In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

Q:  We have also detected a DNA - protein interaction that may be involved in the cell - type specificity of immunoglobulin expression , and we have determined that a sequence upstream of the octamer participates in an interaction with a nuclear protein ( s ) .

A: nuclear protein
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Q:  This signaling pathway may be crucial for the control of B - cell differentiation and antibody response and has implications for the regulation of other POZ / zinc finger transcription factors in other tissues .

A: transcription factors
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Q:  Although the inhibitors prevented both pervanadate - induced phosphorylation of I kappa B - alpha on Tyr42 and NF - kappa B activation , we observed that , in p56 ( lck ) - deficient Jurkat mutants , NF - kappa B could still associate with I kappa B - alpha despite phosphorylation on Tyr42 .

A:
I kappa B
****