Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Input: Consider Input: She had a history of diabetes and angina pectoris.

Output: non-adverse drug event


Input: Consider Input: Hypoglycemia can be a serious side effect of etanercept in patients already on antidiabetic medications known to cause hypoglycemia, such as sulfonylureas, meglitinides, and insulin.

Output: adverse drug event


Input: Consider Input: Single and multiple verrucous plantaris lesions are well known for their resistance to conservative methods of treatment.


Output: non-adverse drug event