Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
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Question: Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a sensory-motor neurological disorder with a circadian component. RLS is characterized by uncomfortable sensations in the extremities, generally at night or during sleep, which often leads to an uncontrollable urge to move them for relief. Recently, genomic studies identified single-nucleotide polymorphisms in BTBD9, along with three other genes, as being associated with a higher risk of RLS. Little is known about the function of BTBD9 or its potential role in the pathophysiology of RLS. We therefore examined a line of Btbd9 mutant mice we recently generated for phenotypes similar to symptoms found in RLS patients. We observed that the Btbd9 mutant mice had motor restlessness, sensory alterations likely limited to the rest phase, and decreased sleep and increased wake times during the rest phase. Additionally, the Btbd9 mutant mice had altered serum iron levels and monoamine neurotransmitter systems. Furthermore, the sensory alterations in the Btbd9 mutant mice were relieved using ropinirole, a dopaminergic agonist widely used for RLS treatment. These results, taken together, suggest that the Btbd9 mutant mice model several characteristics similar to RLS and would therefore be the first genotypic mouse model of RLS. Furthermore, our data provide further evidence that BTBD9 is involved in RLS, and future studies of the Btbd9 mutant mice will help shine light on its role in the pathophysiology of RLS. Finally, our data argue for the utility of Btbd9 mutant mice to discover and screen novel therapeutics for RLS.

Answer: Willis-Ekbom disease is also known as?


Question: With the recent introduction of inhibitors of mammalian target of rapamycin (mTOR) in oncology, distinct cutaneous and oral adverse events have been identified. In fact, stomatitis and rash are documented as the most frequent and potentially dose-limiting side effects. Clinically, mTOR inhibitor-associated stomatitis (mIAS) more closely resembles aphthous stomatitis than oral mucositis due to conventional anticancer therapies. While most cases of mIAS are mild to moderate and self-limiting, more severe and persistent mIAS can become a dose-limiting toxicity. Small ulcerations may cause significant pain and mucosal sensitivity may occur in the absence of clinical changes. Use of clinical assessment tools that are primarily driven by ulceration size may underestimate mIAS, and assessment should include patient-reported outcomes. This article provides an up-to-date review of the clinical presentation, terminology, pathogenesis, assessment and management of mIAS and other mTOR inhibitor-associated oral adverse events. In addition, areas of future research are considered.

Answer: What does mTOR stands for?


Question: Diary of a Wimpy Kid: The Third WheelBy Jeff Kinney A dance at Greg Heffley's middle school is going to be held, but he can't find someone to go with him. Finally he finds a girl from his class to go with him. That is when The Third Wheel story begins. The Third Wheel is full of jokes and interesting drawings. Ivy and Bean Make the RulesBy Annie Barrows Bean's older sister Jessie goes to a summer camp called Girl Power 4-Ever, but Bean can't join her because she is too young. So Bean and her best friend, Ivy, decide to create their own camp. At Camp Flaming Arrow, Ivy and Bean come up with all the activities and, of course, they make the rules. Their happiness and kindness will make you want to keep reading. Stick DogBy Tom Watson Stick Dog is a dog that lives in an empty pipe. He has four dog friends named Poo-Poo, Stripes, Karen and Mutt. When Stick Dog smells some delicious hamburgers, he and his friends decide to steal the food from a human family that is having a picnic in Picas-so Park. Along the way, they face a lot of funny challenges. White Fur FlyingBy Patricia Maclachlan Zoo and Alice's mother might just have the coolest job ever. She rescues Great Pyrenees dogs! But dogs aren't the only things that need to be saved. The family's new neighbour, Philfip, doesn't speak, and no one knows why. White Fur Flying is all about understanding that love can come from both inside and outside. Although it is a little sad, the book is good to read. Kids who love animals and a good story will really like it, too.

Answer:
Who wants to start a camp?