Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Ex Input:
Paragraph: "The cost of the drug wasn’t mentioned – a big oversight. Other news stories pegged it at about $35,000 a year. Adequate job. The story explained: ""But experts stress that Benlysta is not a miracle drug: It only worked in 35 percent of North American patients tested and was not effective for patients with the deadliest form of the disease. Additionally, it did not show positive results in African Americans, who are disproportionately affected by lupus."" There was no discussion of harms. An NPR story, by comparison, pointed out that ""There are side effects, of course, and some of them are pretty serious. In clinical tests involving about 2,100 people, 11 taking Benlysta died compared with 4 getting placebo. About 6 percent of people taking Benlysta got serious infections compared with 5.2 percent on placebo."" The story offered an interesting historical perspective on the evidence: ""The company originally tested Benlysta, known generically as belimumab, as a treatment for rheumatoid arthritis. When a mid-stage trial in lupus patients failed to meet researchers’ goals in 2006, many analysts wrote the drug off and downgraded the company’s stock. But when scientists reanalyzed the data they found that the drug helped block the antibodies that cause lupus symptoms in a subset of patients."" No disease mongering of lupus. Two independent sources were quoted. Not applicable. With no other new drug approved for lupus in 56 years, there’s not been much to compare it with. The story did state that some experts thought this ""could prompt development of other drugs that are even more effective in treating the debilitating immune system disorder."" The focus of the story is FDA approval of the new drug. The headline explains that the FDA approved the first new drug for lupus in 56 years. It’s clear the story did not rely solely on a news release." Claim: FDA approves first new drug for lupus in 56 years

Ex Output:
"Good caveats, including in the patient profiled, who said, ""It’s a bittersweet thing for me because I have friends with lupus for whom this drug won’t work. There’s no one-size-fits-all for lupus and I’m just extremely fortunate that my lupus is mild and is helped by Benlysta."" The story should have discussed potential harms and costs. As the story explained, this was not only the first new lupus drug approved in 56 years, but it could be ""a milestone that medical experts say could prompt development of other drugs that are even more effective in treating the debilitating immune system disorder."""


Ex Input:
Paragraph: In recent decades, laughter has been touted as a possible cure for many ills, including cancer and heart trouble. But could mirth also be deadly, making the phrase “I just about died laughing” as much about accuracy as it is hyperbole? On 24 March 1975, 50-year-old bricklayer Alex Mitchell of King’s Lynn in Norfolk, England, kicked the bucket while roaring with laughter at one of his favorite television shows, the comedy program The Goodies. The skit that precipitated Mitchell’s fatal fit of glee involved a kilted Scotsman’s flailing away with his bagpipe at a vicious black pudding intent upon attacking him. Mitchell was unable to stop laughing, and after twenty-five minutes of uproar gave one last “tremendous belly laugh, slumped on the settee, and died,” said his widow, who witnessed his passing. While Mitchell had expired from heart failure, what felled him was not a classic heart attack, but rather the result of an unusual inheritable heart rhythm disorder that routinely takes the lives of even apparently robust 20-somethings. Mitchell had Long QT syndrome, an affliction in which the heart is prone to experiencing long pauses between heart beats, especially after instances of excitement or exertion. After such an incident, the heart resets itself after a few beats, but in some cases (such as this) the person is not so fortunate. An odder account of a “dying laughing” incident was reported in Bangkok in 2003:  An ice cream truck driver in Thailand died while laughing in his sleep. Damnoen Saen-um, 52, laughed for about two minutes yesterday and then stopped breathing, The Nation newspaper reported. Damnoen’s wife tried to wake him up but he kept laughing. An autopsy suggested that he might have had a heart attack. “I have never seen a case like this. But it is possible that a person could have heart seizure while laughing or crying too hard in their sleep,” said Dr Somchai Chakrabhand, deputy director-general of the Mental Health Department. On the anecdotal side, Schott’s Original Miscellany attributes the death of Burmese king Nandabayin in 1599 to his having “laughed to death when informed, by a visiting Italian merchant, that Venice was a free state without a king.”  And on the fictional front, one version of the demise of Pecos Bill, the legendary cowboy hero of American folklore, has him dying from laughter after an encounter with a Boston dude:  When Bill was gettin’ on in years, a Boston man came down to New Mexico for a visit. He fancied himself a bit of a cowboy. Got himself one of them mail-order suits, don’t ya know. The ones with the lizard skin boots, a shiny brass belt buckle, a new pair of blue jeans and a huge ten gallon hat with not a speck of dust on it. Well, when Pecos Bill saw him trying to swagger into a bar, he jest lay down on the sidewalk and laughed himself to death! Not enough information was given in the (real) cases cited above to know whether laughter was a coincidental, contributory, or causal element of the deaths, but linguistically we’ve been tossing about “dying laughing” expressions for centuries; the Oxford English Dictionary records a use of this phrase as far back as 1596 (“Went they not quickly, I should die with laughing”). We also employ similar phrases to indicate intense feelings of humiliation (“I almost died of embarrassment”), and in a more generic sense we use ‘dying’ to indicate great longing (“I’m just dying to see you”) or excellence (“It’s to die for”). It therefore comes as a bit of a shocker to realize that there might be at least a smidgen of truth buried deep beneath all this overblown emoting. Claim: People have died laughing.

Ex Output:
Yet even if there may have been an occasional death from guffawing, it’s still possible merriment is far more healthy than harmful (at least for the ones who survive). Some studies assert laughing produces beneficial effects on physical health, including decreasing the secretion of serum cortisol (a stress hormone) and boosting the blood levels of immunoglobulin A, an antibody that fights bacterial and viral infections in the upper respiratory and gastrointestinal tracts. However, not everyone in the scientific community has jumped on this bandwagon: in a study reported upon in 2002 in Current Directions in Psychological Science (“Is Laughter the Best Medicine? Humor, Laughter, and Physical Health)  researchers reported that the connection between humor and wellness was “less conclusive than commonly believed” and that “future research in this area needs to be more theoretically driven and methodologically rigorous.”


Ex Input:
Paragraph: More than 336,000 cases of chlamydia, gonorrhea and syphilis were reported last year, as rates of all three STDs continued to increase across the state, the California Department of Public Health reported. Officials said they are particularly concerned by the number of congenital syphilis cases, which were 14% higher than the previous year and nearly 900% higher than in 2012. There were 22 stillbirths or neonatal deaths because of syphilis last year, the report said. If left untreated, syphilis can result in blindness, hearing loss and neurological problems. Chlamydia and gonorrhea can lead to infertility, ectopic pregnancy and chronic pelvic pain. Many STDs can be cured with antibiotics. The highest rates of STDs are among young people ages 15 to 24, officials said. The department’s acting director, Dr. Charity Dean, urged sexually active people to use condoms and get tested. “Regular testing and treatment are essential prevention strategies, even for people who have no symptoms,” Dean said in a statement. “Most people infected with an STD do not know it.” State officials are collaborating with local agencies to coordinate efforts to control STDs, the health department said. Claim: Report finds cases of STDs reach 30-year high in California.

Ex Output:

The number of cases of three major sexually transmitted diseases in California reached a 30-year high in 2018, according to a state report released Tuesday.