Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Q: Context: Our previous work has shown that gene knockout of the sodium-glucose cotransporter SGLT2 modestly lowered blood glucose in streptozotocin-diabetic mice (BG; from 470 to 300 mg/dl) and prevented glomerular hyperfiltration but did not attenuate albuminuria or renal growth and inflammation. Here we determined effects of the SGLT2 inhibitor empagliflozin (300 mg/kg of diet for 15 wk; corresponding to 60-80 mgkg(-1)day(-1)) in type 1 diabetic Akita mice that, opposite to streptozotocin-diabetes, upregulate renal SGLT2 expression. Akita diabetes, empagliflozin, and Akita + empagliflozin similarly increased renal membrane SGLT2 expression (by 38-56%) and reduced the expression of SGLT1 (by 33-37%) vs. vehicle-treated wild-type controls (WT). The diabetes-induced changes in SGLT2/SGLT1 protein expression are expected to enhance the BG-lowering potential of SGLT2 inhibition, and empagliflozin strongly lowered BG in Akita (means of 187-237 vs. 517-535 mg/dl in vehicle group; 100-140 mg/dl in WT). Empagliflozin modestly reduced GFR in WT (250 vs. 306 l/min) and completely prevented the diabetes-induced increase in glomerular filtration rate (GFR) (255 vs. 397 l/min). Empagliflozin attenuated increases in kidney weight and urinary albumin/creatinine ratio in Akita in proportion to hyperglycemia. Empagliflozin did not increase urinary glucose/creatinine ratios in Akita, indicating the reduction in filtered glucose balanced the inhibition of glucose reabsorption. Empagliflozin attenuated/prevented the increase in systolic blood pressure, glomerular size, and molecular markers of kidney growth, inflammation, and gluconeogenesis in Akita. We propose that SGLT2 inhibition can lower GFR independent of reducing BG (consistent with the tubular hypothesis of diabetic glomerular hyperfiltration), while attenuation of albuminuria, kidney growth, and inflammation in the early diabetic kidney may mostly be secondary to lower BG. 
 Question: Which protein does empagliflozin inhibit?

A: sglt2
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Q: Context: The Texans' ninth match was an AFC South rivalry match against the Jaguars at EverBank Field. In the first quarter the Texans trailed early as kicker Josh Scobee hit a 38-yard field goal. They replied after kicker Neil Rackers made a 24-yard field goal. They trailed again in the 2nd quarter with RB Maurice Jones-Drew getting a 3 and a 9-yard TD run. However, the lead didn't last long after RB Arian Foster got a 1-yard TD run, and QB Matt Schaub threw a 9-yard TD pass to WR Andre Johnson. The Jaguars stayed in the lead when QB David Garrard completed a 52-yard TD pass to TE Zach Miller, but the Texans replied again with Schaub finding WR Kevin Walter on an 18-yard TD pass. Suddenly, the Texans' defense broke through with only a few seconds remaining after Garrard made a 50-yard TD pass to WR Mike Thomas. The ball was batted into his hands by Texans Defensive back Glover Quin, who made an attempt to bat the ball to the ground. 
 Question: In what quarter did both teams score a field goal?

A: first quarter
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Q: Context: Die Jakobsleiter (Jacob's Ladder) is an oratorio by Arnold Schoenberg that marks his transition from a contextual or free atonality to the twelve-tone technique anticipated in the oratorio's use of hexachords. 
 Question: Which is the basis of Die Jakobsleiter?

A:
jacob's ladder
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