This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

Example Input: Serotonin is a neuromodulator involved in regulation of mood and behavior. Development in the limbic system plays an important role in determining rewards and punishments and processing emotional experience and social information. Changes in the levels of the neurotransmitters dopamine and serotonin in the limbic system make adolescents more emotional and more responsive to rewards and stress. The corresponding increase in emotional variability also can increase adolescents' vulnerability. The effect of serotonin is not limited to the limbic system: Several serotonin receptors have their gene expression change dramatically during adolescence, particularly in the human frontal and prefrontal cortex .
Example Output: Which neuromodulator is involved in regulation of mood and behavior?

Example Input: Tibet retained nominal power over religious and regional political affairs, while the Mongols managed a structural and administrative rule over the region, reinforced by the rare military intervention. This existed as a "diarchic structure" under the Yuan emperor, with power primarily in favor of the Mongols. Mongolian prince Khuden gained temporal power in Tibet in the 1240s and sponsored Sakya Pandita, whose seat became the capital of Tibet. Drogön Chögyal Phagpa, Sakya Pandita's nephew became Imperial Preceptor of Kublai Khan, founder of the Yuan dynasty.
Example Output: Who managed religious and regional political affairs?

Example Input: Theoretical analyses show that detours that increase flight distance by up to 20% will often be adaptive on aerodynamic grounds - a bird that loads itself with food to cross a long barrier flies less efficiently. However some species show circuitous migratory routes that reflect historical range expansions and are far from optimal in ecological terms. An example is the migration of continental populations of Swainson's thrush Catharus ustulatus, which fly far east across North America before turning south via Florida to reach northern South America; this route is believed to be the consequence of a range expansion that occurred about 10,000 years ago. Detours may also be caused by differential wind conditions, predation risk, or other factors.
Example Output:
What percentage increase in flight distance will often be adaptive?