hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Orteronel
Orteronel (TAK-700) is a nonsteroidal CYP17A1 inhibitor that was being developed for the treatment of cancer by Takeda Pharmaceutical Company in conjunction with Millennium Pharmaceuticals. It completed two phase III clinical trials for metastatic, hormone-refractory prostate cancer but failed to extend overall survival rates, and development was voluntarily terminated as a result.

Orteronel is an androgen biosynthesis inhibitor. It selectively inhibits the enzyme CYP17A1 which is expressed in testicular, adrenal, and prostatic tumor tissues. CYP17 catalyzes two sequential reactions: (a) the conversion of pregnenolone and progesterone to their 17α-hydroxy derivatives by its 17α-hydroxylase activity, and (b) the subsequent formation of dehydroepiandrosterone (DHEA) and androstenedione, respectively, by its 17,20-lyase activity. DHEA and androstenedione are androgens and precursors of testosterone. Inhibition of CYP17 activity thus decreases circulating levels of testosterone.

CYP17A1
Cytochrome P450 17A1 (steroid 17α-monooxygenase, 17α-hydroxylase, 17-alpha-hydroxylase, 17,20-lyase, 17,20-desmolase) is an enzyme of the hydroxylase type that in humans is encoded by the CYP17A1 gene on chromosome 10. It is ubiquitously expressed in many tissues and cell types, including the zona reticularis and zona fasciculata (but not zona glomerulosa) of the adrenal cortex as well as gonadal tissues. It has both 17α-hydroxylase and 17,20-lyase activities, and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. More specifically, the enzyme acts upon pregnenolone and progesterone to add a hydroxyl (-OH) group at carbon 17 position (C17) of the steroid D ring (the 17α-hydroxylase activity, EC 1.14.14.19), or acts upon 17α-hydroxyprogesterone and 17α-hydroxypregnenolone to split the side-chain off the steroid nucleus (the 17,20-lyase activity, EC 1.14.14.32).
Northern Alberta kimberlite province
The northern Alberta kimberlite province (NAKP) consists of three groups of diatremes or volcanic pipes in north-central Alberta, Canada, most of which are kimberlites and some of which are diamondiferous. They are called the Birch Mountains (BM), Buffalo Head Hills (BHH), and the Mountain Lake cluster (ML), and they were discovered between about 1990 and 1997. Most of the diatremes were emplaced during the Late Cretaceous Epoch (Turonian to Maastrichtian stages) although a few are as young as early Paleocene.

Volcanic pipe
Volcanic pipes or volcanic conduits are subterranean geological structures formed by the violent, supersonic eruption of deep-origin volcanoes. They are a type of diatreme composed of a deep, narrow carrot-shaped cone of solidified magma usually composed of kimberlite or lamproite. These rocks reflect the composition of the volcanoes' deep magma sources rich in magnesium. They are the primary source of diamonds and are mined for this purpose. While diatremes are common, being the second commonest form of magma extrusion reaching the surface, volcanic pipes are relatively rare.
Japanese destroyer Murakumo
Three Japanese destroyers have been named Murakumo (叢雲 / むらくも, ”massed clouds”):

Japanese destroyer Murakumo (1898), a Murakumo-class destroyer of the Imperial Japanese Navy in the Russo-Japanese War and World War I

Japanese destroyer Murakumo (1928), a Fubuki-class destroyer of the Imperial Japanese Navy in World War II

JDS Murakumo, a Minegumo-class destroyer of the Japan Maritime Self-Defense Force

Fubuki-class destroyer
The Fubuki-class destroyers (吹雪型駆逐艦, Fubukigata kuchikukan) were a class of twenty-four destroyers of the Imperial Japanese Navy. The Fubuki class has been described as the world's first modern destroyer. They remained effective in their role to the end of World War II, despite being much older than contemporary ships of foreign nations.
El Frasno
El Frasno is a municipality in the province of Zaragoza, Aragon, Spain. According to the 2004 census (INE), the municipality had a population of 476 inhabitants.

This town is located in the Sierra de Vicort range close to the Carretera Nacional N-II highway. The Puerto del Frasno mountain pass is named after it. According to the 2010 census the town had a population of 141 inhabitants.

Province of Zaragoza
Zaragoza (Spanish pronunciation: [θaɾaˈɣoθa]), also called Saragossa in English, is a province of northern Spain, in the central part of the autonomous community of Aragon. Its capital is the city of Zaragoza, which is also the capital of the autonomous community. Other towns in the province include La Almunia de Doña Godina, Borja, Calatayud, Caspe, Ejea de los Caballeros, Tarazona, and Utebo.

Its area is 17,274 km², which makes it the fourth-largest Spanish province by land area. Its population was 954,811 in 2018, accounting for slightly over 72% of the entire population of Aragon; nearly 75% of those lived in the capital. Its population density was 51/km². It contains 292 municipalities, of which more than half are villages with fewer than 300 people.

The main language throughout the province is Spanish (with official status), although Catalan is spoken in the easternmost part (Bajo Aragón-Caspe comarca and Mequinenza municipality).
Kusum Kusum Prem
Kusum Kusum Prem (Bengali: কুসুম কুসুম প্রেম) is a Bangladeshi Bengali language film. It was released in 2011. The film was directed by Mushfiqur Rahman Gulzar who also wrote the story. The film was produced by Impress Telefilm Limited. Film stars Moushumi, Ferdous and Riaz in lead roles along with ATM Shamsuzzaman, Prabir Mitra, Khaleda Akter Kalpana, Amol Bose and Nasima Khan.

Impress Telefilm
Impress Telefilm Limited is a media production house in Bangladesh, formed in 2003. The company produces film, drama, and drama serials, music videos, variety shows, magazine programmes, musical programmes, and documentaries as well as TV commercials. It was founded by Faridur Reza Sagar.

From Bangladesh, 9 different films of Impress Telefilm has got Bangladeshi submissions for the Oscar for Foreign Language Film Competition 9 times.
Maddux (surname)
Maddux is an English surname.  It is a variant of Maddox.  Notable people with the surname include:

Don Maddux (born 1940), American politician from Ohio

Earle H. Maddux (1906–1974), American Anglo-Catholic liturgist

Elmer Maddux (1934–2019), American politician

Greg Maddux (born 1966), American baseball player, brother of Mike

Jared Maddux (1911–1971), American politician from Tennessee

Jeff Maddux (born 1988), American football player

Masha Dashkina Maddux, Ukrainian dancer

Mike Maddux (born 1961), American baseball player and coach, brother of Greg

Roger Maddux (born 1948), American mathematician

Sam Maddux Jr. (1915–1990), United States Air Force officer

Stu Maddux (born 1965), American writer and cinematographer

Tracy Maddux, American music business executive

Earle H. Maddux
Earle Hewitt Maddux SSJE (June 18, 1906 – December 1974) was a notable American Anglo-Catholic liturgist in the Episcopal Church during the twentieth century. He was professed in the Society of St. John the Evangelist in 1936. He is known best for his edition of The American Missal, first published in 1951. (This is not to be confused with the Anglican Missal or the English Missal.) Maddux was born in Fairfield, Iowa and ordained to the priesthood on June 15, 1930 in Denver, Colorado.

Maddux was chaplain to the Order of St. Anne in Arlington, Massachusetts from 1941 to 1948, and chaplain to the All Saints Sisters of the Poor in Catonsville, Maryland from 1951 to until his retirement from active ministry in 1972.
Lake Ngapakaldi to Lake Palankarinna Fossil Area
The Lake Ngapakaldi to Lake Palankarinna Fossil Area is a group of fossil sites located in the Australian state of South Australia within the Tirari Desert in the north-eastern part of the state's Far North region.  The group has an overall area of 35 square kilometres (14 sq mi) and is located about 70 kilometres (43 mi) east of Lake Eyre and about 100 kilometres (62 mi) north-north-east of Marree, off the Birdsville Track near Etadunna Station.

Far North (South Australia)
The Far North is a region that covers about 70 per cent of the Australian state of South Australia. It extends across the entire width of the state – about 1200 kilometres (750 miles) – for approximately the northernmost 750 kilometres (470 miles). The state government defines the Far North region similarly, although it separately delineates the Maralinga Tjarutja Lands, the Yalata Aboriginal community and other unincorporated crown lands in the state's far west, which are officially considered part of the Eyre and Western region. Colloquially, South Australians regard anywhere north of Port Augusta as the Far North.

The Far North is by far the least populated region of South Australia.
El Castillo del Terror (2006)
El Castillo del Terror (2006) was the second annual El Castillo del Terror professional wrestling event produced by the International Wrestling Revolution Group. It took place on November 2, 2006, at Arena Naucalpan in Naucalpan, State of Mexico. The show featured the eponymous main event match; a nine-man Steel Cage Match where the last two men in the cage were forced to wrestle each other and the loser would be forced to unmask under Luchas de Apuestas, or "Bet rules". For the 2006 event Ave Fénix, Bacteria, Fabián el Gitano, Fantasma de la Ópera, El Felino, El Hijo del Diablo, Macho II, Nitro and Xibalva all wagered their masks on the outcome of the match. The match came down to Ave Fénix and Macho II, with Fénix pinning Macho II to force him to unmask afterwards.

Card (sports)
In sports, a card lists the matches taking place in a title match combat-sport event. Cards include a main event match and the undercard listing the rest of the matches. The undercard may be divided into a midcard and a lower card, according to the perceived importance of the matches.  Promoters schedule matches to occur in ascending order of importance.
Parish of Nattung
Nattung, New South Wales is a civil parish of Cowley County, New South Wales.
Nattung is in the Snowy Monaro Regional Council at 35°44′54″S 148°36′04″E﻿ / ﻿35.74833°S 148.60111°E﻿ / -35.74833; 148.60111. It lies in the headwaters of the Murrumbidgee River and in the Kosciuszko National Park. It is uninhabited.

Cowley County, New South Wales
Cowley County is one of the 141 cadastral divisions of New South Wales. It contains the locality of Cavan. It was originally bordered on the north, east and part of the south by the Murrumbidgee River, and on the west by the Goodradigbee River. A large part of the county was transferred to the Commonwealth to make the Australian Capital Territory in 1909, with the remaining part the area to the north-west of the ACT as far north as the Burrinjuck Dam, and thin strips of land along the western, southern and south-eastern borders of the ACT.

Cowley County is named in honour of Henry Richard Charles Wellesley, First Earl Cowley (1804–1884).
Love Someone (Lukas Graham song)
"Love Someone" is a song by Danish pop and soul band Lukas Graham. It was released on 7 September 2018 as the lead single from their third studio album, 3 (The Purple Album). The song was written by James Alan, Stefan Forrest, Morten Ristorp, Lukas Forchhammer, Jaramye Daniels, Morten Pilegaard and David Labrel. The song debuted at number one on the Danish Singles Chart.

The song was featured on the third episode of season 15 of The Bachelorette and the Hallmark Channel film, Love on the Menu.

The Bachelorette (American TV series) season 15
The fifteenth season of The Bachelorette premiered on May 13, 2019. The season featured Hannah Brown, a 24-year-old interior designer from Northport, Alabama. Brown was crowned Miss Alabama USA 2018 and represented Alabama at Miss USA 2018.

Brown finished in seventh place on season 23 of The Bachelor featuring Colton Underwood. She was the first Bachelorette lead not to have placed in the top four of a season of The Bachelor, and is the youngest bachelorette in the show's history.

The season concluded on July 30, 2019, with Brown accepting a proposal from 25-year-old singer/songwriter Jed Wyatt. However, during the After The Final Rose special, it was revealed that they called off their engagement in June 2019 after Brown discovered that Wyatt had a girlfriend at home. Wyatt also admitted that he only went on the show to promote his music career.
Katri Kaarlonen
Katri Kaarlonen (née Kallio; 28 March 1915 – 1 October 2008) was a Finnish politician, who served as a Member of Parliament for the Turku Province (south) constituency (now Varsinais-Suomi), representing the Centre Party.

She was a member of the electoral college in the 1962 and 1968 presidential elections, helping to re-elect her party's candidate, Urho Kekkonen.

Outside politics, Kaarlonen worked as a teacher of gardening, as well as running the family farm in Perniö. In 1985, she was granted the honorary title of Opetusneuvos (lit. 'Teaching counselor').

Her father was the 4th President of Finland, Kyösti Kallio. Her older sister Kerttu Saalasti was also a long-serving Member of Parliament, and one-time Minister of Education.

Perniö
Perniö (Finnish pronunciation: [ˈperniø]; Swedish: Bjärnå) is a former municipality of Finland. It was consolidated with Salo on January 1, 2009.

It is located in the province of Western Finland and is part of the Southwest Finland region. The municipality had a population of 6,026 (2004-12-31) and covered an area of 407.79 km² (excluding sea) of which 9.91 km² is inland water. The population density was 15.15 inhabitants per km².

The municipality was unilingually Finnish.
Jovan Pačić
Jovan Pačić (November 6, 1771, Baja - December 4, 1849  Budapest) was a Serbian soldier, painter and poet.

Jovan Pačić went to school in Kalocsa. In 1792 or 1793, he joined the army and fought against the French. In 1812 he suffered an injury when a sword cut through his mouth. He retired after a year of recuperation. As a retired cavalry captain, he moved to Novi Sad, and soon after settled in Győr in 1838. Jovan Pačić turned to painting and poetry in his leisure. He primarily painted landscapes and genre art. He was praised by his contemporaries.

Kalocsa
Kalocsa (Hungarian pronunciation: [ˈkɒlot͡ʃɒ]; Croatian: Kaloča or Kalača; Serbian: Kaloča or Калоча; German: Kollotschau) is a town in Bács-Kiskun county, Hungary. It lies 142 km (88 mi) south of Budapest. It is situated in a marshy but highly productive district, near the left bank of the Danube River.  Historically it had greater political and economic importance than at present.
Microbulbifer salipaludis
Microbulbifer salipaludis is a moderate halophilic bacteria. It is Gram-negative, non-motile, non-spore-forming and rod-shaped. The type strain of the species is strain SM-1T (=KCCM 41586T =JCM 11542T).

Halophile
A halophile (from the Greek word for 'salt-loving') is an extremophile that thrives in high salt concentrations. In chemical terms, halophile refers to a Lewis acidic species that has some ability to extract halides from other chemical species.

While most halophiles are classified into the domain Archaea, there are also bacterial halophiles and some eukaryotic species, such as the alga Dunaliella salina and fungus Wallemia ichthyophaga. Some well-known species give off a red color from carotenoid compounds, notably bacteriorhodopsin.

Halophiles can be found in water bodies with salt concentration more than five times greater than that of the ocean, such as the Great Salt Lake in Utah, Owens Lake in California, the Lake Urmia in Iran, the Dead Sea, and in evaporation ponds. They are theorized to be a possible analogues for modeling extremophiles that might live in the salty subsurface water ocean of Jupiter's Europa and similar moons.
Imam Sahib District
Imam Sahib District (ولسوالی امام‌صاحب‬) is situated in the northern part of Kunduz Province, Afghanistan. It borders with Qalay-I-Zal District to the west, Tajikistan to the north (along the Panj river), with Archi District to the east and Kunduz District to the south. It has an estimated population of 232,846 as of 2021, which include ethnic Uzbeks at 45%, Pashtuns at 25%, Tajiks at 25% and Hazaras at 1%. The district center is the town of Imam Sahib, located in the northern part of the district. The other main town in the district is Sher Khan Bandar, which serves as Afghanistan's main port of entry to Tajikistan.

The district is one of the richest in Afghanistan. The land is very fertile and well irrigated and has not suffered drought. The medical and educational facilities are better than in other districts of Kunduz.

Uzbeks
The Uzbeks (Uzbek: Oʻzbeklar; Ўзбеклар; اۉزبېکلر‎) are a Turkic ethnic group native to Central Asia, being the largest Turkic ethnic group in the area. They comprise the majority population of Uzbekistan, next to Tajiks and Karakalpak minorities, and also form minority groups in Afghanistan, Tajikistan, Kyrgyzstan, Kazakhstan, Turkmenistan, Russia, and China. Uzbek diaspora communities also exist in Turkey, Saudi Arabia, United States, Ukraine, Pakistan, and other countries.
Ennis (parish)
Ennis is a parish in County Clare, Ireland, and part of the Abbey grouping of parishes within the Roman Catholic Diocese of Killaloe.

Current (2022) co-parish priest and team leader is Tom Ryan. He leads a team of 8 priests.

The present parish contains much of the mediaeval parish of Dromcliffe. The part around Inch was transferred to the parish of Kilmaley in the eighteenth century
Contrary to the name, it does not contain all of the town of Ennis, as the eastern part around Roslevan belongs to the parish of Doora-Barefield.

County Clare
County Clare (Irish: Contae an Chláir) is a county in the province of Munster in the  Southern part of Ireland, bordered on the west by the Atlantic Ocean. Clare County Council is the local authority. The county had a population of 127,938 at the 2022 census. The county seat and largest settlement is Ennis.
Nortel Certifications
Nortel Certifications are IT professional certifications for Nortel products and IEEE standard technologies. There were two major levels of certification, Specialist and Expert. Within each level were three sublevels; technology, support, and design. The certification exams were administered at Prometric testing centers.  Various training courses were held by Nortel regional training partners, such as Global Knowledge.  As Nortel began to exit certain businesses and divest itself, they retired various certification training programs and exams.  They retired the GSM-related programs in March 2008, Optical and Carrier VoIP programs in September 2009, and lastly the Enterprise programs in November 2010.

Prometric
Prometric, also known as Prometric Testing, is an American test administration company. The corporate headquarters are located in Baltimore, Maryland, United States. The company manages a network of test centers with thousands of sites in 160 countries, where various examinations are conducted.
Eriosoma ulmi
Eriosoma ulmi, the elm-currant aphid, is a species of aphid in the family Aphididae found in Asia and Europe. It is a true bug and sucks sap from plants. It was described by Carl Linnaeus in his Systema Naturae, published in 1758. The mite causes abnormal plant growths, known as galls on their primary host, elm trees (Ulmus species). To complete there life-cycle they feed on a secondary host, the roots of currant bushes (Ribes species).

Aphididae
The Aphididae are a very large insect family in the aphid superfamily (Aphidoidea), of the order Hemiptera. These insects suck the sap from plant leaves. Several thousand species are placed in this family, many of which are considered plant/crop pests. They are the family of insects containing most plant virus vectors (around 200 known) with the green peach aphid (Myzus persicae) being one of the most prevalent and indiscriminate carriers.
Teslui, Dolj
Teslui is a commune in Dolj County, Oltenia, Romania with a population of 2,781 people. It is composed of eight villages: Coșereni, Fântânele, Preajba de Jos, Preajba de Pădure, Teslui, Țărțăl, Urieni and Viișoara-Moșneni.

Dolj County
Dolj County (Romanian pronunciation: [dolʒ] ⓘ; originally meant Dol(no)-Jiu, "lower Jiu", as opposed to Gorj (upper Jiu)) is a county (județ) of Romania on the border with Bulgaria, in Oltenia, with the capital city at Craiova.
Orange-billed sparrow
The orange-billed sparrow (Arremon aurantiirostris) is a species of bird in the family Passerellidae.
In Central America it is found in Belize, Costa Rica, Guatemala, Honduras, Mexico, Nicaragua and Panama. In northwestern South America the orange-billed sparrow is found in Colombia, Ecuador and northern Peru. The species are black and as the name suggests, have an orange bill. Its natural habitat is subtropical or tropical moist lowland forest.

New World sparrow
New World sparrows are a group of mainly New World passerine birds, forming the family Passerellidae. They are seed-eating birds with conical bills, brown or gray in color, and many species have distinctive head patterns.

Although they share the name sparrow, New World sparrows are more closely related to Old World buntings than they are to the Old World sparrows (family Passeridae). New World sparrows are also similar in both appearance and habit to finches, with which they sometimes used to be classified.
Żerniki, Jędrzejów County
Żerniki (Polish pronunciation: [ʐɛrˈɲikʲi]) is a village in the administrative district of Gmina Sobków, within Jędrzejów County, Świętokrzyskie Voivodeship, in south-central Poland. It lies approximately 8 km (5 mi) north-west of Sobków, 16 km (10 mi) north-east of Jędrzejów, and 21 km (13 mi) south-west of the regional capital Kielce.

Jędrzejów
Jędrzejów (Polish: [jɛnˈdʐɛjuf] ⓘ; Yiddish: יענדזשעוו, romanized: Yendzshev, Latin: Andreiow) is a town in southern Poland, located in the Świętokrzyskie Voivodeship. It lies approximately 35 kilometres (22 miles) southwest of Kielce. It is the capital of Jędrzejów County. It has 16,139 inhabitants (2011).
2008 Carrera Panamericana
The 2008 edition of the Carrera Panamericana Mexican sports car racing event started in Tuxtla Gutiérrez, Chiapas and finished in Nuevo Laredo, Tamaulipas. This edition was composed of 7 stages. Bill Beilharz and Jorge Ceballos won this edition.

Tuxtla Gutiérrez
Tuxtla Gutiérrez, or Tuxtla, (Spanish: [ˈtuɣstla ɣuˈtjeres] ⓘ, Nahuatl: [ˈtuʃt͡ɬa]) is the capital and the largest city of the Mexican southeastern state of Chiapas. It is the seat of the municipality of the same name, which is the most developed and populous in the state. A busy government, commercial and services-oriented city, Tuxtla had one of the fastest-growing rates in Mexico over the last 40 years. Unlike many other areas in Chiapas, it is not a major tourist attraction, but a transportation hub for tourists coming into the state, with a large airport and a bus terminal.
1998 Mid-American Conference baseball tournament
The 1998 Mid-American Conference baseball tournament took place in May 1998. The top three regular season finishers from each division met in the double-elimination tournament held at Warren E. Steller Field on the campus of Bowling Green State University in Bowling Green, Ohio. This was the tenth Mid-American Conference postseason tournament to determine a champion. The top seed from the east, Bowling Green, won their first tournament championship to earn the conference's automatic bid to the 1998 NCAA Division I baseball tournament.

Steller Field
Warren E. Steller Field is a baseball field at Bowling Green State University in Bowling Green, Ohio, where the Bowling Green Falcons baseball team plays. The field is named after Warren E. Steller, a former BGSU instructor and former coach of the Bowling Green's football (1924–34) and baseball (1925, 1928–59) teams.  It was officially named for Warren E. Steller in 1967.  Steller Field is located just north of the Slater Family Ice Arena on the eastern side of the campus.  The dimensions of the field from home plate to the outfield fences are 340 feet to left field, 400 feet to center field, and 340 feet to right field.