Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Ex Input:
Ashley and Chris work in the same department designing postcards. Chris had a college degree in art and deeply felt that the degree of his designs was excellent. His last postcard showed the depth of a desert's beauty and delights. "It's just a picture of the desert," Ashley said. "Not deep at all." "Some people desire seeing beauty," Chris replied. "Mine delivers that". Ashley laughed and said, "well, that depends on what you think beauty is." Days later, someone delivered a letter to Ashley. The letter said, "You are worthy of the bad things that will come your way. You will know the taste of defeat, and I will destroy you." Ashley suddenly felt very cold. It was as if the room temperature had dropped 30 degrees. "Who would do such a shocking deed?" she wondered. "I will not let a simple letter defeat me." Just then, Chris came into the room and offered Ashley a piece of his sandwich. "Try some," he smiled widely. "It's delicious." "Are you trying to poison me?" Ashley asked. Chris's answer was delayed from confusion. "What's your problem?" he asked. The next day, Ashley brought a bat to use to defend herself. When Chris saw her bat, he joked, "Defend and win one for the team." Ashley took no notice of him. She spent the whole day reading self-defending books and placed her work on delay. "You can't delay your work. Our job demands us to do our work on time," Chris said. "We must meet the demands of our job." "You're not the boss," Ashley replied. "Don't make demands of me." Because Ashley failed to do her work, she was fired. Chris glanced at Ashley's empty desk and smiled.

Ex Output:
What kind of work did Chris and Ashley do?


Ex Input:
You have been badly injured in a car accident. It is necessary to give you a blood transfusion because you lost a great deal of blood in the accident. However, special care must be taken in selecting new blood for you. If the blood is too different from your own, the transfusion could kill you. There are four basic types of blood; A, B, AB, and O. A simple test can make sure of a person's blood type. Everybody is born with one of these four types of blood. Blood type, like hair color1 and height, is received from parents. The four groups must be transfused carefully. A and B cannot be mixed. A and B cannot receive AB, but AB may receive A or B. O can give to any other group; therefore, it is often called the universal donor . For the opposite reason, AB is sometimes called the universal recipient . However, because so many reactions can happen in transfusions , patients usually receive only salt of plasma (liquid part of blood) until their blood can be matched as exactly as possible in the blood bank of a hospital. In this way, it is possible to prevent the transfusion from any bad reactions.

Ex Output:
People with type A blood can receive type     .


Ex Input:
Epidermal growth factor receptor (EGFR) gene mutations have been found in a subset of non-small cell lung cancer (NSCLC) with good clinical response to gefitinib therapy. A quick and sensitive method with large throughput is required to utilize the information to determine whether the molecular targeted therapy should be applied for the particular NSCLC patients. Using probes for the 13 different mutations including 11 that have already been reported, we have genotyped the EGFR mutation status in 94 NSCLC patients using the TaqMan PCR assay. We have also genotyped the EGFR mutations status in additional 182 NSCLC patients, as well as 63 gastric, 95 esophagus and 70 colon carcinoma patients. In 94 NSCLC samples, the result of the TaqMan PCR assay perfectly matched with that of the sequencing excluding one patient. In one sample in which no EGFR mutation was detected by direct sequencing, the TaqMan PCR assay detected a mutation. This patient was a gefitinib responder. In a serial dilution study, the assay could detect a mutant sample diluted in 1/10 with a wild-type sample. Of 182 NSCLC samples, 46 mutations were detected. EGFR mutation was significantly correlated with gender, smoking status, pathological subtypes, and differentiation of lung cancers. There was no mutation detected by the TaqMan PCR assay in gastric, esophagus and colon carcinomas. TaqMan PCR assay is a rapid and sensitive method of detection of EGFR mutations with high throughput, and may be useful to determine whether gefitinib should be offered for the treatment of NSCLC patients. The TaqMan PCR assay can offer us a complementary and confirmative test.

Ex Output:

Mutations in which gene determine response to both erlotinib and gefitinib?