Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
Central pontine myelinolysis manifested by temporary blindness: a possible complication of lithium toxicity.

Ex Output:
adverse drug event


Ex Input:
Intravenous injection of diazepam caused a rapid normalization of the EEG with disappearance of the clinical manifestations.

Ex Output:
non-adverse drug event


Ex Input:
Pramipexole is a Food and Drug Administration-approved antiparkinsonian agent, which, when used to augment antidepressants, would be considered an off-label use and should be discussed with the patient.

Ex Output:

non-adverse drug event