instruction:
Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
question:
Context: Rose Elliot (Irene Miracle), a poet living alone in New York City, discovers an ancient book called The Three Mothers. It tells of the existence of three evil sisters who rule the world with sorrow, tears, and darkness. The book, written by an architect named Varelli, reveals that the three dwell inside separate homes that had been specially designed and built for them by the architect in Rome, Freiburg, and New York. Rose suspects that she is living in one of the buildings and writes to her brother Mark (Leigh McCloskey), a music student in Rome, urging him to visit her. Using clues provided in Varelli's book as a guide, Rose searches the cellar of her building and discovers a hole in the floor which leads to a water-filled ballroom. After accidentally dropping her keys into the water, she enters the flooded room. Swimming under the surface, she sees a portrait bearing the words "Mater Tenebrarum" and is able to reclaim the keys. A putrid corpse suddenly rises from the depths, frightening her. She escapes, although a shadowy figure watches her leave the basement.In Rome, Mark attempts to read Rose's letter during class. He is distracted by the intense gaze of a beautiful student (Ania Pieroni). When the class ends she leaves suddenly; Mark follows, leaving the letter behind. His friend Sara (Eleonora Giorgi) picks up the letter, and eventually reads it. Horrified by the letter's contents, she takes a taxi to a library and locates a copy of The Three Mothers. While looking for an exit, Sara is attacked by a monstrous figure who recognizes the book. She throws the book to the ground and escapes. Later that night, she seeks the company of a neighbor named Carlo (Gabriele Lavia) and both are stabbed to death by a gloved killer. Mark discovers the bodies and two torn fragments from Rose's letter. After the police arrive, he walks out of Sara's apartment and sees a taxi slowly driving by. In it is the music student, staring at him intently once again.Mark telephones Rose but is unable to hear her clearly. He promises to visit just before the connection fails. Cut off, Rose sees two shadowy figures preparing to enter her apartment. She leaves through a back door, but is followed. In a decrepit room, she is grabbed from behind by a clawed assailant and brutally murdered.Upon arriving in New York, Mark meets some of the residents of Rose's building, including a nurse (Veronica Lazar) who is caring for the elderly Professor Arnold (Feodor Chaliapin, Jr.), a wheelchair-bound mute. Mark learns from the sickly Countess Elise (Daria Nicolodi) that Rose has disappeared. Elise explains how Rose had been acting strangely. After the two find blood on the carpet outside Rose's room, Mark follows the stains. He suddenly becomes ill and falls unconscious. Elise sees a black-robed figure dragging Mark away, but the figure suddenly stops and gives chase to Elise. She is attacked by dozens of cats, who bite and claw at her flesh. The hooded figure then stabs her to death. Mark staggers to the house's foyer where the nurse and caretaker (Alida Valli) put him to bed.The next day, Mark asks Kazanian (Sacha Pitoeff), the antique dealer who sold Rose the Three Mothers book, about Rose. However, the man provides no information. That night, Kazanian drowns several cats in a Central Park pond and accidentally falls into the water. Hundreds of rats from a nearby drain crawl all over him, gnawing his flesh. A hot dog vendor hears Kazanian's cries and rushes over. The man kills Kazanian with a knife.Carol, the caretaker, discovers the horribly mutilated corpse of Elise's butler (Leopoldo Mastelloni) in the Countess' apartment. Shocked, she drops a lit candle which starts a fire. Attempting to put out the flames, she becomes entangled in burning draperies and falls from a window to her death.Meanwhile, Mark uses a clue from Rose's letter to discover that beneath each floor is a secret 
 Question: Who is the caretaker?
answer:
carol


question:
Context: The Packers' utter dominance continued with another overwhelming performance over another NFC power, the Eagles. Aaron Rodgers broke Tom Brady's mark of 288 passes at home without being intercepted. The Green Bay quarterback set several other records for passing at home, including an NFL-record 29 straight touchdown passes without an interception. The Packers scored touchdowns on all three parts of the team, offense, defense, and special teams. Julius Peppers returned an interception for a touchdown, his second of the year, and Micah Hyde returned a punt for a touchdown. The Packers got going from the very beginning. They drove 75 yards on their opening drive, but had to settle for a 27-yard field goal by Crosby. After an Eagles' punt, the Packers marched on a 13 play, 88-yard drive culminating in a 4-yard touchdown pass to Davante Adams. On the drive, the Packers converted three 3rd-and-longs and took 6:47 off the clock. The Eagles punted again, but this time Micah Hyde returned the punt 75 yards for a touchdown, giving the Packers a shocking 17-0 lead. The Eagles responded on their next possession with a 33-yard field goal by Cody Parkey early in the second quarter. The Eagles, though, had no answer for the Packers' passing game. Rodgers marched the Packers 80 yards in merely 6 plays to increase the lead to 24-3 on a 27-yard touchdown pass to Jordy Nelson. After a punt, the Packers struck again. 80 yards on another time consuming drive ending with Eddie Lacy driving in a 1-yard touchdown run, but a failed two-point conversion. The Eagles reached the Packers' 15, but settled for another 33-yard field goal as the half expired. Mark Sanchez was stripped early in the 3rd quarter with Nick Perry recovering. The Eagles defense finally made a stand and forced a punt, but the Eagles were forced to punt on their responding drive. The Eagles' defense couldn't hold this time and Crosby kicked a 33-yard field goal increasing the lead to 33-6. The Eagles buried themselves on the next drive as Sanchez threw a 52-yard pick-six to Julius Peppers (with a blocked PAT), making the score 39-6. The Eagles immediately answered, driving 80 yards (with a 4th down conversion) with Sanchez throwing a 10-yard touchdown pass to Jordan Matthews. However, the Packers struck right back with an 80yard scoring drive capped off with Rodgers throwing a screen pass to Lacy who took it 32 yards for a touchdown, pushing the lead to 46-13. However, Eagles mishaps continued as Sanchez threw an interception to Tramon Williams, but Crosby missed a field goal. Then on the following drive after reaching the Packers 40, Sanchez fumbled and Hayward returned the fumble 49 yards for a touchdown, making the score a mind boggling 53-13. The Eagles were able to March 80 yards and score on a 20-yard touchdown reception by Jeremy Maclin on their next drive closing the scoring. The Packers achieved a new franchise mark, as this was the first time ever since the franchise started playing in the NFL that they scored over 50 points in consecutive games (the Packers had scored over 50 points in 6 consecutive games as a "town team" in 1919, their first season of existence.). Green Bay improved to a record of 7-3. 
 Question: Which team scored more points, Packers or Eagles?
answer:
packers


question:
Context: On the basis of remarkable antitumor activity, programmed death receptor-1 (PD-1) inhibitors pembrolizumab and nivolumab were approved for the treatment of advanced melanoma in the second-line setting following progression on either CTLA-4 inhibitor ipilimumab or BRAF/MEK inhibitors (for BRAF mutated melanoma). Given hypothesized risk of triggering exacerbations of autoimmune diseases and/or chronic viral infections, clinical trials (including regulatory studies) evaluating checkpoint blocking antibodies PD-1 and CTLA-4 have excluded patients with autoimmune diseases, chronic hepatitis B/C virus (HBV/HCV), and/or human immunodeficiency virus (HIV) infections. Herein, we describe two patients with advanced melanoma and concomitant HCV/HIV infections treated with PD-1 inhibitor pembrolizumab. Patient 2 with HIV/HCV coinfection progressed after 2 doses of pembrolizumab. Patient 1 who had HCV alone was treated with pembrolizumab with initial partial response. HCV viral load remained stable after 9 cycles of pembrolizumab following which 12-week course of HCV-directed therapy was commenced, resulting in prompt reduction of HCV viral load below detectable levels. Response is ongoing and HCV viral load remains undetectable. In both patients, no significant toxicities were observed when pembrolizumab was initiated. We argue for the further investigation of checkpoint inhibition in cancer patients with underlying chronic viral infections in the context of carefully designed clinical trials. 
 Question: Which is the target protein of the drug nivolumab?
answer:

programmed death receptor-1