2008 Minnesota Twins season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| March 31 | Angels | 3 - 2 | Weaver (0-1) | 49596 | 1-0 |
| April 1 | Angels | 9 - 1 | Bonser (0-1) | 24586 | 1-1 |
| April 2 | Angels | 1 - 0 | Blackburn (0-1) | 21932 | 1-2 |
| April 3 | Angels | 5 - 4 | Slowey (0-1) | 17084 | 1-3 |
| April 4 | Royals | 4 - 3 | Bale (0-1) | 21847 | 2-3 |
| April 5 | Royals | 6 - 4 | Meche (0-1) | 21262 | 3-3 |
| April 6 | Royals | 3 - 1 | Bonser (0-2) | 21765 | 3-4 |
| April 7 | @ White Sox | 7 - 4 | Guerrier (0-1) | 38082 | 3-5 |
| April 9 | @ White Sox | 12 - 5 | Danks (0-1) | 16499 | 4-5 |