A.W.X is a 2009 arcade flight video game developed by Ubisoft Bucharest and published by Ubisoft for Microsoft Windows, Xbox 360 and PlayStation 3, and by Gameloft for BlackBerry PlayBook, iOS, Palm Pre, Android and Symbian^3. Question: What author who created an arcade flight video game is a pseudonym?

David Michaels