instruction:
Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
question:
The increasing prevalence of methamphetamine abuse and the severity of the associated ulcers should alert ophthalmologists to the problem of methamphetamine-related keratitis.
answer:
adverse drug event


question:
Depressive symptoms disappeared after interferon therapy was stopped.
answer:
adverse drug event


question:
Cessation of MTX therapy led to complete regression of the tumor.
answer:

non-adverse drug event