Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
Isoniazid causing breast tissue enlargement has been very rarely reported.

Ex Output:
adverse drug event


Ex Input:
After development of the tics in 2, CBZ was continued at the same or higher dose, and the tics abated and then ceased spontaneously < or = 6 months.

Ex Output:
non-adverse drug event


Ex Input:
Methicillin-resistant Staphylococcus aureus osteomyelitis of the scaphoid from a catheter in the radial artery.

Ex Output:

non-adverse drug event