In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[EX Q]: Question: In disorders related to substance use, what is physical dependence? 
 Options:  <1> In a physical process of short duration. <2> In an intense sense of dissatisfaction for not being able to consume the substances. <3> In the action of consuming drugs producing a state of intoxication with psychoactive effect. <4> In a series of physical and psychic changes that take place after the administration of a substance. <5> In a state of physical adaptation manifested by intense physical disturbances when the administration of the drug is interrupted.
[EX A]: 5

[EX Q]: Question: Which of the following statements is true with respect to the alkaloid morphine ?: 
 Options:  <1> It is an isoquinoline alkaloid extracted from straw of Papaver somniferum. <2> It is a benzylisoquinol alkaloid extracted from latex of Papaver somniferum. <3> It is a tracheal alkaloid extracted from leaves of Papaver somniferum. <4> It is a quinolizidine alkaloid extracted from capsules of Papaver somniferum. <5> It is a pyrrolidinic alkaloid extracted from roots of Papaver somniferum.
[EX A]: 2

[EX Q]: Question: A rat pathogen that has fleas as vectors of transmission to humans is: 
 Options:  <1> Rickettsia rickettsii. <2> Yersinia pestis <3> Borrelia burgdorferi. <4> Ehrlichia ewingii. <5> Brucella abortus.
[EX A]:
2