1980 Toronto Blue Jays season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 9 | @ Mariners | 8–6 | Lemanczyk (0–1) | 22588 | 0–1 |
| April 11 | @ Mariners | 10–7 (11) | Dressler (0–1) | 6104 | 1–1 |
| April 12 | @ Mariners | 3–2 (10) | Garvin (0–1) | 6773 | 1–2 |
| April 13 | @ Mariners | 5–1 | Lemanczyk (0–2) | 4567 | 1–3 |
| April 14 | Brewers | Postponed (rain) Rescheduled for July 13 | Postponed (rain) Rescheduled for July 13 | Postponed (rain) Rescheduled for July 13 | Postponed (rain) Rescheduled for July 13 |
| April 16 | Brewers | 11–2 | Slaton (0–1) | 12688 | 2–3 |
| April 17 | Brewers | 1–0 | Sorensen (1–1) | 11235 | 3–3 |
| April 19 | @ Indians | 8–1 | Clancy (0–1) | 61753 | 3–4 |
| April 20 | @ Indians | 5–3 | Denny (0–2) | 11220 | 4–4 |