1988 San Diego Chargers season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 11 | November 13, 1988 | at Atlanta Falcons | W 10–7 | 26329 |
| 12 | November 20, 1988 | at Los Angeles Rams | W 38–24 | 45462 |
| 13 | November 27, 1988 | San Francisco 49ers | L 48–10 | 51484 |
| 14 | December 4, 1988 | at Cincinnati Bengals | L 27–10 | 56866 |
| 15 | December 11, 1988 | Pittsburgh Steelers | W 20–14 | 33816 |
| 16 | December 18, 1988 | Kansas City Chiefs | W 24–13 | 26339 |