hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Contact activation system
In the contact activation system or CAS, three proteins in the blood, factor XII (FXII), prekallikrein (PK) and high molecular weight kininogen (HK), bind to a surface and cause blood coagulation and inflammation. FXII and PK are proteases and HK is a non-enzymatic co-factor. The CAS can activate the kinin–kallikrein system and blood coagulation through its ability to activate multiple downstream proteins. The CAS is initiated when FXII binds to a surface and reciprocal activation of FXII and PK occurs, forming FXIIa and PKa. FXIIa can initiate the coagulation cascade by cleaving and activating factor XI (FXI), which leads to formation of a blood clot. Additionally, the CAS can activate the kinin–kallikrein system when PKa cleaves HK to form cHK, releasing a peptide known as bradykinin (BK). BK and its derivatives bind to bradykinin receptors B1 and B2 to mediate inflammation.

Bradykinin receptor B1
Bradykinin receptor B1 (B1) is a G-protein coupled receptor encoded by the BDKRB1 gene in humans. Its principal ligand is bradykinin, a 9 amino acid peptide generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. The B1 receptor is one of two of G protein-coupled receptors that have been found which bind bradykinin and mediate responses to these pathophysiologic conditions.

B1 protein is synthesized de novo following tissue injury and receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses.

Classical agonist of this receptor includes bradykinin1-8 (bradykinin with the first 8 amino acid) and antagonist includes [Leu8]-bradykinin1-8.
Mischief (1985 film)
Mischief is a 1985 American comedy film starring Doug McKeon, Chris Nash, Catherine Mary Stewart and Kelly Preston. The film was directed by Mel Damski and written by Noel Black. The original music score was composed by Barry De Vorzon.

Set in Nelsonville, Ohio, in 1956, its soundtrack features many popular songs from the era.

Barry De Vorzon
Barry De Vorzon (born July 31, 1934) is an American composer, singer, songwriter, and record producer. He worked as a pop musician during the 1960s and co-founded Valiant Records, before being known as a composer of film and television scores during the following decades. He is a Grammy Award winner, an Academy Award nominee, and a six-time Daytime Emmy Award winner.
2024 Washington Attorney General election
The 2024 Washington attorney general election was held on November 5, 2024, to elect the next attorney general of Washington, concurrently with the 2024 U.S. presidential election, as well as elections to the U.S. Senate and various state and local elections, including for U.S. House and governor of Washington. Incumbent Democratic attorney general Bob Ferguson was eligible to seek re-election to a fourth term but had chosen instead to run successfully for governor. U.S. attorney Nick Brown, a Democrat, won the election against Pasco mayor Pete Serrano, a Republican.

Noah Purcell
Noah Guzzo Purcell (born 1980) is an American attorney serving as the solicitor general of the U.S. state of Washington. He gained national attention when he halted President Donald Trump's first travel ban with a successful lawsuit on behalf of the State of Washington in Washington v. Trump.
Kubus (brand)
Kubus (Polish: Kubuś [ˈku.buɕ]), also known as Kubie in South Africa, is a brand of juice producer, owned by Maspex, and based in Poland. It produces fruit and vegetable juices, drinks, mousses, bottled water, cookies, and others. Its production line is based in Olsztynek, while bottling company in Tychy, both located in Poland.

The company is the leading producer of puree juices in countries of Poland, Romania, Russia, Bulgaria, Hungary, Lithuania, Czechia, Slovakia, and others. It has been noted on the Rzeczpospolita Ranking of the Most Valuable Brands.

Mousse
A mousse (/ˈmuːs/, French: [mus]; lit. 'foam') is a soft, prepared food that incorporates air bubbles to give it a light and airy texture. Depending on preparation techniques, it can range from light and fluffy to creamy and thick. A mousse may be sweet or savory.
Relax, Take It Easy
"Relax, Take It Easy" is the debut single by British singer-songwriter Mika, from his debut album Life in Cartoon Motion. In the UK, it failed to chart upon its original release in October 2006, but after "Grace Kelly" topped the charts in January 2007, it managed to peak at number 67 on the UK Downloads Chart because of download sales.

The song makes use of a melody line from the Cutting Crew hit single "(I Just) Died in Your Arms". In North America, it was released as the third single from the album. The song was released as Mika's sixth single in the UK in stores on 31 December 2007, and for digital download on 24 December 2007 as a double A-side with "Lollipop". This single peaked at number 18 on the UK Singles Chart. The song was also featured prominently in the movie Were the World Mine. It is also in the 2011 film Monte Carlo.

Monte Carlo (2011 film)
Monte Carlo is a 2011 American adventure-romantic comedy film based on the 2001 novel Headhunters by Rankin/Bass co-founder Jules Bass. It was directed by Thomas Bezucha. Denise Di Novi, Alison Greenspan, Nicole Kidman, and Arnon Milchan produced the film for Fox 2000 Pictures and Regency Enterprises. It began production in Harghita, Romania on May 5, 2010. Monte Carlo stars Selena Gomez, Leighton Meester and Katie Cassidy as three friends posing as wealthy socialites in Monte Carlo, Monaco. The film was released on July 1, 2011. It features the song "Who Says" by Selena Gomez & the Scene (whose album When the Sun Goes Down which included the song, was released 3 days before the film's release) and numerous songs by British singer Mika. Monte Carlo received mixed reviews from critics, but earned $39.7 million on a $20 million budget. Fox Home Entertainment released Monte Carlo on DVD and Blu-ray Disc on October 18, 2011.
Máel Ísu II (bishop of the Scots)
Máel Ísu II is the sixth alleged Bishop of the Scots, equivalent to latter day St. Andrews. He is mentioned in the bishop-lists of the 15th-century historians Walter Bower and Andrew of Wyntoun as the successor of Cellach II. We have no direct dates for Máel Ísu II's episcopate, but the indirect evidence for his predecessors suggests that he was bishop in the late 10th and/or early 11th century.

Archbishop of St Andrews
The Bishop of St. Andrews (Scottish Gaelic: Easbaig Chill Rìmhinn, Scots: Beeshop o Saunt Andras) was the ecclesiastical head of the Diocese of St Andrews in the Catholic Church and then, from 14 August 1472, as Archbishop of St Andrews (Scottish Gaelic: Àrd-easbaig Chill Rìmhinn), the Archdiocese of St Andrews.

The name St Andrews is not the town or church's original name. Originally it was Cellrígmonaid ("church of the king's mounth" hence Cill Rìmhinn) located at Cennrígmonaid ("head of the king's mounth"); hence the town became Kilrymont (i.e. Cellrígmonaid) in the non-Gaelic orthography of the High Middle Ages. Today St Andrews has replaced both Kilrymont (and variants) as well as the older English term Anderston as the name of the town and bishopric.

The bishopric itself appears to originate in the period 700–900. By the 11th century, it is clear that it was the most important bishopric in Scotland.
Kadoorie Hill
Kadoorie Hill (Chinese: 加多利山) is an upper class residential area in Kowloon City District, Hong Kong, located south of Kowloon Tong and north of Ho Man Tin.

The majority of the development has its ownership under the Kadoorie family; in 2019 the majority of residential properties are residential properties, something Christopher DeWolf characterises as out of the ordinary for an upper class neighbourhood.

Kadoorie family
The Kadoorie family (Hebrew: כדורי, Arabic: خضوري, Judeo-Arabic: כצׄורי) is a wealthy Hong Kong-based family, originally Jews from Baghdad in Iraq. From the mid-18th century, the family was established in Mumbai (then known as Bombay), becoming one of the wealthiest families in Asia. Their businesses were subsequently centered in Shanghai from the mid-19th century, and then in Hong Kong from the 20th century onwards. The Kadoorie family has been described as the wealthiest non-ethnic Chinese family in Hong Kong.
Sutton Pools
Sutton Pools are a picturesque backwater formed by a number of weirs, islands, footbridges and barriers on the course of the River Thames at Sutton Courtenay, Oxfordshire, England. The higher level of the river is separated from the lower pools by a causeway which dates from Saxon times. This river stretch ceased to be the main navigable route after Culham Cut was constructed in the early 19th century, which also created an island to the north of the Pools. In addition there are three smaller islands, linked by footbridges over the weirs, part of a footpath between Sutton Courtenay and the village of Culham.

The upper river channel at Sutton Pools used to pass beneath a paper mill, though this closed in 1897 and has been demolished. The river route is blocked by a fence here as it passes through the gardens of Mill House. A wooden footbridge and kissing gate lead to the main village.

Culham
Culham is a village and civil parish in a bend of the River Thames, 1 mile (1.6 km) south of Abingdon in Oxfordshire. The parish includes Culham Science Centre and Europa School UK (formerly the European School, Culham, which was the only Accredited European School within the United Kingdom). The parish is bounded by the Thames to the north, west and south, and by present and former field boundaries to the east. It is low-lying and fairly flat, rising from the Thames floodplain in the south to a north-facing escarpment in the north up to 260 feet (80 m) above sea level. The 2011 Census recorded its population as 453.
Kanthi railway station
Kanthi railway station is a railway station on the Tamluk–Digha branch line of South Eastern Railway zone of Indian Railways. The railway station is situated beside Kanthi Bypass Road at Contai in Purba Medinipur district in the Indian state of West Bengal. The distance between Howrah and this railway station is approximately 152 km. Number of Express and passengers trains stop at Kanthi railway station.

South Eastern Railway zone
The South Eastern Railway (abbreviated SER) is one of the 19 railway zones in India. It is headquartered at Garden Reach, Kolkata, West Bengal, India. It comprises Adra railway division, Chakradharpur railway division, Kharagpur railway division and Ranchi railway division.
Louka Katseli
Louka Katseli (Greek: Λούκα Κατσέλη, pronounced [ˈluka kaˈtseli]; born 20 April 1952) is a Greek politician and economist. She is Professor Emerita at the National and Kapodistrian University of Athens. She served as chair of the National Bank of Greece from 2015 to 2016, as Minister for Economy, Competitiveness and Shipping from 2009 to 2010 and as Minister of Labour and Social Security from 2010 to 2011.
In January 2025 she was proposed as a candidate for the Greek Presidency in the 2025 Greek presidential election with the support of Syriza.

Ministry of Labour and Social Security (Greece)
The Ministry of Labour and  Social Security (Greek: Υπουργείο Εργασίας και Κοινωνικής Ασφάλισης) is a government department of Greece. The Ministry is responsible for the labour market, employment, and social security.

Its current name was given in June 2023 when the second government of Kyriakos Mitsotakis renamed the "Ministry of Labour and Social Affairs" to the "Ministry of Labour and Social Security".

The incumbent minister is Niki Kerameus.
Margulis
Margulis is a surname that, like its variants, is derived from the Ashkenazi Hebrew pronunciation of the Hebrew word Margalit (מרגלית, Israeli Hebrew: [maʁɡaˈlit])), meaning 'pearl.' Notable people and characters with the name include:

Berl Broder (born Margulis; 1817–1868), Broder singer

Dan Margulis (born 1951), author, expert on color correction and image retouching

David Margulis, Hero of the Soviet Union

Evgeny Margulis (born 1955), Russian musician

Grigory Margulis (born 1946), Russian mathematician, known for the Margulis lemma

Lynn Margulis (1938–2011), American evolutionary biologist

Margulis, a villain from the game series Xenosaga

Evgeny Margulis
Evgeny Shulimovich Margulis (Russian: Евге́ний Шу́лимович Маргу́лис; (born 25 December 1955) is a Russian rock and blues musician. He was a member of the bands Mashina Vremeni (1975–1979, 1990–2012) and Voskreseniye (1979–1980, 1994–2003), but currently performs independently.
René van Rijswijk
René van Rijswijk (born 3 January 1971) is a Dutch former footballer who played as a forward for RKC, Cambuur and NEC.

He was known for his distinctive appearance, notably his long hair worn in a ponytail, and for his unusually low goalscoring output for a striker, which earned him the nickname De spits zonder doelpunten ("the striker without goals"). He was also known for his relatively low goalscoring output, which earned him the nickname "De spits zonder doelpunten" ("The striker without goals").

NEC Nijmegen
NEC Nijmegen (Nijmegen Eendracht Combinatie), commonly known as NEC (Dutch pronunciation: [ɛneːˈseː]), is a professional Dutch association football club based in Nijmegen. The club currently competes in the Eredivisie, the top tier of Dutch football, following promotion from the 2020–21 Eerste Divisie.

The club has reached the final of the KNVB Cup on five occasions – in 1973, 1983, 1994, 2000 and 2024 – but has never won the cup.
Mahendra of Dakshina Kosala
Mahendra was a king of Dakshina Kosala, whose identity is not completely verified, and is mentioned as a king of Dakshinapatha or Southern India. He was one of the many kings who were subjugated, captured and later released by the powerful Gupta emperor Samudragupta on his Dakshinapatha (Southern India) campaign. Mahendra of Kosala was one of the southern kings of Dakshinapatha paying allegiance and tribute to Samudragupta. His dynasty is uncertain, though some historians suggest that he was from the Kosala branch of the Mahameghavahana dynasty. This branch of the Mahameghavahana dynasty is often identified with the Meghas of Kosala, who ruled over Kosala from the 3rd century AD to the 6th century AD.

Other theories suggest that he was a king of a branch the Ikshvaku dynasty, who had established a mighty kingdom in the south. Yet another theory identifies Mahendra with a Nala king named Mahendraditya.

Andhra Ikshvaku
The Ikshvaku dynasty (IAST: Ikṣvāku) ruled in the eastern Krishna River valley of India, from their capital at Vijayapuri (modern Nagarjunakonda in Andhra Pradesh) for over a century during 3rd and 4th centuries CE. The Ikshvakus are also known as the Andhra Ikshvakus or the Ikshvakus of Vijayapuri to distinguish them from their legendary namesakes: the Ikshvakus of Kosala.

The Ikshvaku kings were Shaivites and performed Vedic rites, but Buddhism also flourished during their reign. Several Ikshvaku queens and princes contributed to the construction of the Buddhist monuments at present-day Nagarjunakonda.
Cainnear (name)
Cainnear is a female Irish given name. Potentially deriving from caoin and der, meaning "gentle daughter", it is the name of one of the legendary daughters of Queen Medb of Connacht and several Irish saints. Variants of the name include Canair, Cainder, and Cainner, and at least two early Christian saints have borne these variants.

Irish name
A formal Irish name consists of a given name and a surname. In the Irish language, most surnames are patronymic surnames (distinct from patronyms, which are seen in Icelandic names for example). The form of a surname varies according to whether its bearer is a man, a woman, or a woman married to a man, who adopts his surname.

An alternative traditional naming convention consists of the first name followed by a double patronym, usually with the father and grandfather's names. This convention is not used for official purposes but is generalized in Gaeltachtaí (Irish-speaking areas) and also survives in some rural non-Gaeltacht areas. Sometimes the name of the mother or grandmother may be used instead of the father or grandfather.
Onraita/Erroeta
Onraita (Spanish pronunciation: [onˈrajta]) or Erroeta (Basque pronunciation: [eroeta]) is a hamlet and concejo located in the municipality of Arraia-Maeztu, Álava, Basque Country, Spain. It is the highest settlement in the province of Álava.

Álava
Álava (Spanish: [ˈalaβa]) or Araba (Basque pronunciation: [aˈɾaba]), officially Araba/Álava, is a province of Spain and a historical territory of the Basque Country, heir of the ancient Lordship of Álava, former medieval Catholic bishopric and now Latin titular see.

Its capital city, Vitoria-Gasteiz, is also the seat of the political main institutions of the Basque Autonomous Community. It borders the Basque provinces of Biscay and Gipuzkoa to the north, the community of La Rioja to the south, the province of Burgos (in the community of Castile and León) to the west and the community of Navarre to the east. The Enclave of Treviño, surrounded by Alavese territory, is however part of the province of Burgos, thus belonging to the autonomous community of Castile and León, not Álava.

It is the largest of the three provinces in the Basque Autonomous Community in geographical terms, with 3,037 km2, but also the least populated with 331,700 inhabitants (2019).
Cornman: American Vegetable Hero
Cornman: American Vegetable Hero a.k.a. Cornman II: The Day of the Locusts is an American cult movie first released in March 2001 by WorldWide International Picture Studios, known for producing low budget B-movies with campy concepts. The film premiered at the South by Southwest Film Festival on March 10, 2001. The film was directed by Barak Epstein and starred Mike Wiebe and James Hoke. The film is a homage/parody of superhero films.

Superhero film
The superhero film is a film genre categorized by the presence of superhero characters, individuals with extraordinary abilities who are dedicated to fighting crime, saving the world, or helping the innocent. It is sometimes considered a sub-genre of the action film genre and has evolved into one of the most financially successful film genres worldwide. These films focus on superhuman abilities, advanced technology, mystical phenomena, or exceptional physical and mental skills that enable these heroes to fight for the common good or defeat a supervillain antagonist.

Superhero films typically include genre elements of romance, comedy, fantasy, and science fiction, with large instances of the superhero genre predominantly occupied and produced by American media franchises DC and Marvel, originally adaptations of their existing works of superhero comic books. Individual superhero films frequently contain a character's origin story.
French ship Aigrette
French ship Aigrette includes the following ships named for aigrette, French for egret:

French frigate Aigrette, a 30-gun frigate launched in 1756

French submarine Aigrette, lead boat of the Aigrette-class submarine, launched in 1904

French submarine Aigrette
Aigrette was the lead boat of the Aigrette-class submarines built for the French Navy between 1902 and 1905. Laid down in May 1902, she was launched in February 1904 and commissioned in 1908. She was essentially an experimental submarine, and although in service during World War I, saw no action. The class was designed by Maxime Laubeuf and used Drzewiecki drop collar launchers and external cradles to launch torpedoes.
Frank Boulton
Frank Forest Boulton is a baseball league founder and the owner of several teams, including the Long Island Ducks. He started the Atlantic League of Professional Baseball in 1998 and was its chief executive officer (CEO).

Boulton graduated from Bay Shore High School in 1969, attended Villanova University and began working in finance. He later bought an interest in the Prince William Cannons, Albany-Colonie Yankees and Wilmington Blue Rocks. He formed the Atlantic League after receiving a call in 1994 from the mayor of Atlantic City, New Jersey seeking his help attracting a professional baseball team to the city.

Bay Shore High School
Bay Shore High School is a public high school located in Bay Shore, New York. The school has about 2,000 students in grades 9 to 12. It is a part of Bay Shore Schools and an International Baccalaureate school.

Graduates of Woodhull School (PK-6) of the Fire Island School District can attend Bay Shore secondary schools, including Bay Shore High School.
2025 South Africa Safari Rally
The 2025 South Africa Safari Rally was a rally raid event based in South Africa. It was the maiden running of the South Africa Safari Rally and was centered around the Sun City Resort.

The event took place from 19 to 24 May 2025 and also counted as the third round of the 2025 World Rally-Raid Championship. The Cars category was won by the Toyota pair of Henk Lategan and Brett Cummings, meanwhile Daniel Sanders won the Bikes class.

Daniel Sanders (motorcyclist)
Daniel Jonathan Sanders (born 30 August 1994) is an Australian professional off-road and rally raid motorcycle racer. Known by the nickname "Chucky", he is most famous for winning the 2025 Dakar Rally and the 2025 World Rally-Raid Championship.
Funabaru Kofun
The Funabaru Kofun (船原古墳)  is a Kofun period burial mound, located in the Taniyama neighborhood of the city of Koga,  Fukuoka Prefecture, Japan. The tumulus was designated a National Historic Site of Japan in 2016.

Kofun
Kofun (古墳; from Sino-Japanese "ancient burial mound") are megalithic tombs or tumuli in Northeast Asia. Kofun were mainly constructed in the Japanese archipelago between the middle of the 3rd century to the early 7th century AD.

The term is the origin of the name of the Kofun period, which indicates the middle 3rd century to early–middle 6th century. Many kofun have distinctive keyhole-shaped mounds (zempō-kōen fun (前方後円墳)). The Mozu-Furuichi kofungun or tumulus clusters were inscribed on the UNESCO World Heritage List in 2019, while Ishibutai Kofun is one of a number in Asuka-Fujiwara residing on the Tentative List.
Bodegas Faustino
The Bodegas Faustino vineyard is located in Spain within the province of Alava in the Basque Country. It is only 5 km (3 miles) from Logroño, the capital of La Rioja, and is included in the Rioja wine-producing region.

Álava
Álava (Spanish: [ˈalaβa]) or Araba (Basque pronunciation: [aˈɾaba]), officially Araba/Álava, is a province of Spain and a historical territory of the Basque Country, heir of the ancient Lordship of Álava, former medieval Catholic bishopric and now Latin titular see.

Its capital city, Vitoria-Gasteiz, is also the seat of the political main institutions of the Basque Autonomous Community. It borders the Basque provinces of Biscay and Gipuzkoa to the north, the community of La Rioja to the south, the province of Burgos (in the community of Castile and León) to the west and the community of Navarre to the east. The Enclave of Treviño, surrounded by Alavese territory, is however part of the province of Burgos, thus belonging to the autonomous community of Castile and León, not Álava.

It is the largest of the three provinces in the Basque Autonomous Community in geographical terms, with 3,037 km2, but also the least populated with 331,700 inhabitants (2019).