2010 NHL Entry Draft Round one Round one

| Pick_ | Player | Nationality | Position_ | NHL_team | Team_from | League_from |
|---|---|---|---|---|---|---|
| 22 | Jarred Tinordi | United States | D | Montreal Canadiens (from Phoenix) 6 | U.S. National U-18 Team | United States Hockey League |
| 23 | Mark Pysyk | Canada | D | Buffalo Sabres | Edmonton Oil Kings | Western Hockey League |
| 24 | Kevin Hayes | United States | RW | Chicago Blackhawks (from New Jersey via Atlanta) 7 | Noble and Greenough School | United States High School-MA |
| 25 | Quinton Howden | Canada | LW | Florida Panthers (from Vancouver) 8 | Moose Jaw Warriors | Western Hockey League |
| 26 | Evgeny Kuznetsov | Russia | C | Washington Capitals | Traktor Chelyabinsk | Kontinental Hockey League (Russia) |
| 27 | Mark Visentin | Canada | G | Phoenix Coyotes (from Montreal) 9 | Niagara IceDogs | Ontario Hockey League |
| 28 | Charlie Coyle | United States | C/RW | San Jose Sharks | South Shore Kings | Eastern Junior Hockey League |