hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Catecholamines up
Catecholamines up (Catsup) is a dopamine regulatory membrane protein that functions as a zinc ion transmembrane transporter (orthologous to ZIP7), and a negative regulator of rate-limiting enzymes involved in dopamine synthesis and transport: Tyrosine hydroxylase (TH), GTP Cyclohydrolase I (GTPCH), and Vesicular Monoamine Transporter (VMAT) in Drosophila melanogaster.

Catsup plays a significant role in zinc ion transmembrane transport, and the mutations in Catsup gene can lead to abnormal accumulation of membrane proteins, such as Notch, decreased  Notch signalling, increase in levels of apoptosis, and induce of ER stress response. Additionally, Catsup plays an important role in regulation of dopamine synthesis, and the mutations in Catsup gene can lead to hyperactivity of Catsup-regulated enzymes TH, GTPCH, and VMAT, as well as to increases in dopamine (DA) and tetrahydrobiopterin (BH4) levels.

Vesicular monoamine transporter
The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons. It transports monoamine neurotransmitters – such as dopamine, serotonin, norepinephrine, epinephrine, and histamine – into the vesicles, which release the neurotransmitters into synapses, as chemical messages to postsynaptic neurons. VMATs utilize a proton gradient generated by V-ATPases in vesicle membranes to power monoamine import.

Pharmaceutical drugs that target VMATs have possible applications for many conditions, leading to a plethora of biological research, including hypertension, drug addiction, psychiatric disorders, Parkinson's disease, and other neurological disorders. Many drugs that target VMATs act as inhibitors and alter the kinetics of the protein. Much research regarding the effects of altered VMATs on biological systems is still ongoing.
Jnana Deepa, Institute of Philosophy and Theology
Jnana Deepa (JD), Institute for Philosophy and  Theology is located at Pune, India. It is the academic component of Papal Seminary,  Founded by the Pope Leo XIII with the motto “Filii tui India administri tibi salutis” in Kandy (Sri Lanka) in 1893, it was transferred to Pune (India) in 1955. Catering primarily to the formation of diocesan priests but open to  Catholic faithful and other religious orders, especially candidates to the Catholic priesthood it is entrusted by the Holy See to the Society of Jesus for training future Catholic leaders.

Kandy
Kandy (Sinhala: මහනුවර, romanised: Mahanuwara [mahanuʋərə] ⓘ; Tamil: கண்டி, romanised: Kaṇṭi [ˈkaɳɖi] ⓘ) is a major city located in the Central Province of Sri Lanka. It was the last capital of the Sinhalese monarchy from 1469 to 1818, under the Kingdom of Kandy. The city is situated in the midst of hills in the Kandy plateau. Kandy is the administrative  capital of the Central Province, and considered as the cultural capital of Sri Lanka, due to its architectural heritage. Kandy is the home of the Temple of the Tooth Relic (Sri Dalada Maligawa), one of the most important places of the Buddhist world. It was declared a World Heritage Site by UNESCO in 1988. Historically the local Buddhist rulers resisted Portuguese, Dutch, and British colonial expansion and occupation.
Versus (9ice album)
Versus is the fifth studio album by Nigerian singer 9ice. It was released on 7 December 2011 by Alapomeji Ancestral Records in conjunction with Bashorun Gaa. The album features a blend of Afrobeats and hip hop. The album was titled Versus because it includes many guest artists, with 9ice framing the collaborations as lyrical face-offs rather than standard features. The artists featured on the album consist of 2Face Idibia, Banky W., Duncan Mighty, Seriki, Mode 9, V.I.P, Tiwa Savage, Wizkid, Dagrin, M.I, Ajayi Brovas, Kwaw Kese, Timaya, Kwam 1, and Wizboyy. Versus's production was handled by ID Cabasa, Puffy Tee, Tee-Y Mix, Cheepho, Spellz, Duncan Mighty, E.L, and D'Tunes. The fifth track off the album, "Iya Alariya", was supposed to feature veteran musician King Sunny Adé, but the label failed to make time to get Adé and 9ice in the studio. Versus was nominated for Best R&B/Pop Album at The Headies 2012.

K1 De Ultimate
Wasiu Omogbolahan Olasunkanmi Adewale Ayinde Marshallistenⓘ MON (born 3 March 1957), known professionally as K1 De Ultimate, is a Nigerian Fuji musician. He popularised a brand of the genre based on the work of its creator, Ayinde Barrister, known as "Talazo Fuji".
Gianluca Havern
Gianluca Havern (born 24 September 1988) is an English retired footballer who played as a defender.

In his playing career, Havern had played for Stockport County, Radcliffe Borough, Ashton United, Mansfield Town and Hyde.

Radcliffe F.C.
Radcliffe Football Club (formerly Radcliffe Borough) is an English football club based in Radcliffe, Greater Manchester, where they play their home games at Stainton Park. The club was formed on 24 May 1949 and currently plays in the National League North, the sixth tier of the English football league system, after winning the 2023–24 Northern Premier League Premier Division title. Radcliffe won the Northern Premier League First Division in 1996–97, reached the first round of the FA Cup for the only time in its history in 2000, and won league playoffs in 2003 and 2019. The club changed its name to Radcliffe Football Club for the 2018–19 season.
New South Wales 45 (later 71) class locomotive
The 45 class (later the 71 class) is a one off mainline electric locomotive built in-house in 1952 by the New South Wales Department of Railways' Chullora Railway Workshops. With only a single locomotive in the class, 4501 was renumbered 7100 in October 1961, which freed up the number range for the 45-class diesel locomotives.

Chullora Railway Workshops
Chullora Railway Workshops were a major workshops for the repair and heavy maintenance of locomotives and rolling stock for the New South Wales Government Railways.

It was built on site at Chullora over 485 acres adjoining the main Sydney marshalling yards at Enfield. The decision to build a new workshop was made because of the inadequacy of the existing facilities at Eveleigh Railway Workshops and the decision to electrify the Sydney metropolitan network.

The master plan envisaged it would cover all aspects of railway operation with separate facilities for a locomotive workshop, carriage workshop, wagon repair depot, electric repair shop, signal engineers branch, general railway store, water supply and existing lines branch.
Jack Gordon (actor)
John Gordon (born 27 June 1985) is an English actor. He is best known for roles such as Sean in Elaine Constantine's Northern Soul, Ronnie Biggs in the BBC One TV-series The Great Train Robbery (2013 TV series) and Peter Foley in The Crimson Field. On the stage, he gained acclaim for his role as "man" in Philip Ridley's Tender Napalm and Giovanni in Cheek by Jowl's 'Tis Pity She's a Whore.

Tender Napalm
Tender Napalm is a 2011 play by Philip Ridley. Ridley's eighth stage play for adults, it premiered at London's Southwark Playhouse on 19 April 2011.

The original production was directed by David Mercatali, who previously directed the professional revival of Ridley's 2004 play Moonfleece in 2010. Since then Mercatali has collaborated with Ridley a number of times in directing the premiere productions for the majority of Ridley's new stage plays.

The production starred Vinette Robinson as Woman and Jack Gordon as Man, who had previously played a minor role in the 2009 horror film Heartless which was written and directed by Ridley.
2024 Austin mayoral election
The 2024 Austin mayoral election was held on November 5, 2024, to elect the next mayor of Austin, Texas. The election was nonpartisan; the candidates' party affiliations did not appear on the ballot. Incumbent mayor Kirk Watson was running for re-election, after returning to the position of mayor following the 2022 election. On November 15, over a week after election day, Watson was declared the apparent winner of the race after securing 50.0041% of the vote. In the final tally, Watson was a mere 13 votes over the cutoff to avoid a runoff with Carmen Llanes Pulido.

Due to the passage of Prop D in 2021, this is the first Austin mayoral election to coincide with a presidential election.

Mayor of Austin
The mayor of Austin is the official head of the city of Austin in the U.S. state of Texas. The office was established in 1840 after Austin incorporated as a city in 1839. The mayor of Austin is elected to a four-year term and limited to serving no more than two terms.

Kirk Watson took office as mayor on January 6, 2023, for a third term and was re-elected to a fourth term in 2024, having served as mayor from 1997 to 2001.
Anthology 2: Classic Hits 1967–1985 (Recorded Live)
Anthology 2: Classic Hits 1967–1985 (Recorded Live) is a compilation album by Australian singer John Farnham. The album was released in Australia on 29 September 1997, and is the second of a three disc anthology set. The album features live recorded versions of Farnham's older hits, rare soundtrack songs, as well as covers of Australian band Cold Chisel’s "When the War Is Over" and The Beatles’ “Help!” as well as "And I Love Her". Many of the live recordings presented in this collection also appear on Farnham's 1991 live album Full House.

Help! (song)
"Help!" is a song by the English rock band the Beatles that served as the title song for the 1965 film and the band's accompanying soundtrack album. It was released as a single in July 1965, and was number one for three weeks in the United States and the United Kingdom. Credited to Lennon–McCartney, "Help!" was written by John Lennon with some assistance from Paul McCartney. During an interview with Playboy in 1980, Lennon recounted: "The whole Beatles thing was just beyond comprehension. I was subconsciously crying out for help".

The song was ranked at number 29 on Rolling Stone's 500 Greatest Songs of All Time in 2004 and 2010, and then was re-ranked at number 447 in the 2021 list. In 2008, the 1965 Capitol Records recording of "Help!" was inducted into the Grammy Hall of Fame.
Will Draper
Will Draper (born 14 January 2000) is a professional British triathlete from the Isle of Man. Before starting a career in triathlon, Draper competed as a cyclist where he represented the Isle of Man at the 2017 Commonwealth Youth Games in the Bahamas for cycling. Draper won the English Triathlon Championships in 2019 before making his triathlon professional debut in 2021.

Commonwealth Youth Games
The Commonwealth Youth Games (CYG) is an international multi-sport event organized by the Commonwealth Games Federation. The games were held in the years, mid-way between when the Commonwealth Games are held, until 2008. They continued to be held every four years, but in the year after the Commonwealth Games are held, from 2011 to 2015. Since 2017, they've been held in the year before the Commonwealth Games are held. The first edition was held in Edinburgh, Scotland from 10 to 14 August 2000. The age limitation of the athletes is from 14 to 18.
Alexander Luttrell (1705–1737)
Alexander Luttrell (10 May 1705 – 4 June 1737) of Dunster Castle, Somerset, was an English politician and land-owner who served as Member of Parliament for his family's pocket borough of Minehead from 1727 until his death. He was the last in the male line of the Luttrell family, which had owned Dunster Castle since 1376.

Rotten and pocket boroughs
A rotten or pocket borough, also known as a nomination borough or proprietorial borough, was a parliamentary borough or constituency in England, Great Britain, or the United Kingdom before the Reform Act of 1832 which had very few voters. They could be used by a patron to gain disproportionate influence within the House of Commons. The Reform Act of 1832 abolished the majority of these rotten and pocket boroughs.

The same terms were used for similar boroughs represented in the 18th-century Parliament of Ireland.
William B. Hanna
William Blythe Hanna (January 5, 1866 – November 20, 1930) was an American sportswriter. Starting his career The Kansas City Star in the late 1870s, Hanna moved to New York City in 1892 to join the staff of the New York Herald. He never actually left his new city of residence. Over the following decades, he variously worked for the New York Herald, the New York Press, The Sun, and finally for the Herald's successor newspaper, the New York Herald Tribune

The Kansas City Star
The Kansas City Star is a newspaper based in Kansas City, Missouri. Published since 1880, the paper is the recipient of eight Pulitzer Prizes.

The Star is most notable for its influence on the career of President Harry S. Truman and as the newspaper where a young Ernest Hemingway honed his writing style. The paper is the major newspaper of the Kansas City metropolitan area and has widespread circulation in western Missouri and eastern Kansas.
Gilles Dumas
Gilles Dumas is a French rugby league football coach and former player. He is the coach of French Elite One Championship club, Saint-Gaudens Bears and previously Toulouse Olympique. He previously coached the French national team while coaching Saint Gaudens in the Elite 1 Championship in the 1990s and 2000s. Dumas was a France national representative goal-kicking fullback, scrum- or stand-off half back in his playing days during the 1980s and 1990s.

Super XIII
Super XIII is the top level rugby league competition in France, sanctioned by the French Rugby League Federation. The season runs from September to April, which is in contrast to the majority of other major domestic rugby league competitions worldwide. The clubs play each other home and away then they enter into a play-off series culminating with a Grand Final. The competition was founded in 2002, as the Elite One Championship and renamed as Super XIII at the start of the 2024–2025 season. The competition is the continuation of the French Rugby League Championship, which began in 1934.
Élisabeth Lochen
Élisabeth Löchen is a French filmmaker, and co-creator of the L.C. Concept ("Löchen-Chedville Concept") the French predecessor of the Digital Theater System.

Löchen has a PhD in psychology and entered the music industry after pursuing her academic interests.

DTS, Inc.
DTS, Inc. (an initialism of its original name, Digital Theater Systems) is an American company that makes multichannel audio technologies for film and video. Based in Calabasas, California, the company introduced its DTS technology in 1993 as a competitor to Dolby Laboratories, incorporating DTS in the film Jurassic Park (1993). The DTS product is used in surround sound formats for both commercial/theatrical and consumer-grade applications. It was known as The Digital Experience until 1995. DTS licenses its technologies to consumer electronics manufacturers.

DTS, Inc. was acquired by Tessera Technologies Inc. in December 2016 and combined under the newly created Tessera Holding Corporation. The combined company was renamed to Xperi Corporation in February 2017.
Kandik
Kandik or Kazrig was one of the three Scythian brothers mentioned in the chronicle of Michael of Syria, the Jacobite Patriarch of Antioch. After leading their Iverian people as refugees away from the Turks as Pseudo-Avar khagans, Kazrig and his brothers Bolgaris and Bayan I  approached Sarosius to mediate for him with the Byzantine Empire in 557. They soon conquered the remnant of the Akatziri Hunno-Bulgars also known as Kutrigurs from the time of Ernak.

Bayan I
Bayan I reigned as the first khagan of the Avar Khaganate between 562 and 602.

As the Göktürk Empire expanded westwards on the Eurasian Steppe during the 6th century, peoples such as the  Avars (also known as the Pseudo-Avars, Obri, Abaroi and Varchonites) and the Bulgars migrated into Central and the Southeast Europe. Bayan I led the Avars (along with many Proto-Bulgarians) into Pannonia, where they established their khaganate from 568.
Tūrangawaewae
Tūrangawaewae (Māori: [tʉːɾaŋawaewae]) is a marae and a royal residence in Ngāruawāhia, Waikato, New Zealand. It is the official residence of the Māori monarch and the administrative headquarters of the Kīngitanga movement. Of its numerous buildings, the two principal ones are the Māhinārangi meeting house, and Tūrongo House, which is official residence of the queen or king.

Māhinārangi and Tūrongo are made of wood and are covered in complex Māori carvings (whakairo), painted burgundy and cream. Over the years, it has undergone renovations, in harmony with the original style, which represents a unique synthesis of classical Māori and Edwardian architecture. For its 2012 renovations, Tūrangawaewae was awarded the New Zealand Institute of Architects' Waikato-Bay of Plenty Regional Award in the Heritage Category.

New Zealand Institute of Architects
The New Zealand Institute of Architects (NZIA) (Māori: Te Kāhui Whaihanga) is a membership-based professional organisation that represents approximately 90 per cent of registered architects in New Zealand and supports and promotes architecture in New Zealand.

The organisation was founded in 1905 and is committed to supporting members by providing ongoing professional training and material and services that are essential to their work.

The Institute has eight branches throughout the country and is headed by a president who serves a two-year term. The day-to-day functions of the Institute are undertaken by an Auckland-based team led by a chief executive.
Maplewood Flats Conservation Area
The Maplewood Flats Conservation Area is a 126 hectare (310 acre) conservation area located in North Vancouver, British Columbia, Canada. The area is composed of a 96 hectare (237 acre) intertidal zone of mudflats and salt marsh, and a 30 hectare (74 acre) upland area. It is preserved by Port Metro Vancouver as one of their ecological land initiatives. The land is located approximately 2 km east of the Second Narrows Bridge along Burrard Inlet in North Vancouver.

Port of Vancouver
The Port of Vancouver is the largest port in Canada and the fourth largest in North America by tonnes of cargo, facilitating trade between Canada and more than 170 world economies. The port is managed by the Vancouver Fraser Port Authority, which was created in 2008 as an amalgamation of the former Port of Vancouver, the North Fraser Port Authority, and the Fraser River Port Authority. It is the principal authority for shipping and port-related land and sea use in the Metro Vancouver region.
Penrose–Hawking singularity theorems
The Penrose–Hawking singularity theorems (after Roger Penrose and Stephen Hawking) are a set of results in general relativity that attempt to answer the question of when gravitation produces singularities. The Penrose singularity theorem is a theorem in semi-Riemannian geometry and its general relativistic interpretation predicts a gravitational singularity in black hole formation. The Hawking singularity theorem is based on the Penrose theorem and it is interpreted as a gravitational singularity in the Big Bang situation. Penrose shared half of the Nobel Prize in Physics in 2020 "for the discovery that black hole formation is a robust prediction of the general theory of relativity".

Reissner–Nordström metric
In physics and astronomy, the Reissner–Nordström metric is a static solution to the Einstein–Maxwell field equations that corresponds to the gravitational field of a charged, non-rotating, spherically symmetric body of mass . The analogous solution for a charged, rotating body is given by the Kerr–Newman metric.

The metric was discovered between 1916 and 1921 by Hans Reissner, Hermann Weyl, Gunnar Nordström and George Barker Jeffery independently.
2020–21 Marsh One-Day Cup
The 2021 Marsh One-Day Cup was the 52nd season of the official List A domestic cricket competition being played in Australia. On 26 June 2020, Cricket Australia confirmed all the squads for the 2020–21 domestic cricket season. Western Australia were the defending champions.

On 16 December 2020, Cricket Australia confirmed the schedule of the tournament, with the final scheduled to be played on 30 April 2021, the latest finish to a domestic cricket season in Australia. On 10 February 2021, Cricket Australia announced the reduction of the tournament from 22 to 16 matches due to concerns over bubble fatigue, which resulted in a full schedule change.

New South Wales won the tournament, after they beat Western Australia by 102 runs in the final.

One-Day Cup (Australia)
The One-Day Cup, for which the prize was renamed the Dean Jones Trophy from the 2024–25 season, is an Australian domestic List A 50-over limited-overs cricket tournament. It has had many different names, formats and teams since the inaugural 1969-1970 season. Initially a knockout cup, the competition now features a single round-robin followed by a finals series.

The tournament is contested between teams representing the six states of Australia, who also compete in the first-class Sheffield Shield. Three other teams have also played in the tournament for short periods: New Zealand's national team competed from 1969–70 until the 1974–75, Australian Capital Territory participated from 1997–98 until 1999–2000, and a select Cricket Australia XI took part as the seventh team for three seasons from 2015–16 until 2017–18. The current champions are South Australia.
Unchained (film)
Unchained is a 1955 prison film written, produced and directed by Hall Bartlett (the first film directed by Bartlett) and starring Elroy Hirsch, Barbara Hale, Chester Morris, Todd Duncan, and Johnny Johnston. Based on the non-fiction book Prisoners are People by Kenyon J. Scudder, it is most remembered for its theme song, "Unchained Melody".

Barbara Hale
Barbara Hale (April 18, 1922 – January 26, 2017) was an American actress who portrayed legal secretary Della Street in the dramatic television series Perry Mason (1957–1966), earning her a 1959 Emmy Award for Outstanding Supporting Actress in a Drama Series. She reprised the role in 30 Perry Mason made-for-television movies (1985–1995).
Here's My Plan
Here's My Plan (Korean: 목표가 생겼다) is a 2021 South Korean television series starring Kim Hwan-hee, Ryu Soo-young, Kim Do-hoon and Lee Young-jin. The screenplay won the award for outstanding work at the 2020 MBC Drama Screenplay Contest and was selected with the highest praise from judges. It aired on MBC TV from May 19–27, 2021.

Kim Hwan-hee
Kim Hwan-hee (Korean: 김환희; born August 25, 2002) is a South Korean actress. She began her career as a child actress in 2008, and has been active ever since. She has starred in television dramas such as Invincible Lee Pyung Kang (2009), Believe in Love (2010), My One and Only (2010), and You Are the Best! (2013), as well as the films Born to Sing (2013) and The Wailing (2016).
John Cryer
John Robert Cryer, Baron Cryer (born 11 April 1964), is a British politician. A member of the Labour Party, he was previously the Member of Parliament (MP) for Hornchurch from 1997 to 2005 and the MP for Leyton and Wanstead from 2010 to 2024. Cryer was Chair of the Parliamentary Labour Party from 2015 to 2024, and was a lord-in-waiting in the House of Lords from 2024 until 2025.

Parliamentary Labour Party
The Parliamentary Labour Party (PLP) is the parliamentary group of the Labour Party in the British House of Commons. The group comprises the Labour members of parliament as a collective body. Commentators on the British Constitution sometimes draw a distinction between the Labour Party (which was created outside Parliament and later achieved office) and the Conservative and Liberal parties (which began as parliamentary factions). The term Parliamentary Labour Party refers to the party in Parliament, whereas the term Labour Party refers to the entire Labour Party, the parliamentary element of which is the PLP.

A similar body for the Conservative Party is the 1922 Committee.

An organisation for former members, the PLP in exile, was established following the 2010 general election.