Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Ex Input:
Paragraph: A panel of Food and Drug Administration advisers voted unanimously in favor of Amgen’s version of AbbVie’s Humira, a biotech drug that raked in nearly $15 billion last year, according to IMS Health. While not binding, the recommendation likely paves the way for FDA approval of the knockoff drug. For years, biotech drugs faced no competition because there was no regulatory way to approve copycat versions, even after patents had expired. If approved, Amgen’s drug would join a new wave of so-called biosimilars, which have the potential to generate billions in savings for U.S. insurers, doctors and patients. But it could take years for those savings to arrive. Evercore ISI analyst Mark Schoenebaum says the earliest Amgen could launch its product would be March 2017, though that would risk infringing patents which Abbvie says protect its drug until at least 2022. Wall Street analysts expect the patent issue to be fought in court, and then for Amgen’s drug to launch sometime between 2018 and 2022. First approved in 2002, Humira has long been among the most profitable drugs in the world. It accounted for 60 percent of Abbvie’s total revenue last year. The injectable drug, which blocks chemicals linked to inflammation, is approved for multiple uses, including rheumatoid arthritis, Crohn’s disease and psoriasis. Thousand Oaks, Calif-based Amgen is seeking FDA approval to market its version, known only as ABP 501, for seven diseases. Amgen is itself a biotech powerhouse, and it too has medications facing competition from cheaper versions. The company is working to hedge those loses by developing lower-cost versions of competitors’ drugs. Biotech drugs are powerful, injected medicines produced in living cells that are typically much more expensive than traditional, chemical-based drugs. In 2015, six of the 10 top-selling medicines globally were biotech drugs, with more than $56 billion in combined sales. The FDA only approved the first lower-cost biotech drug last March, a Novartis version of the Amgen drug Neupogen. Pfizer won approval to market a second biosimilar in April, a version of Johnson & Johnson’s Remicade, but it is not yet for sale. Questions remain about just how much savings U.S. biosimilars will deliver. Novartis’ Zarxio sells for 15 percent less than the original Neupogen. Experts predict biosimilar discounts of 15 percent to 30 percent in the U.S. In Europe, where governments regulate prices, discounts are higher. Development of lower-cost anti-inflammatory drugs like Humira is considered pivotal in reducing U.S. spending on specialty drugs, which has doubled to $150 billion since 2010, according to IMS Health. On Wednesday, the same panel of FDA advisers will review a Novartis version of Enbrel, which is marketed by Amgen. Claim: Lower-cost biotech drug gets thumbs up from FDA panel.

Ex Output:
The second-biggest selling drug in the world could get some cheaper competition in the U.S., after a federal panel endorsed an alternative version of the pricey medication used to treat rheumatoid arthritis and other inflammatory diseases.


Ex Input:
Paragraph: KOMO-TV reports the outbreak was investigated by Public Health Seattle-King County after at least 30 people reported becoming ill after consuming food and drinks at the tavern on November 23 and 24. During the investigation, inspectors identified at least 11 employees who experienced norovirus symptoms since Nov. 24. At least two of those employees had household members with symptoms dating back to Nov. 20, health officials said Wednesday. In response to those findings, Brave Horse Tavern closed down on Nov. 27 and carried out a thorough cleaning and disinfection. All ready-to-eat foods were discarded as well, and the restaurant reopened on Nov. 29. Claim: Dozens sickened by outbreak of norovirus-like illness.

Ex Output:
Health officials say at least 43 people have been sickened by an outbreak of norovirus-like illness - including vomiting, diarrhea, body aches, chills, and fever - linked to Brave Horse Tavern in Seattle.


Ex Input:
Paragraph: On low-fat diets, fruit and oatmeal are fine. With the latest diet trend, no foods at all are allowed for long stretches of time. A diet that forbids eating for hours on end might seem doomed in a culture where food is constantly available, but apps and Facebook groups are popping up for people practicing “intermittent fasting.” Bri Wyatt, a 32-year-old Tennessee resident, tried it this summer. “At first I was like, there’s no way,” she said. But after reading more about it, she thought it might not be that hard. She started by skipping breakfast and night-time snacks, and later moved on to a 60-day challenge of fasting every other day. Melissa Breaux Bankston, a Crossfit instructor in New Orleans, Louisiana, also tried intermittent fasting as a way to curb her snacking. “I wanted to limit the amount of time that I was eating,” she said. Studies on the potential health benefits of intermittent fasting are still limited, including for its effectiveness with weight loss. But heading into the new year, you may be wondering whether it could help you get in better shape. WHEN, NOT WHAT Like other diets, intermittent fasting helps you lose weight by setting boundaries around food. But instead of limiting what you eat, it restricts when you eat. “It’s really another way of fooling your body into eating less calories,” said Krista Varady, who studies intermittent fasting at the University of Illinois at Chicago. Proponents say intermittent fasting helps with weight loss in other ways. For instance, they say it forces your body to start burning its own fat for fuel after depleting the energy it normally gets from food. But any effects would depend on the specific approach you take, and Varady said there isn’t strong evidence yet that intermittent fasting has any unique effects compared with other diets. Regardless, people should consult their doctor before trying it. It’s not advised for children, people on certain medications and people with a history of eating disorders. FASTING MENU One of the more popular approaches to intermittent fasting is to limit eating to an 8-hour window and to fast during the day’s other 16 hours. This is called time-restricted feeding and isn’t as difficult as some other approaches, since the fasting period can include the time you’re asleep. Many people tailor the eating window to be shorter or longer. Some eat just one meal a day, while others fast entire days a couple times a week. On fasting days, people may allow themselves around 600 calories if needed. But Dr. Jason Fung, who has written books on intermittent fasting, says skipping food altogether might actually be easier, since eating small amounts could stimulate appetite. Whatever the method, people aren’t supposed to gorge when they stop fasting. Fung says it’s a myth that fasting leaves you famished. Sumaya Kazi, who posts about her intermittent fasting online and offers coaching services on the diet, says it seems more difficult than it is partly because overeating has become the norm. “Intermittent fasting is more of a mental challenge than a physical challenge,” she says. But people react differently to diets, and fasting may be a lot harder for some than for others, says Dr. Fatima Stanford, a Harvard Medical School obesity specialist. “There’s no one size fits all,” she said. FASTING ON TRIAL Obesity experts have become interested in intermittent fasting, but studies on the diet are still emerging. For now, limited research suggests it may not be any better for weight loss than conventional calorie-cutting over the long term. “Unfortunately, intermittent fasting gets a little hyped,” said Courtney Peterson, who studies the diet at the University of Alabama at Birmingham. Still, some fasting approaches may be more effective than others. And Peterson notes the difficulty of designing studies that definitively capture a diet’s effects. That’s in part because so many other variables could be at play. For instance, researchers are looking at whether any benefits of intermittent fasting might be tied to when the eating period falls and fluctuations in how well our bodies process food throughout the day. Some health experts say intermittent fasting might be too difficult for many people. They point to a study of 100 people where those placed in the alternate-day fasting group lost around the same amount of weight as those on conventional calorie-restriction diets over time. But the fasting group had a dropout rate of 38%, compared with 29% for the conventional diet group. But intermittent fasting may be easier than other diets for people who already skip meals when they’re too busy, said Varady of the University of Illinois at Chicago. To make weight loss stick, she said people should pick diets that resemble how they already eat. “Different diets do work for different people,” she said. ___  The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content. Claim: In a 24/7 food culture, periodic fasting gains followers.

Ex Output:

On low-carb diets, meat and cheese are OK.