Given a passage with a context and an answer, construct a question on the basis of the information present in the passage. Construct the question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) it answer uses text phrases from the passage. Avoid creating questions that (i) can't be answered correctly without actually understanding the passage and (ii) uses the same words or phrases given in the passage.

Ex Input:
Context: It is recommended that dentists screen for dental anxiety (DA) so that fearful patients may be better managed. The main aim of this study was to determine what dentists are being taught in relation to DA as well as whether and how anxious patients are identified in the clinic.', 'Two hundred and forty-six practising dentists (adjusted response rate = 40.1%), from a random sample of registered Australian dentists, completed a mailed questionnaire.', "Dentists estimated that high DA affected 23.3% of children and 19.4% of adults seen. Only 3.7% of dentists reported using a published scale for screening DA, with the most common reason being lack of awareness (56.5%). Approximately one-half of responding dentists directly asked their patients about DA and this was more common among younger dentists (χ(2) = 7.75, p = 0.021). There were few differences in DA screening by other practitioner or practice characteristics (p > 0.05). Only one-third of dentists had received undergraduate training related to DA and only 41.7% considered this to be 'good' or better. Almost 37% of respondents expressed an interest in future training opportunities.
Answer: The use of formal, validated scales for screening DA is minimal. Training in anxiety management appears to be low and is an area that could be expanded upon.

Ex Output:
Does dental anxiety screening practices and self-reported training need among Australian dentists?


Ex Input:
Context: To compare the frequency of Pap test results in a prospective series of direct to vial ThinPrep tests to a cohort of conventionally prepared tests. To follow-up all test results for a minimum of 2 years and assess performance based on this outcome.', 'All women presenting for either routine screening or colposcopic examination in 2001 were enrolled in the ThinPrep cohort. A similar, population of conventionally prepared tests was extracted from the year 2000 laboratory data. Information on all concurrent and follow-up cervical specimens over the ensuing 2 years was retrieved.', 'The ThinPrep cohort comprised 2288 Pap tests and the conventional, 2211. The frequency of normal [within normal limits (WNL) and benign cellular changes (BCC)] results in the ThinPrep cohort was 6% lower and the frequency of abnormal [> or =atypical squamous cells of undetermined significance (ASCUS)] results was 6.8% higher. Respective ThinPrep and conventional cohort results were 1156 (51%) and 1291 (58%) WNL, 625 (27%) and 561 (25%) BCC, 101 (4%) and 65 (3%) ASCUS, 21 (1%) and 2 (0.1%) atypical glandular cells of undetermined significance, 301 (13%) and 224 (10%) low-grade squamous intraepithelial lesion (LSIL), and 74 (3%) and 40 (2%) high-grade SIL (HSIL) (P < 0.0001). Follow-up was available for nearly 80% of each cohort. LSIL or higher was confirmed in 57.5% (n = 266) of the abnormal ThinPrep and 60.9% (n = 190) of the abnormal conventional tests. The ThinPrep yield of confirmed tests however was almost 50% higher than the conventional test.
Answer: In this population, ThinPrep was superior to the conventional Pap test.

Ex Output:
Does comparative study of the ThinPrep Pap test and conventional cytology result in a Canadian cohort?


Ex Input:
Context: Knowledge of sepsis-related end-organ inflammation in\xa0vivo is limited. We investigated the cytokine response in skin and in serum in sepsis and its relation to multiorgan failure (MOF) and survival.', 'Cytokines were analysed in serum and in suction blister fluid of intact skin of 44 patients with severe sepsis and 15 healthy controls. Blister fluid and serum samples were collected within 48\xa0h of the first sepsis-induced organ failure. This is a substudy of a larger follow-up study on wound healing in sepsis.', 'Cytokine levels were higher in patients with sepsis vs. controls (interleukin [IL]-10, blisters: 65.9 vs. 4.3\xa0pg/ml, P\xa0<\xa00.001, serum: 25.7 vs. 4.5\xa0pg/ml, P\xa0=\xa00.004; IL-6, blisters: 41.9 vs. 0.03\xa0pg/ml, P\xa0<\xa00.001, serum: 45.5 vs. 2.1\xa0pg/ml, P\xa0<\xa00.001). Patients with MOF had higher levels of IL-10 (116.4 vs. 21.3\xa0pg/ml, P\xa0=\xa00.015), IL-4 (0.7 vs. 0.07\xa0pg/ml, P\xa0=\xa00.013) and basic fibroblast growth factor (bFGF) (25.9 vs. 9.5\xa0pg/ml, P\xa0=\xa00.027) in blister fluid than patients without MOF. In blister fluid, survivors had lower levels of IL-10 (43.3 vs. 181.9\xa0pg/ml, P\xa0=\xa00.024) and bFGF (15.8 vs. 31.9\xa0pg/ml, P\xa0=\xa00.006) than non-survivors. In serum, survivors had higher levels of vascular endothelial growth factor (VEGF) (152.2 vs. 14.7\xa0pg/ml, P\xa0=\xa00.012) and lower levels of IL-6 (38.5 vs. 91.1\xa0pg/ml, P\xa0=\xa00.011) than non-survivors. The blister fluid levels of bFGF, TNF and VEGF did not correlate with the serum levels.
Answer: Cytokine responses in skin blister fluid in patients with sepsis differed from those in healthy controls.

Ex Output:

Do blister fluid and serum cytokine levels in severe sepsis in humans reflect skin dysfunction?