Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: Approximately 5-6% of intravaginal clindamycin is absorbed in the bloodstream, making systemic effects possible.

Output: non-adverse drug event


Input: Consider Input: Induction of systemic lupus erythematosus by interferon-gamma in a patient with rheumatoid arthritis.

Output: adverse drug event


Input: Consider Input: A case of allopurinol hypersensitivity, possibly the first in a black African, is reported.


Output: adverse drug event