2011–12 Taça da Liga Second round Second round

| Team_1 | Agg_ | Team_2 | _1st_leg | _2nd_leg_ |
|---|---|---|---|---|
| União da Madeira | 2–5 | Marítimo | 2–3 | 0–2 |
| Penafiel | 2–1 | Académica | 1–1 | 1–0 |
| Santa Clara | 3–2 | União de Leiria | 3–1 | 0–1 |
| Naval | 3–4 | Vitória de Setúbal | 1–2 | 2–2 |
| Moreirense | 4–3 | Beira-Mar | 2–2 | 2–1 |
| Portimonense | 2–2(5–4p) | Feirense | 1–0 | 1–2 |
| Estoril | 4–3 | Olhanense | 4–3 | 0–0 |
| Belenenses | 2–3 | Gil Vicente | 2–1 | 0–2 |