In this task, you are given a sentence. You are expected to recognize the name of gene or protein. Although there might be several correct answers, you need to write one of them.
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Question:  Previous studies indicated that aspirin ( acetylsalicylic acid [ ASA ] ) can have profound immunomodulatory effects by regulating cytokine gene expression in several types of cells .

Answer: cytokine gene


Question:  Terminally differentiated skin mast cells also failed to up - modulate their ICAM - 3 , suggesting the requirement for some degree of immaturity for the process .

Answer: ICAM - 3


Question:  The functional importance of the other binding sites only became apparent when combinations of mutations were analyzed .

Answer:
binding sites