In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Ex Input:
Paragraph: Autoimmune retinopathy (AIR) is a rare immune-mediated retinopathy associated with circulating antiretinal antibodies (ARAs). Other prominent features of AIR include visual field deficits and photoreceptor dysfunction in the setting of progressive unexplained vision loss. The role of inflammation is poorly understood in AIR. Since cytokines play a central role in the initiation and development of inflammation, we evaluated the presence of proinflammatory cytokines and chemokines in AIR patient sera. We demonstrate that IL-6 and CXCL9 are both elevated in AIR patient sera. Moreover, the presence and concentration of these 2 molecules appear to correlate with AIR patient disease severity. This cytokine profile, IL-6 and CXCL9, has been described to participate in a variety of autoimmune and inflammatory diseases. Our study provides support for an activated inflammatory process in AIR and identifies possible mechanisms that can drive autoimmunity in this disease. 
 Title: Elevated serum levels of IL-6 and CXCL9 in autoimmune retinopathy (AIR) patients

Ex Output:
True


Ex Input:
Paragraph: During the replication cycle of Sindbis virus minus-strand synthesis stops normally at the time that plus-strand synthesis reaches a maximum rate. We have isolated and characterized revertants of ts24, a member of the A complementation group of Sindbis HR mutants, that we had demonstrated previously to have a temperature-sensitive defect in the regulation of minus-strand synthesis. These revertants of t&4 replicated efficiently at 40' but nevertheless retained the temperature sensitive defect in the regulation of minus-strand synthesis: they continued to synthesize minus strands late in the replication cycle at 40" but not at 30" and in the presence or absence of protein synthesis. Although failure to regulate the synthesis of minus strands resulted in continuous minus-strand synthesis and in the accumulation of minus strands, the rate of plus-strand synthesis was not increased concertedly. Minus strands synthesized after the rate of plus-strand synthesis had become constant were demonstrated to be utilized as templates for 26 S mRNA synthesis. Thus, the change from an increasing to a constant rate of plus-strand synthesis during the alphavirus replication cycle cannot be governed solely by the number of minus strands that accumulate in infected cells. We present a model for the preferential utilization of minus strands as a mechanism for the cessation of minus-strand synthesis that occurs normally during alphavirus replication. 
 Title: The Effect of Loss of Regulation of Minus-Strand RNA Synthesis on Sindbis Virus Replication

Ex Output:
True


Ex Input:
Paragraph: Supplementary Figure 1. Phylogenetic tree for complete genomes of 91 representative IOL CHIKV strains constructed using the maximum likelihood method. Bootstrap values and sl1-4-specific substitutions are indicated. The SL07 strain used as a genetic background for all in vivo experiments is highlighted with an asterisk. The purple arrow highlights strain LK(EH)CH18608 with the E2-K233E substitution. The blue diamond highlights the Thailand-2009_CK11/53 strain of sl1 used in competition experiment (see Supplementary Fig. 2) . The bar indicates 0.2% nucleotide sequence divergence. (a) Schematic representation of the experimental design. Table shows genetic differences between the competing viruses. A 1:1 ratio (based on pfu) of wt (SL07-226V_Apa) and mut (contains one of the sl2-specific mutations) viruses was presented to Thai colony A. 
 Title: Supplementary information

Ex Output:

False