instruction:
Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.
question:
Context: Billionaire Boy is a children's fiction book published on 28 October 2010 by HarperCollins and written by David Walliams and illustrated by Tony Ross. 
 Question: Who was Billionaire Boy illustrated by?
answer:
tony ross


question:
Context: A solution is a mixture of two or more substances in which dissolved particles are distributed evenly throughout the solution. The substance that dissolves in a solution is called the solute, and the substance that does the dissolving is called the solvent. The concentration of a solution is the amount of solute in a given amount of solution. A solution with a lot of dissolved solute has a high concentration and is called a concentrated solution. A solution with little dissolved solute has a low concentration and is called a dilute solution. The concentration of a solution represents the percentage of the solution that is the solute. You can calculate the concentration of a solution using this formula: Concentration = Mass (or volume) of Solute Mass (or volume) of Solution 100% For example, if a 100-gram solution of salt water contains 3 grams of salt, then its concentration is: Concentration = 3g 100g 100% = 3% Q: A 1000 mL container of brand A juice drink contains 250 mL of juice and 750 mL of water. A 600 mL container of brand B juice drink contains 200 mL of juice and 400 mL of water. Which brand of juice drink is more concentrated, brand A or brand B? 250 mL 1000 mL 100% = 25% 200 mL 600 mL 100% = 33% A: Concentration(A) = Concentration(B) = You can conclude that brand B is more concentrated. 
 Question: a solution with a small amount of solute for a given amount of solution is called
answer:
dilute.


question:
Context: NADPH oxidase (Nox) family enzymes are one of the main sources of cellular reactive oxygen species (ROS), which have been shown to function as second messenger molecules. To date, seven members of this family have been reported, including Nox1-5 and Duox1 and -2. With the exception of Nox2, the regulation of the Nox enzymes is still poorly understood. Nox1 is highly expressed in the colon, and it requires two cytosolic regulators, NoxO1 and NoxA1, as well as the binding of Rac1 GTPase, for its activity. In this study, we investigate the role of the tyrosine kinase c-Src in the regulation of ROS formation by Nox1. We show that c-Src induces Nox1-mediated ROS generation in the HT29 human colon carcinoma cell line through a Rac-dependent mechanism. Treatment of HT29 cells with the Src inhibitor PP2, expression of a kinase-inactive form of c-Src, and c-Src depletion by small interfering RNA (siRNA) reduce both ROS generation and the levels of active Rac1. This is associated with decreased Src-mediated phosphorylation and activation of the Rac1-guanine nucleotide exchange factor Vav2. Consistent with this, Vav2 siRNA that specifically reduces endogenous Vav2 protein is able to dramatically decrease Nox1-dependent ROS generation and abolish c-Src-induced Nox1 activity. Together, these results establish c-Src as an important regulator of Nox1 activity, and they may provide insight into the mechanisms of tumor formation in colon cancers. 
 Question: Which NADPH oxidase family member requires interaction with NOXO1 for function?
answer:

nadph oxidase 1