Charleston Southern Buccaneers Football Charleston Southern vs FBS Schools

| Year_ | FBS_Opponent | Result_ | Opponent_s_Conference | Opponent_s_Head_Coach | Charleston_Southern_s_Head_Coach_ |
|---|---|---|---|---|---|
| 2015 | Alabama Crimson Tide | TBD | SEC | Nick Saban | Jamey Chadwell |
| 2014 | Georgia Bulldogs | TBD | SEC | Mark Richt | Jamey Chadwell |
| 2014 | Vanderbilt Commodores | TBD | SEC | Derek Mason | Jamey Chadwell |
| 2013 | Colorado Buffaloes | L, 43-10 | Pac-12 | Mike MacIntyre | Jamey Chadwell |
| 2012 | Illinois Fighting Illini | L, 44-0 | Big Ten | Tim Beckman | Jay Mills |
| 2011 | UCF Knights | L, 62-0 | C-USA | George O`Leary | Jay Mills |
| 2011 | Florida State Seminoles | L, 62-10 | ACC | Jimbo Fisher | Jay Mills |
| 2010 | Kentucky Wildcats | L, 49-21 | SEC | Joker Phillips | Jay Mills |
| 2010 | Hawaii Warriors | L, 66-7 | WAC | Greg McMackin | Jay Mills |