TASK DEFINITION: In medical studies, the efficacy of medical treatments (called interventions) is evaluated within a group of study participants. You will be given a sentence of a study report in which your task is to list the phrases that describe the intervention(s) of the study. You should list the phrase in the same order that they appear in the text, separated by commas. If no information about the interventions is mentioned, just answer with "not found". Interventions are: a specific drug, surgery, talking therapy, a lifestyle modification, control or placebo treatment. Do not include details, dosages, frequency and duration, intervention mentions that are not in an informative span of text.
PROBLEM: CALGB 8642 randomizes previously untreated metastatic breast cancer patients either to one of several Phase II agents given for up to four cycles and then followed by standard cyclophosphamide-doxorubicin-5-fluorouracil , or to immediate treatment with standard cyclophosphamide-doxorubicin-5-fluorouracil .

SOLUTION: cyclophosphamide-doxorubicin-5-fluorouracil

PROBLEM: Risk factors retained in the model included poor performance status , absolute neutrophil count < or =2.0 x 10 ( 9 ) cells/L in the previous cycle , the first cycle of chemotherapy , DOX versus PLD and advanced age .

SOLUTION: not found

PROBLEM: Patients did not practise the exhalation manoeuvre prior to testing .

SOLUTION:
not found