Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Cis-regulatory modules are non-protein-coding regions of DNA essential for the control of gene expression. One class of regulatory modules is embryonic enhancers, which drive gene expression during development as a result of transcription factor protein binding at the enhancer sequences. Recent comparative studies have begun to investigate the evolution of the sequence architecture within enhancers. These analyses are illuminating the way that developmental biologists think about enhancers by revealing their molecular mechanism of function.
Are human enhancers or promoters evolving faster?

Isova is a ruined Frankish monastery in the Peloponnese, Greece, which was built after the Fourth Crusade and inhabited by Cistercian monks.
To which religious order did Isova belong?

Sweet Sinner is a Canadian pornographic film studio, founded by pornographic actress and director Nica Noelle in 2009.

When was the inception of Sweet Sinner?