hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Fosigotifator
Fosigotifator is an experimental small-molecule related to ISRIB that activates the eukaryotic initiation factor eIF2; it was licensed by Calico from University of California, San Francisco and partnered with AbbVie. Abbvie and Calico ran clinical trials to determine if the drug can treat amyotrophic lateral sclerosis (ALS) and major depressive disorder. A formulation of fosigotifator, as its monosodium phosphate salt mixed with tromethamine, is known as ABBV-CLS-7262. Fosigotifator has been patented by AbbVie and Calico as a prodrug for modulation of the integrated stress response pathway.

In January 2025 Abbvie and Calico announced that the drug had failed a Phase 2/3 trial in ALS; in November 2025 Abbvie ended its partnership with Calico.

Calico (company)
Calico Life Sciences LLC is an American biotechnology company with a focus on the biology of aging, attempting to devise interventions that may enable people to lead longer and healthier lives. It is a subsidiary of Alphabet Inc.
Tungsten(VI) oxytetrabromide
Tungsten(VI) oxytetrabromide is the inorganic compound with the formula WOBr4. This a red-brown, hygroscopic solid sublimes at elevated temperatures. It forms adducts with Lewis bases. The solid consists of weakly associated square pyramidal monomers. The related tungsten(VI) oxytetrachloride has been more heavily studied. The compound is usually classified as an oxyhalide.

It can be produced by the reaction of tungsten hexabromide and tungsten trioxide:

2 WBr6 + WO3 → 3 WOBr4

Tungsten hexabromide
Tungsten hexabromide, also known as tungsten(VI) bromide, is a chemical compound of tungsten and bromine with the formula WBr6. It is an air-sensitive dark grey powder that decomposes above 200 °C to tungsten(V) bromide and bromine.
Per Højholt
Per Højholt (22 July 1928 – 15 October 2004) was a Danish poet. Højholt had his debut in 1948 when he published "De nøgne" (The Naked Ones), a series of poems which appeared in the magazine Heretica. His first collection was Hesten og solen, featuring religiously inspired poems. A major work came with Poetens hoved (The Head of the Poet) which appeared in 1963. This collection took a Modernist stance and meant a break with late Symbolism. Although a highly experimental and unorthodox writer, he became a popular poet. This is not least due to Gittes monologer (Gitte's Monologues). He toured the country with his recitals of these monologues which received considerable attention.

Højholt was awarded "Den store pris" from the Danish Academy in 1982 and the Holberg Medal in 1997. A recognized writer, he was included in the Danish Culture Canon in 2006 for the poem, "Personen på toppen".

Højholt was a librarian by profession and worked as such until 1966.

Holberg Medal
The Holberg Medal (Danish: Holberg-Medaljen) is an award to a Danish author of fiction or writer on science. It is awarded by the Danish association of authors, and is an appreciation of a literary or scientific work or of the award winner's authorship as a whole. The prize is often awarded on 3 December, the birthday of Ludvig Holberg. The first award was given in 1934 in connection with the 40th anniversary of the Danish association of authors.

The winner is decided by a committée consisting of 1 member from the Danish Ministry of Culture's litterature council, two representatives from the University of Copenhagen and two representatives from the Danish association of authors.
Mottsville, Nevada
Mottsville is an unincorporated community within the Humboldt–Toiyabe National Forest on the western edge of the Carson Valley in northwestern Douglas County, Nevada, United States. Mottsville is located at the junction of Nevada State Route 206 and Nevada State Route 207 3 miles (4.8 km) west-southwest of Minden.

Nevada State Route 207
State Route 207 (SR 207) is an 11.082-mile (17.835 km) state highway in western Douglas County, Nevada, United States. Commonly known as the Kingsbury Grade, it is one of three Nevada highways that connect the western edge of the state to the Lake Tahoe region through the Carson Range. The route was part of State Route 19 prior to 1976.
It Started in Naples
It Started in Naples is a 1960 American romantic comedy film directed by Melville Shavelson and produced by Jack Rose from a screenplay by Suso Cecchi d'Amico, based on the story by Michael Pertwee and Jack Davies. The Technicolor cinematography was directed by Robert Surtees. The film stars Clark Gable, Sophia Loren, Vittorio De Sica and an Italian cast. This was Gable's final film to be released within his lifetime and his last film in color.

Hal Pereira, Roland Anderson, Samuel M. Comer and Arrigo Breschi were nominated for an Oscar for its art direction

The film was released by Paramount Pictures on August 7, 1960.

Samuel M. Comer
Samuel M. Comer (July 13, 1893 – December 27, 1974) was a set decorator who worked on over 300 films during a career spanning four decades. He won four Academy Awards and was nominated for another 22 in the category Best Art Direction.

He guided his niece, Anjanette Comer, into "the biz."
Emberá-Wounaan Comarca
Emberá-Wounaan is a comarca indígena (indigenous territory) in eastern Panama. It was created by Law Number 22 on November 8, 1983, out of the former Chepigana and Pinogana districts of the Darién Province. Its capital is Unión Chocó, and it is notable for being composed of two non-contiguous sections. 12,358 people lived here in 2023, with over 95% of them being indigenous peoples.

Unión Chocó
Unión Chocó (Spanish pronunciation: [uˈnjon tʃoˈko]) is a town in the Panamanian indigenous territory (comarca indígena) of Emberá. It is located in, and is the capital of, Cémaco District.  Omar Torrijos designated the land for the village in 1969, and the first houses were built in 1970.
Samuel
Samuel is a figure who, in the narratives of the Hebrew Bible, plays a key role in the transition from the biblical judges to the United Kingdom of Israel under Saul, and again in the monarchy's transition from Saul to David. He is venerated as a prophet in Judaism, Christianity, and Islam. In addition to his role in the Jewish Bible/Old Testament, Samuel is mentioned in Jewish rabbinical literature, in the Christian New Testament, and in the second chapter of the Quran (although the text does not mention him by name). He is also treated in the fifth through seventh books of Antiquities of the Jews, written by the Jewish scholar Josephus in the first century. He is first called "the Seer" in 1 Samuel 9:9.

Prophet
In religion, a prophet or prophetess is an individual who is regarded as being in contact with a divine being and is said to be a conduit for that being, serving as an intermediary with humanity by delivering messages or teachings from the supernatural source to other people. The message that the prophet conveys is called a prophecy.

Prophethood has existed in many cultures and religions throughout history, including Mesopotamian religion, Zoroastrianism, Judaism, Christianity, Manichaeism, Islam, the Baháʼí Faith, and Thelema.
Nijūshiho
Nijūshiho or Niseishi, Nandan sho (二十四歩) (Japanese: Twenty-Four Steps) is an advanced kata practiced in Shotokan, Shitō-ryū, Chito-ryu, Ryūei-ryū, Shuri-ryū and Wadō-ryū karate.

The origin of Nijūshiho is unknown, but it is presumed that it originates from the Aragaki group like Sochin and others. This is shown through the similarity to Unsu. In introducing karate from Okinawa to Japan, Gichin Funakoshi changed the name of the kata from Niseishi to Nijūshiho. Both names mean "Twenty-Four Steps."

This kata is also practiced in Tang Soo Do and is called E Sip Sa Bo in Korean. Due to its difficulty, this kata is often reserved for advanced black belt level students. Like its Japanese and Okinawan counterparts, E Sip Sa Bo also translates to “Twenty-Four Steps.”

In Shuri-ryu this kata is taught to students achieving the rank of shodan.

Arakaki Seishō
Arakaki Seishō (新垣 世璋, 1840–1918) was a prominent Okinawan martial artist and master of Tōde who influenced the development of several major karate styles. He was known by many other names, including Aragaki Tsuji Pechin Seisho.
Podchybie, Olkusz County
Podchybie [pɔtˈxɨbjɛ] is a village in the administrative district of Gmina Trzyciąż, within Olkusz County, Lesser Poland Voivodeship, in southern Poland.

The village has an approximate population of 160.

Gmina Trzyciąż
Gmina Trzyciąż is a rural gmina (administrative district) in Olkusz County, Lesser Poland Voivodeship, in southern Poland. Its seat is the village of Trzyciąż, which lies approximately 15 kilometres (9 mi) east of Olkusz and 31 km (19 mi) north-west of the regional capital Kraków.

The gmina covers an area of 96.56 square kilometres (37.3 sq mi), and as of 2006 its total population is 7,131.

The gmina contains part of the protected area called Dłubnia Landscape Park.
Alexandre Laferrière
Alexandre Laferrière (born 1973) is a Canadian screenwriter known for working with the director Maxime Giroux.

Among his screenplays are Demain (2009) and Jo for Jonathan (Jo pour Jonathan) (2010), directed by Giroux. In meeting with Giroux at cafes to discuss their next project, Giroux said, "We'd see these women and men walking by and we just didn't know anything about them." This provided inspiration for their script Felix and Meira. Laferrière did much of the research. For the 2014 film, Laferrière won Best Screenplay at the Whistler Film Festival, and the Jutra Award for Best Screenplay.

Felix and Meira
Felix and Meira (French: Félix et Meira) is a 2014 Canadian drama film directed by Maxime Giroux, and starring Martin Dubreuil, Hadas Yaron, and Luzer Twersky. It is about an improbable affair between two Montreal residents - one a married woman from a devoutly Jewish family and community, and the other a single French Canadian man with his own family issues.

The film premiered in the Contemporary World Cinema section at the 2014 Toronto International Film Festival, where it won the Award for Best Canadian Film. It received numerous other film festival awards, and was nominated for five Canadian Screen Awards, including Best Motion Picture.
Stamatis Krestenitis
Stamatis Krestenitis (Greek: Σταμάτης Κρεστενίτης) was a Greek revolutionary leader during the Greek War of Independence.

Krestenitis was born in Elis and belonged to the Krestenitis family.  He battled in the Battle of Chlemoutsi together with Georgios Sisinis and Charalampos Vilaetis.

Elis
Elis, also known as Ellis or Ilia (Greek: Ηλεία, Eleia), is a historic region in the western part of the Peloponnese peninsula of Greece. It is administered as a regional unit of the modern region of Western Greece. Its capital is Pyrgos. Until 2011 it was Elis Prefecture, covering the same territory.

The modern regional unit is nearly coterminous with the ancient Elis of the classical period. Here lie the ancient ruins of cities of Elis, Epitalion and Olympia, known for the ancient Olympic Games which started in 776 BC.
James River
The James River is a river in Virginia that begins in the Appalachian Mountains and flows from the confluence of the Cowpasture and Jackson Rivers in Botetourt County 348 miles (560 km) to the Chesapeake Bay. The river length extends to 444 miles (715 km) if the Jackson River, the longer of its two headwaters, is included. It is the longest river in Virginia. Jamestown and Williamsburg, Virginia's first colonial capitals, and Richmond, Virginia's current capital, lie on the James River.

U.S. Route 220 in Virginia
In the U.S. state of Virginia, U.S. Route 220 (US 220) is a major north-south state highway that extends from the North Carolina state line through Roanoke to the West Virginia state line. South of Roanoke, US 220 is a four-lane highway within the proposed Interstate 73 (I-73) corridor. US 220 narrows to two lanes north of Roanoke, connecting to I-64 near Clifton Forge and then paralleling the Appalachian Mountains north-northeasterly in the direction of Cumberland, Maryland.
Alessandra Marc
Alessandra Marc, born Judith Borden (born July 29, 1957) is an American dramatic soprano who has appeared at many of the world's opera houses and orchestras. Marc is particularly known for her interpretations of the works of Richard Strauss, Richard Wagner, Giuseppe Verdi, music of the Second Viennese School, and the title role in Puccini's Turandot.

Lyric Symphony
The Lyric Symphony (German: Lyrische Symphonie), Op. 18, is a musical work for soprano and baritone soloists and large orchestra composed between 1922 and 1923 by Austrian composer Alexander Zemlinsky.
Băile Herculane
Băile Herculane (Latin: Aqua Herculis; German: Herkulesbad; Hungarian: Herkulesfürdő; Czech: Herkulovy Lázně, Turkish: Lazarethane, English: Herculean Baths) is a spa town in Romanian Banat, in Caraș-Severin County, situated in the valley of the Cerna River, between the Mehedinți Mountains to the east and the Cerna Mountains to the west, elevation 168 m (551 ft). Its current population is 3,787. The town administers one village, Pecinișca (Hungarian: Pecsenyeska; from 1912 to 1918 Csernabesenyő).

Caraș-Severin County
Caraș-Severin (Romanian pronunciation: [ˈkaraʃ seveˈrin] ⓘ) is a county (județ) of Romania on the border with Serbia. The majority of its territory lies within the historical region of Banat, with a few northeastern villages considered part of Transylvania. The county seat is Reșița. The Caraș-Severin county is part of the Danube–Criș–Mureș–Tisa Euroregion.
Raw Books
Raw Books & Graphics is an American publishing company specializing in comics and graphic novels. Operating since 1978, it is owned and operated by Françoise Mouly. The company first came to prominence publishing Raw magazine, co-edited by Mouly and her husband, cartoonist Art Spiegelman. In the 1980s the company published graphic novels, and with the formation of Raw Junior in 1999, branched into children's comics with Little Lit and Toon Books.

Gary Panter
Gary Panter (born December 1, 1950) is an American cartoonist, illustrator, painter, designer and part-time musician. Panter's work is representative of the post-underground, new wave comics movement that began with the end of Arcade: The Comics Revue and the initiation of RAW, one of the main instigators of American alternative comics. The Comics Journal has called Panter the "Greatest Living Cartoonist".

While designing for television, he remained active in comics and illustration.
Sneaky Pete Kleinow
Peter E. "Sneaky Pete" Kleinow (August 20, 1934 – January 6, 2007) was an American country-rock musician and animator. He was a member of the band the Flying Burrito Brothers, and worked extensively as a session musician, playing pedal steel guitar for Joan Baez, Jackson Browne, The Byrds, Leonard Cohen, Joe Cocker, Rita Coolidge, Eagles, The Everly Brothers, Ringo Starr, John Lennon, The Steve Miller Band, Joni Mitchell, The Rolling Stones, Stevie Wonder, Spencer Davis, Little Richard, Linda Ronstadt, Jimmie Spheeris and many others. He is a member of the Steel Guitar Hall of Fame.

Kleinow is also noteworthy for having composed the Gumby theme song as well as being an animator on the 1960s iteration of the show.

Death of a Ladies' Man (album)
Death of a Ladies' Man is the fifth studio album by Leonard Cohen, produced and co-written by Phil Spector. The album was in some ways a departure from Cohen's typical minimalist style by using Spector's Wall of Sound recording method, which included ornate arrangements and multiple tracks of instrument overdubs. The album was originally released in the US by Warner Bros., and on CD and the rest of the world by Cohen's longtime label, Columbia Records.
Message from Space: Galactic Wars
Message from Space: Galactic Wars (宇宙からのメッセージ・銀河大戦, Uchū kara no Messēji: Ginga Taisen) is a Japanese TV series written by Shotaro Ishinomori, co-produced by Toei Company and TV Asahi and aired on TV Asahi from July 8, 1978 to January 27, 1979, with a total of 27 episodes. It is a spin-off of the 1978 film Message from Space.

Message from Space
Message from Space (Japanese: 宇宙からのメッセージ, Hepburn: Uchū Kara no Messēji) is a 1978 Japanese space opera film directed by Kinji Fukasaku. It stars Sonny Chiba, Etsuko Shihomi, and Vic Morrow. Produced by Toei with a cost between the equivalent of US$5 and 6 million, it was the most expensive film made in Japan at the time.

Upon release in the United States, Message from Space received generally negative reviews from critics who not only found many similarities with the previous year's Star Wars (1977), but also felt the special effects were poorly executed in comparison to the American film. It was however nominated for Best Foreign Film at the 7th Saturn Awards in 1980.
The Three Elenas
The Three Elenas (Spanish: Las tres Elenas) is a 1954 Mexican drama film directed by Emilio Gómez Muriel and starring Amelia Bence, Manolo Fábregas, and Domingo Soler. The film's sets were designed by the art director Manuel Fontanals.

Emilio Gómez Muriel
Emilio Gómez Muriel was a prolific Mexican film director, active between the 1930s and the 1970s.

He is known for melodramas, but one of his first films was Redes (release: 1936), an attempt at social cinema with a mostly non-professional cast.

He won an award at the 1960 San Sebastian Film Festival for Simitrio.
Opojowice
Opojowice [ɔpɔjɔˈvit͡sɛ] is a village in the administrative district of Gmina Czarnożyły, within Wieluń County, Łódź Voivodeship, in central Poland. It lies approximately 3 km (2 mi) south-east of Czarnożyły, 5 km (3 mi) north of Wieluń, and 84 km (52 mi) south-west of the regional capital Łódź.

Gmina Czarnożyły
Gmina Czarnożyły is a rural gmina (administrative district) in Wieluń County, Łódź Voivodeship, in central Poland. Its seat is the village of Czarnożyły, which lies approximately 7 kilometres (4 mi) north of Wieluń and 84 km (52 mi) south-west of the regional capital Łódź.

The gmina covers an area of 69.9 square kilometres (27.0 sq mi), and as of 2006 its total population is 4,591.
Keratitis
Keratitis is a condition in which the eye's cornea, the clear dome on the front surface of the eye, becomes inflamed. The condition is often marked by moderate to intense pain and usually involves any of the following symptoms: pain, impaired eyesight, photophobia (light sensitivity), red eye and a 'gritty' sensation. Diagnosis of infectious keratitis is usually made clinically based on the signs and symptoms as well as eye examination, but corneal scrapings may be obtained and evaluated using microbiological culture or other testing to identify the causative pathogen.

Photophobia
Photophobia is a medical symptom of abnormal intolerance to visual perception of light. As a medical symptom, photophobia is not a morbid fear or phobia, but an experience of discomfort or pain to the eyes due to light exposure or by presence of actual physical sensitivity of the eyes, though the term is sometimes additionally applied to abnormal or irrational fear of light, such as heliophobia. The term photophobia comes from Greek  φῶς (phōs) 'light' and  φόβος (phóbos) 'fear'.
Romanta T. Miller House
Romanta T. Miller House, also known as the Fraser Farm, is a historic home located at Wheatland, Monroe County, New York. It was built in 1869–1870, and is a two-story, Italianate style brick and masonry dwelling. The house has a 1+1⁄2-story rear kitchen addition. It sits on a cut limestone foundation and has an overhanging slate roof. It features a Colonial Revival full height entrance and sleeping porch designed by architect Claude Fayette Bragdon and added in 1914.  Also on the property are the contributing large U-shaped barn (c. 1870, 1940) and a small garden shed / machine shop.: 3, 8

It was listed on the National Register of Historic Places in 2014.

Claude Fayette Bragdon
Claude Fayette Bragdon (August 1, 1866 – 1946) was an American architect, writer, and stage designer based in Rochester, New York, up to World War I, then in New York City.

The designer of Rochester’s New York Central Railroad terminal (1909–13) and Chamber of Commerce (1915–17), as well as many other public buildings and private residences, Bragdon enjoyed a national reputation as an architect working in the progressive tradition associated with Louis Sullivan and Frank Lloyd Wright. Along with members of the Prairie School and other regional movements, these architects developed new approaches to the planning, design, and ornamentation of buildings that embraced industrial techniques and building types while reaffirming democratic traditions threatened by the rise of urban mass society. In numerous essays and books, Bragdon argued that only an “organic architecture” based on nature could foster a democratic community in an industrial capitalist society.
Panos Panay (music executive)
Panos Andreas Panay (born Panayiotis Andreas Panayiotou; June 25, 1972) is a Cyprus-born entrepreneur, executive and author. Panay currently holds the post of President of the Recording Academy alongside  CEO Harvey Mason Jr. Previously he was the Senior Vice President of Global Strategy & Innovation at Berklee College of Music. He founded Berklee Institute for Creative Entrepreneurship, and founded the online platform Sonicbids, which was later acquired by Backstage Magazine. Panay is a Fellow at MIT Connection Science at the MIT Media Lab, and also founded the Open Music Initiative.

Open Music Initiative
The Open Music Initiative is an initiative led by the Berklee College of Music Institute for Creative Entrepreneurship (BerkleeICE) in collaboration with the MIT Media Lab and with support from a number of major music labels, streaming services, publishers, collection societies and nearly 60 other founding entities. The mission of Open Music Initiative is to promote and advance the creation of open source standards and innovation related to music to help assure proper compensation for all creators, performers and rights holders of music.
Lochmaben Castle
Lochmaben Castle is a ruined castle in the town of Lochmaben, the feudal Lordship of Annandale, and the united county of Dumfries and Galloway. It was built by Edward I in the 14th century replacing an earlier motte and bailey castle, and later rebuilt during the reign of James IV of Scotland. The earlier motte-and-bailey castle was built south of the current castle in c. 1160 by the Bruce family, Lords of Annandale.

Clan Bruce
Clan Bruce (Scottish Gaelic: Brùs) is a Lowlands Scottish clan. It was a royal house in the 14th century, producing two kings of Scotland (Robert the Bruce and David II), and a disputed High King of Ireland, Edward Bruce.
Hamelin Prison
Hamelin Prison, also known as the Stockhof, was a prison and penitentiary in Hamelin. The penal institution, which had a predecessor since 1698, existed from 1827 to 1980. It was located between the old town and the river Weser. After the Second World War, it was the site of executions carried out by the occupying British forces.

The listed prison buildings are now used as a hotel.

Fritz Klein
Fritz Klein (24 November 1888 – 13 December 1945) was a Romanian-German Nazi doctor and war criminal, hanged for his role in atrocities at Auschwitz concentration camp and Bergen-Belsen concentration camp during the Holocaust.
Georgia State Route 115
State Route 115 (SR 115) is a 32.3-mile-long (52.0 km) state highway that runs west-to-east in the northeastern part of the U.S. state of Georgia. It travels through portions of Lumpkin, White, and Habersham counties.

Habersham County, Georgia
Habersham County is a county in the Northeast region of the U.S. state of Georgia. As of the 2020 census, the population was 46,031. The county seat is Clarkesville. The county was created on December 15, 1818, and named for Colonel Joseph Habersham of the Continental Army in the Revolutionary War. Habersham County comprises the Cornelia, GA Micropolitan Statistical Area.