This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

Input: Consider Input: Gene nomenclature has been established by the HUGO Gene Nomenclature Committee (HGNC) for each known human gene in the form of an approved gene name and symbol (short-form abbreviation), which can be accessed through a database maintained by HGNC. Symbols are chosen to be unique, and each gene has only one symbol (although approved symbols sometimes change). Symbols are preferably kept consistent with other members of a gene family and with homologs in other species, particularly the mouse due to its role as a common model organism.

Output: What committee has established gene nomenclature for every known human gene?


Input: Consider Input: The emergence of Susa as a city, as determined by radiocarbon dating, dates back to early 4,395 BC. There are dozens of prehistoric sites across the Iranian plateau, pointing to the existence of ancient cultures and urban settlements in the 4th millennium BC. During the Bronze Age, Iran was home to several civilizations including Elam, Jiroft, and Zayande River. Elam, the most prominent of these civilizations, developed in the southwest of Iran, alongside those in Mesopotamia. The emergence of writing in Elam was paralleled to Sumer, and the Elamite cuneiform was developed since the 3rd millennium BC.

Output: What ancient city dates back as early as 4395 BC in Iran?


Input: Consider Input: It is remarkable that the inner heartwood of old trees remains as sound as it usually does, since in many cases it is hundreds, and in a few instances thousands, of years old. Every broken limb or root, or deep wound from fire, insects, or falling timber, may afford an entrance for decay, which, once started, may penetrate to all parts of the trunk. The larvae of many insects bore into the trees and their tunnels remain indefinitely as sources of weakness. Whatever advantages, however, that sapwood may have in this connection are due solely to its relative age and position.


Output: What do broken limbs and deep wounds open a door for in a tree?