2000 Cleveland Indians season Game log May

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| May 1 | Yankees | 2 - 1 | Wright (2-2) | 42711 | 13-9 |
| May 2 | Yankees | 4 - 2 | Witt (0-1) | 42801 | 13-10 |
| May 3 | Yankees | 6 - 5 | Karsay (0-1) | 42837 | 13-11 |
| May 4 | @ Blue Jays | 8 - 1 | Finley (3-1) | 16637 | 13-12 |
| May 5 | @ Blue Jays | 11 - 10 | Shuey (1-1) | 19191 | 13-13 |
| May 6 | @ Blue Jays | 8 - 6 | Quantrill (0-1) | 23730 | 14-13 |
| May 7 | @ Blue Jays | 10 - 8 (12) | Gunderson (0-1) | 19161 | 15-13 |
| May 8 | @ Twins | 3 - 2 (10) | Wells (0-3) | 7309 | 16-13 |