Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
Although the t-AML developed following oral etoposide therapy, the child had previously received high-dose, multiagent chemotherapy, and rearrangement of the MLL gene was not demonstrated.

Ex Output:
adverse drug event


Ex Input:
The patient suffered a life-threatening anaphylactoid reaction to amifostine.

Ex Output:
adverse drug event


Ex Input:
The mortality rate has been estimated at about 10%.

Ex Output:

non-adverse drug event