In this task, find the most appropriate number to replace the blank (indicated with _ ) and express it in words.

[EX Q]: Skin cancer affects one in _ people in the United States over a lifetime.
[EX A]: six

[EX Q]: Water is the only substance on earth that exists naturally in _ states .
[EX A]: three

[EX Q]: Men are three to _ times more likely than women to be diagnosed with esophageal cancer.
[EX A]:
five