hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
2'-5'-oligoadenylate synthase
In molecular biology, 2'-5'-oligoadenylate synthetase (2-5A synthetase) is an enzyme (EC 2.7.7.84) that reacts to interferon signal. It is an antiviral enzyme that counteracts viral attack by degrading RNAs, both viral and host. The enzyme uses ATP in 2'-specific nucleotidyl transfer reactions to synthesize 2'-5'-oligoadenylates, which activate latent ribonuclease (RNase-L), resulting in degradation of viral RNA and inhibition of virus replication.

The C-terminal half of 2'-5'-oligoadenylate synthetase, also referred to as domain 2 of the enzyme, is largely alpha-helical and homologous to a tandem ubiquitin repeat. It carries the region of enzymatic activity between at the extreme C-terminal end.

Nucleotidyltransferase
Nucleotidyltransferases are transferase enzymes of phosphorus-containing groups, e.g., substituents of nucleotidylic acids or simply nucleoside monophosphates. The general reaction of transferring a nucleoside monophosphate moiety from A to B, can be written as:

A-P-N + B  A + B-P-N

For example, in the case of polymerases, A is pyrophosphate and B is the nascent polynucleotide.
They are classified under EC number 2.7.7 and they can be categorised into:

Uridylyltransferases, which transfer uridylyl- groups

Adenylyltransferases, which transfer adenylyl- groups

Guanylyltransferases, which transfer guanylyl- groups

Cytitidylyltransferases, which transfer cytidylyl- groups

Thymidylyltransferases, which transfer thymidylyl- groups
Nysted
Nysted is a town in Guldborgsund Municipality in Region Zealand on the southeastern coast of the island of Lolland in south Denmark. Nysted is located on the southern coast of Lolland, and has a population of 1,229 (1 January 2025).

Region Zealand
Region Zealand (Danish: Region Sjælland) is an administrative region of Denmark. It is one of the five classified NUTS-2 statistical regions of Denmark. It was established on 1 January 2007 as part of the 2007 Danish Municipal Reform, which abolished the traditional counties ("amter"). The region incorporates the southernmost parts of the country, and encompasses an area of 7,223 km2 (2,789 sq mi).

Zealand will merge with the Capital Region of Denmark on 1 January 2027 to create the Region of Eastern Denmark.

The region shares the island of Sjælland (Zealand) with the neighbouring Capital Region of Copenhagen. The region also includes the islands of Lolland, Falster, and Møn. It incorporates the provinces of Østsjælland and Vest-og Sydsjælland, which consists of 17 municipalities. With a population of just over 0.85 million, it is the second least populated of the all the regions in Denmark. The largest city is Roskilde.
Tracey Stern
Tracey Stern is an American television writer and producer.

Stern made her television debut writing for the first two seasons of ER. She has also worked as a writer on Pacific Blue, Sports Night, Angel, Law & Order: Special Victims Unit, Leap Years, Touching Evil, Desperate Housewives, The Book of Daniel, and Angela's Eyes. Stern has also worked as a producer for Sports Night, Angel, Desperate Housewives and Angela's Eyes. The first season of Desperate Housewives was nominated for an Emmy award for Outstanding Drama Series at the 2005 awards. The producers shared the nomination for their work on the season.

Primetime Emmy Award for Outstanding Drama Series
The Primetime Emmy Award for Outstanding Drama Series is an award presented since 1951 by the Academy of Television Arts & Sciences (ATAS). The award goes to the producers of the series. The award is often cited as one of the "main awards" at the Emmys ceremonies.
Khoso caretaker government
The Khoso caretaker government was the Pakistani caretaker federal cabinet that was sworn into office on 2 April 2013. On 24 March 2013, Mir Hazar Khan Khoso was nominated by the Election Commission as the Caretaker Prime minister, out of four nominees coming from both the opposition and the dissolved government. Khoso was sworn into office on 25 March 2013.

Caretaker Prime Minister of Pakistan
The caretaker prime minister of Pakistan (Urdu: نگران وزیر اعظم پاکستان) is the acting head of the Caretaker Government in Pakistan following the dissolution of the National Assembly. The purpose of this post is to ensure free and fair elections are held. The most recent caretaker prime minister was Anwaar ul Haq Kakar, who took office on 14 August 2023, after the National Assembly was dissolved; he served until 4 March 2024.
Long Wall of Quảng Ngãi
The Long Wall of Quang Ngai (Vietnamese: Trường lũy Quảng Ngãi), Truong luy, or the Great Wall of Vietnam is a 127.4-kilometre (79.2 mi) rampart extending from Vietnam's Quảng Ngãi Province in the north to Binh Dinh Province in the south. The defensive wall was built by the Nguyễn dynasty as a demarcation line against the Đá Vách (H're people). It is the longest monument in Southeast Asia.

Bình Định province
Bình Định was formerly a northern coastal province in the South Central Coast region, the Central of Vietnam. It borders Quảng Ngãi to the north, Phú Yên to the south, Gia Lai to the west and the South China Sea to the east.

Bình Định province has an area of 6,066.40 km2 (2,342.25 mi2), comprising 11 district-level sub-divisions, with a population of over 1.5 million people as of 2023. The province is known for its scenery and beaches. There are also a number of Cham structures. Majority of the province is covered by mountains or hills. Its capital Quy Nhon served as the capital of the historic Tây Sơn dynasty. Economically the province has the most productive primary sector in the South Central Coast region, mostly because of its large output of rice, coconuts and its strong livestock, forestry and fishing sectors.

On June 12, 2025, Bình Định was incorporated into Gia Lai province.
Eva Rutarová
Eva Rutarová (born (1989-09-14)14 September 1989) is a Czech female volleyball player. She is part of the Czech Republic women's national volleyball team.

She participated in the 2014 FIVB Volleyball World Grand Prix, and in the 2015 FIVB Volleyball World Grand Prix.
On club level she played for SK UP Olomouc in 2014.

2015 FIVB Volleyball World Grand Prix
The 2015 FIVB Volleyball World Grand Prix was the 23rd edition of the annual women's international volleyball tournament played by 28 countries from 26 June to 2 August 2015. This was the first time that the Group 1 final round was held in Omaha, Nebraska, United States.
Appenzell District
Appenzell District is a district of the canton of Appenzell Innerrhoden in Switzerland. It has a population of 5,793 (as of December 2020). The area of Appenzell is 16.88 km2 (7 sq mi). The district of Appenzell consists of a part of the village Appenzell, as well as Rinkenbach, Kau and Meistersrüte.

St. Gallen
St. Gallen is a Swiss city and the capital of the canton of St. Gallen. It evolved from the hermitage of Saint Gall, founded in the 7th century. Today, it is a large urban agglomeration (with around 167,000 inhabitants in 2019) and represents the center of eastern Switzerland. Its economy consists mainly of the service sector. The city is home to the University of St. Gallen, one of the best business schools in Europe.

The main tourist attraction is the Abbey of Saint Gall, a UNESCO World Heritage Site. The Abbey's renowned library contains books from the 9th century. The official language of St. Gallen is (the Swiss variety of Standard) German, but the main spoken language is the local variant of Alemannic Swiss German. The city has good transport links to the rest of the country and to neighbouring Germany and Austria. It also functions as the gate to the Appenzellerland.
Herpes (journal)
Herpes: The Journal of the IHMF was a triannual peer-reviewed medical journal published by Cambridge Medical Publications and the official journal of the International Herpes Management Forum. It was indexed from 1997 in Scopus and from 2001 in Index Medicus/MEDLINE/PubMed, until 2009, when the last issue was published. Articles were usually solicited and publication was supported by an educational grant from GlaxoSmithKline and 3M Pharmaceuticals.

Index Medicus
Index Medicus (IM) was a comprehensive bibliographic index of life science, biomedical science, and medical research articles, published from 1879 to 2004. Medical history experts have said of Index Medicus that it is “America's greatest contribution to medical knowledge.” It was published as a print index until 2004; beginning in the 1960s, it was also published as an electronic database, MEDLARS. Index Medicus content from 1940s to 2004 was incorporated into MEDLINE and PubMed; older medical literature, however, is not electronically available. Today, the title Index Medicus is also used to refer to a curated subset of Pubmed.
Sergio Rojas Carmona
Sergio Rojas Carmona (born 24 January 1968) is a Mexican politician from the Party of the Democratic Revolution. From 2006 to 2009 he served as a Deputy of the LX Legislature of the Mexican Congress representing the State of Mexico.

Party of the Democratic Revolution
The Party of the Democratic Revolution (Spanish: Partido de la Revolución Democrática [paɾˈtiðo ðe la reβoluˈsjon demoˈkɾatika], PRD) is a state-level social democratic political party in Mexico (previously national, until 2024). The PRD originated from the Democratic Current, a political faction formed in 1986 from the Institutional Revolutionary Party (PRI). The PRD was formed after the contested general election in 1988, which the PRD's immediate predecessor, the National Democratic Front, believed was rigged by the PRI. This sparked a movement away from the PRI's authoritarian rule.

As of 2023, the PRD was a member of the Fuerza y Corazón por México (Strength and Heart for Mexico) coalition. Internationally, the PRD was a member of the Progressive Alliance. The members of the party are known colloquially in Mexico as Perredistas. In 2024, the party failed to reach the necessary percentage of votes to keep its registration as a national political party.
Avenue U station (IND Culver Line)
The Avenue U station is a local station on the IND Culver Line of the New York City Subway, located at the intersection of Avenue U and McDonald Avenue in Gravesend, Brooklyn. It is served by the F train at all times and the <F> train during rush hours in the reverse peak direction.

Culver Shuttle
The Culver Shuttle was a New York City Subway shuttle, running along a remnant of the BMT Culver Line, most of which is now the IND Culver Line. The shuttle was originally part of the Brooklyn-Manhattan Transit Corporation (BMT)'s 5 service, providing through service on the Culver Line between Coney Island and Manhattan. The F train is the current successor to Culver Line service. The line had 1,000 riders a day during its final month of service in 1975.
Lost in Panic Cruise
Lost in Panic Cruise is a 2011 Chinese suspense thriller and sequel to Lost in Panic Room. The film was directed by Zhang Fanfan and written by Xiao Yu, starring Alec Su, Annie Wu, Cica Zhou, Yang Kun, and Ni Hongjie. The film was released in China on 27 October 2011.  It is the sequel to the 2010 film "Lost in Panic Room."

Suspense
Suspense is a state of anxiety or excitement caused by mysteriousness, uncertainty, doubt, or undecidedness.  In a narrative work, suspense is the audience's excited anticipation about the plot or conflict (which may be heightened by a violent moment, stressful scene, puzzle, mystery, etc.), particularly as it affects a character for whom the audience feels sympathy. However, suspense is not exclusive to narratives.
Japanese ship Yamato
Two ships in service with the Imperial Japanese Navy were named Yamato:

Japanese battleship Yamato, was the lead ship of her class of battleships, launched in 1940 and sunk in 1945

Japanese corvette Yamato, was a Katsuragi-class corvette, launched in 1885, decommissioned in 1935 and sank in 1945.

Japanese corvette Yamato
Yamato (大和, Yamato) was the second vessel in the Katsuragi class of three composite hulled, sail-and-steam corvettes of the early Imperial Japanese Navy. It was named for Yamato province, the old name for Nara prefecture and the historic heartland of Japan. The name was used again for the World War II battleship Yamato, commissioned in 1941.
Ben 10: Protector of Earth
Ben 10: Protector of Earth is an action-adventure video game  developed by High Voltage Software and published by D3 Publisher and is based on the animated television series Ben 10. This is the second Ben 10 game following the HyperScan game, is the first official game in the franchise, and it was released for the PlayStation 2, PlayStation Portable, the Nintendo DS and the Nintendo Wii in late 2007.

D3 Publisher
D3 Publisher Inc. is a Japanese video game developer and publisher founded on February 5, 1992. The company is known for the Simple series of budget-priced video games. Their games have been released for the Game Boy Advance, Nintendo DS, Nintendo 3DS, Nintendo Switch, PlayStation Portable, PlayStation Vita, PlayStation 2, PlayStation 3, PlayStation 4, PlayStation 5, GameCube, Wii, Xbox, Xbox 360, Wii U, Android, and iOS.
R. Daniel Kelemen
Roger Daniel Kelemen is a scholar of law and political science. He is McCourt Chair at the McCourt School of Public Policy at Georgetown University, having previously been on the faculties of Rutgers University and the University of Oxford. He is also a Senior Associate (Non-Resident) in the Europe, Russia, and Eurasia Program of the Center for Strategic and International Studies. His 2011 book Eurolegalism: The Transformation of Law and Regulation in the European Union was named best book by the European Union Studies Association.

McCourt School of Public Policy
The McCourt School of Public Policy at Georgetown University is located in Washington, D.C. The McCourt School offers one undergraduate degree, five master's degree programs, nine dual degrees, global learning opportunities in a range of destinations, and certificate and other executive education programming. The McCourt School has 52 full-time faculty members, 54 research faculty members and fellows, more than 100 affiliated faculty members, and approximately 500 enrolled students across the various degree and executive education programs.

In the summer of 2024, the McCourt School relocated to 125 E Street NW at Georgetown's Capitol Campus. Formerly known as the Georgetown Public Policy Institute (GPPI), the McCourt School became Georgetown University's ninth school in October 2013 as a result of a $100 million gift from Georgetown University alumnus Frank McCourt.
Begonia hispida
Begonia hispida, the piggyback begonia (a name only applied to individuals with leaflets), is a species of flowering plant in the family Begoniaceae, native to southeastern and southern Brazil. They are occasionally cultivated due to their "piggyback" leaflets which grow directly from veins in the main leaves. The piggyback mutation is also seen in Arabidopsis.

Arabidopsis thaliana
Arabidopsis thaliana, the thale cress, mouse-ear cress or arabidopsis, is a small plant from the mustard family (Brassicaceae), native to Eurasia and Africa. Commonly found along the shoulders of roads and in disturbed land, it is generally considered a weed.

A winter annual with a relatively short lifecycle, A. thaliana is a popular model organism in plant biology and genetics. For a complex multicellular eukaryote, A. thaliana has a relatively small genome of around 135 megabase pairs. It was the first plant to have its genome sequenced, and is an important tool for understanding the molecular biology of many plant traits, including flower development and light sensing.
Dipterocarpus condorensis
Dipterocarpus condorensis is a species of plant in the evergreen or semi-evergreen family Dipterocarpaceae.

It is an emergent tree, up to 50 m tall, in mixed dipterocarp forest on dry ridges. It is found in Sumatra, coastal Peninsular Malaysia, Singapore, and Borneo, the Philippines, and Vietnam. It is a medium hardwood sold under the trade names of Keruing. It was formerly most abundant along the coastal hills on sandy soils, but is endangered due to land conversion. D. condoriensis is found in at least one protected area (Sepilok Forest Reserve).

Land development
Land development is the alteration of landscape in any number of ways, such as:

Changing landforms from a natural or semi-natural state for a purpose such as agriculture or housing

Subdividing real estate into lots, typically for the purpose of building homes

Real estate development or changing its purpose, for example by converting an unused factory complex into a condominium
Ikaria Study
The Ikaria Study is a small-scale survey by  the University of Athens School of Medicine of the diet and lifestyle of  Greek people over age 80 on the island of Ikaria. The study found that the Ikarian diet includes olive oil, red wine, fish, coffee, herbal tea, honey, potatoes, garbanzo beans, black-eyed peas, lentils, and a  limited amount of meat, sugar and dairy products,  except goat milk.

The data showed that people on Ikaria achieved successful aging by reducing emotional and cognitive dysfunction while sustaining physical activities throughout old age. It also hypothesized that noon siesta and engagement in social activities are factors that contributed to the Ikarians' longevity.

Chickpea
The chickpea or chick pea (Cicer arietinum) is an annual legume of the family Fabaceae, subfamily Faboideae, cultivated for its edible seeds. Its different types are variously known as gram, Bengal gram, chana dal (চানা ডাল), garbanzo, garbanzo bean, or Egyptian pea. It is one of the earliest cultivated legumes, the oldest archaeological evidence of which was found in Syria.

Chickpeas are high in protein. The chickpea is a key ingredient in Mediterranean and Middle Eastern cuisines, used in hummus, and, when soaked and coarsely ground with herbs and spices, then made into patties and fried, falafel. As an important part of Indian cuisine, it is used in salads, soups, stews, and curries. In 2023, India accounted for 75% of global chickpea production.
Procollagen galactosyltransferase
In enzymology, a procollagen galactosyltransferase (EC 2.4.1.50) is an enzyme that catalyzes the chemical reaction

UDP-galactose + procollagen 5-hydroxy-L-lysine  UDP + procollagen 5-(D-galactosyloxy)-L-lysine

Thus, the two substrates of this enzyme are UDP-galactose and procollagen 5-hydroxy-L-lysine, whereas its two products are UDP and procollagen 5-(D-galactosyloxy)-L-lysine.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases.  The systematic name of this enzyme class is UDP-galactose:procollagen-5-hydroxy-L-lysine D-galactosyltransferase. Other names in common use include hydroxylysine galactosyltransferase, collagen galactosyltransferase, collagen hydroxylysyl galactosyltransferase, UDP galactose-collagen galactosyltransferase, uridine diphosphogalactose-collagen galactosyltransferase, and UDPgalactose:5-hydroxylysine-collagen galactosyltransferase.  This enzyme participates in lysine degradation.

Uridine diphosphate
Uridine diphosphate, abbreviated UDP, is an organic compound. It is an ester of pyrophosphoric acid with the nucleoside uridine. UDP consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase uracil.

UDP is an important factor in glycogenesis. Before glucose can be stored as glycogen in the liver and muscles, the enzyme UDP-glucose pyrophosphorylase forms a UDP-glucose unit by combining glucose 1-phosphate with uridine triphosphate, cleaving a pyrophosphate ion in the process. Then, the enzyme glycogen synthase combines UDP-glucose units to form a glycogen chain. The UDP molecule is cleaved from the glucose ring during this process and can be reused by UDP-glucose pyrophosphorylase.
Chesapeake and Albemarle Railroad
Trains portal

Railways portal

The Chesapeake and Albemarle Railroad (reporting mark CA) is a short-line railroad that operates 78 miles (126 km) of track from Chesapeake, Virginia, to Edenton, North Carolina.

Shortline railroad
A shortline railroad is a small or mid-sized railroad company that operates over a relatively short distance relative to larger, national railroad networks. The term is used primarily in the United States and Canada. In the former, railroads are categorized by operating revenue, and most shortline railroads fall into the Class III or Class II categorization defined by the Surface Transportation Board.
2025 Chennai Open Challenger – Doubles
Saketh Myneni and Ramkumar Ramanathan were the defending champions but lost in the final to Shintaro Mochizuki and Kaito Uesugi.

Mochizuki and Uesugi won the title after defeating Myneni and Ramanathan 6–4, 6–4 in the final.

Shintaro Mochizuki
Shintaro Mochizuki (Japanese: 望月 慎太郎, Mochizuki Shintarō, born 2 June 2003) is a Japanese professional tennis player.
He has an ATP career-high singles ranking of world No. 92 on 10 November 2025 and a doubles ranking of No. 371 achieved on 18 October 2021. He is currently the No. 1 Japanese player. Mochizuki became the first Japanese male player in history to win a Grand Slam boys’ singles title at 2019 Wimbledon. Mochizuki achieved a career-high Junior ITF combined ranking of No. 1 on 15 July 2019.
Polícia de Segurança Pública
The Polícia de Segurança Pública MHTE (PSP; Public Security Police) is the national civil police force of Portugal. Part of the Portuguese security forces, the mission of the PSP is to defend Republican democracy, safeguarding internal security and the rights of its citizens. Despite many other functions, the force is generally known for policing urban areas with uniformed police officers, while rural areas are normally policed by National Republican Guard (GNR), the country's national gendarmerie force. PSP is focused in preventive policing, only investigating minor crimes. Investigation of serious crimes falls under the Judicial Police responsibility, which is a separate agency.

Since October 2023, the PSP is now in charge of controlling the Portuguese borders (alongside the GNR), with the dissolution of the Foreigners and Borders Service.

Military Order of the Tower and Sword
The Military Order of the Tower and of the Sword, of Valour, Loyalty and Merit (Portuguese: Ordem Militar da Torre e Espada, do Valor, Lealdade e Mérito), before 1917 the ancient and most noble order of the Tower and of the Sword, of valour, loyalty and merit (A antiga e muito nobre ordem da Torre e Espada, do valor, lealdade e mérito), is one of the four former ancient Portuguese military orders and the pinnacle of the Portuguese honours system. It was created by King Afonso V in 1459. The order may be bestowed on people or on Portuguese municipalities.