instruction:
Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
question:
Context: Imatinib mesylate is a new drug that can inhibit the tyrosine kinase activity of Bcr-Abl, the receptors for platelet-derived growth factor receptor(PDGF) and stem cell factor, or c-kit. Chronic myeloid leukemia (CML) is distinguished by the presence of a reciprocal translocation between chromosomes 9 and 22 that results in a shortened chromosome 22, termed the Philadelphia(Ph) chromosome. As a result of the translocation, a fusion gene called the Bcr-Abl gene is created from two normal cellular genes, encoding a chimeric Bcr-Abl protein with a deregulated tyrosine kinase activity. The expression of Bcr-Abl tyrosine kinase has been shown to be necessary and sufficient for the transformed phenotype of CML cells. Imatinib can block the kinase activity of Bcr-Abl, thus inhibiting the proliferation of Ph-positive progenitors, and has shown activity against all phases of CML, though responses are most substantial and durable in patients in the chronic phase. An international phase III study which compared the efficacy of imatinib with that of interferon alpha combined with low-dose cytarabine in newly diagnosed chronic-phase CML showed the rate of major cytogenetic response at 24 months was 90%, including 82% of complete cytogenetic response. These results indicated that imatinib was superior to interferon-containing treatment as a first-line therapy. More than 10,000 patients worldwide, including those in Japan, have been treated with imatinib in clinical trials, and a lot of information has been accumulated on the use of this drug. The aim of this article is to review the use of this drug and the practical management of patients with chronic myeloid leukemia. 
 Question: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?
answer:
bcr-abl


question:
Context: During the war, the Russian army organized the Crimean campaigns of 1687 and 1689 both which ended in Russian defeats. Despite these setbacks, Russia launched the Azov campaigns in 1695 and 1696, and after raising the siege in 1695 successfully occupied Azov in 1696. 
 Question: who lost the Crimean Campaigns?
answer:
russia


question:
Context: The French Revolution broke out in 1789. At the time France was in a crisis. The government was badly run and people's lives were miserable. King Louis XIV tried to control the national parliament and raise more taxes. But his effort failed. He ordered his troops to Versailles. The people thought that Louis intended to put down the Revolution by force. On July 14, 1789, they stormed and took the Bastille, where political prisoners were kept. Ever since that day, July 14 has been the French National Day. Louis tried to flee the country in 1792, to get support from Austria and Prussia. However, he was caught and put in prison. In September 1792, the monarchy was abolished _ . In the same year, Louis was executed. A few months later his wife, Marie also had her head cut off. The Revolution of France had frightened the other kings of Europe. Armies from Austria and Prussia began to march against France. The French raised republican armies to defend the nation. The Revolution went through a period of terror. Thousands of people lost their lives. In the end, power passed to Napoleon Bonaparte. 
 Question: What's this passage about?
answer:

the french revolution.