instruction:
Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
question:
Context: As elderly people go about their day in Manhattan, Harry walks along a sidewalk with his tabby cat Tonto on a leash, quoting Shakespeare's "King Lear" as he goes. Harry stops in at a grocer, buys some good food for his cat, and jokes that his sexual days are over.Next Harry meets his old friend Jacob on a bench, and tells him that his apartment building is being torn down to build a parking lot. Jacob complains about capitalists, and reassures Harry that he could always move in with him.On the way home, a kid tries to steal Harry's groceries and knocks him down. Harry is helped up by Leroy, his building super.Harry gets into his apartment and talks to Tonto, lamenting that he's been mugged four times in the past year, and that the whole city is getting run down.Some time later, police show up to forcibly remove Harry and his furniture from the building. Harry continues to spout "King Lear" while his son Burt arrives to pick him up.Harry goes to live with Burt and his wife and two grown sons in the suburbs. His younger grandson, Norman, has taken a vow of silence, leading to obvious tension with his brother and parents. Harry later asks Norman for the books that explain his beliefs.Harry goes back to his familiar bench to talk with Jacob, and they both agree it's been a long time since either has been with a woman. Jacob reminisces about his first sexual encounter with a servant girl when he was 14.Harry invites Leroy to dinner at Burt's house, and he plays the piano while Leroy dances to the tune. Leroy later comments that he lives with his 90-year-old mother and can't find a new job, which leads Burt's wife to question why Harry is not getting help from his two other kids.Knowing that he is a burden to Burt, Harry goes to look for his own apartment, but finds that the place he wants will not take cats. He then tells Burt he is going to Chicago to visit Shirley, Burt's sister, but before he leaves he stops at a city morgue to identify the body of Jacob, who has died with no relatives. Harry cries after recalling Jacob's story of losing his virginity.Burt takes Harry to the airport, but Harry soon learns that he can't go through security with Tonto, so he takes a cab to get a bus. Along the route, Harry asks the bus driver to stop so that Tonto can relieve himself, whereupon the cat runs away across a cemetery. The bus driver leaves Harry behind with his luggage, and when Tonto returns, Harry scolds him.Harry walks to a used car lot and buys an old Chevy for $250. He then checks into a motel and calls Burt to tell him what has happened, realizing in the process that his driver's license expired in 1958.Harry drives west rather slowly, with Tonto on the dashboard, recalling how he wanted to drive across the country when he was younger, but his wife and kids came along. He remembers they had many good times though. He confesses to Tonto that he has a great fear of pain, and that when he dies he would like to go quickly rather than the slow way his wife Annie died.Harry picks up two young hitchhikers, one of whom soon gets another ride, while the other a girl named Ginger continues west with Harry. She claims she is 16, and is running away from home to a commune in Boulder.Harry and Ginger get a motel for the night, and after she comes out of the bathroom half-naked, Harry is prompted to recall the first girl he loved, Jessie, whom he has not seen in 50 years. Ginger suggests that they go to see her, even though it's out of their way, and they eventually find her in a nursing home.At first Harry thinks Jessie remembers him, but her thoughts are marked by senility; she calls him Alex yet remembers his wife Annie. Then she suddenly asks Harry to dance, which they do while Ginger looks on.Harry 
 Question: Who is Harry's travelling companion?
answer:
tonto


question:
Context: To determine the efficacy and safety of different doses of secukinumab, a fully human monoclonal antibody for targeted interleukin-17A blockade, in patients with noninfectious uveitis. Three multicenter, randomized, double-masked, placebo-controlled, dose-ranging phase III studies: SHIELD, INSURE, and ENDURE. A total of 118 patients with Behcet's uveitis (SHIELD study); 31 patients with active, noninfectious, non-Behcet's uveitis (INSURE study); and 125 patients with quiescent, noninfectious, non-Behcet's uveitis (ENDURE study) were enrolled. After an initial subcutaneous (s.c.) loading phase in each treatment arm, patients received s.c. maintenance therapy with secukinumab 300 mg every 2 weeks (q2w), secukinumab 300 mg monthly (q4w), or placebo in the SHIELD study; secukinumab 300 mg q2w, secukinumab 300 mg q4w, secukinumab 150 mg q4w, or placebo in the INSURE study; or secukinumab 300 mg q2w, secukinumab 300 mg q4w, secukinumab 150 mg q4w, or placebo in the ENDURE study. Reduction of uveitis recurrence or vitreous haze score during withdrawal of concomitant immunosuppressive medication (ISM). Other end points included best-corrected visual acuity, ISM use (expressed as a standardized ISM score), and safety outcomes. After completion or early termination of each trial, there were no statistically significant differences in uveitis recurrence between the secukinumab treatment groups and placebo groups in any study. Secukinumab was associated with a significant reduction in mean total post-baseline ISM score (P = 0.019; 300 mg q4w vs. placebo) in the SHIELD study. Likewise, secukinumab was associated with a greater median reduction in ISM score versus placebo in the INSURE study, although no statistical analysis of the difference was conducted because of the small sample size. Overall, there was no loss in visual acuity reported in any treatment group during follow-up in all 3 studies. According to descriptive safety statistics, the frequencies of ocular and nonocular adverse events seemed to be slightly higher among secukinumab groups versus placebo across the 3 studies. The primary efficacy end points of the 3 studies were not met. The secondary efficacy data from these studies suggest a beneficial effect of secukinumab in reducing the use of concomitant ISM. 
 Question: Which molecule is targeted by a monoclonal antibody Secukinumab?
answer:
interleukin-17a


question:
Context: Think about how the color of a piece of metal changes with temperature. A coil of an electric stove will start out black, but with added heat will start to glow a dull red. With more heat, the coil turns a brighter red, then orange. At extremely high temperatures the coil will turn yellow-white, or even blue-white (its hard to imagine a stove coil getting that hot). A stars color is also determined by the temperature of the stars surface. Relatively cool stars are red, warmer stars are orange or yellow, and extremely hot stars are blue or blue-white (Figure 1.1). Color is the most common way to classify stars. Table 1.1 shows the classification system. The class of a star is given by a letter. Each letter corresponds to a color, and also to a range of temperatures. Note that these letters dont match the color names; they are left over from an older system that is no longer used. Class O B A F G K M Color Blue Blue-white White Yellowish-white Yellow Orange Red Temperature Range 30,000 K or more 10,000-30,000 K 7,500-10,000 K 6,000-7,500 K 5,500-6,000 K 3,500-5,000 K 2,000-3,500 K Sample Star Zeta Ophiuchi Rigel Altair Procyon A Sun Epsilon Indi Betelgeuse, Proxima Cen- tauri For most stars, surface temperature is also related to size. Bigger stars produce more energy, so their surfaces are hotter. Click image to the left or use the URL below. URL: Click image to the left or use the URL below. URL: 
 Question: extremely high temperature stars are __________.
answer:

blue