instruction:
Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
question:
Question: Is the G-308A variant of the Tumor Necrosis Factor-alpha ( TNF-alpha ) gene associated with obesity , insulin resistance and body fat distribution?
Answer: Our study did not detect any significant association of the G-308A TNFalpha polymorphism with obesity or with its clinical and metabolic abnormalities in this population. Our data suggests that, in our population, the G-308A TNFalpha polymorphism is unlikely to play a major role in the pathogenesis of these conditions.
answer:
no


question:
Question: Do dual inhibition of nuclear factor kappa-B and Mdm2 enhance the antitumor effect of radiation therapy for pancreatic cancer?
Answer: Combination therapy of radiation with nafamostat mesilate exerts enhanced anti-tumor effect against human pancreatic cancer.
answer:
yes


question:
Question: Does variation in the gene for human peroxisome proliferator activated receptor gamma ( PPARgamma ) play a major role in the development of morbid obesity?
Answer: Variation in the PPARgamma gene is unlikely to play a major role in the development of morbid obesity.
answer:

no