2006 Roger Federer tennis season Singles: 16 (12–4) Singles: 16 (12–4)

| Outcome | No_ | Date_ | Championship | Surface | Opponent_in_the_final | Score_in_the_final |
|---|---|---|---|---|---|---|
| Runner-up | 13. | June 11, 2006 | French Open , Paris, France | Clay | Rafael Nadal | 6–1, 1–6, 4–6, 6–7 (4–7) |
| Winner | 38. | June 18, 2006 | Halle, Germany (4) | Grass | Tomáš Berdych | 6–0, 6–7 (4–7) , 6–2 |
| Winner | 39. | July 9, 2006 | Wimbledon, London, England, UK (4) | Grass | Rafael Nadal | 6–0, 7–6 (7–5) , 6–7 (2–7) , 6–3 |
| Winner | 41. | September 10, 2006 | US Open, New York City, United States (3) | Hard | Andy Roddick | 6–2, 4–6, 7–5, 6–1 |
| Winner | 42. | October 8, 2006 | Tokyo , Japan | Hard | Tim Henman | 6–3, 6–3 |
| Winner | 43. | October 22, 2006 | Madrid , Spain | Hard (i) | Fernando González | 7–5, 6–1, 6–0 |
| Winner | 44. | October 29, 2006 | Basel, Switzerland | Carpet (i) | Fernando González | 6–3, 6–2, 7–6 (7–3) |