1980–81 Northern Premier League Final table Final table

| Position_ | Team | Played | Drawn | Lost | Goals_For | Goals_Against | Goal_Difference | Points_1 |
|---|---|---|---|---|---|---|---|---|
| 1 | Runcorn | 42 | 7 | 3 | 99 | 22 | +77 | 71 |
| 2 | Mossley | 42 | 7 | 11 | 95 | 55 | +40 | 55 |
| 3 | Marine | 42 | 10 | 10 | 66 | 41 | +25 | 54 |
| 4 | Buxton | 42 | 7 | 14 | 64 | 50 | +14 | 49 |
| 5 | Gainsborough Trinity | 42 | 13 | 12 | 80 | 57 | +23 | 47 |
| 6 | Burton Albion | 42 | 8 | 15 | 63 | 54 | +9 | 46 |
| 7 | Witton Albion | 42 | 8 | 15 | 70 | 62 | +8 | 46 |
| 8 | Goole Town | 42 | 16 | 12 | 56 | 50 | +6 | 44 |
| 9 | South Liverpool | 42 | 6 | 17 | 59 | 64 | −5 | 44 |
| 10 | Workington | 42 | 13 | 14 | 57 | 48 | +9 | 43 |