1999 Buffalo Bills season NFL Draft NFL Draft

| Round | Pick | Player | Position_ | School_Club_Team |
|---|---|---|---|---|
| 1 | 23 | Antoine Winfield | Defensive back | Ohio State |
| 2 | 53 | Peerless Price | Wide receiver | Tennessee |
| 3 | 86 | Shawn Bryson | Fullback | Tennessee |
| 4 | 119 | Keith Newman | Outside linebacker | North Carolina |
| 4 | 122 | Bobby Collins | Tight end | North Alabama |
| 5 | 156 | Jay Foreman | Inside linebacker | Nebraska |
| 6 | 194 | Armon Hatcher | Safety | Oregon State |
| 7 | 230 | Sheldon Jackson | Tight End | Nebraska |
| 7 | 248 | Bryce Fisher | Defensive end | Air Force |