DNA glycosylase Types of glycosylases Glycosylases in bacteria, yeast and humans

| E_coli | Yeast_S_cerevisiae | Human | Type_ | Substrates |
|---|---|---|---|---|
| AlkA | Mag1 | MPG | monofunctional | 3-meA, hypoxanthine |
| UDG | Ung1 | UNG | monofunctional | uracil |
| Fpg | Ogg1 | hOGG1 | bifunctional | 8-oxoG, FapyG |
| Nth | Ntg1 | hNTH1 | bifunctional | Tg, hoU, hoC, urea, FapyG |
| Nth | Ntg2 | hNTH1 | bifunctional | Tg, hoU, hoC, urea, FapyG |
| Nei | Not present | hNEIL1 | bifunctional | Tg, hoU, hoC, urea, FapyG, FapyA |
| Nei | Not present | hNEIL2 | bifunctional | AP site, hoU |
| Nei | Not present | hNEIL3 | bifunctional | unknown |
| MutY | Not present | hMYH | monofunctional | A:8-oxoG |
| Not present | Not present | hSMUG1 | monofunctional | U, hoU, hmU, fU |
| Not present | Not present | TDG | monofunctional | T:G mispair |
| Not present | Not present | MBD4 | monofunctional | T:G mispair |