Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Context: As elderly people go about their day in Manhattan, Harry walks along a sidewalk with his tabby cat Tonto on a leash, quoting Shakespeare's "King Lear" as he goes. Harry stops in at a grocer, buys some good food for his cat, and jokes that his sexual days are over.Next Harry meets his old friend Jacob on a bench, and tells him that his apartment building is being torn down to build a parking lot. Jacob complains about capitalists, and reassures Harry that he could always move in with him.On the way home, a kid tries to steal Harry's groceries and knocks him down. Harry is helped up by Leroy, his building super.Harry gets into his apartment and talks to Tonto, lamenting that he's been mugged four times in the past year, and that the whole city is getting run down.Some time later, police show up to forcibly remove Harry and his furniture from the building. Harry continues to spout "King Lear" while his son Burt arrives to pick him up.Harry goes to live with Burt and his wife and two grown sons in the suburbs. His younger grandson, Norman, has taken a vow of silence, leading to obvious tension with his brother and parents. Harry later asks Norman for the books that explain his beliefs.Harry goes back to his familiar bench to talk with Jacob, and they both agree it's been a long time since either has been with a woman. Jacob reminisces about his first sexual encounter with a servant girl when he was 14.Harry invites Leroy to dinner at Burt's house, and he plays the piano while Leroy dances to the tune. Leroy later comments that he lives with his 90-year-old mother and can't find a new job, which leads Burt's wife to question why Harry is not getting help from his two other kids.Knowing that he is a burden to Burt, Harry goes to look for his own apartment, but finds that the place he wants will not take cats. He then tells Burt he is going to Chicago to visit Shirley, Burt's sister, but before he leaves he stops at a city morgue to identify the body of Jacob, who has died with no relatives. Harry cries after recalling Jacob's story of losing his virginity.Burt takes Harry to the airport, but Harry soon learns that he can't go through security with Tonto, so he takes a cab to get a bus. Along the route, Harry asks the bus driver to stop so that Tonto can relieve himself, whereupon the cat runs away across a cemetery. The bus driver leaves Harry behind with his luggage, and when Tonto returns, Harry scolds him.Harry walks to a used car lot and buys an old Chevy for $250. He then checks into a motel and calls Burt to tell him what has happened, realizing in the process that his driver's license expired in 1958.Harry drives west rather slowly, with Tonto on the dashboard, recalling how he wanted to drive across the country when he was younger, but his wife and kids came along. He remembers they had many good times though. He confesses to Tonto that he has a great fear of pain, and that when he dies he would like to go quickly rather than the slow way his wife Annie died.Harry picks up two young hitchhikers, one of whom soon gets another ride, while the other a girl named Ginger continues west with Harry. She claims she is 16, and is running away from home to a commune in Boulder.Harry and Ginger get a motel for the night, and after she comes out of the bathroom half-naked, Harry is prompted to recall the first girl he loved, Jessie, whom he has not seen in 50 years. Ginger suggests that they go to see her, even though it's out of their way, and they eventually find her in a nursing home.At first Harry thinks Jessie remembers him, but her thoughts are marked by senility; she calls him Alex yet remembers his wife Annie. Then she suddenly asks Harry to dance, which they do while Ginger looks on.Harry 
 Question: Who is Harry's travelling companion?
tonto

Context: The Jack Sport was a French automobile manufactured from 1925 until 1930. 
 Question: What year was the end of Jack Sport?
1930

Context: Chronic myelogenous leukemia (CML) is a clonal hematopoietic disorder caused by the reciprocal translocation between chromosome 9 and 22. As a result of this translocation, a novel fusion gene, BCR-ABL, is created on Philadelphia (Ph) chromosome, and the constitutive activity of the BCR-ABL protein tyrosine kinase plays a critical role in the disease pathogenesis. Imatinib mesylate, a selective BCR-ABL tyrosine kinase inhibitor, was first given to a patient with CML in June 1998. Since then, it has continued to demonstrate remarkable efficacy in treating patients with CML. Based upon the results of early phase I and II studies, a phase III study (IRIS Study) that was randomized to first-line imatinib (400 mg/day) or to standard treatment with interferon+low-dose Ara-C, was conducted on 1,106 patients newly diagnosed (within 6 months) with chronic-phase CML. After median follow-up of 30 months, imatinib showed significantly superior tolerability, hematologic and cytogenetic responses (major cytogenetic response, 90%; complete cytogenetic response, 82%), and overall survival (95% without censoring allo-HSCT). Although imatinib is the first-line therapy and has changed the paradigm of CML treatment strategy, questions remain as to the meaning of cytogenetic and molecular response, curability, optimal dose, and relation with allo-HSCT. 
 Question: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?

bcr-abl