Adverse drug reactions are appreciably harmful or unpleasant reactions resulting from an intervention related to the use of medical products, which predicts hazard from future administration and warrants prevention or specific treatment, or alteration of the dosage regimen, or withdrawal of the product. Given medical case reports extracted from MEDLINE, the task is to classify whether the case report mentions the presence of any adverse drug reaction. Classify your answers into non-adverse drug event and adverse drug event.

Ex Input:
In more than 6,000 patient applications of rapid atrial pacing, there has been only one failure to convert the tachycardia.

Ex Output:
non-adverse drug event


Ex Input:
Induction of systemic lupus erythematosus by interferon-gamma in a patient with rheumatoid arthritis.

Ex Output:
adverse drug event


Ex Input:
G-banding analyses of bone marrow cells had repeatedly demonstrated normal male karyotype before this event, but t(9;22)(q34;q11) was demonstrated after the event.

Ex Output:

non-adverse drug event