List of Newcastle Knights records Biggest Losses Biggest Losses

| Margin | Score | Opponent | Venue | Round |
|---|---|---|---|---|
| 65 | 6-71 | Brisbane Broncos | Suncorp Stadium | Rd 11, 2007 |
| 50 | 0-50 | Parramatta Eels | EnergyAustralia Stadium | Rd 14, 2005 |
| 50 | 14-64 | Cronulla-Sutherland Sharks | Toyota Park | Rd 22, 2002 |
| 46 | 6-52 | Melbourne Storm | Olympic Park | Rd 7, 2006 |
| 46 | 6-52 | Bulldogs | Telstra Stadium | Rd 25, 2004 |
| 46 | 2-48 | St. George Illawarra Dragons | WIN Stadium | Rd 4, 2004 |
| 44 | 0-44 | Melbourne Storm | Olympic Park | Rd 18, 2007 |
| 44 | 6-50 | Brisbane Broncos | Sydney Football Stadium | Finals Week 2, 2006 |
| 44 | 4-48 | Sydney Roosters | Sydney Football Stadium | Rd 15, 2004 |
| 42 | 10-52 | New Zealand Warriors | Mt Smart Stadium | Rd 20, 2007 |
| 42 | 0-42 | Auckland Warriors | Mt Smart Stadium | Rd 25, 1999 |