2006–07 EHF Champions League Round of 16 Round of 16

| Team_1 | Agg_ | Team_2 | _1st_leg | _2nd_leg |
|---|---|---|---|---|
| Montpellier HB | 51-54 | FC Barcelona-Cifec | 28-25 | 23-29 |
| MKB Veszprém KC | 60-53 | KIF Kolding Elite A/S | 32-22 | 28-31 |
| RK Gold Club Kozina | 52-70 | Portland San Antonio | 23-34 | 29-36 |
| GOG Svendborg TGI Gudme | 58–64 | BM Ciudad Real | 28–33 | 30–31 |
| SC Pick Szeged | 49–50 | CBM Valladolid | 25–25 | 24–25 |
| Celje | 67–67(a) | SG Flensburg-Handewitt | 41-31 | 26-36 |
| Chekhovskiye Medvedi | 60–69 | VfL Gummersbach | 31-37 | 29-32 |
| Chambéry Savoie HB | 60–76 | THW Kiel | 33–39 | 27–37 |