Given a paragraph, generate a claim that is supported by the given paragraph. 1) The claim must contain information from within the paragraph. 2) A sentence within the paragraph can be used as a claim. 3) The claim should not have contradictions within the paragraph. 4) The claim should be at most one sentence long.

[Q]: They found several creams caused skin cancer in the specially bred mice, which had been pre-treated with ultraviolet radiation. The cancers are not melanoma, the deadliest kind of skin cancer, they stressed in their report in the Journal of Investigative Dermatology, but another type called squamous cell carcinoma. Such tumours are slow growing, highly treatable and only fatal if patients fail to have them removed. Allan Conney and colleagues at Rutgers University in New Jersey said they discovered the risk while testing a theory that caffeine could prevent skin cancer. “We sort of got into this by accident,” Conney said in a telephone interview. “We wanted a safe cream that we could put the caffeine into.”   They were testing specially bred albino mice, which are prone to develop skin cancer. The mice are pre-treated with ultraviolet radiation to simulate the effects of a human who has had heavy sun exposure in the past but then stopped — something that may be happening in the population as people realize the risks of getting a tan. Conney’s team decided to test the creams first and found that all four they tested caused tumours to grow on the mice. He said he does not know why, but suspects two ingredients — mineral oil and sodium laurel sulphate. “We’d like to understand the mechanism. What is most important is to see whether these moisturizing creams are tumorigenic in people,” Conney said. He said his lab is not equipped to do this but someone should. But he added, “I don’t think that people should be scared because this is a mouse study and we don’t know whether or not it applies to humans.”   Other experts were sceptical about the study. “This is a pretty artificial situation with the mouse skin primed by a lot of UV light to develop cancer,” Karol Sikora, Medical Director of Cancer Partners U.K. in Britain, said in a statement. Dr. Jonathan Rees, an expert in dermatology at the University of Edinburgh in Scotland, said squamous cell carcinoma was not a big health worry. “Non-melanoma skin cancer in man is very, very common and is almost 100 percent curable with an operation usually simpler than a tooth filling,” Rees said in a statement. Conney said the mouse was a commonly used model in skin cancer but said he agreed that it does not perfectly replicate human skin and human behaviour. He said his team approached Johnson & Johnson to create a cream without the suspect products and they developed one using other readily available ingredients. “They are things that are commonly used in many moisturizing creams,” he said. This cream did not cause the tumours in the mice, they said. He said Rutgers and Johnson & Johnson had patented the new cream jointly but did not know whether it would be commercially developed. A spokesman at the company was not immediately available for comment.
[A]: Skin creams seen to cause tumours on mice.


[Q]: The test examines more than 2 million spots in a person’s genetic code, seeking variants that individually nudge a person’s obesity risk up by a tiny amount. The researchers drew on previously published data about those variants to create a risk score. A high score didn’t guarantee obesity, nor a low score rule it out. But middle-aged people with scores in the top 10 percent were 25 times as likely to be severely obese as those in the bottom 10 percent, scientists reported in a paper released Thursday by the journal Cell. Those two groups were separated by an average weight difference of about 29 pounds (13 kilograms), researchers said. Analysis showed the genetic propensity to obesity began having an effect on weight around age 3. Up to about age 8, “you might be able to make a difference in the kids who are born susceptible to obesity,” said one author of the study, Dr. Sekar Kathiresan of Massachusetts General Hospital in Boston and the Broad Institute of MIT and Harvard. But it will take further research to see whether intervening would work, Kathiresan said. The results for middle age came from a study of about 288,000 people. Overall, the risk-score research included data from more than 300,000 people at various ages. Severe obesity was defined as a body mass index of 40 or more. Results show genetic inheritance “plays a large role in how heavy one gets,” Kathiresan said. The risk score probably takes about half of a person’s genetic propensity into account, he said, and it shows similar accuracy in predicting ordinary obesity, defined as a BMI of 30 or more. Even if one inherits a propensity for obesity, he said, “you still have control over your fate. You’re not fated to be obese, but it’s very clear those individuals who’ve inherited susceptibility have to work that much harder to keep the weight off.” Among study participants with the highest scores, he noted, 17 percent were of normal weight. Other analyses show that people who remain lean despite an inherited propensity for obesity tend to eat better and have more physical activity than others with a high score who got fat. “So you can do something about it,” he said. Ruth Loos, a professor of environmental medicine and public health who did not participate in the study, said the risk score explains more of people’s genetic tendency than previous studies did. But she doubted it would be useful in a doctor’s office. It is “never going to be a good predictor,” said Loos, of the Icahn School of Medicine at Mt. Sinai in New York. She noted that in one test of the score’s predictive power, only 58 of the 371 subjects scoring in the top 10 percent ended up severely obese. And many other severely obese people didn’t score in the top 10 percent, she said. Simply asking about family history of obesity would probably work better, she said. The large role of lifestyle in obesity means a purely gene-based predictor will never be perfect, she said. Kathiresan, a cardiologist, said the risk score is best seen as a risk indicator, like high cholesterol. Most people with high cholesterol don’t get heart attacks, he said, but they do run a higher risk than others. Jason Boardman of the University of Colorado Boulder said genetic variants might affect body size indirectly, through an impact on lifestyles or other social and behavioral traits. Other research suggests the effect of genes on size depends on what kind of social and physical environment a person lives in, including such factors as access to unhealthy foods, he said in an email. ___ The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.
[A]: Study: Genetic test predicts middle-aged obesity risk.


[Q]: Only one quarter of children aged 6 to 15 meet the current guidelines of 60 minutes of moderate physical activity per day, said Dr. Russell R. Pate, chairman of the non-profit National Physical Activity Plan (NPAP) Alliance, which issued the first U.S. report card on Physical Activity for Children and Youth. “Fifty percent of waking hours are spent in sedentary activity,” said Pate, professor in the Department of Exercise Science in the Arnold School of Public Health at the University of South Carolina. Fitness experts say it is up to parents and policy makers to get their children to be more active. “It’s not about grading the kids,” said Dr. Peter Katzmarzyk, a fellow of the American College of Sports Medicine and chairman of the research committee that issued the report card. “Kids want to be active, if they’re given the opportunity.” he said. “This is for us to change.”       The report is based on public data and provides a snapshot of the state of youth physical activity in America. The 2014 grades were bad, without a single top mark. NPAP evaluated 10 key indicators, from overall physical activity to organized sports participation, and the number of children who cycle or walk to school. It found that since 1969, the proportion of elementary and middle-school students walking or cycling to school dropped from 47.7 percent to 12 percent. “More kids these days live too far from the school they attend,” Pate said. “The social norm around this behavior has really changed, and not for the better.”        The report card did not come as a surprise for Brian Sanders of i9 Sports, which provides camps and clinics for boys and girls aged 3 to 14 in sports such as flag (no-contact) football, soccer, basketball and baseball. “Public schools don’t have funding to support athletic programs and both parents working don’t have the time to get kids to activities,” he said. “Then there’s the increase in digital use. It all adds up.”       Sanders added that many parents are also concerned about safety aspects of playing in the neighborhood, and organized sports too often putting the emphasis on competition over fun. Katzmarzyk said the report also reflects socio-economic disparities. “Kids who come from higher incomes are participating (in sports),” he said.”Lower economic groups are not participating. There’s a lot more work to do to make these activities available to everyone.”       Katzmarzyk said the U.S. is one of 15 countries that compiled the report card, which will be the first of many. It is an advocacy tool aimed at the adult decision makers, he added.
[A]:
U.S. youth activity report card gives poor grades to adults.