Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Input: Consider Input: Question: Does single copy of variant CYP2A6 alleles confer susceptibility to liver dysfunction in patients treated with coumarin?
Answer: No evidence was obtained that the studied polymorphism in CYP2A6 is a determinant of the coumarin-associated liver dysfunction.

Output: no


Input: Consider Input: Question: Is cytoglobin upregulated by tumour hypoxia and silenced by promoter hypermethylation in head and neck cancer?
Answer: We conclude that the CYGB gene is regulated by both promoter methylation and tumour hypoxia in HNSCC and that increased expression of this gene correlates with clincopathological measures of a tumour's biological aggression.

Output: yes


Input: Consider Input: Question: Is codeine and clinical impairment in samples in which morphine detected?
Answer: Codeine appeared to have some dose-dependent effect on the central nervous system that may lead to impairment as judged from a CTD, independent of measurable blood morphine concentrations. This supports the view that some codeine effects do not seem to be mediated by morphine.


Output: no