In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Question: In relation to intoxication by anticholinergic agents, point out the correct answer. 
 Options:  <1> In its treatment, atropine is used. <2> The presence of grade III or IV encephalopathy, acute renal failure and severe coagulopathy indicate liver transplantation. <3> Dantrolene is indicated in case of seizures. <4> The basic treatment consists of the repeated administration of activated charcoal and support measures. <5> The decrease in plasma cholinesterase confirms the diagnosis.
4

Question: Which of these statements is NOT a characteristic of phase I clinical trials? 
 Options:  <1> They usually have non-therapeutic goals. <2> They can be done in healthy volunteers. <3> They can be done in patients. <4> They are usually randomized. <5> They are usually open.
4

Question: The cell is destroyed to release the secretion: 
 Options:  <1> Merocrine <2> Apocrine <3> Endocrine <4> Holocrine <5> Paracrine

4