2000 New Orleans Saints season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 1 | September 3, 2000 | Detroit Lions | L 14-10 | 64900 |
| 2 | September 10, 2000 | at San Diego Chargers | W 28-27 | 51300 |
| 3 | September 17, 2000 | at Seattle Seahawks | L 20-10 | 59513 |
| 4 | September 24, 2000 | Philadelphia Eagles | L 21-7 | 64900 |
| 5 | Bye | Bye | Bye | Bye |
| 6 | October 8, 2000 | at Chicago Bears | W 31-10 | 66944 |
| 7 | October 15, 2000 | Carolina Panthers | W 24-6 | 50015 |
| 8 | October 22, 2000 | at Atlanta Falcons | W 21-19 | 56508 |
| 9 | October 29, 2000 | at Arizona Cardinals | W 21-10 | 35016 |
| 10 | November 5, 2000 | San Francisco 49ers | W 31-15 | 64900 |