Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does constitutive secretion of Interleukin-4 dictate CD133+ side population cells to resist drug treatment and cell death?
Answer: Our data suggest that the autocrine secretion of IL-4 is a potential target for the development of novel anticancer drugs to prevent the CSCs-mediated therapy failure and tumorigenesis.
yes

Question: Does preinjury beta blocker usage affect the heart rate response to initial trauma resuscitation?
Answer: Preinjury beta blockade is associated with a slower presenting heart rate, more bradycardia, less tachycardia, but no difference in mortality or ability to achieve a normal heart rate with resuscitation.
no

Question: Is pilot study on the correlation between skin auto-fluorescence and serum antioxidant enzyme : skin auto-fluorescence negatively associated with levels of malondialdehyde?
Answer: We determined that skin AF intensity of the photo-protected area reflects intrinsic skin aging. In addition, degree of photo-aging could be indirectly inferred by skin AF of photo-exposed area and serum MDA level.

yes