hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
T790M
T790M, also known as Thr790Met, is a gatekeeper mutation of the epidermal growth factor receptor (EGFR). The mutation substitutes a threonine (T) with a  methionine (M) at position 790 of exon 20, affecting the ATP binding pocket of the EGFR kinase domain. Threonine is a small polar amino acid; methionine is a larger nonpolar amino acid. Rather than directly blocking inhibitor binding to the active site, T790M increases the affinity for ATP so that the inhibitors are outcompeted; irreversible covalent inhibitors such as osimertinib can overcome this resistance.

Methionine
Methionine (symbol Met or M) (/mɪˈθaɪəniːn/) is an essential amino acid in humans. Compared to other amino acids, methionine has particularly decisive biosynthetic roles. It is the precursor to the amino acid cysteine and the pervasive methylation agent rSAM. Methionine is required for protein synthesis, which is initiated by N-formylmethionine-sRNA.

Methionine was first isolated in 1921 by John Howard Mueller. It is encoded by the codon AUG. It was named by Satoru Odake in 1925, as an abbreviation of its structural description 2-amino-4-(methylthio)butanoic acid.
Bridle Path–Sunnybrook–York Mills
Bridle Path–Sunnybrook–York Mills is a municipal and census district in Toronto, Ontario, Canada, and it is the name officially designated by Toronto City Hall.  Traditionally, Torontonians regard this area as five distinct neighbourhoods that were formerly in North York before it was amalgamated into Toronto in 1998.  The area is part of the federal and provincial electoral district of Don Valley West, and Toronto electoral ward 25: Don Valley West (North).

Metropolitan Toronto
The Municipality of Metropolitan Toronto was an upper-tier level of municipal government in Ontario, Canada, from 1953 to 1998. It was made up of the old city of Toronto and numerous townships, towns and villages that surrounded Toronto, which were starting to urbanize rapidly after World War II. It was commonly referred to as "Metro Toronto" or "Metro".

Passage of the 1997 City of Toronto Act caused the 1998 amalgamation of Metropolitan Toronto and its constituents into the current City of Toronto. The boundaries of present-day Toronto are the same as those of Metropolitan Toronto upon its dissolution: Lake Ontario to the south, Etobicoke Creek and Highway 427 to the west, Steeles Avenue to the north, and the Rouge River to the east.
1999 Rally de Portugal
The 1999 Rallye de Portugal was a motor racing event for rally cars that was held over four days between 21 and 24 March 1999. It marked the 33rd running of the Rally de Portugal, and was the fourth round of the 1999 World Rally Championship season. The 1999 event was based in the municipality of Matosinhos in Portugal and was contested over twenty one special stages, covering a total competitive distance of 358.85km (222.98 miles).

Colin McRae was the defending rally winner, as was Ford Motor Co Ltd. Having won two of three rallies of the season so far, Tommi Makinen lead the championship with twenty points; seven more than closest rival Didier Auriol.

McRae, along with co-driver Nicky Grist won the rally, their second win in a row, accelerating them to second in the championship.

Ford World Rally Team
The Ford World Rally Team, also known as the Ford Motor Co. Team prior to 2005, was Ford Motor Company's factory World Rally Championship team. It was a regular competitor in the series from the 1970s until withdrawing following the 2012 season.
Scleromitrion diffusum
Scleromitrion diffusum, synonyms including Hedyotis diffusa, is a species of flowering plant in the family Rubiaceae. It is a herb used in traditional Chinese medicine, known as Chinese: 白花蛇舌草; pinyin: báihuā shéshécǎo; lit. 'white flower snake-tongue grass', sometimes abbreviated to 蛇舌草 shéshécǎo. It is sometimes combined with Siraitia grosvenorii (simplified Chinese: 罗汉果; traditional Chinese: 羅漢果; pinyin: luóhànguǒ) and Scutellaria barbata (Chinese: 半枝莲) to make hot drinks like lohoguo of guongsei (simplified Chinese: 罗汉果蛇舌草精; traditional Chinese: 羅漢果蛇舌草精; pinyin: luóhànguǒ shéshécǎo jīng) or luohanguo pearl and sheshecao beverage.

Rubiaceae
Rubiaceae (/ruːbiˈeɪsiːˌiː, -siˌaɪ/) is a family of flowering plants, commonly known as the coffee, madder, or bedstraw family. It consists of terrestrial trees, shrubs, lianas, or herbs that are recognizable by simple, opposite leaves with interpetiolar stipules and sympetalous actinomorphic flowers. The family contains about 14,200 species in about 615 genera, which makes it the fourth-largest angiosperm family by number of species. Rubiaceae has a cosmopolitan distribution; however, the largest species diversity is concentrated in the tropics and subtropics. Economically important genera include  Coffea, the source of coffee; Cinchona, the source of the antimalarial alkaloid quinine; ornamental cultivars (e.g., Gardenia, Ixora, Pentas); and historically some dye plants (e.g., Rubia).
Siege of Tauromenium (394 BC)
The siege of Tauromenium was laid down by Dionysius, tyrant of Syracuse, in the winter of 394 BC, in the course of the Sicilian Wars against Carthage. After defeating the Carthaginians at the Battle of Syracuse in 397 BC, Dionysius had been expanding his territory and political influence by conquering Sicel lands and planting Greek colonies in northeastern Sicily. Tauromenium was a Sicel city allied to Carthage and in a position to threaten both Syracuse and Messina. Dionysius laid siege to the city in the winter of 394 BC, but had to lift the siege after his night assault was defeated. Carthage responded to this attack on their allies by renewing the war, which was ended by a peace treaty in 392 BC that granted Dionysius overlordship of the Sicels, while Carthage retained all territory west of the Halykos and Himera rivers in Sicily.

Sicels
The Sicels (/ˈsɪkəlz, ˈsɪsəlz/ SIK-əlz, SISS-əlz; Latin: Sicelī or Siculī) were an Indo-European tribe who inhabited eastern Sicily, their namesake, during the Iron Age. They spoke the Siculian language. After the defeat of the Sicels at the Battle of Nomae in 450 BC and the death of Sicel leader Ducetius in 440 BC, the Sicel state broke down and the Sicel culture merged into Magna Graecia.
Grgelj
Grgelj (pronounced [ˈɡəɾɡəl]; German: Beim Gergel, Beim Görgel) is a dispersed settlement that stretches along the left bank of the Kolpa River in the Municipality of Kostel in southern Slovenia. The area is part of the traditional region of Lower Carniola and is now included in the Southeast Slovenia Statistical Region.

Kupa
The Kupa (Croatian pronunciation: [kûpa]) or Kolpa (Slovene pronunciation: [ˈkóːlpa] or [ˈkóːwpa]; from Latin: Colapis in Roman times; Hungarian: Kulpa) river, a right tributary of the Sava, forms a natural border between north-west Croatia and southeast Slovenia. It is 297 kilometres (185 miles) long, with a length of 118 km (73 mi) serving as the border between Croatia and Slovenia and the rest located in Croatia.
Georgian International Academy
Georgian International Academy (Georgian: საქართველოს საერთაშორისო აკადემია) is a private institution located in Isani-Samgori District, Tbilisi, Georgia. The academy is one of the few Georgian institutions which awards the degree “Doctor Academician”.

Georgian International Academy also operates a junior college – a two-year post-secondary school whose main purpose is to provide academic, vocational and professional education.

Junior college
A junior college is a type of post-secondary institution that offers vocational and academic training that is designed to prepare students for either skilled trades and technical occupations or support roles in professions such as engineering, accountancy, business administration, nursing, medicine, architecture, and criminology. Often times, those types of colleges offer two-year associate's degrees that are intended for students that want to later transfer to a college for a four-year bachelor's degree to finish their undergraduate education, pending adequate grades. Students typically attend those types of colleges for one to three years, which is also dependent on the country.
Players Tour Championship 2015/2016
The Players Tour Championship 2015/2016 was a series of snooker tournaments which started on 29 July 2015 and ended on 27 March 2016, with events held across Europe and Asia. In this season the European events form the European Tour and events held in Asia the Asian Tour. This season there were seven regular minor-ranking events down from nine the previous season concluding with the finals which held full Ranking event status.

Players Tour Championship
The Players Tour Championship was a series of snooker tournaments comprising some minor-ranking events played in Europe, and an Asian leg comprising some minor-ranking events in Asia. The series concluded with a Grand Final, where qualification was based on performance in the other PTC events, and had the status of a full ranking tournament. Each regular event lasted for at least three days, with qualifying days for amateurs should the event be oversubscribed. Each event costs £100 to enter, and Main Tour players can gain ranking points in the events.
Xanthorrhoea thorntonii
Xanthorrhoea thorntonii, commonly known as Cundeelee grasstree, Cundeelee blackboy, desert grasstree, yacka  or grasstree, is a species of grasstree of the genus Xanthorrhoea native to central Australia. It is known to the Pitjantjatjara people as kata-kultu, kata-puru, ulpa or urara, the Warlpiri people as yurlurnkuru and the Arrernte as lunkere. X. thorntonii is the only grass tree found in Central Australia including the Great Sandy Desert, Great Victoria Desert and MacDonnell Ranges.

Arrernte people
The Arrernte (/ˈʌrəndə/) people, (also Aranda, Arunta or Arrarnta), are a group of Aboriginal Australian peoples who live in the Arrernte lands, at Mparntwe (Alice Springs) and surrounding areas of the Central Australia region of the Northern Territory. Many still speak one of the various Arrernte dialects. Some Arrernte live in other areas far from their homeland, including the major Australian cities and overseas.

Arrernte spirituality focuses on the landscape and The Dreaming which the Arrernte name for is Altyerre. Altjira is the creator being of the Inapertwa that became all living creatures. Tjurunga are objects of religious significance.

The Arrernte Council is the representative and administrative body for the Arrernte Lands and is part of the Central Land Council.

Tourism is important to the economy of Alice Springs and surrounding communities.
DubaiSat-1
DubaiSat-1 (Arabic: دبي سات-1) is a remote sensing Earth observation satellite built by the Mohammed bin Rashid Space Centre (MBRSC) under an agreement with Satrec Initiative, a satellite manufacturing company in South Korea.

DubaiSat-1 was launched on 29 July 2009 into a 680 km altitude Sun-synchronous polar orbit from the Baikonur launch site in Kazakhstan, along with several other satellites on board the Dnepr launch vehicle.

Sun-synchronous orbit
A Sun-synchronous orbit (SSO), also called a heliosynchronous orbit, is a nearly polar orbit around a planet, in which the satellite passes over any given point of the planet's surface at the same local mean solar time. More technically, it is an orbit arranged so that it precesses through one complete revolution each year, so it always maintains the same relationship with the Sun.
Bargteheide-Land
Bargteheide-Land is an Amt ("collective municipality") in the district of Stormarn, in Schleswig-Holstein, Germany. It is situated around Bargteheide, which is the seat of the Amt, but not part of it.

The Amt Bargteheide-Land consists of the following municipalities:

Bargfeld-Stegen

Delingsdorf

Elmenhorst

Hammoor

Jersbek

Nienwohld

Todendorf

Tremsbüttel

Bargteheide
Bargteheide (German pronunciation: [baʁktəˈhaɪdə] ⓘ; Low German: Bartheil) is a town in the district of Stormarn, Schleswig-Holstein state, Germany. It is situated between the cities of Ahrensburg and Bad Oldesloe, on the Hamburg to Lübeck rail line and is part of the Hamburg Metropolitan Region.

The population of Bargteheide was 16,045 at the end of 2017.
Rovde Church
Rovde Church (Norwegian: Rovde kyrkje) is a parish church of the Church of Norway in Vanylven Municipality in Møre og Romsdal county, Norway. It is located in the village of Rovdane, along the Rovdefjorden. It is the church for the Rovde parish which is part of the Søre Sunnmøre prosti (deanery) in the Diocese of Møre. The white, wooden church was built in a long church design in 1872 using plans drawn up by the architect Lars Tornæs from Ålesund. The church seats about 350 people.

Møre og Romsdal
Møre og Romsdal (Urban East Norwegian: [ˈmø̂ːrə ɔ ˈrʊ̀msdɑːɫ] ⓘ; English: Møre and Romsdal) is a county in the northernmost part of Western Norway. It borders the counties of Trøndelag, Innlandet, and Vestland. The county administration is located in the town of Molde, while Ålesund is the largest town. The county is governed by the Møre og Romsdal County Municipality which includes an elected county council and a county mayor. The national government is represented by the county governor.
Dushyant Chaturvedi
Dushyant Chaturvedi (Marathi: दुष्यंत चतुर्वेदी) is a Shiv Sena politician from Nagpur, Maharashtra. He is current Member of Legislative Council from Yavatmal local authorities constituency. He is the son of former Congress minister Satish Chaturvedi.

Yavatmal
Yavatmal (pronunciationⓘ) is a city and municipal council in the Indian state of Maharashtra. It is the administrative headquarters of Yavatmal District. Yavatmal is around 90 km away from divisional headquarters Amravati while it is 670 km (420 mi) away from the state capital Mumbai and 150 km south west of Nagpur.
106th Division (Imperial Japanese Army)
The 106th Division (第106師団, Dai-hyakuroku Shidan) was an infantry division of the Imperial Japanese Army. It has no call sign, similar to 101st division. It was formed 15 May 1938 in Kumamoto as a C-class square division. The nucleus for the formation was the 6th division headquarters. The division was originally subordinated to the Central China Expeditionary Army. Its first division commander was Lieutenant General Matsuura Junrokuro, a graduate from Japanese Army War College.

Kumamoto
Kumamoto (熊本市, Kumamoto-shi; Japanese pronunciation: [kɯ.ma.mo.to, -toꜜ.ɕi]) is the capital city of Kumamoto Prefecture on the island of Kyushu, Japan. As of June 1, 2019, the city has an estimated population of 738,907 and a population density of 1,893 people per km2. The total area is 390.32 km2.

Greater Kumamoto (熊本都市圏) had a population of 1,461,000, as of the 2000 census. As of 2010, Kumamoto Metropolitan Employment Area has a GDP of US$39.8 billion. It is not considered part of the Fukuoka–Kitakyushu metropolitan area, despite their shared border. The city was designated on April 1, 2012, by government ordinance.
A Love Letter to You 2
A Love Letter to You 2 (often abbreviated as ALLTY2) is the second commercial mixtape by American rapper Trippie Redd. It is also the second installment in the A Love Letter to You mixtape series. It was released on October 6, 2017, by TenThousand Projects and Caroline Distribution. It is the second release into Trippie Redd's A Love Letter to You series, of which began in May 2017. The album reached number 34 on the US Billboard 200. The mixtape featured guest appearances from Khalil, Cydnee with a C, Forever Anti Pop, Bali Baby, Chris King, UnoTheActivist and Rocket Da Goon.

Khalil (singer)
Khalil Amir Sharieff (born November 22, 1994) is an American R&B singer, songwriter, and rapper from Sacramento, California. At the age of 15, he was discovered by record executive Kawan Prather and signed to Island Def Jam in 2010. He released his debut single, "Girlfriend Ringtone", in May of that year and its follow up, "Hey Lil Mama" (featuring Lil Twist), the following year; the former lingered on the Bubbling Under Hot 100 chart. Due to their lack of commercial response, his album Hot Like Summer was shelved indefinitely. Khalil and Def Jam labelmate Justin Bieber were closely associated; Sharieff was an accomplice to Bieber's 2014 legal encounters and public mishaps.
C. V. L. Narasimha Rao
C. V. L. Narasimha Rao is an Indian character actor known for his works in Telugu cinema, theatre, television, and radio. Rao is one of the senior member, and legal advisor in the Movie Artist's Association of Hyderabad.

Telugu theatre
Telugu theatre is Indian theatre performed in the Telugu language, based in the states of Andhra Pradesh and Telangana. Gurajada Apparao wrote the play, Kanyasulkam in 1892, which is often considered the greatest play in the Telugu language. C. Pullaiah is cited as the father of Telugu theatre movement.

Vemuri Gaggaiah was an important member of the Mylavaram Bala Bharathi Nataka Samajam in Mylavaram, Krishna district during 1913–28. Through "Mylavaram Theatre", Gaggaiah became a household name for his mythological roles. Tirupati Venkata Kavulu have dramatised several of the Hindu epics into dramas and plays consisting of singable verses set to perfect meter. Several of their plays, especially pandavodyogavijayalu have been widely known among many drama clubs and audiences across Andhra Pradesh. The Nandi Natakotsavam Awards are awarded every year by the Government of Andhra Pradesh for achievements in Telugu theatre.
University of Pittsburgh at Johnstown
The University of Pittsburgh at Johnstown (UPJ or Pitt-Johnstown) is a state-related college in Richland Township, Cambria County, Pennsylvania, near the city of Johnstown. A baccalaureate degree-granting, regional campus of the University of Pittsburgh, UPJ was founded in 1927 as one of the first regional campuses of a major university in the United States.

Satellite campus
A satellite campus, branch campus, or regional campus is a campus of a university or college that is physically at a distance from the institution's main campus area. This branch campus may be located in a different location, city, state, or country, and is often smaller than the primary campus of an institution. A satellite campus may or may not share the same accreditation, administrative structures, budgets, resources, and governance as the main campus.
Fulgence Muteba Mugalu
Fulgence Muteba Mugalu (born 9 July 1962) is a Congolese Catholic prelate who serves as Archbishop of the Roman Catholic Archdiocese of Lubumbashi, in the Democratic Republic of the Congo, since 22 May 2021. Before that, from 18 March 2005	until 22 May 2021, he was Bishop of the Roman Catholic Diocese of Kilwa-Kasenga in the DR Congo. He was appointed bishop on 18 March 2005 by Pope Benedict XVI. He was consecrated and installed at Kilwa on 23 July 2005. He concurrently served as the Apostolic Administrator of the Catholic Diocese of Kamina from 3 December 2020 until 2 February 2024 and as Apostolic Administrator of Kilwa-Kasenga Diocese from 22 May 2021 until 10 July 2021.

Apostolic administration
An apostolic administration in the Catholic Church is administrated by a prelate appointed by the pope to serve as the ordinary for a specific area. Either the area is not yet a diocese (a stable 'pre-diocesan', usually missionary apostolic administration), or is a diocese, archdiocese, eparchy or similar permanent ordinariate (such as a territorial prelature or a territorial abbacy) that has no mainstay prelate (an apostolic administrator sede vacante, as after an episcopal death, resignation or transfer to another territory) or, in very rare cases, has an incapacitated head (apostolic administrator sede plena). The title also applies to an outgoing incumbent while awaiting for the date of assuming his new position or date of effectivity of a retirement.
2018 Pekao Szczecin Open – Doubles
Wesley Koolhof and Artem Sitak were the defending champions but chose not to defend their title.

Karol Drzewiecki and Filip Polášek won the title after defeating Guido Andreozzi and Guillermo Durán 6–3, 6–4 in the final.

Artem Sitak
Artem Yurievich Sitak (/ˈɑːrtəm ˈsɪtæk/ ART-əm SIT-ak; Russian: Артём Юрьевич Ситак, romanized: Artyom Sitak; born 8 February 1986) is a Russian-born New Zealand former professional tennis player. On 11 August 2008, he reached his highest ATP singles ranking of World No. 299, whilst his highest doubles ranking of World No. 32 was reached on 10 September 2018, after the US Open. He is the younger brother of Dmitri Sitak, who was also a professional tennis player.
P-site
The P-site (for peptidyl) is the second binding site for tRNA in the ribosome.  The other two sites are the A-site (aminoacyl), which is the first binding site in the ribosome, and the E-site (exit), the third. During protein translation, the P-site holds the tRNA which is linked to the growing polypeptide chain. When a stop codon is reached, the peptidyl-tRNA bond of the tRNA located in the P-site is cleaved releasing the newly synthesized protein. During the translocation step of the elongation phase, the mRNA is advanced by one codon, coupled to movement of the tRNAs from the ribosomal A to P and P to E sites, catalyzed by elongation factor EF-G.

Stop codon
In molecular biology, a stop codon (or termination codon) is a codon (nucleotide triplet within messenger RNA) that signals the termination of the translation process of the current protein. Most codons in messenger RNA correspond to the addition of an amino acid to a growing polypeptide chain, which may ultimately become a protein; stop codons signal the termination of this process by binding release factors, which cause the ribosomal subunits to disassociate, releasing the amino acid chain.

While start codons need nearby sequences or initiation factors to start translation, a stop codon alone is sufficient to initiate termination.
Tami Neilson
Tamara "Tami" Neilson is a Canadian-born New Zealand country & soul singer/songwriter. She is the winner of multiple awards, including the 2014 APRA Silver Scroll Awards and Best Country Song Award; she is also the winner of the Best Country Album at the New Zealand Music Awards in 2009, 2010, 2012, and 2015, and Best Female Artist at the New Zealand Country Music Awards in 2010, 2011, and 2014.

APRA Awards (New Zealand)
The APRA Music Awards are several annual and two-yearly award ceremonies run in New Zealand by Australasian Performing Right Association to recognise songwriting skills of its members. APRA hold the annual Silver Scroll Awards and song awards, selects an inductee into the New Zealand Music Hall of Fame, and makes five professional development awards every year. APRA also runs awards for its Australian members.
Code Red DVD
Code Red DVD was an independent American home entertainment company specializing in retro exploitation and horror films, operated by Bill Norton Olsen. The company originally began releasing films on DVD in 2006, and later began releasing and re-releasing titles on Blu-ray.

Exploitation film
An exploitation film is a film that seeks commercial success by capitalizing on current trends, niche genres, or sensational content. Exploitation films often feature themes such as suggestive or explicit sex, sensational violence, drug use, nudity, gore, destruction, rebellion, mayhem, and the bizarre. While often associated with low-budget "B movies", some exploitation films have influenced popular culture, attracted critical attention, gained historical significance, and developed cult followings.