Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Example Input: The French Revolution broke out in 1789. At the time France was in a crisis. The government was badly run and people's lives were miserable. King Louis XIV tried to control the national parliament and raise more taxes. But his effort failed. He ordered his troops to Versailles. The people thought that Louis intended to put down the Revolution by force. On July 14, 1789, they stormed and took the Bastille, where political prisoners were kept. Ever since that day, July 14 has been the French National Day. Louis tried to flee the country in 1792, to get support from Austria and Prussia. However, he was caught and put in prison. In September 1792, the monarchy was abolished _ . In the same year, Louis was executed. A few months later his wife, Marie also had her head cut off. The Revolution of France had frightened the other kings of Europe. Armies from Austria and Prussia began to march against France. The French raised republican armies to defend the nation. The Revolution went through a period of terror. Thousands of people lost their lives. In the end, power passed to Napoleon Bonaparte.
Example Output: What's this passage about?

Example Input: Chronic myeloid leukemia (CML) is characterized by the Philadelphia translocation that fuses BCR sequences from chromosome 22 upstream of the ABL gene on chromosome 9. The chimerical Bcr-Abl protein expressed by CML cells has constitutive tyrosine kinase activity, which is essential for the pathogenesis of the disease. Imatinib, an ATP-competitive selective inhibitor of Bcr-Abl, has unprecedented efficacy for the treatment of CML. Most patients with early stage disease achieve durable complete hematological and complete cytogenetic remissions, with minimal toxicity. In contrast, responses are less stable in patients with advanced CML. This review highlights the pathogenesis of CML, its clinical features, and the development of imatinib as a specific molecularly targeted therapy. Aspects of disease monitoring and side effects are covered as well as resistance to imatinib and strategies to overcome resistance, such as alternative signal transduction inhibitors and drug combinations. Perspectives for further development are also discussed.
Example Output: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?

Example Input: What happens inside the skull of a soccer player who repeatedly heads a soccer ball? That question motivate a challenging new study of the brains of experienced players that has caused discussion and debate among soccer players, and some anxiety among those of us with soccer-playing children. For the study, researchers at the Albert Einstein College of Medicine in New York selected 34 adults,men and women. All of the volunteers had played soccer since childhood and now competed year-round in adult soccer leagues. Each filled out a detailed questionnaire developed especially for this study to determine how many times they had headed a soccer ball in the previous year, as well as whether they had experienced any known concussions in the past. Then the players completed computerized tests of their memory and other learning skills and had their brains scanned, using a complicated new MRI technique which can find structural changes in the brain that can't be seen during most scans. According to the data they presented at a Radiological Society of North America meeting last month,the researchers found that the players who had headed the ball more than about 1,100 times in the previous 12 months showed significant loss of white matter in parts of their brains involved with memory,attention and the processing of visual information, compared with players who had headed the ball fewer times. This pattern of white matter loss is "similar to those seen in traumatic brain injury" , like that after a serious concussion, the researchers reported,even though only one of these players was reported to have ever experienced a conc ussion. The players who had headed the ball about 1,100 times or more in the past year were also generally worse at recalling lists of words read to them, forgetting or _ the words far more often than players who had headed the ball less.
Example Output:
What is likely to be the cause of memory loss?