2009–10 Notre Dame Fighting Irish women's basketball team Schedule Schedule

| Date_ | Location_ | Opponent | Irish_Points | Opp_Points | Record |
|---|---|---|---|---|---|
| 1-4-10 | AWAY | Purdue | 79 | 75 | 13-0 |
| 1-9-10 | HOME | Villanova | 81 | 46 | 14-0 |
| 1-12-10 | HOME | South Florida | 81 | 64 | 15-0 |
| 1-16-10 | AWAY | Connecticut | 46 | 70 | 15-1 |
| 1-19-10 | AWAY | Louisville | 78 | 60 | 16-1 |
| 1-24-10 | HOME | West Virginia | 74 | 66 | 17-1 |
| 1-27-10 | HOME | Providence | 84 | 59 | 18-1 |
| 1-30-10 | AWAY | Syracuse | 74 | 73 | 19-1 |
| 2-1-10 | AWAY | Rutgers | 75 | 63 | 20-1 |
| 2-6-10 | HOME | Pittsburgh | 86 | 76 | 21-1 |
| 2-9-10 | AWAY | Cincinnati | 66 | 50 | 22-1 |
| 2-14-10 | HOME | Depaul | 90 | 66 | 23-1 |
| 2-16-10 | AWAY | St. John`s | 71 | 76 | 23-2 |
| 2-20-10 | AWAY | Georgetown | 66 | 76 | 23-3 |
| 2-23-10 | HOME | Marquette | 82 | 67 | 24-3 |
| 2-27-10 | AWAY | Seton Hall | 72 | 47 | 25-3 |
| 3-1-10 | HOME | Connecticut | 51 | 76 | 25-4 |