Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Input: Consider Input: Context: Autosomal-recessive hereditary spastic paraplegias (AR-HSP) consist of a genetically diverse group of neurodegenerative diseases characterised by pyramidal tracts dysfunction. The causative genes for many types of AR-HSP remain elusive. We tried to identify the gene mutation for AR-HSP with cerebellar ataxia and neuropathy. This study included two patients in a Japanese family with their parents who are first cousins. Neurological examination and gene analysis were conducted in the two patients and two normal family members. We undertook genome-wide linkage analysis employing single nucleotide polymorphism arrays using the two patients' DNAs and exome sequencing using one patient's sample. We detected a homozygous missense mutation (c.4189T>G, p.F1397V) in the lysosomal trafficking regulator (LYST) gene, which is described as the causative gene for Chediak-Higashi syndrome (CHS). CHS is a rare autosomal-recessive syndrome characterised by hypopigmentation, severe immune deficiency, a bleeding tendency and progressive neurological dysfunction. This mutation was co-segregated with the disease in the family and was located at well-conserved amino acid. This LYST mutation was not found in 200 Japanese control DNAs. Microscopic observation of peripheral blood in the two patients disclosed large peroxidase-positive granules in both patients' granulocytes, although they had no symptoms of immune deficiency or bleeding tendency. We diagnosed these patients as having adult CHS presenting spastic paraplegia with cerebellar ataxia and neuropathy. The clinical spectrum of CHS is broader than previously recognised. Adult CHS must be considered in the differential diagnosis of AR-HSP. 
 Question: Which mutated gene causes the ChediakHigashi Syndrome?

Output: lysosomal trafficking regulator gene


Input: Consider Input: Context: New Orleans narcotics detective Anthony Stowe (Jean-Claude Van Damme) is a heroin addict who is teetering on the edge of oblivion, and he couldn't care less.At the moment, Stowe is trying to bring down his former partner Gabriel Callahan (Stephen Rea), who has become a drug kingpin. Callahan is trying to, and slowly succeeding at, taking over the New Orleans underworld.Stowe botches a sting operation against Callahan, resulting in the death of fellow cop Maria Ronson (Rachel Grant), whose fiancee, fellow cop Van Huffel (Adam Leese), is furious at Stowe. Chief Mac Baylor (Gary Beadle) has a very blunt chat with Stowe about it. Stowe is approached by fellow cop Walter Curry (Trevor Cooper) to help his nephew beat a drug-dealing charge. Stowe instead turns him over to Baylor, who fires him. After barricading himself in the station bathroom, Walter confronts an unrepentant Stowe and condemns him for betraying his fellow officers.Later, Van Huffel berates Stowe for getting Maria killed. Stowe responds by attacking Van Huffel in front of several officers. Later, Stowe meets with his estranged wife Valerie (Selina Giles), who tells him that she's pregnant, but that he's not the father. Valerie, whose marriage with Stowe is on the rocks, has been seeing a man named Mark Rossini (Mark Dymond), the gym teacher at the school she is principle of. But he may not be the father either. Stowe brashly accuses Valerie of being impregnated by Callahan, and Valerie tells him she never wants to see him again.The only thing keeping Stowe from total collapse is his dogged pursuit of Callahan. But he drunkenly stumbles into an ambush masterminded by Callahan, and is shot in the head by Callahan's right-hand man Jimmy (Stephen Lord).Stowe undergoes emergency surgery, and ends up in a coma. Months later, he recovers to the point that he opens his eyes, and is transported to his and Valerie's house to recover properly.Seven months after getting shot, Stowe has recovered a lot, although he must learn to walk and speak again. He manages to survive an attempt on his life, by someone who appears to be a cop. He's recovered enough to try to get his job back, but that's the one thing that Chief Baylor doesn't want to give him. The coma has led to his decision to become a better man, and to right some wrongs. He reconciles with his wife, although awkwardly, and gives Walter a check for $40,000, part of his insurance money that compensated his time in a coma. Finally, he visits the grave of fellow police officer Serge (William Ash), who once saved Stowe's life but has been killed by an unknown attacker following another failed sting operation.Valerie packs up to move out of the house so she can live with Mark, but after realizing the change that Stowe has undergone, she later decides to leave Mark and come back home. Stowe is convinced by his friend Chad Mansen (Wes Robinson) not to let his wife go, and Stowe goes after her. They miss each other by a few minutes.Just after Valerie returns and meets Chad, some of Callahan's men show up. Jimmy kills Chad, and kidnaps Valerie. Stowe returns to the house, and finds Chad's body, along with Jimmy waiting for him.Van Damme promoting the film in 2007Jimmy takes Stowe to a warehouse where Callahan is waiting. Along the way, Stowe manages to overpower Jimmy and take his gun, but he finds that the odds against him are impossible- and Callahan has Valerie hostage. Van Huffel is revealed to be Callahan's mole on the police force, and the sting operation at the beginning of the film was a set-up. Walter suddenly arrives and saves Stowe. Together they kill all of Callahan's men, including Jimmy and Van Huffel, as Callahan tries to escape with Valerie to his helicopter. Just as Callahan is about to reach it, Stowe appears.In the European DVD ending, each fire a shot that kills the other. Valerie cries out 
 Question: Who does Valerie want to live with when she leaves the house?

Output: mark


Input: Consider Input: Context: In the Atlantic, the West India Company concentrated on wresting from Portugal its grip on the sugar and slave trade, and on opportunistic attacks on the Spanish treasure fleets on their homeward bound voyage. Bahia on the north east coast of Brazil was captured in 1624 but only held for a year before it was recaptured by a joint Spanish-Portuguese expedition. In 1628, Piet Heyn captured the entire Spanish treasure fleet, and made off with a vast fortune in precious metals and goods that enabled the Company two years later to pay its shareholders a cash dividend of 70%, though the Company was to have relatively few other successes against the Spanish. In 1630, the Dutch occupied the Portuguese sugar-settlement of Pernambuco and over the next few years pushed inland, annexing the sugar plantations that surrounded it. In order to supply the plantations with the manpower they required, a successful expedition was launched in 1637 from Brazil to capture the Portuguese slaving post of Elmina, and in 1641 successfully captured the Portuguese settlements in Angola. In 1642, the Dutch captured the Portuguese possession of Axim in Africa. By 1650, the West India Company was firmly in control of both the sugar and slave trades, and had occupied the Caribbean islands of Sint Maarten, Curacao, Aruba and Bonaire in order to guarantee access to the islands' salt-pans. 
 Question: What did Piet Heyn get?


Output: vast fortune in precious metals