2000 St. Louis Rams season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Kickoff | Game_site | Record |
|---|---|---|---|---|---|---|
| 2 | September 10, 2000 | at Seattle Seahawks | W 37-34 | 3:15 p.m. | Husky Stadium | 2-0 |
| 3 | September 17, 2000 | San Francisco 49ers | W 41-24 | 12:00 p.m. | Trans World Dome | 3-0 |
| 4 | September 24, 2000 | at Atlanta Falcons | W 41-20 | 12:00 p.m. | Georgia Dome | 4-0 |
| 5 | October 1, 2000 | San Diego Chargers | W 57-31 | 12:00 p.m | Trans World Dome | 5-0 |
| 6 | Bye | Bye | Bye | Bye | Bye | Bye |
| 7 | October 15, 2000 | Atlanta Falcons | W 45-29 | 12:00 p.m. | Trans World Dome | 6-0 |
| 8 | October 22, 2000 | at Kansas City Chiefs | L 54-34 | 12:00 p.m. | Arrowhead Stadium | 6-1 |
| 9 | October 29, 2000 | at San Francisco 49ers | W 34-24 | 3:15 p.m. | 3Com Park | 7-1 |