1948 San Francisco 49ers season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Score | Record |
|---|---|---|---|---|---|
| 1 | August 29, 1948 | Buffalo Bills | W | 35-14 | 1-0 |
| 2 | September 5, 1948 | Brooklyn Dodgers | W | 36-20 | 2-0 |
| 3 | September 12, 1948 | New York Yankees | W | 41-0 | 3-0 |
| 4 | September 19, 1948 | Los Angeles Dons | W | 36-14 | 4-0 |
| 5 | September 26, 1948 | at Buffalo Bills | W | 38-28 | 5-0 |
| 6 | October 1, 1948 | at Chicago Rockets | W | 31-14 | 6-0 |
| 7 | October 10, 1948 | at Baltimore Colts | W | 56-14 | 7-0 |
| 8 | October 17, 1948 | at New York Yankees | W | 21-7 | 8-0 |
| 9 | October 24, 1948 | Baltimore Colts | W | 21-10 | 9-0 |
| 10 | November 7, 1948 | Chicago Rockets | W | 44-21 | 10-0 |