Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Q: Question: Does variation in the gene for human peroxisome proliferator activated receptor gamma ( PPARgamma ) play a major role in the development of morbid obesity?
Answer: Variation in the PPARgamma gene is unlikely to play a major role in the development of morbid obesity.

A: no
****
Q: Question: Does specific angiotensin II receptor blockage improve intestinal perfusion during graded hypovolemia in pigs?
Answer: Specific AT1 blockade before acute hypovolemia significantly ameliorated mesenteric and, in particular, jejunal mucosal hypoperfusion. In addition, cardiovascular stability was improved, and mortality in conjunction with acute hypovolemia and retransfusion could be completely avoided. These findings support a fundamental role of the renin-angiotensin system in the mesenteric response to acute hypovolemia and indicate a substantial interventional potential for candesartan in conjunction with circulatory stress.

A: yes
****
Q: Question: Is cross-section perimeter a suitable parameter to describe the effects of different baffle geometries in shaken microtiter plates?
Answer: Calculated and experimentally determined OTRmax values agree within ± 30% accuracy. Furthermore, undesired out-of-phase operating conditions can be identified by using the relative perimeter as key parameter. Finally, an optimum well geometry characterized by an increased perimeter of 10% compared to the unbaffled round geometry is identified. This study may also assist to comprehensively describe and optimize the baffles of shake flasks in future.

A:
yes
****