Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Ex Input:
The 80-string koto (or hachijugen) was an invention of Japanese composer Michio Miyagi which appeared In 1923.

Ex Output:
By whom was 80-string koto discovered?


Ex Input:
Missense mutations in ubiquilin 2 (UBQLN2) cause ALS with frontotemporal dementia (ALS-FTD). Animal models of ALS are useful for understanding the mechanisms of pathogenesis and for preclinical investigations. However, previous rodent models carrying UBQLN2 mutations failed to manifest any sign of motor neuron disease. Here, we show that lines of mice expressing either the ALS-FTD-linked P497S or P506T UBQLN2 mutations have cognitive deficits, shortened lifespans, and develop motor neuron disease, mimicking the human disease. Neuropathologic analysis of the mice with end-stage disease revealed the accumulation of ubiquitinated inclusions in the brain and spinal cord, astrocytosis, a reduction in the number of hippocampal neurons, and reduced staining of TAR-DNA binding protein 43 in the nucleus, with concomitant formation of ubiquitin

Ex Output:
Which human disease is associated with mutated UBQLN2


Ex Input:
Associacao Sportiva Sociedade Unida play their home games at Estadio Edgar Borges Montenegro, commonly known as Edgarzao.

Ex Output:

In what home venue does Associação Sportiva Sociedade Unida play?