In this task, you will be given a sentence. You need to reconize the name of the disorder or disease. Disease is a disorder of structure or function in a human, animal, or plant, especially one that produces specific symptoms or that affects a specific location and is not simply a direct result of physical injury. Although there might be several correct answers, you need to write one of them.

Input: Consider Input:  Liver biopsy is also used to establish the presence or absence of cirrhosis , which can affect prognosis and management .

Output: cirrhosis


Input: Consider Input:  Aggregation of mutant Smad4 ES cells with wild - type tetraploid morulae rescues the gastrulation defect .

Output: gastrulation defect


Input: Consider Input:  The cyclin - dependent kinase inhibitor , p27 , accumulates upon serum withdrawal , only in the presence of VHL , as a result of the stabilization of the protein .


Output: VHL