Hainan Airlines destinations Destinations Destinations

| City | Province | Country | IATA | ICAO | Airport |
|---|---|---|---|---|---|
| Quanzhou | Fujian | China | JJN | ZSQZ | Quanzhou Jinjiang Airport |
| Qingyang | Gansu | China | IQN | ZLQY | Qingyang Airport |
| Saint-Petersburg | — | Russia | LED | ULLI | Pulkovo Airport |
| Sanya | Hainan | China | SYX | ZJSY | Sanya Phoenix International Airport |
| Shanghai | Shanghai | China | SHA | ZSPD | Hongqiao International Airport |
| Shanghai | Shanghai | China | PVG | ZSSS | Pudong International Airport |
| Shantou | Guangdong | China | SWA | ZGOW | Chaoshan Airport |
| Shenyang | Liaoning | China | SHE | ZYTX | Taoxian International Airport |
| Shenzhen | Guangdong | China | SZX | ZGSC | Bao`an International Airport |
| Shijiazhuang | Hebei | China | SJW | ZSHC | Shijiazhuang Daguocun International Airport |
| Seattle | — | United States | SEA | KSEA | Seattle-Tacoma International Airport |
| Singapore | — | Singapore | SIN | WSSS | Singapore Changi Airport |
| Sydney | — | Australia | SYD | YSSY | Sydney Airport |