hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Zoldonrasib
Zoldonrasib, also known as RMC-9805, is an investigational drug that selectively targets the G12D mutation in KRAS dependent cancers. Zoldonrasib functions as molecular glue that forms a non-covalent ligand-mediated protein-protein interaction between cyclophilin A and GTP-bound RAS. Subsequent covalent modification of the mutant Asp12 residue affords selectivity over wild-type RAS.

As of 2025, zoldonrasib is in a phase 1/1b clinical trial for the treatment of KRAS G12D-mutant solid tumors. Preliminary data indicated that KRAS G12D–mutant PDAC patients dosed at 1200 mg daily or 600 mg twice daily achieved a 30% objective response rate (n = 12) and 80% disease control rate (n = 32).

Investigational New Drug
The United States Food and Drug Administration's Investigational New Drug (IND) program is the means by which a pharmaceutical company obtains permission to start human clinical trials and to ship an experimental drug across state lines (usually to clinical investigators) before a marketing application for the drug has been approved. Regulations are primarily at 21 CFR 312. Similar procedures are followed in the European Union, Japan, and Canada due to regulatory harmonization efforts by the International Council for Harmonisation.
Longridge High School
Longridge High School is a coeducational secondary school located in Longridge in the English county of Lancashire.

Previously a community school administered by Lancashire County Council, in October 2023 Longridge High School converted to academy status. The school is now sponsored by The Bay Learning Trust.

Longridge High School offers GCSEs, BTECs and OCR Nationals as programmes of study for pupils.

OCR Nationals
OCR Nationals are vocationally related qualifications which were officially launched by the OCR Board in September 2004.  The qualifications are designed to meet the needs of those seeking vocational education in place of the traditional, theory-intensive, academic route. Although the target audience are teenagers (14-19), the qualifications are also suitable for adult learners, much like the GNVQ.  The OCR Nationals are being phased out, and replaced by the Cambridge Nationals.
Việt Tân
The Vietnam Reform Revolutionary Party (Vietnamese: Việt Nam Canh tân Cách mạng Đảng) or the Việt Tân (lit. 'the New Việt') is a political party that aims to establish liberal democracy and reform Vietnam through peaceful and political means.

The organization was founded on September 10, 1982, with Vice-admiral Hoàng Cơ Minh elected as chairman, which operated underground for two decades. On September 19, 2004, then-chairman Nguyễn Kim introduced Việt Tân as a public organization. Việt Tân's activities are rooted in the promotion of political change in Vietnam.

The organization is outlawed in Vietnam, and the government of Vietnam considers it "a terrorist force". The Office of the UN High Commissioner for Human Rights has described Việt Tân as "a peaceful organization advocating for democratic reform". The U.S. government has stated that there is 'no evidence' that it is a terrorist organization.

The current executive director is Hoang Tu Duy.

Ban (law)
A ban is a formal or informal prohibition of something. Bans are formed for the prohibition of activities within a certain political territory. Some bans in commerce are referred to as embargoes. Ban is also used as a verb similar in meaning to "to prohibit".
2000 North Tyneside Metropolitan Borough Council election
The 2000 North Tyneside Metropolitan Borough Council election to the North Tyneside Metropolitan Borough Council was held in 2000 alongside other local elections. Labour held control of the council after the election.

2000 United Kingdom local elections
The 2000 United Kingdom local elections were held on Thursday 4 May 2000. A third of the seats on each of the Metropolitan Boroughs were elected along with elections in many of the unitary authorities and district councils. There were no elections in Scotland, Wales or Northern Ireland. On the same day, a parliamentary by-election took place in the Romsey constituency in southern England; the Liberal Democrats won the seat from the Conservatives.
Ministry of Education and Research (Moldova)
The Ministry of Education and Research (Romanian: Ministerul Educației și Cercetării) is one of the fourteen ministries of the government of Moldova. The ministry was established on 27 May 1953.

In 2017, as part of the government reform in Moldova, the Ministry of Culture was renamed to Ministry of Education, Culture and Research, and absorbed the Ministry of Education, and the Ministry of Youth and Sports, becoming their legal successor.

Government of Moldova
The government of Moldova (Romanian: Guvernul Republicii Moldova) is the government of the Republic of Moldova. It is housed in the Government House at the Great National Assembly Square in Chișinău, the capital of Moldova. Currently, the president of Moldova is Maia Sandu, while the prime minister of Moldova is Alexandru Munteanu. The current ruling cabinet of Moldova is the cabinet of Alexandru Munteanu, incumbent since 1 November 2025.
Kappa Delta Rho Fraternity House (Champaign, Illinois)
The Kappa Delta Rho Fraternity House is a historic fraternity house located at the University of Illinois at Urbana–Champaign in Champaign, Illinois. The house was built in 1928 for the university's Eta chapter of the Kappa Delta Rho fraternity, which chartered in 1921.

The building has a French Eclectic design, a style popularized in America after World War I by returning soldiers and several photographic studies of French homes. Its key French Eclectic features include a stucco exterior, a limestone entrance surround shaped like a basket handle, a stair tower, casement windows, and a hip roof with flared eaves.

The house was added to the National Register of Historic Places on May 21, 1990.

French Provincial architecture
French Provincial architecture also known as French Eclectic architecture is a revivalist architectural style based on Manor houses or chateaux homes which were built by French aristocrats beginning in the 1600s. The homes are characterized by arched doorways and symmetrically placed elements. They are usually two stories tall with steep hipped roofs. The design came to the United States after American servicemen returned from fighting in France during World War I.
Watson-Sanders House
Watson-Sanders House is a historic home located near Smithfield, Johnston County, North Carolina.  It was built about 1820, and is a two-story, three-bay, frame I-house dwelling.  It has a double engaged front piazza,
an original rear shed piazza.  The interior was remodeled in the Greek Revival style, when the house was moved to its present site in 1854.

It was listed on the National Register of Historic Places in 2001.

Johnston County, North Carolina
Johnston County is a county located in the U.S. state of North Carolina. As of the 2020 census, its population was 215,999. Its county seat is Smithfield. Johnston County is included in the Raleigh-Cary, NC Metropolitan Statistical Area, which is also included in the Raleigh-Durham-Cary, NC Combined Statistical Area, which had an estimated population of 2,368,947 in 2023.
Indian Journal of Occupational and Environmental Medicine
The Indian Journal of Occupational and Environmental Medicine is an official peer-reviewed open-access medical journal published on behalf of the Indian Association of Occupational Health. The journal publishes articles on the subject of occupational and environmental medicine including epidemiology, ergonomics, carcinogenesis, biological monitoring, industrial hygiene, toxicology, applied psychology, and environmental chemistry. The journal is indexed by PubMed.

Environmental medicine
Environmental medicine is a multidisciplinary field involving medicine, environmental science, chemistry and others, overlapping with environmental pathology. It can be viewed as the medical branch of the broader field of environmental health. The scope of this field involves studying the interactions between environment and human health, and the role of the environment in causing or mediating disease. This specialist field of study developed after the realisation that health is more widely and dramatically affected by environmental factors than previously recognized.

Environmental factors in the causation of environmental diseases can be classified into:

Physical

Chemical

Biological

Social (including Psychological and Culture variables)

Ergonomic

Safety

Any combination of the above

In the United States, the American College of Preventive Medicine oversees board certification of physicians in Occupational and Environmental Medicine.
Regie Cabico
Regie Cabico is a Filipino American poet and spoken word artist. He has been featured on two seasons of Def Poetry Jam on HBO (produced by Russell Simmons) and has been called the Lady Gaga of spoken word. He is an "out and proud" gay man.

Filipino Americans
Filipino Americans (Filipino: Mga Pilipinong Amerikano) are Americans of Filipino ancestry. Filipinos in North America were first documented in the 16th century and other small settlements beginning in the 18th century. Mass migration did not begin until after the end of the Spanish–American War at the end of the 19th century, when the Philippines was ceded from Spain to the United States in the Treaty of Paris.

As of 2022, there were almost 4.5 million Filipino Americans in the United States with large communities in California, Hawaii, Illinois, Texas, Florida, Nevada, and the New York metropolitan area. Around one third of Filipino Americans identify as multiracial or multiethnic, with 3 million reporting only Filipino ancestry and 1.5 million reporting Filipino in combination with another group.
Silvia Rinka
Silvia Rinka (later Madeja, born 27 July 1962) is an East German swimmer who competed in the late 1970s and early 1980s. Competing in the breaststroke, she finished eighth in the 200 m breaststroke event at the 1980 Summer Olympics in Moscow.

Rinka is married to Uwe Madeja, who won the silver medal in the canoeing C-2 1000 m event at those same games.

Swimming at the 1980 Summer Olympics – Women's 200 metre breaststroke
The women's 200 metre breaststroke event, included in the swimming competition at the 1980 Summer Olympics, took place on July 23, at the Swimming Pool at the Olimpiysky Sports Complex in Moscow, Soviet Union. In this event, swimmers covered four lengths of the 50-metre (160 ft) Olympic-sized pool employing the breaststroke. It was the thirteenth appearance of the event, which first appeared at the 1924 Summer Olympics in Paris. A total of 25 competitors from 18 nations participated in the event.
Leptolalax applebyi
Leptobrachella applebyi (Appleby's Leaf-litter Toad) (formerly as: Leptolalax applebyi) is a species of frog in the family Megophryidae. It is endemic to Vietnam where it is only known from near its type locality, Song Thanh Nature Reserve, Phước Sơn District in Quảng Nam Province of central Vietnam.

Laptobrachella applebyi is a montane species found near streams. It is a small species even among generally small Laptobrachella: five adult males were recorded to measure 20–21 mm (0.79–0.83 in) in snout-vent length and a single female 22 mm (0.87 in) SVL.

Megophryidae
Megophryidae, commonly known as goose frogs, is a large family of frogs native to the warm southeast of Asia, from the Himalayan foothills eastwards, south to Indonesia and the Greater Sunda Islands in Maritime Southeast Asia, and extending to the Philippines. Fossil remains are also known from North America. As of 2014 it encompasses 246 species of frogs divided between five genera. For lack of a better vernacular name, they are commonly called megophryids.
105th Cavalry Regiment
The 105th Cavalry Regiment is a regiment in the United States Army National Guard.

A regiment with this designation has been formed three times, and due to the lineage system of the United States Army, all three formations are considered completely separate units. The first formation later became the 126th Field Artillery Regiment. The second was initially formed as the 132nd Tank Battalion.

Fort Atkinson, Wisconsin
Fort Atkinson is a city in Jefferson County, Wisconsin, United States. It lies along the Rock River a few miles upstream from Lake Koshkonong. The population was 12,579 at the 2020 census. Fort Atkinson is the largest city located entirely in Jefferson County, as Watertown is split between Jefferson and Dodge counties. Fort Atkinson is a principal city of the Watertown–Fort Atkinson micropolitan statistical area, which is, in turn, a sub-market of the larger Milwaukee–Waukesha–Racine combined statistical area.
Bajar dengan Djiwa
Bajar dengan Djiwa (Indonesian pronunciation: [ˌbajar dəˌŋan ˈd͡ʒiwa]; Perfected Spelling: Bayar dengan Jiwa; Indonesian for "Pay with [One's] Soul") is a believed lost 1941 film from the Dutch East Indies (modern day Indonesia). Directed by R Hu and produced by Ang Hock Liem, it starred A Bakar, Djoewariah, O Parma, Oedjang, RS Fatimah, Soelastri, and Zonder. The story centers on two families torn apart by finances and clashes of personality.

The third film produced by Union Films, Bajar dengan Djiwa featured many actors who had previously appeared in the company's works. It was released by February 1941. Advertisements emphasised the realism of the story, and reviewers praised the film's acting, romance, and humour. Screenings continued until at least 1943, more than a year after Union was closed following the Japanese occupation.

Indonesian orthography
Indonesian orthography refers to the official spelling system used in the Indonesian language. The current system uses the Latin script and is called Ejaan yang Disempurnakan (EYD), commonly translated as Enhanced Spelling, Perfected Spelling or Improved Spelling.
Tony Holden (director)
Tony Holden is a television producer and director. He has been involved in New Zealand television since the 1970s. In the 1970s, he directed episodes of the sketch show A Week of It.

Holden directed a film about the theatre group Red Mole Radio with Pictures - Red Mole (Life is a Zoo) (1980), much of which was filmed in Wellington Zoo.

In the 1980s, he produced and directed The Billy T. James Show (the 1984 season) and episodes of the Roger Hall sitcom Gliding on. He has produced soap opera Shortland Street, and served as executive producer on numerous specials.

Billy T. James
William James Te Wehi Taitoko MBE (17 January 1948 – 7 August 1991), better known by his stage name Billy T. James, was a New Zealand entertainer, comedian, musician and actor. He became a key figure in the development of New Zealand comedy and was a household name during his lifetime.
2024 Brawo Open – Doubles
Pierre-Hugues Herbert and Arthur Reymond were the defending champions but chose not to defend their title.

Sander Arends and Robin Haase won the title after defeating Sriram Balaji and Gonzalo Escobar 4–6, 6–4, [10–8] in the final.

Pierre-Hugues Herbert
Pierre-Hugues Herbert (French pronunciation: [pjɛʁ yɡ ɛʁbɛʁ]; born 18 March 1991) is a French professional tennis player. In doubles, he has completed the Career Grand Slam with titles at the 2015 US Open, the 2016 Wimbledon Championships, the 2018 French Open, the 2021 French Open, and the 2019 Australian Open partnering Nicolas Mahut. His career-high doubles ranking is world No. 2 achieved on 11 July 2016. The pair have also claimed seven ATP Tour Masters 1000 titles and ATP Finals titles in 2019 and 2021. In singles, Herbert has reached four ATP career finals and achieved his career-high singles ranking of world No. 36 on 11 February 2019.
Luigi Giovannozzi
Luigi Giovannozzi (1791 - 1870) was an Italian sculptor, active mainly in Florence in a Neoclassical style.

He was born in Settignano, son of a sculptor Ottavio Giovannozzi. His brother Francesco was also a sculptor. Luigi became a pupil of Lorenzo Bartolini. He was elected honorary academic of the Florentine Academy of Fine Arts in 1870.

Among his works are:

Sculpture of the monument in Santa Croce to the Countess of Albany, Princess Louise of Stolberg-Gedern, widow of Charles Edward Stuart

Decorations for the tomb of Elizabeth Barrett Browning in the Protestant Cemetery, Florence

Decorations for the Tribune of Galileo

Accademia di Belle Arti di Firenze
The Accademia di Belle Arti di Firenze (lit. 'academy of fine arts of Florence') is an instructional art academy in Florence, in Tuscany, in central Italy.

It was founded by Cosimo I de' Medici in 1563, under the influence of Giorgio Vasari. Michelangelo, Benvenuto Cellini and other significant artists have been associated with it.

Like other state art academies in Italy, it became an autonomous degree-awarding institution under law no. 508 dated 21 December 1999, and falls under the administration of the Ministero dell'Istruzione, dell'Università e della Ricerca, the Italian ministry of education and research.

The adjacent (but unaffiliated) Galleria dell'Accademia houses the original David by Michelangelo.
Baptornis
Baptornis ("diving bird") is a genus of flightless, aquatic birds from the Late Cretaceous, some 87-80 million years ago (roughly mid-Coniacian to mid-Campanian faunal stages). The fossils of Baptornis advenus, the type species, were discovered in Kansas, which at its time was mostly covered by the Western Interior Seaway, a shallow shelf sea. It is now known to have also occurred in today's Sweden, where the Turgai Strait joined the ancient North Sea; possibly, it occurred in the entire Holarctic.

Othniel Charles Marsh discovered the first fossils of this bird in the 1870s. This was, alongside the Archaeopteryx, one of the first Mesozoic birds to become known to science.

Holarctic realm
The Holarctic realm is a biogeographic realm that comprises the majority of habitats found throughout the continents in the Northern Hemisphere. It corresponds to the floristic Boreal kingdom. It includes both the Nearctic zoogeographical region (which covers most of North America), and Alfred Wallace's Palearctic zoogeographical region (which covers  North Africa, and all of Eurasia except for  Southeast Asia, the Indian subcontinent, and the southern Arabian Peninsula).

These  regions are further subdivided into a variety of ecoregions. Many ecosystems and the animal and plant communities that depend on them extend across a number of continents and cover large portions of the Holarctic realm. This continuity is the result of those regions’ shared glacial history.
Meffert
Meffert is a German surname. Notable people with the surname include:

Chris Meffert, American politician

Dominik Meffert, German tennis player

Greg Meffert, New Orleans technology chief

Jim Meffert, Minnesota politician and executive

Uwe Mèffert, German designer of mechanical puzzles

William C. Meffert (1842–1918), American politician in Wisconsin

Jim Meffert
Jim Meffert (born 1967) is an American politician and a Senior Consultant at Tecker International, LLC. He was the former Executive Director of Jefferson Action and the Jefferson Center. Before that, he served as the Executive Director of the Minnesota Optometric Association and president of the Minnesota Parent-Teacher Association. He previously worked for the American Medical Association and the American Society of Plastic and Reconstructive Surgeons. Meffert lives in Edina and was the Democratic nominee for Minnesota's 3rd congressional district in 2010.
Richard B. Dominick
Richard Bayard Dominick (September 17, 1919 - May 4, 1976) was an American  ophthalmologist, outdoorsman, and amateur lepidopterist. He is best known for his extensive collection of moths and butterflies in South Carolina. He established the Wedge Entomology Research Foundation for the publication of a series of monographs entitled the Moths of America North of Mexico.

Lepidopterology
Lepidopterology (from Ancient Greek  λεπίδος (lepídos) 'scale'  πτερόν (pterón) 'wing' and  -λογία (-logia)) is a branch of entomology concerning the scientific study of moths and the two superfamilies of butterflies. Someone who studies in this field is a lepidopterist or, archaically, an aurelian.
Ox gall
Ox gall (also spaced oxgall) is bile, also known as "gall", usually obtained from the gallbladder of cows, it is an ingredient in bile soap and mixed with alcohol and used as the wetting agent in paper marbling, engraving, lithography, and watercolor painting. It is a greenish-brown liquid mixture containing cholesterol, lecithin, taurocholic acid, and glycocholic acid.

Glycocholic acid
Glycocholic acid, or cholylglycine, is a crystalline bile acid involved in the emulsification of fats. It occurs as a sodium salt in the bile of mammals. It is a conjugate of cholic acid with glycine. Its anion is called glycocholate.

In a prospective study, positive associations were observed between prediagnostic plasma levels of seven conjugated bile acid metabolites, including glycocholic acid, and colon cancer risk. These findings support experimental data suggesting that high circulating bile acids promote colon cancer risk.
Amanita ovoidea
The European white egg (Amanita ovoidea), bearded amanita or European egg amidella, is a species of fungus of the genus Amanita in the family Amanitaceae. It is a large, white-colored fungus, often tinged with cream. Native to Europe, it is found on plains as well as mountains in the Mediterranean region. It is similar to some deadly poisonous species.

Mushroom poisoning
Mushroom poisoning is poisoning resulting from the ingestion of mushrooms that contain toxic substances. Symptoms can vary from slight gastrointestinal discomfort to death in about 10 days. Mushroom toxins are secondary metabolites produced by the fungus.

Mushroom poisoning is usually the result of ingestion of wild mushrooms after misidentification of a toxic mushroom as an edible species. The most common reason for this misidentification is a close resemblance in terms of color and general morphology of the toxic mushrooms species with edible species. To prevent mushroom poisoning, mushroom gatherers familiarize themselves with the mushrooms they intend to collect, as well as with any similar-looking toxic species. The safety of eating wild mushrooms may depend on methods of preparation for cooking. Some toxins, such as amatoxins, are thermostable and mushrooms containing such toxins will not be rendered safe to eat by cooking.
Bo people (China)
The Bo people (Chinese: 僰人; pinyin: Bó rén) are an ancient people from the Yunnan and Sichuan provinces of Southwestern China. They are famous for their hanging coffins. They were one of the various now extinct peoples from Southern China known collectively in Chinese records as the Baipu. However DNA analysis in 2025 has confirmed  living descendants.

Southwestern China
Southwestern China (Chinese: 西南; pinyin: Xīnán) is a region in the People's Republic of China. It consists of five provincial administrative regions, namely Chongqing, Sichuan, Guizhou, Yunnan, and Tibet.