1999 CFL Draft Round one Round one

| Pick_ | CFL_Team | Player | Position_ | College |
|---|---|---|---|---|
| 1 | BC Lions | Rob Meier | DE | Washington State |
| 2 | Toronto Argonauts | David De La Peralle | OL | Kentucky |
| 3 | BC Lions | Greg Lotysz | OL | North Dakota |
| 4 | Edmonton Eskimos | Trevor Bollers | FB | Iowa |
| 5 | Montreal Alouettes | Sylvain Girard | WR | Concordia |
| 6 | Montreal Alouettes | Davis Sanchez | CB | Oregon |
| 7 | Hamilton Tiger-Cats | Corey Grant | WR | Wilfrid Laurier |