2008 New York Yankees season Game log September

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| September 1 | @ Tigers | 13-9 | Verlander (10-15) | 44336 | 73-64 |
| September 2 | @ Rays | 7-2 | Garza (11-8) | 21629 | 74-64 |
| September 3 | @ Rays | 8-4 | Jackson (11-9) | 25215 | 75-64 |
| September 4 | @ Rays | 7-5 | Rasner (5-10) | 26080 | 75-65 |
| September 5 | @ Mariners | 3-1 | Pettitte (13-12) | 39518 | 75-66 |
| September 6 | @ Mariners | 7-4 | Green (4-5) | 44473 | 76-66 |
| September 7 | @ Mariners | 5-2 | Mussina (17-8) | 42677 | 76-67 |
| September 8 | @ Angels | 12-1 | Pavano (2-1) | 41025 | 76-68 |
| September 9 | @ Angels | 7-1 | Santana (15-6) | 43042 | 77-68 |
| September 10 | @ Angels | 4-2 | Pettitte (13-13) | 39783 | 77-69 |