Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Example Input: A rocket is propelled into space by particles flying out of one end at high speed (see Figure 1.1). A rocket in space moves like a skater holding the fire extinguisher. Fuel is ignited in a chamber, which causes an explosion of gases. The explosion creates pressure that forces the gases out of the rocket. As these gases rush out the end, the rocket moves in the opposite direction, as predicted by Newtons Third Law of Motion. The reaction force of the gases on the rocket pushes the rocket forward. The force pushing the rocket is called thrust. Nothing would get into space without being thrust upward by a rocket. One of the first uses of rockets in space was to launch satellites. A satellite is an object that orbits a larger object. An orbit is a circular or elliptical path around an object. The Moon was Earths first satellite, but now many human- made "artificial satellites" orbit the planet. Thousands of artificial satellites have been put into orbit around Earth (Figure 1.2). We have even put satellites into orbit around the Moon, the Sun, Venus, Mars, Jupiter, and Saturn. There are four main types of satellites. Imaging satellites take pictures of Earths surface for military or scientific purposes. Imaging satellites study the Moon and other planets. Communications satellites receive and send signals for telephone, television, or other types of communica- tions. Navigational satellites are used for navigation systems, such as the Global Positioning System (GPS). The International Space Station, the largest artificial satellite, is designed for humans to live in space while conducting scientific research. Humans have a presence in space at the International Space Station (ISS) (pictured in Figure 1.3). Modern space stations are constructed piece by piece to create a modular system. The primary purpose of the ISS is scientific research, especially in medicine, biology, and physics. Craft designed for human spaceflight, like the Apollo missions, were very successful, but were also very expensive, could not carry much cargo, and could be used only once. To outfit the ISS, NASA needed a space vehicle that was reusable and able to carry large pieces of equipment, such as satellites, space telescopes, or sections of a space station. The resulting spacecraft was a space shuttle, shown in (Figure 1.4). Satellites operate with solar panels for energy. A photograph of the International Space Station was taken from the space shuttle Atlantis in June 2007. Construction of the station was completed in 2011, but new pieces and experiments continue to be added. A space shuttle has three main parts. The part you are probably most familiar with is the orbiter, with wings like an airplane. When a space shuttle launches, the orbiter is attached to a huge fuel tank that contains liquid fuel. On the sides of the fuel tank are two large "booster rockets." All of this is needed to get the orbiter out of Earths atmosphere. Once in space, the orbiter can be used to release equipment (such as a satellite or supplies for the International Space Station), to repair existing equipment such as the Hubble Space Telescope, or to do experiments directly on board the orbiter. When the mission is complete, the orbiter re-enters Earths atmosphere and flies back to Earth more like a glider than an airplane. The Space Shuttle program did 135 missions between 1981 and 2011, when the remaining shuttles were retired. The ISS is now serviced by Russian Soyuz spacecraft. Atlantis on the launch pad in 2006. Since 1981, the space shuttle has been the United States primary vehicle for carrying people and large equipment into space.
Example Output: which of newtons laws of motion explains rocket propulsion?

Example Input: The translocation (9;22) gives rise to the p190(Bcr-Abl) and p210(Bcr-Abl) tyrosine kinase proteins, considered sufficient for leukemic transformation. Philadelphia-positive (Ph(+)) acute leukemia patients failing to respond to initial induction therapy have a poor prognosis with few effective treatment options. Imatinib is an orally administered, potent inhibitor of the Bcr-Abl tyrosine kinase. We conducted a clinical trial in 56 patients with relapsed or refractory Ph(+) acute lymphoblastic leukemia (ALL; 48 patients) or chronic myelogenous leukemia in lymphoid blast crisis (LyBC; 8 patients). Imatinib was given once daily at 400 mg or 600 mg. Imatinib induced complete hematologic responses (CHRs) and complete marrow responses (marrow-CRs) in 29% of ALL patients (CHR, 19%; marrow-CR, 10%), which were sustained for at least 4 weeks in 6% of patients. Median estimated time to progression and overall survival for ALL patients were 2.2 and 4.9 months, respectively. CHRs were reported for 3 (38%) of the patients with LyBC (one sustained CHR). Grade 3 or 4 treatment-related nonhematologic toxicity was reported for 9% of patients; none of the patients discontinued therapy because of nonhematologic adverse reactions. Grade 4 neutropenia and thrombocytopenia occurred in 54% and 27% of patients, respectively. Imatinib therapy resulted in a clinically relevant hematologic response rate in relapsed or refractory Ph(+) acute lymphoid leukemia patients, but development of resistance and subsequent disease progression were rapid. Further studies are warranted to test the effects of imatinib in combination with other agents and to define the mechanisms of resistance to imatinib.
Example Output: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?

Example Input: The film opens with narration over a silhouette of Hill House at night. The narrator, Dr. John Markway (Richard Johnson) tells us, "An evil old house, the kind some people call haunted is like an undiscovered country waiting to be explored. Hill House had stood for 90 years and might stand for 90 more. Silence lay steadily against the wood and stone of Hill House. Whatever walked there walked alone." Title and credits follow, then narration continues, "Scandal, murder, insanity, suicide: The history of Hill House was ideal. It had everything I wanted..." The house was built in New England by a man named Hugh Crain for his wife and young daughter. A horse and carriage accident took the life of the first Mrs. Crain (an uncredited Pamela Buckley) before she even saw the house. Hugh Crain (an uncredited Howard Lang) and young daughter, Abigail (an uncredited Janet Mansell) said a few words over the body, but Hugh was left an embittered man. Crain married again, and the second Mrs. Crain (an uncredited Freda Knorr) also died, falling down the main staircase. Hugh Crain left Abigail with a nurse (an uncredited Susan Richards) and went to England where he died in a drowning accident. Abigail kept the same nursery room her entire life. By the time she was eighty (an uncredited Amy Dalby) she was a bedridden invalid. Her nurse-companion (an uncredited Rosemary Dorken) was a local girl and, it is with this young companion the evil reputation of Hill House really begins. The old lady died while calling for help. The companion was trysting on the verandah with a farm hand. The companion inherited Hill House and occupied it for many years, but eventually hanged herself. The house then passed to a distant relative, named Mrs. Sanderson (Fay Compton).Markway visits Mrs. Sanderson where he convinces her to let him use the house for psychic research. He explains, "I shall occupy the house with a group of carefully selected assistants...I must have specially qualified help to take notes and document any evidence of the supernatural I may find." Eldridge Harper (Ronald Adam), Mrs. Sanderson's lawyer, voices his concern about publicity seekers and the propriety of having women in the house. Harper suggests to Mrs. Sanderson that her nephew, Luke, joins the doctor at Hill House, as he expects to inherit the property. Mrs. Sanderson asks point blank, "Exactly what do you and your assistants expect to find at Hill House?" Markway replies, "Maybe only a few loose floorboards, and maybe, I only say maybe, the key to another world."Dr. Markway, taking a leave of absence from his university professorship, finalizes his list of assistants. Only two end up accepting, Eleanor Lance and Theodora (no last name).Eleanor Lance (Julie Harris) is living with her sister. She is nearly broke and weary after looking after her invalid mother non-stop for eleven years. Mother is now dead, and she fights with her sister over just about everything. She begs to use the car, which is after all, half hers. Her brother-in-law, Bud Fredericks (an uncredited Paul Maxwell) tries to act as mediator between Eleanor and his wife, Carrie (Diane Clare). He is sympathetic to Eleanor's plight, but their daughter, Dora (an uncredited Verina Greenlaw) takes her cues from her mother, and taunts her Aunt Eleanor. On the vacation plan, Bud sides with Eleanor, "I think you should have a vacation, Nell." Carrie objects, but Eleanor is not to be deterred and she shows her family how she reacts when pushed to her breaking point. She is normally quiet and meek, but when pushed is loud and assertive.Nell decides to take the car and confronts the garage attendant (an uncredited Claude Jones) for the keys. She departs Boston along U.S. 50 and Route 238 to Hill House. We hear Nell thinking and she reveals she will never return to live with her sister. In fact, most of what we learn of Eleanor is hearing her thoughts.Eleanor
Example Output:
Who rescues Eleanor?