TASK DEFINITION: In this task, you are given a part of an article. Your task is to generate headline (title) for this text. Preferred headlines are under fifteen words.
PROBLEM: Protein subcellular localization prediction is an important and challenging problem. The traditional biology experiments are expensive and time-consuming, so more and more research interests tend to a series of machine learning approaches for predicting protein subcellular location. There are two main difficult problems among the existing state-of-the-art methods. First, most of the existing techniques are designed to deal with the multi-class but not the multi-label classification, which ignores the connection between the multiple labels. In reality, multiple location proteins implicate that there are vital and unique biological significances worthy of special focus, which cannot be ignored. Second, the techniques for handling imbalanced data in multi-label classification problem is significant but less. For solving the two issues, we have developed an ensemble multi-label classifier called HPSLPred which can be applied for the multi-label classification with imbalanced protein source. For the conveniences of users, a user-friendly webserver for HPSLPred was established at http://server.malab.cn/HPSLPred.

SOLUTION: HPSLPred: An Ensemble Multi-label Classifier for Human Protein Subcellular Location Prediction with Imbalanced Source

PROBLEM: The holy Quran is the holy book of the Muslims. It contains information about many domains. Often people search for particular concepts of holy Quran based on the relations among concepts. An ontological modeling of holy Quran can be useful in such a scenario. In this paper, we have modeled nature related concepts of holy Quran using OWL (Web Ontology Language) / RDF (Resource Description Framework). Our methodology involves identifying nature related concepts mentioned in holy Quran and identifying relations among those concepts. These concepts and relations are represented as classes/instances and properties of an OWL ontology. Later, in the result section it is shown that, using the Ontological model, SPARQL queries can retrieve verses and concepts of interest. Thus, this modeling helps semantic search and query on the holy Quran. In this work, we have used English translation of the holy Quran by Sahih International, Protege OWL Editor and for querying we have used SPARQL. Keywords— Quranic Ontology; Semantic Quran; Quranic Knowledge Representation.

SOLUTION: Applying Ontological Modeling on Quranic “Nature” Domain

PROBLEM: A major task in systematic reviews is abstract screening, i.e., excluding, often hundreds or thousand of, irrelevant citations returned from a database search based on titles and abstracts. Thus, a systematic review platform that can automate the abstract screening process is of huge importance. Several methods have been proposed for this task. However, it is very hard to clearly understand the applicability of these methods in a systematic review platform because of the following challenges: (1) the use of non-overlapping metrics for the evaluation of the proposed methods, (2) usage of features that are very hard to collect, (3) using a small set of reviews for the evaluation, and (4) no solid statistical testing or equivalence grouping of the methods. In this paper, we use feature representation that can be extracted per citation. We evaluate SVM based methods (commonly used) on a large set of reviews (61) and metrics (11) to provide equivalence grouping of methods based on a solid statistical test. Our analysis also includes a strong variability of the metrics using 500x2 cross validation. While some methods shine for different metrics and for different datasets, there is no single method that dominates the pack. Furthermore, we observe that in some cases relevant (included) citations can be found after screening only 15-20% of them via a certainty based sampling. A few included citations present outlying characteristics and can only be found after a very large number of screening steps. Finally, we present an ensemble algorithm for producing a 5star rating of citations based on their relevance. Such algorithm combines the best methods from our evaluation and through its 5-star rating outputs a more easy-to-consume prediction.

SOLUTION:
A large scale study of SVM based methods for abstract screening in systematic reviews*