In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Ex Input:
Question: The most frequent mechanism that induces the activation of the ABL protooncogene in chronic myeloid leukemia is: 
 Options:  <1> Point mutation <2> Gene amplification. <3> Methylation of the promoter. <4> Deletion <5> Translocation

Ex Output:
5


Ex Input:
Question: Acetyl-CoA: 
 Options:  <1> It is synthesized from pyruvate in the eukaryotic cytoplasm. <2> It has a phosphate bond rich in energy. <3> Presents a guanine nucleotide in coenzyme A. <4> Activates pyruvate carboxylase and inhibits pyruvate dehydrogenase. <5> It easily crosses the mitochondrial inner membrane.

Ex Output:
4


Ex Input:
Question: Which of the following strands of DNA has the same nucleotide sequence (except the change of T for U) as its primary transcript: 
 Options:  <1> The coding strand. <2> The mold thread. <3> The leading thread. <4> The delayed strand <5> Any.

Ex Output:

1