In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[Q]: Question: Which of the following covalent bonds does not appear in proteins ?: 
 Options:  <1> Phosphodiester linkage. <2> Amide link. <3> O-glucosidic bond. <4> Disulfide bond. <5> Hydrogen bond.
[A]: 1


[Q]: Question: By what legal norm were regulated for the first time the specialties for the Diploma in Nursing and obtaining the title of Specialist Nurse? 
 Options:  <1> Order June 1, 1992 (BOE June 2). <2> Royal Decree 450/2005, of April 22 (BOE May 6). <3> Royal Decree 992/1987, of July 3 (BOE 1 of August). <4> Royal Decree 943/1986 (BOE May 14). <5> Order of July 15, 1980 (BOE of July 23).
[A]: 3


[Q]: Question: Regarding enzymatic cofactors: 
 Options:  <1> All enzymes are required to be active. <2> Its binding to the enzyme is always covalent. <3> There are no two enzymes that use the same cofactor. <4> They can be metal ions. <5> They only have structural function.
[A]:
4