Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Input: Consider Input: Question: Does gPR39 activate proliferation and differentiation of porcine intramuscular preadipocytes through targeting the PI3K/AKT cell signaling pathway?
Answer: It indicated that GPR39 was a transducer of Zn(2+), and enhanced proliferation and differentiation of porcine intramuscular preadipocytes through activation of the PI3K/Akt signaling pathway.

Output: yes


Input: Consider Input: Question: Is retinol-binding protein-4 strongly associated with insulin sensitivity in normal pregnancies?
Answer: The increased fat mass and insulin resistance during normal pregnancy was best explained by measures of fat mass. However, the increase in RBP4 from early to late pregnancy, associated with a decline in insulin sensitivity, potentially indicates interactions with glucose metabolism.

Output: no


Input: Consider Input: Question: Does nanoencapsulation in lipid-core nanocapsules control mometasone furoate skin permeability rate and its penetration to the deeper skin layers?
Answer: This formulation is suitable for prolonged treatment of skin disorders which should avoid systemic absorption.


Output: yes