TASK DEFINITION: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
PROBLEM: CONCLUSIONS: We report this case of the concomitant appearance of multiple skin cancers and nail changes associated with hydroxyurea use.

SOLUTION: adverse drug event

PROBLEM: Because of its favorable tolerability profile it appears to be a preferred alternative, especially in NSAID-sensitive patients.

SOLUTION: non-adverse drug event

PROBLEM: Ticlopidine-induced aplastic anemia: two new case reports, review, and meta-analysis of 55 additional cases.

SOLUTION:
adverse drug event