1990 Indianapolis Colts season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Record | Game_Site | Attendance |
|---|---|---|---|---|---|---|
| 1 | September 9, 1990 | at Buffalo Bills | L 10–26 | 0–1 | Ralph Wilson Stadium | 78899 |
| 2 | September 16, 1990 | New England Patriots | L 14–16 | 0–2 | Hoosier Dome | 49256 |
| 3 | September 23, 1990 | at Houston Oilers | L 10–24 | 0–3 | Astrodome | 50093 |
| 4 | September 30, 1990 | at Philadelphia Eagles | W 24–23 | 1–3 | Veterans Stadium | 62067 |
| 5 | October 7, 1990 | Kansas City Chiefs | W 23–19 | 2–3 | Hoosier Dome | 54950 |
| 6 | Bye | Bye | Bye | Bye | Bye | Bye |
| 7 | October 21, 1990 | Denver Broncos | L 17–24 | 2–4 | Hoosier Dome | 59850 |
| 8 | October 28, 1990 | Miami Dolphins | L 7–27 | 2–5 | Hoosier Dome | 59213 |