Write a fact related to the given fact, based on the given topic word. Note that, your fact should have at least one word in common with the given fact. All facts in this task refer to scientific facts. Your related fact must form a chain with the given fact. Chains form when two facts connect together to produce the third fact. An example of a chain is: "pesticides cause pollution" (given fact) + "pollution can harm animals" (related fact) → "pesticides can harm animals" (connected chain). Avoid creating simple paraphrases of the given fact. While your generated fact should be related to the input fact, they must describe slightly different scientific phenomena. It's okay if your related fact includes some irrelevant information, provided that it has some overlap with the given fact and it contains some words corresponding to the provided topic.

[Q]: Fact: Nephrons are the structural and functional units of the kidneys. 
Topic: kidney urine.
[A]: Normally the kidneys manufacture urine.


[Q]: Fact: the number of rings in a tree trunk can be used to estimate the age of the tree. 
Topic: rings tree trunk.
[A]: EXOGENOUS: Growing by additions on the outside, such as the rings of a tree trunk.


[Q]: Fact: threatening behavior causes a fight-or-flight response in animals. 
Topic: controls fight-or-flight response.
[A]:
Fear also causes adrenaline to surge, which is part of the fight or flight response.