2010 US Open (tennis) Singles seeds Men's singles

| Seed | Rank_ | Player | Points | Points_defending | Points_won | New_points | Status_ |
|---|---|---|---|---|---|---|---|
| 24 | 26 | Ernests Gulbis | 1515 | 10 | 10 | 1515 | 1st round lost to Jérémy Chardy |
| 25 | 27 | Stanislas Wawrinka | 1510 | 10 | 360 | 1860 | Quarterfinals lost to Mikhail Youzhny [12] |
| 26 | 28 | Thomaz Bellucci | 1480 | 70 | 45 | 1455 | 2nd round lost to Kevin Anderson |
| 27 | 29 | Fernando González | 1340 | 360 | 10 | 990 | 1st round lost to Ivan Dodig [Q] |
| 28 | 30 | Radek Štěpánek | 1320 | 180 | 10 | 1150 | 1st round lost to Julien Benneteau |
| 29 | 31 | Philipp Kohlschreiber | 1315 | 90 | 45 | 1270 | 2nd round lost to Gilles Simon |
| 30 | 32 | Juan Mónaco | 1235 | 10 | 10 | 1235 | 1st round lost to Peter Polansky [Q] |
| 31 | 33 | David Nalbandian | 1235 | 0 | 90 | 1325 | 3rd round lost to Fernando Verdasco [8] |