In this task, you will be shown a passage. You need to write a fill-in-the-gap question based on your understanding of the events that might be inferred from the passage. Your question should be answerable based on the passage and only have one correct answer. Show the gap in your question with a _ .

(CNN) The proportion of Zika-related birth defects during 2016 was nearly 20 times higher than the number seen during the pre-Zika years, according to a new report from the United States Centers for Disease Control and Prevention. In particular, brain abnormalities or microcephaly, where a baby's head size is smaller than expected, occurred about 33 times as often in pregnancies with Zika infections than in the pre-Zika years. Zika, a virus transmitted primarily by mosquitoes and unprotected sex, has been spreading around the globe with locally transmitted cases in the US were first reported in Florida and Texas during 2016. Currently, there is no vaccine to prevent infection.Brain abnormalities or microcephaly occurred about 33 times as often in pregnancies with Zika infectionsNew report is based on data from surveillance programs in three US states
"Other data has shown us the highest risk is the first trimester and early in the second trimester but we don't think there's any safe time in pregnancy to be exposed to _ virus infection," said Honein.

These are the laughing Islamic State fighters who forced desperate Syrian refugees to abandon an escape to Turkey by marching them back across the border at gunpoint. Thousands of people have attempted to flee the across the border to escape ISIS at Tal Abyad after hearing Kurdish militia were advancing towards the town, where they fear there could be a bloodbath. However, their escape route was blocked by heavily armed members of the terror group, who rounded up those trying to flee and marched them back into Syria. The jihadists could then be seen revelling as the Syrians were then made to turn back with their suitcases and belongings into to the ISIS-held territory.Armed ISIS terrorists forced thousands of desperate Syrian refugees to abandon an escape to freedom at gunpointThe men, women and children carried everything they could as they shuffled up to the Tal Abyad border crossingBut many were forced to return after laughing fighters rounded up the refugees and marched them back into Syria
It also said the road linking _ with Raqqa was under YPG control.

Palm Beach, Florida (CNN) Two days after footage of a grisly chemical weapons attack on civilians made its way around the world, President Donald Trump decided to launch a military strike against the Syrian regime responsible for the horrific attack. But while the decision to strike Syrian government targets marked a sharp reversal in the President's stance on Syria -- one that called for a laser-like focus on ISIS and largely ignoring Assad -- the sharp, 180-degree turn didn't happen over a matter of days. 'Holocaust' Months earlier, during an off-the-record holiday gathering with reporters at his opulent Mar-a-Lago estate a week before Christmas, Trump spoke at length about the carnage of the Syrian civil war, revealing that the issue was weighing on him as he prepared to take office. Trump spokeswoman Hope Hicks authorized CNN on Friday to report the contents of his remarks on the topic at the gathering, which CNN attended.Trump ordered a strike against Syria ThursdayTrump said that the chemical weapons attack "crossed a lot of lines for me"

He described the slaughter of civilians in _ as a "holocaust," and remarked on the "high pain threshold" of the population there.