In this task, you are given a sentence and a verb from the sentence. Your task is to generate a set of wh-questions starting with who, what, when, where, why, how, how much. The generated questions must contain the verb and the answers to these questions are phrases in the input sentence. The answer to the questions is associated with a specific semantic role. The answer to these questions is associated with a specific semantic role. The questions must use pronouns instead of direct nouns that could be used to refer to various roles present in the sentence. Construct a question in such a way that (i) it is unambiguous, (ii) its answer is unique (iii) its answer is a continuous text span from the paragraph.
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Question: Sentence: When BrdU is integrated into DNA , it is supposed that the bromine deforms the minor groove so that Hoechst dyes can not reach their optimal binding site . 
 Verb: integrated

Answer: what will  be integrated  into something?


Question: Sentence: When BrdU is integrated into DNA , it is supposed that the bromine deforms the minor groove so that Hoechst dyes can not reach their optimal binding site . 
 Verb: reach

Answer: what ca n't  reach something?


Question: Sentence: `` American Guru : A Story of Love , Betrayal and Healing '' , by William Yenner and other former Cohen student contributors , allege authoritarianism , financial manipulation , physical and psychological abuse in Cohen 's community , and discusses the challenges of healing after leaving the community . 
 Verb: leaving

Answer:
what was  left?