1965 VFL season Round 1 Round 1

| Home_team | Home_team_score | Away_team | Away_team_score | Venue | Crowd | Date_ |
|---|---|---|---|---|---|---|
| Fitzroy | 8.16 (64) | Essendon | 11.18 (84) | Brunswick Street Oval | 17500 | 17 April 1965 |
| St Kilda | 8.12 (60) | Collingwood | 8.6 (54) | Moorabbin Oval | 51370 | 17 April 1965 |
| Hawthorn | 8.6 (54) | Carlton | 12.19 (91) | Glenferrie Oval | 36000 | 17 April 1965 |
| North Melbourne | 4.12 (36) | South Melbourne | 6.10 (46) | City of Coburg Oval | 13774 | 19 April 1965 |
| Richmond | 6.5 (41) | Melbourne | 7.5 (47) | MCG | 36283 | 19 April 1965 |
| Geelong | 5.5 (35) | Footscray | 5.3 (33) | Kardinia Park | 23233 | 19 April 1965 |