Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disease in adults. Classical ALS is characterized by the death of upper and lower motor neurons leading to progressive paralysis. Approximately 10% of ALS patients have familial form of the disease. Numerous different gene mutations have been found in familial cases of ALS, such as mutations in superoxide dismutase 1 (SOD1), TAR DNA-binding protein 43 (TDP-43), fused in sarcoma (FUS), C9ORF72, ubiquilin-2 (UBQLN2), optineurin (OPTN) and others. Multiple animal models were generated to mimic the disease and to test future treatments. However, no animal model fully replicates the spectrum of phenotypes in the human disease and it is difficult to assess how a therapeutic effect in disease models can predict efficacy in humans. Importantly, the genetic and phenotypic heterogeneity of ALS leads to a variety of responses to similar treatment regimens. From this has emerged the concept of personalized medicine (PM), which is a medical scheme that combines study of genetic, environmental and clinical diagnostic testing, including biomarkers, to individualized patient care. In this perspective, we used subgroups of specific ALS-linked gene mutations to go through existing animal models and to provide a comprehensive profile of the differences and similarities between animal models of disease and human disease. Finally, we reviewed application of biomarkers and gene therapies relevant in personalized medicine approach. For instance, this includes viral delivering of antisense oligonucleotide and small interfering RNA in SOD1, TDP-43 and C9orf72 mice models. Promising gene therapies raised possibilities for treating differently the major mutations in familial ALS cases.
Which human disease is associated with mutated UBQLN2

If you wish to become a better reader, here are four important things to remember about reading _ : * Knowing why you are reading or what you are reading to find out will often help you to know whether to read rapidly or slowly. * Some things should be read slowly throughout. Examples are directions for making or doing something, arithmetic problems, science and history books, which are full of important information. You must read such things slowly to remember each important step and understand each important ideas. * Some things should be read rapidly throughout. Examples are simple stories meant for enjoyment, news letters from friends, pieces of news from local, or home-town, papers, telling what is happening to friends and neighbors. * In some of your reading, you must change your speed from fast to slow and slow to fast, as you go along. You will need to read certain pages rapidly and then slow down and do more careful reading when you come to important ideas which must be remembered.
Which should be read slowly according to the passage?

The site of the battle is located near U.S. Highway 56, about three miles east of Baldwin City, and is partially within Robert Hall Pearson Memorial Park, designated by the state of Kansas in honor of one of Brown and Shore's fighters who gave a handwritten account of the battle. Signs placed throughout the battle site point out where the battle began and ended. Efforts are underway to preserve both the Pearson Memorial Park and the Ivan Boyd Prairie Preserve across the road. In 1970, to commemorate the 100th anniversary of the founding of Baldwin City, Baker University professor and playwright Don Mueller and Phyllis E. Braun, Business Manager, produced a musical play entitled The Ballad Of Black Jack to tell the story of the events that led up to the battle. The Ballad Of Black Jack played as part of the city's Maple Leaf Festival from 1970-83 and again from 2001-05. It also played in nearby Lawrence in 1986 and in 2006 and 2007 as a part of Lawrence's Civil War On The Western Frontier program. In 2012 the National Park Service designated the battlefield a National Historic Landmark.

What battlefield is located partially in within Robert Hall Pearson Memorial Park?