In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.

[Q]:  Previously described enhancement of in vitro transcription that was only seen with nuclear extracts derived from B - cell neoplasms corresponding to the late stages of B - cell differentiation was shown to be dependent on the actions of these factor ( s ) on the DNA region within the V kappa gene promoter .
[A]: V kappa


[Q]:  The results suggest that M . tuberculosis can upregulate HIV - 1 expression in T cells and could thus have the potential to influence the pathogenesis of HIV - 1 infection .
[A]: HIV - 1


[Q]:  Reversal of this functional uncoupling may be required before Jak3 / Stat5 inhibitors will be useful in the treatment of this malignancy .
[A]:
Jak3 / Stat5