COVID-19 related Engineering Data - FTLOG Data-Only Please! - Page 1
Forum section: electronics / projects

author: pipe2null
author_rank: Regular Contributor
timestamp: March 31, 2020, 08:38:54 pm
content: The intention of this thread is to post harder to find COVID-19 related data that might be useful from an engineering perspective.This is a "Put data where your mouth is" kinda thing.Please do not post project-specific discussion here, there is enough Jerry-Springer-Grade controversy in a multitude of other threads already.I hope this topic might be respected as aSafe haven where tangible data reigns supreme. So, please put data where your mouth is or troll elsewhere. Seriously, no offense intended.Please include a short excerpt and/or context when appropriate.My contribution, for example:Some medical professionals have used SARS-CoV as a model for COVID-19 since formal studies of the new virus were unavailable and AFAIK remain unavailable. Attached is a professional study I found on ways to effectively kill the SARS virus that includes numbers and graphs that engineers might find useful. If you have more up-to-date information or find a similar study, please post! See attached PDF.Excerpt:2.3. UV light treatmentUltraviolet light (UV) treatment was performed on 2 ml aliquots of virus (volume depth = 1 cm) in 24-well plates (Corning Inc., Corning, NY). The UV light source (Spectronics Corporation, Westbury, NY) was placed above the plate, at a distance of 3 cm from the bottom of the wells containing the virus samples. At 3 cm our UVC light source (254 nm) emitted 4016 μW/cm2 (where μW = 10−6 J/s)...3.1. Effect of radiation on the infectivity of SARS-CoV... Exposure of virus to UVC light resulted in partial inactivation at 1 min with increasing efficiency up to 6 min (Fig. 1A), resulting in a 400-fold decrease in infectious virus. No additional inactivation was observed from 6 to 10 min. After 15 min the virus was completely inactivated to the limit of detection of the assay, which is ≤1.0 TCID50 (log10) per ml.2.5. Heat treatment of virusWe incubated 320μl aliquots of virus in 1.5 ml polypropylene cryotubes using a heating block to achieve three different temperatures (56, 65 and 75 ◦C).3.2. Effect of heat treatment on the infectivity of SARS-CoV...... At 65 ◦C, most of the virus was inactivated if incubated for longer than 4 min (Fig. 2B). Again, some infectious virus could still be detected close to the limit of detection for the assay, after 20 min at 65 ◦C. While virus was incompletely inactivated at 56 and 65 ◦C even at 60 min, it was completely inactivated at 75 ◦C in 45 min (Fig. 2C). Surprisingly, at both 56 and 65 ◦C the virus was inactivated at early time points but at 60 min a small amount of virus was detected.Related project thread(s) if applicable:(Will edit post later to link related discussion/project threads)Related open questions not effectively answered in this specific study:- What is the relationship between UVC intensity and required exposure time (for other intensity levels)?- Is UVC more/less/same as effective on water/air/aerosol/surface dwelling viruses?

author: profdc9
author_rank: Frequent Contributor
timestamp: April 01, 2020, 01:35:59 am
content: Consult this document in progresshttps://docs.google.com/document/d/193mt42jUR8PxuONUY4A6YZsyOOmy6Psg6BDme3rjai8/edit#heading=h.tcxzsexja88tIn particular,Evaluation of Five Decontamination Methods for Filtering Facepiece Respirators by Viscusi et alhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2781738/andInactivation of SARS Coronavirus by Means of Povidone-Iodine, Physical Conditions and Chemical Reagents by Kariwa et alhttps://www.karger.com/Article/FullText/89211but read over the document for the many references.

author: pipe2null
author_rank: Regular Contributor
timestamp: April 01, 2020, 06:59:16 pm
content: CDC and EPA recommended COVID-19 chemical disinfectants. Also includes required disinfectant contact times for each chemical.List N: Disinfectants for Use Against SARS-CoV-2https://www.epa.gov/pesticide-registration/list-n-disinfectants-use-against-sars-cov-2Warning: Some of those chemicals are pretty nasty, so probably a good idea to read the directions first...Attached is the complete list as of March 26, 2020.

author: pipe2null
author_rank: Regular Contributor
timestamp: April 01, 2020, 08:25:06 pm
content: Study on using UVC and bright light to kill viruses including SARS-CoV in blood bags/platelets/plasma. Might be useful if you are trying to use UVC to disinfect something but don't know required UVC source wattage or exposure time.Excerpt:"...In PCs, at half of the full UVC dose (0.1 J/cm2) SARS-CoV and CCHFV infectivity levels were below the [Limit Of Detection]"UVC Light dose (cumulative)Bag1 log10 TCID50/mlBag1 log10 RFBag2 log10 TCID50/mlBag2 log10 RFOriginal A05.8 +/- 0.36.0 +/- 0.20.05 J/cm22.7 +/- 0.33.13.0 +/- 0.43.00.1 J/cm2≤2.4≥3.4≤2.4≥3.4RF = log10A0 – log10An(R,reduction factor; A0, spiked total virus load before treatment; and An, total virus load after treatment)