1978 San Diego Chargers season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 11 | November 12, 1978 | Kansas City Chiefs | W 29–23 | 41395 |
| 12 | November 19, 1978 | at Minnesota Vikings | W 13–7 | 38859 |
| 13 | November 26, 1978 | at Kansas City Chiefs | L 23–0 | 26248 |
| 14 | December 4, 1978 | Chicago Bears | W 40–7 | 48492 |
| 15 | December 10, 1978 | Seattle Seahawks | W 37–10 | 49975 |
| 16 | December 17, 1978 | at Houston Oilers | W 45–24 | 49554 |