2005 Washington Nationals season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 4 | @ Philadelphia Phillies | 4-8 | Hernández (0-1) | 44080 | 0-1 |
| April 6 | @ Philadelphia Phillies | 7-3 | Worrell (0-1) | 23435 | 1-1 |
| April 7 | @ Philadelphia Phillies | 5-4 (10) | Cormier (0-1) | 21693 | 2-1 |
| April 8 | @ Florida Marlins | 0-9 | Ohka (0-1) | 19327 | 2-2 |
| April 9 | @ Florida Marlins | 3-2 (10) | Alfonseca (0-1) | 30739 | 3-2 |
| April 10 | @ Florida Marlins | 0-8 | Patterson (0-1) | 25089 | 3-3 |
| April 11 | @ Atlanta Braves | 2-11 | Day (0-1) | 16584 | 3-4 |
| April 12 | @ Atlanta Braves | 4-3 | Kolb (0-1) | 20122 | 4-4 |
| April 13 | @ Atlanta Braves | 11-4 | Thomson (1-1) | 19093 | 5-4 |