In this task, you are given a passage which has a question and the context. You have to generate an answer to the question based on the information present in the context.

[Q]: Context: The aim of this study is to establish follow-up protocols for adult patients with common variable immunodeficiency (CVID) in a recently founded adult immunology clinic in the Central Anatolia Region of Turkey, where a clinical immunology center for adults was not available previously.', 'A total of 25 patients with CVID aged 18 years and older were included in this study. The file format consisted of 13 pages and was developed for the purpose of the study. Separate sections were designated for identity information, medical history, disease course, previous and current laboratory and imaging studies, follow-up plans, detection and management of complications/comorbidities, and treatment results.', 'The mean age of the patients was 36.6 ± 13.4 years. The delay in diagnosis was 107 ± 95.6 months. In 92% of patients, initial symptoms resulting in admission to healthcare facilities were infections. Seventeen of 25 patients (68%) had bronchiectasis at the beginning of follow-up.\Question: Does common variable immunodeficiency in adults require reserved protocols for long-term follow-up?
[A]: Early identification of complications and comorbidities in patients with CVID will significantly improve quality of life and survival. Close observation and standardized protocols for follow-up are essential components of management.


[Q]: Context: Evidence of attack-related cognitive dysfunction in migraine is growing. Controversy exists on whether cognitive dysfunction, mainly executive, may persist between attacks. Measuring the impact of cognitive function is gaining importance in clinical and research settings in migraine.', 'To compare the performance of interictal migraine patients to controls in an assembled neuropsychological battery focused on executive functions and to study the practice effect of its repeated applications.', 'Assembly of the battery that was then applied twice within 6\xa0weeks to interictal migraineurs and matched healthy controls.', 'Migraine patients (n\xa0=\xa024) and controls (n\xa0=\xa024) had similar performance in both applications of the battery. There was a slight practice effect between the first and second evaluation, significant in Stroop Interference test (P\xa0=\xa00.002, multiplicity corrected); a meaningful score change was determined for each raw test scores.\Question: Is sequential brief neuropsychological evaluation of migraineurs identical to controls?
[A]: Interictal migraineurs and controls performance is identical in a brief cognitive battery focused on executive functions. Repeated applications produced a practice effect that was quantified.


[Q]: Context: Exposure to hypoxia has been suggested to acutely alter glucose regulation. However, the effects of successive exposure to moderate hypoxia on postprandial glucose regulation and substrate oxidation pattern after multiple meals have not been elucidated.', 'We examined the effects of successive exposure to moderate hypoxia on metabolic responses and substrate oxidation pattern.', 'Eight healthy men (21.0\u2009±\u20090.6\xa0yrs, 173\u2009±\u20092.3\xa0cm, 70.6\u2009±\u20095.0\xa0kg, 23.4\u2009±\u20091.1\xa0kg/m(2)) completed two experimental trials on separate days: a rest trial under normoxic conditions (FiO2\u2009=\u200920.9%) and a rest trial under hypoxic conditions (FiO2\u2009=\u200915.0%). Experimental trials were performed over 7\xa0h in an environmental chamber. Blood and respiratory gas samples were collected over 7\xa0h. Standard meals were provided 1\xa0h (745\xa0kcal) and 4\xa0h (731\xa0kcal) after entering the chamber.', 'Although each meal significantly increased blood glucose and serum insulin concentrations (P\u2009<\u20090.05), these responses did not differ significantly between the trials. There were no significant differences in areas under the curves for glucose or insulin concentrations over 7\xa0h between the trials. No significant differences were observed in blood lactate, serum cortisol, free fatty acid, or glycerol concentrations over 7\xa0h between the trials. The oxygen consumption ( [Formula: see text]) and carbon dioxide production ( [Formula: see text]) 3\xa0h after entering the chamber were significantly higher in the hypoxic trial than in the normoxic trial (P\u2009<\u20090.05). However, the differences did not affect respiratory exchange ratio (RER). The average values of [Formula: see text], [Formula: see text], and RER did not differ between the trials.\Question: Does successive exposure to moderate hypoxia affect glucose metabolism and substrate oxidation in young healthy men?
[A]:
Seven hours of moderate hypoxia did not alter postprandial glucose responses or substrate oxidation in young healthy men.