In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Example Input: Question: Question linked to image nº15 A 67-year-old patient who reported a decrease in unilateral visual acuity and rapidly evolving metamorphopsia. The attached retinography presents the image of the affected eye. The most likely diagnosis would be: 
 Options:  <1> Macular degeneration associated with exudative age. <2> Retinal detachment. <3> Retinitis pigmentosa <4> Central vein thrombosis of the ischemic retina. <5> Equatorial choroidal melanoma.
Example Output: 1

Example Input: Question: A plasmid contains necessarily: 
 Options:  <1> Genes of resistance to antibiotics. <2> Origin of replication. <3> Integrons <4> Genes of transfer by conjugation. <5> Transposons.
Example Output: 2

Example Input: Question: The 2-microglobulin: 
 Options:  <1> It is a low molecular weight immunoglobulin. <2> It is found in high concentration in platelets. <3> It filters freely through the glomerulus and is secreted by the tubule. <4> It is absent in urine. <5> It is found on the surface of all nucleated cells.
Example Output:
5