instruction:
Translate the given Spanish text to English
question:
The present invention provides novel beta-secretase inhibitors of the general formula (I), where the variables A 1 , A 2 , L 1 , L 2 , L 3 , R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 are as defined in the claims, a method for their use in treating Alzheimer's disease, and methods for their use in reducing memapsin 2 catalytic activity.
answer:
La presente invencion proporciona nuevos inhibidores de beta-secretasa de la formula general (I) (ver formula (I)), en donde las variables A1, A2, L1, L2, L3, R1, R2, R3, R4, R5, R6 y R7 son como se definio en las reivindicaciones, un metodo para su uso en el tratamiento de enfermedad de Alzheimer, y metodos para su uso en reducir la actividad catalitica de memapsina 2.


question:
The piston can prevent refilling of a syringe.
answer:
El pistón puede evitar el relleno de una jeringuilla.


question:
The plastic frame is made of an 18% ??
answer:

Bastidor de plastico con material radiopacante al 18% ??