Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: CONCLUSION: Patients with insulin allergy may not have complete resolution of their symptoms after standard desensitization, particularly those patients with concomitant protamine allergy.
Example Output: adverse drug event

Example Input: At explant, all four systems had clots adherent to the surface of the tubing and connectors on the pump outflow side of the circuit.
Example Output: non-adverse drug event

Example Input: Mycophenolate mofetil-induced neutropenia in liver transplantation.
Example Output:
adverse drug event