Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Q: You're in your office when you learn there's someone with a gun wandering outside. You can hear gunshots and screams. What do you do? That's the challenge for users of a new virtual reality program called SurviVR, designed to train employees how to deal with an active shooter situation in the workplace. The program works with HTC Vive, the virtual reality headset released earlier this year. An active shooter situation is when an armed person or people actively shoot in a small, populated area with the intention to kill. There were 20 such situations in the United States last year and 20 the year before, according to FBI statistics, resulting in a total of 231 deaths. This year saw the deadliest active shooter situation in US history , with 49 people killed in a nightclub in Orlando. In the training situation, users have four choices. They can lock themselves in the office. They can hide, perhaps in the office closet. They can run for an exit. Or they can use something in the office--a computer or a cup a pair of scissors-as a weapon to fight the shooter. This is an improvement on standard active shooter training. Gallo says, which typically teachers people to lock themselves in place and hide. The "lock down" method is often ineffective, he says, and has resulted in many deaths in recent years. In the training's basic level, no one gets killed. But as the trainings become more advanced, players who make a wrong choice be shot. There's no blood; the screen simply turns black slowly. If this sounds terrifying, that's the point, says Gallo. There are plenty of training programs to teach employees how to deal with workplace violence, sometimes involving role play with toy guns. But these trainings are basically games. Gallo says, with employees relaxed and even enjoying themselves. To teach people what they really need to know for an active shooter situation, they need to be scared. "SurviVR will take the fear and turn it into confidence." Gallo says.

A: What does Gallo think of the training programs involving role play with toy guns?
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Q: In yeast, the macromolecular complex Set1/COMPASS is capable of methylating H3K4, a posttranslational modification associated with actively transcribed genes. There is only one Set1 in yeast; yet in mammalian cells there are multiple H3K4 methylases, including Set1A/B, forming human COMPASS complexes, and MLL1-4, forming human COMPASS-like complexes. We have shown that Wdr82, which associates with chromatin in a histone H2B ubiquitination-dependent manner, is a specific component of Set1 complexes but not that of MLL1-4 complexes. RNA interference-mediated knockdown of Wdr82 results in a reduction in the H3K4 trimethylation levels, although these cells still possess active MLL complexes. Comprehensive in vitro enzymatic studies with Set1 and MLL complexes demonstrated that the Set1 complex is a more robust H3K4 trimethylase in vitro than the MLL complexes. Given our in vivo and in vitro observations, it appears that the human Set1 complex plays a more widespread role in H3K4 trimethylation than do the MLL complexes in mammalian cells.

A: Which is the histone residue methylated by MLL1?
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Q: One day, a brave jackal came to the river to drink some water. He saw a lion looking weak and tired, and asked, "What is the matter, King of the Jungle?" The lion told the jackal his story. The jackal felt sorry for the lion. He pulled and pulled at the lion's tail until the lion became free. The lion was very happy and said, "Thank you so much for helping me. I thought I would die! You are my friend for life! I would like you to come and live with me. From now on, I will hunt and share my food with you." The jackal moved in with the lion's family and had a wonderful time. Soon, the lion had children of his own and so did the jackal. The lioness was not happy about the friendship. She complained to her children. Her children complained to the jackal's children; the jackal's children complained to their mother and their mother complained to the jackal. The jackal was upset and told the lion, "You told me to live with you. If you don't like it any more, you should have said so yourself." The lion was shocked and said, "This is not true. I've never complained about you. I still want you to continue staying with me." The jackal said, "We understand each other. But our families don't. Perhaps it is better for us to live apart, but continue meeting each other when we are free. We can even hunt together!" The two families parted, but the lion and the jackal met often and remained friends for the rest of their lives. From the above paragraphs, we can conclude that in order to keep our good friendship, we have to give something up or give in in some particular cases. However, we can never give up or destroy our families. What do you think of it?

A:
How was the lion when the jackal first met him?
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