instruction:
Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
question:
Loma just had to get in touch with someone:"I had to tell my best friend something important. I tried calling her but I couldn't get through. So I sent her an e-mail and then I spoke to her on MSN. Without technology I would not have been able to tell her. " Staying connected with friends and family is important for us. That's why we asked our readers to tell us how cell-phones, e-mail, blogs, text messaging, and personal pages help them keep in touch. More than 1,500 responded. Most of them told us they couldn't live without technology:80%of teens said they need technology to stay in touch. Almost 30%said they'd be completely out of their friends without their cell-phones and other methods of communication. What do they do when they've got news they need to share now? Most teens say they try to reach their friends by phone. But if they don't reach them, they use QQ, e-mails, and text messaging to _ Lots of people use one way of communication--like text messaging--to get a friend's attention and then use another where they can talk more. "My friends and I always tell each other everything that happens. So I send them text messages to tell them to come online so we can talk about it," said Sabeiha. "When planning to get together with friends", Julian said, "the easiest and fastest way I know is to send a text message to my contact group." Jocelyn said. "If I want to go to see a movie with a few friends, I usually send text message to them. By telephone, you have to call every single friend one by one. But text messaging allows you to send the same message to as many as you'd like, which saves a lot of time.
answer:
What do most young people use first when they have news to tell their friends?


question:
The antiparallel side-to-side association of spectrin alpha and beta monomers is a two-step process which occurs in seconds even at 0 degrees C and at low concentrations. Assembly involves initial contact of complementary nucleation sites on each subunit, which are located near the actin binding end of the long, flexible heterodimer rod. The minimum nucleation sites are comprised of approximately four contiguous 106-residue homologous segments or repeats. Three repeats in the nucleation site contain an 8-residue insertion and have the highest homology to the four spectrin-like repeats in alpha-actinin. The adjacent actin binding domain on the beta subunit and the adjacent EF hand motifs on the alpha subunit are not required for heterodimer assembly. The nucleation sites probably have a specific lock and key structure which defines the unique side-to-side pairing of the many homologous segments in both subunits. Assembly of spectrin heterodimers is probably most analogous to a zipper. After initial nucleation site binding, the remainder of the subunits quickly associate along their full lengths to reconstitute a normal dimer by supercoiling around each other to form a rope-like, flexible rod. Assembly is terminated if either polypeptide is interrupted by a protease cleavage. Heterozygotic mutations involving either nucleation site are predicted to affect allele incorporation into the mature membrane skeleton.
answer:
Alpha-spectrin and beta-spectrin subunits form parallel or antiparallel heterodimers?


question:
In order to determine the prevalence of latent infection due to Mycobacterium tuberculosis in drug users and to provide centres for drug users with a practical tool for tuberculosis screening, 237 drug users were subjected to the Monotest and, for reference purposes, to the Mantoux test. The overall prevalence of subjects with a tuberculin skin reaction size > or = 5 mm in the Mantoux test was 25.7%; utilizing a cut-off of > or = 10 mm, the prevalence was 11.4%. Irrespective of cut-off, the Monotest showed a sensitivity of > 90% and a specificity of > 80%. At a prevalence of 25.7%, and with cut-offs of > or = 5 or > or = 10 mm, the positive predictive value was 83% or 62.2%, respectively. Irrespective of cut-off, the negative predictive value was > 97%. In conclusion, the Monotest proved satisfactory as a tool for epidemiological screening in a population with a high prevalence for latent tuberculosis, namely drug users.
answer:

The Mantoux test detects what latent infection/disease?