Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

[Q]: Question: Is the ribbon-associated protein C-terminal-binding protein 1 essential for the structure and function of retinal ribbon synapses?
Answer: Overall the results suggest that CtBP1 protein is not essential for the formation of functional ribbon synapses in the retina.
[A]: no


[Q]: Question: Is routine preoperative lymphoscintigraphy necessary prior to sentinel node biopsy for breast cancer?
Answer: Preoperative lymphoscintigraphy adds little additional information to intraoperative lymphatic mapping, and its routine use is not justified.
[A]: no


[Q]: Question: Does absolute lymphocyte count with extreme hyperleukocytosis have a prognostic impact in chronic lymphocytic leukemia?
Answer: Although our results do not confirm that high initial levels of WBC are independently associated with shorter survival in CLL, the clinical course in these cases appears to be aggressive and conventional prognostic factors are not valid in this patient sub-group.
[A]:
no