Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

[Q]: Question: Does implementing goal-directed protocols reduce length of stay after cardiac surgery?
Answer: A milestone-driven pathway supported by team rounding was associated with decreased lengths of CVICU and hospital stay. However, tracking patient trajectories by milestones suggests a more complex relationship than anticipated and presents new opportunities for SREBP implementation and research.
[A]: yes


[Q]: Question: Is hIC2 a novel dosage-dependent regulator of cardiac development located within the distal 22q11 deletion syndrome region?
Answer: Our results demonstrate a novel role for Hic2 in cardiac development. Hic2 is the first gene within the distal 22q11 interval to have a demonstrated haploinsufficient cardiac phenotype in mice. Together our data suggest that HIC2 haploinsufficiency likely contributes to the cardiac defects seen in distal 22q11 deletion syndrome.
[A]: yes


[Q]: Question: Does the pre-operative rate of growth of colorectal metastases in patients selected for liver resection influence post-operative disease-free survival?
Answer: The rate of growth of colorectal liver metastases prior to surgery should not be used as a prognostic factor when considering the role of resection.
[A]:
no