1991 New England Patriots season NFL Draft NFL Draft

| Round | Pick | Player | Position_ | School_Club_Team |
|---|---|---|---|---|
| 1 | 11 | Pat Harlow | Offensive tackle | Southern California |
| 1 | 14 | Leonard Russell | Running back | Arizona State |
| 2 | 41 | Jerome Henderson | Defensive back | Clemson |
| 3 | 56 | Calvin Stephens | Guard | South Carolina |
| 4 | 84 | Scott Zolak | Quarterback | Maryland |
| 5 | 112 | Jon Vaughn | Running back | Michigan |
| 5 | 124 | Ben Coates | Tight end | Livingstone |
| 6 | 140 | David Key | Defensive back | Michigan |
| 7 | 168 | Blake Miller | Center | Louisiana State |
| 8 | 196 | Harry Colon | Defensive back | Missouri |
| 9 | 224 | O`Neil Glenn | Guard | Maryland |
| 10 | 251 | Randy Bethel | Tight end | Miami (FL) |
| 11 | 279 | Vince Moore | Wide receiver | Tennessee |
| 11 | 303 | Paul Alsbury | Punter | Texas State |
| 12 | 307 | Tim Edwards | Defensive tackle | Delta State |