instruction:
In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.
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Background: Kawasaki disease (KD) becomes one of the common diseases in Korea. Changes in clinical features and laboratory findings of KD were evaluated over a period of 10 years. Methods: We reviewed the medical records of KD patients and compared the clinical and laboratory features of two KD patient groups: those admitted from 2000 to 2004 (group A, 284 cases) and those admitted from 2010 to 2014 (group B, 331 cases). Results: There were a total of 615 KD patients (mean age: 29.7 months; male-to-female ratio = 1.6:1), including 228 incomplete KD patients. Incomplete KD patients had milder values in some laboratory indices. The preadmission and total fever durations were longer in group A than in group B. The proportion of incomplete KD was higher in group B, but incidence of coronary artery lesions (CALs) was lower. For laboratory indices, the C-reactive protein and follow-up platelet values were lower, and the hemoglobin and albumin values were higher in group B. The same clinical and laboratory findings were confirmed in the KD subgroups; those with the same fever duration of 5 or 6 days and same ages, those with complete KD, and those with incomplete KD in the two different time periods. Conclusions: Our findings suggest that clinical features of KD tend to be milder over time and manifest in a higher incidence of incomplete KD, lower incidence of CALs, and less severe laboratory findings in recent KD patients in Korea compared with their historic counterparts.
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Changes in clinical and laboratory features of Kawasaki disease noted over time in Daejeon, Korea


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Public health measures employed to fight against the spread of SARS need to be guided by biomedical knowledge as well as an understanding of the social science aspects of the disease. Using Singapore as a case study, we explore how the state constructs the disease and implements measures targeted at creating a ring of defense around the island and using surveillance to monitor and prevent its spread. While there is support, there is also resentment among some Singaporeans who complain that their right to privacy has been invaded and that over surveillance may have actually occurred. Marginalisation and discrimination have not only affected the local population but in this open economy which is striving to achieve global city status, businesses, tourism, foreign talent, foreign contract workers and foreign students studying in Singapore have also been negatively affected. While Singapore has been applauded by WHO and used as an example of quick and effective response, a holistic approach to the management of infectious disease must address the social implications of strategies that are drawn from medical knowledge alone because it impinges on the social lives of people and how people interact with each other under stressful circumstances.
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SARS in Singapore: surveillance strategies in a globalising city


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A persistent infection by human coronavirus 229E (HCV/229E) was established in a human continuous cell line (L 132). Following the initial infection with stock HCV/229E, several cultures were established of which two (HV t and IIV4) have been maintained by continous passage for two years. These eultures have shed high titres of infectious virus continuously into the supernatant fluid since their initiation. The persistently infected ceils were resistant to homologous superinfection but supported polio virus replication to normal titres. Preliminary tests indicated that 50--100 percent of the cells contain virus. Neither interferon nor reverse transeriptase could be detected in these cultures and the presence of defective interfering particles could not be demonstrated. VH t and V H 4 coronaviruses, isolated from these persistently infected cultures (HV) and identified by 229E antiserum neutralization, were more eytoeidal than the parent virus as judged by plaque characteristics and CPE however, they were indistinguishable on the basis of density, EM morphology, a.nd genome size. Present evidence indicates that temperature plays an important but as yet undetermined role in the establishment and maintenance of stable 229 E persistently infected cell cultures. 0304-8608/81/0069/0117/$02.60 6, 128--132 (1975/76).
answer:

Archives of Virology Establishment and Maintenance of a Persistent Infection of L 132 Cells by Human Coronavirus Strain 229E