2008 Houston Astros season Game log June

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| June 1 | @ Brewers | 10–1 | Chacón (2–1) | 44613 | 30–28 |
| June 3 | @ Pirates | 2–0 | Dumatrait (2–3) | 13183 | 31–28 |
| June 4 | @ Pirates | 5–2 | Oswalt (4–6) | 9392 | 31–29 |
| June 5 | @ Pirates | 4–3 | Backe (4–7) | 10728 | 31–30 |
| June 6 | Cardinals | 6–1 | Looper (7–5) | 38596 | 32–30 |
| June 7 | Cardinals | 8–4 | Chacón (2–2) | 39811 | 32–31 |
| June 8 | Cardinals | 5–4 | Rodríguez (2–2) | 39923 | 32–32 |
| June 10 | Brewers | 6–1 | McClung (3–3) | 35058 | 33–32 |
| June 11 | Brewers | 10–6 | Backe (4–8) | 33806 | 33–33 |
| June 12 | Brewers | 9–6 | Moehler (3–3) | 35709 | 33–34 |
| June 13 | Yankees † | 2–1 | Brocail (2–1) | 43095 | 33–35 |