1980–81 Aston Villa F.C. season First Division First Division

| Date_ | Opponent | Venue | Result_ | Attendance |
|---|---|---|---|---|
| 16 August 1980 | Leeds United | Elland Road | 2–1 | 23401 |
| 20 August 1980 | Norwich City | Villa Park | 1–0 | 25970 |
| 23 August 1980 | Manchester City | Maine Road | 2–2 | 30017 |
| 30 August 1980 | Coventry City | Villa Park | 1–0 | 26050 |
| 6 September 1980 | Ipswich Town | Portman Road | 0–1 | 23192 |
| 13 September 1980 | Everton | Villa Park | 0–2 | 25673 |
| 20 September 1980 | Wolverhampton Wanderers | Villa Park | 2–1 | 26181 |
| 27 September 1980 | Crystal Palace | Selhurst Park | 1–0 | 18398 |
| 4 October 1980 | Sunderland | Villa Park | 4–0 | 26914 |
| 8 October 1980 | Manchester United | Old Trafford | 3–3 | 38831 |
| 11 October 1980 | Birmingham City | St Andrew`s | 2–1 | 33879 |