Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

[Q]: Paragraph: The Nobel Assembly, which awarded the prize of 8 million Swedish crowns ($1.1 million) at Sweden’s Karolinska Institute on Monday, said the discovery solved a problem that had occupied philosophers and scientists for centuries:  “How does the brain create a map of the space surrounding us and how can we navigate our way through a complex environment?”   Ole Kiehn, a Nobel committee member and professor in Karolinska’s neuroscience department, said the three scientists had found “an inner GPS that makes it possible to know where we are and find our way”. O’Keefe, now director at the center in neural circuits and behavior at University College London (UCL), discovered the first element of the positioning system in 1971 when he found that a type of nerve cell in a brain region called the hippocampus was always activated when a rat was in a certain place in a room. Seeing that other nerve cells were activated when the rat was in other positions, O´Keefe concluded that these “place cells” formed a map of the room. Uta Frith, a UCL professor of cognitive development said O’Keefe had shown “it is possible to literally map the mind”. “He has done much more than discovering neuronal mechanisms in the brain: he has discovered cognitive mechanisms that explain how human beings and other animals navigate,” she said. “This beautiful work is heralding a new age of exploration of brain and mind.”  In 1996, Edvard Moser and May-Britt Moser, who are married and now based in scientific institutes in the Norwegian town of Trondheim, worked with O’Keefe to learn how to record the activity of cells in the hippocampus. Nearly a decade later, the Moser team discovered cells, in the entorhinal cortex region in brains of rats, which function as a navigation system. These so-called “grid cells”, they discovered, are constantly working to create a map of the outside world and are responsible for animals’ knowing where they are, where they have been, and where they are going. Bill Harris, head of physiology, development and neuroscience at Britain’s University of Cambridge, said the scientists’ work “has not only revolutionized our understanding of this amazing puzzle (the brain), but has also opened the door into problems of place memory and how we learn and remember routes of navigation, and what sleep and dreams may be doing for memory and performance.”  While the findings help explain how the brain works, they have no immediate implications for new medicines or other therapies, since they do not set out a mechanism of action. But knowledge about the brain’s positioning system can also help understanding of what causes loss of spatial awareness in stroke patients or those with devastating brain diseases like dementia, of which Alzheimer’s is the most common form and which affects 44 million people worldwide. O’Keefe told reporters in London he was very surprised to get the Nobel Prize, particularly after what he described as a “checkered youth” jumping from studying classics at school, then aeronautics at college before getting into philosophy and psychology. “I’m still in a state of shock,” he said. May-Britt Moser danced and drank champagne with her colleagues in Trondheim after she was told of the award. “This is so great, this is crazy. I am just jumping, screaming,” Moser told Reuters. “I am so proud of all the support that we have had. People have believed in us, in what we have been doing and now this is the reward.”  Norwegian TV showed her co-workers singing “Happy Nobel to you” to the tune of “Happy Birthday”. Her husband did not immediately learn that he had won the Nobel Prize as he was on a plane bound to Munich. Someone was waiting for him at Munich airport with flowers and gave him the news, he told the Norwegian news agency NTB. The Mosers join a small club of married couples to win a Nobel Prize that includes Pierre Curie and Marie Curie. John Stein, an emeritus professor of physiology at Oxford said that, as with so many Nobel Prize winners, the scientists’ discovery was at first ridiculed and dismissed, only later to get the recognition it warrants  “This is great news and well deserved,” Stein said. “I remember how great was the scoffing in the early 1970s when John first described ‘place cells’. ‘Bound to be an artefact’ and ‘he clearly underestimates rats’ sense of smell’ were typical reactions. Now, like so many ideas that were at first highly controversial, people say: ‘Well that’s obvious’!”      Medicine is the first of the Nobel Prizes awarded each year. Prizes for achievements in science, literature and peace were  first awarded in 1901 in accordance with the will of dynamite  inventor and businessman Alfred Nobel. (1 US dollar = 7.2230 Swedish crown) Claim: Nobel Prize for medicine goes to discoverers of brain’s 'inner GPS'.
[A]: British-American John O’Keefe and Norwegians May-Britt and Edvard Moser won the 2014 Nobel Prize for medicine for discovering the brain’s navigation system and giving clues as to how strokes and Alzheimer’s disrupt it.


[Q]: Paragraph: Dr. Neelu Pal poses for a portrait in New York, July 23, 2010. Pal was fired weeks after authorities at New York University Langone Medical Center Surgical Weight Loss Program learned she had contacted patients about the dangers of Lap-Band surgery in January 2006. REUTERS/Shannon Stapleton Pal had previously raised her concerns with hospital officials, complaining — to no avail — about the lack of care given after surgery and incomplete or inaccurate medical forms that were taken prior to surgery. She was fired weeks after hospital authorities learned she had contacted patients in January 2006. She has filed a wrongful termination lawsuit — the case is pending — and enrolled in law school. Pal, who came to the United States from India a little over a decade ago to practice medicine, says she has been blackballed from her chosen profession. The NYU bariatric surgery practice where she worked is widely considered one of the world’s most experienced. But in an interview with Reuters, Pal described the facility as a hectic Lap-Band factory. “My impression at the time was that the practice was disorganized, but once I knew more about the system, I could see what they were trying to do was get as many patients on to the operating table as possible,” she said. During her three months at NYU Langone Medical Center’s Surgical Weight Loss Program in late 2005 and early 2006, two surgeons — Dr. Christine Ren and Dr. George Fielding, who are married — implanted gastric bands into as many as 20 patients in a single day, according to Pal. Known as pioneers in the field, Fielding and Ren are also paid consultants of Allergan Inc, the Botox and breast implant maker which is the leading manufacturer of the gastric band. Though rivals have been gaining, Allergan’s Lap-Band still commands more than two-thirds of a $300 million to $400 million market. To critics, Pal’s allegations — some of which were corroborated by a New York State Health Department investigation around that time — underline the potential risks that go along with the industry’s rapid growth. And the business could soon swell even more if U.S. regulators grant permission to perform the procedure on the nation’s bulging ranks of overweight teens. Ren was an investigator in an Allergan-sponsored clinical trial studying the use of bands on teens. And the company has an application with the U.S. Food and Drug Administration seeking approval to market the device to teens as young as 14. A decision could come any time. Winning regulatory approval for the gastric band in teenagers would allow the companies that make the devices — Allergan, Johnson & Johnson and others — to target that specific age group. Today, regulators consider performing the procedure on teens “experimental” as it has not been approved for that age group. But, like any device, it may be used on teens at a doctor’s discretion. Allergan declined to comment on Pal’s lawsuit or disclose how much it pays the surgeons, though the company did confirm that both remain on the payroll. Through a NYU spokeswoman, Ren and Fielding — who have been the subject of some controversy — declined to be interviewed for this article, also citing the lawsuit. But in some medical circles, concern over gastric banding for teenagers is growing nearly as fast as American waistlines. In particular, some doctors worry about the device’s long-term safety and effectiveness. A gastric band is just what it sounds like: an inflatable silicone band placed around the top portion of the stomach to create a pouch that restricts food intake. It has become increasingly popular in the United States in recent years, and results in reasonable weight loss. The procedure is considered less invasive and risky than gastric bypass. Banding could also be an especially attractive option for teens, say proponents, because it is reversible, whereas bypass is not. The 30- to 60-minute procedure, typically performed with a laparoscope, might require one night in the hospital but can also be done on an outpatient basis. But certain data show gastric bands are less effective and more problematic for teens than adults, said Dr. Thomas Inge, chair of a government study to assess bariatric surgery in adolescents called Teen Longitudinal Assessment of Bariatric Surgery, or Teen-LABS for short. The Teen-LABS study aims to determine if adolescence is the best time to intervene with surgery. It was launched in 2007 and is expected to report results in about five years. In more than one in five teens in another study, Inge noted a high rate of “symmetric pouch dilation” — a complication in which the small pouch created at the top of the stomach by the band gets bigger, allowing patients to consume more food. This issue was reported in the journal Obesity Surgery, and later in the Journal of the American Medical Association. “We await the U.S. trial data, PMS (post-marketing surveillance) data, and confirmation from non-industry-run trials to make final recommendations,” said Inge, who is the surgical director of the weight loss program for teens at Cincinnati Children’s Hospital. As Inge and others are quick to point out, trials that studied how teens fared with a gastric band over the short term have been few, and those that were conducted show the device generally is safe and effective, with a relatively low risk for complications or death. But there is a dearth of long-term data on the outcomes from gastric band surgery. And that worries Dr. Mary Brandt, an investigator in the Teen-LABS study, among other experts. “I think there’s a fundamental problem with putting a rigid plastic object around a moving organ. You’re asking it to stay in place and not erode over a long period of time,” said Brandt, who is also director of the pediatric surgical program at Texas Children’s Hospital in Houston. “I’ll be happy to reverse my position as soon as I see 10 or 20 year data. Unfortunately, that’s not something that industry is excited about funding.”   She acknowledged a bias against gastric bands, citing a Swiss long-term follow-up study of 167 adults that showed the band failed almost a third of the time after 10 years. About a fifth of the patients required another operation. And while fewer than 8 percent reported complications in the 30 days following surgery, more than 40 percent had problems after a decade. Long-term complications included the erosion and slippage of the band, both of which might require another operation, and a dilation of the esophagus, which could result in difficulty swallowing. Infections around the port that sits below the skin and allows the doctor to add or remove saline with a syringe to tighten or loosen the band, as well as leaks, were also common. “Bands are definitely safe in the short term and definitely work in the short term. What we don’t know is about the long term,” Brandt said. “I’m not saying it should never be used. We just have to be more careful about how we’re using it.”   The Swiss study of adults who had gastric banding, published in Obesity Surgery, came to the same conclusion. Because of complications, the need for another operation, and long-term failure rates, gastric banding should be performed in “selected cases only” until more data are available, it said. Another group of 276 adults who underwent gastric band surgery had similarly disappointing results in a long-term Austrian study published in the same journal. Only a little under 54 percent of the patients still had their original band after nine years, with nearly 18 percent having the original replaced with a new one and nearly 29 percent having it removed. Of those who no longer had any band, more than half had a second bariatric operation. Gastric banding demands that teens do something they often aren’t very good at — sticking to a rigorous follow-up routine. Dr. Roberta Maller Hartman, a psychologist and Lap-Band patient herself, counsels teens and adults after receiving the gastric band. “I’ve worked with a lot of high school students and they just want to be like everyone else and go out and eat pizza with their friends,” she said. “They can, but they have to take little bites and chew a lot.”   Success depends most on a patient’s ability to modify their behavior. “The band doesn’t reduce the desire to eat emotionally. That has to be addressed,” said Dr. Maller. “Teens tend to need more hands-on, one-to-one support.”   Indeed, there are many success stories of obese teens losing weight, keeping it off and staving off a host of related illnesses, such as diabetes, arthritis and high blood pressure. Surgery — banding or bypass — has been shown to produce the most sustainable results when compared with diet and exercise. Nevertheless, critics abound. Dr. Susan Woolford, Medical Director of the Pediatric Comprehensive Weight Management Center at the University of Michigan, conducted a study, published in Obesity Surgery, to find out how readily primary care physicians and pediatricians — those in the front lines of obesity treatment — would refer patients for bariatric surgery. Nearly half, or 48 percent of the 381 physicians surveyed, said they would never refer an adolescent for any type of bariatric surgery. The controversies swirling around NYU’s influential bariatric surgery center — as well as its two top surgeons — have done little to ease concerns. An investigation by the New York State Department of Health in 2006 found that Fielding falsified data on Vincent Esposito, a 14-year-old boy who was part of the FDA-authorized study that was looking at the use of the device in obese teens. A week after Esposito’s Lap-Band surgery, he developed an infection with an abscess — a common complication with gastric banding — and returned to the NYU facility, where Fielding performed an appendectomy. The investigation by New York health authorities determined there was no evidence of appendicitis, according to the report. “They told me I was a ticking bomb,” Esposito had told the Daily Times in Salisbury, Maryland in 2007, referring to his obesity. Reached by telephone, his father said his son was “fine” and that they are being represented by an attorney and declined to comment. NYU also declined to comment. In its response to the NYDH report, the university maintained no wrongdoing, saying “the surgeon probably misinterpreted his operative findings.” In a statement at the time, the school added, “...we are persuaded that he assumed that the infection did not begin in the gastric band device.”   The response and NYU’s plan to correct the issues were accepted by state regulators. In the NYSHD report, Fielding was also cited for failing to address a post-operative patient’s persistent lack of urine output. The patient went into cardiac arrest and died 36 hours later. This was the death that alarmed Pal and led her to warn patients. The same report said the program director, Ren, had permitted two surgeons to practice without the appropriate licenses, in violation of the law. For four months, the unlicensed physicians “performed multiple surgical procedures, made pre- and post-op assessments, and wrote orders to be carried out by nursing staff,” the report said. After Ren learned she was being investigated by an internal committee, she went back and removed the name of the unlicensed surgeon from the operative report, according to court testimony. She was found to have committed professional misconduct and received a letter of reprimand that was put in her file for a year. Fielding, who got a gastric band himself in 1999, is from Australia, where he left behind multiple personal injury lawsuits, most of which have been settled. Dr. Robert “Skip” Nelson, a pediatric ethicist at FDA, said he had no specific knowledge about the incident at NYU Medical Center. If the agency did learn that an investigator has entered false data, he said, there would be an investigation. He added that if the FDA doubted the integrity of the data, they would not be considered in the decision-making process. An investigator, as doctors who run clinical trials are called, could also be disqualified as a result. Despite the reports of misconduct, the NYU Langone Weight Management Program has retained its status as a “Center of Excellence,” a designation conferred by the Surgical Review Corp, an entity created by the American Society for Bariatric and Metabolic Surgery. Surgical Review Corp CEO Gary Pratt said that he was unaware of the incidents and the NYSHD report. He said the corporation’s reviews maintain the highest standards with the goal of advancing the safety and efficacy of bariatric surgery. The company intends to put out a new list of approved bariatric clinics that treat teens later this year — which may coincide with the FDA granting approval, or not. If the FDA does greenlight it, insurers would be more likely to pay for the procedure, which costs the insured patient $2,000 to $4,000. The uninsured, making up about a third of patients who have the surgery in the United States, pay about $15,000 for the surgery. Some health professionals worry that band manufacturers will target teens with direct-to-consumer (DTC) ads on television and radio or in subway stations that have proven effective at luring people to doctors’ offices. The FDA said there is no guidance or regulation on DTC ads to young users. For Allergan, based in Irvine, California, the implications are significant. And the company is acting accordingly. It recently launched a campaign with bariatric surgeons to invite their patients to enter an essay contest and win a chance to go to Washington, D.C. to “share their personal stories with legislators and media.”   Allergan has seen its stock underperform the S&P 500 year to date. Botox remains its key product and has weathered increased competition amid the recession, while obesity intervention was hit hardest by the economy. At the same time, Lap-Band has also been slowly losing market share to Johnson & Johnson’s competing device called Realize. In 2009, Allergan’s obesity products generated revenue of $258 million, down 13 percent from 2008. Management is betting that continued investment in direct-to-consumer advertising will stimulate growth in the obesity segment, said Gleacher & Co analyst Amit Hazan. He estimates there will be 83,500 gastric band procedures in the United States in 2010, up 6 percent from 2009. Sanford Bernstein analyst Aaron Gal said FDA approval of the Lap-Band for teens could increase sales by as much as $20 million for Allergan. Even critics of gastric band surgery acknowledge that there are few good solutions to adolescent obesity. It is a mounting problem, affecting nearly 1 in 5 American teens, and many doctors believe that it should be addressed sooner rather than later when other health problems can develop. Some experts are wary but believe the benefits may outweigh the potential harm. “My conclusion is that it makes sense to intervene sooner because surgery can head off other related problems. Kids are better surgical risks, but the downside is that I suspect most teenagers are doing it less for health and more for social and psychological reasons,” said Dr. Jeffrey Zitsman, who is leading an independently funded teen study at Columbia University. Those who do it out of vanity, he cautioned, may have a harder time. “When health reasons don’t motivate them,” he said, “sometimes there are compliance issues.”   Yet, Dr. Robert Murray, director of Nationwide Children’s Hospital Center for Healthy Weight and Nutrition, argues that the heavy psychological problems obese teens carry should not be ignored. “They’ve been teased out of school, they have social issues, many are depressed, and their quality of life is equal to that of a kid with cancer,” he said. “If you get them at 14 and reverse weight and health problems, they’ve got a shot at a normal life.”   To critics, at least, the question is at how big a price. Claim: Special report: Targeting teens for gastric bands.
[A]: After one patient died and others suffered serious complications following Lap-Band surgery, Dr. Neelu Pal had seen enough. A petite surgical resident now aged 40, she began quietly calling patients about to undergo the weight-loss procedure at New York University’s Medical Center, telling them she feared for their safety.


[Q]: Paragraph: "A claim about Dan Patrick by an organizer for Battleground Texas, the pro-Democratic group, rang a bell. In a June 10, 2014, interview on Bloomberg TV, Jeremy Bird said Patrick, the Houston state senator who dusted incumbent David Dewhurst in the May 2014 primary runoff for the Republican lieutenant governor nomination, has ""called immigration into Texas an invasion"" and ""said immigrants coming into Texas bring ‘third-world diseases.’ "" We looked into whether Patrick made these statements and, if so, whether facts backed them up. Patrick: ‘Stop the invasion’ Patrick, championing his desire to secure the Texas-Mexico border, has often called to stop ""the invasion,"" referring to individuals who cross the border without legal documentation. Spokeswoman Lynda Tran of Battleground Texas noted by email, Patrick has an undated online post in which he asks supporters to donate ""if you agree we must stop the illegal invasion!"" According to a January 2014 news story in the Dallas Morning News, Patrick and another GOP aspirant blasted Dewhurst in a Jan. 27 debate for not doing more to secure the Texas border from illegal immigration. ""The first question is to stop the invasion,"" Patrick said. ""Until you secure the border, you cannot address any other issues."" It wasn’t a new cry. A Feb. 24, 2006, Texas Observer story described Patrick, then waging his first Senate campaign, as blaming illegal immigrants for a rising crime rate, overcrowded schools, an overburdened health-care system and runaway growth in the state budget. ""The number one problem we are facing,"" the Observer quoted Patrick as saying, ""is the silent invasion of the border. We are being overrun. It is imperiling our safety."" More recently, Patrick shelved such language. A June 7, 2014, Texas Tribune news story said Patrick didn’t use the ""invasion"" term at that week’s Republican Party of Texas convention. Instead, the story said, he called on Republicans to reach out to Hispanic voters by telling them ""that we stand with them for the future of their family"" and that only the GOP would work to secure their communities. U.S. Border Patrol figures show its apprehensions of individuals crossing the country’s southern border declined 69 percent from a little over 1 million in the fiscal year running through September 2006 to nearly 328,000 five years later. But such apprehensions bumped up 27 percent, to 414,397,as of  two years later, in fiscal 2013, the agency says. Since 2011, there’s been a surge in people from countries other than Mexico, including many minors from Central America. ‘They are bringing Third World diseases’ The Observer story revealed Patrick’s claims about disease along the border, saying Patrick characterized illegal immigrants as walking pathogens. ""They are bringing Third World diseases with them,"" Patrick said, citing ""tuberculosis, malaria, polio and leprosy."" But the story quoted a physician, identified as Tim Metz, the top epidemiologist at the Texas Department of State Health Services, as saying there wasn’t a known case of polio in the Western Hemisphere when Patrick spoke ""and we haven't seen it in decades."" According to the Observer, Metz said malaria, a tropical disease spread by the anopheline mosquito, is easily treated and remains ""a rare disease in Texas and not a huge problem."" Leprosy, he said, is known today as Hansen's disease and ""we have no more than 50 cases a year that are reported, but it's not on the rise."" As for TB, the physician told the Observer, ""we'll have 1,500 or so cases in Texas this year, which might be a slight increase, but we've got very effective TB-control programs in every local health department in the state."" For our part, we didn’t identify anyone by the name of Tim Metz. When we asked the Texas Department of State Health Services for guidance, spokesman Chris Van Deusen said by email that Tom Betz (not Tim Metz) was at one time the manager of the agency’s Infectious Disease Surveillance and Epidemiology branch. Van Deusen didn’t directly speak to what Patrick reportedly said in 2006, but he indicated immigrants aren’t showing up as bringing most of the diseases listed by Patrick. Polio, Van Deusen said,  has been eradicated from the Western hemisphere and ""we don’t generally see cases in Texas. Van Deusen said about 100 cases of malaria are annually reported in the state. All are imported, he said, and it’s not spread person to person in Texas. ""It’s generally related to travel, either people from here visiting parts of the world where malaria is endemic or people from abroad visiting the U.S., rather than immigration,"" he said. Cases of Hansen’s disease -- or what has been called leprosy -- are reported, Van Deusen said, with one third related to armadillos; one third tied to ""old European families that have a genetic susceptibility;"" and one third ""related to immigration from areas of the world where the disease is more common, irrespective of the type of immigration."" In April 2014, Patrick suggested critics distort what he said in 2006. Patrick bridled after San Antonio Mayor Julian Castro said to him in an immigration debate aired by Univision and posted online by the Texas Tribune: ""You have talked about undocumented immigrants bringing third-world diseases including leprosy and polio to Texas. You have said that we’re seeing an illegal invasion from Mexico."" Patrick shot back that his comment about disease in 2006 was based on information distributed by the U.S. Centers for Disease Control indicating tuberculosis cases were up nationally and in Texas, ""particularly along the Texas-Mexico border--and those cases were coming from Latin America,"" Patrick said. A 2012 CDC tuberculosis fact sheet states the disease had decreased in prevalence nationally. Some 9,945 TB cases (an average of 3.2 cases per 100,000 persons) were reported, the sheet says, and the 2012 count was the lowest since national reporting of TB commenced in 1953. Still, Texas, California and Florida were among a few states with an average number of cases exceeding the national average, according to a map with the fact sheet. Van Deusen said about half the state’s decreasing number of TB cases show up in residents born abroad. ""TB often crops up in immigrant populations because of the nature of the disease where a person can be exposed to the bacteria but not develop active disease for many, many years,"" he wrote. ""In fact, the vast majority of people who get the tuberculosis bacteria in their body will never go on to develop active TB disease because their immune systems will keep the bacteria in check."" In the Univision debate, Patrick said he’d previously mentioned leprosy because the World Health Organization reported that from 2010 to 2012, cases increased in Mexico and the U.S. An online search led us to a WHO chart indicating U.S. cases of leprosy increased from 169 in 2010 to 168 in 2011 to 173 in 2012 with cases in Mexico going from 211 in 2010 up to 216 in 2011 and down to 215 in 2012. We asked Patrick’s campaign about Battleground Texas’s claim and the reports that Patrick described and didn’t hear back. Our ruling The Battleground Texas activist said Patrick has ""called immigration into Texas an invasion"" and Patrick has ""said immigrants coming into Texas bring ‘third-world diseases.’"" This year and earlier, Patrick referred to illegal immigration as an invasion that he wants to stopper. In 2006, he was quoted as saying illegal immigrants bring third-world diseases to the state. Both claims have weaknesses, but we're not judging Patrick's veracity here. The Democratic group's statement is . – The statement is accurate and there’s nothing significant missing." Claim: "Battleground Texas Says Dan Patrick has ""called immigration into Texas an invasion"" and ""said immigrants coming into Texas bring ‘third-world diseases.’"
[A]:
"The Battleground Texas activist said Patrick has ""called immigration into Texas an invasion"" and Patrick has ""said immigrants coming into Texas bring ‘third-world diseases.’"" This year and earlier, Patrick referred to illegal immigration as an invasion that he wants to stopper. In 2006, he was quoted as saying illegal immigrants bring third-world diseases to the state. Both claims have weaknesses, but we're not judging Patrick's veracity here. The Democratic group's statement is True. TRUE – The statement is accurate and there’s nothing significant missing."