In this task, you are given a sentence in the Spanish language. Your task is to translate the Spanish sentence into the English language.

[Q]: La presencia de un trastorno mental y el uso patológico de sustancias tóxicas
[A]: The presence of a mental disorder and the pathological use of toxic substances


[Q]: La ruta de los fosfatos de pentosa produce
[A]: The pentose phosphate pathway produces


[Q]: ¿Cuál de los siguientes contextos clínicos debe hacernos sospechar un proceso paraneoplásico y, por tanto, nos obliga a realizar un despistaje de neoplasia maligna?
[A]:
Which of the following clinical contexts should make us suspect a paraneoplastic process and, therefore, obliges us to perform a screening for malignancy?