1988 NCAA Women's Division I Basketball Tournament First and second rounds First and second rounds

| Region | Host_ | Venue | City | State_ |
|---|---|---|---|---|
| East | Villanova University | The Pavilion | Villanova | Pennsylvania |
| East | Saint John`s University | Alumni Hall (Carnesecca) | Queens | New York |
| East | Rutgers University | Louis Brown Athletic Center | Piscataway | New Jersey |
| East | University of Virginia | University Hall (University of Virginia) | Charlottesville | Virginia |
| East | University of Tennessee | Stokely Athletic Center | Knoxville | Tennessee |
| East | James Madison University | James Madison University Convocation Center | Harrisonburg | Virginia |
| Mideast | Saint Joseph`s University | Alumni Memorial Fieldhouse | Philadelphia | Pennsylvania |
| Mideast | La Salle University | Hayman Hall (Tom Gola Arena) | Philadelphia | Pennsylvania |
| Mideast | University of Maryland | Cole Field House | College Park | Maryland |
| Mideast | Ohio State University | St. John Arena | Columbus | Ohio |