USA Today All-USA high school football team 2010 team First Team Offense

| Player | Position_ | School | Hometown | College |
|---|---|---|---|---|
| Kiehl Frazier | Quarterback | Shiloh Christian School | Springdale, Arkansas | Auburn |
| Savon Huggins | Running back | St. Peter`s Prep School | Jersey City, New Jersey | Rutgers |
| Malcolm Brown | Running back | Steele High School | Cibolo, Texas | Texas |
| Jeremy Hill | Running back | Redemptorist High School | Baton Rouge, Louisiana | LSU |
| Demetrius Hart | Running back | Dr. Phillips High School | Orlando, Florida | Alabama |
| Cyrus Kouandjio | Offensive line | DeMatha Catholic High School | Hyattsville, Maryland | Alabama |
| Christian Westerman | Offensive line | Hamilton High School | Chandler, Arizona | Auburn |
| Brandon Shell | Offensive line | Goose Creek High School | Charleston, South Carolina | South Carolina |
| La`el Collins | Offensive line | Redemptorist High School | Baton Rouge, Louisiana | LSU |