1988 San Francisco 49ers season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 10 | November 6, 1988 | at Phoenix Cardinals | L 23-24 | 64544 |
| 11 | November 13, 1988 | Los Angeles Raiders | L 3-9 | 54448 |
| 12 | November 21, 1988 (Mon) | Washington Redskins | W 37-21 | 59268 |
| 13 | November 27, 1988 | at San Diego Chargers | W 48-10 | 51484 |
| 14 | December 4, 1988 | at Atlanta Falcons | W 13-3 | 44048 |
| 15 | December 11, 1988 | New Orleans Saints | W 30-17 | 62977 |
| 16 | December 18, 1988 | Los Angeles Rams | L 16-38 | 62444 |