In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Ex Input:
Paragraph: Primary human airway epithelial cell (hAEC) cultures represent a universal platform to propagate respiratory viruses and characterize their host interactions in authentic target cells. To further elucidate specific interactions between human respiratory viruses and important host factors in the airway epithelium, it is important to make hAEC cultures amenable to genetic modification. However, the short and finite lifespan of primary cells in cell culture creates a bottleneck for the genetic modification of these cultures. In the current study, we show that the incorporation of the Rho-associated protein kinase (ROCK) inhibitor (Y-27632) during cell propagation extends the life span of primary human cells in vitro and thereby facilitates the incorporation of lentivirus-based expression systems. Using fluorescent reporters for fluorescence-activated cell sorting (FACS)-based sorting, we generated homogenously fluorescent hAEC cultures that differentiate normally after lentiviral transduction. As a proof-of-principle, we demonstrate that host gene expression can be modulated post-differentiation via inducible short hairpin (sh)RNA-mediated knockdown. Importantly, functional characterization of these transgenic hAEC cultures with exogenous poly (I:C), as a proxy for virus infection, demonstrates that such modifications do not influence the host innate immune response. Moreover, the propagation kinetics of both human coronavirus 229E (HCoV-229E) and human respiratory syncytial virus (hRSV) were not affected. Combined, these results validate our newly established protocol for the genetic modification of hAEC cultures, thereby unlocking a unique potential for detailed molecular characterization of virus-host interactions in human respiratory epithelium. 
 Title: Establishment of Primary Transgenic Human Airway Epithelial Cell Cultures to Study Respiratory Virus-Host Interactions

Ex Output:
False


Ex Input:
Paragraph: LETTERS that the quantitative assessment of the effectiveness of public health intervention measures for SARS is a difficult task for modelers. To make models useful for assessing the effects of specific intervention measures and for predicting the future dynamics during an ongoing epidemic, we need improved knowledge on the transmission mechanisms, pathogenesis, and the epidemiologic determinants of the spread of the virus. Any retrospective analysis of the 2003 SARS epidemic that improves our knowledge of SARS epidemiology is welcome. 
 Title: SARS epi-demiology and cumulative case curve

Ex Output:
False


Ex Input:
Paragraph: Objective: The objective of this study was to assess epidemiological and clinical features of human bocavirus (HBoV) coinfection with other viruses. Method: Children coinfected with HBoV between January 2012 and December 2014 were enrolled and retrospectively reviewed. Result: A total of 984 patients were stratified into five groups: HBoV infection alone (n ¼ 249), respiratory syncytial virus (RSV) infection alone (n ¼ 649), HBoV coinfection with RSV (n ¼ 28), with human rhinovirus (HRV) (n ¼ 39) and with other virus (n ¼ 19). Length of hospitalization was longer in HBoV coinfection with RSV group than HBoV (9.0 days vs. 7.0 days, p ¼ 0.001), RSV (9.0 days vs. 8.0 days, p ¼ 0.016) infection alone group. Pneumonia was more common in the HBoV coinfection with RSV group compared with the HBoV, RSV infection alone group, respectively (75.0% vs. 44.2%, 31.3%, p < 0.001). HBoV DNA copy numbers (383 000 copies/ml) were positively correlated with the length of hospitalization (r ¼ 0.334, p < 0.001). K E Y W O R D S : coinfection, human bocavirus, respiratory syncytial virus, disease severity, acute respiratory infections Human bocavirus (HBoV) was first identified in 2005 in nasopharyngeal aspirates collected from children with respiratory diseases [1]. Since then, HBoV has been detected worldwide, with prevalence rates between 1. 5% and 19% [2-4]. The recent widespread use of molecular methods has markedly increased the ability to identify respiratory V C The Author(s) [ 
 Title: Impact of RSV Coinfection on Human Bocavirus in Children with Acute Respiratory Infections

Ex Output:

False