2010–11 Segunda División Managerial changes Managerial changes

| Team | Outgoing_manager | Manner_of_departure | Date_of_vacancy | Replaced_by | Date_of_appointment | Position_in_table |
|---|---|---|---|---|---|---|
| Valladolid | Javier Torres Gómez | End of tenure as caretaker | 6 December 2010 | Abel Resino | 6 December 2010 | 6th |
| Ponferradina | José Carlos Granero | Sacked | 4 January 2011 | Tomás Nistal (as caretaker) | 4 January 2011 | 20th |
| Ponferradina | Tomás Nistal | End of tenure as caretaker | 16 January 2011 | Claudio Barragán | 17 January 2011 | 21st |
| Tenerife | Juan Carlos Mandiá | Sacked | 23 January 2011 | Antonio Tapia | 24 January 2011 | 22nd |
| Albacete | Antonio Calderón | Sacked | 13 February 2011 | David Vidal | 13 February 2011 | 19th |
| Salamanca | Óscar Cano | Sacked | 14 February 2011 | Pepe Murcia | 15 February 2011 | 19th |
| Las Palmas | Paco Jémez | Sacked | 26 February 2011 | Juan Manuel Rodríguez | 26 February 2011 | 18th |