hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Genetic hitchhiking
Genetic hitchhiking, also called genetic draft or the hitchhiking effect, is when an allele changes frequency not because it itself is under natural selection, but because it is near another gene that is undergoing a selective sweep and that is on the same DNA chain. When one gene goes through a selective sweep, any other nearby polymorphisms that are in linkage disequilibrium will tend to change their allele frequencies too. Selective sweeps happen when newly appeared (and hence still rare) mutations are advantageous and increase in frequency. Neutral or even slightly deleterious alleles that happen to be close by on the chromosome 'hitchhike' along with the sweep. In contrast, effects on a neutral locus due to linkage disequilibrium with newly appeared deleterious mutations are called background selection. Both genetic hitchhiking and background selection are stochastic (random) evolutionary forces, like genetic drift.

Regulation of transcription in cancer
Generally, in progression to cancer, hundreds of genes are silenced or activated.  Although silencing of some genes in cancers occurs by mutation, a large proportion of carcinogenic gene silencing is a result of altered DNA methylation (see DNA methylation in cancer).  DNA methylation causing silencing in cancer typically occurs at multiple CpG sites in the CpG islands that are present in the promoters of protein coding genes.

Altered expressions of microRNAs also silence or activate many genes in progression to cancer (see microRNAs in cancer).  Altered microRNA expression occurs through hyper/hypo-methylation of CpG sites in CpG islands in promoters controlling transcription of the microRNAs.

Silencing of DNA repair genes through methylation of CpG islands in their promoters appears to be especially important in progression to cancer (see methylation of DNA repair genes in cancer).
Hideki Suzuki
Hideki Suzuki (鈴木 秀樹, Suzuki Hideki; born February 18, 1980) is a Japanese professional wrestler and catch wrestler signed to All Japan Pro Wrestling.

Trained by Billy Robinson, Suzuki started his career with the Inoki Genome Federation (IGF) promotion in 2008. In 2014, he left IGF to become a freelancer, starting to work for promotions such as Big Japan Pro Wrestling (BJW), Pro Wrestling Zero1 (Zero1) and Wrestle-1 (W-1). He is a former two-time BJW World Strong Heavyweight Champion, a former one-time Zero1 World Heavyweight, NWA United National Heavyweight, Wrestle-1 Champion and NWA Intercontinental Tag Team Champion. In 2017, Fighting TV Samurai named Suzuki the MVP in Japanese independent wrestling. In 2021, Suzuki signed with WWE, where he performed on the NXT brand under the ring name Hachiman as a member of Diamond Mine, and also worked as a coach at the WWE Performance Center.

Daga (wrestler)
Miguel Ángel Olivo Castro (born June 19, 1988) is a Mexican professional wrestler better known by the ring name Daga. He is signed to Pro Wrestling Noah. He previously performed for Lucha Libre AAA Worldwide, where he was a former AAA Latin American Champion and AAA World Cruiserweight Champion. He is best known for his time with Lucha Underground and Impact Wrestling.
President of Guyana
The president of Guyana is the head of state and the head of government of Guyana, as well as the commander-in-chief of the armed forces of the Republic, according to the Constitution of Guyana. The president is also the chancellor of the Orders of Guyana. Concurrent with his constitutional role as commander-in-chief of the Armed Forces, the president does not appoint a separate minister of defence. That portfolio is held by the president who fulfils all responsibilities designated to a minister of defence under the Defence Act.

Order of Excellence of Guyana
The Order of Excellence of Guyana is the highest national award of Guyana.  Established in 1970 under the Constitution of the Orders of Guyana, it is limited to 25 living citizens of Guyana. This is the highest award of the state and is given to citizens of Guyana for distinction and eminence in the field of human endeavor which is of either national or international significance and importance. Any distinguished citizen of another country who has rendered valued service to Guyana or whom the state wishes to honour for any reason, may be given an honorary award.
Pasargadae
Pasargadae (/pəˈsɑːrɡədi/; from Pāθra-gadā, lit. 'protective club'  or 'strong club'; Persian: پاسارگاد, romanized: Pāsārgād) was the capital of the Achaemenid Empire under Cyrus the Great (559–530 BC), located just north of the town of Madar-e-Soleyman and about 90 kilometres (56 mi) to the northeast of the city of Shiraz. It is one of Iran's UNESCO World Heritage Sites. It is considered to be the location of the Tomb of Cyrus, a tomb previously attributed to Madar-e-Soleyman, the "Mother of Solomon". It is a national tourist site administered by the Iranian culture of world heritage.

Persis
Persis, also called Persia proper, is a historical region in south-western Iran, roughly corresponding with Fars province. Iranian speaking peoples, also known as Iranic speaking peoples, are thought to have initially migrated either from Central Asia or, more probably, from the north through the Caucasus giving rise to the ethnic group later known as Persians. They would then have migrated to the current region of Persis in the early 1st millennium BC.
National Firearms Act
The National Firearms Act (NFA), 73rd Congress, Sess. 2, ch. 757, 48 Stat. 1236 was enacted on June 26, 1934, and currently codified and amended as I.R.C. ch. 53. The law is an Act of Congress in the United States that, in general, imposes an excise tax on the manufacture and transfer of certain firearms and mandates the registration of those firearms. The NFA is also referred to as Title II of the federal firearms laws, with the Gun Control Act of 1968 ("GCA") as Title I.

All transfers of ownership of registered NFA firearms must be done through the National Firearms Registration and Transfer Record (the "NFA registry"). The NFA also requires that the permanent transport of NFA firearms across state lines by the owner must be reported to the Bureau of Alcohol, Tobacco, Firearms and Explosives (ATF). Temporary transports of some items, most notably suppressors (also referred to as silencers), do not need to be reported.

Stock (firearms)
A gunstock or often simply stock, the back portion of which is also known as a shoulder stock, a buttstock, or simply a butt, is a part of a long gun that provides structural support, to which the barrel, action, and firing mechanism are attached.  The stock also provides a means for the shooter to firmly brace the gun and easily aim with stability by being held against the user's shoulder when shooting the gun, and helps to counter muzzle rise by transmitting recoil straight into the shooter's body.

The tiller of a crossbow is functionally the equivalent of the stock on a gun.
Shepton Mallet
Shepton Mallet is a market town and civil parish in Somerset, England, some 16 miles (26 kilometres) southwest of Bath, 18 miles (29 kilometres) south of Bristol and 5 miles (8.0 kilometres) east of Wells. It had an estimated population of 10,810 in 2019. Mendip District Council was based there. The Mendip Hills lie to the north and the River Sheppey runs through the town, as does the route of the Fosse Way, the main Roman road between north-east and south-west England. There is evidence of Roman settlement. Its listed buildings include a medieval parish church. Shepton Mallet Prison was England's oldest, but closed in March 2013. The medieval wool trade gave way to trades such as brewing in the 18th century. It remains noted for cider production. It is the closest town to the Glastonbury Festival and nearby the Royal Bath and West of England Society showground.

Non-metropolitan district
Non-metropolitan districts, or colloquially "shire districts", are a type of local government district in England. As created, they are sub-divisions of non-metropolitan counties (colloquially shire counties) in a two-tier arrangement. Non-metropolitan districts with borough status are known as boroughs, able to appoint a mayor. Some shire counties, for example Cornwall, now have no sub-divisions so are a single non-metropolitan district.

Typically, a district will consist of a market town and its more rural hinterland. However, districts are diverse, with some being mostly urban (such as Dartford) and others more polycentric (such as Thurrock).
STS-41-B
STS-41-B was NASA's tenth Space Shuttle mission and the fourth flight of the Space Shuttle Challenger. It launched on February 3, 1984 and landed on February 11, 1984, after deploying two communications satellites. It was also notable for including the first untethered spacewalk.

Following STS-9, the flight numbering system for the Space Shuttle program was changed. Because the original successor to STS-9, STS-10, was canceled due to payload delays, the next flight, originally and internally designated STS-11, became STS-41-B as part of the new numbering system.

STS-47
STS-47 was  NASA's 50th Space Shuttle mission of the program, as well as the second mission of the Space Shuttle Endeavour. The mission mainly involved conducting experiments in life and material sciences inside Spacelab-J, a collaborative laboratory inside the shuttle's payload bay sponsored by NASA and the National Space Development Agency of Japan (NASDA). This mission carried Mamoru Mohri, the first Japanese astronaut aboard the shuttle, Mae Jemison, the first African-American woman to go to space, and the only married couple to fly together on the shuttle, Mark C. Lee and Jan Davis, which had been against NASA policy prior to this mission.
World Junior Heavyweight Championship (AJPW)
The Pacific Wrestling Federation (PWF) World Junior Heavyweight Championship (世界ジュニアヘビー級王座, Sekai Junia Hebī-kyū Ōza) is a professional wrestling world title in Japanese promotion All Japan Pro Wrestling, contested exclusively among junior heavyweight (<235 lb (107 kg)) wrestlers. It was created on July 31, 1986, when Hiro Saito defeated Brad Armstrong in a tournament final.

Voodoo Murders
Voodoo Murders (stylised in all capital letters, also stylised as VDM) were a professional wrestling stable who were best known as the main heel group in All Japan Pro Wrestling between 2005 and 2011, and 2022 to 2023. In 2013, the group was reformed in Diamond Ring and later performed primarily for Pro Wrestling ZERO1 in the stable's final years. The group, famously led by former Toryumon wrestler Taru, performed violent actions in their matches and displayed a lack of respect for their opponents.
Lou Grant (TV series)
Lou Grant is an American drama television series starring Ed Asner in the title role as a newspaper editor that aired on CBS from September 20, 1977, to September 13, 1982. The third spin-off (after Rhoda and Phyllis) of the American sitcom The Mary Tyler Moore Show, Lou Grant was created by James L. Brooks, Allan Burns, and Gene Reynolds.

Lou Grant won 13 Primetime Emmy Awards, including Outstanding Drama Series twice. Asner received the Primetime Emmy Award for Outstanding Lead Actor in a Drama Series in 1978 and 1980. In doing so, he became the first person to win an Emmy Award for both Outstanding Lead Actor in a Drama Series and Outstanding Supporting Actor in a Comedy Series for portraying the same character. Lou Grant also won two Golden Globe Awards, a Peabody Award, an Eddie Award, three awards from the Directors Guild of America, and two Humanitas Prizes.

Hardcastle and McCormick
Hardcastle and McCormick is an American action crime drama television series that aired on ABC from September 18, 1983, through May 5, 1986. The series stars Brian Keith as Judge Milton C. Hardcastle and Daniel Hugh Kelly as ex-con and race car driver Mark "Skid" McCormick.

During an interview in the early 1980s, producer Stephen J. Cannell referred to the then-upcoming series as Rolling Thunder.

By September 1985, domestic distribution rights to the series were sold to Columbia Pictures Television. Its successor, Sony Pictures Television, still holds these rights to this day.
Indian Institute of Science
The Indian Institute of Science (IISc) is a public, deemed, research university for higher education and research in science, engineering, design, and management. It is located in Bengaluru, Karnataka. The institute was established in 1909 with active support from Jamsetji Tata and thus is also locally known as the Tata Institute. It was granted a deemed university status in 1958 and recognized as an Institute of Eminence in 2018.

Fellow of the Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural knowledge, including mathematics, engineering science, and medical science".
Battle of Methven
The Battle of Methven took place at Methven, Scotland on 19 June 1306, during the Wars of Scottish Independence. The battlefield was researched to be included in the Inventory of Historic Battlefields in Scotland and protected by Historic Scotland under the Scottish Historical Environment Policy of 2009, but was excluded due to the uncertainty of its location.

John Comyn III of Badenoch
John Comyn III of Badenoch, nicknamed the Red (c. 1274 – 10 February 1306), was a leading Scottish baron and magnate who played an important role in the First War of Scottish Independence. He served as Guardian of Scotland after the forced abdication of his uncle, King John Balliol (r. 1292–1296), in 1296, and for a time commanded the defence of Scotland against English attacks. Comyn was stabbed to death by Robert the Bruce before the altar at the church of the Greyfriars at Dumfries.

His father, John Comyn II, known as the Black Comyn, had been one of the competitors for the Crown of Scotland, claiming his descent from King Donald III. His mother was Eleanor Balliol, sister of King John Balliol. He had, moreover, links with the royal house of England: in the early 1290s, he married Joan de Valence, cousin of King Edward I.
2nd Belorussian Front
The 2nd Belorussian Front (Russian: Второй Белорусский фронт, Vtoroi Belorusskiy Front, also romanized "Byelorussian"), was a major formation of the Soviet Army during World War II, being equivalent to a Western army group.

It was created in February 1944 as the Soviets were pushing the Germans back towards Byelorussia. General Colonel Pavel Kurochkin was its first commander. On hiatus in April 1944, its headquarters were reformed from the army headquarters of the disbanding 10th Army. They took part in the capture of Berlin, the capital of Nazi Germany.

Army Group Vistula
Army Group Vistula (German: Heeresgruppe Weichsel) was an Army Group of the Wehrmacht, formed on 24 January 1945. It lasted for 105 days, having been put together from elements of Army Group A (shattered in the Soviet Vistula-Oder Offensive), Army Group Centre (similarly largely destroyed in the East Prussian Offensive), and a variety of new or ad hoc formations. It was formed to protect Berlin from the Soviet armies advancing from the Vistula River.
Courtyard
A courtyard or court is a circumscribed area, often surrounded by a building or complex, that is open to the sky.

Courtyards are common elements in both Western and Eastern building patterns and have been used by both ancient and contemporary architects as a typical and traditional building feature. Such spaces in inns and public buildings were often the primary meeting places for some purposes, leading to the other meanings of court. Both of the words court and yard derive from the same root, meaning an enclosed space. See yard and garden for the relation of this set of words. In universities courtyards are often known as quadrangles.

Motte-and-bailey castle
A motte-and-bailey castle is a European fortification with a wooden or stone keep situated on a raised area of ground called a motte, accompanied by a walled courtyard, or bailey, surrounded by a protective ditch and palisade. Relatively easy to build with unskilled labour, but still militarily formidable, these castles were built across northern Europe from the 10th century onwards, spreading from Normandy and Anjou in France, into the Holy Roman Empire, as well as the Low Countries it controlled, in the 11th century, when these castles were popularized in the area that became the Netherlands. The Normans introduced the design into England and Wales. Motte-and-bailey castles were adopted in Scotland, Ireland, and Denmark in the 12th and 13th centuries. By the end of the 13th century, the design was largely superseded by alternative forms of fortification, but the earthworks remain a prominent feature in many countries.
Afrikaans
Afrikaans is a West Germanic language spoken in South Africa, Namibia, and to a lesser extent Botswana, Zambia, Zimbabwe, and also Argentina, where a group in Sarmiento speaks a Patagonian dialect. It evolved from the Dutch vernacular of South Holland (Hollandic dialect) spoken by the predominantly Dutch settlers and enslaved population of the Dutch Cape Colony, where in the 17th and 18th centuries it gradually developed characteristics that distinguish it from Dutch.

Although Afrikaans has adopted words from other languages, including German, Malay, and Khoisan languages, an estimated 90 to 95% of its vocabulary is of Dutch origin. Differences between Afrikaans and Dutch often lie in the more analytic morphology and grammar of Afrikaans, and different spellings. There is a large degree of mutual intelligibility between the two languages, especially in written form.

Southern Suburbs, Cape Town
The Southern Suburbs are a group of predominantly affluent, 
Anglophone suburbs in Cape Town, Western Cape, South Africa. The region is home to mainly detached homes, and features tree-lined streets and numerous public parks.

This group of neighborhoods includes, among others, Observatory, Mowbray, Pinelands, Rosebank, Rondebosch, Rondebosch East, Newlands, Claremont, Lansdowne, Kenilworth, Bishopscourt, Constantia, Wynberg, Ottery, Plumstead, Diep River, Meadowridge, Bergvliet, Tokai, Grassy Park, and Zeekoevlei.
Colobinae
The Colobinae or leaf-eating monkeys are a subfamily of the Old World monkey family that includes 61 species in 11 genera, including the black-and-white colobus, the large-nosed proboscis monkey, and the gray langurs. Some classifications split the colobine monkeys into two tribes, while others split them into three groups. Both classifications put the three African genera Colobus, Piliocolobus, and Procolobus in one group; these genera are distinct in that they have stub thumbs, hence their family name, which comes from Ancient Greek κολοβός (kolobós), meaning "docked". The various Asian genera are placed into another one or two groups. Analysis of mtDNA confirms the Asian species form two distinct groups, one of langurs and the other of the "odd-nosed" species, but are inconsistent as to the relationships of the gray langurs; some studies suggest that the gray langurs are not closely related to either of these groups, while others place them firmly within the langur group.

Raffles' banded langur
The Raffles' banded langur (Presbytis femoralis), also known as the banded leaf monkey or banded surili, is a species of primate in the family Cercopithecidae. It is endemic to Singapore and southern peninsular Malaysia. The species underwent taxonomic revisions in 2019 and 2020, in which two former subspecies were elevated to separate species. As a result, the Raffles' banded langur meets the criteria for being listed as critically endangered by the IUCN. It is mainly threatened by habitat loss.
Soft rock
Soft rock (also known as light rock, mellow rock or adult-oriented rock) is a form of rock music that originated in the late 1960s in the United States and the United Kingdom which smoothed over the edges of singer-songwriter and pop rock, relying on simple, melodic songs with big, lush productions. Soft rock was prevalent on the radio throughout the 1970s and eventually metamorphosed into a form of the synthesized music of adult contemporary in the 1980s.

Folktronica
Folktronica is a genre of indie electronic music comprising various elements of folk music and electronica, often featuring uses of acoustic instruments—especially stringed instruments—deploying hip hop, electronic or dance rhythms, and incorporating delicate, textural sound design, although it varies based on influences and choice of sounds. The Ashgate Research Companion to Popular Musicology describes folktronica as "a catch-all [term] for all manner of artists who have combined mechanical dance beats with elements of acoustic rock or folk".
Baron
Baron is a rank of nobility or title of honour, often hereditary, in various European countries, either current or historical. The female equivalent is baroness. Typically, the title denotes an aristocrat who ranks higher than a lord or knight, but lower than a viscount or count.  Often, barons hold their fief – their lands and income – directly from the monarch. Barons are less often the vassals of other nobles.  In many kingdoms, they were entitled to wear a smaller form of a crown called a coronet.

The term originates from the Latin term barō, via Old French. The use of the title baron came to England via the Norman Conquest of 1066, then the Normans brought the title to Scotland and Southern Italy. It later spread to Scandinavian and Slavic lands.

Primogeniture
Primogeniture (/ˌpraɪməˈdʒɛnɪtʃər, -oʊ-/) is the right, by law or custom, of the firstborn legitimate child to inherit all or most of their parent's estate, as well as succeed their parent as the ruler of a state.

Primogeniture stands in contrast to shared inheritance among all or some children, any illegitimate child or any collateral relative. In most contexts, it means the inheritance of the firstborn son (agnatic primogeniture). It can also mean by the firstborn daughter (matrilineal primogeniture), or firstborn child (absolute primogeniture).

Research shows that authoritarian regimes that rely on primogeniture for succession were more stable than forms of authoritarian rule with alternative succession arrangements. Scholars have linked primogeniture to a decline in regicide, as clear rules of succession reduce the number of people who could (absent a coup d'état) replace a ruler, thus making it less desirable to cause the death of the monarch.