Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Input: Consider Input: Context: It is unanimously accepted that there is an unmet need for pain medications that are both effective and safe. Unfortunately, no really novel analgesics have been approved over the past three decades. In view of both experimental and clinical evidence of a major role for nerve growth factor (NGF) in the generation and maintenance of a wide range of pain states, drug discovery efforts focusing on the development of anti-NGF agents have aroused particular interest. Several humanized anti-NGF monoclonal antibodies (mAbs) have entered clinical trials as potential analgesics. In this respect, tanezumab is at an advanced stage of clinical development while fulranumab, fasinumab and ABT-110, previously known as PG110, are in early phases of clinical development. This Current Opinion article aims at describing the rationale for targeting NGF for pain, reviewing the analgesic efficacy and safety of anti-NGF agents based on data from fully published studies, conference abstracts, and the US Food and Drug Administration (FDA) website, and discussing the possible future of these agents in managing chronic pain. Anti-NGF mAbs produced significant pain relief and functional improvement in patients with osteoarthritis of the knee and/or hip. Conversely, studies in non-specific lower back pain generated mixed results; overall, this condition appeared to be less responsive to anti-NGF agents than osteoarthritis. Finally, there was no conclusive evidence of the effectiveness of anti-NGF mAbs in some types of chronic visceral or neuropathic pain. Furthermore, these studies raised safety concerns about anti-NGF mAbs. As a class, these drugs may cause or worsen peripheral neuropathies. But the most problematic issue-which prompted the FDA to place studies of these compounds on clinical hold in 2010-was rapid joint destruction leading to joint replacement surgery. The aetiologies of these side effects have been much debated and their pathophysiology is poorly understood. After an Arthritis Advisory Committee meeting held in March 2012, pharmaceutical companies negotiated with the FDA on the conditions for restarting clinical studies. Although the FDA lifted its clinical hold, there remain many unresolved issues about the long-term efficacy and safety of anti-NGF mAbs. While acknowledging that the future of these drugs is unforeseeable, it appears that they may not be the safe and effective painkillers that have been awaited for decades. 
 Question: What is the target of tanezumab?

Output: ngf


Input: Consider Input: Context: You're in your office when you learn there's someone with a gun wandering outside. You can hear gunshots and screams. What do you do? That's the challenge for users of a new virtual reality program called SurviVR, designed to train employees how to deal with an active shooter situation in the workplace. The program works with HTC Vive, the virtual reality headset released earlier this year. An active shooter situation is when an armed person or people actively shoot in a small, populated area with the intention to kill. There were 20 such situations in the United States last year and 20 the year before, according to FBI statistics, resulting in a total of 231 deaths. This year saw the deadliest active shooter situation in US history , with 49 people killed in a nightclub in Orlando. In the training situation, users have four choices. They can lock themselves in the office. They can hide, perhaps in the office closet. They can run for an exit. Or they can use something in the office--a computer or a cup a pair of scissors-as a weapon to fight the shooter. This is an improvement on standard active shooter training. Gallo says, which typically teachers people to lock themselves in place and hide. The "lock down" method is often ineffective, he says, and has resulted in many deaths in recent years. In the training's basic level, no one gets killed. But as the trainings become more advanced, players who make a wrong choice be shot. There's no blood; the screen simply turns black slowly. If this sounds terrifying, that's the point, says Gallo. There are plenty of training programs to teach employees how to deal with workplace violence, sometimes involving role play with toy guns. But these trainings are basically games. Gallo says, with employees relaxed and even enjoying themselves. To teach people what they really need to know for an active shooter situation, they need to be scared. "SurviVR will take the fear and turn it into confidence." Gallo says. 
 Question: What does Gallo think of the training programs involving role play with toy guns?

Output: ineffective


Input: Consider Input: Context: Rene-Marie Ehuzu (April 12, 1944 -- October 17, 2012) was the Roman Catholic bishop of the Roman Catholic Diocese of Porto Novo, Benin. 
 Question: Which was the position that Rene-Marie Ehuzu held?


Output: bishop