1980 Cleveland Browns season NFL Draft NFL Draft

| Round | Overall | Player | Position_ | School_Club_Team |
|---|---|---|---|---|
| 1 | 27 | Charles White | Running Back | USC |
| 2 | 54 | Cleveland Crosby | Defensive End | Wisconsin |
| 3 | 72 | Cliff Odom | Linebacker | University of Texas at Arlington |
| 4 | 99 | Ron Crews | Nose Tackle | UNLV |
| 4 | 109 | Paul McDonald | Quarterback | USC |
| 5 | 116 | Elvis Franks | Defensive End | Morgan State |
| 8 | 209 | Jeff Copeland | Linebacker | Texas Tech |
| 9 | 236 | Roy De Walt | Running Back | University of Texas at Arlington |
| 10 | 263 | Kevin Fidel | Center | San Diego State |
| 11 | 294 | Roland Sales | Running Back | Arkansas |
| 12 | 321 | Marcus Jackson | Defensive End | Purdue |