1988 Cleveland Browns season NFL Draft NFL Draft

| Pick_ | NFL_Team | Player | Position_ | College |
|---|---|---|---|---|
| 21 | Cleveland Browns | Clifford Charlton | Outside Linebacker | Florida |
| 50 | Cleveland Browns | Michael Dean Perry | Defensive Tackle | Clemson |
| 77 | Cleveland Browns | Van Waiters | Outside Linebacker | Indiana |
| 103 | Cleveland Browns | Anthony Blaylock | Corner Back | Winston-Salem |
| 188 | Cleveland Browns | Thane Gash | Defensive Back | East Tennessee State |