Given a document, generate a short title of the document. The title should convey the main idea/event/topic about which the document is being written. Note that URLs in the text have been replaced with [Link].

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A few years ago he began working with Dr. Jenny Chang  medical director of the Lester and Sue Smith Breast Center at Baylor College of Medicine.
 Chang had performed a number of biopsies on breast cancer patients  both on those whose cancers were confined to the breast and on those whose cancers had metastasized to the brain.
 From those biopsies  Chang said she had identified a number of genetic pathways ways in which gene mutations affected the ability of the cancer to spread unique to patients who developed metastatic breast cancer.
 "But I had a lot of trouble with the data and trying to translate it into clinical practice " she said. She couldn't find her way out from beneath the avalanche of data.
 So she turned to Wong.
 Using his mathematical modeling  Wong sifted through Chang's data and the large databases of genome and clinical trial data. Out of that  he identified several candidate drugs to impair the genetic pathways that helped the cancer spread.
Chang's data and the large databases of genome and clinical trial data. Out of that  he identified several candidate drugs to impair the genetic pathways that helped the cancer spread.
 One of them  a drug named sunitinib  which treats a kidney cancer called renal cell carcinoma  emerged as the best bet. Chang then tested the drug in mice  and the study showed it prevented breast cancer from spreading to the brain.
 She has already begun a Phase II clinical trial of the drug  enrolling nine patients with metastatic breast cancer  and she is looking for more.
 "The drug is very well-tolerated by patients  and so far the trial is going very well " Chang said.
 But by using an existing drug  Chang and Wong could skip the lengthy Phase I  during which a drug is checked for safety. If Chang's tests go well  sunitinib could be on the market within a few years for metastatic breast cancer.

Ex Output:
IN OLD DRUGS RESEARCHER LOOKS FOR NEW TREATMENTS


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MANILA  Philippines -- Human rights groups condemned  the Philippine president  on Tuesday for saying that troops should shoot female communist rebels in the genitals to render them "useless " which they said could encourage sexual violence and war crimes. The left-wing group Karapatan said  President Rodrigo Duterte  "has distinguished himself as a frothing-in-the-mouth fascist who incites the worst violations of international humanitarian law."
 Duterte 's remarks "are but the latest of the series of this madman's display of tyranny  lunacy and machismo " Karapatan Secretary General Cristina Palabay said.
In a rambling speech before surrendered communist rebels   Duterte  spoke about the futility of their decades-old insurgency and how  his  administration can help them return to normal life.
 Duterte  asked why even women join the insurgency and abandon their families.
At one point   he  said without elaborating: "Tell the soldiers. There's a new order coming from the mayor. We won't kill you. We will just shoot your vagina so that ... if there is no vagina  it would be useless."
 Duterte  spoke in the Bisaya dialect. An official transcript of the president's speech issued by the government omitted the word "vagina" and expletives from his remarks.
A longtime mayor of southern Davao city  where he built a reputation for his extra-tough approach to criminality and his brash  often sex-laden remarks   Duterte  has acknowledged  his  rough ways but suggested many Filipinos have come to accept  him .
Western governments and human rights watchdogs have expressed alarm over  his  crackdown on illegal drugs  which has left thousands of mostly poor suspects dead.  He  has lashed out at critics  including European governments  which  he  told Monday "to go to hell" for imposing conditions on financial aid.
 Duterte  said  he  has told European officials  he  won't attend an upcoming meeting between Southeast Asian and European leaders.
"They say that I have a bad mouth. It's true. They say that I'm not a statesman  not fit for a president  and that's true  " Duterte  said in a speech Monday  referring to  his  critics. "But the problem here is that I won."
Steve Rood  a Manila-based political analyst  said many Filipinos like  Duterte 's unorthodox style and his charm when he talks to them in an intimate way  as if his speeches were not being broadcast.
With crime easing and recent public surveys showing satisfaction with  Duterte 's administration  the president's opponents may do better if they focus on issues such as traffic jams in the capital and rising rice prices  he said.

Ex Output:
Philippine President Rodrigo Duterte slammed over threat to shoot rebels in the genitals


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Ellen Tara James-Penney  a lecturer at San Jose State University   has been sleeping out of a car for about a decade  ever since  she  lost  her  housing while an undergraduate at the school where  she  now teaches four English courses  a job that pays $28 000 a year. Home is an old Volvo.
"I've basically been homeless since 2007  and I'm really tired "  she  said. "Really tired."
 She  actually got  her  start in the high tech industry  before being laid off during the tech meltdown of the early 2000s. Like many who couldn't find work   she  went to college  accumulating tens of thousands of dollars in student debt along the way.
Now 54   she  grades papers and prepares lesson plans in  her  car. Among  her  few belongings is a pair of  her  grandmother's fancy stiletto pumps  a reminder to  herself  that "it's not going to be like this forever."
For Seattle resident Elisabeth James  the reality check came when a homeless man forced his way into a glass-enclosed ATM lobby with her after she swiped her card to open the door for after-hours access. After a few nerve-wracking minutes  the man left the lobby but stayed outside  banging on the glass. Police were too busy to respond so  James  called  her  husband  who scared the man away and walked  her  home. The man   she  believes  just wanted to get out of the rain.
A neighborhood pocket park has become a flashpoint  too: When  James  took  her  2-year-old grandchild there   she  saw people injecting heroin.

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Amid booming economy homelessness soars on US West Coast