TASK DEFINITION: Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
PROBLEM: Question: Is diffuse musculoskeletal pain associated with low vitamin D levels or improved by treatment with vitamin D?
Answer: Low vitamin D levels are not associated with diffuse musculoskeletal pain, and treatment with vitamin D does not reduce pain in patients with diffuse pain who have low vitamin D levels.

SOLUTION: no

PROBLEM: Question: Are standard Radiographs Sufficient for Assessing Knee Mechanical Axis in Patients With Advanced Osteoarthritis?
Answer: Standard radiographs are not sufficient for determining MA, and HTA radiographs should be used while making surgical decisions aimed at correcting alignment to within ±3° or for assessing alignment post-total knee arthroplasty. In addition, surgical alignment outcomes reported in previous research using standard radiographs should be viewed with caution.

SOLUTION: no

PROBLEM: Question: Does the cytoprotective effect of biglycan core protein involve Toll-like receptor 4 signaling in cardiomyocytes?
Answer: The core protein of exogenous biglycan protects myocardial cells from SI/R injury via TLR4-mediated mechanisms involving activation of ERK, JNK and p38 MAP kinases and increased NO production. The cytoprotective effect of rhBGNc is due to modulation of SI/R-induced changes in necrosis, apoptosis and autophagy.

SOLUTION:
yes