Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

[Q]: Most sedimentary rocks form from sediments. Sediments are small pieces of other rocks, like pebbles, sand, silt, and clay. Sedimentary rocks may include fossils. Fossils are materials left behind by once-living organisms. Fossils can be pieces of the organism, like bones. They can also be traces of the organism, like footprints. Most often, sediments settle out of water (Figure 4.13). For example, rivers carry lots of sediment. Where the water slows, it dumps these sediments along its banks, into lakes and the ocean. When sediments settle out of water, they form horizontal layers. A layer of sediment is deposited. Then the next layer is deposited on top of that layer. So each layer in a sedimentary rock is younger than the layer under it. It is older than the layer over it. Sediments are deposited in many different types of environments. Beaches and deserts collect large deposits of sand. Sediments also continuously wind up at the bottom of the ocean and in lakes, ponds, rivers, marshes, and swamps. Avalanches produce large piles of sediment. The environment where the sediments are deposited determines the type of sedimentary rock that can form. Sedimentary rocks form in two ways. Particles may be cemented together. Chemicals may precipitate. Over time, deposited sediments may harden into rock. First, the sediments are compacted. That is, they are squeezed together by the weight of sediments on top of them. Next, the sediments are cemented together. Minerals fill in the spaces between the loose sediment particles. These cementing minerals come from the water that moves through the sediments. These types of sedimentary rocks are called clastic rocks. Clastic rocks are rock fragments that are compacted and cemented together. Clastic sedimentary rocks are grouped by the size of the sediment they contain. Conglomerate and breccia are made of individual stones that have been cemented together. In conglomerate, the stones are rounded. In breccia, the stones are angular. Sandstone is made of sand-sized particles. Siltstone is made of smaller particles. Silt is smaller than sand but larger than clay. Shale has the smallest grain size. Shale is made mostly of clay-sized particles and hardened mud. Chemical sedimentary rocks form when crystals precipitate out from a liquid. The mineral halite, also called rock salt, forms this way. You can make halite! Leave a shallow dish of salt water out in the Sun. As the water evaporates, salt crystals form in the dish. There are other chemical sedimentary rocks, like gypsum. Table 4.1 shows some common types of sedimentary rocks and the types of sediments that make them up. Picture Rock Name Conglomerate Type of Sedimentary Rock Clastic Breccia Clastic Sandstone Clastic Siltstone Clastic Limestone Bioclastic Coal Organic Picture Rock Name Rock Salt Type of Sedimentary Rock Chemical precipitate
[A]: What are solid particles that have been deposited on the Earths surface called?


[Q]: Chronic myeloid leukemia (CML) is arguably the best understood of all human malignancies. Its origins in the hematopoietic stem cell can be traced to a reciprocal translocation involving chromosomes 9 and 22, dubbed the Philadelphia chromosome, which is observed in essentially all patients. The resulting fusion gene, BCR/ABL, encodes an activated tyrosine kinase that can act alone to induce a CML-like syndrome in mouse models. These animal models have validated BCR/ABL as a target for the development of specific pharmaceutical inhibitors. The kinase inhibitor imatinib mesylate (Gleevec) is highly specific, effective, and minimally toxic, but may not effect cures as a single agent, particularly in patients with accelerated and blast-phase disease. Resistance to imatinib can confound therapy. Surprisingly, a high percentage of resistant cases manifest intact or augmented BCR/ABL signaling, suggesting that this oncoprotein, or signaling pathways emanating from it, remain viable targets. Combination chemotherapy is under active investigation, and among the most compelling strategies is dual treatment with agents that both target BCR/ABL signal transduction. BCR/ABL activates Ras, and compounds designed to antagonize Ras function called farnesyl transferase inhibitors (FTIs) have shown potent activity in vitro and in animal models of BCR/ABL-induced leukemia. Initial clinical trials in patients with refractory acute myeloid leukemia and CML in blast crisis have shown significant activity, suggesting that trials combining imatinib and FTIs are warranted.
[A]: What tyrosine kinase, involved in a Philadelphia- chromosome positive chronic myelogenous leukemia, is the target of Imatinib (Gleevec)?


[Q]: This March is a busy month in Shanghai.There's a lot to do.Here are the highlights. Live Music - Late Night Jazz Enjoy real American jazz from Herbie Davis, the famous trumpet player.He's coming with his new 7-piece band, Herbie's Heroes.Herbie is known to play well into the early hours, so don't expect to get much sleep.This is Herbie's third visit to Shanghai.The first two were sold out, so get your tickets quickly. PLACE: The Jazz Club DATES: 15---23 March PRICE: Y=80,120 TIME: 10:00p.m.till late! TEL: 6466--8736 Scottish dancing Take your partners and get ready to dance till you drop.Scottish dancing is fun and easy to learn.Instructors will demonstrate the dances.The live band, Gordon Stroppie and the Weefrees, are also excellent. PLACE: Jack Stein's DATES: every Monday PRICE: Y60 including one drink TIME: 7:00 ---0:00 p.m. TEL: 6402-1877 Exhibitions - Shanghai Museum There are 120,000 pieces on show here.You can see the whole of Chinese history under one roof.It's always interesting to visit, but doubly so at the moment with the Egyptian Tombs exhibition.There are lots of mummies and more gold than you've ever seen before.Let us know if you see a mummy move! PLACE: Shanghai Museum PRICE: Y=30 (Y= 15 for students) TEL: 6888-6888 DATES: daily TIME: Monday - Friday 9:00a.m.- 5:00p.m., Weekends 9:00a.m.--- 9:00p.m. Dining - Sushi chef in town Sushi is getting really big in Shanghai.In Japan, it's become an art form.The most famous Sushi 'artist' is Yuki Kamura.She's also one of the few female chefs in Japan.She'll be at Sushi Scene all of this month. PLACE: Sushi Scene in the Shanghai Hotel DATES: all month PRICE: Y=200 TIME: lunchtime TEL: 6690-3211 For a full listing of events, see our website.
[A]:
Suppose you are going to attend an activity at 8: 00p.m.on Saturday, which one can   you choose?