In this task, you are given a passage which has a question and the context. You have to generate an answer to the question based on the information present in the context.

[Q]: Context: The gene(s) encoding for endomorphin precursor(s) is/are still unknown. We have raised the possibility of and did find some evidence for a potential de novo biosynthetic route starting from Tyr-Pro precursor. To pursue further this possibility we measured the generation of immunoreactive endomorphin-2 (E2-IR) in adult rat isolated L4,5 dorsal root ganglia.\Question: Is immunoreactive endomorphin 2 generated extracellularly in rat isolated L4,5 dorsal root ganglia by DPP-IV?
[A]: In rat isolated dorsal root ganglia the combination of presumed biosynthetic precursor of endomorphin 2 (E2), Tyr-Pro with the dipeptidyl peptidase IV (DPP-IV) inhibitor Ile-Pro-Ile generated 1.60+/-0.37 pg/mg Wet Tissue Weight_30 min E2-IR in the bathing fluid (n=4) with an 8-fold increase upon depolarization whereas the tissue content was low (0.50+/-0.08 pg/mg_WTW). Substance P, as determined by ELISA in the pilot experiments, was found almost exclusively within the tissues. It is concluded that E2-IR was generated extracellularly by a membrane-bound DPP-IV, which was switched to "synthase" mode by the hydrolase inhibitor Ile-Pro-Ile. DPP-IV was depolarization-sensitive in "synthase" functional mode.


[Q]: Context: The aim of this study was to investigate the attitudes and perceptions of staff radiologists regarding the incorporation of a nonanonymous peer review system at an academic hospital.', 'A questionnaire gauging knowledge of, attitudes toward, and perceptions regarding peer review was distributed to all staff radiologists at a large academic hospital. The survey was distributed before the implementation of a nonanonymous peer review system. Data were analyzed using descriptive statistics. Responses were cross-tabulated according to subspecialty and number of years in practice.', 'The majority of respondents agreed that peer review is important for improving patient care (31 of 36 [86%]) and professional development (29 of 36 [81%]), but the vast majority (33 of 36 [92%]) believed that peer review should be anonymous. Twenty-six of 36 respondents (72%) believed that peer review will not be safe from malpractice issues, 24 of 36 (67%) agreed that it has the potential to damage interpersonal relationships within the department, and 15 of 36 (42%) believed that it may influence their job security or rankings within the department. Significant differences were identified between radiologists with more and fewer years of practice experience.\Question: Do survey of radiologist attitudes and perceptions regarding the incorporation of a departmental peer review system?
[A]: The incorporation of a nonanonymous peer review system generates anxiety and uncertainty within a radiology department. The investigation of physicians' attitudes toward and perceptions about peer review is important for understanding the potential impact not only on patient care but also on radiologists' relationships and psychology in the workplace.


[Q]: Context: Little is known about behaviors associated with successful weight loss during adolescence. The first objective of the current study was to identify meaningful weight loss, weight maintenance, and weight gain in male and female adolescents. The second objective of this study was to apply these methods to U.S. adolescents from the National Health and Nutrition Survey 1999 to 2002 data and to identify factors associated with these weight change outcomes.', 'The current analyses include 1726 (female, 836; male, 890) 16- to 18-year-old adolescents who completed the questionnaire components and interview for either the 1999-2000 or the 2001-2002 National Health and Nutrition Survey study. Dietary intake, physical activity, and dieting attitudes were compared across the weight loss (L), maintain (M), and gain (G) groups in the entire sample and in a subset of adolescents who are overweight and at-risk-for-overweight (> or = 85th percentile).', 'The tested method for identifying weight L, M, and G groups has both theoretical and statistical validity and, when applied to the sample, showed the expected direction of changes in weight. Results suggest that more overall physical activity, more vigorous exercise, and less sedentary activity are associated with being in the L group in both the full sample and the overweight and at-risk-for-overweight sample. In addition, fewer teens in the L groups endorsed efforts at trying to lose weight, compared with the M and G groups.\Question: Does identification and correlate of weight loss in adolescents in a national sample?
[A]:
This study provides a method to determine successful adolescent weight loss for researchers and provides useful concrete information about successful weight loss for clinicians and others who work with adolescents.