instruction:
This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.
question:
On 25 May 1963, the pope suffered another haemorrhage and required several blood transfusions, but the cancer had perforated the stomach wall and peritonitis soon set in. The doctors conferred in a decision regarding this matter and John XXIII's aide Loris F. Capovilla broke the news to him saying that the cancer had done its work and nothing could be done for him. Around this time, his remaining siblings arrived to be with him. By 31 May, it had become clear that the cancer had overcome the resistance of John XXIII – it had left him confined to his bed.
answer:
What did the pope suffer on 25 May 1963?


question:
In 1868, the horse-drawn tram company Compañía de Tranvías al Paso del Molino y Cerro created the first lines connecting Montevideo with Unión, the beach resort of Capurro and the industrialized and economically independent Villa del Cerro, at the time called Cosmopolis. In the same year, the Mercado del Puerto was inaugurated. In 1869, the first railway line of the company Ferrocarril Central del Uruguay was inaugurated connecting Bella Vista with the town of Las Piedras. During the same year and the next, the neighbourhoods Colón, Nuevo París and La Comercial were founded. The famous to our days Sunday market of Tristán Narvaja Street was established in Cordón in 1870. Public water supply was established in 1871. In 1878, Bulevar Circunvalación was constructed, a boulevard starting from Punta Carretas, going up to the north end of the city and then turning west to end at the beach of Capurro. It was renamed to Artigas Boulevard (its current name) in 1885. By Decree, on 8 January 1881, the area Los Pocitos was incorporated to the Novísima Ciudad (Most New City).
answer:
What year did Compania de Tranvias al Paso del Molino y Cerro creat the first lines connecting Montevideo with Union?


question:
Southampton as a Port and city has had a long history of administrative independence of the surrounding County; as far back as the reign of King John the town and its port were removed from the writ of the King's Sheriff in Hampshire and the rights of custom and toll were granted by the King to the burgesses of Southampton over the port of Southampton and the Port of Portsmouth; this tax farm was granted for an annual fee of £200 in the charter dated at Orival on 29 June 1199. The definition of the port of Southampton was apparently broader than today and embraced all of the area between Lymington and Langstone. The corporation had resident representatives in Newport, Lymington and Portsmouth. By a charter of Henry VI, granted on 9 March 1446/7 (25+26 Hen. VI, m. 32), the mayor, bailiffs and burgesses of the towns and ports of Southampton and Portsmouth became a County incorporate and separate from Hampshire.
answer:

Southampton's history of administrative independence dates back to the reign of which king?