In this task, you're given a paragraph and title from the research paper. Your task is to classify whether the given title is suitable or not for the research paper based on the given paragraph. Return "True" if title is proper according to paragraph else "False".

[Q]: Paragraph: A substantial proportion of hitherto unexplained respiratory tract illnesses is associated with human metapneumovirus (hMPV) infection. This virus also was found in patients with severe acute respiratory syndrome (SARS). To determine the dynamics and associated lesions of hMPV infection, six cynomolgus macaques (Macaca fascicularis) were inoculated with hMPV and examined by pathological and virological assays. They were euthanized at 5 (n ‫؍‬ 2) or 9 (n ‫؍‬ 2) days post-infection (dpi), or monitored until 14 dpi (n ‫؍‬ 2). Viral excretion peaked at 4 dpi and decreased to zero by 10 dpi. Viral replication was restricted to the respiratory tract and associated with minimal to mild, multi-focal erosive and inflammatory changes in conducting airways, and increased numbers of macrophages in alveoli. Viral expression was seen mainly at the apical surface of ciliated epithelial cells throughout the respiratory tract, and less frequently in type 1 pneumocytes and alveolar macrophages. Both cell tropism and respiratory lesions were distinct from those of SARS-associated coronavirus infection, excluding hMPV as the primary cause of SARS. This study demonstrates that hMPV is a respiratory pathogen and indicates that viral replication is short-lived, polarized to the apical surface, and occurs primarily in ciliated respiratory epithelial cells. 
 Title: Short Communication Experimental Human Metapneumovirus Infection of Cynomolgus Macaques (Macaca fascicularis) Results in Virus Replication in Ciliated Epithelial Cells and Pneumocytes with Associated Lesions throughout the Respiratory Tract
[A]: True


[Q]: Paragraph: Viruses of the Ebolavirus genus cause sporadic epidemics of severe and systemic febrile disease that are fueled by human-to-human transmission. Despite the notoriety of ebolaviruses, particularly Ebola virus (EBOV), as prominent viral hemorrhagic fever agents, and the international concern regarding Ebola virus disease (EVD) outbreaks, very little is known about the pathophysiology of EVD in humans and, in particular, about the human immune correlates of survival and immune memory. This lack of basic knowledge about physiological characteristics of EVD is probably attributable to the dearth of clinical and laboratory data gathered from past outbreaks. The unprecedented magnitude of the EVD epidemic that occurred in West Africa from 2013 to 2016 has allowed, for the first time, evaluation of clinical, epidemiological, and immunological parameters in a significant number of patients using state-of-the-art laboratory equipment. This review will summarize the data from the literature regarding human pathophysiologic and immunologic responses to filoviral infection. 
 Title: Ebola Virus Disease in Humans: Pathophysiology and Immunity
[A]: False


[Q]: Paragraph: The Ϫ2/Ϫ1 programmed ribosomal frameshifting (Ϫ2/Ϫ1 PRF) mechanism in porcine reproductive and respiratory syndrome virus (PRRSV) leads to the translation of two additional viral proteins, nonstructural protein 2TF (nsp2TF) and nsp2N. This Ϫ2/Ϫ1 PRF mechanism is transactivated by a viral protein, nsp1␤, and cellular poly(rC) binding proteins (PCBPs). Critical elements for Ϫ2/Ϫ1 PRF, including a slippery sequence and a downstream C-rich motif, were also identified in 11 simarteriviruses. However, the slippery sequences (XXXUCUCU instead of XXXUUUUU) in seven simarteriviruses can only facilitate Ϫ2 PRF to generate nsp2TF. The nsp1␤ of simian hemorrhagic fever virus (SHFV) was identified as a key factor that transactivates both Ϫ2 and Ϫ1 PRF, and the universally conserved Tyr111 and Arg114 in nsp1␤ are essential for this activity. In vitro translation experiments demonstrated the involvement of PCBPs in simarterivirus Ϫ2/Ϫ1 PRF. Using SHFV reverse genetics, we confirmed critical roles of nsp1␤, slippery sequence, and C-rich motif in Ϫ2/Ϫ1 PRF in SHFV-infected cells. Attenuated virus growth ability was observed in SHFV mutants with impaired expression of nsp2TF and nsp2N. Comparative genomic sequence analysis showed that key elements of Ϫ2/Ϫ1 PRF are highly conserved in all known arteriviruses except equine arteritis virus (EAV) and wobbly possum disease virus (WPDV). Furthermore, Ϫ2/Ϫ1 PRF with SHFV PRF signal RNA can be stimulated by heterotypic nsp1␤s of all non-EAV arteriviruses tested. Taken together, these data suggest that Ϫ2/Ϫ1 PRF is an evolutionarily conserved mechanism employed in non-EAV/-WPDV arteriviruses for the expression of additional viral proteins that are important for viral replication. 
 Title: Programmed ؊2/؊1 Ribosomal Frameshifting in Simarteriviruses: an Evolutionarily Conserved Mechanism
[A]:
False