In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Example Input: Question: Esters can be obtained from carboxylic acids and alcohols, by applying the Fischer esterification reaction in which: 
 Options:  <1> A base is used as a catalyst. <2> A ketone is used as the solvent. <3> A reducing reagent is used. <4> An oxidizing agent is used. <5> Acid catalysis is used.
Example Output: 5

Example Input: Question: In relation to the hearing and balance processes, indicate which statement is correct: 
 Options:  <1> The sounds are perceived in the organ of Corti and the balance in ampullary crests and maculae. <2> The auditory signal is processed in the cerebellum. <3> The inner ear is full of air. <4> Otoliths are composed of quartz. <5> All answers are false.
Example Output: 1

Example Input: Question: In IgE-mediated hypersensitivity reactions: 
 Options:  <1> Eosinophils and mast cells play an important role. <2> There are no cellular elements involved. <3> Antibody-mediated cytotoxicity reactions play a key role. <4> There are no elements of the immune system involved in atopy. <5> The IgE immunoglobulin receptor does not intervene.
Example Output:
1