In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Paragraph: Multiple sclerosis (MS) is a debilitating disease of the central nervous system (CNS) that has been extensively studied using the animal model experimental autoimmune encephalomyelitis (EAE). It is believed that CD4 + T lymphocytes play an important role in the pathogenesis of this disease by mediating the demyelination of neuronal axons via secretion of proinflammatory cytokines resulting in the clinical manifestations. Although a great deal of information has been gained in the last several decades about the cells involved in the inflammatory and disease mediating process, important questions have remained unanswered. It has long been held that initial neuroantigen presentation and T cell activation events occur in the immune periphery and then translocate to the CNS. However, an increasing body of evidence suggests that antigen (Ag) presentation might initiate within the CNS itself. Importantly, it has remained unresolved which antigen presenting cells (APCs) in the CNS are the first to acquire and present neuroantigens during EAE/MS to T cells, and what the conditions are under which this takes place, ie, whether this occurs in the healthy CNS or only during inflammatory conditions and what the related cytokine microenvironment is comprised of. In particular, the central role of interferon-g as a primary mediator of CNS pathology during EAE has been challenged by the emergence of Th17 cells producing interleukin-17. This review describes our current understanding of potential APCs in the CNS and the contribution of these and other CNS-resident cells to disease pathology. Additionally, we discuss the question of where Ag presentation is initiated and under what conditions neuroantigens are made available to APCs with special emphasis on which cytokines may be important in this process. 
 Title: The Critical Role of Antigen-Presentation-Induced Cytokine Crosstalk in the Central Nervous System in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis
True

Paragraph: To date, the SARS coronavirus is the only known highly pathogenic human coronavirus. In 2003, it was responsible for a large outbreak associated with a 10% fatality rate. This positive RNA virus encodes a large replicase polyprotein made up of 16 gene products (nsp1-16), amongst which two methyltransferases, nsp14 and nsp16, are involved in viral mRNA cap formation. The crystal structure of nsp16 is unknown. Nsp16 is an RNA-cap AdoMet-dependent (nucleoside-2 0 -O-)-methyltransferase that is only active in the presence of nsp10. In this paper, the expression, purification and crystallization of nsp10 in complex with nsp16 are reported. The crystals diffracted to a resolution of 1.9 Å resolution and crystal structure determination is in progress. 
 Title: Structural Biology and Crystallization Communications Crystallization and diffraction analysis of the SARS coronavirus nsp10-nsp16 complex
True

Paragraph: a b s t r a c t RFID technology meets identification and tracking requirements in healthcare environments with potential to speed up and increase reliability of involved processes. Due to this, high expectations for this integration have emerged, but hospital and medical centers interested in adoption of RFID technology require prior knowledge on how to squeeze RFID capabilities, real expectations and current challenges. In this paper, we show our lab tested solutions in two specific healthcare scenarios. On the one hand, we analyze the case of a medical equipment tracking system for healthcare facilities enabling both real-time location and theft prevention. Worth-noting aspects such as possible EMI interferences, technology selection and management of RFID data from hospital information system are analyzed. Lab testing of system reliability based on passive UHF RFID is provided for this case. On the other hand, we analyze and provide a solution for care and control of patients in a hospital based on passive HF RFID with the result of a fully functional demonstrator. Our prototype squeezes RFID features in order to provide a backup data source from patient's wristband. It also provides an offline working mode aiming to increase application reliability under network fail down and therefore, improving patient's safety. Considerations regarding lessons learned and challenges faced are exposed. 
 Title: Real-time location and inpatient care systems based on passive RFID

True