Iowa State Cyclones men's basketball Record vs. Big 12 opponents Record vs. Big 12 opponents

| Iowa_State_vs_ | Overall_Record | in_Ames | at_Opponents_Venue | at_Neutral_Site | Last_5_Meetings | Last_10_Meetings | Current_Streak | Since_Beginning_of_Big_12 |
|---|---|---|---|---|---|---|---|---|
| Baylor | ISU, 14–8 | ISU, 10–0 | BU, 2–7 | ISU, 2–1 | ISU, 4–1 | ISU, 6–4 | W 3 | ISU, 13–7 |
| Kansas | KU, 174–59 | KU, 67–37 | KU, 89–15 | KU, 18–7 | KU, 4–1 | KU, 9–1 | L 3 | KU, 28–7 |
| Kansas State | KSU, 134–77 | KSU, 50–48 | KSU, 78–21 | ISU, 9–7 | ISU, 3–2 | KSU, 6–4 | L 1 | KSU, 18–15 |
| Oklahoma | OU, 111–79 | ISU, 46–37 | OU, 61–22 | OU, 13–11 | ISU, 4–1 | Tied, 5–5 | W 1 | OU, 13–7 |
| Oklahoma State | OSU, 62–53 | ISU, 34–14 | OSU, 36–13 | OSU, 12–6 | OSU, 3–2 | OSU, 7–3 | W 1 | OSU, 16–5 |