In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

Q:  SUMO - 1 modification of PML is known to be required for the formation of PML bodies .

A: SUMO - 1
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Q:  The thiol antioxidant , alpha - lipoate , at clinically relevant doses down - regulated phorbol 12 - myristate 13 - acetate ( PMA ) - induced adhesion molecule expression and cell - cell adhesion .

A: adhesion molecule
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Q:  However , these compounds did not have a significant effect on SDF1 alpha - induced mitogen - activated protein kinase activity .

A:
SDF1 alpha
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