In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Q: Question: In mammals, Toll-like receptors (TLRs) are receptors: 
 Options:  <1> Signaling. <2> Antigenic <3> Of histocompatibility alleles. <4> Of phagocytosis. <5> Of chemokines.

A: 1
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Q: Question: With what scope is the Theory of the Melzack Gate and Wall related ?: 
 Options:  <1> Cancer. <2> HIV infection <3> Renal problems. <4> Pain. <5> Cardiovascular disorders

A: 4
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Q: Question: In consecutive reactions of first order, the global kinetic constant: 
 Options:  <1> Presents units of concentration-1 time-1. <2> Presents units of time-1. <3> Equivalent to the ratio of the kinetic constants of each stage. <4> Corresponds to the sum of the kinetic constants of each stage. <5> Equivalent to the product of the kinetic constants of each stage.

A:
2
****