Jake O'Brien Mixed martial arts record Mixed martial arts record

| Res_ | Record | Opponent | Method_ | Event | Round |
|---|---|---|---|---|---|
| Win | 15–4 | Miodrag Petković | Decision (unanimous) | Flawless Fighting Championship 1: The Beginning | 3 |
| Win | 14–4 | James Shaw | Submission (arm-triangle choke) | Indy MMA | 1 |
| Loss | 13–4 | Gegard Mousasi | Submission (guillotine choke) | Dream 15 | 1 |
| Win | 13–3 | Toni Valtonen | Decision (unanimous) | Fight Festival 27 | 3 |
| Win | 12–3 | Dave Hess | Submission (kimura) | MMA Big Show - Triple Threat | 2 |
| Loss | 11–3 | Jon Jones | Submission (guillotine choke) | UFC 100 | 2 |
| Win | 11–2 | Christian Wellisch | Decision (split) | UFC 94 | 3 |
| Loss | 10–2 | Cain Velasquez | TKO (punches) | UFC: Silva vs. Irvin | 1 |
| Loss | 10–1 | Andrei Arlovski | TKO (punches) | UFC 82 | 2 |