Houston Texans First-round draft picks by year First-round draft picks by year

| Year_ | Pick | Player | Position_ | College |
|---|---|---|---|---|
| 2002 | 1st overall | David Carr | Quarterback | Fresno State |
| 2003 | 3rd overall | Andre Johnson | Wide receiver | Miami (FL) |
| 2004 | 10th overall | Dunta Robinson | Cornerback | South Carolina |
| 2004 | 27th overall (from Tennessee) | Jason Babin * | Defensive end | Western Michigan |
| 2005 | 16th overall (from New Orleans) | Travis Johnson | Defensive tackle | Florida State |
| 2006 | 1st overall | Mario Williams | Defensive end | North Carolina State |
| 2007 | 10th overall (from Atlanta) | Amobi Okoye | Defensive tackle | Louisville |
| 2008 | 26th overall (from Baltimore) | Duane Brown | Offensive tackle | Virginia Tech |
| 2009 | 15th overall | Brian Cushing | Linebacker | Southern California |
| 2010 | 20th overall | Kareem Jackson | Cornerback | Alabama |