You are given a background paragraph that describes one or more causal or qualitative relationships such as a relationship in economics or a scientific law and a story that makes use of the concepts or the relationship described in the provided paragraph. You need to come up with a question about the story that requires an understanding of the relationship described in the background paragraph. The generated question should not be answerable without both the background and story. Write a question about the story that requires a relationship in the background paragraph to answer. Check whether your question requires both the background paragraph and the story to answer. If your question can be answered by only one of these, try to rewrite your question so that it requires both. Note that "flipping" a word in the question can give rise to a new question where the answer will be different from the original question. Often, "flipping" a word gives rise to flipping the direction of the relationship, for example, from "increase" to "decrease."
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Question: Background Paragraph: The primary role of red blood cells in the circulatory system is to transport oxygen to the tissues. The actual carrier of oxygen molecules is the protein hemoglobin, which binds to the oxygen and moves it throughout the body, releasing it in areas where the concentration of dissolved oxygen is low. A certain mutation in the gene for hemoglobin causes a slight change in the structure of this crucial protein, resulting in a disease called sickle-cell anemia. For people with this mutation, the hemoglobin produced by their red blood cells has a tendency to clump together, distorting the shape of the red blood cells and giving rise to the crescent-shaped cells seen above. By understanding the changes in structure that are the underlying cause of this disease, we have developed various ways to treat and manage this illness. 
Story: Doctor Jones studied two teams of workers. Team one had healthy people with normal red blood cell levels, but team two had people with sickle-cell anemia. the differences in health parameters were amazing and obvious.

Answer: Which team didn't have people with crescent shaped cells in their blood?


Question: Background Paragraph: Another example of negative feedback has to do with blood glucose levels. When glucose (sugar) levels in the blood are too high, the pancreas secretes insulin to stimulate the absorption of glucose and the conversion of glucose into glycogen, which is stored in the liver. As blood glucose levels decrease, less insulin is produced. When glucose levels are too low, another hormone called glucagon is produced, which causes the liver to convert glycogen back to glucose. 
Story: A doctor named Phil is researching how sugar affects the body. He noted when his participants ate a lot of sugar their livers would produce a lot more insulin than usual. The insulin would convert the sugar into glycogen. When they had a normal amount of sugar the amount of insulin was stable. He then had a person not eat at all and he found another hormone called glucagon was being produced. This hormone was converting the glycogen back into glucose, also known as sugar.

Answer: Which is an indicator that a person has not eaten in a long time, having more insulin or having more glycogen?


Question: Background Paragraph: Sugaring is a food preservation method similar to pickling. Sugaring is the process of desiccating a food by first dehydrating it, then packing it with pure sugar. This sugar can be crystalline in the form of table or raw sugar, or it can be a high sugar density liquid such as honey, syrup or molasses.

The purpose of sugaring is to create an environment hostile to microbial life and prevent food spoilage. Sugaring is commonly used to preserve fruits as well as vegetables such as ginger. From time to time sugaring has also been used for non-food preservations. For example, honey was used as part of the mummification process in some ancient Egyptian rites.

A risk in sugaring is that sugar itself attracts moisture. Once a sufficient moisture level is reached, native yeast in the environment will come out of dormancy and begin to ferment the sugars into alcohol and carbon dioxide. This leads to the process of fermentation. Although fermentation can be used as a food preservation method, it must be intentionally controlled, or the results will tend to be unpleasant. 
Story: Greg has decided he would like to store some foods for the winter. He has decided to use two different methods to preserve his food. First, he decides to use a process called sugaring, the next he just stores the food in a jar.

Answer:
What method has a higher likely hood of fermentation if moisture is introduced?