2000 Cleveland Browns season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Attendance |
|---|---|---|---|---|
| 1 | September 3, 2000 | Jacksonville Jaguars | L 27–7 | 72418 |
| 2 | September 10, 2000 | at Cincinnati Bengals | W 24–7 | 64006 |
| 3 | September 17, 2000 | Pittsburgh Steelers | W 23–20 | 73018 |
| 4 | September 24, 2000 | at Oakland Raiders | L 36–10 | 45702 |
| 5 | October 1, 2000 | Baltimore Ravens | L 12–0 | 73018 |
| 6 | October 8, 2000 | at Arizona Cardinals | L 29–21 | 39148 |
| 7 | October 15, 2000 | at Denver Broncos | L 44–10 | 75811 |
| 8 | October 22, 2000 | at Pittsburgh Steelers | L 22–0 | 57659 |
| 9 | October 29, 2000 | Cincinnati Bengals | L 12–3 | 73118 |
| 10 | November 5, 2000 | New York Giants | L 24–3 | 72718 |