1950 San Francisco 49ers season Schedule Schedule

| Date_ | Visitor | Result_ | Score | Home | Record | Attendance |
|---|---|---|---|---|---|---|
| September 17 | New York Yanks | L | 21-17 | San Francisco 49ers | 0-1-0 | 29600 |
| September 24 | Chicago Bears | L | 32-20 | San Francisco 49ers | 0-2-0 | 35558 |
| October 1 | Los Angeles Rams | L | 35-14 | San Francisco 49ers | 0-3-0 | 27262 |
| October 8 | San Francisco 49ers | L | 24-7 | Detroit Lions | 0-4-0 | 17337 |
| October 12 | San Francisco 49ers | L | 29-24 | New York Yanks | 0-5-0 | 5740 |
| October 22 | Detroit Lions | W | 28-27 | San Francisco 49ers | 1-5-0 | 27350 |
| October 29 | Baltimore Colts | W | 17-14 | San Francisco 49ers | 2-5-0 | 14800 |
| November 5 | San Francisco 49ers | L | 28-21 | Los Angeles Rams | 2-6-0 | 15952 |