Given a text passage, come up with an appropriate title for it. The title should accurately represent what the main focus of the passage is. The title of a passage may be present in the first few sentences of the passage and/or be referred to multiple times in the passage. The title should be 1-5 words long.

Q: The League of Nations ( abbreviated as LN in English , La Société des Nations ( la sɔsjete de nɑsjɔ̃ ) abbreviated as SDN or SdN in French ) was an intergovernmental organisation founded on 10 January 1920 as a result of the Paris Peace Conference that ended the First World War . It was the first international organisation whose principal mission was to maintain world peace . Its primary goals , as stated in its Covenant , included preventing wars through collective security and disarmament and settling international disputes through negotiation and arbitration . Other issues in this and related treaties included labour conditions , just treatment of native inhabitants , human and drug trafficking , the arms trade , global health , prisoners of war , and protection of minorities in Europe . At its greatest extent from 28 September 1934 to 23 February 1935 , it had 58 members .

A: League of Nations
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Q: Mescalero or Mescalero Apache is an Apache tribe of Southern Athabaskan Native Americans . The tribe is federally recognized as the Mescalero Apache Tribe of the Mescalero Apache Reservation , located in south central New Mexico .

A: Mescalero
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Q: Transition state analogs ( transition state analogues ) , are chemical compounds with a chemical structure that resembles the transition state of a substrate molecule in an enzyme - catalyzed chemical reaction . Enzymes interact with a substrate by means of strain or distortions , moving the substrate towards the transition state . Transition state analogs can be used as inhibitors in enzyme - catalyzed reactions by blocking the active site of the enzyme . Theory suggests that enzyme inhibitors which resembled the transition state structure would bind more tightly to the enzyme than the actual substrate . Examples of drugs that are transition state analog inhibitors include flu medications such as the neuraminidase inhibitor oseltamivir and the HIV protease inhibitors saquinavir in the treatment of AIDS .

A:
Transition state analog
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