Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
Dopamine agonists are increasingly used in the treatment of Parkinson disease, but they may cause serious adverse effects.

Ex Output:
non-adverse drug event


Ex Input:
A 54-year-old man, treated with amiodarone, developed thyrotoxicosis.

Ex Output:
adverse drug event


Ex Input:
A MEDLINE search from 1966 to December 2000 revealed no reports of toxic epidermal necrolysis, erythema multiforme, or Stevens-Johnson syndrome due to ofloxacin therapy.

Ex Output:

non-adverse drug event