Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Does δNp63α enhance the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2?
Answer: Here, we report that GLI2 is the novel target gene of ΔNp63α and that ΔNp63α-GLI2 crosstalk in osteosarcoma cells is a necessary event in osteosarcoma progression. Defining the exact mechanisms involved in this interaction that mediate the pathogenesis of osteosarcoma promises to identify targets for drug therapy.

Answer: yes


Question: Question: Do nAT1 genotypes predict response to mesalamine in patients with ulcerative colitis?
Answer: NAT1 genotypes do not predict response or side effects to mesalamine in patients with UC. Variations caused by non-genomic effects may be associated with the clinical response to 5-ASA.

Answer: no


Question: Question: Is elevation of only one rheumatoid factor isotype associated with increased prevalence of rheumatoid arthritis -- a population based study?
Answer: In contrast to a combined elevation of IgM and IgA RF, elevation of only one RF isotype may not be a significant risk factor for the development of RA.

Answer:
no