2008 Chicago White Sox season Game log September

| Date_ | Opponent | Score | Loss | Time_ | Att_ | Record |
|---|---|---|---|---|---|---|
| September 24 | @ Twins | 2–3 | Buehrle (14–12) | 2:42 | 42126 | 86–71 |
| September 25 | @ Twins | 6 – 7 (10) | Jenks (3–1) | 3:27 | 43601 | 86–72 |
| September 26 | Indians | 8–11 | Danks (11–9) | 3:36 | 36494 | 86–73 |
| September 27 | Indians | 6–12 | Vázquez (12–16) | 3:05 | 36031 | 86–74 |
| September 28 | Indians | 5–1 | Bullington (0–2) | 2:29 | 33396 | 87–74 |
| September 29 | Tigers | 8–2 | Galarraga (13–7) | 3:14 | 35923 | 88–74 |
| September 30 | Twins | 1–0 | Blackburn (11–11) | 2:20 | 40354 | 89–74 |