1981 VFL season Round 5 Round 5

| Home_team | Home_team_score | Away_team | Away_team_score | Venue | Crowd | Date_ |
|---|---|---|---|---|---|---|
| Hawthorn | 17.16 (118) | North Melbourne | 11.17 (83) | Princes Park | 16106 | 25 April 1981 |
| Collingwood | 21.20 (146) | Melbourne | 13.5 (83) | Victoria Park | 30096 | 25 April 1981 |
| Richmond | 15.22 (112) | Geelong | 11.18 (84) | MCG | 46230 | 25 April 1981 |
| South Melbourne | 18.22 (130) | Footscray | 9.14 (68) | Lake Oval | 12545 | 25 April 1981 |
| St Kilda | 10.13 (73) | Carlton | 19.23 (137) | Moorabbin Oval | 32341 | 25 April 1981 |
| Fitzroy | 19.11 (125) | Essendon | 15.14 (104) | VFL Park | 33465 | 25 April 1981 |