GitHub repository: BioMAs/ChemPSy
Primary language: R
Created: 2015-12-01T19:54:31Z
Description: Chemical Prioritization System - ChemPSy  The aim of **ChemPSy** (Chemical Prioritization System) is to develop an innovative approach based on several bioinformatics and biostatistics methodologies to analyze and integrate massive toxicogenomics datasets.   Specific objectives include: (1) classification of chemicals based on transcriptional signatures, e.g. the set of genes whose expression is known to be positively or negatively altered after an exposure to these compounds; (2) the association of classes with human pathologies or deleterious phenotypes, e.g. classes containing toxicants with well-known effects; (3) the prediction of novel reprotoxicants and/or endocrine disruptors based on transcriptional signature similarities with known chemicals affecting testis development and function.