Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Q: It is a potentially serious reaction which is little influenced by which drug is injected.

A: non-adverse drug event
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Q: 2-CdA induces lymphocytopenia, which may explain the improvement in this patient's psoriasis.

A: adverse drug event
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Q: We report on three patients who developed acute liver damage during therapy with itraconazole, and in whom liver biopsy specimens were obtained.

A:
adverse drug event
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