Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Input: Consider Input: Paragraph: A nurse prepares a bottle of donated milk for a baby at Son Dureta's Hospital in Palma de Mallorca, Spain March 10, 2006. REUTERS/Dani Cardona The chemical bisphenol A, or BPA, is commonly used in plastic food and beverage containers and in the coating of food cans. Until now, environmental and consumer activists who have questioned the safety of BPA have relied on animal studies. But the study by British researchers in the Journal of the American Medical Association found that among 1,455 U.S. adults, those with the highest levels of BPA were more likely to have heart disease, diabetes and liver-enzyme abnormalities than those with the lowest levels. U.S. Food and Drug Administration officials said they would review the new findings, which were not yet published when the agency issued a draft conclusion in August that BPA is safe at current exposure levels. “We have confidence in the data that we’ve looked at and the data that we’re relying on to say that the margin of safety is adequate,” FDA official Laura Tarantino said at a meeting of experts advising the agency on whether it made the right call. “There are things you can do if you choose to reduce your level of bisphenol A,” Tarantino said. “But we have not recommended that anyone change their habits or change their use of any of these products because right now we don’t have the evidence in front of us to suggest that people need to.”   Panel chairman Martin Philbert declined to say what the committee’s next move would be. BPA is used to make polycarbonate plastic, a clear shatter-resistant material in products ranging from baby bottles to medical devices. BPA can mimic the hormone estrogen in the body. People can consume BPA when it leaches out of the plastic into baby formula, water or food inside a container. Some retailers and manufacturers are moving away from products with BPA. Canadian officials have concluded BPA was harmful. Steven Hentges of the American Chemistry Council, an industry group, said the study’s design did not allow for anyone to conclude BPA causes heart disease and diabetes. “On the other hand, though, bisphenol A has been very intensively studied in a very large number of laboratory animal studies. And the weight of evidence from those studies ... continues to support the safe use of products containing bisphenol A,” he said in a telephone interview. The British researchers, who acknowledged their findings are not proof that the chemical is causing the harm, analyzed urine samples from a U.S. government health survey of adults ages 18-74 representative of the U.S. population. The 25 percent of people with the highest levels of bisphenol A in their bodies were more than twice as likely to have heart disease, including heart attacks or type 2 diabetes, compared to the 25 percent with the lowest levels. At the FDA panel meeting, several scientists and activists said the FDA ignored animal studies finding health concerns and some called for the chemical to be banned in food containers. Democratic U.S. Rep. John Dingell of Michigan, who heads the House Committee on Energy and Commerce, said the FDA has “focused myopically on industry-funded research.”   Iowa Republican Sen. Chuck Grassley, ranking member of the Committee on Finance, released a letter he wrote to FDA Commissioner Dr. Andrew von Eschenbach asking why the agency has not appointed a safety panel to review BPA. Tarantino said nothing was ignored but industry-funded studies finding no harm were important in the conclusions. The panel is expected to present its advice to the FDA next month. Tarantino, head of the FDA’s office of food additive safety, said there is talk of government scientists doing their own BPA safety studies, but that could take years to conduct. Claim: Common plastics chemical linked to heart problems.

Output: A major study links a chemical widely used in plastic products, including baby bottles, to health problems in humans like heart disease and diabetes, but U.S. regulators said on Tuesday they still believe it is safe.


Input: Consider Input: Paragraph: "Atlanta Mayor Kasim Reed has made no secret of wanting to close the homeless shelter at Peachtree and Pine streets. Reed, who has been active in downtown’s post-Recession resurgence, says he’ll push for the city to acquire the property through eminent domain and turn it into a police precinct and fire station. Health concerns are a major reason for closing the Peachtree-Pines shelter, Reed said during a lunchtime speech to Atlanta’s Commerce Club on Tuesday, Aug. 11. ""Peachtree and Pine is one of the leading sites for tuberculosis in the nation,"" he told the crowd. Reed said top officials with the Centers for Disease Control and Prevention recently asked to meet with him and ""laid out how tuberculosis cases, not in Georgia, but across America, are being traced back to Peachtree and Pine."" Could Peachtree-Pine, billed as the largest homeless shelter in the Southeast, be a leading site for tuberculosis in the nation? PolitiFact decided to do some checking. First a little background. The homeless are prime candidates for tuberculosis because they typically have greater exposure to cold weather, are in crowded conditions when they stay in shelters and lack proper nutrition and medical care. That means shelters, such as Peachtree-Pine, have to be vigilant to avoid becoming breeding grounds for TB, which is spread person to person through the air and caused by the bacteria Mycobacterium tuberculosis. TB normally attacks the lungs, but also can strike the kidney, spine, brain or another body part. In most cases, tuberculosis is treatable and curable, although people can die if they don’t receive the proper treatment. Most people live with the bacteria, or latent TB infection, without feeling sick or showing symptoms. In 2014, 9,412 new tuberculosis cases were reported in the U.S., 334 in Georgia, according to the CDC. A new drug-resistant strain of TB was discovered in 2008 at the shelter at Peachtree and Pine, which is run by the Metro Atlanta Task Force for the Homeless. The strain was labeled G05625 TB by the CDC. The research To fact check Reed’s statement, we reached out to Fulton County government, the CDC, the mayor’s office and the Georgia Department of Public Health, as well as shelter management. Anita Beaty, Peachtree-Pine’s executive director, rejects Reed’s assessment of the shelter and says it is ""100 percent compliant"" with CDC protocol for spotting, treating and avoiding the spread of TB. She said Reed and the business community have conspired for years to force the shelter to close so they can take over its prime location, just south of Midtown and in sight of the Fox Theatre. Tuberculosis has been a worry at all Atlanta and Fulton County shelters, not just Peachtree-Pine, for years. But alarm bells apparently really started going off after an uptick in TB cases last year. ""At a time when the incidents of tuberculosis has been declining across the metropolitan Atlanta area and the rest of Georgia, it has actually increased in Fulton County,"" Brenda Fitzgerald, commissioner of the Georgia Department of Public Health, wrote Fulton County Commission Chair John Eaves in April. A month later, officials with the Centers for Disease Control and Prevention were sitting down for the first of two meetings with Reed about the ongoing TB problem generally, and Peachtree-Pine specifically. ""Our inability to control (the Peachtree-Pine) outbreak has led to infections in multiple other states,"" Philip A. LoBue and Jonathan Mermin, doctors with the National Center for HIV/AIDS, Viral Hepatitis, STD, and TB Prevention, wrote Reed after they met in May. Based on interviews, data and documents that PolitiFact reviewed, here’s a summary of the major points. -- Since 2008, new cases of the drug-resistant strain of TB that originated at the Peachtree-Pine shelter have turned up in metro Atlanta and Georgia as well as eight other states -- Alabama, California, Florida, Illinois, New York, North Carolina, Pennsylvania and South Carolina. (Genotype evidence, similar to a fingerprint, exists for every strain of TB, and that’s how every new case of G05625 in the state and nation can be traced to the Peachtree-Pine shelter. Similarly, that’s how the Ebola outbreak in west Africa in 201, was traced back to a 2-year-old from a small village in Guinea who died in 2013 and who became known around the world as Patient Zero.) -- At Fulton County’s four shelters, the number of TB cases rose by 230 percent, from 13 in 2013 to 43 in 2014. Twenty-two of the 43 cases, or slightly more than 50 percent, were at Peachtree-Pine. (The CDC defines a large outbreak as being 10 or more cases, CDC spokesman Brian Katzowitz said.) -- The number of drug-resistant G05625 tuberculosis cases, those linked to Peachtree-Pine, grew 10-fold from 2013 to 2014, from two to 23. -- Fulton County accounted for 82 percent of all cases of that strain of tuberculosis in Georgia and 69 percent of all cases of the strain in the United States. -- At least four clients of the Peachtree-Pine shelter, according to Fitzgerald, have died of tuberculosis since early 2014. In her letter to Eaves, Fitzgerald said, public health researchers identified the homeless shelter at the corner of Peachtree and Pine Streets ""as a major source of the current outbreak. ""If it [tuberculosis]  gains a foothold in the community, then the cost in healthcare and human suffering will be incalculable,"" she wrote. Jessica A. Corbitt-Dominguez, director of external affairs for Fulton County government, said Fulton health workers, in conjunction with officials from the Georgia Department of Public Health and CDC, responded to the outbreak with an aggressive campaign of education, testing and treatment. Anyone with active disease was relocated from the shelters while in treatment under the supervision of Fulton Health and Wellness. The county set up special teams that make daily visits to shelters to perform screenings and administer medicines, Corbitt-Dominguez said. In June 2015, the county health department also signed memorandums of understanding (MOUs) with four shelters, including Peachtree and Pine. This was considered a significant step since a lack of administrative controls and protocols is considered a likely contributor to the spread of TB. As of this month, the number of 2015 confirmed TB cases at Fulton homeless shelters is 13, Corbitt-Dominguez said. Beaty’s attorney last week provided reporters with a certificate showing the shelter is fully in compliance with the CDC’s TB protocol, and Beaty told PolitiFact ""it’s ludicrous to think we wouldn’t be on it."" Corbitt-Dominguez confirmed that the shelter has never been cited by the county, although Eaves has said there have been concerns about the shelter’s TB safeguards. In a letter to Fitzgerald, he wrote that the shelter’s administration ""routinely exhibits sub-optimal administration of the procedures required to control the spread of this disease."" Beaty said Reed’s statement makes clear he ""is just not getting good information."" ""We have been cleared by Fulton County, which is on site every day to monitor. And we’ve got 100 percent clearance from the CDC’s requirements,"" she said. ""We resent those easy headlines that have no basis in fact and that marginalize homeless people in our facilities."" Tom Andrews, president of the non-profit Mercy Care, which operates 14 clinics, some associated with shelters, said the strain of TB originating at Peachtree-Pine has to be a major concern. Since it is medicine-resistant, it requires a more expensive and longer treatment program, Andrews said. The CDC estimates that the costs of treating a person with TB increases with greater resistance. Direct costs in 2010 U.S. dollars average from $17,000 to treat drug-susceptible TB to $430,000 to treat the most drug-resistant form, according to the agency’s website. So is it a national leader in TB? We asked the mayor’s office for evidence to back up Reed’s statement that Peachtree-Pine ""is one of the leading sites for tuberculosis in the nation."" Anne Torres, his spokeswoman, provided us copies of the letters from Fitzgerald and the doctors, as well as a highly technical report from the CDC. We reached out to the CDC. A spokesperson said agency officials would not comment on the mayor’s public statements. CDC officials also would not identify the states where they said the TB strain from Peachtree-Pine had spread. We were able to obtain that list from the Georgia Department of Public Health, as well as the number of cases of G05625 strain TB in each state from 2008 to 2014. The most were in Florida (14), followed by California (8) and North Carolina and Alabama (2 each). New York, Illinois, Pennsylvania and South Carolina each reported one case in the five years -- for a total of 30 in the eight states in five years. But do 30 cases over a several-year period raise Peachtree-Pine to a leading site of TB in the nation? We posed that question to Philip Hopewell, a leading tuberculosis expert and professor of medicine at the University of California, San Francisco. ""Peachtree and Pine is clearly  a major site for transmission of Mycobacterium tuberculosis, and it may be one of the leading sites in the nation,"" Hopewell said. ""However, there are not data from every such facility in the country,"" he added. ""To say that the Atlanta facility is one of the leading sites in the country -- it probably is -- implies that there are data with which to compare the Atlanta facility. Thus, strictly speaking, what he said can't be backed with evidence. Even so, I wouldn't fault the mayor for saying this."" Our ruling Mayor Kasim Reed said ""Peachtree and Pine is one of the leading sites for tuberculosis in the nation."" Thirty cases of a medicine-resistant strain of TB in eight states have been traced back to the shelter at Peachtree and Pine. The shelter also had a large share of the cases in a recent TB outbreak in Fulton County and four TB deaths, according to state data. CDC officials clearly believe it’s a concern, but a leading tuberculosis expert says there’s a dearth of comparative data." Claim: Peachtree and Pine is one of the leading sites for tuberculosis in the nation.

Output: "Mayor Kasim Reed said ""Peachtree and Pine is one of the leading sites for tuberculosis in the nation."" Thirty cases of a medicine-resistant strain of TB in eight states have been traced back to the shelter at Peachtree and Pine. The shelter also had a large share of the cases in a recent TB outbreak in Fulton County and four TB deaths, according to state data. CDC officials clearly believe it’s a concern, but a leading tuberculosis expert says there’s a dearth of comparative data."


Input: Consider Input: Paragraph: A pharmacist in a file photo. The issue of prescription drug abuse shot to prominence with January's death of 28-year-old Hollywood actor Heath Ledger after he took six different prescriptions. REUTERS/File But that’s where her trouble with addiction began. By age 14, the teen from an upper middle-class Philadelphia suburb led a dangerous double life. Editor of her school paper, strong student and popular athlete, Roisman was also hooked on painkillers and other drugs in an addiction that illustrates the rapid expansion in prescription drug abuse in America. “My friends and I would take a bunch of different pills and break them up and put them all together and call it confetti. It could be any combination of anything. We could learn from it, and continue to take it,” said Roisman, who is now 17. The issue of prescription drug abuse shot to prominence with January’s death of 28-year-old Hollywood actor Heath Ledger after he took six different prescriptions. The death of Ledger, who plays the Joker in the new Batman film “The Dark Night,” adds to a growing list of prescription drug overdoses that includes Playboy model Anna Nicole Smith in 2007. Other deaths are less celebrated. In the 45-54 age group, overdose deaths fueled by prescription drugs now surpass motor vehicle deaths as the nation’s No. 1 cause of accidental death, federal data show. The federal data also show nearly 7 million Americans abused prescription drugs in 2007 — more than cocaine, heroin, hallucinogens, Ecstasy and inhalants such as marijuana combined. The figure is up 80 percent since 2000. Definitions of abuse vary but refer typically to nonmedical use of prescription drugs. The number of Americans treated for abuse of painkillers surged 321 percent from 1995 to 2005, federal statistics show — a trend some health experts link to another stunning figure: the 180 million prescriptions dispensed legally by U.S. pharmacies each year for pain medication. In Florida, whose reputation for cocaine and other hard drugs was burnished in movies such as “Scarface” and “Miami Vice,” the rate of deaths caused by prescription drugs was three times the rate of death caused by all illicit drugs combined, according to an analysis of 2007 autopsies by the Florida Medical Examiners Commission released in June. “What you have among over the counter and prescription drug use is a very low perception of risk,” said Stephen Pasierb, president and chief executive of the Partnership for a Drug-Free America, a nonprofit advocacy group. “There’s very low social disapproval. In fact, there are parents who almost relieved that their kid is using Vicodin and not smoking marijuana,” he said. Len Paulozzi, an epidemiologist with the National Center for Injury Prevention and Control, testified recently in Congress that he believed physicians were improperly trained in the long-term dangers of therapy involving opioid painkillers, or drugs containing opium. “There are guidelines out there, but we don’t think that they’re being routinely followed,” he said. Sen. Joseph Biden, a Democrat from Delaware, proposed to make August 2008 “National Medicine Abuse Awareness Month” in a resolution now before the Senate Judiciary Committee, saying the Internet had become “an information superhighway” for abuse of medicine in the United States. But containing the abuse is notoriously difficult. Thirty-eight states have passed legislation for prescription drug monitoring programs to trace the source of drugs, and police in some states have had success in reducing pharmacy break-ins. A University of Maine program provides pre-addressed, postage-paid pouches to the elderly so they can mail their surplus prescription drugs to state authorities for disposal in a bid to reduce the amount that get into the wrong hands. None of the measures has stopped the growth nationwide, and experts point to several stubborn problems, including the phenomenon of “doctor shopping,” in which patients go to multiple doctors to get several prescriptions. Hundreds of online pharmacies also offer drugs that include generic versions of opiates like Purdue Pharma’s OxyContin, methadone and Abbott Laboratories Inc’s Vicodin, which are legitimately prescribed as painkillers, along with stimulants like Ritalin made by Novartis, and benzodiazepines like Pfizer’s Xanax. It is as easy in the United States to buy opiates or other abusable prescription drugs online as it is to purchase a book, said David Festinger, a scientist who has studied online drug sales at the Treatment Research Institute at the University of Pennsylvania. Regulating such trade is tough, he said. “These Internet enterprises set up a bank account in one country, buy their drugs from another country, and do their merchandising and sales from another country,” he said. “Everything is spread all over the globe. And in an instant, if anybody’s on their tail, they can switch everything around.”   For many children, getting the drugs is simple. In Philadelphia, Roisman and her friends raided family medicine cabinets for the big prizes — OxyContin, a kind of synthetic morphine also known as “hillbilly heroin,” along with Ritalin and Vicodin — until she eventually passed out one day in school. A drug test showed she had seven drugs in her system. “People think that it’s OK because it’s a prescribed pill. It comes from a credible source. Even if a doctor has not told you it’s OK, they’ve told someone else it’s OK,” said Roisman, who became sober two years ago after treatment at a rehab center run by the nonprofit Caron organization. She blames doctors for failing to “watch what they are prescribing” and parents for failing to understand “just how hard people will work to get what they want when they are an addict,” adding many teens use the drugs to help study. On college campuses, popping Adderall, Ritalin and other prescribed amphetamine-like psychostimulant drugs is a popular way to help cram for tests and cope with academic pressure. Some are legitimately prescribed for Attention Deficit Hyperactivity Disorder, helping sufferers increase alertness, attention and energy. But many use it without prescriptions. Almost 60 percent of students have been offered an opportunity to try prescription stimulants by their junior (third) year of college in the United States, said Amelia Arria, a senior researcher at the University of Maryland’s Center for Drug Abuse Research, which surveyed 1,253 students on drug usage. Health insurers are also feeling the effects. Some face mounting pressure to expand coverage to include substance-abuse disorders. Others are grappling with swindlers who obtain illicit prescription narcotics through fraudulent insurance claims for bogus prescriptions, treating phantom injuries. Such fraud costs health insurers up to $72.5 billion (36.6 billion pounds) a year, according to a 2008 report by the Coalition Against Insurance Fraud, an advocacy group based in Washington. Claim: U.S grapples with rising prescription drug addiction.


Output: When Sarah Roisman was 11 years old, her doctors prescribed Klonopin, a muscle relaxant, for a psychiatric disorder that caused her to have seizures. She liked how the drug made her feel. Her seizures went away.