1989 Copa Libertadores Round of 16 Round of 16

| Team_1 | Agg_ | Team_2 | _1st_leg | _2nd_leg |
|---|---|---|---|---|
| Atlético Nacional | 3-2 | Racing | 2-0 | 1-2 |
| Millonarios | 3-3 (4-3 pk ) | Bolivar | 0-1 | 3-2 |
| Cobreloa | 1-0 | Deportivo Quito | 0-0 | 1-0 |
| Danubio | 3-1 | Nacional | 3-1 | 0-0 |
| Peñarol | 3-8 | Internacional | 2-6 | 1-2 |
| Bahia | 3-2 | Universitario | 1-1 | 2-1 |
| Deportivo Táchira | 3-3 (2-3 pk ) | Sol de América | 0-3 | 3-0 |
| Boca Juniors | 5-5 (6-7 pk ) | Olimpia | 0-2 | 5-3 |