Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[Q]: Imatinib was the first BCR-ABL tyrosine kinase inhibitor to become clinically available. In this study, we retrospectively evaluated the long-term efficacy of low-dose imatinib (final maintenance dose <300mg per day) due to intolerance, in comparison to optimal-dose imatinib (300mg per day) in patients with Philadelphia chromosome-positive chronic myeloid leukemia in the chronic phase. The Kaplan-Meier estimates of the median time to complete cytogenetic response, major molecular response, and complete molecular response were longer for 31 patients receiving low-dose imatinib (360, 1360, and 1420days, respectively) than 74 patients receiving optimal-dose imatinib (170, 420, and 720days, respectively). However, the differences in response shrank over time and progression-free survival were comparable between the two groups. These findings suggest that long-term treatment with low-dose imatinib is an acceptable alternative for patients with intolerance to the optimal dose.
[A]: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?


[Q]: Yana De Leeuw (born 6 September 1990) is a Belgian female former volleyball player, playing as a setter.
[A]: Which sex or gender can Yana De Leeuw be described as?


[Q]: Diabolical Streak is the second studio album by American Neo-Cabaret artist Jill Tracy, released in 1999.
[A]:
What label was responsible for Diabolical Streak?