In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[EX Q]: Question: Esters can be obtained from carboxylic acids and alcohols, by applying the Fischer esterification reaction in which: 
 Options:  <1> A base is used as a catalyst. <2> A ketone is used as the solvent. <3> A reducing reagent is used. <4> An oxidizing agent is used. <5> Acid catalysis is used.
[EX A]: 5

[EX Q]: Question: What is interpersonal therapy of social rhythm (or interpersonal and social rhythm therapy)? 
 Options:  <1> An adaptation of interpersonal therapy to the treatment of dysthymic disorder. <2> An adaptation of interpersonal therapy to the treatment of severe major depressive disorder. <3> A therapy resulting from combining interpersonal therapy, behavioral activation therapy and social problem solving therapy. <4> An adaptation of interpersonal therapy for patients with major depressive disorder who have serious problems in their social relationships. <5> An adaptation of interpersonal therapy to the treatment of bipolar disorder.
[EX A]: 5

[EX Q]: Question: What is the biosynthetic route of terpenes in plants ?: 
 Options:  <1> They are synthesized by the mevalonic acid route or by the fatty acid route. <2> They are synthesized by the mevalonic acid route or by the deoxy-xylulose phosphate (DOXP) pathway also called GAP / Pyruvate. <3> They are synthesized by the mevalonic route and the sikimico route. <4> They are synthesized by the sikimic acid route or by the deoxy-xylulose phosphate (DOXP) pathway also called GAP / Pyruvate. <5> They are synthesized by the polyacetate route.
[EX A]:
2