Covid 19 Vaccine - Page 1
Forum section: electronics / general

author: SilverSolder
author_rank: Super Contributor
timestamp: March 17, 2020, 07:19:35 pm
content: How fast can the life sciences work?March 16, 2020SEATTLE (AP) — U.S. researchers gave the first shot to the first person in a test of an experimental coronavirus vaccine Monday -- leading off a worldwide hunt for protection even as the pandemic surges.https://www.wgbh.org/news/national-news/2020/03/16/coronavirus-vaccine-test-opens-as-us-volunteer-gets-1st-shot

author: vad
author_rank: Frequent Contributor
timestamp: March 17, 2020, 07:47:28 pm
content: Chief scientist on Trump’s task force said it will take 12-18 months. My hope, they will find a way to cut corners, and maybe we will see “deployable” vaccine by fall. They are already doing that, by going straight to phase 1 clinical trials, bypassing animal testing.

author: Bud
author_rank: Super Contributor
timestamp: March 17, 2020, 08:17:47 pm
content: Frankly, 18 months is what pretty much all other medical specialists are estimating , not only that genius in us government.

author: Stray Electron
author_rank: Super Contributor
timestamp: March 17, 2020, 08:22:39 pm
content: 12 to 18 months is an incredibly fast time to market for anything medical in the US. Usually the time is measured in decades. As the previous poster pointed out, they're skipping animal testing and have started human testing. But it will take months to see which treatments are effective and which aren't. They hope to have those answers by about August or September. After that they think it will take 6 months to start manufacturing and probably another 6 months before they have enough doses to begin to inoculate large numbers of people.

author: vad
author_rank: Frequent Contributor
timestamp: March 17, 2020, 10:51:33 pm
content: Also note that influenza vaccine is reformulated twice a year. So obviously flu vac does not go through the 12-18 month long clinical trials and production cycle. Otherwise it will become obsolete, due to flu mutation, before vaccine is released.With economy at stake, bureaucrats may streamline their approval processes, and with government funding businesses may ramp up vaccine production capacity. Or maybe not...

author: SilverSolder
author_rank: Super Contributor
timestamp: March 17, 2020, 10:54:05 pm
content: Is it worth getting a regular flu shot? - is it possible to get ill with both regular flu and Covid 19 at the same time?

author: vad
author_rank: Frequent Contributor
timestamp: March 18, 2020, 01:04:19 am
content: Quote from: SilverSolder on March 17, 2020, 10:54:05 pmYes. Flu season is not over in the U.S., and tens of thousands die from it each year. If you are lucky enough you can get both at the same time.

author: DrG
author_rank: Super Contributor
timestamp: March 18, 2020, 03:38:22 am
content: Quote from: vad on March 17, 2020, 07:47:28 pmSo, not to be too picky, the test compound, mRNA-1273, has shown efficacy (or at least "promise") in animal models. What they might have skipped is the basic animal rule requiring toxicity testing, typically 28-day and GLP in at least two animal species.The clinical trial is for healthy normal volunteers - a simple dose-effect - Phase 1 safety. The effort can progress to Phase 2 (testing in a few folks with Covid-19) if that goes well.It is probably the case that the push will have many candidates (already) in testing in different countries....and like you, I hope something is a hit, and soon.https://www.nih.gov/news-events/news-releases/nih-clinical-trial-investigational-vaccine-covid-19-beginshttps://clinicaltrials.gov/ct2/show/NCT04283461?term=mrna-1273&draw=2&rank=1

author: SilverSolder
author_rank: Super Contributor
timestamp: March 19, 2020, 11:06:56 pm
content: I went and got a flu shot today. Apparently these things are about 50% effective in preventing getting the type(s) of flu they target. Given that we really, really don't want to have both Covid-19 and regular flu at the same time, this seems like a sensible risk reduction strategy.

author: mzzj
author_rank: Super Contributor
timestamp: March 19, 2020, 11:18:58 pm
content: Quote from: vad on March 17, 2020, 07:47:28 pmUmbrella corporation anyone?

author: DrG
author_rank: Super Contributor
timestamp: March 19, 2020, 11:19:25 pm
content: Quote from: SilverSolder on March 19, 2020, 11:06:56 pmI agree. Are you in the US? Did you get the quadrivalent or old fart booster (high dose trivalent) or ?

author: SilverSolder
author_rank: Super Contributor
timestamp: March 19, 2020, 11:52:50 pm
content: Quote from: DrG on March 19, 2020, 11:19:25 pmYes, east coast. - LOL I didn't know there were different ones. This is the first one I've had in a decade, so it is probably not a booster...

author: DrG
author_rank: Super Contributor
timestamp: March 20, 2020, 12:20:17 am
content: Quote from: SilverSolder on March 19, 2020, 11:52:50 pmYeah, there are. The quadrivalent protects against four strains. The high dose (old fart booster) is trivalent (protecting against three strains) but 4X the antigen as compared to normal trivalent. It was offered this season for old farts with the idea that their immune systems benefist from the increase and there is some evidence to suggest that seehttps://www.cdc.gov/flu/prevent/qa_fluzone.htmI asked because I had to make a case for the quadrivalent and they gave me what I asked for (although I had to put in writing that I specifically requested it). I just reasoned that I would rather be protected against for strains and, I would like to believe, that my immune system is fine. My guess is that the quadrivalent 4X will be available next season.

author: SilverSolder
author_rank: Super Contributor
timestamp: March 20, 2020, 12:25:19 am
content: Quote from: DrG on March 20, 2020, 12:20:17 amInteresting, so at what age to they switch from prescribing one over the other? - or do they take general health levels into account?

author: DrG
author_rank: Super Contributor
timestamp: March 20, 2020, 12:28:36 am
content: Quote from: SilverSolder on March 20, 2020, 12:25:19 amI believe that they use the universal 65 metric as constituting old fart class.That you are asking suggests that they probably gave you trivalent 1X and that you were not eligible for 4 X....but I could be wrong.

author: SilverSolder
author_rank: Super Contributor
timestamp: March 20, 2020, 12:51:57 am
content: Quote from: DrG on March 20, 2020, 12:28:36 amIt wasn't even discussed, it was just called a "flu shot"... I'm still (rapidly) approaching 60 so perhaps they defaulted to 4x.

author: jxjbsd
author_rank: Regular Contributor
timestamp: March 21, 2020, 11:40:43 am
content: China's new crown vaccine has been injected into the human body for the first batch of experiments 108 volunteershttps://tech.sina.com.cn/roll/2020-03-21/doc-iimxyqwa2231078.shtml

author: SilverSolder
author_rank: Super Contributor
timestamp: March 21, 2020, 06:53:54 pm
content: I calculated the number of known infections on March 20 as a percentage of the country's population. Listed below, down to 0.001%PctInfected Country------------ --------0.449753% San Marino0.125156% Vatican City0.112282% Iceland0.100267% Dominican Republic0.096721% Andorra0.095486% Liechtenstein0.078841% Luxembourg0.078052% Italy0.065405% Switzerland0.052921% Spain0.036888% Norway0.030014% Austria0.028721% Monaco0.024426% Belgium0.023870% Germany0.023583% Iran0.023168% Denmark0.021304% Estonia0.019309% Bahrain0.019006% France0.017631% Brunei0.017212% Netherlands0.017108% Qatar0.016993% South Korea0.016284% Slovenia0.015861% Sweden0.013878% Ireland0.012967% Malta0.009925% Portugal0.008563% Cyprus0.008453% Czech Rep0.008141% Finland0.008121% Guam0.007684% Israel0.007170% Seychelles0.006750% Singapore0.006503% Latvia0.006040% UK0.006001% US0.005797% China0.005410% Armenia0.004741% Panama0.004616% Greece0.004163% Australia0.004121% Croatia0.003659% North Macedonia0.003615% Malaysia0.003597% Kuwait0.003566% Greenland0.003469% Maldives0.003126% Uruguay0.002863% Canada0.002726% Bosnia and Herzegovina0.002593% Lebanon0.002511% Slovakia0.002470% Lithuania0.002461% Moldova0.002445% Albania0.002441% Ecuador0.002271% Chile0.002250% Montenegro0.002234% Costa Rica0.002140% Serbia0.002090% Barbados0.002029% Bulgaria0.001916% Guyana0.001587% Romania0.001416% United Arab Emirates0.001262% Georgia0.001144% Poland0.001119% St Lucia0.001115% Oman0.001106% Mauritius0.001054% Hungary0.001046% New Zealand0.001038% The Bahamas0.001037% Antigua and Barbuda0.001005% Saudi Arabia

author: SiliconWizard
author_rank: Super Contributor
timestamp: March 21, 2020, 07:01:43 pm
content: The Iceland figure looks odd - as you don't expect a whole lot of traveling to and from there - although probably just explained by the fact this is a very small population (~360k), so obviously any case will contribute a lot more to the percentage.

author: SilverSolder
author_rank: Super Contributor
timestamp: March 21, 2020, 07:07:22 pm
content: Quote from: SiliconWizard on March 21, 2020, 07:01:43 pmIceland has a lot of tourism, and relatively few tourist destinations... and a lot of people working in the industry. People (including me!) use Iceland as a stop-over on the way between America and Europe. I can totally see how this could happen.The other factor is - how much is each country actually testing? They will "look good" if they don't test as much as the best.