2007–08 Eccellenza season Second round Second round

| Team_1 | Agg_ | Team_2 | _1st_leg | _2nd_leg |
|---|---|---|---|---|
| 1 | Manzanese (Friuli V.G.) | 0–3 | Suzzara (Lombardy B) | 0–2 |
| 2 | Edo Mestre (Veneto B) | 4–5 | Albignasego (Veneto A) | 3–2 |
| 3 | Cantù San Paolo (Lombardy A) | 1–2 | Casoli (Abruzzo) | 1–1 |
| 4 | Sangimignano (Tuscany A) | 5–2 | Copparese (Emilia-Romagna B) | 3–1 |
| 5 | Aprilia (Lazio A) | 0–2 | Boville Ernica (Lazio B) | 0–0 |
| 6 | Battipagliese (Campania B) | 2–4 | Palazzolo (Sicily B) | 1–0 |
| 7 | Ricigliano (Basilicata) | 3–9 | Trapani (Sicily A) | 2–5 |