Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: Pneumocystis pneumonia should be considered in asthmatic patients taking methotrexate who present with fever, pulmonary infiltrates, and hypoxia.
Example Output: adverse drug event

Example Input: A neuroprotective and neuroregenerative treatment attempt with pyridoxine and pyridostigmine was initiated.
Example Output: non-adverse drug event

Example Input: Metipranolol associated granulomatous anterior uveitis: not so uncommon as thought.
Example Output:
adverse drug event