2010 US Open (tennis) Singles seeds Men's singles

| Seed | Rank_ | Player | Points | Points_defending | Points_won | New_points | Status_ |
|---|---|---|---|---|---|---|---|
| 2 | 2 | Roger Federer | 7215 | 1200 | 720 | 6735 | Semifinals lost to Novak Djokovic [3] |
| 4 | 4 | Andy Murray | 5125 | 180 | 90 | 5035 | 3rd round lost to Stanislas Wawrinka [25] |
| 5 | 5 | Robin Söderling | 4910 | 360 | 360 | 4910 | Quarterfinals lost to Roger Federer [2] |
| 6 | 6 | Nikolay Davydenko | 4285 | 180 | 45 | 4150 | 2nd round lost to Richard Gasquet |
| 7 | 7 | Tomáš Berdych | 3860 | 90 | 10 | 3780 | 1st round lost to Michaël Llodra |
| 8 | 8 | Fernando Verdasco | 3330 | 360 | 360 | 3330 | Quarterfinals lost to Rafael Nadal [1] |
| 9 | 9 | Andy Roddick | 3225 | 90 | 45 | 3180 | 2nd round lost to Janko Tipsarević |