In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

Example Input: A randomized, double-blind, placebo-controlled clinical trial was conducted to evaluate the ability of Echinacea purpurea to prevent infection with rhinovirus type 39 (RV-39). Forty-eight previously healthy adults received echinacea or placebo, 2.5 mL 3 times per day, for 7 days before and 7 days after intranasal inoculation with RV-39. Symptoms were assessed to evaluate clinical illness. Viral culture and serologic studies were performed to evaluate the presence of rhinovirus infection. A total of 92% of echinacea recipients and 95% of placebo recipients were infected. Colds developed in 58% of echinacea recipients and 82% of placebo recipients ( , by Fisher's exact test). Administration of echinacea before and after exposure to rhinovirus did not P p .114 decrease the rate of infection; however, because of the small sample size, statistical hypothesis testing had relatively poor power to detect statistically significant differences in the frequency and severity of illness. Colds are the most common acute infectious illnesses in humans. Prevention of the common cold with immunization is not practical because of the antigenic diversity of the many viruses causing colds. For example, rhinoviruses, which account for ∼40% of adult colds, have 1100 antigenic serotypes. Viruses of different and distinct families, such as coronavirus, parainfluenza virus, respiratory syncytial virus, influenza virus, adenovirus, and metapneumovirus, also cause colds. Products derived from Echinacea purpurea, the purple coneflower, are among the most popular herbal remedies in the United States. It is estimated that Americans spend more than $300 million/year on these products [1], which are commonly self-administered for the prevention and treatment of the common cold. The 3
Example Output: Echinacea purpurea for Prevention of Experimental Rhinovirus Colds

Example Input: This article employs a state-of-the-art panel threshold model by allowing for regime intercepts, in order to shed new light on the asymmetric/ nonlinear effects of local and global sentiments on expected industry stock returns among 11 Asian countries during the period from 1996 to 2010. Empirical evidence demonstrates that once the regime intercept is included, the asymmetric effects of global sentiment on oil & gas, financials, and health care industry returns become less under optimism, as compared with under pessimism. More critically, the positive (negative) impact of global sentiment above (under) the threshold turns significant, indicating that global optimism leads industry returns to be overvalued, while pessimism leads them to be undervalued. For local market sentiment, our results support that higher local sentiment enhances the returns of basic materials, telecommunications, and utilities industries. The empirical results confirm that the nexus of industry returns and investor sentiments is subject to change between different sentimental intervals.
Example Output: Asymmetric effects of investor sentiment on industry stock returns: Panel data evidence

Example Input: The bacterial bipartite transferrin receptor is an iron acquisition system that is required for 12 survival by several key human and animal pathogens. It consists of the TonB-dependent 13 transporter Transferrin binding protein A (TbpA) and the surface lipoprotein Transferrin binding 14 protein B (TbpB). Curiously, the Tbps are only found in host specific pathogens, and are 15 themselves host specific, meaning that they will bind to the transferrin of their host species, but 16 not to those of other animal species. While this phenomenon has long been established, neither 17 the steps in the evolutionary process that led to this exquisite adaptation for the host, nor the 18 steps that could alter it, are known. We sought to gain insight into these processes by studying 19 Tbp specificity in Histophilus somni, a major pathogen of cattle. A past study showed that whole 20 cells of H. somni specifically bind bovine transferrin, but not transferrin from sheep and goats, 21 two bovids whose transferrins share 93% amino acid sequence identity with bovine transferrin. 22 To our surprise, we found that H. somni can use sheep and goat transferrins as iron sources for 23 growth, and that HsTbpB, but not HsTbpA, has detectable affinity for sheep and goat 24 transferrins. Furthermore, a third transferrin binding protein, HsTbpA2, also showed affinity for 25 sheep and goat transferrins. Our results show that H. somni TbpB and TbpA2 act to broaden the 26 host transferrin recognition range of H. somni. 27
Example Output:
Transferrin binding protein B and Transferrin binding protein A 2 expand the transferrin 1 recognition range of Histophilus somni 2 3 Running title: TbpB and TbpA2 broaden specificity of