hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
POLQ
DNA polymerase theta is an enzyme that in humans is encoded by the POLQ gene. This polymerase plays a key role in one of the three major double strand break repair pathways: theta-mediated end joining (TMEJ). Most double-strand breaks are repaired by non-homologous end joining (NHEJ) or homology directed repair (HDR). However, in some contexts, NHEJ and HR are insufficient and TMEJ is the only solution to repair the break.

TMEJ is often described as alternative NHEJ, but differs in that it lacks a requirement for the Ku heterodimer, and it can only act on resected DNA ends. Following annealing of short (i.e., a few nucleotides) regions on the DNA overhangs, DNA polymerase theta catalyzes template-dependent DNA synthesis across the broken ends, stabilizing the paired structure.

Homology directed repair
Homology-directed repair (HDR) is a mechanism in cells to repair double-strand DNA lesions. The most common form of HDR is homologous recombination.  The HDR mechanism can only be used by the cell when there is a homologous piece of DNA present in the nucleus, mostly in G2 and S phase of the cell cycle. Other examples of homology-directed repair include single-strand annealing and breakage-induced replication. When the homologous DNA is absent, another process called non-homologous end joining (NHEJ) takes place instead.
Carlos Quintas
Carlos Miguel Quintas Martins (born 9 April 1951 in Faro) is a Portuguese stage and television actor and singer.

Carlos Quintas turned professional in 1975. Having an acting career simultaneously with being a singer until 1982, he then devoted himself exclusively to the theater.

Quintas has appeared in more than 50 plays by many different authors and styles. He worked at Portugal's Teatro Nacional D. Maria II and is noted for his appearances in musicals such as Godspell, Annie, A Severa, Amalia, My Fair Lady, The Sound of Music, and West Side Story.

He has also appeared in soap operas and sitcoms for the Portuguese TV, including A Visita da Cornélia, E O Resto são Cantigas, A Festa de Sábado á Noite, A Festa Continua, Piano Bar, 1,2,3, Sabadabadu, Noite de Reis and Roda da Sorte. In late 2009, he played the role of Armando del Carlo in the musical La Cage aux Folles by Filipe la Feria, in Teatro Rivoli in Porto.

Maria Severa Onofriana
Maria Severa Onofriana (26 July 1820 – 30 November 1846), also known simply as A Severa, was a Portuguese fado singer and guitarist. She is regarded, in her short life, as the first fado singer to have risen to fame, attaining a near-mythical status after her death. Fado has been described as the Portuguese expression of "the blues", and fado roughly means 'fate'.
Delta Works
The Delta Works (Dutch: Deltawerken) is a series of construction projects in the southwest of the Netherlands to protect a large area of land around the Rhine–Meuse–Scheldt delta from the sea. Constructed between 1954 and 1997, the works consist of dams, sluices, locks, dykes, levees, and storm surge barriers located in the provinces of South Holland and Zeeland.

The aim of the dams, sluices, and storm surge barriers was to shorten the Dutch coastline, thus reducing the number of dikes that had to be raised. Along with the Zuiderzee Works, the Delta Works have been declared one of the Seven Wonders of the Modern World by the American Society of Civil Engineers.

Sluice
A sluice (/slus/ SLOOS) is a water channel containing a sluice gate, a type of lock to manage water flow and water level. There are various types of sluice gates, including flap sluice gates and fan gates.

Sluices are used for channeling water toward a water mill, including for transporting logs from steep hillsides. Different terms are used regionally for sluices; the terms sluice, sluice gate, knife gate, and slide gate are used interchangeably in the water and wastewater control industry.
Nat Levine
Nat Levine (July 26, 1899 – August 6, 1989), was an American film producer. He produced 105 films between 1921 and 1946. Born in New York City, he entered the film industry as an accountant for Metro Pictures and became personal secretary to Metro head Marcus Loew.

He moved to Hollywood in 1925, setting out to produce his own movies. He had made many friends in film distribution, and arranged with them to release his films on the independent state's rights market. He called his company Mascot Pictures.

States' rights
In American political discourse, states' rights are political powers held for the state governments rather than the federal government according to the United States Constitution, reflecting especially the enumerated powers of Congress and the Tenth Amendment. The enumerated powers that are listed in the Constitution include exclusive federal powers, as well as concurrent powers that are shared with the states, and all of those powers are contrasted with the reserved powers—also called states' rights—that only the states possess. Since the 1940s, the term "states' rights" has often been considered a loaded term, a euphemism, or a dog whistle because of its use in opposition to federally mandated racial desegregation and, more recently, same-sex marriage and reproductive rights.
MT-USA
MT-USA (Music Television — USA) was an Irish music television programme broadcast between February 1984 and 1987. Known for the slogan, "Music Television USA - Music never looked better", it was produced by Green Apple Productions, co-founded by the show's presenter Vincent Hanley. MT-USA was broadcast on RTÉ 2 on Sunday afternoons and during the 1984–85 series was repeated on Friday nights. Each edition ran for three hours. Each block of videos was followed by a segment filmed in New York City with Hanley introducing the videos, discussing American music and culture, and interviewing a celebrity. RTÉ described him as Europe's first VJ (video jockey). The videos were primarily American acts, many previously little-known in Ireland., but the show also featured English pop chart acts, as well as up and coming Irish acts such as U2, In Tua Nua & Light a Big Fire. A double-CD and DVD compilation featuring acts from the show's heyday went on release on 16 November 2007.

Video jockey
A video jockey (abbreviated VJ or sometimes veejay) is an announcer or host who introduces music videos and live performances on commercial music television channels such as MTV, VH1, MuchMusic and Channel V.
Shezi, Taiwan
Shezi (Taiwanese Hokkien: Siā-á) is a subdistrict administered by Shilin District in Taipei City, Taiwan. The area was originally an alluvial plain formed by the confluence of the Keelung River and the Tamsui River.

During Typhoon Kit in 1953, severe flooding occurred in the Shezi area. As a result, the Taipei City Government imposed long-term construction restrictions on the innermost areas, including Zhongzhoupou and Xizhoudi—later collectively known as Shezi Island—for a period of 50 years. This policy caused ten villages in the area to experience significantly slower development, making Shezi one of the few lowland areas in Taipei with limited urbanization. The population of Shezi is approximately 10,000.

Keelung River
The Keelung River (Chinese: 基隆河; pinyin: Jīlóng Hé; Wade–Giles: Chi1-lung2 Ho2; Pe̍h-ōe-jī: Ke-lâng-hô) is a river in northern Taiwan.

The Keelung River originates in the mountains west-northwest of the town of Jingtong in Pingxi District, New Taipei City, flows down to a rift valley and then flows ENE to Sandiaoling. Then it flows northward to a point between Jiufen and Keelung City, and then heads back in a general WSW direction to Taipei, where it joins the Tamsui River and flows out to sea. The land around the Keelung river was rich in gold and coal, and many areas were mined.
Wakkerstroom public library
The Wakkerstroom Public Library is a community library located in the village of Wakkerstroom in the Pixley ka Seme Local Municipality, South Africa.

Wakkerstroom itself has existed as a town since 1859, it was then known as Marthinus Wessel Stroom, in honour of the president of the South African Republic at that time.

The library was established in 1890.

The library provides local historical research, cultural enrichment, and community engagement. This is a library that serves all residents of the Pixley ka Seme municipality, addresses apartheid’s legacy.

Pixley ka Seme Local Municipality
Pixley Ka Seme Municipality (Zulu: UMasipala iPixley ka Seme) is a local municipality within the Gert Sibande District Municipality, in the Mpumalanga province of South Africa. Volksrust is the seat of the municipality.

The municipality is named after Pixley ka Isaka Seme, a founder and president of the African National Congress.
Blush With Pride
Blush With Pride (June 5, 1979 – August 16, 2005) was an American Thoroughbred racehorse. A winner of the Kentucky Oaks, Blush With Pride won graded stakes races on both dirt and turf during her racing career. She later went on to become an important broodmare.

Kentucky Oaks
The Kentucky Oaks is a Grade I stakes race for three-year-old Thoroughbred fillies staged annually in Louisville, Kentucky, United States. The race currently covers 1+1⁄8 miles (1,800 m) at Churchill Downs; the horses carry 121 pounds (55 kg). The Kentucky Oaks is held on the Friday before the Kentucky Derby each year. The winner gets $846,300 of the $1,500,000 purse, and a large garland blanket of lilies, resulting in the nickname "Lilies for the Fillies." A silver Kentucky Oaks Trophy is presented to the winner.
Nanterre-Préfecture station
Nanterre–Préfecture (French pronunciation: [nɑ̃tɛʁ pʁefɛktyʁ]) is a RER train station in the commune of Nanterre, west of central Paris, in the department of Hauts-de-Seine in France. The station was opened on 1 October 1973, on the "ligne de St-Germain" connecting Auber and Saint-Germain-en-Laye. It is the westernmost station of the central trunk segment of the RER A. The line splits at this station into multiple branches headed westward; the A1 (to Saint-Germain-en-Laye) and the A3 and A5 branches (to Cergy-le-Haut and Poissy) respectively.

Cergy-le-Haut station
Cergy-le-Haut (French pronunciation: [sɛʁʒi lə o]) is a railway station in Cergy, a western Paris suburb, that serves trains on the RER A line of the Réseau Express Régional network and Line L line of the Transilien network.

The station was built in 1994 and is located underground in a shallow cut and cover tunnel. When first built, the station was located in an area of open fields, now built upon and is part of the network of stations serving the ville nouvelle of Cergy-Pontoise. It was part of a large project to develop the area and smart Parisian style buildings have been built next to the station around a plaza situated above the tracks. Cergy-le-Haut is not yet fully developed so fields are next to the station and next to seven-storey high apartment buildings.

During rush hours it is served by RER A trains every ten minutes and by Transilien Line L every ten minutes.
Bursera laxiflora
Bursera laxiflora is a North American species of trees in the frankincense family in the soapwood order, native to northwestern Mexico. It is fairly common in Sonora (including Tiburón Island) with additional populations in Sinaloa, Baja California Sur, and Socorro Island. There is a report of the species being found in the United States, but it is from the property of the Arizona-Sonora Desert Museum west of Tucson, most likely a cultivated or escaped specimen.

Bursera laxiflora is a small tree with red bark unlike the gray bark of the closely related B. filicifolia. The trunk can reach a diameter of up to 30 cm (12 inches). Leaves are pinnately compound with 5-9 leaflets, with short hairs on both sides. Drupes are egg-shaped and somewhat flattened.

Socorro Island
Socorro Island (Spanish: Isla Socorro) is a volcanic island in the Revillagigedo Islands, a Mexican possession lying 600 kilometres (370 mi) off the country's western coast. The size is 16.5 by 11.5 km (10.3 by 7.1 mi), with an area of 132 km2 (51 sq mi). It is the largest of the four islands of the Revillagigedo Archipelago. The last eruption was in 1993.
Chorizo de Cebu
Chorizo de Cebu, also known as longganisa de Cebu, is a Filipino pork sausage originating from Cebu. It is a type of hamonada (sweet) longganisa. They are distinctively red in color due to the use of achuete seeds. Each link is also usually spherical in shape. It is made from ground lean pork, ground pork fat, salt, saltpeter, sugar, anise liqueur (anisado), paprika, black pepper, garlic, and chilis to taste in a hog casing. It can also be made without the casing. They are usually fried or grilled and eaten with white rice, puso, or garlic rice for breakfast.

Potassium nitrate
Potassium nitrate is a chemical compound with a sharp, salty, bitter taste and the chemical formula KNO3. It is a potassium salt of nitric acid. This salt consists of potassium cations K+ and nitrate anions NO−3, and is therefore an alkali metal nitrate. It occurs in nature as a mineral, niter (or nitre outside the United States). It is a source of nitrogen, and nitrogen was named after niter. Potassium nitrate is one of several nitrogen-containing compounds collectively referred to as saltpetre (or saltpeter in American English).

Major uses of potassium nitrate are in fertilizers, tree stump removal, rocket propellants and fireworks. It is one of the major constituents of traditional gunpowder (black powder). In processed meats, potassium nitrate reacts with hemoglobin and myoglobin generating a red color.
David Eisenbud
David Eisenbud (born 8 April 1947 in New York City) is an American mathematician.  He is a professor of mathematics at the University of California, Berkeley and former director of the then Mathematical Sciences Research Institute (MSRI), now known as Simons Laufer Mathematical Sciences Institute (SLMath). He served as Director of MSRI from 1997 to 2007, and then again from 2013 to 2022.

Simons Laufer Mathematical Sciences Institute
The Simons Laufer Mathematical Sciences Institute (SLMath), formerly the Mathematical Sciences Research Institute (MSRI), is an independent nonprofit mathematical research institution on the University of California campus in Berkeley, California. It is a center for research in mathematics. Each year, over 1,700 mathematicians spend time at MSRI.

The institute was founded in 1982, and its funding sources include the National Science Foundation, private foundations, corporations, and more than 90 universities and institutions. The institute is located at 17 Gauss Way on the Berkeley campus, close to Grizzly Peak in the Berkeley Hills.

The institute has been supported by the National Science Foundation and the National Security Agency as well as private individuals, foundations, corporations, and academic institutions. Jim Simons, founder with his wife of the Simons Foundation and a Berkeley alumnus, was a long-time supporter of the institute and served on the board of trustees.
Gottlob Espenlaub
Gottlob Espenlaub (25 October 1900 – 9 January 1972), nicknamed Espe, was an inventor who specialized in early types of aircraft, specifically gliders and rocket propulsion systems designed for them. He invented a number of different aircraft, focusing  on tailless designs. Espenlaub co-founded the practice of aerotowing.

Glider (aircraft)
A glider is a fixed-wing aircraft that is supported in flight by the dynamic reaction of the air against its lifting surfaces, and whose free flight does not depend on an engine. Most gliders do not have an engine, although motor-gliders have small engines for extending their flight when necessary by sustaining the altitude (normally a sailplane relies on rising air to maintain altitude) with some being powerful enough to take off by self-launch.

There are a wide variety of types differing in the construction of their wings, aerodynamic efficiency, location of the pilot, controls and intended purpose. Most exploit meteorological phenomena to maintain or gain height. Gliders are principally used for the air sports of gliding, hang gliding and paragliding. However some spacecraft have been designed to descend as gliders and in the past military gliders have been used in warfare. Some simple and familiar types of glider are toys such as paper planes and balsa wood gliders.
Eidesvik Offshore
Eidesvik Offshore is a supply, subsea, seismic and cable-laying shipping company. The fleet consists of ten supply ships, both platform supply vessels and anchor handling tug supply vessels, five subsea vessels, five seismic vessels and one cable-laying ship. All the ships are orange in color, and most of them have names starting with Viking. The company is based in Bømlo Municipality, Norway and is listed on the Oslo Stock Exchange. Two thirds of the company is owned by Kristian Eidesvik, who also controls the short sea shipping company Wilson.

Cable layer
A cable layer or cable ship is a deep-sea vessel designed and used to lay underwater cables for telecommunications, for electric power transmission, military, or other purposes. Cable ships are distinguished by large cable sheaves for guiding cable over bow or stern or both. Bow sheaves, some very large, were characteristic of all cable ships in the past, but newer ships are tending toward having stern sheaves only, as seen in the photo of CS Cable Innovator at the Port of Astoria on this page. The names of cable ships are often preceded by "C.S." as in CS Long Lines.

The first transatlantic telegraph cable was laid by cable layers in 1857 to 1858. It briefly enabled telecommunication between Europe and North America before misuse resulted in failure of the line. In 1866 the SS Great Eastern successfully laid two transatlantic cables, securing future communication between the continents.
Burg Liebenstein
Burg Liebenstein is the name of a number of castles:

Burg Liebenstein (Thuringia), Liebenstein, Ilm-Kreis in Thuringia

Burg Liebenstein (Rhein), Kamp-Bornhofen in Rhineland-Palatinate

Burg Liebenstein (Bayern) bei Plößberg in Bavaria

Burgstall Liebenstein, Bad Kötzting in Bayern

Burg Liebenstein (Wartburgkreis) bei Bad Liebenstein in Thuringia

Burg Liebenstein (Tschechien) in Libá (Liebenstein) bei Eger (Cheb) in Czech Republic

Bad Kötzting
Bad Kötzting (German: [baːt ˈkœtstɪŋ] ⓘ; before 2005: Kötzting; Northern Bavarian: Bad Ketzing) is a town in the district of Cham, in Bavaria, Germany, near the Czech border. It is situated in the Bavarian Forest, 15 km (9.3 mi) southeast of Cham.
Ferté
Ferté (French pronunciation: [fɛʁte]) is a surname of French origin, meaning fortress or bastion. Notable people with the surname include:

Alain Ferté (born 1955), French racing driver

Denis-Pierre-Jean Papillon de la Ferté (1727—1794), French civil servant

Henri de La Ferté-Senneterre (1599–1681), French military governor and Marshal of France

Hue de la Ferté (fl. 1220–1235), French trouvère

Jean Charles de la Ferté (1685–1771), French aristocrat, diplomat, and Marshal of France

Jeanne-Françoise Juchereau de la Ferté de Saint-Ignace (1650–1723), Québécois nun

Michel Ferté (1958–2023), French racing driver

Philip Joubert de la Ferté (1887–1965), British Royal Air Force commander

René Ferté (1903–1958), Swiss actor

Stephen of La Ferté (fl. c. 1128–1130), French priest and Latin patriarch of Jerusalem

Hue de la Ferté
Hue de la Ferté (fl. 1220–35) was a French trouvère who wrote three serventois attacking the regency of Blanche of Castile during the minority of Louis IX. He maligns Blanche's partiality to foreigners and singles out Theobald I of Navarre, another trouvère, as unworthy of her support. Hue was a supporter of Pierre de Dreux, Duke of Brittany.

His poem En talent ai que je die is modelled after En chantant m'estuet complaindré (1228–30) by Gace Brulé. Its simple melody is of the form ABABCDD¹D². He modelled Je chantasse volentiers liement after Je chantasse volentiers liement (1228–30) by Chastelain de Couci and Or somes a ce venu after the anonymous Quant li oisellon menu.
Methylglyoxal reductase (NADH-dependent)
In enzymology, methylglyoxal reductase (NADH-dependent) (EC 1.1.1.78) is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are (R)-lactaldehyde and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are methylglyoxal, reduced NADH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (R)-lactaldehyde:NAD+ oxidoreductase. Other names in common use include methylglyoxal reductase, and D-lactaldehyde dehydrogenase.  This enzyme participates in pyruvate metabolism.

Oxidoreductase
In biochemistry, an oxidoreductase is an enzyme that catalyzes the transfer of electrons from one molecule, the reductant, also called the electron donor, to another, the oxidant, also called the electron acceptor. This group of enzymes usually utilizes NADP+ or NAD+ as cofactors. Transmembrane oxidoreductases create electron transport chains in bacteria, chloroplasts and mitochondria, including respiratory complexes I, II and III. Some others can associate with biological membranes as peripheral membrane proteins or be anchored to the membranes through a single transmembrane helix.
DogDay
DogDay is a 1997 graphic adventure game developed by Australian studio Asylum Productions, later known as Eyst and published by Infogrames Europe SA for the PlayStation and Windows. The Japanese PlayStation title translates in English as "Curiosity kills the cat?".

Curiosity killed the cat
"Curiosity killed the cat" is a proverb used to warn of the dangers of unnecessary investigation or experimentation. The original form of the proverb, now rarely used, was "care killed the cat". The modern version dates from at least the 19th century.
Empires & Allies
Empires & Allies was a social network game that was Zynga's first combat and strategy game. The game, the first release by Zynga's Los Angeles studio, launched in twelve languages on June 1, 2011.  G4TV.com writer Jake Gaskill called the release the "biggest launch of any Zynga title to date". Empires & Allies became the fourth most popular game on Facebook within weeks after launch, reaching 33 million monthly active users by the third week of June. The game was a freemium game, meaning there was no cost to play but players had the option of purchasing premium content. The game was taken offline on June 17, 2013.

On May 5, 2015, Empires & Allies was revived and re-released as an entirely different mobile game on Apple's App Store and Google Play worldwide. The old Facebook page was repurposed for this game.

Freemium
Freemium, a portmanteau of the words "free" and "premium", is a pricing strategy by which a basic product or service is provided free of charge, but money (a premium) is charged for additional features, services and virtual (online) or physical (offline) goods that expand the functionality of the free version of the software. This business model has been used in the software industry since the 1980s. A subset of this model used by the video game industry is called free-to-play.

The ethics of freemium, especially the free-to-play subset, were criticized by Touch Arcade and Business Insider in 2014 and 2015.