In this task, you are given a sentence in the Spanish language. Your task is to translate the Spanish sentence into the English language.

Example Input: La ruta de los fosfatos de pentosa produce
Example Output: The pentose phosphate pathway produces

Example Input: Con respecto a los tratamientos psicológicos efectivos para la depresión, se puede afirmar que
Example Output: With respect to effective psychological treatments for depression, it can be stated that

Example Input: Para estimar el aclaramiento plasmático de un fármaco (CLIR) que presenta un comportamiento cinético lineal y se excreta de forma significativa por la orina, en un paciente con insuficiencia renal (IR), es preciso conocer
Example Output:
To estimate the plasma clearance of a drug (CLIR) that presents a linear kinetic behavior and is excreted significantly in the urine, in a patient with renal failure (RI), it is necessary to know