Oncogene Classification Classification

| Category | Examples | Cancers | Gene_functions_ |
|---|---|---|---|
| Growth factors, or mitogens | c-Sis | glioblastomas, fibrosarcomas, osteosarcomas, breast carcinomas, and melanomas | induces cell proliferation. |
| Receptor tyrosine kinases | epidermal growth factor receptor (EGFR), platelet-derived growth factor receptor (PDGFR), and vascular endothelial growth factor receptor (VEGFR), HER2/neu | Breast cancer, gastrointestinal stromal tumours, non-small-cell lung cancer and pancreatic cancer | transduce signals for cell growth and differentiation. |