1966 Major League Baseball Draft First round selections First round selections

| Pick | Player | Team | Position_ | Hometown_School |
|---|---|---|---|---|
| 1 | Steve Chilcott | New York Mets | C | Lancaster, CA |
| 2 | Reggie Jackson | Kansas City Athletics | OF | Arizona State |
| 3 | Wayne Twitchell | Houston Astros | RHP | Portland, OR |
| 4 | Ken Brett | Boston Red Sox | LHP | El Segundo, CA |
| 5 | Dean Burk | Chicago Cubs | RHP | Highland, IL |
| 6 | Tom Grieve | Washington Senators | OF | Pittsfield, MA |
| 7 | Leron Lee | St. Louis Cardinals | OF | Sacramento, CA |
| 8 | Jim DeNeff | California Angels | SS | Indiana University |
| 9 | Mike Biko | Philadelphia Phillies | RHP | Dallas, TX |
| 10 | Jim Lyttle | New York Yankees | OF | Florida State |
| 11 | Al Santorini | Milwaukee Braves | RHP | Union, NJ |