hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
PSB-10
PSB-10 is a drug which acts as a selective antagonist for the adenosine A3 receptor (ki value at human A3 receptor is 0.44 nM), with high selectivity over the other three adenosine receptor subtypes (ki values at human A1, A2A and A2B receptors are 4.1, 3.3 and 30 μM). Further pharmacological experiments in a [35S]GTPγS binding assay using hA3-CHO-cells indicated that PSB-10 acts as an inverse agonist (IC50 = 4 nM). It has been shown to produce antiinflammatory effects in animal studies. Simple xanthine derivatives such as caffeine and DPCPX have generally low affinity for the A3 subtype and must be extended by expanding the ring system and adding an aromatic group to give high A3 affinity and selectivity. The affinity towards adenosine A3 subtype was measured against the radioligand PSB-11.

Anti-inflammatory
Anti-inflammatory refers to any drug, substance or mechanism that reduces inflammation by lessening the redness, swelling, fever, or pain and loss of function which are part of bodies inflammatory response. Anti-inflammatory drugs are agents that inhibit action or production of inflammatory mediators such as cytokines, histamines and prostaglandins. These drugs reduce pain by inhibiting mechanisms of inflammation, as opposed to opioids, which affect the central nervous system to block pain.

Common anti-inflammatory drugs include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, antileukotrienes, and monoclonal antibodies.
Shanthalli
Shanthalli  is a village in Somwarpet taluk in Kodagu district of Karnataka, India.

It lies on SH-8. Shanthalli is located 11 km from taluk headquarter Somvarpete, 45 km from district headquarter Madikeri and 260 km from the state capital Bengaluru.

The village is famous for its annual fair of local deity, Lord Kumara Lingeshwara. Nearby tourist places are Mallalli Falls and Kumara Parvata hill located at 11 km and 14 km respectively.

Mallalli Falls
Mallalli Falls is situated in the Somwarpet Coorg District in Karnataka state in south India. The Kumaradhara River is the main watercourse for this waterfall. The Kumaradhara later flows through Kukke Subrahmanya and merges with the Netravati River at Uppinangadi, which then empties into the Arabian Sea at Mangalore.
Traders season 1
This is a list of episodes for Traders, a Canadian television drama series, which was broadcast on Global Television Network from 1996 to 2000.  The show was set in a Bay Street investment bank, Gardner Ross. Bruce Gray and Sonja Smits starred as the firm's senior partners, Adam Cunningham and Sally Ross. The cast also included Patrick McKenna, Janet Bailey, David Cubitt, Rick Roberts, Kim Huffman, Chris Leavins, Gabriel Hogan, David Hewlett, Peter Stebbings and Alex Carter.

Chris Leavins
Chris Leavins is a Canadian actor and writer based in Los Angeles. Known for playing Atticus Murphy, Jr. the malevolent school guidance counselor on cult TV series Todd and the Book of Pure Evil. He has appeared in a number of successful Canadian television shows, been nominated for two Gemini Awards and shared in a Gemini Award for Ensemble Performance win. He also created and hosted satirical internet show, Cute With Chris.
Jamie Richards (cyclist)
James Blake "Jamie" Richards (born 2 March 1957) is a cyclist from New Zealand.

Richards was born in Pukekohe, Auckland, in 1957. Mike Richards is his younger brother.

Richards competed in the individual road race event at the 1976 Summer Olympics; he did not finish the race.

Cycling at the 1976 Summer Olympics – Men's individual road race
The men's individual road race at the 1976 Summer Olympics in Montreal, Quebec, Canada, was held on 26 July 1976. There were 134 cyclists from 40 nations starting the race. The maximum number of cyclists per nation was four. Fifty-eight cyclists finished the race. The event was won by Bernt Johansson of Sweden, the nation's first victory in the men's individual road race. Giuseppe Martinelli put Italy back on the podium with his silver; the nation had won gold or silver at every Games from 1956 to 1968 but did not medal in 1972. Mieczysław Nowicki's bronze was Poland's first medal in the event.
Reece Caira
Reece Caira is an Australian semi-professional footballer who plays as a left back for Berkeley Vale in the Premier League Central Coast, a regional league within the Australian soccer league system. Caira has previously played professionally as a youth player for Aston Villa and as a senior for Western Sydney Wanderers, Wellington Phoenix and Bonnyrigg White Eagles. In 2017 he played for Valentine Phoenix as a short-term signing to boost their bid for the NSW Finals. Caira has represented Australia at a number of youth levels and was part of the 2012 AFC U-19 Championship squad that reached the semi-finals of that tournament.

Valentine FC
Valentine FC is a semi-professional football club based in Valentine in the Hunter Region, New South Wales and is part of the Valentine Eleebana Football Club. Valentine have been promoted to the National Premier Leagues Northern NSW for 2016 with teams in First Grade, Under 23s, Under 19 and Under 17 divisions.

Notable former players include Adam Griffiths, Giancarlo Gallifuoco and Daniel Bowles.
Pinware
Pinware is a town in the Canadian province of Newfoundland and Labrador. The town has a population of 64, according to the Canada 2021 Census.

The town is located along Route 510 in Labrador, between L'Anse-au-Diable and Red Bay.

The community has been formerly known as Riviere des François, Pirouette River, and Black Bay. It is believed the name is a corruption of Pied Noir (black foot) from the shape of a rock found at the mouth of Black Rock Brook.

Labrador
Labrador (/ˈlæbrədɔːr/) is a geographic and cultural region within the Canadian province of Newfoundland and Labrador.  It is the primarily continental portion of the province and constitutes 71% of the province's area but is home to only 6% of its population. It is separated from the island of Newfoundland by the Strait of Belle Isle. It is the largest and northernmost geographical region in the four Atlantic provinces.

Labrador occupies most of the eastern part of the Labrador Peninsula. It is bordered to the west and south by the province of Quebec. Labrador also shares a small land border with the territory of Nunavut on Killiniq Island.

The indigenous peoples of Labrador include the Northern Inuit of Nunatsiavut, the Southern-Inuit of NunatuKavut, and the Innu of Nitassinan.
Kodangal Assembly constituency
Kodangal Assembly constituency is a constituency partially in Vikarabad district and Mahabubnagar district of Telangana  that elects representatives to the Telangana Legislative Assembly in India. It is one of the seven assembly segments of Mahabubnagar Lok Sabha constituency.

Anumula Revanth Reddy is the current MLA from the constituency and has been serving as the second Chief Minister of Telangana since winning the 2023 Telangana Legislative Assembly election as a candidate of the Indian National Congress.

2023 Telangana Legislative Assembly election
The 2023 Telangana Legislative Assembly election was held on 30 November 2023 to elect all 119 members of Telangana Legislative Assembly for its third term. The votes were counted and the results were declared on 3 December 2023.

The Indian National Congress (INC) along with its ally Communist Party of India (CPI) won a majority with 65 seats against the incumbent Bharat Rashtra Samithi (BRS)'s 39 seats. With a victory for the first time after the formation of Telangana, it strengthened its position in southern India following its recent success in Karnataka. The BRS and then-CM K. Chandrashekar Rao suffered a major loss in the elections by losing in one of his contended seats after being in power for two terms.
Fallout season 2
The second season of the American post-apocalyptic drama television series Fallout premiered on December 16, 2025 on Amazon Prime Video, with the remaining episodes released weekly through February 3, 2026. Based on the role-playing video game franchise created by Tim Cain and Leonard Boyarsky, the series is set two centuries after the Great War of 2077, in which society has collapsed following a nuclear holocaust.

The season stars Ella Purnell, Aaron Moten, Moisés Arias, Frances Turner, Kyle MacLachlan, and Walton Goggins. This season continues the story set in the wasteland of post-nuclear America and introduced New Vegas, a major location from the video game Fallout: New Vegas. In May 2025, Amazon renewed the series for a third season.

Leslie Uggams
Leslie Marian Uggams (/ˈʌɡəmz/; born May 25, 1943) is an American actress and singer. After beginning her career as a child in the early 1950s, she garnered acclaim for her role in the Broadway musical Hallelujah, Baby!, winning a Theatre World Award in 1967 and the Tony Award for Best Actress in a Musical in 1968. Uggams gained wider recognition for portraying Kizzy Reynolds in the television miniseries Roots (1977), earning Golden Globe and Emmy Award nominations for her performance.

Later in her career, Uggams received renewed notice with appearances as Blind Al in the superhero films Deadpool (2016), Deadpool 2 (2018), and Deadpool & Wolverine (2024). Her other prominent roles were as Leah Walker on the Fox musical drama series Empire (2016–2020); as Agnes Ellison in the comedy-drama film American Fiction (2023); and as Betty Pearson in the Amazon Original post-apocalyptic drama series Fallout (2024–present), based on the video game of the same name.
Spotlight 29 Casino
Spotlight 29 Casino is an Indian casino in Coachella, California, owned and operated by the Twenty-Nine Palms Band of Mission Indians of California. The casino is 250,000 square feet, with 1,600 slot machines and 22 table games. Amenities include two restaurants, food court, three bars and the Spotlight Showroom, which seats 2,200.

Casino game
A casino game is one in which players gamble cash or chips on various possible random outcomes or combinations of outcomes, often in a casino environment. Such games are also available in online casinos, where permitted by law. Casino games can also be played outside of casinos for entertainment purposes, like in parties or in school competitions, on machines that simulate gambling.
Tikchik River
The Tikchik River is a  45 miles (72 km) long stream in the U.S. state of Alaska. Beginning at Nishlik Lake in the Kuskokwim Mountains, it flows southeast into Tikchik Lake, 65 miles (105 km) north of Dillingham. Tikchik Lake empties into the Nuyakuk River, a tributary of the Nushagak River, which flows to Nushagak Bay, an arm of Bristol Bay.

Water from Upnuk Lake flows about 10 miles (16 km) to join the river downstream of Nishlik Lake. Both lakes and the river lie within Wood-Tikchik State Park, at 1.6 million acres (6,500 km2) the largest state park in the United States.

Alaska Fishing says the river "makes an exciting float...with some potentially good fishing...".  Boating dangers include overhanging vegetation and bears, which feed on salmon. The main game fish frequenting the Tikchik are Arctic grayling, char, and red salmon, as well as lake trout in the lakes.

Dillingham, Alaska
Dillingham /ˈdɪlɪŋhæm/ (Central Yupik: Curyung), also known as Curyung, is a city in Dillingham Census Area, Alaska, United States. Incorporated in 1963, it is an important commercial fishing port on Nushagak Bay. As per the 2020 census, the population of the city was 2,249, down from 2,329 in 2010.
Fugate
Fugate is a surname. Notable people with the surname include:

the "Blue Fugates," a Kentucky family with a hereditary blood disorder that caused many family members to have blue skin

Boyd C. Fugate (1884–1967), American politician

Caril Ann Fugate (born 1943), American murderer

Christine Fugate (born 1964), American documentary filmmaker

Craig Fugate (born 1959), American government official

Joe Fugate, American writer and game designer

Katherine Fugate (born 1965), American film and television writer

Terry Fugate-Wilcox (born 1944), American artist born Raymond Terry Fugate

Thomas B. Fugate (1899–1980), American businessman

Christine Fugate
Christine Fugate is an American film producer and director who has filmed across the globe, making projects in Thailand, Malawi, Australia and Great Britain.

Fugate is known for her documentaries and independent films. She is also a journalist, interviewer, and author of Mothering Heights, a column which was published in the Laguna Beach Independent. In 2008, she edited a collection of essays by women sharing diverse perspectives on the same subject, The Mothering Heights Manual for Motherhood, Volume I. She also writes short stories which have appeared in several short story collections including in "Beach Reads: Adrift" and "Beach Reads: Paradise".
Dolly Nazir
Dolly Rustom Nazir nee Byramji (1935–2012) was an Indian swimmer. She competed in two events at the 1952 Summer Olympics.

Nazir won Long Distance Open Sea Championships in Bombay in 1948 at the age of 13 and repeated the win the next year. In November 1950, she bettered the national record for 100  meters backstroke by more than three seconds while winning the All India Swimming Championships.

She married horse breeder and trainer Rashid Byramji in 1965 and moved to Bangalore.

Swimming at the 1952 Summer Olympics
At the 1952 Summer Olympics in Helsinki, a total number of eleven swimming events were contested, six for men and five for women. The events were held at the Swimming Stadium.  There was a total of 319 participants from 48 countries competing.
All the Best, Isaac Hayes
All the Best, Isaac Hayes is a studio album by the American singer and songwriter Mark Kozelek, released on April 24, 2020 on Caldo Verde Records. Recorded between October and November 2019, it is Kozelek's thirty-first studio album.

The album features spoken word, stream of consciousness compositions with piano accompaniment throughout. Its lyrical content focuses on Kozelek's experiences during a 2019 North American tour and its aftermath.

Caldo Verde Records
Caldo Verde Records is a San Francisco–based indie rock and folk record label founded by Red House Painters and Sun Kil Moon frontman Mark Kozelek in 2005. The label primarily features releases by Kozelek and Sun Kil Moon, but has also released albums by Jesu, Corrina Repp, Retribution Gospel Choir, and Kath Bloom. Photographer Nyree Watts is the commissioned artist for Caldo Verde, as almost all of the releases on the label feature her photography.
New Hampshire Troubadour
The New Hampshire Troubadour was a monthly magazine supported by the State Planning and Development Commission of New Hampshire and which was originally published from 1931 to 1951. It was subsequently published under several private owners and titles, most prominently as New Hampshire Profiles.

It was briefly revived under the original name for a few years early in the twenty-first century, as a quarterly magazine published by a 501(c)(3) charitable organization with no paid employees.

The magazine's first editor was Thomas Dreier.

During the Troubadour's original run three covers were illustrated by American artist Maxfield Parrish.

Maxfield Parrish
Maxfield Parrish (July 25, 1870 – March 30, 1966) was an American painter and illustrator active in the first half of the 20th century. His works featured distinctive saturated hues and idealized neo-classical imagery. The National Museum of American Illustration deemed his painting Daybreak (1922) to be the most successful art print of the 20th century.
Jitendra Singh (Uttar Pradesh politician)
Jitendra Singh is a politician from the Bahujan Samaj Party and currently named as the vice president of UP Handball Association. In 2007 he was elected as Member of Legislative Assembly representing Bikapur constituency in Faizabad District in the state legislature of Uttar Pradesh. He was a renowned basketball player.

He was arrested along with Intezar Abidi for attacking and setting fire to the house of State Congress leader Rita Bahuguna in central Lucknow. He is often referred to with epithets such as 'Bahubali', 'Don' or the 'Don of Eastern Uttar Pradesh'. He has been known for the good works in his constituency. A nickname has also been given to him by the people 'Bablu Bhaiya'. His brother Guddu Singh is also MLC from the same party.

Ayodhya district
Ayodhya district (formerly Faizabad district) is one of the 75 districts in the northern Indian state of Uttar Pradesh. The city of Ayodhya is its administrative headquarters. The district occupies an area of 2,522 square kilometres (974 sq mi), and had a population of 2,470,996 in the 2011 census. Ayodhya district shares its borders with 6 districts of Uttar Pradesh. It is bordered by Gonda and Basti districts on the northern side, Amethi and Sultanpur districts on the south, and Ambedkar Nagar and Barabanki districts share the border on the east and west.

The official name of the district was changed from Faizabad to Ayodhya in November 2018.
Prohibition
Prohibition is the act or practice of forbidding something by law; more particularly the term refers to the banning of the manufacture, storage (whether in barrels or in bottles), transportation, sale, possession, and consumption of alcoholic beverages. The word is also used to refer to a period of time during which such bans are enforced.

Bottle
A bottle is a narrow-necked container made of an impermeable material (such as glass, pottery, porcelain, plastic or aluminium) in various shapes and sizes that stores and transports liquids. Its mouth, at the bottling line, can be sealed with an internal stopper, an external bottle cap, a closure, or induction sealing.
IMPAR
IMPAR is a leading insurance company of Cape Verde. Its headquarters are on Avenida Amílcar Cabral in Praia. It has 11 offices in the islands of Santiago, São Vicente, São Nicolau, Santo Antão, Sal, Boa Vista and Fogo. It was established in January 1992 as the first private insurance company of Cape Verde.

IMPAR Group consists of Seguradora IMPAR and Banco Caboverdiano de Negócios.

São Nicolau, Cape Verde
São Nicolau (Portuguese for Saint Nicholas) is one of the Barlavento (Windward) islands of Cape Verde. It is located between the islands of Santa Luzia and Sal. Its population is 12,424 (2015),: 36  with an area of 343 km2 (132 sq mi).: 25  The main towns are Ribeira Brava and Tarrafal de São Nicolau.
Sadovy, Voronezh Oblast
Sadovy (Russian: Садовый) is a rural locality (a settlement) in Timiryazevskoye Rural Settlement, Novousmansky District, Voronezh Oblast, Russia. The population was 205 as of 2010. There are three streets.

Novousmansky District
Novousmansky District (Russian: Новоу́сманский райо́н) is an administrative and municipal district (raion), one of the thirty-two in Voronezh Oblast, Russia. It is located in the north of the oblast. The area of the district is 1,247 square kilometers (481 sq mi). Its administrative center is the rural locality (a selo) of Novaya Usman. Population: 786,930 (2021 Census); 73,034 (2010 Census); 64,275 (2002 Census); 64,182 (1989 Soviet census). The population of Novaya Usman accounts for 42.0% of the district's total population.
DUSP2
Dual specificity protein phosphatase 2 is an enzyme that in humans is encoded by the DUSP2 gene.

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily.  These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.  They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation.

Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.  This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.

Kinase
In biochemistry, a kinase (/ˈkaɪneɪs, ˈkɪneɪs, -eɪz/) is an enzyme that catalyzes the transfer of phosphate groups to substrates. This process is known as phosphorylation.  Typically ATP is the phosphate donor. Kinases are pervasive, the human genome codes for about 500 of these enzymes.

Kinases are part of the larger family of phosphotransferases. Kinases should not be confused with phosphorylases, which catalyze the addition of inorganic phosphate groups to an acceptor, nor with phosphatases, which remove phosphate groups (dephosphorylation). The phosphorylation state of a molecule, whether it be a protein, lipid or carbohydrate, can affect its activity, reactivity and its ability to bind other molecules. Therefore, kinases are critical in metabolism, cell signalling, protein regulation, cellular transport, secretory processes and many other cellular pathways, which makes them very important to physiology.
Vishakha N. Desai
Vishakha N. Desai is an Asia scholar with a focus on art, culture, policy, and women's rights. She currently serves as senior advisor for global affairs to the president of Columbia University, senior research scholar in Global Studies at its School of International and Public Affairs and chair of the Committee on Global Thought at Columbia University. She was president emerita of the Asia Society (2004–2012). In recognition of her leadership in the museum field, President Barack Obama appointed her to serve on the National Commission on Museums and Libraries in 2012. Desai has been recognized as one of the "Most Powerful Women in New York" by Crains Magazine, and for her Distinguished Service to the Visual Arts by ArtTable. She is a recipient of five honorary degrees from Centre College, Pace University, the College of Staten Island, Susquehanna University, and Williams College.

Susquehanna University
Susquehanna University is a private liberal arts college in Selinsgrove, Pennsylvania, United States. Its name is derived from the original Susquehannock settlers of the region. Founded in 1858 as a missionary institute, it became a four-year liberal arts college in 1895. It is affiliated with the Evangelical Lutheran Church in America. In addition to an arts and sciences focus, Susquehanna has a business school, master's degrees in education, and joint-degree programs in engineering and for a Master of Business Administration.

The academic programs are within the four schools of the arts, humanities, natural and social sciences, and the AACSB International-accredited Sigmund Weis School of Business. Susquehanna University enrolls more than 2,200 undergraduate students from 33 states and 23 countries, and maintains a student-to-faculty ratio of 12 to 1.
Hole Rock
Hole Rock (61°53′S 57°44′W﻿ / ﻿61.883°S 57.733°W﻿ / -61.883; -57.733) is the largest of several rocks lying close north of North Foreland, the northeast cape of King George Island, in the South Shetland Islands. It was charted in 1937 by Discovery Investigations personnel on the Discovery II and so named because a conspicuous hole extends through it.

King George Island (South Shetland Islands)
King George Island (Argentinian Spanish: Isla 25 de Mayo, Brazilian Portuguese: Ilha do Rei George, Chilean Spanish: Isla Rey Jorge, Russian: Ватерло́о Vaterloo) is the largest of the South Shetland Islands, lying 120 km (75 miles) off the coast of Antarctica in the Southern Ocean.  The island was named after King George III.