instruction:
Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.
question:
Paragraph: WTOP-FM reports that the Fairfax County Fire and Rescue Department is partnering with the National Fire Protection Association Research Foundation on a four-phase study. Part of the focus of the study will be on how chemicals can cling to breathing equipment used by firefighters. Firefighters are exposed to toxic chemicals released into the air by burning buildings and vehicles. According to a National Institute for Occupational Safety and Health study, firefighters are twice as likely to get skin and testicular cancer and mesothelioma. ___ Information from: WTOP-FM, http://www.wtop.com Claim: Firefighters study carcinogen exposure.
answer:
Firefighters in Virginia are taking part in a study aimed at finding ways to reduce their exposure to carcinogens.


question:
Paragraph: The mosquito-borne viral infection has spread across the country, with 61 out of 64 districts reporting dengue cases by late Tuesday. The government has confirmed 15,369 dengue cases since Jan. 1. Of those, 9,683 patients were diagnosed between July 1 and July 30. As of Tuesday, about 4,400 patients, including many children, were undergoing hospital treatment. There have been 14 deaths. Officials from Dhaka, the overcrowded capital and the epicenter of the outbreak, have struggled to contain it, drawing criticism and spreading panic among some residents. Dengue is found in tropical areas around the world and is spread by a type of mosquito that mainly lives in urban areas. The virus causes severe flu-like symptoms, and while there is no specific treatment for the illness, medical care to maintain a person’s fluid levels is seen as critical. There are fears that the situation in the countryside will worsen as many residents of the city travel to villages to celebrate Eid-ul-Adha next month. Infected humans can serve as a source of the virus for uninfected mosquitoes. Ayesha Akhter, assistant director at the Directorate General of Health Services under the Ministry of Health, said an outbreak of dengue has accompanied every monsoon since 2000, but this year’s situation is the worst. A DGHS study identified a six-fold increase in the Aedes aegypti mosquito population in four months in Dhaka as the primary cause of the larger-than-average outbreak. Earlier this month, the World Health Organization said the dengue situation in Bangladesh was “alarming but not out of control.” Other countries in Asia are also facing a surge in dengue cases this year, including Thailand, where 53,699 cases and 65 deaths were reported as of July 23. Nevertheless, with dengue cases soaring in recent weeks, Dhaka hospitals have been running out of room and manpower to treat new patients. Prof. Abul Kalam Azad, director general of DGHS, said they had asked the hospitals to increase beds for dengue patients and to open dengue wards. The government also halved the charges for diagnosing dengue and directed public and private hospitals, clinics and diagnostic centers to do the same. Dhaka Medical College Hospital, the largest hospital in the country, opened a special ward for dengue patients, said A.K.M. Nasir Uddin, its director general. Prof. Uttam Kumar Barua, director of Shaheed Suhrawardy Medical College and Hospital, another major public hospital in Dhaka, said they were relying on senior medical students to assist doctors in the face of so many patients. “We don’t have manpower, logistic support and technicians as much as needed. That’s why we are having too much pressure. We have three times more patients than our bed capacity,” Barua said. He said they were admitting every dengue patient who entered the hospital but could not provide beds or even seats for everyone, adding that many had been asked to wait in hospital corridors and verandas. Champa Begum took her 8-month-old to Shaheed hospital on Wednesday. “I have other kids. I go to work leaving this one to another child. I have no way but to work,” she said. “I can’t take care of this child properly. This child is laid down anywhere. My home is above dirty water. That how this one was bitten and got dengue.” On Tuesday, Bangladeshi Prime Minister Sheikh Hasina called for concerted efforts to fight the illness. “The government is working to tackle dengue,” she told an emergency meeting of her ruling Awami League party via teleconference from London, where she was on an official visit. “I urge everyone to keep their houses and surrounding areas clean. That will save us from the disease,” she said. The country’s opposition parties and urban planning experts blamed the central and local government’s lack of preparedness for the rise in dengue cases. People have taken to Facebook to vent their anger about city authorities’ failure to control dengue-carrying mosquitoes. Claim: Bangladesh grapples with country’s worst dengue outbreak.
answer:
Bangladesh is facing its worst-ever dengue fever outbreak as hospitals are flooded with patients, putting a severe strain on the country’s already overwhelmed medical system.


question:
Paragraph: Costs of either new treatment approach are not discussed, nor whether they might be covered by insurance. Since the first-ever clinical trial of stem cells to regrow cartilage pads is ongoing, benefits cannot be quantified. A similar challenge in reporting benefits of cartilage plugs is that this approach doesn’t appear to have any studies that support its use in cartilage (vs. bone), since this is an off-label use. While benefits aren’t reported, it doesn’t appear that there are any to actually describe just yet. The stem cell technique is quoted by the lead researcher as having “no safety problems.” While this is suspect, since this is the first clinical trial, side effects or harms in humans may not be known. The article could have countered this quote with a statement that no side effects have been reported yet, which is different than that they don’t exist. A potential harm talked about by someone not apparently involved in the research is that too much cartilage may be re-grown and there may not be a mechanism to turn it off, leading to unforeseen problems. For the cartilage plugs, harms of treatment are not discussed, although a question about their benefit–whether they even work in cartilage–is raised. The story describes on-going research using stem cells to re-grow the cartilage pad, or meniscus, in the knee. The ongoing research is described as a clinical trial, with either a “dummy” or active injection given to patients (so there is a placebo or control group and this also implies patients don’t know which one they’ve received, or that they’re “blinded” to the intervention), and that researchers are blinded to which intervention patients have received. What’s described is a randomized, controlled trial, which is the gold-standard in research. The other technique–cartilage plugs–is being used for treatment that doesn’t appear to have any research to support it, or at least not when used in cartilage (vs. bones). But, the article describes these circumstances to readers. The article provides a brief overview of knee injury or disease (arthritis) and the numbers of people who experience this. The article nicely states that the “holy grail” is repairing the cartilage of knee bones associated with arthritis – typically age-related wear and tear. None of the treatments mentioned are anywhere near this. So for current patients suffering from knee pain due to degenerative arthritis, the options are conservative medicines (like ibuprofen) or knee replacement surgery. This article suggests an intermediate, less invasive approach. The current cartilage repair procedures aren’t thought to work very well (thus the search for new ones). These aren’t the first attempts to repair cartilage. Others have been tried, but generally haven’t offered much benefit to patients. For the stem cell research, the article does quote a source who is apparently uninvolved with the research. This source provides some balance in noting that it’s not clear whether this works, and specifically, whether this process can be turned off once enough cartilage is re-grown. For cartilage plugs, the same source comments with skepticism over whether these really work. Currently, the standard treatment option for meniscus tears is surgical removal of jagged edges that don’t heal, which is mentioned in the story. Treatment alternatives for injured or damaged articular cartilage (vs. use of articular plugs) are described and include total knee replacement and surgery to “rough up” the edges to stimulate natural repair. Framing around what these new treatments hope to provide could have been improved, e.g. many of the intermediate procedures talked about in the article are trying to provide an option in the middle of either a very simple approach, like medications, or a pretty aggressive approach, like joint replacement. There are two treatment options discussed in the article. One uses stem cells from donated bone marrow. This technique is reported as part of the first-ever clinical trial using stem cells to regrow a cartilage pad in the knee, so readers know this option is not available yet outside of this research study. The second treatment approach uses cartilage plugs to fill in gaps or injuries to knee cartilage. The story states these cartilage plugs are FDA-approved for use in bones, but not cartilage, so the use described is “off-label.” The article describes the stem cell option as new, which does appear to be true. It also describes the off-label use of cartilage plugs, implying this technique itself may not be new, but is being used in a new capacity. There have been prior attempts to repair cartilage that are not mentioned in the article, but these attempts have not provided much benefit. There is no obvious reliance on press release material. Claim: Doctors Test Ways to Grow Knee Cartilage
answer:

The article describes two potential treatments for knee problems: using stem cells donated from bone marrow to re-grow cartilage pads and using cartilage plugs, approved for use in bone, to fill in gaps in cartilage. The story does a good job of describing the evidence (either an ongoing clinical trial using stem cells to re-grow cartilage pads or the fact that cartilage plugs are an “off-label” use of an existing technology), although there are limitations to what we know or will know, which could have been clearer. For example, although the first-ever clinical trial of stem cells is ongoing, the number of participants is small and more studies will be needed before this would become widely available. The description of harms of either of these approaches could have been improved. For instance, letting a quote by the lead researcher (who has a conflict of interest) stand stating that there are no safety problems with the stem cell technique is a bit misleading. It’s hard to believe there would be no side effects at all and the fact that this is new technology and that harms may not be known is different than they don’t exist, which is implied. Yet the topic is an important one because better treatments for age-related arthritis of the knee are needed. Unfortunately, the techniques discussed in this article are only precursors of the types of treatments that may help the large number of older individuals suffering from knee arthritis. Even if these treatments provide benefit and are approved for use by the FDA, it will require future studies and many more years to bring successful treatments to the average patient.