Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Input: Consider Input: Question: Is early reduction in number of T cells producing proinflammatory cytokines , observed after extracorporeal photopheresis , linked to apoptosis induction?
Answer: Since proinflammatory cytokines play a major role in the pathology of GvHD, their down-regulation post-ECP may produce a direct clinical benefit. The lowest number of IL2-, IFNgamma- and TNFalpha-expressing T cells occurred within the apoptotic population; however, Annexin V-negative T cells also demonstrated a marked reduction post-ECP. However, the lack of an increase in IL4 and IL10 expression indicates that this process was not a consequence of skewing toward a Th2 cytokine profile.

Output: no


Input: Consider Input: Question: Does myeloid knockout of HIF-1 α markedly affect hemorrhage/resuscitation-induced inflammation and hepatic injury?
Answer: Here, deleting HIF-1 α in myeloid cells and thereby in Kupffer cells was not protective after H/R. This data indicates that other factors, such as NF- κB, due to its upregulated phosphorylation in WT and KO mice, contrary to HIF-1 α, are rather key modulators of inflammation after H/R in our model.

Output: no


Input: Consider Input: Question: Do antibodies to trophoblast antigens HLA-G , placenta growth factor , and neuroD2 improve detection of circulating trophoblast cells in maternal blood?
Answer: The antibodies used in this study were unable to improve detection of trophoblast cells in the maternal circulation.


Output: no