TASK DEFINITION: Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
PROBLEM: Severe autoimmune hemolytic anemia following rituximab therapy in a patient with a lymphoproliferative disorder.

SOLUTION: adverse drug event

PROBLEM: This case and a review of the literature show the severe and unpredictable nature of ethambutol toxicity and its potential for irreversible vision loss despite careful ophthalmologic monitoring.

SOLUTION: adverse drug event

PROBLEM: Aromatic antiepileptic agents, such as phenytoin, carbamazepine, and phenobarbital are the most frequent causes of this syndrome.

SOLUTION:
non-adverse drug event