In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Q: Question: Point out the correct answer in relation to the monitoring of plasma drug concentrations: 
 Options:  <1> Allergy reactions are related to the dose administered. <2> The extraction of the blood sample must be done once the balance of drug distribution in the organism has been reached. <3> The information provided by the analytical determination of plasma concentration is sufficient to perform the dosage individualization. <4> Only the immunoassay methods are valid for carrying out the analytical determination of the blood samples. <5> It must be done for all drugs that are administered intravenously.

A: 2
****
Q: Question: Nitric oxide: 
 Options:  <1> It is synthesized from methionine. <2> Activates cAMP-dependent protein kinase (PKA). <3> It binds to receptors coupled to G proteins (GPCR). <4> Induces relaxation of the vascular endothelium. <5> It binds to receptors with protein tyrosine kinase (PTK) activity.

A: 4
****
Q: Question: The evaluation of the electrodermal activity allows a measurement of: 
 Options:  <1> The general activation of the Autonomic Nervous System. <2> The parasympathetic activation. <3> The visceral activity. <4> The cortical attitude. <5> The Delta rhythm.

A:
1
****