TASK DEFINITION: In this task, you are given a question and a context passage. You have to answer the question based on the given passage.
PROBLEM: What needs to decrease before pituitary growth hormone can increase in the blood?, Context: In addition to the negative consequences of sleep deprivation, sleep and the intertwined circadian system have been shown to have strong regulatory effects on immunological functions affecting both the innate and the adaptive immunity. First, during the early slow-wave-sleep stage, a sudden drop in blood levels of cortisol, epinephrine, and norepinephrine induce increased blood levels of the hormones leptin, pituitary growth hormone, and prolactin. These signals induce a pro-inflammatory state through the production of the pro-inflammatory cytokines interleukin-1, interleukin-12, TNF-alpha and IFN-gamma. These cytokines then stimulate immune functions such as immune cells activation, proliferation, and differentiation. It is during this time that undifferentiated, or less differentiated, like naïve and central memory T cells, peak (i.e. during a time of a slowly evolving adaptive immune response). In addition to these effects, the milieu of hormones produced at this time (leptin, pituitary growth hormone, and prolactin) support the interactions between APCs and T-cells, a shift of the Th1/Th2 cytokine balance towards one that supports Th1, an increase in overall Th cell proliferation, and naïve T cell migration to lymph nodes. This milieu is also thought to support the formation of long-lasting immune memory through the initiation of Th1 immune responses.

SOLUTION: cortisol, epinephrine, and norepinephrine

PROBLEM: When did some stores begin to go out of business due to the economy?, Context: The retail trade in Cork city includes a mix of both modern, state of the art shopping centres and family owned local shops. Department stores cater for all budgets, with expensive boutiques for one end of the market and high street stores also available. Shopping centres can be found in many of Cork's suburbs, including Blackpool, Ballincollig, Douglas, Ballyvolane, Wilton and Mahon Point. Others are available in the city centre. These include the recently[when?] completed development of two large malls The Cornmarket Centre on Cornmarket Street, and new the retail street called "Opera Lane" off St. Patrick's Street/Academy Street. The Grand Parade scheme, on the site of the former Capitol Cineplex, was planning-approved for 60,000 square feet (5,600 m2) of retail space, with work commencing in 2016. Cork's main shopping street is St. Patrick's Street and is the most expensive street in the country per sq. metre after Dublin's Grafton Street. As of 2015[update] this area has been impacted by the post-2008 downturn, with many retail spaces available for let.[citation needed] Other shopping areas in the city centre include Oliver Plunkett St. and Grand Parade. Cork is also home to some of the country's leading department stores with the foundations of shops such as Dunnes Stores and the former Roches Stores being laid in the city. Outside the city centre is Mahon Point Shopping Centre.

SOLUTION: 2008

PROBLEM: What is the most likely area a resource vanishes?, Context: In an effort to conserve water, Tucson is recharging groundwater supplies by running part of its share of CAP water into various open portions of local rivers to seep into their aquifer. Additional study is scheduled to determine the amount of water that is lost through evaporation from the open areas, especially during the summer. The City of Tucson already provides reclaimed water to its inhabitants, but it is only used for "applications such as irrigation, dust control, and industrial uses." These resources have been in place for more than 27 years, and deliver to over 900 locations.

SOLUTION:
open areas