1990 New England Patriots season Schedule Schedule

| Week | Opponent | Result_ | Stadium | Record | Attendance |
|---|---|---|---|---|---|
| 1 | Miami Dolphins | L 24–27 | Foxboro Stadium | 0–1 | 45305 |
| 2 | at Indianapolis Colts | W 16–14 | Hoosier Dome | 1–1 | 49256 |
| 3 | at Cincinnati Bengals | L 7–41 | Riverfront Stadium | 1–2 | 56470 |
| 4 | New York Jets | L 13–37 | Foxboro Stadium | 1–3 | 36724 |
| 5 | Seattle Seahawks | L 20–33 | Foxboro Stadium | 1–4 | 39735 |
| 6 | Bye | Bye | Bye | Bye | Bye |
| 7 | at Miami Dolphins | L 10–17 | Joe Robbie Stadium | 1–5 | 62630 |
| 8 | Buffalo Bills | L 10–27 | Foxboro Stadium | 1–6 | 51959 |
| 9 | at Philadelphia Eagles | L 20–48 | Veterans Stadium | 1–7 | 65514 |
| 10 | Indianapolis Colts | L 10–13 | Foxboro Stadium | 1–8 | 28924 |