Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Example Input: Context: In eukaryotic cells, there are two sub-pathways of nucleotide excision repair (NER), the global genome (gg) NER and the transcription-coupled repair (TCR). TCR can preferentially remove the bulky DNA lesions located at the transcribed strand of a transcriptional active gene more rapidly than those at the untranscribed strand or overall genomic DNA. This strand-specific repair in a suitable restriction fragment is usually determined by alkaline gel electrophoresis followed by Southern blotting transfer and hybridization with an indirect end-labeled single-stranded probe. Here we describe a new method of TCR assay based on strand-specific-PCR (SS-PCR). Using this method, we have investigated the role of DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a member of the phosphatidylinositol 3-kinase-related protein kinases (PIKK) family, in the TCR pathway of UV-induced DNA damage. Although depletion of DNA-PKcs sensitized HeLa cells to UV radiation, it did not affect the ggNER efficiency of UV-induced cyclobutane pyrimidine dimers (CPD) damage. We postulated that DNA-PKcs may involve in the TCR process. To test this hypothesis, we have firstly developed a novel method of TCR assay based on the strand-specific PCR technology with a set of smart primers, which allows the strand-specific amplification of a restricted gene fragment of UV radiation-damaged genomic DNA in mammalian cells. Using this new method, we confirmed that siRNA-mediated downregulation of Cockayne syndrome B resulted in a deficiency of TCR of the UV-damaged dihydrofolate reductase (DHFR) gene. In addition, DMSO-induced silencing of the c-myc gene led to a decreased TCR efficiency of UV radiation-damaged c-myc gene in HL60 cells. On the basis of the above methodology verification, we found that the depletion of DNA-PKcs mediated by siRNA significantly decreased the TCR capacity of repairing the UV-induced CPDs damage in DHFR gene in HeLa cells, indicating that DNA-PKcs may also be involved in the TCR pathway of DNA damage repair. By means of immunoprecipitation and MALDI-TOF-Mass spectrometric analysis, we have revealed the interaction of DNA-PKcs and cyclin T2, which is a subunit of the human transcription elongation factor (P-TEFb). While the P-TEFb complex can phosphorylate the serine 2 of the carboxyl-terminal domain (CTD) of RNA polymerase II and promote transcription elongation. A new method of TCR assay was developed based the strand-specific-PCR (SS-PCR). Our data suggest that DNA-PKcs plays a role in the TCR pathway of UV-damaged DNA. One possible mechanistic hypothesis is that DNA-PKcs may function through associating with CyclinT2/CDK9 (P-TEFb) to modulate the activity of RNA Pol II, which has already been identified as a key molecule recognizing and initializing TCR. 
 Question: Which gene strand is targeted by transcription-coupled repair (TCR)?
Example Output: the transcribed strand

Example Input: Context: Mosqueiro is an island near the south bank of the Para River in the Brazilian state of Para, roughly north of downtown Belem. 
 Question: What body of water was Mosqueiro next to?
Example Output: pará river

Example Input: Context: An earthquake is sudden ground movement caused by the sudden release of energy stored in rocks. Earthquakes happen when so much stress builds up in the rocks that the rocks rupture. The energy is transmitted by seismic waves. Earthquakes can be so small they go completely unnoticed, or so large that it can take years for a region to recover. The description of how earthquakes occur is called elastic rebound theory (Figure 1.1). Elastic rebound theory. Stresses build on both sides of a fault, causing the rocks to deform plastically (Time 2). When the stresses become too great, the rocks break and end up in a different location (Time 3). This releases the built up energy and creates an earthquake. Click image to the left or use the URL below. URL: In an earthquake, the initial point where the rocks rupture in the crust is called the focus. The epicenter is the point on the land surface that is directly above the focus (Figure 1.2). In the vertical cross section of crust, there are two features labeled - the focus and the epicenter, which is directly above the focus. Click image to the left or use the URL below. URL: 
 Question: when an earthquake happens, we say that its __________ was located 100 miles northwest of san francisco.
Example Output:
epicenter