Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Context: Peter van Straaten (born 25 March 1935 in Arnhem) is a Dutch cartoonist and comics artist. 
 Question: What was the nationality of Peter van Straaten?
dutch

Context: Secukinumab, a fully human anti-interleukin-17A monoclonal antibody, demonstrated efficacy and safety in moderate-to-severe plaque psoriasis when administered via subcutaneous injection. Self-administration by pre-filled syringe (PFS) can offer patients clinical benefits of a drug, with increased convenience. To assess efficacy, safety and usability of secukinumab administration via PFS in subjects with moderate-to-severe plaque psoriasis. Subjects in this phase 3 trial were randomized 1:1:1 to secukinumab 300 or 150mg or matching placebo. Results to week 12 are presented here. Each treatment was delivered using a PFS once weekly to week 4, and again at week 8. Co-primary endpoints were secukinumab superiority over placebo for week 12 PASI 75 (75% reduction in Psoriasis Area and Severity Index) and IGA mod 2011 (2011 modified Investigator's Global Assessment) 0/1 response rates. Secondary endpoints included PFS usability, determined by observer rating of successful, hazard-free self-injection and subject rating of acceptability by the Self-Injection Assessment Questionnaire (SIAQ). Co-primary endpoints were met, with demonstration of superiority for each secukinumab dose vs. placebo at week 12 (PASI 75: 759%, 695% and 0% for secukinumab 300mg, 150mg and placebo; IGA mod 2011 0/1: 690%, 525% and 0%, respectively; P<00001 for all comparisons vs. placebo). PFS usability was high: 100% of subjects successfully self-administered treatment at week 1, and subjects reported high SIAQ-assessed acceptability of the PFS throughout the trial. No new/unexpected safety signals were observed. Secukinumab administration by PFS was effective, with an acceptable safety profile and high usability. The PFS provides a reliable, convenient form of secukinumab administration in subjects with moderate-to-severe plaque psoriasis. 
 Question: Which molecule is targeted by a monoclonal antibody Secukinumab?
interleukin-17a

Context: A cynical and gothic look at Hollywood during the late 1930s, The Day of the Locust tells the tales of residents of the dilapidated San Bernardino Arms: Faye Greener, a trashy aspiring actress with limited talent, and her father Harry, a washed-up vaudevillian reduced to working as a door-to-door salesman; sexually repressed accountant Homer Simpson, who desperately loves Faye, and East Coast WASP Tod Hackett, an aspiring artist employed by the production department of a major studio, who also fancies Faye. There are unusual and bizarrely disturbing images: a middle-aged man sits in an untended garden staring at a large lizard that stares back; a young woman is transported into the film she's watching and finds herself portraying a harem girl in old Baghdad; a dwarf tenderly caresses a rooster, bleeding and dazed from a cock-fight, and then tosses it back into the ring to its death; an androgynous child beckons to a man through a window and performs a grotesque imitation of Mae West. These brief vignettes do little to advance the basic plot, but they serve to shape the audience's understanding of the era depicted as one of Hollywood sleaziness and wholesale alienation. Spectacle fills the screena set of the Waterloo battlefield collapses on the extras during the making of the film within the film. In the film's climax, an enraged Homer brutally tramples a child near Grauman's Chinese Theater as crowds gather for the premiere of a new film. Seeing this, the enraged crowd swarms over and kills Homer. Almost immediately, the entire crowd is driven to riot, turning on itself, smashing store windows, overturning cars, beating each other to death and turning the already packed street into a war zone. Severely injured, a delirious Tod imagines some of the mob taking on the appearance of the characters in his own grotesque painting The Burning of Los Angeles. 
 Question: What does Hackett visualize as his major work?

the burning of los angeles