1988 New England Patriots season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Record | Attendance |
|---|---|---|---|---|---|
| 10 | November 6, 1988 | Miami Dolphins | W 21–10 | 5–5 | 60840 |
| 11 | November 13, 1988 | at New York Jets | W 14–13 | 6–5 | 48358 |
| 12 | November 20, 1988 | at Miami Dolphins | W 6–3 | 7–5 | 53526 |
| 13 | November 27, 1988 | at Indianapolis Colts | L 24–21 | 7–6 | 58157 |
| 14 | December 4, 1988 | Seattle Seahawks | W 13–7 | 8–6 | 59086 |
| 15 | December 11, 1988 | Tampa Bay Buccaneers | W 10–7 | 9–6 | 39889 |
| 16 | December 17, 1988 | at Denver Broncos | L 21–10 | 9–7 | 70910 |