Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: For 9 years the patient remained totally asymptomatic.
Example Output: non-adverse drug event

Example Input: A fatal massive pulmonary embolus developed in a patient treated with streptokinase for acute deep vein thrombosis.
Example Output: adverse drug event

Example Input: Glaucoma secondary to epithelial downgrowth and 5-fluorouracil.
Example Output:
adverse drug event