Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Question: Does a null mutation in ANGPTL8 associate with either plasma glucose or type 2 diabetes in humans?
Answer: Disruption of ANGPTL8 function in humans does not seem to have a large effect on measures of glucose tolerance.
no

Question: Do fat mass and obesity-associated gene polymorphisms affect metabolic response to hormone therapy in healthy postmenopausal women?
Answer: The presence of fat mass and obesity-associated gene risk variants in healthy early postmenopausal women does not adversely affect their response to hormone therapy.
no

Question: Does asfotase Alfa Treatment improve Survival for Perinatal and Infantile Hypophosphatasia?
Answer: Asfotase alfa mineralizes the HPP skeleton, including the ribs, and improves respiratory function and survival in life-threatening perinatal and infantile HPP.

yes