Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Q: There had been one episode of chest discomfort in her past history.

A: non-adverse drug event
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Q: RESULTS: Withdrawal of oral colchicine therapy was followed by rapid corneal wound healing in both patients.

A: non-adverse drug event
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Q: The nocturia was defined as having more than two episodes of urination during sleep per night on average.

A:
non-adverse drug event
****