1980 Baltimore Colts season Schedule Schedule

| Week | Date_ | Opponent | Result_ | Record | Game_Site | Attendance |
|---|---|---|---|---|---|---|
| 8 | October 26, 1980 | St. Louis Cardinals | L 10–17 | 4–4 | Memorial Stadium | 33506 |
| 9 | November 2, 1980 | at Kansas City Chiefs | W 31–24 | 5–4 | Arrowhead Stadium | 52383 |
| 10 | November 9, 1980 | Cleveland Browns | L 27–28 | 5–5 | Memorial Stadium | 45369 |
| 11 | November 16, 1980 | at Detroit Lions | W 10–9 | 6–5 | Pontiac Silverdome | 77677 |
| 12 | November 23, 1980 | at New England Patriots | L 21–47 | 6–6 | Schaeffer Stadium | 60994 |
| 13 | November 30, 1980 | Buffalo Bills | W 28–24 | 7–6 | Memorial Stadium | 36184 |
| 14 | December 7, 1980 | at Cincinnati Bengals | L 33–34 | 7–7 | Riverfront Stadium | 35651 |
| 15 | December 14, 1980 | Miami Dolphins | L 14–24 | 7–8 | Memorial Stadium | 30564 |