This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

[Q]: London i/ˈlʌndən/ is the capital and most populous city of England and the United Kingdom. Standing on the River Thames in the south eastern part of the island of Great Britain, London has been a major settlement for two millennia. It was founded by the Romans, who named it Londinium. London's ancient core, the City of London, largely retains its 1.12-square-mile (2.9 km2) medieval boundaries and in 2011 had a resident population of 7,375, making it the smallest city in England. Since at least the 19th century, the term London has also referred to the metropolis developed around this core. The bulk of this conurbation forms Greater London,[note 1] a region of England governed by the Mayor of London and the London Assembly.[note 2] The conurbation also covers two English counties: the small district of the City of London and the county of Greater London. The latter constitutes the vast majority of London, though historically it was split between Middlesex (a now abolished county), Essex, Surrey, Kent and Hertfordshire.
[A]: What city is the capital of England?


[Q]: Serotonin is a neuromodulator involved in regulation of mood and behavior. Development in the limbic system plays an important role in determining rewards and punishments and processing emotional experience and social information. Changes in the levels of the neurotransmitters dopamine and serotonin in the limbic system make adolescents more emotional and more responsive to rewards and stress. The corresponding increase in emotional variability also can increase adolescents' vulnerability. The effect of serotonin is not limited to the limbic system: Several serotonin receptors have their gene expression change dramatically during adolescence, particularly in the human frontal and prefrontal cortex .
[A]: Which neuromodulator is involved in regulation of mood and behavior?


[Q]: Title IV of the 1978 Spanish constitution invests the Consentimiento Real (Royal Assent) and promulgation (publication) of laws with the monarch of Spain, while Title III, The Cortes Generales, Chapter 2, Drafting of Bills, outlines the method by which bills are passed. According to Article 91, within fifteen days of passage of a bill by the Cortes Generales, the sovereign shall give his or her assent and publish the new law. Article 92 invests the monarch with the right to call for a referendum, on the advice of the president of the government (commonly referred to in English as the prime minister) and the authorisation of the cortes.
[A]:
Which article in the Spanish constitution gives the monarch the right to ask for a referendum?