Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.

[Q]: If true, it would be a profound leap of science and ethics. A U.S. scientist said he took part in the work in China, but this kind of gene editing is banned in the United States because the DNA changes can pass to future generations and it risks harming other genes. Many mainstream scientists think it’s too unsafe to try, and some denounced the Chinese report as human experimentation. The researcher, He Jiankui of Shenzhen, said he altered embryos for seven couples during fertility treatments, with one pregnancy resulting thus far. He said his goal was not to cure or prevent an inherited disease, but to try to bestow a trait that few people naturally have — an ability to resist possible future infection with HIV, the AIDS virus. He said the parents involved declined to be identified or interviewed, and he would not say where they live or where the work was done. There is no independent confirmation of He’s claim, and it has not been published in a journal, where it would be vetted by other experts. He revealed it Monday in Hong Kong to one of the organizers of an international conference on gene editing that is set to begin Tuesday, and earlier in exclusive interviews with The Associated Press. “I feel a strong responsibility that it’s not just to make a first, but also make it an example,” He told the AP. “Society will decide what to do next” in terms of allowing or forbidding such science. Some scientists were astounded to hear of the claim and strongly condemned it. It’s “unconscionable ... an experiment on human beings that is not morally or ethically defensible,” said Dr. Kiran Musunuru, a University of Pennsylvania gene editing expert and editor of a genetics journal. “This is far too premature,” said Dr. Eric Topol, who heads the Scripps Research Translational Institute in California. “We’re dealing with the operating instructions of a human being. It’s a big deal.” However, one famed geneticist, Harvard University’s George Church, defended attempting gene editing for HIV, which he called “a major and growing public health threat.” “I think this is justifiable,” Church said of that goal. In recent years scientists have discovered a relatively easy way to edit genes, the strands of DNA that govern the body. The tool, called CRISPR-cas9, makes it possible to operate on DNA to supply a needed gene or disable one that’s causing problems. It’s only recently been tried in adults to treat deadly diseases, and the changes are confined to that person. Editing sperm, eggs or embryos is different — the changes can be inherited. In the U.S., it’s not allowed except for lab research. China outlaws human cloning but not specifically gene editing. He Jiankui (HEH JEE’-an-qway), who goes by “JK,” studied at Rice and Stanford universities in the U.S. before returning to his homeland to open a lab at Southern University of Science and Technology of China in Shenzhen, where he also has two genetics companies. The university said He’s work “seriously violated academic ethics and standards” and planned to investigate. A spokesman for He confirmed that he has been on leave from teaching since early this year, but he remains on the faculty and has a lab at the school. The U.S. scientist who worked with him on this project after He returned to China was physics and bioengineering professor Michael Deem, who was his adviser at Rice in Houston. Deem also holds what he called “a small stake” in — and is on the scientific advisory boards of — He’s two companies. The Chinese researcher said he practiced editing mice, monkey and human embryos in the lab for several years and has applied for patents on his methods. He said he chose embryo gene editing for HIV because these infections are a big problem in China. He sought to disable a gene called CCR5 that forms a protein doorway that allows HIV, the virus that causes AIDS, to enter a cell. All of the men in the project had HIV and all of the women did not, but the gene editing was not aimed at preventing the small risk of transmission, He said. The fathers had their infections deeply suppressed by standard HIV medicines and there are simple ways to keep them from infecting offspring that do not involve altering genes. Instead, the appeal was to offer couples affected by HIV a chance to have a child that might be protected from a similar fate. He recruited couples through a Beijing-based AIDS advocacy group called Baihualin. Its leader, known by the pseudonym “Bai Hua,” told the AP that it’s not uncommon for people with HIV to lose jobs or have trouble getting medical care if their infections are revealed. Here is how He described the work: The gene editing occurred during IVF, or lab dish fertilization. First, sperm was “washed” to separate it from semen, the fluid where HIV can lurk. A single sperm was placed into a single egg to create an embryo. Then the gene editing tool was added. When the embryos were 3 to 5 days old, a few cells were removed and checked for editing. Couples could choose whether to use edited or unedited embryos for pregnancy attempts. In all, 16 of 22 embryos were edited, and 11 embryos were used in six implant attempts before the twin pregnancy was achieved, He said. Tests suggest that one twin had both copies of the intended gene altered and the other twin had just one altered, with no evidence of harm to other genes, He said. People with one copy of the gene can still get HIV, although some very limited research suggests their health might decline more slowly once they do. Several scientists reviewed materials that He provided to the AP and said tests so far are insufficient to say the editing worked or to rule out harm. They also noted evidence that the editing was incomplete and that at least one twin appears to be a patchwork of cells with various changes. “It’s almost like not editing at all” if only some of certain cells were altered, because HIV infection can still occur, Church said. Church and Musunuru questioned the decision to allow one of the embryos to be used in a pregnancy attempt, because the Chinese researchers said they knew in advance that both copies of the intended gene had not been altered. “In that child, there really was almost nothing to be gained in terms of protection against HIV and yet you’re exposing that child to all the unknown safety risks,” Musunuru said. The use of that embryo suggests that the researchers’ “main emphasis was on testing editing rather than avoiding this disease,” Church said. Even if editing worked perfectly, people without normal CCR5 genes face higher risks of getting certain other viruses, such as West Nile, and of dying from the flu. Since there are many ways to prevent HIV infection and it’s very treatable if it occurs, those other medical risks are a concern, Musunuru said. There also are questions about the way He said he proceeded. He gave official notice of his work long after he said he started it — on Nov. 8, on a Chinese registry of clinical trials. It’s unclear whether participants fully understood the purpose and potential risks and benefits. For example, consent forms called the project an “AIDS vaccine development” program. The Rice scientist, Deem, said he was present in China when potential participants gave their consent and that he “absolutely” thinks they were able to understand the risks. Deem said he worked with He on vaccine research at Rice and considers the gene editing similar to a vaccine. “That might be a layman’s way of describing it,” he said. Both men are physics experts with no experience running human clinical trials. The Chinese scientist, He, said he personally made the goals clear and told participants that embryo gene editing has never been tried before and carries risks. He said he also would provide insurance coverage for any children conceived through the project and plans medical follow-up until the children are 18 and longer if they agree once they’re adults. Further pregnancy attempts are on hold until the safety of this one is analyzed and experts in the field weigh in, but participants were not told in advance that they might not have a chance to try what they signed up for once a “first” was achieved, He acknowledged. Free fertility treatment was part of the deal they were offered. He sought and received approval for his project from Shenzhen Harmonicare Women’s and Children’s Hospital, which is not one of the four hospitals that He said provided embryos for his research or the pregnancy attempts. Some staff at some of the other hospitals were kept in the dark about the nature of the research, which He and Deem said was done to keep some participants’ HIV infection from being disclosed. “We think this is ethical,” said Lin Zhitong, a Harmonicare administrator who heads the ethics panel. Any medical staff who handled samples that might contain HIV were aware, He said. An embryologist in He’s lab, Qin Jinzhou, confirmed to the AP that he did sperm washing and injected the gene editing tool in some of the pregnancy attempts. The study participants are not ethicists, He said, but “are as much authorities on what is correct and what is wrong because it’s their life on the line.” “I believe this is going to help the families and their children,” He said. If it causes unwanted side effects or harm, “I would feel the same pain as they do and it’s going to be my own responsibility.” ___ AP science writer Christina Larson, video journalist Emily Wang and researcher Fu Ting contributed to this report from Beijing and Shenzhen, China. ___ This Associated Press series was produced in partnership with the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.
[A]: Chinese researcher claims first gene-edited babies.


[Q]: Since Nov. 1, South Carolina has recorded 86 reported cases of the contagious disease. State Epidemiologist Linda Bell said Monday that’s more than four times what state officials normally expect to see. Over the last 10 years, South Carolina averaged 19 reported cases of hepatitis A annually. Most of the new cases have occurred in Aiken County, and almost half of all cases involve individuals who reported drug use, Bell said. Still, the general population needn’t be overly concerned, she said. “But we are seeing cases higher that what we expect to see,” Bell said. “And so it’s important for us to do our prevention efforts early to reach those high-risk groups, get them vaccinated ... so that we can prevent” a severe outbreak. The State reports the Department of Health and Environmental Control is offering no-cost vaccines to high risk groups including drug users, homeless, formerly incarcerated and sexually-active gay men. Additionally, health officials recommend all children get two doses of the vaccine as part of their immunization schedule. Of the 86 reported cases in South Carolina, 59 have led to hospitalization and one resulted in death, the DHEC said. Hepatitis is a disease characterized by inflammation of the liver. It comes in many forms, including hepatitis A, B and C. As a result, individuals with chronic liver disease, like cirrhosis, are at increased risk of complications if infected and should be vaccinated. The virus-borne infection can be prevented by vaccination and is usually transmitted person-to-person through consumption of contaminated food or water, according to the U.S. Centers for Disease Control and Prevention. Antibodies produced in response to hepatitis A infection last for life and protect against reinfection. Infection usually results in sickness in two to six weeks after exposure. Symptoms include fatigue, loss of appetite, stomach pain, nausea, and yellowing of the eyes and skin. Symptoms usually resolve within two months of infection, according to the CDC. State public health officials in February declared an outbreak in Aiken County after an employee at a second restaurant in Aiken tested positive for the virus, the DHEC said. Bell, though, stressed transmission by food or beverage is uncommon. “Most transmission in the United States is through person-to-person contact,” Bell said. “Good hygiene - diligently washing your hands - is a good way to prevent hepatitis A, as well as not sharing personal items,” including drug equipment, she said, adding the state has received reports of hepatitis A from people using various drugs, “everything from marijuana to meth.” Residents can schedule an appointment for a vaccination at their local health department by calling 855-472-3432 or going to http://bit.ly/2HhEsM8 . ___ Information from: The State, http://www.thestate.com
[A]: South Carolina declares hepatitis outbreak.


[Q]: No company wants to be the next LM Wind Power. “All it takes is to see something like that happen in a neighboring business or a business similar to yours and everyone gets a lot more fastidious with control measures,” said Dr. Paul Carson, a public health and infectious disease specialist at North Dakota State University, referring to the spread at the Grand Forks plant. Officials with two of the state’s largest plants, window and door maker Marvin and agriculture and construction components producer John Deere Electronic Solutions, say there are new rules of the road. And they’re doing more than the standard protocol of proper hygiene, high-tech protective gear, social distancing and stickers that say, “IF YOU CAN READ THIS YOU ARE TOO CLOSE.” Hallways, entrances, and exits are strictly one-way. Other changes have included temperature checks, unique equipment like “no touch” door openers, liberal leave policies and pay provisions, and an added emphasis on communication between management and workers. ’“The stakes are too high right now,” said Paul Marvin, CEO of Marvin, a century-old Warroad, Minnesota-based company with 6,000 employees in eight states, including 1,300 in the Fargo area. “We want to make people feel comfortable and build trust. It costs you a little money in the short term but it pays dividends in the long run.” The John Deere Electronic Solutions plant in Fargo employs about 750 people. A company spokeswoman said “one of the most impactful steps” they’ve taken is to assure employees that they will be paid if they have symptoms of the virus, don’t feel well or believe they could have been exposed. Marvin employees receive paid leave if they are sick and unpaid leave with health benefits if they just don’t feel comfortable going to work. Paul Marvin said employees don’t have to “prove how sick they are” with notes from their doctors. And their jobs will be waiting for them when they return. North Dakota Gov. Doug Burgum has held up a Canada-based potato processing business as the gold standard for protecting employees from the coronavirus, stating that Cavendish Farms plants in North Dakota and elsewhere have not recorded a single COVID-19 case among thousands of workers. The company employs 250 people at its Jamestown plant. “It has been a family owned-business for decades, taking care of their people,” Burgum said. “They have a culture of safety that has been long established. It’s easy for them to take it up another level.” Cavendish Farms spokeswoman Mary Keith said the numerous safeguards include infrared cameras to monitor the temperatures of people entering buildings and hundreds of signs in multiple languages placed throughout the plants to make employees aware of social distancing and other guidelines. The company purchased 2,700 plexiglass face shields for all of its operations and has added floor-to-ceiling barriers made of plexiglass or wood, she said. “We feel that what we did very well is we reacted early and we reacted fast to the risk and escalated our measures,” Keith said, adding that workers awaiting testing or treatment for COVID-19 receive 10 paid days with health benefits. Meanwhile, the number of infected workers at LM Wind Power stands at about 150 at the Grand Forks plant that employs about 900 people. State and local health officials are undertaking a vigorous contact tracing effort, recruiting dozens of people to help find other COVID-19 cases related to the plant. Some LM employees have complained publicly about what they believed to be a lack of safety precautions, which the company has denied. Officials with the Department of Labor and Human Rights have not received any complaints from LM employees, according to Burgum spokesman Mike Nowatzki. Scott Weislow, Marvin’s director of enterprise risk management, said Marvin had a pandemic blueprint in its library after dealing with the Avian flu and that gave them a head start, he said. “I think we’re going to see an evolution in business; not just us but everybody,” Weislow said. “Working from home will be more acceptable. Some of these social distancing measures are probably going to stick around and you’re going to see other measures like voice activated lights and voice activated door openers.” Carson said when it comes to the coronavirus, even the most stringent measures may not be enough to dodge “the luck of the draw.” It only takes one infected person who’s not showing symptoms to start the spread, he said.
[A]:
Grand Forks outbreak has other North Dakota plants on alert.