Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Example Input: Paragraph: Such a test could initially be used to select patients for clinical trials of experimental treatments being developed to try to halt progression of Alzheimer’s, the researchers said, and may one day move into routine use in doctors’ clinics. “Alzheimer’s begins to affect the brain many years before patients are diagnosed (and) many of our drug trials fail because by the time patients are given the drugs the brain has already been too severely affected,” said Simon Lovestone of Oxford University, who led this work from King’s College London. “A simple blood test could help us identify patients at a much earlier stage to take part in new trials and hopefully develop treatments,” he said. Alzheimer’s is the most common form of dementia, a brain-wasting disease which in 2010 was estimated to be costing the world $604 billion a year. The fatal disease affects 44 million people worldwide, with the number set to triple by 2050, the campaign group Alzheimer’s Disease International says. Several big pharma firms including Roche, Eli Lilly, Merck & Co and Johnson & Johnson, are pursuing various approaches to get to the root cause of Alzheimer’s and try to find treatments to halt its progression. Yet over the past 15 years, more than 100 experimental Alzheimer’s drugs have failed in trial. Lovestone and other experts believe this may be because drug trials are conducted too late, in patients whose condition has already gone too far. A predictive test for use before people develop symptoms would help researchers select the right people for drug trials, and help show whether the experimental drugs are working. Previous studies have found that PET brain scans and tests of lumbar fluid can be used to predict the onset of dementia from people with a less severe condition known as mild cognitive impairment (MCI), but these tests are expensive and invasive, so scientists are keen to develop a cheaper, simpler blood test. MCI includes problems with day-to-day memory, language and attention. It can be an early sign of dementia, or a symptom of stress or anxiety. Around 10 percent of people diagnosed with MCI develop dementia within a year. Apart from regular assessments to measure memory decline, there is currently no accurate way of predicting who will or won’t develop dementia. For this study, published in the journal Alzheimer’s & Dementia, Lovestone’s team used blood samples from 1,148 people - 476 with Alzheimer’s, 220 with mild cognitive impairment and 452 elderly controls without dementia. They were analyzed for 26 proteins previously found to be linked with Alzheimer’s. The team found 16 of these 26 proteins to be strongly associated with brain shrinkage in either MCI or Alzheimer’s and then ran a second series of tests to see which of these could predict which patients would progress from MCI to Alzheimer’s. With this second series, they found a combination of 10 proteins capable of predicting with 87 percent accuracy whether people with MCI would develop Alzheimer’s disease within a year. Experts in the field welcomed the results but said they should be replicated in larger studies before an Alzheimer’s blood test could be rolled out for use in doctors’ clinics. “The results reported today are interesting, but as the authors point out there is still a very large amount of work remaining until a usable blood test for Alzheimer’s disease becomes available,” said Adrian Pini of the MRC Center for Developmental Neurobiology at King’s College London. James Pickett, head of research at the Alzheimer’s Society, said the research “does not mean that a blood test for dementia is just around the corner”. “These 10 proteins can predict conversion to dementia with less than 90 percent accuracy, meaning one in 10 people would get an incorrect result,” he said. “Accuracy would need to be improved before it could be a useful diagnostic test.” Claim: Study paves the way for a blood test to predict Alzheimer's.
Example Output: British scientists have identified a set of 10 proteins in the blood that can predict the onset of Alzheimer’s and call this an important step towards developing a test for the incurable brain-wasting disease.

Example Input: Paragraph: Now the ranking Democrat on the Senate Commerce, Science and Transportation Committee is questioning the role played by nominee Nancy Beck in the decision to shelve the guidelines. Beck is not a medical doctor and has no background in virology. President Donald Trump has nominated Beck to be chairwoman and commissioner of the U.S. Consumer Product Safety Commission, a position that requires Senate confirmation. Beck is scheduled to appear before the Senate committee later this month. Emails obtained by The Associated Press show that Beck was the U.S. Centers for Disease Control and Prevention’s main point of contact in the White House about the proposed recommendations. At issue was a 63-page guide created by the CDC that would give community leaders step-by-step instructions for reopening schools, day care centers, restaurants and other facilities. Beck is currently on detail for the White House with the Office of Management and Budget, where she is coordinating review of pandemic-related stimulus measures, and of the CDC guidance. She has a doctorate in environmental health and has worked as a toxicologist, specializing in the study of the health risks from chemical substances to the human body. “I am deeply concerned by the nominee’s involvement in advocating for the deregulation of toxic chemicals known as PFAS and I also have questions about her potential involvement with the CDC coronavirus guidance,” said Sen. Maria Cantwell, the top Democrat on the committee, in a statement to AP. Cantwell sent a letter of inquiry on Wednesday to Beck, asking for more information. Beck did not immediately respond to questions from AP sent to her via email. Beck’s role in the coronavirus guidance document was revealed in a series of emails from late April obtained by the AP. On April 10, CDC Director Robert Redfield emailed the guidance to a group that included some of the president’s closest White House advisers, including Trump son-in-law Jared Kushner, and counselor Kellyanne Conway, and Dr. Anthony Fauci, the government’s top infectious disease expert. Redfield wrote that he wanted White House review and clearance to post the documents on the CDC website. By the time the administration had released its “Opening Up America Again” plan on April 17, the process had stalled. The emails show that the CDC’s chief of staff, Robert “Kyle” McGowan, emailed Beck on April 26 seeking an update. “We need them as soon as possible so that we can get them posted,” McGowan wrote. Beck responded that they still needed approval. “WH principals are in touch with the task force so the task force should be aware of status.” The next day McGowan checked with Beck again. “I have no word on revisions yet for the rest of the package. My understanding is it is still being reviewed,” she responded. One of Beck’s colleagues, Satya P. Thallam, followed up saying the White House Principal’s Committee had not yet responded. “However, I am passing along their message: they have given strict and explicit direction that these documents are not yet cleared and cannot go out as of right now — this includes related press statements or other communications that may preview content or timing of guidances.” McGowan responded that White House changes would cause further delay. “The comments and edits we get back will have to be reviewed at the CDC for scientific accuracy,” McGowan responded to Thallam and Beck. “We will not be able to post the document we get back from the WH quickly if there are a substantial number of edits.” On April 30, one day before Trump’s May 1 reopening goal, McGowan was told guidelines will “never see the light of day,” according to three sources inside CDC who were not authorized to publicly discuss the matter and spoke on condition of anonymity. In her letter, Cantwell said the emails raise “serious questions about whether you believe in preserving and respecting the scientific and professional integrity of scientists and health professionals that work at agencies like the CDC and the CPSC.” On Thursday, another committee Democrat cited AP’s story in calling on the administration to withdraw Beck’s nomination. “Nancy Beck reportedly led efforts to thwart CDC’s science-based guidance for protecting public health — exactly the wrong credential for a nominee to lead the CPSC, and clear reason her nomination should be withdrawn,” said Sen. Richard Blumenthal, D-Conn.  An OMB spokesperson said the initial submission to the office was the “start of the deliberative process, not the end, and everyone knows that,” and added the White House appreciated that Beck continued “serving her country by helping the government respond to this pandemic while her nomination was pending.” Before joining the Trump administration, Beck was a senior director for policy at the American Chemistry Council, the primary lobbying arm for U.S. chemical manufacturers. In that role, she frequently testified on Capitol Hill against stricter safeguards to protect human health and the environment from toxins. In 2017, she joined the Environmental Protection Agency as a top official in the Office of Chemical Safety and Pollution Prevention. She oversaw efforts to block or weaken Obama-era regulations on harmful substances including asbestos, and at the White House was involved in a rewrite of limits on PFAS. Those are class of chemicals used in making nonstick cooking pans and raincoats, and the chemicals have been linked to birth defects. Democrats and environmentalists have opposed her nomination to lead the consumer agency. While she awaits Senate confirmation, Beck has been assigned to the White House Council of Economic Advisers, which consults with the president on matters of economic policy. On May 7, the day AP ran a story about the administration shelving the guidance, McGowan emailed Beck and copied Redfield. “When can we expect OMB comments on the rest of the guidance? We would really like to get these moving,” he wrote. Late that afternoon, the White House called the CDC and told the agency to resend a series of detailed “decision trees” that had been shelved. Emails showed staff working on the guidance said they would “stand down.” At a Senate hearing Tuesday on the coronavirus, Sen. Chris Murphy, D-Conn., asked Redfield about the status of that guidance. Redfield replied: “Soon.” ___ Dearen reported from Gainesville, Florida. Associated Press writer Zeke Miller contributed to this report. ___ Follow AP investigative reporters Jason Dearen at http://twitter.com/JHDearen and Michael Biesecker at http://twitter.com/mbieseck Claim: Emails: Trump nominee involved in shelving CDC virus guide.
Example Output: A former chemical industry executive nominated to be the nation’s top consumer safety watchdog was involved in sidelining detailed guidelines to help communities reopen during the coronavirus pandemic, internal government emails show.

Example Input: Paragraph: "Gail Collins loves telling the story of how Mitt Romney drove his family to Canada with the family dog strapped to the roof of the car -- and telling it, and telling it, and telling it. The liberal New York Times columnist has mentioned the incident in print 19 times, by our count. She devoted a column to the incident in 2007 when Romney first ran for president. In another column, she suggested John McCain pick Romney for his running mate ""so I can repeatedly revisit the time Mitt drove to Canada with the family dog on the station-wagon roof."" And when Sarah Palin was picked instead, and Collins opined that ""unlike Mitt Romney, she has never gone on vacation with the family dog strapped to the roof of the car."" Collins regularly includes the incident in jocular news quizzes she writes. (A typical question: Which Republican hopeful ""continued to fail to explain why he drove to Canada with the family dog strapped to the roof of the car?"" Mitt Romney.) She complained that his 2010 campaign book No Apology didn't mention it, calling it ""a critical oversight."" Last year, just in time for the holidays, she suggested someone make ""a tasteful Mitt Romney Christmas Ornament"" depicting the scene of the dog on the roof. And just last week, she noted that the issue wasn't discussed during the Republican debate at the Ronald Reagan Library. Romney's top rival, Texas Gov. Rick Perry, reportedly shot a coyote that was threatening his daughter's dog, which made the Romney anecdote relevant. ""His puppy-rescue is a stirring picture, especially considering that Perry's chief competitor is the man who drove to Canada with the family dog Seamus strapped to the roof of the car."" Aside from wondering why Collins is so obsessed with the story, we also wondered: Is it true? We reached Collins to ask her why she liked the story so much, but she said she'd rather let her columns speak for themselves. (See a picture of Seamus here.) The story of Seamus the Irish setter is not an Internet rumor. It first appeared in the august pages of the Boston Globe in 2007, when the paper published a seven-part profile of Romney, a former Massachusetts governor who had just launched a presidential run. The story of Seamus kicked off Day Four, a story about Romney's family life, written by Globe reporters Neil Swidey and Stephanie Ebbert. It begins in 1983 with a 36-year-old Mitt Romney carefully packing up his five sons and luggage into the family station wagon for a 12-hour trip from Boston to Ontario, where his parents had a cottage on Lake Huron. At the time, Romney was a successful young consultant with Bain & Company, but he hadn't yet started buying and selling companies with Bain Capital in the private equity field. ""As with most ventures in his life, he had left little to chance, mapping out the route and planning each stop. ... Before beginning the drive, Mitt Romney put Seamus, the family's hulking Irish setter, in a dog carrier and attached it to the station wagon's roof rack. "" Cruel? It's not presented that way in the story, which noted Romney built a special windshield for the carrier, ""to make the ride more comfortable for the dog."" But Seamus must not have been all that comfortable, because he began to experience, um, gastric distress. From the story:   As the oldest son, Tagg Romney commandeered the way-back of the wagon, keeping his eyes fixed out the rear window, where he glimpsed the first sign of trouble. ''Dad!'' he yelled. ''Gross!'' A brown liquid was dripping down the back window, payback from an Irish setter who'd been riding on the roof in the wind for hours. As the rest of the boys joined in the howls of disgust, Romney coolly pulled off the highway and into a service station. There, he borrowed a hose, washed down Seamus and the car, then hopped back onto the highway. It was a tiny preview of a trait he would grow famous for in business: emotion-free crisis management. As the story quickly made its way around the Internet, Romney loathers -- and dog lovers -- had a field day. The liberal blog Wonkette said it showed Romney would be a great commander-in-chief for the notorious Iraq prison Abu Ghraib. David Kravitz of the liberal blog Blue Mass Group called it ""nuts"" and ""classic Romney: it solves a problem efficiently, in a business-like manner, and with no regard whatsoever for the suffering that the solution may cause."" Ingrid Newkirk of People for the Ethical Treatment of Animals told Time's Ana Marie Cox that Romney was giving his children ""a lesson in cruelty"" and that dogs under extreme stress might lose control of their bowels. ""That alone should have been sufficient indication that the dog was, basically, being tortured,"" she said. Cox explored whether Romney's actions might have been illegal under animal cruelty laws. (A moot point, because the statute of limitations has long expired.) As to the accuracy of the story, the Globe learned of the incident from friends of the family and confirmed the details with the Romney family. And the candidate himself didn't dispute the report. In fact, in the days following, he defended it. Seamus loved riding in the carrier, Romney told reporters on the campaign trail in 2007. ""He scrambled up there every time we went on trips,"" Romney said. ""He got (up) all by himself and enjoyed it."" He also said PETA had targeted him because there was a rodeo at the 2002 Salt Lake City Olympics, and because he went quail hunting in Georgia. ""And they're not happy that my dog likes fresh air,"" he added. Actually, Seamus had been dead -- of natural, non-station wagon-related causes -- for years when the story appeared. (He had retired to California to live with Romney's sister, who had more space.) We didn't get answers about Seamus from the Romney campaign, but from Neil Swidey, the Boston Globe reporter who unearthed the story. Swidey said he chose the incident to begin his story because he thought it would resonate with readers as an illustration of Romney's approach to solving problems -- trip is interrupted by dog poop, so Romney pulls over, borrows a hose, takes care of the problem, and is back on his way. ""I certainly didn't write it to make it the basis on which you judge a presidential candidate. The fact that some people appear to be doing that is a little bit crazy. But I can understand why it resonates with people,"" Swidey said. ""It's a window into how this guy operates."" Swidey said some people see it as evidence of Romney's heartlessness, while others see him as logical man and a problem solver. He confirmed the impression we got from reading the story, that the incident was amusing family lore, and that none of the Romney family was upset or disturbed by the dog riding on the roof. In fact, some of the Romneys said they thought the dog actually liked riding on the roof. (Finally, lest we be accused of utter frivolousness, we asked Swidey what aspects of Romney's biography might be more relevant to voters considering Romney for president. He pointed us toward the Globe's coverage of Romney's business career in private equity, his time as governor and Romney's relationship with his father George, who ran for president himself back in 1968.) Here, we're ruling on Collins' statement that Romney ""drove to Canada with the family dog Seamus strapped to the roof of the car."" It's important to note that the dog was not literally strapped to the car, as in tied around its midsection. Rather, Seamus was in a carrier with a protective windscreen that Romney had built. The dog's diarrhea might indicate that something was amiss, but Romney's family didn't seem bothered by it. The anecdote is presented in the Globe as funny family story, not as evidence of Romney's barbaric cruelty." Claim: "Mitt Romney ""drove to Canada with the family dog Seamus strapped to the roof of the car."
Example Output:
Mitt Romney and the dog on the car roof: one columnist's obsession