COVID-19 spike protein receptor probing via graphene bio sensor - Page 1
Forum section: electronics / general

author: cdev
author_rank: Super Contributor
timestamp: May 10, 2020, 03:57:10 pm
content: Here is another working GrapheneFET COVID-19 bio sensorWhy aren't they mass producing this?https://arxiv.org/abs/2003.12529AbstractHere, in an effort towards facile and fast screening/diagnosis of novel coronavirusdisease 2019 (COVID-19), we combined the unprecedently sensitive graphene field-effect transistor (Gr-FET) with highly selective antibody-antigen interaction to developa coronavirus immunosensor. The Gr-FET immunosensors can rapidly identify (about2 mins) and accurately capture the COVID-19 spike protein S1 (which contains areceptor binding domain, RBD) at a limit of detection down to 0.2 pM, in a real-timeand label-free manner. Further results ensure that the Gr-FET immunosensors can bepromisingly applied to screen for high-affinity antibodies (with binding constant up to2×10 11 M -1 against the RBD) at concentrations down to 0.1 pM. Thus, our developedelectrical Gr-FET immunosensors provide an appealing alternative to address the earlyscreening/diagnosis as well as the analysis and rational design of neutralizing-antibodylocking methods of this ongoing public health crisis."

author: Syntax Error
author_rank: Frequent Contributor
timestamp: May 10, 2020, 04:33:26 pm
content: Tweet Elon Musk

author: SiliconWizard
author_rank: Super Contributor
timestamp: May 10, 2020, 06:31:27 pm
content: Which foundry is currently offering graphene FETs on a large scale?

author: Rick Law
author_rank: Super Contributor
timestamp: May 10, 2020, 07:18:05 pm
content: Quote from: cdev on May 10, 2020, 03:57:10 pmDon't take this as argumentative. I do mean this simply as a question:How do you know they are not doing this already?With so many new things popping up so quickly, something along that line may be in progress already. Actually, with so many balls in the air, I think they are jamming up the pipe-line already. I hope they have a good analytical team doing the prioritization. So far, the IHME model and the Imperial College model used by the experts both have been at best no-good and at worst darn-awful.IHME model has been very disappointing to me personally. I used and quoted their number here on a reply. But they were no where near reality looking merely as close as just a few days ahead. I can come up with a function to fit nicely to any actual curve, but the point of a model is how it extrapolates to the future so we can use it to guide our actions. At that, current models failed miserably.At this stage (as I understand it), we need anti-body (potential/actual immunity) detection, infection detection, and treatment. Personally, I would focus my effort on treatment as death is almost always irreversible. Say if there is good treatment that keeps the victim alive and limits the health damage, it really doesn't matter how fast and wide it spread. When it gets to the point of "Pop a pill, and off you go back to work with nothing more than a minor headache", even if the whole world is infected, damage is minor then.

author: cdev
author_rank: Super Contributor
timestamp: May 10, 2020, 08:00:12 pm
content: "graphena" seems to be selling a graphene FET base that can be made into an array of biosensors, I am gathering.https://www.graphenea.com