Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: This procedure appears to be a simple, safe, and effective method for closure of a small conjunctival break.
Example Output: non-adverse drug event

Example Input: Paradoxical ventricular tachycardia and fibrillation after intravenous bretylium therapy.
Example Output: adverse drug event

Example Input: We report a case of generalized cutaneous sclerosis associated with muscle and oesophageal involvement in a patient exposed to herbicides containing bromocil, diuron and aminotriazole.
Example Output:
adverse drug event