2004 Chicago White Sox season Game log April

| Date_ | Opponent | Score | Loss | Time_ | Att_ | Record |
|---|---|---|---|---|---|---|
| April 16 | @ Devil Rays | 0–3 | Wright (0–2) | 2:14 | 12108 | 6–4 |
| April 17 | @ Devil Rays | 4–1 | Zambrano (3–1) | 2:39 | 14302 | 7–4 |
| April 18 | @ Devil Rays | 5–0 | González (0–3) | 2:12 | 12072 | 8–4 |
| April 20 | Yankees | 8–11 | Buehrle (1–1) | 3:01 | 32034 | 8–5 |
| April 21 | Yankees | 1–3 | Garland (1–1) | 2:32 | 26154 | 8–6 |
| April 22 | Yankees | 4–3 | Mussina (1–4) | 2:27 | 34030 | 9–6 |
| April 23 | Devil Rays | 3 – 2 (10) | Báez (1–1) | 3:00 | 12049 | 10–6 |
| April 24 | Devil Rays | 1–4 | Wright (0–3) | 2:44 | 17062 | 10–7 |
| April 25 | Devil Rays | 6–5 | Miller (0–1) | 2:43 | 17497 | 11–7 |
| April 27 | Indians | 7 – 11 (10) | Adkins (2–1) | 3:53 | 14572 | 11–8 |