2001 Major League Baseball Draft First Round Selections First Round Selections

| Pick | Player | Team | Position_ | School |
|---|---|---|---|---|
| 1 | Joe Mauer | Minnesota Twins | C | St. Paul, MN ( Cretin-Derham Hall HS ) |
| 2 | Mark Prior | Chicago Cubs | RHP | University of Southern California |
| 3 | Dewon Brazelton | Tampa Bay Devil Rays | RHP | Middle Tennessee State University |
| 4 | Gavin Floyd | Philadelphia Phillies | RHP | Baltimore, MD ( Mount Saint Joseph College ) |
| 5 | Mark Teixeira | Texas Rangers | 3B | Georgia Tech |
| 6 | Josh Karp | Montreal Expos | RHP | University of California |
| 7 | Chris Smith | Baltimore Orioles | LHP | Cumberland University |
| 8 | John Van Benschoten | Pittsburgh Pirates | RHP | Kent State University |
| 9 | Colt Griffin | Kansas City Royals | RHP | Marshall, TX |