Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: The potential for progressive brain injury and subsequent disability related to intraventricular IL-2 therapy is discussed.

Output: adverse drug event


Input: Consider Input: Hepatotoxicity induced by cyproterone acetate: a report of three cases.

Output: adverse drug event


Input: Consider Input: Acute cervico-facial oedema and loss of consciousness following ingestion of barracuda fish.


Output: non-adverse drug event