Given a passage with a question and an answer to that question, classify if the answer actually answers the question into 'yes' or 'no'. Output 'yes' if the answer answers the question and output 'no' if the answer does not answer the question.
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Question: Question: Does creatine supplementation affect kidney function in an animal model with pre-existing renal failure?
Answer: Creatine supplementation at a dosage of 2% w/w for 4 weeks does not impair kidney function in animals with pre-existing renal failure or in control animals.

Answer: no


Question: Question: Does effective inhibition of nitric oxide production by aminoguanidine reverse hypotension in endotoxaemic rats?
Answer: AG inhibited NO formation in a dose-dependent way. Yet, AG had no haemodynamic effects, suggesting a minor cardiovascular influence of iNOS in this endotoxin model, in parallel to what has been found in microbial sepsis.

Answer: no


Question: Question: Does nebivolol induce parallel improvement of left ventricular filling pressure and coronary flow reserve in uncomplicated arterial hypertension?
Answer: Nebivolol improves LVFP as well as CFR in uncomplicated hypertension. The association between changes of CFR and those of LVFP indicates a possible common denominator between improvement of coronary microvascular function and myocardial stimulation of nitric oxide release induced by the drug.

Answer:
yes