In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

[Q]: Bats have been recognized as the natural reservoirs of a large variety of viruses. Special attention has been paid to bat coronaviruses as the two emerging coronaviruses which have caused unexpected human disease outbreaks in the 21st century, Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV), are suggested to be originated from bats. Various species of horseshoe bats in China have been found to harbor genetically diverse SARS-like coronaviruses. Some strains are highly similar to SARS-CoV even in the spike protein and are able to use the same receptor as SARS-CoV for cell entry. On the other hand, diverse coronaviruses phylogenetically related to MERS-CoV have been discovered worldwide in a wide range of bat species, some of which can be classified to the same coronavirus species as MERS-CoV. Coronaviruses genetically related to human coronavirus 229E and NL63 have been detected in bats as well. Moreover, intermediate hosts are believed to play an important role in the transmission and emergence of these coronaviruses from bats to humans. Understanding the bat origin of human coronaviruses is helpful for the prediction and prevention of another pandemic emergence in the future.
[A]: Bat origin of human coronaviruses


[Q]: Background: Respiratory syncytial virus (RSV), human Rhinovirus (HRV) and human Metapneumo Virus (HMPV) are important viral pathogens causing acute respiratory tract infections in the hospitalized patients. Sensitive and accurate detection of RSV, HRV and HMPV is necessary for clinical diagnosis and treatment. Results: A locked nucleic acid (LNA)-based multiplex closed one-tube nested real-time RT-PCR (mOTNRT-PCR) assay was developed for simultaneous detection of RSV, HRV and HMPV. The sensitivity, specificity, reproducibility and clinical performance of mOTNRT-PCR were evaluated and compared with individual real time PCR (RT-qPCR) assay using clinical samples. The analytical sensitivity of mOTNRT-PCR assay was 5 copies/reaction for RSV, HRV and HMPV, respectively, and no cross-reaction with other common respiratory viruses was observed. The coefficients of variation (CV) of intra-assay and inter-assay were between 0.51 to 3.67%. Of 398 nasopharyngeal aspirates samples tested, 109 (27.39%), 150 (37.69%) and 44 (11.06%) were positive for RSV, HRV and HMPV, respectively, whereas 95 (23.87%), 137 (34.42%) and 38 (9.55%) were positive for RSV, HRV and HMPV, respectively, by individual RT-qPCR assay. Thirty three samples that were positive by mOTNRT-PCR but negative by RT-qPCR were confirmed as true positives by sequencing using reported traditional two-step nested PCR assay. Conclusion: mOTNRT-PCR assay reveals extremely higher sensitivity than that of RT-qPCR assay for detecting RSV, HRV and HMPV in clinical settings.
[A]: A multiplex one-tube nested real time RT- PCR assay for simultaneous detection of respiratory syncytial virus, human rhinovirus and human metapneumovirus


[Q]: publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. Figure 57-1 Functional anatomy of the small intestine. A, Anatomic arrangement of the small intestine. B, The small intestine is basically a tube with a serosal surface covered by visceral peritoneum and an inner absorptive and digestive surface, the mucosa. C, Beneath the outer serosa, longitudinal and circular muscle layers produce peristaltic and segmental contractions for propelling and mixing the luminal contents. The submucosa is rich in blood and lymphatic vessels. The mucosa comprises the thin muscularis mucosa, the lamina propria, and the columnar epithelium; it is thrown into folds and is covered by finger-like villi to increase the digestive and absorptive surface area. D, Enterocytes, which are shed from the villus tip but are continually replaced through division of crypt cells, are the site of nutrient digestion and absorption. Goblet cells secrete protective mucus. Water-soluble nutrients pass into the rich capillary network of the lamina propria, and fat is passed as chylomicrons into the lacteals. Immunocytes in the lamina propria are involved in maintaining tolerance to luminal antigens. E, The luminal membrane of the enterocyte is thrown into processes called microvilli, which increase the luminal surface area. Tight junctions between enterocytes maintain epithelial integrity. Absorbed nutrients are passed from the enterocyte into the intercellular space for distribution to the body. F, Schematic of a microvillus showing digestive hydrolases anchored in the phospholipid cell membrane and protruding into the intestinal lumen. Carrier proteins in the membrane are believed to act as "pores," shuttling nutrients across the membrane by means of conformational changes in their structure often induced by sodium influx at the expense of energy utilization through Na/K-adenosine triphosphatase (ATPase) on the basolateral membrane.
[A]:
Small Intestine STRUCTURE AND FUNCTION