instruction:
Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
question:
Question: Does peroxiredoxin II negatively regulate lipopolysaccharide-induced osteoclast formation and bone loss via JNK and STAT3?
Answer: We suggest that PrxII could be useful in the development of a novel target for inflammatory bone loss.
answer:
yes


question:
Question: Is prooxidant-anti-oxidant balance associated with extent of coronary artery disease?
Answer: In conclusion, we found higher levels of oxidative stress in CAD+ patients compared to healthy subjects. The oxidation level was not related to measures of the extent of CAD such as number of stenosed vessels.
answer:
no


question:
Question: Does notch signaling enhance osteogenic differentiation while inhibiting adipogenesis in primary human bone marrow stromal cells?
Answer: In summary, our data suggest that induction of Notch signaling enhances the osteogenic differentiation of hBMSCs while inhibiting the adipogenic fate.
answer:

yes