Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Input: Consider Input: Question: Does single copy of variant CYP2A6 alleles confer susceptibility to liver dysfunction in patients treated with coumarin?
Answer: No evidence was obtained that the studied polymorphism in CYP2A6 is a determinant of the coumarin-associated liver dysfunction.

Output: no


Input: Consider Input: Question: Do changes in basophil activation during grass-pollen sublingual immunotherapy correlate with clinical efficacy?
Answer: Allergen reactivity of peripheral blood basophils is not a biomarker for adverse events or early onset of clinical responses to SLIT.

Output: no


Input: Consider Input: Question: Does macrophage-activating lipopeptide-2 require Mal and PI3K for efficient induction of heme oxygenase-1?
Answer: These results indicated that MALP-2 required TLR2/6, Btk, Mal and c-Src to activate PI3K, which in turn initiated the activation of Nrf2 for efficient HO-1 induction.


Output: yes