Most wins by a starting quarterback (NFL) Top 50 quarterbacks in NFL history Quarterbacks Ranked by Regular Season Wins, then Winning Percentage

| Rank_ | Quarterback | Seasons | Teams | Team_Wins | Team_Losses | Career_Wins | Career_Losses | Ties_ |
|---|---|---|---|---|---|---|---|---|
| 1 | Brett Favre Category:Articles with hCards | 1991 | Atlanta | 0 | 0 | 186 | 112 | 0 |
| 1 | Brett Favre Category:Articles with hCards | 1992-2007 | Green Bay | 160 | 93 | 186 | 112 | 0 |
| 1 | Brett Favre Category:Articles with hCards | 2008 | NY Jets | 9 | 7 | 186 | 112 | 0 |
| 1 | Brett Favre Category:Articles with hCards | 2009-2010 | Minnesota | 17 | 12 | 186 | 112 | 0 |
| 2 | Peyton Manning Category:Articles with hCards * | 1998-2011 | Indianapolis | 141 | 67 | 161 | 71 | 0 |
| 2 | Peyton Manning Category:Articles with hCards * | 2012–present | Denver | 20 | 4 | 161 | 71 | 0 |
| 3 | Elway, John John Elway ** | 1983-1998 | Denver | 148 | 82 | 148 | 82 | 1 |