In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Example Input: Question: ADH increases the osmolality of the renal interstitial medium because it increases: 
 Options:  <1> The permeability to urea in the collector tube. <2> The water permeability of the ascending loop of Henle. <3> The flow in the straight vessels. <4> The reabsorption of NaCl in the collecting tubule. <5> The renal excretion of water.
Example Output: 1

Example Input: Question: The tissue is avascular: 
 Options:  <1> Epithelial. <2> Conjunctive. <3> Osseous. <4> Muscular. <5> Nervous.
Example Output: 1

Example Input: Question: In the alcaptonuria the defective enzyme can be: 
 Options:  <1> Dihydrobiopterin reductase. <2> Tyrosine aminotransferase. <3> p-hydroxyphenylpyruvate dioxygenase. <4> Homogentisic 1,2-dioxygenase. <5> Fumarilacetoacetasa.
Example Output:
4