Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: Its treatment is mainly based upon discontinuation of heparin therapy.

Output: non-adverse drug event


Input: Consider Input: A case of priapism associated with trazodone is described.

Output: adverse drug event


Input: Consider Input: Central nervous system manifestations of an ibuprofen overdose reversed by naloxone.


Output: adverse drug event