List of television show spoofs in Mad 2000s 2000s

| Actual_Title | Writer | Artist | Issue | Date_ |
|---|---|---|---|---|
| Deadwood | Arnie Kogen | Mort Drucker | 452 | April 2005 |
| Desperate Housewives | David Shayne | Mort Drucker | 453 | May 2005 |
| Lost | Dick DeBartolo | Tom Richmond | 453 | May 2005 |
| Medium | Dick DeBartolo | Tom Richmond | 454 | June 2005 |
| Pimp My Ride | Dave Croatto | Tom Richmond | 456 | August 2005 |
| C.S.I: NY | Arnie Kogen | Mort Drucker | 459 | November 2005 |
| Extreme Makeover Home Edition | Dick DeBartolo | Tom Richmond | 460 | December 2005 |
| House | Arnie Kogen | Mort Drucker | 462 | February 2006 |
| Everybody Hates Chris | Arnie Kogen | Tom Richmond | 463 | March 2006 |
| Prison Break | Dick DeBartolo | Mort Drucker | 465 | May 2006 |
| Deal or No Deal? | Dick DeBartolo | Hermann Mejia | 466 | June 2006 |