Given scientific fact as input, generate the question from this fact such that it can be answered from the input.

Example Input: Fungi is the major cause of disease in agricultural crops.
Example Output: What is the major cause of disease in agricultural crops?

Example Input: Elements are pure substances that make up all matter.
Example Output: Elements are pure substances that make up what?

Example Input: The nucleus is surrounded by a membrane and holds the genetic information for the cell.
Example Output:
What part of the cell is surrounded by a membrane and holds the genetic information for the cell?