Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
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Question: Considerable improvement of myasthenic symptoms was seen in all patients within 3-6 months after the initiation of this therapy.

Answer: non-adverse drug event


Question: Two days prior to admission, metoclopramide 10 mg orally three times per day was started for a gastrointestinal condition.

Answer: non-adverse drug event


Question: Semiquantitative measurements of cytokine mRNA in his bronchoalveolar lavage cells prior to therapy with IFN-alpha revealed high levels of IL-4 and IL-10 mRNA, which decreased significantly with treatment.

Answer:
non-adverse drug event