2008 AFL season Round 21 Round 21

| Home_team | Home_team_score | Away_team | Away_team_score | Ground | Crowd | Date_ | Report |
|---|---|---|---|---|---|---|---|
| Western Bulldogs | 23.13 (151) | Essendon | 15.15 (105) | Telstra Dome | 37294 | Friday, 22 August | AFL.com.au |
| Richmond | 15.15 (105) | Fremantle | 15.8 (98) | MCG | 24881 | Saturday, 23 August | AFL.com.au |
| Port Adelaide | 18.21 (129) | Melbourne | 7.9 (51) | AAMI Stadium | 18875 | Saturday, 23 August | AFL.com.au |
| Brisbane Lions | 16.13 (109) | Carlton | 18.7 (115) | The Gabba | 34327 | Saturday, 23 August | AFL.com.au |
| Collingwood | 18.10 (118) | Sydney | 10.13 (73) | Telstra Dome | 45507 | Saturday, 23 August | AFL.com.au |
| Geelong | 17.13 (115) | North Melbourne | 13.4 (82) | Skilled Stadium | 24288 | Sunday, 24 August | AFL.com.au |
| St Kilda | 13.17 (95) | Adelaide | 6.11 (47) | Telstra Dome | 33811 | Sunday, 24 August | AFL.com.au |
| West Coast | 9.8 (62) | Hawthorn | 19.19 (133) | Subiaco | 37040 | Sunday, 24 August | AFL.com.au |