In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Ex Input:
Question: In a determination of the activity of an enzyme, the depletion of the substrate: 
 Options:  <1> It is essential for most trials. <2> It may give falsely low results in sera with high enzymatic activity. <3> It occurs when the reagent is finished. <4> It occurs due to a defect in the spectrophotometer. <5> It can lead to falsely elevated results in sera with high enzymatic activity.

Ex Output:
2


Ex Input:
Question: The tissue is avascular: 
 Options:  <1> Epithelial. <2> Conjunctive. <3> Osseous. <4> Muscular. <5> Nervous.

Ex Output:
1


Ex Input:
Question: The terpene that contains 10 carbon atoms and is derived from two isoprene units is called: 
 Options:  <1> Diterpene <2> Monoterpene <3> Sesquiterpene <4> Triterpene <5> Meroterpeno.

Ex Output:

2