instruction:
Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
question:
Context: Min and Bill is a 1930 American Pre-Code comedy-drama film starring Marie Dressler and Wallace Beery and based on Lorna Moon's novel Dark Star, adapted by Frances Marion and Marion Jackson. 
 Question: The Min and Bill is based upon what?
answer:
lorna moon


question:
Context: The circumsporozoite protein (CS protein) on the malaria parasites in mosquitoes plays an important role in sporogony in mosquitoes. The RTS,S/AS01 malaria vaccine candidate, which has shown significant efficacy against clinical malaria in a large Phase 3 trial, targets the Plasmodium falciparum CS protein, but the ability of serum from vaccinated individuals to inhibit sporogony in mosquitoes has not been evaluated. Previously a double-blind, randomized trial of RTS,S/AS01 vaccine, as compared with rabies vaccine, in five- to 17-month old children in Tanzania was conducted. In this study, polyclonal human antibodies were purified from the pools of sera taken one month after the third vaccination. IgGs were purified from four pools of sera from 25 RTS,S/AS01 vaccinated children each, and two pools of sera from 25 children vaccinated with rabies vaccine each. The ability of antibodies to inhibit P. falciparum oocyst formation and/or sporogony in the mosquito host was evaluated by a standard membrane-feeding assay. The test antibodies were fed on day 0 (at the same time as the gametocyte feed), or on days 3 or 6 (serial-feed experiments). The oocyst and sporozoite counts were performed on days 8 and 16, respectively. In addition, two human anti-CS monoclonal antibodies (mAb) and a control mAb were also evaluated. Polyclonal anti-CS IgG preparations from RTS,S-vaccinated children tested at concentrations of 149-210 ELISA units (EU)/ml did not show significant inhibition in oocyst and sporozoite formation when the antibodies were fed with gametocytes at the same time, or later (serial-feed experiments). Similarly, anti-CS mAbs tested at 6,421 or 7,122 EU/ml did not show reduction in oocyst and sporozoite formation. This study does not support the concept that anti-CS antibodies induced by the RTS,S/AS01 vaccines in humans noticeably reduce malaria transmission by blocking P. falciparum sporozoite development or salivary gland invasion in mosquitoes when taken up during feeding. 
 Question: RTS S AS01 vaccine was developed to prevent which disease?
answer:
malaria


question:
Context: When you look at the sky on a clear night, you can see dozens, perhaps even hundreds, of tiny points of light. Almost every one of these points of light is a star, a giant ball of glowing gas at a very, very high temperature. Stars differ in size, temperature, and age, but they all appear to be made up of the same elements and to behave according to the same principles. People of many different cultures, including the Greeks, identified patterns of stars in the sky. We call these patterns constellations. Figure 1.1 shows one of the most easily recognized constellations. Why do the patterns in constellations and in groups or clusters of stars, called asterisms, stay the same night after night? Although the stars move across the sky, they stay in the same patterns. This is because the apparent nightly motion of the stars is actually caused by the rotation of Earth on its axis. The patterns also shift in the sky with the seasons as Earth revolves around the Sun. As a result, people in a particular location can see different constellations in the winter than in the summer. For example, in the Northern Hemisphere Orion is a prominent constellation in the winter sky, but not in the summer sky. This is the annual traverse of the constellations. Although the stars in a constellation appear close together as we see them in our night sky, they are not at all close together out in space. In the constellation Orion, the stars visible to the naked eye are at distances ranging from just 26 light-years (which is relatively close to Earth) to several thousand light-years away. Click image to the left or use the URL below. URL: There is no reason to think that the alignment of the stars has anything to do with events that happen on Earth. The constellations were defined by people who noticed that patterns could be made from stars, but the patterns do not reflect any characteristics of the stars themselves. When scientific tests are done to provide evidence in support of astrological ideas, the tests fail. When a scientific idea fails, it is abandoned or modified. Astrologers do not change or abandon their ideas. Click image to the left or use the URL below. URL: 
 Question: in winter and in summer, people in a given location see
answer:

different constellations.