In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Example Input: Question: The simultaneous expression of IgM and IgD is observed for the first time in lymphocytes: 
 Options:  <1> Early Pro-B. <2> B mature. <3> Late Pro-B. <4> Pre-B. <5> B immature
Example Output: 2

Example Input: Question: Of the antiemetic drugs reviewed, in which of them their pharmacological activity is NOT related to dopaminergic receptors ?: 
 Options:  <1> Granisetron. <2> Cleboprida. <3> Droperidol <4> Tietilperazine. <5> Domperidone
Example Output: 1

Example Input: Question: What is the first level of organization of DNA in chromosomes': 
 Options:  <1> Histones. <2> Nucleosomes. <3> Sugar-phosphate chains. <4> Proteosomes <5> Nucleotides
Example Output:
2