hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Bleximenib
Bleximenib (INN: bleximenib; development code JNJ-75276617) is an orally available investigational new drug developed by Johnson & Johnson's Janssen Pharmaceuticals for the treatment of acute myeloid leukemia (AML). It belongs to a novel class of menin inhibitors that selectively disrupt the protein-protein interaction between menin and KMT2A (lysine methyltransferase 2A), representing a precision medicine strategy for patients with specific genetic alterations.

Bleximenib is designed for acute leukemias with KMT2A rearrangements or NPM1 mutations, alterations that together occur in about 40% of AML cases. The compound shows high potency with IC50 values in the nanomolar range and has demonstrated encouraging activity in early-phase clinical trials, both as monotherapy and in combination with standard-of-care treatments.

MEN1
Menin is a protein that in humans is encoded by the MEN1 gene. Menin is a putative tumor suppressor associated with multiple endocrine neoplasia type 1 (MEN-1 syndrome) and has autosomal dominant inheritance. Variations in the MEN1 gene can cause pituitary adenomas, hyperparathyroidism, pancreatic neuroendocrine tumors, gastrinoma, and adrenocortical cancers.

In vitro studies have shown that menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD.  However, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Two variants of the shorter transcript have been identified where alternative splicing affects the coding sequence. Five variants where alternative splicing takes place in the 5' UTR have also been identified.
Cloyne
Cloyne (Irish: Cluain) is a small town located to the southeast of Midleton in eastern County Cork, Ireland. It is also a see city of the Anglican (Church of Ireland) Diocese of Cork, Cloyne and Ross, while also giving its name to a Roman Catholic diocese. The town is in a civil parish of the same name. St Colman's Cathedral in Cloyne is a cathedral church of the Church of Ireland while the Pro Cathedral of the Roman Catholic Diocese of Cloyne, Cobh Cathedral of Saint Colman, overlooks Cork Harbour. Cloyne is within the Cork East Dáil constituency.

Cork East (Dáil constituency)
Cork East is a parliamentary constituency in County Cork represented in Dáil Éireann, the lower house of the Irish parliament or Oireachtas. The constituency elects four deputies (Teachtaí Dála, commonly known as TDs) on the system of proportional representation by means of the single transferable vote (PR-STV).
Ray Culley
Raymond Francis Culley (October 12, 1904 - September 18, 1983) and his wife, Betty (Buehner) Culley  (May 16, 1914 – June 4, 2016), co-founded Cinécraft Productions, Inc., a sponsored film studio, in 1939. Promoting "Sound Business Pictures in Natural Color," Cinécraft specialized in producing films and slide shows for businesses.

The Culleys were early users of multiple-camera setups with teleprompters to film the same scene from different angles simultaneously. They called their technique Cinéscope.

Ray Culley directed the first half-hour TV infomercial. The infomercial featured William Grover “Papa” Barnard selling Vitamix blenders on a show called “Home Miracles of the 1950s.”

Ray Culley also directed early TV sewing, cooking, and craft films featuring  Louise Winslow, the "Martha Stewart of early daytime television."

Vitamix
Vita-Mix Corporation, doing business as Vitamix, is an American company that manufactures and sells commercial and residential blenders. Vitamix was founded in 1921 by William Grover Barnard and is privately owned by the Barnard family. It has been based in Olmsted Township, Ohio, since 1948. It employs more than 700 people, most at its Northeast Ohio headquarters and manufacturing facilities. Vitamix products are sold in over 130 countries.
HMS Stonehenge
Two vessels of the Royal Navy have been named HMS Stonehenge after the prehistoric monument of Stonehenge.

HMS Stonehenge (1919) was an S-class destroyer, built in 1919 and wrecked in 1920 near Smyrna.

HMS Stonehenge (P232) was an S-class submarine, built in 1943 and lost in 1944 in the Malacca Straits.

S-class destroyer (1917)
The S class (initially known as the Modified Trenchant class) was a class of 67 destroyers ordered for the Royal Navy in 1917 under the 11th and 12th Emergency War Programmes. They saw active service in the last months of the First World War and in the Russian and Irish Civil Wars during the early 1920s.  Most were relegated to the reserve by the mid-1920s and subsequently scrapped under the terms of the London Naval Treaty. Eleven survivors saw much action during the Second World War.
Karunaratne Abeysekera
Karunaratne Abeysekera (3 June 1930 – 20 April 1983) was one of Sri Lanka's most famous Sinhala broadcasters. He was also a poet and songwriter and was widely admired for his excellent command of Sinhala.

Abeysekera wrote the lyrics to over 2,000 songs, a record for a lyricist in Sri Lanka. His compositions are still covered by some of the island's top musicians to this day, introducing his lyrics to new audiences in South Asia, and his songs are played regularly by the Sri Lanka Broadcasting Corporation.

Lyricist
A lyricist is a writer who writes lyrics (the spoken words), as opposed to a composer, who writes the song's music which may include (but is not limited to) the melody, harmony, arrangement and accompaniment.
Panic in Chicago
Panic in Chicago (German: Panik in Chicago) is a 1931 German crime film directed by Robert Wiene and starring Olga Chekhova, Hans Rehmann and Ferdinand Hart. It was based on the novel Panic in Chicago by the German writer Robert Heymann. The film was shot at the Staaken Studios with sets designed by the art director Erwin Scharf. It premiered at the Palast-am-Zoo in Berlin on 23 June 1931.

Robert Wiene
Robert Wiene (German: [ˈviːnə]; 27 April 1873 – 17 July 1938) was a German film director, screenwriter and producer, active during the silent era. He is widely-known for directing the landmark 1920 film The Cabinet of Dr. Caligari and a succession of other expressionist films. Wiene also directed a variety of other films of varying styles and genres. Following the Nazi rise to power in Germany, Wiene, who was of Jewish descent, fled into exile.
Michael Schrodi
Michael Schrodi (born 3 July 1977) is a German teacher and politician of the Social Democratic Party (SPD) who has been serving as a member of the Bundestag from the state of Bavaria since 2017.

In addition to his parliamentary work, Schrodi has been serving as a Parliamentary State Secretary at the Federal Ministry of Finance in the government of Chancellor Friedrich Merz since 2025.

Merz cabinet
The Merz cabinet (German: Kabinett Merz, pronounced [kabiˈnɛt ˈmɛʁts]) is the 25th and current Government of the Federal Republic of Germany during the 21st legislative session of the Bundestag. It succeeded the previous cabinet led by Olaf Scholz. The cabinet is led by Friedrich Merz.

The cabinet is composed of Merz's Christian Democratic Union (CDU), its Bavarian sister-party Christian Social Union (CSU) (which form the CDU/CSU alliance; the so called Union) and the Social Democratic Party (SPD). It is the fifth time a governing coalition between Union and SPD has been formed in post-war German history and the first since the Fourth Merkel cabinet led by then-Chancellor Angela Merkel in 2018.
IROKO Partners
iROKO Partners is an online media distribution company focused on the Nigerian entertainment industry. The company was established in September 2010 and is headquartered in Lagos, with a branch in London, United Kingdom. The company is led by its co-founders Jason Njoku (CEO) and Bastian Gotter along with major investor Nazar Yasin.  iROKO Partners offers a range of online media products including its movie streaming website named IROKOtv focused on Nollywood Film productions, and 'iROKING', a Nigerian music streaming platform. Other web brands are NollywoodLove and YorubaLove which operate on the YouTube video platform.

International Media Distribution
International Media Distribution (IMD) (formerly International Networks), a division of NBCUniversal, is an American provider of in-language networks which facilitates the distribution of Asian, European, Middle Eastern and Hispanic channels and Video On Demand services across all platforms including, cable, satellite and OTT.
Communist Party of Germany (1990)
The Communist Party of Germany (German: Kommunistische Partei Deutschlands, abbreviated as KPD) is a Marxist-Leninist communist party in Germany. It is one of several parties which claim the KPD name and/or legacy. It was founded in Berlin in 1990. The party is also commonly referred to by the name KPD-Ost (English: KPD-East) to differentiate it from other parties with the same name, most prominently the historical Communist Party of Germany.

Zeitz
Zeitz (German pronunciation: [ˈtsaɪts] ⓘ; Upper Sorbian: Žič, pronounced [ˈʒitʃ]) is a town in the Burgenlandkreis district, in Saxony-Anhalt, Germany. It is situated on the river White Elster, in the triangle of the federal states Saxony-Anhalt, Thuringia, and Saxony.
Quest of the Great Jewels
Quest of the Great Jewels is a closed-end, computer moderated, play-by-email game. It was initially published and moderated by Zorph Enterprises in the early 1980s. The game was created by Mike Shefler.

Dragon (magazine)
Dragon was one of the two official magazines for source material for the Dungeons & Dragons role-playing game and associated products, along with Dungeon.

TSR, Inc. originally launched the monthly printed magazine in 1976 to succeed the company's earlier publication, The Strategic Review.  The final printed issue was #359 in September 2007. Shortly after the last print issue shipped in mid-August 2007, Wizards of the Coast (part of Hasbro, Inc.), the publication's current copyright holder, relaunched Dragon as an online magazine, continuing on the numbering of the print edition. The last published issue was No. 430 in December 2013. A digital publication called Dragon+, which replaced Dragon magazine, was launched in 2015. It was created by the advertising agency Dialect in collaboration with Wizards of the Coast, and its numbering system for issues started at No. 1.
2015 Japan Series
The 2015 Japan Series was the 66th edition of Nippon Professional Baseball's postseason championship series. The Fukuoka SoftBank Hawks, champions of the Pacific League, played the Tokyo Yakult Swallows, champions of the Central League. The Hawks were the defending Japan Series champions, having beaten the Hanshin Tigers in 2014. The series was sponsored by the Sumitomo Mitsui Banking Corporation (SMBC) and was officially known as the SMBC Nippon Series 2015.

The Hawks defeated the Swallows in five games. Lee Dae-ho won the Japan Series Most Valuable Player Award. Kenji Akashi, Shota Takeda, and Rick van den Hurk (all of the Hawks) won outstanding player awards, while Tetsuto Yamada of the Swallows won the Fighting Spirit Award.

Sumitomo Mitsui Banking Corporation
Sumitomo Mitsui Banking Corporation (株式会社三井住友銀行, Kabushiki-gaisha Mitsui Sumitomo Ginkō; SMBC) is a Japanese multinational banking financial services institution owned by the Sumitomo Mitsui Financial Group, which is also known as the SMBC Group. It is headquartered in the same building as SMBC Group in Marunouchi, Chiyoda, Tokyo, Japan.

SMBC was established in 2001 through the merger of the Sakura Bank, which originated from the Mitsui zaibatsu and was founded as Mitsui Bank in 1876, and The Sumitomo Bank, which originated from the Sumitomo zaibatsu and was founded in 1895.
Harry E. Trout
Harry Edgar Trout (April 4, 1876 – January 11, 1941) was an American college football coach. He serve as the ninth head football coach at West Virginia University in Morgantown, West Virginia and he held that position for the 1903 season. His coaching record at West Virginia was 7–1.

Trout was the first coach at West Virginia to record a victory over rival Washington and Jefferson with a 6–0 win on November 26, 1903. The game marked not only the first victory over Washington and Jefferson, but the first time after nine attempts West Virginia had managed to score against the "Presidents".

Trout graduated from Lafayette College in 1903 and married Jane McBride of Portland, Oregon in January 1913 at Chicago. Trout later worked for a steel company in Pennsylvania. From 1936 to 1938 he served on the Lafayette College board of trustees. He died January 11, 1941, in Johnstown and was buried in Granview Cemetery in that city.

Lafayette College
Lafayette College is a private liberal arts college in Easton, Pennsylvania, United States. Founded in 1826 by James Madison Porter and other citizens in Easton, the college first held classes in 1832. The founders voted to name the college after the Marquis de Lafayette, a hero of the American Revolution.

Located on College Hill in Easton, the campus overlooks the Delaware River and is situated in the Lehigh Valley, about 70 mi (110 km) west of New York City and 60 mi (97 km) north of Philadelphia. Lafayette enrolls approximately 2,700 undergraduate students and offers programs in the humanities, social sciences, natural sciences, and engineering. The college emphasizes small class sizes and undergraduate research, and it competes in NCAA Division I athletics as a member of the Patriot League. As of 2024, its endowment was valued at over $1 billion.
Brovst Speedway Club
Brovst Speedway Club also known as Nordjysk Elite Speedway is a motorcycle speedway club from Brovst in Denmark, who competed in the Danish Speedway League until 2010, and then again in 2021. They are three times champions of Denmark, having won the title in 1990, 1998 and 2000.

Danish Speedway League
The Danish Speedway League (Danish: Dansk Speedway Liga) or Danish Super League or Metal League as it is called today is the top division of motorcycle speedway in Denmark.

In 1955, the idea of a Danish Tournament for teams surfaced. The Danish Speedway League began in 1956 for Frederiksborg (Hillerød), Amager, Odense and Randers.
2016 Laguna local elections
Local elections were held in Laguna on May 9, 2016, as part of the 2016 general election. Voters will select candidates for all local positions: a town mayor, vice mayor and town councilors, as well as members of the Sangguniang Panlalawigan, the vice-governor, governor and representatives for the four districts of Laguna, including the newly created Biñan lone district.

Incumbent Governor Ramil Hernandez is running for his first full three-year term as governor. Hernandez assumed the governorship in 2014 after the Commission on Elections disqualifies ER Ejercito for campaign overspending in the 2013 elections. Ejercito is seeking to regain his post.

Hernandez's running mate is Vice Governor Katherine Agapay while Niño Lajara is Ejercito's running mate.

San Pedro, Laguna
San Pedro, officially the City of San Pedro (Filipino: Lungsod ng San Pedro), is a  component city in the province of Laguna, Philippines. According to the 2024 census, it has a population of 348,968 people.

It is named after its patron saint, Saint Peter.

San Pedro has been dubbed as “dormitory town” of Metro Manila and migrants from other provinces commuting everyday through its highly efficient road and transport system. Despite being one of the smallest political units in the entire province, with a total land area of only 24.05 square kilometers (9.29 sq mi), San Pedro is the 5th most populous city (out of 6) after the cities of Biñan, Calamba, Santa Rosa and Cabuyao. The city also has the highest population density in the province of Laguna and in the whole Calabarzon region, having 15,000 inhabitants per square kilometer (39,000/sq mi). San Pedro became a component city of Laguna by virtue of Republic Act No. 10420 dated March 27, 2013.
The Deluge (painting)
The Deluge is an oil on canvas biblical landscape painting by the British artist J. M. W. Turner, from 1805. It features a vision of the biblical flood focused on a shipwreck.

It was first planned in 1804 and was originally a commission that fell through. The painting was likely to have been first exhibited at Turner's studio in Queen Anne Street in London in 1805. It was later submitted to the Royal Academy's Summer Exhibition of 1813 at Somerset House. Part of the Turner Bequest of 1856, it is now in the collection of the Tate Britain, in Pimlico.

Marylebone
Marylebone (usually /ˈmɑːrlɪbən/ MAR-lib-ən, also /ˈmærɪ(lə)bən/ MARR-il-ə-bən, MARR-ib-ən) is an area in London, England, and is located in the City of Westminster. It is in Central London and part of the West End. Oxford Street forms its southern boundary.

An ancient parish and latterly a metropolitan borough, it merged with the boroughs of Westminster and Paddington to form the new City of Westminster in 1965.

Marylebone station lies two miles north-west of Charing Cross.

The area is also served by numerous tube stations: Baker Street, Bond Street, Edgware Road (Bakerloo line), Edgware Road (Circle, District and Hammersmith & City lines), Great Portland Street, Marble Arch, Marylebone, Oxford Circus, and Regent's Park.
Ray Gibbon Drive
Ray Gibbon Drive, referred to as the West Regional Road during proposal and planning stages, is a major arterial road in St. Albert, Alberta. With the exception of the Edmonton portion of 184 Street, it is only partially constructed as a two-lane road. Currently, it is 8.2 kilometres (5.1 mi) long and runs between Anthony Henday Drive and Villeneuve Road. It was named at the official opening of Stage One in October 2007, after former mayor of St. Albert Ray Gibbon, who served from 1968 to 1974 and again in 1989. Gibbon died in 1999, but his wife and family were present for the official opening, riding in the vintage lead vehicle for the first use of the road.

Ray Gibbon Drive preceded in Edmonton as 184 Street, an arterial road which begins at 100 Avenue and travels north to Anthony Henday Drive.

St. Albert, Alberta
St. Albert is a suburban city in Alberta, Canada, next to the Sturgeon River, northwest of the City of Edmonton, the provincial capital. It was originally settled as a Métis community, and is now the second-largest city in the Edmonton Metropolitan Region. St. Albert first received its town status in 1904 and was reached by the Canadian Northern Railway in 1906. Originally separated from Edmonton by several miles of farmland, the 1980s expansion of Edmonton's city limits placed St. Albert immediately adjacent to the larger city on St. Albert's southern and eastern sides.
Philippine mythology
Philippine mythology is rooted in the many indigenous Philippine folk religions. Philippine mythology exhibits influence from Hindu, Muslim, Buddhist, and Christian traditions.

Philippine mythology includes concepts akin to those in other belief systems, such as the notions of heaven (kaluwalhatian, kalangitan, kamurawayan), hell (kasamaan, sulad), and the human soul (kaluluwa, kaulolan, makatu, ginoand kud,...).

The primary use of Philippine mythology is to explain the nature of the world, human existence, and life's mysteries. Myths include narratives of heroes, deities (anito, Diwata), and mythological creatures. These myths were transmitted through oral tradition, handed down through generations guided by spiritual leaders or shamans, (babaylan, katalonan, mumbaki, baglan, machanitu, walian, mangubat, bahasa,...), and community elders.

Tagalog religion
Tagalog religion mainly consists of Tagalog Austronesian religious elements, supplemented with other elements later obtained from Hinduism, Mahayana Buddhism, and Islam. It was contemporaneously referred to by Spanish priests as tagalismo (i.e., "Tagalism").

Many Tagalog religious rites and beliefs persist today as Tagalog Philippine syncretisms on Christianity and Islam. Tagalog religion was well documented by Spanish Catholic missionaries, mostly in epistolary accounts (relaciones) and entries in various dictionaries compiled by missionary priests.
Lindsay Robb
Lindsay Robb (1967–31 December 2005) was a Northern Irish loyalist who was a member of the Ulster Volunteer Force (UVF) before defecting to the Loyalist Volunteer Force (LVF). A native of Lurgan, County Armagh, Robb was a leading member of the Progressive Unionist Party (PUP) until 1995 when he was convicted of smuggling guns. Having been the main witness in the trial of a leading Provisional Irish Republican Army member in the early 1990s, Robb subsequently made a number of allegations about collusion between the British security forces and the loyalist paramilitaries. He later died in violent circumstances.

Progressive Unionist Party
The Progressive Unionist Party (PUP) is a minor unionist political party in Northern Ireland. It was formed from the Independent Unionist Group operating in the Shankill area of Belfast, becoming the PUP in 1979. Linked to the Ulster Volunteer Force (UVF) and Red Hand Commando (RHC), for a time it described itself as "the only left of centre unionist party" in Northern Ireland, with its main support base in the loyalist working class communities of Belfast.

Since the Ulster Democratic Party's dissolution in 2001, the PUP has been the sole party in Northern Ireland representing paramilitary loyalism.

The PUP has one elected representative on the Causeway Coast and Glens Borough Council, Russell Watton, the party's current leader.
1956 French legislative election in Upper Volta
Elections to the French National Assembly were held in Upper Volta on 2 January 1956 as part of the wider French elections. The results saw Gérard Kango Ouédraogo (Progressive Voltaic), Nazi Boni (African Popular Movement), Joseph Conombo and Henri Guissou (Social Party for the Emancipation of the African Masses) elected.

Gérard Kango Ouédraogo
Gérard Kango Ouédraogo  (French pronunciation: [ʒeʁaʁ kɑ̃ɡo wedʁaɔɡo]; September 19, 1925 – July 1, 2014) was a Burkinabé statesman and diplomat who served as Prime Minister of Upper Volta (now Burkina Faso) from 13 February 1971 to 8 February 1974. He was subsequently President of the National Assembly of Upper Volta from October 1978 to November 25, 1980.
Ekelund
Ekelund is a surname of Scandinavian origin. Notable people with the surname include:

Allan Ekelund (1918–2009), Swedish film producer

Bo Ekelund (1894–1983), Swedish Olympic athlete in the high jump

Henrik Ekelund, Swedish business consultant and executive

Hilding Ekelund (1893–1984), Finnish architect

Irene Ekelund (born 1997), Swedish athlete

Kalle Ekelund (born 1990), Swedish ice hockey player

Karin Ekelund (1913–1976), Swedish actress

Ole Magnus Ekelund (born 1980), Norwegian handball player

Robert Ekelund (born 1940), American economist

Ronnie Ekelund (born 1972), Danish football player

Vilhelm Ekelund (1880–1949), Swedish poet

Hilding Ekelund
Georg Hilding Ekelund (18 November 1893 in Kangasniemi – 30 January 1984 in Helsinki) was a Finnish architect, from 1950 to 1958 a professor of housing design at Helsinki University of Technology and from 1931 to 1934 editor-in-chief of the Finnish architects' journal Arkkitehti (Finnish Architectural Review). His career as an architect spans the change in styles in Finland from the Nordic Classicism of the 1920s to the Modernism of the 1970s.