In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

 Although interleukin ( IL ) - 12 and IL - 4 polarize naive CD4 ( + ) T cells toward T helper cell type 1 ( Th1 ) or Th2 phenotypes , it is not known whether cytokines instruct the developmental fate in uncommitted progenitors or select for outgrowth of cells that have stochastically committed to a particular fate .
IL - 4

 We describe a novel and potentially important mechanism of nitric oxide signaling - through direct activation of guanine nucleotide - binding proteins ( G proteins ) .
G proteins

 PC - PLC - activated hydrolysis of PC was found to induce bona fide p50 / p65 NF - kappa B binding activity in three different cell lines of human or murine origin .

PC - PLC