In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Input: Consider Input: Paragraph: Delineation of the intricacies of protein function from macromolecular structure constitutes a continual obstacle in the study of cell and pathogen biology. Structure-based phylogenetic analysis has emerged as a powerful tool for addressing this challenge, allowing the detection and quantification of conserved architectural properties between proteins, including those with low or no detectable sequence homology. With a focus on viral protein structure, we highlight how a number of investigations have utilized this powerful method to infer common functionality and ancestry. 
 Title: Unraveling virus relationships by structure-based phylogenetic classification

Output: True


Input: Consider Input: Paragraph: This article investigates an epidemic spreading among several locations through a transportation system, with a hub connecting these locations. Public transportation is not only a bridge through which infections travel from one location to another but also a place where infections occur since individuals are typically in close proximity to each other due to the limited space in these systems. A mathematical model is constructed to study the spread of an infectious disease through such systems. A variant of the next generation method is proposed and used to provide upper and lower bounds of the basic reproduction number for the model. Our investigation indicates that increasing transportation efficiency, and improving sanitation and ventilation of the public transportation system decrease the chance of an outbreak occurring. Moreover, discouraging unnecessary travel during an epidemic also decreases the chance of an outbreak. However, reducing travel by infectives while allowing susceptibles to travel may not be enough to avoid an outbreak. 
 Title: Spatial spread of an epidemic through public transportation systems with a hub

Output: True


Input: Consider Input: Paragraph: 2 3 Halim Maaroufi 4 Institut de biologie intégrative et des systèmes (IBIS). Université Laval. Quebec. Canada 5 Halim.maaroufi@ibis.ulaval.ca 6 7 ABSTRACT The novel betacoronavirus (SARS-CoV-2) is highly contagious and can cause 8 serious acute respiratory illness syndromes, often fatal, called covid-19. It is an urgent priority to 9 better understand SARS-CoV-2 infection mechanisms that will help in the development of 10 prophylactic vaccines and therapeutics that are very important to people health and socioeconomic 11 stability around the world. The surface coronavirus spike (S) glycoprotein is considered as a key 12 factor in host specificity because it mediates infection by receptor-recognition and membrane 13 fusion. Here the analysis of CoV-2 S protein revealed in S1subunit a B56-binding LxxIxE-like 14 motif that could recruit the host protein phosphatase 2A (PP2A). This motif is absent in SARS-15 CoV and MERS-CoV. PP2A is a major family of serine/threonine phosphatases in eukaryotic cells. 16 Phosphatases and kinases are big players in the regulation of pro-inflammatory responses during 17 pathogenic infections. Moreover, studies have shown that viruses use multiple strategies to target 18 PP2A in order to manipulate host's antiviral responses. The latest studies have indicated that 19 SARS-CoV-2 is involved in sustained inflammation in the host. Therefore, by controlling acute 20 inflammation; it is possible to eliminate its dangerous effects on the host. Among efforts to fight 21 covid-19, the interaction between LxxIxE-like motif and PP2A-B56-binding pocket could be a 22 target for the development of a bioactive peptide and ligand inhibitors for therapeutic purposes. 23 24 25 
 Title: The Spike Protein S1 Subunit of SARS-CoV-2 Contains an LxxIxE-like Motif that is Known to Recruit the Host PP2A-B56 Phosphatase


Output: False