2010 NHL Entry Draft Round two Round two

| Pick_ | Player | Nationality | Position_ | Team_from | League_from |
|---|---|---|---|---|---|
| 50 | Connor Brickley | United States | C | Des Moines Buccaneers | United States Hockey League |
| 51 | Calle Jarnkrok | Sweden | C | Brynäs IF | Elitserien (Sweden) |
| 52 | Philip Lane | United States | RW | Brampton Battalion | Ontario Hockey League |
| 53 | Mark Alt | United States | D | Cretin-Derham Hall | United States High School-MN |
| 54 | Justin Holl | United States | D | Omaha Lancers | United States Hockey League |
| 55 | Petr Straka | Czech Republic | F | Rimouski Océanic | Quebec Major Junior Hockey League |
| 56 | Johan Larsson | Sweden | C | Brynäs IF | J20 SuperElit (Sweden) |
| 57 | Oscar Lindberg | Sweden | C | Skellefteå AIK | Elitserien (Sweden) |
| 58 | Kent Simpson | Canada | G | Everett Silvertips | Western Hockey League |
| 59 | Jason Zucker | United States | RW | U.S. National U-18 Team | United States Hockey League |
| 60 | Stephen Johns | United States | D | U.S. National U-18 Team | United States Hockey League |