TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Is early systemic sclerosis : serum profiling of factors involved in endothelial , T-cell , and fibroblast interplay marked by elevated interleukin-33 levels?
Answer: Our study suggests that an endothelial, T-cell and fibroblast activation can be present in patients with early SSc and it is associated with a distinct profile of circulating factors involved in the cross-talk of these cells. The marked increase of IL-33 in early SSc patients suggests new routes of investigation of cell-cell dynamics in target tissues predating overt disease manifestations, thus opening to new therapeutic approaches.

SOLUTION: yes

PROBLEM: Question: Does vitamin E supplementation alter physiological performance at fixed blood lactate concentrations in trained runners?
Answer: Daily VE supplementation for 35 days does not enhance or impair physiological performance at fixed blood lactate concentrations. Long-term VE supplementation for the purposes of performance enhancement is not recommended.

SOLUTION: no

PROBLEM: Question: Is body mass index independently associated with increased aortic stiffness in a Brazilian population?
Answer: In conclusion, our study failed to provide evidence of a positive, blood pressure (BP)-independent association between obesity on aortic stiffness. Our data suggests that the previously reported finding of an association between obesity and aortic stiffness was probably confounded by the progressive increase in BP observed in obesity.

SOLUTION:
no