pure encapsulations motilpro | hypoallergenic dietary supplement to promote healthy gut motility* | 180 capsules pure encapsulations motilpro supports serotonergic and cholinergic neurotransmission in the g.i. tract. 5-htp is absorbed by enterochromaffin cells in the epithelium, in which it is decarboxylated to serotonin using pyridoxal 5' phosphate as a cofactor. 5-htp stimulates enteric neurons through activation of 5ht4 receptors. ginger modulates serotonin signaling by additional 5ht4 stimulation and by binding type 3 (5ht3) receptors in the enteric nervous system and brain stem, supporting gastric emptying, intestinal transit, healthy visceral sensation and upper g.i. comfort. acetyl-l-carnitine supports autonomic neuronal health and contributes acetyl groups for the synthesis of acetylcholine, supporting neurotransmission of signals to encourage healthy motility.*