Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Q: Aava Whistler Hotel Star Ratings: Location: Whistler Rooms:192 Stay at the Aava Whistler Hotel (formerly Coast Whistler Hotel) and experience a great vacation. The Aava Whistler Hotel is within minutes from over a hundred shopping malls and restaurants. It also has a great number of recreational facilities, including swimming, diving and even skiing. Hotel services include 24-hour reception, laundry and room service. Guests can stay in cozy rooms equipped with air-conditioning, bathroom and television. From CNY=496 per night. Best Western Cairn Croft Hotel Star Ratings: Location: East Lundy's Lane Room:l66 Relax and unwind at the Best Western Cairn Hotel. This resort-style hotel is located just minutes from the airport. At the Best Western Cairn Croft, guests can enjoy a large number of recreational facilities, including children's activities, sightseeing and a swimming pool. Business travelers can also take advantage of spacious meeting and banqueting facilities for hosting corporate events. All rooms come with basic amenities . From CNY=439 per night. Clarion Hotel&Suites Downtown Montreal Star Ratings: Location:Montreal Rooms:266 Conveniently located just 20 minutes from the airport, the Clarion Hotel&Suite Downtown Montreal is a moderately-priced three-star hotel that provides services to both business and leisure travelers. The Clarion has spacious meeting facilities and modern business centers for business travelers. It also has a sauna and whirlpool where guest can relax. All rooms come with basic amenities, including cable TV and a kitchenette. From CNY=553 per night. Delta Bow Valley Hotel Star Ratings: Location:Calgary Rooms:398 The Delta Bow Valley Hotel is located a couple of blocks north of Olympic Plaza, east of James Short Park, and north-east of the Petro-Canada Centre. Apart from business and recreational services such as a business centre, fitness centre and restaurant, all rooms in the Delta come with a mini-bar and in-house movies. From CNY=l, 227 per night.

A: Which hotel offers facilities for children's activities?
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Q: Weathering is the process that changes solid rock into sediments. Sediments were described in the chapter "Ma- terials of Earths Crust." With weathering, rock is disintegrated. It breaks into pieces. Once these sediments are separated from the rocks, erosion is the process that moves the sediments. While plate tectonics forces work to build huge mountains and other landscapes, the forces of weathering gradually wear those rocks and landscapes away. Together with erosion, tall mountains turn into hills and even plains. The Appalachian Mountains along the east coast of North America were once as tall as the Himalayas. No human being can watch for millions of years as mountains are built, nor can anyone watch as those same mountains gradually are worn away. But imagine a new sidewalk or road. The new road is smooth and even. Over hundreds of years, it will completely disappear, but what happens over one year? What changes would you see? (Figure 1.1). What forces of weathering wear down that road, or rocks or mountains over time? A once smooth road surface has cracks and fractures, plus a large pothole. Click image to the left or use the URL below. URL:

A: the process that changes solid rock into sediments.
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Q: Hepcidin, a 25-amino-acid peptide secreted by the liver, distributed in the plasma and excreted in urine, is a key central regulator of body iron homeostasis. This hormone decreases export of cellular iron by binding to ferroportin, an iron exporter present at the basolateral surface of enterocytes and macrophages (the sites of dietary iron absorption and iron recycling, respectively), inducing its internalization and degradation. Hepcidin contains eight cysteine residues that form four disulfide bridges, which stabilize a hairpin-shaped structure with two beta sheets. We noticed in the sequence of hepcidin a Cys*-X-Cys* motif which can act as a metal binding site able to trap iron and/or copper. We have tested this hypothesis using a pseudopeptidic synthetic bis-disulfide analogue and we have shown that direct metalation of such ligand leads to the formation of a copper(III) complex with the typical N(2)S(2)donor set. This compound crystallizes in the orthorhombic system, space group Imma. The Cu(III) configuration is square planar, built up from two carboximado-N and two thiolato-S donors. This complex is converted back to the bis-disulfide, with release of the copper salt, upon oxidation with iodine.

A:
How many disulfide bridges has the protein hepcidin got?
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