TASK DEFINITION: Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
PROBLEM: Context: Malaria is one of the most devastating infectious diseases in the developing world. Until now, only one candidate malaria vaccine RTS,S/AS01 has shown modest protection in phase 3 trial in African infants. Hence the treatment of malaria still depends on the current chemotherapeutic drugs. Considering the resistance of malaria parasites to almost all used antimalarial drugs, aiming at multi-targets rather than a single target will be a more promising strategy. Previous studies have shown that myricetin and fisetin exhibited in vitro antimalarial activity against Plasmodium falciparum, but very little research focused on the molecular mechanism for their parasiticidal activity. The cysteine protease falcipain-2 and aspartic protease plasmepsin II have long been considered as important antimalarial drug targets, especially combined inhibition of these two proteases. In this study, we determined that myricetin and fisetin are dual inhibitors of falcipain-2 and plasmepsin II, which might account for their antimalarial properties. Overall, the dual inhibition of falcipain-2 and plasmepsin II by myricetin and fisetin has shed light on a possible mechanism for their antimalarial activity and provided a rationale for further development as antimalarial drugs. 
 Question: RTS S AS01 vaccine was developed to prevent which disease?

SOLUTION: malaria

PROBLEM: Context: It seems that the Great Wall is the place to rock . There will be two parties held on the Great Wall this month. Great Wall I The latest Great Wall party is sponsored by the Club and Elektrobeat and held at Jinshanling. Local DJ Mark, as well as guests Slab from Australia, Usami and Bobby from Hong Kong will sing at the party. All drinks are priced at 20 yuan($ 2.4). Tickets: 200yuan($ 24), including bus ride there and back plus entrance fee to the Great Wall. T/D: 8p.m. to 2 a.m., Sept. 20. Pre-sale tickets are to be booked at: Public Space: 6416-0759; Neo Lounge: 6416-1077. Buses: Leave at 5 p.m. on Saturday, Sept. 20 from Neo Lounge, 99 Xinfuncun Zhonglu, Sanlitun, Chaoyang District. For more info: www. elektrobeat. com Great wall II The other party at the end of this month at Jinshanling will be started with live performances by Askar, Brain Failure, Longkuan, Supermarket, Mr. Zhou, Beijing Talking and the Yi band. Dance till dawn to the wonderful sounds of DJs Ben, Mickey Zhang, Will, Cheese, Gao Hu and Huang Weiwei. T/D: 8 p.m. to 2 a.m., Sept. 27. Tickets: 350 yuan ($ 42) or 300 yuan ($ 36) for groups of 10 or more, 500 yuan ($ 60) at the door and VIP tickets 800 yuan ($ 72), transportation included. Buses: Depart from the north gate of Wbrkers' Stadium at noon, 2 p.m., 4 p.m., Sept. 27. For more info: contact Li Zhenhua at lah@msgp. Org or call 133-2119-1731. 
 Question: What day of the week is September 27?

SOLUTION: saturday.

PROBLEM: Context: The Internet will overtake radio in 2008 and become the world's fourth-largest advertising medium, a year earlier than forecast. Global spending on Internet advertising increased from 18.7 billion U.S. dollars in 2005 to 24.9 billion dollars last year, according to Zenith Optimedia, the media-buying agency. The Middle East and Asia are driving a boom in global advertising spending. Zenith predicted _ of 7.7% in spending in Asia in the run-up to the 2008 Olympic Games in Beijing. In the Middle East and Eastern Europe, advertising spending is growing faster than in North America and Western Europe, which are "maturing rapidly" as advertising markets, Zenith said. Advertising spending in the Middle East increased by 22.4% between 2005 and 2006, compared with growth of 5.2% in America and 4 per cent in Western Europe. Zenith attributed the huge percentage share in the Middle East to the growth in local economies and high oil prices. In addition to the Olympics, the U.S. presidential election and the European football championship in Austria and Switzerland next year will be the biggest contributors to overall growth during the next two years. However, Zenith noted, the market should brace itself for a fall in revenues after those big events end. 
 Question: Which has enjoyed the fastest growth of advertising spending in the last year?

SOLUTION:
the middle east.