2008–09 F.C. Internazionale Milano season Matches Matches

| Date_ | Time_ | Round | Opponent | Ground | Score |
|---|---|---|---|---|---|
| 22 October 2008 | 20:45 CET | Group Stage | Anorthosis | Home | 1–0 |
| 26 October 2008 | 15:00 CET | 08 | Genoa | Home | 0–0 |
| 29 October 2008 | 20:30 CET | 09 | Fiorentina | Away | 0–0 |
| 1 November 2008 | 20:30 CET | 10 | Reggina | Away | 3–2 |
| 4 November 2008 | 20:45 CET | Group Stage | Anorthosis | Away | 3–3 |
| 9 November 2008 | 15:00 CET | 11 | Udinese | Home | 1–0 |
| 15 November 2008 | 20:30 CET | 12 | Palermo | Away | 2–0 |
| 22 November 2008 | 20:30 CET | 13 | Juventus | Home | 1–0 |
| 26 November 2008 | 20:45 CET | Group Stage | Panathinaikos | Home | 0–1 |
| 30 November 2008 | 15:00 CET | 14 | Napoli | Home | 2–1 |
| 6 December 2008 | 20:30 CET | 15 | Lazio | Away | 3–0 |