In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

Input: Consider Input:  Overall , the phenotype observed in XHM - ED patients shows that the putative zinc - finger domain of NEMO has a regulatory function and demonstrates the definite requirement of CD40 - mediated NF - kappaB activation for B cell immunoglobulin class - switching .

Output: NF - kappaB


Input: Consider Input:  Lymphocyte glucocorticoid receptor binding in depression : normal values following recovery .

Output: glucocorticoid receptor


Input: Consider Input:  The results from the present study indicate that Smad3 , Smad4 , and Smad7 , at least in part , serve as mediators linking TGF - beta1 to transcriptional regulation of IgA switching related gene and regulation of IgA class switching .


Output: TGF - beta1