5th United States Congress Senate Senate

| State_class | Vacator | Reason_for_change | Successor | Date_of_successors_formal_installation |
|---|---|---|---|---|
| Tennessee (1) | Vacant | Tennessee failed to elect a Senator on time | William Cocke ( DR ) | Appointed May 15, 1797 |
| Tennessee (2) | William Blount ( DR ) | Expelled July 8, 1797 | Joseph Anderson ( DR ) | Elected September 26, 1797 |
| Tennessee (1) | William Cocke ( DR ) | Interim appointment until September 26, 1797 | Andrew Jackson ( DR ) | Elected September 26, 1797 |
| Rhode Island (2) | William Bradford ( F ) | Resigned sometime in October, 1797 | Ray Greene ( F ) | Elected November 13, 1797 |