Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Q: Paragraph: The analysis suggests the potentially harmful effect of Celebrex dosage is most pronounced in higher-risk patients, researchers said at the American College of Cardiology scientific meeting. “Patients at low cardiovascular risk should take some level of comfort,” said Dr. Scott Solomon, lead researcher of the National Cancer Institute-sponsored analysis. “That wasn’t so clear previously.”   Doctors should exercise caution in prescribing the drug, generally known as celecoxib, in high-risk patients, said Solomon, whose analysis was also published online in the journal Circulation. Celebrex belongs to a class of pain drugs known as cox-2 inhibitors and is the only such drug still on the market in the United States. Merck and Co Inc withdrew its widely used cox-2 drug, Vioxx, from the market in 2004 after a study showed it doubled the risk of heart attack and stroke in long- term users. Another cox-2 inhibitor from Pfizer called Bextra was also pulled from the U.S. market due to safety concerns. While the analysis sheds light on how the drug should be used, Solomon said he could not judge whether the data lift the cloud over this class of drugs. The six trials involving a total of 7,950 patients all studied Celebrex against a placebo for uses other than arthritis. Patients received either 400 milligrams once a day, 200 mg twice a day, or 400 mg twice a day. The primary goal of the pooled analysis was an assessment of the combined risk of cardiovascular death, heart attack, stroke, heart failure or events involving blood clots. Researchers found the heart risk was lowest at the 400 mg daily dose. They found nearly a two-fold risk of adverse heart events with the 200 mg twice daily dose and that jumped to about a three-fold risk at the 400 mg twice daily dose. “Even 400 mg once a day showed elevated risk” in the high-risk population, Solomon said, adding he could not extrapolate whether doses lower than 400 mg cut risk further. The increased risk was not affected by aspirin use, researchers said. “Most of the data used in this pooled analysis have previously been published and are consistent with what we already know about the cardiovascular risks of Celebrex and other prescription arthritis pain relievers,” said Gail Cawkwell, Pfizer’s executive medical director. “The analysis doesn’t provide any new conclusions on the FDA-approved doses of Celebrex, including the most commonly prescribed dose of 200 mg daily,” she said. Dr. Steven Nissen of the Cleveland Clinic, who has a study on lower doses underway, added: “There aren’t long-term randomized placebo-controlled trials for that dose, The only way we’re ever going to answer these questions is with good randomized prospective data,” he said. “We’ll tell it like it is when the data is in.” Claim: Celebrex risky in high-risk patients, study finds.

A: Doctors should prescribe the lowest doses of Celebrex possible in patients at high risk of heart problems, researchers who did a combined analysis of six studies of the Pfizer Inc pain drug said on Monday.
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Q: Paragraph: "South Florida has a reputation as a place ripe for fraud and crime -- including bilking the government. State Rep. Ron Saunders, the Democratic minority leader from Key West, has slapped a more specific label on a costly problem in South Florida: Medicaid fraud. ""The two worst counties for fraud in the country -- not state -- are Dade and Broward county,"" he told a roomful of reporters on Jan. 19, 2011, during an Associated Press preview of Florida's upcoming legislative session. It's easy to find news articles describing South Florida as a mecca for such fraud -- with labels such as ""ground zero"" or mind-boggling tales of abuse. But the word ""worst"" caught our eye -- are the South Florida counties of Miami-Dade and Broward truly the ""worst"" in the country for Medicaid fraud? Medicaid, a health care program for low-income individuals, is administered by the states and receives some federal funding. The Truth-O-Meter has weighed in multiple times on fact-checks related to the high cost and growth of Medicaid, including a claim by Pam Bondi, now Florida's attorney general, and Bill McCollum, Florida's previous attorney general. For more background, check out this website of the federal Centers for Medicare and Medicaid Services. We spoke to Saunders directly on Jan. 20, who told us that his statement was in response to a question about how to resolve the state's budget crisis. Saunders said it's a ""no-brainer"" to cut back on fraud such as in Medicare and Medicaid rather than make more cuts in areas such as education. But after a lot of calls and research, we can say one thing for certain: Nobody tracks county-by-county Medicaid fraud nationally. Even within Florida, a county breakdown is not available. So we're going to rely on expert opinions and documented trends in this ruling. Mark Hollis, spokesperson for the House Democratic caucus, sent us links to newspaper articles and government reports about Medicaid fraud in South Florida. Among the sources Hollis cited was a March 2009 article in Health News Florida, quoting state Sen. Don Gaetz saying: ""Since we have the worst problem in the nation, we need the most effective solution."" Hollis also sent us a December 2005 article in HomeCare, an industry publication, quoting FBI agent Michael Clemens, who was in charge of the Miami field office at the time, saying: ""South Florida is ground zero for health care fraud."" But neither article provides any documentation to support that ""worst"" label. Hollis also sent us links to a House bill and recent government reports about Medicaid fraud. House Bill 1487 in 2009, which labeled Miami-Dade an area of ""special concern,"" was intended to rein in Medicaid fraud. The Senate version, Senate Bill 2658, was signed into law in June 2009. The staff analysis outlined the rampant growth in home health care agencies in Florida: Of the 431 licensure applications in 2007, 58.5 percent were in Miami-Dade. In that county, the number of licensed agencies grew 414 percent between August 1999 and March 6, 2009. The analysis also stated that ""While Miami-Dade has about 20 percent of Florida’s Medicaid population and about 33 percent of Florida’s residents over the age of 60, 91 percent of the state reimbursement for certain home health services were going to Miami-Dade."" While the bill analysis doesn't provide data ranking all of Florida's counties, it certainly suggests that Miami-Dade has an overwhelmingly disproportionate share of Medicaid dollars -- and fraud. Florida's Agency for Health Care Administration, which administers the Medicaid program, has a report from 2009-10 that also provides some insight. Although the 94-page report does not describe Broward and Miami-Dade as the worst in the nation, it noted:  • ""Home health agencies have been an acknowledged area of health care fraud in recent years. For the four fiscal years ending June 30, 2009, approximately 90 percent of Medicaid expenditures for home health aide visits were made to providers in Miami‐Dade County, while only about 20 percent of Medicaid recipients reside in that area. At the end of the fiscal year, there were 339 home health agencies in Miami‐Dade County actively enrolled in the Medicaid program and only 293 in the other 66 counties combined."" (Page 53)  • Statutes were changed in 2008 and 2009 to address home-health fraud. Forty-seven licensure denials for home health agencies were upheld in FY 2009-10 for fraud-related reasons. Thirty-one of the denials (66 percent) were in Miami-Dade County. (Page 65)  We reached out to several agencies that have a role in Medicaid. Both the Florida Attorney General, which has a Medicaid Fraud Control Unit, and AHCA said they had no nationwide county-by-county information to support or refute Saunders' claim. Don White, spokesman for the Office of Inspector General for the U.S. Department of Health and Human Services, also told us that the federal government has ""no statistics on Medicaid fraud."" As for Saunders' claim that Dade and Broward are the ""worst"" in the country, White said: ""Do we have the numbers? No. Is he probably correct? Yes."" We ran Saunders' claim by Alan Levine, a former secretary at AHCA under Gov. Jeb Bush and an expert on Medicaid. ""I have absolutely no doubt South Florida is among the highest,"" Levine wrote in an e-mail. ""Others that likely run in the same circle are New York and New Jersey. But South Florida, from all the experience I have, clearly leads the way."" Levine sent us a 2009 report, ""Stop Paying the Crooks,"" by the Center for Health Transformation, an organization founded by former House Speaker Newt Gingrich. It stated that the U.S. Department of Justice labeled ""South Florida -- and more specifically, Miami-Dade County --Ground Zero for health care fraud in America."" But no numbers ranking counties nationwide. We sent Saunders' claim to Craig Smith, the attorney who wrote the South Florida chapter, who works at Hogan Lovells law firm in Miami. ""Whatever the exact figure is, there can be no question that the bulk of the fraud, waste and abuse is occurring in Miami-Dade and Broward counties,"" Smith wrote to us in an e-mail Feb. 1. ""Based on the size of Florida's Medicaid program, you can fairly eliminate about 45 states from the comparative discussion."" So let's review: Saunders said that ""The two worst counties for (Medicaid) fraud in the country -- not state -- are Dade and Broward county."" We could not find any government office that could point to numbers ranking counties across the nation in terms of Medicaid fraud. But we found four experts -- one from the federal Department of Health and Human Services Office of Inspector General, one a former secretary of the state's AHCA, a spokesperson from a national organization that provides information on health care fraud and an attorney who specializes in health care law -- who all agree that Saunders is likely right. At PolitiFact Florida, we dig for data to support claims by politicians -- and Saunders and our experts haven't provided hard numbers to prove him right. But the fact that four experts -- including one appointed by a Republican governor -- generally back up the Democratic minority leader or say that the two counties are at least among the worst in the nation carries weight with us." Claim: The two worst counties for (Medicaid) fraud in the country -- not state -- are Dade and Broward county.

A: Ron Saunders says Miami-Dade, Broward rule the country in Medicaid fraud
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Q: Paragraph: The final recommendations, issued by the U.S. Preventive Services Task Force and published in the Annals of Internal Medicine, apply to people aged 55 to 80 whose smoking has put them at high risk of cancer. That includes former heavy smokers who have quit within the past 15 years. Heavy smokers are considered to be those who smoked a pack a day for 30 years, or two packs a day for 15 years. According to a comprehensive review of medical evidence since 2004, the panel found the benefits of screening high-risk individuals with low-dose computed tomography, or CT scans, outweigh the potential harms of overdiagnosis and increased exposure to radiation, which also contribute to cancer risk. The panel, which is comprised of independent experts and advises U.S. policymakers, gave the screening a “B” recommendation, meaning it is at least moderately certain that the benefits of the scans outweigh the harms. Under the Affordable Care Act, insurers are required to cover preventive services with a grade of “B” or higher. The guidelines are intended to help prevent some of the 160,000 annual lung cancer deaths in the United States, which exceed the total number of deaths from breast, prostate and colon cancer combined. Smoking is the biggest risk factor for developing lung cancer, resulting in about 85 percent of lung cancers in the United States. The guidelines largely fall in line with recommendations from most major groups of cancer experts, including the American Cancer Society and the American Society of Clinical Oncology. When the initial recommendations were published in July, some doctors expressed concern that the guidelines could lead to overdiagnosis and overtreatment of cancers, in much the same way that widespread screening programs for breast and prostate cancers have done. Claim: Some current, former smokers should get annual lung scans: US panel.

A:
Heavy smokers and former heavy smokers should get annual lung cancer screening tests, according to final guidelines issued on Monday by an influential U.S. panel.
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