Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
Our series of 3 patients supports a causal connection between bleomycin and scleroderma.

Ex Output:
adverse drug event


Ex Input:
We report a case of hepatolithiasis (intrahepatic stone) complicated by gram-negative sepsis in a 37 year old male with acromegaly being treated with octreotide.

Ex Output:
adverse drug event


Ex Input:
The nephrotic syndrome developed in a patient receiving therapy with gold for rheumatoid arthritis.

Ex Output:

adverse drug event