Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Example Input: Context: Chronic lymphocytic leukemia (CLL) cells depend on microenvironmental factors for proliferation and survival. In particular, the B-cell receptor (BCR) and nuclear factor- B (NF-B) pathways are activated in the lymph node (LN) microenvironment. Thus, model systems mimicking tumor-host interactions are important tools to study CLL biology and pathogenesis. We investigated whether the recently established NOD/scid/c(null) (NSG) mouse xenograft model can recapitulate the effects of the human microenvironment. We assessed, therefore, tumor characteristics previously defined in LN-resident CLL cells, including proliferation, and activation of the BCR and NF-B pathways. We found that the murine spleen (SP) microenvironment supported CLL cell proliferation and activation to a similar degree than the human LN, including induction of BCR and NF-B signaling in the xenografted cells. Next, we used this model to study ibrutinib, a Bruton's tyrosine kinase inhibitor in clinical development. Ibrutinib inhibited BCR and NF-B signaling induced by the microenvironment, decreased proliferation, induced apoptosis and reduced the tumor burden in vivo. Thus, our data demonstrate that the SP of xenografted NSG mice can, in part, recapitulate the role of the human LN for CLL cells. In addition, we show that ibrutinib effectively disrupts tumor-host interactions essential for CLL cell proliferation and survival in vivo. 
 Question: What is the name of Bruton's tyrosine kinase inhibitor that can be used for treatment of chronic lymphocytic leukemia?
Example Output: ibrutinib

Example Input: Context: Did you ever make a secret code? One way to make a code is to represent each letter of the alphabet by a different number. Then you can send a coded message by writing words as strings of digits. This is similar to how information is encoded using an electric current. The voltage of the current is changed rapidly and repeatedly to encode a message, called an electronic signal. There are two different types of electronic signals: analog signals and digital signals. Both are illustrated in Figure 23.20. A digital signal consists of pulses of voltage, created by repeatedly switching the current off and on. This type of signal encodes information as a string of 0s (current off) and 1s (current on). This is called a binary ("two-digit") code. DVDs, for example, encode sounds and pictures as digital signals. An analog signal consists of continuously changing voltage in a circuit. For example, microphones encode sounds as analog signals. Electronic components are the parts used in electronic devices such as computers. The components transmit and change electric current. They are made of materials called semiconductors. A semiconductor is a solid crystalusually consisting mainly of siliconthat can conduct current better than an electric insulator but not as well as an electric conductor. Very small amounts of other elements, such as boron or phosphorus, are added to the silicon so it can conduct current. A semiconductor is illustrated in Figure 23.21. There are two different types of semiconductors: n-type and p-type. An n-type semiconductor consists of silicon and an element such as phosphorus that gives the silicon crystal extra electrons. An n-type semiconductor is like the negative terminal in a chemical cell. A p-type semiconductor consists of silicon and an element such as boron that gives the silicon positively charged holes where electrons are missing. A p-type semiconductor is like the positive terminal in a chemical cell. Electronic components contain many semiconductors. Types of components include diodes, transistors, and inte- grated circuits. Each type is described in Table 23.2. Electronic Component Diode Transistor Integrated Circuit (Microchip) Description A diode consists of a p-type and an n-type semicon- ductor placed side by side. When a diode is connected by leads to a source of voltage, electrons flow from the n-type to the p-type semiconductor. This is the only direction that electrons can flow in a diode. This makes a diode useful for changing alternating current to direct current. A transistor consists of three semiconductors, either p- n-p or n-p-n. Current cant flow through a transistor unless a small amount of current is applied to the center semiconductor (through the base). Then a much larger current can flow through the transistor from end to end (from collector to emitter). This means that a transmitter can be used as a switch, with pulses of a small current turning a larger current on and off. A transistor can also be used to increase the amount of current flowing through a circuit. You can learn more about transistors and how they work at this URL: http An integrated circuitalso called a microchipis a tiny, flat piece of silicon that consists of layers of elec- tronic components such as transistors. An integrated circuit as small as a fingernail can contain millions of electronic components. Current flows extremely rapidly in an integrated circuit because it doesnt have far to travel. You can learn how microprocessors are made at this URL: Many of the devices you commonly use are electronic. Electronic devices include computers, mobile phones, TV remotes, DVD and CD players, game systems, MP3 players, and digital cameras. All of these devices use electric current to encode, analyze, or transmit information. Consider the computer as an example of an electronic device. A computer contains microchips with millions of tiny electronic components. Information is encoded as 0s and 1s and transmitted as electrical pulses. One digit (either 0 or 1) is called a bit, which stands for "binary digit." Each group of eight digits is called a byte. A gigabyte is a billion bytes that 
 Question: tiny flat piece of silicon that contains layers of many electronic components
Example Output: integrated circuit

Example Input: Context: After two close losses the Rams hoped to bounce back at the Edward Jones Dome for their first win of the season. On the first possession the Rams drove down the field and capped off their drive with a 41-yard touchdown run by Steven Jackson. On the ensuing Redskins drive, Donovan McNabb drove into Rams territory before Na'il Diggs forced a fumble on Santana Moss. James Butler, who was playing for an injured Craig Dahl picked up the fumbled and returned it 49yards before being forced out of bounds. Bradford threw a three-yard touchdown pass to Daniel Fells to make the score 14-0. The Redskins tried to start their offense again, but after being stopped on third down had to punt. Graham Gano's punt was blocked however by Rams rookie wide receiver Dominique Curry, and the Rams took over in striking distance for another touchdown. Sam Bradford threw his first interception of the day, and the Redskins were able to take over again, and were able to score a field goal. On the kickoff after the Redskins field goal, Mardy Gilyard, the Rams rookie kick returner/wide receiver fumbled the ball, and the Redskins took over on the 21yard line. Donovan McNabb hit Santana Moss for a touchdown the next play. Steven Jackson was injured on the next drive for the Rams, and the Rams were unable to score. The next drive the Redskins kicked another field goal to make the score 13-14. The Rams marched down the field one last time, but were stalled in the redzone. With 31seconds left Josh Brown attempted a field goal, but the Redskins blocked the kick and at the half the Rams led 14-13. At the start of the second half, McNabb hit Moss for a 56-yard pass. The Rams kept the Redskins out of the endzone, and Washington settled for the go ahead field goal to make the score 16-14. The next drive St. Louis marched down the field, and Kenneth Darby, playing for an injured Steven Jackson scored his first TD of the year from 12yards out to make the score 21-16. Redskins were unable to score during the fourth quarter however, and McNabb was picked off by Bradly Fletcher as he attempted a comeback. Josh Brown kicked three field goals in the final quarter to seal the Rams first victory of the year with a score of 30-16, snapping a 13-game home losing skid. This win also marked their highest scoring performance in a regular season game since their 34-14 victory over the Dallas Cowboys on October 19, 2008. 
 Question: What team scored the first touchdown of the game?
Example Output:
rams