hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Ciclindole
Ciclindole (INNTooltip International Nonproprietary Name; developmental code name WIN-27,147-2), also known as cyclindole (USANTooltip United States Adopted Name), is an antipsychotic of the tetrahydrocarbazolamine family with a tricyclic cyclized tryptamine structure that was never marketed.

It displaces spiperone binding in vitro and elevates dopamine levels in the striatum, indicating that it acts as a dopamine D2 receptor antagonist. It also shows apparent affinity for the α1-adrenergic receptor, the serotonin S1 receptor, and the serotonin S2 receptor. However, its affinities for all of the preceding targets are weak, in the low micromolar range.

The related drug flucindole is about 5 to 10 times more potent than ciclindole both in vitro and in vivo.

Alpha-1 adrenergic receptor
The alpha-1 (α1) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gq heterotrimeric G protein. It consists of three highly homologous subtypes, α1A-, α1B-, and α1D-adrenergic. There is no α1C receptor. At one time, there was a subtype known as α1C, but it was found to be identical to the previously discovered α1A receptor subtype. To avoid confusion, naming was continued with the letter D. Catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) signal through the α1-adrenergic receptors in the central and peripheral nervous systems. The crystal structure of the α1B-adrenergic receptor subtype has been determined in complex with the inverse agonist (+)-cyclazosin.
Malacothamnus involucratus
Malacothamnus involucratus is a species of flowering plant in the mallow family known by the common name Carmel Valley bushmallow. It is likely endemic to Monterey County, California, where it is known from Carmel Valley and the Jolon region. A single specimen is attributed to San Luis Obispo County, California but the origin of this specimen is questionable.

Malvaceae
Malvaceae (/mælˈveɪsi.iː, -ˌaɪ/), or the mallows, is a family of flowering plants estimated to contain 244 genera with 4225 known species. Well-known members of economic importance include cacao, cola, cotton, okra, roselle and durian. There are also some genera containing familiar ornamentals, such as Alcea (hollyhock), Malva (mallow), and Tilia (lime or linden tree). The genera with the largest numbers of species include Hibiscus (434 species), Pavonia (291 species), Sida (275 species), Ayenia (216 species), Dombeya (197 species), and Sterculia (181 species).
Malcolm Thomas (basketball, born 1988)
Malcolm Iseiah Thomas (born November 8, 1988) is an American professional basketball player for the Sagesse Club of the Lebanese Basketball League (LBL). He played college basketball for the San Diego State Aztecs, where he twice earned second-team All-Mountain West Conference (MWC) honors.

VTB United League
The VTB United League (Russian: Единая Лига ВТБ) is an international professional men's club basketball league that was founded in 2009. As of the 2025–26 season, it consists exclusively of Russian clubs. Since 2013, it is the first tier of Russian professional club basketball. Therefore, the highest placed Russian team in the league can also be named the Russian national champions. The league is sponsored by Russian state-owned VTB Bank. In 2009 CSKA Moscow won VTB United League Promo-Cup, but this competition does not count as official VTB title. CSKA has dominated the league, having won majority of titles its existence. The VTB United League also holds a youth competition, the VTB United Youth League.
The Artifice (play)
The Artifice is a 1722 comedy by the British writer Susanna Centlivre, first published in 1723. It was her final play, returning to the more robust style of restoration comedy which was very uncommon by this era.

Staged at the Drury Lane Theatre the cast included Robert Wilks as Sir John Freeman, Anne Oldfield as Mrs Watchit, William Wilks as Fainwell, John Mills as Ned Freeman, Benjamin Griffin as Watchit, John Harper as Tally, Christiana Horton as Olivia, Elizabeth Younger as Louisa.

Elizabeth Younger
Elizabeth Younger whose married name was Elizabeth Finch (2 September 1699 – 24 November 1762), was an actress and dancer.

Her sister was the singer and actress Margaret Bicknell. Elizabeth married John Finch, the son of Daniel Finch, 7th Earl of Winchilsea.
Khatib
In Islam, a khatib or khateeb (Arabic: خطيب khaṭīb) is a person who delivers the sermon (khuṭbah) (literally "narration"), during the Friday prayer and Eid prayers.

The khateeb is usually the prayer leader (imam), but the two roles can be played by different people. The khatib should be knowledgeable of how to lead the prayer and be competent in delivering the speech (khutba) however there are no requirements of eligibility to become a khatib beyond being an Adult Muslim. Muslims believe the khatib has to be male, women do not lead Friday prayer.

Khutubah are delivered by men. Edina Leković gave the inaugural speech at the Women's Mosque in California, United States, in 2015.

Edina Leković
Edina Leković is the inaugural Community Scholar in Residence with UCLA's Islamic Studies Program and the Fowler Museum, where is researching and sharing the history of Muslim Los Angeles. She also serves as the Executive Director of the Robert Ellis Simon Foundation, which supports mental wellness services for L.A. County’s most vulnerable residents. Her expertise in storytelling, strategic communications, media relations, leadership development and interfaith community building have been shaped, tested and honed over 25 years of service to advance the cause of American Muslims.
Sibrandahûs
Sibrandahûs (Dutch: Sijbrandahuis) is a small village in the Dantumadiel municipality of Friesland, the Netherlands. It had a population of around 40 in 2017. It is located just west of Dokkum.

Sibrandahûs has no real residential core, the village consists of wide meadows with light habitation and a church placed in a tree seam. The village could also be called a hamlet, but because it has a church and it is the official residential center it is considered a village.

On the corner of the Trekwei and the Burdaarderstrjitwei stands the windmill called Windmotor Sijbrandahuis.

Windmill
A windmill is a machine operated by the force of wind acting on vanes or sails to mill grain (gristmills), pump water, generate electricity, or drive other machinery.
Windmills were used throughout the high medieval and early modern periods; the horizontal or panemone windmill first appeared in Persia during the 9th century, and the vertical windmill first appeared in northwestern Europe in the 12th century. Regarded as an icon of Dutch culture, there are approximately 1,000 windmills in the Netherlands today.
Kayaderossera patent
The Kayaderossera Patent (or Kayaderosseras Patent) was a grant of land made by Anne, Queen of Great Britain in 1701 to thirteen subjects. The patent included 406,000 acres (164,000 ha) comprising most of what is now Saratoga County and parts of Montgomery, Schenectady, and Fulton Counties.

The grantees were Nanning Hermance (or Hermanse, also called Nanning Visscher), Johannes Beekman, Rip Van Dam, Anne Bridges, Johannes Fisher, John Tudor, Javis Hooglandt, John Stephens, John Latham, and Stephen Broughton.

Negotiations with the Mohawks and the French and Indian War delayed the process, and the lands were not surveyed until 1771.  The surveyors divided the patent into twenty five allotments, and each allotment was subdivided into thirteen lots of approximately equal size.  The grantees "drew lots" to determine ownership of individual lots within each allotment.

Rip Van Dam
Rip Van Dam (c. 1660 – 10 June 1749) was an American merchant and colonial administrator who served as the acting governor of New York from 1731 to 1732. As one of the leaders of the republican liberal (or "country") party, Van Dam led confrontations against Governor William Cosby.
Horrible Histories: Frightful First World War (exhibition)
Frightful First World War  was an exhibition that was held at the Imperial War Museum North from 24 May 2008 to 4 January 2009. It was based on the Horrible Histories book of the same name – one of the most popular of the series. It was produced in partnership with Terry Deary and Scholastic Children's books. The exhibition was free.

Scholastic Corporation
Scholastic Corporation is an American multinational publishing, education, and media company that publishes and distributes books, comics, and educational materials for schools, teachers, parents, children, and other educational institutions. Products are distributed via retail and online sales and through schools via reading clubs and book fairs. Clifford the Big Red Dog, a character created by Norman Bridwell in 1963, is the mascot of Scholastic.
GA module
In molecular biology, the GA module, or protein G-related albumin-binding module, is a protein domain which occurs on the surface of numerous Gram-positive bacterial pathogens. Protein G of group C and G Streptococci interacts with the constant region of IgG and with human serum albumin. The GA module is composed of a left-handed three-helix bundle and is found in a range of bacterial cell surface proteins. GA modules may promote bacterial growth and virulence in mammalian hosts by scavenging albumin-bound nutrients and camouflaging the bacteria. Variations in sequence give rise to differences in structure and function between GA modules in different proteins, which could alter pathogenesis and host specificity due to their varied affinities for different species of albumin. Proteins containing a GA module include PAB from Peptostreptococcus magnus.

Alpha helix
An alpha helix (or α-helix) is a sequence of amino acids in a protein that are twisted into a coil (a helix).

The alpha helix is the most common structural arrangement in the secondary structure of proteins. It is also the most extreme type of local structure, and it is the local structure that is most easily predicted from a sequence of amino acids.

The alpha helix has a right-handed helix conformation in which every backbone N−H group hydrogen bonds to the backbone C=O group of the amino acid that is four residues earlier in the protein sequence.
Drumardagh
Drumardagh (Irish: Droim na nArdach) is a townland in the east of County Donegal in Ulster, Ireland. The townland is approximately 5 kilometres (3.1 mi) east of Letterkenny, in the Laggan district of East Donegal, just outside the village of Manorcunningham. The Isle Burn flows along the eastern boundary of the townland. The Irish name, Droim na nArdach, meaning 'ridge of the heights' or 'ridge of the high fields', and it is this elevation that gives the area its views over Lough Swilly, from Glenswilly to Inch Island, and beyond to the peaks of the Fanad and Inishowen peninsulae. Drumardagh townland, which is 330 acres (130 ha) in area, is in the civil parish of Leck in the historical barony of Raphoe North.

Raphoe North
Raphoe North (/ræˈfoʊ/; Irish: Ráth Bhoth Thuaidh), or North Raphoe, is a barony in County Donegal, Ireland. Baronies were mainly cadastral rather than administrative units. They acquired modest local taxation and spending functions in the 19th century before being superseded by the Local Government (Ireland) Act 1898.
It Could Happen to You (1939 film)
It Could Happen to You is a 1939 American comedy film directed by Alfred L. Werker and written by Lou Breslow and Allen Rivkin. The film stars Stuart Erwin, Gloria Stuart, Raymond Walburn, Douglas Fowley, June Gale and Clarence Kolb. The film was released on June 8, 1939, by 20th Century Fox.

Lou Breslow
Lou Breslow (born Lewis Breslow; July 18, 1900 – November 10, 1987) was an American screenwriter and film director. He wrote for 70 films between 1928 and 1955. He also directed seven films between 1932 and 1951 and wrote scripts for both Laurel and Hardy in their first two films at 20th Century Fox, and Abbott and Costello.

Breslow married film actress and comedian Marion Byron in 1932, and remained married until her death in 1985.
1994 Saxony state election
The 1994 Saxony state election was held on 11 September 1994 to elect the members of the 2nd Landtag of Saxony. The incumbent Christian Democratic Union (CDU) government led by Minister-President Kurt Biedenkopf retained its majority and continued in office.

Landtag of Saxony
The Landtag of Saxony (German: Sächsischer Landtag; Upper Sorbian: Sakski krajny sejm), also known in English as the Saxon State Parliament, is the legislature of the Free State of Saxony, one of Germany's sixteen states. It is responsible for legislation, control of the government, and electing some state officials. The Landtag has existed in various forms since 1831, but the current body was established during German reunification in 1990. The Landtag is directly elected and has a term of five years.
Muzaffarabad Cricket Stadium
The Muzaffarabad Cricket Stadium (a.k.a. Narol Cricket Stadium; Urdu: مظفر آباد کرکٹ اسٹیڈیم or MCS) is a cricket stadium in Muzaffarabad, Azad Kashmir. The stadium is situated near Azad Jammu Kashmir Medical College. It has hosted all the matches of the Kashmir Premier League so far.

Previously, the venue has been used as a hospital during earthquakes.

Muzaffarabad
Muzaffarabad is a city in Pakistani-administered Azad Kashmir in the disputed Kashmir region. It is the largest city and the capital of Azad Kashmir, which is a Pakistani-administered administrative territory.

The city is located in Muzaffarabad District, near the confluence of the Jhelum and Neelum rivers. The district is bounded by the Pakistani province of Khyber Pakhtunkhwa in the west, the Kupwara and Baramulla districts of Indian-administered Jammu and Kashmir in the east, and the Neelum District in the north.
Asadul Islam Sakib
Asadul Islam Sakib (Bengali: আসাদুল ইসলাম সাকিব; born 29 July 2005) is a Bangladeshi professional footballer who plays either as a full-back or winger for Bangladesh Premier League club Bangladesh Police FC.

Bangladesh Police FC
Bangladesh Police Football Club (also known as Bangladesh Police Athletic Club) is a professional football club based in Dhaka, Bangladesh. The club was founded by Bangladesh Police and formerly East Pakistan Police. They previously played in the First Division Football League in 1998 – then the second tier league. Police FC became champions of the Second Division in 2013–14. The club gained promotion to the Bangladesh Football League for the first time by becoming champions of the 2018-19 Bangladesh Championship League.
Wielki Buczek, Złotów County
Wielki Buczek (Polish pronunciation: [ˈvjɛlkʲi ˈbutʂɛk]) is a village in the administrative district of Gmina Lipka, within Złotów County, Greater Poland Voivodeship, in north-central Poland. It is situated in the ethnocultural region of Krajna in northern Greater Poland.

Krajna
Krajna is a forested historical region in the north of Greater Poland in Poland, situated in the border area between the Greater Poland, Kuyavian-Pomeranian and Pomeranian Voivodeships. The region consists of parts of Złotów, Piła, Sępólno, Nakło, Bydgoszcz and Człuchów counties, namely the urban gmina of Złotów, the rural gmina of Złotów and the urban-rural gminas of Krajenka, Wysoka, Wyrzysk, Łobżenica, Kamień Krajeński, Sępólno Krajeńskie, Więcbork, Nakło nad Notecią, Koronowo and Debzno.  The name of Krajna is derived from the Slavic word for borderland (between Greater Poland and Pomerania), cf. Krajina.

The main towns in the region are Złotów and Nakło nad Notecią. Since 1932, Krajna has own regional anthem, composed by Paweł "Krajnomir" Jasiek

Part of the region forms a protected area called Krajna Landscape Park.
Life Study (project)
Life Study  is a cross-disciplinary research study that will look at the health and wellbeing of thousands of children across the UK. It will collect a large amount of information on the health, growth and life factors of a new generation of children born in the UK.  
This study will create a large storehouse of social, medical and environmental information and linked routine health data for use by UK academics and policy communities. The information in this storehouse resource will help answer questions regarding early life development of health and disease, and physical, psychological and social well-being.

It is funded by the UK Department for Business, Innovation and Skills (BIS), Economic and Social Research Council (ESRC) and Medical Research Council (MRC) academics from the Institute of Child Health's Paediatric Epidemiology Unit at University College London (UCL) are leading the study, with Professor Carol Dezateux the Director of the project.

Economic and Social Research Council
The Economic and Social Research Council (ESRC) is a council of UK Research and Innovation (UKRI), a non-departmental public body sponsored by the Department for Science, Innovation and Technology, responsible for funding and support for research and training in the social sciences. It is the UK's largest organisation for funding research on economic and social issues.
Sweetwater Creek (Logan Creek tributary)
Sweetwater Creek is a stream in western Reynolds and northeastern Shannon counties of the Ozarks of southern Missouri. It is a tributary of the Logan Creek.

The stream headwaters are in Shannon County at 37°22′42″N 91°10′59″W﻿ / ﻿37.37833°N 91.18306°W﻿ / 37.37833; -91.18306 and the confluence with Logan Creek in Reynolds County is at 37°19′06″N 91°07′29″W﻿ / ﻿37.31833°N 91.12472°W﻿ / 37.31833; -91.12472.

According to historian Mayme Lucille Hamlett (citing W.A. Williams, then the Reynolds County superintendent of schools), Sweetwater Creek was so named on account of the hard water the stream contains, as "Hard water is often described as sweet water."

Hard water
Hard water is water that has a high mineral content (in contrast with "soft water"). Hard water is formed when water percolates through deposits of limestone, chalk or gypsum, which are largely made up of calcium and magnesium carbonates, bicarbonates and sulfates.

Drinking hard water may have moderate health benefits. It can pose critical problems in industrial settings, where water hardness is monitored to avoid costly breakdowns in boilers, cooling towers, and other equipment that handles water.

In domestic settings, hard water is often indicated by a lack of foam formation when soap is agitated in water, and by the formation of limescale in kettles and water heaters. Wherever water hardness is a concern, water softening is commonly used to reduce hard water's adverse effects.
Limnobacter
Limnobacter is a genus of Gram-negative, non-spore-forming, aerobic, oxidase- and catalase-positive, motile bacteria with a single polar flagellum, of the family Burkholderiaceae and class Betaproteobacteria. Limnobacter species have the ability to oxidize thiosulfate.

Thiosulfate
Thiosulfate (IUPAC-recommended spelling; sometimes thiosulphate in British English) is an oxyanion of sulfur with the chemical formula S2O2−3. Thiosulfate also refers to the compounds containing this anion, which are the salts of thiosulfuric acid, such as sodium thiosulfate (Na2S2O3) and ammonium thiosulfate ((NH4)2S2O3).  Thiosulfate salts occur naturally. Thiosulfate rapidly dechlorinates water, and is  used to halt bleaching in the paper-making industry. Thiosulfate salts are mainly used for dyeing in textiles, and bleaching of natural substances.
Keith Bishop (cricketer)
Keith Charles Bishop (born 11 March 1949) is a former English cricketer.  Bishop was a right-handed batsman who bowled right-arm medium pace.  He was born in Bury St Edmunds, Suffolk.

Bishop made his debut for Suffolk in a List A match debut against Buckinghamshire in the 1979 Gillette Cup.  In this match, he took the wicket of Keith Edwards for the cost of 27 runs from 12 overs, while with the bat he ended the Suffolk innings unbeaten on 0, with Suffolk winning the match by 2 wickets. He played a further List A match, which came in the 1980 Gillette Cup against Sussex. In this match, he scored 3 unbeaten runs, while he wasn't required to bat. He didn't feature in Minor counties cricket for Suffolk.

His son, Justin, played first-class cricket for Essex and Durham UCCE, as well as List A and Minor counties cricket for Suffolk.

1979 Gillette Cup
The 1979 Gillette Cup was the seventeenth Gillette Cup, an English limited overs county cricket tournament.  It was held between 27 June and 8 September 1979. The tournament was won by Somerset County Cricket Club who defeated Northamptonshire County Cricket Club by 45 runs in the final at Lord's.
Alice Sinclair
Alice Sinclair (born 17 November 1987) is an English fashion model best known for winning the reality TV program Make Me a Supermodel screened on Five.

Her "quirky personality" and odd looks saw her beat twelve other finalists to victory in the live catwalk finale, April 2005.

Sinclair decided to shake off all association with the program and prove herself in the fashion world. She enjoyed success, modelling across the world for magazines including Vogue Italia, Glamour, Marie Claire and Cosmopolitan, and appearing in print and TV ads for Levi's, H&M, Nokia, Fred Perry and Fabris Lane.

Annoyed by the negative stereotypes forced on models, she remarked, "There are millions of beautiful women out there and that isn't enough to succeed," and decided to leave modelling after two years to continue the studies she had put on hold.

She was educated in England at the all-girls' Henrietta Barnett School.

H&M
H & M Hennes & Mauritz AB, commonly known by its brand name H&M, is a Swedish multinational clothing company headquartered in Stockholm. Built on a fast fashion business model, the retailer sells apparel, accessories, and homeware. The company operates thousands of stores across 75 geographical markets and employs over 171,000 people worldwide.

H&M is the second-largest international clothing retailer after Inditex. H&M was founded by Erling Persson in 1947 under the name Hennes. The CEO of H&M from 2020 to 2024 was Helena Helmersson. The current CEO, as of January 2024, is Daniel Ervér.
2005 Southeastern Conference baseball tournament
The 2005 Southeastern Conference baseball tournament was held at Hoover Metropolitan Stadium in Hoover, Alabama from May 25 through 29.  Mississippi State won the tournament and earned the Southeastern Conference's automatic bid to the 2005 NCAA tournament.

Hoover, Alabama
Hoover is a city in Jefferson and Shelby counties in north central Alabama, United States. Hoover is the largest suburban city in Alabama and the sixth largest city in Alabama. The population was 92,606 at the 2020 census. Hoover is part of the Birmingham, AL Metropolitan Statistical Area and is also included in the Birmingham-Cullman-Talladega, AL Combined Statistical Area. Hoover's territory is along the foothills of the Appalachian Mountains.

The Birmingham Barons Minor League Baseball team, which traces its history to 1885, played its home games at the 10,800-seat Hoover Metropolitan Stadium from 1988 through 2013, when it moved to Regions Field in the Parkside District of Birmingham.
Ursa Louis Freed
Ursa Louis Freed (a.k.a. Ersa, 21 June 1890 – 5 July 1957) was an American architect active in North and South Dakota. A number of his works are listed on the U.S. National Register of Historic Places. He was a member of the American Institute of Architects from 1951 until his death in 1957.

Works by U.L. Freed include (with attribution):

Codington County Courthouse (built 1929), 1st Ave., SE, Watertown, South Dakota (Freed, Perkins & McWayne), NRHP-listed

Ipswich Baptist Church (built 1924), Main St. and 3rd Ave., Ipswich, South Dakota (Freed, U.L.), NRHP-listed

Municipal Building/City Hall (built 1941), 206 Main Street, Faith, South Dakota (Freed, U.L, Works Progress Administration), NRHP-listed

Immaculate Conception Catholic Church (built 1949), Winner, South Dakota

At least one building in the Aberdeen Historic District in Aberdeen, South Dakota.

Perkins & McWayne
Perkins & McWayne was an architectural firm based in Sioux Falls, South Dakota, and active throughout the state of South Dakota. It was established in 1917 by architects Robert A. Perkins and Albert McWayne.