Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Q: Paragraph: We give the story credit for at least citing a $30,000 cost for the “surgeries” but wish it had explained what that included and what it might not. Surgery to change the battery every two years certainly adds to cost. Undoubtedly patients require more intensive expensive followup and perhaps specialized checks to ensure the device is working. With broad strokes across discussion of three different uses for three different conditions, the story did an adequate job quantifiying benefits. As stated in the “Evidence” criterion above, this is where a control group and reporting response rates for treated versus control groups would be very informative. Instead, we only get a qualitative description of benefits which is useful but which might leave careful readers asking for more. This is one area where the story could have been improved. There was no detailed discussion of what can go wrong with deep brain stimulation. There was a brief mention of “if” the electrodes cause neurological side effects. But how often does that happen? And the story noted that the surgery does “sometimes” cause dangerous brain bleeding or infections. How often is “sometimes”? At a very high, overview level, the story explained the current state of the evidence. But more information would have been better. Current evidence for depression/OCD is based on case series. These studies don’t have a control group, making the results more subject to bias. No disease mongering of any of the conditions discussed. The story was repeatedly clear about deep brain stimulation being used when standard medications or behavior therapy had not worked. But it would be helpful to give estimates of the proportion of patients with depression or OCD who aren’t helped by available treatments. Several sources were cited. Dr. Mayberg’s connection to St. Jude Medical was mentioned. The story could have mentioned that Dr. Okun’s center and Dr. Greenberg have received funding from Medtronic. Greenberg’s current funding from the National Institute of Mental Health was noted. We think the sourcing and disclosure was adequate. A strong point of the story was that it repeatedly provided the context for the use of deep brain stimulation — “when standard medications fail…worst-case patients…doesn’t mean patients can abandon traditional therapy…people with intractable (problems)…(people who) failed behavior therapy.” This story already attempted to accomplish a lot, but to be complete, it could have offered explicit description of currently approved options: antidepressant medications (multiple classes); psychotherapy (multiple options); combinations of medications or medications and therapy; transcranial magnetic stimulation (limited availabilty), vagal nerve stimulation, ECT – and estimate of the proportion of patients who fail these treatments. Nonethless, we feel it met the criteria for a satisfactory score. The story states that 70,000 have had deep brian stimulation for Parkinson’s or other movement disorders, and that studies are underway on at least 60 people with intractable obsessive-compulsive disorder and 100 with severe depression. The experimental nature of these approaches is clear from the story. A nice touch would be to give a link to clinicaltrials.gov to allow readers the option of looking up more information on the studies in progress and finding out if recruitment is open and how to access the study. The story did a good job putting the new uses of deep brain stimulation into the context of other research and other therapeutic approaches. It’s clear that the story did not rely on a news release. Claim: Trying brain pacemakers to zap psychiatric disease

A: We especially appreciate the lack of hype in this story. The reporter clearly worked hard to stick to the evidence – not merely to promote the potential. About 65-70 percent of patients with major depressive disorder improve substantially with 1 to 2 course of standard treatment (medication, psychotherapy or combinations). Subsequent treatment options have progressively lower rates of treatment response. Therefore, a significant number of people need other treatment options. Deep brain stimulation is an invasive treatment, but one that has shown promise in a small number of patients.
****
Q: Paragraph: An asthma sufferer wears a paper face mask as she is attended by nurses in this undated file image. REUTERS/Jason Reed The findings were published in the journal Lancet together with two other studies, which found that runny noses and wheezing early on in life may be strong predictors of asthma. In the first study, researchers pored through data provided by parents of more than 205,000 children and found paracetamol use in the first year of life was associated with a 46 percent higher risk of asthma by the time the children were 6 or 7 compared to those never exposed to the drug. Known as acetaminophen in the United States, where it is widely sold under the brand Tylenol, it is used to relieve fever, minor aches and pain, and is used in a liquid suspension for children. Medium use of paracetamol in the past 12 months increased asthma risk by 61 percent, while high dosages of once a month or more in the past year raised the risk by over three times. Medium use was defined as once per year or more, but less than once a month. Suspicions of a possible link between paracetamol and asthma emerged in recent years when experts observed an increased use of the drug to a simultaneous rise in asthma prevalence worldwide. One theory is that paracetamol reduces antioxidants in the body. Some experts think antioxidants, which stop unstable molecules known as free radicals from doing too much damage, can lower the risk of cancer, heart disease and other ailments. “Paracetamol can reduce antioxidant levels and ... that can give oxidative stress in the lungs and cause asthma,” one of the researchers, Richard Beasley at the Medical Research Institute of New Zealand, told Reuters in a telephone interview. As with asthma, monthly use of paracetamol doubled the risk of eczema and trebled that of rhinoconjunctivitis — repetitive sneezing, rhinorrhea, nasal congestion and hay fever — by the time children were 6 or 7, the study found. However, the researchers stressed paracetamol should remain the preferred drug to relieve pain and fever in children because its alternative, aspirin, was linked to the risk of Reye’s syndrome, a rare but serious complication in children. “The findings do lend support to the current guidelines of the World Health Organization, which recommend that paracetamol should not be used routinely, but should be reserved for children with a high fever (38.5 Celsius or above),” they wrote. Another study in The Lancet found that rhinitis, or hay fever and other allergic reactions causing a runny nose, was a strong predictor of asthma that develops in adulthood. Researchers monitored 6,461 people in 14 countries who were free of asthma at the start of study for more than 8 years. Those who suffered rhinitis and were allergic to an assortment of agents like house dust mites, cat, grass and birch were 3.5 times more likely to develop asthma later on compared to those who suffered no allergies nor rhinitis. The third study in Arizona in the United States found wheezing early in life may be an ominous sign of asthma developing in adulthood. Researchers pored through data on 849 people going back 22 years to the time they were babies. Of 181 cases of active asthma, 49 were newly diagnosed, of which 35 were women. “In over 70 percent of people with current asthma and 63 percent of those with newly diagnosed asthma at age 22 years, episodes of wheezing had happened in the first three years of life or were reported by parents at age six years,” wrote the researchers at the Arizona Respiratory Center. In an accompanying comment, Suzanne Lau of Charite University Medicine in Germany, wrote: “These findings identify a population at risk of chronic obstructive airway disease in early adulthood, and they already showed a predisposition during preschool years.” Lau was not involved in the study. Claim: Paracetamol use may raise asthma risk in children.

A: Infants who have been given the common pain reliever paracetamol may have a higher risk of developing asthma and eczema by the time they are 6 or 7, a large study covering children in 31 countries has found.
****
Q: Paragraph: Roy treads carefully as the water rises to his knees, seeming for a moment to lose sight of his prey. Then in one swift action he steps back, takes aim and shatters the outback calm, and a crocodile, with a single booming shotgun blast. I am definitely not in Sydney anymore. For more than 10 years I have dreamed of photographing the daily lives of Aboriginal Australians in the northern-most tip of the Northern Territory, Australia’s rugged “Top End”. Their Arnhem Land reserve - closer to Bali than Sydney - covers an area of around 97,000 sq km (37,500 sq miles), has a population of around 16,000 and access for non-Aborigines is by invitation only. Australia’s Aborigines are the custodians of the longest unbroken cultural tradition on Earth, having migrated Down Under from Africa via Asia between 40,000 and 60,000 years ago, and connection to the land is practically written into their DNA. But the arrival of European settlers in the 18th century marked the beginning of a painful disenfranchisement. Massacres are still tearfully remembered and today the majority of Aborigines live in abject poverty. Last year, while on patrol with the Indigenous Australian Army unit known as NORFORCE, I met Sergeant Norman Daymirringu, a Yolngu Aborigine, who invited me to go hunting with him near Ramingining, located a bumpy and dusty 600 km drive east of Darwin. Norman is allowed by tradition to share his ancient culture with those he deems worthy, and I was honoured to have been told the Yolngu people’s creation stories and shown their sacred sites. But entering Arnhem Land as a “White Fella” means changing gears and seeing the world through a completely different set of eyes, a great challenge for a photographer. For example, an outsider might struggle to understand a site such as “Dog’s Tongue”, an orange rock amid a barren salt pan, but for Norman it is an integral part of the creation of the universe. The rock has tipped over from its normal position and Norman, as custodian of the land, affords me the rare honor of watching as he puts it back in place, where it has stood for countless millennia. At Yathalamarra, a community consisting of around a dozen houses, we pick up some relatives for the hunt and head on foot to an isolated billabong. With the sun blazing and temperatures reaching 40 degrees Celsius, or 104 Fahrenheit, I am getting pessimistic, when suddenly Roy fires his shotgun. At his feet lies a dead crocodile. Roy pulls the beast from the water, while Marcus keeps lookout. Not far from the shoreline the water starts moving. Suddenly Marcus pounces and, from just beneath the surface, he pulls another crocodile, this one a bleating baby. Roy is nervous about crossing the billabong carrying a heavy dead crocodile, but wanders downstream and grabs a boat hidden in the bushes. Using a stick as a paddle he navigates towards us, throwing the two crocs onto the muddy shore. Wow, its over, I think. We can head off with a great catch and potential feast awaiting. Roy has other ideas: “It’s easier to carry them without all that skin,” he tells me. Any butcher would have been extremely impressed with the skill he showed at filleting this massive beast. The baby was carried out alive. As we are leaving, Roy wraps the intestines in leaves, as nothing that can be eaten is wasted, and he and his sons walk the few kilometers back to the car with crocodile meat and a goanna lizard slung over their shoulders. As for me, I walked away with a unique insight into their culture and some photographs that not many others have had the privilege of taking. Claim: Hunting for pictures, and crocodiles, in remote Aboriginal country.

A:
We are deep in a forest crowded by Australian paperback trees, the air thick with humidity but eerily silent save for the screeching of tropical birds, when Marcus shouts: “Look, crocodiles!”    As a Reuters photojournalist, I’m a trained observer, but I can’t see any crocs. I can’t see anything beyond mud and what little water is left in the small billabong. Aboriginal hunters Marcus and Roy, a father and son team, take off running past a herd of water buffalo and by the time I catch up Roy is standing ankle-deep in murky water, his shotgun pointed at the surface. Hang on a minute: wasn’t your son pointing at crocodiles in that water ten seconds ago? Is this safe?
****