In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Input: Consider Input: Question: If you want to study the efficacy and safety of a new cytostatic for a specific oncological process and, at the same time, contrast the efficacy that adds a new monoclonal antibody to this treatment, what would be the most appropriate study design? 
 Options:  <1> Parallel test. <2> Cross test <3> Factorial test. <4> Sequential test. <5> Test of n = 1.

Output: 3


Input: Consider Input: Question: To calculate the number of different genotypes in any allelic series the formula is applied: 
 Options:  <1> (n-1) / 2. <2> n x (n + 1) / 2. <3> n x (n-1) / 2. <4> (n-1) x (n + 1) / 2. <5> (2n-1) / 2.

Output: 2


Input: Consider Input: Question: The sedation and drowsiness that mirtazapine produces are directly related to its interaction with the receptors: 
 Options:  <1> 5-HT1. <2> Adrenergic 1 and 2. <3> Histaminergic H1. <4> GABA <5> Muscarinic cholinergic


Output: 3