Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: We report a case of acne fulminans occurring during treatment with 13-cis-retinoic acid for cystic acne.
Example Output: adverse drug event

Example Input: CASE SUMMARY: A 66-year-old man with a background history of breast carcinoma was admitted with pleuritic chest pain.
Example Output: non-adverse drug event

Example Input: There are no previous reports in the literature about the emergence of CML during treatment with hydroxyurea.
Example Output:
adverse drug event