Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: Coagulation parameters of 3 different time-points were assessed and compared: before administration of any blood product (time-point 1), before administration of the first dose of rFVIIa (time-point 2), and 4 hours after the administration of the last dose of rFVIIa (time-point 3).
Example Output: non-adverse drug event

Example Input: Phenobarbital hepatotoxicity in an 8-month-old infant.
Example Output: adverse drug event

Example Input: No organisms could be grown by culture of corneal scrapings for bacteria and fungi, and the condition failed to respond to topical therapy.
Example Output:
non-adverse drug event