Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Ex Input:
Context: In the Caucasus region of Russia, nearly 50 out of every 100,000 people live to celebrate their 100th birthday, and many don't stop at 100! By comparison, in America only 3 people in 100,000 reach 100. But these Russian old people aren't alone. The Pakistanis, who live high in the Himalaya Mountains, and the Ecuadorans of the Andes Mountains seem to share the secret of long life, too. These people remain healthy in body and spirit despite the passage of time. While many older persons in industrial societies become weak and ill in their 60s and 70s, some Caucasians aged 100 to 140, work in the fields beside their great-great-grandchildren. Even the idea of aging is foreign to them. When asked "at what age does youth end?"most of these old people had no answer. Several replied, "Well, perhaps at age 80." What accounts for this ability to survive to such old age, and to survive so well?First of all, hard physical work is a way of life for all of these long-lived people. They begin their long days of physical labor as children and never seem to stop. For example, Mr . Rustam Mamedov is 142 years of age. His wife is 116 years old. They have been married for 90 years. Mr. Mamedov has no intention of retiring from his life as a farmer. "Why?What else would I do?"he asks. All these people get healthful rewards from the environment in which they work. They all come from mountainous regions. They live and work at elevations of 1,660 to 1,000 meters above sea level. The air has less oxygen and is pollution-free. This reduced-oxygen environment makes the heart and blood vessel system stronger. Another factor that may contribute to the good health of these people is their isolation. To a great extent, they are separated from the pressures and worries of industrial society. Inherited factors also play some role. Most of the longest-lived people had parents and grandparents who also reached very old ages. Good family genes may, therefore, be one factor in living longer. 
 Question: What is the main way of life for all of these long-lived people?

Ex Output:
hard physical work.


Ex Input:
Context: Facioscapulohumeral muscular dystrophy (FSHD) is one of the most prevalent adult muscular dystrophies. The common clinical signs usually appear during the second decade of life but when the first molecular dysregulations occur is still unknown. Our aim was to determine whether molecular dysregulations can be identified during FSHD fetal muscle development. We compared muscle biopsies derived from FSHD1 fetuses and the cells derived from some of these biopsies with biopsies and cells derived from control fetuses. We mainly focus on DUX4 isoform expression because the expression of DUX4 has been confirmed in both FSHD cells and biopsies by several laboratories. We measured DUX4 isoform expression by using qRT-PCR in fetal FSHD1 myotubes treated or not with an shRNA directed against DUX4 mRNA. We also analyzed DUX4 downstream target gene expression in myotubes and fetal or adult FSHD1 and control quadriceps biopsies. We show that both DUX4-FL isoforms are already expressed in FSHD1 myotubes. Interestingly, DUX4-FL expression level is much lower in trapezius than in quadriceps myotubes, which is confirmed by the level of expression of DUX4 downstream genes. We observed that TRIM43 and MBD3L2 are already overexpressed in FSHD1 fetal quadriceps biopsies, at similar levels to those observed in adult FSHD1 quadriceps biopsies. These results indicate that molecular markers of the disease are already expressed during fetal life, thus opening a new field of investigation for mechanisms leading to FSHD. 
 Question: Which disease is associated with the ectopic expression of the protein encoded by the gene DUX4?

Ex Output:
fshd


Ex Input:
Context: The water that comes out of our faucets is safe because it has gone through a series of treatment and purification processes to remove contaminants. Those of us who are fortunate enough to always be able to get clean water from a tap in our home may have trouble imagining life in a country that cannot afford the technology to treat and purify water. Many people in the world have no choice but to drink from the same polluted river where sewage is dumped. One- fifth of all people in the world, more than 1.1 billion people, do not have access to safe water for drinking, personal cleanliness, and domestic use. Unsafe drinking water carries many pathogens, or disease-causing biological agents such as infectious bacteria and parasites. Toxic chemicals and radiological hazards in water can also cause diseases. Waterborne disease caused by unsafe drinking water is the leading cause of death for children under the age of five in many nations and a cause of death and illness for many adults. About 88% of all diseases are caused by drinking unsafe water (Figure 1.1). Throughout the world, more than 14,000 people die every day from waterborne diseases, such as cholera, and many of the worlds hospital beds are occupied by patients suffering from a waterborne disease. Guinea worm is a serious problem in parts of Africa that is being eradicated. Learn what is being done to decrease the number of people suffering from this parasite at the video below. Click image to the left or use the URL below. URL: 
 Question: which of these is an example of a waterborne disease?

Ex Output:

cholera