1980 Toronto Blue Jays season Game log September

| Date_ | Opponent | Score | Loss | Record |
|---|---|---|---|---|
| September 14 | Orioles | 4–3 (13) | Martínez (5–4) | 61–82 |
| September 16 | @ Yankees | 5–4 | Clancy (13–13) | 61–83 |
| September 17 | @ Yankees | 8–7 (13) ‡ | Kucek (3–7) | 61–84 |
| September 18 | @ Yankees | 2–1 | John (21–8) | 62–84 |
| September 19 | @ Orioles | 8–6 (12) | Willis (1–1) | 62–85 |
| September 20 | @ Orioles | 6–1 | Stieb (12–13) | 62–86 |
| September 21 | @ Orioles | 2–1 | Clancy (13–14) | 62–87 |
| September 22 | @ Tigers | 6–5 | Weaver (2–3) | 63–87 |
| September 23 | @ Tigers | 9–7 | Rozema (6–9) | 64–87 |
| September 24 | @ Tigers | 9–8 (10) | Kucek (3–8) | 64–88 |
| September 26 | Red Sox | 3–1 | Stieb (12–14) | 64–89 |
| September 27 | Red Sox | 4–3 | Clancy (13–15) | 64–90 |
| September 28 | Red Sox | 7–3 | McLaughlin (6–9) | 64–91 |