2005 Colorado Rockies season Game log September

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| September 14 | @ Dodgers | 8–7 | Brazobán (4–9) | 30329 | 59–86 |
| September 16 | @ Diamondbacks | 6–5 | Medders (2–1) | 20207 | 60–86 |
| September 17 | @ Diamondbacks | 6–5 | Williams (3–1) | 24701 | 60–87 |
| September 18 | @ Diamondbacks | 7–1 | Ortiz (5–11) | 24351 | 61–87 |
| September 19 | Padres | 8–7 | Fuentes (2–4) | 18238 | 61–88 |
| September 20 | Padres | 20–1 | Williams (8–12) | 18336 | 62–88 |
| September 21 | Padres | 5–2 | Esposito (0–1) | 18437 | 62–89 |
| September 22 | Padres | 4–2 | Eaton (10–5) | 18119 | 63–89 |
| September 23 | Giants | 7–6 | DeJean (5–4) | 35265 | 63–90 |
| September 24 | Giants | 6–0 | Lowry (13–13) | 25141 | 64–90 |
| September 25 | Giants | 6–2 | Fuentes (2–5) | 31746 | 64–91 |
| September 26 | @ Braves | 6–5 | Reitsma (3–6) | 23788 | 65–91 |