Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does constitutive secretion of Interleukin-4 dictate CD133+ side population cells to resist drug treatment and cell death?
Answer: Our data suggest that the autocrine secretion of IL-4 is a potential target for the development of novel anticancer drugs to prevent the CSCs-mediated therapy failure and tumorigenesis.
yes

Question: Does nonresponse to pre-operative chemotherapy preclude long-term survival after liver resection in patients with colorectal liver metastases?
Answer: Liver resection offers a long-term survival benefit for patients with CRM, even when tumor growth proceeds during pre-operative chemotherapy.
no

Question: Does etanercept impair healing in rat models of tendon or metaphyseal bone injury?
Answer: Etanercept does not appear to impair tendon or metaphyseal bone healing to any substantial degree.

no