hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
SMAD3
Mothers against decapentaplegic homolog 3 also known as SMAD family member 3 or SMAD3 is a protein that in humans is encoded by the SMAD3 gene.

SMAD3 is a member of the SMAD family of proteins. It acts as a mediator of the signals initiated by the transforming growth factor beta (TGF-β) superfamily of cytokines, which regulate cell proliferation, differentiation and death. Based on its essential role in TGF beta signaling pathway, SMAD3 has been related with tumor growth in cancer development.

SMAD7
Mothers against decapentaplegic homolog 7 or SMAD7 is a protein that in humans is encoded by the SMAD7 gene.

SMAD7 is a protein that, as its name describes, is a homolog of the Drosophila gene: "Mothers against decapentaplegic". It belongs to the SMAD family of proteins, which belong to the  TGFβ superfamily of ligands. Like many other TGFβ family members, SMAD7 is involved in cell signalling. It is a TGFβ type 1 receptor antagonist. It blocks TGFβ1 and activin associating with the receptor, blocking access to SMAD2. It is an inhibitory SMAD (I-SMAD) and is enhanced by SMURF2.

Smad7 enhances muscle differentiation.
Associação Portuguesa de Desportos
Associação Portuguesa de Desportos, commonly referred to as Portuguesa or Lusa, is a Brazilian professional football club based in the district of Pari, São Paulo, that competes in the Campeonato Paulista, the top tier of the São Paulo state football league, and the Campeonato Brasileiro Série D. It is part of a sports club, founded on 14 August 1920, by the Portuguese population of the city.

Sociedade Esportiva e Recreativa Caxias do Sul
Sociedade Esportiva e Recreativa Caxias do Sul, commonly known as Caxias, is a Brazilian professional association football club based in Caxias do Sul, Rio Grande do Sul. The team plays in Série C, the third tier of the Brazilian football league system, as well as in the Gauchão Série A, the top tier of the Rio Grande do Sul state football league.

Caxias won the Campeonato Gaúcho – Rio Grande do Sul State Championship in 2000.

Its fiercest rival is Juventude, the other club based in Caxias do Sul. The local derby is known as Ca-Ju. As of 2024, the Grená is ranked as the 74th best team in Brazil, according to the Brazilian Football Confederation Ranking.
Mandya
Mandya (pronunciationⓘ) is a city in the state of Karnataka. It is the headquarters of Mandya district. It is also called Sugar City (Kannada: Sakkare Nagara) because sugarcane is a major crop grown here, and sugar factories contribute to the major economic output. The district offices are located here. The city has been divided into 35 wards of the Mandya City Municipal Council.

Tumkur
Tumkur, officially Tumakuru, is a city and the headquarters of Tumkur district in Karnataka state, India. It is known for the Siddaganga Matha Lingayat monastery. Tumkur hosts India's first mega food park, a project of the ministry of food processing. The India Food Park was inaugurated by Prime Minister of India in September 2014. It is also included in the Smart Cities Mission list and is among the 100 smart cities to be developed in India. Since 28 August 2010, Tumkur has been accorded the status of a city corporation.

Tumkur is an emerging industrial hub in India, and has a large upcoming industrial corridor as well as a Japanese township. A new International stadium is expected to be completed in Tumkur by 2028, where international cricket tournaments can be hosted. The Green Line of the Bengaluru Namma Metro extension is planned to connect with Tumkur after 2030.
Mattel
Mattel, Inc. (/məˈtɛl/ mə-TEL) is an American multinational toy manufacturing and entertainment company headquartered in El Segundo, California. Founded in Los Angeles by Harold Matson and Ruth and Elliot Handler in January 1945, Mattel has a presence in 35 countries and territories. Its products are sold in more than 150 countries.

Mattel is the world's second largest toy maker in terms of revenue, after the Lego Group. Two of Mattel's major brands, Barbie and Hot Wheels, were named the top global toy property and the top-selling global toy of the year for 2020 and 2021 by the NPD Group.

General Mills
General Mills, Inc., is an American multinational manufacturer and marketer of branded consumer foods sold through retail stores. Founded on the banks of the Mississippi River at Saint Anthony Falls in Minneapolis, the company originally gained fame for being a large flour miller. It is headquartered in Golden Valley, Minnesota, a suburb of Minneapolis.

Today, the company markets many well-known North American brands, including Gold Medal flour, Annie's Homegrown, Lärabar, Cascadian Farm, Betty Crocker, Nature Valley, Totino's, Pillsbury, Old El Paso, Häagen-Dazs, as well as breakfast cereals under the General Mills name, including Cheerios, Wheaties, Chex, Lucky Charms, Trix, Cocoa Puffs, and the monster cereals.
Roman Safiullin
Roman Rishatovich Safiullin (born 7 August 1997) is a Russian professional tennis player. He has a career-high ATP singles ranking of world No. 36, achieved on 8 January 2024 and a best doubles ranking of No. 151, achieved on 19 August 2024.

Lorenzo Musetti
Lorenzo Musetti (Italian pronunciation: [loˈrɛntso muˈzetti]; born 3 March 2002) is an Italian professional tennis player. He has been ranked by the Association of Tennis Professionals (ATP) as high as world No. 5 in singles and No. 85 in doubles, both achieved on 12 January 2026. Musetti has won two ATP Tour titles in singles and one in doubles. He has reached the quarterfinals at all four majors, and made two semifinal appearances at the 2024 Wimbledon Championships and 2025 French Open.

Representing his country, Musetti won the bronze medal in men's singles at the 2024 Olympic Games. He was part of the Italian team that won the Davis Cup in 2023 and 2024.
Orpington railway station
Orpington railway station is on the South Eastern Main Line, serving the town of Orpington in the London Borough of Bromley, south-east London. It is 13 miles 65 chains (22.2 km) down the line from London Charing Cross and is situated between Petts Wood and Chelsfield stations. It is in London fare zone 6.

Southeastern (train operating company)
SE Trains Limited, trading as Southeastern, is a state-owned British train operating company in the south east of England. It operates services to destinations in Kent, London and East Sussex, including the domestic services on High Speed 1.

It is owned by DfT Operator, which took over operating the South Eastern franchise from privately owned London & South Eastern Railway (which also traded as Southeastern) on 17 October 2021.
James McCulloch
Sir James McCulloch, KCMG (18 March 1819 – 31 January 1893) was a British colonial politician and statesman who served as the fifth premier of Victoria over four non-consecutive terms from 1863 to 1868, 1868 to 1869, 1870 to 1871 and 1875 to 1877. He is the third longest-serving premier in Victorian history.

John O'Shanassy
Sir John O'Shanassy, KCMG (18 February 1818 – 5 May 1883), was an Irish-Australian politician who served as the 2nd Premier of Victoria. O'Shanassy was born near Thurles in County Tipperary, Ireland, the son of a surveyor, and came to the Port Phillip District (later Victoria) in 1839. He went into business in Melbourne as a draper, and by 1846 he was rich enough to be elected to the Melbourne City Council and to become the founding chairman of the Colonial Bank of Australasia. By the 1850s he was a major landowner and one of the wealthiest men in the colony. He also became a recognised leader of the large Irish Catholic community.
Redfern, New South Wales
Redfern is an inner southern suburb of Sydney located 3 kilometres (1.9 mi) south of the Sydney central business district and is part of the local government area of the City of Sydney. Strawberry Hills is a locality on the border with Surry Hills. The area experienced the process of gentrification and is subject to extensive redevelopment plans by the state government, to increase the population and reduce the concentration of poverty in the suburb and neighbouring Waterloo (see Redfern-Eveleigh-Darlington).

Alexandria, New South Wales
Alexandria is an inner southern suburb of Sydney, New South Wales, Australia. Alexandria is located 5 kilometres south of the Sydney central business district and is part of the local government area of the City of Sydney. The postcode is 2015.

The rough boundaries of Alexandria are Botany Road to the east, Gardeners Road to the south, Mitchell Road and Sydney Park to the west, and Boundary Road to the north. It is approximately 3.5 km south of Central station.
Barge
A barge is typically a flat-bottomed boat which does not have its own means of mechanical propulsion. Their original use was on inland waterways, while modern use is on both inland and marine water environments. The first modern barges were pulled by tugs, but on inland waterways, most are pushed by pusher boats, or other vessels. The term barge has a rich history, and therefore there are many types of barges.

Landing craft
Landing craft are small and medium seagoing watercraft, such as boats and barges, used to convey a landing force (infantry and vehicles) from the sea to the shore during an amphibious assault. The term excludes landing ships, which are larger. Production of landing craft peaked during World War II, with a significant number of different designs produced in large quantities by the United Kingdom and United States.

Because of the need to run up onto a suitable beach, World War II landing craft were flat-bottomed, and many designs had a flat front, often with a lowerable ramp, rather than a normal bow. This made them difficult to control and very uncomfortable in rough seas. The control point (too rudimentary to call a bridge on LCA and similar craft) was normally at the extreme rear of the vessel, as were the engines. In all cases, they were known by an abbreviation derived from the official name rather than by the full title.
Warrington Wolves
The Warrington Wolves are a professional rugby league club based in Warrington, England. They play home games at the Halliwell Jones Stadium and compete in the Super League, the top tier of British rugby league. 
Warrington are the only British-based club to have played every season in the top flight. They have won the League Championship three times and the Challenge Cup nine times.

The club's traditional home colours are white, primrose and blue. Warrington have local rivalries with Widnes Vikings, St Helens, Wigan Warriors, Salford Red Devils and Leigh Leopards.

Rugby league county leagues
The Yorkshire League and the Lancashire League formed two sections of the Rugby Football League Championship for much of its history. Initially, the 22 clubs that broke away in 1895 played in one combined league; however, the following season saw the addition of many clubs, and the League was split into two separate county competitions.
Vifor-class destroyer
The Vifor class was a group of four destroyers ordered by Romania in 1913 and built in Italy during the First World War. The four ships were however requisitioned by Italy in 1915 and rearmed as scout cruisers (esploratori), subsequently seeing service in World War I. Two were re-purchased by Romania in 1920 and saw service in World War II. The other two were eventually transferred by Italy to the Spanish Nationalists and saw service during the Spanish Civil War.

Regele Ferdinand-class destroyer
The Regele Ferdinand class was a pair of destroyers built in Italy for the Romanian Navy during the late 1920s. The sister ships were the most modern and powerful warships of the Axis powers in the Black Sea during World War II. During the war they participated in the 1941 Raid on Constanța and the 1944 evacuation of the Crimea, although they spent the vast majority of the war escorting convoys in the Black Sea. The Romanians claimed that they sank two submarines during the war, but Soviet records do not confirm their claims. Following King Michael's Coup, where Romania switched sides and joined the Allies in late 1944, the two ships were seized and incorporated into the Soviet Black Sea Fleet. They were returned to Romania in 1951 and served until 1961 when they were scrapped.
Taunton (UK Parliament constituency)
Taunton  was a constituency represented in the House of Commons of the Parliament of the United Kingdom and its predecessors from 1295 to 2010, taking its name from the town of Taunton in Somerset. Until 1918, it was a parliamentary borough, electing two Member of Parliaments (MPs) between 1295 and 1885 and one from 1885 to 1918; the name was then transferred to a county constituency, electing one MP.

In the boundary changes that came into effect at the general election of 2010, the Boundary Commission for England replaced Taunton with a modified constituency called Taunton Deane, to reflect the district name.  The new constituency's boundaries are coterminous with the local government district of the same name.

Somerset (UK Parliament constituency)
Somerset was a parliamentary constituency in Somerset, which returned two Members of Parliament (MPs), known traditionally as knights of the shire, to the House of Commons of England until 1707, the House of Commons of Great Britain from 1707 to 1800, and the House of Commons of the United Kingdom from 1801 to 1832.

Elections were held by the bloc vote system.
Kyushu
Kyushu (九州, Kyūshū; pronounced [kʲɯꜜː.ɕɯː] ⓘ, lit. 'nine provinces') is the third-largest and most southerly of Japan's four main islands. In the past, it has been known as Kyūkoku (九国, "Nine Countries"), Chinzei (鎮西, "West of the Pacified Area") and Tsukushi-no-shima (筑紫島, "Island of Tsukushi"). The historical regional name Saikaidō (西海道; lit. West Sea Circuit) referred to Kyushu and its surrounding islands. Kyushu has a land area of 36,782 square kilometres (14,202 sq mi) and a population of 14,311,224 in 2018.

There is a theory that Kyushu was in ancient times home to its own independent dynasty, where a unique, southern-influenced culture and tradition distinct from that of Honshu flourished.

In the 8th-century Taihō Code reforms, Dazaifu was established as a special administrative term for the region.

United States Third Fleet
The United States Third Fleet is one of the numbered fleets in the United States Navy. Third Fleet's area of responsibility includes approximately fifty million square miles of the eastern and northern Pacific Ocean areas including the Bering Sea, Alaska, the Aleutian Islands, and a sector of the Arctic. Major oil and trade sea lines of communication within this area are critically important to the economic health of the United States and friendly nations throughout the Pacific Rim region.

First established in 1943, the Third Fleet conducted extensive operations against Japanese forces in the Central Pacific during World War II. Deactivated in 1945, the fleet remained inactive until 1973, when it was reactivated and assumed its current responsibilities.
Minister of State (Ireland)
A minister of state (Irish: Aire Stáit) in Ireland (often called a junior minister, aire sóisearach) is a minister of non-cabinet rank attached to one or more Departments of State of the Government of Ireland and assists the Minister of the Government responsible for that department. The government may appoint up to 23 ministers of state.

Seanad Éireann
53°20′26″N 6°15′14″W﻿ / ﻿53.34055°N 6.254021°W﻿ / 53.34055; -6.254021
Seanad Éireann (/ˈʃænəd ˈɛərən, ˈʃænəð/ ⓘ SHAN-əd(h) AIR-ən; Irish: [ˈʃan̪ˠəd̪ˠ ˈeːɾʲən̪ˠ]; "Senate of Ireland") is the upper house of the Oireachtas (the Irish legislature), which also comprises the President of Ireland and Dáil Éireann (the lower house).

It is commonly called the Seanad or Senate and its members are known as senators (Irish: seanadóirí, singular: seanadóir). Unlike Dáil Éireann, it is not directly elected but consists of a mixture of members chosen by various methods. Its powers are much weaker than those of the Dáil and it can only delay laws with which it disagrees, rather than veto them outright. It can introduce new legislation. Since its establishment, it has been located in Leinster House.
John Riggi
John Riggi is an American television writer, producer, director, and actor who has worked on various television shows.  He is from Cincinnati, Ohio.  He attended high school at Elder High School, in Cincinnati, OH, and graduated from the University of Cincinnati in 1978 with a degree in biology.

He has worked as a writer on the NBC comedy series 30 Rock. He was nominated for the Writers Guild of America Award for Best Comedy Series at the February 2009 ceremony for his work on the third season of 30 Rock.

Kay Cannon
Kay Cannon (born August 21, 1974) is an American screenwriter, producer, director, and actress. She is best known for writing and producing the Pitch Perfect film series (2012–2017). She made her directorial debut with the comedy film Blockers (2018). 
Cannon was also a writer and producer for the NBC comedy series 30 Rock (2007–2012) and the FOX comedy series New Girl (2012–2014). She created, wrote and produced the short-lived Netflix comedy-drama series Girlboss (2017).
I-house
The I-house is a vernacular house type, popular in the United States from the colonial period onward. The I-house was so named in the 1930s by Fred Kniffen, a cultural geographer at Louisiana State University who was a specialist in folk architecture. He identified and analyzed the type in his 1936 study of Louisiana house types.

He chose the name "I-house" because the style was commonly built in the rural farm areas of Indiana, Illinois and Iowa, all states beginning with the letter "I". But he was not implying that this house type originated in, or was restricted to, those three states. It is also referred to as Plantation Plain style.

Ell (architecture)
In architecture, an ell is a wing of a building perpendicular (at a right angle) to the length of the main portion (main range).

It takes its name from the shape of the letter L.  Ells are often additions to a building.  Unless sub-wings or a non-rectangular outline floor plan exists such a wing makes the building L-shaped or T-shaped "in plan" (shape from above/below), though if not central nor at one end of the building the T-shape will be an offset T.  Where a building is aligned closely to cardinal compass points, such a wing may be more informatively described by its related side of the building (such as "south wing of the building").
Lawrence Ho
Lawrence Ho Yau-lung (Chinese: 何猷龍; born 1977) is a Canadian businessman.  Starting his career as an investment banker at Jardine Fleming and Citibank, in 2001 he took over operations at Melco International. Later named chairman and CEO,  Ho refocused the company on leisure and entertainment,  building and operating casino resorts in Macau, the Philippines, and Cyprus. With an estimated net worth of $2.2 billion, he was named "Asia’s Best CEO" at the Asian Excellence Awards for the seventh time in 2018.

Born in Hong Kong from a Eurasian business family, Lawrence Ho was educated in Canada and graduated from the University of Toronto.

Daisy Ho
Daisy Ho Chiu-fung (Chinese: 何超鳳; born 1964) is a Hong Kong businesswoman who is the daughter of Macau-based businessman Stanley Ho. She is the chairman and executive director of SJM Holdings, a major owner, operator and developer of casinos in Macau. She is also an executive director of Shun Tak Holdings.
Tokugawa Yoshinobu
Prince Yoshinobu Tokugawa (德川 慶喜, Tokugawa Yoshinobu; 28 October 1837 – 22 November 1913) was a Japanese samurai, daimyo and the 15th and last shōgun of the Tokugawa shogunate of Japan. He was part of a movement which aimed to reform the aging shogunate, but was ultimately unsuccessful. He resigned his position as shogun in late 1867, while aiming at keeping some political influence. After these efforts failed following the defeat at the Battle of Toba–Fushimi in early 1868, he went into retirement, and largely avoided the public eye for the rest of his life.

Government of Meiji Japan
The Government of Meiji Japan (明治政府, Meiji seifu) was the government that was formed by politicians of the Satsuma Domain and Chōshū Domain in the 1860s. The Meiji government was the early government of the Empire of Japan.

Politicians of the Meiji government were known as the Meiji oligarchy, who overthrew the Tokugawa shogunate.
Eugene Lee (designer)
Eugene Edward Lee (March 9, 1939 – February 6, 2023) was an American set designer who worked in film, theater, and television. He was the production designer for Saturday Night Live  from the show's premiere in 1975 until his death, with the exception of seasons 6-10 (1980-1985). Lee became resident designer at Trinity Repertory Company in Providence, Rhode Island, in 1967.

Keith Raywood
Keith Ian Raywood is an American production designer best known as Art Director for Saturday Night Live (SNL) since 1985 and Production Designer for SNL since 1990. He has designed music videos and live performances for major recording artists, international and national commercial spots, MSG & MSG+ networks, and theatre productions both regional and in New York.
Degree of a field extension
In mathematics, more specifically field theory, the degree of a field extension is a rough measure of the "size" of the field extension. The concept plays an important role in many parts of mathematics, including algebra and number theory—indeed in any area where fields appear prominently.

Algebraic number field
In mathematics, an algebraic number field (or simply number field) is an extension field  of the field of rational numbers  such that the field extension  has finite degree (and hence is an algebraic field extension).
Thus  is a field that contains  and has finite dimension when considered as a vector space over .

The study of algebraic number fields, that is, of algebraic extensions of the field of rational numbers, is the central topic of algebraic number theory. This study reveals hidden structures behind the rational numbers, by using algebraic methods.
Ancient Diocese of Stavanger
The former Catholic Diocese of Stavanger in Norway included the modern counties of Rogaland and Agder together with the regions of Valdres and Hallingdal and the parishes of Eidfjord and Røldal from Hordaland. It existed from the beginning of the 12th century to the Protestant Reformation.

Catholic Diocese of Bergen
The Catholic Diocese of Bergen or Diocese of Bjørgvin in Norway existed from the eleventh century to the Protestant Reformation (1537), and included the (modern) Vestland county (with exception of the parishes Eidfjord and Røldal).

Originally (from 1068) the diocese served all the area of Gulating: the modern counties of Vestland, Rogaland, and Agder - and the regions of Sunnmøre, Valdres and Hallingdal.

When the Diocese of Stavanger was established, around 1125, the counties of Rogaland, Aust-Agder and Vest-Agder were transferred to the new diocese - together with the regions of Valdres and Hallingdal (and the parishes of Eidfjord and Røldal from Hordaland).

The region Sunnmøre was transferred to the Archdiocese of Nidaros some time after 1152 - to secure more income for the Archdiocese.
Nara Leão
Nara Lofego Leão (Portuguese pronunciation: [ˈnaɾɐ leˈɐ̃w, li-]; January 19, 1942 – June 7, 1989) was a Brazilian bossa nova and MPB (popular Brazilian music) singer and occasional actress. Leão was married twice, to Ruy Guerra and subsequently Carlos Diegues, both film directors.

Ronaldo Bôscoli
Ronaldo Fernando Esquerdo Bôscoli, usually known as Ronaldo Bôscoli, or just Bôscoli  (28 October 1928 – 18 November 1994) was a Brazilian composer, songwriter, record producer and journalist.

He was very active and significant in the creation and development of the Bossa nova style in Brazil.