Table:
text: Porphyrin
Biosynthesis
Biosynthesis
Enzyme Location_ Substrate Product Chromosome OMIM Porphyria
ALA synthase Mitochondrion Glycine , succinyl CoA δ-Aminolevulinic acid 3p21.1 125290 none
ALA dehydratase Cytosol δ-Aminolevulinic acid Porphobilinogen 9q34 125270 ALA-Dehydratase deficiency
PBG deaminase Cytosol Porphobilinogen Hydroxymethyl bilane 11q23.3 176000 acute intermittent porphyria
Uroporphyrinogen III synthase Cytosol Hydroxymethyl bilane Uroporphyrinogen III 10q25.2-q26.3 606938 congenital erythropoietic porphyria
Uroporphyrinogen III decarboxylase Cytosol Uroporphyrinogen III Coproporphyrinogen III 1p34 176100 porphyria cutanea tarda
Coproporphyrinogen III oxidase Mitochondrion Coproporphyrinogen III Protoporphyrinogen IX 3q12 121300 coproporphyria
Protoporphyrinogen oxidase Mitochondrion Protoporphyrinogen IX Protoporphyrin IX 1q22 600923 variegate porphyria
Ferrochelatase Mitochondrion Protoporphyrin IX Heme 18q21.3 177000 erythropoietic protoporphyria

Question: Where is the enzyme uroporphyrinogen iii synthase located?

Question: What is the substrate of protoporphyrin ix under porphyrin?

Question: Among porphyrins, which substrate has an OMIM of 176000?