In medical studies, the efficacy of medical treatments (called interventions) is evaluated within a group of study participants. You will be given a sentence of a study report in which your task is to list the phrases that describe the intervention(s) of the study. You should list the phrase in the same order that they appear in the text, separated by commas. If no information about the interventions is mentioned, just answer with "not found". Interventions are: a specific drug, surgery, talking therapy, a lifestyle modification, control or placebo treatment. Do not include details, dosages, frequency and duration, intervention mentions that are not in an informative span of text.
--------
Question: Prior adjuvant chemotherapy was permitted .

Answer: not found


Question: Development of renal disease in people at high cardiovascular risk : results of the HOPE randomized study .

Answer: not found


Question: Quantitative muscle strength testing sum scores declined in both treatment groups , -0.2 % for methotrexate and -3.4 % for placebo ( 95 % confidence interval = -2.5 % to +9.1 % for difference ) .

Answer:
methotrexate, placebo