Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does interferon responsiveness change in treatment-experienced hepatitis C subjects : implications for drug development and clinical decisions?
Answer: We contend that P/R-experienced subjects are represented within treatment-naive subjects. There are 2 important implications of this finding: (1) from a drug development perspective, a successful direct antiviral plus P/R therapy (IFN-based triple therapy) trial in P/R-experienced subjects may serve as supportive evidence in treatment-naive subjects; and (2) from a clinical decision perspective, previous P/R exposure should not alter new treatment decisions involving IFN-based triple therapy, as the IFN responsiveness to a second course of IFN is comparable.
no

Question: Does mPGES-2 deletion remarkably enhance liver injury in streptozotocin-treated mice via induction of GLUT2?
Answer: mPGES-2 deletion enhanced STZ-induced liver toxicity possibly via GLUT2-mediated STZ uptake, independently of diabetes mellitus.
yes

Question: Does a Pleiotropic Missense Variant in SLC39A8 be Associated With Crohn 's Disease and Human Gut Microbiome Composition?
Answer: Our results suggest that an SLC39A8-dependent shift in the gut microbiome could explain its pleiotropic effects on multiple complex diseases including CD.

yes