2000 Toronto Blue Jays season Game log May

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| May 21 | White Sox | 2 - 1 | Castillo (1-4) | 18264 | 22-23 |
| May 22 | White Sox | 4 - 3 | Howry (0-1) | 19167 | 23-23 |
| May 23 | @ Red Sox | 3 - 2 | Martínez (7-2) | 33402 | 24-23 |
| May 24 | @ Red Sox | 6 - 3 (11) | Frascatore (0-1) | 31250 | 24-24 |
| May 25 | @ Red Sox | 11 - 6 | Schourek (2-4) | 32716 | 25-24 |
| May 26 | @ Tigers | 8 - 2 | Brocail (1-3) | 33068 | 26-24 |
| May 27 | @ Tigers | 4 - 3 | Quantrill (0-2) | 29584 | 26-25 |
| May 28 | @ Tigers | 12 - 7 | Blair (2-1) | 29105 | 27-25 |
| May 30 | Twins | 4 - 1 | Escobar (4-6) | 16371 | 27-26 |
| May 31 | Twins | 4 - 2 | Radke (3-6) | 17305 | 28-26 |