Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: We presented a patient with status asthmaticus treated with a combination of theophylline and prednisone who developed a perforated gastric ulcer.
Example Output: adverse drug event

Example Input: Post-steroid septic arthritis can be treated with irrigation pump assisted arthroscopic synovectomy.
Example Output: non-adverse drug event

Example Input: METHODS: Case series consisting of 3 patients treated with rifabutin were retrospectively studied.
Example Output:
non-adverse drug event