In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Example Input: Question: The increase in standard free energy of ATP hydrolysis depends, among others, on the following structural characteristic: 
 Options:  <1> Its polar character. <2> Its amphipathic nature <3> Its stabilization by resonance. <4> Of the phosphoryl group number it contains. <5> Of the cation with which the soluble salt forms.
Example Output: 3

Example Input: Question: The probability that a person free of a disease develops it during a period of time, corresponds to: 
 Options:  <1> Chance. <2> Prevalence <3> Specificity <4> Forecast. <5> Risk.
Example Output: 5

Example Input: Question: Which of the following clinical situations carries a greater risk of progression of chronic kidney disease and would require more strict control by the nephrologist? 
 Options:  <1> Diabetic patient with a glomerular filtration rate of 46 mL / min and a urine albumin / creatinine ratio of 25 mg / g. <2> Diabetic patient with a glomerular filtration rate of 89 mL / min and urine albumin / creatinine ratio of 475 mg / g. <3> Hypertensive patient with glomerular filtration rate of 65 mL / min and urine albumin / creatinine ratio of 150 mg / g. <4> A 70-year-old hypertensive patient with 1 simple cyst in each kidney, a glomerular filtration rate of 35 mL / min and an albumin / creatinine ratio in urine of 10 mg / g. <5> An 87-year-old hypertensive patient with a glomerular filtration rate of 30 mL / min and a urine albumin / creatinine ratio of 5 mg / g.
Example Output:
2