Given scientific fact as input, generate the question from this fact such that it can be answered from the input.

Example Input: Pleiotropic effects causes symptoms associated with sickle-cell disease.
Example Output: What causes symptoms associated with sickle-cell disease?

Example Input: In the lungs, oxygen diffuses out of the alveoli and into capillaries.
Example Output: In the lungs, oxygen diffuses out of the alveoli and into where?

Example Input: Anaerobic type of organism was the only able to live in the anoxic atmosphere of the first 2 billion years.
Example Output:
What type of organism was the only able to live in the anoxic atmosphere of the first 2 billion years?