List of Playboy Cyber Girls of the Week 2010 2010

| Week_1 | Week_2 | Week_3 | Week_4 | Week_5 |
|---|---|---|---|---|
| Karlee Rose | Jason Hibbert | Shelly Louise | Deanna Murphy | [Month Ended] |
| Ryan Leigh | Kamila Sulewska | Candace Rae | Bethanie Badertscher ** | [Month Ended] |
| Chelsea Grimland | Jessica Sutherland | Ariana Diabla | Elle Smith | Elizabeth Mendez* |
| Jamie Bradford* | Jillian Kaye | Tiffany Schlumbrecht | Bree Morgan | [Month Ended] |
| Megan Medellin | Tali De`Mar | Ava Hart | Brandi Bryant* | Amy Varela |
| Jesse Lunderby* | Jengie Beverly Zaccheo | Samantha Buxton | Cassandra Dawn | [Month Ended] |
| Holly Jo | Victoria Nicole | Reby Sky * | Jessica King | [Month Ended] |
| Amber Kyler | Alexandra Rae | Jelena Timofejeva | Erika Mayshawn | Brittany Barbour* |
| Jessica Gamboa* | Angela Marie | Titania Lyn | Rachel Lorraine | [Month Ended] |