Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

[Q]: Paragraph: The company said the trial will continue unchanged as per the recommendation of a data monitoring committee. The trial was testing Bristol-Myers’ drugs Opdivo and Yervoy, against Opdivo alone, in patients with advanced melanoma. The combination failed to show a statistically significant benefit in patients whose tumors had 1% or lower levels of the PD-L1 protein being targeted, the company said. The American Cancer Society estimates that about 96,480 melanoma cases will be diagnosed in the United States this year. Bristol-Myers shares were trading at $55.99 before the bell. Claim: Bristol-Myers misses main goal of late-stage skin cancer trial.
[A]: Bristol-Myers Squibb Co said on Wednesday a late-stage trial testing a combination of its cancer drugs missed a main goal of preventing skin cancer from recurring in a certain group of patients, sending its shares down nearly 1%.


[Q]: Paragraph: Since Nov. 1, South Carolina has recorded 86 reported cases of the contagious disease. State Epidemiologist Linda Bell said Monday that’s more than four times what state officials normally expect to see. Over the last 10 years, South Carolina averaged 19 reported cases of hepatitis A annually. Most of the new cases have occurred in Aiken County, and almost half of all cases involve individuals who reported drug use, Bell said. Still, the general population needn’t be overly concerned, she said. “But we are seeing cases higher that what we expect to see,” Bell said. “And so it’s important for us to do our prevention efforts early to reach those high-risk groups, get them vaccinated ... so that we can prevent” a severe outbreak. The State reports the Department of Health and Environmental Control is offering no-cost vaccines to high risk groups including drug users, homeless, formerly incarcerated and sexually-active gay men. Additionally, health officials recommend all children get two doses of the vaccine as part of their immunization schedule. Of the 86 reported cases in South Carolina, 59 have led to hospitalization and one resulted in death, the DHEC said. Hepatitis is a disease characterized by inflammation of the liver. It comes in many forms, including hepatitis A, B and C. As a result, individuals with chronic liver disease, like cirrhosis, are at increased risk of complications if infected and should be vaccinated. The virus-borne infection can be prevented by vaccination and is usually transmitted person-to-person through consumption of contaminated food or water, according to the U.S. Centers for Disease Control and Prevention. Antibodies produced in response to hepatitis A infection last for life and protect against reinfection. Infection usually results in sickness in two to six weeks after exposure. Symptoms include fatigue, loss of appetite, stomach pain, nausea, and yellowing of the eyes and skin. Symptoms usually resolve within two months of infection, according to the CDC. State public health officials in February declared an outbreak in Aiken County after an employee at a second restaurant in Aiken tested positive for the virus, the DHEC said. Bell, though, stressed transmission by food or beverage is uncommon. “Most transmission in the United States is through person-to-person contact,” Bell said. “Good hygiene - diligently washing your hands - is a good way to prevent hepatitis A, as well as not sharing personal items,” including drug equipment, she said, adding the state has received reports of hepatitis A from people using various drugs, “everything from marijuana to meth.” Residents can schedule an appointment for a vaccination at their local health department by calling 855-472-3432 or going to http://bit.ly/2HhEsM8 . ___ Information from: The State, http://www.thestate.com Claim: South Carolina declares hepatitis outbreak.
[A]: What began as a spike in reported hepatitis A cases in Aiken County has now spread to other parts of South Carolina, prompting public health officials to declare a statewide outbreak.


[Q]: Paragraph: Doctors’ letters provided to The Associated Press give glowing medical marks to both men. The AP requested the results of a post-primary physical and, for each, a list of any major health conditions or prescription medications. Neither has any medical problems to speak of. The two have been engaged in one of the year’s most expensive and closely watched Senate contests — though outside groups on both sides have begun pulling money from the race as Strickland fails to gain traction against Portman’s well-funded effort. The 60-year-old Portman, the Republican incumbent, is an avid sportsman who kayaks and cycles. He’s on no medications and has no illnesses or chronic conditions. Strickland, Ohio’s Democratic former governor, takes blood-pressure medicine. His doctor reports the 75-year-old has no illnesses or chronic conditions. Strickland would be the oldest person elected to a first term in the Senate — though he’d be far from the oldest in the chamber. Thirteen sitting senators are 75 or older. That includes eight who are 80 and above. The median age in the Senate is around 63. When questioned about his age, Strickland says longevity runs in his family. The Portman campaign provided a letter from the senator’s longtime doctor, James Hochwalt in Cincinnati, drawn from a July physical. “To my knowledge, there is nothing in his medical history or current medical status that would interfere with his demanding schedule and commitments of United States Senator,” Hochwalt wrote. Strickland’s physician, Paul Dusseau in Hilliard, also saw the candidate in July. In addition to an exam and lab work, Dusseau wrote that he reviewed Strickland’s “past medical history, family medical history, daily habits and activities, and health over the past year.” Dusseau issued what he dubbed an “Excellent Report!” Green Party Senate candidate Joseph DeMare is also in excellent health. His doctor, Matt Roth of Maumee, says in a letter provided to the AP that the 54-year-old takes no medication and has no ongoing medical concerns. Claim: Health reports rosy in Ohio’s otherwise ugly US Senate race.
[A]:
There’s rosy news in the nasty, high-stakes battle for Ohio’s U.S. Senate seat: Both Rob Portman and Ted Strickland are in excellent health.