Given a question and a context passage, generate the answer having the word or phrase from the context passage. Here, the answer should be a shortest continous span from the passage.

Input: Consider Input: Context: ESSENTIALS: When high probability of pulmonary embolism (PE), sensitivity of computed tomography (CT) is unclear. We investigated the sensitivity of multidetector CT among 134 patients with a high probability of PE. A normal CT alone may not safely exclude PE in patients with a high clinical pretest probability. In patients with no clear alternative diagnosis after CTPA, further testing should be strongly considered. Whether patients with a negative multidetector computed tomographic pulmonary angiography (CTPA) result and a high clinical pretest probability of pulmonary embolism (PE) should be further investigated is controversial. This was a prospective investigation of the sensitivity of multidetector CTPA among patients with a priori clinical assessment of a high probability of PE according to the Wells criteria. Among patients with a negative CTPA result, the diagnosis of PE required at least one of the following conditions: ventilation/perfusion lung scan showing a high probability of PE in a patient with no history of PE, abnormal findings on venous ultrasonography in a patient without previous deep vein thrombosis at that site, or the occurrence of venous thromboembolism (VTE) in a 3-month follow-up period after anticoagulation was withheld because of a negative multidetector CTPA result. We identified 498 patients with a priori clinical assessment of a high probability of PE and a completed CTPA study. CTPA excluded PE in 134 patients; in these patients, the pooled incidence of VTE was 5.2% (seven of 134 patients; 95% confidence interval [CI] 1.5-9.0). Five patients had VTEs that were confirmed by an additional imaging test despite a negative CTPA result (five of 48 patients; 10.4%; 95% CI 1.8-19.1), and two patients had objectively confirmed VTEs that occurred during clinical follow-up of at least 3 months (two of 86 patients; 2.3%; 95% CI 0-5.5). None of the patients had a fatal PE during follow-up. A normal multidetector CTPA result alone may not safely exclude PE in patients with a high clinical pretest probability. 
 Question: What can be predicted with the Wells criteria?

Output: pulmonary embolism


Input: Consider Input: Context: An electric transformer is a device that uses electromagnetic induction to change the voltage of electric current. Electromagnetic induction is the process of generating current with a magnetic field. It occurs when a magnetic field and electric conductor, such as a coil of wire, move relative to one another. A transformer may either increase or decrease voltage. You can see the basic components of an electric transformer in the Figure 1.1. Click image to the left or use the URL below. URL: The transformer in the diagram consists of two wire coils wrapped around an iron core. Each coil is part of a different circuit. When alternating current passes through coil P, it magnetizes the iron core. Because the current is alternating, the magnetic field of the iron core keeps reversing. This is where electromagnetic induction comes in. The changing magnetic field induces alternating current in coil S of the other circuit. Notice that coil P and coil S in the Figure 1.1 have the same number of turns of wire. In this case, the voltages of the primary and secondary currents are the same. Usually, the two coils of a transformer have different numbers of turns. In that case, the voltages of the two currents are different. When coil S has more turns than coil P, the voltage in the secondary current is greater than the voltage in the primary current (see Figure 1.2). This type of transformer is called a step-up transformer. Thats because it steps up, or increases, the voltage. When coil S has fewer turns of wire than coil P, the voltage in the secondary current is less than the voltage in the primary current (see Figure 1.3). This type of transformer is called a step-down transformer because it steps down, or decreases, the voltage. Q: Both step-up and step-down transformers are used in the electrical grid that carries electricity from a power plant to your home. Where in the grid do you think step-down transformers might be used? A: One place that step-down transformers are used is on the electric poles that supply current to homes. They reduce the voltage of the electric current before it enters home circuits. 
 Question: an electric transformer contains

Output: an iron core.


Input: Consider Input: Context: There has been much debate about the appropriate statistical methodology for the evaluation of malaria field studies and the challenges in interpreting data arising from these trials. The present paper describes, for a pivotal phase III efficacy of the RTS, S/AS01 malaria vaccine, the methods of the statistical analysis and the rationale for their selection. The methods used to estimate efficacy of the primary course of vaccination, and of a booster dose, in preventing clinical episodes of uncomplicated and severe malaria, and to determine the duration of protection, are described. The interpretation of various measures of efficacy in terms of the potential public health impact of the vaccine is discussed. The methodology selected to analyse the clinical trial must be scientifically sound, acceptable to regulatory authorities and meaningful to those responsible for malaria control and public health policy. 
 Question: RTS S AS01 vaccine was developed to prevent which disease?


Output: malaria