In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Q: Question: In general, water intake should be increased in patients undergoing chemotherapy with the aim of: 
 Options:  <1> Prevent kidney damage. <2> Fluidify bronchial secretions. <3> Relieve post-chemotherapy nausea. <4> Increase the volume. <5> Decrease the risk of infection.

A: 1
****
Q: Question: The simultaneous expression of IgM and IgD is observed for the first time in lymphocytes: 
 Options:  <1> Early Pro-B. <2> B mature. <3> Late Pro-B. <4> Pre-B. <5> B immature

A: 2
****
Q: Question: Which of the following agents has a vasoconstrictor effect? 
 Options:  <1> Endothelin <2> Nitric oxide. <3> Nitrogen. <4> Blastoestimulin. <5> Glycine

A:
1
****