1972 San Diego Chargers season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 1 | September 17, 1972 | at San Francisco 49ers | L 34–3 | 59438 |
| 2 | September 24, 1972 | Denver Broncos | W 37–14 | 49048 |
| 3 | October 1, 1972 | at Oakland Raiders | T 17–17 | 53455 |
| 4 | October 8, 1972 | at Baltimore Colts | W 23–20 | 55459 |
| 5 | October 15, 1972 | at Miami Dolphins | L 24–10 | 80010 |
| 6 | October 22, 1972 | at Detroit Lions | L 34–20 | 54371 |
| 7 | October 29, 1972 | Kansas City Chiefs | L 26–14 | 54533 |
| 8 | November 5, 1972 | Dallas Cowboys | L 34–28 | 54476 |
| 9 | November 13, 1972 | Cleveland Browns | L 21–17 | 54205 |
| 10 | November 19, 1972 | at Kansas City Chiefs | W 27–17 | 79011 |