Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.
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Question: The story makes it clear that cost of the test is currently speculative (“could cost about $500”) and goes even further to caution that: “Johns Hopkins holds the patent and has not licensed it as yet to a company that would ultimately set the price.” The story makes the two key results of the test quite clear. First, that the 1,005 people tested already had been diagnosed with one of eight common cancers, and the blood test was able to detect cancer in about 70 percent of them. Second, the test was also given to 812 people without cancer and only a false reading for cancer less than 1 percent of the time. Including the additional finding that the test was only able to detect cancer in about 40 percent of the patients with early cancer (ie. stage I) was a thoughtful way of introducing the relevant issue of falsely negative tests. The story does an excellent job of finding an independent source who explains that one of the potential risks of cancer screening tests is either identifying cancers that are not there, or are benign, and can lead to “pointless and potentially dangerous treatments.” The opposite harm is also mentioned; that is, a screening test that erroneously gives a negative result, leading providers to falsely reassure a patient that cancer is not there. Cautious language is used at many points in the story and it does three things quite well. First, it lists the most important limitation of the study: The screening test studied was unable to identify the type of cancer. Second, the implications of both falsely positive and falsely negative tests were explained succinctly and placed in a clinical context that would matter to those undergoing screening. Finally, we were very encouraged by the inclusion of this sentence: “… the researchers will still have to demonstrate that the test improves and extends the lives of cancer patients.” There is no disease mongering in this story. The two independent sources cited provide important context for understanding the strengths, limitations, and clinical context of the screening test. This was a tough call, but ultimately we felt the story would have been stronger had it mentioned the performance of current screening methods for some of the cancer types, such as Cologuard for colon cancer. That said, we were glad the story included some of the pitfalls of screening for prostate and breast cancer, as well as the long struggle to develop more blood tests for cancer. It’s mentioned the authors of the study are “hoping their idea would eventually lead to a $500 test … but they have a long way to go.” Future studies of the screening test are also discussed, so it seems clear this test is not currently available. It’s made clear that “there have been many attempts over the decades to develop blood tests to screen for cancers … but these methods don’t give reliable results.” It’s also pointed out that what makes this screening test unique is that it combines two previously used methods (screening for proteins and for DNA) into one test. This story does not appear to rely upon a news release.

Answer: Scientists Edge Closer To A Blood Test To Detect Cancers


Question: Most people know roughly what a bottle of vitamin D supplements might cost them, so the lack of information on cost is not a significant gap. We appreciate that the story provided data showing the large and growing amount our society is spending on vitamin D supplements ($430 million in 2009), with apparently little health benefit to show for it. The story was mostly concerned with discussing the lack of benefit from taking extra vitamin D and calcium. And in this area it excels. While the story does lack precision when it suggests that adolescent girls should be getting more calcium (it never specifies how much they are getting now, how much more they’d need to meet the recommendations, or what benefits they might expect from this increased intake), it would be difficult for a journalist to come up with any sort of quantifiable benefit or harm estimate from the IOM report. The story captured the overall gist of the problem, which is that the evidence base is complex and still inadequate. The story notes that, contrary to the claims of many advocates for increased supplemental vitamin D, there is evidence that high levels of vitamin D may have adverse effects, such as increased risk for fractures and an increase in the overall death rate. The story also explained that too much calcium has been linked to increased risk of kidney stones and, more tentatively, heart disease. The story did a good job of describing how the expert committee conducted its review and what evidence they found. Importantly, it noted that  claims of benefit from extra vitamin D are based on observational studies that most scientists agree “cannot determine cause and effect.” We also like that the story solicited opinions from a variety of experts with no obvious stake in the controversy. This produced a number of quotes that emphasized the need for restraint when interpreting the research on vitamin D. Examples: “I think this report will make people more cautious” and “The onus is on the people who propose extra calcium and vitamin D to show it is safe before they push it on people.” Although we agree with the story’s skeptical overall message, we think it may have slammed the door just a bit too hard on the possibility of benefit from supplemental vitamin D. While claims of benefit may not be supported by the currently available evidence, they have not been conclusively disproved in randomized controlled studies, either. In fact, research is now underway to determine whether the benefits found in observational studies of vitamin D can be replicated in more rigorously designed trials. The story probably should have mentioned this research, and left the door to potential benefits open just a crack. No disease-mongering here. The diversity of independent voices included in this story is a real strength. Although it solicits the obligatory comment from a supplement industry spokesman, it didn’t go out of its way to find any of the more widely known vitamin D experts, some of whom have been issuing recommendations that are untenable based on current evidence. The enthusiasm of some of these researchers might be explained by their significant career and financial interests in promoting vitamin D. Not applicable for this story. The approaches discussed are not new, and there’s not really any alternative to getting adequate amounts of these essential nutrients. The availability of vitamin D from diet, sunlight and supplements is clear from the story. The novelty of vitamin D and calcium is not really in question, so we’ll call this not applicable. This story was not based on a news release.

Answer: Report Questions Need for 2 Diet Supplements


Question: “We still have a big problem at hand,” Samoa’s Director General of Health Leausa Take Naseri said in a video statement. He said more than 140 new cases of people contracting the virus had been recorded within the past day, bringing the total to about 2,200 cases since the outbreak began last month. He said there are about 20 critically ill children who remain in hospital intensive care units. Samoa declared a state of emergency nine days ago, closing all its schools, banning children from public gatherings and mandating that everybody get vaccinated. Teams of people have been traveling the country administering thousands of vaccines. The government also shut down a private clinic and is investigating how hundreds of vaccines were taken without authorization and then sold for a fee. The median age of those who have died is 13 months, according to government figures. The deaths include 24 children under the age of 5, 11 of whom were infants under 12 months. The other person who died was in their 30s. In all, 679 people have been admitted to Samoan hospitals with the disease, accounting for two-thirds of all recent hospital admissions. A majority have been discharged, with about 183 remaining in hospitals. “These hospitals are not designed to deal with this,” Dr. Scott Wilson told Newshub in the capital, Apia. “The minute you get hospitals running at 200 to 300 percent capacity — I think it speaks for itself. It’s incredibly serious.” Figures from the World Health Organization and UNICEF indicate that measles immunization rates among Samoan infants have fallen steeply from over 70% in 2013 to under 30% last year. Helen Petousis-Harris, a vaccine expert at New Zealand’s University of Auckland, said the Samoan government halted its immunization program for several months last year after two infants died from a medical mishap involving a vaccine. Tonga, Fiji and New Zealand have also reported outbreaks of measles but on a smaller scale than in Samoa. American Samoa, which has declared a public health emergency, is requiring that travelers from Samoa and Tonga prove they have been vaccinated or are immune from measles before being allowed into the U.S. territory.

Answer:
Samoa measles epidemic worsens with 24 children now dead.