Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Ex Input:
Context: Ion Assault is a multidirectional shooter video game developed by Coreplay and published by Black Inc. for the Xbox Live Arcade, PlayStation Network, and Microsoft Windows. 
 Question: Who worked on Ion Assault?

Ex Output:
coreplay


Ex Input:
Context: NADPH oxidase (Nox) family enzymes are one of the main sources of cellular reactive oxygen species (ROS), which have been shown to function as second messenger molecules. To date, seven members of this family have been reported, including Nox1-5 and Duox1 and -2. With the exception of Nox2, the regulation of the Nox enzymes is still poorly understood. Nox1 is highly expressed in the colon, and it requires two cytosolic regulators, NoxO1 and NoxA1, as well as the binding of Rac1 GTPase, for its activity. In this study, we investigate the role of the tyrosine kinase c-Src in the regulation of ROS formation by Nox1. We show that c-Src induces Nox1-mediated ROS generation in the HT29 human colon carcinoma cell line through a Rac-dependent mechanism. Treatment of HT29 cells with the Src inhibitor PP2, expression of a kinase-inactive form of c-Src, and c-Src depletion by small interfering RNA (siRNA) reduce both ROS generation and the levels of active Rac1. This is associated with decreased Src-mediated phosphorylation and activation of the Rac1-guanine nucleotide exchange factor Vav2. Consistent with this, Vav2 siRNA that specifically reduces endogenous Vav2 protein is able to dramatically decrease Nox1-dependent ROS generation and abolish c-Src-induced Nox1 activity. Together, these results establish c-Src as an important regulator of Nox1 activity, and they may provide insight into the mechanisms of tumor formation in colon cancers. 
 Question: Which NADPH oxidase family member requires interaction with NOXO1 for function?

Ex Output:
nadph oxidase 1


Ex Input:
Context: Soviet troops approached the Lithuanian territory on December 12, 1918. About 5,000 of them were Lithuanians. Three divisions were employed: Pskov division , International Division , and 17th Division . The divisions did not have a common military commander. Later more units were sent from Russia. The soviets also recruited partisan groups behind the front lines. Soviet soldiers were poorly supplied and had to support themselves by requisitioning food, horses, and clothes from local residents. Lithuania could not offer serious resistance as at the time its army consisted only of about 3,000 untrained volunteers. Only local partisans, armed with weapons acquired from retreating Germans, offered brief resistance. Red Army captured one town after another: Zarasai and Svencionys , Utena , Rokiskis , Vilnius , Ukmerge and Panevezys , Siauliai , Telsiai . That accounted for about of the Lithuanian territory. The front somewhat stabilized when Soviet forces were stopped near the Venta River by Latvian and German units . Also Germans slowed down withdrawal of their troops after the Spartacist uprising was subdued on January 12. Southern Lithuania was a little better protected as Germans retreated from Ukraine through Hrodna. To prevent fights between retreating Germans and the Red Army, the Soviets and Germans signed a treaty on January 18. The treaty drew a temporary demarcation line that went through Daugai, Stakliskes, and 10 kilometres east of Kaisiadorys-Jonava-Kedainiai railway. That barred Bolshevik forces from directly attacking Kaunas, Lithuania's second-largest city. The Red Army would need to encircle Kaunas and attack through Alytus or Kedainiai. The operation to take Kaunas began on February 7. 
 Question: What happened first, Germans signed a treaty or the operation to take Kaunas began?

Ex Output:

germans signed a treaty