1968 Boston Patriots season Game-by-game results Game-by-game results

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 1 | September 8, 1968 | at Buffalo Bills | W 16-7 | 38865 |
| 2 | Bye | Bye | Bye | Bye |
| 3 | September 22, 1968 | New York Jets | L 47–31 | 22002 |
| 4 | September 29, 1968 | at Denver Broncos | W 20–17 | 37024 |
| 5 | October 6, 1968 | at Oakland Raiders | L 41–10 | 44253 |
| 6 | October 13, 1968 | Houston Oilers | L 16–0 | 32502 |
| 7 | October 20, 1968 | Buffalo Bills | W 23-6 | 21082 |
| 8 | October 27, 1968 | at New York Jets | L 48-14 | 62351 |
| 9 | November 3, 1968 | Denver Broncos | L 35–14 | 18304 |
| 10 | November 10, 1968 | San Diego Chargers | L 27–17 | 19278 |