instruction:
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
question:
Ring finger protein 5 pseudogene 1, also known as RNF5P1, is a human gene.
answer:
In what living being can RNF5P1 be found?


question:
In Week 8, the Bears donned their 1940s throwback uniforms against the Carolina Panthers, who had the worst record in the NFC. The Bears scored first on Matt Forte's 13-yard touchdown run, which would be countered by Justin Medlock's 34-yard field goal. The Panthers then took the lead on Louis Murphy's fumble recovery; Panthers quarterback Cam Newton ran with the ball, and lost the ball when Bears safety Major Wright tackled him at the 1-yard line. The ball rolled into the endzone, where Murphy recovered it. Medlock would then kick three more field goals, and by the fourth quarter, the Panthers led 19-7. The tide eventually turned when Panthers punter Brad Nortman shanked a 6-yard punt, and Jay Cutler hit Kellen Davis on a 12-yard touchdown pass with less than seven minutes left in the game. On the first play of the Panthers' next drive, Tim Jennings intercepted Newton and returned the pick 25 yards to regain the lead 20-19, after Cutler's two-point conversion passing attempt was intercepted. Medlock later kicked another field goal to reclaim the lead 22-20 with 2:27 left in the game. Cutler would lead the Bears downfield, and Gould kicked a 41-yard field goal as time expired to give Chicago the victory. The kick was Gould's tenth game-winning field goal, and the first since 2010.
answer:
Who is the Panther's kicker?


question:
The efficacy of RTS,S/AS01 as a vaccine for malaria is being tested in a phase 3 clinical trial. Early results show significant, albeit partial, protection against clinical malaria and severe malaria. To ascertain variations in vaccine efficacy according to covariates such as transmission intensity, choice of adjuvant, age at vaccination, and bednet use, we did an individual-participant pooled analysis of phase 2 clinical data. We analysed data from 11 different sites in Africa, including 4453 participants. We measured heterogeneity in vaccine efficacy by estimating the interactions between covariates and vaccination in pooled multivariable Cox regression and Poisson regression analyses. Endpoints for measurement of vaccine efficacy were infection, clinical malaria, severe malaria, and death. We defined transmission intensity levels according to the estimated local parasite prevalence in children aged 2-10 years (PrP), ranging from 5% to 80%. Choice of adjuvant was either AS01 or AS02. Vaccine efficacy against all episodes of clinical malaria varied by transmission intensity (p=0001). At low transmission (PrP 10%) vaccine efficacy was 60% (95% CI 54 to 67), at moderate transmission (PrP 20%) it was 41% (21 to 57), and at high transmission (PrP 70%) the efficacy was 4% (-10 to 22). Vaccine efficacy also varied by adjuvant choice (p<00001)--eg, at low transmission (PrP 10%), efficacy varied from 60% (95% CI 54 to 67) for AS01 to 47% (14 to 75) for AS02. Variations in efficacy by age at vaccination were of borderline significance (p=0038), and bednet use and sex were not significant covariates. Vaccine efficacy (pooled across adjuvant choice and transmission intensity) varied significantly (p<00001) according to time since vaccination, from 36% efficacy (95% CI 24 to 45) at time of vaccination to 0% (-38 to 38) after 3 years. Vaccine efficacy against clinical disease was of limited duration and was not detectable 3 years after vaccination. Furthermore, efficacy fell with increasing transmission intensity. Outcomes after vaccination cannot be gauged accurately on the basis of one pooled efficacy figure. However, predictions of public-health outcomes of vaccination will need to take account of variations in efficacy by transmission intensity and by time since vaccination. Medical Research Council (UK); Bill & Melinda Gates Foundation Vaccine Modelling Initiative; Wellcome Trust.
answer:

RTS S AS01 vaccine was developed to prevent which disease?