1980 San Diego Chargers season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 11 | November 16, 1980 | Kansas City Chiefs | W 20-7 | 50248 |
| 12 | November 20, 1980 | at Miami Dolphins | W 27-24 | 63013 |
| 13 | November 30, 1980 | Philadelphia Eagles | W 22-21 | 51567 |
| 14 | December 7, 1980 | at Washington Redskins | L 40-17 | 48556 |
| 15 | December 13, 1980 | Seattle Seahawks | W 21-14 | 49980 |
| 16 | December 22, 1980 | Pittsburgh Steelers | W 26-17 | 51785 |