1945–46 FA Cup Fifth Round Proper Fifth Round Proper

| Tie_no | Home_team | Score | Away_team | Date_ |
|---|---|---|---|---|
| 1 | Preston North End | 1–1 | Charlton Athletic | 9 February 1946 |
| 1 | Charlton Athletic | 6–0 | Preston North End | 14 February 1946 |
| 1 | Preston North End | 1–6 | Charlton Athletic | Charlton Athletic |
| 2 | Bolton Wanderers | 1–0 | Middlesbrough | 9 February 1946 |
| 2 | Middlesbrough | 1–1 | Bolton Wanderers | 13 February 1946 |
| 2 | Bolton Wanderers | 2–1 | Middlesbrough | Middlesbrough |
| 3 | Sunderland | 1–0 | Birmingham City | 9 February 1946 |
| 3 | Birmingham City | 3–1 | Sunderland | 13 February 1946 |
| 3 | Sunderland | 2–3 | Birmingham City | Birmingham City |
| 4 | Queens Park Rangers | 1–3 | Brentford | 9 February 1946 |
| 4 | Brentford | 0–0 | Queens Park Rangers | 14 February 1946 |
| 4 | Queens Park Rangers | 1–3 | Brentford | Brentford |