Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
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Question: Bone, as well as the lung and liver, is among the sites of predilection for cancer metastasis. The bone stores large amounts of growth factors such as insulin-like growth factors and transforming growth factor-b, and provides fertile soil for metastatic cancer cells by continuously releasing these bone-stored growth factors, which are a consequence of osteoclastic bone resorption. Metastatic cancer cells in turn produce osteoclast-stimulating cytokines such as parathyroid hormone-related protein( PTH-rP), prostaglandin E2.(PGE2), and various interleukins(ILs). These cancer-produced osteoclast-stimulating cytokines bind to their cognitive receptors and promote the expression of ligands for the receptor activators of nuclear factor kB (RANKL)in osteoblasts. RANKL then binds to its receptor RANK, expressed in pre-osteoclasts, stimulates mature osteoclast formation, and subsequently, osteoclastic bone resorption. This vicious cycle between metastatic cancer cells and osteoclasts is critical to the development and progression of bone metastases. In addition, it is likely that metastatic cancer cells are influenced by bone environments(or niche)and acquire additional capacities such as an epithelial-mesenchymal transition(EMT), allowing them to be resistant to chemotherapy or apoptosis, to survive in a dormant state, or to aggressively spread to distant organs including lung and liver. Thus, the bone can serve as transit port. Disrupting this cycle by inhibiting osteoclastic bone resorption, antagonizing bone-derived growth factors, and neutralizing RANKL or PTH-rP, should be a promising therapeutic intervention for bone metastases. Bisphosphonates(BP)are specific inhibitors of osteoclasts, and have been shown to significantly reduce skeletal-related events(SRE)associated with bone metastasis. Denosumab is a neutralizing monoclonal antibody to RANKL and has recently been found to inhibit SRE more effectively than BP. Further understanding of the crosstalk communication between metastatic cancer cells and bone at the molecular level should lead us to design novel, more effective and specific treatments for cancer patients with bone metastases.

Answer: To the ligand of which receptors does Denosumab (Prolia) bind?


Question: Scelsi Morning is a 2003 album by Marc Ribot released on Tzadik Records.

Answer: What is the name of Scelsi Morning's record label?


Question: The film opens with an animated prologue revealing the origins of leprechauns, stating that they were summoned by a king to protect his gold from those who would try to steal it. After the death of the king the Leprechauns returned to their places of origin, all except one (Warwick Davis) who remained in the mortal world and through the ages slowly became corrupted and obsessed with the treasure he still guarded. In the present Father Jacob (Willie C. Carpenter) is chased through the construction site of the youth center he had planned on building by the Leprechaun, whose gold Jacob had taken to fund the building project. Using four-leaf clover laced holy water Jacob manages to banish the Leprechaun, summoning demonic hands which drag him underground, but soon after drops dead of injuries inflicted by the Leprechaun during the fight.One year later two down on their luck friends Emily Woodrow (Tangi Miller) and Lisa Duncan (Sherrie Jackson) have their fortune told when the clairvoyant Esmeralda (Donzaleigh Abernathy) who warns them that they will attain great wealth soon, but it must be denied as it will come at a great price and summon a terrible evil. While having a barbecue at the abandoned youth center construction site with Lisa, their stoner friend Jamie Davis (Page Kennedy) and her ex-boyfriend turned drug dealer Rory Jackson (Laz Alonso) Emily falls through a hole and discovers the Leprechaun's gold in an old tunnel where it was hidden by Father Jacob. Splitting up the gold (which is produced in a never ending amount by the chest it was contained in) evenly the quartet of friends use it to fulfill their fantasies, unaware that by taking the gold they have released the Leprechaun, who begins stalking the group (killing a guest who takes one of his coins at a party held by Jamie, prompting the police to temporarily arrest him). At the salon where Emily works the Leprechaun sneaks in and, after killing a regular customer, Doria, on the massage table by breaking her neck, attacks Emily, who barely escapes and warns Rory and the recently released Jamie, who rush to get to Lisa's. In her house Lisa is attacked by the Leprechaun and manages to fight him off for a short while, but is killed when the Leprechaun claws her in the stomach, with her friends finding her body moments later.While Emily and Jamie want to return the gold Rory does not and takes off with it; shortly after realizing Rory is gone Emily is attacked and chased outside by the Leprechaun, but is saved when Rory has a change of heart and comes back for her. Searching for Rory the Leprechaun stops by his house and kills Rory's profligate girlfriend Chanel (Keesha Sharp) by tearing out her upper jaw, reclaiming the gold she used to make a tooth while Rory and Emily are stopped and harassed by Officers Thompson (Beau Billingslea) and Whitaker (Chris Murray). After the Leprechaun appears and kills the two officers Emily and Rory escape and regroup with Jamie, only to be confronted by a machine gun wielding group of Rory's drug dealing rivals, led by Watson (Shiek Mahmud-Bey) and Cedric (Sticky Fingaz). Planning on executing Rory for infringing on their territory Watson and his gang are all disposed of by the Leprechaun, (who kills Watson and Cedric while the other two members run off) while Emily, Rory and Jamie drive off in Watson's car (which the Leprechaun latches to the bottom of for a short while) and go looking for help from Esmeralda.Advised to use four-leaf clovers against the Leprechaun by Esmeralda, Rory laces the hollow-point bullets of his gun with clovers Jamie finds in the marijuana Rory had earlier sold him. When the Leprechaun arrives Rory shoots him several times with the clover bullets, only for his gun to jam before he can finish the Leprechaun off. Rory and Emily are given the chance to run with the gold when the Leprechaun is distracted by Jamie and Esmeralda (the latter dying in a magical duel with the Leprechaun). Followed to the roof of the building Rory tries fighting the Leprechaun and is knocked out, though before the Leprechaun can kill him

Answer:
who does rory try fighting?