Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Example Input: Notting hill is a small town west of London. Here lives shy William, a divorced man, who owns a little travel-book store. It was a Wednesday, when the poor shop keeper happened to meet Anna Scott ,a movie star who walked into his shop. They ran across each other in the street again. And they found themselves falling in love. But how could a poor man keep the love of a famous star? Their lives and their worlds were so different. Six months later, Anna was in London again for her new film. She came to William's thought ... Length :110 minutes Director:David Duning Cast:Julia Roberts(actress), Hugh Grant(actor)
Example Output: What is the passage mainly discussing ?

Example Input: The President of the European Parliament (Parliament's speaker) is Martin Schulz (S&D), elected in January 2012.
Example Output: Who led European Parliament?

Example Input: Nuclear receptor co-repressor (N-CoR) plays important role in transcriptional control mediated by several tumor suppressor proteins. Recently, we reported a role of misfolded-conformation dependent loss (MCDL) of N-CoR in the activation of oncogenic survival pathway in acute promyelocytic leukemia (APL). Since N-CoR plays important role in cellular homeostasis in various tissues, therefore, we hypothesized that an APL like MCDL of N-CoR might also be involved in other malignancy. Indeed, our initial screening of N-CoR status in various leukemia and solid tumor cells revealed an APL like MCDL of N-CoR in primary and secondary tumor cells derived from non-small cell lung cancer (NSCLC). The NSCLC cell specific N-CoR loss could be blocked by Kaletra, a clinical grade protease inhibitor and by genistein, an inhibitor of N-CoR misfolding previously characterized by us. The misfolded N-CoR presented in NSCLC cells was linked to the amplification of ER stress and was subjected to degradation by NSCLC cell specific aberrant protease activity. In NSCLC cells, misfolded N-CoR was found to be associated with Hsc70, a molecular chaperone involved in chaperone mediated autophagy (CMA). Genetic and chemical inhibition of Lamp2A, a rate limiting factor of CMA, significantly blocked the loss of N-CoR in NSCLC cells, suggesting a crucial role of CMA in N-CoR degradation. These findings identify an important role of CMA-induced degradation of misfolded N-CoR in the neutralization of ER stress and suggest a possible role of misfolded N-CoR protein in the activation of oncogenic survival pathway in NSCLC cells.
Example Output:
Which is the receptor for substrates of Chaperone Mediated Autophagy?