TASK DEFINITION: Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
PROBLEM: Context: Telomeres may regulate human disease by at least two independent mechanisms. First, replicative senescence occurs once short telomeres generate DNA-damage signals that produce a barrier to tumor progression. Second, telomere position effects (TPE) could change gene expression at intermediate telomere lengths in cultured human cells. Here we report that telomere length may contribute to the pathogenesis of facioscapulohumeral muscular dystrophy (FSHD). FSHD is a late-onset disease genetically residing only 25-60 kilobases from the end of chromosome 4q. We used a floxable telomerase to generate isogenic clones with different telomere lengths from affected patients and their unaffected siblings. DUX4, the primary candidate for FSHD pathogenesis, is upregulated over ten-fold in FSHD myoblasts and myotubes with short telomeres, and its expression is inversely proportional to telomere length. FSHD may be the first known human disease in which TPE contributes to age-related phenotype. 
 Question: Which disease is associated with the ectopic expression of the protein encoded by the gene DUX4?

SOLUTION: fshd

PROBLEM: Context: On 1 January 2013, Saint-Germain-sur-l'Arbresle and Nuelles merged becoming one commune called Saint-Germain-Nuelles. 
 Question: What was replaced Saint-Germain-sur-l'Arbresle?

SOLUTION: saint-germain-nuelles

PROBLEM: Context: It was a cold winter day. A woman drove up to the Rainbow Bridge tollbooth . "I'm paying for myself, and for the six cars behind me," she said with a smile, handing over seven tickets. One after another, the next six drivers arriving at the tollbooth were informed, "Some lady up ahead already paid your fare." It turned out that the woman, Natalie Smith, had read something on a friend's refrigerator: "Practice random kindness and senseless acts of beauty." The phrase impressed her so much that she copied it down. Judy Foreman spotted the same phrase on a warehouse wall far away from home. When it stayed on her mind for days, she gave up and drove all the way back to copy it down. "I thought it was beautiful," she said, explaining why she'd taken to writing it at the bottom of all her letters, "like a message from above." Her husband, Frank, liked the phrase so much that he put it up on the classroom wall for his students, one of whom was the daughter of Alice Johnson, a local news reporter. Alice put it in the newspaper, admitting that though she liked it, she didn't know where it came from or what it really meant. Two days later, Alice got a call from Anne Herbert, a woman living in Marin. It was in a restaurant that Anne wrote the phrase down on a piece of paper, after turning it around in her mind for days. "Here's the idea," Anne says. "Anything you think there should be more of, do it randomly." Her fantasies include painting the classrooms of shabby schools, leaving hot meals on kitchen tables in the poor part of town, and giving money secretly to a proud old lady. Anne says, " _ ." The acts of random kindness spread. If you were one of those drivers who found your fare paid, who knows what you might have been inspired to do for someone else later. Like all great events, kindness begins slowly, with every single act. Let it be yours! 
 Question: Who came up with the phrase according to the passage?

SOLUTION:
anne herbert.