Translate the given Spanish text to English

Ex Input:
The present disclosure generally relates to crystalline forms of N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R</ )-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N-((1R,2S )-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-proli namide.

Ex Output:
La presente invención se refiere de forma general a formas cristalinas de N-(terc-butoxicarbonil)-3-metil-L-valil-(4R)-4-((7- cloro-4-metoxi-1-isoquinolinil)oxi)-N-((1R,2S)-1-((ciclopropilsul fonil)carbamoil)-2-vinilciclopropil)-L-prolinamida.


Ex Input:
The present invention also encompasses the resulting stabilized nitrile.

Ex Output:
La presente invencion también abarca el nitrilo estabilizado resultante.


Ex Input:
In particular, the compounds show potent antiviral activity against HIV-1, HIV-2, HCV, Norovirus, Saporovirus, cytomegalovirus (CMV), herpes viruses (HSV-1, HSV-2), Dengue virus, Yellow fever, and HBV.

Ex Output:

En particular, los compuestos muestran una potente actividad antiviral contra VIH-1, VIH-2, HCV, Norovirus, Saporovirus, citomegalovirus (CMV), virus herpes (HSV-1, HSV-2), virus Dengue, fiebre Amarilla, y HBV.