Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Q: Question: Does nonresponse to pre-operative chemotherapy preclude long-term survival after liver resection in patients with colorectal liver metastases?
Answer: Liver resection offers a long-term survival benefit for patients with CRM, even when tumor growth proceeds during pre-operative chemotherapy.

A: no
****
Q: Question: Is cYP3A5 genotype associated with a higher risk of acute rejection in tacrolimus-treated renal transplant recipients?
Answer: We conclude that patients expressing CYP3A5 need more tacrolimus to reach target concentrations and have a lower tacrolimus exposure shortly after transplantation. This delay in reaching target concentrations, however, did not result in an increased incidence of early BPAR and therefore, genotyping for CYP3A5 is unlikely to improve short-term transplantation outcome.

A: no
****
Q: Question: Is mutation or polymorphism of the CD20 gene associated with the response to R-CHOP in diffuse large B cell lymphoma patients?
Answer: Our results do not support association of CD20 mutations in specimens of the initial tumor or structural polymorphisms of the CD20 gene with patients who exhibited poor outcomes to R-CHOP.

A:
no
****