2008 Chicago White Sox season Game log September

| Date_ | Opponent | Score | Loss | Time_ | Att_ | Record |
|---|---|---|---|---|---|---|
| September 1 | @ Indians | 0–5 | Richard (2–3) | 2:26 | 23317 | 77–60 |
| September 2 | @ Indians | 3–9 | Danks (10–8) | 3:12 | 20980 | 77–61 |
| September 3 | @ Indians | 4–2 | Sowers (2–8) | 3:12 | 20328 | 78–61 |
| September 5 | Angels | 10–2 | Moseley (1–4) | 2:48 | 32502 | 79–61 |
| September 6 | Angels | 7 – 6 (15) | Speier (1–8) | 3:54 | 31046 | 80–61 |
| September 7 | Angels | 2–3 | H. Ramírez (1–4) | 2:44 | 26029 | 80–62 |
| September 8 | Blue Jays | Postponed (rain), rescheduled for September 9 | Postponed (rain), rescheduled for September 9 | Postponed (rain), rescheduled for September 9 | Postponed (rain), rescheduled for September 9 | Postponed (rain), rescheduled for September 9 |