Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Example Input: Her case was complicated by social and behavioral issues.
Example Output: non-adverse drug event

Example Input: Chronic hydroxychloroquine use associated with QT prolongation and refractory ventricular arrhythmia.
Example Output: adverse drug event

Example Input: Transrectal ultrasound-guided needle biopsy of the prostate is a widely accepted technique to obtain prostatic tissue for histological examination.
Example Output:
non-adverse drug event