1921–22 Toronto St. Patricks season Regular Season Regular Season

| Date_ | Visitor | Score | Home | Record |
|---|---|---|---|---|
| January 25 | Montreal Canadiens | 1–3 | Toronto St. Pats | 7–5–0 |
| January 28 | Ottawa Senators | 2–1 | Toronto St. Pats | 7–6–0 |
| February 1 | Toronto St. Pats | 5–4 | Hamilton Tigers | 8–6–0 |
| February 4 | Montreal Canadiens | 1–3 | Toronto St. Pats | 9–6–0 |
| February 8 | Toronto St. Pats | 4–6 | Montreal Canadiens | 9–7–0 |
| February 11 | Toronto St. Pats | 4–4 | Ottawa Senators | 9–7–1 |
| February 15 | Hamilton Tigers | 4–6 | Toronto St. Pats | 10–7–1 |
| February 18 | Toronto St. Pats | 4–6 | Montreal Canadiens | 10–8–1 |
| February 22 | Toronto St. Pats | 3–4 | Hamilton Tigers | 10–9–1 |
| February 25 | Ottawa Senators | 5–7 | Toronto St. Pats | 11–9–1 |
| March 1 | Toronto St. Pats | 3–2 | Ottawa Senators | 12–9–1 |
| March 4 | Hamilton Tigers | 4–8 | Toronto St. Pats | 13–9–1 |
| March 8 | Montreal Canadiens | 8–7 | Toronto St. Pats | 13–10–1 |