Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Is neutrophil-lymphocyte ratio a reliable predictive marker for early-stage diabetic nephropathy?
Answer: Increased NLR was significantly associated with DN, and high NLR values may be a reliable predictive marker of early-stage DN.
yes

Question: Does the Drosophila Chmp1 protein determine wing cell fate through regulation of epidermal growth factor receptor signaling?
Answer: Drosophila Chmp1 negatively regulates DER signaling, likely through its role in MVB formation. Loss of Chmp1 activity in the Drosophila wing induces a cell fate change from intervein to vein that should provide a useful tool for future studies of ESCRT protein activity.
yes

Question: Does daily acclimation handling affect hippocampal long-term potentiation or cause chronic sleep deprivation in mice?
Answer: It is possible to handle mice daily to accustom them to the researcher without causing alterations in sleep, stress, or synaptic plasticity in the hippocampus. Therefore, effects of acclimation handling cannot explain the impairments in signaling mechanisms, synaptic plasticity, and memory that result from brief sleep deprivation.

no