Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does toll-like receptor 4 signaling contribute to Paclitaxel-induced peripheral neuropathy?
Answer: The toll-like receptor TLR4 and MyD88 signaling pathway could be a new potential therapeutic target in paclitaxel-induced painful neuropathy.
yes

Question: Does carriage of the methylenetetrahydrofolate reductase ( MTHFR ) C677T polymorphism influence the first and second trimester uterine artery Doppler flow?
Answer: In summary, the data presented in this adequately powered, prospective, controlled study establish that the MTHFR C677T polymorphism does not influence Doppler flow measurements.
no

Question: Does disruption of Physiological Balance Between Nitric Oxide and Endothelium-Dependent Hyperpolarization impair Cardiovascular Homeostasis in Mice?
Answer: These results indicate that excessive endothelium-derived NO with reduced EDH impairs cardiovascular homeostasis in mice in vivo.

yes