TASK DEFINITION: In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
PROBLEM: Paragraph: Annotation The process of adding descriptive information to a data set and the individual data elements that comprise that data set. May include both computational analyses and manual curation. Curation The process of manually adding descriptive information or explanatory material to a data set usually based on a review of the existing literature. Database A collection of information, usually stored electronically on a computer. Database, hierarchical (XML) Extensible markup language. A formally defined hierarchical organization of data. A database software package designed to operate on a particular computer platform and operating system. Database schema A map of the database structure, including all of the fields, tables, and relationships that comprise the framework for storage of information within that database. Database, relational A database structure that provides the ability to define formal relationships between all data elements stored within the database. Ontology A controlled vocabulary used to formally describe (for our purposes) a biological process or entity. SQL Structured Query Language. A computer language used to query relational databases for information. 
 Title: Virus Databases

SOLUTION: False

PROBLEM: Paragraph: The observations that Lymphopenia is common in severe acute respiratory syndrome (SARS) patients and that peripheral blood mononuclear cell (PBMC) could be infected by SARS-CoV indicate that PBMC could be useful in identifying the gene expression profile in convalescent patients and tracing the host response to SARS-CoV infection. In this study, the altered genes expressions in the PBMC of convalescent SARS patients were investigated with suppression subtractive hybridization (SSH). We found that genes encoded by mitochondrial DNA (mtDNA) were obviously upregulated, while mitochondria were now found to be closely connected with antiviral immunity. The identification of a viral gene, M, in SSH cDNA library shows the long-term existence of SARS-CoV in vivo. In addition, some oxidative stress sensitive genes, heat shock proteins, transcription factors, and cytokines showed remarkable elevation. Thin-section electron microscope shows increased lysosome-like granule and mitochondria in PBMC of patients. These results provide important intracellular clue for tracing host response to SARS-CoV infection and suggest a role of mitochondria in that process. 
 Title: Upregulation of Mitochondrial Gene Expression in PBMC from Convalescent SARS Patients

SOLUTION: True

PROBLEM: Paragraph: Timely detection of an inhalational anthrax outbreak is critical for clinical and public health management. Syndromic surveillance has received considerable investment, but little is known about how it will perform relative to routine clinical case finding for detection of an inhalational anthrax outbreak. We conducted a simulation study to compare clinical case finding with syndromic surveillance for detection of an outbreak of inhalational anthrax. After simulated release of 1 kg of anthrax spores, the proportion of outbreaks detected first by syndromic surveillance was 0.59 at a specificity of 0.9 and 0.28 at a specificity of 0.975. The mean detection benefit of syndromic surveillance was 1.0 day at a specificity of 0.9 and 0.32 days at a specificity of 0.975. When syndromic surveillance was sufficiently sensitive to detect a substantial proportion of outbreaks before clinical case finding, it generated frequent false alarms. 
 Title: Evaluating Detection of an Inhalational Anthrax Outbreak Detecting an Inhalational Anthrax Outbreak Emerging Infectious Diseases • www Detecting an Inhalational Anthrax Outbreak Emerging Infectious Diseases • www

SOLUTION:
True