2005 Cleveland Indians season Game log May

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| May 1 | Royals | 6 - 5 | Betancourt (1-1) | 17672 | 9-15 |
| May 3 | @ Twins | 4 - 2 | Mays (1-1) | 16919 | 10-15 |
| May 4 | @ Twins | 5 - 4 | Romero (0-2) | 19856 | 11-15 |
| May 5 | @ Twins | 9 - 0 | Sabathia (2-1) | 18265 | 11-16 |
| May 6 | @ Rangers | 8 - 6 | Astacio (1-4) | 30742 | 12-16 |
| May 7 | @ Rangers | 6 - 1 | Elarton (0-2) | 36311 | 12-17 |
| May 8 | @ Rangers | 7 - 2 | Westbrook (1-6) | 23203 | 12-18 |
| May 9 | @ Angels | 3 - 0 | Lackey (3-2) | 36763 | 13-18 |
| May 10 | @ Angels | 5 - 4 | Sabathia (2-2) | 38320 | 13-19 |