TASK DEFINITION: Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.
PROBLEM: It is generally accepted that the mitochondria play central roles in energy production of most eukaryotes. In contrast, it has been thought that Plasmodium spp., the causative agent of malaria, rely mainly on cytosolic glycolysis but not mitochondrial oxidative phosphorylation for energy production during blood stages. However, Plasmodium spp. possesses all genes necessary for the tricarboxylic acid (TCA) cycle and most of the genes for electron transport chain (ETC) enzymes. Therefore, it remains elusive whether oxidative phosphorylation is essential for the parasite survival. To elucidate the role of TCA metabolism and ETC in malaria parasites, we deleted the gene for flavoprotein (Fp) subunit, Pbsdha, one of four components of complex II, a catalytic subunit for succinate dehydrogenase activity. The Pbsdha(-) parasite grew normally at blood stages in mouse. In contrast, ookinete formation of Pbsdha(-) parasites in the mosquito stage was severely impaired. Finally, Pbsdha(-) ookinetes failed in oocyst formation, leading to complete malaria transmission blockade. These results suggest that malaria parasite may switch the energy metabolism from glycolysis to oxidative phosphorylation to adapt to the insect vector where glucose is not readily available for ATP production.

SOLUTION: Which is the causative agent of malaria?

PROBLEM: In late 1911, she worked as a secretary for Sun Yat-sen, a job later succeeded by her sister, Soong Ching-ling, who later became Madame Sun Yat-sen. Soong Ai-ling met her future husband, Kung Hsiang Hsi, in 1913, and married the following year in Yokohama.

SOLUTION: Which woman was the sister of Soong Ai-ling?

PROBLEM: Rochester Cathedral, formally the Cathedral Church of Christ and the Blessed Virgin Mary, is an English church of Norman architecture in Rochester, Medway.

SOLUTION:
The art style of Rochester Cathedral is what?