In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

Q: Paragraph: Background: The World Health Organization recommends periodic evaluations of influenza surveillance systems to identify areas for improvement and provide evidence of data reliability for policymaking. However, data about the performance of established influenza surveillance systems are limited in Africa, including in the Democratic Republic of Congo (DRC). Methods: We used the Centers for Disease Control and Prevention guidelines to evaluate the performance of the influenza sentinel surveillance system (ISSS) in DRC during 2012-2015. The performance of the system was evaluated using eight surveillance attributes: (i) data quality and completeness for key variables, (ii) timeliness, (iii) representativeness, (iv) flexibility, (v) simplicity, (vi) acceptability, (vii) stability and (viii) utility. For each attribute, specific indicators were developed and described using quantitative and qualitative methods. Scores for each indicator were as follows: < 60% weak performance; 60-79% moderate performance; ≥80% good performance. Results: During 2012-2015, we enrolled and tested 4339 patients with influenza-like illness (ILI) and 2869 patients with severe acute respiratory illness (SARI) from 11 sentinel sites situated in 5 of 11 provinces. Influenza viruses were detected in 446 (10.3%) samples from patients with ILI and in 151 (5.5%) samples from patients with SARI with higher detection during December-May. Data quality and completeness was > 90% for all evaluated indicators. Other strengths of the system were timeliness, simplicity, stability and utility that scored > 70% each. Representativeness, flexibility and acceptability had moderate performance. It was reported that the ISSS contributed to: (i) a better understanding of the epidemiology, circulating patterns and proportional contribution of influenza virus among patients with ILI or SARI; (ii) acquisition of new key competences related to influenza surveillance and diagnosis; and (iii) continuous education of surveillance staff and clinicians at sentinel sites about influenza. However, due to limited resources no actions were undertaken to mitigate the impact of seasonal influenza epidemics. Conclusions: The system performed overall satisfactorily and provided reliable and timely data about influenza circulation in DRC. The simplicity of the system contributed to its stability. A better use of the available data could be made to inform and promote prevention interventions especially among the most vulnerable groups. 
 Title: Evaluation of the influenza sentinel surveillance system in the Democratic Republic of Congo, 2012-2015

A: True
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Q: Paragraph: The development and use of numerous animal models of human autoimmune diseases have provided important advances in our understanding of pathogenic mechanisms of disease and provided robust and reliable models to test novel therapeutic strategies. However, few preclinical studies of therapeutic treatments have demonstrated efficacy in the clinic, possibly because of the biological differences between humans and other animals. Although animal models of human disease are imperfect, it is important to understand the differences between the human disease and its animal models and to design experimental studies using animal models appropriately for the questions being asked. This review provides an overview of the currently used animal models of three human neuroimmunological diseases, multiple sclerosis, Guillain-Barré syndrome, and myasthenia gravis, as well as the advantages and disadvantages of each model and how they correlate or differ from their human counterpart. 
 Title: Animal Models for the Study of Neuroimmunological Disease

A: True
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Q: Paragraph: Microglia and macrophages are related cell types that play an important role in the pathogenesis of MS and EAE. This chapters reviews the role of these cells in the normal brain and their contribution to inflammatory demyelinating disease, including their role in antigen presentation, co-stimulation, and production of cytokines and other inflammatory mediators The microglia, a brain-resident, non-neuronal cell and the blood-derived or haematogenous macrophage represent two related cell types involved in key events in the development of pathology in Multiple Sclerosis and its autoimmune animal model, the Experimental Allergic Encephalomyelitis. Microglia and macrophages fulfil a variety of different functions, but they are also recognized for their ability to act as a particularly fine sensor of brain pathology. Both cell types are rapidly activated and recruited to sites of infection, neurodegeneration, stroke, autoimmune inflammatory models such as EAE and its presumptive human counterpart, multiple sclerosis. Microglia and macrophages are stimulated by a variety of cytokines, neurotransmitters, modulators and putative neurotoxins, extracellular matrix molecules and proteases present in the inflamed central nervous system. Moreover, both cell types are plastic in their morphology and cellular identity. The presence of dying cells and cell debris will cause a transformation of phagocytic microglia into a detached, rounded and migratory or amoeba-like (amoeboid) macrophage (Streit et al., 1988; Bohatschek et al., 2001). This also works in reverse: surrounded by a CNS environment, non-phagocytic macrophages freshly recruited from the blood stream will gradually develop 
 Title: Chapter A7 ROLE OF MICROGLIA AND MACROPHAGES IN EAE

A:
False
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