Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[EX Q]: The aim of this study was to elucidate the role of lysyl oxidase (LOX) and lysyl oxidase like (LOXL) 2 in pathologic wound healing after glaucoma surgery. We therefore investigated the expression of LOX and LOXL2 and evaluated the therapeutic potential of anti-LOX (GS-639556, formerly M64) and anti-LOXL2 (GS-607601, formerly AB0023) antibodies in a rabbit model of glaucoma trabeculectomy. Ocular expression of LOX and LOXL2 was investigated by immunohistologic staining at different time points after trabeculectomy. Treatment with GS-639556 or GS-607601 was initiated in rabbits immediately after trabeculectomy by giving both intracameral and subconjunctival injections. Thereafter, the antibodies were given twice a week subconjunctivally until day 30 after surgery (day of euthanization). Treatment outcome was studied by clinical investigation of the bleb and by immunohistochemical analysis of angiogenesis, inflammation, and collagen deposition. LOX and LOXL2 were both upregulated in Tenon's capsule and the conjunctiva after glaucoma surgery. Repeated administration of LOX- or LOXL2-targeting monoclonal antibodies increased bleb area and bleb survival. Analyses of immunohistologic stainings showed that both antibodies significantly decreased fibrosis, whereas the anti-LOXL2 antibody also significantly reduced blood vessel density and inflammation. Targeting LOXL2 with an inhibitory monoclonal antibody (GS-607601) reduced pathologic angiogenesis, inflammation, and fibrosis. These results suggest that LOXL2 could be an appealing target for treatment of scar formation after glaucoma surgery, and point to the potential therapeutic benefits of simtuzumab, a humanized monoclonal antibody derived from GS-607601.
[EX A]: What is the drug target for Simtuzumab?

[EX Q]: Michael Jackson is one of the world's best singers. Michael Jackson was born in the middle west of the city of Gary, Indiana, in 1958. He began singing with his four brothers. They called the group "The Jackson Five". The group became very popular after appearing on a television program. They started singing in 1965, and became popular soon. In 1970 the group made their first record with the name of "I Want You Back". It was very popular. One of their hit records was "Never Say Goodbye". Michael was good at dancing as well as singing, such as his dance moves and moon walking. He was asked to act in a film in 1978 for the first time, and in the same year he made a record on his own, which sold eight million _ all over the world. Michael nearly didn't go out because he was too famous. Once his fans went off in a faint when they saw him at the concert. No one can do it by now. He lived in a large house and kept lots of animals. He never ate meat. He often raised money for Charity. This made him win the Guinness World Records in 2006. He died on June 25th, 2009, but he would live in our heart forever.
[EX A]: What's the name of their first record?

[EX Q]: Some people bring out the best in you in a way that you might never have fully realized on your own. My mom was one of those people. My father died when I was nine months old, making my mom a single mother at the age of eighteen. While I was growing up, we lived a very hard life. We had little money, but my mom gave me a lot of love. Each night, she sat me on her lap and spoke the words that would change my life, "Kemmons, you are certain to be a great man and you can do anything in life if you work hard enough to get it." At fourteen, I was hit by a car and the doctors said I would never walk again. Every day,my mother spoke to me in her gentle,loving voice, telling me that no matter what those doctors said, I would walk again if I want to badly enough. She drove that message so deep into my heart that I finally believed her.A year I returned to school--walking on my own ! When the Great Depression hit, my mom lost her job. Then I left school to support the both of us. At that moment, I was determined never to be poor again. Over the years, I experienced various levels of business success. But the real turning point occurred on a vacation I took with my wife and five kids in1951. I was dissatisfied with the second-class hotels available for families and was angry that they charged an extra $2 for each child. That was too expensive for the average American family. I told my wife that I was going to open a motel for families that would never charge extra for children. There were plenty of doubters at that time. Not surprisingly, Mom was one of my strongest supporters. She worked behind the desk and even designed the room style. As in any business,we experienced a lot of challenges. But with my mother's words deeply rooted in my soul, I never doubted we would succeed.Fifteen years later,we had the largest hotel system in the world--Holiday Inn. In 1979 my company had 1759 inns in more than fifty countries with an income of $1billion a year. You may not have started out life in the best situations. But if you can find a task in life worth working for and believe in yourself, nothing can stop you.
[EX A]:
According to the author, who played the most role in making him walk back to school again?