2005–06 Sunderland A.F.C. season Premier League Results by matchday

| Date_ | Opponent | Venue | Result_ | Attendance | Scorers_ |
|---|---|---|---|---|---|
| 13 August 2005 | Charlton Athletic | Stadium of Light | 1–3 | 34446 | Gray |
| 20 August 2005 | Liverpool | Anfield | 0–1 | 44913 |  |
| 23 August 2005 | Manchester City | Stadium of Light | 1–2 | 33357 | Le Tallec |
| 27 August 2005 | Wigan Athletic | JJB Stadium | 0–1 | 17223 |  |
| 10 September 2005 | Chelsea | Stamford Bridge | 0–2 | 41969 |  |
| 17 September 2005 | West Bromwich Albion | Stadium of Light | 1–1 | 31657 | Breen |
| 25 September 2005 | Middlesbrough | Riverside Stadium | 2–0 | 29583 | Miller, Arca |
| 1 October 2005 | West Ham United | Stadium of Light | 1–1 | 31212 | Miller |
| 15 October 2005 | Manchester United | Stadium of Light | 1–3 | 39085 | Elliott |