Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

A study was carried out on 200 patients of ages 20-40 years suffering from acute viral hepatitis. Sera were tested for markers of hepatitis B (HBsAg, and IgM anti-HBc) and hepatitis A (IgM-anti-HAV) by the ELISA technique. Sera negative for the markers of both viruses: Hepatitis A (HAV) and Hepatitis B (HBV) were subsequently tested for IGM Heterophil antibodies against Epstein-Barr virus (EBV) by the Monospot slide test to diagnose acute infectious mononucleosis and tested for anti-CMV (IgM) by ELISA technique for the diagnosis of acute Cytomegalovirus (CMV) infection. Non-A, non-B hepatitis (NANB) was diagnosed by exclusion. The results of the study showed that 133 (66.5%) patients had evidence of HBV infection, while only 9(4.5%) were diagnosed as HAV infection. EBV and CMV were the possible etiological agents of acute viral hepatitis in (3.5%) and 1%) respectively. Accordingly the Non-A, non-B hepatitis in this study amounts to (24.5%) of the acute viral hepatitis.
Which virus can be diagnosed with the monospot test?

In chronic lymphocytic leukemia (CLL) signals from the B cell receptor (BCR) play a major role in disease development and progression. In this light, new therapies that specifically target signaling molecules downstream of the BCR continue to be developed. While first studies on the selective small molecule inhibitor of Bruton's tyrosine kinase (Btk), Ibrutinib (PCI-32765), demonstrated that Btk inhibition sensitizes CLL cells to apoptosis and alters their migratory behavior, these studies however did not address whether Btk-mediated signaling is involved in the process of CLL leukemogenesis. To investigate the requirement of Btk signaling for CLL development, we modulated Btk expression in the IgH.ET CLL mouse model, which is based on sporadic expression of the simian oncovirus SV40 T-antigen in mature B cells. To this end, we crossed IgH.ET mice on a Btk-deficient background or introduced a human Btk transgene (CD19-hBtk). Here we show that Btk deficiency fully abrogates CLL formation in IgH.ET mice, and that leukemias formed in Btk haplo-insufficient mice selectively expressed the wild-type Btk allele on their active X chromosome. Conversely, Btk overexpression accelerated CLL onset, increased mortality, and was associated with selection of non-stereotypical BCRs into CLL clones. Taken together, these data show that Btk expression represents an absolute prerequisite for CLL development and that Btk mediated signaling enhances leukemogenesis in mice. We therefore conclude that in CLL Btk expression levels set the threshold for malignant transformation.
What is the name of Bruton's tyrosine kinase inhibitor that can be used for treatment of chronic lymphocytic leukemia?

The spin-off movie focuses on Matt Stifler (Tad Hilgenbrinck), the younger brother of Steve Stifler from the previous American Pie films. Matt is eager to enter the family business of making porno films, so he can prove to his older brother that he is "up to the standards of the Stifmeister." Stifler and his friends play a prank on the band students during the seniors' graduation ceremony by spraying pepper spray on the mouthpieces of the band's instruments. Matt narrowly escapes getting caught and stows the can of pepper spray in his front pocket, which subsequently leaks onto his genitals. The band members begin to play "Pomp and Circumstance", only to become too irritated by the pepper spray to continue. During the commotion, one of the students trips and pulls down the back curtain, which reveals Matt, who is washing his pepper-spray-soaked genitals in a drinking fountain, in front of the whole school.The band leader Elyse Houston (Arielle Kebbel) demands that Stifler be punished for ruining their performance, stating that he always gets away with his pranks because he is the school's star football player. The school's guidance counselor Chuck Sherman ("The Sherminator") (played by Chris Owen from the original American Pie films) decides that a worthwhile punishment would be for Stifler to attend band camp, in the hopes that he would make friends with the "bandies" and not follow in the footsteps of his much-hated brother.When first arriving, Matt is very disrespectful to the rules and also everyone at Tall Oaks and gets his band group in trouble. He is sent to the office of Noah Levenstein (Jim's father) (Eugene Levy), who works as the camp MACRO (Morale and Conflict Resolution Officer; he's filling in for Michelle as she is now pregnant), recommends that he try to fit in and earn the band's trust, which is the last thing that Matt wants to do. However, a phone call from a friend, who says that earning their trust will get him better footage for his video, inspires Matt to be much more respectful and humble towards the band.Matt finds out that his dorky roommate Ernie Kapolwitz (Jason Earles) has an extensive knowledge of spy cameras and technology, so Matt agrees to let him help with the filming, making his first friend at Tall Oaks. As Matt "is earning the band's trust" he gets into a big confrontation with their rival band leader, Brandon Van der Camp (Matt Barr), and even goes as far as to accept a duel challenge made by him, having no idea what a "duel" is.It turns out that a duel is the two performers showing off their music skills, with Brandon playing the snare drum, and Matt playing the triangle. Throughout the majority of the competition it seems that Brandon is the heavy favourite; during Brandon's second round of performing, Matt walks away humiliated. As Brandon is about to be declared the official winner, Matt comes back playing the bagpipes to the tune of 'Play That Funky Music' showing that he is actually a decent player, surprising everyone, including Elyse, who is pleasantly surprised by Matt's performance.As Matt is still recording the various happenings at the camp, he gradually becomes friends with some of the band members from his school. He gains some respect from Ernie after Matt sets him up on a date with tattooed bandmate Chloe (Crystle Lightning). Matt starts falling for Elyse, who is revealed to have been a friend of Matt's in 8th grade but had a falling out after Matt started hanging around with Steve and his friends and acting like The Stifmeister. Matt is eventually caught with his movies, and his once-friends want nothing more to do with him.After another talk with Jim's Dad, Matt comes to realize that his brother is not as great or cool as he once thought and that following in his footsteps is not a good idea, so he deletes all the videos he recorded at band camp. He even enlists the help of the band to help Elyse get the band scholarship that Stifler

Who is the younger brother of Steve Stifler?