In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Example Input: Paragraph: Marine sponges and their associated bacteria have been proven to be a rich source of novel secondary metabolites with therapeutic usefulness in cancer, infection, and autoimmunity. In this study, 79 strains belonging to 20 genera of the order Actinomycetales and seven strains belonging to two genera of the order Sphingomonadales were cultivated from 18 different Caribbean sponges and identified by 16S rRNA gene sequencing. Seven of these strains are likely to represent novel species. Crude extracts from selected strains were found to exhibit protease inhibition against cathepsins B and L, rhodesain, and falcipain-2 as well as immunomodulatory activities such as induction of cytokine release by human peripheral blood mononuclear cells. These results highlight the significance of marine sponge-associated bacteria to produce bioactive secondary metabolites with therapeutic potential in the treatment of infectious diseases and disorders of the immune system. 
 Title: Anti-protease and Immunomodulatory Activities of Bacteria Associated with Caribbean Sponges
Example Output: False

Example Input: Paragraph: Interactions between the immune system and the central nervous system (CNS) constitute the most complex and interactive regulatory network in mammals. The high degree of specialization of cell types that comprise the CNS, and their intricate communication, controls both cognitive and vital functions. Disruption of the communication network and poor CNS regenerative properties make this organ vulnerable to microbial as well as physical injury. Although it is known that host responses must be strictly regulated to preserve CNS function and to minimize the incidence of autoimmunity, the factors regulating CNS immune and repair responses are not well understood. In addition to the absence of a dedicated lymphatic drainage system, CNS cells express few, if any, molecules encoded by the major histocompatibility complex (MHC) 1-3 . Therefore, in the quiescent CNS there is little endogenous antigen presentation or potential to activate T cells. Although the underlying basis for this limited immunological activity is not completely understood, interactions between both neurons and the glial population represented by microglia, astrocytes and oligodendrocytes (BOX 1), as well as constitutive secretion of neurotrophins and transforming growth factor-β, might contribute to this quiescent resting state 1,4-7 . The limited expression of adhesion molecules by endothelial cells of the blood-brain barrier (BBB) and the presence of tight junctions between these cells also limit or prevent large molecules, such as antibodies, and T cells from entering the CNS 2,8 . Despite this, a few activated/memory CD4 + and CD8 + T cells randomly patrol the CNS in the absence of 'danger' signals, and either exit or die in situ in the absence of antigen recognition 2,8 . Abstract | Several viruses infect the mammalian central nervous system (CNS), some with devastating consequences, others resulting in chronic or persistent infections associated with little or no overt pathology. Coronavirus infection of the murine CNS illustrates the contributions of both the innate immune response and specific host effector mechanisms that control virus replication in distinct CNS cell types. Despite T-cell-mediated control of acute virus infection, host regulatory mechanisms, probably designed to protect CNS integrity, contribute to the failure to eliminate virus. Distinct from cytolytic effector mechanisms expressed during acute infection, non-lytic humoral immunity prevails in suppressing infectious virus during persistence. 
 Title: Neurotrophins Coronavirus infection of the central nervous system: host-virus stand-off
Example Output: False

Example Input: Paragraph: The primary step for efficient control of viral diseases is the development of simple, rapid, and sensitive virus detection. Reverse transcription loop-mediated isothermal amplification (RT-LAMP) has been used to detect viral RNA molecules because of its simplicity and high sensitivity for a number of viruses. RT-LAMP for the detection of Potato virus X (PVX) was developed and compared with conventional reverse transcription polymerase chain reaction (RT-PCR) to demonstrate its advantages over RT-PCR. RT-LAMP reactions were conducted with or without a set of loop primers since one out of six primers showed PVX specificity. Based on real-time monitoring, RT-LAMP detected PVX around 30 min, compared to 120 min for RT-PCR. By adding a fluorescent reagent during the reaction, the extra step of visualization by gel electrophoresis was not necessary. RT-LAMP was conducted using simple inexpensive instruments and a regular incubator to evaluate whether RNA could be amplified at a constant temperature instead of using an expensive thermal cycler. This study shows the potential of RT-LAMP for the diagnosis of viral diseases and PVX epidemiology because of its simplicity and rapidness compared to RT-PCR. 
 Title: The Plant Pathology Journal Development of a Rapid Detection Method for Potato virus X by Reverse Tran- scription Loop-Mediated Isothermal Amplification
Example Output:
False