TASK DEFINITION: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
PROBLEM: Question: ADH increases the osmolality of the renal interstitial medium because it increases: 
 Options:  <1> The permeability to urea in the collector tube. <2> The water permeability of the ascending loop of Henle. <3> The flow in the straight vessels. <4> The reabsorption of NaCl in the collecting tubule. <5> The renal excretion of water.

SOLUTION: 1

PROBLEM: Question: It has been proved that the dissolution speed of the solvate that is formed when the griseofulvin and the chloroform are associated, is: 
 Options:  <1> Less than the unsolvated form of the drug. <2> Limiting step of the disintegration of the tablets in which the drug is formulated. <3> Greater than the unsolvated form of the drug. <4> Limiting factor of the distribution of the drug to the aqueous sectors of the organism. <5> Same as the unsolvated form of the drug.

SOLUTION: 3

PROBLEM: Question: When carrying out the validation of an analytical method it is necessary to take into account the following basic aspects: 
 Options:  <1> Validate the analytical process as a whole, the range of concentrations in which it is applied, as well as the method in a single matrix to ensure selectivity. <2> Validate the previous stages of treatment of the sample, the range of concentrations in which it is applied and the method in a single matrix to ensure the selectivity. <3> Validate the final measurement method, validate the range of low concentrations (traces) in which it is applied and the method in a single matrix to ensure sensitivity. <4> All that is required is to validate the instrumentation by means of suitable calibrations. <5> Validate the analytical process as a whole, the concentration interval in which it is applied and the method in each of the matrices to which it will be applied.

SOLUTION:
5