In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: Indinavir is a selective inhibitor of HIV protease because: 
 Options:  <1> By hydrolysis, the active drug is generated. <2> Rents irreversibly the active center of the enzyme. <3> Its structure mimics the transition state of the reaction catalyzed by the enzyme. <4> It is a suicide inhibitor. <5> Its symmetric structure interacts effectively with the active center of the enzyme.
3

Question: To detect the occurrence of prerenal acute renal failure in a patient, the nurse should monitor the presence of: 
 Options:  <1> Signs of low cardiac output. <2> Hematuria <3> Urine cloudy and smelly. <4> Colic pain <5> Elevation of creatinine clearance.
1

Question: What type of economic evaluation analysis in health compares the costs of the results of different health interventions measured in years of life adjusted for quality (QALY)? 
 Options:  <1> Analysis of minimization of costs. <2> Cost effectiveness analysis. <3> Cost utility analysis. <4> Cost benefit analysis. <5> Analysis of the cost of health.

3