Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
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Question: Context: Christianson syndrome (CS) is an X-linked neurodevelopmental and neurological disorder characterized in males by core symptoms that include non-verbal status, intellectual disability, epilepsy, truncal ataxia, postnatal microcephaly and hyperkinesis. CS is caused by mutations in the SLC9A6 gene, which encodes a multipass transmembrane sodium (potassium)-hydrogen exchanger 6 (NHE6) protein, functional in early recycling endosomes. The extent and variability of the CS phenotype in female heterozygotes, who presumably express the wild-type and mutant SLC9A6 alleles mosaically as a result of X-chromosome inactivation (XCI), have not yet been systematically characterized. Slc9a6 knockout mice (Slc9a6 KO) were generated by insertion of the bacterial lacZ/-galactosidase (-Gal) reporter into exon 6 of the X-linked gene. Mutant Slc9a6 KO male mice have been shown to develop late endosomal/lysosomal dysfunction associated with glycolipid accumulation in selected neuronal populations and patterned degeneration of Purkinje cells (PCs). In heterozygous female Slc9a6 KO mice, -Gal serves as a transcriptional/XCI reporter and thus facilitates testing of effects of mosaic expression of the mutant allele on penetrance of the abnormal phenotype. Using -Gal, we demonstrated mosaic expression of the mutant Slc9a6 allele and mosaically distributed lysosomal glycolipid accumulation and PC pathology in the brains of heterozygous Slc9a6 KO female mice. At the behavioral level, we showed that heterozygous female mice suffer from visuospatial memory and motor coordination deficits similar to but less severe than those observed in X-chromosome hemizygous mutant males. Our studies in heterozygous Slc9a6 KO female mice provide important clues for understanding the likely phenotypic range of Christianson syndrome among females heterozygous for SLC9A6 mutations and might improve diagnostic practice and genetic counseling by helping to characterize this presumably underappreciated patient/carrier group. 
 Question: Mutation of which gene is implicated in the Christianson syndrome?

Answer: slc9a6


Question: Context: The 1688 Glorious Revolution replaced James II and VII with his Protestant daughter Mary II and her husband William III and II. Since neither Mary or her sister Anne had surviving children, the 1701 Act of Settlement ensured a Protestant successor by excluding Catholics from the English and Irish thrones, and that of Great Britain after the 1707 Act of Union. When Anne became the last Stuart monarch in 1702, her heir was the distantly related but Protestant Sophia of Hanover, not her Catholic half-brother James Francis Edward. Sophia died two months before Anne in August 1714; her son became George I and the pro-Hanoverian Whigs controlled government for the next 30 years. 
 Question: What happened first, 1701 Act of Settlement or 1707 Act of Union?

Answer: 1701 act of settlement


Question: Context: The MIT Museum is located near the north shore of the Charles River Basin in Cambridge, MA, a few blocks from the central part of the MIT campus. The MIT Museum is accessible via public transportation, and is within three miles of two major interstate highways. The Museum is approximately a 30 minute walk from downtown Boston or from Harvard Square. BY SUBWAY Take the Red Line to either Central Square Station or Kendall Square/MIT Station. From Central Square: Walk down Mass. Ave. toward Boston and the main MIT campus. The Museum is on the left at the corner of Front St. From Kendall/MIT Station at the east end of campus: Walk down Main St., away from Boston, to Windsor St., turn left, take the second right onto Front St., and continue to the museum entrance. BY BUS The Dudley/Harvard Square bus travels along Massachusetts Ave. between Boston and Harvard Square. The MIT Museum is across the street from Novartis and a gas station. From Harvard Square, get off at either Sidney St. or Albany St. From Boston, get off at Front St. BY CAR For directions from your doorstep to MIT, Google offers excellent mapping services including directions from anywhere in the U.S. and Canada. Recorded Directions to the Museum: (415) 561-0399 Besides, you can go the Museum via Commuter Rail. You can easily connect to the MBTA Red Line from South Station, or take the green line to the red line from North Station and get off at Central or Kendall Square. 
 Question: What should you do if you want to get Recorded Directions to the Museum?

Answer:
(415) 561-0399