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A few years ago he began working with Dr. Jenny Chang  medical director of the Lester and Sue Smith Breast Center at Baylor College of Medicine.
 Chang had performed a number of biopsies on breast cancer patients  both on those whose cancers were confined to the breast and on those whose cancers had metastasized to the brain.
 From those biopsies  Chang said she had identified a number of genetic pathways ways in which gene mutations affected the ability of the cancer to spread unique to patients who developed metastatic breast cancer.
 "But I had a lot of trouble with the data and trying to translate it into clinical practice " she said. She couldn't find her way out from beneath the avalanche of data.
 So she turned to Wong.
 Using his mathematical modeling  Wong sifted through Chang's data and the large databases of genome and clinical trial data. Out of that  he identified several candidate drugs to impair the genetic pathways that helped the cancer spread.
Chang's data and the large databases of genome and clinical trial data. Out of that  he identified several candidate drugs to impair the genetic pathways that helped the cancer spread.
 One of them  a drug named sunitinib  which treats a kidney cancer called renal cell carcinoma  emerged as the best bet. Chang then tested the drug in mice  and the study showed it prevented breast cancer from spreading to the brain.
 She has already begun a Phase II clinical trial of the drug  enrolling nine patients with metastatic breast cancer  and she is looking for more.
 "The drug is very well-tolerated by patients  and so far the trial is going very well " Chang said.
 But by using an existing drug  Chang and Wong could skip the lengthy Phase I  during which a drug is checked for safety. If Chang's tests go well  sunitinib could be on the market within a few years for metastatic breast cancer.
IN OLD DRUGS RESEARCHER LOOKS FOR NEW TREATMENTS

PRAGUE (Reuters) - Czechs voted on Friday in an election expected to hand power to businessman Andrej Babis who has won popular support by pledging to sweep aside traditional parties  boost investment and keep out refugees  but faces a criminal probe for suspected fraud.
“We want to form a government and show people that government can work differently to what they are used to. We would be (more) in touch with them ”  Babis  said after voting in the Prague suburb where  he  lives.
 Babis ’s support has weathered investigation into tax strategies at  his  empire of food  chemicals  farming and media -- worth an estimated $4 billion -- that  he  owned until moving it to a trust fund this year.
 He  has also been charged by police with fraud on suspicion that  he  hid ownership of a farm and a conference center so it could receive a 2 million euro subsidy in 2008.  He  denies any wrongdoing.
Czechs vote for new parliament wealthy businessman seen as likely next PM

"LeBron James demands that everybody bow down to him . 
With ESPN 's Stephen A. Smith dropping the gossip bomb of the summer Tuesday alleging that LeBron James wants to ` beat Kyrie Irving 's ass ' for Irving 's public desires to abandon Cleveland to rid himself of LBJ 's overbearing reign , Clay Travis mocked ` The King ' for once again turning the docile NBA offseason into an episode of ` Monday Night Raw ' . 
"LeBron James is insulted because he believes he is the Alpha Dog and he wants everybody else on that team to acknowledge that they are a beta and that they 're willing to do whatever LeBron James says ," Travis said . 
"If you are LeBron James and you are threatening to beat somebody up at the age of 33 , you 're a loser and a bully ," he said . 
LeBron James has rabbit ears and this is perfect evidence of it ."

LeBron James is a Bully .