TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: Saturday, October 8, 120 miles northeast of Blainsworth, Nebraska; 1:16 p.m.Bob Irisin, a metrologist for the Kansas City weather bureau, is riding in his Bronco truck when he stops and radios to his friend Stan in Kansas City, that he is witnessing a sudden change in weather patterns in the area. Then a tornado suddenly touches down near a farm where Bob sees a family of a man, woman and their little girl standing in front of the house, unaware of the tornado approaching behind them. Bob drives as near as he can go and manages to yell out a warning to the family seconds before they see the twister coming. The family runs into their storm shelter just in time before the twister destroys their house. Bob drives away from harms way just in time.Meanwhile, in Blainsworth, there is the annual fall Bike-a-thon race for the high school kids. 13-year-old Dan Hatch gets a flat tire and doesnt come in at all. Dans stern father, Jack, is arguing with a banker who's asking to foreclose on his hardware shop since a new mall has opened in the nearby town. Jack refuses to sell the shop at any price. Dan walks his bike into the town square where his best friend, Arthur, talks with him about getting "crashed and burned" during the race. Jack walks over and becomes hard on Dan for not finishing the race like a man should. Dan yells at his father for being so demanding and that he can't expect anything from anyone. Dan's mother, Laura, with her new baby Ryan and her friend Jenny, walk by and never less tell him he did okay anyway. Just then, Dan is called to the square podium for he is has been chosen by a lottery to be the winner of a new Schwinn Voyager bicycle, much to his father and mother's delight.75 miles northeast of Blainsworth; 3:37 p.m. Bob sits in his Bronco truck and radios in of rogue weather patterns, while observing another tornado rip through a nearby trailer park. Bob tells Stan that the front is moving south instead of north and the atmospheric activity is the most bizarre he has ever seen. Bob decides to travel to Blainsworth to see if anything will happen.Outside of Blainsworth, Dan and Arthur sit in the woods looking up at the clear sky. Dan tell Arthur about his fathers demanding which is a driving force that he cant stand. Then Arthur's two younger sisters, Stacey and Ronnie Vae, appear and want Arthur to come home since their parents are out of town for the weekend. Arthur and Dan watch as clouds begin to roll in and they decide to get indoors. At Arthurs house, the boys play a game of pool, in which Dan forgets he's suppose to take his grandmother's dog for a walk.Six miles northeast of Blainsworth 4:30 p.m.; Dan arrives at his grandmother Goldie's house where his father is already there taking her dog to the vet, for it has a bad leg. Jack yells at Dan for not being responsible for anything, and Dan rides on his new bike home.Arthur arrives at the Hatch house, were Laura is getting ready to leave for work for the evening. Jenny arrives at the house to pick Laura up, were they talk about Jack being so domineering on Dan for he doesn't want Dan to end up a loser like him.Nightfall. Arthur and Dan play with musical instruments, while checking every few minutes if baby Ryan in the next room is all right. Jack then arrives and tells Dan and Arthur to bring their bicycles in for its raining. Going out, they find that its raining hard and the winds are picking up speed. Arthur tells Dan that since hes originally from Los Angeles, he enjoys the rain, while Dan sees little amusement in it, for he tells Arthur that rain and hailstorms can get bad.At the local diner in town, Laura is waitressing when Bob walks in asking for some coffee. Bob overhears a farmer named Gus talk about the storm and of tornados reported in the area. Bob tells Gus that most people killed by tornados

SOLUTION: What kind of race does Jack push Danny to compete in?

PROBLEM: SET domain methyltransferases deposit methyl marks on specific histone tail lysine residues and play a major role in epigenetic regulation of gene transcription. We solved the structures of the catalytic domains of GLP, G9a, Suv39H2 and PRDM2, four of the eight known human H3K9 methyltransferases in their apo conformation or in complex with the methyl donating cofactor, and peptide substrates. We analyzed the structural determinants for methylation state specificity, and designed a G9a mutant able to tri-methylate H3K9. We show that the I-SET domain acts as a rigid docking platform, while induced-fit of the Post-SET domain is necessary to achieve a catalytically competent conformation. We also propose a model where long-range electrostatics bring enzyme and histone substrate together, while the presence of an arginine upstream of the target lysine is critical for binding and specificity. This article can also be viewed as an enhanced version in which the text of the article is integrated with interactive 3D representations and animated transitions. Please note that a web plugin is required to access this enhanced functionality. Instructions for the installation and use of the web plugin are available in Text S1.

SOLUTION: What is the characteristic domain of histone methyltransferases?

PROBLEM: The Grandes etudes de Paganini, S. 141, are a series of six etudes for the piano by Franz Liszt, revised in 1851 from an earlier version (published as Etudes d'execution transcendante d'apres Paganini, S.140, in 1838).

SOLUTION:
On which instrument(s) was Grandes études de Paganini created to be played on?