1961 Detroit Lions season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 1 | September 17, 1961 | at Green Bay Packers | W 17-13 | 32150 |
| 2 | September 24, 1961 | at Baltimore Colts | W 16-15 | 49825 |
| 3 | October 1, 1961 | San Francisco 49ers | L 49-0 | 38065 |
| 4 | October 8, 1961 | Chicago Bears | L 31-17 | 53854 |
| 5 | October 15, 1961 | Los Angeles Rams | W 14-13 | 53295 |
| 6 | October 22, 1961 | Baltimore Colts | L 17-14 | 48447 |
| 7 | October 29, 1961 | at Los Angeles Rams | W 28-10 | 54019 |
| 8 | November 5, 1961 | at San Francisco 49ers | T 20-20 | 46267 |
| 9 | November 12, 1961 | at St. Louis Cardinals | W 45-14 | 54123 |