In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Input: Consider Input: Paragraph: The open reading frame 3 of the severe acute respiratory syndrome coronavirus (SARS-CoV) genome encodes a predicted protein 3a, consisting of 274 amino acids, that lacks any significant similarities to any known protein. We generated specific antibodies against SARS protein 3a by using a synthetic peptide (P2) corresponding to amino acids 261-274 of the putative protein. Anti-P2 antibodies and the sera from SARS patients could specifically detect the recombinant SARS protein 3a expressed in Escherichia coli and in Vero E6 cells. Expression of SARS protein 3a was detected at 8-12 h after infection and reached a higher level after $24 h in SARS-CoV-infected Vero E6 cells. Protein 3a was also detected in the alveolar lining pneumocytes and some intra-alveolar cells of a SARS-CoVinfected patient's lung specimen. Recombinant protein 3a expressed in Vero E6 cells and protein 3a in the SARS-CoVinfected cells was distributed over the cytoplasm in a fine punctate pattern with partly concentrated staining in the Golgi apparatus. Our study demonstrates that SARS-CoV indeed expresses a novel protein 3a, which is present only in SARS-CoV and not in other known CoVs. 
 Title: Identification of a novel protein 3a from severe acute respiratory syndrome coronavirus

Output: False


Input: Consider Input: Paragraph: Background: Positive controls are an integral component of any sensitive molecular diagnostic tool, but this can be affected, if several mutations are being screened in a scenario of a pandemic or newly emerging disease where it can be difficult to acquire all the necessary positive controls from the host. This work describes the development of a synthetic oligo-cassette for positive controls for accurate and highly sensitive diagnosis of several mutations relevant to influenza virus drug resistance. Results: Using influenza antiviral drug resistance mutations as an example by employing the utility of synthetic paired long oligonucleotides containing complementary sequences at their 3' ends and utilizing the formation of oligonucleotide dimers and DNA polymerization, we generated~170bp dsDNA containing several known specific neuraminidase inhibitor (NAI) resistance mutations. These templates were further cloned and successfully applied as positive controls in downstream assays. Conclusion: This approach significantly improved the development of diagnosis of resistance mutations in terms of time, accuracy, efficiency and sensitivity, which are paramount to monitoring the emergence and spread of antiviral drug resistant influenza strains. Thus, this may have a significantly broader application in molecular diagnostics along with its application in rapid molecular testing of all relevant mutations in an event of pandemic. 
 Title: Synthetic long oligonucleotides to generate artificial templates for use as positive controls in molecular assays: drug resistance mutations in influenza virus as an example

Output: False


Input: Consider Input: Paragraph: The gold standard for diagnosis of 2019 novel coronavirus (2019-nCoV) infection is the new coronavirus nucleic acid in swabs, sputum, secretions from the lower respiratory tract or blood. However, due to the quite low sensitivity, short of supply and a relatively long period of new coronavirus nucleic acid kits, suspected cases with false-negative results remain a severe problem. Besides, a long incubation period (3-7 days, up to 14 days) and superior transmission capacity of new viruses contribute to the fast spread of 2019-nCoV. Under the circumstances, computed tomography imaging is not only useful for the detection, location of lesions but also helpful in the evaluation of the dynamic changes of patients with 2019-nCoV. A 47-year-old man had a history of cough, sputum production, sore throat and throbbing headache for 3 days without fever. He has been living in Chengdu, Sichuan province, for a long time. However, his mother had traveled to Wuhan a week ago and was diagnosed with the new coronavirus after she got back home. He has referred to the emergency department of our institution on 2 February 2020. General physical examination showed that moist rales were audible over both lungs, and the body temperature was 36.7 C, and other results were unremarkable. The laboratory tests showed that white blood cell count kept in the normal range (5.11 Â 109/l), and the differential count showed decreased lymphocyte (16.8%, normal range 20-50%) and increased C-reactive protein (22.50 mg/l; normal range <5 mg/l). Chest computed tomography (CT) (2 February 2020) showed that there were ground-glass opacities, consolidation or both in bilateral lungs ( Figure 1A ). Considering the contact history with his mother and the CT features, a real-time fluorescence polymerase chain reaction of the patient's throat Figure 1. Chest CT images in a 47-year-old man. (A) CT images show that there are ground-glass opacities, consolidation or both in bilateral lungs, and 'halo sign' is visible in the basal segment of the lower lobe of the right lung. (B) The extent and density of lesions are significantly decreased. (C and D) At the third time of reexamination, CT scan shows multiple patchy ground-glass opacities, consolidation in bilateral lungs and the new lesions are in different locations. 
 Title: Author(s) QJM


Output: True