2000 in film Highest-grossing films Highest-grossing films of 2000

| Rank_ | Title | Studio | Directors | Worldwide_gross |
|---|---|---|---|---|
| 1. | Mission: Impossible II | Paramount Pictures | John Woo | $546,388,105 |
| 2. | Gladiator | DreamWorks | Ridley Scott | $457,640,427 |
| 3. | Cast Away | 20th Century Fox | Robert Zemeckis | $429,632,142 |
| 4. | What Women Want | Paramount Pictures | Nancy Meyers | $374,111,707 |
| 5. | Dinosaur | Walt Disney Pictures | Ralph Zondag and Eric Leighton | $349,822,765 |
| 6. | How the Grinch Stole Christmas | Universal Studios | Ron Howard | $345,141,403 |
| 7. | Meet the Parents | Universal Studios | Jay Roach | $330,444,045 |
| 8. | The Perfect Storm | Warner Bros. | Wolfgang Petersen | $328,718,434 |
| 9. | X-Men | 20th Century Fox | Bryan Singer | $296,339,527 |
| 10. | What Lies Beneath | DreamWorks / 20th Century Fox | Robert Zemeckis | $291,420,351 |