In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: Pulmonary hypertension occurs as a consequence of: 
 Options:  <1> Bronchoconstriction and inflammation of the upper respiratory tract. <2> Bronchoconstriction and inflammation of the lower respiratory tract. <3> Bronchiectasis and pulmonary collapse. <4> Vasoconstriction of the arterioles of the systemic circulation. <5> Vasoconstriction of the arterioles of the pulmonary circulation.
5

Question: With what scope is the Theory of the Melzack Gate and Wall related ?: 
 Options:  <1> Cancer. <2> HIV infection <3> Renal problems. <4> Pain. <5> Cardiovascular disorders
4

Question: The clinical specificity of an analytical parameter (test), with respect to a certain pathology, is defined as: 
 Options:  <1> The mean concentrations of this test in healthy patients. <2> A pathological concentration of the test in the presence of the disease. <3> A pathological concentration of the test in the absence of the disease. <4> A normal concentration of the test in the absence of the disease. <5> A normal concentration of the test in the presence of the disease.

4