Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

In 1997 the Kymi Province was merged with the Uusimaa Province and the southern parts of the Hame Province into the new Southern Finland Province.
What was replaced Kymi Province?

It had been some time since Jack had seen the old man.Over the phone ,his mother told him,"Mr.Belser died last night ,The funeral is Wednesday."Memories flashed through his mind like an old newsreel as he sat quietly remembering his childhood days. When Jack was very young ,his father died.Mr Belser,who lived in the same neighborhood with them,spent as much time as he could to make sure Jack had a man's influence in his life.He spent a lot of time teachimg Jack he thought what was important in his following life.If Mr.Belser hadn' taught him how to weave,he wouldn't be in this business now.So he promised his mother he would attend Mr.Belser's funeral. "You'd better not drive your car.It's a long way."his mother warned him. Busy as he was,he kept his word.Though tired from the earliest flight,Jack tried his best to help.Mr.Belser's funeral was small because he had no children of his own and most of his s had passed away. The night before he had to return home,Jack and his mother stopped by to see the old house Mr.Belser once lived.Now it belonged to him.He bought the house from one of his s. The house was exactly as he remembered.Every step held memories.Every picture,every piece of furniture... Jadk stopped suddenly. The box on his desk was gone!He once asked the old man what was inside.He just smiled and said it was the most valuable thing to him,though it almost cost nothing to others.He figured that someone from the Belser family had taken it ."I will never know what was so valuable to him."Jack thought disappotntedly. Three days later returning home from work,Jack discovered a small package in his mailbox. The handwriting was difficult to read,but the return address caught his attention."Mr.Harold Belser"it read. Jack couldn't wait to open it .Inside lay the familiar small box.His heart racing,Jack unlocked the box.Inside he found a gold pocket watch with these words engraved:"Jack,Thanks for your time!Harold Belser." "The thing he valued most was my time."Jack held the watch before his chest,tears filling his eyes.
What did Mr.Belser teach Jack when he aws young?

-Synuclein is the major pathological component of synucleinopathies including Parkinson's disease and dementia with Lewy bodies. Recent studies have demonstrated that -synuclein also plays important roles in the release of synaptic vesicles and synaptic membrane recycling in healthy neurons. However, the precise relationship between the pathogenicity and physiological functions of -synuclein remains to be elucidated. To address this issue, we investigated the subcellular localization of -synuclein in normal and pathological conditions using primary mouse hippocampal neuronal cultures. While some neurons expressed high levels of -synuclein in presynaptic boutons and cell bodies, other neurons either did not or only very weakly expressed the protein. These -synuclein-negative cells were identified as inhibitory neurons by immunostaining with specific antibodies against glutamic acid decarboxylase (GAD), parvalbumin, and somatostatin. In contrast, -synuclein-positive synapses were colocalized with the excitatory synapse marker vesicular glutamate transporter-1. This expression profile of -synuclein was conserved in the hippocampus in vivo. In addition, we found that while presynaptic -synuclein colocalizes with synapsin, a marker of presynaptic vesicles, it is not essential for activity-dependent membrane recycling induced by high potassium treatment. Exogenous supply of preformed fibrils generated by recombinant -synuclein was shown to promote the formation of Lewy body (LB) -like intracellular aggregates involving endogenous -synuclein. GAD-positive neurons did not form LB-like aggregates following treatment with preformed fibrils, however, exogenous expression of human -synuclein allowed intracellular aggregate formation in these cells. These results suggest the presence of a different mechanism for regulation of the expression of -synuclein between excitatory and inhibitory neurons. Furthermore, -synuclein expression levels may determine the efficiency of intracellular aggregate formation in different neuronal subtypes.

Which is the primary protein component of Lewy bodies?