Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: The anti-epileptic agent trimethadione was given orally to 30 outpatients at a dose of 0.9-1.5 g daily.

Output: non-adverse drug event


Input: Consider Input: One patient who received clindamycin had liver biopsy findings of marked cholestasis, portal inflammation, bile duct injury and bile duct paucity (ductopenia).

Output: adverse drug event


Input: Consider Input: Mefloquine-associated hypoglycaemia in a cachectic AIDS patient.


Output: adverse drug event