Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
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Question: Ulcerative proctitis in juvenile systemic lupus erythematosus after ibuprofen treatment.

Answer: adverse drug event


Question: In patients who show abnormal liver function tests, the immediate discontinuation of gliclazide is recommended.

Answer: non-adverse drug event


Question: Conspicuous endoscopic appearance of ventriculitis caused by coagulase-negative staphylococci.

Answer:
non-adverse drug event