2005 Seattle Mariners season Game log May

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| May 10 | @ Yankees | 7–4 | Sele (2–4) | 39780 | 13–20 |
| May 11 | @ Yankees | 13–9 | Thornton (0–3) | 47844 | 13–21 |
| May 13 | Red Sox | 14–7 | González (1–1) | 44534 | 14–21 |
| May 14 | Red Sox | 6–3 | Villone (0–2) | 46229 | 14–22 |
| May 15 | Red Sox | 5–4 | Wakefield (4–2) | 46145 | 15–22 |
| May 16 | Yankees | 6–3 | Hasegawa (0–1) | 37814 | 15–23 |
| May 17 | Yankees | 6–0 | Mateo (1–1) | 35549 | 15–24 |
| May 18 | Yankees | 7–6 | Gordon (0–3) | 37419 | 16–24 |
| May 20 | Padres | 6–1 | Franklin (2–5) | 38400 | 16–25 |
| May 21 | Padres | 5–3 | Lawrence (2–5) | 37286 | 17–25 |
| May 22 | Padres | 5–0 | Stauffer (1–1) | 41017 | 18–25 |
| May 24 | @ Orioles | 3–2 | Putz (1–1) | 19839 | 18–26 |