In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

 H2O2 was found to stimulate Ins - 1 , 4 , 5 - P3 production in a tyrosine kinase - dependent manner and to induce calcium signals that were greatly augmented by vanadate .
tyrosine kinase

 A nonpeptidyl small molecule SB 247464 , capable of activating granulocyte - colony - stimulating factor ( G - CSF ) signal transduction pathways , was identified in a high - throughput assay in cultured cells .
G - CSF

 Stable adhesion of leukocytes to glucose - treated as well as to IL - 1beta - stimulated endothelial cells was preceded by short interaction of leukocytes with the endothelial surface .

IL - 1beta