Wake Forest Demon Deacons football, 1980–89 Schedule 1980

| Date_ | Opponent | Location_ | Result_ | Attendance |
|---|---|---|---|---|
| 09/06/1980 | Virginia Tech | Groves Stadium • Winston-Salem, NC | L 7-18 | 24500 |
| 09/20/1980 | Citadel | Groves Stadium • Winston-Salem, NC | W 24-7 | 22500 |
| 09/27/1980* | at North Carolina State | Carter-Finley Stadium • Raleigh, NC | W 27-7 | 47800 |
| 10/04/1980 | at William & Mary | Zable Stadium • Williamsburg, VA | W 27-7 | 15800 |
| 10/11/1980* | #8 North Carolina | Groves Stadium • Winston-Salem, NC | L 9-27 | 37411 |
| 10/18/1980* | at Maryland | Byrd Stadium • College Park, MD | L 10-11 | 36472 |
| 10/25/1980* | Virginia | Groves Stadium • Winston-Salem, NC | L 21-24 | 23300 |
| 11/01/1980* | Clemson | Groves Stadium • Winston-Salem, NC | L 33-35 | 28200 |