You are given a background paragraph that describes one or more causal or qualitative relationships such as a relationship in economics or a scientific law and a story that makes use of the concepts or the relationship described in the provided paragraph. You need to come up with a question about the story that requires an understanding of the relationship described in the background paragraph. The generated question should not be answerable without both the background and story. Write a question about the story that requires a relationship in the background paragraph to answer. Check whether your question requires both the background paragraph and the story to answer. If your question can be answered by only one of these, try to rewrite your question so that it requires both. Note that "flipping" a word in the question can give rise to a new question where the answer will be different from the original question. Often, "flipping" a word gives rise to flipping the direction of the relationship, for example, from "increase" to "decrease."

Q: Background Paragraph: Excess intake of calcium may cause hypercalcaemia. However, because calcium is absorbed rather inefficiently by the intestines, high serum calcium is more likely caused by excessive secretion of parathyroid hormone (PTH) or possibly by excessive intake of vitamin D, both which facilitate calcium absorption. It may also be due to bone destruction that occurs when tumours metastasize within bone. All these conditions result in excess calcium salts being deposited in the heart, blood vessels, or kidneys. Symptoms include anorexia, nausea, vomiting, memory loss, confusion, muscle weakness, increased urination, dehydration, and metabolic bone disease. Chronic hypercalcaemia typically leads to calcification of soft tissue and its serious consequences: for example, calcification can cause loss of elasticity of vascular walls and disruption of laminar blood flow—and thence to plaque rupture and thrombosis. Conversely, inadequate calcium or vitamin D intakes may result in hypocalcaemia, often caused also by inadequate secretion of parathyroid hormone or defective PTH receptors in cells. Symptoms include neuromuscular excitability, which potentially causes tetany and disruption of conductivity in cardiac tissue. 
Story: Two sisters went in for a medical examination. Mary had normal blood calcium level, but her sister Ann sadly found out that she has a condition named hypercalcaemia. Ann started a new treatment right away.

A: Which sister didn't have an excessive secretion of parathyroid hormone (PTH)?
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Q: Background Paragraph: Another example of incomplete dominance is with sickle cell anemia, a disease in which a blood protein called hemoglobin is produced incorrectly. This causes the red blood cells to have a sickle shape, making it difficult for these misshapen cells to pass through the smallest blood vessels. A person that is homozygous recessive ( ss ) for the sickle cell trait will have red blood cells that all have the incorrect hemoglobin. A person who is homozygous dominant ( SS ) will have normal red blood cells. 
Story: Doctors studied  the blood of 2 sisters, Ann and Julie. Ann had sickle cell anemia, Julie did not.

A: Which sister had fewer cells that had a difficulty passing through the smallest blood vessels?
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Q: Background Paragraph: Earthquakes may take place every day near a volcano. But before an eruption, the number and size of earthquakes increases. This is the result of magma pushing upward into the magma chamber. This motion causes stresses on neighboring rock to build up. Eventually the ground shakes. A continuous string of earthquakes may indicate that a volcano is about to erupt. Scientists use seismographs to record the length and strength of each earthquake. 
Story: Pam and Jane were two researchers. Pam studied sedimentary rocks while Jane studied volcanoes and related phenomena, such as earthquakes.

A:
Which researcher didn't observe the number of earthquakes increasing before a volcanic eruption?
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