Given a statement and question, generate the answer to the question such that the answer is contained in the statement.

[Q]: statement: A wheeled automobile requires smooth surfaces., question: What does a wheeled automobile require?
[A]: smooth surfaces


[Q]: statement: isolating and transcribing of a gene permits direct detection of gene mutations, question: What permits direct detection of gene mutations?
[A]: isolating and transcribing


[Q]: statement: Running requires a lot of calories., question: What does running require?
[A]:
calories