In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Ex Input:
Question: Reactions in which there are no intermediates are described as: 
 Options:  <1> Concerted. <2> Polar <3> Radicals <4> Homolitic <5> Heterolithic

Ex Output:
1


Ex Input:
Question: With regard to pyrogens and biotechnological medicines, it is possible to say: 
 Options:  <1> They have no tendency to aggregate or form large units with high molecular weight. <2> Ion exchange chromatography procedures (using their positive charge) can reduce endotoxin levels. <3> Ion exchange chromatography procedures (using their negative charge) can reduce endotoxin levels. <4> Ion exchange chromatography procedures (regardless of their charge) can reduce endotoxin levels. <5> They are unstable under standard autoclaving conditions.

Ex Output:
3


Ex Input:
Question: The three human chromosomes estimated to contain fewer genes are: 
 Options:  <1> 21, 22 and Y. <2> 18, 22 and Y. <3> 18, 21 and Y. <4> 13, 21 and Y. <5> 13, 22 and Y.

Ex Output:

3