1959 Baltimore Colts season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Record | Game_Site | Attendance |
|---|---|---|---|---|---|---|
| 1 | September 27, 1959 | Detroit Lions | W 21–9 | 1–0 | Memorial Stadium | 55588 |
| 2 | October 3, 1959 | Chicago Bears | L 21–26 | 1–1 | Memorial Stadium | 57557 |
| 3 | October 11, 1959 | at Detroit Lions | W 31–24 | 2–1 | Tiger Stadium | 54197 |
| 4 | October 18, 1959 | at Chicago Bears | W 21–7 | 3–1 | Wrigley Field | 48430 |
| 5 | October 25, 1959 | Green Bay Packers | W 38–21 | 4–1 | Memorial Stadium | 57557 |
| 6 | November 1, 1959 | Cleveland Browns | L 31–38 | 4–2 | Memorial Stadium | 57557 |
| 7 | November 8, 1959 | at Washington Redskins | L 24–27 | 4–3 | Griffith Stadium | 32773 |