In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

Q:  However , most effector CD8 + T cells recovered after exposure to Ag do not produce sufficient IL - 2 to sustain growth , and depend on CD4 + T helper cells for this obligate growth factor .

A: IL - 2
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Q:  Stimulation of T lymphocytes results in a rapid increase in intracellular calcium concentration ( [ Ca2 + ] i ) that parallels the activation of Ca2 + - calmodulin - dependent protein kinase IV ( CaMKIV ) , a nuclear enzyme that can phosphorylate and activate the cyclic adenosine monophosphate ( cAMP ) response element - binding protein ( CREB ) .

A: nuclear enzyme
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Q:  We review the contribution of several transcription factors to the control of macrophage development

A:
transcription factors
****