List of cities in the Americas by year of foundation List of cities in the Americas by year of foundation List of cities in the Americas by year of foundation

| Year_ | City | State_province_dept_etc_ | Country | Notes_ |
|---|---|---|---|---|
| 1567 | Caracas | Capital District | Venezuela |  |
| 1568 | Mazapil | Zacatecas | Mexico |  |
| 1568 | Goiana | Pernambuco | Brazil | Declared vila in 1685; cidade in 1840. |
| 1568 | Valaparaíso | Zacatecas | Mexico |  |
| 1569 | Santa Ana | Santa Ana | El Salvador | Built over Mayan city of Sihuatehuacán. |
| 1570 | Jerez | Zacatecas | Mexico |  |
| 1570 | Sombrerete | Zacatecas | Mexico |  |
| 1571 | Cochabamba | Cochabamba | Bolivia |  |
| 1572 | Huancavelica | Huancavelica | Peru |  |
| 1573 | San German | Puerto Rico | United States | Second oldest European settlement in Puerto Rico |
| 1573 | Córdoba | Córdoba | Argentina |  |
| 1573 | Santa Fé | Santa Fé | Argentina |  |
| 1574 | Huaraz | Ancash | Peru |  |
| 1574 | Tarija | Tarija Department | Bolivia |  |
| 1575 | Aguascalientes | Aguascalientes | Mexico |  |
| 1576 | León | Guanajuato | Mexico |  |
| 1577 | Juayúa | Sonsonate | El Salvador |  |