1985 Buffalo Bills season NFL Draft NFL Draft

| Round | Pick | Player | Position_ | School_Club_Team |
|---|---|---|---|---|
| 1 | 1 | Bruce Smith | Defensive End | Virginia Tech |
| 1 | 14 | Derrick Burroughs | Defensive Back | Memphis |
| 2 | 29 | Mark Traynowicz | Guard | Nebraska |
| 2 | 42 | Chris Burkett | Wide Receiver | Jackson State |
| 3 | 57 | Frank Reich | Quarterback | Maryland |
| 3 | 63 | Hal Garner | Linebacker | Utah State |
| 4 | 86 | Andre Reed | Wide Receiver | Kutztown State |
| 4 | 112 | Dale Hellestrae | Tackle | Southern Methodist |
| 5 | 130 | Jimmy Teal | Wide Receiver | Texas A&M |
| 6 | 141 | Mike Hamby | Defensive End | Utah State |
| 7 | 169 | Ron Pitts | Defensive Back | UCLA |
| 8 | 197 | Jacque Robinson | Fullback | Washington |
| 9 | 225 | Glenn Jones | Defensive Back | Norfolk State |
| 10 | 253 | Chris Babyar | Guard | Illinois |