hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
PF-610355
PF-610355 (also known as PF-00610355 or PF-610,355) is an inhalable ultra-long-acting β2 adrenoreceptor agonist (ultra-LABA) that was investigated as a treatment of asthma and COPD by Pfizer. It utilizes a sulfonamide agonist headgroup, that confers high levels of intrinsic crystallinity that could relate to the acidic sulfonamide motif supporting a zwitterionic form in the solid state. Optimization of pharmacokinetic properties minimized systemic exposure following inhalation and reduced systemically mediated adverse events. Its in vivo duration on action confirmed its potential for once-daily use in humans.

The investigation and development of PF-610355 were discontinued in 2011, likely for strategic and regulatory reasons.

Pharmacokinetics
Pharmacokinetics (from Ancient Greek pharmakon 'drug' and kinetikos 'moving, putting in motion'; see chemical kinetics), sometimes abbreviated as PK, is a branch of pharmacology dedicated to describing how the body affects a specific substance after administration. The substances of interest include any chemical xenobiotics such as pharmaceutical drugs, pesticides, food additives, cosmetics, etc. PK attempts to analyze chemical metabolism and discover the fate of a chemical from the moment that it is administered up to the point at which it is completely eliminated from the body. PK is based on mathematical modeling that places great emphasis on the relationship between drug plasma concentration and the time elapsed since the drug's administration. Pharmacokinetics is the study of how an organism affects the drug, whereas pharmacodynamics (PD) is the study of how the drug affects the organism. Both together influence dosing, benefit, and adverse effects, as seen in PK/PD models.
Agnes G. Doody
Agnes Grace Doody, Ph.D. (April 12, 1930 – April 28, 2023) was an academic primarily in the field of speech communication and faculty member for 45 years at the University of Rhode Island. She was engaged in philanthropy and civic engagement locally and around the State of Rhode Island.

South Kingstown, Rhode Island
South Kingstown is a town in, and the county seat of, Washington County, Rhode Island, United States. The population was 31,931 at the 2020 census. South Kingstown is the second largest town in Rhode Island by total geographic area, behind New Shoreham, and the third largest town in Rhode Island by geographic land area, behind Exeter and Coventry.
Krzysztof Jurgiel
Krzysztof Jurgiel (born 18 November 1953, in Ogrodniki) is a Polish politician. He is the former Minister of Agriculture and Rural Development in the cabinet of Beata Szydło (from 16 November 2015 to 2018).

Cabinet of Beata Szydło
Cabinet of Beata Szydło formed the 17th government of Poland, until 11 December 2017. Governing during the 8th legislature of the Sejm and the 9th legislature of the Senate, it was led by Beata Szydło.

On 7 April 2017 the government survived a motion of no confidence entered by the opposition, which was rejected with 174 ayes, 238 nays and four abstentions.
Anangu Schools
Anungu schools is a group of ten schools operated by the Government of South Australia which are located in the west of the Australian state of South Australia. Eight are located in the Aboriginal lands of Anangu Pitjantjatjara Yankunytjatjara (APY lands), while one is in Maralinga Tjarutja and  on in the community of Yalata, all offering primary and secondary schooling to a local body of students who are largely Aboriginal.

The word anangu means "human being", or "person", and is used by several Aboriginal Australian peoples of the Western Desert cultural bloc to describe themselves.

Western Desert cultural bloc
The Western Desert cultural bloc (also capitalised, abbreviated to WDCB, or just Western Desert) is a cultural region in central Australia covering about 600,000 square kilometres (230,000 mi2), used to describe a group of linguistically and culturally similar Aboriginal Australian nations.
Ambrosio Martínez Bustos
Ambrosio Martínez Bustos (1614-1672) was a Spanish Baroque painter active in Granada.

Born in and resident of Granada, Martínez Bustos was from a wealthy family, and was trained in the studio of Miguel Jerónimo de Cieza. According to his marriage certificate he married on February 8, 1635. Cieza's workshop was one of the busiest and most prestigious in Granada. He was initially influenced by Flemish painting through known prints, as seen in his Inmaculada  at the Museo de Bellas Artes de Granada. His specialty was the major theme of the Immaculate Conception, on which he produced several copies (church of St. Andrew, St. Cecilio and St. Scholastica, Museum of Fine Arts, Casa de los Tiros and others). He also is known to have collaborated with Pedro Atanasio Bocanegra and Cieza for the ephemeral decorations for the celebration of Corpus Christi.

Museo de Bellas Artes de Granada
The Museo de Bellas Artes de Granada (Museum of Fine Arts of Granada ) is a fine arts museum in Granada, Spain. Since the 1950s it has been housed in the Palace of Charles V which also houses the Museo de la Alhambra.
Coach of the Year (ice hockey)
The Swedish Ice Hockey Coach of the Year (Swedish: Årets Coach) has been awarded to the best ice hockey coach in Sweden each season since the 1991–92 season. The award was created in honor of Arne Strömberg, and Kamratföreningen Hockeyjournalisterna is the jury which votes on the award. The award has usually gone to a coach in the top-tier league (SHL/Elitserien), although the award is not specific to the top-tier league.

Brynäs IF
Brynäs IF is a Swedish professional ice hockey team from Gävle. The club currently plays in the Swedish Hockey League (SHL), promoted from the HockeyAllsvenskan, the second tier of ice hockey in Sweden, following the 2023–24 season. The club played in the top-tier Swedish league from 1960 to 2023 (1960-75 called Division I, 1975-2023 called the SHL), a total of 63 seasons, longer than any other Swedish club, before suffering relegation for the first time in franchise history at the conclusion of the 2022–23 season. They have won the Swedish championship 13 times, second only to Djurgården with 16 wins. In the 2023/2024 Hockeyallsvenskan season Brynäs won promotion back to the SHL after beating Djurgården 4-0 in the final.
Hermiston, Edinburgh
Hermiston is a hamlet formerly in the county of Midlothian and now part of Edinburgh, the capital of Scotland. It is north of Heriot-Watt University's Riccarton Campus and west of the Hermiston Gait commercial development. Hermiston is bounded by the A71 Calder Road to the south and the Union Canal to the north with the M8 motorway just beyond. A park and ride site serving western Edinburgh is located south-west of the A71 Calder Road roundabout.

The hamlet forms the Hermiston Conservation Area.

Hermiston is also notable as the setting of the Robert Louis Stevenson novel Weir of Hermiston. The city of Hermiston, Oregon in turn takes its name from the book.

Weir of Hermiston
Weir of Hermiston is an 1896 unfinished novel by Robert Louis Stevenson. It is markedly different from his previous works in style and has often been praised as a potential masterpiece. It was cut short by Stevenson's sudden death in 1894 from a cerebral haemorrhage. The novel is set at the time of the Napoleonic Wars.
Struum
Struum (stylized as struum) was an online streaming platform  headquartered in Los Angeles, California. The service focused on leveraging a credit-based subscription model that combines the content libraries from over 25 different streaming services.

Based on the ClassPass model, which allowed subscribers to use the facilities of any member health club, the service acted as an aggregator for various small specialty video-on-demand streaming applications, allowing subscribers to use monthly credits to view content from any of the participating services rather than having to individually subscribe to each app.

Its preview product was first launched in the United States on May 25, 2021, on various devices, including iOS mobile/tablet, web browsers, and Chromecast. The service would quietly shutter operations in February 2023 after running out of cash for its operations.

Video aggregator
A video aggregator is a website that collects and organizes online videos from other sources. Video aggregation is done for different purposes, and websites take different approaches to achieve their purpose.

Some sites try to collect videos of high quality or interest for visitors to view; the collection may be made by editors or may be based on community votes. Another method is to base the collection on those videos most viewed, either at the aggregator site or at various popular video hosting sites. Some other sites exist to allow users to collect their own sets of videos, for personal use as well as for browsing and viewing by others; these sites can develop online communities around video sharing. Still other sites allow users to create a personalized video playlist, for personal use as well as for browsing and viewing by others.
Morinari Watanabe
Morinari Watanabe (渡邊守成, Watanabe Morinari; born 21 February 1959) is a Japanese businessman who has served as president of the Fédération Internationale de Gymnastique since January 2017. Prior to his election in October 2016, he served as general-secretary of the Japan Gymnastics Association (2009–16) and was on multiple committees with the  Japanese Olympic Committee.

Watanabe is the ninth president of the FIG and its first Asian president. In October 2018, the International Olympic Committee elected him as a new member. He was also appointed an executive board member of Tokyo 2020. In September 2024, he was announced as one of seven candidates in the running to succeed Thomas Bach as IOC president. During the 144th IOC Session in March 2025, he got four votes, with Kirsty Coventry winning the election.

Thomas Bach
Thomas Bach (born 29 December 1953) is a German lawyer, former foil fencer, and Olympic gold medalist. He served as the ninth president of the International Olympic Committee from 2013 to 2025. He was the first ever Olympic champion to be elected to that position. Since 2025, he has served as Honorary President of the International Olympic Committee. Bach is also a former German individual foil champion as well as a team world champion, and former member of the German Olympic Sports Confederation's executive board.
HSC Champion Jet 3
HSC Champion Jet 3 is a catamaran ferry operated by Seajets. Launched in 1997, she was initially chartered out as a civilian ferry, then became the first large catamaran to enter military service when she was commissioned into the Royal Australian Navy as HMAS Jervis Bay from 1999 to 2001.

In 2002, the catamaran was sent to Europe on charter, operating with Italian company TRIS during that year, before being chartered by SpeedFerries for its Dover to Boulogne-sur-Mer service. Renamed HSC SpeedOne, she operated on this route until she was impounded by French authorities in late 2008, as the company had failed to pay taxes. SpeedFerries was placed into administration shortly after, and the ferry was laid up until 2010, when she was purchased by Condor Ferries and renamed Condor Rapide. She was then sold in 2021 to Trasmapi, a Spanish ferry operator. In August 2023, Greek ferry operator Seajets purchased the vessel and renamed it Champion Jet 3.

Sifnos
Sifnos (Greek: Σίφνος) is an island municipality in the Cyclades island group in Greece. The main town, near the center, known as Apollonia (pop. 918 as of 2021), is home of the island's folklore museum and library. The town's name is thought to come from an ancient temple of Apollo on the site of the church of Panayia Yeraniofora.  The second-largest town is Artemonas, thought to be named after an ancient temple of Apollo's sister Artemis, located at the site of the church of Panayia Kokhi.  The village of Kastro, was the capital of the island during ancient times until 1836. It is built on top of a high cliff on the island's east shore and today has extensive medieval remains and is the location of the island's archeological museum. The port settlement, on the west coast of the island is known as Kamares.
Nowy Olszowiec
Nowy Olszowiec [ˈnɔvɨ ɔlˈʂɔvjɛt͡s] is a village in the administrative district of Gmina Lubochnia, within Tomaszów Mazowiecki County, Łódź Voivodeship, in central Poland. It lies approximately 4 kilometres (2 mi) east of Lubochnia, 13 km (8 mi) north-east of Tomaszów Mazowiecki, and 48 km (30 mi) south-east of the regional capital Łódź.

Tomaszów Mazowiecki
Tomaszów Mazowiecki (pronounced [tɔˈmaʂuf mazɔˈvjɛt͡skʲi] ⓘ, Yiddish: טאָמעשעוו or Tomashuv) is a town in central Poland with 60,529 inhabitants (2021). It is the fourth most populous city in the Łódź Voivodeship and the second with free public transport. It is the seat of Tomaszów County.

In Tomaszów Mazowiecki there is the first (and the only) all-year speed skating track in Poland - Ice Arena Tomaszów Mazowiecki, which has hosted the World Championships. In autumn, the city hosts the international Love Polish Jazz festival, organized by the Polish Ministry of Culture and National Heritage.
Tương Dương district
Tương Dương is a rural district of Nghệ An province, in the North Central Coast region of Vietnam. As of 2019 the district had a population of 77,830. The district covers an area of 2,811.92 km2. The district capital lies at Thạch Giám township.

North Central Coast
Bắc Trung Bộ (literally North Central Region, and often translated as North Central Coast) is one of the geographic regions of Vietnam. It consists of six provinces in northern part of Central Vietnam: Thanh Hóa, Nghệ An, Hà Tĩnh, Quảng Bình, Quảng Trị, Huế. The last two provinces were the northernmost provinces of State of Vietnam and South Vietnam until Reunification of Vietnam in 1976. In the Nguyễn dynasty, this area (except Thừa Thiên) was known as Hữu Trực Kỳ (the area located in the left of Thừa Thiên).
John Dart (bishop)
John Dart (1837–1910) was the second Bishop of New Westminster. Dart was educated at St Mary Hall, Oxford and ordained in 1861. During his career he was Vice-Principal and Science Lecturer at St Peter's College, Peterborough; Warden of St Thomas's College, Colombo; President of the University of Windsor; and a Canon of Halifax Cathedral.

Warden (college)
Warden is a title used by the heads of some university colleges, halls of residence, and other institutions. Its use in this sense dates back at least to the 13th century at Merton College, Oxford, as a translation of the Latin custos.
Li Shucheng
Li Shucheng (Chinese: 李書城; 1882–1965) was a senior leader of Kuomintang, and a politician of the People's Republic of China.

In 1921, the first National Congress of the Chinese Communist Party was held in his house in Shanghai, thus the CCP was founded with his brother Li Hanjun.

After the establishment of the People's Republic of China, Li served as the first Minister of Agriculture of PRC.

Ministry of Agriculture (China)
The Ministry of Agriculture (MOA) was a cabinet-level executive department of the State Council which was responsible for agriculture in China.

Areas of the ministry's responsibility included agriculture and environmental issues relating to agriculture, fishery, consumer affairs, animal husbandry, horticulture, animal welfare, foodstuffs, hunting and game management as well as higher education and research in the field of agricultural sciences. The ministry was headquartered in Beijing.

The ministry was abolished in 2018, with its responsibilities being assumed by the newly created Ministry of Agriculture and Rural Affairs on March 19, 2018.
St Stephen's Church, Little Ilford
St Stephen's Church, Little Ilford is the Roman Catholic parish church for Little Ilford and Manor Park, two areas in Newham, east London. It was first built in 1924 as a chapel to St Nicholas', Manor Park. St Stephen's was rebuilt in 1959 and became the parish church, with St Nicholas' as its chapel, the status both churches still hold today.

Manor Park, London
Manor Park is a residential area of the London Borough of Newham in east London, England. The area is bordered by Ilford to the east, Forest Gate to the west, Wanstead to the north, and East Ham to the south.

It was originally a part of the hundred of Becontree, and part of the historic county of Essex. Since 1965, Manor Park has been part of the London Borough of Newham, a local government district of Greater London.  The area forms the majority of the London E12 postcode district.
Rory O'Brien
Rory O'Brien (born 2 June 1989) is an Australian former professional rugby league footballer who played in the 2000s and 2010s. He most recently played for the Parramatta Eels in the National Rugby League, as a prop. He previously played for the St. George Illawarra Dragons.

Gold Coast Titans
The Gold Coast Titans are a professional rugby league football club, based on the Gold Coast, Queensland, Australia. The club competes in the National Rugby League (NRL) premiership, Australia's elite rugby league competition. Since 2008, the Titans have played their home games at Robina Stadium in Robina. The Titans joined the NRL in 2007.

The Gold Coast Titans were the first national-level franchise from the Gold Coast region since the previous franchise, the Gold Coast-Tweed Giants / Gold Coast Seagulls / Gold Coast Chargers, which existed from 1988 to 1998.
2022 Cook Islands general election
The 2022 Cook Islands general election was held on 1 August 2022 to determine the composition of the 18th Parliament of the Cook Islands. A referendum on legalising medical cannabis was held on the same day.

Titikaveka (electorate)
Titikaveka is a Cook Islands electoral division returning one member to the Cook Islands Parliament.

The electorate was created in 1981, when the Constitution Amendment (No. 9) Act 1980–1981 adjusted electorate boundaries and split the electorate of Takitumu into three. It consists of the tapere of Tikioki, Akapuao, Te Puna, Titikaveka, Kauare, Arakuo, Turoa, Totokoitu, Avaavaroa, and Vaimaanga on the island of Rarotonga.
Armorial of Albania
Heraldry, as a scholarly discipline that deals with the study and origin of various symbols and elements, emerged in Albania towards the end of the 13th century. Over time, it evolved as an inseparable component of European heraldry, encompassing its advancements, shifts and accomplishments.

The earliest evidence in the usage of coats of arms can be traced to the formative period of the Principality of Arbanon, with the Gropa ruling family. This practice continued in uninterrupted succession across various medieval Albanian lineages and patronymic families, namely the Albani, Angeli, Arianiti, Balsa, Becichemo, Dukagjini, Durazzo, Dusmani, Kastrioti, Matranga, Muzaka, Scura, Thopia and numerous others.

Marin Beçikemi
Marino Becichemo or Marin Beçikemi (c. 1468 – 1526) was an Albanian scholar and orator who was a prominent humanist in the cities of Brescia and later Padua in the Republic of Venice in the early 16th century. He maintained a humanist school and was a professor in the University of Padua. He wrote commentaries about classical Latin literature and was well known for his orations in the region of Venice.
École Émile-Cohl
École Émile-Cohl is a French art school. It is a private higher education institution recognized by the state and specialized in teaching drawing and illustration, animation film, video games, multimedia computer graphics, comics and press drawing.

Art school
An art school is an educational institution with a primary focus on practice and related theory in the visual arts and design. This includes fine art – especially illustration, painting, contemporary art, sculpture, and graphic design.   They may be independent or operate within a larger institution, such as a university. Some may be associated with an art museum.

Art schools may be organized to offer elementary, secondary, post-secondary, undergraduate, or graduate programs, and can also offer a broad-based range of programs (such as the liberal arts and sciences). In the West there have been six major periods of art school curricula, and each one has had its own hand in developing modern institutions worldwide throughout all levels of education. Art schools also teach a variety of non-academic skills to many students.
Nellie Ibbott
Nellie Grace Ibbott MBE (20 June 1889 in Leyton, Essex, England – 25 June 1970 in Mornington, Victoria, Australia) was a British-born Australian mayor. When Ibbott became mayor of the City of Heidelberg in 1943, she became the first woman in Victoria to hold mayoral office. In 1950 she was defeated at the council elections after serving for 22 years. Ibbott was awarded the MBE in 1954 "For service to local government and to charities".

Mornington, Victoria
Mornington is a seaside suburb of Melbourne, Victoria, Australia located on the Mornington Peninsula 46 km (29 mi) south-east of Melbourne's Central Business District. It is the most populous locality in the Shire of Mornington Peninsula local government area. Mornington had a population of 25,759 at the 2021 census.

Mornington is a tourist destination renowned for its bay beaches and wineries, with a town centre that runs into the foreshore area and local beach.
Lilaeopsis schaffneriana
Lilaeopsis schaffneriana is a rare species of flowering plant in the family Apiaceae known by the common names Schaffner's grasswort and cienega false rush.

Lilaeopsis schaffneriana subsp. schaffneriana is found in Dominican Republic, Ecuador, and Mexico (in the Federal District and the following states: Chihuahua, Coahuila, Durango, Hidalgo, Jalisco, México, Michoacán, Nuevo León, Oaxaca, Puebla, San Luis Potosí, and Tlaxcala).

Lilaeopsis schaffneriana subsp. recurva (Huachuca water umbel), is a federally listed endangered species (status G4T2, imperiled) of the United States. It is limited to desert wetlands, including a rare type of desert marsh habitat called a cienega. There are 8 populations in Arizona and four more south of the border in Mexico.

San Luis Potosí
San Luis Potosí, officially the Free and Sovereign State of San Luis Potosí, is one of the 32 states which compose the Federal Entities of Mexico. It is divided in 59 municipalities and is named after its capital city, San Luis Potosí.

It is located in eastern and central Mexico and is bordered by seven other Mexican states: Nuevo León to the north; Tamaulipas to the north-east; Veracruz to the east; Hidalgo, Querétaro and Guanajuato to the south; and Zacatecas to the north-west. In addition to the capital city, other major cities in the state include Ciudad Valles, Matehuala, Rioverde, and Tamazunchale.
Journal de St.-Pétersbourg
The Journal de St.-Pétersbourg or Journal de Saint-Pétersbourg was a French-language newspaper, published in Saint Petersburg, Russia, with varying periodicity and some interruptions, from 1825 to 1914. For at least some of this period it was an official or semi-official organ of the Russian Foreign Ministry.

Ministry of Foreign Affairs (Russia)
The Ministry of Foreign Affairs of the Russian Federation (MFA Russia; Russian: Министерство иностранных дел Российской Федерации, МИД России, romanized: Ministerstvo inostrannykh del Rossiiskoi Federatsii. MID Rossii) is the central government institution charged with leading the foreign policy and foreign relations of Russia.

It is a continuation of the Ministry of Foreign Affairs of the Russian Soviet Federative Socialist Republic, which was under the supervision of the Soviet Ministry of External Relations. Sergei Lavrov is the current foreign minister.
Joseph Hogarth
Joseph Hogarth (1801-1879) was a British fine art print publisher, print seller, frame maker and art restorer. He operated from various locations in central London in the middle decades of the nineteenth century. He was working in the field by 1826 and the business continued to operate till 1890, by which time it  was under the direction of his two sons.

Picture frame
A picture frame is a protective and decorative edging for a picture, such as a painting or photograph. It makes displaying the work safer and easier and both sets the picture apart from its surroundings and aesthetically integrates it with them.