2010 US Open (tennis) Singles seeds Men's singles

| Seed | Rank_ | Player | Points | Points_defending | Points_won | New_points | Status_ |
|---|---|---|---|---|---|---|---|
| 10 | 12 | David Ferrer | 3065 | 45 | 180 | 3200 | 4th round lost to Fernando Verdasco [8] |
| 11 | 13 | Marin Čilić | 2855 | 360 | 45 | 2540 | 2nd round lost to Kei Nishikori [Q] |
| 12 | 14 | Mikhail Youzhny | 2620 | 45 | 720 | 3295 | Semifinals lost to Rafael Nadal [1] |
| 13 | 15 | Jürgen Melzer | 2470 | 45 | 180 | 2605 | 4th round lost to Roger Federer [2] |
| 14 | 16 | Nicolás Almagro | 2150 | 90 | 90 | 2150 | 3rd round lost to Sam Querrey [20] |
| 15 | 17 | Ivan Ljubičić | 2120 | 10 | 10 | 2120 | 1st round lost to Ryan Harrison [Q] |
| 16 | 18 | Marcos Baghdatis | 2095 | 75 | 10 | 2030 | 1st round lost to Arnaud Clément |