2008 Minnesota Twins season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 10 | @ White Sox | Postponed (rain) Rescheduled for June 9 | Postponed (rain) Rescheduled for June 9 | Postponed (rain) Rescheduled for June 9 | Postponed (rain) Rescheduled for June 9 |
| April 11 | @ Royals | 5 - 0 | Meche (0-2) | 16691 | 5-5 |
| April 12 | @ Royals | 2 - 0 | Tomko (1-1) | 36300 | 6-5 |
| April 13 | @ Royals | 5 - 1 | Liriano (0-1) | 13886 | 6-6 |
| April 14 | @ Tigers | 11 - 9 | Neshek (0-1) | 32002 | 6-7 |
| April 15 | @ Tigers | 6 - 5 | Crain (0-1) | 30901 | 6-8 |
| April 16 | Rays | 6 - 5 | Wheeler (0-2) | 20209 | 7-8 |
| April 17 | Rays | 7 - 3 | Bonser (1-3) | 14781 | 7-9 |
| April 18 | Indians | 4 - 0 | Liriano (0-2) | 22366 | 7-10 |
| April 19 | Indians | 3 - 0 | Westbrook (1-2) | 34210 | 8-10 |