integrative therapeutics berberine - metabolic and healthy blood sugar support supplement with berberine hcl* - for men and women - gluten free and vegan - 60 500 mg capsules integrative therapeutics berberine offers metabolic support for glucose and lipid metabolism.* it also supports healthy blood sugar and insulin levels already within a normal range.* berberine supports healthy lipid metabolism and cholesterol homeostasis.* it can activate an important metabolic enzyme known as adenosine monophosphate-activated protein kinase (ampk), a central regulator of cellular energy homeostasis and can decrease cholesterol and triglyceride synthesis by activating ampk. in addition to supporting lipid metabolism, berberine supports healthy glucose metabolism and blood sugar management already within a normal range.* berberine can support healthy glucose regulation through promoting glucose uptake in cells via glut4 translocation.*