Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Q: Question: Does novel individual metabolic profile characterize the protein kinase B-alpha ( pkbα-/- ) in vivo model?
Answer: Specific metabolic characterization should be assessed individually. Therefore, our in silico model enables novel insights inaugurating specific primary preventive strategies targeting individual metabolic profiling precisely.

A: yes
****
Q: Question: Are biphasic redistribution of muscarinic receptor and the altered receptor phosphorylation and gene transcription underlying mechanisms in the rat heart during sepsis?
Answer: The m2AChR in the rat heart was externalized from light vesicles to sarcolemma (overexpression) during early sepsis but internalized from surface membranes to intracellular sites (underexpression) during late sepsis. Furthermore, changes in the receptor phosphorylation and gene transcription are responsible for the biphasic redistribution and the altered expression of m2AChR in the rat heart during the progression of sepsis.

A: yes
****
Q: Question: Are rigid sigmoidoscopy and MRI interchangeable in determining the position of rectal cancers?
Answer: 1) MRI and sigmoidoscopy are not interchangeable in determining the distance from anus to tumour simply by correcting for the length of the anal canal. It has not been determined if measurements from MRI or sigmoidoscopy are more accurate, but current evidence concerning the effect of neoadjuvant irradiation at different positions in the rectum is based upon rigid sigmoidoscopy. 2) The gain in tumour free distance above the anus induced by neoadjuvant treatment is small. Facilitation of sphincter-saving surgery should not be an argument for neoadjuvant treatment.

A:
no
****