Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Q: Question: Do changes in basophil activation during grass-pollen sublingual immunotherapy correlate with clinical efficacy?
Answer: Allergen reactivity of peripheral blood basophils is not a biomarker for adverse events or early onset of clinical responses to SLIT.

A: no
****
Q: Question: Do lipopolysaccharide and cytokines inhibit rat cardiomyocyte contractility in vitro?
Answer: Prolonged exposure of ARVM to a mixture of LPS and inflammatory cytokines inhibits cell contractility. The effect is mediated by the inhibition of Ca(2+) influx via LTCC, and partially opposed by the inhibition of Na(+)/Ca(2+) exchange. Because both mechanisms are commonly seen in animal models of SIC, we conclude that prolonged challenge with Cytomix-100 of ARVM may represent an accurate in vitro model for SIC.

A: yes
****
Q: Question: Is iFN-alpha-2b-induced signal transduction and gene regulation in patient peripheral blood mononuclear cells enhanced by a dose increase from 5 to 10 megaunits/m2?
Answer: These results suggest that lower doses of IFN-alpha-2b are as effective as higher doses with respect to the induction of Janus-activated kinase-STAT signal transduction and the transcription of ISGs within immune effector cells.

A:
no
****