2005 Washington Nationals season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 26 | Philadelphia Phillies | 3-1 | Lieber (4-1) | 23332 | 11-10 |
| April 27 | Philadelphia Phillies | 0-3 | Loaiza (0-2) | 27483 | 11-11 |
| April 29 | New York Mets | 5-1 | Seo (1-1) | 30627 | 12-11 |
| April 30 | New York Mets | 5-3 | Zambrano (1-3) | 40913 | 13-11 |