1980 Baltimore Colts season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Record | Game_Site | Attendance |
|---|---|---|---|---|---|---|
| 1 | September 7, 1980 | at New York Jets | W 17–14 | 1–0 | Shea Stadium | 50777 |
| 2 | September 14, 1980 | Pittsburgh Steelers | L 17–20 | 1–1 | Memorial Stadium | 54914 |
| 3 | September 21, 1980 | at Houston Oilers | L 16–21 | 1–2 | Astrodome | 47878 |
| 4 | September 28, 1980 | New York Jets | W 35–21 | 2–2 | Memorial Stadium | 33373 |
| 5 | October 5, 1980 | at Miami Dolphins | W 30–17 | 3–2 | Miami Orange Bowl | 50631 |
| 6 | October 12, 1980 | at Buffalo Bills | W 17–12 | 4–2 | Rich Stadium | 73634 |
| 7 | October 19, 1980 | New England Patriots | L 21–37 | 4–3 | Memorial Stadium | 53924 |