Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
Iatrogenic hypercalcemia due to vitamin D3 ointment (1,24(OH)2D3) combined with thiazide diuretics in a case of psoriasis.

Ex Output:
adverse drug event


Ex Input:
Clinicians should be vigilant when monitoring for cardiotoxicity in patients receiving pentamidine throughout the duration of therapy.

Ex Output:
adverse drug event


Ex Input:
Within 24 hours of fluid restriction and cessation of desmopressin, her symptoms and hyponatremia resolved.

Ex Output:

adverse drug event