In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Input: Consider Input: Paragraph: The recent coronavirus pandemic follows in its early stages an almost exponential expansion, with the number of cases as a function of time reasonably well fit by N (t) ∝ e αt , in many countries. We analyze the rate α in different countries, choosing as a starting point in each country the first day with 30 cases and fitting for the following 12 days, capturing thus the early exponential growth in a rather homogeneous way. We look for a link between the rate α and the average temperature T of each country, in the month of the epidemic growth. We analyze a base set of 42 countries, which developed the epidemic earlier, and an extended set of 88 countries, which developed the epidemic more recently. Fitting with a linear behavior α(T ), we find evidence in both datasets for a decreasing growth rate as a function of T , at 99.66%C.L. and 99.86%C.L. in the base and extended dataset, respectively. In the base set, going beyond a linear model, a peak at about (7.7 ± 3.6) • C seems to be present in the data. Our findings give hope that, for northern hemisphere countries, the growth rate should significantly decrease as a result of both warmer weather and lockdown policies. In general the propagation should be hopefully stopped by strong lockdown, testing and tracking policies, before the arrival of the next cold season. I. 
 Title: Temperature dependence of COVID-19 transmission

Output: True


Input: Consider Input: Paragraph: The APETALA2 (AP2) genes represent the AP2 group within a large group of DNA-binding proteins called AP2/EREBP. The AP2 gene is functional and necessary for flower development, stem cell maintenance, and seed development, whereas the other members of AP2 group redundantly affect flowering time. Here we study the phylogeny of AP2 group genes in spermatophytes. Spermatophyte AP2 group genes can be classified into AP2 and TOE types, six clades, and we found that the AP2 group homologs in gymnosperms belong to the AP2 type, whereas TOE types are absent, which indicates the AP2 type gene are more ancient and TOE type was split out of AP2 type and losing the major function. In Brassicaceae, the expansion of AP2 and TOE type lead to the gene number of AP2 group were up to six. Purifying selection appears to have been the primary driving force of spermatophyte AP2 group evolution, although positive selection occurred in the AP2 clade. The transition from exon to intron of AtAP2 in Arabidopsis mutant leads to the loss of gene function and the same situation was found in AtTOE2. Combining this evolutionary analysis and published research, the results suggest that typical AP2 group genes may first appear in gymnosperms and diverged in angiosperms, following expansion of group members and functional differentiation. In angiosperms, AP2 genes (AP2 clade) inherited key functions from ancestors and other genes of AP2 group lost most function but just remained flowering time controlling in gene formation. In this study, the phylogenies of AP2 group genes in spermatophytes was analyzed, which supported the evidence for the research of gene functional evolution of AP2 group. 
 Title: Expansion and Functional Divergence of AP2 Group Genes in Spermatophytes Determined by Molecular Evolution and Arabidopsis Mutant Analysis

Output: True


Input: Consider Input: Paragraph: Pompe disease results from a defect in human acid α-glucosidase (GAA), a lysosomal enzyme 17 that cleaves terminal α1-4 and α1-6 glucose from glycogen. In Pompe disease (also known as 18 Glycogen Storage Disorder type II), the accumulation of undegraded glycogen in lysosomes 19 leads to cellular dysfunction, primarily in muscle and heart tissues. Pompe disease is an active 20 candidate of clinical research, with pharmacological chaperone therapy tested and enzyme 21 replacement therapy approved. Despite production of large amounts of recombinant GAA 22 annually, the structure of GAA has not been reported until now. Here, we describe the first 23 structure of GAA, at 1.7Å resolution. Three structures of GAA complexes reveal the molecular 24 basis for the hundreds of mutations that lead to Pompe disease and for pharmacological 25 chaperoning in the protein. The GAA structure reveals a surprising second sugar-binding site 26 
 Title: The molecular basis for Pompe disease 3 revealed by the structure of human acid α-glucosidase 4 5


Output: True