2008 San Diego Padres season Game log May

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| May 1 | @ Phillies | 3–2 | Thatcher (0–3) | 33001 | 11–18 |
| May 2 | @ Marlins | 6–4 | Germano (0–3) | 14562 | 11–19 |
| May 3 | @ Marlins | 7–2 | Nolasco (1–3) | 37689 | 12–19 |
| May 4 | @ Marlins | 10–3 | Maddux (2–3) | 11422 | 12–20 |
| May 6 | @ Braves | 5–3 | Young (2–3) | 21657 | 12–21 |
| May 7 | @ Braves | 5–2 | Wolf (2–2) | 25194 | 12–22 |
| May 8 | @ Braves | 5–4 | Thatcher (0–4) | 28337 | 12–23 |
| May 9 | Rockies | 4–2 | Peavy (4–2) | 31057 | 12–24 |
| May 10 | Rockies | 3–2 | Jiménez (1–3) | 34117 | 13–24 |
| May 11 | Rockies | 6–1 | Reynolds (0–1) | 28624 | 14–24 |
| May 12 | @ Cubs | 12–3 | Wolf (2–3) | 39528 | 14–25 |