1980 Toronto Blue Jays season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 21 | @ Royals | 7–1 | Gale (0–2) | 21117 | 5–4 |
| April 22 | @ Royals | 7–2 | Mirabella (1–1) | 16993 | 5–5 |
| April 23 | @ Royals | 7–4 | McLaughlin (0–1) | 18855 | 5–6 |
| April 25 | @ Brewers | 5–3 | Sorensen (1–2) | 9902 | 6–6 |
| April 26 | @ Brewers | 4–0 | Caldwell (2–1) | 11038 | 7–6 |
| April 27 | @ Brewers | 8–2 | Haas (1–3) | 11099 | 8–6 |
| April 28 | Royals | Postponed (rain) Rescheduled for August 8 | Postponed (rain) Rescheduled for August 8 | Postponed (rain) Rescheduled for August 8 | Postponed (rain) Rescheduled for August 8 |
| April 29 | Royals | 3–1 | Leonard (0–3) | 11553 | 9–6 |
| April 30 | Royals | 3–0 | Jefferson (0–1) | 14029 | 9–7 |