hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
L-694247
L-694247 is a selective serotonin 5-HT1B and 5-HT1D full agonist, with similar affinities and activational potencies at these two receptors, about 20- to 25-fold greater affinity for the serotonin 5-HT1D receptor over the serotonin 5-HT1A receptor, and negligible affinity for the serotonin 5-HT1E and 5-HT1F receptors.

When L-694247 was injected intraventricularly in dehydrated rats, it inhibited water intake. Pre-treatment with a serotonin 5-HT1D antagonist abolished this effect. Administration of L-694,247 to normally hydrated rats had no effect on water intake.

L-694247 is a 5-substituted tryptamine derivative.

5-HT1A receptor
The serotonin 1A receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter. 5-HT1A is expressed in the brain, spleen, and neonatal kidney. It is a G protein-coupled receptor (GPCR), coupled to the Gi protein, and its activation in the brain mediates hyperpolarization and reduction of firing rate of the postsynaptic neuron. In humans, the serotonin 1A receptor is encoded by the HTR1A gene.
Whiskey sour
A whiskey sour is a mixed drink or shot containing whiskey, lemon juice, and simple syrup, and traditionally garnished with a cherry or sometimes a lemon wedge. It is a blend of sour, bitter, and sweet flavors.

Sometimes, an egg white is included, which is sometimes called a Boston sour. When the whisky used is a Scotch, it is called a Scotch sour. With a few bar spoons of full-bodied red wine floated on top, it is usually referred to as a New York sour. It is shaken and served either straight up or over ice.

The International Bartenders Association recipe includes a garnish of half an orange slice and a maraschino cherry.

A variant of the whiskey sour is the Ward 8, which often is based on bourbon or rye whiskey, and includes both lemon juice and orange juice, and grenadine syrup as the sweetener. The egg white sometimes employed in other whiskey sours is not usually included.

Syrup
In cooking, syrup (less commonly sirup; from Latin: sirupus, from earlier Arabic: شراب; sharāb, beverage, wine) is a thick, viscous, liquid condiment consisting primarily of a solution of sugar in water. It typically contains a large amount of dissolved sugars but shows little tendency to deposit crystals. In its concentrated form, its consistency is similar to that of molasses. The viscosity arises from the multiple hydrogen bonds between the dissolved sugar, which has many hydroxyl (OH) groups.
Wulff-Dieter Heintz
Wulff-Dieter Heintz (3 June 1930 – 10 June 2006) was a German astronomer who worked the latter part of his career in the United States. He was Professor Emeritus of Astronomy at Swarthmore College. He specialised in the characterisation of binary stars using astrometry.

Astrometry
Astrometry is a branch of astronomy that involves precise measurements of the positions and movements of stars and other celestial bodies. It provides the kinematics and physical origin of the Solar System and this galaxy, the Milky Way.
The All Out Fall Out
"The All Out Fall Out" is the third episode of the fifth season of the American comedy-drama television series Entourage. It is the 57th overall episode of the series and was written by executive producer Rob Weiss, and directed by co-executive producer Mark Mylod. It originally aired on HBO on September 21, 2008.

The series chronicles the acting career of Vincent Chase, a young A-list movie star, and his childhood friends from Queens, New York City, as they attempt to further their nascent careers in Los Angeles. In the episode, Vince gets a gig at a birthday party, much to his chagrin. Meanwhile, Ari gets into a prank war with Adam Davies.

According to Nielsen Media Research, the episode was seen by an estimated 1.58 million household viewers and gained a 1.0/2 ratings share among adults aged 18–49. The episode received extremely positive reviews from critics, with particular praise towards Ari's storyline.

Movie star
A movie star (also known as a film star or cinema star) is an actor who is famous for their starring, or leading, roles in movies. The term is used for performers who are marketable stars as they become popular household names and whose names are used to promote movies, for example in trailers and posters. The most prominent movie stars are known in the industry as bankable stars.
Spider Martin
James "Spider" Martin (April 1, 1939 – April 8, 2003) was an American photographer known for his work documenting the American Civil Rights Movement in 1965, specifically Bloody Sunday and other incidents from the Selma to Montgomery marches.

Dolph Briscoe Center for American History
The Dolph Briscoe Center for American History is an organized research unit and public service component of the University of Texas at Austin named for Dolph Briscoe, the 41st governor of Texas. The center collects and preserves documents and artifacts of key themes in Texas and United States history and makes the items available to researchers. The center also has permanent, touring, and online exhibits available to the public. The center's divisions include Research and Collections, the Sam Rayburn Museum, the Briscoe-Garner Museum, and Winedale.
Skyline (band)
Skyline was a newgrass group active in the 1970s and 1980s headed by Tony Trischka. The band consisted of Trischka on banjo, Danny Weiss on guitar and vocals, Dede Wyland on guitar and vocals, Larry Cohen on bass, and Barry Mitterhoff on mandolin. In the last year of their career Dede Wyland left the band and was replaced by Rachel Kalem. They were a major proponent of the "newgrass" sound, known for jazz-infused riffs and extensive use of harmony in their singing. The band released several albums during the '80s, culminating with their final release, Fire of Grace, in 1989. In 1999, they released a retrospective album called Ticket Back.

Some members of the band still play together at times. Weiss, Cohen, and Mitterhoff performed as Silk City, a band named after an old nickname for Paterson, New Jersey. The band was active around 2000–2004, before Mitterhoff left to join Hot Tuna.

Paterson, New Jersey
Paterson (English pronunciation: /ˈpætɚsən/ ⓘ) is the largest city in and the county seat of Passaic County, in the U.S. state of New Jersey. As of the 2020 United States census, Paterson was the state's third-most-populous municipality, with a population of 159,732, an increase of 13,533 (+9.3%) from the 2010 census count of 146,199, which in turn reflected a decline of 3,023 (-2.0%) from the 149,222 counted in the 2000 census. The Census Bureau's Population Estimates Program calculated a population of 156,452 for 2023, making it the 168th-most populous municipality in the nation.

A prominent mill town within the New York–New Jersey metropolitan area, Paterson has been known as Silk City for its once-dominant role in silk production during the latter half of 19th century. It has since evolved into a major destination for Hispanic immigrants as well as for immigrants from Turkey, the Arab world, and South Asia. Paterson has the nation's second-largest per capita Muslim population.
Kristie Macosko Krieger
Kristie Macosko Krieger (born in 1970) is an American film producer, best known for her work alongside director Steven Spielberg. She worked as his assistant (or "associate") starting with the 1998 documentary film The Last Days, and then on his own films from 2001's A.I. Artificial Intelligence to 2011's The Adventures of Tintin. She also became producer on Spielberg's films starting with 2008's Indiana Jones and the Kingdom of the Crystal Skull. For 2015's Bridge of Spies, 2017's The Post, 2021's West Side Story, and 2022's The Fabelmans, she received Academy Award nominations for Best Picture.

Academy Award for Best Picture
The Academy Award for Best Picture is one of the Academy Awards (also known as Oscars) presented annually by the Academy of Motion Picture Arts and Sciences (AMPAS) since the awards debuted in 1929. This award goes to the producers of the film and is the only category in which every member of the Academy is eligible to submit a nomination and vote on the final ballot. The Best Picture category is traditionally the final award of the night and is widely considered the most prestigious honor of the ceremony.

The Grand Staircase columns at the Dolby Theatre in Hollywood, where the Academy Awards ceremonies have been held since 2002, showcase every film that has won the Best Picture title since the award's inception. There have been 621 films nominated for Best Picture and 97 winners.
Eliezer of Touques
Eliezer (ben Solomon) of Touques (רבינו אליעזר מטוך) was a French tosafist, who lived at Touques in the second half of the thirteenth century. He abridged the tosafot of Samson of Sens, Samuel of Évreux, and many others, and added thereto marginal notes of his own, entitled "Gilyon Tosafot," or "Tosafot Gillayon". This abridgment, together with the notes, after undergoing many alterations and receiving several additions from later authorities, was called Tosafot Ṭuk; it forms the foundation of the Tosafot now printed with the Talmud.

Gershon Soncino, who printed Eliezer's tosafot for the first time, says in the preface to Ḳimḥi's Miklol edited by him (Constantinople, 1532–34) that he collected them in various places in France, especially in Chambéry, Savoy.  Eliezer was also the author of a commentary on the Pentateuch, mentioned in a list of works appended to the manuscript of Ibn Janaḥ's Sefer ha-Riḳmah, now in the Bibliothèque Nationale, Paris (No. 1216).

Chambéry
Chambéry (UK: /ˈʃɒ̃bəri/, US: /ˌʃɒ̃beɪˈriː/, French: [ʃɑ̃beʁi]; Arpitan: Chambèri; Italian: Ciamberì) is the prefecture and largest city of the Savoie department in the southeastern Auvergne-Rhône-Alpes region of France.

The population of the commune of Chambéry was 60,251 as of 2022, while the population of the Chambéry metropolitan area was 263,919. The city is located at the foot of the French Alps between Bauges and Chartreuse mountains, and is a railway and highway crossroads.

It has been the historical capital of the Savoy region since the 13th century, when Amadeus V, Count of Savoy, made the city his seat of power. The annexation of Savoy merged the city to France in 1860. Together with other alpine towns Chambéry engages in the Alpine Town of the Year Association for the implementation of the Alpine Convention to achieve sustainable development in the Alpine Arc. Chambéry was awarded Alpine Town of the Year 2006.
Blaschko's lines
Blaschko's lines, also called the lines of Blaschko, are lines of normal cell development in the skin. These lines are only visible in those with a mosaic skin condition or in chimeras where different cell lines contain different genes. These lines may express different amounts of melanin, or become visible due to a differing susceptibility to disease. In such individuals, they can become apparent as whorls, patches, streaks or lines in a linear or segmental distribution over the skin. They follow a V shape over the back, S-shaped whirls over the chest and sides, and wavy shapes on the head. Not all mosaic skin conditions follow Blaschko's lines.

The lines are believed to trace the migration of embryonic cells. They do not correspond to underlying nervous, muscular, or lymphatic systems. The lines are not unique to humans and can be observed in non-human animals with mosaicism.

Alfred Blaschko is credited with the first demonstration of these lines in 1901.

Muscular system
The muscular system is an organ system consisting of skeletal, smooth, and cardiac muscle. It permits movement of the body, maintains posture, and circulates blood throughout the body. The muscular systems in vertebrates are controlled through the nervous system although some muscles (such as the cardiac muscle) can be completely autonomous. Together with the skeletal system in the human, it forms the musculoskeletal system, which is responsible for the movement of the body.
Who Cares? (Gnarls Barkley song)
"Who Cares?" and "Gone Daddy Gone" are songs performed by Gnarls Barkley and are featured on their debut studio album, St. Elsewhere. The songs were released on November 6, 2006 as a double A-side single from that album in the United Kingdom. A week later, on November 13, 2006, the single debuted at No. 60 on the UK Singles Chart. "Gone Daddy Gone" is a cover of the Violent Femmes song. The song peaked at No. 26 on Billboard's Modern Rock Tracks chart, and at No. 35 on Billboard's Adult Top 40 chart. The song "Gone Daddy Gone" is also featured in the soundtrack for the video game Tony Hawk's Project 8, the soundtrack for Forza Motorsport 2 and in the trailer for the Chris Rock film I Think I Love My Wife.

Tony Hawk's Project 8
Tony Hawk's Project 8 is a 2006 skateboarding video game and the eighth installment in the Tony Hawk's series. It was developed by Neversoft and published by Activision in November 2006 for the PlayStation 2, Xbox, Xbox 360, PlayStation 3, and PlayStation Portable. The game complements the release of Tony Hawk's Downhill Jam, which was conversely available on Nintendo systems along with the PlayStation 2 respectively. It received mostly positive reviews. With praise towards the "Nail the Trick" feature and graphics, while the removal of several key features and the absence of online functionality across all three PlayStation versions were criticized.
Damalis
Damalis (Ancient Greek: Δάμαλις) was a coastal town of ancient Bithynia located on the Bosphorus near Chrysopolis. Polybius calls the town Bus or Bous (Βοῦς, meaning cow in Greek).

The name Damalis means 'heifer', and Arrian, quoted by Eustathius, has a story about it.

According to Greek mythology, Io landed when she crossed the strait and people erected a bronze cow on the spot.

Damalis was the name of the wife of the Athenian general Chares of Athens. She accompanied him and while the fleet was stationed near Byzantium, she died. She was said to have been buried here and have been honoured with a monument of the shape of a cow.

Its site is located at Kızkule in Asiatic Turkey.

Bithynia
Bithynia (/bɪˈθɪniə/; Koine Greek: Βιθυνία, romanized: Bithynía) is a geographical region of northwestern Asia Minor (in present-day Turkey), adjoining the Sea of Marmara, the Bosporus, and the Black Sea. It borders Mysia to the southwest, Paphlagonia to the northeast along the Black Sea coast, and Phrygia to the southeast towards the interior of Asia Minor.

Hellenistic Bithynia was an independent kingdom from the 3rd century BC. Its capital Nicomedia was rebuilt on the site of ancient Astacus in 264 BC by Nicomedes I. Bithynia was bequeathed to the Roman Republic in 74 BC, and became united with the Pontus (region) region as the province of Bithynia and Pontus.

In the 7th century it was incorporated into the Byzantine Opsikion theme. It became a border region to the Seljuk Empire in the 13th century, and was eventually conquered by the Ottoman Turks between 1325 and 1333.
Halfbreed (album)
Halfbreed is the debut album by the Keef Hartley Band. The band was formed when Keef Hartley left John Mayall's band after touring and playing on seven albums (some issued later), including being the only performer besides Mayall on The Blues Alone. Halfbreed includes two spoken passages featuring Mayall, as well as several notable British jazz-rock players.

It was voted number 3 in the All-Time 50 Long Forgotten Gems from Colin Larkin's All Time Top 1000 Albums.

All Time Top 1000 Albums
All Time Top 1000 Albums is a book by Colin Larkin, creator and editor of the Encyclopedia of Popular Music. The book was first published by Guinness Publishing in 1994. The list presented is the result of over 200,000 votes cast by the public in record shops, universities, schools and the French music trade show MIDEM – and ranked in order. Each album's entry is accompanied by an annotation with a 100-word review, details of its creation, and notes about the band or artist who recorded it.

The Beatles' Sgt. Pepper's Lonely Hearts Club Band album made the top spot in the first edition, and the same band's Revolver made the top spot in the second, third and pocket editions of the series.
Spreading My Wings
Spreading My Wings is the debut studio album from American rock band World Fire Brigade.  The album, starring percussionist Ken Schalk of Candiria, in addition to Andy Andersson, Mike McCready and Rob Caggiano on guitar, was released on 28 August 2012 via FrostByte Media.  The title track "Spreading My Wings", was published on 4 June 2012.

Rob Caggiano
Robert Caggiano (born November 7, 1976) is an American guitarist and record producer. He was the lead guitarist of the Danish rock band Volbeat from 2013 to 2023 and of thrash metal band Anthrax from 2001 to 2005 and 2007 to 2013. He was also a member of nu metal band Boiler Room.
Vasile Suciu (bishop)
Vasile Suciu (13 January 1873, Kopacsel, Fogaras County – 25 January 1935, Blaj) was a Romanian Greek-Catholic Metropolitan bishop of the Archdiocese of Făgăraș and Alba Iulia, considered to be the most important theologian of the Greek-Catholic Church in Transylvania.

After completing high school in Blaj, he pursued his theological studies in Rome at the  Propaganda Fide, obtaining Ph.D.s in Philosophy (1894) and Theology (1898).

In 1919, he was elected honorary member of the Romanian Academy.

On 1 January 1920, Vasile Suciu was appointed Metropolitan, with approval from the Vatican, and with consent from King Ferdinand I of Romania. During his tenure, a Concordat between the Holy See and the Kingdom of Romania was signed on 10 May 1927, and ratified on 7 July 1929 by the Iuliu Maniu government.

King of Romania
The King of Romania (Romanian: Regele României) or King of the Romanians (Romanian: Regele Românilor) was the title of the monarch of the Kingdom of Romania from 1881 until 1947, when the Romanian Workers' Party proclaimed the Romanian People's Republic following Michael I's forced abdication.
Big Timber (1917 film)
Big Timber is a 1917 American silent film Northwoods/drama produced by the Oliver Morosco Company and distributed by Paramount Pictures. It was directed by William Desmond Taylor and starred Kathlyn Williams and Wallace Reid. It is not known whether the film currently survives, and it may be a lost film.

The film was remade under the same title in 1924 by Universal with William Desmond starring.

William Desmond (actor)
William Desmond (born William Mannion; January 23, 1878 – November 3, 1949) was an American actor. He appeared in more than 200 films between 1915 and 1948. He was nicknamed "The King of the Silent Serials".

Born William Mannion in Salamanca, New York on January 23 1878, he was raised in New York City. He later changed his surname to a stage name. He started out in vaudeville and the legitimate stage before making his film debut. In 1919, he married his co-star Mary McIvor, with whom he had two daughters.

He portrayed a globetrotting hero,  Phineas Fogg the 3rd, in a now lost film serial from the twenties. With the coming of sound he gravitated to older, supporting roles.

On November 3, 1949, Desmond died at age 71 of a heart attack in Los Angeles, California. His cremated remains are stored in the vault at the Chapel of the Pines Crematory, Los Angeles.
Lloyd Sommerlad
Ernest Lloyd Sommerlad (12 April 1919 – 17 April 2014) was an Australian politician.

He was born at Tenterfield to Ernest Christian Sommerlad, also a politician. He attended Sydney Grammar School and then the University of Sydney, where he received a Bachelor of Arts (1940) and a Bachelor of Economics (1946). During World War II he was an instructor of the Light Anti Aircraft School in Dutch New Guinea, holding the rank of captain. On 6 February 1943 he married Mavis Dorothy Patterson, with whom he had three children. On his return he was secretary of the New South Wales Country Press Association, and directed a number of commercial broadcasting companies. From 1955 to 1967 he was a Country Party member of the New South Wales Legislative Council. He died in Sydney in 2014.

Tenterfield, New South Wales
Tenterfield is a regional town in New South Wales, Australia, situated at the junction of the New England and Bruxner highways, along the Northern Tablelands, within the New England region.  At the 2016 census, Tenterfield had a population of 4,066. Tenterfield's proximity to many regional centres and its position on the route between Sydney and Brisbane led to its development as a centre for the promotion of the federation of Australia.
Southland Conference women's soccer tournament
The Southland Conference women's soccer tournament is the conference championship tournament in women's soccer for the Southland Conference. The winner of the tournament receives the conference's automatic bid to the NCAA Division I women's soccer tournament.

Four teams, Lamar, Northwestern State, Southeastern Louisiana, and Texas State are the most winning teams with five titles each.

NCAA Division I women's soccer tournament
The NCAA Division I Women's Soccer Championship, sometimes known as the Women's College Cup, is an American college soccer tournament conducted by the National Collegiate Athletic Association (NCAA), and determines the Division I women's national champion.
Aughrim, County Galway
Aughrim (Irish: Eachroim, meaning 'horse ridge') is a small village in County Galway, Ireland. It is located between the towns of Loughrea and Ballinasloe, along the old N6 national primary road (now listed as the R446 regional road) that used to be the main road between Galway and Dublin. According to the Irish census of 2011, the division had a population of 595. The village is in a civil parish of the same name.

It was in Aughrim that the Marquis de St Ruth prepared the Irish Catholic Jacobite troops for the Battle of Aughrim, which was fought during the Williamite war in Ireland on 12 July 1691. Two ringforts located to the south (in Attidermot townland) are a National Monument.

National monument (Ireland)
A national monument (Irish: séadchomhartha náisiúnta) in Ireland is a structure or site, the preservation of which has been deemed to be of national importance and therefore worthy of state protection. If the land adjoining the monument is essential to protect it, this land may also be protected.

Equivalent monuments in Northern Ireland are listed within the Northern Ireland Sites and Monuments Record and are either in state care or included within the list of scheduled monuments. They are under the protection of the Department for Communities.
Jimmy Rutherford
Jimmy Rutherford was a professional Association footballer. From his short time with Dumfries club Queen of the South he jointly holds the club record for the highest number of goals scored in a season. He averaged more than a goal per game with the club.

Dumfries
Dumfries (Scots: /dʌmˈfriːs/ ⓘ dum-FREESS; from Scottish Gaelic: Dùn Phris Scottish Gaelic pronunciation: [ˌt̪un ˈfɾʲiʃ]) is a market town and former royal burgh in Dumfries and Galloway, Scotland, near the mouth of the River Nith on the Solway Firth, 25 miles (40 km) from the Anglo-Scottish border. Dumfries is the county town of the historic county of Dumfriesshire.

Before becoming King of Scots, Robert the Bruce killed his rival John Comyn III of Badenoch at Greyfriars Kirk in the town in 1306. The Young Pretender had his headquarters here towards the end of 1745. In World War II, the Norwegian armed forces in exile in Britain largely consisted of a brigade in Dumfries.

Dumfries is nicknamed Queen of the South. This is also the name of the town's football club. People from Dumfries are known colloquially in Scots language as Doonhamers.