TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Is a gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity associated with familial Inappropriate Sinus Tachycardia?
Answer: This is the first report of a gain-of-function HCN4 mutation associated with IST through increased sensitivity to cAMP-dependent activation.

SOLUTION: yes

PROBLEM: Question: Does leukocyte concentration and composition in platelet-rich plasma ( PRP ) influence the growth factor and protease concentrations?
Answer: These findings demonstrate that leukocytes strongly influence the quality of PRPs. Therefore, modifying the PRP preparation method according to the pathology is essential to achieve better clinical results with PRP therapy.

SOLUTION: yes

PROBLEM: Question: Is human endogenous retrovirus with a high genomic sequence homology with IDDMK ( 1,2 ) 22 specific for Type I ( insulin-dependent ) diabetic patients but ubiquitous?
Answer: We conclude that a human endogenous retroviral gene with high sequence homology with IDDMK(1,2)22 is not specific for diabetic patients but, rather, is ubiquitous.

SOLUTION:
no