instruction:
Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.
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Paragraph: The idea that the domestic dog descended from the grey wolf was originally established in 1993 using comparisons of wolf and dog mitochondrial DNA. This investigation showed that no other living animal was more closely related to the domestic dog than the grey wolf: “The domestic dog is an extremely close relative of the grey wolf, differing from it by at most 0.2% of [mitochondrial DNA].” Mitochondrial DNA is passed down by the mother (without any genetic contribution from the father) and changes only through random mutations that occur from generation to generation. Scientists use this much smaller and separate DNA sequence to estimate when populations of animals first diverged and to estimate the evolutionary relationships between organisms. By the mid-2000s, new technology allowed scientists to map the much longer DNA sequence found on the chromosomes of wolves and dogs — the genes that actually code for physical traits and behaviors. These studies demonstrated a 99.9% similarity (technically 99.96%) between dog and grey wolf, as covered in a 2007 review paper on the topic: In general, the domestic dog is an extremely close relative of the grey wolf, from which it differs by only ~0.04% in nuclear coding-DNA sequence, and no dog [mitochondrial DNA] sequences have been found that show closer kinship to other canid species. This similarity is so profound that hybridization often occurs between dogs and wolves. By the biological definition of species, this would mean that the domestic dog is a subspecies of the grey wolf (canis lupus familiaris). There remains some debate, however, as to what the appropriate classification for the domestic dog would be, with some arguing that the domestic dog should be its own distinct species (canis familiaris). Claim: Dogs and wolves are genetically 99.9% identical.
answer:
These advances in genetic analysis have allowed scientists as well to pin down the probable timing of the split between these two canid lineages. A study published in 2015, which compared the whole genome sequence of dogs to a 35,000 year old Siberian wolf specimen, suggested the split likely occurred between 27,000 and 40,000 years ago, and that domestic dogs are likely themselves the descendants of a now extinct descendant of grey wolves.


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Paragraph: "India has reported 471 cases of the coronavirus but health experts have warned that a big jump could be imminent, which would overwhelm the underfunded and crumbling public health infrastructure. On Monday, India confirmed two more deaths, bringing the total to nine. One was a 54-year-old man with no history of foreign travel, suggesting the start of community transmission of the virus, officials said. Streets were deserted in the national capital New Delhi and offices shut at the start of a lockdown to run till the end of the month. The government ordered commercial airlines to shut down domestic operations from midnight on Tuesday on top of a ban on international flights to try and contain the coronavirus. About 144 million people traveled on domestic flights last year. Rail travel, the lifeline of India, has already been suspended after thousands of people, mostly migrant workers, swarmed train stations to go home as businesses shut down and jobs dried up. Prime Minister Narendra Modi said many Indians were not taking the lockdown seriously. “Please save yourself, save your family, follow the instructions seriously,” he said on Twitter. The chief minister of the western state of Maharashtra, which has had the highest number of cases in India, ordered a curfew from Tuesday to force people indoors. “Despite multiple requests, people are not following rules. This compelled the government to impose the curfew,” Uddhav Thackeray said. The country’s main stock exchange located in Mumbai, the capital of Maharashtra, will however remain open, an official said. On Monday night, the Indian government said 30 states and union territories, or 548 districts, were under “complete lockdown.”   Newspapers canceled print runs in Mumbai after vendors refused to distribute them due to worries about the coronavirus, which emerged in China late last year and has spread around the world. Globally, cases exceed 325,000 with deaths topping 14,000. The Pakistani army said on Monday night it would help to impose nationwide restrictions to contain the spread of the coronavirus following a request from the government. Major General Babar Iftikhar said schools, malls, restaurants, cinemas, marriage halls, swimming pools and markets would be shut as of Monday with only eateries, pharmaceutical companies and medical stores allowed to remain open. Prime Minister Imran Khan had previously said he opposed such stringent measures because of the economic consequences for the poor. A spokesman did not immediately respond to a request for comment. Nepal ordered all land border crossings with India and China shut until March 29, saying thousands of people, most of them Nepali migrant workers, had crossed into Nepal in recent days from India, believing their homeland to be safer. Nepal reported its second case of the coronavirus on Monday, a citizen who had recently returned from France. “The closing of the border crossings is meant to ensure that no one infected with the virus crosses over to Nepal from India and China,” said Surya Thapa, an aide to Prime Minister K.P. Sharma Oli. Confirmed COVID-19 cases in South Asia:  *Pakistan   -   875  *India      -   471  *Sri Lanka  -    91   *Afghanistan  -    42  *Bangladesh  -    33  *Maldives     -    13   *Nepal       -     2  *Bhutan      -     2    ———————————-  TOTAL         - 1,529  https://www.mohfw.gov.in  hpb.health.gov.lk/en  http://covid.gov.pk  covid19.health.gov.mv/en" Claim: India shuts down flights, big cities as coronavirus toll rises in region.
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India on Monday announced a halt to domestic flights and said the majority of the country was under complete lockdown to stop the spread of coronavirus as the number of people dying of the disease ticked up across densely populated South Asia.


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Paragraph: The wealthy family in a motion on Monday argued that Massachusetts Attorney General Maura Healey’s lawsuit mischaracterized internal records to create the “false impression” they personally directed privately-held Purdue’s marketing of painkillers. Her lawsuit, filed in June in Suffolk County Superior Court and revised earlier this year to include new allegations, was the first by a state to try to hold Sackler family members personally responsible for contributing to the opioid epidemic. The case is among roughly 2,000 lawsuits filed mostly by state and local governments seeking to hold Purdue and other pharmaceutical companies responsible for the opioid crisis. Opioids were involved in a record 47,600 overdose deaths in 2017 in the United States, according to the U.S. Centers for Disease Control and Prevention. Healey’s complaint cites records to argue that family members, including Purdue’s former President Richard Sackler, personally directed deceptive opioid marketing while making $4.2 billion from Purdue from 2008 to 2016. They did so even after Purdue and three executives in 2007 pleaded guilty to federal charges related to the misbranding of OxyContin and agreed to pay a total of $634.5 million in penalties, the lawsuit said. But in their motion, the Sacklers said nothing in the complaint supports allegations they personally took part in efforts to mislead doctors and the public about the benefits and addictive risks of opioids. They said their role was limited to that of typical corporate board members who participated in “routine” votes to ratify the management’s staffing and budget proposals. “Not a single document shows an individual director engaging in any unlawful conduct regarding the sale of prescription opioids or ordering anyone else to do so,” the Sacklers’ lawyers wrote. Healey, in a statement, called the motion “an attempt to avoid accountability.”  At least 35 states have cases pending against Purdue. Four  have also named Sackler family members as defendants, including Richard Sackler, Theresa Sackler and Mortimer D.A. Sackler. Last week, Purdue reached its first settlement in the recent wave of lawsuits, agreeing with the Sacklers to a $270 million deal with Oklahoma’s attorney general. Oklahoma’s lawsuit did not name Sacklers as defendants. Purdue had been exploring filing for bankruptcy before the accord’s announcement, Reuters reported in early March. Claim: Purdue's Sackler family fights 'inflammatory' Massachusetts opioid case.
answer:

Members of the Sackler family behind OxyContin maker Purdue Pharma LP have asked a judge to toss a lawsuit by the Massachusetts attorney general that claims they helped fuel the U.S. opioid epidemic, arguing it contains “misleading and inflammatory allegations.”