In this task, you are given a sentence in the Spanish language. Your task is to translate the Spanish sentence into the English language.

Example Input: Los factores de transcripción
Example Output: Transcription factors

Example Input: ¿Qué estudios se deben realizar en un adenocarcinoma con diferenciación mucinosa prominente de colon ascendente diagnosticado en un hombre de 32 años?
Example Output: What studies should be performed in an adenocarcinoma with prominent mucinous differentiation of ascending colon diagnosed in a 32-year-old man?

Example Input: En una determinación de la actividad de un enzima, el agotamiento del sustrato
Example Output:
In a determination of the activity of an enzyme, the depletion of the substrate