hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
SPT-320
SPT-320, also formerly known as LYT-320, is a prodrug of agomelatine which is under development for the treatment of mood and anxiety disorders, for instance generalized anxiety disorder.

As an agomelatine prodrug, it acts as a melatonin receptor agonist and as a serotonin 5-HT2B and 5-HT2C receptor antagonist. The drug is taken by mouth and is said to bypass first-pass hepatic metabolism.

As of December 2023, SPT-320 is in the preclinical research phase of development. It is under development by Seaport Therapeutics and is being developed towards approval in the United States. The chemical structure of SPT-320 does not yet appear to have been disclosed.

Prodrug
A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. Instead of administering a drug directly, a corresponding prodrug can be used to improve how the drug is absorbed, distributed, metabolized, and excreted (ADME).

Prodrugs are often designed to improve bioavailability when a drug itself is poorly absorbed from the gastrointestinal tract. A prodrug may be used to improve how selectively the drug interacts with cells or processes that are not its intended target.  This reduces adverse or unintended effects of a drug, especially important in treatments like chemotherapy, which can have severe unintended and undesirable side effects.
Local Government Leaders' Council
The Local Government Leaders' Council or simply the Leaders' Council is a forum in the United Kingdom that brings together the Secretary of State for Housing, Communities and Local Government, other ministers in the UK government, and leaders of representative bodies of local government.

Local government in the United Kingdom
Local government in the United Kingdom has origins which pre-date the United Kingdom itself, as each of the four countries of the United Kingdom has its own separate system. For an overview, see Administrative geography of the United Kingdom. For details, see:

Local government in England

Local government in Northern Ireland

Local government in Scotland

Local government in Wales

For the history of local government in each country, see:

History of local government in England

History of local government in Northern Ireland

History of local government in Scotland

History of local government in Wales

For local government entities in each country, see

Category:Local authorities of England

Category:Local authorities of Northern Ireland

Category:Local authorities of Scotland

Category:Local authorities of Wales
Paracobitis rhadinaea
Paracobitis rhadinaea, or the Easted crested loach, is a species of stone loach  the Sistan basin of Iran and Helmand River in Afghanistan. This species reaches a length of 23.6 cm (9.3 in). It is known from minor morphological differences between specimens.

Nemacheilidae
The Nemacheilidae, or stone loaches, are a family of cypriniform fishes that inhabit stream environments, mostly in Eurasia, with one genus, Afronemacheilus, found in Africa. The family includes about 790 species.
Silicide carbide
Silicide carbides or carbide silicides are compounds containing anions composed of silicide (Si4−) and carbide (C4−) or clusters therof. They can be considered as mixed anion compounds or intermetallic compounds, as silicon could be considered as a semimetal.

Related compounds include the germanide carbides, phosphide silicides, boride carbides and nitride carbides. Other related compounds may contain more condensed anion combinations such as the carbidonitridosilicates with C(SiN3)4 with N bridging between two silicon atoms.

Mixed-anion compounds
Mixed-anion compounds, heteroanionic materials or mixed-anion materials are chemical compounds containing cations and more than one kind of anion. The compounds contain a single phase, rather than just a mixture.
Lenvatinib
Lenvatinib, sold under the brand name Lenvima among others, is an anti-cancer medication for the treatment of certain kinds of thyroid cancer and for other cancers as well. It was developed by Eisai Co. and acts as a multiple kinase inhibitor against the VEGFR1, VEGFR2 and VEGFR3 kinases.

Everolimus
Everolimus, sold under the brand name Afinitor among others, is a medication used as an immunosuppressant to prevent rejection of organ transplants and as a targeted therapy in the treatment of renal cell cancer and other tumours.

This compound also has a use in cardiovascular drug-eluting stent technologies to inhibit restenosis.

It is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin (mTOR).

It is marketed by Novartis under the trade names Zortress (US) and Certican (European Union and other countries) in transplantation medicine, and as Afinitor (general tumours) and Votubia (tumours as a result of Tuberous Sclerosis Complex (TSC)) in oncology.

It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication.
Sharon Statement
The Sharon Statement is the founding statement of principles for Young Americans for Freedom. The views expressed in the statement, while not considered "traditional conservative principles" at the time, played a significant role in influencing Republican leaders in the 1980s. Written by M. Stanton Evans and adopted on September 11, 1960, the statement is named for the location of the inaugural meeting of Young Americans for Freedom, held at William F. Buckley, Jr.'s childhood home in Sharon, Connecticut.

Sharon, Connecticut
Sharon is a town in Litchfield County, Connecticut, United States, in the northwest corner of the state. At the time of the 2020 census, the town had a total population of 2,680. The town is part of the Northwest Hills Planning Region. The ZIP Code for Sharon is 06069. The urban center of the town is the Sharon census-designated place, with a population of 729 at the 2010 census.
Carex liparocarpos
Carex liparocarpos is a species of sedge (genus Carex), native to southern Europe, and the Atlas and Caucasus regions. It is typically found growing in sandy steppes, dunes, riverine gravel deposits, and scree.

Carex
Carex is a vast genus of over 2,000 species of grass-like plants in the family Cyperaceae, commonly known as sedges (or seg, in older books). Other members of the family Cyperaceae are also called sedges; however, those of genus Carex may be called true sedges. Carex is the most species-rich genus in the family. The study of Carex is known as caricology.
2012 North Carolina Senate election
The 2012 North Carolina State Senate elections selected members to serve in the North Carolina Senate for a two-year term commencing in January 2013. Going into the election, the Senate had 31 Republican and 19 Democratic members, which constituted a two-thirds super-majority for the Republican Party. Following the election, the Senate had 33 Republican and 17 Democratic members.

Haywood County, North Carolina
Haywood County is a county located in the U.S. state of North Carolina. As of the 2020 census, the population was 62,089. The county seat and its largest community is Waynesville.

Haywood County is part of the Waynesville, NC Micropolitan Statistical Area.
Sakanoue no Tamuramaro
Sakanoue no Tamuramaro (坂上 田村麻呂; Japanese pronunciation: [sa.ka.noꜜ.ɯ.e no | ta.mɯ.ɾaꜜ.ma.ɾo], 758 – June 17, 811) was a court noble, general and shōgun of the early Heian period of Japan. He served as Dainagon, Minister of War and Ukon'e no Taisho (Major Captain of the Right Division of Inner Palace Guards). He held the kabane of Ōsukune and the court rank of Junior Second Rank and was awarded the Order of Second Class.

He was the son of Sakanoue no Karitamaro. He was considered an avatar of Bishamonten in legend.

Vaiśravaṇa
Vaiśravaṇa (Sanskrit: वैश्रवण) or Vessavaṇa (Pali; Tibetan: རྣམ་ཐོས་སྲས་, Lhasa dialect: [Namtösé], simplified Chinese: 多闻天王; traditional Chinese: 多聞天王; pinyin: Duōwén Tiānwáng, Japanese: 毘沙門天, romanized: Bishamonten) is one of the Four Heavenly Kings, and is considered an important figure in Buddhism. He is the god of warfare and usually portrayed as a warrior-king. Vaiśravana is based on Kubera, the Hindu deity of wealth.
Greenbrier, Alabama
Greenbrier is an unincorporated community in south eastern Limestone County, Alabama, United States. The population is 30 as of 2020. It is located 5.5 kilometers from the Madison County and Limestone County borders.

Madison County, Alabama
Madison County is a county located in the north central portion of the U.S. state of Alabama. As of the 2020 Census, the population was 388,153, and according to a 2023 population estimate the county has become the second-most populous county in Alabama after only Jefferson County, home to Birmingham. Its county seat is Huntsville. Since the mid-20th century it has become an area of defense and space research and industry. The county is named in honor of James Madison, fourth President of the United States and the first President to visit the state of Alabama. Madison County covers parts of the former Decatur County. Madison County is included in the Huntsville, Alabama Metropolitan Statistical Area.
Hymenandra
Hymenandra is a genus of flowering plants belonging to the family Primulaceae.

Its native range is Assam to Southern Central China and Western Malesia, Central America to Colombia.

Species:

Hymenandra acutissima (Cuatrec.) Pipoly & Ricketson

Hymenandra beamanii B.C.Stone

Hymenandra calcicola (Furtado) B.C.Stone

Hymenandra callejasii (Pipoly) Pipoly & Ricketson

Hymenandra calycosa (Hemsl.) Pipoly & Ricketson

Hymenandra crosbyi (Lundell) Pipoly & Ricketson

Hymenandra diamphidia B.C.Stone

Hymenandra iteophylla (Ridl.) Furtado

Hymenandra lilacina B.C.Stone

Hymenandra narayanaswamii M.P.Nayar & G.S.Giri

Hymenandra pittieri (Mez) Pipoly & Ricketson

Hymenandra rosea B.C.Stone

Hymenandra sordida (Lundell) Pipoly & Ricketson

Hymenandra squamata (Lundell) Pipoly & Ricketson

Hymenandra stenophylla (Donn.Sm.) Pipoly & Ricketson

Hymenandra wallichii A.DC.

Primulaceae
The Primulaceae (/ˌprɪmjəˈleɪʃi.iː/ PRIM-yə-LAY-shee-ee), commonly known as the primrose family (but not related to the evening primrose family), are a family of herbaceous and woody flowering plants including some favourite garden plants and wildflowers. Most are perennial though some species, such as scarlet pimpernel, are annuals.

Previously one of three families in the order Primulales, it underwent considerable generic re-alignment once molecular phylogenetic methods were used for taxonomic classification. The order was then submerged in a much enlarged order Ericales and became a greatly enlarged Primulaceae sensu lato (s.l). In this new classification of the Angiosperm Phylogeny Group, each of the Primulales families was reduced to the rank of subfamily of Primulaceae s.l. The original Primulaceae (Primulaceae sensu stricto or s.s.) then became subfamily Primuloideae, and one genus (Maesa) was raised to the rank of a separate subfamily, making four in all.
Seussical
Seussical, sometimes Seussical the Musical, is a musical with lyrics by Lynn Ahrens, music by Stephen Flaherty, and a story co-written by both. It is based on the works of Dr. Seuss, with most of its plot drawing from Horton Hears a Who!, Gertrude McFuzz, and Horton Hatches the Egg. The title is a portmanteau of "Seuss" and "musical". Despite a negative critical reception and significant financial losses during its initial Broadway run in 2000, Seussical has since had a revival in popularity, with two US national tours, a West End production, and numerous adaptations for schools and regional theaters.

The Butter Battle Book
The Butter Battle Book is a children's book written and illustrated by Dr. Seuss and published by Random House on January 12, 1984. It is an anti-war story; specifically, a parable about arms races in general, mutually assured destruction and nuclear weapons in particular. The Butter Battle Book was a New York Times Notable Book of the Year.

This book was written during the Cold War era and reflects the concerns of the time, regarding the perceived possibility that humanity could be destroyed in a nuclear war. It can also be seen as a satirical work, with its depiction of a deadly war based on a senseless conflict over something as trivial as a breakfast food.
Dilek Sabancı Sport Hall
Dilek Sabancı Sport Hall (Turkish: Dilek Sabancı Spor Salonu) was an indoor sporting arena located in Antalya, Turkey. Owned by the Sabancı Foundation, it was opened on November 3, 2001.

The capacity of the arena was 2,500 spectators.  It was the home of Turkish Basketball League clubs, Antalya Büyükşehir Belediyesi and Kepez Belediyespor. The arena was demolished in June 2013 due to construction of New Antalya Stadium, and replaced by a new arena originally being built for the 2010 FIBA World Championship, Antalya Arena.

Antalya Stadium
The Antalya Stadium, officially branded as Corendon Airlines Park for sponsorship reasons, is a multi-purpose stadium in Antalya, Turkey. It is used mostly for football matches, hosting Turkish Süper Lig club Antalyaspor home matches. It has a capacity of nearly 32,537 (all seated) and is totally covered. The stadium has solar panels on its rooftop which generates, on average 7,200 kWh a day, enough to produce its total monthly electricity usage.
Journal of Environmental Economics and Management
The Journal of Environmental Economics and Management is a peer-reviewed academic journal of environmental economics published six times per year. It was the official journal of the Association of Environmental and Resource Economists until 2014. The journal is generally regarded as the top journal in natural resources and environmental economics, and publishes theoretical and empirical papers concerned with the linkage between economic systems and environmental and natural resources. Ralph d'Arge and Allen V. Kneese were the founding editors. The current editors-in-chief are Roger von Haefen (North Carolina State University) and Andreas Lange (University of Hamburg). Previous editors include Till Requate, Daniel J. Phaneuf, Joseph Herriges, and Charles F. Mason.

Environmental economics
Environmental economics is a sub-field of economics concerned with environmental issues. It has become a widely studied subject due to growing environmental concerns in the twenty-first century. Environmental economics "undertakes theoretical or empirical studies of the economic effects of national or local environmental policies around the world. Particular issues include the costs and benefits of alternative environmental policies to deal with air pollution, water quality, toxic substances, solid waste, and global warming."
Leitis in Waiting
Leitis In Waiting is a 2018 feature-length documentary about transgender rights in Tonga. It was produced and directed by Dean Hamer, Joe Wilson and Hinaleimoana Wong-Kalu. The filmmakers previously explored trans rights in the Pacific in their films Kumu Hina and A Place in the Middle.

Kumu Hina
Kumu Hina is a 2014 American LGBTQ related documentary film co-produced and co-directed by Dean Hamer and Joe Wilson. It is based on the story of Hina Wong-Kalu, and stars Wong-Kalu, Haemaccelo Kalu and Hoʻonani Kamai. The film premiered at the Hawaii International Film Festival on April 10, 2014, and had its television debut on Independent Lens in May 2015.
IRAS 14026+4341
IRAS 14026+4341 is a Seyfert type 1 galaxy located in the constellation of Canes Venatici. The redshift of the object is (z) 0.322 and it was first discovered as an infrared source from the Infra Red Astronomical Satellite (IRAS) catalogue in 1987 and later identified as a quasar in 1988. This object is classified as a hyperluminous infrared galaxy due to its extreme luminosity and also a broad absorption-line quasar.

Canes Venatici
Canes Venatici (/ˈkeɪniːz vɪˈnætɪsaɪ/ KAY-neez vin-AT-iss-eye) is one of the 88 constellations designated by the International Astronomical Union (IAU). It is a small northern constellation that was created by Johannes Hevelius in the 17th century. Its name is Latin for 'hunting dogs', and the constellation is often depicted in illustrations as representing the dogs of Boötes the Herdsman, a neighboring constellation.

Cor Caroli is the constellation's brightest star, with an apparent magnitude of 2.9. La Superba (Y CVn) is one of the reddest naked-eye stars and one of the brightest carbon stars. The Whirlpool Galaxy is a spiral galaxy tilted face-on to observers on Earth, and was the first galaxy whose spiral nature was discerned. In addition, quasar TON 618 is one of the most massive black holes with the mass of 66 billion solar masses.
Mandan Commercial Historic District
Mandan Commercial Historic District is a 20-acre (8.1 ha) historic district in Mandan, North Dakota that has work dating to 1884.  It was listed on the National Register of Historic Places (NRHP) in 1985.  The listing includes 35 contributing buildings and a contributing object.

It includes the Sullivanesque Lewis and Clark Hotel built in 1917, which is separately NRHP-listed.

Mandan was a major hub of the Northern Pacific Railway;  it became headquarters of NP's Missouri Division in 1916.

Mandan, North Dakota
Mandan is a city on the eastern border of Morton County, North Dakota, United States. Founded in 1879 on the west side of the upper Missouri River, it was designated in 1881 as the county seat of Morton County. The population was 24,206 at the 2020 census, and was estimated at 24,788 in 2024, making it the eighth-most populous city in North Dakota. Across the Missouri River from Bismarck. Mandan is a core city of the Bismarck metropolitan area.
Vatican News
Vatican News is the official news portal of the Holy See, serving as a source of information about the activities, pronouncements, and events related to the global Catholic Church and the operations of the Holy See. As a part of the Dicastery for Communication, it plays a central role in disseminating multimedia content that is relevant to the Catholic Church's followers, as well as the broader public interested in Vatican affairs. It brings together Vatican Radio, L'Osservatore Romano and Vatican Media.

The Dicastery for Communication, which oversees Vatican News, is responsible for supervising various communication channels within the Holy See. These channels include Vatican Radio, L'Osservatore Romano (the Vatican's daily newspaper), and Vatican Media, all of which collectively contribute to the comprehensive multimedia coverage of the Vatican's activities. It is based with Vatican Radio at Piazza Pia n. 3 in Vatican City.

Vatican Media
Vatican Media, formerly Centro Televisivo Vaticano (lit. 'Vatican Television Centre') from 1983 to 2017, is the national broadcaster of the Holy See. It first aired in 1983 and is based in Vatican City.
Mitsuo Nakamura
Mitsuo Nakamura (中村 光夫, Nakamura Mitsuo; 5 February 1911 – 12 July 1988) was the pen-name of a writer of biographies and stage-plays, and a literary critic active in Shōwa period Japan. His real name was Koba Ichirō.

Literary magazine
A literary magazine is a periodical devoted to literature in a broad sense. Literary magazines usually publish a mix of fiction and non-fiction. Short stories and poetry are common literary forms published, but some magazines may publish serial literature—a novel which is revealed in sections over multiple issues. Non-fiction writing may be from staff of the literary magazine to make commentary about their magazine or about culture related to literature. Non-fiction from contributors may take the form of essays, literary criticism, book reviews, biographical profiles of authors, interviews, and letters. Literary magazines are often called literary journals (or little magazines) to contrast them with larger, commercial magazines.
Keith Birdsong
Keith Birdsong (July 14, 1959 – June 4, 2019) was an American illustrator, known best for illustrating covers of Star Trek novels, which usually depicted the various characters of the Star Trek television series and movies in a realistic manner.

The Bradford Exchange
The Bradford Exchange is an American producer and seller of collectible goods, jewelry, sports memorabilia and apparel. Now part of the Bradford Group, it was founded in 1973 as The Bradford Gallery of Collector's Plates by J. Roderick MacArthur. The company created its first live price quotation market in 1983, but increasingly turned to creating new lines of collectibles (rather than just facilitating exchanges between collectors).

The Bradford Group of companies, headquartered in Niles, Illinois, a suburb of Chicago, includes many groups of collectibles, including Ardleigh Elliott, Ashton-Drake Galleries, Bradford Editions, Bradford Exchange, Hamilton Authenticated, the Hamilton Collection and Hawthorne Village. Internationally, they have a presence in Canada, Australia, New Zealand, Germany, Switzerland, Austria, France, Italy, Sweden and the Netherlands.

Under the Ashton-Drake Galleries name, they have sold dolls like Gene Marshall and Blythe as well as Reborn dolls.
Term (logic)
In mathematical logic, a term is an arrangement of dependent/bound symbols that denotes a mathematical object within an expression/formula. In particular, terms appear as components of a formula. This is analogous to natural language, where a noun phrase refers to an object and a whole sentence refers to a fact.

A first-order term is recursively constructed from constant symbols, variable symbols, and function symbols.
An expression formed by applying a predicate symbol to an appropriate number of terms is called an atomic formula, which evaluates to true or false in bivalent logics, given an interpretation.
For example, ⁠⁠ is a term built from the constant 1, the variable x, and the binary function symbols ⁠⁠ and ⁠⁠; it is part of the atomic formula ⁠⁠ which evaluates to true for each real-numbered value of x.

Besides in logic, terms play important roles in universal algebra, and rewriting systems.

Signature (logic)
In mathematical logic, a signature is a description of the non-logical symbols of a formal language. In universal algebra, a signature lists the operations that characterize an algebraic structure. In model theory, signatures are used for both purposes. They are rarely made explicit in more philosophical treatments of logic.
Hyperthyroxinemia
Hyperthyroxinemia is a thyroid disease where the serum levels of thyroxine are higher than expected. Thyroxine or tetraiodothyronine (T4) is produced by the thyroid gland.

The term is sometimes used to refer to hyperthyroidism, but hyperthyroidism is a more general term.

When the level of thyroxine (T4) in the blood exceeds normal range, it can lead to symptoms such as irritability and unexplained weight loss.

Types include:

Familial dysalbuminemic hyperthyroxinemia

Familial euthyroid hyperthyroxinemia

Thyroid hormone resistance syndrome

Thyroid hormone resistance
Thyroid hormone resistance (also resistance to thyroid hormone (RTH), and sometimes Refetoff syndrome) describes a rare syndrome in which the thyroid hormone levels are elevated but the thyroid stimulating hormone (TSH) level is not suppressed, or not completely suppressed as would be expected. The first report of the condition appeared in 1967. Essentially this is decreased end organ responsiveness to thyroid hormones. A new term "impaired sensitivity to thyroid hormone" has been suggested in March 2014 by Refetoff et al.