Write a fact related to the given fact, based on the given topic word. Note that, your fact should have at least one word in common with the given fact. All facts in this task refer to scientific facts. Your related fact must form a chain with the given fact. Chains form when two facts connect together to produce the third fact. An example of a chain is: "pesticides cause pollution" (given fact) + "pollution can harm animals" (related fact) → "pesticides can harm animals" (connected chain). Avoid creating simple paraphrases of the given fact. While your generated fact should be related to the input fact, they must describe slightly different scientific phenomena. It's okay if your related fact includes some irrelevant information, provided that it has some overlap with the given fact and it contains some words corresponding to the provided topic.

Fact: Sperm pass out of the body through the urethra. 
Topic: urethra tube penis.
Urine leaves the bladder in a single tube, the urethra, that runs to the penis or to the vagina.

Fact: Amphibians have permeable skin that easily absorbs substances from the environment. 
Topic: amphibian permeable.
Chemicals can be very toxic to permeable, amphibian skin.

Fact: a graduated cylinder is used to measure volume of a liquid. 
Topic: graduated cylinder.

First, the bottle is calibrated with a graduated cylinder.