In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Q: Question: When centrifuging human peripheral blood in a density gradient in Ficoll: 
 Options:  <1> The mononuclear cells float on the Ficoll. <2> The lymphocytes remain in the background. <3> The erythrocytes float on the Ficoll. <4> The granulocytes float on the Ficoll. <5> The monocytes remain in the background.

A: 1
****
Q: Question: The denaturation of proteins: 
 Options:  <1> It is accompanied by the loss of their activity. <2> It supposes the rupture of peptide bonds. <3> It is always an irreversible process. <4> Alter its primary structure. <5> It is carried out by chaperone proteins.

A: 1
****
Q: Question: What is the definition of a fast cycler ?: 
 Options:  <1> The presence of at least four episodes of mood (depressive, manic, or hypomanic) in a period of 12 months. <2> The presence of at least 6 episodes of mood in a period of 6 months. <3> The change from one mood episode to another in a period less than 48 hours. <4> The presence of more than two episodes of mania or hypomania detectable in a month. <5> Patients with Bipolar Disorder I or II with extreme hyperreactivity to minimal stressors.

A:
1
****