instruction:
Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
question:
Context: Common cellular and molecular mechanisms including protein aggregation and inclusion body formation are involved in many neurodegenerative diseases. -Synuclein is a major component of Lewy bodies in Parkinson's disease (PD) as well as in glial cytoplasmic inclusions in multiple system atrophy (MSA). Tau is a principal component of neurofibrillary and glial tangles in tauopathies. Recently, TDP-43 was identified as a component of ubiquitinated inclusions in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. PD is traditionally considered a movement disorder with hallmark lesions in the brainstem pigmented nuclei. However, pathological changes occur in widespread regions of the central and peripheral nervous systems in this disease. Furthermore, primary glial involvement ("gliodegeneration") can be observed in PD and MSA as well as in tauopathy. The present article reviews abnormal protein accumulation and inclusion body formation inside and outside the central nervous system. 
 Question: Which is the primary protein component of Lewy bodies?
answer:
αsyn


question:
Context: David T. Friendly (born May 1, 1956) is an American film producer best known for co-producing the 2006 film Little Miss Sunshine, for which he was nominated for an Academy Award for Best Picture. 
 Question: What award was David T. Friendly nominated for?
answer:
academy award for best picture


question:
Context: In a New York City residence, Pierre Delacroix (Damon Wayans) rises to begin his daily routine. Brushing his teeth, he gives us by voice over a definition of satire. He tells us that with the rise of the Internet, video and interactive games, his field as a television writer has seen a drop in popularity. Meanwhile, in a dilapidated building, squatter Womack (Tommy Davidson) wakes up his friend Manray (Savion Glover) for a day of work. This consists of travelling to the CNS (Continental Network System) building where Delacroix works, and Manray tap dancing to entertain the workers. They then collect money from the workers. The men see Delacroix walk by, and ask him for monetary help in the form of work of some kind.Delacroix walks into a staff meeting late and is immediately castigated by his boss, Thomas Dunwitty (Michael Rapaport). Dunwitty informs the staff that CNS has poor ratings. He says he wants them to write funnier material, and ends the meeting. In the privacy of his office, Dunwitty tells Delacroix that the material Delacroix's been writing for him seems like it's about white people with black faces. Dunwitty asserts that Delacroix is an "oreo" with his Harvard education, because he won't write a "n----r show."The next day, Delacroix and his assistant Sloan Hopkins (Jada Pinkett Smith) talk. They've decided that Manray is the solution to his problem. Delacroix plans to write a show that will be so "offensive and racist," it will prove his point that the network only wants to see black buffoons on the air. Delacroix simply hopes to be fired, so he can be let go of his contract with CNS. Manray and Womack ask at the receptionist's desk for a "Delapoint" and the men working there tell them to step outside. However, Sloan steps into the lobby, sees what's happening, and escorts Manray and Womack to Delacroix's office. Delacroix explains to them that he has an idea for a television pilot, and they can make money with it. His main request is that Manray changes his name to Mantan, in an apparent homage to black character actor Mantan Moreland.On Sloan's walk home, she runs into her big brother Big Blak Afrika F/K/A Julius (Yasiin Bey). In Sloan's apartment, Julius and Sloan argue about his values, and he tells her to introduce him and his political hip-hop crew, the Mau Maus, to Delacroix.Delacroix has another meeting with Dunwitty. Delacroix proposes that the network start a variety show called "Mantan: The New Millenium Minstrel Show." Delacroix says that new faces are needed for the show, and has Sloan bring in Manray and Womack. The two men, respectively renamed "Mantan" and "Sleep'n Eat," will exhibit a range of stereotypical traits, Delacroix explains. Sloan is opposed to the proceedings, and suggests that there will be protest of the show they are planning. To seal the package, Manray dances atop a table in front of Dunwitty -- who immediately leaves to try to sell the show's concept to his executive bosses.Delacroix, Sloan and another woman hold auditions for the show. The first group of people (The Roots) audition to be the show's house band, The Alabama Porch Monkeys. After they perform, a dancer, a vulgar man shouting "I be smackin' my hoes," and a didgeridoo player all audition. The next hopeful is Honeycutt (Thomas Jefferson Byrd), an actor who bungles Shakespearean quotes and proclaims "N----s is a beautiful thing." Sloan's brother's group, the Mau Maus then do a fiery, confrontational performance; Pierre states via voice over that there is no place for them in his plan.Delacroix looks over a revised script for the show and confronts Dunwitty and his co-writer, Jukka about their alterations to it that even he finds racially offensive. Delacroix says that he won't be responsible for their changes, which Dunwitty says are to make the show funnier. Dunwitty says he knows black people better than Delacroix does, telling him, "Look 
 Question: Who is Delacroix's personal assistant?
answer:

sloan hopkins