Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Ex Input:
In melanoma, transition to the vertical growth phase is the critical step in conversion to a deadly malignant disease. Here, we offer the first evidence that an antioxidant enzyme has a key role in this transition. We found that the antioxidant enzyme peroxiredoxin-2 (Prx2) inversely correlated with the metastatic capacity of human melanoma cells. Silencing Prx2 expression stimulated proliferation and migration, whereas ectopic expression of Prx2 produced the opposite effect. Mechanistic investigations indicated that Prx2 negatively regulated Src/ERK activation status, which in turn fortified adherens junctions function by increasing E-cadherin expression and phospho-Y654-dependent retention of -catenin in the plasma membrane. In murine melanoma cells, Prx2 silencing enhanced lung metastasis in vivo. Interestingly, the natural compound gliotoxin, which is known to exert a Prx-like activity, inhibited proliferation and migration as well as lung metastasis of Prx2-deficient melanoma cells. Overall, our findings reveal that Prx2 is a key regulator of invasion and metastasis in melanoma, and also suggest a pharmacologic strategy to effectively decrease deadly malignant forms of this disease.

Ex Output:
What type of enzyme is peroxiredoxin 2 (PRDX2)?


Ex Input:
Anna Foster (Mandy Moore) is the daughter of the President of the United States, James (Mark Harmon) and First Lady Michelle Foster (Caroline Goodall).When a hassle of Secret Service agents ruins a first date, Anna demands some freedom. Her dad agrees to send only two agents with Anna and Gabrielle La Clare (Beatrice Rosen) to a concert when Anna goes to Prague with her parents. A sexy new look for Anna causes her father to renege. When Anna discovers the concert is filled with agents and that her father has broken his promise, Gabrielle helps Anna elude her protectors. Outside the concert, Anna meets Ben Calder (Matthew Goode), and asks him to drive her to escape the agents. Anna goes to a bar with Ben and proceeds to get drunk. Unbeknownst to Anna, Ben is with the Secret Service, and tells agents Alan Weiss (Jeremy Piven) and Cynthia Morales (Annabella Sciorra) where Anna is. The President orders the three agents to have Ben guard Anna without telling her who he really is, to give her an illusion of freedom with a guarantee of safety. Believing herself free of her guards for the first time in years, Anna jumps into the Vltava River naked, mistaking it for the Danube, and Ben has to fish her out (he stays clothed). Weiss and Morales buy the camera from someone taking pictures of the skinny-dipping Anna. Anna and Ben climb a rooftop to watch an opera being shown in a plaza, where Anna eventually falls asleep with Ben guarding her, and Weiss and Morales watching from another roof.The next morning, Anna calls her parents to avoid getting into further trouble with them. Knowing she is safe, her father is initially indulgent, and Anna is about to return, but his tone changes when he is shown the photos of her nude in the river. The First Lady, however, asks, "What happened to 'let freedom ring?'" (That had been his earlier line when he had decided to let her stay out with Ben.) Anna is outraged at both her dad's sudden imperious tone and finding out that he traced her call. She decides to meet Gabrielle at the Love Parade in Berlin and return to her parents right before the plane trip home. Ben goes with her on the train, where they meet Scotty McGruff (Martin Hancock), a flighty romantic obsessed with Six Million Dollar Man stickers and the interconnectivity of the world, he gives them a stack of stickers and tells them to stick them up in random places, then one day when they are unhappy, they will see one and it will make them smile. Through him, the two learn that they have boarded a Venice-bound train. When they arrive in Venice, Ben calls the other agents to tell them where they are but has to leave the phone dangling when he realizes he can no longer see Anna. He finds her and McGruff getting new clothes, and the three explore Venice - until McGruff steals their wallets. Ben is about to tell the cafe they cannot pay when Anna is recognized and races off to avoid being identified as the First Daughter. Ben follows, and they tell a story of marrying, against the wishes of Anna's parents, to get a gondola ride from a kind-hearted gondolier, Eugenio (Joseph Long). Ben kisses Anna during the ride to hide her from the cafe staff's sight. Since they have no place to stay, Eugenio invites them to his and his mother Maria's (Miriam Margolyes) house. That night, thinking the kiss meant that Ben cares for her, Anna offers herself to him. To dissuade her, Ben is disingenuous and harsh. Anna finally gets in the bed alone, while Ben lies on the floor.The next day, Eugenio drives them to the Austrian border, as Weiss and Morales show up at Maria's looking for the gondolier with whom Anna and Ben were last seen. Maria tells them that Anna and Ben are married, which is reported to Anna's parents. Upset that Ben rejected her, Anna gets a ride on a truck, leaving Ben to

Ex Output:
What is Anna's dad occupation?


Ex Input:
Salif Diallo (born 9 May 1957) is a Burkinabe politician who has been President of the National Assembly of Burkina Faso since 2015.

Ex Output:

What country did Salif Diallo come from?