Question: In what year did Spanish conquistadors first arrive in the South American country that has an area of 406,752 square km ?

text: List of sovereign states and dependent territories in South America
Sovereign states -- Sovereign states having the largest part of their territories in South America
Further information : Sovereign state A sovereign state is a political association with effective sovereignty over a population for whom it makes decisions in the national interest . [ 2 ] According to the Montevideo convention , a state must have a permanent population , a defined territory , a government , and the capacity to enter into relations with other states . [ 3 ] The following states are all members of the United Nations [ 4 ] and members of the Union of South American Nations . [ 5 ]
This is a list of sovereign states and dependent territories in South America. It includes both fully recognized states and dependent territories of both South American and non-South American states. It lists 12 sovereign states and 3 non-sovereign territories. South America is bordered on the west by the Pacific Ocean and on the north and east by the Atlantic Ocean. North America and the Caribbean Sea lie to the northwest. South America has an area of approximately 17,840,000 square kilometres (6,890,000 sq mi), or almost 3.5% of the Earth's surface. As of 2008, its population is more than 380 million, according to estimates of population in The World Factbook. South America ranks fourth among all continents in area (after Asia, Africa, and North America) and fifth in population (after Asia, Africa, Europe, and North America). The division between North and South America is unclear, lying somewhere in the Isthmus of Panama. However, Panama is not considered transcontinental, and is generally considered to be wholly a part of North America.
English short and formal names , and ISO code Domestic short and formal names Capital Population Area
Argentina Argentine Republic ARG Spanish : Argentina - República Argentina Buenos Aires Spanish : Ciudad de Buenos Aires 45,034,295 2,780,400 km ( 1,073,518 sq mi )
Bolivia Plurinational State of Bolivia BOL Spanish : Bolivia - Estado Plurinacional de Bolivia Sucre ( official ) and La Paz ( seat of government ) Spanish : Sucre 11,610,155 1,098,581 km ( 424,164 sq mi )
Brazil Federative Republic of Brazil BRA Portuguese : Brasil - República Federativa do Brasil Brasília Portuguese : Brasília 212,003,366 8,514,877 km ( 3,287,612 sq mi )
Chile Republic of Chile Spanish : Chile - República de Chile Santiago Spanish : Santiago 19,087,036 756,102 km ( 291,933 sq mi )
Colombia Republic of Colombia COL Spanish : Colombia - República de Colombia Bogotá / Santa Fe de Bogotá Spanish : Bogotá 50,750,920 1,138,910 km ( 439,736 sq mi )
Ecuador Republic of Ecuador ECU Spanish : Ecuador - República del Ecuador Quito Spanish : Quito 17,549,591 283,561 km ( 109,484 sq mi )
Guyana Co-operative Republic of Guyana GUY English : Guyana - Co-operative Republic of Guyana Georgetown English : Georgetown 785,031 214,969 km ( 83,000 sq mi )
Paraguay Republic of Paraguay PRY Spanish : Paraguay - República del Paraguay Guarani : Paraguai - Tetã Paraguai Asunción Spanish : Asunción 7,098,318 406,752 km ( 157,048 sq mi )
Peru Republic of Peru PER Aymara : Perú Quechua : Perú Spanish : Perú - República del Perú Lima Spanish : Lima 32,827,236 1,285,216 km ( 496,225 sq mi )
Suriname Republic of Suriname SUR Dutch : Suriname - Republiek Suriname Paramaribo Dutch : Paramaribo 584,625 163,820 km ( 63,251 sq mi )
Uruguay Eastern Republic of Uruguay URY Spanish : Uruguay - República Oriental del Uruguay Portuguese : Uruguai - República Oriental do Uruguai Montevideo Spanish : Montevideo 3,469,225 176,215 km ( 68,037 sq mi )
Venezuela Bolivarian Republic of Venezuela VEN Spanish : Venezuela - República Bolivariana de Venezuela Caracas Spanish : Caracas 28,295,350 912,050 km ( 352,144 sq mi )