In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

[EX Q]: Paragraph: Mouse hepatitis virus, a coronavirus, was rescued from latently infected mouse neuroblastoma cells by polyethylene glyeol-induced fusion to permissive cells. The isolated viruses grew to equal or higher titers than parental JHM virus at 39" but were restricted in replication at 32" and hence were cold-sensitive mutants. Neither isolate synthesized RNA at the nonpermissive temperature (32"), and temperature shift experiments indicated that the restrictive cold-sensitive step in replication occurred during an early viral function. The isolates were unable to complement each other at 32". Although coinfection between each mutant and parental JHM virus often resulted in decreased yields of both infecting viruses, interference could not be convincingly demonstrated. Both mutants were more thermostable than parental JHM virus and could be distinguished from each other and from parental JHM virus by their thermal inactivation kinetics. The isolates were obtained from single cell clones and therefore presumed to be homogeneous; however, thermal inactivation of one (S-3JHM) indicated the possible existence of a second population. Subclones of virus prepared from each isolate were also found to be thermally stable and to retain the cold sensitive defect. No indication of a second ~pulation of S-3JHM virus was detected. 
 Title: Characterization of the Cold-Sensitive Murine Hepatitis Virus Mutants Rescued from Latently Infected Cells by Cell Fusion
[EX A]: True

[EX Q]: Paragraph: Antisense oligonucleotides and short interfering RNAs (siR-NAs) are nucleic acids-targeting reagents for gene expression modulation that are being developed as drugs for many applications. A number of useful synthetic nucleic acids analogues have been introduced recently to greatly improve their properties for use as therapeutics. However, their full effectiveness in cells and in vivo has often only been realized through development of suitable nonviral delivery systems. Among these, a range of natural and synthetic peptides have been found useful for enhancing cellular uptake and/or cell targeting of oligonucleotide analogues and siRNA. Such peptides are synthetically conjugated, used as noncovalent complexes, or used in combination with polymer, liposomal or exosome formulation techniques. This review begins by describing the modes of action of antisense reagents and siRNA and goes on to focus on recent advances in their peptide-mediated cell and in vivo delivery and how peptide use has influenced drug development. The review discusses the challenges associated with understanding the physiological and toxicological aspects of peptide-mediated delivery. Developments towards clinical use are also highlighted, with particular emphasis on peptide conjugates of oligonucleotide analogues used for treatment of neuromuscular diseases. 
 Title: Citation: Molecular Therapy-Nucleic Acids (2011) 1, e27; Molecular Therapy-Nucleic Acids (2012) 1, e27
[EX A]: True

[EX Q]: Paragraph: ThermoBioStar's and Biota's £u optical immunoassay (FLU OIA) is a rapid test designed to diagnose in£uenza A and B infection using a variety of specimen types. The assay uses highly sensitive thin-¢lm detection methods, coupled with speci¢c monoclonal antibodies to the nucleoprotein. The test is simple to perform, requires no instrumentation and is intended to provide a result within 15 min of test initiation in the`point-of-care' environment. In initial clinical studies, the assay was demonstrated to be equivalent to culture in identifying infected individuals. Subsequent independent studies using a variety of sample types have demonstrated sensitivity ranging from 48 to 100% and speci¢cities ranging from 93 to 97%. In addition to detecting human strains, this assay has been demonstrated to be capable of detecting a variety of avian and non-human mammalian in£uenza viruses. The FLU OIA test has been used in large-scale surveillance schemes intended to provide rapid epidemiological data during normal in£uenza seasons and has demonstrated the potential for ful¢lling a similar role for multispecies surveillance in, for example, conditions that o¡er challenges for conventional virus isolation methods. Conceivably, such use should facilitate the timely recognition of in£uenza outbreaks and prioritization of positive specimens for more conventional, laboratory characterization, leading to improved interpandemic surveillance and rapid reaction in the face of the next pandemic. 
 Title: A¯u optical immunoassay (ThermoBioStar's FLU OIA): a diagnostic tool for improved in¯uenza management
[EX A]:
False