Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

[EX Q]: Question: Does hypoxia interfere with connective tissue growth factor ( CTGF ) gene expression in human proximal tubular cell lines?
Answer: We provide evidence that hypoxia inhibits CTGF synthesis in human proximal tubular epithelial cells, involving HIF-1alpha. Under hypoxic conditions, induction of CTGF by TGF-beta was repressed. The reduced synthesis of the profibrotic factor CTGF may contribute to a potential protective effect of hypoxic preconditioning in acute renal injury.
[EX A]: yes

[EX Q]: Question: Does restrictive left ventricular filling pattern result from increased left atrial pressure alone?
Answer: The restrictive filling pattern is distinguished from overfilling of a normal ventricle by a reduced and delayed E' and a shortened E deceleration time that reflect slow relaxation and increased LV stiffness.
[EX A]: no

[EX Q]: Question: Is early-onset Crohn 's disease a risk factor for smaller final height?
Answer: Prepubertal onset of CD is a risk for lower final height, independent of the initial disease location and the necessity for surgical interventions.
[EX A]:
yes