Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: METHOD: Case analysis of a poly-drug overdose (venlafaxine, topiramate, divalproex sodium, risperidone, and carbamazepine) presenting with mixed SS/NMS features and whose clinical management suggests a practical algorithm for treatment of undifferentiated SS/NMS in critical care settings.

Output: adverse drug event


Input: Consider Input: CASE SUMMARY: A 66-year-old man with a background history of breast carcinoma was admitted with pleuritic chest pain.

Output: non-adverse drug event


Input: Consider Input: This fourth type of cutaneous minocycline hyperpigmentation may be a variant of Type I, but based on clinical, pathological and microanalytical differences, appears to be a new entity.


Output: adverse drug event