In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[EX Q]: Question: Which of these statements is NOT a characteristic of phase I clinical trials? 
 Options:  <1> They usually have non-therapeutic goals. <2> They can be done in healthy volunteers. <3> They can be done in patients. <4> They are usually randomized. <5> They are usually open.
[EX A]: 4

[EX Q]: Question: With regard to pyrogens and biotechnological medicines, it is possible to say: 
 Options:  <1> They have no tendency to aggregate or form large units with high molecular weight. <2> Ion exchange chromatography procedures (using their positive charge) can reduce endotoxin levels. <3> Ion exchange chromatography procedures (using their negative charge) can reduce endotoxin levels. <4> Ion exchange chromatography procedures (regardless of their charge) can reduce endotoxin levels. <5> They are unstable under standard autoclaving conditions.
[EX A]: 3

[EX Q]: Question: The gesture imitation test (Berger and Lézine, 1975) is an evaluation tool that is used in childhood, preferably to evaluate: 
 Options:  <1> Laterality <2> The body schema <3> Neural efficiency <4> Muscle tone <5> The motor.
[EX A]:
2