49ers–Rams rivalry 2000s (Tied 10-10) 2000s (Tied 10-10)

| Year_ | Date_ | Home_Team | Result_ | Visiting_Team | Venue |
|---|---|---|---|---|---|
| 2003 | November 2 | San Francisco 49ers | 30-10 | St. Louis Rams | Candlestick Park |
| 2004 | October 3 | San Francisco 49ers | 14-24 | St. Louis Rams | Candlestick Park |
| 2004 | December 5 | St. Louis Rams | 16-6 | San Francisco 49ers | Edward Jones Dome |
| 2005 | September 11 | San Francisco 49ers | 28-25 | St. Louis Rams | Candlestick Park |
| 2005 | December 24 | St. Louis Rams | 20-24 | San Francisco 49ers | Edward Jones Dome |
| 2006 | September 17 | San Francisco 49ers | 20-13 | St. Louis Rams | Candlestick Park |
| 2006 | November 26 | St. Louis Rams | 20-17 | San Francisco 49ers | Edward Jones Dome |
| 2007 | September 16 | St. Louis Rams | 16-17 | San Francisco 49ers | Edward Jones Dome |
| 2007 | November 18 | San Francisco 49ers | 9-13 | St. Louis Rams | Candlestick Park |