In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

[Q]: Question: The denaturation of proteins: 
 Options:  <1> It is accompanied by the loss of their activity. <2> It supposes the rupture of peptide bonds. <3> It is always an irreversible process. <4> Alter its primary structure. <5> It is carried out by chaperone proteins.
[A]: 1


[Q]: Question: The hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) by phospholipase C generates the following second messengers: 
 Options:  <1> Inositol 1,4,5-trisphosphate and triacylglycerol. <2> Inositol 1,4, 5-trisphosphate and glycerol. <3> Inositol 1,4, 5-trisphosphate and diacylglycerol. <4> Inositol 4,5-bisphosphate and diacylglycerol. <5> Inositol 4,5-bisphosphate and glycerol.
[A]: 3


[Q]: Question: The paraquat herbicide produces mainly: 
 Options:  <1> Lung damage <2> Hematological abnormalities. <3> Neurotoxicity <4> Ocular toxicity. <5> Ototoxicity
[A]:
1