In this task you will be given a text passage from a trivia quiz. You should choose the category this question belongs to from these categories: History, Science, Social Science, Fine Arts, Literature. You can only choose one category, so if in doubt, please choose the closest match.
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Question: This man claimed that the doctrine of popular sovereignty could coexist with the Dred Scott decision during an explanation of his Freeport Doctrine. This man led a faction of a party whose other faction was led by John C. Breckenridge in the 1860 presidential election. Known as ""The Little Giant,"" this politician was instrumental getting the Kansas-Nebraska Act passed. For 10 points, name this Democratic Illinois Senator who engaged in a famous series of debates in 1858 with Abraham Lincoln.

Answer: History


Question: The Idler and The Rambler were two periodicals written by this man, and he popularized the term "Metaphysical Poets" in his series of biographies Lives of the Poets. The title prince travels with his mentor Imlac out of Happy Valley in search of true happiness in this author's prose work, Rasselas, while his greatest accomplishment was an epic of over 115,000 entries, the standard of its type until the creation of the Oxford English version. Author of an 18th-century Dictionary of the English Language, FTP name this British writer whose own biography was written by his one-time companion James Boswell.

Answer: Literature


Question: The 4-thio version of this molecule is useful as a zero-length crosslinker, and a fluorinated version of this molecule shows promise as an anticancer agent because it inhibits thymidylate synthase. The pseudo- version is found in the psi arm of certain structures, and its diphosphate is a carrier for glucose during glycogen synthesis. It spontaneously deaminates into cytosine, and its misincorporation is caused by extreme folate deficiency. First isolated by the hydrolysis of herring sperm, FTP, name this pyrimidine nucleotide that base pairs with adenine and replaces thymine in RNA.

Answer:
Science