Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Input: Consider Input: Question: Does extended pattern prostate biopsy minimize the volume-grade bias in prostate cancer detection?
Answer: Although more high grade cancers are detected with extended pattern biopsy, there is no differential upgrading with respect to prostate volume. Based on these observations extended prostate sampling in trials of agents that decrease prostate volume would have minimal impact on volume-grade associations.

Output: no


Input: Consider Input: Question: Are flavones from Erythrina falcata modulators of fear memory?
Answer: Our results demonstrate that vitexin, isovitexin and diosmetin-6-C-glucoside and flavonoidic fractions resulted in a significant retention of fear memory but did not prevent the extinction of fear memory. These results further substantiate that the treatment with pure flavonoids or flavanoid-rich fractions might represent potential therapeutic approaches for the treatment of neurocognitive disorders, improvement of memory acquisition and spontaneous recovery of fear.

Output: yes


Input: Consider Input: Question: Does allogenicity of cryopreserved human fibroblasts : cryopreservation downregulate the allogenicity of fibroblasts making up the matrices of allografts?
Answer: Our study suggests that although the fibroblast cell component may be beneficial in restoring allograft function properties initially, it may render the implanted allograft more immunogenic, ultimately resulting in greater rejection and inflammatory responses by the host and, in turn, degeneration of the graft.


Output: no