USA Today All-USA high school football team 2011 team First Team Defense

| Player | Position_ | School | Hometown | College |
|---|---|---|---|---|
| Mario Edwards, Jr. | Defensive line | Ryan High School | Denton, Texas | Florida State |
| Ellis McCarthy | Defensive line | Monrovia High School | Monrovia, California | UCLA |
| Noah Spence | Defensive line | Bishop McDevitt High School | Harrisburg, Pennsylvania | Ohio State |
| Tommy Schutt | Defensive line | Glenbard West High School | Glen Ellyn, Illinois | Ohio State |
| Darius Hamilton | Defensive line | Don Bosco Preparatory High School | Ramsey, New Jersey | Rutgers |
| Vince Biegel | Linebacker | Lincoln High School | Wisconsin Rapids, Wisconsin | Wisconsin |
| Scott Starr | Linebacker | Norco High School | Norco, California | Southern California |
| Noor Davis | Linebacker | Lessburg High School | Leesburg, Florida | Stanford |
| Shaq Thompson | Defensive back | Grant Union High School | Sacramento, California | Washington |