Given a passage classify if the passage has a definite objective/aim/goal or not. Output '1' if the passage has a defininte objective/aim/goal and output '0' if the passage does not have a definite objective/aim/goal.

[EX Q]: Conflicting results have been reported regarding the predicative roles of alloreactive natural killer (NK) cells on the outcomes of transplantation in leukaemia patients.', 'We prospectively analysed the human leukocyte antigen (HLA) typing of donor-recipient pairs and the KIR typing of the donors in 97 CML patients to address the predictive roles of NK cells in relapse undergoing T-cell-replete haploidentical transplantation.', "Patients with class I ligands for the donor-inhibitory KIR gene exhibited decreased molecular and haematologic relapse rates (P=0.003 and P=0.015, respectively). There was a significantly reduced risk of molecular and haematologic relapse in patients with HLA-C1C2 or C2C2 who accepted donors with KIR2DS1 or in patients with HLA-Bw4 who accepted donors with KIR3DS1 ('recipient with relevant KIR ligand for donor-activating KIR', n=25), compared with the remaining transplants (n=72, P=0.009 and P=0.009, respectively). In addition, the presence of class I ligand in the recipients of donor-activating KIR contributed to a decreased relapse rate in patients lacking class I ligand in the recipient of donor-inhibitory KIR (P=0.04 and P=0.03, respectively).
[EX A]: 0

[EX Q]: Recent research suggests that preintervention functional magnetic resonance imaging (fMRI) data may predict weight loss outcomes among patients who participate in a behavioral weight loss plan. No study has examined whether presurgical brain activation can predict outcomes following bariatric surgery.', 'The aim of the present study was to determine if brain activations during a presurgical fMRI food-motivation paradigm are associated with weight loss 3 and 6 months following laparoscopic adjustable gastric banding (LAGB). Nineteen participants viewed food and nonfood pictures from a well-established food motivation paradigm during an fMRI scanning session before LAGB surgery. Weight was assessed presurgery and 3 and 6 months postsurgery; data for all participants was available at each time point. fMRI data were analyzed using the BrainVoyager QX statistical package. Whole brain voxelwise correlations of presurgery (food-nonfood) brain activation and weight, corrected for multiple comparisons, were performed to analyze the relationship between presurgical brain activation and subsequent weight loss. The settings were a medical university brain imaging center and 2 surgical weight loss centers in a major metropolitan area.', 'Increased activity in frontal regions associated with cognitive control (medial, middle, superior frontal gyrus) and posterior cingulate cortex was associated with weight loss following LAGB.
[EX A]: 0

[EX Q]: Knowledge of sepsis-related end-organ inflammation in\xa0vivo is limited. We investigated the cytokine response in skin and in serum in sepsis and its relation to multiorgan failure (MOF) and survival.', 'Cytokines were analysed in serum and in suction blister fluid of intact skin of 44 patients with severe sepsis and 15 healthy controls. Blister fluid and serum samples were collected within 48\xa0h of the first sepsis-induced organ failure. This is a substudy of a larger follow-up study on wound healing in sepsis.', 'Cytokine levels were higher in patients with sepsis vs. controls (interleukin [IL]-10, blisters: 65.9 vs. 4.3\xa0pg/ml, P\xa0<\xa00.001, serum: 25.7 vs. 4.5\xa0pg/ml, P\xa0=\xa00.004; IL-6, blisters: 41.9 vs. 0.03\xa0pg/ml, P\xa0<\xa00.001, serum: 45.5 vs. 2.1\xa0pg/ml, P\xa0<\xa00.001). Patients with MOF had higher levels of IL-10 (116.4 vs. 21.3\xa0pg/ml, P\xa0=\xa00.015), IL-4 (0.7 vs. 0.07\xa0pg/ml, P\xa0=\xa00.013) and basic fibroblast growth factor (bFGF) (25.9 vs. 9.5\xa0pg/ml, P\xa0=\xa00.027) in blister fluid than patients without MOF. In blister fluid, survivors had lower levels of IL-10 (43.3 vs. 181.9\xa0pg/ml, P\xa0=\xa00.024) and bFGF (15.8 vs. 31.9\xa0pg/ml, P\xa0=\xa00.006) than non-survivors. In serum, survivors had higher levels of vascular endothelial growth factor (VEGF) (152.2 vs. 14.7\xa0pg/ml, P\xa0=\xa00.012) and lower levels of IL-6 (38.5 vs. 91.1\xa0pg/ml, P\xa0=\xa00.011) than non-survivors. The blister fluid levels of bFGF, TNF and VEGF did not correlate with the serum levels.
[EX A]:
0