Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Input: Consider Input: Context: The circumsporozoite protein (CS protein) on the malaria parasites in mosquitoes plays an important role in sporogony in mosquitoes. The RTS,S/AS01 malaria vaccine candidate, which has shown significant efficacy against clinical malaria in a large Phase 3 trial, targets the Plasmodium falciparum CS protein, but the ability of serum from vaccinated individuals to inhibit sporogony in mosquitoes has not been evaluated. Previously a double-blind, randomized trial of RTS,S/AS01 vaccine, as compared with rabies vaccine, in five- to 17-month old children in Tanzania was conducted. In this study, polyclonal human antibodies were purified from the pools of sera taken one month after the third vaccination. IgGs were purified from four pools of sera from 25 RTS,S/AS01 vaccinated children each, and two pools of sera from 25 children vaccinated with rabies vaccine each. The ability of antibodies to inhibit P. falciparum oocyst formation and/or sporogony in the mosquito host was evaluated by a standard membrane-feeding assay. The test antibodies were fed on day 0 (at the same time as the gametocyte feed), or on days 3 or 6 (serial-feed experiments). The oocyst and sporozoite counts were performed on days 8 and 16, respectively. In addition, two human anti-CS monoclonal antibodies (mAb) and a control mAb were also evaluated. Polyclonal anti-CS IgG preparations from RTS,S-vaccinated children tested at concentrations of 149-210 ELISA units (EU)/ml did not show significant inhibition in oocyst and sporozoite formation when the antibodies were fed with gametocytes at the same time, or later (serial-feed experiments). Similarly, anti-CS mAbs tested at 6,421 or 7,122 EU/ml did not show reduction in oocyst and sporozoite formation. This study does not support the concept that anti-CS antibodies induced by the RTS,S/AS01 vaccines in humans noticeably reduce malaria transmission by blocking P. falciparum sporozoite development or salivary gland invasion in mosquitoes when taken up during feeding. 
 Question: RTS S AS01 vaccine was developed to prevent which disease?

Output: malaria


Input: Consider Input: Context: Stress is the force applied to an object. In geology, stress is the force per unit area that is placed on a rock. Four types of stresses act on materials. A deeply buried rock is pushed down by the weight of all the material above it. Since the rock cannot move, it cannot deform. This is called confining stress. Compression squeezes rocks together, causing rocks to fold or fracture (break) (Figure 1.1). Compression is the most common stress at convergent plate boundaries. Stress caused these rocks to fracture. Rocks that are pulled apart are under tension. Rocks under tension lengthen or break apart. Tension is the major type of stress at divergent plate boundaries. When forces are parallel but moving in opposite directions, the stress is called shear (Figure 1.2). Shear stress is the most common stress at transform plate boundaries. Shearing in rocks. The white quartz vein has been elongated by shear. When stress causes a material to change shape, it has undergone strain or deformation. Deformed rocks are common in geologically active areas. A rocks response to stress depends on the rock type, the surrounding temperature, the pressure conditions the rock is under, the length of time the rock is under stress, and the type of stress. Rocks have three possible responses to increasing stress (illustrated in Figure 1.3): elastic deformation: the rock returns to its original shape when the stress is removed. plastic deformation: the rock does not return to its original shape when the stress is removed. fracture: the rock breaks. Under what conditions do you think a rock is more likely to fracture? Is it more likely to break deep within Earths crust or at the surface? What if the stress applied is sharp rather than gradual? At the Earths surface, rocks usually break quite quickly, but deeper in the crust, where temperatures and pressures are higher, rocks are more likely to deform plastically. Sudden stress, such as a hit with a hammer, is more likely to make a rock break. Stress applied over time often leads to plastic deformation. Click image to the left or use the URL below. URL: 
 Question: rocks that are pulled apart are under

Output: tension


Input: Consider Input: Context: In the county, the population was spread out with 23.20% under the age of 18, 7.70% from 18 to 24, 27.00% from 25 to 44, 28.00% from 45 to 64, and 14.10% who were 65 years of age or older. The median age was 40 years. For every 100 females, there were 97.00 males. For every 100 females age 18 and over, there were 96.40 males. 
 Question: Which gender group is larger: females or males?


Output: females