Given a text passage, come up with an appropriate title for it. The title should accurately represent what the main focus of the passage is. The title of a passage may be present in the first few sentences of the passage and/or be referred to multiple times in the passage. The title should be 1-5 words long.

[Q]: The Teenage Mutant Ninja Turtles ( often shortened to TMNT or Ninja Turtles ) are four fictional teenaged anthropomorphic turtles named after Italian artists of the Renaissance . They were trained by their anthropomorphic rat sensei in the art of ninjutsu . From their home in the sewers of New York City , they battle petty criminals , evil overlords , mutated creatures , and alien invaders while attempting to remain hidden from society . They were created by Kevin Eastman and Peter Laird .
[A]: Teenage Mutant Ninja Turtles


[Q]: Leeds is located 190 miles ( 310 km ) north - northwest of London , on the valley of the River Aire in the eastern foothills of the Pennines . The city centre lies in a narrow section of the Aire Valley at about 206 feet ( 63 m ) above sea level ; while the district ranges from 1,115 feet ( 340 m ) in the far west on the slopes of Ilkley Moor to about 33 feet ( 10 m ) where the rivers Aire and Wharfe cross the eastern boundary . The centre of Leeds is part of a continuously built - up area extending to Pudsey , Bramley , Horsforth , Alwoodley , Seacroft , Middleton and Morley .
[A]: Leeds


[Q]: Down syndrome is one of the most common chromosome abnormalities in humans . It occurs in about one per 1000 babies born each year . In 2015 , Down syndrome was present in 5.4 million individuals and resulted in 27,000 deaths down from 43,000 deaths in 1990 . It is named after John Langdon Down , the British doctor who fully described the syndrome in 1866 . Some aspects of the condition were described earlier by Jean - Étienne Dominique Esquirol in 1838 and Édouard Séguin in 1844 . In 1957 , the genetic cause of Down syndrome , an extra copy of chromosome 21 , was discovered .
[A]:
Down syndrome