2010 Southeastern Conference football season Week Three Week Three

| Date_ | Time_ | Visiting_team | Home_team | Site | Broadcast | Result_ | Attendance |
|---|---|---|---|---|---|---|---|
| September 18 | 12:00pm | #12 Arkansas | Georgia | Sanford Stadium • Athens, GA | ESPN | ARK 31–24 | 92746 |
| September 18 | 12:21pm | Vanderbilt | Ole Miss | Vaught-Hemingway Stadium • Oxford, MS | SEC Network | VAN 28–14 | 51667 |
| September 18 | 3:30pm | #10 Florida | Tennessee | Neyland Stadium • Knoxville, TN | CBS | FLA 31–17 | 102455 |
| September 18 | 3:30pm | #1 Alabama | Duke | Wallace Wade Stadium • Durham, NC | ABC | W 62–13 | 39042 |
| September 18 | 7:00pm | Mississippi State | #15 LSU | Tiger Stadium • Baton Rouge, LA | ESPNU | LSU 29–7 | 92538 |
| September 18 | 7:00pm | Clemson | #16 Auburn | Jordan-Hare Stadium • Auburn, AL | ESPN | W 27–24 OT | 87451 |
| September 18 | 7:00pm | Akron | Kentucky | Commonwealth Stadium • Lexington, KY | FSN | W 47–10 | 64014 |