Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: Successful treatment with partial resection of the posterior mitral valve leaflet and antibiotic therapy with cefazolin.

Output: non-adverse drug event


Input: Consider Input: CONCLUSIONS: The results of our study suggest that the pharmacokinetics of parent ifosfamide may not be substantially altered in patients with renal failure.

Output: non-adverse drug event


Input: Consider Input: We report a case of 48-year-old woman with seizure disorder on divalproex sodium (Depakote) who presented with dyspnea.


Output: adverse drug event