2006 Colorado Rockies season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 3 | Diamondbacks | 3–2 (11) | Grimsley (0–1) | 47278 | 1–0 |
| April 5 | Diamondbacks | 4–2 | Cook (0–1) | 18553 | 1–1 |
| April 6 | Diamondbacks | 12–5 | Francis (0–1) | 18406 | 1–2 |
| April 7 | @ Padres | 10–4 | Hensley (0–1) | 33918 | 2–2 |
| April 8 | @ Padres | 12–4 | Brazelton (0–1) | 29629 | 3–2 |
| April 9 | @ Padres | 10–4 | Peavy (1–1) | 28901 | 4–2 |
| April 11 | @ Diamondbacks | 6–5 | Hernández (1–1) | 37355 | 5–2 |
| April 12 | @ Diamondbacks | 5–4 | King (0–1) | 18664 | 5–3 |
| April 13 | @ Diamondbacks | 5–3 | Ortiz (0–2) | 18745 | 6–3 |
| April 14 | Phillies | 10–8 | Day (1–1) | 25390 | 6–4 |
| April 15 | Phillies | 10–6 | Lieber (0–3) | 23206 | 7–4 |