2010 Campeonato Brasileiro Série A Managerial changes Managerial changes

| Team | Outgoing_manager | Manner_of_departure | Date_of_vacancy | Position_in_table | Replaced_by | Date_of_appointment |
|---|---|---|---|---|---|---|
| Cruzeiro | Adílson Batista | Resigned | June 2 | 6th | Cuca | June 8 |
| Atlético Goianiense | Geninho | Resigned | June 7 | 20th | Roberto Fernandes | June 14 |
| Vasco da Gama | Celso Roth | Left to sign with Internacional | June 12 | 19th | PC Gusmão | June 13 |
| Internacional | Enderson Moreira (caretaker) | Replaced | June 12 | 16th | Celso Roth | June 12 |
| Ceará | PC Gusmão | Left to sign with Vasco da Gama | June 13 | 2nd | Estevam Soares | June 13 |
| Palmeiras | Jorge Parraga (caretaker) | Replaced | June 13 | 10th | Luis Felipe Scolari | June 13 |
| Avaí | Péricles Chamusca | Left to sign with Al-Arabi | July 1 | 12th | Antônio Lopes | July 5 |
| Corinthians | Mano Menezes | Left to sign with Brazil | July 24 | 2nd | Adílson Batista | July 24 |