2000 CFL Draft Round six Round six

| Pick_ | CFL_Team | Player | Position_ | School |
|---|---|---|---|---|
| 39 | Saskatchewan Roughriders | Jamie Forsythe | OL | Western Ontario |
| 40 | Winnipeg Blue Bombers | Matthew Sheridan | OL | Manitoba |
| 41 | Edmonton Eskimos | Yves Dossous | LB | Kent State |
| 42 | Toronto Argonauts | Jean-Vincent Posy-Audette | DB | Laval |
| 43 | Montreal Alouettes | Andre Clark | DB | SE Missouri State |
| 44 | BC Lions | Fabian Rayne | RB | Western Ontario |
| 45 | Calgary Stampeders | Brock Balog | DB | Calgary |