1921–22 Toronto St. Patricks season Regular Season Regular Season

| Date_ | Visitor | Score | Home | Record |
|---|---|---|---|---|
| December 17 | Montreal Canadiens | 2–5 | Toronto St. Pats | 1–0–0 |
| December 21 | Toronto St. Pats | 5–4 | Ottawa Senators | 2–0–0 |
| December 24 | Hamilton Tigers | 4–2 | Toronto St. Pats | 2–1–0 |
| December 28 | Toronto St. Pats | 4–3 | Hamilton Tigers | 3–1–0 |
| December 31 | Toronto St. Pats | 3–5 | Montreal Canadiens | 3–2–0 |
| January 4 | Ottawa Senators | 2–3 | Toronto St. Pats | 4–2–0 |
| January 7 | Hamilton Tigers | 2–5 | Toronto St. Pats | 5–2–0 |
| January 11 | Toronto St. Pats | 2–7 | Ottawa Senators | 5–3–0 |
| January 14 | Ottawa Senators | 5–2 | Toronto St. Pats | 5–4–0 |
| January 18 | Toronto St. Pats | 4–9 | Hamilton Tigers | 5–5–0 |
| January 21 | Toronto St. Pats | 5–3 | Montreal Canadiens | 6–5–0 |