instruction:
Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
question:
Context: Common cellular and molecular mechanisms including protein aggregation and inclusion body formation are involved in many neurodegenerative diseases. -Synuclein is a major component of Lewy bodies in Parkinson's disease (PD) as well as in glial cytoplasmic inclusions in multiple system atrophy (MSA). Tau is a principal component of neurofibrillary and glial tangles in tauopathies. Recently, TDP-43 was identified as a component of ubiquitinated inclusions in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. PD is traditionally considered a movement disorder with hallmark lesions in the brainstem pigmented nuclei. However, pathological changes occur in widespread regions of the central and peripheral nervous systems in this disease. Furthermore, primary glial involvement ("gliodegeneration") can be observed in PD and MSA as well as in tauopathy. The present article reviews abnormal protein accumulation and inclusion body formation inside and outside the central nervous system. 
 Question: Which is the primary protein component of Lewy bodies?
answer:
αsyn


question:
Context: Mutations of SLC9A6 may cause an X-linked clinical syndrome first described by Christianson in 1999 in which affected males exhibited profound intellectual disability, autism, drug-resistant epilepsy, ophthalmoplegia, mild craniofacial dysmorphism, microcephaly, and ataxia. We describe a child with an SLC9A6 mutation and an electroencephalographic pattern consistent with electrographic status epilepticus of sleep. Our patient's electrographic status epilepticus of sleep resolved after treatment with felbamate. Following treatment, he remained seizure-free but did not make significant or lasting gains in language. Our report extends the clinical epilepsy phenotype in children with SLC9A6 mutations to include electrographic status epilepticus of sleep. In addition, felbamate was an effective treatment for electrographic status epilepticus of sleep in our patient. 
 Question: Mutation of which gene is implicated in the Christianson syndrome?
answer:
slc9a6


question:
Context: There are about 27,000 species of bony fish ( Figure 1.1), which are divided into two classes: ray-finned fish and lobe-finned fish. Most bony fish are ray-finned. These thin fins consist of webs of skin over flexible spines. Lobe- finned fish, on the other hand, have fins that resemble stump-like appendages. Fins of bony fish: ray fin (left) and lobe fin (right). Most fish are bony fish, making them the largest group of vertebrates in existence today. They are characterized by: 1. A head and pectoral girdles (arches supporting the forelimbs) that are covered with bones derived from the skin. 2. A lung or swim bladder, which helps the body create a balance between sinking and floating by either filling up with or emitting gases such as oxygen. Controlling the volume of this organ helps fish control their depth. 3. Jointed, segmented rods supporting the fins. 4. A cover over the gill called the operculum, which helps them breathe without having to swim. 5. The ability to see in color, unlike most other fish. Most vertebrates are ray-finned fish, with close to 27,000 known species. By comparison, there are "only" about 10,000 species of birds. The ray-finned fish have fin rays, with fins supported by bony spines known as rays. The ray-finned fish are the dominant class of vertebrates, with nearly 99% of fish falling into this category. They live in all aquatic environments, from freshwater and marine environments from the deep sea to the highest mountain streams. The lobe-finned fish are characterized by fleshy lobed fins, as opposed to the bony fins of the ray-finned fish. There are two types of living lobe-finned fish: the coelacanths and the lungfish. The pectoral and pelvic fins have joints resembling those of tetrapod (four-limbed land vertebrates) limbs. These fins evolved into legs of amphibians, the first tetrapod land vertebrates. They also possess two dorsal fins with separate bases, as opposed to the single dorsal fin of ray-finned fish. All lobe-finned fishes possess teeth covered with true enamel. The lungfish also possess both gills and lungs, solidifying this class as the ancestors of amphibians. The ocean sunfish is the most massive bony fish in the world, up to 11 feet long and weighing up to 5,070 pounds ( Figure 1.2). Other very large bony fish include the Atlantic blue marlin, the black marlin, some sturgeon species, the giant grouper, and the goliath grouper. The long-bodied oarfish can easily be over 30 feet long, but is not nearly as massive as the ocean sunfish. In contrast, the dwarf pygmy goby measures only 0.6 inches. Fish can also be quite valuable. In January 2013, at an auction in Tokyos Tsukiji fish market, a 222-kilogram (489-pound) tuna caught off northeastern Japan sold for 155.4 million yen, which is $1,760,000. An ocean sunfish, the most massive bony fish in the world, can reach up to 11 feet long and weigh up to 5,070 pounds! 
 Question: most fish are what type?
answer:

ray-finned fish