Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: Trichiasis associated with prostaglandin analog use.
Example Output: adverse drug event

Example Input: There were four females, 20 males, with 19 patients under the age of 18 years and five over the age of 18.
Example Output: non-adverse drug event

Example Input: Ischemic cholangitis caused by transcatheter hepatic arterial chemoembolization 10 months after resection of the extrahepatic bile duct.
Example Output:
non-adverse drug event