In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[Q]: Question: Before a 49-year-old man, asymptomatic, with a family history of a father who died of prostate cancer, a PSA (Specific Prostate Antigen) of 5.9 ng / ml was identified in a routine company control, with a PSA ratio free / Total PSA of 11% and that in a digital rectal examination there is an increase in consistency in the right prostatic lobe, what is the following clinical indication? 
 Options:  <1> Ask the patient to perform a transrectal ultrasound and prostate biopsy. <2> Perform a abdominopelvic CT scan. <3> Start treatment with 5 alpha reductase inhibitors to halve PSA levels. <4> Start combined treatment of LHRH analogues and antiandrogens. <5> Perform a bone scan.
[A]: 1


[Q]: Question: ADH increases the osmolality of the renal interstitial medium because it increases: 
 Options:  <1> The permeability to urea in the collector tube. <2> The water permeability of the ascending loop of Henle. <3> The flow in the straight vessels. <4> The reabsorption of NaCl in the collecting tubule. <5> The renal excretion of water.
[A]: 1


[Q]: Question: Protein kinase A (PKA): 
 Options:  <1> It induces the synthesis of glycogen in response to an increase in glucagon in the blood. <2> It is a membrane protein that is activated in response to an increase in circulating GTP. <3> It is activated through the cAMP produced in response to an increase in adrenaline in the circulation. <4> It inhibits the lipolysis of triacylglycerides accumulated in adipose tissue, in response to an increase in intracellular cAMP. <5> It is a monomeric protein that inhibits the synthesis of ATP and muscle contraction.
[A]:
3