2008–09 U.S. Città di Palermo season Competitions Serie A - Matches

| Date_ | Opponent | Venue | Result_ | Scorers | Report_ |
|---|---|---|---|---|---|
| January 18, 2009 - 15:00 | Sampdoria | Home | Won 2–0 | Bresciano (2) | Report |
| January 25, 2009 - 15:00 | Udinese | Home | Won 3–2 | Simplício (2), Cavani | Report |
| January 28, 2009 - 20:30 | AS Roma | Away | Lost 1–2 | Cavani | Report |
| February 1, 2009 - 15:15 | Genoa | Away | Lost 0–1 |  | Report |
| February 8, 2009 - 20:30 | Napoli | Home | Won 2–1 | Migliaccio, Simplício | Report |
| February 15, 2009 - 15:00 | Reggina | Away | Drew 0–0 |  | Report |
| February 21, 2009 - 20:30 | Juventus | Home | Lost 0–2 |  | Report |
| March 1, 2009 - 15:00 | Catania | Home | Lost 0–4 |  | Report |
| March 8, 2009 - 15:00 | Fiorentina | Away | Won 2–0 | Simplício, Miccoli | Report |