This task is about creating an unanswerable question based on a given passage. Construct a question that looks relevant to the given context but is unanswerable. Following are a few suggestions about how to create unanswerable questions:
(i) create questions which require satisfying a constraint that is not mentioned in the passage
(ii) create questions which require information beyond what is provided in the passage in order to answer
(iii) replace an existing entity, number, date mentioned in the passage with other entity, number, date and use it in the question
(iv) create a question which is answerable from the passage and then replace one or two words by their antonyms or insert/remove negation words to make it unanswerable.

Passage: The Rhine was not known to Herodotus and first enters the historical period in the 1st century BC in Roman-era geography. At that time, it formed the boundary between Gaul and Germania. The Upper Rhine had been part of the areal of the late Hallstatt culture since the 6th century BC, and by the 1st century BC, the areal of the La Tène culture covered almost its entire length, forming a contact zone with the Jastorf culture, i.e. the locus of early Celtic-Germanic cultural contact. In Roman geography, the Rhine formed the boundary between Gallia and Germania by definition; e.g. Maurus Servius Honoratus, Commentary on the Aeneid of Vergil (8.727) (Rhenus) fluvius Galliae, qui Germanos a Gallia dividit "(The Rhine is a) river of Gaul, which divides the Germanic people from Gaul."
When did Herodotus discover the Rhine?

Passage: Thermodynamics divides energy transformation into two kinds: reversible processes and irreversible processes. An irreversible process is one in which energy is dissipated (spread) into empty energy states available in a volume, from which it cannot be recovered into more concentrated forms (fewer quantum states), without degradation of even more energy. A reversible process is one in which this sort of dissipation does not happen. For example, conversion of energy from one type of potential field to another, is reversible, as in the pendulum system described above. In processes where heat is generated, quantum states of lower energy, present as possible excitations in fields between atoms, act as a reservoir for part of the energy, from which it cannot be recovered, in order to be converted with 100% efficiency into other forms of energy. In this case, the energy must partly stay as heat, and cannot be completely recovered as usable energy, except at the price of an increase in some other kind of heat-like increase in disorder in quantum states, in the universe (such as an expansion of matter, or a randomisation in a crystal).
Thermodynamics multiplies energy information into what two kinds?

Passage: The development of new technologies has made it dramatically easier and cheaper to do sequencing, and the number of complete genome sequences is growing rapidly. The US National Institutes of Health maintains one of several comprehensive databases of genomic information. Among the thousands of completed genome sequencing projects include those for rice, a mouse, the plant Arabidopsis thaliana, the puffer fish, and the bacteria E. coli. In December 2013, scientists first sequenced the entire genome of a Neanderthal, an extinct species of humans. The genome was extracted from the toe bone of a 130,000-year-old Neanderthal found in a Siberian cave.

What has extracting genes from a Neanderthal made it easier for scientists to do?