2006 Washington Nationals season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 13 | New York Mets | 13-4 | Hernández (1-2) | 25460 | 2-8 |
| April 14 | @ Florida Marlins | 3-5 | Drese (0-2) | 12913 | 2-9 |
| April 15 | @ Florida Marlins | 2-1 | Olsen (0-1) | 15668 | 3-9 |
| April 16 | @ Florida Marlins | 7-5 | Herges (0-1) | 10296 | 4-9 |
| April 18 | @ Philadelphia Phillies | 10-3 | Lidle (1-2) | 20072 | 5-9 |
| April 19 | @ Philadelphia Phillies | 6-7 (10) | Stanton (0-2) | 27913 | 5-10 |
| April 20 | @ Philadelphia Phillies | 10-4 | Madson (1-1) | 28177 | 6-10 |
| April 21 | Atlanta Braves | 7-3 | Cormier (0-1) | 24597 | 7-10 |
| April 22 | Atlanta Braves | Postponed (rain) Rescheduled for September 18 | Postponed (rain) Rescheduled for September 18 | Postponed (rain) Rescheduled for September 18 | Postponed (rain) Rescheduled for September 18 |