1991 San Diego Chargers season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 1 | September 1, 1991 | at Pittsburgh Steelers | L 26–20 | 55848 |
| 2 | September 8, 1991 | at San Francisco 49ers | L 34–14 | 60753 |
| 3 | September 15, 1991 | Atlanta Falcons | L 13–10 | 44804 |
| 4 | September 22, 1991 | at Denver Broncos | L 27–19 | 73258 |
| 5 | September 29, 1991 | Kansas City Chiefs | L 14–13 | 44907 |
| 6 | October 6, 1991 | at Los Angeles Raiders | W 21–13 | 42787 |
| 7 | October 13, 1991 | at Los Angeles Rams | L 30–24 | 47433 |
| 8 | October 20, 1991 | Cleveland Browns | L 30–24 | 48440 |
| 9 | October 27, 1991 | at Seattle Seahawks | L 20–9 | 58025 |
| 10 | Bye | Bye | Bye | Bye |