2006 Cincinnati Reds season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 14 | @ Cardinals | 1 - 0 | Carpenter (1-1) | 40901 | 7-3 |
| April 15 | @ Cardinals | 9 - 3 | Williams (0-2) | 40752 | 7-4 |
| April 16 | @ Cardinals | 8 - 7 | Weathers (0-1) | 40068 | 7-5 |
| April 17 | Marlins | 9 - 1 | Moehler (0-3) | 16960 | 8-5 |
| April 18 | Marlins | 12 - 6 | Milton (2-1) | 19724 | 8-6 |
| April 19 | Marlins | 9 - 8 | Wellemeyer (0-1) | 18881 | 9-6 |
| April 20 | @ Brewers | 12 - 8 | Lehr (1-1) | 15347 | 10-6 |
| April 21 | @ Brewers | 3 - 1 | Sheets (0-2) | 29825 | 11-6 |
| April 22 | @ Brewers | 11 - 0 | Claussen (1-2) | 35768 | 11-7 |
| April 23 | @ Brewers | 11 - 0 | Davis (0-2) | 29174 | 12-7 |