1977–78 Copa del Rey Second round Second round

| Team_1 | Agg_ | Team_2 | _1st_leg | _2nd_leg_ |
|---|---|---|---|---|
| Valladolid Promesas | 1–3 | Elche | 0–2 | 1–1 |
| Peña Sport | 0–4 | Valladolid | 0–2 | 0–2 |
| Algeciras | 2–10 | Real Madrid | 0–6 | 2–4 |
| Real Madrid Castilla | 5–5 (3–4 p) | Sabadell | 4–3 | 1–2 |
| Leganés | 1–5 | Eldense | 1–2 | 0–3 |
| Ciempozuelos | 3–2 | Lleida | 2–1 | 1–1 |
| Alcalá | 1–10 | Valencia | 1–3 | 0–7 |
| Burgos | 4–1 | Huesca | 2–0 | 2–1 |
| Ceuta | 1–6 | Espanyol | 1–1 | 0–5 |
| Atlético Baleares | 2–3 | Cádiz | 1–0 | 1–3 |
| Tudelano | 3–6 | Sporting Gijón | 2–1 | 1–5 |
| Figueres | 3–4 | Racing Santander | 1–2 | 2–2 |
| Carabanchel | 5–2 | Calvo Sotelo | 4–1 | 1–1 |
| Almansa | 1–4 | Rayo Vallecano | 0–2 | 1–2 |
| Osasuna | 4–1 | Guadalajara | 2–0 | 2–1 |
| Deportivo | 5–1 | Plasencia | 3–0 | 2–1 |
| Europa | 3–8 | Málaga | 3–3 | 0–5 |