Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.
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Question: Tuberculosis is North Korea’s biggest public health problem. With this American-made machine, his lab would be able to complete a TB test in just two hours, instead of two months. It took years, but Dr. O got the machines, only to discover that GeneXpert needs cartridges he can’t replace. It’s not entirely clear what about the cartridges would violate international sanctions. For a long time, the producer refused to disclose what agents were inside because that was patented information. But it doesn’t really matter. No one, it seems, is willing to help him procure them from abroad and run the risk of angering Washington. Despite a budding mood of detente on the Korean Peninsula since the summit between President Donald Trump and North Korean leader Kim Jong Un last month in Singapore, ongoing sanctions championed by the U.S. and Trump’s “maximum pressure” policy continue to generate an atmosphere of hesitation and the fear of even unintentional violations. And that is keeping lifesaving medicines and supplies from thousands of North Korean tuberculosis patients. Dr. O’s laboratory, built with help from Stanford University and Christian Friends of Korea aid group, has essentially been running on empty since April. But the idle GeneXperts may soon be the least of his troubles. ___ Tuberculosis kills more than 1.6 million people a year. When left untreated it will be fatal in half of those it infects. It’s the world’s most deadly infectious disease and is so contagious that each case can be expected to lead to 10 to 20 more. In developed countries, it has largely been brought under control. There’s a vaccine that prevents it and a cocktail of drugs that can be used to treat, and often cure, it in a matter of months. But it’s a major scourge in less affluent places, including North Korea and sub-Saharan Africa. To help North Korea control its tuberculosis problem, a Geneva-based international aid organization called the Global Fund to Fight AIDS, Tuberculosis and Malaria has dispersed more than $100 million in grants since 2010. Last year it supported the treatment of about 190,000 North Korean TB patients. But, two weeks ago, Global Fund ended all of its North Korea-related grants, saying it could no longer accept the North’s “unique operating conditions.” Spokesman Seth Faison said the fund informed Pyongyang in February so it would have time to look for alternative funding sources. He said Global Fund is providing buffer stocks of medicines and health products to help support the treatment of tuberculosis patients through June next year. Faison said Global Fund welcomes the “positive diplomatic efforts underway” between Pyongyang and its neighbors. But the fund’s position stands. The decision shocked the doctors at the Pyongyang tuberculosis lab, who praised Global Fund for the work it had done but accused it of bowing to political pressure from the United States and Trump’s vow to keep the pressure on and not ease sanctions until the North makes major steps toward denuclearization. The United States government, which has pledged $1.4 billion this year, is one of Global Fund’s biggest donors. The fund’s retreat sparked outrage outside of North Korea as well. In an open letter published in the medical journal Lancet, Harvard physician Kee Park, director of North Korea programs for the Korean American Association, warned the fund’s withdrawal could create a “humanitarian and public health crisis” and called the move “a cataclysmic betrayal of the people of the DPRK.” Whatever the reason, its departure is valid cause for concern. When tuberculosis patients reduce or go off their medications prematurely, or begin taking lower quality ones, the bacteria that causes their disease can develop a resistance to the two most powerful anti-TB drugs, making the condition harder and much more expensive to treat. This kind of multi-drug resistant TB is most often found in China, India and Russia. And it’s a big problem in North Korea. ___ North Korea’s health system is fragile and strapped for resources. But in keeping with Kim’s directives to lift the nation’s standard of living, officials are looking for ways to improve. “We have been waging a vigorous struggle with a highly ambitious plan to increase the average life expectancy of the population and bring other health indices in line with those of the world’s most advanced countries,” explained Ri Jong Chang, who is the director of the Central Tuberculosis Prevention Institute and has worked with TB patients for the past 25 years. Ri explained that at the most basic level, the country maintains a network of about 7,000 clinics and a system initiated decades ago that focuses on “household doctors.” Each doctor is responsible for the care of 150 households within their administrative area. Along with primary care, they keep their patients informed and educated about health issues and conduct activities to prevent diseases. If a suspected case of tuberculosis is found, the patient is sent to a county-level hospital for testing. Aware of its needs and vulnerabilities, North Korea, which is generally secretive and deeply suspicious of anything that smacks of foreign “meddling,” has demonstrated a surprising willingness to accept help, allow access and share information with United Nations’ agencies and foreign aid organizations. Along with Global Fund, the most established group treating TB patients in the North is the Eugene Bell Foundation, which supports the treatment of more than 1,000 patients at 12 centers across the country. Unlike Global Fund, since 2008 the Eugene Bell Foundation has been solely focused on fighting multi drug-resistant tuberculosis, which typically takes about 18 months to treat and costs nearly $5,000 per patient. Stephen Linton, who founded the group in 1995, has a grim assessment of the situation. “We are probably only covering about one-tenth of the MDR-TB patients in the country right now,” he told The Associated Press. He said about half of his patients are in Pyongyang, a city of 3 million and the place where most of the North’s elites reside. The reason is straightforward — MDR-TB develops after exposure to medications that failed. In rural areas, fewer people have access to those medicines to begin with. “If you are living in the countryside in North Korea, you are much less likely to get MDR-TB than if you live in Pyongyang. It’s horrendous,” he said. “We can’t get to the bottom of it, even though we focus a lot of resources there.” What really worries him, and the North Korean government, is what will happen if the patients who relied on Global Fund support run out of medications, stop getting help or turn to cheaper, less effective treatments. Many will die. But not before infecting many others. “This is an airborne infection,” he said. “Every time you are in a closed space with a TB patient, you are at risk. So for all the people that travel to North Korea, all the tourists, all the diplomats — they are a risk to everyone who comes near them.” ___ This was supposed to be the year Eugene Bell began to really up its game in North Korea, tripling to 3,000 the number of patients it treats. Many of the sanatoria where TB patients are treated in the North were built 30 or 40 years ago. They have poor insulation, are overcrowded and are often fire hazards. To address those problems and the sort of transparency issues Global Fund was concerned about, Eugene Bell has developed pre-fabricated wards tailor-made to meet the North’s conditions. They are simple, single-story duplexes. Each can be put up quickly by three or four people, meaning the entire process can be monitored while Linton and other Eugene Bell people are in the country on their bi-annual medical team visits. The wards are already paid for when they are shipped from China, so the money isn’t going into the pockets of government officials or funding Kim Jong Un’s missile programs. The idea was to begin putting up 80-100 wards to create large centers in each of North Korea’s nine provinces. A pilot project with 10 wards is now operating on the outskirts of Pyongyang, not far from the airport. Linton said everything was going well until last December. “Then we ran into this sanctions problem,” he said. “It’s officially approved. The design is approved. And it’s not that we can’t send anything in. But these buildings have a metal roof — a panel that has metal in it, aluminum — and that’s the issue.” Linton said Eugene Bell has a quarter of a million dollars’ worth of them “rotting in monsoon weather” in a dockyard outside of Seoul. He believes that until Washington makes it clear it is not against humanitarian aid, other countries and aid organizations will be reluctant to act — or even approve the shipment of items like Dr. O’s GeneXpert cartridges or Eugene Bell’s patient wards that are clearly intended for humanitarian use. As an American, Linton says, he is concerned the U.S. will be held responsible for whatever bad happens with TB in North Korea since no country is as seen as “owning” the sanctions as much as America. “Unless something is done and done soon, this medical emergency will become known in Korea as the ‘Sanctions TB Epidemic,’” he said. “And it will haunt the peninsula for generations.” ___ Talmadge is the AP’s Pyongyang bureau chief. Follow him on Instagram and Twitter: @EricTalmadge

Answer: Despite detente, sanctions on North Korea fan TB epidemic.


Question: The study to be published on Wednesday in the Journal of Neuroscience differs from many other pot-related research projects that are focused on chronic, heavy users of cannabis. The collaborative effort between Northwestern University’s medical school, Massachusetts General Hospital and Harvard Medical School showed a direct correlation between the number of times users smoked and abnormalities in the brain. “What we’re seeing is changes in people who are 18 to 25 in core brain regions that you never, ever want to fool around with,” said co-senior study author Dr. Hans Beiter, professor of psychiatry and behavioral sciences at Northwestern University. In particular, the study identified changes to the nucleus accumbens and the nucleus amygdala, regions of the brain that are key to regulating emotion and motivation, in marijuana users who smoke between one and seven joints a week. The researchers found changes to the volume, shape and density of those brain regions. But more studies are needed to determine how those changes may have long-term consequences and whether they can be fixed with abstinence, Beiter said. “Our hypothesis from this early work is that these changes may be an early sign of what later becomes amotivation, where people aren’t focused on their goals,” he said. The study, which was funded in part by the National Institute on Drug Abuse and the White House Office of National Drug Control Policy, comes as access to pot is expanding following 2012 votes in Washington state and Colorado to legalize its recreational use. The drug remains illegal under federal law. Medical pot is allowed in 20 U.S. states. Pot legalization advocates make the argument that marijuana is safer than alcohol a central part of their campaigns. Other research has found drinking alcohol alters the brain, Beiter said. But while researchers do not know exactly how the mental rewiring seen in pot users affects their lives, the study shows it physically changes the brain in ways that differ from drinking, he said. This latest study fits with other research showing marijuana use has significant effects on young people because their brains are still developing, and Beiter said he has become convinced that marijuana should only be used by people under 30 if they need it to manage pain from a terminal illness.

Answer: Casual pot use causes brain abnormalities in the young: study.


Question: "The New England Patriots might wish this entire business of under-inflated footballs would vanish in a puff of smoke, but it’s a boon for physics teachers who have found themselves suddenly relevant in the world of sports. Patriots coach Bill Belichick, a self-declared non-scientist, held a pre-Super Bowl news conference where he attempted to explain why a football inflated indoors would lose pressure after being used outside. ""When the footballs are delivered to the officials' locker room, the officials were asked to inflate them to 12.5 pounds per square inch. What exactly they did, I don’t know,"" Belichick said. ""When the footballs go out on to the field into game conditions ...  That’s where the measurements would be different than what they are, possibly different, than what they are in a controlled environment."" Belichick said when Patriot staffers tested this, they found that the balls ""were down approximately one-and-a-half pounds per square inch."" There are too many unknowns to resolve Deflategate, as this flap is called. But we couldn't help but give Belichick's main assertion the PunditFact treatment. The question in this case is what physics tells us about Belichick’s point. Could conditions outside (basically temperature and humidity) bring down the pressure of a football by about 1.5 pounds per square inch? A quick recap The Patriots advanced to the Super Bowl on Jan. 18, 2015, by defeating the Indianapolis Colts 45-7. But by the next day, the most interesting number wasn’t the point spread, but the inflation pressure of the Patriots’ footballs. Under NFL rules, each team provides 12 balls, and about two hours before the game, an official verifies that they are inflated to the regulation pressure range of 12.5 to 13.5 pounds per square inch. At half-time, the NFL re-checked the Patriots’ footballs -- reportedly at the request of the Colts but there’s a bit of conflicting information on this -- and found 11 of the 12 were under inflated. By how much? That’s unclear. Some reports say by 2 pounds per square inch. Others say while one ball might have measured that low, the rest were only about 1 pound under. One other essential variable: The temperature on game day was around 50 degrees. No one knows the exact inside temperature. Most people assume it was about 70 degrees. Doing the math After Belichick spoke, ABC News turned to Bill Nye, the popular explainer of all things scientific, to assess the coach’s claim. ABC played up Nye's verdict that Belichick's words ""didn’t make any sense,"" but from the video, it sounds as though Nye was talking about Belichick's claim that rubbing the footballs would change the pressure, not the impact of temperature. CBS Sports relayed a tweet from another science luminary, physicist Neil deGrasse Tyson who also expressed skepticism. ""For the Patriots to blame a change in temperature for 15 percent lower-pressures, requires balls to be inflated with 125-degree air,"" Tyson wrote. CBS reported that ""Every 10 degree drop in temperature (F) results in about .2 PSI loss in a football."" According to CBS, that meant the weather would account for just a 0.4 pound of pressure loss, and tied that conclusion, loosely, to an Ohio State University physicist. We’ll get back to that CBS story (and its flaws) in a bit. On the other side of the ledger, USA Today interviewed Bowdoin College physics professor Dale Syphers who declared that a drop from room temperature in the 70s down to 40 degrees would reduce the pressure in a football by 1.3 pounds per square inch. The Daily Beast turned to the chair of the Physics Department at Boston College who said that with a 30 degree drop in temperature -- 75 down to 45 degrees -- you would expect the ball pressure to fall by by 1.54 pounds per square inch. Finally, the world of physics is divided between the theoretical physicists and the experimentalists. The physicists cited in the news worked with formulas. HeadSmart Labs, a private firm in Pittsburgh, tested actual footballs. It found that footballs inflated at 75 degrees, then cooled to 50 degrees lost 1.1 pounds of pressure. The lab took one more step. Since it was raining on game day, the staff dampened the balls. This led to a drop of an additional 0.7 pounds of pressure for a total of at least 1.8 pounds per square inch. The physics teachers come off the bench Enter Robert Hilborn of the American Association of Physics Teachers. The Harvard-trained physicist showed in detail how a law of physics, the ideal gas law, applied to the Patriots’ footballs. When a gas cools, it contracts. The ideal gas law helps us put numbers to that relationship between pressure and temperature. Math alert: We’re going to show you pretty much everything, so you can do it yourself at home. ""As almost every chemistry and physics student knows, the ideal gas law tells us that Pf = Pi (Tf/Ti),"" Hilborn wrote. The final pressure Pf equals the initial pressure Pi times the final temperature divided by the initial temperature Tf/Ti. Plugging in the numbers is simple, so long as you keep two things in mind. First, the pressure isn’t the pressure you see on your pressure gauge. It’s that amount plus the pressure of the atmosphere that’s all around you. It might feel counterintuitive, but when a football comes off the assembly line, before it's ever pumped up, it actually has an internal pressure that you wouldn't notice because it's the same as the pressure we always ignore. That's the pressure that comes from all those miles of air in our atmosphere pushing down on us. That pressure averages around 14.7 pounds per square inch. When you pump air into the football, you are adding pressure on top of the 14.7 that are already there. In Hilborn's math, you'll see he's added in the atmospheric pressure. The other key step is to measure the temperature in Celsius and count from absolute zero. That’s the Kelvin scale. Hilborn used a starting temperature of 70 degrees and a final temperature of 50 degrees Fahrenheit and a starting pressure of 12.5 pounds per square inch. ""Those numbers give us 27.2 psi for Pi, 294 K for Ti, and 283 K for Tf resulting in Pf = 26.2 psi for the total pressure and a corresponding gauge pressure of 11.5 psi, about 1 psi below the NFL lower limit."" In short, taking the balls outside would bring the pressure down 1 pound per square inch. Hilborn then accounted for the rain that day. Cooling the moist air inside the footballs would shed another 0.2 pounds per square inch. ""Combining the air temperature change effect with that of water vapor gives us a total of 1.2 psi, not too far from the figure of 1.4 psi given in one of the early NFL statements,"" Hilborn wrote. Hilborn’s results are pure math, and they are largely in line with the test results from the lab in Pittsburgh. The results in other news reports We were troubled by the CBS item that came up with a much lower number of 0.4 pounds per square inch due to a lower outdoor temperature. But when we called Prof. Michael Lisa, the Ohio State University physicist quoted in the CBS article, Lisa said, ""CBS got it wrong."" Lisa sent us this chart that you can download showing that for each 10 degrees drop in temperature, pressure drops 0.5 pounds. (The chart’s different lines show that the higher the starting pressure, the greater the impact of falling temperature.) We found that news reports that undercut the Patriots’ explanation used a high number for the loss of pressure. CBS said the footballs lost 2 pounds of pressure. Ditto for a Toronto Sun article. If it turns out that there really was a loss that large, then those arguments hold up. For the moment, we are simply assessing whether the physics back up what Belichick said and he used the 1.5 pound figure. Lisa also affirmed Hilborn’s analysis. ""That AAPT guy did a nice job,"" Lisa said. Nevertheless, Hilborn himself said no one should rush to judgment. ""A conservative conclusion is that temperature changes alone can account for much of the under-inflation,"" Hilborn wrote. ""But until more accurate information is available about the preparation of and measurement of the footballs’ air pressure, we should not assert that conclusion with a great deal of certainty."" The NFL is investigating and at some point, all the numbers might be known. Or not. Hilborn told PunditFact that the accuracy of the pressure gauges is unclear. One number that will be of interest is the starting pressure for the Colts’ footballs. It's possible they may have deflated as well, but stayed within the legal limits. Our ruling Belichick said that moving the footballs from indoors to outdoors could explain the loss of about 1.5 pounds per square inch of pressure. Experimental and mathematical results are in that ballpark. Lab tests said air temperature alone could bring down the pressure by 1.1 pounds. The ideal gas law predicted a 1 pound loss. The rain that day would explain at least another 0.2 pound shift and possibly as much as 0.7. We lack firm numbers on the actual pressure drop in the Patriots footballs, as well as precise information on the starting and ending temperatures. Within the limits of what the physics alone can tell us at this point, the math gets us pretty close to what Belichick said. With allowances for the uncertain data."

Answer:
"Atmospheric conditions could push a football’s pressure ""down approximately one-and-a-half pounds per square inch."