2006 Wilkes-Barre/Scranton Pioneers season Schedule Regular season

| Week | Date_ | Opponent | Result_ | Record | Game_site_ |
|---|---|---|---|---|---|
| 1 | March 31, 2006 | Louisville Fire | W 45–37 | 1–0 | Wachovia Arena |
| 2 | Bye | Bye | Bye | Bye | Bye |
| 3 | April 14, 2006 | Albany Conquest | W 55–48 (OT) | 2–0 | Times Union Center |
| 4 | April 21, 2006 | South Georgia Wildcats | W 36–33 | 3–0 | Wachovia Arena |
| 5 | April 29, 2006 | Manchester Wolves | W 62–47 | 4–0 | Verizon Wireless Arena |
| 6 | May 5, 2006 | Green Bay Blizzard | W 42–27 | 5–0 | Wachovia Arena |
| 7 | May 13, 2006 | Tulsa Talons | L 53–37 | 5–1 | Wachovia Arena |
| 8 | May 20, 2006 | Macon Knights | W 38–22 | 6–1 | Macon Coliseum |
| 9 | May 27, 2006 | Manchester Wolves | L 48–28 | 6–2 | Wachovia Arena |