In this task, you are given a context, a subject, a relation, and many options. Based on the context, from the options select the object entity that has the given relation with the subject. Answer with text (not indexes).

[Q]: Context: Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a category of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs), or it may aim to prolong life or to reduce symptoms (palliative chemotherapy). Chemotherapy is one of the major categories of medical oncology (the medical discipline specifically devoted to pharmacotherapy for cancer)., A biopsy is a medical test commonly performed by a surgeon, interventional radiologist, or an interventional cardiologist involving extraction of sample cells or tissues for examination to determine the presence or extent of a disease. The tissue is generally examined under a microscope by a pathologist, and can also be analyzed chemically. When an entire lump or suspicious area is removed, the procedure is called an excisional biopsy. When only a sample of tissue is removed with preservation of the histological architecture of the tissues cells, the procedure is called an incisional biopsy or core biopsy. When a sample of tissue or fluid is removed with a needle in such a way that cells are removed without preserving the histological architecture of the tissue cells, the procedure is called a needle aspiration biopsy. Biopsies are most commonly performed for insight into possible cancerous and inflammatory conditions., Xeroderma pigmentosum (XP) is a rare autosomal recessive genetic disorder of DNA repair in which the ability to repair damage caused by ultraviolet (UV) light is deficient. In extreme cases, "all" exposure to sunlight must be forbidden, no matter how small; as such, individuals with the disease are often colloquially referred to as "Moon child". Multiple basal cell carcinomas (basaliomas) and other skin malignancies frequently occur at a young age in those with XP; metastatic malignant melanoma and squamous cell carcinoma are the two most common causes of death in XP victims. This disease is present in both genders and in all races, with an incidence of 1:250,000 in the United States. XP is roughly six times more common in Japanese people than in other groups., Ivan Yevhenovych Vyshnevskyi ( Ukrainian :    , Russian :    ; born 21 February 1957 in the village of Chortoryia ( today 's Myrolyubivka , Ternopil Raion ) ; died 11 May 1996 in Dnipropetrovsk of melanoma ) was a Ukrainian footballer . He earned 6 caps for the USSR national football team , making his debut on 25 January 1985 in a friendly against Yugoslavia . He was selected for the UEFA Euro 1988 squad , but did not play in any games at the tournament . He is from the region that once belonged to Winiowiecki family that had estates near Zboriv where the village of Vyshnivets is located ., Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Not all tumors are cancerous; benign tumors do not spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss and a change in bowel movements. While these symptoms may indicate cancer, they may have other causes. Over 100 types of cancers affect humans.
Tobacco use is the cause of about 22% of cancer deaths. Another 10% is due to obesity, poor diet, lack of physical activity and drinking alcohol. Other factors include certain infections, exposure to ionizing radiation and environmental pollutants. In the developing world nearly 20% of cancers are due to infections such as hepatitis B, hepatitis C and human papillomavirus (HPV). These factors act, at least partly, by changing the genes of a cell. Typically many genetic changes are required before cancer develops. Approximately 510% of cancers are due to inherited genetic defects from a person's parents. Cancer can be detected by certain signs and symptoms or screening tests. It is then typically further investigated by medical imaging and confirmed by biopsy.
Many cancers can be prevented by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat, and avoiding too much sunlight exposure. Early detection through screening is useful for cervical and colorectal cancer. The benefits of screening in breast cancer are controversial. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy, and targeted therapy. Pain and symptom management are an important part of care. Palliative care is particularly important in people with advanced disease. The chance of survival depends on the type of cancer and extent of disease at the start of treatment. In children under 15 at diagnosis the five-year survival rate in the developed world is on average 80%. For cancer in the United States the average five-year survival rate is 66%.
In 2012 about 14.1 million new cases of cancer occurred globally (not including skin cancer other than melanoma). It caused about 8.2 million deaths or 14.6% of human deaths. The most common types of cancer in males are lung cancer, prostate cancer, colorectal cancer and stomach cancer. In females, the most common types are breast cancer, colorectal cancer, lung cancer and cervical cancer. If skin cancer other than melanoma were included in total new cancers each year it would account for around 40% of cases. In children, acute lymphoblastic leukaemia and brain tumors are most common except in Africa where non-Hodgkin lymphoma occurs more often. In 2012, about 165,000 children under 15 years of age were diagnosed with cancer. The risk of cancer increases significantly with age and many cancers occur more commonly in developed countries. Rates are increasing as more people live to an old age and as lifestyle changes occur in the developing world. The financial costs of cancer were estimated at $1.16 trillion US dollars per year as of 2010.
Definitions.
Cancers are a large family of diseases that involve abnormal cell growth with the potential to invade or spread to other parts of the body. They form a subset of neoplasms. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often form a mass or lump, but may be distributed diffusely., A lymph node or lymph gland, is an ovoid or kidney-shaped organ of the lymphatic system, and of the adaptive immune system, that is widely present throughout the body. They are linked by the lymphatic vessels as a part of the circulatory system. Lymph nodes are major sites of B and T lymphocytes, and other white blood cells. Lymph nodes are important for the proper functioning of the immune system, acting as filters for foreign particles and cancer cells. Lymph nodes do not have a detoxification function, which is primarily dealt with by the liver and kidneys., Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is therapy using ionizing radiation, generally as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology., Melanoma, also known as malignant melanoma, is a type of cancer that develops from the pigment-containing cells known as melanocytes. Melanomas typically occur in the skin but may rarely occur in the mouth, intestines, or eye. In women they most commonly occur on the legs, while in men they are most common on the back. Sometimes they develop from a mole with concerning changes including an increase in size, irregular edges, change in color, itchiness, or skin breakdown.
The primary cause of melanoma is ultraviolet light (UV) exposure in those with low levels of skin pigment. The UV light may be from either the sun or from other sources, such as tanning devices. About 25% develop from moles. Those with many moles, a history of affected family members, and who have poor immune function are at greater risk. A number of rare genetic defects such as xeroderma pigmentosum also increase risk. Diagnosis is by biopsy of any concerning skin lesion.
Using sunscreen and avoiding UV light may prevent melanoma. Treatment is typically removal by surgery. In those with slightly larger cancers, nearby lymph nodes may be tested for spread. Most people are cured if spread has not occurred. For those in whom melanoma has spread, immunotherapy, biologic therapy, radiation therapy, or chemotherapy may improve survival. With treatment the five-year survival rates in the United States is 98% among those with localized disease and 17% among those in whom spread has occurred. The likelihood that it will come back or spread depends how thick the melanoma is, how fast the cells are dividing, and whether or not the overlying skin has broken down.
Melanoma is the most dangerous type of skin cancer. Globally, in 2012, it occurred in 232,000 people and resulted in 55,000 deaths. Australia and New Zealand have the highest rates of melanoma in the world. There are also high rates in Northern Europe and North America, while it is less common in Asia, Africa, and Latin America. Melanoma is more common in men than women. Melanoma has become more common since the 1960s in areas that are mostly Caucasian., Subject: ivan vyshnevskyi, Relation: cause_of_death, Options: (A) bleeding (B) breast cancer (C) cancer (D) carcinoma (E) disease (F) hepatitis (G) lung cancer (H) melanoma (I) old age (J) skin cancer (K) tumor
[A]: skin cancer


[Q]: Context: The Northern Territory (abbreviated as NT) is a federal Australian territory in the central and central northern regions of Australia. It shares borders with Western Australia to the west (129th meridian east), South Australia to the south (26th parallel south), and Queensland to the east (138th meridian east). To the north, the territory is bordered by the Timor Sea, the Arafura Sea and the Gulf of Carpentaria. Despite its large areaover , making it the third largest Australian federal divisionit is sparsely populated. The Northern Territory's population of 244,000 (2016) makes it the least populous of Australia's eight major states and territories, having fewer than half as many people as Tasmania., A sea is a large body of salt water that is surrounded in whole or in part by land. More broadly, "the sea" is the interconnected system of Earth's salty, oceanic watersconsidered as one global ocean or as several principal oceanic divisions. The sea moderates Earth's climate and has important roles in the water cycle, carbon cycle, and nitrogen cycle. Although the sea has been traveled and explored since prehistory, the modern scientific study of the seaoceanographydates broadly to the British "Challenger" expedition of the 1870s. The sea is conventionally divided into up to five large oceanic sectionsincluding the International Hydrographic Organization's four named oceans (the Atlantic, Pacific, Indian, and Arctic) and the Southern Ocean; smaller, second-order sections, such as the Mediterranean, are known as "seas"., A river is a natural flowing watercourse, usually freshwater, flowing towards an ocean, sea, lake or another river. In some cases a river flows into the ground and becomes dry at the end of its course without reaching another body of water. Small rivers can be referred to using names such as stream, creek, brook, rivulet, and rill. There are no official definitions for the generic term river as applied to geographic features, although in some countries or communities a stream is defined by its size. Many names for small rivers are specific to geographic location; examples are "run" in some parts of the United States, "burn" in Scotland and northeast England, and "beck" in northern England. Sometimes a river is defined as being larger than a creek, but not always: the language is vague., The Meda River is a river in the Kimberley of Western Australia . The river is formed when the Lennard River splits into two channels just north of Mount Marmion , the other channel being the May River . Continuing to flow westward the river eventually discharges into Stokes Bay , King Sound which is north - east of Derby . The river was named in 1881 by a pioneer of the area , George Julius Brockman during an expedition in the Kimberley area . The river is named after HMS Meda , an Admiralty surveying vessel that charted the coastline in the area including the river mouth in 1880 . The traditional owners of the areas around the river are the Ongkarango peoples . The Meda has three tributaries ; The Lennard River , May River and Hawkstone Creek ., The Indian Ocean is the third largest of the world's oceanic divisions, covering (approximately 20% of the water on the Earth's surface). It is bounded by Asia on the north, on the west by Africa, on the east by Australia, and on the south by the Southern Ocean or, depending on definition, by Antarctica. It is named after the country of India. The Indian Ocean is known as "Ratnkara", ""the mine of gems"" in ancient Sanskrit literature, and as "Hind Mahsgar", ""the great Indian sea"", in Hindi., The Great Australian Bight is a large oceanic bight, or open bay, off the central and western portions of the southern coastline of mainland Australia., The Southern Ocean, also known as the Antarctic Ocean or the Austral Ocean, comprises the southernmost waters of the World Ocean, generally taken to be south of 60° S latitude and encircling Antarctica. As such, it is regarded as the fourth-largest of the five principal oceanic divisions: smaller than the Pacific, Atlantic, and Indian Oceans but larger than the Arctic Ocean. This ocean zone is where cold, northward flowing waters from the Antarctic mix with warmer subantarctic waters., Western Australia (abbreviated as WA) is a state occupying the entire western third of Australia. It is bounded by the Indian Ocean to the north and west, the Great Australian Bight and Southern Ocean to the south, the Northern Territory to the north-east and South Australia to the south-east. Western Australia is Australia's largest state with a total land area of 2,529,875 square kilometres (976,790 sq mi), and the second-largest country subdivision in the world  however, a significant part of it is sparsely populated. The state has about 2.6 million inhabitants, around 11% of the national total. 92% of the population lives in the south-west corner of the state., An ocean (the sea of classical antiquity) is a body of saline water that composes much of a planet's hydrosphere. On Earth, an ocean is one of the major conventional divisions of the World Ocean, which covers almost 71% of its surface. These are, in descending order by area, the Pacific, Atlantic, Indian, Southern (Antarctic), and Arctic Oceans. The word "sea" is often used interchangeably with "ocean" in American English but, strictly speaking, a sea is a body of saline water (generally a division of the world ocean) partly or fully enclosed by land., Subject: meda river, Relation: mouth_of_the_watercourse, Options: (A) arafura sea (B) arctic ocean (C) great australian bight (D) indian ocean (E) sea (F) southern ocean (G) timor sea
[A]: indian ocean


[Q]: Context: A U.S. state is a constituent political entity of the United States of America. There are 50 states, which are bound together in a union with each other. Each state holds administrative jurisdiction over a defined geographic territory, and shares its sovereignty with the United States federal government. Due to the shared sovereignty between each state and the federal government, Americans are citizens of both the federal republic and of the state in which they reside. State citizenship and residency are flexible, and no government approval is required to move between states, except for persons covered by certain types of court orders (e.g., paroled convicts and children of divorced spouses who are sharing custody)., The Page Valley is a small valley geographically and culturally associated with the Shenandoah Valley. The valley is located between the Massanutten and Blue Ridge mountain ranges in western Virginia., The Potomac River is located along the mid-Atlantic Ocean coast of the United States and flows into the Chesapeake Bay. The river (main stem and North Branch) is approximately long, with a drainage area of about 14,700 square miles (38,000 km²). In terms of area, this makes the Potomac River the fourth largest river along the Atlantic coast of the United States and the 21st largest in the United States. Over 5 million people live within the Potomac watershed., West Virginia is a state located in the Appalachian region of the Southern United States. It is bordered by Virginia to the southeast, Kentucky to the southwest, Ohio to the northwest, Pennsylvania to the north (and, slightly, east), and Maryland to the northeast. West Virginia is the 41st largest by area, the 38th most populous, and has the second lowest household income of the 50 United States. The capital and largest city is Charleston., Virginia (, officially the Commonwealth of Virginia) is a state located in the Mid-Atlantic region of the United States, as well as in the historic Southeast. Virginia is nicknamed the "Old Dominion" due to its status as the first colonial possession established in mainland British America, and "Mother of Presidents" because eight U.S. presidents were born there, more than any other state. The geography and climate of the Commonwealth are shaped by the Blue Ridge Mountains and the Chesapeake Bay, which provide habitat for much of its flora and fauna. The capital of the Commonwealth is Richmond; Virginia Beach is the most populous city, and Fairfax County is the most populous political subdivision. The Commonwealth's estimated population is over 8.3 million, which is slightly less than New York City., The Shenandoah River is a tributary of the Potomac River, long with two forks approximately long each, in the U.S. states of Virginia and West Virginia. The principal tributary of the Potomac, the river and its tributaries drain the central and lower Shenandoah Valley and the Page Valley in the Appalachians on the west side of the Blue Ridge Mountains, in northwestern Virginia and the Eastern Panhandle of West Virginia., A tributary or affluent is a stream or river that flows into a larger stream or main stem (or parent) river or a lake. A tributary does not flow directly into a sea or ocean. Tributaries and the main stem river drain the surrounding drainage basin of its surface water and groundwater, leading the water out into an ocean., Hopewell , also known as Hopewell Mills and Hopewell Farm , was established around 1765 by William Little , Sr. , who built grain and saw mills near the Shenandoah River . In 1827 , William Little , Jr. sold the property to James Hite and Jacob Newcomer . Hite named the property `` Hopewell '' , identifying the mill with a place in Leetown also named Hopewell , where there was a Quaker meeting house . Hite 's descendant , Thomas Hite Willis , operated and expanded the mill , adding a woolen mill. The woolen mill operated until the 1920s providing uniforms for the Army . The complex includes a log - and - clapboard house , built circa 1765 with twentieth century additions , a tenant house ( known as the `` Viand Cottage '' ) from the same era and of similar construction , several outbuildings and the ruins of the woolen mill , circa 1850 ., The Shenandoah Valley is a geographic valley and cultural region of western Virginia and the Eastern Panhandle of West Virginia in the United States. The valley is bounded to the east by the Blue Ridge Mountains, to the west by the eastern front of the Ridge-and-Valley Appalachians (excluding Massanutten Mountain), to the north by the Potomac River and to the south by the James River. The cultural region covers a larger area that includes all of the valley plus the Virginia highlands to the west, and the Roanoke Valley to the south. It is physiographically located within the Ridge and Valley province and is a portion of the Great Appalachian Valley., The Blue Ridge Mountains are a physiographic province of the larger Appalachian Mountains range. This province consists of northern and southern physiographic regions, which divide near the Roanoke River gap. The mountain range is located in the eastern United States, starting at its southernmost portion in Georgia, then ending northward in Pennsylvania. To the west of the Blue Ridge, between it and the bulk of the Appalachians, lies the Great Appalachian Valley, bordered on the west by the Ridge and Valley province of the Appalachian range., Subject: hopewell , Relation: located_in_the_administrative_territorial_entity, Options: (A) atlantic ocean (B) basin (C) central (D) charleston (E) fairfax county (F) gap (G) georgia (H) kentucky (I) mainland (J) maryland (K) most (L) northern (M) of (N) river (O) shenandoah (P) south (Q) the valley (R) union (S) virginia (T) virginia beach (U) west virginia (V) york
[A]:
west virginia