1921 in Brazilian football Campeonato Paulista Campeonato Paulista

| Position_ | Team | Points | Played | Drawn | Lost | Against | Difference |
|---|---|---|---|---|---|---|---|
| 1 | Paulistano | 39 | 22 | 1 | 2 | 14 | 84 |
| 2 | Palestra Itália-SP | 38 | 22 | 0 | 3 | 23 | 58 |
| 3 | Corinthians | 38 | 22 | 2 | 2 | 22 | 57 |
| 4 | AA São Bento | 25 | 22 | 3 | 8 | 41 | 1 |
| 5 | Ypiranga-SP | 22 | 22 | 4 | 9 | 58 | - 23 |
| 6 | Minas Gerais | 21 | 22 | 5 | 9 | 41 | - 2 |
| 7 | Sírio | 20 | 22 | 2 | 11 | 55 | - 15 |
| 8 | Mackenzie - Portuguesa | 17 | 22 | 3 | 12 | 48 | - 23 |
| 9 | AA das Palmeiras | 14 | 22 | 4 | 13 | 40 | - 7 |
| 10 | Santos | 13 | 22 | 3 | 14 | 61 | - 35 |