hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Channel opener
A channel opener, also known as a channel activator, is a type of drug which facilitates ion flow through ion channels.

They include the following:

Potassium channel openers

Calcium channel openers

Sodium channel openers

Chloride channel openers

Calcium channel opener
A calcium channel opener is a type of drug which facilitates ion transmission through calcium channels.

An example is Bay K8644, which is an analogue of nifedipine that specifically and directly activates L-type voltage-dependent calcium channels.

In contrast to Bay K8644, which is not for clinical use, ambroxol is a frequently used mucolytic drug that triggers lysosomal secretion by mobilizing calcium from acidic calcium stores. This effect does most likely not occur by a direct interaction between the drug and a lysosomal calcium channel, but indirectly by neutralizing the acidic pH within lysosomes. Calcium permeable ion channels in lysosomal membranes that may be activated by a luminal pH increase include two pore channels (TPCs), mucolipin TRP channels (TRPMLs) and purinergic receptors of the P2X channel type.
Andropolia aedon
Andropolia aedon is a moth in the family Noctuidae first described by Augustus Radcliffe Grote in 1880. It is found in North America from British Columbia and Alberta south to California.

The wingspan is 42–46 mm (1.7–1.8 in). Adults are on wing from July to August.

The larvae feed on Alnus, Acer, Holodiscus discolor and Physocarpus capitatus.

Alder
Alders are trees of the genus Alnus in the birch family Betulaceae. The genus includes about 35 species of monoecious trees and shrubs, a few reaching a large size, distributed throughout the north temperate zone with a few species extending into Central America, as well as the northern and southern Andes.
Roscoe (novel)
Roscoe is a 2002 novel by American writer William Kennedy. It depicts an aging politician who is a key behind-the-scenes player in Albany, New York's Democratic Party machine. Although many names have been changed and events added, the book is based on the O'Connell Machine that controlled Albany for decades. Some occurrences in the novel are based on actual events. Many of Kennedy's older relatives were minor figures in the machine.

In 2013, the novel was adapted as an opera by composer Evan Mack. It made its debut in 2016.

Evan Mack
Evan Mack (born 1981) is an American composer, librettist and pianist on the faculty of Skidmore College.  He is "considered one of the most gifted composers of his generation by industry insiders." He is currently published with Hal Leonard, Alfred, and KDP Publishing.
Stephan König
Stephan König (born 4 October 1963) is a German composer, pianist and conductor. He is the musical director of the "LeipJAZZig-Orkester" and the chamber orchestra "artentfaltung" and is considered one of the most authoritative Jazz musicians in Leipzig.

Akademisches Orchester Leipzig
The Akademische Orchester Leipzig is an amateur symphony orchestra based in Leipzig. It was founded in 1954 by the conductor Horst Förster as the Collegium musicum of the University of Leipzig and was part of the University until 1991. Alongside other cultural institutions, it was subordinate to the university's "Main Department of Culture". At the time of reunification, the university separated from its orchestra, and since then it has no longer been an official part of the university. Instead, the Academic Orchestra reorganised itself in 1991 as a nonprofit organization. The artistic director is Horst Förster.
Hoffmaneumatidae
Hoffmaneumatidae is a family of millipedes belonging to the order Chordeumatida. This family includes two genera, one (Hoffmaneuma) found in the Russian Far East and the other (Japanoparvus) found in Japan. Millipedes in this family range from 4 mm to 6 mm in length. Adult millipedes in this family have only 28 segments (counting the collum as the first segment and the telson as the last), not the 30 segments usually found in this order. Adult males in this family feature a reduced leg pair 10 in addition to the two pairs (pairs 8 and 9) normally modified into gonopods in this order. In the adult male of the species Hoffmaneuma exiguum, for example, the gonopod complex derives from all three leg pairs rather than from just the usual two.

Genera:

Hoffmaneuma Golovatch, 1978

Japanoparvus Shear, Tanabe & Tsurusaki, 1997

Telson
The telson (from Ancient Greek  τέλσον 'headlands, limit') is the hindmost division of the body of an arthropod. Depending on the definition, the telson is either considered to be the final segment of the arthropod body, or an additional division that is not a true segment on account of not arising in the embryo from teloblast areas as other segments. It never carries any appendages, but a forked "tail" called the caudal furca may be present. The shape and composition of the telson differs between arthropod groups.
John McCormack (journalist)
John McCormack is a journalist and the Washington correspondent for National Review.

In a 2013 interview of journalist Robert Costa, Costa cites, among others, two examples of "great reporters" for conservative outlets.  One of them is John McCormack.

Early in his career as a journalist, McCormack was an intern for National Review in Washington, D.C. He later became a senior writer for The Weekly Standard from 2007 to 2018.

McCormack has appeared on a range of radio and TV news programs, including MSNBC's Morning Joe, CNN's Inside Politics, HBO’s Real Time, NPR's On Point, and Fox News' programs such as Special Report with Bret Baier.

McCormack, a native of Baldwin, Wisconsin, lives with his wife Lauren in Alexandria, Virginia.

Morning Joe
Morning Joe is an American morning news talk show, which airs weekdays from 6:00 a.m. to 10:00 a.m. Eastern Time on the cable news channel MS NOW. It features former US Representative (Independent) Joe Scarborough reporting and discussing the news of the day in a panel format with co-hosts Mika Brzezinski (whom Scarborough married in November 2018), Willie Geist, who regularly co-hosts from Tuesdays to Fridays, and Jonathan Lemire, along with recurring and special guests.
The Spike (essay)
"The Spike" is a 1931 essay by George Orwell in which he details his experience staying overnight in the casual ward of a workhouse (colloquially known as a "spike") near London. This episode in Orwell's life took place while he was intentionally living as a vagrant in and around London as part of the social experiment that would form the basis of his first book Down and Out in Paris and London. The events of this essay are also found in that book, though the essay is not reprinted verbatim in the book.

Orwell was in Paris, in August 1929, when he first sent a copy of "The Spike" to the New Adelphi magazine. The New Adelphi was a London periodical which was owned by John Middleton Murry. Murry had released editorial control to Sir Richard Rees and Max Plowman, and it was Plowman who accepted the work for publication. However, various revisions were required, and the work did not appear in print until April 1931.

John Middleton Murry
John Middleton Murry (6 August 1889 – 12 March 1957) was an English writer. He was a prolific author, producing more than 60 books and thousands of essays and reviews on literature, social issues, politics, and religion during his lifetime. A prominent critic, Murry is best remembered for his association with Katherine Mansfield, whom he married in 1918 as her second husband, for his friendship with D. H. Lawrence and T. S. Eliot, and for his friendship (and brief affair) with Frieda Lawrence. Following Mansfield's death, Murry edited her work.
George Pugh (rugby union)
Lt. George Harold Pugh (16 January 1890 – 5 September 1916) was a rugby union player who represented Australia.

Pugh, a lock, was born in Glebe, New South Wales and claimed 1 international rugby cap for Australia.

Pugh enlisted in the British army in 1912 and trained for six weeks in Liverpool, and joined the Liverpool Regiment as a second lieutenant. He joined the Australian Expeditionary Force in 1915. He was killed in action in the First World War while serving with the 4th Battalion of the Australian Infantry. He is buried at the Railway Dugouts Burial Ground in Ypres.

Ypres
Ypres (/ˈiːprə/ EE-prə, French: [ipʁ] ⓘ;  Dutch: Ieper [ˈipər] ⓘ; West Flemish: Yper; German: Ypern [ˈyːpɐn] ⓘ) is a Belgian city and municipality in the province of West Flanders. Though 
the Dutch name Ieper is the official one, the city's French name Ypres is most commonly used in English. The municipality comprises the city of Ypres/Ieper and the villages of Boezinge, Brielen, Dikkebus, Elverdinge, Hollebeke, Sint-Jan, Vlamertinge, Voormezele, Zillebeke, and Zuidschote. Together, they are home to about 34,900 inhabitants.

During the First World War, Ypres (or "Wipers" as it was commonly known by the British troops) was the centre of the Battles of Ypres between German and Allied forces.
La Roque-sur-Pernes
La Roque-sur-Pernes (French pronunciation: [la ʁɔk syʁ pɛʁn], literally La Roque on Pernes; Occitan: La Ròca de Pèrnas) is a commune in the southeastern French department of Vaucluse. As of 2023, the population of the commune was 437.

Vaucluse
Vaucluse (French: [voklyz]; Provençal: Vauclusa (Classical norm) or Vau-Cluso (Mistralian norm)) is a department in the southeastern French region of Provence-Alpes-Côte d'Azur. It had a population of 561,469 as of 2019. The department's prefecture is Avignon.

It is named after a spring, the Fontaine de Vaucluse, one of the largest karst springs in the world. The name Vaucluse itself derives from the Latin Vallis Clausa ("closed valley") as the valley ends in a cliff face from which the spring emanates.
Air Deccan
Air Deccan was an Indian regional airline operating from Ahmedabad, Gujarat. It flew to a total of four destinations using Beech 1900D aircraft, as of November 2019. On 5 April 2020, the airline ceased operations due to the effects of the COVID-19 pandemic and the ensuing lockdown.

Regional airline
A regional airline is a general classification of airline which typically operates scheduled passenger air service, using regional aircraft, between communities lacking sufficient demand or infrastructure to attract mainline flights. In North America, most regional airlines are classified as "fee-for-departure" carriers, operating their revenue flights as codeshare services contracted by one or more major airline partners. A number of regional airlines, particularly during the 1960s and 1970s, were classified as commuter airlines in the Official Airline Guide (OAG).
Joseph Le Vasseur Borgia
Joseph Le Vasseur Borgia (January 6, 1773 – June 28, 1839) was a lawyer, newspaper owner and political figure in Lower Canada.

He was born at Quebec in 1773, the son of a blacksmith, and studied at the Petit Séminaire de Québec. He articled as a lawyer, qualified to practice in 1800 and set up practice at Quebec. Le Vasseur Borgia helped found Le Canadien in 1806. In 1808, he was elected to the Legislative Assembly of Lower Canada for Cornwallis, representing it until 1820 when he was defeated, and then again from 1824 to 1830. For his association with Le Canadien, he was removed from his post in the militia in 1808 but he was named a militia captain in 1812 by Governor George Prevost.

He died at Quebec City in 1839 and was buried in the Cimetière des Picotés there. Le Vasseur Borgia had one son, Narcisse-Charles, who predeceased his father in 1834.

Collège François-de-Laval
Collège François-de-Laval (French pronunciation: [kɔlɛʒ fʁɑ̃swa də laval]), previously known as the Petit Séminaire de Québec ([pəti seminɛʁ də kebɛk]), is a private French-language Catholic secondary school in Vieux-Québec, Quebec City, Quebec.
Alyssum pulvinare
Alyssum pulvinare is a species of madwort, a flowering plant in the family Brassicaceae. A perennial herbaceous plant native to the Balkans, it grows on rocky places, rock ledges and dry grassy slopes, forming tufts about 6–15 cm high. It flowers in May and June.

The plant is found on Mount Oeta of central Greece (from the lower montane level up to 2100 m), conjectured to be present in northern Greece, reported from the south of the Republic of North Macedonia (including the mountain of Tzena or Kožuf between the two countries), the Iron Gates of southwestern Romania, and Bulgaria: at lower elevations (less than 900 m) in scattered localities in Kraishte, the middle Rhodopes, eastern Sredna Gora and the north-east of the country.

Alyssum thracicum Velen. is treated as a synonym by most, though not all, sources. Alyssum mildeanum Podp. is also commonly included as a synonym, although in some sources it is instead assigned to  A. stribrnyi.

Mount Oeta
Mount Oeta (/ˈɛtə/; Greek: Οίτη, polytonic Οἴτη, Oiti, also transcribed as Oite) is a mountain in Central Greece. A southeastern offshoot of the Pindus range, it is 2,152 m (7,060 ft) high. Since 1966, the core area of the mountain is a national park, and much of the rest has been declared a special area under Natura 2000.
Åland women's official football team
The Åland women's official football team represents Åland in women's association football and is controlled by the Åland Football Association (ÅFF). the team isn't affiliated with FIFA  nor UEFA. The team mainly competes in the Island Games. the team was crowned champions winning gold medals three times (2007, 2009 and 2011).

Åland also has a successful women's club football side, Åland United which competes in the Kansallinen Liiga.

Island Games
The Island Games are biennial international multi-sports events organised by the International Island Games Association (IIGA). Competitor teams each represent different island communities (with one team from the peninsula of Gibraltar) which are IIGA members. Currently, all competitor teams represent non-sovereign territories of European nations—some within European waters and some further overseas.

The games are being hosted by the Faroe Islands in 2027. The previous edition was the 2025, which took place in Orkney with around 2,200 competitors from 24 islands or island groups participating in 14 sports.
Kidnappings of John Fru Ndi
John Fru Ndi, the leader of the Cameroonian  Social Democratic Front was kidnapped twice during the Anglophone Crisis. The first incident was a brief and bloodless, with Fru Ndi being held by Ambazonian separatist fighters for a few hours and then released the same day. The second kidnapping was more dramatic, with gunmen breaking into his home, shooting his bodyguard in the leg and subjecting Fru Ndi to a rough treatment.

Northwest Region (Cameroon)
The Northwest Region, or North-West Region (French: Région du Nord-Ouest) is a region with special status in Cameroon. Its capital is Bamenda. The Northwest Region was part of the Southern Cameroons, found in the western highlands of Cameroon. It is bordered to the southwest by the Southwest Region, to the south by the West Region, to the east by the Adamawa Region, and to the north by Nigeria. Various Ambazonian nationalist and separatist factions regard the region as being distinct as a polity from Cameroon.

In 1919, the Northwest Region became solely administered by the United Kingdom. In 1961, the region joined the Cameroon. Ambazonian separatists regard both the North-West and South-West regions as being constituent components of their envisaged breakaway state.
Crucibulum (fungus)
Crucibulum is a genus in the Nidulariaceae, a family of fungi whose fruiting bodies resemble tiny egg-filled bird's nests. Often called "splash cups", the fruiting bodies are adapted for spore dispersal by using the kinetic energy of falling drops of rain. The "eggs" inside the bird's nests (technically known as peridioles) are hard waxy shells containing spores, and tend to stick to whatever nearby herbage they land on, thus increasing the odds of being consumed and dispersed by herbivorous animals.

Members of this genus are saprobic, obtaining nutrients from dead organic matter, and are typically found growing on decayed wood and wood debris. The three known Crucibulum species (C. laeve, C. parvulum, and C. cyathiforme) are distinguished from other genera of the Nidulariaceae by their relatively simple funiculus – a cord of hyphae that connects the peridiole (the "eggs") to the exterior of the bird's nest.

Lignin
Lignin is a class of complex organic polymers that form key structural materials in the support tissues of most plants.  Lignins are particularly important in the formation of cell walls, especially in wood and bark, because they lend rigidity and do not rot easily. Chemically, lignins are polymers made by the cross-linking of phenolic precursors.
An Insider's View of Mormon Origins
An Insider's View of Mormon Origins is a 2002 book about the origins of Mormonism by Grant H. Palmer, a member of the Church of Jesus Christ of Latter-day Saints (LDS Church) who was a Church Educational System instructor and Institute director with a master's degree in history.

Palmer's stated purpose in writing the book was to incorporate recent critical historical and scholarly studies of LDS history in an orthodox defense of the faith.  He states that his aim is to "increase faith, not diminish it".

Maxwell Institute
The Neal A. Maxwell Institute for Religious Scholarship, or Maxwell Institute, is a research institute at Brigham Young University (BYU). The institute consists of faculty and visiting scholars who study religion, primarily the Church of Jesus Christ of Latter-day Saints (LDS Church). The institute is named after a former LDS Church apostle, known for his writings and sermons.

The LDS Church identifies the Maxwell Institute as one of several third-party church affiliates offering gospel study resources.
The Men Who Stare at Goats (film)
The Men Who Stare at Goats is a 2009 satirical black comedy war film directed by Grant Heslov and written by Peter Straughan. It is loosely based on the 2004 book by Jon Ronson, about an investigation into attempts by the U.S. military to employ psychic powers as a weapon. The film stars George Clooney, Ewan McGregor, Jeff Bridges, and Kevin Spacey.

The Men Who Stare at Goats premiered at the 66th Venice International Film Festival on September 8, 2009, and was released in the United States and the United Kingdom on November 6. The film received mixed reviews from critics.

66th Venice International Film Festival
The 66th annual Venice International Film Festival, was held from 2 to 12 September 2009, at Venice Lido in Italy.

Taiwanese filmmaker Ang Lee was the jury president for the main competition. Italian actress Maria Grazia Cucinotta was the Host of the opening and closing ceremonies. The Golden Lion was awarded to Lebanon by Samuel Maoz.

The festival opened with Baarìa by Giuseppe Tornatore, and the closed with Chengdu, I Love You by Fruit Chan and Cui Jian.
This Is Tom Jones
This Is Tom Jones was a British Associated Television variety series presented by Tom Jones. It was exported to the United States by ITC Entertainment and networked there by the American Broadcasting Company. The series ran between 1969 and 1971 to total 65 colour episodes. Jones was nominated for a Golden Globe Award for "Best Actor in a Television Series - Musical or Comedy" in 1969. The series also featured comedy sketches by the Ace Trucking Company improvisational group, featuring Fred Willard and Patti Deutsch, among others.

Golden Globe Award for Best Actor – Television Series Musical or Comedy
The Golden Globe Award for Best Actor – Television Series Musical or Comedy is a Golden Globe Award presented annually by the Hollywood Foreign Press Association (HFPA). It is given in honor of an actor who has delivered an outstanding performance in a leading role on a musical or comedy television series for the calendar year.

It was first awarded at the 19th Golden Globe Awards on March 5, 1962, under the title Best TV Star – Male to John Charles Daly and Bob Newhart. The nominees for the award announced annually starting in 1963. The award initially honored actors in both comedy and drama genres until 1969, when the award was split into categories that honored comedic and dramatic performances separately. It was presented under the new title Best TV Actor – Musical or Comedy and in 1980 under its current title.

Since its inception, the award has been given to 45 actors. Alan Alda has won the most awards in this category with six wins and received the most nominations at 11.
Lester Frank Ward
Lester Frank Ward (June 18, 1841 – April 18, 1913) was an American botanist, paleontologist, and sociologist. The first president of the American Sociological Association, James Q. Dealey characterized Ward as a "great pioneer" in the development of American sociology, with contemporaries referring to him as "the Nestor of American sociologists". His 1883 work Dynamic Sociology was influential in establishing sociology as a distinct field in the United States. However, despite its initial impact his work was quickly sidelined during the later institutionalization and development of American sociology.

G. P. Putnam's Sons
G. P. Putnam's Sons is an American book publisher based in New York City, New York. The publisher was founded in 1838 and features books by authors such as Renée Ahdieh, C. J. Box, Edgar Allan Poe, and many others. Since 1996, it has been an imprint of the Penguin Group.
Colla mac Fergusso
Colla mac Fergusso (or Colla mac Forgusso, died 796) was a possible King of Connacht from the Uí Briúin branch of the Connachta. He was the son of Forggus mac Cellaig (died 756), a previous king. The sept of Uí Briúin he belonged to was the Síl Cellaig of Loch Cime (Lough Hackett, near Headford in modern County Galway) named for his grandfather Cellach mac Rogallaig (died 705).

Though omitted from king lists such as the Book of Leinster, he is called king at his death obit in the Annals of Innisfallen. However, the Annals of Ulster say that Muirgius mac Tommaltaig (died 815) became king after defeating Cináed mac Artgail (died 792) at the Battle of Sruth Cluana Argai (Cloonargid, Roscommon, Co.) in 792. His death is recorded in this annal as King of Uí Briúin.

Colla was the last king from the Síl Cellaig sept. This sept was later displaced from this area by the Uí Briúin Seóla.

Connachta
The Connachta are a group of medieval Irish dynasties who claimed descent from the legendary High King Conn Cétchathach (Conn of the Hundred Battles). The modern western province of Connacht (Irish Cúige Chonnacht, province, literally "fifth", of the Connachta) takes its name from them, although the territories of the Connachta also included at various times parts of southern and western Ulster and northern Leinster. Their traditional capital was Cruachan (modern Rathcroghan, County Roscommon).
Leslie Scalapino
Leslie Scalapino (July 25, 1944 – May 28, 2010) was an American poet, experimental prose writer, playwright, essayist, and editor, sometimes grouped in with the Language poets, though she felt closely tied to the Beat poets.  A longtime resident of California's Bay Area, she earned an M.A. in English from the University of California at Berkeley. One of Scalapino's most critically well-received works is Way (North Point Press, 1988), a long poem which won the Poetry Center Award, the Lawrence Lipton Prize, and the American Book Award.

Fiction Collective Two
Fiction Collective Two (FC2) is an author-run, not-for-profit publisher of avant-garde, experimental fiction supported in part by the University of Utah, the University of Alabama Press, Central Michigan University, Illinois State University, private contributors, arts organizations and foundations, and contest fees.

FC2 is "devoted to publishing fiction considered by America's largest publishers too challenging, innovative, or heterodox for the commercial milieu ... FC2's mission has been and remains to publish books of high quality and exceptional ambition whose styles, subject matter, or forms push the limits of American publishing and reshape our literary culture."