This task is about creating an unanswerable question based on a given passage. Construct a question that looks relevant to the given context but is unanswerable. Following are a few suggestions about how to create unanswerable questions:
(i) create questions which require satisfying a constraint that is not mentioned in the passage
(ii) create questions which require information beyond what is provided in the passage in order to answer
(iii) replace an existing entity, number, date mentioned in the passage with other entity, number, date and use it in the question
(iv) create a question which is answerable from the passage and then replace one or two words by their antonyms or insert/remove negation words to make it unanswerable.

Passage: Because it is normal to have bacterial colonization, it is difficult to know which chronic wounds are infected. Despite the huge number of wounds seen in clinical practice, there are limited quality data for evaluated symptoms and signs. A review of chronic wounds in the Journal of the American Medical Association's "Rational Clinical Examination Series" quantified the importance of increased pain as an indicator of infection. The review showed that the most useful finding is an increase in the level of pain [likelihood ratio (LR) range, 11-20] makes infection much more likely, but the absence of pain (negative likelihood ratio range, 0.64-0.88) does not rule out infection (summary LR 0.64-0.88).
Why is it easy to know which chronic wounds are infected?

Passage: The school has many nationally and internationally acclaimed scholars in social security, health care, health disparities, communication, social and health policy, and individual and family development. Many of the faculty have training in both social work and public health. The school's current dean is Edward F. Lawlor. In addition to affiliation with the university-wide Institute of Public Health, Brown houses 12 research centers. The Brown School Library collects materials on many topics, with specific emphasis on: children, youth, and families; gerontology; health; mental health; social and economic development; family therapy; and management. The library maintains subscriptions to over 450 academic journals.
How many academic journal subscriptions does the Brown School Library have for mental health issues?

Passage: The original town of San Diego was located at the foot of Presidio Hill, in the area which is now Old Town San Diego State Historic Park. The location was not ideal, being several miles away from navigable water. In 1850, William Heath Davis promoted a new development by the Bay shore called "New San Diego", several miles south of the original settlement; however, for several decades the new development consisted only a few houses, a pier and an Army depot. In the late 1860s, Alonzo Horton promoted a move to the bayside area, which he called "New Town" and which became Downtown San Diego. Horton promoted the area heavily, and people and businesses began to relocate to New Town because of its location on San Diego Bay convenient to shipping. New Town soon eclipsed the original settlement, known to this day as Old Town, and became the economic and governmental heart of the city. Still, San Diego remained a relative backwater town until the arrival of a railroad connection in 1878.

What was the main flaw of San Francisco's original location?