TASK DEFINITION: In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
PROBLEM: Paragraph: During viral entry, enveloped viruses require the fusion of their lipid envelope with host cell membranes. For coronaviruses, this critical step is governed by the virally-encoded spike (S) protein, a class I viral fusion protein that has several unique features. Coronavirus entry is unusual in that it is often biphasic in nature, and can occur at or near the cell surface or in late endosomes. Recent advances in structural, biochemical and molecular biology of the coronavirus S protein has shed light on the intricacies of coronavirus entry, in particular the molecular triggers of coronavirus S-mediated membrane fusion. Furthermore, characterization of the coronavirus fusion peptide (FP), the segment of the fusion protein that inserts to a target lipid bilayer during membrane fusion, has revealed its particular attributes which imparts some of the unusual properties of the S protein, such as Ca 2+ -dependency. These unusual characteristics can explain at least in part the biphasic nature of coronavirus entry. In this review, using severe acute respiratory syndrome coronavirus (SARS-CoV) as model virus, we give an overview of advances in research on the coronavirus fusion peptide with an emphasis on its role and properties within the biological context of host cell entry. 
 Title: Physiological and molecular triggers for SARS-CoV membrane fusion and entry into host cells

SOLUTION: True

PROBLEM: Paragraph: To ensure the safety of wastewater reuse for irrigation of food crops and drinking water pathogenic viruses must be reduced to levels that pose no significant risk. To achieve this goal minimum reduction of viruses by treatment trains have been suggested. For use of edible crops a 6-log reduction and for production of potable drinking water a 12-log reduction has been suggested. These reductions were based on assuming infective virus concentrations of 10 5 to 10 6 per liter. Recent application of molecular methods suggests that some pathogenic viruses may be occurring in concentrations of 10 7 to 10 9 per liter. Factors influencing these levels include the development of molecular methods for virus detection, emergence of newly recognized viruses, decrease in per capita water use due to conservation measures, and outbreaks. Since neither cell culture nor molecular methods can assess all the potentially infectious virus in wastewater conservative estimates should be used to assess the virus load in untreated wastewater. This review indicates that an additional 2-to 3-log reduction of viruses above current recommendations may be needed to ensure the safety of recycled water. Information is needed on peak loading of viruses. In addition, more virus groups need to be quantified using better methods of virus quantification, including more accurate methods for measuring viral infectivity in order to better quantify risks from viruses in recycled water. 
 Title: How much reduction of virus is needed for recycled water: A continuous changing need for assessment?

SOLUTION: False

PROBLEM: Paragraph: Context: The 2-1-1 helpline is a social services innovation that has spread rapidly throughout the U.S. Policy diffusion theory suggests that policymakers seek to reduce uncertainty by anticipating the effects of a proposed innovation through tools such as cost-benefıt analyses. Few policy diffusion studies have examined use of information, such as cost-benefıt analyses, in the diffusion process. The purpose of this study is to examine how cost-benefıt analyses were used during the rapid diffusion of 2-1-1 across states. The paper also describes components of 2-1-1 cost-benefıt analyses. Evidence acquisition: In 2011, cost-benefıt analyses of 2-1-1 and substantive citations of them were identifıed through scholarly key word searches using Academic Search Premier and Web of Science, general Internet searches using Google search terms, and communications with academicians and 2-1-1 practitioners through personal contact and e-mail discussion groups. To be included in this study, documents had to be related to 2-1-1 helplines, present information about their costs and benefıts, and be formal documents. The documents were catalogued and analyzed for costbenefıt analyses or references to analyses, and stated purpose. Evidence synthesis: Of the 19 documents that met eligibility inclusion criteria, nine were original cost-benefıt analyses and ten referenced analyses conducted for other jurisdictions. The diffusion of2-1-1 helplinesin the U.S.hasbeen influenced by interjurisdictionalexchange of cost-benefıt analyses, in both the creation of original analyses and/or the referencing of previous work. (Am J Prev Med 2012;43(6S5):S497-S505) Am J Prev Med 2012;43(6S5):S497-S505 S497 S498 Shank / Am J Prev Med 2012;43(6S5):S497-S505 www.ajpmonline.org S502 Shank / Am J Prev Med 2012;43(6S5):S497-S505 www.ajpmonline.org 
 Title: A Review of the Role of Cost-Benefit Analyses in 2-1-1 Diffusion

SOLUTION:
True