2008 New York Yankees season Game log May

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| May 22 | Orioles | 2–1 | Johnson (0–2) | 49452 | 22–25 |
| May 23 | Mariners | 13–2 | Bédard (3–3) | 52005 | 23–25 |
| May 24 | Mariners | 12–6 | Silva (3–4) | 53512 | 24–25 |
| May 25 | Mariners | 6–5 | Putz (1–2) | 54269 | 25–25 |
| May 26 | @ Orioles | 6–1 | Rasner (3–1) | 34928 | 25–26 |
| May 27 | @ Orioles | 10–9 (11) | Hawkins (1–1) | 24030 | 25–27 |
| May 28 | @ Orioles | 4–2 | Guthrie (2–6) | 24791 | 26–27 |
| May 30 | @ Twins | 6–5 | Perkins (2–2) | 30188 | 27–27 |
| May 31 | @ Twins | 7–6 (12) | Rincón (2–2) | 36441 | 28–27 |