In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".
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Question: Paragraph: The relative bioavailability of nicotine from a nasal spray was assessed in 15 smokers suffering a common cold and rhinitis according to generally accepted criteria. The patients were given a single dose of 2 mg nicotine from the nasal spray with and without concurrent administration of a nasal vasoconstrictor decongestant, xylometazoline, in randomised order. Control session measurements were made in the disease-free state. Applying strict bioequivalence criteria, we found that common cold/rhinitis slightly reduced the bioavailability of nicotine, both in its rate and extent; the geometric mean of the ratio of Crnax , AUC and tma x were 0.81, 0.93 and 1.36, respectively. The nasal vasoconstrictor, xylometazoline, normalised the extent of the bioavailability of nicotine, but further prolonged the time for absorption to almost twice that measured in the disease-free state, increasing the tma x ratio to 1.72. The results suggest that a minor proportion of people stopping smoking with the help of a nicotine nasal spray may experience a minor reduction in the effect of the spray during common cold/rhinitis. However, the nicotine self-titration behaviour found with most smoking cessation products (except the nicotine patch) will automatically lead to an adjustment of the dosage to achieve the desired effect. 
 Title: Relative bioavailability of nicotine from a nasal spray in infectious rhinitis and after use of a topical decongestant

Answer: False


Question: Paragraph: The nasal epithelium from a young girl was examined by electron microscopy and found to be infected by coronavirus. Virions are seen within and outside the ciliated cells, but not outside or within the goblet cells or other cells of the nasal mucosa. Some virions are located near the microvilli, others in pockets in the apical cell membrane. The cytoplasm contains many small vesicles with a single virion, large apical vesicles containing hundreds of virions, and lysosome-like cytosomes with a moderate number of virions. Some viruslike particles devoid of an electron-dense interior are seen both in the cytosomes and extracellularly. Virus budding was observed in the Golgi apparatus but nowhere else in the cell. The ciliated cells seem not to be destroyed by the viruses, although in many cases the cilia are withdrawn into the cell body. The loss of cilia is likely to cause rhinorrhoea. 
 Title: Ultrastructure of human nasal epithelium during an episode of coronavirus infection

Answer: True


Question: Paragraph: Molecular diagnostic methods are becoming increasingly available for assessment of acute lower respiratory illnesses (ALRi). However, nasopharyngeal/oropharyngeal (np/op) swabs may not accurately reflect etiologic agents from the lower respiratory tract where sputum specimens are considered as a more representative sample. the pathogen yields from np/op against sputum specimens have not been extensively explored, especially in tropical countries. We compared pathogen yields from np/op swabs and sputum specimens from patients ≥18 years hospitalized with ALRI in rural Western Kenya. Specimens were tested for 30 pathogens using TaqMan Array Cards (TAC) and results compared using McNemar's test. The agreement for pathogen detection between NP/OP and sputum specimens ranged between 85-100%. More viruses were detected from np/op specimens whereas Klebsiella pneumoniae and Mycobacterium tuberculosis were more common in sputum specimens. there was no clear advantage in using sputum over np/op specimens to detect pathogens of ALRi in adults using tAc in the context of this tropical setting. Acute lower respiratory illnesses (ALRI) are associated with substantial morbidity and mortality in sub-Saharan Africa 1 . Understanding etiology of respiratory illnesses in resource-limited countries may support clinicians with patient management and provide a framework for decision makers when prioritizing public health interventions. Recently, with availability of multi-pathogen molecular diagnostic methods, and increasing recognition of viruses in cases of ALRI, the use of nasopharyngeal (NP) and oropharyngeal (OP) swab specimens to identify pathogens associated with ALRI has increased 2-4 . However, NP/OP swabs may not accurately reflect etiologic agents from the lower respiratory tract 5 . Sputum specimens, on the other hand, have been considered a more representative sample of the lower respiratory tract 5 , but have not been extensively explored, especially in tropical countries. A multisite study in the United States compared pathogen yield between NP/OP and sputum specimens and argued for the use of high-quality sputum specimens for greater pathogen yield 6 . In contrast, another multisite study in low-middle income countries, observed that the pathogen yield from NP/OP and sputum specimens were similar 2 . Given the paucity of data and the difference in observations in these two recent studies, and that most data from tropical countries were derived from paediatric populations, we aimed to investigate adults living in a tropical, low-income setting. Here we describe the performance of NP/OP swabs against sputum specimens for detecting respiratory pathogens among adult patients hospitalized with ALRI using the TaqMan Array Card (TAC). www.nature.com/scientificreports www.nature.com/scientificreports/ specimen for tuberculosis testing. Moreover, as used by Thea et al. 2 , we considered <10 squamous epithelial cells per low-power field to determine specimen quality and observed that RNP C T values were similar for NP/OP and sputum specimens, giving us confidence that results from sputum specimens were credible. In conclusion, our findings suggest that there is no clear advantage in using sputum specimens over NP/OP swabs to investigate the etiology of ALRI using molecular diagnostics. Interpretation of multi-pathogen molecular laboratory tests, however, needs further investigation, especially in tropical settings where co-detections seem very common. 
 Title: comparison of respiratory pathogen yields from nasopharyngeal/oropharyngeal swabs and sputum specimens collected from hospitalized adults in rural Western Kenya

Answer:
False