Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Following prompt recognition and diagnosis, intravenous thrombolytic therapy was administered 2 hours after symptom onset.
non-adverse drug event

Patients who develop these reactions whilst receiving GSTM can be successfully changed to aurothioglucose.
non-adverse drug event

OBJECTIVE: To describe a case of severe skin necrosis resulting from peripheral intravenous administration of low-dose vasopressin in a patient with catecholamine-resistant septic shock.

adverse drug event