1990 San Francisco 49ers season NFL Draft NFL Draft

| Round_ | Pick_ | Player | Position_ | College |
|---|---|---|---|---|
| 25 | San Francisco 49ers | Dexter Carter | Running Back | Florida State |
| 48 | San Francisco 49ers | Dennis Brown | Defensive End | Washington |
| 54 | San Francisco 49ers | Eric Davis | Cornerback | Jacksonville State |
| 69 | San Francisco 49ers | Ronald Lewis | Wide Receiver | Florida State |
| 93 | San Francisco 49ers | Dean Caliguire | Center | Pittsburgh |
| 166 | San Francisco 49ers | Frank Pollack | Tackle | Northern Arizona |
| 221 | San Francisco 49ers | Dwight Pickens | Wide Receiver | Fresno State |
| 249 | San Francisco 49ers | Odell Haggins | Defensive Tackle | Florida State |
| 277 | San Francisco 49ers | Martin Harrison | Defensive End | Washington |
| 290 | San Francisco 49ers | Anthony Shelton | Safety | Tennessee State |