2010–11 Buffalo Sabres season Game log December

| Game | December | Opponent | Score | Decision | Location_Attendance | Record |
|---|---|---|---|---|---|---|
| 26 | 3 | Columbus Blue Jackets | 5-0 | Miller | HSBC Arena/18,529 | 10-13-3 |
| 27 | 4 | @ Ottawa Senators | 1-0 (SO) | Miller | Scotiabank Place/16,364 | 11-13-3 |
| 28 | 7 | @ Boston Bruins | 2-3 (OT) | Miller | TD Garden/17,565 | 11-13-4 |
| 29 | 9 | San Jose Sharks | 6-3 | Miller | HSBC Arena/18,017 | 12-13-4 |
| 30 | 11 | Pittsburgh Penguins | 2-5 | Miller | HSBC Arena/18,690 | 12-14-4 |
| 31 | 15 | Boston Bruins | 3-2 | Miller | HSBC Arena/18,197 | 13-14-4 |
| 32 | 17 | @ Florida Panthers | 2-6 | Miller | BankAtlantic Center/16,894 | 13-15-4 |
| 33 | 18 | @ Tampa Bay Lightning | 1-3 | Miller | St. Pete Times Forum/17,141 | 13-16-4 |
| 34 | 21 | Mighty Ducks of Anaheim | 5-2 | Miller | HSBC Arena/18,690 | 14-16-4 |