Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
The case histories are presented of two patients who developed lung disease associated with the use of nitrofurantoin with histological features of bronchiolitis obliterans organising pneumonia (BOOP), a rare but recognised form of drug induced injury.

Ex Output:
adverse drug event


Ex Input:
The first was a 56-year-old male treated with multiple chemotherapeutics for multiple myeloma.

Ex Output:
non-adverse drug event


Ex Input:
The aim of this study was to describe the occurrence of acute coronary syndromes in 3 cases of rituximab infusions.

Ex Output:

adverse drug event