hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
D-proline reductase (dithiol)
In enzymology, a D-proline reductase (dithiol) (EC 1.21.4.1) is an enzyme that catalyzes the chemical reaction

5-aminopentanoate + lipoate  D-proline + dihydrolipoate

Thus, the two substrates of this enzyme are 5-aminopentanoate and lipoate, whereas its two products are D-proline and dihydrolipoate.

This enzyme belongs to the family of oxidoreductases, specifically those acting on X-H and Y-H to form an X-Y bond with a disulfide as acceptor.  The systematic name of this enzyme class is 5-aminopentanoate:lipoate oxidoreductase (cyclizing). This enzyme participates in arginine and proline metabolism.  It employs one cofactor, pyruvate.

Arginine and proline metabolism
Arginine and proline metabolism is one of the central pathways for the biosynthesis of the amino acids arginine and proline from glutamate. The pathways linking arginine, glutamate, and proline are bidirectional. Thus, the net utilization or production of these amino acids is highly dependent on cell type and developmental stage.
Altered proline metabolism has been linked to metastasis formation in breast cancer.
Ceaux-en-Couhé
Ceaux-en-Couhé (French pronunciation: [so ɑ̃ ku.e]) is a former commune in the Vienne department in the Nouvelle-Aquitaine region in western France. On 1 January 2019, it was merged into the new commune Valence-en-Poitou.

Vienne (department)
Vienne (French pronunciation: [vjɛn] ⓘ vyen; Poitevin-Saintongeais: Viéne) is a landlocked department in the French region of Nouvelle-Aquitaine. It takes its name from the river Vienne. It had a population of 438,435 in 2019.
Trouble in Paradise (TV series)
Trouble in Paradise is an Australian television documentary series on the Nine Network which first aired at 8:30 pm on Thursday, 25 June 2009. The series is narrated by journalist Liam Bartlett and actress Brooke Satchwell, and chronicles the harrowing experiences of Australians travelling on their holidays.

Trouble in Paradise features six edited stories from a similar British series, named My Holiday Hostage Hell (which is broadcast in Australia on the Crime & Investigation Network), and six originally-produced stories. Each episode consists of two stories, and six episodes have been produced.

The show was axed from the Nine Network's schedule after three of the six episodes had aired. It was eventually returned to the schedule of the Nine Network's digital multichannel, GEM, which broadcast the remaining three episodes commencing 16 March 2011.

Real Crime (Australian TV channel)
Real Crime, formerly known as Crime + Investigation (often shortened to CI) is an Australian pay television channel which focuses on crime, investigation and mystery programming. It is run by Foxtel Management Pty Ltd.

The channel launched on 1 January 2005, replacing the Australian feed of TechTV; it was the first version of C+I worldwide, with the American flagship launching three months later.. From that date, until 31 July 2024, the programming and name of Crime + Investigation were licensed to Foxtel by A&E Television Networks. On 2 September 2007, the channel became available in New Zealand on Sky, channel 71.

On 1 August 2024, the channel rebranded to Real Crime.

The channel shows a variety of shows dealing with criminal investigations. The content is mostly sourced from overseas except for limited original content such as the popular Crime Investigation Australia hosted by Steve Liebmann focusing on infamous Australian crimes.
Princeton Seminary Chapel
The Princeton Seminary Chapel is the spiritual center of the Princeton Theological Seminary, located in New Jersey, United States, and has been in continuous use since its completion in 1834.  It was built by renowned local architect and builder Charles Steadman in stuccoed brick with a simple Doric portico. As the chapel of the oldest Presbyterian Seminary in the United States, the building has been home to many of the most important Presbyterian theologians, including the great figures of the Princeton Theology.  The narthex has plaques that honor Samuel Miller, after whom the chapel is named, Charles Hodge, Archibald Alexander Hodge, Caspar Wistar Hodge, Sr., and B. B. Warfield.

Charles Hodge
Charles Hodge (December 27, 1797 – June 19, 1878) was a  Presbyterian theologian in the area of reformed theology. He was also principal of Princeton Theological Seminary between 1851 and 1878.

He was a leading exponent of the Princeton Theology, an orthodox Calvinist theological tradition in America during the 19th century. He advocated for the authority of the Bible as the Word of God. Many of his ideas were adopted in the 20th century by Fundamentalists and Evangelicals.
Muthuchippikal
Muthuchippikal is a 1980 Indian Malayalam film, directed by Hariharan and produced by C. Das. The film stars Madhu, Srividya, Hari and Sankaradi in the lead roles. The film has musical score by K. J. Joy.

Srividya
Srividya (24 July 1953 – 19 October 2006), was an Indian actress best known for her work predominantly in Malayalam and Tamil films, along with a few Telugu, Kannada and Hindi films. In a career spanning for 40 years, she had acted in more than 800 films. In the latter part of her career, she concentrated on Malayalam films. In addition to acting, Srividya occasionally worked as a playback singer as well as carnatic singer. She was also a well-trained Bharathanatyam dancer. She was best known for restraint and subtlety in portrayal of varied emotions. She used her own voice for dubbing in almost all movies in all languages. She died in 2006 after battling metastatic breast cancer.
SS Graf Waldersee
SS Graf Waldersee was a transatlantic liner that was launched in Germany in 1898 and spent most of her career with Hamburg America Line (HAPAG). She was the third of a class of four HAPAG sister ships that were built in the United Kingdom and Germany between 1896 and 1899.

In 1919 HAPAG surrendered Graf Waldersee to the United States as part of Germany's World War I reparations to the Allies. She became the United States Navy troop ship USS Graf Waldersee (ID-4040) and was used to repatriate American Expeditionary Forces troops from Europe.

At the end of 1919 Graf Waldersee was transferred from the United States Shipping Board to the UK Shipping Controller. She was scrapped in Germany in 1922.

United States Shipping Board
The United States Shipping Board (USSB) was a corporation established as an emergency agency by the 1916 Shipping Act (39 Stat. 729), on September 7, 1916. The United States Shipping Board's task was to increase the number of US ships supporting the World War I efforts. The program ended on March 2, 1934.
Eleutheros Cooke House (1415 Columbus Avenue, Sandusky, Ohio)
The Eleutheros Cooke House, also known as the Cooke-Dorn House, at 1415 Columbus Avenue in Sandusky, Ohio is a three-story, limestone Greek Revival style house that was built in 1844.  It was the last home of Eleutheros Cooke, one of the first settlers in Sandusky and its first lawyer.  Eleutheros was father of Jay Cooke, the Civil War financier.

It was listed on the National Register of Historic Places in 1982.

The house is owned by the Ohio History Connection and is open seasonally as a historic house museum that has been restored to a 1950s appearance. It is managed locally by the Old House Guild of Sandusky.

Historic house museum
A historic house museum is a house of historic significance that is preserved as a museum. Historic furnishings may be displayed in a way that reflects their original placement and usage in a home. Historic house museums are held to a variety of standards, including those of the International Council of Museums. Houses are transformed into museums for a number of different reasons. For example, the homes of famous writers are frequently turned into writer's home museums to support literary tourism.
Barnes Ratwatte II
Barnes Shelton Carlye Ratwatte II (1918 or 1919–2004) was a Sri Lankan lawyer and judge. He was a former Puisne Justice of the Supreme Court of Ceylon and Public Trustee.

Ratwatte was born to a prominent Radala family, who were descended from Ratwatte Dissawa, Dissawa of Matale, a signatory on behalf of the Sinhalese to the Kandyan Convention of 1815. Born to Barnes Ratwatte Dissawa and Rosalind Mahawelatenne Kumarihamy of Mahawelatenne Walauwa, Balangoda, his eldest sister was Sirimavo Bandaranaike the first female prime minister in the world.

Educated at Trinity College, Kandy, and the Ceylon Law College. He became an Advocate and was appointed as a Magistrate in 1960. In 1974, he was appointed President of the Appeal Court. Later appointed to the Supreme Court of Sri Lanka he retired in 1983.

Advocate
An advocate is a professional in the field of law. Different countries and legal systems use the term with somewhat differing meanings. The broad equivalent in many English law–based jurisdictions could be a barrister or a solicitor. However, in Scottish, Manx, South African, Italian, French, Spanish, Portuguese, Scandinavian, Polish, Israeli, South Asian and South American jurisdictions, "advocate" indicates a lawyer of superior classification.

"Advocate" is in some languages an honorific for lawyers, such as "Adv. Sir Alberico Gentili". "Advocate" also has the everyday meaning of speaking out to help someone else, such as patient advocacy or the support expected from an elected politician; this article does not cover those senses.
Joseph C. Muren
Joseph Carl Muren (February 5, 1936 – July 27, 2009) was a general authority of the Church of Jesus Christ of Latter-day Saints (LDS Church) from 1991 to 1996. He also taught institute classes at Weber State College.  He authored a soft bound book titled "Causes and affects of inactivity in the Church."

General authority
A general authority is a member of the highest levels of leadership within the Church of Jesus Christ of Latter-day Saints who has administrative and ecclesiastical authority over the church. A general authority's jurisdiction is church-wide, in contrast to the responsibilities of a local authority or an area authority, which relate to a particular area, unit, or department of the church. As a group, the general authorities are often referred to as "the Brethren". As of April 2023, the church listed 95 general authorities.
Audio Analytic
Audio Analytic is a British company headquartered in Cambridge, England that has developed a patented sound recognition software framework called ai3, which provides technology with the ability to understand context through sound. This framework includes an embeddable software platform that can react to a range of sounds such as smoke alarms and carbon monoxide alarms, window breakage, infant crying and dogs barking.

Bark (sound)
A bark is a sound most often produced by dogs. Other animals that make this noise include, but are not limited to, wolves, coyotes, foxes, seals, frogs and owls. Bark is also a verb that describes the sound of many canids.
Richmond Raiders
The Richmond Raiders were a professional indoor football team located in Richmond, Virginia the Richmond Coliseum as their home arena. The Raiders began play in the 2010 as an expansion team of the American Indoor Football Association (AIFA). The Raiders moved to the Southern Indoor Football League (SIFL) when the Eastern Division of the AIFA merged with the SIFL in the winter of 2010, beginning SIFL play in the 2011 season. After just a single season in the SIFL the Raiders, along with four other members of the SIFL, became the charter members of the Professional Indoor Football League (PIFL). The team was then a member the PIFL from 2012 to 2015.

Expansion team
An expansion team is a new team in a sports league, usually from a city that has not hosted a team in that league before, formed with the intention of satisfying the demand for a local team from a population in a new area. Sporting leagues also hope that the expansion of their competition will grow the popularity of the sport generally. The term is most commonly used in reference to the North American major professional sports leagues but is applied to sports leagues in other countries with a closed franchise system of league membership. The term refers to the expansion of the sport into new areas. The addition of an expansion team sometimes results in the payment of an expansion fee to the league by the new team and an expansion draft to populate the new roster.
Stephen Birmingham
Stephen Gardner Birmingham (May 28, 1929 – November 15, 2015) was an American author known for his social histories of wealthy American families, often focusing on ethnicity — Jews (his "Jewish trilogy": Our Crowd, The Grandees, The Rest of Us),  African-Americans (Certain People), Irish (Real Lace), and the Anglo-Dutch (America's Secret Aristocracy). He also wrote several novels, also about wealthy people.

Little, Brown and Company
Little, Brown and Company is an American publishing company founded in 1837 by Charles Coffin Little and James Brown in Boston. It publishes works by American authors. Early lists featured Emily Dickinson's poetry and Bartlett's Familiar Quotations. Since 2006, Little, Brown and Company is a division of the Hachette Book Group.
Qiwña Milluku
Qiwña Milluku (Aymara and Quechua qiwña polylepis, Quechua milluku, ulluku a root vegetable, Hispanicized spelling Queuñamilloco) is a mountain in the Andes of Peru, about 5,200 metres (17,060 ft) high. It is situated in the Moquegua Region, Mariscal Nieto Province, Carumas District, and in the Puno Region, El Collao Province, Santa Rosa District. It lies northeast of the mountain Jach'a K'uchu.

Department of Puno
Puno (Spanish pronunciation: [ˈpuno]; Aymara and Quechua: Punu) is a department of Peru. Located in the country's southeast, it is the fifth largest department in Peru, after Cuzco, Madre de Dios, Ucayali, and Loreto. It is bordered by Bolivia to the east, the departments of Madre de Dios to the north, Cusco and Arequipa to the west, Moquegua to the southwest, and Tacna to the south. It is administered by a regional government. Its capital is the city of Puno, which is located on Lake Titicaca in the geographical region known as the Altiplano or high sierra.
Giuseppe Comini
Giuseppe Comini (20 September 1922 – 6 April 2011) was an Italian fencer. He competed in the team sabre event at the 1956 Summer Olympics. He also competed at the 1955 Mediterranean Games where he won a gold medal in the team sabre event.

Sabre (fencing)
The sabre (US English: saber, both pronounced /ˈseɪbər/) is one of the three disciplines of modern fencing alongside foil & epee. The sabre weapon is for thrusting and cutting with both the cutting edge and the back of the blade (unlike the other modern fencing weapons, the épée and foil, where a touch is scored only using the point of the blade).

The informal term sabre fencer refers to sabre fencers of both genders.
Government of Cantabria
The Government of Cantabria is one of the statutory institutions that conform the Autonomous Community of Cantabria. It is the superior collegiate body that directs the politics and the Administration of this Spanish autonomous community, and at the same time the holder of the executive power as well as the regulatory authority over said territory.

Collegial body
Collegial body (or collegiate body, collegial executive, collective executive) is a governmental or organizational entity in which power and authority are vested equally in each of a number of colleagues, rather than in a single individual. This structure is typically contrasted with monocratic authority (bureaucracy), where power is held by a single chief or executive and flows through a hierarchy.

In sociology and political science, collegiality is analyzed both as a historical mechanism for limiting arbitrary power and as a modern structural adaptation in organizations dominated by professionals.
Kerin O'Keefe
Kerin O'Keefe is a wine critic specialized in Italian wine and author of four books. She reviews wines and writes articles on the growing areas, wines and producers for kerinokeefe.com.

O'Keefe was Italian Editor for Wine Enthusiast from May 2013 until June 2022. From 2002 to 2013, she wrote regularly on Italian wine for Decanter and from 2004 for The World of Fine Wine. She was also Contributing Editor for The Wine News from 2003 to 2009.

Wine critic
A wine critic is a person who evaluates wine and describes it either with a numerical rating, a tasting note, or a combination of both. Their critiques, found in books, newspapers, magazines, newsletters, online, or in sales materials for wine, are often used by consumers in the process of deciding whether or not to buy a wine.
Giuseppe Crespi
Giuseppe Maria Crespi (14 March 1665 – 16 July 1747), nicknamed Lo Spagnuolo ("The Spaniard"), was an Italian late Baroque painter of the Bolognese School. His eclectic output includes religious paintings and portraits, but he is now most famous for his genre paintings.

John of Nepomuk
John of Nepomuk (or John Nepomucene) (Czech: Jan Nepomucký; German: Johannes Nepomuk; Latin: Ioannes Nepomucenus) (c. 1345 – 20 March 1393)
was a saint of Bohemia. He was executed by King Wenceslaus IV of Bohemia for disobedience. John was thrown into the Vltava river.

A legend grew that John was executed for refusing to divulge the secrets of the Queen's confession to Wenceslaus. This fiction made John of Nepomuk the martyr of the Seal of the Confessional. He is also a patron against calumnies and a protector from floods and drowning.
Wedding Preparations in the Country
"Wedding Preparations in the Country" (German: "Hochzeitsvorbereitungen auf dem Lande") is an incomplete work by Franz Kafka which depicts in great detail the journey of the groom, Raban, travelling to the country to meet his future wife, Betty. Written between 1907 and 1908, three fragments with missing pages have survived, and, as with most of Kafka's work, they were published after his death by his friend Max Brod. According to Brod, Kafka's intention was to complete the story as a novel. An English translation of the story appears in The Complete Stories of Franz Kafka.

Max Brod
Max Brod (Hebrew: מקס ברוד; 27 May 1884 – 20 December 1968) was an Israeli author, composer and journalist, born as a German-speaking Czech. He is notable for promoting the work of writer Franz Kafka and composer Leoš Janáček.

Although he was a prolific writer in his own right, he is best remembered as the friend and biographer of Franz Kafka. Kafka named Brod as his literary executor, instructing Brod to burn his unpublished work upon his death. Brod refused and had Kafka's works published instead.

In 1939, as the Nazis occupied Prague, he immigrated to Mandatory Palestine, taking with him a suitcase of Kafka's papers, many of them unpublished notes, diaries, and sketches.
Siddick Junction railway station
Siddick Junction railway station was opened by the Cleator and Workington Junction (C&WJR) and London and North Western Railways in 1880 to provide exchange platforms for passengers wishing to change trains from one company's line to the other. A passenger travelling from Maryport to Distington, for example, would change at Siddick Junction. As a purely exchange station - like Dovey Junction and Dukeries Junction elsewhere in the country - the owning companies would not need to provide road or footpath access or ticketing facilities as no passengers were invited to enter or leave the station except by train.

Ten years later, in 1890, the community of Siddick had grown sufficiently to justify upgrading the station to handle the full range of passengers.

The station was officially "Siddick Junction" but Bradshaw referred to it as plain "Siddick".

Newton Abbot
Newton Abbot is a market town and civil parish on the River Teign in the Teignbridge District of Devon, England. Its population was 24,029 in 2011, and was estimated at 26,655 in 2019. It grew rapidly in the Victorian era as the home of the South Devon Railway locomotive works. This later became a major steam engine shed, retained to service British Railways diesel locomotives until 1981. It now houses the Brunel industrial estate. The town has a race course nearby, the most westerly in England, and a country park, Decoy. It is twinned with Besigheim in Germany and Ay in France.
Tyler Staker
Tyler Staker (born c. 1983) is an American college football coach. He is the head football coach for Coe College, a position he has held since 2016. He is the son of former Coe head football coach Steve Staker.

Coe College
Coe College is a private liberal arts college in Cedar Rapids, Iowa, United States. It was founded in 1851 and is affiliated with the Presbyterian Church (USA). The college is a member of the Associated Colleges of the Midwest and the Association of Presbyterian Colleges and Universities.
Synaptic stabilization
Synaptic stabilization is crucial in the developing and adult nervous systems and is considered a result of the late phase of long-term potentiation (LTP). The mechanism involves strengthening and maintaining active synapses through increased expression of cytoskeletal and extracellular matrix elements and postsynaptic scaffold proteins, while pruning less active ones. For example, cell adhesion molecules (CAMs) play a large role in synaptic maintenance and stabilization. Gerald Edelman discovered CAMs and studied their function during development, which showed CAMs are required for cell migration and the formation of the entire nervous system. In the adult nervous system, CAMs play an integral role in synaptic plasticity relating to learning and memory.

Gerald Edelman
Gerald Maurice Edelman (/ˈɛdəlmən/; July 1, 1929 – May 17, 2014) was an American biologist who shared the 1972 Nobel Prize in Physiology or Medicine for work with Rodney Robert Porter on the immune system.  Edelman's Nobel Prize-winning research concerned discovery of the structure of antibody molecules.  In interviews, he has said that the way the components of the immune system evolve over the life of the individual is analogous to the way the components of the brain evolve in a lifetime. There is a continuity in this way between his work on the immune system, for which he won the Nobel Prize, and his later work in neuroscience and in philosophy of mind.
Iraj Shahin-Baher
Iraj Shahin-Baher (Persian: ایرج شهین‌باهر) is an Iranian politician and the fifty-sixth mayor of Tabriz. He was elected by the Islamic City Council of Tabriz in September 2017 and was inaugurated on same year in Saat City Hall. His tenure in Tabriz Municipality ended in 2021.

Sa'at Tower
Sa'at Tower also known as Tabriz Municipality Palace (Persian: کاخ شهرداری تبریز, also Romanized as Sā'at Tower) is a building in Tabriz which is used as the city hall and main office of the municipal government of Tabriz, East Azarbaijan Province, Iran. The Municipality Palace features a hall, a clock tower, and a small garden.
2009–10 synchronized skating season
The 2009–10 synchronized skating season began on July 1, 2009, and ended on June 30, 2010. During this season, which was concurrent with the season for the other four disciplines (men's single, ladies' single, pair skating and ice dancing), elite synchronized skating teams competed on the International Skating Union (ISU) Championship level at the 2010 Senior World Championships and Junior World Challenge Cup. They also competed at various other international as well as national synchronized skating competitions.

Synchronized skating
Synchronized skating, often called synchro, is an ice skating sport where between 8 and 20 skaters perform together as a team. They move as a flowing unit at high speed over the ice, while performing elements and footwork.

This complex sport originated in 1956 and was initially called "precision skating" due to its emphasis on the maintenance of intricate and precise formations and the requirement of precise timing from all members of the group. Synchronized skating is now well-established as an organized sport in several European countries with several of them having produced teams who frequently win championships at the international level. As of 2022, there are more than 600 synchro teams in United States alone.