hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Isonipecotic acid
Isonipecotic acid, also known as piperidine-4-carboxylic acid (P4C), is a conformationally constrained derivative of γ-aminobutyric acid (GABA) and a moderately potent GABAA receptor partial agonist. It consists of a piperidine ring with a carboxylic acid moiety in the iso position. The drug showed moderate-efficacy partial agonism of α1, α2, α3, and α5 subunit-containing GABAA receptors (EmaxTooltip maximal efficacy = 46–57%), but showed full or near-full agonism of α4 and α6 subunit-containing GABAA receptors (Emax = 83–104%). Isonipecotic acid is unable to cross the blood–brain barrier. It was first described in the scientific literature by at least 1944 and was identified as a GABAA receptor agonist by 1978.

Intrinsic activity
Intrinsic activity (IA) and maximal efficacy (Emax) refer to the relative ability of a drug-receptor complex to produce a maximum functional response. This must be distinguished from the affinity, which is a measure of the ability of the drug to bind to its molecular target, and the EC50, which is a measure of the potency of the drug and which is proportional to both efficacy and affinity. This use of the word "efficacy" was introduced by Stephenson (1956) to describe the way in which agonists vary in the response they produce, even when they occupy the same number of receptors. High efficacy agonists can produce the maximal response of the receptor system while occupying a relatively low proportion of the receptors in that system. There is a distinction between efficacy and intrinsic activity.
Homies (musical group)
Homies (Korean: 호미들; RR: Homideul) is a South Korean hip hop group composed of Chin, CK, and Louie. They first garnered attention when they appeared on the YouTube hip hop audition program Superbee's Rap Academy in 2019.

They signed to Yng & Rich Records in 2020 where they released the studio album Generation (2021) and extended plays Ghetto Superstars (2020) and Family Business (2021). They won 1 Gaon Chart Music Awards, 1 Melon Music Awards, and 2 Korean Hip-hop Awards.

Melon Music Awards
The Melon Music Awards (Korean: 멜론 뮤직어워드) is a major music awards show that is held annually by Kakao Entertainment (a Kakao company) through its online music store Melon. The event was initially a fan-voted award conducted entirely online from 2005 through 2008, and has been officially held offline in Seoul since 2009.

The award show uses digital data from the Melon music platform, online voting and judges' evaluation—to base its awards on artists who have performed exceptional during the year.
Vladimir Bibikhin
Vladimir Veniaminovich Bibikhin (29 August 1938, Bezhetsk — 12 December 2004, Moscow) was the most prominent Soviet and Russian religious thinker of the New Russia and continued the Russian tradition of early 20th century religious thinking. He was known as a translator, philologist, and philosopher. He is best known for translations of Martin Heidegger, which caused mixed reactions among specialists. He lectured in authors' courses at the philosophy faculty of Moscow State University. Bibikhin undertook a sufficient number of translations to enable him to formulate his own theory of Europe. This theory consisted in part of a return to the past, and enlivening the most valuable achievements of the past culture.

Aleksei Losev
Aleksei Fyodorovich Losev (Russian: Алексе́й Фёдорович Ло́сев; 22 September 1893 – 24 May 1988) was a Soviet and Russian philosopher, philologist and culturologist, one of the most prominent figures in Russian philosophical and religious thought of the 20th century.
Gwido Langer
Lt. Col. Karol Gwido Langer (Zsolna, Austria-Hungary, 2 September 1894 – 30 March 1948, Kinross, Scotland) was, from at least mid-1931, chief of the Polish General Staff's Cipher Bureau, which from December 1932 decrypted Germany's military Enigma-machine ciphers.

Poland's prewar achievements paved the way for Britain's World War II Ultra secret.

Kinross
Kinross (/kɪnˈrɒs/, Scottish Gaelic: Ceann Rois) is a burgh in Perth and Kinross, Scotland, around 13 miles (21 kilometres) south of Perth and around 20 miles (32 kilometres) northwest of Edinburgh. It is the traditional county town of the historic county of Kinross-shire.
Anime Midwest
Anime Midwest is an annual three-day anime convention held during July at the Hyatt Regency O'Hare and Donald E. Stephens Convention Center in Rosemont, Illinois. The convention is held in the same location as Anime Central.

Rosemont, Illinois
Rosemont is a village in Cook County, Illinois, United States, located immediately northwest of Chicago. As of the 2020 census, the village had a population of 3,952. The village was incorporated in 1956, though it had been settled long before that. While Rosemont's land area and population are relatively small among municipalities in the Chicago metropolitan area, the village is a major center for commercial activity in the region and is a key component of the Golden Corridor. It contains Allstate Arena, which hosts the Chicago Wolves AHL hockey team. Since its founding, the village has been governed by one family, and has been described as America's "last true political machine".
Ladder to the Moon
Ladder to the Moon is a United Kingdom-based social enterprise that works with healthcare organisations to enhance the quality of residential care for those living with dementia and old age, through the use of creativity, coaching, training and consultancy.

Elderly care
Elderly care, or simply eldercare (also known in parts of the English-speaking world as aged care), serves the needs of old adults. It encompasses assisted living, adult daycare, long-term care, nursing homes (often called residential care), hospice care, and home care.

Elderly care emphasizes the social and personal requirements of senior citizens who wish to age with dignity while needing assistance with daily activities and with healthcare. Much elderly care is unpaid.

Elderly care includes a broad range of practices and institutions, as there is a wide variety of elderly care needs and cultural perspectives on the elderly throughout the world.
Caledonian Railway 812 and 652 Classes
The Caledonian Railway 812 and 652 Classes were 0-6-0 steam tender locomotives designed by John F. McIntosh: Intended for express-freight and mixed traffic for the Caledonian Railway and introduced in 1899. They had a huge boiler same boiler type as the 721 “Dunalastair” Class 4-4-0s working at 160 psi which was also fitted with additional tubes allowing it to be a prodigious raiser of steam. They could easily reach speeds of up to 55 mph (89 km/h).

4-4-0
4-4-0, in the Whyte notation, denotes a steam locomotive with a wheel arrangement of four leading wheels on two axles (usually in a leading bogie), four powered and coupled driving wheels on two axles, and no trailing wheels.

First built in the 1830s, locomotives with this wheel arrangement were known as "standard" or "Eight-Wheeler" type. In the first half of the 19th century, almost every major railroad in North America owned and operated locomotives of this type, and many rebuilt their 4-2-0 and 2-4-0 locomotives as 4-4-0s.

In April 1872, Railroad Gazette used "American" as the name of the type. The type subsequently also became popular in the United Kingdom, where large numbers were produced.

The vast majority of 4-4-0 locomotives had tenders, though some tank locomotives (designated 4-4-0T) were built.
Deepak Wadhwa
Deepak Wadhwa (born 26 October 1987) is an Indian actor. He has performed many roles in various Hindi television shows, like Dhoondh Legi Manzil Humein, Kaali- Ek Punar Avtaar, Ishq Kills, Qubool Hai, Tamanna, Code Red and Haasil. As of July 2017, he has done his most recent role in Yeh Hai Mohabbatein. He has also appeared in a cameo in Calendar Girls. He is known for playing lead role of Sanjay in Star Plus sports-drama Meri Tamanna and Rahaat in Zee TV's Qubool Hai.

Code Red (Indian TV series)
Code Red (also known as Code Red Chakravyuh, Code Red Umeed, Code Red Awaaz, Code Red Talaash) is an Indian television crime show, which had a premiere on Colors TV on 19 January 2015. The show was hosted by Sakshi Tanwar.

Code Red Talaash is an Indian supernatural television sub-series of Code Red, which airs on Colors TV. The series premiered on 22 April 2015 on Wednesday and airs Wednesday thorough Friday nights for an hour. The series showcases real life stories in view of super common forces. The sub-series shows some of the most popular paranormal occurrences in India and narrates the untold story behind every supernatural incidence. The show is hosted by Anita Hassanandani and Shaleen Malhotra.

The series is a part of Code Red that airs on Colors TV and explores the myths behind various haunted places in India.
Shani Taragin
Rabbanit Shani Taragin (Hebrew: שני טרגין; born 1974) is a noted American–Israeli Modern Orthodox and Religious Zionist author, educator, and lecturer specializing in Tanakh and Talmud. She is the Educational Director for World Mizrachi-Religious Zionists of America and of Matan Eshkolot at Matan Women's Institute for Torah Studies. She is also a Yoetzet Halacha (halachic advisor).

Yoetzet halacha
Yoetzet Halacha (Hebrew: יועצת הלכה, plural Yoatzot Halacha, יועצות הלכה; lit. “female advisor in Jewish law”) is an advisory role within Orthodox Judaism in which a woman is trained and certified to counsel other women on questions relating to Taharat HaMishpacha (Jewish family purity) and associated laws and women’s health issues. The position was established to provide halachic guidance in areas that many women find sensitive and prefer to discuss with another woman .
Gua Musang District
Gua Musang (Kelantanese: Guo Musey) is a town, district and parliamentary constituency in southern Kelantan, Malaysia. It is the largest district in Kelantan. Gua Musang is administered by the Gua Musang District Council. Gua Musang district is bordered by the state of Pahang to the south, Terengganu to the east, Perak to the west and the Kelantanese districts of Kuala Krai and Jeli to the north. It is a small railway town about 140 km south of state capital Kota Bharu. Gua Musang is represented by Mohd Azizi Abu Naim in the Dewan Rakyat. The town lies on the KTM East Coast Line, from Tumpat, near the border with Thailand, to Gemas, Negeri Sembilan. Gua Musang also famous because of Malay horror film Pontianak Dari Gua Musang.

The Lojing Autonomous Sub-District (Jajahan Kecil Lojing) is in the western part of Gua Musang constituency.

Jeli District
Jeli is a district and a parliamentary constituency in western Kelantan, Malaysia. As of 2010, the district's population is estimated to be 42,150. Jeli is administered by the Jeli District Council. Jeli is bordered by Perak's Hulu Perak District to the west, the Thai district of Waeng to the north, Tanah Merah District to the northeast and Kuala Krai District to the southeast.

Most people in Jeli work as rubber tappers. The rubber plantations which belong to the local people also attract people from outside to come and work. Commonly families own a small plantation of 6 acres (24,000 m2) up to 50 acres (200,000 m2) in size. The history of Jeli began when the government encouraged the people around Kelantan to start a great area of agriculture.  This process began with a period of land clearing, or logging.
Mission Albany
Mission Albany was a parachute combat assault at night by the U.S. 101st Airborne Division on June 6, 1944, part of the American airborne landings in Normandy during World War II. It was the opening step of Operation Neptune, the assault portion of the Allied invasion of Normandy, Operation Overlord. Five hours ahead of the D-Day landings, 6,928 paratroopers jumped from 443 C-47 Skytrain troop-carrier planes into the southeast corner of France's Cotentin Peninsula. The troops were meant to land in an area of roughly 15 square miles (39 km2), but were scattered by bad weather and German ground fire over an area twice as large, with four sticks dropped as far as 20 miles (32 km) away.

The division took most of its objectives on D-Day, but required four days to consolidate its scattered units and complete its mission of securing the left flank and rear of the U.S. VII Corps, reinforced by 2,300 glider infantry troops who landed by sea.

Cotentin Peninsula
The Cotentin Peninsula (US: /ˌkoʊtɒ̃ˈtæ̃/, French: [kɔtɑ̃tɛ̃]; Norman: Cotentîn [kotɑ̃ˈtẽ] ⓘ), also known as the Cherbourg Peninsula, is a peninsula in Normandy that forms part of the northwest coast of France.  It extends north-westward into the English Channel, towards Great Britain. To its west lie the Gulf of Saint-Malo and the Channel Islands, and to the southwest lies the peninsula of Brittany.

The peninsula lies wholly within the department of Manche, in the region of Normandy.
Myelination
Myelination, or myelinogenesis, is the formation and development of myelin sheaths in the nervous system, typically initiated in late prenatal neurodevelopment and continuing throughout postnatal development. The term myelinogenesis is also sometimes used to differentiate the very early stages of embryonic myelination.

Myelin is formed by oligodendrocytes in the central nervous system and Schwann cells in the peripheral nervous system.  Myelination continues throughout the lifespan to support learning and memory via neural circuit plasticity as well as remyelination following injury. Successful myelination of axons increases action potential speed by enabling saltatory conduction, which is essential for timely signal conduction between spatially separate brain regions, as well as provides metabolic support to neurons.

Remyelination
Remyelination is the process of propagating oligodendrocyte precursor cells to form oligodendrocytes to create new myelin sheaths on demyelinated axons in the Central nervous system (CNS). This is a process naturally regulated in the body and tends to be very efficient in a healthy CNS.
The process creates a thinner myelin sheath than normal, but it helps to protect the axon from further damage, from overall degeneration, and proves to increase conductance once again. The processes underlying remyelination are under investigation in the hope of finding treatments for demyelinating diseases, such as multiple sclerosis.

As of 2022 the status of possible remyelination acceleration is of trials only, with side effects of possible drugs one limiting issue.
Hump Back
Hump Back (Japanese: ハンプバック, Hepburn: Hampubakku) is a Japanese all-female  rock band formed in Higashiōsaka, Osaka in 2009. Lead vocalist and guitarist Momoko Hayashi has been the only constant member, with bassist Pika and drummer Misaki completing the lineup since 2016.

Chatmonchy
Chatmonchy (チャットモンチー, chattomonchī) was a three-piece all-female rock band which consisted of Eriko Hashimoto (guitar, vocals), Akiko Fukuoka (bass, chorus), and formerly Kumiko Takahashi (drums, chorus) who are from Tokushima Prefecture on the island of Shikoku, Japan.

From 2005, they were signed to Sony Music Japan's Ki/oon Records record label. In November 2017, the band announced that they were disbanding.

The band had their final single-act concert on July 4, 2018, at the Nippon Budokan, and held their last "Konason Fest" on July 21 and 22.
Opera Comique
The Opera Comique was a 19th-century theatre constructed in Westminster, London, located between Wych Street, Holywell Street and the Strand. It opened in 1870 and was demolished in 1902, to make way for the construction of the Aldwych and Kingsway.

The theatre was built cheaply as a speculative venture, and was known as one of the "rickety twins" along with the adjacent Globe Theatre. Numerous managements presented plays in English, French and German, and the house was also used for extravaganzas and English versions of French opéras bouffes. It is best remembered as the theatre where several early Gilbert and Sullivan operas had their first runs, between 1877 and 1881.

A4200 road
The A4200 is a major thoroughfare in central London. It runs between the A4 at Aldwych, to the A400 Hampstead Road/Camden High Street, at Mornington Crescent tube station, via Holborn, Bloomsbury, Euston and Somers Town.
Fifth Extraordinary Session of the Islamic Summit Conference
The Fifth Extraordinary Session of the Islamic Summit Conference was held from 6–7 March 2016 in Jakarta, Indonesia. The heads of the 57 member countries of the Organization of Islamic Cooperation (OIC), including notable figures such as the Vice President of Indonesia, Muhammad Jusuf Kalla, and Sudan’s President Omar al-Bashir participated in the summit. The conference aimed to address various pressing issues affecting the Muslim world, including internal and external conflicts in the Middle East, radicalism, and current terrorism. The summit also reaffirmed support for Palestine and called for an international ban on products from Israeli settlements in the West Bank.

Jusuf Kalla
Muhammad Jusuf Kalla (listenⓘ; born 15 May 1942), commonly referred to by his initials JK, is an Indonesian politician and businessman who served as the 10th and 12th Vice President of Indonesia, the only Vice President in Indonesian history to serve two non-consecutive terms in office (2004–2009 and 2014–2019). He was unsuccessful as Golkar's presidential nominee in the 2009 presidential election. Before Kalla declared himself as the running mate for Joko Widodo in the 2014 presidential election, a 2012 poll placed his popularity among likely voters in the top three contenders for the presidency and ahead of his own party's nominee Aburizal Bakrie.

Since 2009 Kalla serves as the chairman of the Indonesian Red Cross Society.
Venta (river)
The Venta (Latvian pronunciation [ˈvænta], Lithuanian [venˈta] ⓘ, German: Windau, Polish: Windawa, Livonian Vǟnta joug) is a river in north-western Lithuania and western Latvia. Its source is near Kuršėnai in the Lithuanian Šiauliai County. It flows into the Baltic Sea at Ventspils in Latvia.

On the territory of Lithuania along the Venta are cities Užventis, Kuršėnai, Venta, Viekšniai and Mažeikiai. In Latvia, the cities of Skrunda, Kuldīga, Piltene and Ventspils are located on the Venta river. Venta Rapid, the widest waterfall in Europe, is on Venta river in Kuldīga, Latvia.

Šiauliai County
Šiauliai County (Lithuanian: Šiaulių apskritis) is one of ten counties in Lithuania. It is in the north of the country, and its capital is Šiauliai. On 1 July 2010, the county administration was abolished, and since that date, Šiauliai County remains as a territorial and statistical unit. It borders Latvia.
Layn R. Phillips
Layn Raymond Phillips (born January 2, 1952) is a former United States district judge of the United States District Court for the Western District of Oklahoma. He conducts alternative dispute resolution, including mediation and arbitration.

United States District Court for the Western District of Oklahoma
The United States District Court for the Western District of Oklahoma (in case citations, W.D. Okla. or W.D. Ok.) is a federal court in the Tenth Circuit (except for patent claims and claims against the U.S. government under the Tucker Act, which are appealed to the Federal Circuit).

The District was established on June 16, 1906, and became operational on November 16, 1907, with Oklahoma achieving statehood.
WWFM
WWFM (89.1 FM, "The Classical Network") is a non-commercial, listener-supported radio station owned and operated by Mercer County Community College (MCCC). It is licensed to Trenton, New Jersey, and its transmitter tower is located on the campus of MCCC in West Windsor Township.

WWFM is the flagship station of "The Classical Network". Programming is also heard on WWNJ (91.1 FM) in Toms River Township, WWCJ (89.1 FM) in Cape May, and WWPJ (89.5 FM) in Pen Argyl, Pennsylvania. In the Philadelphia area, "The Classical Network" is heard on the second HD Radio subchannel of WYPA (89.5 FM) in Cherry Hill, New Jersey. In the New York City area, "The Classical Network" is heard on the second HD subchannel of WKCR-FM (89.9 FM). Programming is also heard on several FM translators in New Jersey, Pennsylvania and Colorado.

Cherry Hill, New Jersey
Cherry Hill is a township within Camden County, in the U.S. state of New Jersey. As a suburb of Philadelphia, the township is part of the South Jersey and Delaware Valley regions. Cherry Hill Township grew during the mid-20th century suburbanization, becoming one of the Delaware Valley's main commercial centers, including the Cherry Hill Mall. As of the 2020 United States census, the township's population was 74,553.
William H. Johnson (artist)
William Henry Johnson (March 18, 1901 – April 13, 1970) was an American painter. Born in Florence, South Carolina, he became a student at the National Academy of Design in New York City, working with Charles Webster Hawthorne. He later lived and worked in France, where he was exposed to modernism. After Johnson married Danish textile artist Holcha Krake, the couple lived for some time in Scandinavia. There he was influenced by the strong folk art tradition. The couple moved to the United States in 1938. Johnson eventually found work as a teacher at the Harlem Community Art Center, through the Federal Art Project.

Johnson's style evolved from realism to expressionism to a powerful folk style, for which he is best known. A substantial collection of his paintings, watercolors, and prints is held by the Smithsonian American Art Museum, which has organized and circulated major exhibitions of his works.

Florence, South Carolina
Florence /ˈflɒrəns/ is a city in and the county seat of Florence County, South Carolina, United States. It lies at the intersection of Interstates 20 and 95 and is the eastern terminus of the former. It is the primary city within the Florence metropolitan area. The area forms the core of the historical Pee Dee region of South Carolina, which includes the eight counties of northeastern South Carolina, along with sections of southeastern North Carolina. As of the 2020 census, the population of the city was 39,899, making it the 10th-most populous city in the state.

Florence is one of the major cities in South Carolina. In 1965, Florence was named an All-American City, presented by the National Civic League. The city was founded as a railroad hub and became the junction of three major railroad systems, including the Wilmington and Manchester, the Northeastern, and the Cheraw and Darlington.
Cheer Up (song)
"Cheer Up" (stylized in all caps) is a song recorded by South Korean girl group Twice. It was released by JYP Entertainment on April 25, 2016, as the lead single from their second extended play Page Two. It was written and composed by Sam Lewis and Black Eyed Pilseung respectively.

A major commercial success, the song topped the Gaon Digital Chart and was the best-performing single of 2016 in South Korea. It also won several awards including Song of the Year in two major music awards shows, Melon Music Awards and Mnet Asian Music Awards. The song's "shy shy shy" line became a viral meme and was imitated by many celebrities.

JYP Entertainment
JYP Entertainment Corporation (Korean: JYP 엔터테인먼트) is a South Korean multinational entertainment and record label conglomerate founded in 1997 by J.Y. Park. Operating as a record label, talent agency, music production company, event management company, concert production company and music publishing house, it is one of the largest entertainment companies in South Korea. The company also operates subsidiary ventures and divisions internationally.
FC Santa Coloma
FC Santa Coloma is an Andorran professional football club based in Santa Coloma, parish of Andorra la Vella, that competes in the Primera Divisió. It is the most successful team in both Primera Divisió and Copa Constitució, having won both titles thirteen and ten times respectively.

Copa Constitució
The Copa Constitució or Andorran Cup, also known is Copa Constitució Valira Seguretat for sponsorship reasons, is the national football cup competition in Andorra organized by the Andorran Football Federation.  The Cup annual tournament began in 1990.  Since the 1994–95 season, the tournament has been affiliated with FIFA and UEFA.