hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Giredestrant
Giredestrant (also known as GDC-9545, RG6171, or RO7197597) is an investigational oral selective estrogen receptor degrader (SERD) developed by Genentech, a member of the Roche Group, for the treatment of estrogen receptor-positive (ER+), HER2-negative advanced breast cancer, as well as endometrial cancer, ovarian cancer, and other solid tumors.

It is a potent, nonsteroidal compound that antagonizes estrogen effects by competitively binding to both wild-type and mutant estrogen receptors with nanomolar potency. Giredestrant works by inducing an inactive conformation of the estrogen receptor ligand-binding domain and promoting proteasome-mediated degradation of the receptor protein.

As of May 2025, giredestrant is in clinical trials and has received Fast Track designation from the Food and Drug Administration (FDA) for ER+, HER2-negative second- and third-line metastatic breast cancer.

Genentech
Genentech, Inc. is an American biotechnology corporation headquartered in South San Francisco, California. It operates as an independent subsidiary of holding company Roche. Genentech Research and Early Development operates as an independent center within Roche. Historically, the company is regarded as the world's first biotechnology company.

As of July 2021, Genentech employed 13,539 people.
The Card
The Card is a comic novel written by Arnold Bennett in 1911 (entitled Denry the Audacious in the American edition). It was later made into a 1952 movie, starring Alec Guinness.

Like much of Bennett's best work, it is set in the Staffordshire Potteries. It chronicles the rise of Edward Henry ("Denry") Machin from washerwoman's son to Mayor of Bursley (a fictitious town based on Burslem). This is accomplished through luck, initiative and a fair bit of cheek (in slang a card is a 'character', an 'original'; a clever, audacious, person).

Denry Machin returned, as the slightly more mature "Edward Henry", in Bennett's sequel The Regent (1913) (titled The Old Adam in its first US edition).

Comic novel
A comic novel is a novel-length work of humorous fiction. Many well-known authors have written comic novels, including P. G. Wodehouse, Henry Fielding, Mark Twain, and John Kennedy Toole. Comic novels are often defined by the author's literary choice to make the thrust of the work—in its narration or plot—funny or satirical in orientation, regardless of the putative seriousness of the topics addressed.
Zahir Hassan
Zahir bin Hassan (born 24 March 1959) is a Malaysian politician who has served as the Member of Parliament (MP) for Wangsa Maju since November 2022. He is a member and was the Chairman of the Federal Territories of the People's Justice Party (PKR), a component party of the Pakatan Harapan (PH) and formerly the Pakatan Rakyat (PR) coalitions. He has served as the Chief Organising Secretary of PKR since July 2022.

Wangsa Maju (federal constituency)
Wangsa Maju is a federal constituency in the Federal Territory of Kuala Lumpur, Malaysia, that has been represented in the Dewan Rakyat since 1995.

The federal constituency was created in the 1994 redistribution and is mandated to return a single member to the Dewan Rakyat under the first past the post voting system.

With over 13,000 people per km2, Wangsa Maju has the highest population density among all parliamentary constituencies in Malaysia.
Pinewood (Gotham)
"Pinewood" is the eighteenth episode of the second season, and 40th episode overall from the Fox series Gotham. The episode was written by co-executive producer Robert Hull and Megan Mostyn-Brown and directed by executive producer John Stephens in his first Gotham episode directed. It was first broadcast on April 18, 2016. In the episode, Bruce and Alfred set to find out information about a program called Pinewood Farms which had something to do with Thomas Wayne's death and involvement while Gordon sets out to find The Lady and Dr. Strange continues his experiments.

The episode received positive reviews, with critics praising the character development, resolution of the Waynes' murderer and the plot twists.

James Frain
James Frain  is an English actor. His best known television roles include Thomas Cromwell in the Showtime/CBC historical drama The Tudors (2007–2009), Franklin Mott in the HBO drama True Blood (2010), Warwick the Kingmaker in the BBC drama serial The White Queen (2013), John Sumner in the Sky/Canal+ crime drama The Tunnel (2013), Ferdinand Chevalier in the BBC/Space sci-fi thriller Orphan Black (2015–2017), Theo Galavan/Azrael in Fox's Gotham (2015–2016), and Sarek in Star Trek: Discovery (2017–2019).

In film, he is best known for playing Daniel Barenboim and Álvaro de la Quadra in the biographical dramas Hilary and Jackie and Elizabeth, respectively (both 1998), Bassianus in the Shakespeare adaptation Titus (1999), and Gérard de Villefort in the historical drama The Count of Monte Cristo (2002).
Notsé
Notsé (also Notsie or Nuatja) is a town in the Plateaux Region of Togo. It is the capital of Haho Prefecture and is situated 95 km north of the capital Lomé. The town was formed around 1600 by the Ewe people, after they were displaced westward by the expansion of the Yoruba.

Plateaux Region, Togo
Plateaux Region (French: Région des Plateaux) is one of Togo's five regions.

Atakpamé is the regional capital. It is the largest region in terms of area and has the second largest population (after the Maritime Region). Other major cities in the Plateaux region include Kpalimé and Badou. The highest point of the country, Mount Agou, is located within this region.

Plateaux is located north of Maritime Region and south of Centrale Region. In the west, it borders the Volta Region of Ghana, and in the east it borders three departments of Benin: Collines to the northeast; Zou to the east; and Kouffo to the southeast.

Plateaux is divided into the prefectures of:

Agou Prefecture

Amou Prefecture

Danyi Prefecture

Est-Mono Prefecture

Haho Prefecture

Kloto Prefecture

Moyen-Mono Prefecture

Ogou Prefecture

Wawa Prefecture
Steveville
Steveville is a ghost town in southeastern Alberta, Canada near Brooks. In 1910, the community had a general store. Named after Steve Hall, a local homesteader, the community never attracted a large population. The Hall family operated a number of businesses in Steveville, including a ferry across the Red Deer River, a boarding house, and the general store and post office.

Steveville lies near the northwest boundary of Dinosaur Provincial Park at the edge of the badlands within the Red Deer River valley, and it is most notable as the discovery location for many specimens of dinosaurs. These come from the Dinosaur Park Formation of Late Cretaceous (Campanian) age and include remains of Styracosaurus, Daspletosaurus, Corythosaurus, Struthiomimus, and others.

Amateur palaeontologist Irene Vanderloh (1917–2009) was born in Steveville. In 1974, she discovered the holotype of the theropod dinosaur Saurornitholestes near Steveville.

Dinosaur Provincial Park
Dinosaur Provincial Park is a UNESCO World Heritage Site situated 220 kilometres (137 mi) east of Calgary, Alberta, Canada; or 48 kilometres (30 mi) northeast of Brooks.

The park is situated in the Red Deer River valley, which is noted for its striking badland topography, and abundance of dinosaur fossils. The park is well-known for being one of the richest dinosaur fossil locales in the world. Fifty-eight dinosaur species have been discovered at the park and more than 500 specimens have been removed and exhibited in museums around the globe. The renowned fossil assemblage of nearly 500 species of life, from microscopic fern spores to large carnivorous dinosaurs, justified its becoming a World Heritage Site in 1979.
Daxuecheng station (Tianjin Metro)
Daxuecheng Station (Chinese: 大学城站), literally University Town Station or Higher Education Mega Center Station in English, is a station of Line 3 of the Tianjin Metro, Tianjin, China. It started operations on 1 October 2012.

Tianjin Metro
The Tianjin Metro or Tianjin Rail Transit is the rapid transit system in the city of Tianjin, which was the second city in mainland China after Beijing to operate a subway system (the Beijing Subway opened in 1971). First opened in 1984, the system currently has 13 operating lines and 258 stations spanning 370 km (230 mi).
1975 Metro Manila Film Festival
The 1st Metropolitan Film Festival (later the Metro Manila Film Festival) was held on September 21, 1975, in Manila to commemorate the third anniversary of martial law and President Ferdinand Marcos' New Society program.

The film Diligin Mo ng Hamog ang Uhaw na Lupa received most of the 1975 awards, winning six major awards including the Dangal ng Bagong Lipunan and Best Actor for Joseph Estrada. Batu-Bato sa Langit and Kapitan Kulas came in second and third respectively. The feature film Araw-Araw, Gabi-Gabi won one award, Best Actress for Charito Solis.

Nora Aunor's entry, NV Productions' Batu-Bato sa Langit (directed by Luciano B. Carlos), won as 3rd Best Picture. Vilma Santos, on the other hand, gave a notable performance in Roma Films' Karugtong ang Kahapon.

Vilma Santos
Rosa Vilma Tuazon Santos (born November 3, 1953) is a Filipino actress and politician. Known for her versatile work on screen, she began her career as a child actress in the 1960s and was one of the biggest box-office draw from the 1970s to early 1980s. Her accolades include a Dhaka International Film Festival Award, thirteen FAMAS Awards, eleven Gawad Urian, and five Luna Awards. She served as the Mayor of Lipa from 1998 to 2007, then as Governor of Batangas in 23rd and 25th congress. She also served as the representative for Batangas' 6th district from 2016 to 2022, and as the House Deputy Speaker from 2019 to 2022.
Sant Kabir Award
Sant Kabir Award is an Indian Government award conferred to outstanding weavers who have made valuable contribution in keeping alive the handloom heritage. It was established for dedication in building up linkages between the past, present and future through dissemination of knowledge on traditional skills and designs by Ministry of Textiles, Government of India. The award was christened in the memory of sant Kabir, a 15th-century mystic poet and sant of India.

The award is presented by the President of India, along with Shilp Guru Awards and National Awards to Master Craftspersons and master weavers, introduced in 1965.

Sant (religion)
A sant (Sanskrit: सन्त्; IAST: Sant; [sɐn̪t̪]) is a human being revered as a "truth-exemplar" for their abnormal level of "self, truth, [and] reality" in Indian religions, particularly Hinduism, Jainism, Sikhism, and Buddhism. In Sikhism it is used to describe a being who has attained spiritual enlightenment and divine knowledge and power through union with God.
Scotura annulata
Scotura annulata is a moth of the family Notodontidae. It is found from Texas, south through Central America (including Panama and Costa Rica) to Argentina.

The larvae have been recorded on Hybanthus prunifolius in Panama. Other recorded host plants include Acalypha diversifolia, Chamaedorea, Randia and Meliosma species.

Meliosma
Meliosma is a genus of flowering plants in the family Sabiaceae, native to tropical to warm temperate regions of southern and eastern Asia and the Americas. It is traditionally considered to contain about 100 species; some botanists take a much more conservative view accepting only 20-25 species as distinct. They are trees or shrubs, growing to 10–45 m tall.

Fossil evidence shows the genus formerly had a much wider range in the Northern Hemisphere, including Europe and central Asia until the late Pliocene ice ages, and somewhat earlier in North America. At least 17 species of Meliosma are known from Peru.

The Indian awlking (Choaspes benjaminii) is one of the Lepidoptera whose caterpillars feed on Meliosma; they have been found on M. pungens, rhoifolia, M. rigida, and M. squamulata.
Barfin flounder
The barfin flounder (Verasper moseri) is a flatfish of the family Pleuronectidae. It is a demersal fish that lives on sandy, muddy bottoms at depths of up to 900 metres (3,000 ft). It can reach up to 70 centimetres (28 in) in length and can weigh as much as 4.0 kilograms (8.8 lb). Its native habitat is the northwestern Pacific, specifically the Sea of Okhotsk, Japan's northern Pacific coast, the Strait of Tartary and the Kuril Islands.

Strait of Tartary
The Strait of Tartary or Gulf of Tartary (Russian: Татарский пролив; Chinese: 韃靼海峽; pinyin: Dádá hǎixiá; Korean: 타타르 해협) or Mamiya Strait (Japanese: 間宮海峡, romanized: Mamiya kaikyō) is a strait in the Pacific Ocean dividing the Russian island of Sakhalin from mainland Asia (South-East Russia), connecting the Sea of Okhotsk (Nevelskoy Strait) on the north with the Sea of Japan on the south. It is 632 km (393 mi) long, 7–23 km (4.3–14.3 mi) wide, and only 4 m (13 ft) deep at its shallowest point.
Meike de Bruijn
Meike de Bruijn (born 15 April 1970 in Amsterdam) is a road cyclist from Netherlands. She represented her nation at the 1995 UCI Road World Championships and 1997 UCI Road World Championships in the women's time trial. In 1995 she won a stage in the French stage race Laines-aux-Bois. In 1996 she won the silver medal at the Dutch National Road Race Championships. In the general classification of the 2000 Gracia–Orlová she finished second.

Dutch National Road Race Championships
The Dutch National Road Race Championships take place annually, on the weekend prior to the start of the Tour de France. First held in 1888, today it is organized by the Top Sports Group, commissioned by the KNWU.
Albert Español
Albert Español Lifante (born 29 October 1985) is a Spanish water polo player. At the 2012 Summer Olympics, he competed for the Spain men's national water polo team in the men's event. He is 6 ft 2 inches tall. At club level, he plays for Spanish powerhouse CN Atlètic-Barceloneta.

Water polo at the 2012 Summer Olympics – Men's tournament
The men's tournament of water polo at the 2012 Summer Olympics at London, Great Britain, began on 29 July and lasted until 12 August 2012. All games were held at the Water Polo Arena.

Teams from twelve nations competed in the tournament and were seeded into two groups for the preliminary round. A total of 42 games were played, 30 of them in the preliminary round.
Pyramid Peak (Pierce County, Washington)
Pyramid Peak is a 6,937-foot (2,114-metre) mountain summit located in Mount Rainier National Park in Pierce County of Washington state. It is part of the Cascade Range and overlooks Indian Henry's Hunting Ground. It is situated at the base of the Success Cleaver, south of South Tahoma Glacier, and southwest of Pyramid Glacier. The summit provides views of Mount Rainier, Mount Adams, Mount St. Helens, and peaks of the Tatoosh Range. Precipitation runoff from Pyramid Peak drains into Pyramid Creek, Tahoma Creek, and Fishers Horn Pipe Creek, which are all tributaries of the Nisqually River.

Pyramid Glacier
The Pyramid Glacier is actually a scattering of glaciers and snowfields located on the south-southwestern flank of Mount Rainier in Washington. It covers 0.2 square miles (0.5 km2) and contains 400 million ft3 (11 million m3) of ice. The glaciers lie at an elevation ranging from about 7,000 feet (2,100 m) to 9,000 ft (2,700 m). The Success Divide separates this glacier from the South Tahoma Glacier to the west. Both the Success Glacier and lower end of the Kautz Glacier border this glacier on the eastern side. Meltwater from the glacier drains into the Nisqually River.

In a June 2023 report from the National Park Service, the glacier had lost 34% of its volume between 2015 and 2021. Based on 2022 satellite imagery, glaciologist Mauri Pelto declared Pyramid Glacier dead.
Caerleon Comprehensive School
Caerleon Comprehensive School (Welsh: Ysgol Gyfun Caerllion) is an 11–18 mixed, English-medium community Secondary School and Sixth Form in Caerleon, Newport, Wales.

The school was ranked 6th in the WalesOnline Best Secondary Schools in Wales 2018 awards, and was given the title of best school in the area.

Community school (England and Wales)
A community school in England and Wales is a type of state-funded school in which the local education authority employs the school's staff, is responsible for the school's admissions and owns the school's estate. The formal use of this name to describe a school derives from the School Standards and Framework Act 1998.
Jonathan Reed Winkler
Jonathan Reed Winkler (born 1975) is a historian and a professor of history at Wright State University in Dayton, Ohio.  He teaches and researches on U.S. foreign relations, U.S. military and naval history, international history, security studies and strategic thought.  He is the author of Nexus: Strategic Communications and American Security in World War I (Harvard University Press, 2008), winner of several prizes including the Birdsall Prize of the American Historical Association. His articles, commentaries and reviews have appeared in Diplomatic History, The Journal of Military History, the Naval War College Review, and other venues.

Naval War College Review
The Naval War College Review is a quarterly peer-reviewed academic journal published by the United States Navy's Naval War College. It covers public policy matters of interest to the maritime services and was established in 1948.
2011 Open Diputación Ciudad de Pozoblanco – Men's singles
Rubén Ramírez Hidalgo was the defending champion; however, he was eliminated already in the first round by Ivo Klec.

Kenny de Schepper eliminated Íñigo Cervantes Huegun, Adrian Mannarino, Roberto Bautista Agut, Illya Marchenko and won in the final against Iván Navarro, 2–6, 7–5, 6–3.

Adrian Mannarino
Adrian Mannarino (born 29 June 1988) is a French professional tennis player. He has a career-high ATP singles ranking of world No. 17, achieved on 29 January 2024 and a best doubles ranking of No. 73, reached on 2 May 2016. He is currently the No. 5 singles player from France. He has won five ATP Tour singles titles, three on hardcourts and two on grass.
Clara Gómez Caro
Clara Gómez Caro (born 12 August 1949) is a Mexican politician from the Institutional Revolutionary Party (PRI). 
In the 2009 mid-terms she was elected to the Chamber of Deputies 
to represent Jalisco's 9th district during the 61st session of Congress.

2009 Mexican legislative election
Legislative elections were held in Mexico on 5 July 2009. Voters elected 500 new deputies (300 by their respective constituencies and 200 by proportional representation) to sit in the Chamber of Deputies for the 61st Congress.
First Step Act
The First Step Act, formally known as the Formerly Incarcerated Reenter Society Transformed Safely Transitioning Every Person Act, is a bipartisan criminal justice bill passed by the 115th U.S. Congress and signed by President Donald Trump in December 2018. The act enacted several changes in U.S. federal criminal law aimed at reforming federal prisons and sentencing laws in order to reduce recidivism, decreasing the federal inmate population, and maintaining public safety.

Recidivism
Recidivism (/rɪˈsɪdɪvɪzəm/; from Latin: recidivus 'recurring', derived from re- 'again' and cadere 'to fall') is the act of a person repeating an undesirable behavior after they have experienced negative consequences of that behavior, or have been trained to extinguish it. Recidivism is also used to refer to the percentage of former prisoners who are rearrested for a similar offense.

The term is frequently used in conjunction with criminal behavior and substance abuse. Recidivism is a synonym of relapse, which is more commonly used in medicine and in the disease model of addiction.
NGC 7044
NGC 7044 is an open cluster located in the Cygnus constellation. Containing approximately 742 stars, it was discovered by 18th century English astronomer William Herschel on 17 October 1786. It is located approximately 10,676.729 light years, (3273.5 pc), from the Earth. Given its visual magnitude of 12, NGC 7044 is visible with the help of a telescope having an aperture of 8 inches (200mm) or more. NGC 7024 is moving towards the Sun with a radial velocity of -48.444 km/s.

Inch
The inch (symbol: in or ″) is a unit of length in the British Imperial and the United States customary systems of measurement. It is equal to ⁠1/36⁠ yard or ⁠1/12⁠ of a foot. Derived from the Roman uncia ("twelfth"), the word inch is also sometimes used to translate similar units in other measurement systems, usually understood as deriving from the width of the human thumb.

Standards for the exact length of an inch have varied in the past, but since the adoption of the international yard during the 1950s and 1960s the inch has been based on the metric system and defined as exactly 25.4 mm.
Shaba North
Shaba North (also mentioned as Kapani Tonneo) was the launch site of the first rockets launched by Orbital Transport und Raketen AktienGesellschaft, or Orbital Forwarding Company in English ("OTRAG").

It is located at the edge of a mesa in Shaba (now Katanga province), the Democratic Republic of Congo. In 1976 Luvua Airport was built to supply the site.

In 1977 and in 1978 three test flights of OTRAG rockets were launched from Shaba North.

In 1979 OTRAG stopped launching rockets from Shaba North after pressure from the Soviet Union, whose leaders were concerned about German interests obtaining powerful long-range rockets. Its launching activities were later moved to Sabha, Libya.

Katanga Province
Katanga was one of the four large provinces created in the Belgian Congo in 1914.
It was one of the eleven provinces of the Democratic Republic of the Congo between 1966 and 2015, when it was split into the Tanganyika, Haut-Lomami, Lualaba, and Haut-Katanga provinces. Between 1971 and 1997 (during the rule of Mobutu Sese Seko when Congo was known as Zaire), its official name was Shaba Province.

Katanga's area encompassed 497,000 square kilometres (192,000 sq mi). Farming and ranching are carried out on the Katanga Plateau. The eastern part of the province is a rich mining region which supplies cobalt, copper, tin, radium, uranium, and diamonds. The region's former capital, Lubumbashi, is the second-largest city in the Congo.
Grootfontein Constituency
Grootfontein Constituency is an electoral constituency in the Otjozondjupa Region of Namibia. It had 21,595 inhabitants in 2004 and 16,629 registered voters in 2020. The constituency consists of the town of Grootfontein and the surrounding rural area. Until 1998 it also contained the area that today is Tsumkwe Constituency. It was split off following a recommendation of the Second Delimitation Commission of Namibia, and in preparation of the 1998 general election.

1998 Namibian local and regional elections
Namibia held two subnational elections in 1998. Local Authority Council elections were held on 16 February 1998.  Regional Council elections were held from 30 November to 1 December 1998. SWAPO again emerged as the party that gained control of a clear majority of Local Authority Councils and Regional Councils.
Peter Murphy (rugby league)
Peter Murphy (born 27 July 1941) is a Scottish-born former professional rugby league footballer who played in the 1950s and 1960s. He played at club level for South Newington ARLFC (in Kingston upon Hull), Hull Kingston Rovers, Wakefield Trinity (Trial), Dee Street Recreation ARLFC (in Kingston upon Hull) and Castleford (A-Team Trial), as a wing (4-matches for Hull Kingston Rovers), or more usually as a prop or second-row.

Cornish Pirates
The Cornish Pirates (Cornish: An Vorladron Gernewek) are a professional rugby union team who play in the Champ Rugby, the second level of the English rugby union pyramid, and are the premier Cornish rugby club. The Cornish Pirates team are the 'First XV' of the Penzance & Newlyn Rugby Football Club, and play and train at their home ground, the Mennaye Field in Penzance.