instruction:
Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.
question:
The potential for progressive brain injury and subsequent disability related to intraventricular IL-2 therapy is discussed.
answer:
adverse drug event


question:
Two patients are described who developed sensory neuropathy after the ingestion of 30.6 and 114 g metronidazole respectively.
answer:
adverse drug event


question:
Some of these patients exhibit marked bradycardia (more than 20% deviation from the lowest age-adjusted normal values) while maintaining an arterial blood pressure within an acceptable normal range.
answer:

non-adverse drug event