Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
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Question: Context: The film opens with Soichi Negishi (Kenichi Matsuama) walking along side his mother to a small country train station. Negishi hopes to move to Japan, and realize his musical dreams, as a pop singer. As he rides away in the train, he sees his younger brother wave to him from a field.Now we are taken to a dark alleyway, where many alternative Japanese youths are entering a club called "Hell's Gate." Inside we see a death metal band(in rather flamboyant attire, and black and white make-up) preforming for a large crowd. This band, is Detroit Metal City. The singer, is then revealed to be Negashi, and why crowd surfing he narrates of his dislike of what he has become.The opening credits roll.We now see Negashi removing his makeup with a rag, and talking a fellow band mate, which is his lazy, bloomer obsessed drummer Terumichi Nishida . He begs Nishida to return a video-game he had let him borrow, out of fear of him losing it. Now the band's bassist Masayuki Wada speaks to Negashi about how well he believed the show had done.The dressing room door bursts open, and with a wild laugh the President Of Death Records(who also seems to be the band's manager) enters, and tosses a cigarette into a ash tray that Wada held, but it simply bounced out and went out of frame. She told them of how well they did, but in remorse Negashi played for her a tape of the pop music he wishes to make. Displeased, she kicked him.Now with a swollen mouth, Negashi leaves the dressing room in his normal attire, and pushes his way through the crowd of oblivious screaming fans, hoping to get a look at the band. He is hit, and begins to bleed from the nose. As he made his way up the stairs, he heard the fans talk of rumors they had heard about the lead singer Krauser, such as his ability to rape many women.Negashi is now on the street, and he is playing his pop music on an acoustic guitar, with people only stoping to glance at him, and then walk away. He stops playing and hears some pop music being played around the corner. As he goes to investigate he sees that the lead singer of the band was an old college friend, and then that a woman standing near him was his college crush Yuri Aikawa.He reflects on the old days, of them all sitting around playing music together, and of his quote "No music, No dream."He is soon at a record store, looking at the latest fashionable cd covers, when he sees Aikawa, and they began to chat, and make plans to meet later at a cafe. Then a blast of near-by music startles him, and he walks to the next isle to investigate. Several DMC fans had gathered to celebrate the release of a new single with head-banging, and loud music. Negashi dislikes the album cover, and complains about a quote that was in his name, that he never said. Aikawa then tells him of her distaste for metal, and how unfashionable she finds Detroit Metal City.Negashi is now in full attire with his band, doing an interview about the new single. His mind is off daydreaming about Aikawa when he realizes it is time for their date and he runs out of the interview to meet her. Negashi is now constantly going back and forth between the date, and the interview, each time forgetting to remove more and more of his DMC attire. With a feeling that negashi was going into the near-by club, she enters in hopes of finding him, but meets Krauser crowd surfing. Negashi in fear, tries to get the crowd to move him away from her, but the get him closer and closer, until he felt his wig began to slip off. The only thing he could do to cover himself, was to lift up her dress, showing her underwear. She calls him a pig, and walks out.Now Negashi is outside of a cafe, and is banging on the wall in 
 Question: Who is he in stage costume?

Answer: krauser


Question: Context: The mechanism of action, pharmacokinetics, and use of flumazenil in benzodiazepine overdose, as well as in the management of other disease states, are reviewed. Flumazenil interacts at the central benzodiazepine receptor to antagonize or reverse the behavioral, neurologic, and electrophysiologic effects of benzodiazepine agonists and inverse agonists. Flumazenil has been studied for a variety of indications, including as an antidote to benzodiazepine overdose and for awakening of comatose patients, reversal of sedation after surgery and in critically ill patients, and management of hepatic encephalopathy. It improves the level of consciousness in patients with benzodiazepine overdose; however, resedation may occur within one to two hours after administration, so repeated doses or a continuous infusion may be required to maintain therapeutic efficacy. It appears to be effective in reversing sedation induced by midazolam or diazepam, and case reports suggest that it is useful in awakening comatose patients, although its clinical utility is questionable. Flumazenil has proved useful in reversing conscious sedation in critically ill patients, although response may be dose dependent. Animal models indicate that flumazenil is of some benefit in hepatic encephalopathy, but until well-designed clinical trials are conducted, hepatic encephalopathy must be considered an investigational indication for flumazenil. Adverse reactions include CNS manifestations, resedation, cardiovascular effects, seizures, and alterations in intracranial pressure and cerebral perfusion pressure. Hepatic dysfunction results in a substantial change in the pharmacokinetic profile of flumazenil; therefore, dosage adjustment may be necessary in patients with hepatic dysfunction or in those receiving medications that alter flumazenil metabolism. Flumazenil has been shown to reverse sedation caused by intoxication with benzodiazepines alone or benzodiazepines in combination with other agents, but it should not be used when cyclic antidepressant intoxication is suspected. It may be beneficial after surgery when benzodiazepines have been used as part of anesthesia and after a diagnostic or surgical procedure when assessment of CNS function is necessary. 
 Question: Which drug should be used as an antidote in benzodiazepine overdose?

Answer: flumazenil


Question: Context: In the last few years, several tyrosine kinase inhibitors (TKIs) have been synthesized and become available for preclinical studies and clinical trials. This article summarizes recent achievements in the mechanism of action, pharmacological properties, and clinical activity and toxicity, as well as the emerging role of TKIs in lymphoid malignancies, allergic diseases, and autoimmune disorders. A literature review was conducted of the MEDLINE database PubMed for articles in English. Publications from 2000 through January 2012 were scrutinized. The search terms used were Bruton's tyrosine kinase (Btk) inhibitors, PCI-32765, GDC-0834, LFM-A13, AVL-101, AVL-292, spleen tyrosine kinase (Syk) inhibitors, R343, R406, R112, R788, fostamatinib, BAY-61-3606, C-61, piceatannol, Lyn, imatinib, nilotinib, bafetinib, dasatinib, GDC-0834, PP2, SU6656 in conjunction with lymphoid malignancy, NHL, CLL, autoimmune disease, allergic disease, asthma, and rheumatoid arthritis. Conference proceedings from the previous 5 years of the American Society of Hematology, European Hematology Association, American Society of Clinical Oncology, and ACR/ARHP Annual Scientific Meetings were searched manually. Additional relevant publications were obtained by reviewing the references from the chosen articles. The use of TKIs, especially inhibitors of Btk, Syk, and Lyn, is a promising new strategy for targeted treatment of B-cell lymphoid malignancies, autoimmune disorders and allergic diseases. However, definitive data from ongoing and future clinical trials will aid in better defining the status of TKIs in the treatment of these disorders. 
 Question: Which enzyme is inhibited by a drug fostamatinib?

Answer:
spleen tyrosine kinase