In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[Q]: Question: The CD40 ligand molecule (CD40L or CD154) is expressed in: 
 Options:  <1> Virgin T lymphocytes. <2> Activated T lymphocytes <3> NK lymphocytes. <4> Virgin B lymphocytes. <5> B activated lymphocytes.
[A]: 2


[Q]: Question: A drug with a seemingly monocompartmental distribution pattern is administered in the form of i.v. perfusion. at a constant speed of 20 mg / h for 48 h. Once the perfusion is finished, three blood samples are taken, which, when analyzed, allow the calculation of the primary parameters of the model Kel = 0.0495 h-1, concentration at the end of the perfusion (C48h) = 5,553 μg / mL, Vd = 66 L. At what time would the steady state be reached ?: 
 Options:  <1> 14 h. <2> 28 h. <3> 42 h. <4> 56 h. <5> 70 h.
[A]: 5


[Q]: Question: Question linked to image nº3 58-year-old liver transplant patient with HCV + cirrhosis. After an uncomplicated postoperative period, the patient is referred to his home. Six weeks after the transplant, he was visited in the outpatient clinic, with a low grade of fever, a worsening of the general condition, a GOT level of 60 IU / L (8-40) and a GPT of 65 IU / L (8-50). with a pattern of marked cholestasis (GGT x 10 and FA x 8) with total bilirubin of 1.7 mg / dL (0.3-1). Likewise, a high number of copies of the HCV was appreciated. It was decided to perform a Doppler ultrasound in which a complete arterial thrombosis was reported. In view of these data, a CT scan and a cholangioresonance were requested, the images of which are presented in the figures. For the clinical, analytical and radiological data, indicate which is the most probable diagnosis of the current problem: 
 Options:  <1> Acute rejection mediated by antibodies with associated arterial thrombosis. <2> Early HCV recurrence. <3> Stenosis of the biliary anastomosis. <4> Extensive ischemic injury of intrahepatic bile ducts. <5> Complete thrombosis of intrahepatic portal branches.
[A]:
4