1992 Buffalo Bills season NFL Draft NFL Draft

| Round | Pick | Player | Position_ | College |
|---|---|---|---|---|
| 1 | 27 | John Fina | Tackle | Arizona |
| 3 | 83 | Keith Goganious | Linebacker | Penn State |
| 4 | 111 | Frank Kmet | Defensive end | Purdue |
| 5 | 139 | Matt Darby | Defensive back | UCLA |
| 6 | 167 | Nate Turner | Running back | Nebraska |
| 7 | 195 | Kurt Schulz | Defensive back | Eastern Washington |
| 8 | 223 | Leonard Humphries | Defensive back | Penn State |
| 9 | 251 | Chris Walsh | Wide receiver | Stanford |
| 10 | 279 | Barry Rose | Wide receiver | Wisconsin–Stevens Point |
| 11 | 307 | Vince Marrow | Tight end | Toledo |
| 12 | 335 | Matt Rodgers | Quarterback | Iowa |