2005 Chicago White Sox season Game log May

| Date_ | Opponent | Score | Loss | Time_ | Att_ | Record |
|---|---|---|---|---|---|---|
| May 1 | Tigers | 8–0 | Ledezma (1–2) | 2:23 | 20862 | 18–7 |
| May 3 | Royals | 5–4 | Sisco (0–1) | 2:13 | 12362 | 19–7 |
| May 4 | Royals | 4–2 | Hernández (1–4) | 2:39 | 12712 | 20–7 |
| May 5 | Royals | 2–1 | Greinke (0–3) | 2:10 | 15389 | 21–7 |
| May 6 | @ Blue Jays | 5–3 | Frasor (1–2) | 3:03 | 21769 | 22–7 |
| May 7 | @ Blue Jays | 10–7 | Lilly (1–3) | 2:51 | 23078 | 23–7 |
| May 8 | @ Blue Jays | 5–4 | Chacin (4–2) | 2:38 | 20946 | 24–7 |
| May 9 | @ Devil Rays | 2–4 | García (3–2) | 2:45 | 8774 | 24–8 |
| May 10 | @ Devil Rays | 6–7 | Takatsu (0–2) | 3:17 | 9389 | 24–9 |