Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does the ets-domain transcription factor Spdef promote maturation of goblet and paneth cells in the intestinal epithelium?
Answer: Spdef acts downstream of Math1 to promote terminal differentiation of a secretory progenitor pool into Paneth and goblet cells.
yes

Question: Does identification of structural alert for liver and kidney toxicity using repeated dose toxicity data?
Answer: It was not possible to assign an unambiguous mode of action for all the SAs, but a mechanistic explanation is provided for some of them. Such achievements may help in the early identification of liver and renal toxicity of substances.
yes

Question: Does l-Tryptophan influence acute ventilatory response at moderate altitude?
Answer: L-tryptophan does not impair ventilatory adaptation to mild hypoxia at moderate altitude.

no