hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
5α-Reductase
5α-Reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in steroid metabolism. They participate in three metabolic pathways: bile acid biosynthesis, androgen and estrogen metabolism.  There are three isozymes of 5α-reductase encoded by the genes SRD5A1, SRD5A2, and SRD5A3.

5α-Reductases catalyze the following generalized chemical reaction:

a 3-oxo-5α-steroid + acceptor ⇌ a 3-oxo-Δ4-steroid + reduced acceptor

Where a 3-oxo-5α-steroid and acceptor are substrates, and a corresponding 3-oxo-Δ4-steroid and the reduced acceptor are products. An instance of this generalized reaction that 5α-reductase type 2 catalyzes is:

where dihydrotestosterone is the 3-oxo-5α-steroid, NADP+ is the acceptor and testosterone is the 3-oxo-Δ4-steroid and NADPH the reduced acceptor.

CYP17A1
Cytochrome P450 17A1 (steroid 17α-monooxygenase, 17α-hydroxylase, 17-alpha-hydroxylase, 17,20-lyase, 17,20-desmolase) is an enzyme of the hydroxylase type that in humans is encoded by the CYP17A1 gene on chromosome 10. It is ubiquitously expressed in many tissues and cell types, including the zona reticularis and zona fasciculata (but not zona glomerulosa) of the adrenal cortex as well as gonadal tissues. It has both 17α-hydroxylase and 17,20-lyase activities, and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. More specifically, the enzyme acts upon pregnenolone and progesterone to add a hydroxyl (-OH) group at carbon 17 position (C17) of the steroid D ring (the 17α-hydroxylase activity, EC 1.14.14.19), or acts upon 17α-hydroxyprogesterone and 17α-hydroxypregnenolone to split the side-chain off the steroid nucleus (the 17,20-lyase activity, EC 1.14.14.32).
Methyl group
In organic chemistry, a methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms, having chemical formula CH3 (whereas normal methane has the formula CH4). In formulas, the group is often abbreviated as Me. This hydrocarbon group occurs in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, bonded to the rest of the molecule by a single covalent bond (−CH3), it can be found on its own in any of three forms: methanide anion (CH−3), methylium cation (CH+3) or methyl radical (CH•3). The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed.

Dimethylamine
Dimethylamine is an organic compound with the formula (CH3)2NH. This secondary amine is a colorless, flammable gas with an ammonia-like odor. Dimethylamine is commonly encountered commercially as a solution in water at concentrations up to around 40%. An estimated 271,000 tons were produced in 2005.
2016 Brunei Super League
The 2016 Brunei Super League (also known as the DST Super League for sponsorship reasons) was the 4th season of the Brunei Super League, the top Bruneian professional league for association football clubs, since its establishment in 2012. The season began on 12 March 2016 and concluded on 30 September 2016.

MS ABDB came into the season as defending champions of the 2015 season. Kota Ranger and Kasuka entered as the two promoted teams from the Premier League. NFABD concluded the league after only one round, which meant that MS ABDB retained the title with seven wins out of nine.

2018–19 Brunei Super League
The 2018–19 Brunei Super League is the 6th season of the Brunei Super League, the top Bruneian professional league for association football clubs, since its establishment in 2012. The season began on 26 October 2018.
Paterson, New Jersey
Paterson (English pronunciation: /ˈpætɚsən/ ⓘ) is the largest city in and the county seat of Passaic County, in the U.S. state of New Jersey. As of the 2020 United States census, Paterson was the state's third-most-populous municipality, with a population of 159,732, an increase of 13,533 (+9.3%) from the 2010 census count of 146,199, which in turn reflected a decline of 3,023 (-2.0%) from the 149,222 counted in the 2000 census. The Census Bureau's Population Estimates Program calculated a population of 156,452 for 2023, making it the 168th-most populous municipality in the nation.

A prominent mill town within the New York–New Jersey metropolitan area, Paterson has been known as Silk City for its once-dominant role in silk production during the latter half of 19th century. It has since evolved into a major destination for Hispanic immigrants as well as for immigrants from Turkey, the Arab world, and South Asia. Paterson has the nation's second-largest per capita Muslim population.

New Jersey Department of Transportation
The New Jersey Department of Transportation (NJDOT) is the agency responsible for transportation issues and policy in New Jersey, including maintaining and operating the state's highway and public road system, planning and developing transportation policy, and assisting with rail, freight, and intermodal transportation issues. It is headed by the Commissioner of Transportation. The present acting commissioner is Francis K. O'Connor.
La (cuneiform)
The cuneiform sign for la (𒆷), and also in the Epic of Gilgamesh the sumerogram LA-(capital letter (majuscule), is a common-use sign for the Epic and for the 1350 BC Amarna letters. It is used for syllabic la, and also for alphabetic l, or a.

Ki (cuneiform)
Cuneiform KI (Borger 2003 nr. 737; U+121A0 𒆠) is the sign for "earth". 
It is also read as GI5, GUNNI (=KI.NE) "hearth", KARAŠ (=KI.KAL.BAD) "encampment, army", KISLAḪ (=KI.UD) "threshing floor", and SUR7 (=KI.GAG). In Akkadian orthography, it functions as a determiner for toponyms and has the syllabic values gi, ge, qi, and qe. Besides its phonetic value it also serves as determiner or "Sumerogram" marking placenames.

As a determiner, KI corresponds to Akkadian itti,

Cuneiform ki is used for syllabic "ki", and also for alphabetic "k", and alphabetic i. It has additional consonant usage for "q", instead of "k", and also "e", "é", and "í" for vowel "i". Its usage numbers from the Epic of Gilgamesh are as follows: ke-(9), ki-(291), qé-(18), qí-(62), and KI-(288).
Israeli Basketball Premier League
Ligat HaAl (Hebrew: ליגת העל, lit., Supreme League or Premier League), or the Israeli Basketball Premier League, is a professional basketball league in Israel and the highest level of basketball in the country. The league's name is abbreviated as either BSL (Basketball Super League) or ISBL (Israeli Basketball Super League). For sponsorship reasons, the league is also referred to as Ligat Winner Sal (Hebrew: ליגת ווינר סל), lit. Winner Basket League, with "Winner" being the name of a game operated by the league's primary sponsor, Toto Winner.

The league is run by the Israeli Basketball Super League Administration Ltd.

Marcus Carr
Marcus Joshua Carr (born June 6, 1999) is a Canadian professional basketball player for Würzburg Baskets of the German Basketball Bundesliga (BBL). He played college basketball for the Pittsburgh Panthers, the Minnesota Golden Gophers and the Texas Longhorns.
Christian Gottfried Daniel Nees von Esenbeck
Christian Gottfried Daniel Nees von Esenbeck (14 February 1776 – 16 March 1858) was a prolific German botanist, physician, zoologist, and natural philosopher. He was a contemporary of Goethe and was born within the lifetime of Linnaeus. He described approximately 7,000 plant species (almost as many as Linnaeus himself). His last official act as president of the German Academy of Natural Scientists Leopoldina was to admit Charles Darwin as a member. He was the author of numerous monographs on botany and zoology and majority of his best-known works deal with fungi. The standard author abbreviation Nees is used to indicate this person as the author when citing a botanical name.

Christian Friedrich Lessing
Christian Friedrich Lessing (10 August 1809 – 13 March 1862) was a German botanist who was a native of Groß Wartenberg, Niederschlesien. He was a brother to painter Carl Friedrich Lessing (1808–1880), and a grandnephew of poet Gotthold Ephraim Lessing (1729–1781).

Lessing was a botanical authority on the plant family Asteraceae, and in 1832 published an influential treatise on Asteraceae called Synopsis generum Compositarum. He performed extensive botanical research in Siberia. In 1862 he was buried in Trinity Cemetery, in the Siberian city of Krasnoyarsk.

The plant genus Lessingia from the family Asteraceae is named in honor of Christian Friedrich, Karl Friedrich and Gotthold Ephraim Lessing.
New Gate
The New Gate (Arabic: باب الجديد Bāb ij-Jdïd; Hebrew: השער החדש HaSha'ar HeChadash) is the newest of the gates of the Old City of Jerusalem. It was built in 1889 by the Ottomans under the directorship of the French consul and Franciscan brotherhood monkship order to provide direct access between the Christian Quarter and the new neighborhoods then going up outside the walls. The arched gate is decorated with crenelated stonework. The New Gate was built at the highest point of the present wall, at 790 metres (2,590 ft) above sea level.

Jaffa Gate
Jaffa Gate (Hebrew: שער יפו, romanized: Sha'ar Yafo; Arabic: باب الخليل, romanized: Bāb al-Khalīl, "Hebron Gate") is one of the seven main open gates of the Old City of Jerusalem.

The name Jaffa Gate is currently used for both the historical Ottoman gate from 1538, and for the wide gap in the city wall adjacent to it to the south. The old gate has the layout of a medieval gate tower with an L-shaped entryway, which was secured at both ends (north and east) with heavy doors.

The breach in the wall was created in 1898 by the Ottoman authorities in order to allow German emperor Wilhelm II to enter the city triumphally. The breach and the ramp leading to it now allow cars to access the Old City from the west.

The L-shape of the historical gateway was a classical defensive measure designed to slow oncoming attackers, with its outer gate oriented in the direction of Jaffa Road, from which travellers including pilgrims arrived at the end of their journey from the port of Jaffa.
Juan José Linz
Juan José Linz Storch de Gracia (24 December 1926 – 1 October 2013) was a German-born Spanish sociologist and political scientist specializing in comparative politics. From 1961 he was Sterling Professor Emeritus of Sociology and Political Science at Yale University and later also an honorary member of the Scientific Council at the Juan March Institute. He is best known for his work on authoritarian political regimes and democratization.

Examples of totalitarian regimes
Within the academic context, the concept of totalitarianism has been applied to several regimes, with much debate and disagreements, most notably about the Soviet Union, Fascist Italy, Nazi Germany, the Empire of Japan under Kokkashugi, Francoist Spain, and Ba'athist Iraq. Totalitarian regimes are usually distinguished from authoritarian regimes in the sense that totalitarianism represents an extreme version of authoritarianism. Authoritarianism primarily differs from totalitarianism in that social and economic institutions exist that are not under governmental control.
Río Negro Department
Río Negro Department (Spanish: Departamento de Río Negro, Spanish pronunciation: [ˈri.o ˈneɣɾo]) is a department of the northwestern region of Uruguay. It has an area of 9,282 km2 (3,584 sq mi) and a population of 57,334. Its capital is Fray Bentos. It borders Paysandú Department to the north, Tacuarembó Department to the east, Durazno Department to the southeast, Soriano Department to the south and has the Río Uruguay flowing at its west, separating it from Argentina.

Artigas Department
Artigas Department (Spanish: Departamento de Artigas) is the northernmost department of Uruguay. Its capital is the city of Artigas, which borders the Brazilian city of Quaraí. Artigas Department has an area of 11,928 square kilometres (4,605 sq mi), making it the fifth largest in the country. The population is 77,487 inhabitants, according to the 2023 census.

It is bordered on the north and east by Brazil, from which it is separated by the Cuareim River. To the south, Artigas Department borders on Salto Department, and to the west is Argentina, from which it is separated by the Uruguay River. Artigas is the only Uruguayan department that borders two other countries.

The department and its capital city are named after José Gervasio Artigas (1764–1850), leader of the Orientales (inhabitants of the Banda Oriental, the Eastern bank of the Uruguay River) during Uruguay's wars of independence.
Corcoran Gallery of Art
The Corcoran Gallery of Art was an art museum in Washington, D.C., at the location where the Corcoran School of the Arts and Design, a part of the George Washington University, is now.

Founded in 1869 by philanthropist William Wilson Corcoran, the gallery was one of the earliest public art museums in the United States.  It held an important collection that became concentrated in American art. In 1890, it started its art school. Its Beaux-Arts style building on The Ellipse was opened in 1897. Due to a prolonged economic shortfall, the Gallery failed in October 2014; pursuant to its founding charter, its art school and building transferred to GWU and the 19,456 works in its collection were distributed to other public museums and institutions in Washington, D.C., primarily the National Gallery of Art.

Memorial Art Gallery
The Memorial Art Gallery is a civic art museum in Rochester, New York. Founded in 1913, it is part of the University of Rochester and occupies the southern half of the University's former Prince Street campus.  It is a focal point of fine arts activity in the region and hosts the biennial Rochester-Finger Lakes Exhibition and the annual Clothesline Festival.
2021 Campeonato Pernambucano
The 2021 Campeonato Pernambucano da Série A1 was the 107th edition of the state championship of Pernambuco organized by FPF. The championship began on 24 February and ended on 23 May. Salgueiro were the defending champions but they were eliminated in the semi-finals.

The finals were contested in two-legged home-and-away format between Náutico and Sport. Tied 2–2 on aggregate, Náutico won 5–3 on penalties, winning the tournament for the 23rd time. As champions, Náutico qualified for 2022 Copa do Brasil and 2022 Copa do Nordeste. The runners-up, Sport also qualified for 2022 Copa do Brasil and 2022 Copa do Nordeste (via RNC), while Salgueiro, the best placed team in the first stage not already qualified, gained the third berth for 2022 Copa do Brasil.

2022 Campeonato Pernambucano
The 2022 Campeonato Pernambucano (officially the Pernambucano Betsson 2022 for sponsorship reasons) was the 108th edition of the state championship of Pernambuco organized by FPF. The championship began on 22 January and ended on 30 April 2022.

In the first stage, Sete de Setembro had three points deducted for fielding the ineligible player Bililiu in the match Sete de Setembro v Náutico played on 1 February 2022 (2nd round).

The finals were contested in two-legged home-and-away format between the defending champions Náutico and Retrô. Tied 1–1 on aggregate, Náutico won 4–2 on penalties, winning the tournament for the 24th time. As champions, Náutico qualified for 2023 Copa do Brasil and 2023 Copa do Nordeste. The runners-up, Retrô qualified for 2023 Copa do Brasil and 2023 Copa do Nordeste qualification, while Santa Cruz, the best placed team in the first stage not already qualified, gained the third berth for 2023 Copa do Brasil.
The Game Awards 2016
The Game Awards 2016 was an award show that honored the best video games of 2016. It was produced and hosted by Geoff Keighley at the Microsoft Theater in Los Angeles on December 1, 2016, and was live streamed across several platforms. During the event, Overwatch won Game of the Year, Blizzard Entertainment won Best Studio, and game designer Hideo Kojima was honored with the Industry Icon Award.

13th British Academy Games Awards
The 13th British Academy Video Game Awards awarded by the British Academy of Film and Television Arts, is an award ceremony that was held on 6 April 2017 at Tobacco Dock. The ceremony honoured achievement in video gaming in 2016 and was hosted by Danny Wallace.
Elegant fat-tailed mouse opossum
The elegant fat-tailed mouse opossum (Thylamys elegans), also known as the Chilean mouse opossum, is an opossum from central Chile. The type species of Thylamys, it was first described by English naturalist George Robert Waterhouse in 1839. This medium-sized opossum is characterized by black rings around the eyes, white limbs, gray to light brown coat, lighter flanks and underbelly and a thick 12.7–14.6 centimetres (5.0–5.7 in) long tail covered with hairs. It is crepuscular (active mainly around twilight) and lives in nests in tree hollows or under rocks and roots. This opossum feeds mainly on arthropods and larvae apart from fruits. Litter size is typically between 11 and 13. The elegant fat-tailed opossum can occur in a variety of habitats – from cloud forests to chaparrals. The IUCN classifies the opossum as least concern.

Chacoan gracile opossum
The chacoan gracile opossum (Cryptonanus chacoensis) is a species of opossum in the family Didelphidae. It is native to Argentina, Brazil and Paraguay.  Its habitat is seasonally flooded grasslands and forests in and near the Gran Chaco.

The red-bellied gracile opossum (Cryptonanus ignitus), previously thought to have been extinct since 1962, has since been reevaluated as synonymous with the chacoan gracile opossum, as several specimens of C. chacoensis have been discovered that display similar coloration to C. ignitus.
Kapitänleutnant
Kapitänleutnant, short: KptLt/in lists: KL, (English: captain lieutenant or lieutenant captain) is an officer grade of the captains' military hierarchy group (German: Hauptleute) of the modern German Bundeswehr. The rank is rated OF-2 in NATO, and equivalent to Hauptmann in the Heer and Luftwaffe. It is grade A11 or A12 in the pay rules of the Federal Ministry of Defence.

The rank first appeared in the German Empire and continued in use through the Weimar Republic and into the Third Reich.

Walther Schwieger
Kapitänleutnant Wilhelm Otto Walther Schwieger (7 April 1885 – 5 September 1917) was a German military officer. He was a U-boat commander in the Imperial German Navy (Kaiserliche Marine) during First World War. In 1915, he sank the passenger liner RMS Lusitania with the loss of 1,199 lives.
16S ribosomal RNA
16S ribosomal RNA (or 16S rRNA) is the RNA component of the 30S subunit of a prokaryotic ribosome (SSU rRNA). It binds to the Shine-Dalgarno sequence and provides most of the SSU structure.

The genes coding for it are referred to as 16S rRNA genes and are used in reconstructing phylogenies, due to the slow rates of evolution of this region of the gene. Carl Woese and George E. Fox were two of the people who pioneered the use of 16S rRNA in phylogenetics in 1977. Multiple sequences of the 16S rRNA gene can exist within a single bacterium.

Phylum
In biology, a phylum (/ˈfaɪləm/; pl.: phyla) is a level of classification, or taxonomic rank, that is below kingdom and above class. Traditionally, in botany the term division has been used instead of phylum, although the International Code of Nomenclature for algae, fungi, and plants accepts the terms as equivalent. Depending on definitions, the animal kingdom Animalia contains about 32 phyla, the plant kingdom Plantae contains about 14 phyla, and the fungus kingdom Fungi contains about eight phyla. Current research in phylogenetics is uncovering the relationships among phyla within larger clades like Ecdysozoa and Embryophyta.
Tugboat
A tugboat or tug is a marine vessel that manoeuvres other vessels by pushing or pulling them, with direct contact or a tow line. These boats typically tug ships in circumstances where they cannot or should not move under their own power, such as in crowded harbors or narrow canals, or cannot move at all, such as barges, disabled ships, log rafts, or oil platforms. Some are ocean-going, and some are icebreakers or salvage tugs. Early models were powered by steam engines, which were later superseded by diesel engines. Many have deluge gun water jets, which help in firefighting, especially in harbours.

Depot ship
A depot ship is an auxiliary ship used as a mobile or fixed base for submarines, destroyers, minesweepers, fast attack craft, landing craft, or other small ships with similarly limited space for maintenance equipment and crew dining, berthing and relaxation. Depot ships may be identified as tenders in American English. Depot ships may be specifically designed for their purpose or be converted from another purpose.
Chet Baker
Chesney Henry "Chet" Baker Jr. (December 23, 1929 – May 13, 1988) was an American jazz trumpeter and vocalist. He is known for major innovations in cool jazz that led him to be nicknamed the "Prince of Cool".

Baker earned much attention and critical praise through the 1950s, particularly for albums featuring his vocals: Chet Baker Sings (1954) and It Could Happen to You (1958). Jazz historian Dave Gelly described the promise of Baker's early career as "James Dean, Sinatra, and Bix, rolled into one". His well-publicized drug habit also drove his notoriety and fame. Baker was in and out of jail frequently before enjoying a career resurgence in the late 1970s and 1980s.

John Abercrombie (guitarist)
John Laird Abercrombie (December 16, 1944 – August 22, 2017) was an American jazz guitarist. His work explored jazz fusion, free jazz, and avant-garde jazz. Abercrombie studied at Berklee College of Music in Boston, Massachusetts. He was known for his understated style and his work with organ trios.
Gerald Regan
Gerald Augustine Paul Regan PC QC ECNS (February 13, 1928 – November 26, 2019) was a Canadian politician (as federal MP and later as Nova Scotia MLA), who served as the 19th premier of Nova Scotia from 1970 to 1978.

1974 Nova Scotia general election
The 1974 Nova Scotia general election was held on 2 April 1974 to elect members of the 51st House of Assembly of the Province of Nova Scotia, Canada. It was won by the Liberal Party.

Most of its MLAs were elected in single-member district using first past the post voting but some, such as in Colchester and Yarmouth, were elected in two-seat districts using plurality block voting.
Term logic
In logic and formal semantics, term logic, also known as traditional logic, syllogistic logic or Aristotelian logic, is a loose name for an approach to formal logic that began with Aristotle and was developed further in ancient history mostly by his followers, the Peripatetics. It was revived after the third century CE by Porphyry's Isagoge.

Term logic revived in medieval times, first in Islamic logic by Alpharabius in the tenth century, and later in Christian Europe in the twelfth century with the advent of new logic, remaining dominant until the advent of predicate logic in the late nineteenth century.

However, even if eclipsed by newer logical systems, term logic still plays a significant role in the study of logic. Rather than radically breaking with term logic, modern logics typically expand it.

Validity (logic)
In logic, specifically in deductive reasoning, an argument is valid if and only if it takes a form that makes it impossible for the premises to be true and the conclusion nevertheless to be false. It is not required for a valid argument to have premises that are actually true, but to have premises that, if they were true, would guarantee the truth of the argument's conclusion. Valid arguments must be clearly expressed by means of sentences called well-formed formulas (also called wffs or simply formulas).

The validity of an argument can be tested, proved or disproved, and depends on its logical form.