instruction:
In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
question:
 Using the specific pharmacological inhibitors of PI 3 - kinase , Wortmannin and LY294002 , we demonstrate that PI 3 - kinase activity is vital for BCR - induced NF - kappaB DNA - binding activity .
answer:
NF - kappaB


question:
 However , it remains unclear whether GATA - 3 plays a role in the effector phase of allergic airway inflammation and whether antagonizing the expression and / or function of GATA - 3 can be used for the therapy of allergic airway inflammation and hyperresponsiveness .
answer:
GATA - 3


question:
 The role of transcription factor activation in other models of pancreatitis has not been established .
answer:

transcription factor