In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

[Q]: Paragraph: Executive summary Suicide mortality Suicide attempts Health system and societal risk factors Community and relationship risk factors What protects people from the risks of suicide? The current situation in suicide prevention What are countries doing about suicide prevention now? Current legal status of suicide around the world and perspectives for change How can countries create a comprehensive national strategy and why is it useful? How can progress be tracked when evaluating a national suicide prevention strategy? The cost and cost-effectiveness of suicide prevention efforts The way forward for suicide prevention What can be done and who needs to be involved? Forging a way forward What does success look like? Key messages REFERENCES ANNEXES Annex 1. Estimated numbers and rates of suicide by sex and age, 2000 and 2012 Annex 2: WHO Member States grouped by WHO Region and average income per capita 
 Title: WHO Library Cataloguing-in-Publication Data CONCEPTUALIZATION AND GUIDANCE
[A]: True


[Q]: Paragraph: MRNA2 of the arteriviruses lactate dehydrogenase-elevating virus (LDV) and equine arteritis virus (EAV) encodes two proteins that are read in different frames, an about 26 kDa minor envelope glycoprotein and an about 8 kDa protein that lacks N-glycosylation sites and a signal peptide, but possesses a central hydrophobic segment. Recent studies have shown that both proteins of EAV are translated from mRNA 2 in EAV infected BHK cells, that the 8 kDa protein is membrane associated and that small amounts of it are recovered in purified virions (Snijder, E.J., van Tol, H., Pederson, K.W., Raamsman, M.J.B., de Vries, A.A.F., 1999. Identification of a novel structural protein of arteriviruses. J. Virol. 73, 6335-6345). The authors concluded that the 8 kDa protein is another arterivirus envelope protein and designated it E protein. However, we have not detected a significant level of an 8 kDa protein in LDV virions and thus conclude that it is not a structural virion component. 
 Title: An ORF-2a protein is not present at a significant level in virions of the arterivirus lactate dehydrogenase-elevating virus
[A]: True


[Q]: Paragraph: The objective of the present study was to determine if chicken melanoma differentiation-associated gene 5 (MDA5) senses infectious bursal disease virus (IBDV) infection to initiate and amplify an innate immune response in the chicken MDA5 (chMDA5) signaling pathway. Chicken embryo fibroblast DF-1 cells were infected with IBDV LP1 at a multiplicity of infection (MOI) of 0.5 or 10. In addition, knockdown and overexpression of chMDA5 were performed by transfecting DF-1 cells with chMDA5targeting small interfering RNA (siRNA) or chMDA5expressing DNA. The transfected cells were infected with IBDV LP1 at an MOI of 10. Cell culture supernatants and lysates were collected at 2, 8, 16 and 24 hours postinfection (hpi) for IBDV titer determination and RNA extraction, respectively. IBDV RNA loads and mRNA expression levels of chicken MDA5, interferon-b (IFN-b) promoter stimulator 1 (IPS-1), interferon regulatory factor-3 (IRF-3), IFN-b, double-stranded RNA-dependent protein kinase (PKR), 2 0 ,5 0 -oligoadenylate synthetase (OAS), myxovirus resistance gene (Mx), and major histocompatibility complex class I (MHC class I) were determined by real-time RT-PCR. The IBDV titer increased up to 1.4 9 10 7 plaqueforming units (PFU)/mL at 24 hpi, and the IBDV RNA load reached 464 ng/lL at 24 hpi. The mRNA expression levels of chicken MDA5, IRF-3, IFN-b, PKR, OAS, Mx and MHC class I in IBDV-infected DF-1 cells exhibited significant (p \ 0.05) upregulation up to 906-, 199-, 26,310-, 12-, 66,144-, 64,039-and 33-fold, respectively. Expressed chMDA5 from transfection and double-stranded RNA from IBDV infection were localized or colocalized in the cytoplasm of DF-1 cells at 16 hpi. When chMDA5 was knocked down in DF-1 cells, IBDV titers and RNA loads were significantly higher (p \ 0.05) than those in DF-1 cells without chMDA5 knockdown at 24 hpi. The expression levels of chicken MDA5, IRF-3, IFN-b and MHC class I in chMDA5-knockdown DF-1 cells were significantly lower (p \ 0.05) at 16 and 24 hpi. DF-1 cells overexpressing chMDA5 by transfection with chMDA5 expressing DNA had significantly lower (p \ 0.05) IBDV titers and RNA loads at 16 and 24 hpi and showed significantly higher (p \ 0.05) expression of chicken MDA5, IRF-3, IFN-b, PKR, OAS, Mx and MHC class I at 2 hpi. The results indicated that chicken MDA5 recognized IBDV infection and that this interaction resulted in the activation of chMDA5-related innate immune genes and upregulation of chicken MHC class I. 
 Title: Chicken melanoma differentiation-associated gene 5 (MDA5) recognizes infectious bursal disease virus infection and triggers MDA5-related innate immunity
[A]:
False