Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Does fibroblast growth factor 8 regulate postnatal development of paraventricular nucleus neuroendocrine cells?
Answer: First, Fgf8 hypomorphy did not eliminate VP and CRH neurons in the mouse PVN, but rather disrupted the postnatal timing of neuropeptide expression onset in PVN neurons. Second, Fgf8 hypomorphy may, in part, be an explanation for affective disorders involving hyperactivity of the HPA axis, such as anxiety.

Answer: yes


Question: Question: Does long-term treatment with methotrexate or tumor necrosis factor alpha inhibitors increase epstein-barr virus load in patients with rheumatoid arthritis?
Answer: Long-term usage of methotrexate or TNFalpha inhibitors in patients with RA does not significantly influence EBV load in PBMCs.

Answer: no


Question: Question: Do bile duct crystals contribute to sphincter of Oddi dysfunction?
Answer: Bile duct crystals occur infrequently in patients with symptoms after cholecystectomy and are found in patients with normal and abnormal biliary sphincter manometry. This study suggests that the presence of bile duct crystals, or microlithiasis, does not play a role in sphincter of Oddi dysfunction.

Answer:
no