Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
Retinopathy of prematurity (ROP) is a multifactorial disease affecting the developing retinal vasculature and remains an important cause of blindness in very preterm infants.

Ex Output:
non-adverse drug event


Ex Input:
This avoids the need for bronchoscopic examination or transfer of the patient for computed tomography.

Ex Output:
non-adverse drug event


Ex Input:
Lithium therapy was discontinued because of poor compliance to the medication and intolerable polyuria.

Ex Output:

adverse drug event