Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
We describe the development of severe lipoatrophy in a patient treated with biphasic aspart.

Ex Output:
non-adverse drug event


Ex Input:
Scans were performed without opioid drugs and 30 minutes after intramuscularly administered meperidine, morphine, hydroxyzine, hydroxyzine plus meperidine, butorphanol, and nalbuphine.

Ex Output:
non-adverse drug event


Ex Input:
One patient received moxalactam as part of the combination therapy for diffuse pulmonary infiltration during renal transplant rejection.

Ex Output:

non-adverse drug event