Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: This was initially diagnosed as a spreading dental infection.
Example Output: non-adverse drug event

Example Input: We present a pediatric patient with leukemia and a severe, L-asparaginase-induced necrotizing pancreatitis, treated successfully with percutaneous drainage used to flush the infected necrotic parts.
Example Output: adverse drug event

Example Input: Cholesterol crystal embolization-associated renal failure after therapy with recombinant tissue-type plasminogen activator.
Example Output:
adverse drug event