DNA sequencer Comparison Comparison

| Sequencer | Ion_Torrent_PGM | _454_GS_FLX | HiSeq_2000 | SOLiDv4 | PacBio | Sanger_3730xl |
|---|---|---|---|---|---|---|
| Read length | 200-400 bp | 700 bp | 100x100 bp paired end | 50x50 bp paired end | 1,500-5,000 bp (avg) | 400-900 bp |
| Cost per run | $350 USD | $7,000 USD | $6,000 USD (30x human genome) | $4,000 USD | $300 USD | $4 USD (single read/reaction) |
| Cost per Mb | $1.00 USD | $10 USD | $0.07 USD | $0.13 USD | $2.00 USD | $2400 USD |