Jorge Santiago Mixed martial arts record Mixed martial arts record

| Res_ | Record | Opponent | Method_ | Event | Round | Time_ | Location_ |
|---|---|---|---|---|---|---|---|
| Loss | 25–12 | Gerald Harris | Decision (unanimous) | WSOF 4 | 3 | 5:00 | Ontario, California , United States |
| Loss | 25–11 | Gunnar Nelson | Decision (unanimous) | UFC on Fuel TV: Barao vs. McDonald | 3 | 5:00 | London, England , United Kingdom |
| Win | 25–10 | Justin Guthrie | Submission (inverted heel hook) | TFC 23 | 1 | 1:34 | Fort Riley, Kansas , United States |
| Win | 24–10 | Leonardo Pecanha | KO (punches) | TFC 21 | 1 | 1:48 | Kansas City, Kansas , United States |
| Loss | 23–10 | Demian Maia | Decision (unanimous) | UFC 136 | 3 | 5:00 | Houston, Texas , United States |
| Loss | 23–9 | Brian Stann | KO (punches) | UFC 130 | 2 | 4:29 | Las Vegas, Nevada , United States |