instruction:
Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
question:
Question: Is plasminogen activation by fibroblasts from periodontal ligament and gingiva directly affected by chemokines in vitro?
Answer: These results suggest that plasminogen activation by PDL and GF is not directly affected by the chemokines even in the presence of the inflammatory mediators TGF-beta and IL-1.
answer:
no


question:
Question: Is the phenotypic predisposition of the parent in F1 hybrid correlated with transcriptome preference of the positive general combining ability parent?
Answer: The results revealed that the transcriptome profiles and DEGs in the F1s were highly related to phenotype bias to the positive GCA-effect parent. The transcriptome bias toward high GCA parents in F1 hybrids attributed to H3K36me3 modification both on global modification level and specific signaling pathways. Our results indicated the transcriptome profile and epigenetic modification level bias to high GCA parents could be the molecular basis of GCA.
answer:
yes


question:
Question: Does thermal microdebridement affect the time zero biomechanical properties of human patellar tendons?
Answer: Thermal microdebridement does not affect the biomechanical properties of cadaveric human patellar tendons at the time of initial treatment.
answer:

no