In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Ex Input:
Question: A key reaction in the regulation of gene expression is acetylation / desatethylation in the histones of some of its residues: 
 Options:  <1> Serina <2> Threonine <3> Lysine <4> Tryptophan <5> To the girl.

Ex Output:
3


Ex Input:
Question: With regard to pyrogens and biotechnological medicines, it is possible to say: 
 Options:  <1> They have no tendency to aggregate or form large units with high molecular weight. <2> Ion exchange chromatography procedures (using their positive charge) can reduce endotoxin levels. <3> Ion exchange chromatography procedures (using their negative charge) can reduce endotoxin levels. <4> Ion exchange chromatography procedures (regardless of their charge) can reduce endotoxin levels. <5> They are unstable under standard autoclaving conditions.

Ex Output:
3


Ex Input:
Question: A 20-year-old boy goes to the emergency room for fever of 39ºC, chills, papules and hemorrhagic pustules on the distal extensor surfaces of the extremities and arthritis of the knee. What is your diagnosis of initial suspicion? 
 Options:  <1> Rheumatoid arthritis. <2> Reiter syndrome. <3> Urica Drop <4> Gonococcal arthritis. <5> Vasculitis of Cogan.

Ex Output:

4