TASK DEFINITION: In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
PROBLEM: Paragraph: Databases and computational tools for mimotopes have been an important part of phage display study. Five special databases and eighteen algorithms, programs and web servers and their applications are reviewed in this paper. Although these bioinformatics resources have been widely used to exclude target-unrelated peptides, characterize small molecules-protein interactions and map protein-protein interactions, a lot of problems are still waiting to be solved. With the improvement of these tools, they are expected to serve the phage display community better. 
 Title: molecules Bioinformatics Resources and Tools for Phage Display

SOLUTION: True

PROBLEM: Paragraph: Background: To our knowledge, no studies to date demonstrate potential spread of microbes during actual emergency medical service (EMS) activities. Our study introduces a novel approach to identification of contributors to EMS environment contamination and development of infection control strategies, using a bacteriophage surrogate for pathogenic organisms. Methods: Bacteriophage FX174 was used to trace cross-contamination and evaluate current disinfection practices and a hydrogen peroxide (H 2 O 2 ) wipe intervention within emergency response vehicles. Prior to EMS calls, 2 surfaces were seeded with FX174. On call completion, EMS vehicle and equipment surfaces were sampled before decontamination, after decontamination per current practices, and after implementation of the intervention. Results: Current decontamination practices did not significantly reduce viral loads on surfaces (P ¼ .3113), but H 2 O 2 wipe intervention did (P ¼ .0065). Bacteriophage spread to 56% (27/48) of sites and was reduced to 54% (26/48) and 40% (19/48) with current decontamination practices and intervention practices, respectively. Conclusion: Results suggest firefighters' hands were the main vehicles of microbial transfer. Current practices were not consistently applied or standardized and minimally reduced prevalence and quantity of microbial contamination on EMS surfaces. Although use of a consistent protocol of H 2 O 2 wipes significantly reduced percent prevalence and concentration of viruses, training and promotion of surface disinfection should be provided. 
 Title: Spread of infectious microbes during emergency medical response

SOLUTION: True

PROBLEM: Paragraph: Coronavirus mouse hepatitis virus (MVH)-A59 causes a persistent, productive infection in primary glial cell cultures . Microbial Pathogenesis 1987 ; 3 : 79-86 . MHV-A59 causes a chronic demyelinating disease in mice which is accompanied by persistence of viral genome in white matter . As part of the investigation into the mechanism of viral persistence, infection of glial cells, probable targets for chronic infection, was studied by the use of mixed glial, enriched oligodendrocyte and enriched astrocyte cultures . Following MHV-A59 infection in vitro, approximately 10% of oligodendrocytes and 30% of astrocytes expressed viral antigens in the absence of overt cytopathic effect . All cultures released infectious virus for the lifetime of the cultures, for at least 45 days in the case of mixed glial cultures . Cultures derived from previously infected mice were similar to those infected in vitro with respect to percentage of cells expressing viral antigen and levels of infectious virus produced . These results show (1) that glial cells are early sites of infection in vivo as well as sites of infection in in vitro cultures, and (2) that glial cells support a non-lytic but productive infection in vitro and thus may contribute to viral persistence in vivo . 
 Title: Coronavirus mouse hepatitis virus (MHV)-A59 causes a persistent, productive infection in primary glial cell cultures

SOLUTION:
True