Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Context: NADPH oxidase (Nox) family enzymes are one of the main sources of cellular reactive oxygen species (ROS), which have been shown to function as second messenger molecules. To date, seven members of this family have been reported, including Nox1-5 and Duox1 and -2. With the exception of Nox2, the regulation of the Nox enzymes is still poorly understood. Nox1 is highly expressed in the colon, and it requires two cytosolic regulators, NoxO1 and NoxA1, as well as the binding of Rac1 GTPase, for its activity. In this study, we investigate the role of the tyrosine kinase c-Src in the regulation of ROS formation by Nox1. We show that c-Src induces Nox1-mediated ROS generation in the HT29 human colon carcinoma cell line through a Rac-dependent mechanism. Treatment of HT29 cells with the Src inhibitor PP2, expression of a kinase-inactive form of c-Src, and c-Src depletion by small interfering RNA (siRNA) reduce both ROS generation and the levels of active Rac1. This is associated with decreased Src-mediated phosphorylation and activation of the Rac1-guanine nucleotide exchange factor Vav2. Consistent with this, Vav2 siRNA that specifically reduces endogenous Vav2 protein is able to dramatically decrease Nox1-dependent ROS generation and abolish c-Src-induced Nox1 activity. Together, these results establish c-Src as an important regulator of Nox1 activity, and they may provide insight into the mechanisms of tumor formation in colon cancers. 
 Question: Which NADPH oxidase family member requires interaction with NOXO1 for function?
nadph oxidase 1

Context: The film Calvary is a parable of the betrayal of the Irish people by the Irish Catholic Church.Context for the story: The Irish Catholic Church which was a pillar of, and defined Ireland's soul has been revealed to have consciously and methodically covered up institutional atrocities perpetrated by themselves.Set in rural Ireland, the film begins in a confessional where Father James Lavelle (Brendan Gleeson) is taking confession. The voice on the other side speaks, "I was seven the first time I tasted semen". "Certainly a startling opening line", Father James replies. The voice asks if he's being ironic. Father James takes a more serious tone. The voice tells him that he was molested both orally and anally by a priest when he was seven and he bled a lot. Father James asks if he would like to report the priest. The voice says that the priest died a long time ago and that it didn't matter. "Killing a bad priest isn't a big deal, but if you kill a good priest, people take notice". The voice says he's going to kill Father James in seven days on the beach.James lives a very simple life. He sleeps in a small room with a bed and his only two possessions are his crucifix and his dog. He takes walks on the beach and interacts with the town people. On the beach, he sees his altar server is drawing a landscape. In it there are two figures. James asks who they are and the boy says he doesn't know, but he has been having a lot of dreams about ghosts lately.After mass, Father James is speaking with Father Leary (David Wilmot) who is gossiping about the townsfolk, sharing information he's heard in confession and making racially inappropriate comments about Simon (Isaach De Bankole) the only black man in the town. Father James doesn't say a word about the threat on his life.James' daughter Fiona (Kelly Reilly) comes to town to lay low after a botched suicide attempt. The townsfolk didn't know it was possible for a Catholic priest to have a daughter. James explains that he became a priest after his wife died. The locals in the pub try to flirt with Fiona, but she has no interest. James does not drink. Its not because he doesn't like alcohol. Its because he likes it too much.Later in the day, James visits with Veronica Brennan (Orla ORourke) who was wearing sunglasses during mass to cover up her black eye. She says her husband did it. So James goes to meet her husband, the local butcher Jack Brennan (Chris O'Dowd) and confronts him. Jack is surprised, but good natured about the whole thing. He dismisses his wife by saying she's probably bi-polar. He says it wasn't him, but it might have been her boyfriend Simon. James questions the infidelity, but Jack explains that it works for them. They each do their own thing. James meets with Simon, who takes offense to the charge and passively threatens James and tells him to mind his own business.James spends time with an elderly man known only as The Writer (M. Emmet Walsh) who asks for a Walther PPK, James Bonds favorite gun and the gun Hitler used to kill himself. The Writer explains that he doesn't want to get old and feeble. He'd rather just take his own life when the time is right.James meets with the local Bishop and tells him about the threat during the confession. He also reveals that he knows who the man is and believes the threat is real. The Bishop says that because the man didn't ask for repentance and there was the threat of a law being broken, James would not violate and church law in speaking with the police.James goes to speak with his friend Inspector Stanton (Gary Lydon), who seems to be spending some time with a male prostitute named Leo (Owen Sharpe). Leo keeps making lewd advances on James and offers to have sex with him in his vestments because he knows that's what priests like. Eventually Leo leaves and 
 Question: Who does James talk to?
jack brennan

Context: The movie is based on the true story of two British athletes competing in the 1924 Summer Olympics in Paris. Englishman Harold Abrahams (Ben Cross), who is Jewish, overcomes anti-Semitism and class prejudice in order to compete against the "Flying Scotsman", Eric Liddell (Ian Charleson), in the 100 metre race.Opening in 1919 England, Harold Abrahams enters Cambridge University, where he meets with anti-Semitism from the staff, but enjoys participating in the Gilbert and Sullivan theatre club. He becomes the first person to ever complete the Trinity Great Court run: running around the court in the time it takes for the clock to strike 12. Abrahams achieves an undefeated string of victories in various national running competitions. Although focused on his running, he falls in love with a famous Gilbert and Sullivan soprano, Sybil (Alice Krige).Meanwhile in Scotland, Eric Liddell (Ian Charleson), born in China of Scottish missionary parents, is in Scotland. His devout sister Jennie (Cheryl Campbell) disapproves of Liddell's plans to pursue competitive running. But Liddell sees running as a way of glorifying God before returning to China to work as a missionary.Abrahams and Liddell meet for the first time in London in June 1923 when they first race against each other in a British open. Liddell beats Abrahams who takes it extremely badly. But Sam Mussabini (Ian Holm), a professional trainer whom Abrahams had approached earlier, offers to take him on to improve his technique. This attracts criticism from the Cambridge college masters (John Gielgud and Lindsay Anderson). In their meeting with Abrahams, the Cambridge masters allege it is ungentlemanly for an amateur to "play the tradesman" by employing a professional coach. Abrahams realizes this is a cover for their anti-Semitism and class entitlement, and dismisses their concern.Meanwhile, when Liddell accidentally misses a church prayer meeting because of his running, his sister Jennie upbraids him and accuses him of no longer caring about God. But Eric tells her that though he intends to eventually return to the China mission, he feels divinely inspired when running, and that not to run would be to dishonor God: "I believe that God made me for a purpose. But He also made me fast, and when I run, I feel His pleasure."The two athletes, after over a year of training and racing, are accepted to represent Great Britain in the 1924 Summer Olympics in Paris, France. Also accepted are Abrahams' Cambridge buddies, Lord Andrew Lindsay (Nigel Havers), Aubrey Montague (Nicholas Farrell), and Henry Stallard (Daniel Gerroll) whom join the UK team.While boarding the boat to Paris for the Olympics, Liddell learns from the newspapers that the event for his 100 meter race will be on a Sunday. Liddell refuses to run the race despite strong pressure from the Prince of Wales (David Yelland) as well as the head of the British Olympic committee, Lord Cadogan (Patrick Magee) because Liddell's Christian convictions prevent him from running on the Christian Sabbath (Sunday).Hope appears in the form of Liddell's teammate Lord Andrew Lindsay. Having already won a silver medal in the 400 meter hurdles, Lindsay proposes to yield his place in the 400 meter race on the following Tuesday to Liddell. Liddell gratefully agrees. His religious convictions in the face of national athletic pride make headlines around the world.Liddell delivers a sermon at the Paris Church of Scotland that Sunday, and quotes from Isaiah 40, verse 31:"But they that wait upon the LORD shall renew their strength; they shall mount up with wings as eagles; they shall run, and be not weary; and they shall walk, and not faint."Meanwhile, Abrahams is badly beaten by the heavily favored and more experienced United States runner Charles Paddock (Dennis Christopher) in the 200 meter race who wins the gold medal, while Abrahams takes a second place silver medal. Abrahams knows that his last chance for a gold medal will be the 100 meter run. He competes in the 100 meter sprint and wins, beating Paddock and the rest of the Americans.On Tuesday, just before Liddell's race, the American coach remarks to his runners that Liddell has little chance 
 Question: Who accidentally misses a church prayer meeting?

liddell.