TASK DEFINITION: Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.
PROBLEM: The study to be published on Wednesday in the Journal of Neuroscience differs from many other pot-related research projects that are focused on chronic, heavy users of cannabis. The collaborative effort between Northwestern University’s medical school, Massachusetts General Hospital and Harvard Medical School showed a direct correlation between the number of times users smoked and abnormalities in the brain. “What we’re seeing is changes in people who are 18 to 25 in core brain regions that you never, ever want to fool around with,” said co-senior study author Dr. Hans Beiter, professor of psychiatry and behavioral sciences at Northwestern University. In particular, the study identified changes to the nucleus accumbens and the nucleus amygdala, regions of the brain that are key to regulating emotion and motivation, in marijuana users who smoke between one and seven joints a week. The researchers found changes to the volume, shape and density of those brain regions. But more studies are needed to determine how those changes may have long-term consequences and whether they can be fixed with abstinence, Beiter said. “Our hypothesis from this early work is that these changes may be an early sign of what later becomes amotivation, where people aren’t focused on their goals,” he said. The study, which was funded in part by the National Institute on Drug Abuse and the White House Office of National Drug Control Policy, comes as access to pot is expanding following 2012 votes in Washington state and Colorado to legalize its recreational use. The drug remains illegal under federal law. Medical pot is allowed in 20 U.S. states. Pot legalization advocates make the argument that marijuana is safer than alcohol a central part of their campaigns. Other research has found drinking alcohol alters the brain, Beiter said. But while researchers do not know exactly how the mental rewiring seen in pot users affects their lives, the study shows it physically changes the brain in ways that differ from drinking, he said. This latest study fits with other research showing marijuana use has significant effects on young people because their brains are still developing, and Beiter said he has become convinced that marijuana should only be used by people under 30 if they need it to manage pain from a terminal illness.

SOLUTION: Casual pot use causes brain abnormalities in the young: study.

PROBLEM: A meme showing a picture of a doctor and the paramedic who saved each others lives has long circulated on social media, in large part due to an April 2016 Unbelievable Facts Facebook post:That meme read at the bottom:In 1981, a pediatrician saved the life of a 3.2-pound premature baby boy by working around the clock to beat the odds & stabilize him. In 2011, the pediatrician was pinned inside a burning vehicle after a car collision, but was saved by the premature baby, who had grown up to become a paramedic.An identical version was shared on November 22 2019 to r/nevertellmetheodds, a subreddit for posts about long-odds scenarios occurring in real life:What goes around comes around from nevertellmetheoddsThe story (and appended photograph) originated with a March 2015 KTLA report about the doctor and the once-premature baby — Dr. Michael Shannon and Chris Trokey — reuniting at a fundraiser four years after Trokey saved Shannon’s life in 2011:Exactly four years ago, on March 29, 2011, Dr. Michael Shannon was driving on Pacific Coast Highway in Dana Point when a semi-truck T-boned his SUV, pinning his vehicle underneath the truck as it caught fire.Firefighters from Paramedic Engine 29 were returning from another call and responded within minutes to the fiery crash.By the time they arrived, Shannon’s vehicle was also ablaze and the flames were burning his legs. Fire crews then worked to extinguish the flames and rescue him using the Jaws of Life.The seriously injured Shannon was taken to Mission Hospital in Mission Viejo where he spent the next 45 days recovering from internal injuries. He also had to have two of his toes amputated.Among those who had helped save Shannon that day was Orange County Fire Authority paramedic Chris Trokey, whose own life had been saved 30 years earlier by the pediatrician.“I didn’t know about until I went to the hospital and started talking about it, Dr. Shannon. And I was like, ‘Oh my gosh, Dr. Shannon? '” Trokey recalled [in 2015]. “That’s when I found out.”KTLA added:Trokey was just 3.2 pounds at birth, and doctors had initially gave him a 50/50 chance at surviving. But his pediatrician — Dr. Shannon — helped save his life, staying with the infant around the clock until his health improved and he was stable.According to the meme, a pediatrician (Shannon) saved a premature baby (Trokey) in 1981. Thirty years later, the then-grown baby was a paramedic, and a first responder to a serious car accident involving Shannon. When Shannon and Trokey met again in 2015, KTLA reported the story, inspiring memes which circulated for several years thereafter.

SOLUTION: In 1981, a pediatrician saved the life of a 3.2-pound premature baby boy by working around the clock to beat the odds & stabilize him. In 2011, the pediatrician was pinned inside a burning vehicle after a car collision, but was saved by the premature baby, who had grown up to become a paramedic.

PROBLEM: There was no discussion of costs. Were people to begin taking B vitamins in the quantities necessary to show improvement along the lines of what has been seen in some of the studies mentioned, B vitamins could become a lifelong treatment with significant cumulative costs. The slant of the story was to question the wisdom in augmenting vitamin B intake in light of the studies failing to demonstrate benefit. The story itself, however, reported on several pieces of evidence over time rather than reporting on the results of a specific study or studies. Where it did provide numbers on benefits, it did so in a clear and cautious way. For example, it noted “a recent study in which brain atrophy (or shrinkage, which occurs in older people who are losing brain function) slowed by 30% in elderly patients with both high homocysteine levels and mild cognitive impairment who took a B vitamin pill daily for two years. Brain shrinkage occurred at a rate of about 0.75% in the people taking B vitamins in the study, compared with a rate of 1.1% per year in a group that took a placebo.” By including the actual percentages for people in both groups, the story shows the reader that the shrinkage was not dramatic to begin with and that the difference between the two groups could also be described as a 0.26 percentage point difference. The story did include information about possible side effects and harms associated with excessive consumption of B vitamins. The story provided a reasonable description of several studies in which outcomes were not changed with vitamin B supplementation. There was a useful quote by one of the researches indicating that only a minority of studies showed any indication of benefit from increasing vitamin B intake. We wish it had taken a little more care in making clear distinctions between the different populations being studied. In some cases, the studies were focused on anyone of advanced age, while in others they were focused specifically on Alzheimer’s patients, but there was no discussion in the story about whether these differences may also have accounted for the different findings among the studies. The story did not engage in disease mongering. The story detailed several studies of the relation between the B vitamins and cognitive impairment; it included quotes from two researchers  (Haan and Miller) in the field who are at different institutions but have several studies that they have worked on and published together. There was no discussion of how the fortification of common foods in the supply chain, such as grains, flour, cereal, energy bars and drinks, has affected the levels of B vitamin. There was also no mention of other specific therapies to stop cognitive decline. The story described the urge to rush out and purchase B vitamins, which is suggestive of their ready availability. The story neglected to mention that many foods are already fortified with B vitamins, which may already cover the recommended intake levels for many readers. This story provided a nice overview of what is known about B vitamins in relation to age- and disease- related cognitive decline. The story does not appear to rely solely on a news release. It is not clear why this information about the long-term research interest of two local scientists is news right now, but it is an interesting piece nonetheless.

SOLUTION:
Vitamin B and its role in improving memory