instruction:
In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.
question:
Question: Which of the following characteristics defines an endogenous depression? 
 Options:  <1> Its course is continuous. <2> There is an evening worsening. <3> There is an early awakening. <4> There is a good response to placebo. <5> A neurotic personality intervenes in the etiopathogenesis.
answer:
3


question:
Question: Acetylation of histones affects transcription: 
 Options:  <1> Blocking the incorporation of other components of the transcription machinery. <2> Preventing the remodeling of chromatin. <3> Facilitating the action of helicases. <4> Decreasing sensitivity to nuclear receptors. <5> Reducing the affinity of histones for DNA.
answer:
5


question:
Question: The hepatic synthesis of methionine from homocysteine ​​requires: 
 Options:  <1> Methylmalonyl-CoA mutase. <2> Methylcobalamin. <3> 5'-Adenosilcobalamin. <4> Coenzyme B6. <5> Methionine adenosyl transferase.
answer:

2