1963 San Francisco 49ers season Regular season Schedule

| Game | Date_ | Opponent | Result_ | _49ers_points | Opponents | Record | Streak | Attendance |
|---|---|---|---|---|---|---|---|---|
| 8 | November 3 | Detroit Lions | L | 7 | 45 | 1-7 | L2 | 33511 |
| 9 | November 10 | Dallas Cowboys | W | 31 | 24 | 2-7 | W1 | 29563 |
| 10 | November 17 | at New York Giants | L | 14 | 48 | 2-8 | L1 | 62982 |
| 11 | November 24 | at Green Bay Packers | L | 10 | 28 | 2-9 | L2 | 45905 |
| 12 | December 1 | Los Angeles Rams | L | 17 | 21 | 2-10 | L3 | 33321 |
| 13 | December 8 | at Chicago Bears | L | 7 | 27 | 2-11 | L4 | 46994 |
| 14 | December 14 | Green Bay Packers | L | 17 | 21 | 2-12 | L5 | 31031 |