Given a context passage, generate a question from the passage such that its answer is shortest continous span from the passage.

Ex Input:
The nationwide prevalence of latent tuberculosis infection (LTBI) in Italian patients with psoriasis has never been investigated. To estimate the nationwide prevalence of LTBI in Italian patients with psoriasis who are candidates for systemic treatment. Data were obtained from the Psocare Registry on those patients (n=4946) with age >18years, systemic treatment at entry specified and tuberculin skin test (TST) performed according to the Mantoux method. LTBI diagnosis was based on a positive TST result in the absence of any clinical, radiological or microbiological evidence of active tuberculosis. Latent tuberculosis infection was diagnosed in 83% of patients with psoriasis (409 of 4946). The prevalence of LTBI was lower in patients on biologics than in those on conventional systemic treatments, ranging from 43% (19 of 444) of patients on adalimumab to 31% (eight of 26) of those on psoralen-ultraviolet A (P<005). Independent factors associated with LTBI were male sex [odds ratio (OR) 130, 95% confidence interval (CI) 104-162; P=002], age over 55years (OR 293, 95% CI 218-393; P<0001) and being entered into a conventional treatment (OR 383, 95% CI 310-474; P<0001). Positive history of tuberculosis was seen in 1% of patients (n=49). The nationwide prevalence of LTBI in Italian patients with psoriasis candidate to systemic treatment is high, and screening is recommended prior to biological treatment.

Ex Output:
The Mantoux test detects what latent infection/disease?


Ex Input:
In the United States Federal Budget for 2010, entitled 'A New Era of Responsibility', the DHS was allocated a discretionary budget of $42.7 billion . The end-of-yearDHS Annual Financial Report for financial year 2010 showed a net cost of operations of $56.4 billion , out of total budgetary resources of $83.2 billion . The components with the highest net cost were US Coast Guard , U.S. Customs and Border Protection , and Federal Emergency Management Agency . Revenues of $10.4 billion were generated in the year . According to the Washington Post, "DHS has given $31 billion in grants since 2003 to state and local governments for homeland security and to improve their ability to find and protect against terrorists, including $3.8 billion in 2010."

Ex Output:
Which was higher the DHS net coast of operations or their total budgetary resources?


Ex Input:
Why should mankind explore space? Why should money, time and effort be spent exploring and researching something with so few obvious benefits? Why should resources be spent on space rather than on conditions and people on Earth? These are questions that, understandably, are very often asked. Perhaps the best answer lies in our genetic makeup as human beings. What drove our ancestors to move from the trees into the plains, and on into all possible areas and environments? The wider the spread of a species, the better its chance of survival. Perhaps the best reason for exploring space is this genetic tendency to expand wherever possible. Nearly every successful civilization has explored, because by doing so, any dangers in surrounding areas can be identified and prepared for. Without knowledge, we may be completely destroyed by the danger. With knowledge, we can lessen its effects. Exploration also allows minerals and other potential resources to be found. Even if we have no immediate need of them, they will perhaps be useful later. Resources may be more than physical possessions . Knowledge or techniques have been gained through exploration. The techniques may have medical applications which can improve the length or quality of our lives. We have already benefited from other spin-offs including improvements in earthquake prediction, in satellites for weather forecasting and in communications systems. Even non-stick pans and mirrored sunglasses are by-products of technological developments in the space industry! While many resources are spent on what seems a small return, the exploration of space allows creative, brave and intelligent members of our species to focus on what may serve to save us. While space may hold many wonders and explanations of how the universe was formed or how it works, it also holds dangers. The danger exists, but knowledge can help human being to survive. Without the ability to reach out across space, the chance to save ourselves might not exist. While Earth is the only planet known to support life, surely the adaptive ability of humans would allow us to live on other planets. It is true that the lifestyle would be different, but human life and cultures have adapted in the past and surely could in the future.

Ex Output:

What makes it possible for humans to live on other planets?