1978 Toronto Blue Jays season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 17 | Royals | 3–1 | Jefferson (0–2) | 10169 | 2–7 |
| April 18 | Royals | 5–0 | Lemanczyk (0–3) | 10218 | 2–8 |
| April 19 | Yankees | 4–3 | Gossage (0–3) | 13306 | 3–8 |
| April 20 | Yankees | Postponed (rain) Rescheduled for September 20 | Postponed (rain) Rescheduled for September 20 | Postponed (rain) Rescheduled for September 20 | Postponed (rain) Rescheduled for September 20 |
| April 21 | White Sox | 11–2 | Underwood (0–2) | 10108 | 3–9 |
| April 22 | White Sox | 4–2 | Wood (0–3) | 44327 | 4–9 |
| April 23 | White Sox | 4–0 | Stone (1–1) | 17427 | 5–9 |
| April 24 | Indians | 4–2 | Lemanczyk (0–4) | 10776 | 5–10 |
| April 25 | Indians | 6–5 | Garvin (1–1) | 11348 | 5–11 |
| April 26 | @ Royals | 3–1 | Splittorff (4–1) | 19545 | 6–11 |