1990–91 Manchester United F.C. season First Division First Division

| Date_ | Opponents | H_A | Result_F_A | Attendance | League_position |
|---|---|---|---|---|---|
| 25 August 1990 | Coventry City | H | 2 – 0 | 46715 | 4th |
| 28 August 1990 | Leeds United | A | 0 – 0 | 29174 | 3rd |
| 1 September 1990 | Sunderland | A | 1 – 2 | 26105 | 6th |
| 4 September 1990 | Luton Town | A | 1 – 0 | 12576 | 4th |
| 8 September 1990 | Queens Park Rangers | H | 3 – 1 | 43427 | 3rd |
| 16 September 1990 | Liverpool | A | 0 – 4 | 35726 | 6th |
| 22 September 1990 | Southampton | H | 3 – 2 | 41288 | 3rd |
| 29 September 1990 | Nottingham Forest | H | 0 – 1 | 46766 | 5th |
| 20 October 1990 | Arsenal | H | 0 – 1 | 47322 | 7th |