Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[EX Q]: Ponds are small bodies of fresh water that usually have no outlet; ponds are often are fed by underground springs. Like lakes, ponds are bordered by hills or low rises so the water is blocked from flowing directly downhill. Lakes are larger bodies of water. Lakes are usually fresh water, although the Great Salt Lake in Utah is just one exception. Water usually drains out of a lake through a river or a stream and all lakes lose water to evaporation. Lakes form in a variety of different ways: in depressions carved by glaciers, in calderas (Figure 1.1), and along tectonic faults, to name a few. Subglacial lakes are even found below a frozen ice cap. As a result of geologic history and the arrangement of land masses, most lakes are in the Northern Hemisphere. In fact, more than 60% of all the worlds lakes are in Canada most of these lakes were formed by the glaciers that covered most of Canada in the last Ice Age (Figure 1.2). Lakes are not permanent features of a landscape. Some come and go with the seasons, as water levels rise and fall. Over a longer time, lakes disappear when they fill with sediments, if the springs or streams that fill them diminish, (a) Crater Lake in Oregon is in a volcanic caldera. Lakes can also form in volcanic craters and impact craters. (b) The Great Lakes fill depressions eroded as glaciers scraped rock out from the landscape. (c) Lake Baikal, ice coated in winter in this image, formed as water filled up a tectonic faults. Lakes near Yellowknife were carved by glaciers during the last Ice Age. or if their outlets grow because of erosion. When the climate of an area changes, lakes can either expand or shrink (Figure 1.3). Lakes may disappear if precipitation significantly diminishes. Large lakes have tidal systems and currents, and can even affect weather patterns. The Great Lakes in the United States contain 22% of the worlds fresh surface water (Figure 1.1). The largest them, Lake Superior, has a tide that rises and falls several centimeters each day. The Great Lakes are large enough to alter the weather system in Northeastern United States by the lake effect, which is an increase in snow downwind of the relatively warm lakes. The Great Lakes are home to countless species of fish and wildlife. Many lakes are not natural, but are human-made. People dam a stream in a suitable spot and then let the water back up behind it, creating a lake. These lakes are called "reservoirs." Click image to the left or use the URL below. URL:
[EX A]: which of these is not full of fresh water?

[EX Q]: To study the mechanism of centrosome duplication in cycling cells, we established a novel system of multiple centrosome formation in two types of cells: CHO cells treated with RO3306, a Cyclin-dependent kinase 1 (Cdk1) inhibitor and DT40 cells, in which Cdks were knocked out by chemical genetics. Cdk1-inactivated cells initiated DNA replication and centrosome duplication at the onset of S phase. They became arrested at the end of G2, but the centrosome cycle continued to produce supernumerary centrioles/centrosomes without DNA endoreplication in those cells. Centrosomes were amplified in a highly synchronous and reproducible manner: all of them were located next to the nucleus and spread widely apart from each other with several m in distance. Double knockout of Cdk1 and Cdk2 caused cell cycle arrest at G1/S and centrosomes were no longer duplicated. However, cells continued to grow and increased their volume over 10-fold during 48 hr of culture. Centrosome components, including -tubulin and Cep135, were synthesized and accumulated during the arrest, allowing rapid centrosome multiplication upon recovery from the cell cycle arrest or expression of exogenous Plk4 in G1/S cells. Thus centrosome amplification results from the discoordination of the centrosome cycle from the progression of other cell cycle events, which is controlled by different levels of Cdk activities.
[EX A]: Where in the cell do we find the protein Cep135?

[EX Q]: A common misconception is that the Sun is closer to Earth in the summer and farther away from it during the winter. Instead, the seasons are caused by the 23.5o tilt of Earths axis of rotation relative to its plane of orbit around the Sun (Figure 1.1). Solstice refers to the position of the Sun when it is closest to one of the poles. At summer solstice, June 21 or 22, Earths axis points toward the Sun and so the Sun is directly overhead at its furthest north point of the year, the Tropic of Cancer (23.5o N). During the summer, areas north of the Equator experience longer days and shorter nights. In the Southern Hemi- sphere, the Sun is as far away as it will be and so it is their winter. Locations will have longer nights and shorter days. The opposite occurs on winter solstice, which begins on December 21. More about seasons can be found in the Atmospheric Processes chapter. Different parts of the Earth receive different amounts of solar radiation. Which part of the planet receives the most solar radiation? The Suns rays strike the surface most directly at the Equator. Different areas also receive different amounts of sunlight in different seasons. What causes the seasons? The seasons are caused by the direction Earths axis is pointing relative to the Sun. The Earth revolves around the Sun once each year and spins on its axis of rotation once each day. This axis of rotation is tilted 23.5o relative to its plane of orbit around the Sun. The axis of rotation is pointed toward Polaris, the North Star. As the Earth orbits the Sun, the tilt of Earths axis stays lined up with the North Star. The North Pole is tilted towards the Sun and the Suns rays strike the Northern Hemisphere more directly in summer (Figure 1.2). At the summer solstice, June 21 or 22, the Suns rays hit the Earth most directly along the Tropic of Cancer (23.5o N); that is, the angle of incidence of the Suns rays there is zero (the angle of incidence is the deviation in the angle of an incoming ray from straight on). When it is summer solstice in the Northern Hemisphere, it is winter solstice in the Southern Hemisphere. Winter solstice for the Northern Hemisphere happens on December 21 or 22. The tilt of Earths axis points away from the Sun (Figure 1.3). Light from the Sun is spread out over a larger area, so that area isnt heated as much. With fewer daylight hours in winter, there is also less time for the Sun to warm the area. When it is winter in the Northern Hemisphere, it is summer in the Southern Hemisphere. Halfway between the two solstices, the Suns rays shine most directly at the Equator, called an equinox (Figure 1.4). The daylight and nighttime hours are exactly equal on an equinox. The autumnal equinox happens on September 22 or 23 and the vernal, or spring, equinox happens March 21 or 22 in the Northern Hemisphere. Summer solstice in the Northern Hemisphere. Click image to the left or use the URL below. URL:
[EX A]:
this refers to when the position of the sun is closest to one of the poles.