hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Hepatic porphyria
Hepatic porphyrias is a form of porphyria in which toxic porphyrin molecules build up in the liver. Hepatic porphyrias can result from a number of different enzyme deficiencies.

Examples include (in order of synthesis pathway):

Acute intermittent porphyria

Porphyria cutanea tarda and Hepatoerythropoietic porphyria

Hereditary coproporphyria

Variegate porphyria

Porphyrin
Porphyrins (/ˈpɔːrfərɪns/ POR-fər-ins) are heterocyclic, macrocyclic, organic compounds, composed of four modified pyrrole subunits interconnected at their α carbon atoms via methine bridges (=CH−). In vertebrates, an essential member of the porphyrin group is heme, which is a component of hemoproteins, whose functions include carrying oxygen in the bloodstream. In plants, an essential porphyrin derivative is chlorophyll, which is involved in light harvesting and electron transfer in photosynthesis.

The parent of porphyrins is porphine, a rare chemical compound of exclusively theoretical interest. Substituted porphines are called porphyrins. With a total of 26 π-electrons the porphyrin ring structure is a coordinated aromatic system. One result of the large conjugated system is that porphyrins absorb strongly in the visible region of the electromagnetic spectrum, i.e. they are deeply colored. The name "porphyrin" derives from Greek  πορφύρα (porphyra) 'purple'.
3DISCO
3DISCO (stands for "3D imaging of solvent-cleared organs") is a histological method that make biological samples more transparent (so called "cleared") by using series of organic solvents for matching the refractive index (RI) of the tissues with that of the surrounding medium.  Structures in transparent tissues can be examined by fluorescence microscopy, without the need for time-consuming physical sectioning and subsequent reconstruction in silico.

The method was developed by the team of Ali Ertürk and Hans-Ulrich Dodt at the Max-Planck-Institute in Munich, and it was aimed primarily at clearing and imaging unsectioned mouse brain and spinal cord samples. Later on, the original method or modified versions of it were successfully used in many fields of biological research to  image and investigate whole body of mice, structure and function within the mouse brain, stem cells, tumor tissues, developmental processes, or whole human embryos.

Histology
Histology, also known as microscopic anatomy, microanatomy or histoanatomy, is the branch of biology that studies the microscopic anatomy of biological tissues. Histology is the microscopic counterpart to gross anatomy, which looks at larger structures visible without a microscope.

Historically, microscopic anatomy was divided into organology, the study of organs, histology, the study of tissues, and cytology, the study of cells, although modern usage places all of these topics under the field of histology. In medicine, histopathology is the branch of histology that includes the microscopic identification and study of diseased tissue. In the field of paleontology, the term paleohistology refers to the histology of fossil organisms.
Héctor Herrera
Héctor Miguel Herrera López (Spanish pronunciation: [ˈeɣtoɾ eˈreɾa]; born 19 April 1990) is a Mexican professional footballer who plays as midfielder for Major League Soccer club Houston Dynamo.

Herrera made his professional debut with Pachuca, spending three years at the club before transferring to Portuguese side Porto. Over a six-year spell with Porto, he made more than 200 appearances across all competitions and won a Primeira Liga title. He subsequently joined Atlético Madrid, where he captured a La Liga championship, before later playing for Houston Dynamo and Toluca.

On the international stage, Herrera made over 100 appearances for the national team. He represented Mexico at the FIFA World Cup in 2014, 2018 and 2022, and at the 2012 Summer Olympics in London, where he became a gold medalist.

CONCACAF Gold Cup
The CONCACAF Gold Cup (Spanish: Copa Oro CONCACAF) is an association football  competition organized by CONCACAF as its premier continental tournament for men's senior national teams from North America, Central America and the Caribbean. The tournament is held every two years with its inaugural edition in 1991. It is the direct successor competition of the CONCACAF Championship (1963–1989).

So far, three national teams have won the tournament: Mexico (10 times), the United States (7), and Canada (1). All of them are member associations of the North American Football Union (NAFU).
Kristin Schirmer
Kristin Schirmer (born 1967) is a German cell biologist and toxicologist. She is the Head of Department of Environmental Toxicology at the Swiss Federal Institute of Aquatic Science and Technology (Eawag)] and also a professor at the Swiss Federal Institute of Technology in Lausanne (EPFL) and ETH Zurich. Schirmer specializes in Molecular and Cellular Mechanisms of Toxicity, Aquatic Organisms, Chemical Hazard Assessment, Adverse Outcome Pathways, in vitro Alternatives to Animal Testing, Fish Cell Lines and Biomonitoring.

Helmholtz Centre for Environmental Research
The work of the Helmholtz Centre for Environmental Research – UFZ (prior to 28 November 2006 UFZ-Umweltforschungszentrum Leipzig-Halle GmbH) covers both basic research and applied research.

The UFZ was established on 12 December 1991. The Centre commenced its research activities on 2 January 1992. The UFZ has locations in Leipzig, Halle and Magdeburg in Germany. In addition, it operates an experimental station in Bad Lauchstädt. The UFZ employs a total of about 1,259 employees (as of December 2024).

The UFZ has been operating KUBUS, a modern communications and event venue in Leipzig, since 2004. KUBUS has flexible event spaces in a range of sizes and accommodates up to 550 people.
Adam Berry
Adam Barrett Berry  (born December 3, 1966) is a two-time American Emmy Award-winning television and film composer and a Grammy Award-winning producer and member of the new age band White Sun. He is originally from Los Angeles. Some of his credits include South Park, Kim Possible, American Dragon: Jake Long, Buzz Lightyear of Star Command, Penguins of Madagascar, Big Hero 6: The Series, and The Sarah Silverman Program. He worked closely with Trey Parker and Matt Stone's in developing the scores for the first four seasons of South Park, and also played in their punk band, DVDA. As a member of White Sun, Berry garnered a Grammy Award for best New Age album in 2017 for the album White Sun II.

The Sarah Silverman Program
The Sarah Silverman Program (stylized as The Sarah Silverman Program.) is an American television sitcom which ran from February 1, 2007, to April 15, 2010, on Comedy Central starring comedian and actress Sarah Silverman, who created the series with Dan Harmon and Rob Schrab. The Sarah Silverman Program faced cancellation in 2009 when Comedy Central and the producers were unable to reach an agreement for the show's per-episode budget. LGBT-interest cable channel Logo stepped in to co-produce the third season.
Adolf Joszt
Adolf Joszt (Polish pronunciation: [a.dɔlf jɔʂt]; born 1889 in Lviv - 1957 in Gliwice) was a Polish chemist, considered to be a significant precursor to the practices of biotechnology and environmental protection.

Environmental protection
Environmental protection, or environment protection, refers to the taking of measures to protecting the natural environment, prevent pollution and maintain ecological balance. Action may be taken by individuals, advocacy groups and governments. Objectives include the conservation of the existing natural environment and natural resources and, when possible, repair of damage and reversal of harmful trends.

Due to the pressures of overconsumption, population growth and technology, the biophysical environment is being degraded, sometimes permanently. This has been recognized, and governments have begun placing restraints on activities that cause environmental degradation. Since the 1960s, environmental movements have created more awareness of the multiple environmental problems. There is disagreement on the extent of the environmental impact of human activity, so protection measures are occasionally debated.
John Apparao 40 Plus
John Apparao 40 Plus is a 2008 Indian Telugu film starring Krishna Bhagavan and Simran with Jeeva, Shankar Melkote, Satyam Rajesh and Vasu Inturi in supporting roles. The film was theatrically released on 20 March 2008.

Satyam Rajesh
Rajesh Babu, better known as Satyam Rajesh, is an Indian actor who primarily appears in Telugu films. He has worked in more than 350 films. Rajesh got the moniker 'Satyam' following his appearance in the 2003 film of the same name.
2024 Finneidfjord train derailment
The 2024 Finneidfjord train derailment was a train accident on the Nordland Line that took place on 24 October 2024. The accident took place between Bjerka Station and Finneidfjord and led to the death of the train driver and the injury of four passengers. The train was carrying 46 passengers, plus 3 staff members, adding up to a total of 49 souls on board.

Both European route E6 and Nordland Line were closed as a result of the accident. With the E6 being the only continuous road and the Nordland Line the only railway line in northern Norway, the country was essentially cut in two. The removal of the train was completed on 5 November 2024, with the E6 being reopened the following day. Nordland Line was reopened on 30 November 2024.

European route E12
European route E12 is a road that is part of the International E-road network. It begins in Mo i Rana, Norway, transverses Sweden and ends in Helsinki, Finland, with a ferry line between Sweden and Finland. The part within Finland is Finnish national highway 3. The road is about 910 kilometres (570 miles) in length.

The ferry service between Holmsund and Vaasa is operated by Wasa Line using the M/S Aurora Botnia, with up to two daily departures in each direction taking about three and a half hours.

A road bridge, known as the Kvarken Bridge has been proposed by parties on both sides of the Gulf, along which the E12 could continue without ferry connections. No commitment has been made to build such a fixed link.
Homero Díaz Rodríguez
Homero Díaz Rodríguez (born 12 April 1959) is a Mexican politician affiliated with the Institutional Revolutionary Party. As of 2014 he served as Deputy of the LIX Legislature of the Mexican Congress as a plurinominal representative.

LIX Legislature of the Mexican Congress
The LIX Legislature (59th session) of the Congress of Mexico met from September 2003 to August 2006. All members of the lower house (Chamber of Deputies) were elected in the elections of July 2003 while members of the upper house (Senate) were elected in the elections of July 2000.
Snowmass (ski area)
Snowmass is a ski resort located in the Town of Snowmass Village near Aspen, Colorado.   The ski area is owned and operated by the Aspen Skiing Company as part of the  Aspen/Snowmass complex. It was opened on December 17, 1967.

Ski resort
A ski resort is a resort developed for skiing, snowboarding, and other winter sports. In Europe, most ski resorts are towns or villages in or adjacent to a ski area–a mountainous area with pistes (ski trails) and a ski lift system. In North America, it is more common for ski areas to exist well away from towns, so ski resorts usually are destination resorts, often purpose-built and self-contained, where skiing is the main activity.
Christoph Schlagbauer
Christoph Schlagbauer (born 11 September 1989) is an Austrian professional triathlete. His biggest achievement is from the period as an AgeGrouper, when he won the Silver Medal at the 2013 Ironman World Championship AgeGroup M18.

2013 Ironman World Championship
The 2013 Ironman World Championship was a long distance triathlon competition that was held on October 12, 2013 in Kailua-Kona, Hawaii. The event was won by Belgium's Frederik Van Lierde and Australia's Mirinda Carfrae. It was the 37th edition of the Ironman World Championship, which has been held annually in Hawaii since 1978. The championship is organized by the World Triathlon Corporation (WTC).
1972–73 Harty Cup
The 1972–73 Harty Cup was the 53rd staging of the Harty Cup since its establishment by the Munster Council of the Gaelic Athletic Association in 1918. The competition ran from 15 October 1972 to 11 March 1973. A change in format saw the winners of the B-grade Corn Phádraig enter at the semi-final stage.

St Finbarr's College successfully defended its title in the Harty Cup final, 5–14 to 2–05, on 11 March 1973 at Dr Mannix Sportsfield in Charleville, against Cashel CBS. It was their first meeting in the final and St Finbarr's College fifth successive Harty Cup title overall and a third consecutive title.

St Finbarr's College's Tadhg Murphy was the top scorer with 7-05.

1971–72 Harty Cup
The 1971–72 Harty Cup was the 52nd staging of the Harty Cup since the establishment of the hurling competition by the Munster Council of the Gaelic Athletic Association in 1918. The draw for the opening round fixtures took place on 18 September 1971. The competition ran from 6 October 1971 to 19 March 1972.

St Finbarr's College successfully defended its title at the Harty Cup final 6–11 to 2–07 played on 19 March 1972 at Dr Mannix Sportsfield in Charleville, against St Flannan's College. It was their third overall meeting in a final and a rematch from the previous year. It was St Finbarr's College's fourth overall Harty Cup title and first consecutive two year set titles.

St Finbarr's College's Tom Fogarty was the top scorer with 3–16.
Maria Luigia Borsi
Maria Luigia Borsi (born 1973) is an Italian opera singer. A lyric soprano, she is especially known for interpreting operas by Giacomo Puccini and Giuseppe Verdi. Among the qualities noted by the critical press are her breath control, phrasing, rich tone, and acting ability.

Lorin Maazel
Lorin Varencove Maazel (/məˈzɛl/; March 6, 1930 – July 13, 2014) was an American conductor, violinist and composer. He began conducting at the age of eight and by 1953 had decided to pursue a career in music. He had established a reputation in the concert halls of Europe by 1960 but his career in the U.S. progressed far more slowly. He served as music director of The Cleveland Orchestra, Orchestre National de France, Pittsburgh Symphony Orchestra, Bavarian Radio Symphony Orchestra, and the New York Philharmonic, among other posts. Maazel was well regarded in baton technique and had a photographic memory for scores. Described as mercurial and forbidding in rehearsal, he mellowed in old age.
The Square Ring (play)
The Square Ring is a 1952 play by Ralph Peterson. It premiered at the Theatre Royal, Brighton before transferring to the Lyric Theatre in Hammersmith where it ran for 39 performances between 21 October and 22 November 1952. The Lyric cast featured Liam Redmond, John Moffatt, Rex Garner, Ronald Lewis, Bill Owen, John Colicos, Bill Travers, George Rose, Peter Bayliss, Duncan Lamont, Hugh Goldie and Harry Towb.

Duncan Lamont
Duncan William Ferguson Lamont (17 June 1918 – 19 December 1978) was a British actor. Born in Lisbon, Portugal, and brought up in Scotland, he had a long and successful career in film and television, appearing in a variety of high-profile productions.
Mannavanur
Mannavanur (Mannavanor, Mannavannur), is a farming village of 1437 households in Mannavanor Panchayat, Dindigul district, Tamil Nadu, India, 35 kilometres (22 mi) west from Kodaikanal
It is 7 kilometres (4 mi) by road from Kumbur village and 9 kilometres (6 mi) from Kilanavayal village.  Altitude is 1,880 metres (6,170 ft).

Kodaikanal
Kodaikanal (ko-DYE-KAH-null, Tamil pronunciation: [ko'ɖaɪ'kaːnəl]) is a municipality and hill station in Dindigul district in the state of Tamil Nadu, India. It is situated at an altitude of 2,225 m (7,300 ft) in the Palani Hills of the Western Ghats. Kodaikanal was established in 1845 to serve as a refuge from the high temperatures and tropical diseases during the summer in the plains. It is a popular tourist destination and is referred to as the "Princess of Hill stations" with much of the local economy is based on the hospitality industry serving tourism. As per the 2011 census, the city had a population of 36,501.
Matt Lambros
Matthew Lambros (born February 8, 1985) is a Canadian former professional football wide receiver who played in the Canadian Football League (CFL). He was selected by the Toronto Argonauts in the second round of the 2009 CFL draft. He played college football for the Liberty Flames.  He was also a member of the Montreal Alouettes.

2009 CFL draft
The 2009 CFL draft took place on Saturday, May 2, 2009 at 11:00 AM ET on TSN. 48 players were chosen from among 774 eligible players from Canadian universities across the country, as well as Canadian players playing in the NCAA. Of the 48 draft selections, 38 players were drafted from Canadian Interuniversity Sport institutions, including the first seven.

The first two rounds were broadcast live on TSN with CFL Commissioner Mark Cohon announcing each selection. The production was hosted by Rod Black and featured the CFL on TSN panel which included Duane Forde, Steve Sumarah, Stefan Ptaszek, Farhan Lalji, Glen Suitor, Matt Dunigan, and Chris Schultz who analyzed the teams' needs and picks.
Jennifer Rupp
Jennifer L. M. Rupp FRSC (born January 27, 1980) is a material scientist and professor at the Technical University of Munich, visiting professor at the Massachusetts Institute of Technology and the CTO for battery research at TUM International Energy Research. Rupp has published more than 130 papers in peer reviewed journals, co-authored 7 book chapters and holds more than 25 patents. Rupp research broadly encompasses solid state materials and cell designs for sustainable batteries, energy conversion and  neuromorphic memory and computing.

Neuromorphic computing
Neuromorphic computing is a computing approach inspired by the human brain's structure and function. It uses artificial neurons to perform computations, mimicking neural systems for tasks such as perception, motor control, and multisensory integration. These systems, implemented in analog, digital, or mixed-mode VLSI, prioritize robustness, adaptability, and learning by emulating the brain’s distributed processing across small computing elements. This interdisciplinary field integrates biology, physics, mathematics, computer science, and electronic engineering to develop systems that emulate the brain’s morphology and computational strategies. Neuromorphic systems aim to enhance energy efficiency and computational power for applications including artificial intelligence, pattern recognition, and sensory processing.
Minnamurra River massacre
On 1 October 1818, approximately six Wodiwodi people were killed in a clash with nine settlers from the Colony of New South Wales along the Minnamurra River in the Illawarra, New South Wales.

The settlers claimed to have been attempting to recover two muskets which had been lent to some of the Aboriginal people which escalated into an armed clash. Local Dapto property owner, William Frederick Weston, his site overseer, Cornelius O'Brien, along with seven unknown convicts and labourers approached an Aboriginal campsite in the early hours of the morning, armed with muskets, swords and knives attached to long sticks. An armed clash resulted.

Dapto, New South Wales
Dapto is a suburb of Wollongong in the Illawarra region of New South Wales, Australia, located on the western side of Lake Illawarra and covering 7.15 square kilometres (2.76 sq mi). As at the 2021 census, the suburb had a population of 10,954.
Benjamin Harris (publisher)
Benjamin Harris (fl. 1673–1716) was an English publisher, a figure of the Popish Plot in England who then moved to New England as an early journalist.  He published the New England Primer, the first textbook in British America, and edited the first multi-page newspaper there, Publick Occurrences Both Foreign and Domestick, from 25 September 1690.

Popish Plot
The Popish Plot was a fictitious conspiracy invented by Titus Oates that between 1678 and 1681 gripped the kingdoms of England and Scotland in anti-Catholic hysteria. Oates alleged that there was an extensive Catholic conspiracy to assassinate Charles II, accusations that led to the show trials and executions of at least 22 men and precipitated the Exclusion Bill Crisis. During this tumultuous period, Oates weaved an intricate web of accusations, fueling public fears and paranoia. However, as time went on, the lack of substantial evidence and inconsistencies in Oates's testimony began to unravel the plot. Eventually, Oates himself was arrested and convicted for perjury, exposing the fabricated nature of the conspiracy.
The Beachcomber (1915 film)
The Beachcomber is a 1915 American drama silent film directed by Phil Rosen and written by Hobart Bosworth. The film stars Hobart Bosworth, Helen Wolcott, Mr. Rahawanaku, Cora Drew, John Weiss and W.F. Harrison. The film was released in 1915, by Paramount Pictures.

Phil Rosen
Philip E. Rosen (May 8, 1888 – October 22, 1951) was an American film director and cinematographer. He directed more than 140 films between 1915 and 1949.

He was born in Marienburg, German Empire (now, Malbork, Poland), grew up in Machias, Maine, and died in Hollywood, California, of a heart attack. He was one of the founders of the American Society of Cinematographers. Rosen was married to model and actress Joyzelle Joyner.

Rosen was meant to direct The Mad Dog of Europe, a film written by Herman J. Mankiewicz with Rudolph Hitler as its central character, but the film was never made.
N,O-Dimethyl-4-(2-naphthyl)piperidine-3-carboxylate
N,O-Dimethyl-4β-(2-naphthyl)piperidine-3β-carboxylate (DMNPC) is a piperidine based stimulant drug which is synthesised from arecoline. It is similar to nocaine in chemical structure, and has two and a half times more activity than cocaine as a dopamine reuptake inhibitor. However it is also a potent serotonin reuptake inhibitor, with similar affinity to fluoxetine. DMNPC racemate has been sold online as a designer drug since late 2024.

DMNPC has four stereoisomers, each of which has different binding affinities, with the 3S,4S enantiomer having the highest overall activity. The 3R,4S enantiomer demonstrates the highest selectivity for 5-HTT.

In animal studies, DMNPC exhibits similar potency as fluoxetine, but with greater activity for DAT and NET. N-Demethylation of DMNPC has shown to produce a 3-fold increase in potency for 5-HTT.

Piperidine
Piperidine is an organic compound with the molecular formula (CH2)5NH. This heterocyclic amine consists of a six-membered ring containing five methylene bridges (–CH2–) and one amine bridge (–NH–). It is a colorless liquid with an odor described as objectionable, human sperm-like, typical of amines. The name comes from the genus name Piper, which is the Latin word for pepper. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as naturally-occurring solenopsins.