Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.

U.S. scientists said the infection in a 49-year-old Pennsylvania woman “heralds the emergence of truly pan-drug resistant bacteria” because it could not be controlled even by colistin, an antibiotic reserved for “nightmare” bugs. In Japan, British Prime Minister David Cameron said leading countries needed to tackle resistance by reducing the use of antibiotics and rewarding drug companies for developing new medicines. “In too many cases antibiotics have stopped working. That means people are dying of simple infections or conditions like TB (tuberculosis), tetanus, sepsis, infections that should not mean a death sentence,” he told a news conference at a summit in Japan. “If we do nothing about this there will be a cumulative hit to the world economy of $100 trillion and it is potentially the end of modern medicine as we know it.”  A review commissioned by the British government and published last week said a reward of between $1 billion and $1.5 billion should be paid for any successful new antimicrobial medicine brought to market. If the problem is not brought under control, antimicrobial resistance could kill an extra 10 million people a year by 2050, the review warned. The U.S. case is a further wake-up call for the world, although it is not the first time that colistin resistance has appeared. Medics around were alarmed last year by the discovery in China of a new gene that makes bacteria highly resistant to the medicine. Since then, the deadly strain has also been detected in Europe and Canada. The development of colistin resistance is linked to the drug’s widespread use in livestock and the European Medicines Agency on Thursday called for a 65 percent cut in the amount of the medicine used in farming. “The more we look at drug resistance, the more concerned we are,” Thomas Frieden, director of the U.S. Centers for Disease Control and Prevention, told reporters in Washington. “The medicine cabinet is empty for some patients. It is the end of the road for antibiotics unless we act urgently.”  The problem is aggravated by drugmakers’ reluctance to invest in developing new antibiotics, preferring to focus on more profitable disease areas, although recently there has been some increase in investment, prompted by the superbug threat. In January, 83 companies, including Pfizer (PFE.N), Merck & Co (MRK.N), Johnson & Johnson (JNJ.N) and GlaxoSmithKline (GSK.L), signed a declaration urging governments to support work on new antibiotics.
G7 told to act on antibiotics as dreaded superbug hits U.S.

Dr. Nelson Teich, an oncologist and health care consultant, took the job April 17 faced with the task of aligning the ministry’s actions with the president’s view that Brazil’s economy must not be destroyed by restrictions to control spread of the virus. Teich’s predecessor, Luiz Henrique Mandetta, also had rejected the use of chloroquine, which also had been touted by U.S. President Donald Trump as a treatment. Four government ministers who spoke after Teich’s resignation defended the idea of patients being allowed to use the drug if they want to, including Economy Minister Paulo Guedes and the Cabinet chief of staff, Gen. Walter Braga Netto. Officials say almost 15,000 people have died in Brazil from COVID-19, the disease caused by the coronavirus, though some experts say the figure is significantly higher due to insufficient testing. The peak of the crisis has yet to hit Latin America’s largest nation, experts say. Gen. Eduardo Pazuello, who had no health experience until he became the Health Ministry’s No. 2 official in April, will be the interim minister until Bolsonaro chooses a replacement. Brazilian media have said that Teich’s ability to do his job had been weakened by the appointment of dozens of military personnel to jobs in the ministry. “Life is made up of choices and today I decided to leave,” Teich told journalists in capital Brasilia. He did not explain why he left the job and refused to answer questions. Braga Netto, the Cabinet chief, said Teich left the job “for personal reasons.” Bolsonaro did not comment. Teich’s resignation came one day after Bolsonaro told business leaders in a videoconference he would ease rules for using chloroquine to treat people infected with the coronavirus. Teich has frequently called use of the drug “an uncertainty,” and this week warned of its side effects. The Health Ministry previously allowed chloroquine to be used in coronavirus cases only for patients hospitalized in serious condition. At Bolsonaro’s urging, the country’s Army Chemical and Pharmaceutical Laboratory boosted chloroquine production in late March. Researchers last month reported no benefit in a large analysis of the drug or a related substance, hydroxychloroquine, in U.S. hospitals for veterans. Last month, scientists in Brazil stopped part of a study of chloroquine after heart rhythm problems developed in one quarter of people given the higher of two doses being tested. Governors who have recommended quarantine measures and refrained from touting the drug’s unproven potential said Teich’s resignation reflects Bolsonaro’s failure to manage the pandemic. Rio de Janeiro Gov. Wilson Witzel, a former ally of Bolsonaro, said “no one can do serious work with interference in ministries.” “That is why governors and mayors need to lead the pandemic crisis, and not you, Mr. President,” Witzel said on Twitter. The governor of Ceara, one of Brazil’s most hard-hit states, said Teich’s exit “brings enormous insecurity and concern.” “It is unacceptable that in the face of this serious health crisis, the focus of the government is still on political and ideological discussions. That is an affront to the nation,” Camilo Santana said. On April 16, Bolsonaro fired Teich’s predecessor, Mandetta, who had become the embodiment of challenges to the president’s opposition to governors’ quarantine recommendations and restrictions on businesses. Bolsonaro was eager to resume economic activity and warned failure to do so would cause Brazil to descend into “chaos”. Teich took office pledging to balance health care concerns and the president’s economic worries. He did not openly challenge the president’s views, but did defend stay-at-home measures. Miguel Lago, executive director of Brazil’s non-profit Institute for Health Policy Studies, which advises public health officials, said Teich wasn’t able to build his own team, didn’t have Mandetta’s political strength and wasn’t willing to violate the scientific recommendations. “He clearly had limitations,” Lago said. “He would not challenge what has been consensus among the scientific community. He would never accept the chloroquine thing that Bolsonaro wanted him to do, to recommend publicly that chloroquine was a remedy to be used in the public health system.”  Hours after Teich left the job, the Health Ministry began listing figures on chloroquine distribution as part of its main charts about government initiatives against the pandemic, alongside intensive care unit beds, personal protection equipment, tests and flu vaccines. Risk consultancy Eurasia Group analyst Filipe Gruppelli Carvalho said that the Health Ministry’s capacity for ”an effective coordinating role looks to have dropped with Mandetta’s exit,” . “Ultimately, Teich’s dismissal reinforces our view of increasing risks from the government’s poor response to the pandemic, which could contribute to a weaker presidency and decline in support for Bolsonaro in the post-pandemic phase,” he said. The newspaper Folha de S.Paulo published an editorial after Teich’s exit saying Bolsonaro is trying to “put his own survival above state policies and national interest.” “The resignation of another health minister — in less than a month and during the most serious sanitary emergency of contemporary history — exposes the downfall of a president that doesnt’t even pretend to govern the country,” the newspaper said. “As if the economic and sanitary calamities were not enough, he turned himself into a crisis to be faced.” After Teich’s resignation was announced, pot-banging protests were heard in different regions of Sao Paulo and Rio de Janeiro. _____ Associated Press writers David Biller and Diane Jeantet in Rio de Janeiro contributed to this report.
Brazil’s health minister resigns after one month on the job.

Maxwell, 31, started the Australian summer season in strong form when he hit 62 runs off just 28 balls against Sri Lanka on Sunday and executed a run-out from near the Adelaide Oval boundary. Australia won that match by 134 runs and the second on Wednesday by nine wickets, when Maxwell wasn’t required to bat, to clinch the three-match series. Maxwell met with Cricket Australia staff on Wednesday, and is expected to miss the rest of the T20 internationals against Sri Lanka on Friday in Melbourne and against Pakistan in three matches next week. Team psychologist Dr. Michael Lloyd said Thursday that Maxwell “has been experiencing some difficulties with regards to his mental health. As a result, he will spend a short time away from the game ... Glenn was proactive in identifying these issues and engaging with support staff.” Australia coach Justin Langer said he approached Maxwell before Sunday’s match. “There’s been a few times over the last 12 months where I’ve probably suspected that he’s been battling a little bit,” Langer said. “The day before the game in Adelaide he didn’t seem to have his normal zip and enthusiasm, although he still worked hard. “People in public positions have to put on a mask and that’s the mask he puts on. He’s the great entertainer, but underneath the mask I could probably just sense he wasn’t quite right.” D’Arcy Short has been chosen as a replacement player and will join the Australian T20 squad on Friday ahead of the final Sri Lanka match. ___ More AP cricket: www.apnews.com/cricket and https://twitter.com/AP_Sports

Cricketer Maxwell to take break due to mental health issues.