Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[Q]: The dodo is among the most famous extinct creatures, and _ for human-caused extinction events. Despite its bad name, and the fact that the species was alive during recorded human history, little is actually known about how this animal lived, looked, and behaved. A new study of the only known complete skeleton from a single bird takes advantage of modern 3-D laser scanning technology to open a new window into the life of this famous extinct bird. The study was presented at the 74th Annual Meeting of the Society of Vertebrate Paleontology in Estrel, Berlin. Leon Claessens, Associate Professor at the College of the Holy Cross, and lead researcher on the study said that, "the 3-D laser surface scans we made of the fragile dodo skeletons enable us to reconstruct how the dodo walked, moved and lived to a level of detail that has never been possible before. There are so many outstanding questions about the dodo bird that we can answer with this new knowledge." A complete dodo skeleton, found by an amateur collector and barber, Etienne Thirioux, on the island of Mauritius between 1899 and 1917, has remained unstudied, even though it is the only complete dodo skeleton from a single individual bird known to exist. All other skeletons are incomplete combinations, meaning that they are gathered from more than one individual. In addition, Thirioux constructed a second, partially combined skeleton, which contains many bones that also belong to a single bird. "Being able to examine the skeleton of a single, individual dodo, which is not made up from as many individual birds as there are bones, as is the case in all those other combined skeletons, truly allows us to appreciate the way the dodo looked and see how tall or fat it really was," said Juilan Hume, of the Natural History Museum UK, a co-author on the study. The scans were performed on site in Durban, South Africa, and allow examination of the biology of this mysterious extinct bird in detail for the first time. Using the newest digital tools and techniques, the scans provide an insight into how the flightless dodo may have developed its giant size, and how it walked and lived in its forest home. According to Kenneth Rijsdijk, a biologist from University of Amsterdam, "the skull of the dodo is so large and its mouth so strong that it is easy to understand that the earliest naturalists thought it was related to sharks and other birds of prey , rather than the pigeon family."
[A]: What is special about the dodo skeleton found by an amateur collector?


[Q]: In yeast, the macromolecular complex Set1/COMPASS is capable of methylating H3K4, a posttranslational modification associated with actively transcribed genes. There is only one Set1 in yeast; yet in mammalian cells there are multiple H3K4 methylases, including Set1A/B, forming human COMPASS complexes, and MLL1-4, forming human COMPASS-like complexes. We have shown that Wdr82, which associates with chromatin in a histone H2B ubiquitination-dependent manner, is a specific component of Set1 complexes but not that of MLL1-4 complexes. RNA interference-mediated knockdown of Wdr82 results in a reduction in the H3K4 trimethylation levels, although these cells still possess active MLL complexes. Comprehensive in vitro enzymatic studies with Set1 and MLL complexes demonstrated that the Set1 complex is a more robust H3K4 trimethylase in vitro than the MLL complexes. Given our in vivo and in vitro observations, it appears that the human Set1 complex plays a more widespread role in H3K4 trimethylation than do the MLL complexes in mammalian cells.
[A]: Which is the histone residue methylated by MLL1?


[Q]: Isias was the daughter of King Ariobarzanes I of Cappadocia and his wife Queen Athenais Philostorgos I, while her brother was King Ariobarzanes II of Cappadocia.
[A]:
Who was the brother of Isias?