2004 Major League Baseball Draft First round selections First round selections

| Pick | Player | Team | Position_ | School |
|---|---|---|---|---|
| 1 | Matt Bush | San Diego Padres | SS | Mission Bay High School |
| 2 | Justin Verlander | Detroit Tigers | RHP | Old Dominion |
| 3 | Philip Humber | New York Mets | RHP | Rice University |
| 4 | Jeff Niemann | Tampa Bay Devil Rays | RHP | Rice University |
| 5 | Mark Rogers | Milwaukee Brewers | RHP | Mount Ararat High School (ME) |
| 6 | Jeremy Sowers | Cleveland Indians | LHP | Vanderbilt University |
| 7 | Homer Bailey | Cincinnati Reds | RHP | La Grange High School |
| 8 | Wade Townsend | Baltimore Orioles | RHP | Rice University |
| 9 | Chris Nelson | Colorado Rockies | SS | Redan High School |
| 10 | Thomas Diamond | Texas Rangers | RHP | University of New Orleans |