instruction:
Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
question:
When the disease recurred conventional amphotericin B was used again, but had to be stopped because of severe side effects.
answer:
adverse drug event


question:
We herein described an additional patient with BCR-ABL (ela2) positive acute lymphoblastic leukemia who developed tumor lysis syndrome after 10-day treatment with imatinib.
answer:
adverse drug event


question:
We describe a case of clozapine-induced seizures in a patient with treatment-resistant schizophrenia.
answer:

adverse drug event