In this task, you will be given a sentence. You need to reconize the name of the disorder or disease. Disease is a disorder of structure or function in a human, animal, or plant, especially one that produces specific symptoms or that affects a specific location and is not simply a direct result of physical injury. Although there might be several correct answers, you need to write one of them.

Q:  Skin fragility in most cases is due to mutations in the gene encoding type XVII collagen ( COL17A1 ) .

A: Skin fragility
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Q:  Liver biopsy is also used to establish the presence or absence of cirrhosis , which can affect prognosis and management .

A: cirrhosis
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Q:  The DMPK gene of severely affected myotonic dystrophy patients is hypermethylated proximal to the largely expanded CTG repeat .

A:
myotonic dystrophy
****