Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Q: Electronic book publishing has many of the same risks and opportunities as electronic music publishing. By delivering text direct to the user's computer screen, the e-book could cut down costs, and allow creators to deal directly with their audience, bypassing traditional publishers and readers. But it also raises the possibility of mass piracy . Phil Rance, founder and managing director of Online Originals, a London-based e-book publisher, sums it up. "No one wants Napster to happen to books." Indeed, the most popular MP3 have put the frighteners on an industry that generally operates some way behind the "bleeding edge". The Mata Group, a leading US-based market researcher, says publishers are far too concerned about protecting their rights, "We believe all the recent legal control over Napster is like putting a finger in a river that is already overflowing. Publishers need to deal with reality and come up with new ways to develop wide electronic distribution , asking the question: 'How can we use the certainty of wide distribution to our advantage?'" At the moment, most publishers would like to limit the use of e-books to the person who bought them, or to the computer used to download them. If that can be done, e-books become just an extra income stream in a publishing industry that would continue to operate the way it does today, according to Terry Robinson, business manager for Adobe's e-paper group. "If you've cracked digital rights aspect, you've cracked the market," he says. Robert Nichols, Books Director at BOL agrees, "Rights management is absolutely important. Publishers just say that 'until copyright is secure, we're not going to talk'."

A: What do publishers care most about e-books?
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Q: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a small vessel disease of the brain caused by mutations in the NOTCH3 gene. CADASIL progresses, in some cases, to subcortical dementia with a particular cognitive impairment. Different diseases in the dementia spectrum share a central cholinergic and sensorimotor plasticity alteration. We aimed to study different intracortical circuits and sensorimotor plasticity in CADASIL patients using transcranial magnetic stimulation protocols, and to determine whether these characteristics correlated with the results of clinical neuropsychological evaluation. Ten CADASIL patients and 10 healthy subjects were included in the study. All subjects underwent a transcranial magnetic stimulation study examining different intracortical circuits. Sensorimotor plasticity was also assessed using a paired associative stimulation and extensive neuropsychological tests. CADASIL patients showed a lack of intracortical facilitation, short latency afferent inhibition and sensorimotor plasticity when compared with control subjects. CADASIL patients also showed an altered neuropsychological profile. Correlation between sensorimotor plasticity and neuropsychological alterations was observed in CADASIL patients. These results suggest that acetylcholine and glutamate could be involved in the dementia process in CADASIL and that abnormal sensorimotor plasticity correlates with the neuropsychological profile in CADASIL patients.

A: Which gene is involved in CADASIL?
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Q: Minerals are everywhere! Scientists have identified more than 4,000 minerals in Earths crust, although the bulk of the planet is composed of just a few. A mineral possesses the following qualities: It must be solid. It must be crystalline, meaning it has a repeating arrangement of atoms. It must be naturally occurring. It must be inorganic. It must have a specific chemical composition. Minerals can be identified by their physical properties, such as hardness, color, luster (shininess), and odor. The most common laboratory technique used to identify a mineral is X-ray diffraction (XRD), a technique that involves shining an X-ray light on a sample, and observing how the light exiting the sample is bent. XRD is not useful in the field, however. The definition of a mineral is more restricted than you might think at first. For example, glass is made of sand, which is rich in the mineral quartz. But glass is not a mineral, because it is not crystalline. Instead, glass has a random assemblage of molecules. What about steel? Steel is made by mixing different metal minerals like iron, cobalt, chromium, vanadium, and molybdenum, but steel is not a mineral because it is made by humans and therefore is not naturally occurring. However, almost any rock you pick up is composed of minerals. Below we explore the qualities of minerals in more detail. Minerals are "crystalline" solids. A crystal is a solid in which the atoms are arranged in a regular, repeating pattern. Notice that in Figure 1.1 the green and purple spheres, representing sodium and chlorine, form a repeating pattern. In this case, they alternate in all directions. Sodium ions (purple balls) bond with chlo- ride ions (green balls) to make table salt (halite). All of the grains of salt that are in a salt shaker have this crystalline structure. Organic substances are the carbon-based compounds made by living creatures and include proteins, carbohydrates, and oils. Inorganic substances have a structure that is not characteristic of living bodies. Coal is made of plant and animal remains. Is it a mineral? Coal is a classified as a sedimentary rock, but is not a mineral. Minerals are made by natural processes, those that occur in or on Earth. A diamond created deep in Earths crust is a mineral, but a diamond made in a laboratory by humans is not. Be careful about buying a laboratory-made diamond for jewelry. It may look pretty, but its not a diamond and is not technically a mineral. Nearly all (98.5%) of Earths crust is made up of only eight elements - oxygen, silicon, aluminum, iron, calcium, sodium, potassium, and magnesium - and these are the elements that make up most minerals. All minerals have a specific chemical composition. The mineral silver is made up of only silver atoms and diamond is made only of carbon atoms, but most minerals are made up of chemical compounds. Each mineral has its own chemical formula. Table salt (also known as halite), pictured in Figure 1.1, is NaCl (sodium chloride). Quartz is always made of two oxygen atoms (red) bonded to a silicon atom (grey), represented by the chemical formula SiO2 (Figure 1.2). Quartz is made of two oxygen atoms (red) bonded to a silicon atom (grey). In nature, things are rarely as simple as in the lab, and so it should not come as a surprise that some minerals have a range of chemical compositions. One important example in Earth science is olivine, which always has silicon and oxygen as well as some iron and magnesium, (Mg, Fe)2 SiO4 . Some minerals can be identified with little more than the naked eye. We do this by examining the physical properties of the mineral in question, which include: Color: the color of the mineral. Streak: the color of the minerals powder (this is often different from the color of the whole mineral). Luster: shininess. Density: mass per volume, typically reported in "specific

A:
which of these is not a mineral characteristic?
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