2010 Australian Open Singles seeds Women's singles

| Sd | Player | Points | Points_defending | Points_won | New_points | Status_ |
|---|---|---|---|---|---|---|
| 2 | Dinara Safina | 7600 | 1400 | 280 | 6480 | Retired in 4th round to Maria Kirilenko |
| 3 | Svetlana Kuznetsova | 6081 | 500 | 280 | 5861 | 4th round lost to Nadia Petrova [19] |
| 4 | Caroline Wozniacki | 5785 | 160 | 280 | 5905 | 4th round lost to Li Na [16] |
| 5 | Elena Dementieva | 5505 | 900 | 100 | 4705 | 2nd round lost to Justine Henin [WC] |
| 6 | Venus Williams | 5126 | 100 | 500 | 5526 | Quarterfinal lost to Li Na [16] |
| 7 | Victoria Azarenka | 4740 | 280 | 500 | 4960 | Quarterfinal lost to Serena Williams [1] |
| 8 | Jelena Janković | 3965 | 280 | 160 | 3845 | 3rd round lost to Alyona Bondarenko [31] |