2010 French Open Singles seeds Women's singles

| Seed | Rank_ | Player | Points | Points_defending | Points_won | New_points | Status_ |
|---|---|---|---|---|---|---|---|
| 16 | 17 | Yanina Wickmayer | 3050 | 100 | 160 | 3110 | 3rd round lost to Daniela Hantuchová [22] |
| 18 | 19 | Shahar Pe`er | 2895 | 0 | 280 | 3175 | 4th round lost to Serena Williams [1] |
| 19 | 20 | Nadia Petrova | 2795 | 100 | 500 | 3195 | Quarterfinals lost to Elena Dementieva [5] |
| 20 | 21 | María José Martínez Sánchez | 2635 | 160 | 5 | 2480 | 1st round lost to Akgul Amanmuradova |
| 21 | 22 | Vera Zvonareva | 2625 | 0 | 100 | 2725 | 2nd round lost to Anastasia Rodionova |
| 22 | 23 | Justine Henin | 2575 | 0 | 280 | 2855 | 4th round lost to Samantha Stosur [7] |
| 23 | 24 | Daniela Hantuchová | 2010 | 5 | 280 | 2285 | 4th round lost Jelena Janković [4] |