1988 African Cup of Champions Clubs Second round Second round

| Team_1 | Agg_ | Team_2 | _1st_leg | _2nd_leg |
|---|---|---|---|---|
| Iwuanyanwu Nationale | 4-3 | Tonnerre Yaoundé | 2-0 | 2-3 |
| Africa Sports | 4-2 | Petro Atlético | 3-0 | 1-2 |
| FAR Rabat | 6-2 | AS Police | 5-0 | 1-2 |
| Sunrise Flacq United | 3-5 | Matchedje Maputo | 2-0 | 1-5 |
| FC 105 Libreville | 3-2 | FC Inter-Star | 2-1 | 1-1 |
| ES Sahel | 2-3 | ES Sétif | 2-1 | 0-2 |
| Kabwe Warriors | 1-3 | Al-Hilal | 0-0 | 1-3 |
| Nakivubo Villa SC | 3-6 | Al-Ahly | 2-3 | 1-3 |