Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Q: Chediak-Higashi syndrome (CHS) is a rare multiorgan disease entity with autosomal recessive inheritance characterized by oculocutaneous albinism, bleeding tendency, recurrent bacterial infections and various neurological symptoms. Intracellular vesicle formation is deficient, resulting in giant granules in many cells, e.g. giant melanosomes in the melanocytes. Diagnosis has been based on morphological examination of peripheral blood and bone marrow, with giant granules seen in cells of the myeloid lineage and in lymphocytes. The ultimate diagnostic test is to look for a mutated LYST gene. Most patients develop an accelerated phase of the disease with deposition of lymphohistiocytes in the liver, spleen, lymph nodes and bone marrow, resulting in hepatosplenomegaly, bone marrow infiltration and haemophagocytosis. Peripheral blood neutropenia becomes more profound as anaemia and thrombocytopenia develop. Most patients succumb before the age of 10 years. Four patients with CHS are described, one of whom is a long-term survivor after successful allogeneic bone marrow transplantation, two succumbed during the accelerated phase and one is living with a chronic form of the disease. Allogeneic bone marrow transplantation from an HLA-matched sibling is the therapy of choice and should be performed early. If there is no matched family donor, an unrelated donor or a placental blood graft is a good alternative. The clinical picture of CHS is heterogeneous and therapeutic decisions need to be made on an individual basis.

A: Which mutated gene causes the Chédiak–Higashi Syndrome?
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Q: NGC 4030 is a grand design spiral galaxy located about 64 million light years away in the constellation Virgo.

A: The star NGC 4030 is part of the constellation known as what?
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Q: A huge cloud of dust rose and an overpass disappeared. This was the scene in Zhuzhou,Hunan Province on May 17.Nine people were killed and 16 injured. Things were similar last year in the Sichuan earthquake. Thousands of people were buried in the ruins and lost their lives. What if we could have warned them? People are always _ to find a way of preventing buildings' collapse. Better materials and technology help,but they are not a solution. Just like humans,a building has its own life cycle from "birth" to "death".If we know when a building is going to collapse,we can repair it in advance or get out of it before it falls. Now,scientists at the University of Illinois have developed a material that turns red before it breaks. The invention could be used in things like climbing ropes or bridge supports. The research was led by Nancy Sottos,a professor at the university's Beckman Institute,and Douglas Davis,a graduate research assistant. The secret behind the colorchanging material is a type of molecule .A molecule is a group of atoms held together by chemical bonds. Imagine you and your friends standing in a circle,holding hands. Each person stands for one atom,your hands represent the bonds,and the entire circle represents a molecule. If one person lets go of his or her hands,the molecule changes color. The research team put the molecule into a soft material. When the researchers stretched the material,it turned bright red for a few seconds before it broke into two pieces. When they repeatedly stretched and relaxed the material,without breaking it,it only turned a little red. The major problem is that light can get rid of the red color. When the team shone bright light on the molecule,the broken bond was fixed,and the color disappeared. If the bright light keeps the red color from appearing,the material's warning system will be useless. Scientists still have a lot of work to do before the colorchanging molecules can be used outside the lab.

A:
What does the passage mainly introduce?
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