Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Q: Many different cellular pathways have evolved to protect the genome from the deleterious effects of DNA damage that result from exposure to chemical and physical agents. Among these is a process called transcription-coupled repair (TCR) that catalyzes the removal of DNA lesions from the transcribed strand of expressed genes, often resulting in a preferential bias of damage clearance from this strand relative to its non-transcribed counterpart. Lesions subject to this type of repair include cyclobutane pyrimidine dimers that are normally repaired by nucleotide excision repair (NER) and thymine glycols (TGs) that are removed primarily by base excision repair (BER). While the mechanism underlying TCR is not completely clear, it is known that its facilitation requires proteins used by other repair pathways like NER. It is also believed that the signal for TCR is the stalled RNA polymerase that results when DNA damage prevents its translocation during transcription elongation. While there is a clear role for some NER proteins in TCR, the involvement of BER proteins is less clear. To explore this further, we studied the removal of 7-methylguanine (7MeG) and 3-methyladenine (3MeA) from the dihydrofolate reductase (dhfr) gene of murine cell lines that vary in their repair phenotypes. 7MeG and 3MeA constitute the two principal N-methylpurines formed in DNA following exposure to methylating agents. In mammalian cells, alkyladenine DNA alkyladenine glycosylase (Aag) is the major enzyme required for the repair of these lesions via BER, and their removal from the total genome is quite rapid. There is no observable TCR of these lesions in specific genes in DNA repair proficient cells; however, it is possible that the rapid repair of these adducts by BER masks any TCR. The repair of 3MeA and 7MeG was examined in cells lacking Aag, NER, or both Aag and NER to determine if rapid overall repair masks TCR. The results show that both 3MeA and 7MeG are removed without strand bias from the dhfr gene of BER deficient (Aag deficient) and NER deficient murine cell lines. Furthermore, repair of 3MeA in this region is highly dependent on Aag, but repair of 7MeG is equally efficient in the repair proficient, BER deficient, and NER deficient cell lines. Strikingly, in the absence of both BER and NER, neither 7MeG nor 3MeA is repaired. These results demonstrate that NER, but not TCR, contributes to the repair of 7MeG, and to a lesser extent 3MeA.

A: Which gene strand is targeted by transcription-coupled repair (TCR)?
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Q: Somewhere in harbourside Sydney, Australia, a family lives within a high-rise apartment building where the mother is preparing a meal and listening to the radio. Her fourteen year old daughter (Jenny Agutter) and six year old son (Luc Roeg) swim in the building's pool overlooking a view of the ocean while their father (John Meillon), deep in troubled thought, watches them from their balcony.One day, the father takes his children, still in their school uniforms, on a picnic into the Outback. He parks the car and reads while his daughter sets up a blanket with their lunch. Her brother plays nearby with his water gun and toy soldiers. Suddenly, and for reasons unclear to his children, the father announces it is time to go and brandishes a gun, firing several shots at them. The boy thinks it all to be a game but his sister understands the danger and shields her brother as they run from their mad father. She watches in horror as her father returns to the car and sets it on fire before seating himself within and putting a bullet into his head. Quickly, and keeping her brother's eyes averted, the girl retrieves their radio, a scarf, and what food she can carry before setting off into the wilderness with her brother.The siblings walk for hours under the hot sun, calmed by irrelevant radio broadcasts, and walking past a host of wild creatures. Come nightfall, they make a crude camp for themselves, much to the boy's delight. In the morning, the girl leads them up a rocky hillside where she hopes to find some bearings. However, she can see nothing but a broad spanse of wilderness. When they finish their lemonade, the girl opens a can of vegetables from which they drink the juice. Recalling an uncle's story of military training, the girl suggests they eat salt to retain water and surmises to her brother that they may spend some time in the desert. She remains stoic, but wary, while her brother is blissfully unaware of their situation, remaining entertained by the radio and his toys. Eventually, after becoming filthy and tired, they come upon a lone tree standing over a pool of water where parakeets flock and feast on fallen fruit. The boy puts on in his mouth and proclaims that it 'tastes lovely'. They wash in the water and the girl scolds her brother to take care of his clothes so they will last. When he asks if they are lost, the girl replies that they are not, trying to remain chipper. They sleep to the sounds of the radio as night animals stir around them.In the morning, the girl wakes to find that their water hole has dried up and the fruit has either been eaten or spoiled. The girl decides to remain where they are, hoping that the water will return. As they nap in the hot sun, the boy spots an aborigine youth (David Gulpilil) pursuing an animal for food. They make contact and the children attempt to communicate with the aborigine boy. However, he does not understand their language and merely stares at them with curiosity. The girl repeats their need for water but the word is incomprehensible to the aborigine. When her brother mimics drinking, the aborigine understands and shows them how to dig for water using a hollow tube to drink through. Assuming that he will lead them to civilization, the siblings accompany the aborigine, unaware that he is on a 'walkabout', a coming-of-age journey that every male aborigine youth must take alone in order to be initiated as an adult in his tribe.As they travel the Outback, the aborigine kills and harvests food for them, giving them all plenty to eat and drink. The move from the desert to greener pastures and forests where wildlife becomes plentiful. When the boy becomes sunburnt from going shirtless, the aborigine rubs pig fat on his back to alleviate the burn. While communication between them remains limited, the trio share food and play together, though cultural differences are evident; the boy attempts to share his toy soldiers with the aborigine, but he finds no use for them and tosses

A: What does the Aboriginal boy hunt down ?
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Q: IDW Publishing is an American publisher of comic books, graphic novels, art books and comic strip collections.

A:
The product of IDW Publishing is what?
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