Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: DESIGN: Description of the clinical findings in two patients with this condition.

Output: non-adverse drug event


Input: Consider Input: In patients with cirrhosis, the metabolism of meperidine is decreased, leading to accumulation of the parent drug and possible CNS depressive effects similar to hepatic encephalopathy.

Output: adverse drug event


Input: Consider Input: A week before the onset of hepatitis, the patient complained of upper gastrointestinal symptoms and was treated for gastritis.


Output: non-adverse drug event