Turn the given fact into a question by a simple rearrangement of words. This typically involves replacing some part of the given fact with a WH word. For example, replacing the subject of the provided fact with the word "what" can form a valid question. Don't be creative! You just need to rearrange the words to turn the fact into a question - easy! Don't just randomly remove a word from the given fact to form a question. Remember that your question must evaluate scientific understanding. Pick a word or a phrase in the given fact to be the correct answer, then make the rest of the question. You can also form a question without any WH words. For example, "A radio converts electricity into?"

[Q]: Fact: a thinning and weakening of bone is a disease in which osteoclasts are more active than osteoblasts.
[A]: a thinning and weakening of bone is a disease in which osteoclasts are more active than what?


[Q]: Fact: Earth's tilt on its spinning axis causes the seasons to change.
[A]: What does Earth's tilt on spinning axis change?


[Q]: Fact: vesicle transport requires energy, and is a form of diffusion.
[A]:
what is vesicle transport a form of?