2009 Big Ten Conference football season 2010 NFL Draft 2010 NFL Draft

| Round_ | Pick_ | NFL_Team | Player | Position_ | College |
|---|---|---|---|---|---|
| 5 | 144 | Houston Texans (from Carolina via Kansas City) | Sherrick McManis | Cornerback | Northwestern |
| 5 | 150 | New England Patriots (from Houston) | Zoltan Mesko | Punter | Michigan |
| 5 | 154 | Green Bay Packers | Andrew Quarless | Tight end | Penn State |
| 5 | 167 | Minnesota Vikings | Nathan Triplett | Linebacker | Minnesota |
| 7 | 214 | Minnesota Vikings (from Cleveland via Detroit) | Mickey Shuler, Jr. | Tight end | Penn State |
| 7 | 215 | Oakland Raiders | Jeremy Ware | Cornerback | Michigan State |
| 7 | 216 | Buffalo Bills | Kyle Calloway | Offensive tackle | Iowa |
| 7 | 232 | Denver Broncos (from Baltimore via Tampa Bay) | Jammie Kirlew | Defensive end | Indiana |
| 7 | 242 | Pittsburgh Steelers | Doug Worthington | Defensive end | Ohio State |
| 7 | 244 | Philadelphia Eagles | Kurt Coleman | Safety | Ohio State |