Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[Q]: The Nimrud ivories are carved ivory plaques and figures dating from the 9th to the 7th centuries BC that were excavated from the Assyrian city of Nimrud (in modern Ninawa in Iraq) during the 19th and 20th centuries.
[A]: What is the surface of Nimrud ivories made of?


[Q]: Fish species are expected to shrink in size by up to 24% because of global warming, say scientists. The scientists argue that failure to control greenhouse gas emissions will have a greater effect on marine ecosystems than previously thought. Previous research has suggested that changing ocean temperatures would affect both the distribution and the reproductive abilities of many species of fish. This new work suggests that fish size would also be heavily affected. The researchers built a model to see how fish would react to lower levels of oxygen in the water. As ocean temperatures increase, so do the body temperatures of fish. But, according to lead author, Dr William Cheung, from the University of British Columbia, the lower level of oxygen in the water is key. Warmer waters could decrease ocean oxygen levels and greatly reduce fish body weight. On the other hand, rising temperatures directly increase the metabolic rate of the fish's body function. This leads to an increase in oxygen demand for normal body activities. So the fish will run out of oxygen for growth at a smaller body size. The research team also used its model to predict fish movements as a result of warming waters. The group believes that most fish populations will move towards the Earth's poles at a rate of up to 35km per decade. "So in, say, the North Sea," says Dr Cheung," one would expect to see more smaller-body fish from tropical waters in the future." Taking these factors into consideration, the research team concludes that fish body size will shrink between 14% and 24%, with the largest decreases in the Indian and Atlantic oceans. When compared with actual observations of fish sizes, the model seems to _ what's actually happening in the seas. The researchers looked at two case studies involving North Atlantic cod and haddock. They found that recorded data on these fish showed greater decreases in body size than the models had predicted. Dr Alan Baudron, from the University of Aberdeen, UK, believes smaller-sized fish could seriously affect the ability of fish to reproduce. "Smaller fish produce fewer and smaller eggs which could affect the reproductive potential of fish stocks," he said.
[A]: What is the key factor making the fish smaller now?


[Q]: Specific outcomes upon activation of the c-Jun N-terminal kinase (JNK) pathway critically depend on the intensity and duration of signal transmission. Dual-specificity phosphatases (DUSPs) play a very important role in these events by modulating the extent of JNK phosphorylation and activation and thus regulating cellular responses to stress. M3/6 (DUSP8) is one of the dual-specificity protein phosphatases with distinct specificity towards JNK. It has been shown that M3/6 itself is phosphorylated by JNK upon stimulation with arsenite, but the role of this phosphorylation has not been investigated. In this study, we mapped JNK-induced phosphorylation sites on M3/6 using mass spectrometry. Phosphorylated residues Ser 515, Thr 518 and Ser 520 were identified and site-directed mutagenesis was employed to investigate their role. Upon arsenite stimulation, M3/6 mutated at these sites exhibited decreased phosphorylation compared to the wild-type protein. No difference was observed in terms of the enzyme's in vitro phosphatase activity, its substrate specificity towards JNK isoforms, its interactions with JNK and the scaffold family of JNK-interacting proteins (JIPs), its stability or its subcellular localization. Interestingly, expression of M3/6 phosphorylation mutants delayed the time-course of JNK phosphorylation and activation by arsenite. We propose that phosphorylation of the M3/6 phosphatase by JNK in response to stress stimuli results in attenuation of phosphatase activity and acceleration of JNK activation.
[A]:
Which protein is affected by dusp8 activation?