Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Q: Context: The Narym River is a river in the Eastern Kazakhstan, a tributary of the Irtysh River, originating at the junction of the ridges Narym and Sarymsakty of wetland formed by the mountain runoff streams. 
 Question: The body of water that Narym River is near is what?

A: irtysh river
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Q: Context: Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, demonstrated efficacy and safety in moderate-to-severe plaque psoriasis when administered via subcutaneous injection. Self-administration by pre-filled syringe (PFS) can offer patients clinical benefits of a drug, with increased convenience. To assess efficacy, safety and usability of secukinumab administration via PFS in subjects with moderate-to-severe plaque psoriasis. Subjects in this phase 3 trial were randomized 1:1:1 to secukinumab 300 or 150mg or matching placebo. Results to week 12 are presented here. Each treatment was delivered using a PFS once weekly to week 4, and again at week 8. Co-primary endpoints were secukinumab superiority over placebo for week 12 PASI 75 (75% reduction in Psoriasis Area and Severity Index) and IGA mod 2011 (2011 modified Investigator's Global Assessment) 0/1 response rates. Secondary endpoints included PFS usability, determined by observer rating of successful, hazard-free self-injection and subject rating of acceptability by the Self-Injection Assessment Questionnaire (SIAQ). Co-primary endpoints were met, with demonstration of superiority for each secukinumab dose vs. placebo at week 12 (PASI 75: 759%, 695% and 0% for secukinumab 300mg, 150mg and placebo; IGA mod 2011 0/1: 690%, 525% and 0%, respectively; P<00001 for all comparisons vs. placebo). PFS usability was high: 100% of subjects successfully self-administered treatment at week 1, and subjects reported high SIAQ-assessed acceptability of the PFS throughout the trial. No new/unexpected safety signals were observed. Secukinumab administration by PFS was effective, with an acceptable safety profile and high usability. The PFS provides a reliable, convenient form of secukinumab administration in subjects with moderate-to-severe plaque psoriasis. 
 Question: Which molecule is targeted by a monoclonal antibody Secukinumab?

A: interleukin-17a
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Q: Context: Queen of the Summer Stars is a 1991 novel by Persia Woolley and is the second volume of the Guinevere trilogy that relate the Arthurian legend from the perspective of Guinevere. 
 Question: What is the series that Queen of the Summer Stars is a part of?

A:
guinevere trilogy
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