2010 NHL Entry Draft Round one Round one

| Pick_ | Player | Nationality | Position_ | NHL_team | Team_from | League_from |
|---|---|---|---|---|---|---|
| 1 | Taylor Hall | Canada | LW | Edmonton Oilers | Windsor Spitfires | Ontario Hockey League |
| 2 | Tyler Seguin | Canada | C | Boston Bruins (from Toronto) 1 | Plymouth Whalers | Ontario Hockey League |
| 3 | Erik Gudbranson | Canada | D | Florida Panthers | Kingston Frontenacs | Ontario Hockey League |
| 4 | Ryan Johansen | Canada | C | Columbus Blue Jackets | Portland Winterhawks | Western Hockey League |
| 5 | Nino Niederreiter | Switzerland | LW | New York Islanders | Portland Winterhawks | Western Hockey League |
| 6 | Brett Connolly | Canada | RW | Tampa Bay Lightning | Prince George Cougars | Western Hockey League |
| 7 | Jeff Skinner | Canada | C | Carolina Hurricanes | Kitchener Rangers | Ontario Hockey League |