hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Calaspargase pegol
Calaspargase pegol, sold under the brand name Asparlas, is a medication for the treatment of acute lymphoblastic leukemia (ALL).  It is approved in the United States as a component of a multi-agent chemotherapeutic regimen for ALL in pediatric and young adult patients aged one month to 21 years.

Calaspargase pegol is an engineered protein consisting of the E. coli-derived enzyme L-asparaginase II conjugated with succinimidyl carbonate monomethoxypolyethylene glycol (pegol). The L-asparaginase portion hydrolyzes L-asparagine to L-aspartic acid depriving the tumor cell of the L-asparagine it needs for survival.  The conjugation with the pegol group increases the half-life of the drug making it longer acting.

The most common (incidence ≥ 10%) grade ≥ 3 adverse reactions are elevated transaminase, increased bilirubin, pancreatitis, and abnormal clotting studies.

Asparaginase
Asparaginase is an enzyme that is used as a medication and in food manufacturing. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL). It is given by injection into a vein, or muscle. A PEGylated version, pegaspargase, is also available. In food manufacturing it is used to decrease acrylamide.

Common side effects when used by injection include allergic reactions, pancreatitis, blood clotting problems, high blood sugar, kidney problems, and liver dysfunction. Use in pregnancy may harm the baby. As a food it is generally recognized as safe. Asparaginase works by breaking down the amino acid known as asparagine without which the cancer cells cannot make protein.

Asparaginase was approved for medical use in the United States in 1978. It is on the World Health Organization's List of Essential Medicines. It is often made from Escherichia coli (E. coli) or Erwinia chrysanthemi.
Kempston
Kempston is a town and civil parish in the Borough of Bedford, Bedfordshire, England, situated around 2 miles (3.2 km) south-west of Bedford town centre. It had a population of 19,330 in the 2011 census, and forms part of the wider Bedford built-up area. The River Great Ouse separates it from the Queen's Park area of Bedford.

Bedford
Bedford is a market town in Bedfordshire, England. At the 2021 Census, the population of its urban area was 167,446. Bedford is the county town of Bedfordshire and seat of the Borough of Bedford local government district.

Bedford was founded at a ford on the River Great Ouse and is thought to have been the burial place of King Offa of Mercia, who is remembered for building Offa's Dyke on the Welsh border. Bedford Castle was built by Henry I, although it was destroyed in 1224. Bedford was granted borough status in 1166 and has been represented in Parliament since 1265. It is known for its large population of Italian descent.
K-260 (Kansas highway)
K-260 is a 3.621-mile-long (5.827 km) east–west state highway through Moundridge in the U.S. State of Kansas. It connects at both ends to Interstate 135 (I-135) and U.S. Route 81 (US-81). The section of K-260 from Moundridge northward is signed north–south and the section from Moundridge westward is signed east–west. The route was first designated in 1966 when US-81 was realigned onto I-35W, now known as I-135.

Interstate 135
Interstate 135 (I-135) is an approximately 95.7-mile-long (154.0 km) auxiliary Interstate Highway in central and south-central Kansas, United States. I-135, which is signed as north–south, runs between I-35 and the Kansas Turnpike in Wichita north to I-70, U.S. Highway 40 (US-40), and US-81 in Salina. Except for the first 0.46 miles (0.74 km), I-135 overlaps US-81 its entire length. The route also runs through the cities of McPherson, Newton, and Park City.

The highway was designated as Interstate 35W (I-35W) until September 1976, when it was renumbered as I-135 to conform to new AASHTO policies that eliminated most suffixed Interstate Highways. It is currently the longest three-digit spur with an odd first digit in the Interstate System.
1929–30 NHL season
The 1929–30 NHL season was the 13th season of the National Hockey League. Ten teams played 44 games each. The Montreal Canadiens upset the heavily favoured Boston Bruins two games to none in the Stanley Cup Finals.

Newsy Lalonde
Édouard Cyrille "Newsy" Lalonde (October 31, 1887 – November 21, 1970) was a Canadian professional ice hockey forward in the National Hockey League (NHL) and a professional lacrosse player.  Lalonde is regarded as one of hockey's and lacrosse's greatest players of the first half of the 20th century and one of Canadian sport's most colourful characters. He played for the Montreal Canadiens – considered to be the original "Flying Frenchman" – in the National Hockey Association and the NHL. As player-coach, Lalonde led the Canadiens to their first Stanley Cup in 1916. His goal-scoring prowess in the 1919 Stanley Cup playoffs set three NHL records that remain unbroken over a century later. He also played for the WCHL's Saskatoon Sheiks.
2021 Oregon State Beavers football team
The 2021 Oregon State Beavers football team represented Oregon State University during the 2021 NCAA Division I FBS football season. They were led by fourth-year head coach Jonathan Smith. The team played their home games on campus at Reser Stadium in Corvallis, Oregon, as a member of the North Division of the Pac-12 Conference.

Defensive Coordinator Tim Tibesar's contract was terminated on November 7, the day after their 37–34 loss to Colorado.

Jonathan Smith (American football coach)
Jonathan Charles Smith (born January 18, 1979) is an American college football coach. He was most recently the head football coach at Michigan State University, serving from 2024 to 2025. He was previously the head football coach for six seasons, from 2018 to 2023, at his alma mater, Oregon State University. As a player, Smith was a four-year starter at quarterback for the Oregon State Beavers under head coaches Mike Riley and Dennis Erickson.
T. B. Shotts
Thomas Bolton Shotts (October 1, 1902 – May 7, 1950) was an American college football player and coach. He served as the head football coach at Jacksonville State University–then known as Jacksonville State Teachers College–from 1931 to 1937. He was a graduate of Auburn University, where he selected to the 1927 College Football All-Southern Team as a fullback.

Shotts died on May 7, 1950, at Eliza Coffee Memorial Hospital in Florence, Alabama, after a brief illness.

1927 College Football All-Southern Team
The 1927 College Football All-Southern Team consists of American football players selected to the College Football All-Southern Teams selected by various organizations in for the 1927 Southern Conference football season.
2014 Philadelphia Union season
The 2014 Philadelphia Union season was the club's fifth season of existence, competing in Major League Soccer, the top flight of American soccer. The club was initially managed by John Hackworth, in his third season (second full season) with the club. In June, Hackworth was fired from his role as head coach and assistant coach Jim Curtin was promoted on an interim basis. At the conclusion of the season, Curtin was officially made permanent head coach, making him the third head coach in the club's history. The 2014 season marked the first time the Union reached a competition finals, finishing runners-up in the 2014 U.S. Open Cup to Seattle Sounders FC.

Jim Curtin
Jim Curtin (born June 23, 1979) is an American professional soccer coach and former player who was most recently the head coach of the Philadelphia Union of Major League Soccer. He spent most of his playing career with the Chicago Fire.
Teen Titans: Earth One
Teen Titans: Earth One  is a series of graphic novels written by Jeff Lemire, penciled by Terry Dodson and inked by Rachel Dodson and Cam Smith. The novel is a modernized re-imagining of DC Comics' long-running Teen Titans comic book series as part of the company's Earth One imprint. Earth One's Teen Titans exists alongside other revamped DC characters in Earth One titles, including Superman: Earth One and Batman: Earth One, as well as other graphic novels.

Volume One was released on November 19, 2014, while Volume Two was released on August 10, 2016.

Superman: Earth One
Superman: Earth One is a series of graphic novels written by J. Michael Straczynski and illustrated by Shane Davis. The series is a modernized re-imagining of DC Comics' long-running Superman comic book franchise as the inaugural title of the company's Earth One imprint. Earth One's Superman exists with other revamped DC characters in Earth One titles, including Batman: Earth One and Wonder Woman: Earth One, as well as other graphic novels.

The first volume was published in the US in October 27, 2010 by DC Comics, and in the UK in 2011 by Titan Books. Superman: Earth One Volume Two was released on October 31, 2012. Superman: Earth One Volume Three was released on February 4, 2015, with Ardian Syaf illustrating the book instead of Davis.
LA Giltinis
The LA Giltinis were a Major League Rugby team based in Los Angeles, California, United States. The team was announced in 2020 and entered the league in the 2021 season as an expansion franchise. Owned by Adam Gilchrist and Loyals Rugby, the team was named for a yet-to-be-released drink, itself a portmanteau of "Gilchrist" and "martini". The Giltinis were based in El Segundo, California, and played at the Los Angeles Memorial Coliseum. Darren Coleman was their first head coach.

The club won the MLR Shield in their inaugural season, but were disqualified from the playoffs in 2022. The Giltinis and the Austin Gilgronis—another MLR team owned by Gilchrist—were removed from the league in October 2022.

2022 LA Giltinis season
The 2022 LA Giltinis season was the club's second and final season in Major League Rugby. Stephen Hoiles was the coach of the club for his first full year. Dave Dennis was the captain the club for the second consecutive year. The team finished the season second in the Western Conference standings, but was later disqualified from competing in the 2022 Major League Rugby playoffs due to violating league rules. The team was removed from the league for the 2023 season.

The Giltinis played their home matchups at Los Angeles Memorial Coliseum in Los Angeles, California.
Fruit Bowl
The Fruit Bowl was a post-season college football bowl game held in December at Kezar Stadium in San Francisco, California. The game was held three times, following the 1947–1949 seasons. The first two games featured college teams and the last involved club teams.

The games were important due to the inclusion of schools that are considered historically black colleges and universities (HBCUs) in both the 1947 and 1948 games. The 1947 game featured two such schools, Wilberforce and Prairie View  A&M. This was the first meeting of HBCUs in San Francisco. The 1948 game was the first inter-racial bowl game played in the United States—it featured Southern and San Francisco State.

1947 Prairie View A&M Panthers football team
The 1947 Prairie View A&M Panthers football team was an American football team that represented Prairie View A&M University in the Southwestern Athletic Conference (SWAC) during the 1947 college football season. In their third season under head coach Billy Nicks, the team compiled a 6–6 record, lost to Wilberforce State in the Fruit Bowl and to Texas Southern in the Prairie View Bowl, and was outscored by a total of 137 to 89. Prairie View ranked No. 17 among the nation's black college football teams according to the Pittsburgh Courier and its Dickinson Rating System.
James W. Rutherford
James W. Rutherford (April 23, 1925 – January 14, 2010) was a mayor of the City of Flint, Michigan serving as the first "strong" mayor elected under Flint's 1974 charter. Rutherford served for two terms. Rutherford was elected as a caretaker mayor after Mayor Stanley was recalled and an Emergency Financial Manager, Ed Kurtz, was appointed by the state.

Woodrow Stanley
Woodrow Stanley (June 12, 1950 – February 15, 2022) was an American Democratic Party politician. He was mayor of Flint, Michigan from 1991 until his recall in 2002, and was a member of the Michigan House of Representatives from District 34 from 2009 to 2014.
Roanoke Red Sox
The Roanoke Red Sox was a primary name of the minor league baseball teams based in Roanoke, Virginia. Between 1894 and 1953, Roanoke teams played as members of the Virginia League (1894–1896, 1906–1914, 1939–1942) and Piedmont League (1943–1953), winning five league championships and one pennant. Roanoke teams were a minor league affiliate of the Cleveland Indians in 1940 and Boston Red Sox from 1943 to 1953. Baseball Hall of Fame members Jack Chesbro (1896) and Heinie Manush (1943) played for Roanoke.

The Roanoke Red Sox preceded today's Class A level Salem Red Sox of the Carolina League.

Salem RidgeYaks
The Salem RidgeYaks are a Minor League Baseball affiliate of the Boston Red Sox of Major League Baseball (MLB), based in Salem, an independent city adjacent to Roanoke, Virginia. The team competes at the Single-A level in the Carolina League. Home games are played at Carilion Clinic Field at Salem Memorial Ballpark, a 6,300-seat facility opened in 1995.

The team first played in 1955, and then from 1957 to 1967, in the Appalachian League, initially at the now-defunct Class D level, and then at the Rookie level starting in 1963. From 1968 through 2020, the team competed in the Carolina League, initially Class A and then Class A-Advanced starting in 1990.

The team was known as the Salem Avalanche from 1995 through 2008, when it was affiliated with the Colorado Rockies (1995–2002) and Houston Astros (2003–2008). Prior to 1995, the franchise played under several other names and affiliations. In 2009, the team rebranded as the Salem Red Sox before adopting the RidgeYaks identity for 2026.
2005 Boston College Eagles football team
The 2005 Boston College Eagles football team represented Boston College during the 2005 NCAA Division I-A football season. Boston College was in their first year as a member of the Atlantic Coast Conference. The Eagles played their home games at Alumni Stadium in Chestnut Hill, Massachusetts, which has been their home stadium since 1957.

2005 NCAA Division I-A football season
The 2005 NCAA Division I-A football season was the highest level of college football competition in the United States organized by the National Collegiate Athletic Association (NCAA). The regular season began on September 1, 2005 and ended on December 3, 2005. The postseason concluded on January 4, 2006 with the Rose Bowl, which served as the season's BCS National Championship Game.

The USC Trojans and the Texas Longhorns finished the regular season as the only undefeated teams in Division I-A and consequently met in the Rose Bowl to play for the national title. Texas defeated USC largely due to the performance of quarterback Vince Young, who gained 467 yards of total offense and ran for three touchdowns. The Longhorns won their first national championship since 1970, and their first consensus national title since 1969.
Clem Loughlin
Clement Joseph Loughlin (November 15, 1892 – January 28, 1977) was a Canadian professional ice hockey defenceman who played hockey for the Victoria Cougars of the Pacific Coast Hockey Association and the Western Canada Hockey League, and the Detroit Cougars and Chicago Black Hawks of the National Hockey League. He was captain when the Victoria Cougars won the Stanley Cup in 1925. Clem Loughlin also coached the Chicago Black Hawks for three seasons starting with the 1934–35 season.

His younger brother Wilf Loughlin was also a professional hockey player and the two played together on the Victoria Aristocrats and Victoria Cougars teams in the PCHA.

In 1915, Loughlin won the Allan Cup as a member of the Winnipeg Monarchs.

1934–35 NHL season
The 1934–35 NHL season was the 18th season of the National Hockey League (NHL). Nine teams each played 48 games. The Ottawa Senators moved to St. Louis and became the St. Louis Eagles. The Montreal Maroons were the Stanley Cup winners as they swept the Toronto Maple Leafs in three games in the Stanley Cup Finals.
Tomas Sandström
Tomas Sandström (born September 4, 1964) is a Finnish-born Swedish former professional ice hockey right winger who played in the National Hockey League (NHL) from 1984 to 1999. Born in Finland, Sandström grew up in Fagersta, Sweden. A skilled power forward, he was effective when healthy but his career was marred by injuries due to his physical style of play.

He was a member of the 1997 Stanley Cup winning Detroit Red Wings team, and assisted on Darren McCarty's game-winning goal in the deciding Game 4.

1998–99 NHL season
The 1998–99 NHL season was the 82nd regular season of the National Hockey League. The league expanded to 27 teams with the addition of the Nashville Predators. The NHL also realigned to a strictly geographic six-division structure, with three per conference. The 1998–99 season marked the retirement of Wayne Gretzky, the NHL's all-time leading scorer, who played his final three NHL seasons with the New York Rangers. The Dallas Stars finished first in regular season play, and won the Stanley Cup championship over the Buffalo Sabres on a controversial triple-overtime goal by Brett Hull.
2024 NBL1 West season
The 2024 NBL1 West season was the fourth season of the NBL1 West and 35th overall in State Basketball League (SBL) / NBL1 West history. The regular season began on Thursday 28 March and ended on Saturday 20 July. The finals began on Friday 26 July and concluded with both the women's grand final and the men's grand final on Saturday 10 August.

The 2024 NBL1 season concluded with the third annual NBL1 National Finals being held at UniSC Arena and Caloundra Indoor Stadium on the Sunshine Coast.

Stephanie Gorman
Stephanie Gorman (born 18 April 2000) is an Australian professional basketball player for the Perth Lynx of the Women's National Basketball League (WNBL). She is also contracted with the Cockburn Cougars of the NBL1 West. She played college basketball for Utah State and San Diego. In 2023, she debuted for the Perth Lynx in the WNBL. With the Cockburn Cougars, she helped the team win the 2023 NBL1 West championship while earning grand final MVP honours. In 2025, she won her second championship with the Cougars.
2009 Akron Zips football team
The 2009 Akron Zips football team represented the University of Akron in the 2009 NCAA Division I FBS football season.  Akron competed as a member of the Mid-American Conference (MAC) East Division.  The team was coached by J. D. Brookhart and played their homes game at InfoCision Stadium.

2009 NCAA Division I FBS football season
The 2009 NCAA Division I FBS football season was the highest level of college football competition in the United States organized by the National Collegiate Athletic Association (NCAA).

The regular season began on September 3, 2009, and ended on December 12, 2009. The postseason concluded on January 7, 2010, with the BCS National Championship Game in Pasadena, California, where the Alabama Crimson Tide defeated the Texas Longhorns by the score of 37–21.

For the first time in the history of the Heisman Trophy, the annual award for the most outstanding player in college football, two previous Heisman winners played in the same season—2008 winner Sam Bradford of Oklahoma and 2007 winner Tim Tebow of Florida. For the first time since 1946, the top three vote-getters from the previous season all returned: Bradford, Colt McCoy of Texas, and Tebow, in that order.  Six teams finished the regular season undefeated; a record for the BCS era.
North Yorkshire (district)
North Yorkshire (legally, the County of North Yorkshire) is a non-metropolitan county and unitary authority area in the ceremonial county of North Yorkshire, England. It covers the majority of the North York Moors, the Vale of Mowbray and Vale of York, and the Yorkshire Dales. It does not include the north-east of the ceremonial county or the unitary authority area of York. The largest settlement is Harrogate, and the administrative centre is Northallerton. North Yorkshire is the largest local government area in England, with an area of 3,103 square miles (8,037 km2).

City of York
The City of York is a unitary authority area with city status in the ceremonial county of North Yorkshire, England.

The district's main settlement is York, and its coverage extends to the town of Haxby and the villages of Earswick, Upper Poppleton, Nether Poppleton, Copmanthorpe, Bishopthorpe, Dunnington, Stockton on the Forest, Rufforth, Askham Bryan and Askham Richard, among other villages and hamlets. The district had a population of 202,800 in the 2021 Census The City of York is administered by the City of York Council based in The Guildhall.
1988–89 WHL season
The 1988–89 WHL season was the 23rd season of the Western Hockey League (WHL), featuring fourteen teams and a 72-game regular season. Less than three years after the 1986 team bus crash that killed four players, the Swift Current Broncos put together the best season in the club's history. The Broncos won their first Scotty Munro Memorial Trophy for the best regular season record, and in the playoffs defeated the Portland Winter Hawks to win their first President's Cup as league champions—the Broncos went undefeated throughout the playoffs. This earned the Broncos a berth in the 1989 Memorial Cup tournament, which was hosted in Saskatoon. At the tournament, the Broncos defeated the host Saskatoon Blades to win the Memorial Cup title.

This was the first season for the Tri-City Americans after the New Westminster Bruins relocated to Kennewick, Washington prior to the season. The Americans became the fourth WHL club based in the United States.

Swift Current Broncos
The Swift Current Broncos are a Canadian major junior ice hockey team based in Swift Current, Saskatchewan. Founded in 1967, the Broncos relocated to Lethbridge, Alberta in 1974, and were known as the Lethbridge Broncos, before returning to Swift Current in 1986. The team plays in the East Division of the Western Hockey League's Eastern Conference, and hosts games at Innovation Credit Union iPlex. Swift Current is the smallest city with a team in the WHL, and the second smallest across the entire Canadian Hockey League. The Broncos are three-time WHL playoff champions, and won the 1989 Memorial Cup. Before any of their championships, the Broncos were known for a 1986 team bus crash that resulted in the deaths of four players.
Rat trick
The rat trick was a celebration performed by fans of the Florida Panthers of the National Hockey League (NHL) during their 1995–96 season, in which plastic rats were thrown onto the ice to celebrate goals. The term, a play on hat trick, was coined by Panthers goaltender John Vanbiesbrouck after teammate Scott Mellanby killed a rat in the locker room prior to the team's home opener with his stick, then scored two goals with the same stick. By the time the Panthers reached the 1996 playoffs, thousands of rats hit the ice after every Panthers goal, resulting in an off-season rule change by the NHL that allowed for referees to penalize the home team if fans disrupted the game by throwing objects onto the ice.

1995–96 Florida Panthers season
The 1995–96 Florida Panthers season was the third season of the franchise that was established in 1993. In their third season in the National Hockey League (NHL), the Panthers qualified for the Stanley Cup playoffs for the first time in franchise history, becoming the Eastern Conference champions. They then played in the 1996 Stanley Cup Final, where Florida lost to the Colorado Avalanche in four games. The Panthers would not win another playoff series until the 2021–22 season. This season was tied for their most successful season ever (also 2022–23) until the 2023–24 season, when the Panthers won the Stanley Cup Final.