In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[EX Q]: Question: In a determination of the activity of an enzyme, the depletion of the substrate: 
 Options:  <1> It is essential for most trials. <2> It may give falsely low results in sera with high enzymatic activity. <3> It occurs when the reagent is finished. <4> It occurs due to a defect in the spectrophotometer. <5> It can lead to falsely elevated results in sera with high enzymatic activity.
[EX A]: 2

[EX Q]: Question: The target of the aminoglycoside antibacterials is the: 
 Options:  <1> DNA polymerase <2> Transpeptidation of peptidoglycan. <3> 30S subunit of the ribosome. <4> RNA polymerase <5> DNA gyrase.
[EX A]: 3

[EX Q]: Question: In collagen, what is the amino acid that is repeated every three residues? 
 Options:  <1> Glycine <2> To the girl. <3> Proline <4> Lysine <5> Hydroxyproline
[EX A]:
1