Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Input: Consider Input: Question: Does creatine supplementation affect kidney function in an animal model with pre-existing renal failure?
Answer: Creatine supplementation at a dosage of 2% w/w for 4 weeks does not impair kidney function in animals with pre-existing renal failure or in control animals.

Output: no


Input: Consider Input: Question: Is recent unstable angina and off-pump coronary artery bypass grafting related to postoperative atrial fibrillation?
Answer: Post-CABG AF is associated with more complicated postoperative outcome. Recent unstable angina and off-pump procedure is not related to the occurrence of post-CABG AF.

Output: no


Input: Consider Input: Question: Is expression of growth arrest and DNA damage inducible 45a in human oral squamous cell carcinoma associated with tumor progression and clinical outcome?
Answer: The results showed that Gadd45a was redistributed to cytoplasm in poorly differentiated carcinoma from its nucleus location in normal tissue (P < 0.05). The expression of Gadd45a was significantly associated with lymph node metastasis, tumor stage and tumor histological grade (P < 0.05). Knockdown of Gadd45a gene abolished the G2/M arrest and increased migrating ability of Tca8113 cell (P < 0.05). The results indicate that Gadd45a play an important role in OSCC metastasis by affecting the bioactivity of the tumor cells, and its distribution may serve for the prediction of clinical outcome of OSCC.


Output: yes