Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Q: It is increasingly clear that the normal protein alpha-synuclein is in some manner closely associated with presynaptic components of select neuronal types within the adult human central nervous system (CNS) and, in addition, that in its pathologically altered state alpha-synuclein aggregates selectively in the form of filamentous inclusion bodies during certain progressive neurodegenerative disorders, such as familial and sporadic Parkinson's disease. By having the antibody AFshp raised specifically to alpha-synuclein to label Parkinson disease-specific Lewy bodies and Lewy neurites as well as synaptic boutons containing the unaltered protein, an initial attempt is made to map the overall distribution pattern and describe the staining behavior of the immunoreactive punctae in select regions of the prosencephalon. Neocortical immunolabeling is most prominent in the prodigious, but incompletely myelinated, association fields and faintest in the heavily myelinated primary motor and primary sensory fields, with the premotor and first order sensory association areas occupying an intermediate position. Of the thalamic grays evaluated, those containing powerfully myelinated fiber tracts (e.g. centrum medianum, habenular complex) show the weakest immunolabeling, whereas, less sturdily myelinated structures are highly immunoreactive. The fact that the immunostaining spectrum for normal alpha-synuclein is so broad, together with the fact that some thalamic sites actually are immunonegative leads to the following conclusions (1) alpha-synuclein, although present in the synaptic boutons of many nerve cells in the adult human CNS, is by no means ubiquitous there, and (2) neuronal types lacking the normal protein cannot generate the Parkinson's disease-specific filamentous pathology.

A: Against which protein is the antibody used for immonostaining of Lewy bodies raised?
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Q: Do you know of anyone who uses the truth to deceive ? When someone tells you something that is true, but leaves out important information that should be included, he can give you a false picture. For example, some might say, "I just won a hundred dollars on the lottery . It was great. I took that dollar ticket back to the store and turned it in for one hundred dollars!" This guy's a winner, right? Maybe, maybe not. We then discover that he bought $200 worth of tickets, and only one was a winner. He's really a big loser! www. .com He didn't say anything that was false, but he left out important information on purpose. That's called a half-truth. Half-truths are not technically lies, but they are just as dishonest. Some politicians often use this trick. Let's say that during Governor Smith's last term, her state lost one million jobs and gained three million jobs. Then she seeked another term. One of her opponents said, "During Governor Smith's term, the state lost one million jobs!" That's true. However, an honest statement would have been, "During Governor Smith's term, the state had a net gain of two million jobs." Advertisers will sometimes use half-truths. It's against the law to make false statements so they try to mislead you with the truth. An advertisement might say, "Nine out of ten doctors advised their patients to take Yucky Pills to cure toothache." It fails to mention that they only asked ten doctors and nine of them work for the Yucky Company. This kind of deception happens too often. Lies are lies, and sometimes the truth can lie as well, which is a sad fact of life.

A: How much did the lottery winner lose?
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Q: Converging plates create the worlds largest mountain ranges. Each combination of plate types continent- continent, continent-ocean, and ocean-ocean creates mountains. Two converging continental plates smash upwards to create gigantic mountain ranges (Figure 1.1). Stresses from this uplift cause folds, reverse faults, and thrust faults, which allow the crust to rise upwards. As was stated previously there is currently no mountain range of this type in the western U.S., but we can find one where India is pushing into Eurasia. (a) The worlds highest mountain range, the Himalayas, is growing from the colli- sion between the Indian and the Eurasian plates. (b) The crumpling of the Indian and Eurasian plates of continental crust creates the Himalayas. Subduction of oceanic lithosphere at convergent plate boundaries also builds mountain ranges. This happens on continental crust, as in the Andes Mountains (Figure 1.2), or on oceanic crust, as with the Aleutian Islands, which we visited earlier. The Cascades Mountains of the western U.S. are also created this way. The Andes Mountains are a chain of con- tinental arc volcanoes that build up as the Nazca Plate subducts beneath the South American Plate. Amazingly, even divergence can create mountain ranges. When tensional stresses pull crust apart, it breaks into blocks that slide up and drop down along normal faults. The result is alternating mountains and valleys, known as a basin-and-range (Figure 1.3). In basin-and-range, some blocks are uplifted to form ranges, known as horsts, and some are down-dropped to form basins, known as grabens. (a) Horsts and grabens. (b) Mountains in Nevada are of classic basin-and-range form. Click image to the left or use the URL below. URL: Click image to the left or use the URL below. URL:

A:
the indian plate and eurasian plate converge to make this mountain range.
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