You will be given a trivia clue, and the category it belongs to. You should answer with the best answer that belongs in the category and is described by the clue. For simplicity, answers should be in all lower cased letters.
--------
Question: Category: CAPITAL CITIES 
Clue: Home to the oldest cathedral & the oldest university in the Americas, this capital was founded in 1496

Answer: santo domingo


Question: Category: BESTSELLERS 
Clue: In the beginning this 2005 novel was simply titled "Forks"

Answer: twilight


Question: Category: HISTORIC STRUCTURES 
Clue: Pope Sixtus' death in 1590 ended his plan to convert this, still in Rome today, to a wool factory to employ city prostitutes

Answer:
the colosseum