List of highway route numbers in Oregon Mainline routes Mainline routes

| Number_ | South_west_end | North_east_end | Formed | Eliminated_ |
|---|---|---|---|---|
| U.S. Route 20 | US 101 in Newport | US 20/US 26 towards Boise, ID | 1940 |  |
| U.S. Route 20 Business | US 20 northwest of Toledo | US 20 northeast of Toledo |  |  |
| U.S. Route 20 Business | US 20/US 97B in Bend | US 20/US 97B in Bend | 1980s |  |
| U.S. Route 26 | US 101 south of Seaside | US 20/US 26 towards Boise, ID | 1952 |  |
| U.S. Route 126 | OR 99 in Eugene | US 26 in Prineville | 1952 | 1972 |
| U.S. Route 28 | OR 99 in Eugene | Former US 30 in Ontario | 1926 | 1952 |
| U.S. Route 30 | US 101 in Astoria | US 30 in Fruitland, ID | 1926 |  |