instruction:
Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
question:
Question: Are biphasic redistribution of muscarinic receptor and the altered receptor phosphorylation and gene transcription underlying mechanisms in the rat heart during sepsis?
Answer: The m2AChR in the rat heart was externalized from light vesicles to sarcolemma (overexpression) during early sepsis but internalized from surface membranes to intracellular sites (underexpression) during late sepsis. Furthermore, changes in the receptor phosphorylation and gene transcription are responsible for the biphasic redistribution and the altered expression of m2AChR in the rat heart during the progression of sepsis.
answer:
yes


question:
Question: Is retinol-binding protein-4 strongly associated with insulin sensitivity in normal pregnancies?
Answer: The increased fat mass and insulin resistance during normal pregnancy was best explained by measures of fat mass. However, the increase in RBP4 from early to late pregnancy, associated with a decline in insulin sensitivity, potentially indicates interactions with glucose metabolism.
answer:
no


question:
Question: Does four-hour infusion of hydrocortisone suppress the nocturnal increase of circulating acyl- or desacyl-ghrelin concentrations in healthy young adults?
Answer: A short-term increase in circulating cortisol concentrations by exogenous hydrocortisone infusion does not suppress circulating nocturnal acyl- or desacyl-ghrelin concentrations. Thus, it is likely that the diurnal pattern of ghrelin secretion is under circadian control and not directly regulated by cortisol.
answer:

no