2005 Cleveland Indians season Game log May

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| May 11 | @ Angels | 9 - 3 | Escobar (1-2) | 35508 | 14-19 |
| May 13 | Blue Jays | 6 - 4 | Lilly (1-4) | 19637 | 15-19 |
| May 14 | Blue Jays | 3 - 2 | Frasor (1-3) | 22525 | 16-19 |
| May 15 | Blue Jays | 5 - 2 | Sabathia (2-3) | 23446 | 16-20 |
| May 16 | Angels | 3 - 1 | Lee (4-2) | 13729 | 16-21 |
| May 17 | Angels | 13 - 5 | Santana (0-1) | 15033 | 17-21 |
| May 18 | Angels | 2 - 1 | Westbrook (1-7) | 19030 | 17-22 |
| May 20 | @ Reds | 2 - 1 | Millwood (1-4) | 25412 | 17-23 |
| May 21 | @ Reds | 5 -3 | Ramírez (0-2) | 31083 | 18-23 |
| May 22 | @ Reds | 9 - 2 | Ortiz (1-3) | 21862 | 19-23 |