hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Drug development
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug. The entire process—from concept through preclinical testing in the laboratory to clinical trial development, including Phase I–III trials—to approved vaccine or drug typically takes more than a decade.

Regulation
Regulation is the management of complex systems according to a set of rules and trends. In systems theory, these types of rules exist in various fields of biology and society, but the term has slightly different meanings according to context. For example:

in government, typically regulation (or its plural) refers to the delegated legislation which is adopted to enforce primary legislation; including land-use regulation

in economy: regulatory economics

in finance: financial regulation

in business, industry self-regulation occurs through self-regulatory organizations and trade associations which allow industries to set and enforce rules with less government involvement; and,

in biology, gene regulation and metabolic regulation allow living organisms to adapt to their environment and maintain homeostasis;

in psychology, self-regulation theory is the study of how individuals regulate their thoughts and behaviors to reach goals.
Buena Vista Beavers football
The Buena Vista Beavers football team represents Buena Vista University in college football at the NCAA Division III level. The Beavers are members of the American Rivers Conference (ARC), fielding its team in the A-R-C since 1923 when the conference was branded as the Iowa Intercollegiate Athletic Conference (IIAC). The Beavers play their home games at J. Leslie Rollins Stadium in Storm Lake, Iowa.

The team's head coach is Austin Dickinson, who took over the position for the 2023 season.

Buena Vista University
Buena Vista University is a private university in Storm Lake, Iowa, United States. Founded in 1891 as Buena Vista College, it is affiliated with the Presbyterian Church. The university's 60-acre (240,000 m2) campus is situated on the shores of Storm Lake, a 3,200-acre (13 km2) natural lake.

Buena Vista University offers 42 undergraduate majors at its Storm Lake campus. Seventeen additional locations throughout Iowa and online serve working adult and graduate students.
Telecommunications in the Federated States of Micronesia
This article is about communications systems in the Federated States of Micronesia.

In 2010, Pohnpei State was connected to the Internet using the HANTRU-1 undersea communications cable to provide high-speed bandwidth. Kosrae State, Chuuk State, and Yap State, were planned to be connected in a second phase.

HANTRU-1
HANTRU-1 is a submarine communications cable system that connects the Ronald Reagan Ballistic Missile Defense Test Site in the Kwajalein atoll to Guam. The cable was funded by $100 million from the US Army. Marshall Islands and Federated States of Micronesia arranged to add extensions to this trunk line for total of $30 million. It has cable landing points at:

Guam

Pohnpei, Federated States of Micronesia

Reagan Test Site, Kwajalein Atoll

Ebeye Island, Kwajalein Atoll

Majuro, Marshall Islands

HANTRU-1 is named after owner Hannon Armstrong Capital LLC and operator Truestone LLC. The dedicated Micronesian fiber pair will have an ultimate capacity to transmit 16 10-Gigabit wavelengths. The HANTRU-1 extensions were completed in March 2010. Previously connectivity to these island nations was only available using satellite transmission.
Alpena School District
Alpena School District is a public school district whose facilities are in Boone County, Arkansas, United States which serves most of the city of Alpena along with surrounding unincorporated areas within Boone, Carroll, and Newton counties.

Newton County, Arkansas
Newton County is a county in the U.S. state of Arkansas. As of the 2020 census, the population was 7,225. The county seat is Jasper.  Newton County is Arkansas's 46th county, formed on December 14, 1842, and named for Thomas W. Newton, an Arkansas Congressman.

Newton County is part of the Harrison, AR Micropolitan Statistical Area.

It is an alcohol prohibition or dry county.
STV Rugby
STV Rugby was a Scottish regional television programme featuring highlights of Pro12 rugby union matches involving Edinburgh Rugby and Glasgow Warriors. The programme, produced by the STV News department in Glasgow, was first broadcast in the 2009-10 season after a deal with the Celtic League Association, Scottish Rugby and STV was reached, following the closure of Setanta Sports in the UK.

Magners League rugby returned to STV for the 2010-11 season, under the new name of Sports Centre: Rugby. The STV Rugby brand returned for the 2011-12 season, after Sports Centre was axed. The 2012/2013 season was the last to be covered by STV Rugby.

Setanta Sports
Setanta Sports Media is a sports television company based in Dublin, Ireland and in Tbilisi, Georgia, the latter of which is managed by Adjarasport. Formed in 1990 to facilitate the broadcasting of Irish sporting events internationally, it operates channels in Eastern Europe and the Philippines and formerly Ireland (where it originated from), the UK, Asia, Africa, Australia, the United States and Canada.
Biliverdin reductase
Biliverdin reductase (BVR) is an enzyme (EC 1.3.1.24) found in all tissues under normal conditions, but especially in reticulo-macrophages of the liver and spleen.  BVR facilitates the conversion of biliverdin to bilirubin via the reduction of a double bond between the second and third pyrrole ring into a single bond.

There are two isozymes in humans, each encoded by its own gene, biliverdin reductase A (BLVRA) and biliverdin reductase B (BLVRB).

Pyrrole
Pyrrole is a heterocyclic, aromatic, organic compound, a five-membered ring with the formula C4H4NH. It is a colorless volatile liquid that darkens readily upon exposure to air. Substituted derivatives are also called pyrroles, e.g., N-methylpyrrole, C4H4NCH3. Porphobilinogen, a trisubstituted pyrrole, is the biosynthetic precursor to many natural products such as heme.

Pyrroles are components of more complex macrocycles, including the porphyrinogens and products derived therefrom, including porphyrins of heme, the chlorins, bacteriochlorins, and chlorophylls.
Bronze Medallion (Canada)
The Bronze Medallion is the second step towards the lifeguarding certification in Canada. The award is part of the Lifesaving Society's Bronze series of awards. It teaches an understanding of the lifesaving principles embodied in the four components of water rescue education: judgment, knowledge, skill, and fitness. It is the prerequisite for Bronze Cross, which along with Standard First Aid with CPR-C and 15 years of age are the prerequisites for National Lifeguard. The Bronze Medallion endurance swim requirement is 400 meters (440 yd) in 12 minutes using any combination of strokes.

Royal Life Saving Society Canada
The Royal Life Saving Society Canada, commonly known as the Lifesaving Society or LSS, is a Canadian registered charity that works to prevent water-related injuries through various programs across Canada. The Lifesaving Society is an independent organization that is composed of ten provincial/territorial branches, tens of thousands of individual members, and over 4,000 affiliated swimming pools, waterfronts, schools and clubs. The Society helps prevent drowning and aquatic injury through its training programs, public education, drowning-prevention research, safety management and overseeing the sport of lifesaving. They are one of five nationally recognized first aid training organizations in Canada, alongside the Heart and Stroke Foundation, Red Cross, St. John Ambulance, and the Canadian Ski Patrol.
Yazz Ahmed
Yazz Ahmed aka Yasmeen Ahmed (born 1983) is a British-Bahraini trumpeter, flugelhornist and composer. Her music mixes Arabic and Western influences.

She has worked with Toshiko Akiyoshi, Arturo O’Farrill, Ash Walker, the London Jazz Orchestra, and also recorded and performed with Radiohead, Lee Perry, ABC, Swing Out Sister, Joan as Police Woman, Tarek Yamani and Amel Zen, and the band These New Puritans.

These New Puritans
These New Puritans are an English band from Southend-on-Sea, England. It consists mainly of Jack Barnett (principal songwriter, vocalist, producer, multi-instrumentalist) and his twin brother George Barnett (drums, electronics, producer, artwork). Multi-instrumentalist Thomas Hein was an active member of TNP between 2006 and 2016; keyboardist Sophie Sleigh-Johnson was active between 2006 and 2010. Portuguese fado and jazz singer Elisa Rodrigues joined as a vocalist between 2012 and 2015. They have recorded five studio albums: Beat Pyramid (2008), Hidden (2010), Field of Reeds (2013), Inside the Rose (2019) and Crooked Wing (2025).

The band's music has been described as "blurring the distinction between rock, classical, electronic and experimental" and as "strikingly modern yet simultaneously timeless."
Rochelle Chronister
Rochelle Ruth Chronister (née Beach; August 27, 1939 – April 2, 2023) was an American politician from southwest Kansas who served in the Kansas Legislature, as the 57th Chairwoman of the Kansas Republican Party and as Secretary of the Kansas Department of Social and Rehabilitation Services.

Kansas Republican Party
The Kansas Republican Party is the state affiliate political party in Kansas of the United States Republican Party. The Kansas Republican Party was organized in May 1859.

At the state level, the party is largely split between its moderate and conservative ideological factions, with the moderates often willing to work with Democrats on legislation and other matters. Because of this divide, Kansas is sometimes described as having "three-party politics." In recent years, as the national Republican Party has grown more conservative, some moderates have left the party to become Democrats. It is currently the dominant party in the state, controlling all but one of Kansas' four U.S. House seats, both U.S. Senate seats, and supermajorities in both houses of the state legislature. The statewide offices that the party does not control are the governorship and the lieutenant governorship which are currently held by Democrats Laura Kelly and David Toland respectively.
Bras de la Rivière Saint-Denis
The Bras de la Rivière Saint-Denis is a tributary of the east bank of the Saint-Denis River which empties on the southeast bank of the Kamouraska River, which empties on the south shore of the St. Lawrence River two km east of the center of the village of Kamouraska.

The Bras de la Rivière Saint-Denis flows on the Côte-du-Sud in the municipalities of Mont-Carmel and Saint-Gabriel-Lalemant, in the Kamouraska Regional County Municipality, in the administrative region of Bas-Saint-Laurent, in province of Quebec, in Canada.

Kamouraska Regional County Municipality
Kamouraska (French pronunciation: [kamuʁaska] ⓘ) is a regional county municipality in eastern Quebec, Canada. The regional county municipality seat is Saint-Pascal, but the largest town is La Pocatière.

The area is an important research, development and education centre for agriculture. Factories in the region produce metal products and public transportation equipment. One of the people instrumental in settling and developing this area was Pascal Taché, an early seigneur.

The name "Kamouraska" comes from an Algonquin word meaning "where rushes grow at the water's edge".
Renshaw cell
Renshaw cells are inhibitory interneurons found in the gray matter of the spinal cord, and are associated in two ways with an alpha motor neuron.

They receive an excitatory collateral from the alpha neuron's axon as they emerge from the motor root, and are thus "kept informed" of how vigorously that neuron is firing.

They send an inhibitory axon to synapse with the cell body of the initial alpha neuron and/or an alpha motor neuron of the same motor pool.

In this way, the Renshaw cell action represents a negative feedback mechanism. A Renshaw cell may be supplied by more than one alpha motor neuron collateral and it may synapse on multiple motor neurons.

Grey matter
Grey matter (gray matter in American English) is a major component of the central nervous system, consisting of neuronal cell bodies, neuropil (dendrites and unmyelinated axons), glial cells (astrocytes and oligodendrocytes), synapses, and capillaries. Grey matter is distinguished from white matter in that it contains numerous cell bodies and relatively few myelinated axons, while white matter contains relatively few cell bodies and is composed chiefly of long-range myelinated axons. The colour difference arises mainly from the whiteness of myelin. In living tissue, grey matter actually has a very light grey colour with yellowish or pinkish hues, which come from capillary blood vessels and neuronal cell bodies.
Zymology
Zymology, also known as zymurgy, is an applied science that studies the biochemical process of fermentation and its practical uses. Common topics include the selection of fermenting yeast and bacteria species and their use in brewing, wine making, fermenting milk, and the making of other fermented foods.

Ethanol fermentation
Ethanol fermentation, also called alcoholic fermentation, is a biological process which converts sugars such as glucose, fructose, and sucrose into cellular energy, producing ethanol and carbon dioxide as by-products. Because yeasts perform this conversion in the absence of oxygen, alcoholic fermentation is considered an anaerobic process. It also takes place in some species of fish (including goldfish and carp) where (along with lactic acid fermentation) it provides energy when oxygen is scarce.

Ethanol fermentation is the basis for alcoholic beverages, ethanol fuel and bread dough rising.
Millenarianism
Millenarianism or millenarism (from Latin  millenarius 'containing a thousand' and  -ism) is the belief held by a religious, social, or political group or movement in a coming fundamental transformation of society, after which "all things will be changed". Millenarianism exists in various cultures and religions worldwide, with various interpretations of what constitutes a transformation.

These movements believe in radical changes to society after a major cataclysm or transformative event.

Millenarianist movements can be secular (not espousing a particular religion) or religious in nature, and are therefore not necessarily linked to millennialist movements in Christianity.

Traditional Christian millenarianism has roots in "Jewish apocalyptic belief, Zoroastrianism, and Babylonian astrology",
mediated through the Biblical canon.

-ism
-ism (/-ˌɪzəm/) is a suffix in many English words, originally derived from the Ancient Greek suffix -ισμός (-ismós), and reached English through the Latin -ismus, and the French -isme. It is used to create abstract nouns of action, state, condition, or doctrine, and is often used to describe philosophies, theories, religions, social movements, artistic movements, lifestyles, behaviors, scientific phenomena, or medical conditions.
Pekka Peltola
Pekka Peltola (born April 24, 1965, in Helsinki, Finland) is a Finnish former ice hockey left winger. He played in the SM-liiga for HPK, Lukko, HIFK and Ässät.

In the 1988–89 season, Peltola won the Jarmo Wasama Memorial Trophy as the SM-liiga's Rookie of the Year after scoring 58 points including 28 goals in just 43 games. He was then drafted 130th overall by the Winnipeg Jets in the 1989 NHL Entry Draft, though he never played in North America and remained with HPK.

Peltola also played in the French Élite Ligue for Brest Albatros Hockey, the Austrian Hockey League for EC KAC and the German Deutsche Eishockey Liga for the Kassel Huskies.

Brest Albatros Hockey
Brest Albatros Hockey is an ice hockey team in Brest, France. They were founded in 1991, and currently play in the FFHG Division 1, the second level of ice hockey in France. Albatros won the league championship in 1996 and 1997. The team also previously played in the Ligue Magnus.
1983 KB Cup
The 1983 KB Cup was the 10th edition of the NSWRFL Midweek Cup, a NSWRFL-organised national club Rugby League tournament between the leading clubs and representative teams from the NSWRFL, the BRL, the CRL, the QRL and the NZRL.

A total of 18 teams from across Australia and New Zealand played 17 matches in a straight knock-out format, with the matches being held midweek during the premiership season.

Queensland Rugby League
The Queensland Rugby Football League  (QRL) is the governing body for rugby league in Queensland. It is a member of the Australian Rugby League Commission (ARL Commission) and selects the members of the Queensland rugby league team.

The QRL aims to "foster, develop, extend, govern and control Rugby League Football throughout the State of Queensland". Today the QRL administers the rugby league through its regional divisions. It is also responsible for the Queensland Rugby League team. The QRL's headquarters are on Vulture Street, Woolloongabba in Brisbane.
X (Agnez Mo album)
X is the second English studio album by Indonesian pop singer Agnez Mo. This album served as Mo's first album to be promoted internationally.
It was released on 10 October 2017 by her own label, Entertainment Inc. A pop and contemporary R&B album, it consists of 10 songs including the singles "Million $ Lover", "Long As I Get Paid", and "Sorry". Danja produced most of the album.

Mo has said that X is a confessional album that she considers to be "her most personal work to date." The album's title, X, is Roman numeral for "ten", which is Mo's lucky number. She has also said that the album is a journey and all of her experiences, and that her first apartment in LA was on Tenten Wilshire Boulevard. Despite being released internationally, this album failed to enter any international chart.

Danja (music producer)
Floyd Nathaniel Hills (born February 22, 1982), known professionally as Danja (/ˈdeɪndʒə/), is an American record producer from Virginia Beach, Virginia. Beginning his career as a co-producer for fellow Virginian Timbaland, he has since produced for Lloyd Banks, Britney Spears, Dua Lipa, Usher, Keri Hilson, T.I., Nelly Furtado, Ciara, Mariah Carey, Madonna, Whitney Houston, Missy Elliott, M.I.A., Justin Timberlake, JoJo, Joe Jonas, Simple Plan, the Clutch, Pink, T-Pain, Diddy, Meek Mill, Björk, Duran Duran and Agnez Mo.
Ibn Juljul
Abu Dawud Sulayman ibn Hassan Ibn Juljul (Arabic: سليمان بن حسان ابن جلجل) (c. 944 Córdoba – c. 994) was an Andalusian Arab physician and pharmacologist of perhaps Spanish extraction. He wrote an important book on the history of medicine. His works on pharmacology were frequently quoted by physicians in Al-Andalus during the 10th and 11th centuries. Some of his works were later studied by Albertus Magnus, like De secretis, under Latinized version of his name, Gilgil.

Albertus Magnus
Albertus Magnus OP (c. 1200 – 15 November 1280), also known as Saint Albert the Great, Albert of Swabia, Albert von Bollstadt, or Albert of Cologne, was a German Dominican friar, philosopher, scientist, and bishop. He is considered one of the greatest medieval philosophers and thinkers.

Canonized in 1931, he was known during his lifetime as Doctor universalis and Doctor expertus; late in his life the sobriquet Magnus was appended to his name. Scholars such as James A. Weisheipl and Joachim R. Söder have referred to him as the greatest German philosopher and theologian of the Middle Ages. The Catholic Church distinguishes him as one of the Doctors of the Church.
Santa Fe Trail Scenic and Historic Byway
The Santa Fe Trail Scenic and Historic Byway is a 188-mile (303 km) National Scenic Byway and Colorado Scenic and Historic Byway located in Prowers, Bent, Otero, and Las Animas counties, Colorado, USA. The byway follows the Santa Fe National Historic Trail through southeastern Colorado and connects to the 381-mile (613 km) Santa Fe Trail Scenic Byway in New Mexico at Raton Pass, a National Historic Landmark at elevation 7,834 feet (2,388 m).  The byway visits Amache National Historic Site and Bent's Old Fort National Historic Site, both National Historic Landmarks, and winds between the Spanish Peaks and Raton Mesa, both National Natural Landmarks.

The byway connects with the Highway of Legends National Scenic Byway at Trinidad.

Bent County, Colorado
Bent County is a county located in the U.S. state of Colorado. As of the 2020 census, its population was 5,650. The county seat and only incorporated municipality is Las Animas. The county is named in honor of frontier trader William Bent.
Baris (ship)
A baris (Ancient Egyptian: 𓃀𓅡𓄿𓏭𓂋𓏤𓊛, romanized: bꜣjr; Ancient Greek: βᾶρις) is a type of Ancient Egyptian ship, whose unique method of construction was described by Herodotus, writing in about 450 BC. Archeologists and historians could find no corroboration of his description until the discovery of the remains of such a ship in the waters around Thonis-Heracleion in Aboukir Bay in 2003.

The ship, known as Ship 17, the first of 63 ships found in Thonis-Heraclion, measures up to 28 metres (91 feet 10 inches) in length. They were constructed using an unusual technique to join thick wooden planks together, and had a distinctive steering mechanism with an axial rudder passing through the keel of the hull. The underwater archaeological work was carried out by Franck Goddio and the European Institute for Underwater Archaeology, and the findings are being published in a book by Alexander Belov for the Oxford Centre for Maritime Archaeology.

Franck Goddio
Franck Goddio (born 1947) is a French underwater archaeologist who, in 2000, discovered the city of Thonis-Heracleion 7 km (4.3 mi) off the Egyptian shore in Aboukir Bay. He led the excavation of the submerged site of Canopus and of the ancient harbour of Alexandria (Portus Magnus), including Antirhodos Island. He has also excavated ships in the waters of the Philippines, significantly the Spanish galleon San Diego.
Minister responsible for Persons with Disabilities (Manitoba)
The minister responsible for Accessibility (formerly minister responsible for persons with disabilities) is the member of the Executive Council of Manitoba tasked with overseeing issues related to accessibility and disability in the province of Manitoba.

The executive council of Manitoba has included a minister responsible for accessibility-related issues since 2001. This position is not a full cabinet portfolio, and the responsibility has always been taken by a minister with other cabinet duties. So far, every minister to hold the position has also been Minister of Family Services and Housing.

Department of Families (Manitoba)
The Department of Families (French: Ministère des Familles; also known as Manitoba Families) is the Manitoba Government agency responsible for family-related programs and services in the province of Manitoba.

The department was created on 3 May 2016 by the newly elected government of Brian Pallister, combining the responsibilities of the former Departments of Family Services and of Housing and Community Development into a single unit.

In 2021, Rochelle Squires became the Minister of Families (French: Ministre des Familles), replacing Minister Heather Stefanson. The department also includes the Minister responsible for the Status of Women.