In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[Q]: Question: The main method for the preparation of βceto esters is the reaction known as: 
 Options:  <1> Malonic synthesis <2> Acetoacetic synthesis. <3> Condensing of Claisen. <4> Perkin reaction. <5> Hofmann reaction.
[A]: 3


[Q]: Question: A 55-year-old woman with adrenal insufficiency has been prescribed corticosteroid treatment. Which of the following instructions would you provide in relation to this treatment? 
 Options:  <1> Take the drug first thing in the morning. <2> Take the drug before bedtime. <3> Exclude foods rich in calcium and vitamin D from the diet. <4> Eat a diet low in calories and protein. <5> Monitor the decrease in blood pressure.
[A]: 1


[Q]: Question: Regarding gastroesophageal reflux disease, which of the following statements is true? 
 Options:  <1> The intensity and frequency of heartburn has little relationship with the presence and severity of endoscopic esophagitis. <2> Most patients with gastroesophageal reflux disease have esophagitis at endoscopy. <3> Treatment with proton pump inhibitors usually achieves good control of symptoms but is not superior to placebo in the endoscopic cure of esophagitis. <4> Barrett's esophagus can progress to low-grade epithelial dysplasia, high-grade epithelial dysplasia, and finally squamous cell carcinoma of the esophagus. <5> Endoscopic screening and surveillance programs have unequivocally shown to be able to reduce mortality in patients with Barrett's esophagus.
[A]:
1