2008 Chicago White Sox season Game log September

| Date_ | Opponent | Score | Loss | Time_ | Att_ | Record |
|---|---|---|---|---|---|---|
| September 9 | Blue Jays | 1–3 | Vázquez (11–13) | 3:08 | 24621 | 80–63 |
| September 9 | Blue Jays | 2–8 | Richard (2–4) | 2:37 | 28505 | 80–64 |
| September 10 | Blue Jays | 6–5 | Halladay (18–10) | 2:39 | 26198 | 81–64 |
| September 11 | Blue Jays | 4–6 | Floyd (15–7) | 2:57 | 27170 | 81–65 |
| September 12 | Tigers | Postponed (rain) Rescheduled for September 13 | Postponed (rain) Rescheduled for September 13 | Postponed (rain) Rescheduled for September 13 | Postponed (rain) Rescheduled for September 13 | Postponed (rain) Rescheduled for September 13 |
| September 13 | Tigers | Postponed (rain), rescheduled for September 14 | Postponed (rain), rescheduled for September 14 | Postponed (rain), rescheduled for September 14 | Postponed (rain), rescheduled for September 14 | Postponed (rain), rescheduled for September 14 |