Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Example Input: Paragraph: Chief Executive Andrew Witty said on Wednesday there were still “intriguing” opportunities for its heart drug darapladib and MAGE-A3 therapeutic cancer vaccine. Many analysts stripped out forecasts for darapladib, which is designed to prevent heart attacks and strokes in a completely different way from cholesterol-lowering drugs, after it failed to reduce risks in the first of two big final Phase III trials in November. GSK, however, is continuing to investigate the drug’s role in coronary heart disease and Witty told analysts in a call following full-year results that further data on the approach would be presented at a medical meeting next month. He was also upbeat about prospects for the MAGE-A3 cancer vaccine in other tumor settings, despite initial negative results in melanoma in September. Unlike traditional preventative vaccines, MAGE-A3 is designed for people with established disease, helping their immune systems to prevent the return of tumors after surgery. In fact the head of Britain’s biggest drugmaker said both darapladib and MAGE-3 were among the most promising drugs in the company’s pipeline. He also highlighted a new triple combination respiratory drug, a long-acting integrase inhibitor for HIV and a drug for pre-term labor, all of which could start final Phase III clinical testing this year or next. Claim: GSK upbeat on heart drug, cancer vaccine despite setbacks.
Example Output: Two high-risk bets by GlaxoSmithKline on new ways to fight heart disease and cancer were dealt a double blow last year by dud clinical trials - but the company remains hopeful about both projects.

Example Input: Paragraph: The tougher regulations, set by the United Nations shipping agency, the International Maritime Organization (IMO), come into force on Jan 1. Costs will rise for ships towards the end of this year and there will be a knock on effect for trucks and other transporters that move goods around the world. For shipping companies it is the biggest shakeup in decades and adds to the pressures of an economic slowdown and the threat of an escalating trade war between the United States and China. While consumers are not expected to pay more for goods, higher transport bills and disruption to company deliveries could further dent economic growth. Ship owners must cut sulphur emissions to 0.5% from 3.5%. They can do this by using low-sulphur fuel, installing exhaust gas cleaning systems or opting for other, more expensive, clean fuels such as liquefied natural gas or traveling more slowly. Jeff Child, president of Berkshire Hathaway’s RC Willey Home Furnishings, moved the delivery of about 450 containers from September and October to July and August. He wants to avoid any disruption in the peak fourth quarter as ships prepare for the changes, including refitting equipment. “We just don’t want to get caught in a situation where it affects our inventory,” he told Reuters. Analysts say the container industry, which transports consumer goods such as sofas, designer clothes and bananas, will be one of the worst hit with extra costs of about $10 billion. The world’s two biggest container shipping lines - Denmark’s Maersk and Swiss headquartered MSC - say they face annual extra costs of over $2 billion each. Twenty-five logistics company executives told Reuters they would pass along any IMO-related costs, such as ship upgrades or more expensive fuel, to customers. “The sulphur cap will further put pressure on ocean freight rates and we... will have to pass those costs on to remain competitive,” Peder Winther, global head of ocean freight with Swiss transportation company Panalpina Group said. Economists say manufacturers are expected to absorb their part of the cost and are unlikely to raise the price of consumer goods, but the hit to companies could be a drag on the world economy. A Nestle S.A. spokesperson said the food group was talking to transport companies about “fuel adjustment methodology” to reflect the impact of the new rules. “Higher fuel prices would result in higher transport costs,” said Peter Nagle, an economist with the World Bank’s Development Prospects Group. “This would have the potential to lead to slower economic growth and trade.”   Trucking companies will also suffer. The IMO rules do not apply to them but they will face new competition from ships for lower sulfur fuel. This is expected to push up the price of diesel fuel for trucks by as much as 100 percent. Small to mid-sized truckers may find it tough as they lack the clout to negotiate fuel deals or to recoup the costs. “I’m at the whim of the market. All I can do is let the customers know what’s going on,” said Mike Baicher, president and chief executive of New Jersey based West End Express, which runs 90 trucks in New York, New Jersey and along the East Coast. “There is only so much that the trucking company can absorb.”   In a letter sent to top U.S. government officials including National Security Advisor John Bolton, transport associations including trucking groups said there was consensus that U.S. transport industries would be “negatively affected by IMO 2020 pricing pressure”. It said there could be market disruptions. “There’s a storm approaching but we don’t know how bad the storm is going to be,” said Glen Kedzie, energy and environmental counsel for the American Trucking Associations. Shipping and freight forwarding companies, who offer a service overseeing the delivery of goods from beginning to end, expect to feel more cost pressure. Bart de Vries, chief operating officer for air & sea with U.S. headquartered Hellmann Worldwide Logistics, expects to pay more for services as shipping companies pass along the costs. Some companies may overhaul their business plans. “It will undoubtedly force many exporters and importers to review their sourcing strategies and vendors,” said Cas Pouderoyen, senior vice president of ocean freight with global logistics company Agility         Richard Fattal, co-founder of digital freight forwarder and logistics provider Zencargo, said there could be as much as a 10 to 20% rise in overall operating costs next year. Allen Clifford, a U.S.-based executive vice president with MSC, said at a recent forum in California that his company was facing huge expenses. “Who’s going to pay for it? You’re going to pay for it. Because I’m tired of paying for it,” he told industry executives, and port and customs officials. Claim: Education Week rates Ohio schools in the top five in the nation.
Example Output: U.S. furniture company RC Willey Home Furnishings is so concerned that new global clean air rules will cause transport disruption that it brought forward the shipment of arm chairs and sofas from China by two months.

Example Input: Paragraph: Publishing a study that found risk score tools are only around 46 percent accurate on how likely psychopathic convicts are to kill, rape or assault again, they said probation officers and judges should set little or no store by such tests. They warned that clinicians carrying out such classifications must be aware of their severe limitations, and make sure prisoners undergo comprehensive psychiatric diagnosis before any risks assessment is made. “If you apply these (tests) to somebody who is a psychopath, they’re utterly useless, you might as well toss a coin,” said Jeremy Coid, director of the forensic psychiatry research unit at Queen Mary University of London who led the study. “They will not predict accurately at all,” he told reporters at a briefing in London about his findings. Coid and other forensic psychiatrists say the findings - which also showed the tools perform only moderately well in prisoners with disorders like schizophrenia, depression, drug and alcohol dependence - could have major implications for risk assessment in criminal justice systems. “There are increasing expectations of public protection from violent behavior, and psychiatrists can be seriously criticized if they make wrong decisions,” he said. Seena Fazel, a consultant forensic psychiatrist at Britain’s University of Oxford, said the reliability of the tests’ predictive ability was so low that it might be best not to use them at all - and warned that at the very least, their results should only be noted by parole boards, rather than acted upon. “If you’re going to use these instruments, be aware of their strengths and limitations,” he told reporters. The estimated prevalence of adult psychopathy in the general population is around 1 percent, but that rises to between 15 percent and 25 percent among men in prison. Coid, whose study was published in the British Journal of Psychiatry, analyzed data from 1,396 male prisoners in England and Wales who were interviewed between six and 12 months before their release. All the men were serving sentences of two or more years for a sexual or violent offences. The prisoners were assessed for personality disorders, symptoms of schizophrenia, depression and drug and alcohol dependence, as well as being measured for psychopathy on a reputable scale known as Hare Psychopathy Check List. After their release, data on their re-offending rates was added to the study, and showed that among three different re-offending risk assessment tools used before their release, the accuracy among psychopaths was below 50 percent. While the tools were more accurate in predictions for prisoners with no mental health disorders - at around 75 percent accuracy - they were only around 60 percent right when it came to prisoners diagnosed with schizophrenia and depression. For prisoners with anti-social personality disorders the predictive value of the tests ranged from poor to little more than chance, with an average 53.2 percent predictive accuracy. And for the 70 prisoners rated as psychopathic, none of the tests was statistically better than chance. Coid said the results suggest it is time to question the expectations put on psychiatrists and psychologists asked to forecast future behavior of offenders, and to consider what can happen to their reputations if predictions are wrong. “The easy solution is to be highly restrictive on who is released, and be risk averse. However, even for serious offenders, most will be released at some stage and someone has to carry out a risk assessment,” he said. “We need to prioritize the development of new assessment tools for these hard-to-predict groups.” Claim: Predicting violence in psychopaths is 'no more than chance'.
Example Output:
Assessment tools used to predict how likely a psychopathic prisoner is to re-offend if freed from jail are “utterly useless” and parole boards might just as well flip a coin when deciding such risks, psychiatrists said on Tuesday.