Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

[EX Q]: Question: Is the G-308A variant of the Tumor Necrosis Factor-alpha ( TNF-alpha ) gene associated with obesity , insulin resistance and body fat distribution?
Answer: Our study did not detect any significant association of the G-308A TNFalpha polymorphism with obesity or with its clinical and metabolic abnormalities in this population. Our data suggests that, in our population, the G-308A TNFalpha polymorphism is unlikely to play a major role in the pathogenesis of these conditions.
[EX A]: no

[EX Q]: Question: Is cytosine deamination a major cause of baseline noise in next-generation sequencing?
Answer: Baseline noise during NGS is mostly due to cytosine deamination, the source of which is likely to be both biologic and an artifact of thermocycling, and it can be reduced by UNG pretreatment.
[EX A]: yes

[EX Q]: Question: Do a phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer?
Answer: Treatment with 200 μmoles/day of sulforaphane-rich extracts did not lead to ≥50% PSA declines in the majority of patients. However, because of the safety of treatment and the effects on PSADT modulation, further studies, including those with higher doses, may be warranted to clarify the role of sulforaphane as a prevention agent or treatment agent.
[EX A]:
yes