You will be given a context, a subject and a relation. Your task is to generate a question based on the subject and relation. The generated question should include the given subject. Try to use a minimum number of words that are not present in either context, subject or relation while generating question.
--------
Question: Context : Twofish was designed by Bruce Schneier, John Kelsey, Doug Whiting, David Wagner, Chris Hall, and Niels Ferguson; the ``extended Twofish team'' who met to perform further cryptanalysis of Twofish and other AES contest entrants included Stefan Lucks, Tadayoshi Kohno, and Mike Stay. 
Subject : Twofish 
Relation : based on

Answer: Which is the basis of Twofish?


Question: Context : Irina Kostyuchenkova (Russian: Ирина Костюченкова; born May 11, 1961), is a retired female javelin thrower who represented the Soviet Union and later Ukraine. 
Subject : Irina Kostyuchenkova 
Relation : sex or gender

Answer: What is the sex of Irina Kostyuchenkova?


Question: Context : Nancy Talbot died from complications of Alzheimer's disease on August 30, 2009, at her home in Boulder, Colorado, at the age of 89. 
Subject : Nancy Talbot 
Relation : medical condition

Answer:
What was Nancy Talbot's medical condition near the end of his life?