In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Q: Paragraph: Background: Bacterial pneumonia (BP) is an inflammation of the lower airways and lung parenchyma secondary to bacterial infection. The pathogenesis of BP in dogs is complex and the role of canine respiratory viruses has not been fully evaluated. Objectives: The aim of this study was to investigate the occurrence of viral co-infections in dogs with BP and to assess demographic or clinical variables as well as disease severity associated with viral co-infections. Animals: Twenty household dogs with BP caused by opportunistic bacteria and 13 dogs with chronic (>30 days) tracheobronchitis caused by Bordetella bronchiseptica (BBTB). Methods: Prospective cross-sectional observational study. Diagnosis was confirmed by clinical and laboratory findings, diagnostic imaging, and cytologic and microbiologic analysis of bronchoalveolar lavage or transtracheal wash fluid. Canine parainfluenza virus (CPIV), canine adenovirus, canine herpes virus, canine influenzavirus, canine distemper virus, canine respiratory coronavirus (CRCoV) and canine pneumovirus, as well as B. bronchiseptica and Mycoplasma spp. were analyzed in respiratory samples using PCR assays. Results: CPIV was detected in 7/20 and CRCoV in 1/20 dogs with BP. Respiratory viruses were not detected in dogs with BBTB. There were no significant differences in clinical variables between BP dogs with and without a viral co-infection. Conclusion and Clinical Importance: Respiratory viruses were found frequently in dogs with BP and may therefore play an important role in the etiology and pathogenesis of BP. Clinical variables and disease severity did not differ between BP dogs with and without viral co-infection. 
 Title: Co-infections with Respiratory Viruses in Dogs with Bacterial Pneumonia

A: True
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Q: Paragraph: Absorption of neutral amino acids across the luminal membrane of intestinal enterocytes is mediated by the broad neutral amino acid transporter B 0 AT1 (SLC6A19). Its intestinal expression depends on co-expression of the membrane-anchored peptidase angiotensin converting enzyme 2 (ACE2) and is additionally enhanced by aminopeptidase N (CD13). We investigated in this study the expression of B 0 AT1 and its auxiliary peptidases as well as its transport function along the rat small intestine. Additionally, we tested its possible shortand long-term regulation by dietary proteins and amino acids. We showed by immunofluorescence that B 0 AT1, ACE2 and CD13 co-localize on the luminal membrane of small intestinal villi and by Western blotting that their protein expression increases in distal direction. Furthermore, we observed an elevated transport activity of the neutral amino acid L-isoleucine during the nocturnal active phase compared to the inactive one. Gastric emptying was delayed by intragastric application of an amino acid cocktail but we observed no acute dietary regulation of B 0 AT1 protein expression and L-isoleucine transport. Investigation of the chronic dietary regulation of B 0 AT1, ACE2 and CD13 by different diets revealed an increased B 0 AT1 protein expression under amino acid-supplemented diet in the proximal section but not in the distal one and for ACE2 protein expression a reverse localization of the effect. Dietary regulation for CD13 protein expression was not as distinct as for the two other proteins. Ring uptake experiments showed a tendency for increased L-isoleucine uptake under amino acid-supplemented diet and in vivo L-isoleucine absorption was more efficient under high protein and amino acid-supplemented diet. Additionally, plasma levels of branched-chain amino acids were elevated under high protein and amino acid diet. Taken together, our experiments did not reveal an acute amino acid-induced regulation of B 0 AT1 but revealed a chronic dietary adaptation mainly restricted to the proximal segment of the small intestine. 
 Title: Expression and regulation of the neutral amino acid transporter B 0 AT1 in rat small intestine

A: False
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Q: Paragraph: Individual-based epidemiology models are used to study the effects of public health interventions and changes in individual behavior to the dynamics of infectious diseases [1] . A detailed description of the individual-based model used in simulating the outbreaks in this study is presented in [2] . The individual-based model is made up of a dynamic social contact network and a disease transmission model. The social contact network which is a synthetic representation of a particular geographical region is generated using United States Census data. The structure of the underlying network is important since interactions between agents influences how disease propagates during epidemic simulations. In this initial study, neither changes in individual behavior nor intervention strategies are explored. However, in later studies to better understand the implications of specific intervention strategies, we would forecast disease dynamics given that effective measures have been introduced to control the spread of an outbreak. The construction of the dynamic social contact network requires two steps. In step 1 a synthetic population is created. Individuals in the synthetic population are tagged to realistic demographics while preserving the confidentiality of the original data sets. Each individual is assigned to a household using a decision tree based on demographic information (such as number of people in a household, number of children etc.) from data provided in SF3 and PUMA (Public Use Microdata Area) census files. Households are placed in realistic geographical regions. The synthetic population is statistically identical to the census aggregated at the block level. More information can be found in [3], [4] and [5]. Step 2 assigns a daily activity list with specified durations (start and end times) to each household based on several thousand responses to an activity or time-use survey. The activity templates which vary by region given factors such as the geographical location and age composition of the population, are created based on the National 
 Title: A Simulation Optimization Approach to Epidemic Forecasting Supporting Information Individual-based Model

A:
False
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