2006 Washington Nationals season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 3 | @ New York Mets | 2-3 | Hernández (0-1) | 54371 | 0-1 |
| April 5 | @ New York Mets | 9-5 (10) | Julio (0-1) | 19557 | 1-1 |
| April 6 | @ New York Mets | 5-10 | Ortiz (0-1) | 25839 | 1-2 |
| April 7 | @ Houston Astros | 1-6 | Armas (0-1) | 26978 | 1-3 |
| April 8 | @ Houston Astros | 12-8 | Qualls (0-1) | 39324 | 2-3 |
| April 9 | @ Houston Astros | 3-7 | Drese (0-1) | 31662 | 2-4 |
| April 10 | @ Houston Astros | 4-5 (12) | Stanton (0-1) | 27944 | 2-5 |
| April 11 | New York Mets | 1-7 | Ortiz (0-2) | 40516 | 2-6 |
| April 12 | New York Mets | 1-3 | Armas (0-2) | 29986 | 2-7 |