2008 New England Patriots season Regular season Regular season

| Week | Kickoff | Date_ | Opponent | Result_ | Record | Game_Site | NFL_com_Recap |
|---|---|---|---|---|---|---|---|
| 14 | 4:05 PM EST | December 7, 2008 | Seattle Seahawks | W 24–21 | 8–5 | Qwest Field | Recap |
| 15 | 4:15 PM EST | December 14, 2008 | Oakland Raiders | W 49–26 | 9–5 | Oakland-Alameda County Coliseum | Recap |
| 16 | 1:00 PM EST | December 21, 2008 | Arizona Cardinals | W 47–7 | 10–5 | Gillette Stadium | Recap |
| 17 | 1:00 PM EST | December 28, 2008 | Buffalo Bills | W 13–0 | 11–5 | Ralph Wilson Stadium | Recap |