2000 New York Giants season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Channel | Attendance |
|---|---|---|---|---|---|
| 10 | November 5, 2000 | at Cleveland Browns | W 24–3 | FOX 1:00 | 72718 |
| 11 | November 12, 2000 | St. Louis Rams | L 24–38 | FOX 1:00 | 78174 |
| 12 | November 19, 2000 | Detroit Lions | L 21–31 | FOX 1:00 | 77897 |
| 13 | November 26, 2000 | at Arizona Cardinals | W 31–7 | ESPN 8:30 | 42094 |
| 14 | December 3, 2000 | at Washington Redskins | W 9–7 | FOX 1:00 | 83485 |
| 15 | December 10, 2000 | Pittsburgh Steelers | W 30–10 | CBS 1:00 | 78164 |
| 16 | December 17, 2000 | at Dallas Cowboys | W 17–13 | ESPN 8:30 | 61311 |
| 17 | December 23, 2000 | Jacksonville Jaguars | W 28–25 | CBS 1:00 | 77924 |