First appearance First appearances of popular heroes, villains and teams First appearances of popular heroes, villains and teams

| Characters_ | First_Appearance | Cover_Date | Publisher | Estimated_Value |
|---|---|---|---|---|
| Dr. Doom | The Fantastic Four #5 | June 1962 | Marvel Comics | $4,154 |
| Spider-Man | Amazing Fantasy #15 | August 1962 | Marvel Comics | $45,150 |
| Iron Man | Tales of Suspense #39 | March 1963 | Marvel Comics | $3,837 |
| Doctor Strange | Strange Tales #110 | July 1963 | Marvel Comics | $3,500 |
| X-Men ; Magneto | X-Men #1 | September 1963 | Marvel Comics | $13,545 |
| The Avengers | The Avengers #1 | September 1963 | Marvel Comics | $5,148 |
| Daredevil | Daredevil #1 | April 1964 | Marvel Comics | $3,160 |
| Teen Titans | The Brave and the Bold #54 | July 1964 | DC Comics | $415 |
| The Punisher | The Amazing Spider-Man #129 | February 1974 | Marvel Comics | $918 |
| Wolverine | The Incredible Hulk #180 | October 1974 | Marvel Comics | $350 |