In this task, you are given a multiple-choice question about healthcare. Answer the question based on your information and classify your answers into '1', '2', '3', and '4'.

Input: Consider Input: Question: A plasmid contains necessarily: 
 Options:  <1> Genes of resistance to antibiotics. <2> Origin of replication. <3> Integrons <4> Genes of transfer by conjugation. <5> Transposons.

Output: 2


Input: Consider Input: Question: The simultaneous expression of IgM and IgD is observed for the first time in lymphocytes: 
 Options:  <1> Early Pro-B. <2> B mature. <3> Late Pro-B. <4> Pre-B. <5> B immature

Output: 2


Input: Consider Input: Question: The speed of the electron transport chain: 
 Options:  <1> It depends on the concentration of oxygen. <2> Increases when the concentration of ATP increases. <3> It is determined by the need for ATP. <4> It is independent of ADP phosphorylation. <5> It increases when the concentration of NADH and FADH2 rises. 6


Output: 3