Question: What is the Epitope of the Human Blood group system that is a red blood cell surface antigen discovered in 1962 ?

text: Human blood group systems
Blood group systems

The term human blood group systems is defined by International Society of Blood Transfusion as systems in the human species where cell-surface antigens - in particular, those on blood cells - are controlled at a single gene locus or by two or more very closely linked homologous genes with little or no observable recombination between them, and include the common ABO and Rh (Rhesus) antigen systems, as well as many others; thirty-five major human systems are identified as of November 2014. In addition to the ABO and Rh systems, the antigens expressed on blood cell membrane surfaces include 346 red blood cell antigens and 33 platelet antigens, as defined serologically. [better source needed] The genetic basis for most of these antigens lie in 46 red blood cell and 6 platelet genes. [citation needed] An individual, for example, can be AB RhD positive, and at the same time M and N positive in the MNS system, K positive in the Kell system, and Lea or Leb positive in the Lewis system,[citation needed] where these and many of the systems are named for patients in whom the corresponding antibodies were first detected. [citation needed]
ISBT No System name System symbol Epitope or carrier , notes Chromosome
001 ABO ABO Carbohydrate ( N-Acetylgalactosamine , galactose ) . A , B and H antigens mainly elicit IgM antibody reactions , although anti-H is very rare , see the Hh antigen system ( Bombay phenotype , ISBT # 18 ) 9q34.2
002 MNS MNS GPA / GPB ( glycophorins A and B ) . Main antigens M , N , S , s 4q31.21
003 P P Glycolipid . Three antigens : P 1 , P , and P 22q13.2
004 Rh RH Protein . C , c , D , E , e antigens ( there is no d antigen ; lowercase d indicates the absence of D ) 1p36.11
005 Lutheran LU Protein ( member of the immunoglobulin superfamily ) . Set of 21 antigens 19q13.32
006 Kell KEL Glycoprotein . K 1 can cause hemolytic disease of the newborn ( anti-Kell ) , which can be severe 7q34
007 Lewis LE Carbohydrate ( fucose residue ) . Main antigens Le and Le - associated with tissue ABH antigen secretion 19p13.3
008 Duffy FY Protein ( chemokine receptor ) . Main antigens Fy and Fy . Individuals lacking Duffy antigens altogether are immune to malaria caused by Plasmodium vivax and Plasmodium knowlesi 1q23.2
009 Kidd JK Protein ( urea transporter ) . Main antigens Jk and Jk 18q12.3
010 Diego DI Glycoprotein ( band 3 , AE 1 , or anion exchange ) . Positive blood is found only among East Asians and Native Americans 17q21.31
011 Yt YT Protein ( AChE , acetylcholinesterase ) 7q22.1
012 XG XG Glycoprotein Xp22.33
013 Scianna SC Glycoprotein 1p34.2
014 Dombrock DO Glycoprotein ( fixed to cell membrane by GPI , or glycosyl-phosphatidyl-inositol ) 12p12.3
015 Colton CO Aquaporin 1 . Main antigens Co ( a ) and Co ( b ) 7p14.3
016 Landsteiner-Wiener LW Protein ( member of the immunoglobulin superfamily ) 19p13.2
017 Chido CH C4A C4B ( complement fractions ) 6p21.3
018 Hh H Carbohydrate ( fucose residue ) 19q13.33
019 XK XK Glycoprotein Xp21.1
020 Gerbich GE GPC / GPD ( Glycophorins C and D ) 2q14.3