Turn the given fact into a question by a simple rearrangement of words. This typically involves replacing some part of the given fact with a WH word. For example, replacing the subject of the provided fact with the word "what" can form a valid question. Don't be creative! You just need to rearrange the words to turn the fact into a question - easy! Don't just randomly remove a word from the given fact to form a question. Remember that your question must evaluate scientific understanding. Pick a word or a phrase in the given fact to be the correct answer, then make the rest of the question. You can also form a question without any WH words. For example, "A radio converts electricity into?"

Fact: The earliest vertebrates were jawless fish.
What were the earliest vertebrates who has relatives today?

Fact: Using gasoline causes global warming.
What causes global warming?

Fact: Sperm and egg nuclei combine to fertilize gametes.

Sperm and egg nuclei combine to do what?