2010–11 UEFA Europa League Knockout phase Round of 16

| Team_1 | Agg_ | Team_2 | _1st_leg | _2nd_leg_ |
|---|---|---|---|---|
| Benfica | 3–2 | Paris Saint-Germain | 2–1 | 1–1 |
| Dynamo Kyiv | 2–1 | Manchester City | 2–0 | 0–1 |
| Twente | 3–2 | Zenit Saint Petersburg | 3–0 | 0–2 |
| CSKA Moscow | 1–3 | Porto | 0–1 | 1–2 |
| PSV Eindhoven | 1–0 | Rangers | 0–0 | 1–0 |
| Bayer Leverkusen | 3–5 | Villarreal | 2–3 | 1–2 |
| Ajax | 0–4 | Spartak Moscow | 0–1 | 0–3 |
| Braga | 1–08 | Liverpool | 1–0 | 0–0 |