List of U.S. Highways in Michigan Former mainline highways Former mainline highways

| South_or_west_terminus | North_or_east_terminus | First_year | Final_year | Notes |
|---|---|---|---|---|
| Muskegon | Detroit | 1926 | 1962 | Replaced by I-96 |
| Erie | Port Austin | 1926 | 1973 | Replaced by I-75 and M-25 |
| Coldwater | Mackinaw City | 1926 | 2002 | Replaced by I-69 and US127 |
| Niles | Hagar Shores | 1937 | 1998 | Replaced by US31 and M-63 |
| Crystal Falls | Covington | 1926 | 1928 | Replaced by US 141 |
| New Buffalo | Detroit | 1926 | 1961 | Replaced by US 12 when I-94 replaced US 12 |
| Indiana state line | Union | 1926 | 1935 | Replaced by M-205 , now a county road |