In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[EX Q]: Question: The main indication for using 4 drugs in the initial treatment of tuberculosis is: 
 Options:  <1> Affectation of the central nervous system. <2> High prevalence of primary resistance to isoniazid. <3> Cavitated and extensive pulmonary tuberculosis with large bacillary load. <4> Disseminated tuberculosis associated with HIV infection. <5> Extrapulmonary tuberculosis in immunodepressed patients of any origin.
[EX A]: 2

[EX Q]: Question: In relation to the physiology of the complement system, one of the following statements is false: 
 Options:  <1> Most of its components are inactive. <2> Its mode of activation is similar to the coagulation cascade. <3> It is subject to strict control of regulatory mechanisms. <4> It is only activated by two different routes: the classical and the alternative. <5> During its activation, multimolecular complexes are formed.
[EX A]: 4

[EX Q]: Question: Indicate which of the following alterations of the metabolism can occur with gout: 
 Options:  <1> Metabolism of porphyrins. <2> Metabolism of acid amino acids. <3> Metabolism of basic amino acids. <4> Metabolism of glycogen. <5> Metabolism of purines.
[EX A]:
5