Question: What is the patent year of the Benzodiazepine medicine that has a 5–200 half life

text: List of benzodiazepines
Pharmacokinetic properties of various benzodiazepines
Data in the table below is taken from the Ashton `` Benzodiazepine Equivalency Table '' . [ 4 ] [ 11 ] [ 12 ] [ 13 ]
The below tables contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses. The elimination half-life is how long it takes for half of the drug to be eliminated by the body. Time to peak refers to when maximum levels of the drug in the blood occur after a given dose. Benzodiazepines generally share the same pharmacological properties, such as anxiolytic, sedative, hypnotic, skeletal muscle relaxant, amnesic, and anticonvulsant effects. Variation in potency of certain effects may exist amongst individual benzodiazepines. Some benzodiazepines produce active metabolites. Active metabolites are produced when a person's body metabolizes the drug into compounds that share a similar pharmacological profile to the parent compound and thus are relevant when calculating how long the pharmacological effects of a drug will last. Long-acting benzodiazepines with long-acting active metabolites, such as diazepam and chlordiazepoxide, are often prescribed for benzodiazepine or alcohol withdrawal as well as for anxiety if constant dose levels are required throughout the day. Shorter-acting benzodiazepines are often preferred for insomnia due to their lesser hangover effect. It is fairly important to note that elimination half-life of diazepam and chlordiazepoxide, as well as other long half-life benzodiazepines, is twice as long in the elderly compared to younger individuals. Individuals with an impaired liver also metabolize benzodiazepines more slowly. Many doctors[who?]
Drug name Common trade names Year approved .mw-parser-output .nobold { font-weight : normal } ( US FDA ) Time to peak onset of action ( hours ) Elimination half-life of active metabolite ( hours ) Therapeutic use
Adinazolam Deracyn Research chemical 1-2 3 anxiolytic , antidepressant
Alprazolam Xanax , Helex , Xanor , Trankimazin , Onax , Alprox , Misar , Restyl , Solanax , Tafil , Neurol , Frontin , Kalma , Ksalol 1981 1-2 10-20 anxiolytic , antidepressant
Bentazepam Thiadipona  1-3 2-4 anxiolytic
Bretazenil    2.5 anxiolytic , anticonvulsant
Bromazepam Lectopam , Lexaurin , Lexatin , Lexotanil , Lexotan , Bromam 1981 1-3 20-40 anxiolytic , hypnotic
Bromazolam  Research chemical   anxiolytic
Brotizolam Lendormin , Dormex , Sintonal , Noctilan  0.5-2 4-5 hypnotic
Camazepam Albego , Limpidon , Paxor  0.5-2 6-29 anxiolytic
Chlordiazepoxide Librium , Risolid , Elenium 1960 1.5-4 5-200 anxiolytic
Cinazepam Levana  2-4 60 hypnotic , anxiolytic
Cinolazepam Gerodorm  0.5-2 9 hypnotic
Clobazam Onfi , Frisium , Urbanol 2011 1-3 8-60 anxiolytic , anticonvulsant
Clonazepam Rivatril , Rivotril , Klonopin , Iktorivil , Paxam 1975 1-4 19.5-50 anticonvulsant , anxiolytic , muscle relaxant
Clonazolam  Research chemical 0.5-1.5 10-18 anxiolytic , anticonvulsant , hypnotic , muscle relaxant
Clorazepate Tranxene , Tranxilium 1972 Variable 32-152 anxiolytic , anticonvulsant
Clotiazepam Veratran , Clozan , Rize  1-3 4 anxiolytic
Cloxazolam Sepazon , Olcadil  2-5 80-105 anxiolytic , anticonvulsant
Delorazepam Dadumir  1-2 80-105 anxiolytic , amnesic
Deschloroetizolam [ d ] [ lower-alpha 4 ]  Research chemical   anxiolytic
Diazepam Antenex , Apaurin , Apzepam , Apozepam , Diazepan , Hexalid , Normabel , Pax , Stesolid , Stedon , Tranquirit , Valium , Vival , Valaxona 1963 1-1.5 32-205 anxiolytic , anticonvulsant , muscle relaxant , amnesic