In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

[Q]: Background: Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) are two coronaviruses with demonstrated potential to generate significant nosocomial outbreaks. In particular, MERS continues to pose a significant threat in the Middle East since 2012. Currently, no licensed vaccine or drug treatment is available to treat patients infected with either coronavirus. However, there are some MERS vaccines in the preclinical stage of development. We sought to evaluate the potential impact of targeted vaccination strategies for mitigating SARS and MERS outbreaks in healthcare settings using simple mathematical models and detailed historic transmission trees describing the progression of past nosocomial outbreaks of SARS and MERS. Results: Our findings suggest that vaccination strategies targeting patients and healthcare workers, which have been disproportionately affected during past outbreaks, and assuming two vaccination coverage levels at 50 and 75% have the potential to avert nearly 50% or more of MERS or SARS cases. Conclusion: Our modeling results informed by historic outbreak data for SARS and MERS suggest that vaccination strategies targeting patients could be an effective measure to mitigate and prevent outbreaks in the healthcare setting.
[A]: Evaluating the potential impact of targeted vaccination strategies against severe acute respiratory syndrome coronavirus (SARS- CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) outbreaks in the healthcare setting


[Q]: Background: Disaster is a serious public health issue. Health professionals and community residents are main players in disaster responses but their knowledge levels of disaster medicine are not readily available. This study aimed to evaluate knowledge levels and training needs of disaster medicine among potential disaster responders and presented a necessity to popularize disaster medicine education. Methods: A self-reporting questionnaire survey on knowledge level and training needs of disaster medicine was conducted in Shanghai, China, in 2012. A total of randomly selected 547 health professionals, 456 medical students, and 1,526 local residents provided intact information. The total response rate was 93.7%. Results: Overall, 1.3% of these participants have received systematic disaster medicine training. News media (87.1%) was the most common channel to acquire disaster medicine knowledge. Although health professionals were more knowledgeable than community residents, their knowledge structure of disaster medicine was not intact. Medical teachers were more knowledgeable than medical practitioners and health administrators (p = 0.002). Clinicians performed better than public health physicians (p,0.001), whereas public health students performed better than clinical medical students (p,0.001). In community residents, education background significantly affected the knowledge level on disaster medicine (p,0.001). Training needs of disaster medicine were generally high among the surveyed. 'Lecture' and 'practical training' were preferred teaching methods. The selected key and interested contents on disaster medicine training were similar between health professionals and medical students, while the priorities chosen by local residents were quite different from health professionals and medical students (p,0.001). Conclusions: Traditional clinical-oriented medical education might lead to a huge gap between the knowledge level on disaster medicine and the current needs of disaster preparedness. Continuing medical education and public education plans on disaster medicine via media should be practice-oriented, and selectively applied to different populations and take the knowledge levels and training needs into consideration.
[A]: Knowledge Levels and Training Needs of Disaster Medicine among Health Professionals, Medical Students, and Local Residents in Shanghai, China


[Q]: 14 Zika virus is a single-stranded, positive-sense RNA virus of the family Flaviviridae, which has 15 recently undergone a rapid expansion among humans in the Western Hemisphere. Here, we report 16 a high-resolution map of ribosomal occupancy of the Zika virus genome during infection of 17 mammalian and insect cells, obtained by ribosome profiling. In contrast to some other flaviviruses 18 such as West Nile, we find no evidence for substantial frameshift-induced ribosomal drop-off 19 during translation of the viral polyprotein, indicating that Zika virus must use alternative 20 mechanisms to downregulate levels of catalytically active viral polymerase. We also show that 21 high levels of ribosome-protected fragments map in-frame to two previously overlooked upstream 22 open reading frames (uORFs) initiating at CUG and UUG codons, with likely consequences for 23 the efficiency of polyprotein expression. Curiously, in African isolates of Zika virus, the two 24 uORFs are fused in-frame into a single uORF. A parallel RNA-Seq analysis reveals the 5' end 25 . CC-BY 4.0 International license is made available under a
[A]:
The translational landscape of Zika virus during infection of mammalian and 1 insect cells 2 3