hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
1-Keto-1,2,3,4-tetrahydrophenanthrene
1-Keto-1,2,3,4-tetrahydrophenanthrene (THP-1), or 1,2,3,4-tetrahydrophenanthren-1-one, is a synthetic steroid-like compound which was reported to be the first xenoestrogen. It was first synthesized in 1933 by Cook et al. and was tested due to its similarity to the presumed chemical structure of estrone. Upon reassessment many decades later, the compound was found to bind only weakly to the estrogen receptors, and, unexpectedly, did not actually have functional activity as an estrogen or antiestrogen in vitro or in vivo. It did, however, show some mixed androgenic and antiandrogenic activity in vitro.

Intrinsic activity
Intrinsic activity (IA) and maximal efficacy (Emax) refer to the relative ability of a drug-receptor complex to produce a maximum functional response. This must be distinguished from the affinity, which is a measure of the ability of the drug to bind to its molecular target, and the EC50, which is a measure of the potency of the drug and which is proportional to both efficacy and affinity. This use of the word "efficacy" was introduced by Stephenson (1956) to describe the way in which agonists vary in the response they produce, even when they occupy the same number of receptors. High efficacy agonists can produce the maximal response of the receptor system while occupying a relatively low proportion of the receptors in that system. There is a distinction between efficacy and intrinsic activity.
1995 WAFU Club Championship
The 1995 WAFU Club Championship was the 18th  football club tournament season that took place for the runners-up or third place of each West African country's domestic league, the West African Club Championship. It was won again by Nigeria's Bendel Insurance after defeating Plateau United in two legs, it was the first final that feature both clubs from a single country.  A total of about around 35 goals were scored.

Plateau United F.C.
Plateau United Football Club of Jos (usually known as Plateau United) is a Nigerian professional football (soccer) club based in Jos, that competes in the Nigerian Professional Football League. Before 1991, they were known as the JIB Strikers FC. The name "Plateau United" was the former name of their cross-town rivals Mighty Jets.
Mini-puberty
Mini-puberty is a transient hormonal activation of the hypothalamic-pituitary-gonadal (HPG) axis that occurs in infants shortly after birth. This period is characterized by a surge in the secretion of gonadotropins (LH and FSH) and sex steroids (testosterone in males and estradiol in females), similar to but less intense than the hormonal changes that occur in puberty during adolescence. Mini-puberty plays a crucial role in the early development of the reproductive system and the establishment of secondary sexual characteristics.

Development of the reproductive system
The development of the reproductive system is the part of embryonic growth that results in the sex organs and contributes to sexual differentiation. Due to its large overlap with development of the urinary system, the two systems are typically described together as the genitourinary system.

The reproductive organs develop from the intermediate mesoderm and are preceded by more primitive structures that are superseded before birth. These embryonic structures are the mesonephric ducts (also known as Wolffian ducts) and the paramesonephric ducts, (also known as Müllerian ducts). The mesonephric duct gives rise to the male seminal vesicles, epididymides and vasa deferentia. The paramesonephric duct gives rise to the female fallopian tubes, uterus, cervix, and upper part of the vagina.
Jaguar I-Pace eTrophy
The Jaguar I-Pace eTrophy was a battery electric zero-emission international motor racing series supporting the FIA Formula E Championship which ran two seasons from late 2018 to mid 2020. The series was cancelled after the 2019–20 season, due to the COVID-19 pandemic.
The eTrophy saw entrants compete in a race-prepared Jaguar I-Pace, also bearing the same name as the series,  with the races taking place on selected Formula E weekends.

2019–20 Formula E Championship
The 2019–20 FIA Formula E Championship was the sixth season of the FIA Formula E championship, a motor racing championship for electrically powered vehicles recognised by motorsport's governing body, the Fédération Internationale de l'Automobile (FIA), as the highest class of competition for electric open-wheel racing cars.

On 13 March, Formula E and the FIA announced a temporary suspension of the season in response to the COVID-19 pandemic. During the suspension, Formula E organised an esports racing series called Formula E Race at Home Challenge. The season resumed and concluded in August with six races within nine days at the Tempelhof Airport Street Circuit.

The season's champion was António Félix da Costa who clinched his first title with two races left. DS Techeetah became team champions for the second time in a row.
Priority Development Assistance Fund
The Priority Development Assistance Fund (PDAF) was a discretionary fund in the Philippines available to members of Congress. Originally established as the Countrywide Development Fund (CDF) in 1990, it was designed to allow legislators to fund small-scale infrastructure or community projects which fell outside the scope of the national infrastructure program, which was often restricted to large infrastructure items.

The PDAF was commonly called the "pork barrel", and was the subject of much public criticism following exposés on abuses perpetuated by members of Congress on use of the fund in 1996 and 2013.

On November 19, 2013, the Supreme Court declared the PDAF unconstitutional, thereby abolishing it.

Pork barrel
Pork barrel, or simply pork, is a metaphor for allocating government spending to localized projects in the representative's district or for securing direct expenditures primarily serving the sole interests of the representative. The usage originated in American English, and it indicates a negotiated way of political particularism.
Stob na Cruaiche
Stob na Cruaiche (739 m) is a hill in the Grampian Mountains, Scotland. It lies on the border of Highland and Perthshire, on the northern edge of Rannoch Moor.

A very isolated peak, it takes the form of a long ridge that encloses much of the northern side of Rannoch Moor. It can be reached either from Rannoch station or from Black Corries Lodge to the west.

Rannoch railway station
Rannoch railway station, on the West Highland Line, serves the area of Rannoch in Perth and Kinross, Scotland. In 2017, Simon Jenkins reported it to be one of the best 10 stations in Britain. It is situated between Corrour and Bridge of Orchy, 64 miles 36 chains (103.7 km) from Craigendoran Junction, near Helensburgh. ScotRail manage the station and operate most services, along with Caledonian Sleeper.
Joseph Bromfield
Joseph Bromfield (1744–1824) was a notable English plasterer and architect working in the West Midlands and in Central and Northern Wales in the late Georgian period. He was Mayor of Shrewsbury in 1809.

Rhug
Rhug (normally Y Rug in Welsh; sometimes given the antiquarian spelling Rûg) is a township in the parish of Corwen, Denbighshire, Wales, formerly in the old cantref of Edeirnion and later a part of Merionethshire, two miles from Corwen and ten miles north east of Bala. It includes the hamlet of Bonwen. It is situated near the River Dee, under Berwyn range. About 1150, it was ruled by the Maer Du or "Black Mayor of Rhug" and later became part of the lands of the barons of Edeirnion (see Hughes of Gwerclas) who ruled from Gwerclas Castle.
German submarine U-480
German submarine U-480 was an experimental Kriegsmarine Type VIIC U-boat of World War II.

Considered by many to be the first stealth submarine, it was equipped with a special rubber skin of anechoic tiles (codenamed Alberich, after the German mythological character who had the ability to become invisible), that made it difficult to detect with the Allies' ASDIC (sonar). She was one of about six Type VIIs so equipped.

The U-boat was laid down in the Deutsche Werke in Kiel as yard number 311 on 8 December 1942, launched on 14 August 1943 and commissioned on 6 October 1943 under Oberleutnant zur See Hans-Joachim Förster. U-480 carried out three war patrols, all under Förster's command. Because of its coating, the boat was sent to the heavily defended English Channel.

Deutsche Werke
Deutsche Werke Kiel AG was a German shipbuilding company that was founded in 1925 when Kaiserliche Werft Kiel and other shipyards were merged. It came as a result of the Treaty of Versailles after World War I that forced the German defense industry to shrink. The company was owned by the government of the Weimar Republic and its headquarters was in Berlin while the manufacturing location was in Kiel.
Johnny McElhone
John Francis McElhone (born 21 April 1963) is a Scottish guitarist and songwriter from Glasgow.

He played with three bands who have enjoyed a top-20 presence on the UK Singles Chart; the new wave bands Altered Images and Hipsway, and the alternative/pop rock band Texas. Both Altered Images and Texas have had top 20 albums on the UK Albums Chart.

He is one of four children of Scottish Labour MPs Frank and Helen McElhone. He is the father of child actor Jack McElhone, who co-starred with Gerard Butler and Emily Mortimer in the 2004 film Dear Frankie.

Jack McElhone
Jack McElhone (born 1994) is a Scottish former actor. He is famous for his role as Frankie in the 2004 film Dear Frankie, for which he was nominated for a BAFTA Scotland Award. He also had roles in Young Adam, The Book Group, Stacked and Nowhere Boy.
2014 Georgia gubernatorial election
The 2014 Georgia gubernatorial election took place on November 4, 2014, to elect the governor of Georgia, concurrently with the election to Georgia's Class II U.S. Senate seat, as well as other elections to the United States Senate in other states and elections to the United States House of Representatives and various state and local elections.

Incumbent Republican Governor Nathan Deal was elected to a second term in office by a margin of 7.8%. He defeated two primary challengers and in the general election, defeated Democratic state senator Jason Carter and Libertarian nominee businessman and engineer Andrew Hunt, who were unopposed in their respective primaries. As of 2022, this is the last time that Cobb and Gwinnett counties voted for the Republican candidate for governor; and the last time that Burke, Chattahoochee, Dooly, Quitman, Twiggs, Washington, and Wilkinson counties voted for the Democratic candidate.

Wilkinson County, Georgia
Wilkinson County is a county located in the central portion of the U.S. state of Georgia. As of the 2020 census, the population was 8,877. The county seat is Irwinton. The county was created on May 11, 1803, and named for General James Wilkinson (1757–1825).
The Beginning of a Novel
The Beginning of a Novel (Počátek Románu) is an opera by Leoš Janáček to a Czech libretto by Jaroslav Tichý after a short story by Gabriela Preissová, itself suggested by a painting by Jaroslav Věšín. Composed in 1891, it was first produced on 2 October 1894 in Brno.

Although not a successful work, it is significant because it marks the beginning of Janáček's association with Gabriela Preissová, who also wrote the story on which Jenůfa, his first great opera, was based. Originally planned as a singspiel with spoken dialogue, The Beginning of a Novel is unusual among Janáček's stage works in being a "numbers opera" rather than composed with continuous music.

Jaroslav Věšín
Jaroslav František Julius Věšín (Bulgarian: Ярослав Франтишек Юлиус Вешин, romanized: Yaroslav Frantishek Yulius Veshin; 23 May 1860 – 9 May 1915) was a Czech painter who mainly worked in Bulgaria and who was noted as a master of genre painting. The realistic depiction of battle scenes from the First Balkan War (1912) are the subject of a substantial part of his work.
1953 Circuit du Lac
The 5th Circuit du Lac was a Formula Two motor race held on 26 July 1953 at the Aix-les-Bains Circuit du Lac, France. The race was run over two heats each of 50 laps, with the winner being decided by aggregate time. The winner was Élie Bayol in an O.S.C.A. Tipo 20, finishing second and first in the two heats. Louis Rosier was second in a Ferrari 500 and Lance Macklin third in a HWM-Alta. Gordini driver Jean Behra won the first heat and set fastest overall lap during heat 2, and his teammate Harry Schell set pole position and fastest lap for heat 1, but both retired with mechanical problems.

Alta Car and Engineering Company
The Alta Car and Engineering Company was a British sports and racing car manufacturer, commonly known simply as Alta. Their cars contested five FIA World Championship races between 1950 and 1952, as well as Grand Prix events prior to this. They also supplied engines to a small number of other constructors, most notably the Connaught and HWM teams.
Ronald C. Kennedy
Ronald C. Kennedy (December 3, 1954 – June 29, 2011) was a virus immunologist at Texas Tech University. Prior to his appointment there he was affiliated with Baylor University, where he had previously done postdoctoral studies. Furthermore, when he switched affiliations to Texas Tech, he was also an adjunct, associate and full professor in the Departments of Microbiology and Pediatrics at the University of Texas Health Science Center at San Antonio. After his tenure in San Antonio, he switched affiliations to the University of Oklahoma Health Sciences Center's department of microbiology and immunology. In the 1980s he was affiliated with the Southwest Foundation for Biomedical Research, during which time he published some research pertaining to SV40 and intracellular protein transport. More recently, Kennedy has published some research regarding DNA vaccination, mostly in the journal Cancer Immunology, Immunotherapy.

DNA vaccine
A DNA vaccine is a type of vaccine that transfects a specific antigen-coding DNA sequence into the cells of an organism as a mechanism to induce an immune response.

DNA vaccines work by injecting genetically engineered plasmid containing the DNA sequence encoding the antigen(s) against which an immune response is sought, so the cells directly produce the antigen, thus causing a protective immunological response.  DNA vaccines have theoretical advantages over conventional vaccines, including the "ability to induce a wider range of types of immune response".  Several DNA vaccines have been tested for veterinary use. In some cases, protection from disease in animals has been obtained, in others not.  Research is ongoing over the approach for viral, bacterial and parasitic diseases in humans, as well as for cancers. In August 2021, Indian authorities gave emergency approval to ZyCoV-D. Developed by Cadila Healthcare, it is the first DNA vaccine approved for humans.
Lunar observation
The Moon is the largest natural satellite of and the closest major astronomical object to Earth. The Moon may be observed by using a variety of optical instruments, ranging from the naked eye to large telescopes. The Moon is the only celestial body upon which surface features can be discerned with the unaided eyes of most people.

Telescope
A telescope is a device used to observe distant objects by their emission, absorption, or reflection of electromagnetic radiation. Originally, it was an optical instrument using lenses, curved mirrors, or a combination of both to observe distant objects – an optical telescope. Nowadays, the word "telescope" is defined as a wide range of instruments capable of detecting different regions of the electromagnetic spectrum, and in some cases other types of detectors.

The first known practical telescopes were refracting telescopes with glass lenses and were invented in the Netherlands at the beginning of the 17th century. They were used for both terrestrial applications and astronomy.

The reflecting telescope, which uses mirrors to collect and focus light, was invented within a few decades of the first refracting telescope.

In the 20th century, many new types of telescopes were invented, including radio telescopes in the 1930s and infrared telescopes in the 1960s.
Exmortus
Exmortus is an American thrash metal band formed in Whittier, California in 2002. The group has incorporated elements of progressive, death and neo-classical metal into its sound, and their lyrics mostly deal with battles and war.

Whittier, California
Whittier (/ˈhwɪtiər/) is a city in Los Angeles County, California, United States. Part of the Gateway Cities, the 14.7-square-mile (38.0 km2) city had 87,306 residents as of the 2020 United States census. Whittier was incorporated in February 1898 and became a charter city in 1955. The city is named for the Quaker poet John Greenleaf Whittier and is home to Whittier College. The city is surrounded by four unincorporated areas sharing the Whittier name, West Whittier-Los Nietos, North Whittier, South Whittier, and East Whittier, which combined are home to a larger population than Whittier proper.
Ramesh Nimantha
Ramesh Nimantha (born 25 April 1997) is a Sri Lankan cricketer. He made his first-class debut for Sri Lanka Ports Authority Cricket Club in the 2017–18 Premier League Tournament on 28 December 2017. Prior to his first-class debut, he scored 1,000 runs in the U19 Division One League tournament in 2016, and became the leading run-scorer in the competition.

He made his List A debut for Sri Lanka Ports Authority Cricket Club in the 2017–18 Premier Limited Overs Tournament on 10 March 2018. He made his Twenty20 debut on 22 May 2022, for Bloomfield Cricket and Athletic Club in the Major Clubs T20 Tournament.

Bloomfield Cricket and Athletic Club
Bloomfield Cricket and Athletic Club is a first-class cricket team based in Colombo, Sri Lanka. It is one of Sri Lanka's oldest cricket clubs founded in 1892 and competes in the Premier Trophy, which it has won eight times. Its ground, the Bloomfield Cricket and Athletic Club Ground, is in the Cinnamon Gardens district of Colombo, on Reid Avenue, opposite Royal College.
Ray MacDonald
Ray MacDonald (Thai: เรย์ แมคโดนัลด์; born May 21, 1977) is a Thai actor, adventurer, television presenter and host. He won Best Actor awards at the Thailand National Film Association Awards in 1997 and 1998 for his roles in Fun Bar Karaoke, the debut feature by Pen-Ek Ratanaruang, and O-Negative, which co-starred Tata Young. MacDonald has also been featured in Fake and the Pang Brothers' The Eye 10.

He portrayed Dark Ultraman in the PROJECT ULTRAMAN television series.

In 2007, he co-starred in the supernatural thriller, Opapatika.

Tata Young
Amita Marie "Tata" Young (Thai: อมิตา มารี "ทาทา" ยัง; born 14 December 1980) is a Thai singer, actress and model who gained prominence in Thailand when she placed first in a national singing contest at age 11, subsequently signing a record deal and releasing her first album Amita Tata Young in 1995. Young has released eight studio albums, three in English and five in Thai. Her most recent album is Ready for Love, released in 2009.

She has acted in three films, The Red Bike Story (Jakkayan See Daeng), O-Negative and Plai Tien a TV drama Wick of the Candle. Young performed "Reach for the Stars" at the Opening Ceremony of the 1998 Asian Games in Bangkok.

Throughout the 2000s, Young enjoyed widespread mainstream popularity across Southeast Asia, East Asia and South Asia winning multiple national and international awards and was often lauded as "Asia's Queen of Pop" and the "Britney Spears of Asia".
Shalimar Express (Pakistan)
Shalimar Express (Urdu: شالیمار ایکسپریس) is a passenger train operated daily by Pakistan Railways between Karachi and Lahore. The trip takes approximately 18 hours and 40 minutes to cover a published distance of 1,286 kilometres (799 mi), traveling along a stretch of the Karachi–Peshawar Railway Line,

Karachi–Peshawar Line
Karachi–Peshawar Railway Line (Urdu: کراچی–پشاور مرکزی ریل راستہ, romanized: karāčī-pešāvar markazī rēl rāsta) (also referred to as Main Line 1 or ML-1) is one of four main railway lines in Pakistan, operated and maintained by Pakistan Railways. The 1,687 kilometers (1,048 mi) long line starts at Kiamari station, Sindh, and ends at Peshawar Cantonment Station in Khyber Pakhtunkhwa. The railway is dual tracked between Keamari and Shahdara Bagh, and Chaklala and Golra Sharif. With 173 railway stations, the line serves as the country's main passenger and freight line, 75% of the country's cargo and passenger traffic passing through yearly.

In 2016, funding for a six-year, US$6.8 billion upgrade and renovation project was agreed as part of the China Pakistan Economic Corridor, with the average speed to be doubled to 140 kilometers per hour upon completion. The project has been delayed several times since then.
The Swallows of Kabul (film)
The Swallows of Kabul (French: Les hirondelles de Kaboul) is a 2019 internationally co-produced adult animated psychological drama film directed by Zabou Breitman and Eléa Gobé Mévellec. It was screened in the Un Certain Regard section at the 2019 Cannes Film Festival. The film is an adaption of the novel of the same name by Yasmina Khadra.

Psychological drama
Psychological drama, or psychodrama, is a subgenre of drama and psychological fiction literatures that generally focuses upon the emotional, mental, and psychological development of the protagonists and other characters within the narrative, which is highlighted by the drama. It is widely known as one of the main subgenres of psychological fiction; the subgenre is commonly used for films and television series.
Hamaguchi
Hamaguchi (written: 浜口 or 濱口) is a Japanese surname. Notable people with the surname include:

Hideki Hamaguchi (浜口 秀樹; born 1956), Japanese basketball player

Honoo Hamaguchi (浜口 炎; born 1971), Japanese basketball coach

Kanari Hamaguchi (濱口 華菜里; born 1985), Japanese volleyball player

Mark Hamaguchi (浜口マーク; born 1982), Japanese skate boarder, invented the bicycle trick; "Ninja brakes", a dismount technique, running out of a bicycle at its top speed

Masaru Hamaguchi (濱口 優; born 1972), Japanese comedian

Hamaguchi Osachi (濱口 雄幸; 1870 – 1931), 27th Prime Minister of Japan

Ryusuke Hamaguchi (濱口 竜介; born 1978), Japanese film director and screenwriter

Shirō Hamaguchi (浜口 史郎; born 1969), Japanese anime composer

Sota Hamaguchi (濱口 草太; born 1999), Japanese footballer

Toshiyuki Hamaguchi (浜口 俊之; born 1970), Japanese motorcycle racer

Yoshihiro Hamaguchi (浜口 喜博; 1926–2011), Japanese freestyle swimmer

Hamaguchi Osachi
Hamaguchi Osachi (Kyūjitai: 濱口 雄幸; Shinjitai: 浜口 雄幸, 1 April 1870 – 26 August 1931) was a Japanese politician who served as Prime Minister of Japan from 1929 to 1931. Nicknamed the "Lion Prime Minister" (ライオン宰相, Raion Saishō) due to his dignified demeanor and mane-like hair, Hamaguchi served as leading member of the liberal Rikken Minseitō (Constitutional Democratic Party) during the "Taishō Democracy" of interwar Japan. He was a member of the House of Representatives from 1915 until his death. He initially survived an assassination attempt by a right-wing extremist in 1930, but died about nine months later from a bacterial infection in his unhealed wounds.