hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Cytoskeletal drugs
Cytoskeletal drugs are small molecules that interact with the cytoskeletal proteins actin or tubulin. These drugs affect the cytoskeleton in one of three main ways: stabilizing cytoskeletal filaments, preventing the polymerization of protein monomers, or promoting the depolymerization of existing filaments.

Drugs that target microtubules, such as paclitaxel (taxol), are often used in chemotherapy for the treatment of cancer. In contrast, drugs that target actin have limited clinical use due to severe off-target effects but remain valuable tools in cellular research.

Demecolcine
Demecolcine (INN; also known as colcemid) is a drug used in chemotherapy. It is closely related to the natural alkaloid colchicine with the replacement of the acetyl group on the amino moiety with methyl, but it is less toxic. It depolymerises microtubules and limits microtubule formation (inactivates spindle fibre formation), thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed.

During cell division, demecolcine inhibits mitosis at metaphase by inhibiting spindle formation. Medically, demecolcine has been used to improve the results of cancer radiotherapy by synchronising tumour cells at metaphase, the radiosensitive stage of the cell cycle.

In animal cloning procedures, demecolcine makes an ovum eject its nucleus, creating space for insertion of a new nucleus.
2006 Sioux Falls Cougars football team
The 2006 Sioux Falls Cougars football team represented the University of Sioux Falls in the 2006 NAIA football season. The Cougars won the 2006 NAIA Football National Championship with a 23–19 victory over the top-ranked St. Francis Cougars. The team also won the Great Plains Athletic Conference championship with a perfect 10–0 record. This was the school's second NAIA Championship (1996). The team was coached by Kalen DeBoer.

1996 Sioux Falls Cougars football team
The 1996 Sioux Falls Cougars football team represented the University of Sioux Falls in the 1996 NAIA Division II football season. Led by head coach Bob Young in his 14th season, the Cougars won their first NAIA Division II Football National Championship with a 47–25 victory over the Western Washington Vikings. The team was also the South Dakota-Iowa Intercollegiate Conference champion.
1993 Southwest Conference men's basketball tournament
The 1993 Southwest Conference men's basketball tournament was held March 12–14, 1993, at Reunion Arena in Dallas, Texas.

Number 5 seed Texas Tech defeated 3 seed Houston 88-76 to win their 4th championship and receive the conference's automatic bid to the 1993 NCAA tournament.

1992–93 Houston Cougars men's basketball team
The 1992–93 Houston Cougars men's basketball team represented the University of Houston as a member of the Southwest Conference during the 1992–93 NCAA men's basketball season. The head coach was Pat Foster, and the team played its home games at the Hofheinz Pavilion in Houston, Texas.

After the season, Foster left to take the head coaching position at Nevada, and assistant Alvin Brooks was elevated to take his place.
Nokia C6-00
The Nokia C6-00 is a smartphone manufactured by Nokia, running the Symbian S60v5 operating system. It was announced on April 13, 2010. It is the fifth Symbian-based Nokia device featuring a slide-out QWERTY keyboard. It shares most of its hardware and software specifications as the N97 mini . One of the differences is that the sliding mechanism is flat, unlike the upward angle in the N97 and more similar to the Nokia E75. The phone has a 5-megapixel camera, though unlike the N97 mini, it lacked the Zeiss optics. It also has a secondary camera in front for video calls. The Nokia C6-01 is the successor to the C6-00 featuring the newer Symbian^3 operating system, but omitted the keyboard.

All applications for similar devices like the N97, the N97 Mini, the 5800 XpressMusic, and the 5230/5530 are compatible with the C6-00.

Nokia N97 Mini
The Nokia N97 Mini, announced in September 2009 and released two months later, is a refined and a slightly smaller version of the original Nokia N97. Nokia N97 Mini addressed many of its predecessor’s shortcomings and criticisms, was well reviewed and went on to win several industry awards for the best handset.
2019–20 Nemzeti Bajnokság I (women's handball)
The 2019–20 Nemzeti Bajnokság I (known as the K&H női kézilabda liga for sponsorship reasons) was the 69th season of the Nemzeti Bajnokság I, Hungarian premier Handball league. On 9 April 2020 the Hungarian Handball Federation decided to cancel the season with immediate effect due to the COVID-19 pandemic. In the meaning of the decision there will be no national champion named, the results of the season will be deleted and the final league table of the 2018/19 season will determine which clubs will participate in the international competitions in 2020/21.

Nemzeti Bajnokság I (women's handball)
The Nemzeti Bajnokság I (English: National Championship I, commonly abbreviated NB I) is the top professional league for Hungarian women's team handball clubs. It is administered by the Hungarian Handball Federation.
Matilda of Bavaria, Margravine of Meissen
Matilde of Bavaria (aft. 21 June 1313 – 2 July 1346) Meißen) was the eldest daughter of Louis IV, Holy Roman Emperor and his first wife Beatrix of Świdnica. Matilde was a member of the House of Wittelsbach.

House of Wittelsbach
The House of Wittelsbach (German: Haus Wittelsbach) is a former Bavarian dynasty, with branches that have ruled over territories including the Electorate of Bavaria, the Electoral Palatinate, the Electorate of Cologne, Holland, Zeeland, Sweden (with Swedish-ruled Finland), Denmark, Norway, Hungary, Bohemia, and Greece. Their ancestral lands of Bavaria and the Palatinate were prince-electorates, and the family had three of its members elected emperors and kings of the Holy Roman Empire. They ruled over the Kingdom of Bavaria which was created in 1805 and continued to exist until 1918.

The House of Windsor, the reigning royal house of the British monarchy, are descendants of Sophia of Hanover (1630–1714), a Wittelsbach Princess of the Palatinate by birth and Electress of Hanover by marriage, who had inherited the succession rights of the House of Stuart and passed them on to the House of Hanover.
Saparbek Safarov
Saparbek Dibirovich Safarov (Russian: Сапарбек Сафаров; born 14 October 1986) is a Russian mixed martial artist, who competes in the light heavyweight division. He competed for the Ultimate Fighting Championship.

Light heavyweight (MMA)
The light heavyweight division in mixed martial arts contains different weight classes.

The UFC's light heavyweight ranges from 186 to 205 lb (84 to 93 kg).

The ONE Championship's light heavyweight division (also known as cruiserweight) has an upper limit of 102.1 kg (225.1 lb).

The Road FC's light heavyweight division places the upper limit at 205 lb (93 kg).

The Misfits MMA's light heavyweight division uses the boxing light heavyweight format. (175 Ib limit).

Light heavyweight is a weight class in mixed martial arts, which generally refers to competitors weighing from 186 to 205 lb (84 to 93 kg). It sits between the lighter middleweight division, and the heavyweight division. The light heavyweight limit, as defined by the Nevada State Athletic Commission and the Association of Boxing Commissions is 206 lb (93 kg).
2019 Southern Conference softball tournament
The 2019 Southern Conference softball tournament was held at Frost Stadium on the campus of the University of Tennessee at Chattanooga in Chattanooga, Tennessee, from May 8 through May 11, 2019. Chattanooga won their fourteenth tournament championship and earned the SoCon's automatic bid to the 2019 NCAA Division I softball tournament.

2019 NCAA Division I softball tournament
The 2019 NCAA Division I softball tournament was held from May 31 to June 4, 2019, as the final part of the 2019 NCAA Division I softball season. Thirty-two teams were awarded automatic bids as champions of their conferences, and the remaining 32 were selected at-large by the NCAA Division I softball selection committee. The 64-team, double-elimination tournament concluded with the 2019 Women's College World Series at ASA Hall of Fame Stadium in Oklahoma City. The UCLA Bruins won their 13th championship, defeating the Oklahoma Sooners in two games.
Diversicon
Diversicon is an annual speculative fiction (science fiction and fantasy, or SF) convention held in July or August in the Minneapolis-Saint Paul, Minnesota area.  Diversicon provides programming and social opportunities to encourage the multicultural, multimedia exploration and celebration of SF by those within and outside of the traditional SF community. Diversicon includes both live and posthumous guests. It is sponsored by  SF Minnesota.

Otherwise Award
The Otherwise Award, originally known as the James Tiptree Jr. Award, is an American annual literary prize for works of science fiction or fantasy that expand or explore one's understanding of gender. It was initiated in February 1991 by science fiction authors Pat Murphy and Karen Joy Fowler, subsequent to a discussion at WisCon, a feminist SF conference.

In addition to the award itself, the judges publish an Honor List, which they describe as "a strong part of the award's identity", "used by many readers as a recommended reading list".

In 2024, the award administrators announced that they would be switching from a single winner each year to a shortlist of three to six winners.

The award was originally named for Alice B. Sheldon, who wrote under the pseudonym James Tiptree Jr. Due to controversy over the appropriateness of naming an award after Tiptree, the committee administering the award announced on October 13, 2019, that the award would be renamed the Otherwise Award.
Flagon
A flagon (/ˈflæɡən/) is a large leather, metal, glass, plastic or ceramic vessel, used for storing and pouring drink, whether this be water, ale, or another liquid. They are generally not intended to be drunk from directly, like a cup or tankard. A flagon is typically of about 2 imperial pints (1.1 L) in volume, and it has either a handle (when strictly it is a jug), or (more usually) one or two rings at the neck. Sometimes the neck has a large flange at the top rather than rings.  The neck itself may or may not be formed into one, two or three spouts. The name comes from the same origin as the word "flask".

Tankard
A tankard is a form of drinkware consisting of a large, roughly cylindrical, drinking cup with a single handle. In recent centuries tankards were typically made of silver or pewter, but they can be made of other materials, for example glass, wood, pottery, or boiled leather. A tankard may have a hinged lid, and tankards featuring glass bottoms are also fairly common. Beer steins are a similar shape and use.
2023 Shamrock Rovers F.C. season
The 2023 Shamrock Rovers F.C. season started on 4 February when Shamrock Rovers defeated University College Dublin in the  Leinster Senior Cup. Shamrock Rovers were knocked–out of the UEFA Champions League on 18 July in the first qualifying round, knocked–out of the FAI Cup on 23 July in the first round, and knocked–out of the UEFA Europa Conference League on 3 August in the second qualifying round. Shamrock Rovers had won the previous three Premier Division championships coming into the 2023 season (2020, 2021, and 2022).

University College Dublin A.F.C.
University College Dublin Association Football Club, known commonly as UCD, is the football team of University College Dublin. They play in the League of Ireland First Division. Founded in 1895, the club was elected to the League of Ireland in 1979 under the management of Dr. Tony O'Neill. Since the 2008 season they have played at the UCD Bowl, also home to the college's rugby team. 'The Students' play in bright sky blue and navy. Their reserve and freshers teams play in the Leinster Senior League. The current manager is Donegal native William O'Connor.
Battle of Lena
The Battle of Lena occurred on 31 January 1208 and probably took place near Kungslena, in the Tidaholm Municipality in Västergötland, Sweden. It was an important battle between the Danish-backed King Sverker II of Sweden and Prince Eric. Eric's forces won a crushing victory; however, in July 1210, Sverker returned with a second army and was killed in the Battle of Gestilren.

Tidaholm Municipality
Tidaholm Municipality (Swedish: Tidaholms kommun) is a municipality in Västra Götaland County in western Sweden. Its seat is located in the city of Tidaholm.

The municipality is located on the banks of the river Tidan.

In the early 1970s a nationwide local government reform was carried out in Sweden. Urban and rural areas were merged into larger unitary municipalities. The former City of Tidaholm (instituted in 1910) was in 1974 amalgamated with the surrounding rural municipality Hökensås and parts of Dimbo and Fröjered. The number of original entities (as of 1863) within the present municipality is 20.

Many well-preserved medieval churches stand in the municipality. Some church sites also contain examples of early Scandinavian runestones.
2011 Premiership Rugby Sevens Series
The 2011 Premiership Rugby Sevens Series, named for sponsorship reasons as the 2011 J.P Morgan Asset Management Premiership Rugby 7s Series, was the second Rugby Union 7-a-side competition for the 12 2011-12 Aviva Premiership Clubs. It began on Friday 15 July and lasted four weeks, with the final at the Twickenham Stoop on 5 August 2011. Newcastle Falcons won the title, beating Saracens in the final.

Premiership Rugby Sevens Series
The Premiership Rugby Sevens Series was a friendly Rugby Sevens competition for the twelve Premiership Rugby clubs that will play the following season (i.e. the 2010 competition features the teams playing in the Aviva Premiership in the 2010–11 season). It was started in 2010, as an off-season competition, held during the months of July and August. Between 2014 and 2016 the competition included the four Welsh regions which compete in the Pro14.
Ranseren
Ranseren (Norwegian), also known as Bije-Ransarn (Swedish) or Bijjie Raentsere (Southern Sami), is a lake on the border between Norway and Sweden. The Norwegian side lies in Hattfjelldal Municipality in Nordland county (and it is inside Børgefjell National Park). The Swedish side of the lake is called Bije-Ransaren, which means "the upper Ransaren" and this part lies in Vilhelmina Municipality in Västerbotten County.

The brook that flows from the lake on the east side is called Saxån. It leads to the larger lake, Ransarn, which is located in Vilhelmina Municipality in Sweden. Bije-Ransaren is called the upper Ransarn in contrast to the bigger lake, which is referred to as "lower" Ransarn.

The lake lies about 10 kilometres (6.2 mi) from the village of Stekenjokk in Vilhelmina, Sweden. South of the Swedish side of the lake, about 0.5 kilometres (0.31 mi) from the border, is a small Sami house that was used during reindeer marking season.

Børgefjell National Park
Børgefjell National Park (Norwegian: Børgefjell nasjonalpark, Southern Sami: Byrkije vaarjelimmiedajve) is an undeveloped national park in Norway, straddling the border between Trøndelag and Nordland counties, along the border with Sweden. The park is undeveloped with few trails or other facilities for visitors. Visitors can hike for extended periods without seeing another person. The 1,447-square-kilometre (559 sq mi) park was originally established in 1963, and it was enlarged in 1973 and 2003. It now includes land in the municipalities of Hattfjelldal, Grane, Namsskogan, and Røyrvik.
Big Brother (Croatian TV series) season 4
Big Brother 4 is the fourth season of the Croatian reality television series Big Brother that began on 7 September 2007 and ended on 21 December 2007.

The maximum prize was 1.5 million HRK (200 000 EUR).  Every successful weekly task increased the final prize by the same amount.  Producers introduced penalties as a response to criticism of the second season, when they were perceived to be too tolerant of contestants' misbehavior. At the end of the show the prize was 1,005,000 HRK.  Vedran was the winner of the show.
In the fourth season 14 housemates entered the house.

Croatian kuna
The kuna (Croatian pronunciation: [kǔːna]; sign: kn; code: HRK) was the currency of Croatia from 1994 until 2023, when it was replaced by the euro. The kuna was subdivided into 100 lipa. It was issued by the Croatian National Bank and the coins were minted by the Croatian Mint.

In the Croatian language, the word kuna means 'marten' and lipa means 'linden tree', both references to their historical use in medieval trading.
Hydroxylation of estradiol
The hydroxylation of estradiol is one of the major routes of metabolism of the estrogen steroid hormone estradiol. It is hydroxylated into the catechol estrogens 2-hydroxyestradiol and 4-hydroxyestradiol and into estriol (16α-hydroxyestradiol), reactions which are catalyzed by cytochrome P450 enzymes predominantly in the liver, but also in various other tissues.

Estriol
Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estrone. Levels of estriol in women who are not pregnant are almost undetectable. However, during pregnancy, estriol is synthesized in very high quantities by the placenta and is the most produced estrogen in the body by far, although circulating levels of estriol are similar to those of other estrogens due to a relatively high rate of metabolism and excretion. Relative to estradiol, both estriol and estrone have far weaker activity as estrogens.

In addition to its role as a natural hormone, estriol is used as a medication, for instance in menopausal hormone therapy; for information on estriol as a medication, see the estriol (medication) article.
Lyulin Peak
Lyulin Peak (Bulgarian: връх Люлин, romanized: vrah Lyulin, IPA: [ˈvrɤx ʎoˈlin]) is a sharp double peak forming the east extremity of Delchev Ridge and Tangra Mountains, eastern Livingston Island in the South Shetland Islands, Antarctica.  The peaks rise to approximately 200 m, have rocky, ice-free slopes and surmount Renier Point.  The peaks are named after Lyulin Mountain in Bulgaria.

Delchev Ridge
Delchev Ridge (Delchev Hrebet \'del-chev 'hre-bet\) is the eastern ridge of the Tangra Mountains, Livingston Island extending 10 km east-northeastward from Devin Saddle to Renier Point.  The ridge is named in association with its summit Delchev Peak (ca. 940 m).

The north slopes of the ridge between Elena Peak and Renier Point together with the adjacent portion of Sopot Ice Piedmont are a popular site for backcountry skiing and climbing, with skiers landed by Zodiac rigid inflatable boats from cruise ships visiting the Half Moon Island area.
Yin Lili
Yin Lili (born 11 November 1979) is a female Chinese middle-distance runner.

On 18 October 1997 in Shanghai she ran the 1500 metres in 3:53.91 minutes. This ranks her sixth in the world of all time, behind Qu Yunxia, Jiang Bo, Lang Yinglai, Wang Junxia and Tatyana Kazankina.

At the 1998 World Junior Championships she won both the 3000 and the 5000 metres.

Yin never had a distinguished career after this, rarely competing internationally. In 2001, she received a two-year suspension for doping.

Lang Yinglai
Lang Yinglai (born 22 August 1979) is a female Chinese former middle-distance runner.

On 18 October 1997 at the 1997 National Games of China in Shanghai she ran the 1500 metres in 3:51.34 minutes, taking the silver medal behind Jiang Bo. This time ranks her as the fourth fastest in the world of all time, only behind Genzebe Dibaba, Qu Yunxia and Jiang. This is also the world record for junior athletes. Four days later she won the 800 metres title at the National Games in 1:57.62. She took an 800 m and 1500 m double at the 1997 Asian Junior Athletics Championships.

Lang never had a distinguished career after this, rarely competing internationally.
San Jose Spiders (NWBL)
The San Jose Spiders were a women's professional basketball team in the National Women's Basketball League (NWBL).  Based in San Jose, California, they played from 2005 to 2006. In 2005, the Spiders went 5–19. In 2006, San Jose improved to a 8–10 in the regular season under new head coach Fred Chmiel. They lost to Colorado in the semi-final and defeated San Francisco in the third place game, making their record 9–11. Notable players included Brittany Jackson, Julie McBride, Lindsey Yamasaki, and Natalie Nakase.

San Francisco Legacy
The San Francisco Legacy were the last original franchise of the National Women's Basketball League (NWBL). Originally established in 2001 as the Kansas City Legacy, the franchise moved in 2003 to Knoxville, Tennessee, and became the Tennessee Fury.  Then in 2004 it moved to Dallas, and was known as the Dallas Fury, where it won the league championship that year.  The team moved to Oakland and took its original name in 2006.
Russula maculata
Russula maculata is a species of mushroom in the genus Russula. Its cap ranges from 4–10 centimetres (1+1⁄2–4 in) wide, with hues varying from whitish to red. It is difficult to distinguish reliably and its edibility is unknown.

Russula
Russula is a very large genus composed of around 750 worldwide species of fungi. The genus was described by Christian Hendrik Persoon in 1796.

The mushrooms are fairly large, and brightly colored – making them one of the most recognizable genera among mycologists and mushroom collectors. Their distinguishing characteristics include usually brightly coloured caps, a white to dark yellow spore print, brittle, attached gills, an absence of latex, and absence of partial veil or volva tissue on the stem. Microscopically, the genus is characterised by the amyloid ornamented spores and flesh (trama) composed of spherocysts. Members of the related genus Lactarius have similar characteristics but emit a milky latex when their gills are broken.

The ectomycorrhizal mushrooms are typically common. Although some species are toxic, a number of others are edible.
2024 Cronulla-Sutherland Sharks season
The 2024 Cronulla-Sutherland Sharks season is the 58th season in the club's history and they compete in the National Rugby League.

The club is coached by Craig Fitzgibbon in his third season with the Sharks and captained by Dale Finucane and Cameron McInnes. On Tuesday 23 April, in the lead up to Round 8, co-captain Dale Finucane announced his immediate retirement from the NRL on medical advice, due to repeated head knocks.

Dale Finucane
Dale Finucane (born 7 September 1991) is a former Australian professional rugby league footballer who played as a lock forward for the Cronulla-Sutherland Sharks in the National Rugby League (NRL). Finucane is a dual premiership winner 2017 and 2020 with the Melbourne Storm.

Finucane previously played for the Canterbury-Bankstown Bulldogs and Melbourne Storm in the NRL. He has played for the Country Origin and New South Wales sides.
1888 Dublin Senior Hurling Championship
The 1888 Dublin Senior Hurling Championship was the second staging of the Dublin Senior Hurling Championship since its establishment by the Dublin County Board.

Metropolitans entered the championship as the defending chammpions.

The final was played on 27 May 1888 at Clonturk Park in Dublin, between Kickhams and Dunleary, in what was their first ever meeting in the final. Kickhams won the match by 2–06 to 1–02 to claim their first ever championship title.

1887 Dublin Senior Hurling Championship
The 1887 Dublin Senior Hurling Championship was the inaugural staging of the Dublin Senior Hurling Championship since its establishment by the Dublin County Board.

The final was played on 17 April 1887 at Elm Park in Dublin, between Metropolitans and Davitts, in what was their first ever meeting in the final. Metropolitans won the match by 4–12 to 1–05 to claim their first ever championship title.