1958 San Francisco 49ers season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 1 | September 28, 1958 | Pittsburgh Steelers | W 23–20 | 51856 |
| 2 | October 5, 1958 | Los Angeles Rams | L 33–3 | 59826 |
| 3 | October 12, 1958 | at Chicago Bears | L 28–6 | 45310 |
| 4 | October 19, 1958 | at Philadelphia Eagles | W 30–24 | 33110 |
| 5 | October 26, 1958 | Chicago Bears | L 27–14 | 59441 |
| 6 | November 2, 1958 | Detroit Lions | W 24–21 | 59350 |
| 7 | November 9, 1958 | at Los Angeles Rams | L 56–7 | 95082 |
| 8 | November 16, 1958 | at Detroit Lions | L 35–21 | 54523 |
| 9 | November 23, 1958 | at Green Bay Packers | W 33–12 | 43819 |
| 10 | November 30, 1958 | at Baltimore Colts | L 35–27 | 57557 |