2010 Southeastern Conference football season Week Two Week Two

| Date_ | Time_ | Visiting_team | Home_team | Site | Broadcast | Result_ | Attendance |
|---|---|---|---|---|---|---|---|
| September 11 | 7:00pm | Louisiana-Monroe | #14 Arkansas | War Memorial Stadium • Little Rock, AR | FSN | W 31–7 | 55705 |
| September 11 | 7:00pm | #7 Oregon | Tennessee | Neyland Stadium • Knoxville, TN | ESPN2 | L 48–13 | 102035 |
| September 11 | 7:30pm | Western Kentucky | Kentucky | Commonwealth Stadium • Lexington, KY | CSS | W 63–28 | 66584 |