Turn the given fact into a question by a simple rearrangement of words. This typically involves replacing some part of the given fact with a WH word. For example, replacing the subject of the provided fact with the word "what" can form a valid question. Don't be creative! You just need to rearrange the words to turn the fact into a question - easy! Don't just randomly remove a word from the given fact to form a question. Remember that your question must evaluate scientific understanding. Pick a word or a phrase in the given fact to be the correct answer, then make the rest of the question. You can also form a question without any WH words. For example, "A radio converts electricity into?"

Q: Fact: Vaccination leads to immunity and extremely rarely with serious side effects.

A: What leads to immunity and extremely rarely with serious side effects?
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Q: Fact: Wildfires are caused by lightning.

A: What causes wildfires?
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Q: Fact: All chemical reactions require the initial input of energy to get the reaction started.

A:
All chemical reactions require the initial input of energy to get the reaction what?
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