TASK DEFINITION: You are given a background paragraph that describes one or more causal or qualitative relationships such as a relationship in economics or a scientific law and a story that makes use of the concepts or the relationship described in the provided paragraph. You need to come up with a question about the story that requires an understanding of the relationship described in the background paragraph. The generated question should not be answerable without both the background and story. Write a question about the story that requires a relationship in the background paragraph to answer. Check whether your question requires both the background paragraph and the story to answer. If your question can be answered by only one of these, try to rewrite your question so that it requires both. Note that "flipping" a word in the question can give rise to a new question where the answer will be different from the original question. Often, "flipping" a word gives rise to flipping the direction of the relationship, for example, from "increase" to "decrease."
PROBLEM: Background Paragraph: Once again, a mutation is the change in the DNA or RNA sequence. In multicellular organisms, mutations can be subdivided into germline mutations and somatic mutations. Germline mutations occur in the DNA of sex cells, or gametes, and are therefore potentially very serious. These mutations can be passed to the next generation. If the zygote contains the mutation, every cell in the resulting organism will have that mutation. If the mutation results in a disease phenotype, the mutation causes what is called a hereditary disease. Somatic mutations , which occur in somatic, or body, cells, cannot be passed to the next generation (offspring). Mutations present in a somatic cell of an organism will be present (by DNA replication and mitosis) in all descendants of that cell. If the mutation is present in a gene that is not used in that cell type, the mutation may have no effect. On the other hand, the mutation may lead to a serious medical condition such as cancer. 
Story: James' father unfortunately had Huntington's disease. This is a disease that can be passed down from generation to generation. His mother Got cancer at one point but it has been treated and has been eliminated.

SOLUTION: Given Huntington's disease can be passed down from generation to generation, is it a germline mutation or a somatic mutation?

PROBLEM: Background Paragraph: Cholesterol can't dissolve in the blood. It has to be transported to and from the cells by carriers called lipoproteins. Low-density lipoprotein, or LDL, is known as "bad" cholesterol. High-density lipoprotein (HDL) is known as good cholesterol. When too much LDL cholesterol circulates in the blood, it can slowly build up in the inner walls of the arteries that feed the heart and brain. Together with other substances, it can form plaque, and lead to atherosclerosis. If a clot forms and blocks a narrowed artery, a heart attack or stroke can result. Cholesterol comes from the food you eat as well as being made by the body. To lower bad cholesterol, a diet low in saturated fat and dietary cholesterol should be followed. Regular aerobic exercise also lowers LDL cholesterol and increases HDL cholesterol. 
Story: John is a doctor with the local hospital. Earlier today, he was seeing two patients, patient A and patient B. John found out that patient A had more LDL, but patient B had more HDL. He now needs to determine correct treatment for them.

SOLUTION: Which patient would have higher risk of atherosclerosis, patient A or patient B?

PROBLEM: Background Paragraph: Insecticide control of aphids is difficult, as they breed rapidly, so even small areas missed may enable the population to recover promptly. Aphids may occupy the undersides of leaves where spray misses them, while systemic insecticides do not move satisfactorily into flower petals. Finally, some aphid species are resistant to common insecticide classes including carbamates, organophosphates, and pyrethroids.For small backyard infestations, spraying plants thoroughly with a strong water jet every few days may be sufficient protection. An insecticidal soap solution can be an effective household remedy to control aphids, but it only kills aphids on contact and has no residual effect. Soap spray may damage plants, especially at higher concentrations or at temperatures above 32 °C (90 °F); some plant species are sensitive to soap sprays. 
Story: Bill and Jane are two farmers. They both had aphid infestation problems over the last few years, so Bill decided to use many types of insecticides in order to keep the aphids under control. He was only partially successful. Jane didn't do anything about it yet, but she vows to do so in the near future.

SOLUTION:
Which farmer didn't spray any insecticide?