49ers–Rams rivalry 2000s (Tied 10-10) 2000s (Tied 10-10)

| Year_ | Date_ | Home_Team | Result_ | Visiting_Team | Venue |
|---|---|---|---|---|---|
| 2008 | November 16 | San Francisco 49ers | 35-16 | St. Louis Rams | Candlestick Park |
| 2008 | December 21 | St. Louis Rams | 16-17 | San Francisco 49ers | Edward Jones Dome |
| 2009 | October 4 | San Francisco 49ers | 35-0 | St. Louis Rams | Candlestick Park |
| 2009 | January 3 | St. Louis Rams | 6-28 | San Francisco 49ers | Edward Jones Dome |