1978 Kansas City Chiefs season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 1 | September 3, 1978 | at Cincinnati Bengals | W 24–23 | 41810 |
| 2 | September 10, 1978 | Houston Oilers | L 20–17 | 40213 |
| 3 | September 17, 1978 | at New York Giants | L 26–10 | 70546 |
| 4 | September 24, 1978 | Denver Broncos | L 23–17 | 60593 |
| 5 | October 1, 1978 | at Buffalo Bills | L 28–13 | 47310 |
| 6 | October 8, 1978 | Tampa Bay Buccaneers | L 30–13 | 38201 |
| 7 | October 15, 1978 | at Oakland Raiders | L 28–6 | 50759 |
| 8 | October 22, 1978 | Cleveland Browns | W 17–3 | 41157 |
| 9 | October 29, 1978 | at Pittsburgh Steelers | L 27–24 | 48185 |
| 10 | November 5, 1978 | Oakland Raiders | L 20–10 | 75418 |