2005–06 Eccellenza season First round First round

| Team_1 | Agg_ | Team_2 | _1st_leg | _2nd_leg |
|---|---|---|---|---|
| Sevegliano (Friuli) | 2–3 | La Nuova Piovese (Veneto A) | 0–1 | 2–2 |
| Corsico (Lombardy A) | 5–2 | Nova Colligiana (Piedmont B) | 2–1 | 3–1 |
| Serenissima (Lombardy C) | 1–6 | Biella L.M. (Piedmont A) | 1–2 | 0–4 |
| Mestre Edo (Veneto B) | 3–4 | Sarzanese (Liguria) | 1–3 | 2–1 |
| Copparese (Emilia Romagna B) | 3–8 | Valle del Giovenco (Abruzzo) | 2–3 | 1–5 |
| Voluntas Osio di Sotto (Lombardy B) | 4–1 | St. Pauls (Trentino-Alto Adige/Südtirol) | 3–1 | 1–0 |
| Terracina (Latium B) | 1–3 | Forte dei Marmi (Tuscany A) | 1–2 | 0–1 |
| Castelnuovese (Tuscany B) | 1–0 | Deruta (Umbria) | 1–0 | 0–0 |
| Formigine (Emilia Romagna A) | 1–3 | Budoni (Sardinia) | 0–0 | 1–3 |
| Civitavecchiese (Latium A) | 3–2 | Montegiorgio (Marche) | 2–1 | 1–1 |