Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
We also discuss the apparent increased thrombotic risk in patients receiving a VAD for chemotherapy induced cardiomyopathy and the implications this may have for the choice of VAD.

Ex Output:
non-adverse drug event


Ex Input:
A challenge with clozapine was feasible and showed no clinical symptoms of eosinophilia.

Ex Output:
non-adverse drug event


Ex Input:
A 600-mg loading dose appears to shorten the time to achieve an adequate antiplatelet effect to about two hours.

Ex Output:

non-adverse drug event