Swimming at the 2006 Central American and Caribbean Games – Women's 100 metre freestyle Preliminaries Preliminaries

| Rank_ | Swimmer | Country | Time_ | Note_ |
|---|---|---|---|---|
| 1 | Claudia Poll | Costa Rica | 57.43 | Q |
| 2 | Vanessa García | Puerto Rico | 57.95 | Q |
| 3 | Arlene Semeco | Venezuela | 58.11 | Q |
| 4 | Heysi Villarreal | Cuba | 58.67 | Q |
| 5 | Maríana Álvarado | Mexico | 58.69 | Q |
| 6 | Carolina Moreno | Mexico | 59.11 | Q |
| 7 | Isabella Tafur | Colombia | 59.70 | Q |
| 8 | Ximena Maria Vilár | Venezuela | 59.79 | Q |
| 9 | Nikia Hillarie | Bahamas | 59.92 |  |
| 10 | Sharon Fajardo | Honduras | 1:00.45 |  |
| 11 | Maria Álvarez | Colombia | 1:00.76 |  |
| 12 | Alia Atkinson | Jamaica | 1:01.17 |  |
| 13 | Alexis Jordan | Barbados | 1:01.79 |  |
| 14 | Sharntelle McLean | Trinidad and Tobago | 1:03.26 |  |
| 15 | Jennifer Powell | Cayman Islands | 1:03.41 |  |
| 16 | Nishani Cicilson | Suriname | 1:03.88 |  |
| 17 | Sade Daal | Suriname | 1:04.70 |  |