Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

[Q]: Question: Are immunologic marker paths for seroconversion : single determinations of immunoglobulin A and beta 2-microglobulin adequate to estimate time of HIV infection . Multicohort Analysis Project Workshop . Part II?
Answer: Further study of how serum IgA reflects HIV infection and careful clinical and statistical assessment of reduced beta 2M from 5 or 6 years after HIV infection are needed. The dependence of marker paths on mode of HIV transmission suggests that sexual transmission may have implications for HIV disease progression. The feasibility of using serum IgA and beta 2M, evaluable in single stored blood samples, to estimate time of HIV infection has been set back by our results.
[A]: no


[Q]: Question: Is apoptosis inhibitor-5 overexpression associated with tumor progression and poor prognosis in patients with cervical cancer?
Answer: API5 expression is associated with pERK1/2 in a subset of cervical cancer patients and its expression predicts poor overall survival, supporting that API5 may be a promising novel target for therapeutic interventions.
[A]: yes


[Q]: Question: Does inhibition of mTOR with sirolimus attenuate progression of liver and kidney disease in PCK rats?
Answer: Sirolimus failed to attenuate progression of kidney and liver disease in PCK rats. The lack of a protective effect might be due to intrinsic or acquired rapamycin resistance in this animal model of ARPKD.
[A]:
no