1950–51 FA Cup Second Round Proper Second Round Proper

| Tie_no | Home_team | Score | Away_team | Date_ |
|---|---|---|---|---|
| 1 | Ashington | 1–2 | Rochdale | 9 December 1950 |
| 2 | Bristol City | 2–1 | Wrexham | 9 December 1950 |
| 3 | Reading | 4–0 | Dartford | 9 December 1950 |
| 4 | Crewe Alexandra | 2–2 | Plymouth Argyle | 9 December 1950 |
| Replay | Plymouth Argyle | 3–0 | Crewe Alexandra | 13 December 1950 |
| 5 | Bristol Rovers | 2–2 | Gillingham | 9 December 1950 |
| Replay | Gillingham | 1–1 | Bristol Rovers | 13 December 1950 |
| 2nd replay | Bristol Rovers | 2–1 | Gillingham | 18 December 1950 |
| 6 | Brighton & Hove Albion | 2–0 | Ipswich Town | 9 December 1950 |
| 7 | Rhyl | 0–1 | Norwich City | 9 December 1950 |
| 8 | Millwall | 1–1 | Bradford Park Avenue | 9 December 1950 |