SouthEastern Lacrosse Conference Division I Division I

| Institution | Location_ | Founded | Affiliation | Enrollment | Team_Nickname | Primary_conference |
|---|---|---|---|---|---|---|
| University of South Florida | Tampa, Florida | 1801 | Public | 47122 | Bulls | Big East ( Division I ) |
| University of Tennessee | Knoxville, Tennessee | 1794 | Public | 27107 | Volunteers | SEC ( Division I ) |
| Vanderbilt University | Nashville, Tennessee | 1873 | Private/Non-sectarian | 12514 | Commodores | SEC ( Division I ) |
| Wake Forest University | Winston-Salem, North Carolina | 1834 | Private/Non-sectarian | 6862 | Demon Deacons | ACC ( Division I ) |