Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: About three weeks into the therapy regimen, he complained of severe retrosternal chest oppression.

Output: non-adverse drug event


Input: Consider Input: Peculiar nail-changes in a 70-year-old woman with rheumatoid arthritis occurring after approximately 1 year of penicillamine treatment are described.

Output: adverse drug event


Input: Consider Input: Despite treatment in the intensive care unit, the woman died on the sixth day after admission.


Output: non-adverse drug event