Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Example Input: Context: In order to determine the prevalence of latent infection due to Mycobacterium tuberculosis in drug users and to provide centres for drug users with a practical tool for tuberculosis screening, 237 drug users were subjected to the Monotest and, for reference purposes, to the Mantoux test. The overall prevalence of subjects with a tuberculin skin reaction size > or = 5 mm in the Mantoux test was 25.7%; utilizing a cut-off of > or = 10 mm, the prevalence was 11.4%. Irrespective of cut-off, the Monotest showed a sensitivity of > 90% and a specificity of > 80%. At a prevalence of 25.7%, and with cut-offs of > or = 5 or > or = 10 mm, the positive predictive value was 83% or 62.2%, respectively. Irrespective of cut-off, the negative predictive value was > 97%. In conclusion, the Monotest proved satisfactory as a tool for epidemiological screening in a population with a high prevalence for latent tuberculosis, namely drug users. 
 Question: The Mantoux test detects what latent infection/disease?
Example Output: tuberculosis

Example Input: Context: Chronic myeloid leukemia (CML) is characterized by the presence of the Philadelphia chromosome, which is associated with a balanced translocation involving chromosomes 9 and 22 to produce a fusion gene (bcr-abl) that gives rise to a constitutively activated Abl tyrosine kinase. This kinase led to the discovery of several small-molecule inhibitors, imatinib being the first and most successful of these. Resistance to imatinib results in some patients from Abl kinase point mutations. Overcoming imatinib resistance represents one of the biggest challenges facing clinicians in the modern management of CML. In this review, we discuss the current understanding of CML pathophysiology and mechanisms of imatinib resistance and how advancing this knowledge has led to the design of novel therapies in the area of blastic phase CML and Philadelphia chromosome-positive acute lymphoblastic leukemia with previous imatinib failure. 
 Question: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?
Example Output: bcr-abl

Example Input: Context: Hans Christian Andersen put Denmark on the map of the world literature with his stories The Emperor's New Clothes,The Little MermaidandThe Ugly Duckling. Now Copenhagen, the country's capital, has become the center of the world political map, with 190 world leaders attending the climate talks there, not to mention thousands of reporters. Just how much do you know about the Scandinavian country? Denmark is famous for its design culture. At the heart of "Danish Design" is the idea that, as poet and designer Piet Hein puts it: "There is one art, not more, nor less, [and that is] to do all things with artlessness ." Danish design places equal emphasis on practicality and quality. From Lego toys to furniture, Danish products are known for their clean lines, simplicity and functionality. "Remove material where it's not needed. Keep things simple and functional and make them carefully," explained Hans J. Wegner, the first Danish designer to achieve worldwide fame: "The aim is not to create a work of art, but to produce a good chair." "The Danes have done a better job than most in promoting arts in Europe, considering their country's size and population, in the fields of architecture, sculpture and design," writes Helena Smith, reporter with British newspaper the Guardian. The simplicity of Danish design may extend to the quality of life there. Some even claim that the Danes have the highest quality of life of any nation in the world. Kate Vial, a 55-year-old American who has lived and worked in Denmark for more than 30 years, explaining why she chooses to live in Denmark rather than the US, told Germany's biggest news weekly Der Spiegel: "I just chose a simpler lifestyle, one where I could ride my bike all over and where I don't have to make a great living to survive." 
 Question: What is Denmark famous for according to the passage?
Example Output:
design culture