Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
Laboratory investigations confirmed a metabolic acidosis (pH 7.15) and hyperchloremia.

Ex Output:
non-adverse drug event


Ex Input:
No explanation for this delay was found, other than the possibility that magnesium sulfate treatment impeded lactogenesis.

Ex Output:
adverse drug event


Ex Input:
We conclude that MB is an effective treatment for ifosfamide-induced encephalopathy.

Ex Output:

adverse drug event