Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: Quetiapine-induced leucopenia and thrombocytopenia.

Output: adverse drug event


Input: Consider Input: Following intravenous hydration and administration of bicarbonate, the patients' condition resolved without permanent' sequelae.

Output: non-adverse drug event


Input: Consider Input: Histological improvement with lamivudine therapy for de novo hepatitis B occurring in an anti-HBs-positive child after bone marrow transplantation.


Output: non-adverse drug event