TASK DEFINITION: In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
PROBLEM: Question: The BRCA-1 gene mutation is associated with a high risk of: 
 Options:  <1> Acute myocardial infarction. <2> Breast cancer <3> Alzheimer disease. <4> Parkinson's disease <5> Tay-Sach disease.

SOLUTION: 2

PROBLEM: Question: In general, water intake should be increased in patients undergoing chemotherapy with the aim of: 
 Options:  <1> Prevent kidney damage. <2> Fluidify bronchial secretions. <3> Relieve post-chemotherapy nausea. <4> Increase the volume. <5> Decrease the risk of infection.

SOLUTION: 1

PROBLEM: Question: Enzymatic regulation by reversible covalent modification: 
 Options:  <1> It involves the breaking of the peptide bond. <2> It requires the action of another enzyme. <3> It always involves phosphorylation reaction. <4> It never affects allosteric enzymes. <5> The enzyme never comes in two forms.

SOLUTION:
2