In this task, you are given a context, a subject, a relation, and many options. Based on the context, from the options select the object entity that has the given relation with the subject. Answer with text (not indexes).
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Question: Context: The Andes or Andean Mountains are the longest continental mountain range in the world. They are a continuous range of highlands along the western edge of South America. This range is about long, about wide (widest between 18° south and 20° south latitude), and of an average height of about . The Andes extend from north to south through seven South American countries: Venezuela, Colombia, Ecuador, Peru, Bolivia, Argentina and Chile., Caretas (Masks) is a weekly newsmagazine published in Lima, Peru, renowned for its investigative journalism., Investigative journalism is a form of journalism in which reporters deeply investigate a single topic of interest, such as serious crimes, political corruption, or corporate wrongdoing. An investigative journalist may spend months or years researching and preparing a report. Investigative journalism is a primary source of information. Most investigative journalism is conducted by newspapers, wire services, and freelance journalists. Practitioners sometimes use the term "accountability reporting". , Colombia (or ), officially the Republic of Colombia, is a transcontinental country largely situated in the northwest of South America, with territories in Central America. Colombia shares a border to the northwest with Panama, to the east with Venezuela and Brazil and to the south with Ecuador and Peru. It shares its maritime limits with Costa Rica, Nicaragua, Honduras, Jamaica, the Dominican Republic and Haiti. It is a unitary, constitutional republic comprising thirty-two departments. The territory of what is now Colombia was originally inhabited by indigenous peoples including the Muisca, the Quimbaya and the Tairona., Brazil, officially the Federative Republic of Brazil, is the largest country in both South America and Latin America. As the world's fifth-largest country by both area and population, it is the largest country to have Portuguese as an official language and the only one in the Americas. Bounded by the Atlantic Ocean on the east, Brazil has a coastline of . It borders all other South American countries except Ecuador and Chile and covers 47.3% of the continent's land area. Its Amazon River basin includes a vast tropical forest, home to diverse wildlife, a variety of ecological systems, and extensive natural resources spanning numerous protected habitats. This unique environmental heritage makes Brazil one of 17 megadiverse countries, and is the subject of significant global interest and debate regarding deforestation and environmental protection., Peru , officially the Republic of Peru, is a country in western South America. It is bordered in the north by Ecuador and Colombia, in the east by Brazil, in the southeast by Bolivia, in the south by Chile, and in the west by the Pacific Ocean. Peru is an extremely biodiverse country with habitats ranging from the arid plains of the Pacific coastal region in the west to the peaks of the Andes mountains vertically extending from the north to the southeast of the country to the tropical Amazon Basin rainforest in the east with the Amazon river., South America is a continent located in the western hemisphere, mostly in the southern hemisphere, with a relatively small portion in the northern hemisphere. It is also considered a subcontinent of the Americas, which is the model used in nations that speak Romance languages. The reference to South America instead of other regions (like Latin America or the Southern Cone) has increased in the last decades due to changing geopolitical dynamics (in particular, the rise of Brazil)., Doris Gibson Parra del Riego ( 28 April 1910 -- 23 August 2008 ) was a Peruvian magazine writer and publisher . She is most noted as the founder and editor of the Peruvian weekly newsmagazine Caretas . She has been described as `` a feminist before the movement had begun , and according to many , a visionary who influenced the course of Peru 's recent history through the brave and defiant reporting of the magazine she created '' ., Bolivia (; ), officially known as the Plurinational State of Bolivia, is a landlocked country located in western-central South America. It is bordered to the north and east by Brazil, to the southeast by Paraguay, to the south by Argentina, to the southwest by Chile, and to the northwest by Peru. One-third of the country is the Andean mountain range, with one of its largest cities and principal economic centers, El Alto, located on the Altiplano. Bolivia is one of two landlocked countries (the other is Paraguay) that lie outside Afro-Eurasia. Bolivia is the largest landlocked country in the Americas., Subject: doris gibson, Relation: occupation, Options: (A) journalism (B) journalist (C) model (D) mountain (E) nicaragua (F) official

Answer: journalist


Question: Context: The genus Psammolestes belongs to the subfamily Triatominae . 3 species : Psammolestes arthuri ( Pinto , 1926 ) ( Tc ) Psammolestes coreodes Bergroth , 1911 Psammolestes tertius Lent & Jurberg , 1965 ( Tc ) ( Tc ) means associated with Trypanosoma cruzi, Triatoma infestans, commonly called winchuka "(vinchuca)" in Argentina, Bolivia and Chile, barbeiro in Brazil and also known as "kissing bug" or "barber bug" in English, is a blood-sucking bug (like all the members of its subfamily Triatominae) and the most important vector of "Trypanosoma cruzi" which can lead to Chagas disease. It is widespread in the Southern Cone countries of South America; that is, in Bolivia, Argentina, Uruguay, Paraguay, Chile, Brazil and Peru. In all these countries "T. infestans" is almost an exclusively domestic species, except in Bolivia where sylvatic forms have been recorded in rock piles in association with wild guinea pigs. This region has joined the control intervention called "Southern Cone Initiative" managed by the PAHO., Rhodnius is a genus of assassin bugs in the subfamily Triatominae (the kissing bugs), and is an important vector in the spread of Chagas disease. The "Rhodnius" species were important models for Sir Vincent Wigglesworth's studies of insect physiology, specifically growth and development., Vertebrates comprise all species of animals within the subphylum Vertebrata (chordates with backbones). Vertebrates represent the overwhelming majority of the phylum Chordata, with currently about 64,000 species described. Vertebrates include the jawless fish and the jawed vertebrates, which include the cartilaginous fish (sharks and rays) and the bony fish. , The Reduviidae are a large cosmopolitan family of the order Hemiptera (true bugs). They are slightly unusual overall, but very common among the Hemiptera because almost all are terrestrial ambush predators (most other predatory Hemiptera are aquatic). The main examples of nonpredatory Reduviidae are some blood-sucking ectoparasites in the subfamily Triatominae. Though spectacular exceptions are known, most members of the family are fairly easily recognizable; they have a relatively narrow neck, sturdy build, and formidable curved proboscis (sometimes called a rostrum). Large specimens should be handled with caution, if at all, because they sometimes defend themselves with a very painful stab from the proboscis., Argentina, officially the Argentine Republic, is a federal republic in the southern half of South America. Sharing the bulk of the Southern Cone with its neighbor Chile to the west, the country is also bordered by Bolivia and Paraguay to the north, Brazil to the northeast, Uruguay and the South Atlantic Ocean to the east, and the Drake Passage to the south. With a mainland area of , Argentina is the eighth-largest country in the world, the second largest in Latin America, and the largest Spanish-speaking one. The country is subdivided into twenty-three provinces (singular "provincia") and one autonomous city ("ciudad autónoma"), Buenos Aires, which is the federal capital of the nation as decided by Congress.
The provinces and the capital have their own constitutions, but exist under a federal system., Rhodnius prolixus is the second most important triatomine vector of the Chagas parasite due to both its sylvatic and domestic populations in northern South America as well as to its exclusively domestic populations in Central America. It has a wide range of ecotopes, mainly savanna and foothills with an altitude of between 500 meters to 1,500 meters (1600 feet to 4,900 feet) above sea level and temperatures of 16 °C to 28 °C (61 °F to 82 °F). Sylvatic "R. prolixus", as virtually all "Rhodnius" spp., is primarily associated with palm tree habitats and has a wide range of hosts including birds, rodents, marsupials, sloths, and reptiles., Trypanosoma cruzi is a species of parasitic euglenoids. Amongst the protozoa, the trypanosomes characteristically bore tissue in another organism and feed on blood (primarily) and also lymph. This behaviour causes disease or the likelihood of disease that varies with the organism: for example, trypanosomiasis in humans (Chagas disease in South America ), dourine and surra in horses, and a brucellosis-like disease in cattle. Parasites need a host body and the haematophagous insect triatomine (descriptions "assassin bug", "cone-nose bug", and "kissing bug") is the major vector in accord with a mechanism of infection. The triatomine likes the nests of vertebrate animals for shelter, where it bites and sucks blood for food. Individual triatomines infected with protozoa from other contact with animals transmit trypanosomes when the triatomine deposits its faeces on the host's skin surface and then bites. Penetration of the infected faeces is further facilitated by the scratching of the bite area by the human or animal host., Triatoma is a genus of assassin bug in the subfamily Triatominae (kissing bugs). The members of "Triatoma" (like all members of Triatominae) are blood-sucking insects that can transmit serious diseases, such as Chagas disease. Their saliva may also trigger allergic reactions in sensitive individuals, up to and including severe anaphylactic shock., Chagas disease, also known as American trypanosomiasis, is a tropical parasitic disease caused by the protozoan "Trypanosoma cruzi". It is spread mostly by insects known as Triatominae or kissing bugs. The symptoms change over the course of the infection. In the early stage, symptoms are typically either not present or mild, and may include fever, swollen lymph nodes, headaches, or local swelling at the site of the bite. After 812 weeks, individuals enter the chronic phase of disease and in 6070% it never produces further symptoms. The other 30 to 40% of people develop further symptoms 10 to 30 years after the initial infection, including enlargement of the ventricles of the heart in 20 to 30%, leading to heart failure. An enlarged esophagus or an enlarged colon may also occur in 10% of people.
"T. cruzi" is commonly spread to humans and other mammals by the blood-sucking "kissing bugs" of the subfamily Triatominae. These insects are known by a number of local names, including: "vinchuca" in Argentina, Bolivia, Chile and Paraguay, "barbeiro" (the barber) in Brazil, "pito" in Colombia, "chinche" in Central America, and "chipo" in Venezuela. The disease may also be spread through blood transfusion, organ transplantation, eating food contaminated with the parasites, and by vertical transmission (from a mother to her fetus). Diagnosis of early disease is by finding the parasite in the blood using a microscope. Chronic disease is diagnosed by finding antibodies for "T. cruzi" in the blood.
Prevention mostly involves eliminating kissing bugs and avoiding their bites. Other preventative efforts include screening blood used for transfusions. A vaccine has not been developed as of 2013. Early infections are treatable with the medication benznidazole or nifurtimox. Medication nearly always results in a cure if given early, but becomes less effective the longer a person has had Chagas disease. When used in chronic disease, medication may delay or prevent the development of endstage symptoms. Benznidazole and nifurtimox cause temporary side effects in up to 40% of people including skin disorders, brain toxicity, and digestive system irritation.
It is estimated that 7 to 8 million people, mostly in Mexico, Central America and South America, have Chagas disease as of 2013. In 2006, Chagas was estimated to result in 12,500 deaths per year. Most people with the disease are poor, and most people with the disease do not realize they are infected. Large-scale population movements have increased the areas where Chagas disease is found and these include many European countries and the United States. These areas have also seen an increase in the years up to 2014. The disease was first described in 1909 by Carlos Chagas after whom it is named. It affects more than 150 other animals., The members of Triatominae , a subfamily of Reduviidae, are also known as conenose bugs, kissing bugs, assassin bugs, or vampire bugs. Other local names for them used in the Latin Americas include barbeiros, vinchucas, pitos and chinches. Most of the 130 or more species of this subfamily are haematophagous, i.e. feeds on vertebrate blood; a very few species feed on other invertebrates (Sandoval "et al." 2000, 2004). They are mainly found and widespread in the Americas, with a few species present in Asia, Africa, and Australia. These bugs usually share shelter with nesting vertebrates, from which they suck blood. In areas where Chagas disease occurs (from the southern United States to northern Argentina), all triatomine species are potential vectors of the Chagas disease parasite "Trypanosoma cruzi", but only those species (such as "Triatoma infestans" and "Rhodnius prolixus") that are well adapted to living with humans are considered important vectors., Subject: psammolestes, Relation: parent_taxon, Options: (A) area (B) argentina (C) chordata (D) insects (E) protozoa (F) reduviidae (G) rhodnius (H) triatoma (I) triatominae (J) trypanosoma (K) vertebrata

Answer: reduviidae


Question: Context: Immunology is a branch of biology that covers the study of immune systems in all organisms. It was the Russian biologist Ilya Ilyich Mechnikov who boosted studies on immunology, and received the Nobel Prize in 1908 for his work. He jabbed the thorn of a rose on a starfish and noted that, 24 hours later, cells were surrounding the tip. It was an active response of the body, trying to maintain its integrity. It was Mechnikov who first observed the phenomenon of phagocytosis, in which the body defends itself against a foreign body, and coined the term. It charts, measures, and contextualizes the: physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders (such as autoimmune diseases, hypersensitivities, immune deficiency, and transplant rejection); the physical, chemical and physiological characteristics of the components of the immune system "in vitro", "in situ," and "in vivo". Immunology has applications in numerous disciplines of medicine, particularly in the fields of organ transplantation, oncology, virology, bacteriology, parasitology, psychiatry, and dermatology., The Czech Republic, also known by the short name Czechia, is a nation state in Central Europe bordered by Germany to the west, Austria to the south, Slovakia to the east and Poland to the northeast. The Czech Republic covers an area of with mostly temperate continental climate and oceanic climate. It is a unitary parliamentary republic, has 10.5 million inhabitants and the capital and largest city is Prague, with over 1.2 million residents. The Czech Republic includes the historical territories of Bohemia, Moravia, and Czech Silesia., In biology, a species (abbreviated sp., with the plural form species abbreviated spp.) is the basic unit of biological classification and a taxonomic rank. A species is often defined as the largest group of organisms in which two individuals can produce fertile offspring, typically by sexual reproduction. While this definition is often adequate, looked at more closely it is often problematic. For example, in a species complex, the boundaries between closely related species become unclear or disappear altogether. Other ways of defining species include similarity of DNA, morphology, or ecological niche. The presence of locally adaptive traits may further subdivide species into infraspecific taxa such as subspecies., Biology is a natural science concerned with the study of life and living organisms, including their structure, function, growth, evolution, distribution, identification and taxonomy. Modern biology is a vast and eclectic field, composed of many branches and subdisciplines. However, despite the broad scope of biology, there are certain general and unifying concepts within it that govern all study and research, consolidating it into single, coherent field. In general, biology recognizes the cell as the basic unit of life, genes as the basic unit of heredity, and evolution as the engine that propels the synthesis and creation of new species. It is also understood today that all the organisms survive by consuming and transforming energy and by regulating their internal environment to maintain a stable and vital condition known as homeostasis., Evolution is change in the heritable characteristics of biological populations over successive generations. Evolutionary processes give rise to biodiversity at every level of biological organisation, including the levels of species, individual organisms, and molecules., Heredity is the genetic information passing for traits from parents to their offspring, either through asexual reproduction or sexual reproduction. This is the process by which an offspring cell or organism acquires or becomes predisposed to the characteristics of its parent cell or organism. Through heredity, variations exhibited by individuals can accumulate and cause some species to evolve through the natural selection of specific phenotype traits. The study of heredity in biology is called genetics, which includes the field of epigenetics., Genetics is the study of genes, genetic variation, and heredity in living organisms. It is generally considered a field of biology, but intersects frequently with many other life sciences and is strongly linked with the study of information systems., Ribonucleic acid (RNA) is a polymeric molecule essential in various biological roles in coding, decoding, regulation, and expression of genes. RNA and DNA are nucleic acids, and, along with proteins and carbohydrates, constitute the four major macromolecules essential for all known forms of life. Like DNA, RNA is assembled as a chain of nucleotides, but unlike DNA it is more often found in nature as a single-strand folded onto itself, rather than a paired double-strand. Cellular organisms use messenger RNA (mRNA) to convey genetic information (using the letters G, U, A, and C to denote the nitrogenous bases guanine, uracil, adenine, and cytosine) that directs synthesis of specific proteins. Many viruses encode their genetic information using an RNA genome., Metamorphosis is a biological process by which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's body structure through cell growth and differentiation. Some insects, fishes, amphibians, mollusks, crustaceans, cnidarians, echinoderms and tunicates undergo metamorphosis, which is often accompanied by a change of nutrition source or behavior. Animals that goes through metamorphosis are called metamorphoses. Animals can be divided into species that undergo complete metamorphosis ("holometaboly"), incomplete metamorphosis ("hemimetaboly"), or no metamorphosis ("ametaboly")., Homeostasis or homoeostasis is the property of a system in which a variable (for example, the concentration of a substance in solution, or its temperature) is actively regulated to remain very nearly constant. This regulation occurs inside a defined environment (mostly within a living organism's body). Examples of homeostasis include the regulation of the body temperature of an animal, the pH of its extracellular fluids, or the concentrations of sodium (Na) and calcium (Ca) ions or of glucose in the blood plasma, despite changes in the animals environment, or what it has eaten, or what it is doing (for example, resting or exercising). Each of these variables is controlled by a separate homeostat (or regulator), which, together, maintain life. Homeostats are energy-consuming physiological mechanisms., Molecular biology concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, and proteins and their biosynthesis, as well as the regulation of these interactions. Writing in "Nature" in 1961, William Astbury described molecular biology as:, Europe is a continent that comprises the westernmost part of Eurasia. Europe is bordered by the Arctic Ocean to the north, the Atlantic Ocean to the west, and the Mediterranean Sea to the south. To the east and southeast, Europe is generally considered as separated from Asia by the watershed divides of the Ural and Caucasus Mountains, the Ural River, the Caspian and Black Seas, and the waterways of the Turkish Straits. Yet the non-oceanic borders of Europea concept dating back to classical antiquityare arbitrary. The primarily physiographic term "continent" as applied to Europe also incorporates cultural and political elements whose discontinuities are not always reflected by the continent's current overland boundaries., The Max Planck Institute of Molecular Cell Biology and Genetics ( MPI - CBG ) is a biology research institute located in Dresden , Germany . It was founded in 1998 and was fully operational in 2000 . 24 research groups work in molecular biology , cell biology , and developmental biology , supported by various facilities ., Munich (also in British English ) is the capital and largest city of the German state of Bavaria, on the banks of River Isar north of the Bavarian Alps. Munich is the third largest city in Germany, after Berlin and Hamburg, and the 12th biggest city of the European Union, with a population of above 1.5 million. The Munich Metropolitan Region is home to 5.8 million people., Berlin is the capital and the largest city of Germany as well as one of its constituent 16 states. With a population of approximately 3.5 million people, Berlin is the second most populous city proper and the seventh most populous urban area in the European Union. Located in northeastern Germany on the banks of rivers Spree and Havel, it is the centre of the Berlin-Brandenburg Metropolitan Region, which has about 6 million residents from more than 180 nations. Due to its location in the European Plain, Berlin is influenced by a temperate seasonal climate. Around one-third of the city's area is composed of forests, parks, gardens, rivers and lakes., William Thomas Astbury FRS (also Bill Astbury; 25 February 1898, Longton  4 June 1961, Leeds) was an English physicist and molecular biologist who made pioneering X-ray diffraction studies of biological molecules. His work on keratin provided the foundation for Linus Pauling's discovery of the alpha helix. He also studied the structure for DNA in 1937 and made the first step in the elucidation of its structure., Hamburg (local pronunciation ; Low German/Low Saxon: "Hamborg" ), officially "Freie und Hansestadt Hamburg" (Free and Hanseatic City of Hamburg), is the second largest city in Germany and the eighth largest city in the European Union. It is the second smallest German state by area. Its population is over 1.7 million people, and the wider Hamburg Metropolitan Region covers more than 5.1 million inhabitants. The city is situated on the river Elbe., Frankfurt am Main is a metropolis and the largest city in the German state of Hesse and the fifth-largest city in Germany, with a 2015 population of 731,095 within its administrative boundaries, and 2.3 million in its urban area. The city is at the centre of the larger Frankfurt Rhine-Main Metropolitan Region, which has a population of 5.8 million and is Germany's second-largest metropolitan region after Rhine-Ruhr. Since the enlargement of the European Union in 2013, the geographic centre of the EU is about to the east of Frankfurt's CBD, the Bankenviertel. Frankfurt is culturally and ethnically diverse, with around half of the population, and a majority of young people, having a migration background. A quarter of the population are foreign nationals, including many expatriates., Deoxyribonucleic acid (DNA) is a molecule that carries the genetic instructions used in the growth, development, functioning and reproduction of all known living organisms and many viruses. DNA and RNA are nucleic acids; alongside proteins, lipids and complex carbohydrates (polysaccharides), they are one of the four major types of macromolecules that are essential for all known forms of life. Most DNA molecules consist of two biopolymer strands coiled around each other to form a double helix., Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Not all tumors are cancerous; benign tumors do not spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss and a change in bowel movements. While these symptoms may indicate cancer, they may have other causes. Over 100 types of cancers affect humans.
Tobacco use is the cause of about 22% of cancer deaths. Another 10% is due to obesity, poor diet, lack of physical activity and drinking alcohol. Other factors include certain infections, exposure to ionizing radiation and environmental pollutants. In the developing world nearly 20% of cancers are due to infections such as hepatitis B, hepatitis C and human papillomavirus (HPV). These factors act, at least partly, by changing the genes of a cell. Typically many genetic changes are required before cancer develops. Approximately 510% of cancers are due to inherited genetic defects from a person's parents. Cancer can be detected by certain signs and symptoms or screening tests. It is then typically further investigated by medical imaging and confirmed by biopsy.
Many cancers can be prevented by not smoking, maintaining a healthy weight, not drinking too much alcohol, eating plenty of vegetables, fruits and whole grains, vaccination against certain infectious diseases, not eating too much processed and red meat, and avoiding too much sunlight exposure. Early detection through screening is useful for cervical and colorectal cancer. The benefits of screening in breast cancer are controversial. Cancer is often treated with some combination of radiation therapy, surgery, chemotherapy, and targeted therapy. Pain and symptom management are an important part of care. Palliative care is particularly important in people with advanced disease. The chance of survival depends on the type of cancer and extent of disease at the start of treatment. In children under 15 at diagnosis the five-year survival rate in the developed world is on average 80%. For cancer in the United States the average five-year survival rate is 66%.
In 2012 about 14.1 million new cases of cancer occurred globally (not including skin cancer other than melanoma). It caused about 8.2 million deaths or 14.6% of human deaths. The most common types of cancer in males are lung cancer, prostate cancer, colorectal cancer and stomach cancer. In females, the most common types are breast cancer, colorectal cancer, lung cancer and cervical cancer. If skin cancer other than melanoma were included in total new cancers each year it would account for around 40% of cases. In children, acute lymphoblastic leukaemia and brain tumors are most common except in Africa where non-Hodgkin lymphoma occurs more often. In 2012, about 165,000 children under 15 years of age were diagnosed with cancer. The risk of cancer increases significantly with age and many cancers occur more commonly in developed countries. Rates are increasing as more people live to an old age and as lifestyle changes occur in the developing world. The financial costs of cancer were estimated at $1.16 trillion US dollars per year as of 2010.
Definitions.
Cancers are a large family of diseases that involve abnormal cell growth with the potential to invade or spread to other parts of the body. They form a subset of neoplasms. A neoplasm or tumor is a group of cells that have undergone unregulated growth and will often form a mass or lump, but may be distributed diffusely., The European Union (EU) is a political and economic union of member states that are located primarily in Europe. It has an area of , and an estimated population of over 510 million. The EU has developed an internal single market through a standardised system of laws that apply in all member states. EU policies aim to ensure the free movement of people, goods, services, and capital within the internal market, enact legislation in justice and home affairs, and maintain common policies on trade, agriculture, fisheries, and regional development. Within the Schengen Area, passport controls have been abolished. A monetary union was established in 1999 and came into full force in 2002, and is composed of 19 EU member states which use the euro currency., Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of regeneration, asexual reproduction and metamorphosis and in the growth and differentiation of stem cells in the adult organism., In physics, energy is the property that must be transferred to an object in order to perform work on  or to heat  the object, and can be converted in form, but not created or destroyed. The SI unit of energy is the joule, which is the energy transferred to an object by the mechanical work of moving it a distance of 1 metre against a force of 1 newton., Stuttgart ( Swabian: "Schduagert"), often nicknamed the ""Schwabenmetropole"" in reference to its location in the center of Swabia and the local dialect spoken by some natives, is the capital and largest city of the German state of Baden-Württemberg. It is located on the Neckar river in a fertile valley locally known as the "Stuttgarter Kessel" an hour from the Swabian Jura and the Black Forest. Stuttgart's name comes from the Old High German word ""Stuogarten"," or "stud farm"  a reference to the city's founding in 950 AD as a stud farm. Stuttgarts urban area has a population of 623,738, and a further making it the sixth largest city in Germany, 2.7 million people live in the citys administrative region, and another 5.3 million people in its metropolitan area, making it the fourth largest metropolitan area in Germany., A biomolecule or biological molecule is molecule that is present in living organisms, including large macromolecules such as proteins, carbohydrates, lipids, and nucleic acids, as well as small molecules such as primary metabolites, secondary metabolites, and natural products. A more general name for this class of material is biological materials. Biomolecules are usually endogenous but may also be exogenous. For example, pharmaceutical drugs may be natural products or semisynthetic (biopharmaceuticals) or they may be totally synthetic., Leipzig is the largest city in the federal state of Saxony, Germany. With a population of 570,087 inhabitants (1,001,220 residents in the larger urban zone) it is Germany's tenth most populous city. Leipzig is located about southwest of Berlin at the confluence of the White Elster, Pleisse and Parthe rivers at the southern end of the North German Plain., The Free State of Saxony is a landlocked federal state of Germany, bordering the federal states of Brandenburg, Saxony Anhalt, Thuringia, and Bavaria, as well as the countries of Poland (Lower Silesian and Lubusz Voivodeships) and the Czech Republic (Karlovy Vary, Liberec and Ústí nad Labem Regions). Its capital is Dresden, and its largest city is Leipzig., A republic (from ) is a sovereign state, country, or government which is organized with a form of government in which power resides in elected individuals representing the citizen body and government leaders exercise power according to the rule of law. In modern times, the definition of a republic commonly refers to a government which excludes a monarch. Currently, 147 of the world's 206 sovereign states use the word "republic" as part of their official names; not all of these are republics in the sense of having elected governments, nor do all nations with elected governments use the word "republic" in their names., Dresden is the capital city and after Leipzig the second-largest city of the Free State of Saxony in Germany. It is situated in a valley on the River Elbe, near the border with the Czech Republic., A gene is a locus (or region) of DNA which is made up of nucleotides and is the molecular unit of heredity. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. Most biological traits are under the influence of polygenes (many different genes) as well as geneenvironment interactions. Some genetic traits are instantly visible, such as eye colour or number of limbs, and some are not, such as blood type, risk for specific diseases, or the thousands of basic biochemical processes that comprise life., Cell biology (formerly called cytology, from the Greek , "kytos", "vessel") is a branch of biology that studies the different structures and functions of the cell and focuses mainly on the idea of the cell as the basic unit of life. Cell biology explains the structure, organization of the organelles they contain, their physiological properties, metabolic processes, signaling pathways , life cycle, and interactions with their environment. This is done both on a microscopic and molecular level as it encompasses prokaryotic cells and eukaryotic cells. Knowing the components of cells and how cells work is fundamental to all biological sciences; it is also essential for research in bio-medical fields such as cancer, and other diseases. Research in cell biology is closely related to genetics, biochemistry, molecular biology, immunology, and developmental biology., The Elbe (; Low German: "Elv") is one of the major rivers of Central Europe. It rises in the Krkonoše Mountains of the northern Czech Republic before traversing much of Bohemia (Czech Republic), then Germany and flowing into the North Sea at Cuxhaven, northwest of Hamburg. Its total length is ., Natural science is a branch of science concerned with the description, prediction, and understanding of natural phenomena, based on observational and empirical evidence. Mechanisms such as peer review and repeatability of findings are used to try to ensure the validity of scientific advances., In biology, an organism is any contiguous living system, such as an animal, plant, fungus, archaeon, or bacterium. All known types of organisms are capable of some degree of response to stimuli, reproduction, growth and development and homeostasis. An organism consists of one or more cells; when it has one cell it is known as a unicellular organism; and when it has more than one it is known as a multicellular organism. Most unicellular organisms are of microscopic scale and are thus loosely described as microorganisms. Humans are multicellular organisms composed of many trillions of cells grouped into specialized tissues and organs., Cologne is the largest city in the German federal State of North Rhine-Westphalia and the fourth-largest city in Germany (after Berlin, Hamburg, and Munich). It is located within the Rhine-Ruhr metropolitan region, one of the major European metropolitan regions and the largest in Germany, with more than ten million inhabitants., Life is a characteristic distinguishing physical entities having biological processes, such as signaling and self-sustaining processes, from those that do not, either because such functions have ceased, or because they never had such functions and are classified as inanimate. Various forms of life exist, such as plants, animals, fungi, protists, archaea, and bacteria. The criteria can at times be ambiguous and may or may not define viruses, viroids, or potential artificial life as "living". Biology is the primary science concerned with the study of life, although many other sciences are involved., Biochemistry, sometimes called biological chemistry, is the study of chemical processes within and relating to living organisms. By controlling information flow through biochemical signaling and the flow of chemical energy through metabolism, biochemical processes give rise to the complexity of life. Over the last decades of the 20th century, biochemistry has become so successful at explaining living processes that now almost all areas of the life sciences from botany to medicine to genetics are engaged in biochemical research. Today, the main focus of pure biochemistry is on understanding how biological molecules give rise to the processes that occur within living cells, which in turn relates greatly to the study and understanding of tissues, organs, and whole organismsthat is, all of biology., Proteins (or ) are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity., Düsseldorf (Low Franconian, Ripuarian: "Düsseldörp" ) is the capital city of the German state of North Rhine-Westphalia and the seventh most populous city in Germany. Düsseldorf is an international business and financial centre, renowned for its fashion and trade fairs. The city is headquarters to one Fortune Global 500 and two DAX companies. Messe Düsseldorf organises nearly one fifth of premier trade shows., A parliamentary republic is a republic that operates under a parliamentary system of government where the executive branch (the government) derives its legitimacy from and is accountable to the legislature (the parliament). There are a number of variations of parliamentary republics. Most have a clear differentiation between the head of government and the head of state, with the head of government holding real power, much like constitutional monarchies. Some have combined the roles of head of state and head of government, much like presidential systems, but with a dependency upon parliamentary power., The euro (sign: €; code: EUR) is the official currency of the eurozone, which consists of 19 of the member states of the European Union: Austria, Belgium, Cyprus, Estonia, Finland, France, Germany, Greece, Ireland, Italy, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, Portugal, Slovakia, Slovenia, and Spain. The currency is also officially used by the institutions of the European Union and four other European countries, as well as unilaterally by two others, and is consequently used daily by some 337 million Europeans . Outside of Europe, a number of overseas territories of EU members also use the euro as their currency., Germany, officially the Federal Republic of Germany, is a federal parliamentary republic in central-western Europe. It includes 16 constituent states, covers an area of , and has a largely temperate seasonal climate. With about 82 million inhabitants, Germany is the most populous member state of the European Union. After the United States, it is the second most popular immigration destination in the world. Germany's capital and largest metropolis is Berlin. Other major cities include Hamburg, Munich, Cologne, Frankfurt, Stuttgart and Düsseldorf., Subject: max planck institute of molecular cell biology and genetics, Relation: located_in_the_administrative_territorial_entity, Options: (A) africa (B) atlantic ocean (C) austria (D) banks (E) bavaria (F) belgium (G) berlin (H) center (I) central (J) cologne (K) cyprus (L) czech republic (M) dax (N) dresden (O) düsseldorf (P) east (Q) estonia (R) europe (S) european union (T) finland (U) frankfurt (V) free state (W) germany (X) goes (Y) hamburg (Z) hesse ([) italy (\) leeds (]) leipzig (^) liberec (_) munich (`) netherlands (a) newton (b) northwest (c) of (d) portugal (e) prague (f) rhine (g) rise (h) river (i) saxony (j) schengen (k) si (l) slovakia (m) south (n) strand (o) stuttgart (p) thuringia

Answer:
saxony