In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Q: Question: The reaction product of cyclohexanone with bromine catalyzed by a base is: 
 Options:  <1> 2-Bromocyclohexanone. <2> 2,2-Dibromocyclohexanone. <3> 2,2,6-Tribomociclohexanona. <4> 1,1-Dibromocyclohexane. <5> 2,2,6,6-Tetrabromocyclohexanone.

A: 5
****
Q: Question: The probability that a person free of a disease develops it during a period of time, corresponds to: 
 Options:  <1> Chance. <2> Prevalence <3> Specificity <4> Forecast. <5> Risk.

A: 5
****
Q: Question: The hepatic clearance of a drug, mainly eliminated by metabolism, which has a high degree of hepatic extraction and a high binding to plasma proteins: 
 Options:  <1> It is significantly influenced by the hepatic blood flow. <2> It is significantly influenced by changes in the degree of plasma protein binding. <3> It is significantly influenced both by hepatic blood flow and by changes in the degree of plasma protein binding. <4> It will not be influenced by the hepatic blood flow or by changes in the degree of binding to plasma proteins. <5> It will depend on the absolute bioavailability of the drug.

A:
1
****