1961 Buffalo Bills season Regular season Regular season

| Week | Date_ | Opponent | Result_ | Stadium | Record | Attendance |
|---|---|---|---|---|---|---|
| 8 | October 29, 1961 | Houston Oilers | L 28–16 | War Memorial Stadium | 3–5 | 21237 |
| 9 | November 5, 1961 | Oakland Raiders | L 31–22 | War Memorial Stadium | 3–6 | 17027 |
| 10 | November 12, 1961 | at Dallas Texans | W 30–20 | Cotton Bowl | 4–6 | 15000 |
| 11 | November 19, 1961 | at Denver Broncos | W 23–10 | Bears Stadium | 5–6 | 7645 |
| 12 | November 23, 1961 | at New York Titans | L 21–14 | Polo Grounds | 5–7 | 12023 |
| 13 | December 3, 1961 | at Oakland Raiders | W 26–21 | Candlestick Park | 6–7 | 8011 |