TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Does the presence of high-grade prostatic intraepithelial neoplasia or atypia on prostate biopsy adversely affect prostatectomy outcomes for patients otherwise eligible for active surveillance?
Answer: The presence of HGPIN or ASAP does not increase the risk of upgrading, upstaging, or adverse pathology at the time of prostatectomy for patients who meet the AS criteria. If otherwise suitable, HGPIN and ASAP should not impact the decision to choose AS. However, analysis of prospective AS trials is required to determine if HGPIN or ASAP impacts tumor progression once on AS.

SOLUTION: no

PROBLEM: Question: Do novel meta-analysis-derived type 2 diabetes risk loci determine prediabetic phenotypes?
Answer: In contrast to the first series of GWA-derived type 2 diabetes candidate SNPs, we could not detect reliable associations of the novel risk loci with prediabetic phenotypes. Possible weak effects of ADAMTS9 SNP rs4607103 and VEGFA SNP rs9472138 on insulin sensitivity and insulin secretion, respectively, await further confirmation by larger studies.

SOLUTION: no

PROBLEM: Question: Does ibulocydine sensitize human cancers to radiotherapy by induction of mitochondria-mediated apoptosis?
Answer: IB demonstrated the property of sensitizing human cancer cells to RT by induction of mitochondria-mediated apoptosis, suggesting that IB deserves to be applied for chemoradiotherapy.

SOLUTION:
yes