pure encapsulations cortisol calm | supplement to support relaxation and restful sleep during times of occasional stress* | 120 capsules pure encapsulations cortisol, released in response to stress, is mainly produced by the adrenal cortex. intra-abdominal adipocytes also produce cortisol. in a recent study, sensoril ashwagandha extract promoted relaxation and maintained healthy cortisol response. subjects in this randomized, double-blind, placebo-controlled study reported support for healthy sleep, a positive outlook, and cognitive function. the effects were most pronounced for subjects taking 500 mg per day compared to lesser doses. rhodiola and magnolia may also maintain healthy adrenal cortisol activity and offer support for occasional stress, a positive outlook, and well-being. l-theanine supports normal brain alpha-wave activity, helping calm the sympathetic nervous system for a relaxing effect. recent research suggests that maintaining healthy vitamin d levels supports normal cortisol production within abdominal adipocytes.