instruction:
In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
question:
 High constitutive expression of the IFNgamma - inducible genes , IFN - stimulated gene factor 3 gamma subunit ( ISGF3gamma ) , IFN regulatory factor - 1 ( IRF - 1 ) , and the cyclin - dependent kinase inhibitor p21 ( WAF1 ) was found in FANCC mutant B lymphoblasts , low - density bone marrow cells , and murine embryonic fibroblasts .
answer:
IRF - 1


question:
 Interestingly , addition of PGF ( 2alpha ) , which was not known to affect lymphocytes , dramatically attenuated the deleterious effects of PPAR - gamma agonists on B lymphomas .
answer:
PPAR - gamma


question:
 It induced NK cell - dependent rejection of tumors , but failed to stimulate systemic T cell - mediated anti - tumor immunity , and synergized with B7 - 1 - mediated immunotherapy to cause the NK cell and CD8 T cell - dependent rejection of larger EL - 4 tumors ( 0 . 4 cm in diameter ) that were refractory to monotherapies .
answer:

B7 - 1