Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[Q]: ZFHX1B encodes Smad-interacting protein 1, a transcriptional corepressor involved in the transforming growth factors beta (TGFbeta) signaling pathway. ZFHX1B mutations cause a complex developmental phenotype characterized by severe mental retardation (MR) and multiple congenital defects. We compared the distribution of ZFHX1B transcripts during mouse and human embryogenesis as well as in adult mice and humans. This showed that this gene is strongly transcribed at an early stage in the developing peripheral and central nervous systems of both mice and humans, in all neuronal regions of the brains of 25-week human fetuses and adult mice, and at varying levels in numerous nonneural tissues. Northern blot analysis suggested that ZFHX1B undergoes tissue-specific alternative splicing in both species. These results strongly suggest that ZFHX1B determines the transcriptional levels of target genes in various tissues through the combinatorial interactions of its isoforms with different Smad proteins. Thus, as well as causing neural defects, ZFHX1B mutations may also cause other malformations.
[A]: Which gene is responsible for the development of the Mowat-Wilson syndrome?


[Q]: Brigadier Sir Iltyd Nicholl Clayton CBE (1886 -- 30 June 1955) was a British Army officer notable for his attachment to the Middle East Office in Cairo during and after World War II and his involvement in the formation of Arab League and formulation of post-war British policy in the Middle East.
[A]: Who did Iltyd Nicholl Clayton serve for?


[Q]: Seiffert Oval is a rugby league ground in Queanbeyan, New South Wales that served as the base of the Canberra Raiders for the first seven years of its existence (1982-1989).
[A]:
What team uses Seiffert Oval?