hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Resatorvid
Resatorvid (TAK-242) is a cyclohexane derivative that was invented by scientists at Takeda in a drug discovery campaign to identify inhibitors of the receptor TLR4. It binds directly to cysteine residue 747 intracellularly, preventing TLR4 binding with TIRAP and thus preventing downstream signal transduction.

A randomized, double-blinded Phase III trial of resatorvid in sepsis was halted early due to lack of efficacy, and the compound has become a widely used tool compound in biological research.

It has antiinflammatory and neuroprotective effects in preclinical models. It has been explored in preclinical studies of several forms of cancer, including multiple myeloma, breast cancer, and ovarian cancer, and has been suggested for study in skin cancers.

Efforts have been made to improve resatorvid by making prodrugs and deuterated derivatives.

Anti-inflammatory
Anti-inflammatory refers to any drug, substance or mechanism that reduces inflammation by lessening the redness, swelling, fever, or pain and loss of function which are part of bodies inflammatory response. Anti-inflammatory drugs are agents that inhibit action or production of inflammatory mediators such as cytokines, histamines and prostaglandins. These drugs reduce pain by inhibiting mechanisms of inflammation, as opposed to opioids, which affect the central nervous system to block pain.

Common anti-inflammatory drugs include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, antileukotrienes, and monoclonal antibodies.
Oregon Trail Scouts
Oregon Trail Scouts is a 1947 American Western film in the Red Ryder film series directed by R. G. Springsteen and written by Earle Snell. The film stars Allan Lane, Robert Blake, Martha Wentworth, Roy Barcroft, Emmett Lynn and Edmund Cobb. The film was released on May 5, 1947, by Republic Pictures.

Earle Snell
Earle Snell (1886–1965) was an American screenwriter. He worked on more than a hundred screenplays, beginning in the silent era. He worked for Universal Pictures as well as variety of smaller independent studios. Much of his later work was for Republic Pictures.
Jeff Beck discography
English rock guitarist Jeff Beck played with multiple groups, including the Yardbirds, the Jeff Beck Group and Beck, Bogert & Appice. He released numerous studio, live, compilation, video and soundtrack albums during his career, as well as over twenty singles.

Beck, Bogert & Appice
Beck, Bogert & Appice was a rock supergroup and power trio formed by English guitarist Jeff Beck, evolving from the Jeff Beck Group. It included bassist Tim Bogert and drummer Carmine Appice, Americans who had played together in Vanilla Fudge and Cactus.
Anna (1739 ship)
Anna was a merchant vessel originally employed as a collier taking coal from Yorkshire to London. The Admiralty chartered her in 1739 and subsequently purchased her to carry additional stores for the squadron of Commodore George Anson on his voyage around the world in 1740–44. She was often referred to as 'Anna Pink', as a 'Pink' is a type of ship with a narrow stern. She lost company with the squadron on 24 April 1741, but rejoined it at the Juan Fernández Islands on 16 August 1741 (Julian calendar) after sheltering for two months in a natural harbour on the South Chilean coast. A subsequent survey found her timbers were too badly damaged for a re-fit, therefore her stores and crew were distributed about the squadron and she was scuttled on 18 August 1741 in Cumberland Bay, Juan Fernández.

John Montagu, 4th Earl of Sandwich
John Montagu, 4th Earl of Sandwich, PC, FRS (13 November 1718 – 30 April 1792) was a British statesman who succeeded his grandfather Edward Montagu, 3rd Earl of Sandwich as the Earl of Sandwich in 1729, at the age of ten. He held various military and political offices during his life, including Postmaster General, First Lord of the Admiralty, and Secretary of State for the Northern Department. He is also known for the claim that he was the inventor of the sandwich.
Zee One
Zee One is a general entertainment channel in Germany which was launched at 8pm on 28 July 2016.

It brought a wide variety of Bollywood productions to Germany, such as series, musicals, comedies, drama films, romantic films, family films and music videos. The station was a commercial free-to-air TV station, with regular programming being interrupted by commercial breaks.

The channel ceased broadcasting on 31 May 2020.

On 13 September 2023, the channel relaunched throughout partnership with Samsung TV Plus.

Samsung TV Plus
Samsung TV Plus is a free ad-supported streaming television (FAST) service owned by Samsung Electronics that was introduced in 2015. The platform was designed to provide free, live streaming content for users with Samsung devices.

As of 2022, the service was available in 24 countries and is viewable within a multitude of Samsung products due to its integration with the Tizen operating system. Samsung TV Plus was one of the five most-used apps on the company's smart TVs in September 2020.
Temple Emanu-El-Beth Sholom
Temple Emanu-El-Beth Sholom, Westmount (French: Synagogue Emanu-El-Beth Sholom de Westmount) is a Reform synagogue in Westmount, Quebec.  The synagogue is the oldest Liberal or Reform synagogue in Canada, incorporated on March 30, 1883 (the Bill of the incorporation was granted under the Act of Incorporation (46 Victoria 1883) by the Quebec Provincial Legislature), and is the only Reform congregation in Quebec.

Westmount
Westmount (French pronunciation: [wɛstmaunt]) is a city on the Island of Montreal, in southwestern Quebec, Canada. Enclaved by the city of Montreal, it had a population of 19,658 in the 2021 Canadian census.

Westmount is home to schools, an arena, a pool, a public library and a number of parks, including Westmount Park, King George Park (also known as Murray Hill Park) and Westmount Summit. The city operates its own electricity distribution company Westmount Light & Power (Hydro-Westmount).  The city is also the location of two Canadian Forces Primary Reserve units: The Royal Montreal Regiment and 34th Signals Regiment.

Traditionally, the community of Westmount has been a wealthy and predominantly anglophone enclave, having been at one point the richest community in Canada. It is still the most affluent neighbourhood in Canada outside of Toronto, Vancouver, and Calgary.
Saga Ballooners
The Saga Ballooners (佐賀バルーナーズ, Saga Barūnāzu) are a professional basketball team based in Saga, Japan. They compete in the first division of the B.League. The team's name is a reference to the Saga International Balloon Fiesta.

B.League
The B.League is a men's professional basketball league in Japan. The league is operated by the Japan Professional Basketball League and was formed as a result of a merger between the National Basketball League that was operated by the FIBA-affiliated Japan Basketball Association and the independently operated bj league. The merger had been mandated by FIBA as a condition to Japan having its membership resumed following suspension in November 2014. The league began play in September 2016.
Piperales
Piperales is an order of flowering plants (4,170 recognized species). It necessarily includes the family Piperaceae but other taxa have been included or disincluded variously over time.  Well-known plants which may be included in this order include black pepper, kava, the many Peperomias, pepper elder, lizard's tail, birthwort, and wild ginger. The two perianthless families Piperaceae and Saururaceae are mainly herbaceous plants possessing highly reduced flowers.

Aristolochia
Aristolochia (English: /əˌrɪstəˈloʊkiə/) is a large plant genus with over 500 species that is the type genus of the family Aristolochiaceae. Its members are commonly known as birthwort, pipevine or Dutchman's pipe and are widespread and occur in the most diverse climates. Some species, like A. utriformis and A. westlandii, are threatened with extinction.

The genus Isotrema is usually included here as Aristolochia subgenus Siphisia, but might be a valid genus. It contains the species with a three-lobed calyx.
Joshua G. Baker
Joshua Gabriel Baker (1852 – March 24, 1935) was a justice of the Louisiana Supreme Court from October 15, 1921, to November 27, 1922.

Born in St. Mary Parish, Louisiana, he was "educated at home and then in Virginia". He was licensed to practice law in 1874, and became an assistant district attorney for Orleans Parish in 1877. In 1883, he became a judge of the criminal court for that parish, holding that office until 1892, and then again from 1896 to 1920. In August 1921, he won election to a seat on the supreme court vacated by the retirement of Justice Frank A. Monroe.

Baker died in New Orleans at the age of 83.

Orleans Parish, Louisiana
Orleans Parish (French: Paroisse d'Orléans; Spanish: Parroquia de Orleans) is a parish of the U.S. state of Louisiana. Since 1870, the parish has been coterminous with the city of New Orleans, and the parish and city are largely governed as a single consolidated city.
Blind deconvolution
In electrical engineering and applied mathematics, blind deconvolution is deconvolution without explicit knowledge of the impulse response function used in the convolution. This is usually achieved by making appropriate assumptions of the input to estimate the impulse response by analyzing the output. Blind deconvolution is not solvable without making assumptions on input and impulse response. Most of the algorithms to solve this problem are based on assumption that both input and impulse response live in respective known subspaces. However, blind deconvolution remains a very challenging non-convex optimization problem even with this assumption.

Impulse response
In signal processing and control theory, the impulse response, or impulse response function (IRF), of a dynamic system is its output when presented with a brief input signal, called an impulse (δ(t)). More generally, an impulse response is the reaction of any dynamic system in response to some external change. In both cases, the impulse response describes the reaction of the system as a function of time (or possibly as a function of some other independent variable that parameterizes the dynamic behavior of the system).

In all these cases, the dynamic system and its impulse response may be actual physical objects, or may be mathematical systems of equations describing such objects.

Since the impulse function contains all frequencies (see the Fourier transform of the Dirac delta function, showing infinite frequency bandwidth that the Dirac delta function has), the impulse response defines the response of a linear time-invariant system for all frequencies.
Malta in the Junior Eurovision Song Contest 2018
Malta was represented at the Junior Eurovision Song Contest 2018 on 25 November 2018 in Minsk, Belarus. The Maltese entrant for the 2018 contest was selected through a national final, organised by the Maltese broadcaster Public Broadcasting Services (PBS) on 8 September 2018. A total of 16 finalists performed original songs for the first time since 2010. Ela Mangion was chosen to represent the island nation with the song "Marchin' On".

Public Broadcasting Services
Public Broadcasting Services Limited (PBS; Maltese: Servizzi ta' Xandir Pubbliku) is the public broadcaster of Malta. PBS is funded by government grants and the sale of commercial airtime. Its TVM channel is Malta's most watched television channel, and its radio station Magic Malta enjoys huge popularity among local and foreign listeners.

Each year on 13 December, PBS hosts an open day, where the public takes a visit in the building and have a look at the sets of the channels and radios.
Joan Young
Joan Young (born Joan Cecilia Frances Wragge; 1 February 1900 – 9 October 1984) was a British character actress of stage, screen and radio, perhaps best known for her portrayal of Lady Chesapeake in Big Bad Mouse and for the wartime radio series, Navy Mixture. She also appeared in several films and TV productions.

Heartbreak House
Heartbreak House: A Fantasia in the Russian Manner on English Themes is a play written by Bernard Shaw during the First World War, published in 1919 and first performed in November 1920 at the Garrick Theatre, New York, followed by a West End production the following year.

The play reflects Shaw's disillusion with post-war Britain. It contrasts cultured but self-absorbed and politically irresponsible people on the one hand and aggressive philistines on the other. Heartbreak House contains a self-mocking depiction of Shaw himself in the central character, Captain Shotover.
Magarsa
Magarsa (Ancient Greek: Μάγαρσα), or Magarsus or Magarsos (Μάγαρσος), or Megarsus or Megarsos (Μέγαρσος), was a town in the eastern part of ancient Cilicia, situated on a height close to the mouth of the river Pyramus. Alexander the Great, previous to the Battle of Issus, marched from Soli to Megarsus, and there offered sacrifices to Athena Megarsis, and to Amphilochus, the son of Amphiaraus, the reputed founder of the place. It seems to have formed the port of Mallus. It was later re-founded and renamed in Hellenistic times as Antiochia ad Pyramum (Antioch on the Pyramus).

Strabo writes that during his time the tombs of Amphilochus and Mopsus were in Magarsa.

Its site is located near Dörtdirek, Karataş, in Asiatic Turkey.

Mopsus (son of Manto)
In Greek mythology, Mopsus, a celebrated seer and diviner, was the son of Manto, daughter of the mythic seer Tiresias, and of Rhacius of Caria or of Apollo himself, the oracular god. Greeks of the Classical age accepted Mopsus as a historical figure, though the anecdotes concerning him bridge legend and myth.
Bruch (surname)
Bruch is a German surname, sometimes used with the locational particle "vom", meaning "of the". Notable people with the surname include:

Gerd vom Bruch (born 1941), German footballer and manager

Klaus vom Bruch (born 1952), German media artist

Walter Bruch (1908–1990), German inventor of PAL analog television standard

PAL
Phase Alternating Line (PAL) is a colour encoding system for analogue television. It was one of three major analogue colour television standards, the others being NTSC and SECAM. In most countries it was broadcast at 625 lines, 50 fields (25 frames) per second, and associated with CCIR analogue broadcast television systems B, D, G, H, I and K. The articles on analogue broadcast television systems further describe frame rates, image resolution, and audio modulation.

PAL was developed by Walter Bruch at Telefunken in Hanover, West Germany, with important input from Gerhard Mahler. The format was patented by Telefunken in December 1962, citing Bruch as inventor, and unveiled to members of the European Broadcasting Union (EBU) on 3 January 1963. When asked why the system was named "PAL" and not "Bruch", the inventor answered that a "Bruch system" would probably not have sold very well ("Bruch" is the German word for "breakage").
2015 Players Championship Finals
The 2015 Players Championship Finals (known for sponsorship reasons as the 2015 Cash Converters Players Championship Finals) was the seventh edition of the PDC darts tournament, the Players Championship Finals, which saw the top 32 players from the 2015 PDC Pro Tour Order of Merit took part. The tournament took place at Butlin's Minehead in Minehead, England, between 27–29 November 2015.

The defending champion Gary Anderson lost to Daryl Gurney 10–4 in the second round.

Michael van Gerwen won his 13th PDC major title by beating Adrian Lewis 11–6 in the final.

Cash Converters
Cash Converters International Limited (colloquially known as Cashies) is an Australian ASX-listed, globally franchised retail and financial services company. The company specialises in the buying and selling of second-hand goods as well as providing a range of financial services including a line of credit, also known as Cashies Loan, and pawnbroking. The company is headquartered in Perth, Western Australia.
Mississippi Opera
The Mississippi Opera is an American opera company located in Jackson, Mississippi founded in 1945. The company presents an annual season of opera consisting of two fully staged opera productions and smaller concerts and workshops open to the public. The company's productions are performed at the Belhaven University Center for the Arts. Composer William Grant Still and soprano Leontyne Price both have associations with the company.

Belhaven University
Belhaven University (Belhaven or BU) is a private evangelical Christian university in Jackson, Mississippi, United States. Founded in 1883, the university offers traditional majors, programs of general studies, and pre-professional programs in Christian ministry, medicine, dentistry, law, and nursing.
Princess Adelheid-Marie of Anhalt-Dessau
Princess Adelheid-Marie of Anhalt-Dessau (German: Adelheid-Marie; French: Adélaïde-Marie) (25 December 1833 – 24 November 1916) was a Princess of Anhalt-Dessau and member of the House of Ascania. As the wife of Adolphe of Nassau, she was Duchess of Nassau from 1851 until 1866 and Grand Duchess of Luxembourg from 1890 until 1905.

Grand duke
Grand duke (feminine: grand duchess) is a European hereditary title, used either by certain monarchs or by members of certain monarchs' families. The title is used in some current and former independent monarchies in Europe, particularly:

in present-day Luxembourg, the last surviving Grand Duchy

historically by the sovereigns of former independent countries, such as Tuscany (from 1569 to 1860, now part of Italy)

in Baden, Hesse, Oldenburg, Mecklenburg-Schwerin, Mecklenburg-Strelitz and Saxe-Weimar-Eisenach (officially simply the Grand Duchy of Saxony) – grand duchies from 1815 to 1918, and all now part of Germany

formerly also in some countries in Northern Europe, such as the Grand Duchy of Finland or the Grand Duchy of Lithuania

currently by claimants to the Russian Imperial Throne (eg. Grand Duke George Mikhailovich of Russia)
Balochi alphabets
Balochi alphabets (Balochi: بلۏچی سیاھگ; Balòci Siyàhag) consist of the Balòrabi script, based on the Perso-Arabic script, and the Balòtin script, based on the Latin script. Both scripts are used for the Balochi language spoken in the Balochistan region of Pakistan, Afghanistan and Iran.

Yodh
Yodh (also spelled jodh, yod, or jod) is the tenth letter of the Semitic abjads, including Phoenician yōd 𐤉, Hebrew yod י‎, Aramaic yod 𐡉, Syriac yōḏ ܝ, and Arabic yāʾ ي‎. It is also related to the Ancient North Arabian 𐪚‎‎‎, South Arabian 𐩺, and Ge'ez የ. Its sound value is /j/ in all languages for which it is used; in many languages, it also serves as a long vowel, representing /iː/.

The Phoenician letter gave rise to the Greek Iota (Ι), Latin I and J,  Cyrillic І, Coptic Iauda (Ⲓ) and Gothic eis .

The term yod is often used to refer to the speech sound [j], a palatal approximant, even in discussions of languages not written in Semitic abjads, as in phonological phenomena such as English "yod-dropping".
Agios Andreas, Katakolo
Agios Andreas is a small settlement in the municipality of Pyrgos near the town of Katakolo, in Elis, Greece. It is situated on the site of ancient Pheia, at a bay opposite the islet of Ichthys or Tiganonisi and the island of Zakynthos. Agios Andreas is located 13 kilometers northwest of Pyrgos and approximately 2 km from the port of Katakolo. It owes its name to an old church, now ruined, dedicated to Andrew the Apostle, who is said to have passed from the place on his journeys. The church was built on the ruins of an ancient temple, which was rebuilt in 1930.

Zakynthos
Zakynthos, also known as Zante, is a Greek island in the Ionian Sea. It is the third largest of the Ionian Islands, with an area of 405.55 km2 (156.6 sq mi), and a coastline 123 km (76 mi) in length. The name, like all similar names ending in -nthos, is pre-Mycenaean or Pelasgian in origin. In Greek mythology, the island was said to be named after Zacynthus, the son of the legendary Arcadian chief Dardanus.

Zakynthos is a tourist destination, especially amongst British tourists, with an international airport served by charter flights from northern Europe. The island's nickname is "Fioro di Levante" (Flower of the East), bestowed upon it by the Venetians, who ruled Zakynthos from 1484 to 1797.
Angianthus halophilus
Angianthus halophilus is a species of flowering plant in the family Asteraceae, and is endemic to the south-west of Western Australia. It is an erect to spreading annual herb with soft, succulent, linear to lance-shaped leaves, oval to hemispherical compound heads of 30 to 60 yellow flowers, and egg-shaped achenes with the narrower end towards the base.

Achene
An achene (/əˈkiːn/; from Ancient Greek  ἀ (a) 'privative' and  χαίνειν (khaínein) 'to gape'), also sometimes called akene and occasionally achenium or achenocarp, is a type of simple dry fruit produced by many species of flowering plants. Achenes are monocarpellate (formed from one carpel) and indehiscent (they do not open at maturity). Achenes contain a single seed that nearly fills the pericarp, but does not adhere to it.  In many species, what is called the "seed" is an achene, a fruit containing the seed. The seed-like appearance is owed to the hardening of the fruit wall (pericarp), which encloses the solitary seed so closely as to seem like a seed coat.
Anápolis
Anápolis (/əˈnæpəlɪs/ ⓘ ə-NAP-əl-iss, Brazilian Portuguese: [ɐˈnapolis]) is a Brazilian city in the state of Goiás. It is located between two capitals, the federal capital Brasília and state capital Goiânia. It is the third most populous city in the state, with 398,869 inhabitants according to the Brazilian Institute of Geographic and Statistics in 2022. It is an important industrial and logistics center in the Brazilian Central-West. Its GDP is R$ 10 billion, approximately US$4.4 billion, which makes it the second largest in the state. The city became an industrial power after the implementation of its Industrial District in 1970.

Saint Anne
According to Christian tradition, Saint Anne (also known as Ann or Anna) was the mother of Mary, the wife of Joachim and the maternal grandmother of Jesus. Mary's mother is not named in the Bible's canonical gospels. In writing, Ann's name and that of her husband Joachim come from New Testament apocrypha, of which the Gospel of James (written perhaps around 150 AD) seems to be the earliest that mentions them. The mother of Mary is mentioned but not named in the Quran.
Indian summer
An Indian summer is a period of unseasonably warm, dry weather that sometimes occurs in autumn in temperate regions of the Northern Hemisphere. Several sources describe a true Indian summer as not occurring until after the first frost, or more specifically the first "killing frost."

William Dean Howells
William Dean Howells (/ˈhaʊəlz/ HOW-əlz; March 1, 1837 – May 11, 1920) was an American realist novelist, literary critic, playwright, and diplomat, nicknamed "The Dean of American Letters". He was particularly known for his tenure as editor of The Atlantic Monthly, as well as for the novels The Rise of Silas Lapham and A Traveler from Altruria, and the Christmas story "Christmas Every Day", which was adapted into a 1996 film of the same name.
Narasinghpur
Narasinghpur is a town and Notified Area Council in Cuttack district in the Indian state of Odisha.

Narasinghpur is named after its discoverer Narasingh who was later overthrown by Sri Mandardhar Harichandana Mohapatra. The small town has its own magnificent history. The local deity of the land is goddess Pragala.

Angul
Angul  (also known as Anugul) is a city, municipality and the headquarters of Angul district in the state of Odisha, India. Angul has an average elevation of 195 m (640 ft) above sea level and total area of 6232 km2. The Angul steel plant, operated by Jindal Steel and Power Limited (JSPL), is a major integrated steel facility and known as largest steel plant in the country.