Generate an explanation for the given claim using the provided supporting material from the paragraph. Please consider the following points while generating an output. 1) The claim will always have supporting proof in the paragraph, and the paragraph will have a clear point of view supporting the claim. 2) There can be instances where direct correlation to the claim is not available. Make use of the sentences in the paragraph to provide a corresponding output supporting the claim. 3) The explanation should be at least one and at most twelve sentences long.

Input: Consider Input: Paragraph: Limiting the quantity per dosage unit will reduce the risk of inadvertent overdose, which can lead to liver failure, liver transplant and death, the Food and Drug Administration said. It cited the fact that no available data showed that taking more than the recommended dose provided benefits that outweighed the added risks. (link.reuters.com/nen95v)  Inadvertent overdose from combination drugs containing acetaminophen, also known as paracetamol in most countries outside the United States, accounts for nearly half of all cases of acetaminophen-related liver failure in the United States, the agency said. Combination acetaminophen products are commonly prescribed to patients to treat pain from acute injuries, post-operative pain, or pain following dental procedures. In January 2011, the FDA asked manufacturers of combination drugs containing acetaminophen, sold globally under trade names such as Tylenol and Panadol, to limit acetaminophen doses to no more than 325 mg in each tablet or capsule by January 14, 2014. (link.reuters.com/hyn95v)  Some of these products still remain available, the agency said. The FDA also suggested that pharmacists who receive a prescription for a combination product with more than the recommended dose contact the prescriber to discuss using a lower dose. In the near future, the FDA plans to institute proceedings to withdraw approval for combination drugs that remain on the market, it said in a statement. Acetaminophen, one of the most commonly used drugs in the United States, is widely used in both prescription and over-the-counter products to reduce pain and fever. Claim: FDA asks doctors to limit acetaminophen in combination drugs.

Output: U.S. health regulators recommended on Tuesday that healthcare professionals stop prescribing combination drugs that contain more than 325 milligrams of acetaminophen per tablet, capsule, or other dosage unit, citing the risk of liver damage.


Input: Consider Input: Paragraph: Health authorities across Asia have been stepping up surveillance and other precautions to prevent a repeat of the disruptions and deaths during the 2003 SARS crisis, which caused $40 billion to $50 billion in losses from reduced travel and spending. The first cases of what has been identified as a novel coronavirus were linked to a seafood market in Wuhan, suggesting animal-to-human transmission, but it now is also thought to be spread between people. As of Wednesday, more than 500 people were confirmed infected and 17 had died from the illness, which can cause pneumonia and other severe respiratory symptoms. A retreat in financial markets on Tuesday was followed by a rebound on Wednesday, as investors snapped up bargains. Share benchmarks were mostly higher both in Asia, Europe  and the U.S. While the new virus appears much less dangerous than SARS, “the most significant Asia risk could lie ahead as the regional peak travel season takes hold, which could multiply the disease diffusion,” said Stephen Innes, chief Asian strategist for AxiCorp. “So, while the risk is returning to the market, the lights might not turn green until we move through the Lunar New Year travel season to better gauge the coronavirus dispersion.” The 2003 outbreak of Severe Acute Respiratory Syndrome in China, along with cases of a deadly form of bird flu, resulted in widespread quarantine measures in many Chinese cities and in Hong Kong. More than 8,000 people fell sick and just under 800 people died, a mortality rate of under 10%. While the ordinary flu kills hundreds of thousands of people each year, such new diseases raise alarm due to the uncertainties over how deadly they might be and how they might spread. That’s especially true during the annual mass travel of the Lunar New Year festival, which begins this week. “The cost to the global economy can be quite staggering in negative GDP terms if this outbreak reaches epidemic proportions,” Innes said in a report. In China, health officials stepped up screening for fevers. “We ask the public to avoid crowds and minimize the public gatherings to reduce the possibility of cross infection,” Li Bin, deputy director of the National Health Commission, said Wednesday. As with SARS, the impact of the disease is likely to fall heaviest on specific industries, such as hotels and airlines, railways, casinos and other leisure businesses and retailers, analysts said. In a statement on its website Wednesday, Shanghai Disney Resort said it was operating normally but understood if some guests wished to change their travel plans. The park said it would let guests reschedule their visits or refund their money. China’s Civil Aviation Administration called on airlines to offer free refunds for tickets in or out of Wuhan. “If the pneumonia couldn’t be contained in the short term, we expect China’s retail sales, tourism, hotel & catering, travel activities likely to be hit, especially in the first and second quarters,” said Ning Zhang of UBS. Government efforts to offset the shock would help, but growth will likely rebound less than earlier forecast, Zhang said. The outbreak is a boon, meanwhile, for pharmaceutical companies and makers of protective masks and other medical gear. As of Jan. 17, the World Health Organization had not recommended any international restrictions on travel but urged local authorities to work with the travel industry to help prevent the disease from spreading while warning travelers who fall ill to seek medical attention. The illness is yet another blow for Hong Kong, whose economy is reeling from months of often violent anti-government protests. The wider concern is China, where the economy  grew at a 30-year low 6.1% annual pace in 2019. An interim trade pact between Beijing and Washington had raised hopes that some pressure from tensions between the two biggest economies might ease, and the latest data have showed signs of improved demand for exports. The virus outbreak raises the risk such optimism might be premature. “We expect increased downward pressure on China’s growth, particularly in the services sector,” said Ting Lu and other analysts at Nomura in Hong Kong, who based their projections on the spread of the SARS virus. The growing number of global travelers has contributed to the spread of various diseases in recent years, including Middle East respiratory syndrome, the Ebola and Zika viruses, the plague, measles and other highly contagious illnesses. The World Economic Forum estimates that pandemics — cross-border outbreaks like the flu that killed 50 million people a century ago — have the potential to cause an $570 billion in annual economic losses. The 2014-16 Ebola virus epidemic caused losses amounting to over $2.2 billion, according to the World Bank. That includes a 40% decrease in the number of working Liberians at the height of the crisis, lower exports and harvests, and costs for combating the disease. Apart from the human tragedy, such crises gobble up resources needed for other government spending, exacting a harsh toll on the poorest economies. In Africa, the loss of health care workers to Ebola resulted in thousands more deaths of mothers and babies, hindered work on other diseases such as preventing and treating malaria, HIV/AIDS and tuberculosis, reduced vaccination rates and fewer surgeries, the World Bank said in a report. Many survivors, meanwhile, suffer from lingering effects of the illnesses and the powerful drugs used to save their lives, becoming more vulnerable to hunger and other risks. At the same time, increasingly sophisticated tools for collecting data and analyzing are aiding efforts to prepare for and cope with severe disease outbreaks. In 2016, the World Bank set up a $500 million rapid response insurance fund, working with the WHO and insurance companies, to combat pandemics in developing countries. The fund uses “cat bonds,” or catastrophe bonds, whose principal will be lost if the funds are needed to help deal with an outbreak. Private insurers have followed with products of their own meant to hedge against risks from such disasters. Claim: China virus outbreak may wallop economy, financial markets.

Output: News that a new virus that has afflicted hundreds of people in central China can spread between humans has rattled financial markets and raised concern it might wallop the economy just as it might be regaining momentum.


Input: Consider Input: Paragraph: The clarification, which some moral theologians called “groundbreaking,” was the latest step in what is already seen as a significant shift in Catholic Church policy. It came at a news conference to launch the pope’s new book, “Light of the World: The Pope, the Church, and the Sign of the Times.”   In the book, a long interview with German Catholic journalist Peter Seewald, the pope made clear he was not changing the Catholic ban on contraception, but, using the example of a male prostitute, said there were cases where using a condom to avoid transmitting the HIV virus could be justified. Vatican spokesman Father Federico Lombardi made the clarification because the German, English and French versions of the book used the male article when referring to a prostitute, but the Italian version used the female form. “I asked the pope personally if there was a serious distinction in the choice of male instead of female and he said ‘No’,” Lombardi said. “The point is it (condom use) should be a first step toward responsibility in being aware of the risk of the life of the other person one has relations with,” he said. “If it is a man, a woman or a transsexual who does it, we are always at the same point, which is the first step in responsibly avoiding passing on a grave risk to the other.”   Theologians, AIDS activists and liberal Catholics said the latest developments marked a highly significant, perhaps even historic, change in the Church’s attitude to condoms. “The pope’s statement ... is a startling and welcome shift by the Vatican that has the potential to save tens of thousands of lives,” said Dr. Paul Zeitz, executive director of the Washington-based Global AIDS Alliance (GAA). “The pope has created the possibility of rapid change in the way the Catholic Church views HIV/AIDS and how it can preserve the sanctity of human life,” Zeitz said. Lombardi appeared to take the debate beyond the confines of prostitution in the context of fighting the transmission of AIDS, although the church prefers measures such as abstinence. “The fact that an official Vatican spokesperson seems to be extending the possibility of use clearly is groundbreaking,” said Rev. John T. Pawlikowski, a professor of social ethics at the Catholic Theological Union in Chicago. “The real question is whether this papal statement will impact pastoral activity on the ground, particularly in AIDS-affected regions of the world,” he told Reuters. The church had been saying for decades that condoms were not even part of the solution to fighting AIDS, even though no formal policy on this existed in a Vatican document. The late Cardinal John O’Connor of New York famously branded the use of condoms to stop the spread of AIDS as “The Big Lie.”   “The Vatican’s acknowledgement that Pope Benedict’s acceptance of condom use to prevent the spread of sexually transmitted infections relates to everybody shows how significant the pope’s comments are,” said Jon O’Brien, president of the U.S.-based Catholics for Choice group. In the book, the pope says the use of condoms could be seen as “a first step toward moralization,” even though condoms are “not really the way to deal with the evil of HIV infection.”   Through the book and Lombardi’s comments, the pope seemed to be giving a cautious, qualified endorsement of the “ABC principle” (Abstinence-Be faithful-Condom) espoused by many governments and health organizations in preventing AIDS. Archbishop Rino Fisichella, a Vatican official who presented the book, said Catholics had to “respect” the pope’s words even though they were not made in an official papal pronouncement. “For the first time, the use of condoms in special circumstances was endorsed by the Vatican, and this is good news and a good beginning for us,” said Margaret Chan, director-general of the World Health Organization. Claim: Vatican broadens case for condoms to fight AIDS.


Output: Pope Benedict’s landmark acknowledgement that condoms are sometimes morally justifiable to stop AIDS can apply to anyone — gays, heterosexuals and transsexuals — if that is the only option to avoid transmitting the HIV virus to others, the Vatican said Tuesday.