Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.

Q: Question: Does triptolide inhibit TGF-β1-induced cell proliferation in rat airway smooth muscle cells by suppressing Smad signaling?
Answer: Triptolide may function as an inhibitor of asthma airway remodeling by suppressing ASMCs proliferation via negative regulation of Smad signaling pathway.

A: yes
****
Q: Question: Is repeated sputum microscopy essential for monitoring tuberculosis treatment response?
Answer: The yield of a second on-the-spot sputum specimen is negligible, provided that the first smear is from an overnight specimen. From the data available, it is evident that repeated follow-up smears are not essential for documenting treatment outcome.

A: no
****
Q: Question: Does mutant GDF15 present a poor prognostic outcome for patients with oral squamous cell carcinoma?
Answer: Patients with missense GDF15 mutations have significantly poorer outcomes than those with wild-type GDF15, missense GDF15 mutations could be used as an independent increased risk factor of poor prognosis in OSCC patients.

A:
yes
****