2001 Buffalo Bills season NFL Draft NFL Draft

| Round | Pick_ | Player | Position_ | College |
|---|---|---|---|---|
| 1 | 21 | Nate Clements | Cornerback | Ohio State |
| 2 | 46 | Aaron Schobel | Defensive End | TCU |
| 2 | 58 | Travis Henry | Running Back | Tennessee |
| 3 | 76 | Ron Edwards | Defensive Tackle | Texas A&M |
| 3 | 95 | Jonas Jennings | Tackle | Georgia |
| 4 | 110 | Brandon Spoon | Linebacker | North Carolina |
| 5 | 144 | Marques Sullivan | Tackle | Illinois |
| 6 | 178 | Tony Driver | Free Safety | Notre Dame |
| 6 | 195 | Dan O`Leary | Tight End | Notre Dame |
| 6 | 196 | Jimmy R. Williams | Cornerback | Vanderbilt |
| 7 | 214 | Reggie Germany | Wide Receiver | Ohio State |
| 7 | 238 | Tyrone Robertson | Defensive Tackle | Hinds C.C. |