2005–06 Eccellenza season First round First round

| Team_1 | Agg_ | Team_2 | _1st_leg | _2nd_leg |
|---|---|---|---|---|
| Akragas (Sicily B) | 0–4 | Fasano (Apulia) | 0–1 | 0–3 |
| Agnonese (Molise) | 3–6 | Acicatena (Sicily A) | 2–3 | 1–3 |
| Gragnano (Campania B) | 5–2 | Internapoli (Campania B) | 2–0 | 3–2 |
| Castrovillari (Calabria) | 2–1 | Avigliano (Basilicata) | 1–0 | 1–1 |