In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Input: Consider Input: Question: The proteasome: 
 Options:  <1> It is formed by 21 homologous subunits organized in 3 rings. <2> It is a protein complex that catalyzes the hydrolysis of ubiquitinated proteins. <3> It is found only in animal eukaryotic cells. <4> Digest acylated proteins. <5> It is activated by a drug, bertezomil, in therapy for multiple myeloma.

Output: 2


Input: Consider Input: Question: African trypanosomes (T. Rhodesiense and T. Gambiense) are transmitted by insects of the genus: 
 Options:  <1> Glossina <2> Triatoma. <3> Panstrongylus. <4> Rhodnius. <5> Phlebotomus.

Output: 1


Input: Consider Input: Question: It does NOT occur during apoptosis: 
 Options:  <1> Rupture of the plasma membrane. <2> Condensation of chromatin. <3> Collapse of the cytoskeleton. <4> Fragmentation of DNA <5> Formation of apoptotic bodies.


Output: 1