Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Ex Input:
Context: The War of Jenkins' Ear was a conflict between Britain and Spain lasting from 1739 to 1748, with major operations largely ended by 1742. Its unusual name, coined by Thomas Carlyle in 1858, refers to an ear severed from Robert Jenkins, a captain of a British merchant ship. There is no evidence of the stories that the severed ear was exhibited before the British Parliament. The seeds of conflict began with the separation of an ear from Jenkins following the boarding of his vessel by Spanish coast guards in 1731, eight years before the war began. Popular response to the incident was tepid until several years later when opposition politicians and the British South Sea Company hoped to spur outrage against Spain, believing that a victorious war would improve Britain's trading opportunities in the Caribbean. Also ostensibly providing the impetus to war against the Spanish Empire was a desire to pressure the Spanish not to renege on the lucrative asiento contract, which gave British slavers permission to sell slaves in Spanish America. The war resulted in heavy British casualties in North America. After 1742, the war was subsumed by the wider War of the Austrian Succession, which involved most of the powers of Europe. Peace arrived with the Treaty of Aix-la-Chapelle in 1748. From the British perspective, the war was notable because it was the first time that a regiment of colonial American troops was raised and placed "on the Establishment" - made a part of the regular British Army - and sent to fight outside North America. 
 Question: When did the wider War of the Austrian Succession end?

Ex Output:
1748


Ex Input:
Context: Today, nearly 400 animals are listed as threatened or endangered animals in the United States. Many are at risk of becoming extinct or disappearing permanently. Unless efforts to save these vulnerable animals succeed, many of the country's greatest creatures will be lost forever. From the facts listed, guess which animals are endangered. Click on the picture to find out more about each of these animals in trouble. American Crocodile *American crocodiles are about 12 feet long. They live on land and in shallow water, swamps and marshes. *American crocodiles like to float in the water with only their eyes and noses above the water surface. *American crocodiles eat mostly small animals, which they grab with their strong jaws and sharp teeth. *American crocodiles lay eggs. They hide their eggs under twigs and leaves, or bury them in the sand. *Some crocodiles help their young hatch, and then carry them to the water in their mouth. Habitat Southern Florida, Mexico, Central and South American, Caribbean islands. Why It's Endangered Overhunted for its skin and habitat destruction. Peninsular Bighorn Sheep *Bighorn sheep can weigh as much as 280 pounds and stand about 3 feet tall. *They live in dry, desert mountain ranges, near rocky cliffs. *Bighorn sheep eat grass, twigs and leaves. *Male sheep are called rams and can be recognized by their huge, brown horns. The horns curl back over the ears, down,and up past the cheeks. *They live in herds or groups. The male sheep with the biggest horns are usually in charge. Male horns can weigh as much as 30 pounds. *Males will use their massive horns to fight. The fights can last as long as 24 hours. *Females are called ewes. They are smaller than rams and have shorter, smaller horns. Habitat Nevada and California to west Texas and south into Mexico. Why It's Endangered Loss of habitat, hunting illegally, drought and disease. 
 Question: Where can we find both American crocodiles and Bighorn sheep according to the passage?

Ex Output:
mexico.


Ex Input:
Context: Mutations in the ribosomal protein S19 gene (RPS19) have been found in 25% of patients with Diamond-Blackfan anemia, a rare syndrome of congenital bone marrow failure characterized by erythroblastopenia and various malformations. Mechanistic understanding of the role of RPS19 in normal erythropoiesis and in the Diamond-Blackfan anemia defect is still poor. However, defective ribosome biogenesis and, in particular, impaired 18S ribosomal RNA maturation have been documented in association with various identified RPS19 mutations. Recently, new genes, all encoding ribosomal proteins, have been found to be mutated in Diamond-Blackfan anemia, adding further support to the concept that ribosome biogenesis plays an important role in regulating erythropoiesis. We previously showed variability in the levels of expression and subcellular localization of a subset of RPS19 mutant proteins. To define the mechanistic basis for this variability better, we studied a large number of mutant proteins and characterized both RPS19 expression level using a specific antibody against RPS19 and RPS19 subcellular localization after transfection of Cos-7 cells with various green fluorescent protein-RPS19 mutants. To investigate the role of the proteasome in RPS19 degradation, we examined the effect of various proteasome inhibitors, namely lactacystin, MG132, and bortezomib on RPS19 expression and subcellular localization We found two distinct classes of RPS19 protein defects in Diamond-Blackfan anemia based on the stability of the mutant proteins: (i) slightly decreased to normal levels of expression and normal nucleolar localization and (ii) markedly deficient expression and failure to localize to the nucleolus. All the proteasome inhibitors tested were able to restore the expression levels and normal subcellular localization of several unstable mutant proteins. Our findings demonstrate an important role for the proteasomal degradation pathway in regulating the expression levels and nucleolar localization of certain mutant RPS19 proteins in Diamond-Blackfan anemia. 
 Question: In which syndrome is the RPS19 gene most frequently mutated?

Ex Output:

dba