In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
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Question: Paragraph: The outbreak of a new coronavirus (SARS-CoV-2) disease has become pandemic. To be more effectively controlling the disease, it is critical to set up an optimal quarantine period so that about 95% of the cases developing symptoms will be retained for isolation. At the moment, the WHO-established quarantine period is 14 days based on previous reports which had studied small sizes of hospitalized cases (10 and ~100, respectively), however, over 80% of adult-and 95% of child-cases were not necessary to stay in hospitals, and therefore, had not been hospitalized. Therefore, we are questioning if the current-inferred median incubation time is representative for the whole Covid-19 population, and if the current quarantine period is optimal. We compiled and analyzed the patient-level information of 2015 laboratory-confirmed Covid-19 cases including 99 children in 28 Chinese provinces. This cohort represents a wide-range spectrum of Covid-19 disease with both hospitalized and non-hospitalized cases. The full range of incubation periods of the Covid-19 cases ranged from 0 to 33 days among 2015 cases. There were 6 (0.13%) symptom-free cases including 4 females with a median age of 25.5 years and 2 males with a median age of 36 years. The median incubation period of both male and female adults was similar (7-day) but significantly shorter than that (9-day) of child cases (P=0.02). This cohort contained 4 transmission generations, and incubation periods of the cases between generations were not significantly different, suggesting that the virus has not been rapidly adapted to human beings. Interestingly, incubation periods of 233 cases (11.6%) were longer than the WHO-established quarantine period (14 days). Data modeling suggested that if adults take an extra 4-day or 7-day of isolation (i.e., a quarantine period of 18 or 21 days), 96.2% or 98.3%, respectively, of the people who are developing symptoms will be more effectively quarantined. Patients transmitted via lunch/dinner parties (i.e., gastrointestinal tract infection . CC-BY-NC 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity. is the (which was not peer-reviewed) The copyright holder for this preprint . 
 Title: Is a 14-day quarantine period optimal for effectively controlling coronavirus disease 2019 (COVID-19)?

Answer: False


Question: Paragraph: Biological oscillators are vital to living organisms, which use them as clocks for time-sensitive processes. However, much is unknown about mechanisms which can give rise to coherent oscillatory behavior, with few exceptions (e.g., explicitly delayed self-repressors and simple models of specific organisms' circadian clocks). We present what may be the simplest possible reliable gene network oscillator, a self-repressing gene. We show that binding cooperativity, which has not been considered in detail in this context, can combine with small numbers of intermediate steps to create coherent oscillation. We also note that noise blurs the line between oscillatory and non-oscillatory behavior. 
 Title: Oscillation, cooperativity, and intermediates in the self-repressing gene

Answer: True


Question: Paragraph: Since the 1980s the epidemiology of Clostridium difficile infection (CDI) has been investigated by the application of many different typing or fingerprinting methods. To study the epidemiology of CDI, a typing method with a high discriminatory power, typeability, stability, power, reproducibility and epidemiological concordance is required. It should also have technical advantages, such as ease of performance, relative low cost, and high throughput. A growing number of molecular methods have been applied to C. difficile. For the early and rapid detection of outbreak situations, methods such as restriction enzyme analysis, arbitrary primed polymerase chain reaction (PCR), pulsed-field gel electrophoresis, and PCR ribotyping are commonly used. For long-term epidemiology, multilocus sequence typing, multilocus variable number of tandem repeats analysis (MLVA), and amplified fragment length polymorphism are of interest. Currently, the PCR-ribotyping method and the library of PCR ribotypes in Cardiff are the benchmarks to which most typing studies around the world are compared. Conventional agarose gel-based PCR ribotyping is easy to use and relatively cheap, but analysis of fragment lengths is hampered by poor resolution. Recently, a capillary gel electrophoresisbased PCR ribotyping assay has been developed that significantly reduces the hands-on time required for C. difficile PCR ribotyping. The results were highly reproducible, independent of reagent batches or brands used and allows inter-laboratory comparisons of typing results. The analysis of the sequenced C. difficile genome revealed a high percentage of DNA that consisted of a variable number of tandem repeats (VNTR). Recently, a new MLVA method was developed using smal short tandem repeats (2−9 bp) to facilitate automated fragment analysis with multicoloured capillary electrophoresis instead of sequencing. In a study using isolates from laboratories in Canada, the Netherlands, the United Kingdom, and the United States, seven C. difficile typing techniques were compared, but only REA and MLVA showed sufficient discrimination to distinguish strains from different outbreaks. MLVA has also been applied to study local outbreaks of C. difficile PCR ribotype 027 strains. MLVA is currently the most discriminative typing method and will contribute significantly to our understanding of the epidemiology of C. difficile. S3 New treatment aspects of CDI The need for new therapeutic alternatives in CDI is clear. Current recurrence rates are unacceptably high. The optimal treatment of severe CDI, infection caused by strains associated with poor outcome (e.g. C. difficile ribotype 027), and multiple recurrences is unclear. There are several potentially promising new CDI treatment approaches under investigation, including antibiotic, anti-toxin and bacterial interference options. Probiotic therapy remains of unproven benefit. As new options become available, prognostic data will be needed to guide on the most approriate therapeutic choices. 
 Title: Oral presentations New aspects of emerging Clostridium difficile infections (CDI) S2 Pros and cons of molecular fingerprinting for Clostridium difficile infections

Answer:
False