instruction:
In this task, you are given a set of context paragraph and some supporting facts to answer a question. Your task is to generate answer for given question based on set of context paragraphs and supporting facts.
question:
Context_1 : Estrogen (American English) or oestrogen (British English) is the primary female sex hormone as well as a medication. It is responsible for the development and regulation of the female reproductive system and secondary sex characteristics. "Estrogen" may also refer to any substance, natural or synthetic, that mimics the effects of the natural hormone. The estrane steroid estradiol is the most potent and prevalent endogenous estrogen, although several metabolites of estradiol also have estrogenic hormonal activity. Estrogens are used as medications as part of some oral contraceptives, in hormone replacement therapy for postmenopausal, hypogonadal, and transgender women, and in the treatment of certain hormone-sensitive cancers like prostate cancer and breast cancer. They are one of three types of sex hormones, the others being androgens/anabolic steroids like testosterone and progestogens like progesterone. Context_2 : The sex hormone receptors, or sex steroid receptors, are a group of steroid hormone receptors that interact with the sex hormones, the androgens, estrogens, and progestogens. They include the: Context_3 : Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estrone. Levels of estriol in women who are not pregnant are almost undetectable. However, during pregnancy, estriol is synthesized in very high quantities by the placenta and is the most produced estrogen in the body by far, although circulating levels of estriol are similar to those of other estrogens due to a relatively high rate of metabolism and excretion. Relative to estradiol, both estriol and estrone have far weaker activity as estrogens. Although it is less commonly used than other estrogens, estriol is available for medical use throughout the world in a variety of formulations, including for oral and vaginal administration. Context_4 : Estradiol (E2), also spelled oestradiol, is a steroid, an estrogen, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues such as the breasts, uterus, and vagina during puberty, adulthood, and pregnancy, but it also has important effects in many other tissues, including bone, fat, skin, liver, and the brain. While estrogen levels in men are lower compared to those in women, estrogens have essential functions in men, as well. It is found in most vertebrates and crustaceans, insects, fish, and other animal species. Context_5 : Sex steroids, also known as gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors. Their effects are mediated by slow genomic mechanisms through nuclear receptors as well as by fast nongenomic mechanisms through membrane-associated receptors and signaling cascades. The term sex hormone is nearly always synonymous with "sex steroid". The polypeptide hormones luteinizing hormone, follicle-stimulating hormone and gonadotropin-releasing hormone are usually not regarded as sex hormones, although they play major sex-related roles. Context_6 : Female sex tourism is sex tourism by women who travel intending to engage in sexual activities with a sex worker. Female sex tourists may seek aspects of the sexual relationship not shared by their male counterpart, such as perceived romance and intimacy. Women – especially wealthy, single, older white women – plan their holidays to have romance and sex with a companion who knows how to make them feel special and give them attention. The prevalence of female sex tourism is significantly lower than male sex tourism. Context_7 : G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the "GPER" gene. GPER binds to and is activated by the female sex hormone estradiol and is responsible for some of the rapid effects that estradiol has on cells. Context_8 : Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estriol. Estrone, as well as the other estrogens, are synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue. Relative to estradiol, both estrone and estriol have far weaker activity as estrogens. Previously, estrone was available as an injected estrogen for medical use, but it is now no longer marketed. Context_9 : Pregnenolone acetate (brand names Antofin, Previsone, Pregno-Pan), also known as pregn-5-en-3β-ol-20-one 3β-acetate, is a synthetic pregnane steroid and an ester of pregnenolone which is described as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. It has been found to significantly reduce wrinkles in elderly women when applied in the form of a 0.5% topical cream, effects which were suggested to be due to improved hydration of the skin. Pregnenolone acetate has been marketed in France in a topical cream containing 1% pregnenolone acetate and 10% "sex hormone" for the treatment of premature skin aging but was withdrawn from the market in 1992. Although the drug has been described by some sources as a glucocorticoid, other authors have stated that systemic pregnenolone acetate has no undesirable metabolic or toxic effects even at high dosages. Context_10 : Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. Via its indirect action, following an initial surge the production of sex hormones (Androgen and Estrogen) tapers off. fact_1 : Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. fact_2 :  Via its indirect action, following an initial surge the production of sex hormones (Androgen and Estrogen) tapers off. fact_3 : Estrogen (American English) or oestrogen (British English) is the primary female sex hormone as well as a medication. Question: Which female sex hormone, is Deslorelin acetate known to taper off?
answer:
Estrogen


question:
Context_1 : (German: Der Hund von Baskerville) is a 1929 German silent mystery film directed by Richard Oswald and starring Carlyle Blackwell, Alexander Murski, Livio Pavanelli. The film is an adaptation of the Sherlock Holmes novel "The Hound of the Baskervilles" by Arthur Conan Doyle. It was the last Sherlock Holmes adaptation in the silent film era. Context_2 : The Leopard is a crime novel by Norwegian novelist, Jo Nesbø. Its Norwegian title is "Panserhjerte", which does not directly translate to The Leopard; it rather means something along the lines of "armoured heart". Moreover, "leopard" refers to the stealthy tread of the killer in the book, while "armoured heart" is what Harry Hole himself gains by his experiences. "Panserhjerte" is also a Norwegian term for Constrictive pericarditis. "The Leopard" is the eighth novel featuring Nesbø's crime detective, Inspector Harry Hole. Context_3 : Oliver Marc "Olli" Schulz (born 15 October 1973 in Hamburg) is a German singer-songwriter, actor and presenter. He became known as a singer and guitarist of the indie rock group Olli Schulz & der Hund Marie and as sidekick for Joko and Klaas in their television programs like Circus HalliGalli. In 2016 his TV show "Schulz & Böhmermann" started along with fellow presenter Jan Böhmermann, with whom he also presents the weekly podcast show "Fest & Flauschig" (Firm & Fluffy) on Spotify. He is also active as a solo musician. His current album, "Feelings aus der Asche", peaked at #4 at the German album charts. Context_4 : The Bear of the Baskervilles (German:Der Bär von Baskerville) is a 1915 German silent film directed by Harry Piel. Context_5 : The Hound of the Baskervilles (German:Der Hund von Baskerville ) is a 1937 German mystery film directed by Carl Lamac and starring Bruno Güttner, Fritz Odemar and Peter Voß. It is an adaptation of the Sherlock Holmes's story "The Hound of the Baskervilles" by Arthur Conan Doyle. Context_6 : Der Hund von Baskerville is a 1914 German silent film adaptation of Arthur Conan Doyle's "The Hound of the Baskervilles". This was the first film adaptation of the famed Conan Doyle novel. According to the website silentera.com, the film was considered lost, but has been rediscovered; the Russian Gosfilmofond film archive possesses a print, while the Filmmuseum München has a 35mm positive print. Context_7 : The Hound of Florence: A Novel (German: "Der Hund von Florenz" ) is a 1923 novel written by Felix Salten. It is best known today for partly inspiring the 1959 Walt Disney Pictures film, "The Shaggy Dog", as well as a sequel and remakes. The novel was first translated into English in 1930 by Huntley Paterson, and the translation has illustrations by Kurt Wiese. Context_8 : "The Dog and the Sparrow" is a story by the Brothers Grimm, told in their book "Kinder- und Hausmärchen" as KHM58. The original name is "Der Hund und der Sperling". Context_9 : Phantom is a crime novel by Norwegian novelist Jo Nesbø, published jn 2012. Its Norwegian title is "Gjenferd", which does not directly translate to "Phantom"; rather it translates to a word similar to "ghosts". "Phantom" is the ninth novel featuring crime detective Inspector Harry Hole. Context_10 : The Hound of the Baskervilles is the third of the crime novels written by Sir Arthur Conan Doyle featuring the detective Sherlock Holmes. Originally serialised in "The Strand Magazine" from August 1901 to April 1902, it is set largely on Dartmoor in Devon in England's West Country and tells the story of an attempted murder inspired by the legend of a fearsome, diabolical hound of supernatural origin. Sherlock Holmes and his companion Dr. Watson investigate the case. This was the first appearance of Holmes since his apparent death in "The Final Problem", and the success of "The Hound of the Baskervilles" led to the character's eventual revival. fact_1 : Der Hund von Baskerville is a 1914 German silent film adaptation of Arthur Conan Doyle's "The Hound of the Baskervilles". fact_2 : The Hound of the Baskervilles is the third of the crime novels written by Sir Arthur Conan Doyle featuring the detective Sherlock Holmes. Question: Der Hund von Baskerville is an adaptation of a crime novel featuring what detective?
answer:
Sherlock Holmes


question:
Context_1 : Spanish nationality law refers to all the laws of Spain concerning nationality. Article 11 of the First Title of the Spanish Constitution refers to Spanish nationality and establishes that a separate law is to regulate how it is acquired and lost. This separate law is the Spanish Civil Code. In general terms, Spanish nationality is based on the principle of "jus sanguinis", although limited provisions exist for the acquisition of Spanish nationality based on the principle of "jus soli". Context_2 : Demolition Man is an EP released by A&M on September 21, 1993 (United States) and November 1, 1993 (UK) in support of the Sylvester Stallone/Wesley Snipes film "Demolition Man". It features Sting's re-recording of The Police track "Demolition Man", as well as several live recordings. The live recordings were recorded at Villa Manin, Codroipo, Italy on 25 July 1993. The US and International/European EP release features the title track and five live recordings and sales for this release were listed on the US Albums Chart, as the UK release was a standard single which featured an exclusive single version of the title track as well as the album version and two live recordings. The UK release charted therefore on the UK Singles Chart, where it peaked at number 21. Context_3 : Flippin' Out is an album by Gigolo Aunts released in October 1993 on Fire Records in the UK and April 1994 on RCA/BMG in the US. It includes the track "Where I Find My Heaven", featured on the soundtrack to 1994 comedy film, "Dumb and Dumber", which helped to break the band into the charts. The US and UK versions feature different track listings. The title track, "Flippin' Out", was originally recorded by the Wizards, a NY/NJ supergroup circa 1988/1989, part of a six song EP that was never released. In a story attributed to Phil Marino, known for his work photographing the band, the Gigolo Aunts became acquainted with the song through Rob Norris, the producer of their debut album, "Everybody Happy". Norris, a former member of the Bongos and at the time a current member of the Wizards, reportedly sent a tape of the six song EP to the Gigolo Aunts, who recorded "Flippin' Out" as the title track for the album. The album cover features Chloë Sevigny. Context_4 : The National Health is the fourth studio album by English indie rock band Maxïmo Park. It was released in the United Kingdom on 11 June 2012 by V2 Records. The album was the first by the band to feature a title track. The one-minute opening track, a ballad with piano and strings, has been noted by the band as a deliberate move to disorientate the listener (previous albums have all begun with a fast-paced track, like the title track, The National Health). Context_5 : Carl Heinrich Maria Orff (] ; (1895--)10 1895 – (1982--)29 1982 ) was a German composer, best known for his cantata "Carmina Burana" (1937). In addition to his career as a composer, Orff developed an influential approach toward music education for children. Context_6 : Javed Ali (Hindi: जावेद अली , Urdu: ‎ , born 5 July 1982) is an Indian playback singer who has been singing in Hindi movies since the year 2000. In 2007 Javed Ali came into limelight for his song "Ek Din Teri Raahon Mein" from the film "Naqaab" and thereafter he sang "Jashn-e-Bahaaran" from Jodhaa Akbar, "Arziyan" from Delhi-6, "Kun Faya Kun" from Rockstar, "Guzarish" from Ghajini, "Aa Jao Meri Tamanna" from Ajab Prem Ki Ghazab Kahani, "Gale Lag Ja" from De Dana Dan, "Tu Hi Haqeeqat" from Tum Mile, "Tum Tak" from Raanjhanaa, Jab Tak Hai Jaan title track from the film Jab Tak Hai Jaan, Ishaqzaade title track from the film Ishaqzaade, "Galat Baat Hai" from Main Tera Hero, Daawat-e-Ishq film's Title Track, "Maula" from Wazir, Nagada Nagada from Jab We Met, "Tu Jo Mila" from Bajrangi Bhaijaan etc & many more. He is doing playback singing in various languages like Hindi, Bengali, Odia, Kannada, Tamil, Telugu, Marathi and Assamese. He judged reality shows like Sa Re Ga Ma Pa L'il Champs 2011 on Zee TV and Great Music Gurukul on Colors Bangla. Javed Ali Hosted Zee TV's Singing Reality Show Sa Re Ga Ma Pa 2012. Context_7 : Walking on Sunshine is the title track of the critically acclaimed 1978 album by Reggae and Soca artist Eddy Grant on the Parlophone music label. It was the follow-up to his 1977 album "Message Man". It features the hits singles, 'Living On The Front Line' and the title track. The former introduced Grant to the mainstream in the UK in 1979, peaking at number 11 in the charts while the latter was Grant's debut in the lower reaches of the US R&B charts (#86). Context_8 : The Mass is an album released in 2003 by Eric Lévi's musical project Era. It is Era's third album. It achieved success in several European countries. The title track, "The Mass", is an adaptation of O Fortuna, a classical piece by Carl Orff. Context_9 : Some People Change is the fifth studio album by the American country music duo Montgomery Gentry. It was released by Columbia Records Nashville on October 24, 2006. Certified gold in the United States, the album produced three singles on the "Billboard" Hot Country Songs charts: the title track (previously cut by Kenny Chesney on his 2004 album "When the Sun Goes Down"), "Lucky Man", and "What Do Ya Think About That". The title track was a number seven hit on the Hot Country Songs charts, while "Lucky Man" became the duo's third Number One hit, and "What Do Ya Think About That" reached number three. Context_10 : "In Our Lifetime" is a funk song recorded by singer Marvin Gaye, issued on his final Motown album, 1981's "In Our Lifetime". The title track's rhythm admittedly was taken from Rick James while the song parlayed a different message of partying with Marvin predicting the world's end as he had believed from teachings he absorbed from his father that Armageddon was approaching and that he wondered if it would happen in his lifetime. He says the title track as a question mark. In fact, the original concept of the album was to have a question mark at the end of the album title, "In Our Lifetime?", Motown instead took the question mark rush-releasing the album after it was presented to the label in late 1980 by bassist Frank Blair. The song ends ironically enough in a much somber jazz tone that was likely edited in by Motown staff. An earlier funk version of the song was recorded as "I Offer You Nothing But Love" for Marvin's "Love Man" album and a 2007 Odyssey Studios mix of the song ended the song without a jazz instrumental. fact_1 : The Mass is an album released in 2003 by Eric Lévi's musical project Era. fact_2 :  The title track, "The Mass", is an adaptation of O Fortuna, a classical piece by Carl Orff. fact_3 : Carl Heinrich Maria Orff (] ; (1895--)10 1895 – (1982--)29 1982 ) was a German composer, best known for his cantata "Carmina Burana" (1937). Question: What was the nationality of the man who the title track of The Mass was based on?
answer:

German