1965 Denver Broncos season Regular season Regular season

| Week | Date_ | Opponent | Result_ | Game_site | Record | Attendance |
|---|---|---|---|---|---|---|
| 1 | September 11, 1965 | at San Diego Chargers | L 31–34 | Balboa Stadium | 0–1 | 27022 |
| 2 | September 19, 1965 | Buffalo Bills | L 15–30 | Bears Stadium | 0–2 | 30682 |
| 3 | September 24, 1965 | at Boston Patriots | W 27–10 | Fenway Park | 1–2 | 26782 |
| 4 | October 3, 1965 | New York Jets | W 16–13 | Bears Stadium | 2–2 | 34988 |
| 5 | October 10, 1965 | Kansas City Chiefs | L 23–31 | Bears Stadium | 2–3 | 31001 |
| 6 | October 17, 1965 | Houston Oilers | W 28–17 | Bears Stadium | 3–3 | 32492 |
| 7 | October 24, 1965 | at Buffalo Bills | L 13–31 | War Memorial Stadium | 3–4 | 45046 |