1963 San Francisco 49ers season Regular season Schedule

| Game | Date_ | Opponent | Result_ | _49ers_points | Opponents | Record | Streak | Attendance |
|---|---|---|---|---|---|---|---|---|
| 1 | September 15 | Minnesota Vikings | L | 20 | 24 | 0-1 | L3 (from 1962 ) | 30781 |
| 2 | September 22 | Baltimore Colts | L | 14 | 20 | 0-2 | L4 (from 1962 ) | 31006 |
| 3 | September 29 | at Minnesota Vikings | L | 14 | 45 | 0-3 | L5 (from ( 1962 ) | 28567 |
| 4 | October 6 | at Detroit Lions | L | 3 | 26 | 0-4 | L6 (from 1962 ) | 44088 |
| 5 | October 13 | at Baltimore Colts | L | 3 | 20 | 0-5 | L7 (from 1962 ) | 56962 |
| 6 | October 20 | Chicago Bears | W | 20 | 14 | 1-5 | W1 | 35837 |
| 7 | October 27 | at Los Angeles Rams | L | 21 | 28 | 1-6 | L1 | 45532 |