hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Zacopride
Zacopride is a potent antagonist at the 5-HT3 receptor and an agonist at the 5-HT4 receptor. It has anxiolytic and nootropic effects in animal models, with the (R)-(+)-enantiomer being the more active form. It also has antiemetic and pro-respiratory effects, both reducing sleep apnea and reversing opioid-induced respiratory depression in animal studies. Early animal trials have also revealed that administration of zacopride can reduce preference for and consumption of ethanol.

Zacopride was found to significantly increase aldosterone levels in human subjects for 180 minutes at a dose of 400 micrograms.  It is thought to do this by stimulating the 5-HT4 receptors on the adrenal glands.  Zacopride also stimulated aldosterone secretion when applied to human adrenal glands in vitro.  No significant changes were observed in renin, ACTH, or cortisol levels.

Zacopride has been tested in clinical trials for the treatment of schizophrenia, but was found unsuccessful.

Renin
Renin (etymology and pronunciation), also known as an angiotensinogenase, is an aspartic protease protein and enzyme secreted by the kidneys that participates in the body's renin-angiotensin-aldosterone system (RAAS)—also known as the renin-angiotensin-aldosterone axis—that increases the volume of extracellular fluid (blood plasma, lymph, and interstitial fluid) and causes arterial vasoconstriction. Thus, it increases the body's mean arterial blood pressure.

Renin is not commonly referred to as a hormone, although it has a receptor, the (pro)renin receptor, also known as the renin receptor and prorenin receptor (see also below), as well as enzymatic activity with which it hydrolyzes angiotensinogen to angiotensin I.
Midelfart family
The Midelfart family is a Norwegian patrician family of Danish origin.

The name is derived from the town of Middelfart on the island of Funen in Denmark. Its meaning is "middle way" (or more literally, "Middlefare"); it consists of the old Danish word mæthal meaning "middle" and far meaning "way," "passage" or "journey". The name originally referred to the strait Snævringen ("the narrowing"), which is the narrowest part of the Little Belt, and was subsequently applied to the settlement as well.

Niels Christensen Midelfart (died 1683) became a burgher in Trondheim. His great-grandson was the priest Hans Christian Ulrik Midelfart, a member of the 1814 Norwegian Constituent Assembly. Today the family is known for its business activities, particularly the former cosmetics group Midelfart & Co., founded in 1923. A famous member of the family is the businesswoman Celina Midelfart.

Norwegian Constituent Assembly
The Norwegian Constituent Assembly (Norwegian: Grunnlovsforsamlingen or Riksforsamlingen) is the name given to the 1814 constitutional assembly that adopted the Norwegian Constitution and formalised the dissolution of the union with Denmark. The meetings took place at the Eidsvoll Manor in the village of Eidsvoll Verk in the Eidsvoll parish in Akershus county, Norway from 10 April to 20 May 1814. In Norway, it is often just referred to as Eidsvollsforsamlingen, which means The Assembly of Eidsvoll.
Efeler
Efeler is a municipality and district of Aydın Province, Turkey. Its area is 124 km2, and its population is 303,772 (2022). The district was established as a part of the 2013 local government reorganisation from the former central district of Aydın. The name Aydın was reserved for the metropolitan municipality.

Efeler is the plural of the title Efe and it refers to the irregular soldiers from the Aegean Region who fought during the Turkish War of Independence.

Aegean region
The Aegean region (Turkish: Ege Bölgesi) is one of the 7 geographical regions of Turkey. The largest city in the region is İzmir. Other big cities are Manisa, Aydın, Denizli, Muğla, Afyonkarahisar and Kütahya.

Located in western Turkey, it is bordered by the Aegean Sea to the west, the Marmara region to the north, the Central Anatolia Region to the east, and the Mediterranean Region to the south.

Among the four coastal regions, the Aegean Region has the longest coastline.
Die Abenteuer des braven Soldaten Schwejk
Die Abenteuer des braven Soldaten Schwejk  (Translated to The adventures of the good soldier Schwejk) is a television series produced by the ORF and ZDF and directed by Wolfgang Liebeneiner. It is based on the novel Der brave Soldat Schwejk by Jaroslav Hašek and was broadcast from 1972 to 1977. Fritz Muliar played the leading role.

ORF (broadcaster)
Österreichischer Rundfunk (ORF [oːɛʁˈɛf] ⓘ; German pronunciation: [ˌøːstəʁaɪçɪʃɐ ˈʁʊntfʊŋk], lit. 'Austrian broadcasting') is the national public broadcaster and news website of Austria. Funded from a combination of television licence fee revenue and limited on-air advertising, ORF is the dominant player in the Austrian broadcast media. Austria was the last country in continental Europe after Albania to allow nationwide private television broadcasting, although commercial TV channels from neighbouring Germany have been present in Austria on pay-TV and via terrestrial overspill since the 1980s.
N'Zi Region
N'Zi Region is one of the 31 regions of Ivory Coast. Since its establishment in 2011, it has been one of the regions in Lacs District. The seat of the region is Dimbokro and the region's population in the 2021 census was 254,623. N'Zi is the only region is the country that does not border another district—it is entirely surrounded by other regions of Lacs District.

N'Zi Region is currently divided into three departments: Bocanda, Dimbokro, and Kouassi-Kouassikro.

Regions of Ivory Coast
The regions of Ivory Coast (French: régions de la Côte d'Ivoire) are the second-level subdivisions of Ivory Coast. There are 31 regions, and each region is subdivided into two or more departments, the third-level division in Ivory Coast. Two to four regions are combined to make up an autonomous district, the first-level subdivision. The autonomous districts of Abidjan and Yamoussoukro are not divided into regions.
Youssef Hourany
Youssef Hourany (25 December 1931 – 19 October 2019) was a Lebanese writer, archeologist and historian. Hourany received his diploma in philosophy, from the Lebanese University, and his PhD on the ancient philosophy of history from The Université Saint-Esprit de Kaslik (Arabic: جامعة الروح القدس – الكسليك).

Hourany taught ancient history in the Université Saint-Esprit de Kaslik from 1970 to 1977, and from 1977 to 1995 he taught philosophy and archeology in the Lebanese University, then he retired with professor grade. He kept writing books and publishing research until 2017.

Holy Spirit University of Kaslik
The Holy Spirit University of Kaslik (USEK; Arabic: جامعة الرّوح القدس – الكسليك, Jāmiʿah al-Rūḥ al-Quddus – al-Kaslīk) is a private, non-profit, Catholic university in Jounieh, Lebanon. The university was founded by the Baladites in 1950 and ratified under the new Higher Education Law of 1962. USEK is the first university in Lebanon to be established by Lebanese citizens.
Varaldsøy Municipality
Varaldsøy is a former municipality in the old Hordaland county, Norway. The 83.1-square-kilometre (32.1 sq mi) municipality existed from 1902 until its dissolution in 1965. The area is now divided between Kvinnherad Municipality and Kvam Municipality in the traditional district of Hardanger in Vestland county. The administrative centre was the village of Våge on the south part of the island of Varaldsøy. Other villages in the municipality included Mundheim and Gjermundshamn.

Prior to its dissolution in 1965, the 83.1-square-kilometre (32.1 sq mi) municipality was the 438th largest by area out of the 525 municipalities in Norway. Varaldsøy Municipality was the 502nd most populous municipality in Norway with a population of about 809. The municipality's population density was 9.7 inhabitants per square kilometre (25/sq mi) and its population had decreased by 0.9% over the previous 10-year period.

Hordaland
Hordaland (Urban East Norwegian: [ˈhɔ̂rdɑlɑn] ⓘ) was a county in Norway, bordering Sogn og Fjordane, Buskerud, Telemark, and Rogaland counties. Hordaland was the third largest county, after Akershus and Oslo, by population. The county government was the Hordaland County Municipality, which is located in Bergen. Before 1972, the city of Bergen was its own separate county, apart from Hordaland. On 1 January 2020, the county was merged with neighbouring Sogn og Fjordane county, to form the new Vestland county.
Dipak Chudasama
Dipak Nanalal Chudasama (born 20 May 1963) is a Kenyan former cricketer of Indian Gujarati origin. He was a right-handed batsman. Known as "The Doc", as he is a qualified orthodontist, Chudasama was the first Kenyan player to score an international century.

Gujarati people
The Gujarati people, or Gujaratis, are an Indo-Aryan ethnolinguistic group native to the Indian state of Gujarat. They primarily speak Gujarati, an Indo-Aryan language. Gujaratis have diaspora across India as well in a large number of countries around the world.
1994 Copenhagen Open – Doubles
David Adams and Andrei Olhovskiy were the defending champions, but lost in the first round to Yevgeny Kafelnikov and Menno Oosting.

Martin Damm and Brett Steven won the title by defeating David Prinosil and Udo Riglewski 6–3, 6–4 in the final.

David Adams (tennis)
David Dixie Adams (born 5 January 1970) is a former tennis player from South Africa. He turned professional in 1989. In his career, he won 19 doubles titles and finished runner-up an additional 33 times, including at the French Open in 1992. He achieved a career-high doubles ranking of world No. 9 in February 1994.

Adams participated in six Davis Cup ties for South Africa between 1997 and 2003, posting a 4–2 record, all in doubles.

Adams won two Grand Slam titles in mixed doubles, both with fellow South African Mariaan de Swardt, taking the Australian Open title in 1999 and the French Open title in 2000.
Bór Kunowski
Bór Kunowski (Polish pronunciation: [ˈbur kuˈnɔfskʲi]) is a village in the administrative district of Gmina Brody, within Starachowice County, Świętokrzyskie Voivodeship, in south-central Poland. It lies approximately 4 km (2 mi) east of Brody, 15 km (9 mi) east of Starachowice, and 49 km (30 mi) east of the regional capital Kielce.

Starachowice
Starachowice [staraxɔˈvʲit͡sɛ] ⓘ is a city in southeastern Poland (historic Lesser Poland), with 49,513 inhabitants (31.12.2017). It is the capital of Starachowice County in the Świętokrzyskie Voivodeship. It is situated upon the River Kamienna, a tributary of the Vistula River, among hills and forests.
Cricket Paint
Cricket Paint was a second generation 1-bit (black and white) painting software program for the Apple Macintosh by Cricket Software. It followed MacPaint and was a competitor to Silicon Beach Software's SuperPaint. Like SuperPaint it was an early attempt to combine the separate graphic methods of bitmap and  vector graphics.
Cricket Software already had a vector-only package called CricketDraw.
The way it achieved this dualism was with a feature called WetPaint. This allowed the user to draw vector graphics and modify them in an object-oriented way like in Apple's MacDraw, for example, changing the size, stroke and fill. When satisfied, the user could click outside the object and Cricket Paint would convert the vector graphic into a bitmap and place it on the canvas, in a destructive edit.
This package had some extra tools not found in MacPaint or MacDraw, such as the Spiral and Starburst, which drew radial lines.

It was also released for Microsoft Windows.

PCMag
PC Magazine (shortened as PCMag) is an American computer magazine published by Ziff Davis. A print edition was published from 1982 to January 2009. Publication of online editions started in late 1994 and continues as of 2026.
Estefania García
Estefania Priscila García Mendoza (born 13 May 1988, Portoviejo) is an Ecuadorian judoka. At the 2012 Summer Olympics she competed in the Women's 63 kg, but was defeated in the second round.

She competed in the women's 63 kg division at the 2016 Summer Olympics in Rio de Janeiro. She defeated Mamadama Bangoura of Guinea in the first round and was then defeated by Kathrin Unterwurzacher of Austria in the next round. She was the flag bearer for Ecuador during the Parade of Nations.

She represented Ecuador at the 2020 Summer Olympics in Tokyo, Japan.

2016 Summer Olympics Parade of Nations
During the Parade of Nations within the Rio de Janeiro 2016 Summer Olympics opening ceremony, athletes and officials from each participating team marched in the Maracanã Stadium preceded by their flag and placard bearer. Each flag bearer had been chosen either by the team's National Olympic Committee or by the athletes themselves.
Fyrby Runestone
The Fyrby Runestone, which is designated as Sö 56 in the Rundata catalog, is a Viking Age memorial runestone located in Fyrby, which is about 15 kilometers south of Flen, Södermanland County, Sweden, and in the historic province of Södermanland.

Memorial
A memorial is an object or place which serves as a focus for the memory or the commemoration of something, usually an influential, deceased person or a historical, tragic event. Popular forms of memorials include landmark objects such as homes or other sites, or works of art such as sculptures, statues, fountains or parks. Larger memorials may be known as monuments.
Trina de Moya
María de los Ángeles Trinidad de Moya Pérez (January 13, 1863 – March 13, 1941), known as just Trina de Moya, was a Dominican Republic poet and writer. She served as the First Lady of the Dominican Republic as the wife of President Horacio Vásquez for three nonconsecutive terms. De Moya was the first Dominican presidential wife to be called "first lady", a title which came into widespread public usage during her third tenure from 1924 to 1930.

Trina de Moya's best known literary works include the Dominican version of Himno a la Madre, a Latin American hymn dedicated to mothers, which premiered on May 30, 1926. She often published her poetry and other writings under the literary pseudonyms "T. Colombina" and "Angela".

Tamboril, Dominican Republic
Tamboril is a municipality (municipio) of the Santiago province in the Dominican Republic. Tamboril is situated in the northeast part of the province, at the foot of the Cordillera Septentrional mountains, at 230 meters above sea level. The municipality has an area of 71.4 km2; it borders Puerto Plata Province (North), Licey (South), Espaillat Province (East), and Santiago (West).
Rineen ambush
The Rineen ambush was an ambush carried out by the Mid Clare Brigade of the Irish Republican Army (IRA) on 22 September 1920, during the Irish War of Independence. The attack took place at Drummin Hill in the townland of Drummin, near the hamlet of Rineen (or Rinneen), County Clare.

The IRA's Mid-Clare Brigade attacked a Royal Irish Constabulary (RIC) lorry, killing six officers. Shortly afterwards, the IRA encountered ten lorry-loads of British Army soldiers, who had been sent out on a separate patrol looking for a missing magistrate. However, the IRA held off this attack long enough to flee the scene in an orderly retreat and sustained only two wounded.

In reprisal for the ambush, the RIC Auxiliaries and British military raided three local villages, killed five civilians and burnt 16 houses and shops in the surrounding area.

County Clare
County Clare (Irish: Contae an Chláir) is a county in the province of Munster in the  Southern part of Ireland, bordered on the west by the Atlantic Ocean. Clare County Council is the local authority. The county had a population of 127,938 at the 2022 census. The county seat and largest settlement is Ennis.
9th Manitoba Legislature
The members of the 9th Manitoba Legislature were elected in the Manitoba general election held in January 1896. The legislature sat from February 6, 1896, to November 16, 1899.

The Liberals led by Thomas Greenway formed the government.

Rodmond Roblin served as Leader of the Opposition.

Finlay McNaughton Young served as speaker for the assembly.

There were four sessions of the 9th Legislature:

James Colebrooke Patterson was Lieutenant Governor of Manitoba.

James Colebrooke Patterson
James Colebrooke Patterson, PC (1839 – February 17, 1929) was a Canadian politician.  He served as a federal cabinet minister from 1892 to 1895 and as the sixth Lieutenant Governor of Manitoba from 1895 to 1900.
Magallu
Magallu is a village in NTR district of the Indian state of Andhra Pradesh. It is located in Nandigama mandal of Vijayawada revenue division. It is one of the villages in the mandal to be a part of Andhra Pradesh Capital Region.

NTR district
NTR district is a district in coastal Andhra Region in the Indian state of Andhra Pradesh. The district headquarters is located at Vijayawada. The district is named after former Chief Minister of Andhra Pradesh N. T. Rama Rao. The district shares boundaries with  Guntur,  Palnadu,  Krishna,  Eluru,  Khammam and  Suryapet districts.
Critics' Choice Super Award for Best Actor in a Horror Series
The Critics' Choice Super Award for Best Actor in a Horror Series, Limited Series or Made-for-TV Movie is an award presented by the Critics Choice Association to the best performance by an actor in a horror television series or TV Movie.

This award was first presented in 2021 to Jensen Ackles for his role as Dean Winchester on Supernatural. The most nominated actor in this category is Mike Colter with four nominations.

The current recipient of the award is Pedro Pascal for his role as Joel Miller in The Last of Us.

Dean Winchester
Dean Winchester is one of the two protagonists from the American drama television series Supernatural, along with his younger brother Sam. He is portrayed primarily by Jensen Ackles. Other versions of the character having been portrayed by Hunter Brochu (toddler), Ridge Canipe (child), Nicolai Lawton-Giustra (pre-teen), Brock Kelly and Dylan Everett (teen), and Chad Everett (elderly).
Sergei Mosyagin
Sergei Mosyagin (Russian: Сергей Михайлович Мосягин) was a Soviet footballer and football coach.

In 1970s after winning the 1977 FIFA World Youth Championship, he was awarded honorary titles of Merited Coach of the Soviet Union and Merited Coach of the Russian SFSR (Russia).

1977 FIFA World Youth Championship
The 1977 FIFA World Youth Championship was the inaugural staging of the FIFA World Youth Championship, hosted by Tunisia from 27 June to 10 July 1977, in three venues — Tunis, Sousse and Sfax. The 28 matches played were the smallest number in tournament history. The USSR U20s defeated Mexico U20s in a penalty shootout, in the final held at Tunis's Stade El Menzah.

The Tournament Committee was chaired by FIFA Vice-President Harry Cavan, who had spearheaded the creation of the World Youth Championship.
King of the Arena
King of the Arena is a 1933 American pre-Code
Western film written and directed by Alan James. The film stars Ken Maynard, Lucile Browne, John St. Polis, Bob Kortman, Michael Visaroff and James A. Marcus. The film was released on June 1, 1933, by Universal Pictures.

Alan James
Alan James (March 23, 1890 – December 30, 1952) was an American film director and screenwriter.

He was born in Port Townsend, Washington, as Alan J. Neitz.

He directed more than 70 films between 1916 and 1943. He also wrote for more than 60 films between 1916 and 1951. Many of those films were Westerns.

He died in Hollywood, California.
Dioscoride Lanza
Dioscoride Lanza (24 April 1898 – 28 October 1977) was an Italian racing driver. He entered 30 races between 1936 and 1955 – of which he started 24 – most of them in a Maserati. He submitted an entry in advance of the 1946 Indianapolis 500, but failed to appear for the event. His best result was a fourth place at the Coppa Ciano Junior.

Maserati
Maserati S.p.A. (Italian: [mazeˈraːti]) is an Italian luxury car manufacturer. Established on 1 December 1914 in Bologna, Italy, the company's headquarters are now in Modena, and its emblem is a trident. The company has been owned by Stellantis since 2021.
Cindy O'Callaghan
Cindy O'Callaghan (born 18 October 1956) is an Irish-born British psychologist and former actress. Her acting career began in her adolescence, when she was chosen to play the part of Carrie Rawlins in the Disney feature film Bedknobs and Broomsticks in 1971. She has appeared in a wide range of television programmes and films since, including BBC's EastEnders, where she played Andrea Price for several stints in the 1990s. Her last credited role was in 2001, and she has since given up acting to become a child psychologist.

Rumpole of the Bailey
Rumpole of the Bailey is a British television series created and written by the British writer and barrister John Mortimer. It stars Leo McKern as Horace Rumpole, a middle-aged London barrister who defends a broad variety of clients, often underdogs. The popularity of the TV series led to the stories being presented in other media, including books and radio.

The "Bailey" of the title is a reference to the Central Criminal Court, the "Old Bailey".
Eftim Bogoev
Eftim Bogoev (Macedonian: Ефтим Богоев; born November 2, 1980) is a Macedonian professional basketball player born in Strumica. He was last under contract with  Strumica. He  is 1.85 m (6 ft 1 in) in height and plays the guard position.

Cup of Macedonia
The Basketball Cup of Macedonia (Macedonian: Кошаркарски куп на Македонија), is an elimination basketball tournament held annually. It is the second most important national title in Macedonian basketball after the Macedonian First League. Currently, MZT Skopje  holds the record for most titles won - 14.
Council of Reims (1148)
In 1148, a synodical council was called by Pope Eugene III to consider a variety of issues for the Church. Originally the summons to the council went out in October 1147 and it was supposed to be held in February 1148 at Trier,  but conditions there were such that it was moved to Reims. A number of the bishops and other Churchmen who had been  convoked did not attend and Eugene suspended many of the non-attendees, excepting the other Churchmen of Italy, who were excused. The council convened on 21 March 1148 and is said to have lasted 11 days in total, which would give an end date of 1 April 1148. However, it is possible that it was shorter, given that the large increase in the population of Reims would have strained the town's resources.

After the conclusion of the council, Eugene held a consistory trial of Gilbert of Poitiers, the Bishop of Poitiers, who was accused of heretical teachings. In the end, Gilbert was allowed to return to his see.

Pope Eugene III
Pope Eugene III (Latin: Eugenius III; c. 1080 – 8 July 1153), born Bernardo, called Bernardo da Pisa, was head of the Catholic Church and ruler of the Papal States from 15 February 1145 to his death in 1153. He was the first Cistercian to become pope. In response to the fall of Edessa to the Muslims in 1144, Eugene proclaimed the Second Crusade. The crusade failed to recapture Edessa, which was the first of many failures by the Christians in the crusades to recapture lands won in the First Crusade. He was beatified in 1872 by Pope Pius IX.