Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

[EX Q]: Context: Charles Wilson Cross died of a heart attack June 2, 1928, in Calgary. 
 Question: What was Charles Wilson Cross's cause of death?
[EX A]: heart attack

[EX Q]: Context: Assume that a school bus, like the one in Figure 12.2, passes by as you stand on the sidewalk. Its obvious to you that the bus is moving. It is moving relative to you and the trees across the street. But what about to the children inside the bus? They arent moving relative to each other. If they look only at the other children sitting near them, they will not appear to be moving. They may only be able to tell that the bus is moving by looking out the window and seeing you and the trees whizzing by. This example shows that how we perceive motion depends on our frame of reference. Frame of reference refers to something that is not moving with respect to an observer that can be used to detect motion. For the children on the bus, if they use other children riding the bus as their frame of reference, they do not appear to be moving. But if they use objects outside the bus as their frame of reference, they can tell they are moving. What is your frame of reference if you are standing on the sidewalk and see the bus go by? How can you tell the bus is moving? The video at the URL below illustrates other examples of how frame of reference is related to motion. MEDIA Click image to the left or use the URL below. URL: Did you ever go to a track meet like the one pictured in Figure 12.3? Running events in track include 100-meter sprints and 2000-meter races. Races are named for their distance. Distance is the length of the route between two points. The length of the route in a race is the distance between the starting and finishing lines. In a 100-meter sprint, for example, the distance is 100 meters. The SI unit for distance is the meter (1 m = 3.28 ft). Short distances may be measured in centimeters (1 cm = 0.01 m). Long distances may be measured in kilometers (1 km = 1000 m). For example, you might measure the distance a frogs tongue moves in centimeters and the distance a cheetah moves in kilometers. Maps can often be used to measure distance. Look at the map in Figure 12.4. Find Mias house and the school. You can use the map key to directly measure the distance between these two points. The distance is 2 kilometers. Measure it yourself to see if you agree. Things dont always move in straight lines like the route from Mias house to the school. Sometimes they change direction as they move. For example, the route from Mias house to the post office changes from west to north at the school (see Figure 12.4). To find the total distance of a route that changes direction, you must add up the distances traveled in each direction. From Mias house to the school, for example, the distance is 2 kilometers. From the school to the post office, the distance is 1 kilometer. Therefore, the total distance from Mias house to the post office is 3 kilometers. You Try It! Problem: What is the distance from the post office to the park in Figure 12.4? Direction is just as important as distance in describing motion. For example, if Mia told a friend how to reach the post office from her house, she couldnt just say, "go 3 kilometers." The friend might end up at the park instead of the post office. Mia would have to be more specific. She could say, "go west for 2 kilometers and then go north for 1 kilometer." When both distance and direction are considered, motion is a vector. A vector is a quantity that includes both size and direction. A vector is represented by an arrow. The length of the arrow represents distance. The way the arrow points shows direction. The red arrows in Figure 12.4 are vectors for Mias route to the school and post office. If you want to learn more about vectors, watch the videos at these URLs: (5:27) MEDIA Click image to the left or use the URL below. URL: You Try It! Problem: Draw vectors to 
 Question: When both distance and direction are considered, motion
[EX A]: is a vector.

[EX Q]: Context: A dedicated excision repair pathway, termed transcription-coupled repair (TCR), targets the removal of DNA lesions from transcribed strands of expressed genes. Transcription arrest at the site of the lesion has been proposed as the first step for initiation of TCR. In support of this model, a strong correlation between arrest of transcription by a lesion in vitro and TCR of that lesion in vivo has been found in most cases analyzed. TCR has been reported for oxidative DNA damage; however, very little is known about how frequently occurring and spontaneous DNA damage, such as depurination and base deamination, affects progression of the transcription complex. We have previously determined that the oxidative lesion, thymine glycol, is a significant block to transcription by T7 RNA polymerase (T7 RNAP) but has no detectable effect on transcription by RNA polymerase II (RNAP II) in a reconstituted system with all of the required factors. Another oxidative lesion, 8-oxoguanine, only slightly blocked T7 RNAP and caused RNAP II to briefly pause at the lesion before bypassing it. Because an abasic site is an intermediate in the repair of oxidative damage, it was of interest to learn whether it arrested transcription. Using in vitro transcription assays and substrates containing a specifically positioned lesion, we found that an abasic site in the transcribed strand is a 60% block to transcription by T7 RNAP but nearly a complete block to transcription by mammalian RNAP II. An abasic site in the nontranscribed strand did not block either polymerase. Our results clearly indicate that an abasic site is a much stronger block to transcription than either a thymine glycol or an 8-oxoguanine. Because the predominant model for TCR postulates that only lesions that block RNAP will be subject to TCR, our findings suggest that the abasic site may be sufficient to initiate TCR in vivo. 
 Question: Which gene strand is targeted by transcription-coupled repair (TCR)?
[EX A]:
the transcribed strand