Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
All patients except two had new recurrences within the observation time.

Ex Output:
non-adverse drug event


Ex Input:
Oncologists supervising future clinical trials for lung cancer should be alert to the fact that sorafenib can potentially induce serious interstitial lung disease, although this might depend on racial differences.

Ex Output:
adverse drug event


Ex Input:
A challenge with clozapine was feasible and showed no clinical symptoms of eosinophilia.

Ex Output:

non-adverse drug event