2006 Boston Red Sox season Game log September

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| September 1 | Blue Jays | 2–1 | Lilly (11–12) | 36235 | 73–62 |
| September 2 | Blue Jays | 5–1 | Jarvis (0–1) | 35973 | 73–63 |
| September 3 | Blue Jays | 6–1 | Beckett (14–10) | 35719 | 73–64 |
| September 4 | White Sox | 3–2 | McCarthy (3–6) | 36206 | 74–64 |
| September 5 | White Sox | 1–0 | Vázquez (11–9) | 35912 | 75–64 |
| September 6 | White Sox | 8–1 | Snyder (4–4) | 35923 | 75–65 |
| September 8 | Royals | 10–9 | Timlin (6–5) | 36531 | 75–66 |
| September 9 | Royals | 10–4 | Breslow (0–1) | 36402 | 75–67 |
| September 10 | Royals | 9–3 | Redman (9–9) | 35703 | 76–67 |
| September 12 | @ Orioles | 6–5 | Cabrera (7–10) | 24551 | 77–67 |
| September 13 | @ Orioles | 4–0 | Wakefield (7–9) | 22240 | 77–68 |