1965 American Football League Draft Sixteenth round Sixteenth round

| Pick | Team | Player | Position_ | College |
|---|---|---|---|---|
| 121 | Denver Broncos | Brian Schweda Category:Articles with hCards | Defensive end | Kansas |
| 122 | Houston Oilers | Junior Coffey Category:Articles with hCards | Running back | Washington |
| 123 | Oakland Raiders | Fred Hill Category:Articles with hCards | Tight end | USC |
| 124 | New York Jets | Seth Cartwright Category:Articles with hCards | Defensive tackle | Prairie View A&M |
| 125 | Kansas City Chiefs | Stan Irvine Category:Articles with hCards | Tackle | Colorado |
| 126 | San Diego Chargers | John Godden Category:Articles with hCards | Linebacker | San Diego State |
| 127 | Boston Patriots | George Pyne Category:Articles with hCards | Defensive tackle | Olivet |
| 128 | Buffalo Bills | Bruce Airheart Category:Articles with hCards | Halfback | North Dakota State |