hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Thrombolytic Science International
Thrombolytic Science, LLC (TSI) is a private, clinical stage biopharmaceutical company that was founded in 2006 based on the research of Harvard scientist Victor Gurewich into the potential use of prourokinase to break up blood clots.  Gurewich co-founded the company and the founding CEO is  business person Alexis Wallace.

TSI's lead drug  candidate is a synergistic sequential dual therapy combination of mutant prourokinase (the precursor form of urokinase) and a small dose of tPA [Tissue Plasminogen Activator]. TSI is developing its dual therapy as a potential treatment for conditions caused by blood clots, initially for ischemic stroke and heart attacks.

The company completed a Phase I trial in The Netherlands in 2017.

The company raised $8 million by 2012 mostly from an undisclosed angel investor.

Drug development
Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the process of drug discovery. It includes preclinical research on microorganisms and animals, filing for regulatory status, such as via the United States Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and may include the step of obtaining regulatory approval with a new drug application to market the drug. The entire process—from concept through preclinical testing in the laboratory to clinical trial development, including Phase I–III trials—to approved vaccine or drug typically takes more than a decade.
Frederick Schwarz
Fred, Frederic, Frederick, Friedrich, or Fritz Schwarz, Schwartz, Shwarz, or Shwartz could refer to:

Frederick August Otto Schwarz (1836–1911), German-born American toy retailer 
FAO Schwarz, company founded by Frederick August Otto Schwarz

Frederick A.O. Schwarz Jr. (born 1935), American attorney and great-grandson of Frederick August Otto Schwarz

Fred Schwarz (1913–2009), Australian physician and political activist

Friedrich Schwarz (1880–?), German fencer

Fritz Schwarz (1899–?), German bobsledder

Fritz Schwarz-Waldegg (born Friedrich Schwarz, 1889–1942), Austrian painter

Frederic Schwartz (1951–2014), American architect and city planner

Fritz Schwarz
Fritz Schwarz (14 August 1899 - 6 November 1961) was a German bobsledder who competed in the 1930s. He won two medals at the 1934 FIBT World Championships with a gold in the four-man and a silver in the two-man event.

Schwarz also finished seventh in the four-man event at the 1936 Winter Olympics in Garmisch-Partenkirchen.
FC Tskhinvali
FC Tskhinvali is a defunct Georgian football club, which in mid-2010s spent four seasons in the top tier of the national league.

Despite the name, due to the enduring Georgian–Ossetian conflict they were unable to host their opponents in the city of Tskhinvali, playing home games instead in Georgian-controlled areas, mostly in Gori, Tbilisi and Rustavi.

In early 2020, the club was disqualified from Liga 3 after their failure to solve a severe financial crisis.

Several times the club has undergone name changes:

Spartaki until 1990

Liakhvi from 1990 to 2003

Tskhinvali from 2003 to 2007

Spartaki from 2007 to 2015

Tskhinvali after 2015

Liga 3 (Georgia)
Liga 3 (Georgian: ლიგა 3), organized by the Georgian Football Federation, is the third division of professional football in Georgia. Introduced for the 2017 season with the launch of the Erovnuli Liga, it is a rebrand of the former Meore Liga (the Second League).

The current holders are Shturmi.
Bad Omen (film)
Bad Omen is a 2020 Canadian short drama film, directed by Salar Pashtoonyar. The film stars Fereshta Afshar as Pari, a widowed tailor in Kabul who must find the money to pay for a pair of prescription glasses to keep her job, despite Afghan culture's social stigmatization of widows.

Made as Pashtoonyar's thesis project for his film degree at York University, the film won the Lindalee Tracey Award for emerging filmmakers at the 2020 Hot Docs Canadian International Documentary Festival. The film had its public premiere at the 2020 Vancouver International Film Festival, where it won the award for Best Canadian Short Film.

It received a Canadian Screen Award nomination for Best Live Action Short Drama at the 9th Canadian Screen Awards, and won a Bronze Medal from the Student Academy Awards in 2021.

9th Canadian Screen Awards
The 9th Canadian Screen Awards were presented by the Academy of Canadian Cinema and Television from 17–20 May 2021 to honour achievements in Canadian film, television, and digital media production in 2020. The presentations were held as a series of virtual events due to the COVID-19 pandemic.

Most nominations were announced on 3 March 2021; however, the nominations and winners in sports broadcasting categories were announced at a later date. In the film categories, the film Blood Quantum received the most award nominations (10), and ultimately the most wins (6), while in the television categories, Schitt's Creek also received both the most award nominations (21) and wins (8).  No new winners were named for the Academy's annual special awards; instead, the honorees previously named in 2020, most notably Alex Trebek, were celebrated and highlighted.
Taureau (film)
Taureau is a Canadian drama film, directed by Clément Perron and released in 1973. The film centres on the Gilberts, a family in a small town in the Beauce region of Quebec who become a target of social ostracism when their intellectually slow but physically strong and handsome son Taureau (André Melançon) initiates a relationship with Denise (Michèle Magny), the town school teacher.

The film was Perron's first solo-directed narrative fiction feature, following a career principally making documentary films.

The cast also includes Monique Lepage, Béatrice Picard, Marcel Sabourin, Yvon Thiboutot, Amulette Garneau, Louise Portal, André Cartier, Yvan Canuel, Jacques Bilodeau, Marguerite Lemir, Denis Drouin, Anne Létourneau, Marthe Mercure, Edgar Fruitier, Bonfield Marcoux and Pat Gagnon.

Beauce, Quebec
Beauce  (/boʊs/; French pronunciation: [bos] ⓘ) is a historical and traditional region of Quebec, Canada, located south of Quebec City. Most of it is part of the administrative region of Chaudière-Appalaches. It corresponds approximately to the regional county municipalities of Beauce-Sartigan, Beauce-Centre and La Nouvelle-Beauce, and its major communities are Saint-Georges, Sainte-Marie, Beauceville, Saint-Joseph-de-Beauce and Saint-Victor.
Nikolai Belov (ice hockey)
Nikolai Sergeyevich Belov (born August 13, 1987) is a Russian professional ice hockey defenceman who currently plays for IF Björklöven in HockeyAllsvenskan, the second highest league of ice hockey in Sweden. He has previously played in the top Russian leagues with Dynamo Moscow, Neftekhimik Nizhnekamsk, Ak Bars Kazan, SKA Saint Petersburg and Traktor Chelyabinsk.

In the 2014–15 season, Belov was traded by Neftekhimik Nizhnekamsk, along with a first-round pick, to SKA Saint Petersburg in exchange for Evgeny Ryasensky, Alexei Grishin and Mikhail Tikhonov on November 24, 2014.

On February 12, 2021, Belov was bought out from his contract at Almtuna IS by league rival IF Björklöven.

Almtuna IS
Almtuna Idrottssällskap, commonly known as Almtuna IS, is a Swedish ice hockey club based in Uppsala and is currently playing in HockeyAllsvenskan, the second highest league of ice hockey in Sweden. The team maintained its place in the Allsvenskan despite suffering relegation in the 2018–19 season following the exit of IK Pantern due to economic troubles prior to the 2019–20 season.
1977 Tour of the Basque Country
The 1977 Tour of the Basque Country was the 17th edition of the Tour of the Basque Country cycle race and was held from 28 March to 1 April 1977. The race started in Hondarribia and finished in Goiuria. The race was won by José Antonio González Linares of the Kas team.

Hondarribia
Hondarribia (Basque: Hondarribia; Spanish: Fuenterrabía; French: Fontarrabie) is a Spanish town situated on the west shore of the Bidasoa river's estuary, in Gipuzkoa, in the Basque Autonomous Community.

The border town is situated on a little promontory facing Hendaye (France) over the Txingudi bay. A service boat makes the trip between the two. The town has an ancient old quarter with walls and a castle. In addition, Hondarribia features a beach across the Bidasoa from the touristy housing estate Sokoburu in Hendaye, alongside a mountain called Jaizkibel providing a hilly backdrop to the town. A road leads northeast from the beach area to Cape Higuer, located in this municipality.

The town harbours the San Sebastian Airport, which serves domestic flights. The population as of 2005 is 15,700 inhabitants.
TuS Bersenbrück
Turn- und Sportverein Bersenbrück von 1895 e. V. is a German football club based in Bersenbrück, Lower Saxony. Founded in 1895, it plays in the Oberliga Niedersachsen in the fifth tier of the German football league system.

Bersenbrück
Bersenbrück (German pronunciation: [ˈbɛʁzn̩bʁʏk] ⓘ; Low German: Bessenbrügge) is a town in the district of Osnabrück, in Lower Saxony, Germany. It is situated on the river Hase, approx. 30 km north of Osnabrück.
Bersenbrück is the seat of the Samtgemeinde ("collective municipality") Bersenbrück.
Lemminkäinen's Mother
Lemminkäinen's Mother (Lemminkäisen äiti) is an 1897 Romantic nationalist painting by Finnish painter Akseli Gallen-Kallela. The painting illustrates a passage from the Kalevala, the Finnish national epic compiled by Elias Lönnrot in the 19th century.

The painting depicts a scene from a poem where the hero Lemminkäinen has died and his mother has dredged the pieces of her son's lifeless body from the river of Tuonela and sewn them together again. She is shown with the body in pietà style, waiting for the bee, a messenger of the god Ukko (god of the sky, weather, harvest, and thunder), to bring her honey from the gods to bring her son to life again.

Elias Lönnrot
Elias Lönnrot (Finnish: [ˈeliɑs ˈlønruːt] ⓘ; 9 April 1802 – 19 March 1884) was a Finnish polymath, physician, philosopher, poet, musician, linguist, journalist, philologist and collector of traditional Finnish oral poetry. He is best known for synthesizing the Finnish national epic, Kalevala (1835, enlarged 1849) from short ballads and lyric poems he gathered from Finnish oral tradition during several field expeditions in Finland, Russian Karelia, the Kola Peninsula and Baltic countries. In botany, he is remembered as the author of the 1860 Flora Fennica, the first scientific text written in Finnish rather than in Latin.
HMS Reindeer (1804)
HMS Reindeer was an 18-gun Cruizer-class brig-sloop of the Royal Navy, built by Samuel & Daniel Brent at Rotherhithe and was launched in 1804.  She was built of fir, which made for more rapid construction at the expense of durability. Reindeer fought in the Napoleonic Wars before succumbing in 1814 to the guns of USS Wasp during the War of 1812.

Baracoa
Baracoa, whose full original name is Nuestra Señora de la Asunción de Baracoa ('Our Lady of the Assumption of Baracoa'), is a municipality and city in Guantánamo Province near the eastern tip of Cuba. The area was visited by Admiral Christopher Columbus on November 27, 1492, and a settlement founded by the first governor of Cuba, the Spanish conquistador Diego Velázquez de Cuéllar on August 15, 1511. It is the oldest Spanish settlement in Cuba and was its first capital (the basis for its nickname Ciudad Primada, 'First City').
BMW R1100R
The BMW R 1100 R is a standard motorcycle with a 1,085 cc (66.2 cu in) air/oil-cooled flat twin engine, made by BMW Motorrad from 1994 through to 1999. Like all of the brand's motorcycles of this period, all 53,685 units were made at BMW's Spandau, Berlin factory. The R 1100 R was succeeded by the model year 2001 R 1150 R.

The R 1100 R was reviewed favorably by Ulf Böhringer of the Süddeutsche Zeitung. Cycle World was impressed with the 1995 R 1100 R's comfort, versatility, overall quality, and successful combination of a venerable engine and frame layout with the latest technology, while noting the "fussiness" of the idiosyncratic control and accessory operations.

Spandau
Spandau (German: [ˈʃpandaʊ] ⓘ) is the westernmost of the 12 boroughs (Bezirke) of Berlin, situated at the confluence of the Havel and Spree rivers and extending along the western bank of the Havel. It is the smallest borough by population, but the fourth largest by land area.
Lewis and Clark Viaduct
The Lewis and Clark Viaduct  (previously the Intercity Viaduct and historically the Interstate Viaduct; also known as the 6th Street Viaduct or Woodsweather Bridge) are two nine span viaducts that cross the Kansas River in the United States. Designed by Waddell and Hedrick, the first viaduct, a four-lane, deck truss bridge, opened to the public on January 29, 1907, the second bridge, also of the deck truss design, opened to the public on November 12, 1962. It rises above the West Bottoms, and several sets of railroad tracks. The 1907 viaduct is notable for being the first roadway bridge to connect Kansas City, Missouri, with Kansas City, Kansas, non-stop all the way across. It is about 1.5 miles (2.4 km) long and carries Interstate 70/U.S. Route 24/U.S. Route 40/U.S. Route 169 (I-70/US 24/US 40/US 169). The I-670 Viaduct serves as a complementary to the viaduct, it was built in 1990 to the south.

Viaduct
A viaduct is a bridge that consists of a series of arches, piers or columns supporting a long elevated railway or road. Typically a viaduct connects two points of roughly equal elevation, allowing direct overpass across a wide valley, road, river, or other low-lying terrain features and obstacles. The term viaduct is derived from the Latin via meaning "road", and ducere meaning "to lead". It is a 19th-century derivation from an analogy with ancient Roman aqueducts. Like the Roman aqueducts, many early viaducts comprised a series of arches of roughly equal length.
Hossein Ghorbanzadeh
Hossein Ghorbanzadeh (Persian: حسین قربان‌زاده) is an Iranian journalist and Principlist politician who was General Secretary of Progress and Justice Population of Islamic Iran. He is also editor-in-chief of Hamshahri newspaper. He was previously editor-in-chief of local based Tehran Emrooz newspaper.

Iranian principlists
The Principlists (Persian: اصول‌گرایان, romanized: Osul-Garāyān, lit. 'followers of principles or fundamentalists'), also interchangeably known as the Iranian Conservatives and formerly referred to as the Right or Right-wing, are one of two main political camps in post-revolutionary Iran; the Reformists are the other camp. The term hardliners that some Western sources use in the Iranian political context usually refers to the faction. The faction rejects the status quo internationally, but favors domestic preservation.
Nazanin Nour
Nazanin Nour (Persian: نازنین نور, alternatively romanized as Nāzanin Nūr; Persian pronunciation: [nɒːzæˈniːn nuːɾ]) is an Iranian-American actress, model and writer. She has appeared on several television films and shows, including Madam Secretary. She is one of the judges of the first season of Persia's Got Talent, the Persian spin-off of the British talent show Got Talent, produced in Stockholm, Sweden.

Got Talent
Got Talent is a British talent show TV format conceived and owned by Simon Cowell's Syco Entertainment. It has spawned spin-offs in over 60 countries, in what is now referred to as the 'Got Talent' format, similar to that described by Fremantle of the Idol and The X Factor formats. Unlike those shows, Got Talent (influenced by the variety of talent shows Opportunity Knocks and New Faces) showcases other artistic disciplines as well as singers.

In April 2014, the format was named the world's most successful reality TV format ever by Guinness World Records. Cowell said: "I am very proud that Got Talent is a homegrown British show. We owe its success to a group of very talented producers all over the world who have made this happen. And of course amazing talent."
Santiago de Aller CF
Santiago de Aller Club de Fútbol is a Spanish football club based in Morea, Aller, Asturias. Founded in 1952, they play in Tercera Asturfútbol – Group 3, holding home matches at the Campo Federico Mulas.

Morea, Aller
Morea (Spanish name: Moreda, and officially Morea / Moreda) is one of 18 parishes (administrative divisions) in Aller, a municipality within the province and autonomous community of Asturias, in northern Spain.

The altitude 300 m (980 ft) above sea level. It is 27.98 km2 (10.80 sq mi) in size with a population of 3,962 as of January 1, 2024.
1970 United States redistricting cycle
The 1970 United States redistricting cycle took place following the completion of the 1970 United States census. In all fifty states, various bodies re-drew state legislative and congressional districts. States that are apportioned more than one seat in the United States House of Representatives also drew new districts for that legislative body. The resulting new districts were first implemented for the 1972 elections.

Several new laws and judicial decisions throughout the 1960s and the Civil rights movement impacted the 1970-1972 redistricting process, including Wesberry v. Sanders, Reynolds v. Sims, Gomillion v. Lightfoot, Gray v. Sanders, Baker v. Carr, the ratification of the 24th Amendment, and the passage of the Voting Rights Act of 1965 and the Uniform Congressional District Act of 1967.

Uniform Congressional District Act
The Uniform Congressional District Act is a redistricting bill that requires all members of the United States House of Representatives in the 91st United States Congress and every Congress afterwards to be elected from a single-member district unless a state had elected all of its previous representatives at large, for which this requirement commenced for the 92nd United States Congress.
Yohanan Aharoni
Yohanan Aharoni (Hebrew: יוחנן אהרוני; 7 June 1919 – 9 February 1976) was an Israeli archaeologist and historical geographer, chairman of the Department of Near East Studies and chairman of the Institute of Archaeology at Tel Aviv University.

Historical geography
Historical geography is the branch of geography that studies the ways in which geographic phenomena have changed over time. In its modern form, it is a synthesizing discipline which shares both topical and methodological similarities with history, anthropology, ecology, geology, environmental studies, literary studies, and other fields. Although the majority of work in historical geography is considered human geography, the field also encompasses studies of geographic change which are not primarily anthropogenic. Historical geography is often a major component of school and university curricula in geography and social studies. Current research in historical geography is being performed by scholars in more than forty countries.
The Silver Ship and the Sea
The Silver Ship and the Sea is a young-adult science-fiction novel by Brenda Cooper, published in 2007. In 2008, it won the 
Endeavour Award,
and was also one of Booklist's Adult Books for Young Adults Winners.

The Silver Ship and the Sea is the first book in a series.  The other two books are Reading the Wind

and Wings of Creation.  Critical response to The  Silver Ship and the Sea was  generally positive.  Writing in Analog, Richard Foss  criticized the pacing of the next book, "Reading the  Wind".

The book is about six genetically altered children who have been left on the planet Fremont after a war.


They were often mistreated because they descended from the altered who fought against the humans.  These altered were stronger and faster, with better reflexes and sharper senses than the normal humans of Fremont.

Endeavour Award
The Endeavour Award, announced annually at OryCon in Portland, Oregon, is awarded to a distinguished science fiction or fantasy book written by an author or authors from the Pacific Northwest (Oregon, Washington, Idaho, British Columbia, The Yukon, and Alaska) and published in the previous year.

Annual presentation of the Endeavour Award is in November at OryCon for books published during the previous year.
Serial binary adder
The serial binary adder or bit-serial adder is a digital circuit that performs binary addition bit by bit.  The serial full adder has three single-bit inputs for the numbers to be added and the carry in.  There are two single-bit outputs for the sum and carry out.  The carry-in signal is the previously calculated carry-out signal.  The addition is performed by adding each bit, lowest to highest, one per clock cycle.

Circuit (computer science)
In theoretical computer science, a circuit is a model of computation in which input values proceed through a sequence of gates, each of which computes a function. Circuits of this kind provide a generalization of Boolean circuits and a mathematical model for digital logic circuits. Circuits are defined by the gates they contain and the values the gates can produce.  For example, the values in a Boolean circuit are Boolean values, and the circuit includes conjunction, disjunction, and negation gates.  The values in an integer circuit are sets of integers and the gates compute set union, set intersection, and set complement, as well as the arithmetic operations addition and multiplication.
Linus (Mysia)
Linus or Linos (Λῖνος), also Linum or Linon (Λίνον), was a town on the coast of ancient Mysia, on the Propontis, between Priapus and Parium. It is noted by Strabo as the spot where the best snails were found.

Its site is located in Asiatic Turkey.

Karabiga
Karabiga (Karabuga) is a town (belde) in the Biga District, Çanakkale Province, Turkey. Its population is 2,962 (2021). It is located at the mouth of the Biga River, on a small east-facing bay, known as Karabiga Bay.  Its ancient name was Priapus or Priapos (Ancient Greek: Πρίαπος).
Smajlović
Smajlović or Smailović is a Bosnian surname. Notable people with the surname include:

Vedran Smailović (born 1956), Bosnian musician

Ljiljana Smajlović (born 1956), Serbian journalist

Meliha Smajlović (born 1993), Bosnian-Turkish volleyball player

Mišo Smajlović (born 1938), Bosnian football manager and a former player

Vedran Smailović
Vedran Smailović (born 11 November 1956), known as the "Cellist of Sarajevo", is a Bosnian musician. During the siege of Sarajevo, he played Albinoni's Adagio in G minor in ruined buildings, and, often under the threat of snipers, he played during funerals. His bravery inspired musical numbers and the novel The Cellist of Sarajevo by Steven Galloway. He moved to  Northern Ireland and is a composer, conductor, and performer. His playing of the Albinoni Adagio was introduced in a book called "A Story Like the Wind".
Erin Teschuk
Erin Teschuk (born 25 October 1994) is a Canadian middle- and long-distance runner. She represented her country at the 2015 World Championships in Beijing, the 2016 Summer Olympics in Rio, and the 2023 World Championships in Budapest. Collegiately, she competed for the North Dakota State Bison where she was a 15-time Summit League champion and 7-time All-American.

North Dakota State Bison
The North Dakota State Bison are the athletic teams of North Dakota State University (NDSU), which is located in the city of Fargo, North Dakota. The teams are often called the "Thundering Herd". The current logo is a bison.