2006 CFL Draft Round six Round six

| Pick_ | CFL_Team | Player | Position_ | College |
|---|---|---|---|---|
| 43 | Montreal Alouettes (via Winnipeg via Hamilton) | Danny Desriveaux | WR | Richmond |
| 44 | Calgary Stampeders (via Winnipeg) | Andre Knights | DB | St. Mary`s |
| 45 | Saskatchewan Roughriders | Stephen Hughes | RB | Calgary |
| 46 | Calgary Stampeders | Marc Trepanier | LB | Montreal |
| 47 | Toronto Argonauts | Clifton Dawson | RB | Harvard |
| 48 | BC Lions | Jason Ward | DL | Connecticut |
| 49 | Winnipeg Blue Bombers (via Montreal) | Dexter Ross | DE | Minot State |
| 50 | Edmonton Eskimos | Greig Longchamps | OL | Montreal |