This task is about reading the given passage and construct a question about the information present in the passage. Construct a question in such a way that (i) it is unambiguous, (ii) it is answerable from the passage, (iii) its answer is unique (iv) its answer is a continuous text span from the paragraph. Avoid creating questions that (i) can be answered correctly without actually understanding the paragraph and (ii) uses same words or phrases given in the passage.

[Q]: In prokaryotes, transcription occurs in the cytoplasm; for very long transcripts, translation may begin at the 5' end of the RNA while the 3' end is still being transcribed. In eukaryotes, transcription occurs in the nucleus, where the cell's DNA is stored. The RNA molecule produced by the polymerase is known as the primary transcript and undergoes post-transcriptional modifications before being exported to the cytoplasm for translation. One of the modifications performed is the splicing of introns which are sequences in the transcribed region that do not encode protein. Alternative splicing mechanisms can result in mature transcripts from the same gene having different sequences and thus coding for different proteins. This is a major form of regulation in eukaryotic cells and also occurs in some prokaryotes.:7.5
[A]: Where does transcription occur in prokaryotes?


[Q]: Both intensive and free-range farming have animal welfare concerns. In intensive systems, cannibalism, feather pecking and vent pecking can be common, with some farmers using beak trimming as a preventative measure. Diseases can also be common and spread rapidly through the flock. In extensive systems, the birds are exposed to adverse weather conditions and are vulnerable to predators and disease-carrying wild birds. Barn systems have been found to have the worst bird welfare. In Southeast Asia, a lack of disease control in free-range farming has been associated with outbreaks of avian influenza.
[A]: What are some of the major concerns with intensive breeding programs?


[Q]: According to Genius, the James Gleick-authored biography, Feynman tried LSD during his professorship at Caltech. Somewhat embarrassed by his actions, he largely sidestepped the issue when dictating his anecdotes; he mentions it in passing in the "O Americano, Outra Vez" section, while the "Altered States" chapter in Surely You're Joking, Mr. Feynman! describes only marijuana and ketamine experiences at John Lilly's famed sensory deprivation tanks, as a way of studying consciousness. Feynman gave up alcohol when he began to show vague, early signs of alcoholism, as he did not want to do anything that could damage his brain—the same reason given in "O Americano, Outra Vez" for his reluctance to experiment with LSD.
[A]:
What substance did Feynman give up later in life?