List of number-one singles of 2000 (Canada) RPM Singles Chart: January 2000 - November 2000 RPM Singles Chart: January 2000 - November 2000

| Volume_Issue | Issue_Dates | Weeks_on_Top | Song | Artist |
|---|---|---|---|---|
| 70:21-23 | 27 March - 10 April | 3 |  Never Let You Go  | Third Eye Blind |
| 70:23 | 17 April | 1 |  Maria Maria  | Santana featuring The Product G&B |
| 70:24-25, 71:1-3 | 24 April - 22 May | 5 |  It Feels So Good  | Sonique |
| 71:4-9 | 29 May - 3 July | 6 |  Oops!… I Did It Again  | Britney Spears |
| 71:10-12 | 10 July - 24 July | 3 |  It`s Gonna Be Me  | `N Sync |
| 71:13-14 | 31 July - 7 August | 2 |  Bent  | Matchbox Twenty |
| 71:15 | 14 August | 1 |  Bang Bang Boom  | The Moffatts |
| 71:16-18 | 21 August - 4 September | 3 |  Bent  | Matchbox Twenty |
| 71:19-26 | 11 September - 6 November ‡ | 9 ‡ |  Music  | Madonna |