2005 St. Louis Rams season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 1 | September 11, 2005 | at San Francisco 49ers | L 28-25 | 67918 |
| 2 | September 18, 2005 | at Arizona Cardinals | W 17-12 | 45160 |
| 3 | September 25, 2005 | Tennessee Titans | W 31-27 | 65835 |
| 4 | October 2, 2005 | at New York Giants | L 44-24 | 78453 |
| 5 | October 9, 2005 | Seattle Seahawks | L 37-31 | 65707 |
| 6 | October 17, 2005 | at Indianapolis Colts | L 45-28 | 57307 |
| 7 | October 23, 2005 | New Orleans Saints | W 28-17 | 64586 |
| 8 | October 30, 2005 | Jacksonville Jaguars | W 24-21 | 65251 |
| 9 | Bye | Bye | Bye | Bye |
| 10 | November 13, 2005 | at Seattle Seahawks | L 31-16 | 67192 |