1988 NCAA Women's Division I Basketball Tournament First and second rounds First and second rounds

| Region | Host_ | Venue | City | State_ |
|---|---|---|---|---|
| Mideast | Auburn University | Memorial Coliseum (Beard–Eaves–Memorial Coliseum) | Auburn | Alabama |
| Mideast | University of Georgia | Georgia Coliseum (Stegeman Coliseum) | Athens | Georgia |
| Midwest | University of South Carolina | Carolina Coliseum | Columbia | South Carolina |
| Midwest | University of Kansas | Allen Field House | Lawrence | Kansas |
| Midwest | University of Montana | Dahlberg Arena | Missoula | Montana |
| Midwest | University of Texas | Frank Erwin Center | Austin | Texas |
| Midwest | University of Mississippi | Tad Smith Coliseum | University | Mississippi |
| Midwest | Louisiana Tech University | Thomas Assembly Center | Ruston | Louisiana |
| West | Stephen F. Austin University | William R. Johnson Coliseum | Nacogdoches | Texas |
| West | Eastern Illinois University | Lantz Arena | Charleston | Illinois |
| West | University of Iowa | Carver–Hawkeye Arena | Iowa City | Indiana |