1999–2000 Sheffield Wednesday F.C. season FA Premier League FA Premier League

| Date_ | Opponent | Venue | Result_ | Attendance |
|---|---|---|---|---|
| 11 March 2000 | West Ham United | H | 3-1 | 21147 |
| 18 March 2000 | Watford | A | 0-1 | 15840 |
| 25 March 2000 | Middlesbrough | A | 0-1 | 32748 |
| 5 April 2000 | Aston Villa | H | 0-1 | 18136 |
| 12 April 2000 | Wimbledon | A | 2-0 | 8248 |
| 15 April 2000 | Chelsea | H | 1-0 | 21743 |
| 22 April 2000 | Sunderland | H | 0-2 | 28072 |
| 30 April 2000 | Leeds United | H | 0-3 | 23416 |
| 6 May 2000 | Coventry City | A | 1-4 | 19921 |
| 9 May 2000 | Arsenal | A | 3-3 | 37271 |
| 14 May 2000 | Leicester City | H | 4-0 | 21656 |