In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Example Input: Question: Point out the correct answer in relation to the monitoring of plasma drug concentrations: 
 Options:  <1> Allergy reactions are related to the dose administered. <2> The extraction of the blood sample must be done once the balance of drug distribution in the organism has been reached. <3> The information provided by the analytical determination of plasma concentration is sufficient to perform the dosage individualization. <4> Only the immunoassay methods are valid for carrying out the analytical determination of the blood samples. <5> It must be done for all drugs that are administered intravenously.
Example Output: 2

Example Input: Question: What name does the technique used in the treatment of Generalized Anxiety Disorder (GAD) in which the person is asked to assume that their worst fear is met, and then look for realistic solutions to it ?: 
 Options:  <1> Script of the worst scenario. <2> Decatastrofization. <3> Coping with uncertainty. <4> Revaluation of the threat. <5> Processing of meta-concern.
Example Output: 2

Example Input: Question: The mission of the spliceosome is: 
 Options:  <1> Ensure that the transfer RNAs adopt the trefoil configuration. <2> Prevent ribosomes from entering the nucleus. <3> Perform polyadenylation of messenger RNA (mRNA). <4> Degrade defective proteins. <5> Facilitate the maturation of the mRNA precursor, since it approximates the splice points.
Example Output:
5