2004 Boston Red Sox season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 21 | @ Blue Jays | 4 - 2 | Lilly (0-2) | 16163 | 9-5 |
| April 22 | @ Blue Jays | 7 - 3 | Schilling (2-1) | 16480 | 9-6 |
| April 23 | @ Yankees | 11 - 2 | Contreras (0-2) | 55001 | 10-6 |
| April 24 | @ Yankees | 3 - 2 (12) | Quantrill (2-1) | 55195 | 11-6 |
| April 25 | @ Yankees | 2 - 0 | Vázquez (2-2) | 55338 | 12-6 |
| April 27 | Devil Rays | Postponed (rain) Rescheduled for April 29 | Postponed (rain) Rescheduled for April 29 | Postponed (rain) Rescheduled for April 29 | Postponed (rain) Rescheduled for April 29 |
| April 28 | Devil Rays | 6 - 0 | Abbott (2-2) | 35120 | 13-6 |
| April 29 | Devil Rays | 4 - 0 | Zambrano (3-2) | 35614 | 14-6 |