Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

[EX Q]: Paragraph: “The water affects everyone,” she said, which is why she believes her job is so important. Reese is studying public health and environmental health at East Carolina University in North Carolina. She will be an intern for the East Shore department, working on the Connecticut shoreline until the end of July. Reese spends her Tuesday mornings driving around to all the public and private natural swimming areas in Branford, North Branford and East Haven, collecting water samples and putting them on ice in her purple cooler. The samples are then collected by state Department of Public Health couriers and brought to the state lab in Rocky Hill for testing. Water quality testing has always been a priority for the East Shore department every summer, but this year, Alex Cinotti, the assistant director of health, has something he’s trying to prove. Every year, from Memorial Day to Labor Day, the department collects weekly water samples from 12 water bodies used for swimming, both freshwater and saltwater, to ensure bacteria levels are low enough for public safety. Samples are collected and tested once a week, and as long as bacteria levels fall below state-determined risk levels, the beaches and other water bodies remain open. This year, however, Cinotti would like to take the sampling a step further — to show a direct correlation between rainfall and elevated bacteria levels, he said, as rain will often wash contaminants into public waters and cause bacteria levels to rise. “This is our opportunity to take samples and establish a pattern,” Cinotti said. “Bacteria is bacteria and we consider it pathogenic.” As such, in addition to the weekly sampling of water, Cinotti said that the department is collecting samples after heavy rains to see if bacteria levels rise after rainfall. This kind of analysis could not be done last summer, Cinotti said, because there were few rain events due to the drought. On the state level, the Department of Energy and Environmental Protection will close public beaches after a significant amount of rainfall, in anticipation of potentially higher bacteria levels. Scott Szalkiewicz, a health program supervisor for the state Health Department, told the Register last summer that because samples take 24 hours to process, it’s helpful to be able to close beaches before test results come in when officials believe bacteria levels will be high based on the amount of rain and visual indicators. The East Shore District Health Department serves Branford, North Branford and East Haven. The 12 bathing waters surveyed each week include the east and west East Haven beaches, the Clark Avenue beach, Branford Point, Stony Creek, Hotchkiss Grove, Turtle Bay, Sunrise Cove, Lanphier Cove, Cedar Lake, Linsley Lake and Clear Lake. According to water quality records from the East Shore District Health Department in 2016, there was only one time when bacteria levels reached a level at which one of the beaches had to close. Sunrise Cove reached a level of 1,000 colonies of bacteria in the sample of 100 milliliters of water on Aug. 2, 2016, according to the records. Cinotti said that the safe levels for salt water are 104 colonies of bacteria per 100 milliliters of water and 235 colonies for fresh water per 100 milliliters of water. Some things that cause heightened bacteria levels include wild animal and dog feces, sewer overflows and leaks, Cinotti said. Rain may wash contaminants such as sewer overflows, nitrogen-rich pollutants and goose and dog feces into the Sound and other bathing water bodies. Potential health risks from swimming in water with high levels of bacteria include possible infections to open wounds and gastrointestinal illness when water is accidentally swallowed, Cinotti said. He added that it’s possible swimmers could contract eye- or ear-related illnesses from high levels of bacteria. “We really need to protect children,” Cinotti said. “They are more vulnerable than adults.” ___ Online: http://bit.ly/2rFTp4s ___ Information from: New Haven Register, http://www.nhregister.com Claim: Officials study link between rain and bacteria in water.
[EX A]: For Kellyn Reese, waking up on Tuesday mornings and going to the beach because it’s her job is a nice perk of being a summer intern at the East Shore District Health Department.

[EX Q]: Paragraph: The trial results on patients with a gene anomaly known as NTRK fusion, which occurs in less than 1 percent across a range of tumor types, were presented at the annual congress of the European Society for Medical Oncology (ESMO) in Munich on Sunday. Germany’s Bayer and U.S. partner Loxo, in turn, released data for their rival compound larotrectinib, which slightly improved on previous high-efficacy readings in an enlarged trial. Traditionally, oncologists have made treatment decisions based on where in the body a tumor started, increasingly helped by the growing knowledge of cancer’s complex genetic drivers. Under the tumor-agnostic approach, also known as pan-tumor, drugmakers skip the organ-of-origin perspective and regroup patients based only on signature genetic mutations, but success in real life will depend on the fast spread of comprehensive gene-sequencing tools for tissue samples. Individually, the mutations are so rare that cancer units are seen as unlikely to run dedicated tests for each. Roche’s Foundation Medicine supplies the comprehensive kits, competing with Thermo Fisher Scientific and Caris Life Sciences. “It’s one of the reasons we acquired Foundation Medicine, to make this comprehensive genomic profiling routine and upfront in the course of the disease,” said Daniel O’Day, the head of Roche’s Pharmaceuticals division. Loxo’s larotrectinib pill, co-developed with Bayer, was last year shown to shrink tumors in 75 percent of patients with the NTRK fusion gene anomaly, occurring in the lung, pancreas, or more than a dozen other organs. On Sunday, the response rate to larotrectinib within an enlarged group of 122 trial participants - up from 55 initially and now spanning 24 tumor types - was shown to be 81 percent. Roche said the readings from the two NTRK fusion trials were not comparable because they are made up of different patient types. Loxo’s study, for instance, included some cancers in children, while Roche plans to investigate those separately. The Roche compound is designed to tackle several oncogenic mutations and last month, it unveiled data here on entrectinib pushing back tumors in 77 percent of lung cancer patients with a mutation called ROS1. Merck & Co’s Keytruda in May last year became the first drug to win approval for pan-tumor use, though that remains a relatively small market for the mega-selling drug. Bayer and Loxo are testing a second pan-tumor drug, LOXO-195. Roche Pharmaceutical’s O’Day welcomed a wider field. “Both things have to happen: You need genomic profiling and you need enough targeted medicines to encourage physicians to make that diagnosis upfront very complete. This is the world we’re entering,” he said. Though response rates could encourage a race for more such drugs, the need for suitable gene mutations or fusions will be a tall order, said oncologist Ulrik Lassen of Copenhagen’s Rigshospitalet, who co-authored the larotrectinib study. “You need to screen a lot of patients to find the needle in the haystack and the method is complicated, costly and time-consuming. When we get better at using these technologies, we can find more oncogenic fusions and companies will be smart enough to find the agents that target them.”  Roche acquired entrectinib as part of its takeover deal with U.S. cancer drug specialist Ignyta Inc for $1.7 billion, agreed in December last year. Immuno-oncology remains another major business area for Roche, which also released positive results on using its Tecentriq drug in a group of breast cancer patients with a particularly poor prognosis. Claim: Roche takes on Loxo, Bayer in gene-defined cancer class.
[EX A]: Roche’s entrectinib cancer pill was shown to shrink tumors in 57 percent of patients within a group that can only be identified via genetic profiling, as the Swiss drugmaker challenges an alliance of Bayer and Loxo Oncology in a new targeted treatment area.

[EX Q]: Paragraph: The Ontario government is investigating a hog farm in the province’s Middlesex County after a laboratory finding of the virus, Dr. Greg Douglas, chief veterinary officer for Ontario, said at a news conference. Middlesex County is in southern Ontario near the city of London. Separately, one of Canada’s biggest pork processors, Olymel LP, said tests also confirmed the virus at an unloading dock of its Saint-Esprit slaughter facility northeast of Montreal, Quebec. “What they have found in the U.S. is this virus is highly contagious,” Douglas said. “It has been very difficult for producers to absolutely mitigate the threat.”  PEDv - which causes diarrhea, vomiting and severe dehydration in hogs - has turned up in 23 of the 50 states since its discovery in the United States last April. The virus, which is already established in Europe and Asia, poses no threat to humans and is not a food safety risk, according to the Canadian Swine Health Board. Canada is the world’s third-largest pork shipper. There are no official figures for pigs lost to the disease, but U.S. hog industry analysts estimate 1 million to 4 million have died. The virus continues to spread in the United States, with a total of 2,394 confirmed cases in 23 states as of the week ended January 18, according to the U.S. Department of Agriculture’s National Animal Health Laboratory Network (NAHLN). As defined by the USDA, each diagnostic case could represent multiple animals at either a single farm site or several locations. An undisclosed number of pigs have died at the Ontario farm. Douglas said the farm is not under quarantine, but the farmer has agreed not to move pigs off it in the near term. Quebec and Ontario are Canada’s two biggest hog-producing provinces. Canadian hog farmers have been on high alert since the virus reached the United States last year, taking additional biosecurity measures such as washing out trucks returning from south of the border. But the spread to Canada was seen as just a matter of time. The virus can spread through contaminated pig feces on pigs, trucks, boots and clothing. Olymel spokesman Richard Vigneault said that, as a result of extra testing, the PED virus was discovered on Tuesday at the Quebec slaughter plant. The confirmed case did not affect production, he said in an interview with Reuters. PEDv has no known implications for international pork trade, said Martin Rice, executive director of the Canadian Pork Council. In June, however, Mexico restricted imports of live hogs from the United States because of the deadly virus. Claim: Pig-killing PEDv virus moves into Canada.
[EX A]:
Canada has discovered its first two cases of the Porcine Epidemic Diarrhea virus (PEDv), which has already killed more than 1 million pigs in the United States, government and industry officials said on Thursday.