2008 New York Yankees season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 24 | @ White Sox | 7–6 | Chamberlain (1–1) | 27243 | 12–11 |
| April 25 | @ Indians | 6–4 | Pettitte (3–2) | 31467 | 12–12 |
| April 26 | @ Indians | 4–3 | Ohlendorf (0–1) | 35765 | 12–13 |
| April 27 | @ Indians | 1–0 | Sabathia (1–4) | 31598 | 13–13 |
| April 28 | @ Indians | 5–2 | Laffey (0–1) | 20689 | 14–13 |
| April 29 | Tigers | 6–4 | Hughes (0–4) | 49194 | 14–14 |
| April 30 | Tigers | 6–2 | Pettitte (3–3) | 49513 | 14–15 |