Given scientific fact as input, generate the question from this fact such that it can be answered from the input.

Input: Consider Input: Respiratory acidosis is considered to be problematic because excess co2 in blood.

Output: Why is respiratory acidosis considered to be problematic?


Input: Consider Input: The tilt of earth on its axis is one factor that contributes to seasons occurring in new york state.

Output: What is one factor that contributes to seasons occurring in New York State?


Input: Consider Input: Calcium ion is an example of a second messenger.


Output: Calcium ion is an example of what kind of messenger?