hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
22R-Hydroxycholesterol
22R-Hydroxycholesterol, or (3β)-cholest-5-ene-3,22-diol is an endogenous, metabolic intermediate in the biosynthesis of the steroid hormones from cholesterol. Cholesterol ((3β)-cholest-5-en-3-ol) is hydroxylated by cholesterol side-chain cleavage enzyme (P450scc) to form 22R-hydroxycholesterol, which is subsequently hydroxylated again by P450scc to form 20α,22R-dihydroxycholesterol, and finally the bond between carbons 20 and 22 is cleaved by P450scc to form pregnenolone ((3β)-3-hydroxypregn-5-en-20-one), the precursor to the steroid hormones.

It is an agonist of the liver X receptor.

Metabolic intermediate
Metabolic intermediates are compounds produced during the conversion of substrates (starting molecules) into final products in biochemical reactions within cells.

Although these intermediates are of relatively minor direct importance to cellular function, they can play important roles in the allosteric regulation of enzymes, glycolysis, the citric acid cycle, and amino acid synthesis.

Metabolic pathways consist of a series of enzymatically catalyzed reactions where each step transforms a substrate into a product that serves as the substrate for the next reaction. Metabolic intermediates are compounds that form during these steps, and they are neither the starting substrate nor the final product of the pathway. These intermediates are crucial because they allow for regulation, energy storage, and extraction of chemical energy in a controlled manner.
Nickson Kolo
Nickson Kolo is a Papua New Guinean professional rugby league footballer, a blockbusting forward who plays for the newly formed club Gulf Isapeas in the Digicel Cup in Papua New Guinea, He is a former Papua New Guinea international.

He has represented Papua New Guinea in the Prime Minister's XIII games between Australia and PNG between 2007 and 2010.
His trade mark, blockbusting runs had earned him a place in the Papua New Guinea training squad for the 2008 Rugby League World Cup.

He played for PNG  in the 2008 Rugby League World Cup.

He has also played for Papua New Guinea in the 2010 Four Nations tournament in New Zealand and Australia.

Prime Minister's XIII
Prime Minister's XIII, sometimes informally referred to as the PM's XIII, are a representative rugby league team, comprising Australian players from National Rugby League clubs. Initially, the team was selected from NRL clubs that did not qualify for the NRL finals. Over time this changed to include players whose teams were knocked out during the first two weeks of the finals, with the game played on the same weekend as the preliminary finals, one week prior to the NRL Grand Final. Since 2024, the Prime Minister's XIII game has been played on the weekend after the NRL Grand Final, with players from all clubs, including the Grand Finalists, available for selection.
Snohomish County Centennial Trail
The Snohomish County Centennial Trail is a 30-mile-long (48 km) rail trail in Snohomish County, Washington, connecting the cities of Snohomish, Lake Stevens, and Arlington to Skagit County along the corridor of Washington State Route 9. The trail, administered by Snohomish County Parks and Recreation, is on the former right-of-way of the Seattle, Lake Shore and Eastern Railway and comprises a 10-foot-wide (3.0 m) non-motorized trail and a 6-foot-wide (1.8 m) equestrian trail. The first segment of the corridor was opened in 1989, the centennial of the statehood of Washington, and the final segment between Arlington and the Skagit County line was opened in 2013.

Stillaguamish River
The Stillaguamish River is a river in the northwestern region of the U.S. state of Washington. It is mainly composed of two forks, the longer North Fork Stillaguamish (45 miles (72 km)) and the South Fork Stillaguamish.  The two forks join near Arlington. From there the Stillaguamish River proper flows for 22 miles (35 km) to Puget Sound.  The river's watershed drains part of the Cascade Range north of Seattle.
Paul Jeacock
Paul Anthony Jeacock (born 25 April 1963) is a former English cricketer.  Jeacock was a right-handed batsman who bowled right-arm off break.  He was born in Bicester, Oxfordshire.

Jeacock made his debut for Oxfordshire in the 1998 MCCA Knockout Trophy against Huntingdonshire.  Jeacock played Minor counties cricket for Oxfordshire from 1998 to 2004, which included 14 Minor Counties Championship matches and 16 MCCA Knockout Trophy matches. He made his List A debut against the Durham Cricket Board in the 1999 NatWest Trophy.  He played 3 further List A matches, the last coming against Shropshire in the 2nd round of the 2002 Cheltenham & Gloucester Trophy which was held in 2001. In his 4 List A matches he took 3 wickets at a bowling average of 41.00, with best figures of 2/23.

Durham Cricket Board
The Durham Cricket Board is the governing body for all recreational cricket in the historic county of Durham.

From 1999 to 2003, the Board fielded a team in the English domestic one-day tournament, matches which had List-A status.
Juniperic acid
Juniperic acid or 16-hydroxyhexadecanoic acid is an omega-hydroxy long-chain fatty acid that is palmitic acid which is substituted at position 16 by a hydroxy group. Palmitic acid is converted to juniperic acid by cytochrome P450 various enzymes, including CYP704B22.

Juniperic acid is a key monomer of cutin in the plant cuticle.  It has a role as a plant metabolite.

Hydroxy group
In chemistry, a hydroxy or hydroxyl group is a functional group with the chemical formula −OH and composed of one oxygen atom covalently bonded to one hydrogen atom. In organic chemistry, alcohols and carboxylic acids contain one or more hydroxy groups. Both the negatively charged anion HO−, called hydroxide, and the neutral radical HO·, known as the hydroxyl radical, consist of an unbonded hydroxy group.

According to IUPAC definitions, the term hydroxyl refers to the hydroxyl radical (·OH) only, while the functional group −OH is called a hydroxy group.
The Great White Hype (soundtrack)
Music from the Motion Picture: The Great White Hype is the soundtrack to Reginald Hudlin's 1996 film The Great White Hype. It was released in April 1996 through Epic Soundtrax, and consists primarily of hip hop music. Composed of thirteen songs, it features appearances by the likes of Ambersunshower, Biz Markie, Bone Thugs-n-Harmony, Camp Lo, DJ U-Neek, E-40, Insane Clown Posse, Jamie Foxx, Lou Rawls, Marcus Miller, Nyt Owl, Passion, Premier, Rudy Ray Moore, and Wu-Tang Clan members. Production was handled by DJ U-Neek, Marcus Miller, RZA, 4th Disciple, Doug Rasheed, Foster & McElroy, ICP, Jocko, Mike E. Clark, P.M. Dawn, Ski Beatz and Studio Ton.

The album peaked at number 93 on the Billboard 200, number 27 on the Top R&B/Hip-Hop Albums in the United States. Its lead single, Camp Lo's "Coolie High", peaked at #62 on the Hot R&B/Hip-Hop Songs and #25 on the Hot Rap Songs.

4th Disciple
Selwyn Bougard, now known as El-Divine Amir Bey (born May 23, 1974), better known by his stage name 4th Disciple, is a DJ, record producer and audio engineer who was one of the founding members of Killarmy and one of the best-known Wu-Tang-affiliated producers. He is the only member of the Wu Elements to have worked on Wu-Tang Clan's first breakthrough album, as a mixer.
Robert Hoapili Baker
Robert Hoapili Kekaipukaʻala Baker (c. 1845/1847 – April 4, 1900) was a Hawaiian ali'i (noble), military officer, courtier, and politician who served many political posts in the Kingdom of Hawaii, including Governor of Maui, Privy Councillor and aide-de-camp to King Kalākaua.

Courtier
A courtier (/ˈkɔːrtiər/) is a person who attends the royal court of a monarch or other royalty. The earliest historical examples of courtiers were part of the retinues of rulers. Historically, the court was the centre of government as well as the official residence of the monarch, and the social and political life were often completely mixed together.
Subepithelial connective tissue graft
Recipient site exhibits gingival recession on both premolars and first molar (molar recession is not an esthetic issue and will not be treated)

Incisions prior to flap reflection

Full thickness flap elevated

Another viewpoint of the flapped recipient site

In dentistry, the subepithelial connective tissue graft (SECT graft, and sometimes referred to simply as a connective tissue (CT) graft) is an oral and maxillofacial surgical procedure first described by Alan Edel in 1974.  Currently, it is generally used to obtain root coverage following gingival recession, which was a later development by Burt Langer in the early 1980s.

Glossary of dentistry
This is a list of definitions of commonly used terms of location and direction in dentistry. This set of terms provides orientation within the oral cavity, much as anatomical terms of location provide orientation throughout the body.
Diocese of Kilwa–Kasenga
The Roman Catholic Diocese of Kilwa–Kasenga (Latin: Kilvaën(sis) – Kasengaën(sis)) is a diocese located in the cities of Kilwa and Kasenga  in the ecclesiastical province of Lubumbashi in the Democratic Republic of the Congo.

Kasenga
Kasenga is a town in  Kasenga territory of Haut-Katanga province of the Democratic Republic of the Congo.  It is located in south of Lake Mweru, approximately 135 miles (217 km) north-east of Lubumbashi., near the border with Zambia.
Bahiya Al Aradi
Bahiya Al Aradi  (Arabic: بهیة العرادی) (? – 16 March 2011) was the first woman killed in the Bahraini Uprising. She has been called a shaheeda, or female martyr, by her family.

On March 16, the government allowed her brother to visit her for a few minutes in Bahrain Defense Force Hospital (Bahrain Royal Medical Services).

She died on hospital from injuries she received when she was hit in the back by birdshot pellets fired from a range of 50 to 75 meters.
On March 20, the hospital announced that she had died of her injuries. At least one bullet had entered al-Aradi's head from behind. There was no exit wound.

Bahrain Royal Medical Services
Bahrain Royal Medical Services (Arabic: الخدمات الطبية الملكية البحرينية, also known as Bahrain Defense Force Hospital, is one of the major hospitals in the Kingdom of Bahrain, and the only hospital in the country where free health care is provided exclusively for Bahraini military personnel.
Lester J. Ulrich
Lester Julius Ulrich (November 15, 1908 – November 25, 1991) was an American lawyer and politician.

Ulrich was born in Willow Creek, Blue Earth County, Minnesota. He graduated from Amboy High School in Amboy, Minnesota in 1926. Ulrich went to Macalester College and then received his law degree from University of Minnesota Law School. He lived in Amboy, Minnesota and practiced law in Amboy, Minnesota. Ulrich served in the Minnesota House of Representatives in 1933 and 1934. Ulrich died at his home in Crosslake, Crow Wing County, Minnesota.

Crow Wing County, Minnesota
Crow Wing County is a county in the East Central part of the U.S. state of Minnesota. As of the 2020 census, the population was 66,123. Its county seat is Brainerd. The county was formed in 1857, and was organized in 1870.

Crow Wing County is included in the Brainerd, MN Micropolitan Statistical Area.
The Great Louse Detective
"The Great Louse Detective" is the sixth episode of the fourteenth season of the American animated television series The Simpsons. It originally aired on the Fox network in the United States on December 15, 2002. In the episode, the Simpson family wins a free spa weekend and Homer is nearly killed when a mysterious figure locks him in a sauna. Chief Wiggum decides to hire someone who can think like a murderer in order to find the mystery assailant. Bart's arch-enemy Sideshow Bob is sent to live with the Simpsons so he can help find Homer's attempted killer, who turns out to be the son of the late Frank Grimes.

Since airing, the episode has received generally positive reviews from critics. The episode's title is a reference to the 1986 Disney animated feature The Great Mouse Detective.

Traditional animation
Traditional animation (or classical animation, cel animation, or hand-drawn animation) is an animation technique in which each frame is drawn by hand. The technique was the dominant form of animation of the 20th century in the United States until there was a shift to computer animation in the industry, such as 3D computer animation. Despite this, the process remains commonly used primarily in the form of digital ink and paint for television and film, especially when outsourced.
Bruce Billings (cartoonist)
Bruce Billings is an openly gay cartoonist, creator of the LGBT-themed comic strip Castro, which ran in the 1970s and 1980s in San Francisco gay newspapers such as The Voice. Castro nominally starred a dog (based on Billings') who lived in the Castro Street neighborhood of San Francisco with his owner (based on Billings himself), and the strip affectionately lampooned the gay male culture of the city. The strips were reprinted in Gay Comix, Meatmen, and Strip AIDS USA. In 1989, Billings and cartoonist Kurt Erichsen co-produced a flip book – a single bound volume with both covers formatted as the "front" – as Between the Sheets! (Billings' cover) and Under the Covers (Erichsen's). Billings retired to southern Oregon.

Strip AIDS
Strip AIDS and Strip AIDS U.S.A. are comics anthology volumes published in 1987 in the UK, and 1988 in the US (respectively). They combined short comics with educational and sometimes comedic themes, to educate readers about HIV disease and safer sex, and to raise funds for the care of people with AIDS.
Glass house effect
The Glass House Effect (or GHE) is the resulting phenomenon brought on by an awareness that one is subject to ubiquitous surveillance. In corporate environments, the transparency is considered a good idea, as it is believed this discourages corporate crime and other misfeasance.

The Glass House Effect can cause a sense of pessimism in persons who are subjected to such unrestrained monitoring. In such circumstances, solitude is conspicuously absent, and privacy is considered a thoughtcrime. The messages conveyed to the subject in such an environment usually involve some variation on the notion of Catch-22, such as:

There is no place to hide; nor should you want to.

Any exhibited avoidance behavior is considered a threat, and an invitation for additional scrutiny.

Solitude
Solitude, also known as social withdrawal, is a state of seclusion or isolation, meaning lack of socialisation. Effects can be either positive or negative, depending on the situation. Short-term solitude is often valued as a time when one may work, think, or rest without disturbance. It may be desired for the sake of privacy. Long-term solitude may stem from soured relationships, loss of loved ones, deliberate choice, infectious disease, mental disorders, neurological disorders such as circadian rhythm sleep disorder, or circumstances of employment or situation.

A distinction has been made between solitude and loneliness. In this sense, these two words refer, respectively, to the joy and the pain of being alone.
Lactarius fuliginellus
Lactarius fuliginellus is a species of fungus in the family Russulaceae. Described as a new species in 1962 by American mycologists Alexander H. Smith and Lexemuel Ray Hesler, the mushroom is found in North America.

Russulaceae
The Russulaceae are a diverse family of fungi in the order Russulales, with roughly 1,900 known species and a worldwide distribution. They comprise the brittlegills and the milk-caps, well-known mushroom-forming fungi that include some edible species. These gilled mushrooms are characterised by the brittle flesh of their fruitbodies.

In addition to these typical agaricoid forms, the family contains species with fruitbodies that are laterally striped (pleurotoid), closed (secotioid or gasteroid), or crust-like (corticioid). Molecular phylogenetics has demonstrated close affinities between species with very different fruitbody types and has discovered new, distinct lineages.

An important group of root-symbiotic ectomycorrhizal fungi in forests and shrublands around the world includes Lactifluus, Multifurca, Russula, and Lactarius. The crust-forming genera Boidinia, Gloeopeniophorella, and Pseudoxenasma, all wood-decay fungi, have basal positions in the family.
Melodi Grand Prix 2022
Melodi Grand Prix 2022 was the 60th edition of the Norwegian music competition Melodi Grand Prix (MGP). The contest is held annually and serves as the country's preselection for the Eurovision Song Contest. MGP was organized by Norway's public broadcaster NRK and was held in January and February 2022. The winner of the competition, Subwoolfer with "Give That Wolf a Banana", went on to represent Norway in the Eurovision Song Contest 2022 in Turin, Italy in May 2022.

Melodi Grand Prix
Melodi Grand Prix (Norwegian: [mɛlʊˈdiː ɡrɑŋ ˈpriː]), commonly known as Grand Prix and MGP, sometimes as Norsk Melodi Grand Prix, is an annual music competition organised by Norwegian public broadcaster Norsk rikskringkasting (NRK). It determines its entry for the Eurovision Song Contest, and has been staged almost every year since 1960.

The festival has produced three Eurovision winners, a non-winning televote winner and nine top-five placings for Norway at the contest. However, Norway holds the record for the number of entries who have come last since entering Eurovision; 12 in all. Despite this, the competition still makes considerable impact on music charts in Norway and other Nordic countries, with the 2008 winner topping the Norwegian charts.
Oxysterol
An oxysterol is a derivative of cholesterol obtained by oxidation involving enzymes and / or pro-oxidants. Such compounds play important roles in various biological processes such as cholesterol homeostasis, lipid metabolism (sphingolipids, fatty acids), apoptosis, autophagy, and prenylation of proteins; the mode of action of oxysterols in these effects is still poorly understood. Several oxysterols are associated with age-related diseases such as cardiovascular disease, eye disease (cataract, age-related macular degeneration), certain neurodegenerative diseases and cancers. 
Identifying therapies to regulate the body's production of oxysterols and their biological activities is of therapeutic interest.

A wider definition could encompass oxidized phytosterols, which are also sterols. The term "oxyphytosterols" may be used for distinction.

Sphingolipid
Sphingolipids are a class of lipids containing a backbone of sphingoid bases, which are a set of aliphatic amino alcohols that includes sphingosine.  They were discovered in brain extracts in the 1870s and were named after the mythological sphinx because of their enigmatic nature. These compounds play important roles in signal transduction and cell recognition. Sphingolipidoses, or disorders of sphingolipid metabolism, have particular impact on neural tissue. A sphingolipid with a terminal hydroxyl group is a ceramide. Other common groups bonded to the terminal oxygen atom include phosphocholine, yielding a sphingomyelin, and various sugar monomers or dimers, yielding cerebrosides and globosides, respectively. Cerebrosides and globosides are collectively known as glycosphingolipids.
Franciszek Kornicki
Franciszek Kornicki (18 December 1916 – 16 November 2017) was a Polish fighter pilot who served in the Polish Air Force in Poland, France and Britain during the Second World War and later served in the Royal Air Force (RAF). He died just a few weeks short of his 101st birthday and was the last surviving Polish fighter squadron commander from the Second World War.

Polish Air Force
The Polish Air Force (Polish: Siły Powietrzne, lit. 'Air Forces') is the aerial warfare branch of the Polish Armed Forces. Until July 2004 it was officially known as Wojska Lotnicze i Obrony Powietrznej (lit. 'Aerial and Air Defense Forces'). In 2014 it consisted of roughly 26,000 military personnel and about 475 aircraft, distributed among ten bases throughout Poland.

The Polish Air Force can trace its origins to the second half of 1917 and was officially established in the months following the end of World War I in 1918. During the invasion of Poland by Nazi Germany in 1939, 70% of its aircraft were destroyed. Most pilots, after the Soviet invasion of Poland on 17 September, escaped via Romania and Hungary to continue fighting throughout World War II in allied air forces, first in France, then in Britain, and later also the Soviet Union.
A Most Violent Year (soundtrack)
A Most Violent Year (Original Music from and Inspired By) is the film score to the 2014 film A Most Violent Year directed by J. C. Chandor starring Oscar Isaac and Jessica Chastain. The original score is composed by Edward Sharpe and the Magnetic Zeros frontman Alex Ebert and released through Community Music Group on December 16, 2014.

J. C. Chandor
Jeffrey McDonald "J. C." Chandor (/ˈʃændɔːr/; born November 24, 1973) is an American filmmaker, best known for writing and directing the critically acclaimed films Margin Call (2011), All Is Lost (2013), and A Most Violent Year (2014). His accolades include nominations for the Academy Awards, the Golden Bear and two National Board of Review victories for Best Picture.
Annie Blake
Annie Blake is a Canadian politician, who was elected to the Yukon Legislative Assembly in the 2021 Yukon general election. She represented the electoral district of Vuntut Gwitchin as a member of the Yukon New Democratic Party.

She finished in a 78–78 tie with incumbent MLA Pauline Frost on election night, which was further confirmed on a recount. Under Yukon election law, an exact tie between candidates is settled by drawing lots, and Blake was drawn as the winner. This was the second time in the history of the district, following the 1996 Yukon general election, that an election resulted in an exact tie settled in this manner.

Blake served as Deputy Speaker and Chair of Committee of the Whole of the Yukon Legislative Assembly. She also served as the Third Party critic for Health and Social Services, Justice, Tourism and Culture, and Youth Issues. She was defeated in the 2025 Yukon general election.

1996 Yukon general election
The 1996 Yukon general election was held on September 30, 1996 to elect the seventeen members of the 29th Yukon Legislative Assembly in Yukon Territory, Canada. The governing Yukon Party, a conservative party, was defeated by the social democratic New Democratic Party (NDP). The NDP formed a new majority government of the territory with 11 seats. Party leader Piers McDonald became Premier of Yukon. The Yukon Party and the centrist Yukon Liberal Party each won three seats, although Liberal leader Ken Taylor failed to be elected.
Brillhart
Brillhart is a surname. Notable people with the surname include:

Jeffrey Brillhart (born 1955), American organist, improviser, and conductor

Jessica Brillhart, American immersive director, writer and theorist

John Brillhart (1930–2022), American mathematician

Jeffrey Brillhart
Jeffrey Brillhart (born 1955) is an American organist, improviser, and conductor. He has served as director of music and fine arts at Bryn Mawr Presbyterian Church since January 1983. He is music director of Philadelphia's Singing City Choir, one of the first racially and religiously integrated symphonic choirs in America. He teaches organ improvisation at Yale University. He first gained national recognition for his abilities in organ improvisation after winning the 1994 National Competition in Organ Improvisation, sponsored by the American Guild of Organists.