Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Input: Consider Input: Malaria, which is the result of Plasmodium falciparum infection, is a global health threat that resulted in 655,000 deaths and 216 million clinical cases in 2010 alone. Recent phase 3 trials with malaria vaccine candidate RTS,S/AS01 (RTS,S) in children has demonstrated modest efficacy against clinical and severe malaria. RTS,S targets the pre-erythrocytic phase of the disease and induces high antibody titers against the P. falciparum circumsporozoite protein (CSP) and a moderate CD4(+) T cell response. The individual contribution of these adaptive immune responses to protection from infection remains unknown. Here, we found that prophylactic administration of anti-CSP mAbs derived from an RTS,S-vaccinated recipient fully protected mice with humanized livers from i.v.- and mosquito bitedelivered P. falciparum sporozoite challenge. Titers of anti-CSP that conveyed full protection were within the range observed in human RTS,S vaccine recipients. Increasing anti-CSP titers resulted in a dose-dependent reduction of the liver parasite burden. These data indicate that RTS,S-induced antibodies are protective and provide sterilizing immunity against P. falciparum infection when reaching or exceeding a critical plasma concentration.

Output: RTS S AS01 vaccine was developed to prevent which disease?


Input: Consider Input: Jonas Valanciunas (Lithuanian pronunciation: (jons vntuns); born 6 May 1992) is a Lithuanian professional basketball player for the Toronto Raptors of the National Basketball Association (NBA).

Output: What team is Jonas Valančiūnas on?


Input: Consider Input: Get Water! is a mobile game about the water scarcity in India and South Asia, and the effects it has on girls' education.


Output: Which place is Get Water! in?