List of Ottawa Senators draft picks 2000 draft picks 2000 draft picks

| Round | Overall | Player | Nationality | Club_team |
|---|---|---|---|---|
| 1 | 21 | Anton Volchenkov | Russia | Krylja Sovetov (Moscow, Russia) |
| 2 | 45 | Mathieu Chouinard | Canada | Shawinigan Cataractes (QMJHL) |
| 2 | 55 | Antoine Vermette | Canada | Victoriaville Tigres (QMJHL) |
| 3 | 87 | Jan Bohac | Czech Republic | HC Slavia Praha (Prague, Czech Republic) |
| 4 | 122 | Derrick Byfuglien | United States | Fargo-Moorhead Ice Sharks (USHL) |
| 5 | 156 | Greg Zanon | Canada | University of Nebraska-Omaha (NCAA) |
| 5 | 157 | Grant Potulny | United States | Lincoln Stars (USHL) |
| 5 | 158 | Sean Connolly | United States | Marquette Northern Michigan University (NCAA) |
| 6 | 188 | Jason Maleyko | Canada | Brampton Battalion (OHL) |
| 9 | 283 | James DeMone | Canada | Portland Winterhawks (WHL) |