Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Ex Input:
Paragraph: Lawmakers are also expected to address abortion rights, private gun sales and environmental issues such as the rise in sea level. While the budget is the only thing the Legislature is constitutionally required to pass each year, there are already about 3,000 bills filed, including about 1,600 that seek to stuff local projects into the budget. Republican Gov. Ron DeSantis has declared 2020 “the year of the teacher.” He’s proposing a $91.4 billion budget that includes $600 million to raise the minimum salary for teachers to $47,500 a year. It also includes $1 million to help eradicate pythons in the Everglades and elsewhere — just one of the environmental initiates he wants the Legislature to approve. But the Legislature doesn’t have to follow the governor’s budget recommendations, and while House Speaker Jose Oliva has been diplomatic, he’s expressed some concern over the teacher pay proposal. “My initial thought is one of gratitude for those who came before us and saw it fit to bind us and all future legislatures to a balanced budget,” Oliva said when DeSantis announced the proposal. While several abortion bills have been filed on both sides of the debate, a bill requiring girls under 18 get their parents consent before having an abortion has a good chance of passing. Sen. Kelli Stargel is sponsoring the legislation and draws from her own experience as a pregnant teenager. “I thought for sure my mother would kill me when I told her that I was pregnant underage,” Stargel told her colleagues when presenting the bill. “She advised me to have an abortion. I chose not to have the abortion, but through that process, we are closer.” Florida already has a law that requires that a girl’s parents be notified if she gets an abortion, but it doesn’t require parents give their permission for the procedure. The parental consent bill would allow girls to ask a judge for a waiver if they are victims of abuse or incest. It’s one of several bills filed on both sides of the abortion issue, though most of the others are less likely to pass. There’s a House bill that would outlaw abortions if a doctor can detect a fetal heartbeat, but Senate President Bill Galvano said that would be tough to get through his chamber. Even more unlikely to pass is a bill to ask voters to change the constitution to require at least 50 percent of the House and Senate be comprised of women before lawmakers can vote on an abortion bill. Democratic Sen. Lauren Book said she sponsored the bill to serve as a talking point after the Alabama Senate sent a heartbeat bill to the governor with only two female senators voting on the legislation. “Having to watch two women, whose backs were certainly against the wall in a chamber like that, having to speak up for millions of women who had no voice and no representation in that chamber,” Book said. “I started drafting it after that.” Lawmakers will once again consider new gun laws two years after the Parkland high school shooting that left 17 dead. Galvano directed Infrastructure and Security Committee Chairman Sen. Tom Lee to come up with gun safety legislation after mass shootings across the country last year. Lee won’t go as far as Democratic proposals to ban assault rifles and large capacity magazines, but he said he’s considering changes to better document private gun sales. “It seems to me like the best thing we can do to enhance public safety is to take a look at the systems that we use or the requirements that we have in law for people to transfer or sell weapons between individuals,” Lee said. The environment will also be a top issue. Lawmakers are considering legislation that addresses the algae blooms that have plagued Florida in recent years. Republicans are also backing bills to create the Statewide Office of Resiliency and the Statewide Sea-Level Rise Task Force. The Department of Environmental Protection would be directed to take action based on the task force’s recommendations. Then there are hundreds of miscellaneous bills that won’t be among the most hotly debated, such as legislation that would ban “pet leasing,” which is essentially rent-to-own contracts some pet stores offer consumers. Then there’s Book’s bill to designate coconut patties as the official state candy. “This is very serious legislation,” Book said with a laugh. “I thought it would be fun and light, and people are very opinionated about it. Why not salt water taffy? Why not pink Starbursts? We feel strongly about Reese’s Peanut Butter Cups. And I’m like, ‘Guys, but this is created in Florida.’” Claim: From coconut patties to guns, lawmakers ready for session.

Ex Output:
The 60-day Florida legislative session that begins Tuesday will have lawmakers considering everything from coconut patties to a state budget expected to exceed $90 billion.


Ex Input:
Paragraph: Cancer patients increasingly are having their care guided by gene tumor boards, a new version of the hospital panels that traditionally decided whether surgery, radiation or chemotherapy would be best. These experts study the patient’s cancer genes and match treatments to mutations that seem to drive the disease. “We dissect the patient’s tumor with what I call the molecular microscope,” said Dr. Razelle Kurzrock, who started a board at the University of California, San Diego, where Cairnes is treated. It’s the kind of care many experts say we should aim for — precision medicine, the right drug for the right person at the right time, guided by genes. There are success stories, but also some failures and many questions: Will gene-guided care improve survival? Does it save money or cost more? What kind of gene testing is best, and who should get it? “I think every patient needs it,” especially if cancer is advanced, said Kurzrock, who consults for some gene-medicine companies. “Most people don’t agree with me — yet. In five years, it may be malpractice not to do genomics.” Few people get precision medicine today, said Dr. Eric Topol, head of the Scripps Translational Science Institute. “The only thing that’s gone mainstream are the words.” HOW IT WORKS NOW If you have a cancer that might be susceptible to a gene-targeting drug, you may be tested for mutations in that gene, such as HER2 for breast cancer. Some breast or prostate cancer patients also might get a multi-gene test to gauge how aggressive treatment should be. Then most patients get usual guideline-based treatments. If there’s no clear choice, or if the disease has spread or comes back, doctors may suggest tumor profiling — comprehensive tests to see what mutations dominate. That’s traditionally been done from a tissue sample, but newer tests that detect tumor DNA in blood — liquid biopsies — are making profiling more common. The tests cost about $6,000 and many insurers consider them experimental and won’t pay. Gene tumor boards analyze what the results suggest about treatment. They focus on oddball cases like a breast cancer mutation in a colon cancer patient, or cancers that have widely spread and are genetically complex. The only options may be experimental drugs or “off-label” treatments — medicines approved for different situations. But as tumor profiling grows, it’s revealing how genetically diverse many tumors are, and that oddball cases are not so rare, said Dr. John Marshall. He heads the virtual tumor board at Georgetown Lombardi Comprehensive Cancer Center that also serves cancer centers in Pennsylvania, North Carolina, Michigan and Tennessee. “There is a little bit of faith” that testing will show the right treatment, but it’s not a sure thing, said Dr. Lee Schwartzberg, who heads one participating center, the West Cancer Center in Memphis. Dr. Len Lichtenfeld, the American Cancer Society’s deputy chief medical officer, is optimistic yet wary. Drugs that target BRAF mutations work well for skin cancers called melanomas, but less well for lung or colon cancers. “Just because a mutation occurs it doesn’t mean that drug is going to work in that cancer,” he said. LUCKY CASES When it does, results can be dramatic. Cairnes’ cancer was between her stomach and esophagus, and had spread to her liver, lungs and lymph nodes. Tissue testing found 10 abnormal genes, but on the liquid biopsy only EGFR popped out as a good target. Two drugs aim at that gene but aren’t approved for her type of cancer. A tumor board advised trying both — Erbitux and Tarceva, the drug her husband also had taken. Within two weeks, she quit using pain medicines. After two months, her liver tumor had shrunk roughly by half. There are signs that cancer may remain, but it is under control. She feels well enough to travel and to take care of her granddaughter. “I’m very, very grateful to have a targeted therapy,” Cairnes said. “I cannot expect a better outcome than what we’re seeing right now,” said her doctor, Shumei Kato. WHAT STUDIES SHOW But is gene-guided treatment better than usual care? French doctors did the first big test, with disappointing results. About 200 patients with advanced cancer were given whatever their doctors thought best or off-label drugs based on tumor profiling. Survival was similar — about two months. Another French study, reported in June, was slightly more encouraging on survival but exposed another problem: No drugs exist for many gene flaws. Tests found treatable mutations in half of the 2,000 participants and only 143 got what a tumor board suggested. Some doctors worry that tumor boards’ recommending off-label treatments diverts patients from research that would benefit all cancer patients. For example, the American Society of Clinical Oncology’s TAPUR study tests off-label drugs and shares results with their makers and federal regulators. LETTING PATIENTS CHOOSE Ann Meffert, who lives on a dairy farm in Waunakee, Wisconsin, endured multiple standard treatments that didn’t defeat her bile duct cancer. “She was going to be referred to hospice; there was not much we could do,” said Dr. Nataliya Uboha, who took the case to a tumor board at the University of Wisconsin-Madison. The panel gave several options, including off-label treatment, and Meffert chose a study that matches patients to gene-targeting therapies and started on an experimental one last October. “Two weeks in, I started feeling better,” she said, and when she saw test results, “I couldn’t believe the difference.” Many lung spots disappeared and the liver tumor shrank 75 percent. She is not cured, though, and doctors are thinking about next steps. And that could involve a fresh look at her tumor genes. ___ Marilynn Marchione can be followed at @MMarchioneAP __ This Associated Press series was produced in partnership with the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. Claim: Ultra-personal therapy: Gene tumor boards guide cancer care.

Ex Output:
Doctors were just guessing a decade ago when they gave Alison Cairnes’ husband a new drug they hoped would shrink his lung tumors. Now she takes it, but the choice was no guesswork. Sophisticated gene tests suggested it would fight her gastric cancer, and they were right.


Ex Input:
Paragraph: The funding will help the clinics provide free or low-cost medical, dental and mental health care services to uninsured and underinsured Michigan residents, according to Blue Cross. The funding also pays for substance use disorder treatment. Grants of up to $25,000 each were awarded to 17 clinics. Another 30 clinics were awarded up to $15,000 each. Recipients expect to provide care to more than 60,000 people this year. More than 50,000 people received services through the program last year. Health care organizations offering primary care services also received more than $190,000 in matched funding through the program. Blue Cross has provided more than $15 million in grants since 2005 so safety net clinics can care for the uninsured and under-insured. Detroit-based Blue Cross Blue Shield of Michigan is a nonprofit mutual insurance company. Claim: Clinics awarded grants to help uninsured, underinsured.

Ex Output:

Nearly four dozen clinics will share $860,500 through Blue Cross Blue Shield of Michigan’s Strengthening the Safety Net program.