Given a passage classify if the passage has a definite objective/aim/goal or not. Output '1' if the passage has a defininte objective/aim/goal and output '0' if the passage does not have a definite objective/aim/goal.

Example Input: Migraine is associated with epilepsy, but the time order and nature of the relationship are unclear. We conducted a population based case control study to clarify the time order to determine whether migraine is a risk factor for epilepsy.', 'Migraine symptoms were evaluated in a population-based case-control study of all incident epilepsy in Icelandic children and in matched controls (next two same sex births in the country).', 'Migraine was associated with a fourfold increased risk for developing epilepsy, an association explained by migraine with aura (odds ratio, 8.1; 95% confidence interval, 2.7-24.3). Migraine without aura did not increase risk for epilepsy.
Example Output: 1

Example Input: Although allergic sensitization can be generated against various allergens, it is unknown how such a diversity of antigens is able to promote TH2-mediated inflammation leading to atopy. Our previous studies demonstrated that allergen-specific IgG immune complexes (ICs) and house dust mite (HDM) extract both induced dendritic cells (DCs) to drive TH2-mediated inflammation, but the mechanism by which these diverse stimuli produce similar responses is unknown.', 'We sought to identify the DC signaling pathways used by TH2 stimuli to promote TH2-mediated inflammation.', 'C57BL/6, FcγRIII(-/-), FcRγ(-/-), and ST2(-/-) mice were sensitized and challenged with HDM, and inflammation was assessed based on results of flow cytometry and histology and cytokine production. Bone marrow-derived DCs from these strains were used in signaling and adoptive transfer experiments.', 'Our findings indicate that 2 distinct TH2 stimuli, ICs and HDM, use the FcRγ-associated receptors FcγRIII and Dectin-2, respectively, to promote TH2-mediated lung inflammation. In this study we demonstrate that both ICs and HDM induce expression of IL-33, a critical mediator in asthma pathogenesis and the differentiation of TH2 cells, in DCs. Upregulation of IL-33 in DCs is dependent on FcRγ, Toll-like receptor 4, and phosphoinositide 3-kinase. Exogenous IL-33 is sufficient to restore the development of TH2 responses in FcRγ-deficient mice. Finally, adoptive transfer of allergen-pulsed FcRγ(+/-) bone-marrow derived DCs restores the development of TH2-type inflammation in FcRγ-deficient mice, demonstrating the necessity of this signaling pathway in DCs for allergen-induced inflammation.
Example Output: 1

Example Input: It is very important for surgeons who perform minimally invasive surgery (MIS) to maintain proper postural stability, which kinematic research can determine. Previous studies in surgical ergonomics have shown that postural stability is correlated to instrument type, task difficulty, and skill level. What should also be considered is that surgeons may strategically change stance or joint movement to achieve better surgical outcomes while potentially subjecting themselves to greater risk. Background information about subjects, e.g., joint impairment, should be considered an important surgical ergonomic element. Such information can lead to more realistic and accurate conclusions about postural stability and joint kinematics.', 'A highly experienced and skilled right-handed surgeon developing carpal tunnel syndrome in both wrists was recruited into a small (6 subjects) performance study of pegboard transfer and circle-cutting tasks from the Fundamentals of Laparoscopic Surgery (FLS) skill set. Joint kinematics and postural data were collected using two associated force plates and a motion capture system of 12 digital, high-resolution, high-speed, infrared cameras.', 'Each task was completed in less than 90 s. In pegboard transfer, the subject increased shoulder abduction angle to align his hand and forearm and minimize wrist flexion. When circle-cutting required excessive wrist flexion, the subject maintained his lower body position and stance while twisting his torso, a strategy that appeared to stabilize tangential direction related to cutting while maintaining a fixed orientation of forearm, wrist, and hand. In another circle-cutting trial, the subject changed his stance primarily by shifting foot position as necessary to obtain better scissor approach angles. These compensatory, strategic movements caused an increase in overall postural sway but did not represent postural instability.
Example Output:
0