2008 CAF Champions League First Round (1/16 Finals) First Round (1/16 Finals)

| Team_1 | Agg_ | Team_2 | _1st_leg | _2nd_leg |
|---|---|---|---|---|
| Enyimba FC | 7–1 | Simba SC | 4–0 | 3–1 |
| Al-Ahly | 6-0 1 | Al Tahrir | 3-0 | 3-0 |
| Platinum Stars | 3–1 | US Stade Tamponnaise | 2–0 | 1–1 |
| Mamelodi Sundowns | 4–0 | Curepipe Starlight SC | 3–0 | 1–0 |
| Al Hilal | 3–1 | ZESCO United Football Club | 2–0 | 1–1 |