Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: CASE REPORT: A 64-year-old female patient with metastasized esophageal carcinoma received simultaneous chemoradiotherapy of the upper mediastinum with 50.4 Gy and cisplatin/5-fluorouracil.

Output: non-adverse drug event


Input: Consider Input: PURPOSE: Symptomatic visual field constriction thought to be associated with vigabatrin has been reported.

Output: adverse drug event


Input: Consider Input: A 55- year-old man had been followed for chronic hepatitis B infection for 10 years at another institution.


Output: non-adverse drug event