In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Example Input: Question: Protein kinase A (PKA): 
 Options:  <1> It induces the synthesis of glycogen in response to an increase in glucagon in the blood. <2> It is a membrane protein that is activated in response to an increase in circulating GTP. <3> It is activated through the cAMP produced in response to an increase in adrenaline in the circulation. <4> It inhibits the lipolysis of triacylglycerides accumulated in adipose tissue, in response to an increase in intracellular cAMP. <5> It is a monomeric protein that inhibits the synthesis of ATP and muscle contraction.
Example Output: 3

Example Input: Question: A biosensor consists of: 
 Options:  <1> A receiver, a transducer, and an enzymatic brand. <2> A receptor and an enzymatic brand. <3> A transducer and an enzymatic brand. <4> A receiver and a transducer. <5> A receptor and an antibody.
Example Output: 4

Example Input: Question: In a patient with asthma symptoms, diagnostic confirmation of the disease will be made first by: 
 Options:  <1> The finding of a reversible obstruction of air flow in spirometry. <2> A positive allergic skin test. <3> An increase in the number of eosinophils in the induced sputum. <4> The elevation of nitric oxide in exhaled air (FENO). <5> The presence of a specific IgE in blood to an aeroallergen.
Example Output:
1