In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Input: Consider Input: Question: Ultraviolet radiation changes the structure of DNA by: 
 Options:  <1> Rupture of phosphodiester bonds. <2> Deamination of nitrogenous bases. <3> Depurinization <4> Formation of cyclobutyl rings of pyrimidines. <5> Hydroxylation of nitrogenous bases.

Output: 4


Input: Consider Input: Question: Which of the nucleophiles listed below has a greater reactivity to the bimolecular nucleophilic substitution reaction? 
 Options:  <1> Hydroxide. <2> I last. <3> Ammonia. <4> Water. <5> Acetic acid.

Output: 2


Input: Consider Input: Question: A promoter place in the DNA: 
 Options:  <1> Transcribe the repressor. <2> Start the transcription. <3> It encodes the RNA polymerase. <4> Regulate the termination. <5> Translate specific proteins.


Output: 2