2005 Buffalo Bills season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 11 | November 20, 2005 | at San Diego Chargers | L 48–10 | 65602 |
| 12 | November 27, 2005 | Carolina Panthers | L 13–9 | 71440 |
| 13 | December 4, 2005 | at Miami Dolphins | L 24–23 | 72051 |
| 14 | December 11, 2005 | New England Patriots | L 35–7 | 71810 |
| 15 | December 17, 2005 | Denver Broncos | L 28–17 | 71887 |
| 16 | December 24, 2005 | at Cincinnati Bengals | W 37–27 | 65485 |
| 17 | January 1, 2006 | at New York Jets | L 30–26 | 76822 |