2008–09 UEFA Champions League First knockout round First knockout round

| Team_1 | Agg_ | Team_2 | _1st_leg | _2nd_leg |
|---|---|---|---|---|
| Chelsea | 3–2 | Juventus | 1–0 | 2–2 |
| Villarreal | 3–2 | Panathinaikos | 1–1 | 2–1 |
| Sporting CP | 1–12 | Bayern Munich | 0–5 | 1–7 |
| Atlético Madrid | 2–2 ( a ) | Porto | 2–2 | 0–0 |
| Lyon | 3–6 | Barcelona | 1–1 | 2–5 |
| Real Madrid | 0–5 | Liverpool | 0–1 | 0–4 |
| Arsenal | 1–1 (7–6 p ) | Roma | 1–0 | 0–1 ( aet ) |
| Internazionale | 0–2 | Manchester United | 0–0 | 0–2 |