hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Chronotropic
Chronotropic effects (from chrono-, meaning time, and tropos, "a turn") are those that change the heart rate.

Chronotropic drugs may change the heart rate and rhythm by affecting the electrical conduction system of the heart and the nerves that influence it, such as by changing the rhythm produced by the sinoatrial node. Positive chronotropes increase heart rate; negative chronotropes decrease heart rate.

A dromotrope affects atrioventricular node (AV node) conduction. A positive dromotrope increases AV nodal conduction, and a negative dromotrope decreases AV nodal conduction. A lusitrope is an agent that affects diastolic relaxation.

Many positive inotropes affect preload and afterload.

Sinoatrial node
The sinoatrial node (also known as the sinuatrial node, SA node, sinus node or Keith–Flack node) is an oval shaped region of special cardiac muscle in the upper back wall of the right atrium made up of cells known as pacemaker cells. The sinus node is approximately 15 mm long, 3 mm wide, and 1 mm thick, located directly below and to the side of the superior vena cava.

These cells produce an electrical impulse known as a cardiac action potential that travels through the electrical conduction system of the heart, causing it to contract. In a healthy heart, the SA node continuously produces action potentials, setting the rhythm of the heart (sinus rhythm), and so is known as the heart's natural pacemaker. The rate of action potentials produced (and therefore the heart rate) is influenced by the nerves that supply it.
Kegelite
Kegelite is a complex silicate mineral with formula Pb8Al4Si8O20(SO4)2(CO3)4(OH)8.

It was first described in 1975 for an occurrence in the Tsumeb Mine, Tsumeb, Otjikoto Region, Namibia and named for Friedrich Wilhelm Kegel (1874–1948), Director of mining operations at Tsumeb.
It occurs in a deeply oxidized polymetallic ore deposits in Tsumeb. Associated minerals include quartz, galena, mimetite, hematite, leadhillite, anglesite, fleischerite, melanotekite and alamosite. It has also been reported from the Zeehan district in Tasmania and from Tune, Sarpsborg, Østfold, Norway.

Fleischerite
Fleischerite is a white to light-reddish pink sulfate mineral. It is named after Michael Fleischer, a co-founder of the International Mineralogical Association. Fleischerite was first recognized as a mineral in 1960. Fleischerite is the namesake of its own mineral group, which also includes schaurteite, despujolsite, mallestigite, and genplesite. It is often confused with dundasite.
Randy Hahn
Randy Hahn (born October 21, 1958) is a Canadian-American play-by-play commentator for the San Jose Sharks on NBC Sports California, and has held that position for over 30 seasons. He has over 40 years of broadcast experience, mostly in hockey. Randy Hahn has worked the Stanley Cup Playoffs for TNT since 2022.
He broadcast his 2,000th Sharks game on December 13, 2022, when the Sharks faced the Arizona Coyotes in San Jose. Along with analyst Drew Remenda, Hahn has won five Northern California Emmy Awards in the "On Camera Sports" section; one in 1999, and others in 2002, 2005, and 2008. Hahn was a PBP announcer in Konami's NHL Blades of Steel '99 and 2K Sports' NHL 2K9, NHL 2K10, and NHL 2K11.

NBC Sports California
NBC Sports California (sometimes abbreviated as NBCS California) is an American regional sports network owned by the NBC Sports Group unit of NBCUniversal, and operates as an affiliate of NBC Sports Regional Networks. The channel broadcasts regional coverage of professional and college sports events throughout Northern California, as well as original sports-related news, discussion and entertainment programming.

NBC Sports California is available on cable and fiber optic television providers throughout northern and southern California, and portions of Oregon and western Nevada. It is also available nationwide on satellite via DirecTV. The network maintains main studios and offices headquartered with sister network NBC Sports Bay Area in San Francisco, California.
19th Politburo of the Chinese Communist Party
The 19th Politburo of the Chinese Communist Party (CCP), formally the Political Bureau of the 19th Central Committee of the Communist Party of China, was elected at the 1st plenary session of the 19th Central Committee of the CCP on 25 October 2017 in the aftermath of the 19th National Congress. This electoral term was preceded by the 18th Politburo and succeeded by the 20th. Seven of the 25 members served in the 19th Politburo Standing Committee.

20th Politburo of the Chinese Communist Party
The 20th Politburo of the Chinese Communist Party (CCP), formally the Political Bureau of the 20th Central Committee of the Communist Party of China was elected at the 1st plenary session of the 20th Central Committee of the CCP on 23 October 2022 in the aftermath of the 20th National Congress. This electoral term was preceded by the 19th Politburo. Seven of the 24 members serve in the 20th Politburo Standing Committee.

The 20th CCP Politburo was noted as the first to include a former Minister of State Security and the first Politburo with no women in 25 years. All members are Han Chinese, the majority ethnic group in the country. According to informal party convention, party leaders aged 68 or above are not eligible to remain in the Politburo but the 20th reelected three members past that age.
West Virginia Route 90
West Virginia Route 90 is a 13-mile (21 km) long north–south state highway in the Eastern Panhandle of West Virginia. The route, located within Tucker County and Grant County, runs parallel to the Maryland state line for most of its length. The southern terminus of the route is at U.S. Route 219 one mile (1.6 km) north of Thomas. The northern terminus is at U.S. Route 50 (the Northwestern Turnpike) in Gormania less than 200 yards (180 m) east of the North Branch Potomac River.

Tucker County, West Virginia
Tucker County is a county in the U.S. state of West Virginia. As of the 2020 census, the population was 6,762, making it West Virginia's fourth-least populous county. Its county seat is Parsons. The county was created in 1856 from a part of Randolph County, then part of Virginia. In 1871, a small part of Barbour County, was transferred to Tucker County. The county was named after Henry St. George Tucker, Sr., a judge and Congressman from Williamsburg, Virginia.
1977 Comorian presidential referendum
A referendum on the presidency of Ali Soilih was held in the Comoros on 28 October 1977. The result was 57% in favour and 43% against, with a 92% voter turnout. Despite the backing, Soilih was overthrown on 13 May 1978 by forces hired by exiled former leader Ahmed Abdallah, who was restored to power.

Ali Soilih
Ali Soilih M'Tsashiwa (Arabic: علي صويلح; January 7, 1937 – May 29, 1978) was a Comorian socialist revolutionary and political figure who served as the third President of the Comoros from 3 January 1976 until a French-backed coup-d'etat toppled him in 13 May 1978. Soilih was then captured, tortured with a bayonet and killed while trying to escape.
Joliet Gateway Center
Joliet Gateway Center is a multimodal mass transit center in downtown Joliet, Illinois. It opened in 2018, replacing the nearby Joliet Union Station as the commuter and passenger train station serving Joliet.

The station is the terminus of the Metra Rock Island District and Heritage Corridor, and an intermediate stop for the Amtrak Texas Eagle and Lincoln Service trains. The station's bus terminal opened in 2021, and serves 10 Pace bus routes.

Joliet, Illinois
Joliet (/ˈdʒoʊliɛt, ˌdʒoʊliˈɛt/ JOH-lee-et, -⁠ET) is a city in Will and Kendall counties in the U.S. state of Illinois. Located 40 miles (64 km) southwest of Chicago, it is the county seat of Will County. The population was 150,362 at the 2020 census, making it the third-most populous city in Illinois.
Grand Meadow National Nature Park
The Grand Meadow National Nature Park (Ukrainian: Національний природний парк
«Великий Луг», romanized: Velykyj Luh) covers historic steppe terrain in southeast Ukraine. It is on the south bank of the Dnieper River's Kakhovka Reservoir, which was created by the Dnieper Hydroelectric Station. The meadows and reed beds on the shore support one of the largest transmigration spots for birds in Eastern Europe. The park is in the administrative district of Vasylivka Raion in Zaporizhzhia Oblast.

Vasylivka Raion
Vasylivka Raion (Ukrainian: Василівський район) is one of the five raions (districts) of Zaporizhzhia Oblast in southern Ukraine. The administrative center of the region is the town of Vasylivka. Population: 181,271 (2022 estimate).

On 18 July 2020, as part of the administrative reform of Ukraine, the number of raions of Zaporizhzhia Oblast was reduced to five, and the area of Vasylivka Raion was significantly expanded.  The January 2020 estimate of the raion population was 60,962 (2020 est.).
Gurkha Reserve Unit
4°56′21″N 114°58′28″E﻿ / ﻿4.9390340°N 114.9743814°E﻿ / 4.9390340; 114.9743814

The Gurkha Security Unit (GSU; Malay: Pasukan Sekuriti Gurkha, Jawi: ڤاسوكن سيکوريتي ڬورخا‎), formerly known as Gurkha Reserve Unit (GRU; Malay: Pasukan Simpanan Gurkha, PSG; also referred to as the Royal Brunei Gurkha Reserve Unit), is a Bruneian special elite guard force and royal guard consisting of Gurkhas from Nepal.

Royal guard
A royal guard (also called a palace guard) is a group of military bodyguards, soldiers, or armed retainers responsible for the protection of a royal family member, such as a king or queen, or prince or princess. They often are an elite unit of the regular armed forces, or are designated as such, and may maintain special rights or privileges.
Sunset Hill (Warren, New York)
Sunset Hill, also known as Mrs. Eugene D. Stocker Estate, is a historic home complex located just north of the Village of Richfield Springs in the Town of Warren in Herkimer County, New York. It includes a main house, guest house, equipment barn, stable, stone entrance gate, swimming pool, and garden. The main house was built in 1923 and is a two-story, gable roofed, wood frame Colonial Revival style building sheathed in clapboard siding with a wood shingle roof.  It features a tall portico with square columns and a triangular pediment.  The complex was designed by Dwight James Baum (1886–1939) as a seasonal estate for Mrs. Eugene D. Stocker.

It was listed on the National Register of Historic Places in 2007.

Warren, New York
There is also a Warren County, and a hamlet of Warren.

Warren is a town in Herkimer County, New York, United States. The population was 1,143 at the 2010 census. The town is named after General Joseph Warren, who was killed at the Battle of Bunker Hill. Warren is in the south part of Herkimer County. US 20 passes across the town.
Queen Anne High School, Seattle
Queen Anne High School (1909–1981) was a Seattle Public Schools high school on Galer Street atop Queen Anne Hill in Seattle, Washington, United States. The building was converted to condominium apartments in 2007.

The school was built in 1908 with additions in 1929 and 1955, and was listed on the National Register of Historic Places in 1985. It is also an official City of Seattle landmark.

The school closed in 1981 due to decreasing enrollment.  Students in the school's attendance area transferred to various high schools in the district. The school facility underwent renovation and adaptive reuse to become a residential apartment building in 1986, with 137 apartments. In 2006 the residential apartments underwent another renovation and converted to condominium units.

Seattle Public Schools
Seattle Public Schools is the largest public school district in the state of Washington. The school district serves almost all of Seattle. Additionally it includes sections of Boulevard Park and Tukwila. As of the 2021–2022 academic year, 106 schools are operated by the district, which serve 51,650 students throughout the city.
Roger Fry
Roger Eliot Fry (14 December 1866 – 9 September 1934) was an English painter and critic, and a member of the Bloomsbury Group. Establishing his reputation as a scholar of the Old Masters, he became an advocate of more recent developments in French painting, to which he gave the name Post-Impressionism. He was an early figure to raise public awareness of modern art in Britain, and he emphasised the formal properties of paintings over the "associated ideas" conjured in the viewer by their representational content. He was described by the art historian Kenneth Clark as "incomparably the greatest influence on taste since Ruskin ... In so far as taste can be changed by one man, it was changed by Roger Fry". The taste Fry influenced was primarily that of the Anglophone world, and his success lay largely in alerting an educated public to a compelling version of recent artistic developments of the Parisian avant-garde.

Art critic
An art critic is a person who is specialized in analyzing, interpreting, and evaluating art. Their written critiques or reviews contribute to art criticism and they are published in newspapers, magazines, books, exhibition brochures, and catalogues and on websites. Some of today's art critics use art blogs and other online platforms in order to connect with a wider audience and expand debate.
Burking Poor Old Mrs Constitution
Burking Poor Old Mrs Constitution is an 1829 satirical cartoon by the British illustrator William Heath. An attack on the Catholic Emancipation measures brought in by the Duke of Wellington's Tory Government it portrays this as a murder act equivalent to those committed by the notorious killers Burke and Hare over a period of ten months in 1828 in Edinburgh, Scotland. Wellington and his henchman Robert Peel are shown suffocating "Old Mrs Constitution", aged 141 years (a reference to the Glorious Revolution of 1688). With the defeat of the supremacy of the Church of England, a Roman Catholic priest is shown entering the door to purchase the corpse.

Copies exist today in the British Museum and National Portrait Gallery in London and the Philadelphia Museum of Art in Pennsylvania.

William Heath (artist)
William Heath (1795 – 7 April 1840) was an English artist who once described himself as a "portrait & military painter." He was best known for his published engravings which included caricatures, political cartoons, and commentary on contemporary life.
Whittier, California
Whittier (/ˈhwɪtiər/) is a city in Los Angeles County, California, United States. Part of the Gateway Cities, the 14.7-square-mile (38.0 km2) city had 87,306 residents as of the 2020 United States census. Whittier was incorporated in February 1898 and became a charter city in 1955. The city is named for the Quaker poet John Greenleaf Whittier and is home to Whittier College. The city is surrounded by four unincorporated areas sharing the Whittier name, West Whittier-Los Nietos, North Whittier, South Whittier, and East Whittier, which combined are home to a larger population than Whittier proper.

North Whittier, California
North Whittier is an unincorporated community in Los Angeles County in the U.S. state of California. The population was 4,351 according to the 2000 census.

North Whittier is home to Rio Hondo College and Rose Hills Memorial Park, which claims to be the largest cemetery in North America.
Irondro
Irondro is a village in the region of Vatovavy in Madagascar. It belongs to the municipality of Antsenavolo and the district of Mananjary/ It is situated at the crossroad of the Route nationale 25  between Ranomafana, Ifanadiana  and Mananjary and is the startpoint of the Route nationale 12 to Manakara (118km) and Farafangana.

Route nationale 25 (Madagascar)
Route nationale 25 (RN 25) is a primary highway in Madagascar of 161 km, running from Mananjary, Fianarantsoa to RN7. It crosses the regions of Vatovavy and Haute Matsiatra.
It is only partly paved and often in bad condition.
Bradford Beck
Bradford Beck is a river that flows through Bradford, West Yorkshire, England, (then Bradford Dale) and on to the River Aire at Shipley. As it reaches Bradford city centre it runs underground after being built over in the 19th century. It is culverted as it runs from Bradford city centre to Queen's Road after which it runs mostly in an open channel to Shipley. The beck used to be known as the filthiest river in England.

Bradford itself is so named after a crossing on Bradford Beck (the Broad Ford) which was located near to what is present day Church Street in the city centre, with a crossing named as Broadstones. The beck is formed from a number of smaller watercourses, namely Pinch Beck, Pitty Beck, Middlebrook, Clayton Beck, Bull Greave Beck, Chellow Dene Beck, Westbrook, Dirkhill Beck, Bowling Beck, Eastbrook, Bolton Beck, Trap Sike, Northcliffe Beck and Red Beck.

Shipley, West Yorkshire
Shipley is a historic market town and civil parish in the City of Bradford, West Yorkshire, England. Located on the River Aire and the Leeds and Liverpool Canal, Shipley is directly north of the city of Bradford. The population of Shipley at the 2011 Census was 15,483.

Until 1974, Shipley was an urban district in the West Riding of Yorkshire. The town forms a continuous urban area with Bradford.
Enarodustat
Enarodustat (development code JTZ-951; brand name Enaroy) is a drug used for the treatment of anemia, especially when associated with chronic kidney disease (CKD).  Enarodustat functions as a inhibitor of hypoxia inducible factor-proly hydroxylase (HIF-PH).

The drug was approved in September 2020 in Japan for anemia associated with CKD and is currently in clinical development in the United States and South Korea.  The drug is being developed by Japan Tobacco and JW Pharmaceutical.

HIF prolyl-hydroxylase inhibitor
Hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) are a novel class of oral medications developed for the treatment of anemia in chronic kidney disease (CKD). These drugs work by inhibiting hypoxia-inducible factor-proline dioxygenase (HIF prolyl-hydroxylase), which are responsible for the degradation of hypoxia-inducible factor (HIF) under normal oxygen conditions. By stabilizing HIF, these inhibitors mimic the body's natural response to hypoxia, leading to increased endogenous erythropoietin production and improved iron metabolism. HIF-PHIs have shown efficacy in correcting and maintaining hemoglobin levels in both dialysis-dependent and non-dialysis-dependent CKD patients, offering an alternative to traditional erythropoiesis-stimulating agents (ESAs).
Tianjin TEDA Company
Tianjin TEDA Co., Ltd. is a Chinese conglomerate based in Tianjin, China which engaged in many business areas. It is involved in the businesses of garments, ecological products, transportation operations, medicines and nutrition products.

TEDA is the acronym of Tianjin Economic-Technological Development Area.

As at 8 November 2016, Tianjin TEDA is a consistent of SZSE Component Index but not in SZSE 300 Index, making the company was ranked between the 301st to 500th by free float adjusted market capitalization.

Tianjin Economic-Technological Development Area
Tianjin Economic-Technological Development Area (simplified Chinese: 天津经济技术开发区; traditional Chinese: 天津經濟技術開發區; pinyin: tiānjīn jīngjì jìshù kāifā qū), commonly abbreviated as TEDA (simplified Chinese: 泰达; traditional Chinese: 泰達; pinyin: tài dá; lit. 'peace and prosperity') is the main free market zone in Binhai, Tianjin, China. It was formed in late 1984.
Tiana's Bayou Adventure
Tiana's Bayou Adventure is a log flume attraction at Magic Kingdom and Disneyland. It is based on Walt Disney Animation Studios' 2009 film The Princess and the Frog. The ride experience begins with an outdoor float-through that leads to indoor dark ride segments, with a climactic steep drop followed by an indoor finale. The drop is 52.5 feet (16.0 meters). The attraction, which replaced Splash Mountain, opened on June 28, 2024 at Magic Kingdom and on November 15, 2024 at Disneyland.

Log flume (ride)
Log flumes (colloquially known as log rides) are amusement rides consisting of a water flume and (artificial) hollow logs or boats. Passengers sit in the logs, which are propelled along the flume by the flow of water.

The ride usually culminates with a rapid descent and splashdown into a body of water, which may happen more than once (normally the largest drop being just before the end). It provides people with a way to get wet and cool off on a hot summer day, with certain seating sections usually being splashed with more water. Log flume rides are named for log flumes used in logging.
2024–25 Colgate Raiders men's basketball team
The 2024–25 Colgate Raiders men's basketball team represented Colgate University in the 2024–25 NCAA Division I men's basketball season. The Raiders, led by 14th-year head coach Matt Langel, played their home games at Cotterell Court located in Hamilton, New York as members of the Patriot League. They finished the season 14–19, 10–8 in Patriot League play to finish in a tie for third place. They defeated Army in the quarterfinals of the Patriot League tournament before losing to American in the semifinals. As a result, and for the first time since 2018, the Raiders failed to qualify for the NCAA tournament.

2024–25 American Eagles men's basketball team
The 2024–25 American Eagles men's basketball team represented American University during the 2024–25 NCAA Division I men's basketball season. The Eagles, led by second-year head coach Duane Simpkins, played their home games at Bender Arena in Washington, D.C. as members of the Patriot League. They finished the season 22–13, 13–5 in Patriot League play, to finish as co-regular season champions. As the No. 2 seed in the Patriot League tournament, they defeated Lafayette, Colgate, and Navy to win the tournament championship. As a result, they received the conference's automatic bid to the NCAA tournament. As a No. 16 seed in the East Region, they lost to Mount St. Mary's in the First Four.
Leper Queen
The Leper Queen is a supervillain appearing in American comic books published by Marvel Comics. She is the masked leader of the Sapien League, an extremist anti-mutant organization that is similar to Friends of Humanity.

Techno-organic virus
The techno-organic virus is a fictional virus appearing in American comic books published by Marvel Comics. In the comics, the techno-organic virus transforms organic material into techno-organic material, which resembles both machinery and living tissue. All techno-organic cells function like independent machines, and carry both the virus and all information on their carriers. This includes memories and appearance, allowing a damaged techno-organic being to rebuild itself from a single cell.

Variants of the virus include the Transmode Virus carried by the Technarchy, and Apocalypse's variant, which was created by Mister Sinister and used by Apocalypse.
Bucket (song)
"Bucket" is a song by Canadian singer-songwriter Carly Rae Jepsen, released in April 4, 2009 as the second single from her debut studio album, Tug of War. The song peaked at number 32 on the Canadian Hot 100. "Bucket" contains elements from "There's a Hole in My Bucket".

There's a Hole in My Bucket
"There's a Hole in My Bucket" (or "...in the Bucket") is a "humorous", classic children's folk song based on a protracted dialogue between two characters, Henry and Liza, about a leaky bucket. Various versions exist but they differ only slightly, all describing a "deadlock" situation essentially as follows: Henry's bucket leaks, so Liza tells him to repair it. To fix the leaky bucket, he needs straw. To cut the straw, he needs a knife. To use the knife, he needs to sharpen it. If the sharpening stone must be damp, he needs water. But to fetch water, he needs the bucket... which has a hole in it.

To commemorate the song, the National Day Calendar organization in Mandan, North Dakota, claims that May 30 every year is "Hole in My Bucket Day".