Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

[EX Q]: Adenomyosis confined to the broad ligament is extremely rare.
[EX A]: non-adverse drug event

[EX Q]: Antibiotic-associated colitis (pseudomembranous colitis) developed in four patients with spinal cord injury and taking oral trimethoprim-sulfamethoxazole.
[EX A]: adverse drug event

[EX Q]: A reduction of up to 33 percent in pituitary tumor size has been reported in more than half of the 27 cases studied from four groups.
[EX A]:
non-adverse drug event