In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

[Q]: Paragraph: h i g h l i g h t s • We obtained a spatial epidemic model with logistic growth. • Using multiple-scale analysis, we present amplitude equations. • There are different types of stationary patterns. • Reaction diffusion epidemic systems have rich dynamics. Mathematical models are very useful in analyzing the spread and control of infectious diseases which can be used to predict the developing tendency of the infectious disease, determine the key factors and to seek the optimum strategies of disease control. As a result, we investigated the pattern dynamics of a spatial epidemic model with logistic growth. By using amplitude equation, we found that there were different types of stationary patterns including spotted, mixed, and stripe patterns, which mean that spatial motion of individuals can form high density of diseases. The obtained results can be extended in other related fields, such as vegetation patterns in ecosystems. 
 Title: Physica A Dynamics of an epidemic model with spatial diffusion
[A]: True


[Q]: Paragraph: Uropathogenic E. coli (UPEC), which cause urinary tract infections (UTI), utilize type 1 pili, a chaperone usher pathway (CUP) pilus, to cause UTI and colonize the gut. The pilus rod, comprised of repeating FimA subunits, provides a structural scaffold for displaying the tip adhesin, FimH. We solved the 4.2 Å resolution structure of the type 1 pilus rod using cryo-electron microscopy. Residues forming the interactive surfaces that determine the mechanical properties of the rod were maintained by selection based on a global alignment of fimA sequences. We identified mutations that did not alter pilus production in vitro but reduced the force required to unwind the rod. UPEC expressing these mutant pili were significantly attenuated in bladder infection and intestinal colonization in mice. This study elucidates an unappreciated functional role for the molecular spring-like property of type 1 pilus rods in host-pathogen interactions and carries important implications for other pilus-mediated diseases. 
 Title: Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions
[A]: False


[Q]: Paragraph: Coronaviral infection is associated with up to 5% of respiratory tract diseases. The 3C-like protease (3CL pro ) of coronaviruses is required for proteolytic processing of polyproteins and viral replication, and is a promising target for the development of drugs against coronaviral infection. We designed and synthesized four nitrile-based peptidomimetic inhibitors with different N-terminal protective groups and different peptide length, and examined their inhibitory effect on the in-vitro enzymatic activity of 3CL pro of severe-acute-respiratory-syndrome-coronavirus. The IC 50 values of the inhibitors were in the range of 4.6e49 mM, demonstrating that the nitrile warhead can effectively inactivate the 3CL pro autocleavage process. The best inhibitor, Cbz-AVLQ-CN with an N-terminal carbobenzyloxy group, was w10x more potent than the other inhibitors tested. Crystal structures of the enzymeeinhibitor complexes showed that the nitrile warhead inhibits 3CL pro by forming a covalent bond with the catalytic Cys145 residue, while the AVLQ peptide forms a number of favourable interactions with the S1eS4 substratebinding pockets. We have further showed that the peptidomimetic inhibitor, Cbz-AVLQ-CN, has broadspectrum inhibition against 3CL pro from human coronavirus strains 229E, NL63, OC43, HKU1, and infectious bronchitis virus, with IC 50 values ranging from 1.3 to 3.7 mM, but no detectable inhibition against caspase-3. In summary, we have shown that the nitrile-based peptidomimetic inhibitors are effective against 3CL pro , and they inhibit 3CL pro from a broad range of coronaviruses. Our results provide further insights into the future design of drugs that could serve as a first line defence against coronaviral infection. 
 Title: Design, synthesis and crystallographic analysis of nitrile-based broad-spectrum peptidomimetic inhibitors for coronavirus 3C-like proteases
[A]:
True