hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Linustedastat
Linustedastat (developmental code names FOR-6219 and OG-6219) is a 17β-hydroxysteroid dehydrogenase 1 (17β-HSD1; HSD17B1) inhibitor which is under development for the treatment of endometriosis. It is a steroidal compound derived from estrone and works by preventing the formation of the more potent estrogen estradiol from the minimally active precursor estrone. This in turn results in antiestrogenic effects that may be useful in the treatment of estrogen-dependent conditions. As of November 2023, the drug is in phase 2 clinical trials for endometriosis. It is also under preclinical investigation for treatment of breast cancer and endometrial cancer.

Estrone
Estrone (E1), also spelled oestrone, is a steroid, a weak estrogen, and a minor female sex hormone. It is one of three major endogenous estrogens, the others being estradiol and estriol. Estrone, as well as the other estrogens, are synthesized from cholesterol and secreted mainly from the gonads, though they can also be formed from adrenal androgens in adipose tissue. Relative to estradiol, both estrone and estriol have far weaker activity as estrogens. Estrone can be converted into estradiol, and serves mainly as a precursor or metabolic intermediate of estradiol. It is both a precursor and metabolite of estradiol.

In addition to its role as a natural hormone, estrone has been used as a medication, for instance in menopausal hormone therapy; for information on estrone as a medication, see the estrone (medication) article.
2017 Dutch National Track Championships
The 2017 Dutch National Track Championships were the Dutch national Championship for track cycling, organized by the KNWU. They took place in Alkmaar, the Netherlands on 20, 27, 28 and 29 December 2017

Dutch National Track Championships
The Dutch National Track Championships are the set of Dutch national championship events for the various disciplines and distances in track cycling. They are organized by the KNWU. There are competitions of various track cycling disciplines in age, gender and disability categories. Women's events are shorter than men's. Championships are open to all licensed riders.

The winner of a national championship discipline receives a gold medal and a national jersey. Silver and bronze medals are awarded to the second and third place contestants. National champions wear their national jersey until the following year's championship, but they may wear it only in the type of event in which they won it. Former champions can wear rainbow cuffs to their everyday jerseys.
Fidan Aliti
Fidan Aliti (born 3 October 1993) is a professional footballer who plays as a centre-back for Süper Lig club Alanyaspor. Born in Switzerland, he originally represented Albania at international level before switching in 2017 to represent Kosovo.

2017–18 Albanian Cup
2017–18 Albanian Cup (Albanian: Kupa e Shqipërisë) was the sixty-sixth season of Albania's annual cup competition. Tirana are the defending champions. Skënderbeu won the title for the first time in their history.

Ties are played in a two-legged format similar to those of European competitions. If the aggregate score is tied after both games, the team with the higher number of away goals advances. If the number of away goals is equal in both games, the match is decided by extra time and a penalty shoot-out, if necessary.
Royal Vietnamese army
The Royal Vietnamese army was the primary military body of the Vietnamese states of Jinghai and Đại Việt and the armed forces of the Vietnamese monarchy from 938 to 1789. It was disbanded and succeeded by the Imperial Vietnamese army of the Nguyễn dynasty in early 19th century.

Sabre
A sabre or (American English) saber (/ˈseɪbər/ SAY-bər) is a type of backsword with a curved blade associated with the light cavalry of the early modern and Napoleonic periods. Originally associated with Central European cavalry such as the hussars, the sabre became widespread in Western Europe during the Thirty Years' War. Lighter sabres also became popular with infantry of the early 17th century. In the 19th century, models with less curving blades became common and were also used by heavy cavalry.

The military sabre was used as a duelling weapon in academic fencing in the 19th century, giving rise to a discipline of modern sabre fencing (introduced in the 1896 Summer Olympics) loosely based on the characteristics of the historical weapon.
The Groke
The Groke (Swedish: Mårran, Finnish: Mörkö) is a fictional character in the Moomin stories created by Swedish-speaking Finnish author Tove Jansson.

The Groke is a melancholic and lonely character. She appears as a big dark sheet ghost with a big nose, who passively freezes everything around her.

Sniff (Moomin character)
Sniff (Swedish: Sniff) is a character in the Moomin stories created by Swedish-speaking Finnish writer Tove Jansson. His debut is in the first Moomin-book The Moomins and the Great Flood. In addition to books, he is also a prominent character in the Moomin comics and animations.
Murder of Peter R. de Vries
On the evening of 6 July 2021, Dutch investigative journalist and crime reporter Peter R. de Vries was shot in the head after leaving the television studio of RTL Boulevard in Amsterdam, where he had appeared as a guest. Several shots were fired at him in the Lange Leidsedwarsstraat, near the Leidseplein, while he was walking to his car. De Vries was taken to the VU University Medical Center in critical condition. He died of his injuries on 15 July.

Ferdinand Grapperhaus
Ferdinand Bernhard Joseph "Ferd" Grapperhaus (born 8 November 1959) is a Dutch politician who served as Minister of Justice and Security in the Third Rutte cabinet from 26 October 2017 until 10 January 2022. He is a member of the Christian Democratic Appeal (CDA).
Na Khun Yai
Na Khun Yai (Thai: นาคูณใหญ่, pronounced [nāː kʰūːn jàj]) is a subdistrict (tambon) in Nakhon Phanom Province, administered by Na Wa District in northeastern Thailand (Isan).

The village is about 900 km north of Bangkok. Na Khun Yai is underdeveloped, with agriculture as the main economic activity.

Nakhon Phanom province
Nakhon Phanom province (Thai: นครพนม, pronounced [ná(ʔ).kʰɔ̄ːn pʰā.nōm], lit. 'Mountain City'; Northeastern Thai: นครพนม, pronounced [nà(ʔ).kʰɔ᷇ːn pʰā.no᷇m]) is one of Thailand's seventy-six provinces (changwat) lies in upper northeastern Thailand also called Isan. Directly adjacent provinces are (from south clockwise): Mukdahan, Sakon Nakhon, and Bueng Kan. To the northeast it borders Khammouan of Laos.
Caritas Australia
Caritas Australia is an Australian Catholic agency for development cooperation and humanitarian aid.

Caritas is a member of Caritas Internationalis and its region Caritas Oceania, as well as of the Australian Council for International Development (ACFID).

Caritas Oceania
Caritas Oceania is an Oceanian confederation of Catholic social, humanitarian, and relief organisations. It is one of the seven regional confederations of Caritas Internationalis members. Caritas Oceania consists of seven member organisations from across the Pacific Islands, Australia and New Zealand.
2020 Milano–Torino
The 2020 Milano–Torino was the 101st edition of the Milano–Torino cycling classic. It was held on 5 August 2020 and was rated as a 1.Pro event on the 2020 UCI Europe Tour and 2020 UCI ProSeries. Unlike previous editions of the race, which were more suited for climbers and puncheurs, this year's edition was mostly flat and favored the sprinters. The race, which started in Mesero and finished in Stupinigi, was won by French rider Arnaud Démare of Groupama–FDJ.

2020 UCI Europe Tour
The 2020 UCI Europe Tour was the sixteenth season of the UCI Europe Tour. The 2020 season began on 25 January 2020 with the GP Belek and ended on 14 October 2020 with the Scheldeprijs.

Throughout the season, points are awarded to the top finishers of stages within stage races and the final general classification standings of each of the stages races and one-day events. The quality and complexity of a race also determines how many points are awarded to the top finishers, the higher the UCI rating of a race, the more points are awarded.

The UCI ratings from highest to lowest are as follows:

Multi-day events: 2.Pro, 2.1 and 2.2

One-day events: 1.Pro, 1.1 and 1.2
District of Columbia Court of Appeals
The District of Columbia Court of Appeals is the highest court of the District of Columbia, in the United States. The court was established in 1942 as the Municipal Court of Appeals, and it has been the court of last resort for matters of D.C. local law since 1970. It and the Superior Court of the District of Columbia compose the District of Columbia's court system. It is located in the former District of Columbia City Hall building at Judiciary Square.

The D.C. Court of Appeals is the equivalent of a state supreme court. Because the District of Columbia is not a U.S. state, however, the court's authority derives from the U.S. Congress rather than from the inherent sovereignty of the states. The D.C. Court of Appeals is sometimes confused with the U.S. Court of Appeals for the District of Columbia Circuit, which is the federal U.S. court of appeals that covers the District of Columbia.

State supreme court
In the United States, a state supreme court (known by other names in some states) is the highest court in the state judiciary of a U.S. state. On matters of state law, the judgment of a state supreme court is considered final and binding in both state and federal courts.

Generally, a state supreme court, like most appellate tribunals, is exclusively for hearing appeals of legal issues. Although state supreme court rulings on matters of state law are final, rulings on matters of federal law (generally made under the state court's concurrent jurisdiction) can be appealed to the Supreme Court of the United States. Each state supreme court consists of a panel of judges selected by methods outlined in the state constitution. Among the most common methods for selection are gubernatorial appointment, non-partisan election, and partisan election, but the different states follow a variety of procedures.
Rajiv Gandhi School of Intellectual Property Law
Rajiv Gandhi School of Intellectual Property Law, IIT Kharagpur (RGSOIPL or IIT Kgp Law School) is a law school located in Kharagpur, West Bengal, India. An academic unit of Indian Institute of Technology Kharagpur, it is the first law school to be established in an Indian Institute of Technology (IIT). It was set up in collaboration with the George Washington University Law School, Washington DC and is the only law school within the IIT system. It is also the first law school in India imparting full-time Intellectual Property education along with other regular courses prescribed by the Bar Council of India. School maintain a Legal Aid and IP Facilitation Cell to provide legal services to the needy peoples, faculty and students of the school associated with the cell provide legal aid as an enabling and outreach activity.

Law school
A law school (also known as a law centre/center, college of law, or faculty of law) is an institution, professional school, or department of a college or university specializing in legal education, usually involved as part of a process for becoming a judge, lawyer, or other legal professional within a given jurisdiction. Depending on the country, legal system, or desired qualifications, the coursework is undertaken at undergraduate, graduate, or both levels.
Athletics in Jamaica
Since the early 20th century, Jamaica has won 65 Commonwealth Golds, 40 World Championship Golds and 27 Olympic gold medals in athletics alone. Jamaica has a population of 2.85 million people, making it the 138th most populous country in the world.

Veronica Campbell Brown
Veronica Campbell Brown CD (née Campbell; born 15 May 1982) is a Jamaican retired track and field sprinter, who specialized in the 100 and 200 meters. An eight-time Olympic medalist, she is the second of three women in history to win two consecutive Olympic 200 m gold medals, after Bärbel Wöckel of Germany and compatriot Elaine Thompson-Herah. Campbell-Brown is one of only eleven athletes to win World Championship titles at the youth, junior, and senior levels of an athletic event.

She holds personal bests of 10.76 seconds for the 100 m and 21.74 seconds for the 200 m. She was the 100 m gold medallist at the 2007 World Championships in Athletics and the 200 m gold medallist at the 2011 World Championships in Athletics. She has also won seven silver medals and one bronze medal in her career at the World Championships in Athletics. Over 60 metres, she is a two-time champion at the IAAF World Indoor Championships.
Bondhusbrea
Bondhusbrea is a glacier in Kvinnherad Municipality in Vestland county, Norway. The glacier is an offshoot of the vast Folgefonna glacier, and it lies inside the Folgefonna National Park.  The glacier has a length of around 4 kilometres (2.5 mi) and a height difference of about 1,100 metres (3,600 ft) from its highest to its lowest points.

The glacier is located at the end of the small Bondhusdalen valley, just south of the village of Sunndal on the shore of the Maurangsfjorden. Water draining under the glacier is caught through a tunnel and exploited in the Mauranger Hydroelectric Power Station.

Maurangerfjorden
Maurangerfjorden is a fjord in Kvinnherad Municipality in Vestland county, Norway.  The 12-kilometre (7.5 mi) long fjord is a small branch off of the main Hardangerfjorden. The inner end of the Maurangsfjorden branches into the Nordrepollen and Austrepollen. There are several villages located along the fjord: Ænes, Sunndal, Austrepollen, Nordrepollen, and Gjetingsdalen. The Mauranger Hydroelectric Power Station is located in the village of Austrepollen.
Judiciary of Macau
The Judiciary of Macau is responsible for the administration of justice in Macau. It hears all prosecutions and civil disputes, including disputes between individuals and the government. It is fundamental to Macau's legal system that members of the judiciary are independent of the executive and legislative branches of the government. The courts of law in Macau comprise the Court of Final Appeal  and 11 other courts. The President of the Court of Final Appeal of the Macau Special Administrative Region is head of the judiciary. A bilingual court system in which Chinese, Portuguese or both can be used was put in place, in accordance with the requirement of the Basic Law.

Government of Macau
The Government of the Macao Special Administrative Region, commonly known as the Macao Government, is the executive authorities of Macau. Formed on 20 December 1999 in accordance with the Sino-Portuguese Joint Declaration, it is headed by secretariats or commissioners and report directly to the chief executive. The affairs of the government are decided by secretaries, who are appointed by the chief executive and endorsed by the State Council of the Central People's Government in Beijing. As a special administrative region of China, Macau has a high degree of autonomy, in light of the "One Country, Two Systems" policy. The Macau Government, financially independent from the Central People's Government, oversees the affairs of Macau.
Earth's crustal evolution
Earth's crustal evolution involves the formation, destruction and renewal of the rocky outer shell at that planet's surface.

The variation in composition within the Earth's crust is much greater than that of other terrestrial planets. Mars, Venus, Mercury and other planetary bodies have relatively quasi-uniform crusts unlike that of the Earth which contains both oceanic and continental plates. This unique property reflects the complex series of crustal processes that have taken place throughout the planet's history, including the ongoing process of plate tectonics.

The proposed mechanisms regarding Earth's crustal evolution take a theory-orientated approach. Fragmentary geologic evidence and observations provide the basis for hypothetical solutions to problems relating to the early Earth system. Therefore, a combination of these theories creates both a framework of current understanding and also a platform for future study.

Earth's crust
Earth's crust is its thick outer shell of rock, comprising less than one percent of the planet's radius and volume. It is the top component of the lithosphere, a solidified division of Earth's layers that includes the crust and the upper part of the mantle. The lithosphere is broken into tectonic plates whose motion allows heat to escape the interior of Earth into space.

The crust lies on top of the mantle, a configuration that is stable because the upper mantle is made of peridotite and is therefore significantly denser than the crust. The boundary between the crust and mantle is conventionally placed at the Mohorovičić discontinuity, a boundary defined by a contrast in seismic velocity.

The temperature of the crust increases with depth, reaching values typically in the range from about 700 to 1,600 °C (1,292 to 2,912 °F) at the boundary with the underlying mantle. The temperature increases by as much as 30 °C (54 °F) for every kilometer locally in the upper part of the crust.
Judo at the 1980 Summer Olympics – Men's 95 kg
Men's 95 kg competition in Judo at the 1980 Summer Olympics in Moscow, Soviet Union was held at Palace of Sports of the Central Lenin Stadium. The gold medal was won by Robert Van de Walle from Belgium.

Judo at the 1980 Summer Olympics
The Judo competition at the 1980 Summer Olympics was the first time that the medal count was not dominated by Japan, since the country joined the boycott of the games because of the 1979 Soviet invasion of Afghanistan. Medals were awarded to male judoka in eight competitions, seven weight classes and the open competition — two more than in 1976. All events were held at the Palace of Sports of the Central Lenin Stadium at Luzhniki (south western part of Moscow). The schedule started on July 27 and ended on August 2.
Spörer's law
In solar physics, Spörer's law is an empirical law for the variation of heliographic latitudes at which solar active regions form during a solar cycle. It was discovered by the English astronomer Richard Christopher Carrington around 1861. Carrington's work was refined by the German astronomer Gustav Spörer.

At the start of a solar cycle, active regions tend to appear around 30° to 45° latitude on the Sun's surface. As the cycle progresses, they appear at lower and lower latitudes, until they average 15° at solar maximum. The average latitude then continues to drift lower, down to about 7° and then while the old sunspot cycle fades, active regions of the new cycle start appearing at high latitudes.

Active region
In solar physics, an active region is a temporary feature in the Sun's atmosphere characterized by a strong and complex magnetic field. 
Active regions are often associated with sunspots and are commonly the source of violent eruptions such as coronal mass ejections and solar flares. The number and location of active regions on the solar disk at any given time is dependent on the solar cycle.
Alan Sampson
Alan Sampson is a British record producer, songwriter and musician. He has written and produced many songs with Jay Sean, including "Ride It," "Maybe," "Do You," "Far Away" (featuring Keisha Buchanan), and "Stay". He also co-wrote and co-produced "She" and "Drunk" on Zayn's debut studio album, Mind of Mine. Alan is currently signed to BMG UK.

Sampson has also produced music for Alesha Dixon, Parade, Craig David, Idris Elba, and Chasing Abbey.

Craig David
Craig Ashley David MBE (born 5 May 1981) is an English singer. He rose to fame in 1999, featuring on the single "Re-Rewind" by Artful Dodger. David's debut studio album, Born to Do It, was released in 2000, to great commercial success. He followed it up with eight more studio albums: Slicker Than Your Average (2002), The Story Goes... (2005), Trust Me (2007), Signed Sealed Delivered (2010), Following My Intuition (2016), The Time Is Now (2018), 22 (2022), and Commitment (2025). Over his career, David has collaborated with a diverse array of artists, including Sting, Tinchy Stryder, Big Narstie, Tiwa Savage and JoJo.
2015 WRC3 Championship
The 2015 FIA WRC3 Championship is the third season of WRC3, a rallying championship organised and governed by the Fédération Internationale de l'Automobile, running in support of the World Rally Championship. It was created when the Group R class of rally car was introduced in 2013. The Championship is composed by thirteen Rallies, and Drivers and Teams must nominate a maximum of six event. The best five results will be counted towards the championship.

Stéphane Lefebvre is the defending champion, as he won the 2014 title.

Rallye de France Alsace
The Rallye de France Alsace was a rally competition held in the Alsace region of France. The rally took place on roads in the Vosges mountains, as well as on similar vineyard tracks to Rallye Deutschland.

In 2010, it became the French round of the World Rally Championship, the Rallye de France, replacing the Tour de Corse rally in Corsica. After 5 editions, it was revealed in a meeting in January 2015 in Paris that the rally would no longer be part of the World Rally Championship due to local authorities in the Alsace region withdrawing support. The French round of the World Rally Championship returned to Tour de Corse in 2015.
IndusInd Securities
IndusInd Securities Limited formerly Reliance Securities Limited is a broking arm of Reliance Capital. It is one of India’s largest retail broking houses with over 1 million customers and a pan-India presence at more than 1,700 locations. The company is a corporate member of both the Bombay Stock Exchange (BSE) and the National Stock Exchange (NSE), and provides access to equities, derivatives, IPO's, mutual funds, bonds and corporate FDs.

National Stock Exchange of India
National Stock Exchange of India Limited, also known as the National Stock Exchange (NSE), is an Indian stock exchange based in Mumbai.  It is the 5th largest stock exchange in the world by total market capitalization, exceeding $5 trillion in May 2024.

NSE is under the ownership of various financial institutions such as banks and insurance companies. As of 2024, it is the world's largest derivatives exchange by number of contracts traded and the third largest in cash equities by number of trades for the calendar year 2023.
Rudby Hall
Rudby Hall, Skutterskelfe, North Yorkshire is a 17,377 sq ft (1,614.4 m2) country house dating from 1838. Its origins are older but the present building was built for the 10th Viscount Falkland and his wife by the architect Anthony Salvin. The house is Grade II* listed.

Jill Allibone
Jill Spencer Allibone (26 April 1932 – 3 February 1998) was an English architectural historian and the founder of the Mausolea and Monuments Trust. She wrote studies of Anthony Salvin and George Devey, and was a justice of the peace for over 20 years.
CSM Vulcan
Clubul Sportiv Municipal Mihai Viteazu Vulcan, commonly known as CSM Vulcan, or unofficially as Minerul Vulcan, is a Romanian football club based in Vulcan, Hunedoara County. Founded in 1921 as CS Vulcan and re-founded in 2016 as CSM Mihai Viteazu Vulcan, the club currently playing in the Liga IV – Hunedoara County.

1976–77 County Championship
The 1976–77 County Championship was the 35th season of the Liga IV, the fourth tier of the Romanian football league system. The champions of each county association play against one from a neighboring county in a play-off  to gain promotion to Divizia C.