Indiana State Sycamores football Sycamores in Professional Leagues (50) Sycamores in Professional Leagues (50)

| Player | Class_Year | Position_ | Teams | Career | Highlights |
|---|---|---|---|---|---|
| Tunch Ilkin | 1980 | Offensive Line | Pittsburgh | 1980–1993 | 2x Pro Bowl Lineman |
| Craig Shaffer | 1982 | Line Backer | St. Louis | 1982–1984 | 18 Career Games |
| Wayne Davis | 1985 | Defensive Back | numerous | 1985–1990 | 5 Career INTs |
| Vencie Glenn | 1986 | Defensive Back | numerous | 1986–1995 | 35 Career INTs |
| John Bock | 1994 | Offensive Line | Miami | 1995–2000 | 17 Career Starts |
| Dan Brandenburg | 1996 | Defensive Tackle | Buffalo | 1996–1999 | 42 Career Games |