2006 Oakland Athletics season Game log April

| Date_ | Opponent | Score | Loss | Attendance | Record |
|---|---|---|---|---|---|
| April 3 | Yankees | 2-15 | Zito (0-1) | 35077 | 0-1 |
| April 4 | Yankees | 4-3 | Proctor (0-1) | 31284 | 1-1 |
| April 5 | Yankees | 9-4 | Wright (0-1) | 30165 | 2-1 |
| April 6 | @ Mariners | 2-6 | Loaiza (0-1) | 22701 | 2-2 |
| April 7 | @ Mariners | 5-0 | Hernández (0-1) | 30612 | 3-2 |
| April 8 | @ Mariners | 3-0 | Moyer (0-1) | 37904 | 4-2 |
| April 9 | @ Mariners | 6-4 | Piñeiro (1-1) | 27139 | 5-2 |
| April 11 | @ Twins | 6-7 | Haren (0-1) | 48911 | 5-3 |
| April 12 | @ Twins | 5-6 | Loaiza (0-2) | 22603 | 5-4 |
| April 13 | @ Twins | 2-8 | Blanton (1-1) | 13520 | 5-5 |
| April 14 | Rangers | 3-6 | Zito (1-2) | 14049 | 5-6 |