John Isner Doubles: 6 (3 titles, 3 runners-up) Doubles: 6 (3 titles, 3 runners-up)

| Outcome | Date_ | Surface | Partner | Opponents | Score |
|---|---|---|---|---|---|
| Winner | July 7, 2008 | Grass | Mardy Fish | Rohan Bopanna Aisam-ul-Haq Qureshi | 6–4, 7–6 (7–1) |
| Winner | February 21, 2010 | Hard | Sam Querrey | Ross Hutchins Jordan Kerr | 6–4, 6–4 |
| Runner-up | May 2, 2010 | Clay | Sam Querrey | Bob Bryan Mike Bryan | 2–6, 3–6 |
| Runner-up | April 9, 2011 | Clay | Sam Querrey | Bob Bryan Mike Bryan | 7–6 (7–4) , 2–6, [5–10] |
| Winner | May 15, 2011 | Clay | Sam Querrey | Mardy Fish Andy Roddick | w/o |
| Runner-up | March 18, 2012 | Hard | Sam Querrey | Marc López Rafael Nadal | 2–6, 6–7 (3–7) |