Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Input: Consider Input: Context: Chronic myeloid leukemia (CML) is characterized by the presence of the Philadelphia chromosome, which is associated with a balanced translocation involving chromosomes 9 and 22 to produce a fusion gene (bcr-abl) that gives rise to a constitutively activated Abl tyrosine kinase. This kinase led to the discovery of several small-molecule inhibitors, imatinib being the first and most successful of these. Resistance to imatinib results in some patients from Abl kinase point mutations. Overcoming imatinib resistance represents one of the biggest challenges facing clinicians in the modern management of CML. In this review, we discuss the current understanding of CML pathophysiology and mechanisms of imatinib resistance and how advancing this knowledge has led to the design of novel therapies in the area of blastic phase CML and Philadelphia chromosome-positive acute lymphoblastic leukemia with previous imatinib failure. 
 Question: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?

Output: bcr-abl


Input: Consider Input: Context: An electric transformer is a device that uses electromagnetic induction to change the voltage of electric current. Electromagnetic induction is the process of generating current with a magnetic field. It occurs when a magnetic field and electric conductor, such as a coil of wire, move relative to one another. A transformer may either increase or decrease voltage. You can see the basic components of an electric transformer in the Figure 1.1. Click image to the left or use the URL below. URL: The transformer in the diagram consists of two wire coils wrapped around an iron core. Each coil is part of a different circuit. When alternating current passes through coil P, it magnetizes the iron core. Because the current is alternating, the magnetic field of the iron core keeps reversing. This is where electromagnetic induction comes in. The changing magnetic field induces alternating current in coil S of the other circuit. Notice that coil P and coil S in the Figure 1.1 have the same number of turns of wire. In this case, the voltages of the primary and secondary currents are the same. Usually, the two coils of a transformer have different numbers of turns. In that case, the voltages of the two currents are different. When coil S has more turns than coil P, the voltage in the secondary current is greater than the voltage in the primary current (see Figure 1.2). This type of transformer is called a step-up transformer. Thats because it steps up, or increases, the voltage. When coil S has fewer turns of wire than coil P, the voltage in the secondary current is less than the voltage in the primary current (see Figure 1.3). This type of transformer is called a step-down transformer because it steps down, or decreases, the voltage. Q: Both step-up and step-down transformers are used in the electrical grid that carries electricity from a power plant to your home. Where in the grid do you think step-down transformers might be used? A: One place that step-down transformers are used is on the electric poles that supply current to homes. They reduce the voltage of the electric current before it enters home circuits. 
 Question: an electric transformer contains

Output: an iron core.


Input: Consider Input: Context: Count Lasher entered some of the music competitions held regularly at Jamaica's Ward's Theatre. 
 Question: Which country's citizen was Count Lasher?


Output: jamaica