2006 Colorado Rockies season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 16 | Phillies | 1–0 | Cook (1–2) | 25144 | 7–5 |
| April 17 | Padres | 5–2 | Francis (0–2) | 18591 | 7–6 |
| April 18 | Padres | 3–2 (11) | Adkins (0–1) | 18595 | 8–6 |
| April 19 | Padres | 13–4 | Day (1–2) | 18827 | 8–7 |
| April 21 | Giants | 9–8 | Worrell (2–1) | 30339 | 9–7 |
| April 22 | Giants | 6–4 | Cook (1–3) | 36035 | 9–8 |
| April 23 | Giants | 3–2 (10) | Fassero (1–1) | 30310 | 10–8 |
| April 24 | @ Phillies | 6–5 | Fogg (2–1) | 20244 | 10–9 |
| April 25 | @ Phillies | 7–6 | Floyd (1–2) | 19512 | 11–9 |
| April 26 | @ Phillies | 9–5 | Jennings (1–1) | 19182 | 11–10 |
| April 27 | @ Phillies | 6–3 | Franklin (1–2) | 21506 | 12–10 |
| April 28 | @ Marlins | 3–2 (10) | Herges (0–2) | 10419 | 13–10 |