Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Q: Question: Does tobacco smoking differently influence cell types of the innate and adaptive immune system-indications from CpG site methylation?
Answer: Studying cell type-specific methylation changes provides helpful information regarding the biological relevance of epigenetic modifications. Here, we could show that smoking differently affects both cells of the innate and adaptive immune systems.

A: yes
****
Q: Question: Does pEEP ventilation cause humorally mediated cardiac output depression in pigs?
Answer: As humorally mediated negative inotropism during PEEP ventilation has earlier been demonstrated in dogs, the results suggest that this mechanism might be species-dependent.

A: no
****
Q: Question: Does fatigue-induced ACL injury risk stem from a degradation in central control?
Answer: Unilateral fatigue induces a fatigue crossover to the contralateral limb during single-leg landings. Central fatigue thus seems to be a critical component of fatigue-induced sports landing strategies. Hence, targeted training of central control processes may be necessary to counter successfully the debilitative impact of fatigue on ACL injury risk.

A:
yes
****