You are given two sentences. You have to find if there is entailment or agreement of the Hypothesis by the Premise. From the given pair of sentences, you should identify if there is enough information in the Premise to support the claim made in the Hypothesis. The Premise may not exactly be the same as Hypothesis. Your task is to return 'entails' if the premise supports hypothesis else return 'neutral'.

Q: Premise: The cave populations have retained the capacity to produce fertile offspring with surface fish and are considered to be the same species (Avise and Selander, 1972). 
 Hypothesis: If two populations do not mate and produce fertile offspring, separate species result.

A: neutral
****
Q: Premise: In general there are four major classes of compounds that comprise most biological materials. 
 Hypothesis: There are four classes of biochemical compounds.

A: entails
****
Q: Premise: Cigarette smoke contains more than 4,000 different chemicals, many of which are proven carcinogens, while hundreds of others increase the cancer causing power of carcinogens. 
 Hypothesis: Cigarettes are a major source of carcinogens, a kind of chemical substances linked with cancer.

A:
entails
****