TASK DEFINITION: In this task, you are given the abstract of a research paper. Your task is to generate a summary of this abstract. Your summary should not be very short, but it's better if it's not more than 30 words.
PROBLEM: We develop a stochastic whole-brain and body simulator of the nematode roundworm Caenorhabditis elegans (C. elegans) and show that it is sufficiently regularizing to allow imputation of latent membrane potentials from partial calcium fluorescence imaging observations. This is the first attempt we know of to ``complete the circle,'' where an anatomically grounded whole-connectome simulator is used to impute a time-varying ``brain'' state at single-cell fidelity from covariates that are measurable in practice.   Using state of the art Bayesian machine learning methods to condition on readily obtainable data, our method paves the way for neuroscientists to recover interpretable connectome-wide state representations, automatically estimate physiologically relevant parameter values from data, and perform simulations investigating intelligent lifeforms in silico.

SOLUTION: We develop a whole-connectome and body simulator for C. elegans and demonstrate joint state-space and parameter inference in the simulator.

PROBLEM: High performance of deep learning models typically comes at cost of considerable model size and computation time. These factors limit applicability for deployment on memory and battery constraint devices such as mobile phones or embedded systems. In this work we propose a novel pruning technique that eliminates entire filters and neurons according to their relative L1-norm as compared to the rest of the network, yielding more compression and decreased redundancy in the parameters. The resulting network is non-sparse, however, much more compact and requires no special infrastructure for its deployment. We prove the viability of our method by achieving 97.4%, 47.8% and 53% compression of LeNet-5, ResNet-56 and ResNet-110 respectively, exceeding state-of-the-art compression results reported on ResNet without losing any performance compared to the baseline. Our approach does not only exhibit good performance, but is also easy to implement on many architectures.

SOLUTION: We propose a novel structured class-blind pruning technique to produce highly compressed neural networks.

PROBLEM: The practical usage of reinforcement learning agents is often bottlenecked by the duration of training time. To accelerate training, practitioners often turn to distributed reinforcement learning architectures to parallelize and accelerate the training process. However, modern methods for scalable reinforcement learning (RL) often tradeoff between the throughput of samples that an RL agent can learn from (sample throughput) and the quality of learning from each sample (sample efficiency). In these scalable RL architectures, as one increases sample throughput (i.e. increasing parallelization in IMPALA (Espeholt et al., 2018)), sample efficiency drops significantly. To address this, we propose a new distributed reinforcement learning algorithm, IMPACT. IMPACT extends PPO with three changes: a target network for stabilizing the surrogate objective, a circular buffer, and truncated importance sampling. In discrete action-space environments, we show that IMPACT attains higher reward and, simultaneously, achieves up to 30% decrease in training wall-time than that of IMPALA. For continuous control environments, IMPACT trains faster than existing scalable agents while preserving the sample efficiency of synchronous PPO.

SOLUTION:
IMPACT helps RL agents train faster by decreasing training wall-clock time and increasing sample efficiency simultaneously.