Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
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Question: Context: The film opens in Tokyo, where 27-year-old office worker Taeko Okajima, is planning to take a 10-day vacation. Having previously visited her sister's husband's farm in Yamagata. She had a good time there before, and has decided to go back again.As she prepares for her trip, her mind drifts back to her youth, when she was 10-years-old. After school lets out, almost all of Taeko's classmates have interesting places they are going to go to, but Taeko does not. When she brings this up to her family, they suggest that Taeko go with the family's Grandmother to a hot springs resort.Taeko eagerly goes with her Grandmother, but finds herself bored when all her Grandmother wishes to do is relax in their room. Taeko goes exploring the myriad baths in the resort by herself, but due to either the overwhelming beauty of one bath (or the heat of the baths), she passes out.While packing, she receives a call from her older sister whose husband owns the farm, and they have a laugh over the past incident.On her way to the train to the farm, Taeko passes by a fruit stand, and is reminded of when the family received a pineapple.This also happened during her 10th year, and she recalls how almost noone knew how to properly cut it. Her father decreed that it would not be touched until it was found out, and a few days later, one of Taeko's sister finds out. There is much eagerness once it is sliced into pieces, but slowly, the family quickly discerns they do not like its taste. Taeko attempts to stomach the pieces she has, and her sisters give her their pieces. In the end, the family concluded that the banana is the "king of fruits."Making it to the train station, Taeko also recalls more about the year 1966, when she was 10-years-old. With the popularity of the Beatles in full-swing, her sisters became enamored with the trends of the time. Her sister Nanako was in art school, and kept up with trends, including wearing a mini-skirt. Her other sister Yaeko had a small crush on an actress in a female acting troupe. However, while her sisters remember these things fondly, Taeko recalls she was too young to really get into these trends like her older sisters.One day after showing her Mother her grades, her Mother finds leftovers from her lunch, and expresses her disappointment in her daughter being picky, and not finishing her food. The next day at lunch, she is sitting next to a boy who is fine with finishing the radish and onion portion of his meal, but dislikes finishing his milk (per school rules, a student can only leave one item to be thrown away from their meal). Taeko offers to give him her radish and onions, and she'll finish his milk. The two quickly make a trade, but Taeko quickly finds that though she has no problems drinking milk, there's a bit too much for her to enjoy a second bowl.Afterwards, Taeko and several of her friends take part in a classroom debate. The topics cover everything from running in the halls, to handling leftovers. Not much is done regarding the issues, and there is much bickering and yelling.After remembering these things, the adult Taeko boards her train for the farm.Once aboard, her memories shift back to an encounter, where three girls from another class gigglingly inform her that a boy in their class named Hirota likes her. Taeko has no idea who Hirota, and her friends show her some graffiti near the school, showing Taeko and Hirota's name under an umbrella-like drawing. Her friends do some research, and find out that Hirota is a good pitcher for his classroom's baseball team.One day, both Taeko and Hirota's classes are pitted against each other in a baseball game.Hirota's female classmates eagerly chant that Taeko is watching, and Taeko's friends cheer for their own homeroom team, in defiance of the other girls. During the game, the cold gets to Takeko, and she rushes for the 
 Question: What city was Taeko traveling to?

Answer: yamagata.


Question: Context: Facioscapulohumeral muscular dystrophy (FSHD) is one of the most prevalent adult muscular dystrophies. The common clinical signs usually appear during the second decade of life but when the first molecular dysregulations occur is still unknown. Our aim was to determine whether molecular dysregulations can be identified during FSHD fetal muscle development. We compared muscle biopsies derived from FSHD1 fetuses and the cells derived from some of these biopsies with biopsies and cells derived from control fetuses. We mainly focus on DUX4 isoform expression because the expression of DUX4 has been confirmed in both FSHD cells and biopsies by several laboratories. We measured DUX4 isoform expression by using qRT-PCR in fetal FSHD1 myotubes treated or not with an shRNA directed against DUX4 mRNA. We also analyzed DUX4 downstream target gene expression in myotubes and fetal or adult FSHD1 and control quadriceps biopsies. We show that both DUX4-FL isoforms are already expressed in FSHD1 myotubes. Interestingly, DUX4-FL expression level is much lower in trapezius than in quadriceps myotubes, which is confirmed by the level of expression of DUX4 downstream genes. We observed that TRIM43 and MBD3L2 are already overexpressed in FSHD1 fetal quadriceps biopsies, at similar levels to those observed in adult FSHD1 quadriceps biopsies. These results indicate that molecular markers of the disease are already expressed during fetal life, thus opening a new field of investigation for mechanisms leading to FSHD. 
 Question: Which disease is associated with the ectopic expression of the protein encoded by the gene DUX4?

Answer: fshd


Question: Context: Three men, Red Pollard (Tobey Maguire), Charles S. Howard (Jeff Bridges), and Tom Smith (Chris Cooper) come together as the principal jockey, owner, and trainer of the championship horse Seabiscuit, rising from troubled times to achieve fame and success through their association with the horse. Red is the child of a Canadian family financially ruined by the Great Depression. In desperate need of money, the family leaves Red with a horse trainer. Red eventually becomes a jockey, but makes extra money through illegal boxing matches which left him blind in one eye. Howard is a clerk in a bicycle shop who gets asked by a passing motorist to repair his automobile, a technology which has recently been introduced. As a result, Howard becomes knowledgeable enough with automobiles to increase their performance and sell them as a dealer, eventually becoming the largest car dealer in California and one of the Bay Area's richest men. However, his son is killed in an automobile accident while driving the family car, which sends Howard into a bout of deep depression, which eventually results in his wife (Valerie Mahaffey) leaving him. On a trip to Mexico to obtain a divorce and to drown his sorrows, he meets Marcela Zabala (Elizabeth Banks). Marcela helps Howard overcome his depression, mainly through horse-riding. After marrying Marcela, Howard acquires a stable of horses and later has a chance encounter with the skilled and kindly horse trainer and drifter Smith. Howard hires Smith to manage his stables after Smith, who specializes in rehabilitating injured and abused horses, explains to Howard "You don't throw a whole life away just 'cause it's banged up a little bit". Smith convinces Howard to acquire the colt "Seabiscuit", who comes from noted lineage but had been deemed "incorrigible" by past handlers and was later broken and trained to lose against better horses. Smith is unable to find a jockey willing to deal with Seabiscuit's temperament, but after witnessing Red Pollard brawling with other stable boys, he sees in him a similar temperament to the feisty horse and decides to appoint him as Seabiscuit's jockey. Seabiscuit and Pollard become close and they begin to race. After overcoming early difficulties, such as a dismissive media and Pollard's anger issues and blind eye, Seabiscuit begins to earn considerable success and becomes an extremely popular underdog for the millions affected by the Great Depression. Inspired, Howard tries repeatedly to provoke a race with the mocking New York tycoon Samuel Riddle and his fearsome stallion "War Admiral", the top race horse in the country. Riddle eventually relents to a match race on his terms between War Admiral and Seabiscuit, but while the date approaches, Pollard is injured in a riding accident, fracturing his leg. When the doctor reports that he will be unable to ride again, Red suggests that Howard get an old friend, the successful jockey George Woolf (Gary Stevens) to be Seabiscuit's new rider. Red teaches Woolf about Seabiscuit's handling and mannerisms. At the match race, Seabiscuit upsets the heavy favorite, War Admiral, partly because of a secret that Pollard relates to Woolf, instructing him to hold him head to head with the other horse so he gets "a good look at the Admiral." Later on, Seabiscuit is racing at Santa Anita when he is injured and has to stop. Red helps him to recover and get fit enough to race again. The last race is again at the Santa Anita, and Red rides him this time after putting a special self-made brace on his own leg to keep it stable. Woolf is on a different horse. Seabiscuit drops to last place and trails the pack, but Woolf holds back to be alongside Red and let Seabiscuit "get a good look". After a short conversation, Seabiscuit surges and wins the race. Red says, "You know, everyone thinks that we found this broken down horse and fixed him, but we didn't. He fixed us. Every one of us. And I guess in a way, we kinda fixed each other, too." 
 Question: How does Red almost go blind in one eye?

Answer:
boxing