In this task, you're given a paragraph from the research paper and your task is to generate a suitable title for the research paper based on the given paper. Under 100 words is a good title length.

[EX Q]: Background: A novel strain of influenza A (H1N1) was identified in April 2009 and developed into a pandemic by June 2009. This rapid and unexpected event had enormous implications for infection preventionists (IP) internationally. Lessons learned from this event should guide future pandemic planning efforts. Methods: Focus groups were conducted at the Association for Professionals in Infection Control and Epidemiology, Inc, (APIC) 2009 conference to evaluate IPs' experience with the novel H1N1 influenza pandemic and assess their perceived needs related to novel H1N1 topics and products required for future education and reference materials. Results: Forty IPs (37 from the United States and 3 international) participated in the focus groups. Needed reference materials identified by attendees included infection prevention guidance for nonacute care settings; occupational health polices; and brief, multilanguage patient/family educational materials. Educational topics on which IPs need to be trained include isolation precautions/ personal protective equipment recommendations for novel H1N1 patients, coordination between hospitals and community response agencies, and surge management. The rapidly changing and conflicting recommendations related to patient management made responding to this event challenging. IPs require synthesized infection prevention guidelines developed in a concise, real-time format. Conclusion: IPs must continue to partner with public health and other response agencies to address gaps in pandemic planning.
[EX A]: Infection preventionists' experience during the first months of the 2009 novel H1N1 influenza A pandemic

[EX Q]: Redirecting the splicing machinery through the hybridization of high affinity, RNase H-incompetent oligonucleotide analogs such as phosphoramidate morpholino oligonucleotides (PMO) might lead to important clinical applications. Chemical conjugation of PMO to arginine-rich cell penetrating peptides (CPP) such as (R-Ahx-R) 4 (with Ahx standing for 6-aminohexanoic acid) leads to sequencespecific splicing correction in the absence of endosomolytic agents in cell culture at variance with most conventional CPPs. Importantly, (R-Ahx-R) 4 -PMO conjugates are effective in mouse models of various viral infections and Duchenne muscular dystrophy. Unfortunately, active doses in some applications might be close to cytotoxic ones thus presenting challenge for systemic administration of the conjugates in those clinical settings. Structureactivity relationship studies have thus been undertaken to unravel CPP structural features important for the efficient nuclear delivery of the conjugated PMO and limiting steps in their internalization pathway. Affinity for heparin (taken as a model heparan sulfate), hydrophobicity, cellular uptake, intracellular distribution and splicing correction have been monitored. Spacing between the charges, hydrophobicity of the linker between the Arg-groups and Arg-stereochemistry influence splicing correction efficiency. A significant correlation between splicing correction efficiency, affinity for heparin and ability to destabilize model synthetic vesicles has been observed but no correlation with cellular uptake has been found. Efforts will have to focus on endosomal escape since it appears to remain the limiting factor for the delivery of these splice-redirecting ON analogs.
[EX A]: Delivery of steric block morpholino oligomers by (R-X-R) 4 peptides: structure-activity studies

[EX Q]: Acute respiratory failure is a common reason for admission to the pediatric intensive care unit in oncology patients [1] . Acute respiratory complications are also common after pediatric hematopoietic stem cell transplant (HSCT), accounting for a high proportion of HSCT-related morbidity and mortality [2] [3] [4] . When pulmonary disease in HSCT patients progresses to acute respiratory failure, they often require emergent intubation and support with invasive mechanical ventilation (IMV) [3, 5]; many children develop refractory hypoxemia and multi-organ failure. Tamburro et al. reported outcomes in a cohort of mechanically ventilated pediatric oncology and HSCT patients. The non-HSCT patients had better outcomes than the HSCT patients with 6-month survival at 60% [6] . While the outcomes are better in the oncology patients, they are nevertheless worse than immunocompetent patients. Their immunocompromised status and chemotherapy-related multi-organ failure are likely complicating factors affecting outcomes in this cohort. Focusing on the more complicated HSCT patients, intubation for HSCT-related acute lung injury (ALI) often led to early redirection of care due to high fatality two decades ago; recent reports show that outcomes have improved with improved
[EX A]:
Acute Respiratory Failure and Management Acute Respiratory Failure