In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Example Input: Question: In response to an increase in the concentration of adrenaline and circulating glucagon: 
 Options:  <1> It activates the phosphorylation of glycogen phosphorylase and the degradation of glycogen. <2> It increases the intracellular concentration of cAMP, and therefore, the synthesis of glycogen. <3> It decreases the intracellular concentration of cAMP and the degradation of glycogen. <4> The phosphorylation of glycogen synthase and glycogen synthesis is activated. <5> Increases the intracellular concentration of ATP and glycogenesis.
Example Output: 1

Example Input: Question: If after establishing the confidence interval with respect to a difference between two independent means, we find that the zero value is not in the interval: 
 Options:  <1> We can not make any decision regarding the null hypothesis of equality of means. <2> We can not reject the null hypothesis of equality between population means. <3> We must reject the null hypothesis of equality between population means. <4> We accept the null hypothesis of equality between the population means. <5> We reject the alternative hypothesis of equality between population means.
Example Output: 3

Example Input: Question: What do we mean when a doctor believes firmly in his treatment, even though controlled studies have proven ineffective, the results obtained with it will be better, his patients will be better, and will have more patients? 
 Options:  <1> The opposing process of Solomon. <2> The floor effect. <3> The Asher Paradox <4> The effect of contemplation of Prochaska. <5> The theory of the control door.
Example Output:
3