1981 New Orleans Saints season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 11 | November 15, 1981 | at Minnesota Vikings | L 20-10 | 45215 |
| 12 | November 22, 1981 | at Houston Oilers | W 27-24 | 49581 |
| 13 | November 29, 1981 | Tampa Bay Buccaneers | L 31-14 | 62209 |
| 14 | December 6, 1981 | at St. Louis Cardinals | L 30-3 | 46923 |
| 15 | December 13, 1981 | Green Bay Packers | L 35-7 | 45518 |
| 16 | December 20, 1981 | San Francisco 49ers | L 21-17 | 43639 |