Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

[EX Q]: Computed Tomography was used to demonstrate the increased retro-orbital fat.
[EX A]: non-adverse drug event

[EX Q]: For 9 years the patient remained totally asymptomatic.
[EX A]: non-adverse drug event

[EX Q]: To our knowledge, this is the first report of insulin-induced lipohypertrophy with detailed histological examinations.
[EX A]:
adverse drug event