instruction:
In this task, you are given a set of context paragraph and some supporting facts to answer a question. Your task is to generate answer for given question based on set of context paragraphs and supporting facts.
question:
Context_1 : Estrogen (American English) or oestrogen (British English) is the primary female sex hormone as well as a medication. It is responsible for the development and regulation of the female reproductive system and secondary sex characteristics. "Estrogen" may also refer to any substance, natural or synthetic, that mimics the effects of the natural hormone. The estrane steroid estradiol is the most potent and prevalent endogenous estrogen, although several metabolites of estradiol also have estrogenic hormonal activity. Estrogens are used as medications as part of some oral contraceptives, in hormone replacement therapy for postmenopausal, hypogonadal, and transgender women, and in the treatment of certain hormone-sensitive cancers like prostate cancer and breast cancer. They are one of three types of sex hormones, the others being androgens/anabolic steroids like testosterone and progestogens like progesterone. Context_2 : The sex hormone receptors, or sex steroid receptors, are a group of steroid hormone receptors that interact with the sex hormones, the androgens, estrogens, and progestogens. They include the: Context_3 : Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estrone. Levels of estriol in women who are not pregnant are almost undetectable. However, during pregnancy, estriol is synthesized in very high quantities by the placenta and is the most produced estrogen in the body by far, although circulating levels of estriol are similar to those of other estrogens due to a relatively high rate of metabolism and excretion. Relative to estradiol, both estriol and estrone have far weaker activity as estrogens. Although it is less commonly used than other estrogens, estriol is available for medical use throughout the world in a variety of formulations, including for oral and vaginal administration. Context_4 : Estradiol (E2), also spelled oestradiol, is a steroid, an estrogen, and the primary female sex hormone. It is named for and is important in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is essential for the development and maintenance of female reproductive tissues such as the breasts, uterus, and vagina during puberty, adulthood, and pregnancy, but it also has important effects in many other tissues, including bone, fat, skin, liver, and the brain. While estrogen levels in men are lower compared to those in women, estrogens have essential functions in men, as well. It is found in most vertebrates and crustaceans, insects, fish, and other animal species. Context_5 : Sex steroids, also known as gonadocorticoids and gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors. Their effects are mediated by slow genomic mechanisms through nuclear receptors as well as by fast nongenomic mechanisms through membrane-associated receptors and signaling cascades. The term sex hormone is nearly always synonymous with "sex steroid". The polypeptide hormones luteinizing hormone, follicle-stimulating hormone and gonadotropin-releasing hormone are usually not regarded as sex hormones, although they play major sex-related roles. Context_6 : Female sex tourism is sex tourism by women who travel intending to engage in sexual activities with a sex worker. Female sex tourists may seek aspects of the sexual relationship not shared by their male counterpart, such as perceived romance and intimacy. Women – especially wealthy, single, older white women – plan their holidays to have romance and sex with a companion who knows how to make them feel special and give them attention. The prevalence of female sex tourism is significantly lower than male sex tourism. Context_7 : G protein-coupled estrogen receptor 1 (GPER), also known as G protein-coupled receptor 30 (GPR30), is a protein that in humans is encoded by the "GPER" gene. GPER binds to and is activated by the female sex hormone estradiol and is responsible for some of the rapid effects that estradiol has on cells. Context_8 : Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estriol. Estrone, as well as the other estrogens, are synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue. Relative to estradiol, both estrone and estriol have far weaker activity as estrogens. Previously, estrone was available as an injected estrogen for medical use, but it is now no longer marketed. Context_9 : Pregnenolone acetate (brand names Antofin, Previsone, Pregno-Pan), also known as pregn-5-en-3β-ol-20-one 3β-acetate, is a synthetic pregnane steroid and an ester of pregnenolone which is described as a glucocorticoid and as a skin-conditioning and skin anti-aging agent. It has been found to significantly reduce wrinkles in elderly women when applied in the form of a 0.5% topical cream, effects which were suggested to be due to improved hydration of the skin. Pregnenolone acetate has been marketed in France in a topical cream containing 1% pregnenolone acetate and 10% "sex hormone" for the treatment of premature skin aging but was withdrawn from the market in 1992. Although the drug has been described by some sources as a glucocorticoid, other authors have stated that systemic pregnenolone acetate has no undesirable metabolic or toxic effects even at high dosages. Context_10 : Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. Via its indirect action, following an initial surge the production of sex hormones (Androgen and Estrogen) tapers off. fact_1 : Deslorelin acetate is an injectable gonadotropin releasing hormone super-agonist (GnRH agonist) also known as an LHRH agonist. fact_2 :  Via its indirect action, following an initial surge the production of sex hormones (Androgen and Estrogen) tapers off. fact_3 : Estrogen (American English) or oestrogen (British English) is the primary female sex hormone as well as a medication. Question: Which female sex hormone, is Deslorelin acetate known to taper off?
answer:
Estrogen


question:
Context_1 : Eastlands is Tasmania's largest shopping centre, located on the eastern side of the Derwent River, situated in the shopping district of Rosny Park, within the greater area of Hobart, Tasmania, Australia. It has a gross lettable area of about 33,000 square metres. Context_2 : Polegate is a village and civil parish in the Wealden District of East Sussex, England, United Kingdom. It is located five miles (8 km) north of the seaside resort of Eastbourne and is part of the greater area of that town. Although once a railway settlement, its importance as such has now waned by route closures. The civil parish of Polegate had a population of 8,586 on the 2011 census, 41.2% aged 65 and over. Context_3 : A metropolitan area, sometimes referred to as a metro area, greater area, commuter belt or conurbation, is a region consisting of a densely populated urban core and its less-populated surrounding territories, sharing industry, infrastructure, and housing. Context_4 : WCBC is an AM radio station that serves the greater area of Cumberland, Maryland. Founded in April, 1976, WCBC provides news coverage: locally, regionally, and nationally; weather forecasts; participation in major community events to promote the area and its organizations by way of remote broadcasts and community service announcements. Context_5 : The Biltmore is an upscale residential neighborhood & financial district in central North East Phoenix, Arizona. It is the city's most acclaimed neighborhood, largely due to its location, near the Arizona Biltmore Hotel. The local landmark was opened on 23 February 1929. The Resort is surrounded by two 18 hole championship golf courses built in 1928 and 1977 along with some of the most exclusive homes in the Valley of the Sun. The greater area is known as a financial district surrounded by upscale shopping, dining, and for its quality of life. The financial district is clustered with business and residential mid-rise tower buildings and gated neighborhoods along a line known as the "Camelback Corridor" which extends from Central Avenue, East on Camelback Road into Scottsdale. Context_6 : Hegang (, also known as Haoli and Heligang), is a prefecture-level city in Heilongjiang province of the People's Republic of China, situated in the southeastern section of the Lesser Khingan Range, facing Jiamusi across the Songhua River to the south and Russia's Jewish Autonomous Oblast across the Amur River to the north. Hegang is one of the principal coal-producing cities in China. Hegang covers an administrative area of 14679.88 km² and according to the 2010 Census, has a population of 1,058,665 inhabitants. Its built-up area is home to 664,471 inhabitants spread out over 5 urban districts including Dongshan being urbanized, even though still largely rural. Context_7 : Arbroath Infirmary is a hospital serving the town of Arbroath and the greater area of Angus, Scotland. Arbroath has a population of over 36,000 and the greater area served is over 60,000. The hospital is situated at the top of Rosemount Road and is part of NHS Tayside. It is separated into two wings. The Queen Mother wing hosts the maternity, minor injuries unit and outpatient department. The main wing consists of the medical unit with a female and a male medical ward, a physiotherapy gym and the X-ray department. There is also a kitchen in the main wing with a dining room. The operating theatre is no longer in use but is located in the main wing. There is no accident and emergency department in this hospital. Context_8 : New Town Road is a link road that connects Elizabeth Street to the Main Road within the greater area of Hobart, Tasmania. This road has seen less usage since the construction of the Brooker Highway which allows traffic to move directly to the main road and onto the northern area of the state. Context_9 : Vanga (vɑːɳɢ/ə/) is a city in Bandundu Province in the Democratic Republic of the Congo, approximately 340 km east of the capital city Kinshasa. Vanga is in the Kwilu District in the Bulungu Territory. Vanga is known for its large medical center that supports the greater Bandundu region. The greater area is considered a "citè" surrounding the hospital. Context_10 : Pulandian District () is one of the seven districts under the administration of Dalian, located in the south of Liaoning province, People's Republic of China. Its area is 2769.90 km² and its permanent population as of 2010 is 741,230. The district borders the prefecture-level city of Yingkou to the north. fact_1 :  Hegang covers an administrative area of 14679.88 km² and according to the 2010 Census, has a population of 1,058,665 inhabitants. fact_2 :  Its area is 2769.90 km² and its permanent population as of 2010 is 741,230. Question: Which has a greater area, Hegang or Pulandian District?
answer:
Hegang


question:
Context_1 : Selima Salaun was raised in Algeria and Tunisia before attending school and becoming an opticienne-lunetière (licensed as optician, optometrist, and optical artisan) in France. After working in Paris for Royale Optique and Alain Mikli, Salaun landed in New York City to manage Mikli’s first New York store. Foregoing the launch of Mikli’s first store in Japan, the first Selima Optique boutique was opened in 1993 on the corner of Wooster and Broome in Soho. The Optique began fulfilling custom orders with a French atelier when a friend (Hubert Kriegel of the Timeless Ride) asked if Selima could make him a “funkier” version of the iconic “Le Corbusier” frame. After Barney’s president bought a few customs, the store asked to carry a full brand collection and, with some wholesale guidance from Barneys, the first official Selima Optique collection was produced and sold through a shop-in-shop at Barneys New York in 1996. Since 1996 the company has expanded with retail locations and wholesale accounts across the world and into different industries as well. In the 2000s there was Selima’s Soho lingerie store “Le Corset,” French-inspired luxury lingerie shopped by New Yorkers and worn by Baby Spice in the Rolling Stone Magazine. And in 2009 there was “Hats by Selima Atelier,” a collection of eclectic hats created with partner Virginie Promeyrat and notably shopped by Madonna. Now, Selima Optique has retail locations in New York, Los Angeles, Dallas, and Paris, France and its collection is wholesaled globally. The brand has collaborated with the likes of Jack Spade and J.Crew, and more recently with NBA MVP Russell Westbrook, style icon Iris Apfel, and New York’s Neue Galerie. Personally, Selima Salaun has helped mentor designers like Darylynn and Coco & Breezy while sitting on the Council of Fashion Designers of America’s board and helping found the Eyewear Designers of the Council of Fashion Designers of America (efCFDA). Popular with celebrities and creatives, Selima’s clients include Anne Hathaway, Lady Gaga, and Ryan Gosling. Client-turned-friend John Turturro credits her as the inspiration for the character played by Sofia Vergara in his film “Fading Gigolo.” Context_2 : Jessica Simpson's The Price of Beauty is an American documentary reality series that followed singer Jessica Simpson and her two best friends Ken Pavés and CaCee Cobb as they traveled worldwide "to meet women, study local fashions, dietary fads and beauty regimes," all in an attempt to explore the meaning of true beauty in different cultures. It was Simpson's return to the reality television genre that had made her a star six years earlier on MTV's "". Simpson also sang the official theme song, entitled "Who We Are". Context_3 : The Jessica Simpson Collection is a fashion line of clothing and other items for women and juniors. Besides clothing, the brand also includes handbags, sunglasses, accessories, jewellery, shoes and fragrances. The brand initially launched in 2006 as a shoe collaboration with Nine West co-founder Vince Camuto. Due to the success that followed, Simpson began adding on, which resulted in the brand's current 22 different licenses. Context_4 : L.A.M.B. was a fashion line by American singer Gwen Stefani, the lead vocalist of the rock band No Doubt. The line manufactured apparel and fashion accessories. It was founded in 2003 and made its runway debut in 2004. The fashion line manufactured accessories like shoes, watches, bags and a fragrance called "L." The name is an acronym of her debut solo album "Love. Angel. Music. Baby". Context_5 : Lubica Kucerova (born 27 April 1983), also known as Lubica Slovak, is a Slovakia born fashion designer, Ryerson University graduate and founder of LUBICA, clothing company based in Jamaica. Lubica's early childhood influence was her grandmother who was a seamstress. She debuted her self-titled fashion line "Lubica" in Toronto at the LG Fashion Week in 2005 and has created several collections under her brand: Blue, Bliss, Bloom, Toucan, Trinity, Beyond and Dream. The Lubica line includes bikinis, resort contemporary women's wear wear and is inspired by the tropics. Lubica is also recognized for her partnership with international recording artist Tami Chynn in opening a female boutique named "Belle" in Kingston, Jamaica and also their collaboration in designing the award-winning Anuna collection. Context_6 : Ashley Nicolle Ross (née Simpson; born October 3, 1984), known by the stage name Ashlee Simpson, is an American singer-songwriter and actress. The younger sister of pop singer and actress Jessica Simpson, Ashlee began appearing in television commercials at the age of 15. She later pursued a career as an actress, and had a recurring role on the family drama "7th Heaven". Her breakout came following her appearance on the reality show "" (2003–05), which focused on her sister Jessica and her then-husband Nick Lachey. While working on her debut studio album, Simpson became the star of her own spin-off reality series, "The Ashlee Simpson Show" (2004–05). The show became a ratings hit, and earned Simpson widespread recognition. Like her sister before her, Simpson became the center of considerable media attention, much of which focused on her relationship with musician Ryan Cabrera. Context_7 : Playlist: The Very Best of Jessica Simpson is the first greatest hits album recorded by American singer Jessica Simpson. It was released on October 12, 2010 by Epic Records and Legacy Recordings. The album was released in the United Kingdom as The Collection with two bonus tracks. Context_8 : Nine West (also 9 West) is an American fashion wholesale and retail company. The corporate headquarters are located in White Plains, New York. Context_9 : John Vincent "Vince" Camuto (June 4, 1936 – January 21, 2015) was an American women’s footwear designer and shoe industry executive, best known for co-founding the women's fashion brand Nine West. Following the 1999 sale of Nine West to Jones Apparel Group for $900 million, Camuto became CEO and Chief Creative Officer of a new fashion company, Camuto Group, maker of the Jessica Simpson brand. Context_10 : "My Only Wish" is a holiday song written by Jessica Simpson, Aaron Pearce and Christopher Stewart, recorded by American singer-songwriter Jessica Simpson. It was released by Primary Wave Records on November 22, 2010 as the lead single from her seventh studio album, "Happy Christmas". The track received mixed reviews from music critics, with some commentators criticizing the song's close similarity to past hit "All I Want for Christmas is You". It premiered at On Air with Ryan Seacrest and the official Jessica Simpson website, jessicasimpson.com, on November 11, 2010. Simpson also notably allowed the song's free distribution on iTunes for several months. fact_1 : The Jessica Simpson Collection is a fashion line of clothing and other items for women and juniors. fact_2 :  The brand initially launched in 2006 as a shoe collaboration with Nine West co-founder Vince Camuto. fact_3 : Nine West (also 9 West) is an American fashion wholesale and retail company. fact_4 :  The corporate headquarters are located in White Plains, New York. Question: The Jessica Simpson Collection is a fashion line  initially launched as a shoe collaboration with an American fashion wholesale and retail company headquartered where?
answer:

White Plains, New York