hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Dihydromethysticin
Dihydromethysticin is one of the six major kavalactones found in the kava plant. It is known for its anxiolytic, analgesic, and anticonvulsant properties. It induces the liver enzymes CYP1A1 and CYP3A through mechanisms involving the aryl hydrocarbon receptor and potentially pregnane X receptor-independent transcriptional activation. Dihydromethysticin acts synergistically with other kavalactones, modulates NMDA receptors and voltage-dependent calcium channels, and functions as a GABAA receptor positive allosteric modulator and monoamine oxidase B inhibitor. Dihydromethysticin shows high systemic exposure and rapid absorption in humans, suggesting it is a major contributor to kava’s effects.

CYP3A
Cytochrome P450, family 3, subfamily A, also known as CYP3A, is a human gene locus. A homologous locus is found in mice. These genes encode monooxygenases which catalyze many reactions involved in the synthesis of cholesterol, steroids and other lipids as well as drug metabolism.

The CYP3A locus includes all the known members of the 3A subfamily of the cytochrome P450 superfamily of genes. The CYP3A cluster consists of four genes:

CYP3A4,

CYP3A5,

CYP3A7, and

CYP3A43.

The region also contains four pseudogenes:

CYP3A51P,

CYP3A52P,

CYP3A54P, and

CYP3A137P.

as well as several extra exons which may or may not be included in transcripts produced from this region. Previously another CYP3A member, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4.
Hans Dobida
Hans Dobida (13 May 1929 – 16 January 2025) was an Austrian ice hockey administrator. Playing ice hockey and on the Austria men's national handball team in early life, he had a lengthy involvement with ATSE Graz while serving as president of the Austrian Ice Hockey Association. He helped Austria organize hosting ice hockey at the Olympic Games  and the Ice Hockey World Championships; and as a member of the International Ice Hockey Federation (IIHF) council, oversaw the IIHF Continental Cup, and sat on the IIHF Inline Hockey World Championship committee. He was inducted into the IIHF Hall of Fame, the German Ice Hockey Hall of Fame, and the Slovenian Hockey Hall of Fame, and received the Decoration of Honour for Services to the Republic of Austria.

German Ice Hockey Hall of Fame
The German Ice Hockey Hall of Fame German: Eishockeymuseum was founded in 1988, and is located in Augsburg. The hall honors individuals who have contributed to ice hockey in Germany, and displays memorabilia depicting contributions of players, coaches, referees, and other important figures in the sport.
Victory Party (Argentina)
The Victory Party (Spanish: Partido de la Victoria) is a minor Kirchnerist political party in Argentina founded in 2003 by Néstor Kirchner and Diana Conti to group independent sectors (those who were not aligned with the Justicialist Party) of the Kirchnerist coalition. The party now forms part of the Unión por la Patria, the former ruling coalition supporting then- President Alberto Fernández and supported Sergio Massa's presidential campaign. The party was a founding member of the similarly named Front for Victory, the coalition that led Néstor Kirchner to the presidency in the 2003 election.

Homeland Force
The Homeland Force (Spanish: Fuerza Patria, FP), also known as the Union for the Homeland (Spanish: Unión por la Patria, UP or UxP) until 2025, is a centre-left to left-wing political and electoral coalition of Peronist political parties in Argentina. It has been the main opposition coalition since December 2023.

The coalition was formed to compete in the 2023 general election, and is a successor to the previous Frente de Todos coalition, whose candidate in the 2019 presidential election, Alberto Fernández, was successfully elected President of Argentina. The coalition is centred on the Justicialist Party and its allies both on the federal and provincial levels, including the Renewal Front of Sergio Massa, who was the coalition's unsuccessful candidate for president in the 2023 presidential election.
Kate Boutilier
Kate Boutilier is an American screenwriter and producer whose credits include the animated television series Rugrats, The Wild Thornberrys, All Grown Up! and Holly Hobbie & Friends, and the feature films The Wild Thornberrys Movie, Rugrats Go Wild, and Rugrats in Paris. She co-created and produced the series Poppy Cat and The Mr. Men Show, and co-showran the Rugrats reboot.

Rugrats (2021 TV series)
Rugrats is an American animated television series created by Arlene Klasky, Gábor Csupó, and Paul Germain. It has been described as a reboot of the original TV series of the same name which aired from 1991 to 2004. The series premiered on May 27, 2021, on Paramount+; it is the second Nickelodeon-based series created for the streaming service. As with previous incarnations of the franchise, the series was produced by Klasky Csupo and Nickelodeon Animation Studio.

On March 28, 2024, the series was removed from Paramount+ as part of a "strategic decision to focus on content with mass global appeal." Premieres had already moved to the Nicktoons channel on March 14, 2024.

A third season was produced, but it went unaired for reasons unknown.
Five & Two Pictures
Five & Two Pictures is an independent Christian film production company founded in 2002 by Dave Christiano and Rich Christiano. They have produced several Christian feature films; Time Changer, Unidentified, Me & You, Us, Forever, The Secrets of Jonathan Sperry, Amazing Love, Play the Flute and A Matter of Faith.

The Secrets of Jonathan Sperry
The Secrets of Jonathan Sperry is a 2008 Christian film, released to theaters on September 18, 2009. It was directed by Rich Christiano, and the majority of the film was filmed in Holley, New York, beginning August 18, 2007. The film premiered at the Merrimack Valley Christian Film Festival. Gavin MacLeod (in his final film role before his death), who also starred in The Love Boat and The Mary Tyler Moore Show plays the lead role in the film.
Evarcha certa
Evarcha certa is  a species of jumping spider in the genus Evarcha that lives in Guinea and Ethiopia. It thrives in grasslands, particularly near bodies of water like the Baro River and in areas of high altitude such as the Guinea Highlands. The species was first described in 2002 by Christine Rollard and Wanda Wesołowska. The spider is small, with a cephalothorax measuring between 2.6 and 2.9 mm (0.10 and 0.11 in) long and an abdomen that is between 2.7 and 3.4 mm (0.11 and 0.13 in) long. The cephalothorax has a reddish-brown topside, or carapace, with a darker eye field, and an orange underside, or sternum. The abdomen has a pattern consisting of irregular brown patches, although this differs between individual spiders. The spider has orange or yellow legs. It has  distinctive copulatory organs. The female has relatively simple spermathecae that are heavily sclerotized and short insemination ducts. The male has not been described.

Baro River
The Baro River (Amharic: ባሮ ወንዝ) or Baro/Openo Wenz, known to the Anuak as Openo River, is a river in southwestern Ethiopia, which defines part of Ethiopian border with South Sudan. From its source in the Ethiopian Highlands it flows west for 306 kilometres (190 mi) to join the Pibor River. The Baro-Pibor confluence marks the beginning of the Sobat River, a tributary of the White Nile.

The Baro and its tributaries drain a watershed 41,400 km2 (16,000 sq mi) in size. The river's mean annual discharge at its mouth is 241 m³/s (8,510 ft³/s).
1972 Argentine Primera División
The 1972 Primera División season was the 81st season of top-flight football in Argentina. Banfield was penalised with a 4-month suspension and the subsequent points deduction after a proved bribe. The case referred back to the 1971 Metropolitano when Banfield was about to be relegated along with Los Andes. A Banfield executive offered Ferro Carril Oeste players (their rivals in the last fixture of the tournament) a high amount of money to fix the match. Nevertheless, the meeting was reported to the police who arrested the executive. Banfield would be then penalised by the AFA.

With Lanús (1970 Primera B Metropolitana champions) as the only team promoted from the lower division, San Lorenzo won both tournaments, Metropolitano and Nacional (9th and 10th league titles). San Lorenzo and River Plate (Torneo Nacional champion and runner-up) qualified for the 1973 Copa Libertadores. On the other hand, Banfield and Lanús were relegated via Torneo Reclasificatorio.

1971 Argentine Primera División
The 1971 Primera División season was the 80th season of top-flight football in Argentina. The Campeonato Metropolitano championship was modified, returning to a double round-robin format, and four relegations. Nevertheless, the AFA interventor, Raúl D'Onofrio (the 4th interventor since the military dictatorship led by Juan Carlos Onganía removed Valentín Suárez from the Association), reduced the number of relegated teams to two.

The entire season ran from 5 March to 29 December. As champion of 1970 Primera B, Ferro Carril Oeste promoted to Primera División. Independiente (10th title) won the Metropolitano and Rosario Central (coached by Ángel Labruna, not only won the 1st league title for the club but the first for a team outside Buenos Aires) won the Nacional championship. Moreover, both clubs qualified for the 1972 Copa Libertadores (in the case of Independiente, after winning the first "Liguilla pre-Libertadores" edition v San Lorenzo).

Los Andes and Platense were relegated.
Sonder (company)
Sonder Holdings Inc. was a company that managed short-term rentals, such as apartment hotels, in North America, Europe, and Dubai. It was founded in Montreal, Canada in 2014 and after 2016 was based in San Francisco, California.

Sonder managed over 9,000 units in over 40 cities and served over 1 million guests. Although it competed with Airbnb, Sonder leased and managed its own rentals. It targeted travelers who prefer larger accommodations than a hotel room but wanted a more predictable experience than renting from an amateur host. Guests used a mobile app to check in and get customer support. The company outsourced maintenance and housekeeping services. Guests could request this service via its app.

Following loss of business from the COVID-19 pandemic and an unsuccessful partnership with Marriott International, Sonder filed for Chapter 7 bankruptcy in November 2025.

Chapter 7, Title 11, United States Code
Chapter 7 of Title 11 U.S. Code is the bankruptcy code that governs the process of liquidation under the bankruptcy laws of the United States. This is in contrast to bankruptcy under Chapter 11 and Chapter 13, which govern the process of reorganization of a debtor. Chapter 7 bankruptcy is the most common form of bankruptcy in the US.
The Country Boy (film)
The Country Boy is a lost 1915 American comedy silent film directed by Frederick A. Thomson based upon a play by Edgar Selwyn. The film stars Marshall Neilan, Florence Dagmar, Dorothy Green, Loyola O'Connor, Mrs. Lewis McCord, and Horace B. Carpenter. The film was released on February 18, 1915, by Paramount Pictures.

Horace B. Carpenter
Horace B. Carpenter (January 31, 1875 – May 21, 1945) was an American actor, film director, and screenwriter. He appeared in more than 330 films between 1914 and 1945. He also directed 15 films between 1925 and 1934. Born in Grand Rapids, Michigan, Carpenter died in Hollywood, California, from a heart attack.
Erin Lavik
Erin Baker Lavik (born 1973) is an American bioengineer serving as the deputy director and chief technology officer of the National Cancer Institute's Division of Cancer Prevention (DCP) since 2023. She was previously a professor of chemical, biochemical, and environmental engineering at the University of Maryland, Baltimore County. Lavik develops polymers and nanoparticles that can protect the nervous system. She is a fellow of the American Institute for Medical and Biological Engineering.

American Institute for Medical and Biological Engineering
The American Institute for Medical and Biological Engineering (AIMBE) is a non-profit organization founded in 1991, and headquartered in Washington, D.C. It represents 50,000 medical and biomedical engineers, and academic institutions, private industry, and professional engineering societies.
Bruce Irons (surfer)
Bruce Irons (born November 16, 1979) is an American regularfoot professional surfer from Hanalei, Kauai, and is often regarded as one of the best tuberiders of all time. He is the younger brother of three-time world champion Andy Irons.

Hanalei, Hawaii
Hanalei is a census-designated place (CDP) in Kauaʻi County, Hawaii, United States. The population was estimated at 299 as of 2019. Hanalei means "lei making" in Hawaiian. Alternatively, the name Hanalei also means "crescent bay" and may be indicative of the shape of Hanalei Bay. Hanalei can also be translated as lei valley, referring to the rainbows that color the valley and encircle Hanalei like a wreath.
Propylparaben
Propylparaben (also spelled propyl paraben) is the n-propyl ester of p-hydroxybenzoic acid. It occurs as a natural substance found in many plants and some insects. Additionally, it can be manufactured synthetically for use in cosmetics, pharmaceuticals, and foods. It is a member of the class of parabens and can be used as a preservative in many water-based cosmetics, such as creams, lotions, shampoos, and bath products. As a food additive, it has the E number E216.

Sodium propyl p-hydroxybenzoate, the sodium salt of propylparaben, a compound with formula Na(C3H7(C6H4COO)O), is used similarly as a food additive and as an anti-fungal preservation agent. Its E number is E217.

In 2010, the European Union Scientific Committee on Consumer Safety stated that the use of butylparaben and propylparaben as preservatives in finished cosmetic products is safe to the consumer, as long as the sum of their concentrations does not exceed 0.19%.

E number
E numbers, short for Europe numbers, are codes for substances used as food additives, including those found naturally in many foods, such as vitamin C, for use within the European Union (EU): 27  and European Free Trade Association (EFTA). Commonly found on food labels, their safety assessment and approval are the responsibility of the European Food Safety Authority (EFSA). The fact that an additive has an E number implies that its use was at one time permitted in products for sale in the European Single Market; some of these additives are no longer allowed today.

Having a single unified list for food additives was first agreed upon in 1962 with food colouring. In 1964, the directives for preservatives were added; In 1970 antioxidants were added; In 1974 emulsifiers, stabilisers, thickeners and gelling agents were added as well.
Filth (Swans album)
Filth is the debut studio album by American experimental rock band Swans. It was released in 1983 through Neutral Records, following the release of the band's self-titled debut EP in 1982. Though it did not receive much contemporary attention, Filth has since been recognized as ahead of its time and significant to heavy genres of music.

Musically, the album is bleak, grinding, and deliberately repetitive, defined by two bassists persistently doubling over the same chord. The two drummers, Jonathan Kane and Roli Mosimann, play chaotically and angularly, occasionally mixing in percussion from metal straps striking tables, and the distorted guitar of Norman Westberg plays in a grating fashion. The vocals of Swans frontman Michael Gira are scathing and direct, covering topics of social decay, corruption, rape, and abuse of power.

Michael Gira
Michael Rolfe Gira (/dʒəˈrɑː/; born February 19, 1954) is an American singer-songwriter, composer, author and artist. Now based in New Mexico, he founded the band Swans, in which he sings and plays guitar, in New York City in the 1980s at the height of the no wave movement. He is also the founder of Young God Records and previously fronted Angels of Light.
Sarilumab
Sarilumab, sold under the brand name Kevzara, is a human monoclonal antibody medication against the interleukin-6 receptor. Regeneron Pharmaceuticals and Sanofi developed the drug for the treatment of rheumatoid arthritis (RA), for which it received US FDA approval on 22 May 2017 and European Medicines Agency approval on 23 June 2017.

Development in ankylosing spondylitis has been suspended after the drug failed to show clinical benefit over methotrexate in a phase II trial.

Interleukin 6
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene.

In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation.  Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine.  IL-6's role as an anti-inflammatory myokine is mediated through its inhibitory effects on TNF and IL-1 and its activation of IL-1ra and IL-10.

There is some early evidence that IL-6 can be used as an inflammatory marker for severe COVID-19 infection with poor prognosis, in the context of the wider coronavirus pandemic.
Thayi Illada Thabbali
Thayi Illada Thabbali  (transl. Motherless orphan) is a 2003 Indian Kannada-language drama film written and directed by Om Sai Prakash. The film was produced by Ramesh Yadav under the banner Royal Pictures. It features Shivadwaj and Radhika. The score and soundtrack for the film is by Nadabrahma Hamsalekha  and the cinematography is by Sundarnath Suvarna. Radhika received Karnataka State Award for Best Actress for her performance and she also received nomination for Filmfare Award for Best Actress - Kannada.

Hamsalekha
Gangaraju (born June 23, 1951), professionally known as Hamsalekha, is an Indian film composer and songwriter who works in South Indian cinema, predominantly in the Kannada film industry since the late 1980s. He is also a screenplay writer, dialogue writer, instrumentalist and conductor, having composed and written over 500 albums.

Hamsalekha has won one National Film Award, six Filmfare Awards in the Best Music Director Category, seven Karnataka State Film Awards - four for music direction and three for lyrics - and is a recipient of an honorary doctorate from Bangalore University. His collaboration with V. Ravichandran resulted in producing blockbuster soundtracks in mainstream Kannada cinema.
Linda Burgess
Linda Gail Burgess (born July 27, 1969) is an American former professional basketball player. She played college basketball for the Alabama Crimson Tide and professionally in the Women's National Basketball Association (WNBA) for the Los Angeles Sparks and Sacramento Monarchs.

Alabama Crimson Tide women's basketball
The Alabama Crimson Tide women's basketball program represents the University of Alabama in the sport of women's basketball. The team competes in the Southeastern Conference and National Collegiate Athletic Association. They are coached by eighth-year head coach Kristy Curry.
Anjali Bhardwaj
Anjali Bhardwaj (born 1973) is an Indian social activist working on issues of transparency and accountability. She is a co-convenor of the National Campaign for People's Right to Information (NCPRI) and a founding member of Satark Nagrik Sangathan. She works on issues related to right to information, Lokpal, whistleblower protection, grievance redress, and right to food.

National Campaign for People's Right to Information
National Campaign for People's Right to Information (NCPRI) was established in 1996 to advocate for a legal backing to citizens right to information. This resulted in the historic and pro-people law - the Right to Information Act, 2005. More recently, this movement has also campaigned for Grievance redressal bill and Whistleblowers protection bill. It is a network of organisations and individuals who use the Right to Information law to demand transparency and accountability of government, but also support the use of the RTI in various other sectors to demand accountability.
Take a Letter Maria
"Take a Letter Maria" is the debut single written and recorded by American soul singer R. B. Greaves. It was recorded at Muscle Shoals Sound Studio on August 19, 1969, using the house studio musicians. These include Donna Jean Thatcher on vocals (later Donna Jean Godchaux of the Grateful Dead), Roger Hawkins on drums, Barry Beckett on electric piano, Eddie Hinton and Jimmy Johnson on guitar, David Hood on bass, and Mel Lastie on trumpet. 
"Take a Letter Maria" was released in September 1969, and quickly gained regular airplay. The single peaked at No. 2 on the Billboard Hot 100, and was kept from the top spot by the 5th Dimension's "Wedding Bell Blues". It was the last #2 hit of the 1960s.

The single was certified gold by November 1969; one million copies had shipped.  By 1970, sales totalled 2.5 million.

Roger Hawkins (drummer)
Roger G. Hawkins (October 16, 1945 – May 20, 2021) was an American drummer best known for playing as part of the studio backing band known as the Muscle Shoals Rhythm Section (also known as the Swampers) of Alabama. Rolling Stone ranked Hawkins number 31 on its list of greatest drummers.
Epichloë pampeana
Epichloë pampeana is a hybrid asexual species in the fungal genus Epichloë.

A systemic and seed-transmissible grass symbiont first described in 2009, Epichloë pampeana is a natural allopolyploid of Epichloë festucae and a strain from the Epichloë typhina complex (from Poa nemoralis).

Epichloë pampeana is found in South America, where it has been identified in the grass species Bromus auleticus.

Epichloë festucae
Epichloë festucae is a systemic and seed-transmissible endophytic fungus of cool season grasses.

First described in 1994, Epichloë festucae is a sister lineage to Epichloë amarillans, Epichloë baconii, Epichloë mollis and Epichloë stromatolonga. Epichloë festucae is found across North America, where it lives in the grass species Bromus kalmii and Elymus spp. (including Elymus patula).
Tiémoko Konaté
Tiémoko Konaté (born 3 March 1990) is an Ivorian professional footballer who plays as a winger.

Konaté started out his career in his native Ivory Coast before a prolific period at Czech club Sparta Prague where he would play for six years, winning the Czech First League championship and the Czech Cup in 2014.

A dynamic winger, he is known for his agility and strong technique.

AC Sparta Prague
Athletic Club Sparta Praha (Czech pronunciation: [ˈaː ˈtsɛː ˈsparta ˈpraɦa]), commonly known as Sparta Prague and Sparta Praha, is a professional football club based in Prague.

It is the most successful club in the Czech Republic and one of the most successful in central Europe, winning the central European Cup (also known as the Mitropa Cup) three times and reaching the semi-finals of the European Cup (now the UEFA Champions League) in 1992 and the UEFA Cup Winners' Cup in 1973.

Sparta have won a record 38 domestic league titles, a record 16 Czech Cups (and its predecessor Czechoslovak Cup), and two Czech Supercups. Sparta was long the main source for the Czech Republic national football team; however, lately the best Czech players almost exclusively play in foreign leagues.

Sparta plays at Prague's Epet Arena, also known as Letná Stadium.