1978–79 FA Cup First round proper First round proper

| Tie_no | Home_team | Score | Away_team | Date_ |
|---|---|---|---|---|
| 21 | Hull City | 2–1 | Stafford Rangers | 25 November 1978 |
| 22 | Carlisle United | 1–0 | Halifax Town | 25 November 1978 |
| 23 | Worcester City | 2–0 | Plymouth Argyle | 25 November 1978 |
| 24 | Altrincham | 4–3 | Southport | 25 November 1978 |
| 25 | Southend United | 3–2 | Peterborough United | 25 November 1978 |
| 26 | Exeter City | 1–0 | Brentford | 25 November 1978 |
| 27 | Scunthorpe United | 1–1 | Sheffield Wednesday | 25 November 1978 |
| Replay | Sheffield Wednesday | 1–0 | Scunthorpe United | 28 November 1978 |
| 28 | Mansfield Town | 0–2 | Shrewsbury Town | 25 November 1978 |
| 29 | Wealdstone | 0–5 | Enfield | 25 November 1978 |
| 30 | York City | 1–1 | Blyth Spartans | 25 November 1978 |
| Replay | Blyth Spartans | 3–5 | York City | 28 November 1978 |