2005–06 Mighty Ducks of Anaheim season Regular season October

| Date_ | Opponent | Score | Loss | Attendance | Record | Arena | Points |
|---|---|---|---|---|---|---|---|
| October 5 | @ Blackhawks | 5–3 | Khabibulin (0–1–0) | 16533 | 1–0–0 | United Center | 2 |
| October 8 | @ Predators | 3–2 | Giguere (1–0–1) | 16279 | 1–0–1 | Gaylord Entertainment Center | 3 |
| October 10 | Oilers | 4–2 | Giguere (1–1–1) | 17174 | 1–1–1 | Arrowhead Pond of Anaheim | 3 |
| October 14 | Blue Jackets | 4–3 | Leclaire (0–2–0) | 12930 | 2–1–1 | Arrowhead Pond of Anaheim | 5 |
| October 16 | @ Wild | 4–1 | Giguere (2–2–1) | 18568 | 2–2–1 | Xcel Energy Center | 5 |
| October 19 | @ Blues | 3–2 | Bryzgalov (0–1–0) | 10882 | 2–3–1 | Savvis Center | 5 |
| October 21 | @ Red Wings | 3–2 | Bryzgalov (0–2–0) | 20066 | 2–4–1 | Joe Louis Arena | 5 |