Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Input: Consider Input: Context: Our previous work has shown that gene knockout of the sodium-glucose cotransporter SGLT2 modestly lowered blood glucose in streptozotocin-diabetic mice (BG; from 470 to 300 mg/dl) and prevented glomerular hyperfiltration but did not attenuate albuminuria or renal growth and inflammation. Here we determined effects of the SGLT2 inhibitor empagliflozin (300 mg/kg of diet for 15 wk; corresponding to 60-80 mgkg(-1)day(-1)) in type 1 diabetic Akita mice that, opposite to streptozotocin-diabetes, upregulate renal SGLT2 expression. Akita diabetes, empagliflozin, and Akita + empagliflozin similarly increased renal membrane SGLT2 expression (by 38-56%) and reduced the expression of SGLT1 (by 33-37%) vs. vehicle-treated wild-type controls (WT). The diabetes-induced changes in SGLT2/SGLT1 protein expression are expected to enhance the BG-lowering potential of SGLT2 inhibition, and empagliflozin strongly lowered BG in Akita (means of 187-237 vs. 517-535 mg/dl in vehicle group; 100-140 mg/dl in WT). Empagliflozin modestly reduced GFR in WT (250 vs. 306 l/min) and completely prevented the diabetes-induced increase in glomerular filtration rate (GFR) (255 vs. 397 l/min). Empagliflozin attenuated increases in kidney weight and urinary albumin/creatinine ratio in Akita in proportion to hyperglycemia. Empagliflozin did not increase urinary glucose/creatinine ratios in Akita, indicating the reduction in filtered glucose balanced the inhibition of glucose reabsorption. Empagliflozin attenuated/prevented the increase in systolic blood pressure, glomerular size, and molecular markers of kidney growth, inflammation, and gluconeogenesis in Akita. We propose that SGLT2 inhibition can lower GFR independent of reducing BG (consistent with the tubular hypothesis of diabetic glomerular hyperfiltration), while attenuation of albuminuria, kidney growth, and inflammation in the early diabetic kidney may mostly be secondary to lower BG. 
 Question: Which protein does empagliflozin inhibit?

Output: sglt2


Input: Consider Input: Context: The story is not linked to the first part of the series. Instead, it focuses on a fictional explanation for the Ryanggang explosion in 2004, in which an unexplained mushroom cloud occurred in North Korea. After reconnaissance satellites detect a large, three-stage Topol intercontinental ballistic missile carrying a nuclear weapon in North Korea, which can strike anywhere in the continental United States, a fictional United States President Adair T. Manning (Peter Coyote) orders a team of U.S. Navy SEALs to destroy the missile and the launch site. The team is led by Lieutenant Robert James (Nicholas Gonzalez). The Pentagon aborts the mission after it receives new information, but by the time the abort order is sent, two SEALs have already parachuted into North Korean territory. James stops the third SEAL from deploying, accidentally knocking the man's helmet against the status indicator mounted near the door. The lieutenant steps onto the makeshift ramp to peer outside, returning to the doorway to inform the rest of men of the abort. The high-speed winds from outside rip the indicator loose and send it flying into the lieutenant's face. Stumbling backwards, James loses his balance and is sucked out of the plane. Callaghan disobeys orders to stand fast, strikes his commanding officer, and follows the first three, taking a radio with him. When North Korean forces led by Commander Hwang (Joseph Steven Yang) find the SEALs, two of the Navy SEALs are killed in a gun battle, and James and Callaghan are captured and tortured by Hwang and his men. After South Korean special forces rescue James and Callaghan, President Manning and the South Korean government send the SEALs and South Korean special forces to destroy the missile site. But after losing radio contact with the SEALs, the President and his top advisers believe that they have been captured again. Under pressure from his military advisor, General Norman Vance (Bruce McGill), the President decides to send B-2 stealth bombers to destroy the site, which would start a full-scale war against North Korea. The SEALs and the South Korean special forces are almost recaptured by Hwang, but he is shot by a defecting officer. James and the South Koreans destroy the missile silo with a bomb before the bombers reach the missile site, which averts the bombing and prevents a full-scale war. A tribunal convicts Callaghan of striking an officer (1 year) and disobeying an officer (10 years). Due to the "black op" nature of the mission, the transcript of the hearing is deemed classified and the charges are expunged from his record, leaving him free to return to his family. Meanwhile, James meets the president in a classified meeting, bringing his mentor Master Chief Scott Boytano (Keith David) as witness to James' receiving of an award. The film closes with Boytano telling James he wasn't red flagged because Boytano had never seen anyone who desired so badly as James did to be a SEAL. During the credits there is a news report on the Ryanggang explosion. 
 Question: Who destroys the missile silo?

Output: james and the south koreans


Input: Consider Input: Context: Mary McConneloug (born June 24, 1971 in San Francisco, California) is a female racing cyclist from the United States, specializing in competitive mountain biking. 
 Question: What gender is Mary McConneloug?


Output: female