instruction:
Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
question:
Imatinib mesylate therapy in patients with gastrointestinal stromal tumors and impaired liver function.
answer:
non-adverse drug event


question:
Considerable improvement of myasthenic symptoms was seen in all patients within 3-6 months after the initiation of this therapy.
answer:
non-adverse drug event


question:
Spironolactone was continued, as serum creatinine and potassium levels were initially normal.
answer:

non-adverse drug event