hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
2'-5'-oligoadenylate synthase
In molecular biology, 2'-5'-oligoadenylate synthetase (2-5A synthetase) is an enzyme (EC 2.7.7.84) that reacts to interferon signal. It is an antiviral enzyme that counteracts viral attack by degrading RNAs, both viral and host. The enzyme uses ATP in 2'-specific nucleotidyl transfer reactions to synthesize 2'-5'-oligoadenylates, which activate latent ribonuclease (RNase-L), resulting in degradation of viral RNA and inhibition of virus replication.

The C-terminal half of 2'-5'-oligoadenylate synthetase, also referred to as domain 2 of the enzyme, is largely alpha-helical and homologous to a tandem ubiquitin repeat. It carries the region of enzymatic activity between at the extreme C-terminal end.

Ribonuclease L
Ribonuclease L or RNase L (for latent), known sometimes as ribonuclease 4 or 2'-5' oligoadenylate synthetase-dependent ribonuclease, is an interferon (IFN)-induced ribonuclease which, upon activation, destroys all RNA within the cell (both cellular and viral) as well as inhibiting mRNA export.  RNase L is an enzyme that in humans is encoded by the RNASEL gene.

This gene encodes a component of the interferon-regulated 2'-5'oligoadenylate (2'-5'A) system that functions in the antiviral and antiproliferative roles of interferons. RNase L is activated by dimerization, which occurs upon 2'-5'A binding, and results in cleavage of all RNA in the cell. This can lead to activation of MDA5, an RNA helicase involved in the production of interferons.
Motoko Arai
Motoko Arai (新井素子; born August 8, 1960) is a Japanese science fiction and fantasy writer. Her writing is characterized by her use of a light conversational tone geared towards a young adult audience. She has published three series of novels and several short stories. Her works, Green Requiem and Neptune, received the Seiun Award for short story in 1981 and 1982.

Japanese science fiction
Science fiction  is an important genre of modern Japanese literature that has strongly influenced aspects of contemporary Japanese pop culture, including anime, manga, video games, tokusatsu, and cinema. Japanese fiction has assumed a position of significance in many genres of world literature, with speculative fiction encompassing a diverse range of literary works, has a rich history deeply intertwined with the country's cultural and social contexts, It is Often characterized by its imaginative narratives, futuristic themes, and exploration of societal issues, It has gained international recognition for its unique blend of traditional storytelling elements with modern speculative concepts. Contemporary Japanese speculative fiction has themes focusing on artificial intelligence, genetic engineering, and environmental degradation are prevalent, reflecting the anxieties and realities of the modern world.
Giant Orange
Giant Orange is the third studio album by rock group Cheap Girls, released on February 21, 2012. It was the first release for the band after signing with Rise Records and is available on CD, vinyl and as a digital download. The album was produced by Laura Jane Grace of American punk rock band Against Me! and was the first time the band worked with a producer. With the exception of tambourine, the album was recorded using only guitar, bass, drums and vocals. The track "Gone All Summer" is the introduction music on Kyle Kinane's "Whiskey Icarus" stand-up comedy special released on CD and DVD.

Cheap Girls
Cheap Girls were an American rock band from Lansing, Michigan. The band consisted of brothers Ian Graham (guitar, lead vocals) and Ben Graham (drums, back-up vocals), Jason Draper (Bass) and Adam Aymor (guitar). Formed in 2007, the band quickly began recording and touring, releasing their first album, Find Me a Drink Home in 2008. Together, they released four full-length studio albums. The band toured with bands such as Against Me!, The Gaslight Anthem, The Hold Steady, and The Bouncing Souls across the US and Europe. Their sound was often compared to The Replacements, The Lemonheads, and early Smoking Popes.
WaterCar
WaterCar is an American company that specializes in the manufacture and development of luxury amphibious vehicles. Based in Southern California, the company was founded by Dave March in 1999 when he was inspired by the Amphicar of the 1960s. March claims he originally had no plans to market an amphibious vehicle – just merely to build one. In 2013, the company released its first commercial vehicle, the Panther, which holds a top speed of 80 mph (130 km/h) on land and 45 mph (72 km/h) on water. The company holds 27 amphibious related patents as well as the Guinness World Record for the fastest amphibious vehicle. WaterCar vehicles are designed and manufactured at Fountain Valley BodyWorks, an 85,000 square feet (7,900 m2) collision repair auto body shop in Southern California, owned and operated by March.

Amphibious vehicle
An amphibious vehicle (or simply amphibian) is a vehicle that works both on land and on or under water. Amphibious vehicles include amphibious bicycles, ATVs, cars, buses, trucks, railway vehicles, combat vehicles, and hovercraft.

Classic landing craft are not amphibious vehicles as they do not work on land, although they are part of amphibious warfare. Ground effect vehicles, such as ekranoplans, would likely crash on any but the flattest of landmasses so are also not considered to be amphibious vehicles.
Theodor Hoffmann (admiral)
Theodor Hoffmann (27 February 1935 – 1 November 2018) was an East German Admiral who served as the head of the People's Navy (Volksmarine) and as the last Minister of National Defense of the German Democratic Republic and head of the National People's Army.

Volksmarine
The Volksmarine (VM, German pronunciation: [ˈfɔlksmaˌʁiːne]; English: People's Navy) was the naval force of the German Democratic Republic (GDR) from 1956 to 1990. The Volksmarine was one of the service branches of the National People's Army and primarily performed a coastal defence role along the GDR's Baltic Sea coastline and territorial waters.

Disbanded one day before the official reunification of Germany, the Volksmarine served as the naval arm of the East German state for 34 years. Rostock, former home port and headquarters of the Volksmarine, houses Navy Command for the post-reunification Deutsche Marine.
Krull (video game)
Krull is an Atari 2600 video game based on the film of the same name and published in 1983 by Atari, Inc. It was written by Dave Staugas, who later ported Millipede to the 2600. Gottlieb manufactured an arcade shooter of the same name in the same year, but it is unrelated to the Atari 2600 game other than sharing the Krull license.

Gottlieb
Gottlieb (formerly D. Gottlieb & Co.) was an American arcade game corporation based in Chicago, Illinois. It is best known for creating a vast line of pinball machines and arcade games (including Q*bert) throughout much of the 20th century.
Sue Green
Susan Tex Green (born August 13, 1953) is an American professional wrestler. She began wrestling at the age of 15 and was trained by Joe Blanchard. She was the frequent tag team partner of Sandy Parker, with whom she won the National Wrestling Alliance (NWA)'s NWA Women's World Tag Team Championship. The title reign, however, is unrecognized. In 1976, Green was recognized by Pro Wrestling Illustrated as the Girl Wrestler of the Year. In 1992, she joined the Professional Girl Wrestling Association, holding the promotion's championship and later acting as commissioner.

Ladies Professional Wrestling Association
The Ladies Professional Wrestling Association (LPWA) was a women's professional wrestling promotion which operated in the early 1990s (ca. 1989–1992). It was considered a successor to such women's promotions as Gorgeous Ladies of Wrestling (GLOW), but it differed in that, while GLOW slanted more toward WWF-style sports entertainment, the LPWA treated its product seriously and put its primary emphasis on in-ring athletics.
McCorkell
McCorkell is a surname. Notable people with the surname include:

Aileen McCorkell, founder of the Derry Branch of the Red Cross

David McCorkell (born 1955), Lord Lieutenant of County Antrim (from 2019)

Sir Dudley McCorkell (1883–1960), Mayor of Londonderry (1929–1935), and ex officio member of the Senate of Northern Ireland and former Lord Lieutenant of County Londonderry

Gordon McCorkell (born 1983), Scottish actor

Jenna McCorkell (born 1986)) is a British figure skater from Coleraine

Jock McCorkell (born 1918), former Australian rules footballer in the Victorian Football League

Lisa McCorkell, American public health researcher

Colonel Sir Michael McCorkell (1925–2006), former Lord Lieutenant of County Londonderry, Northern Irish soldier and public servant

Neil McCorkell, wicketkeeper for Hampshire County Cricket Club

Ross McCorkell, Scottish-American drag queen

Aileen McCorkell
Aileen Allen McCorkell, Lady McCorkell OBE (née Booth; 18 September 1921 – 25 December 2010) was the founder and first President of the British Red Cross branch in Derry. In 1972, she and her husband, Colonel Sir Michael McCorkell, hosted secret peace talks between the British Government and the Provisional IRA, whose delegation included Gerry Adams.
Angelina River
The Angelina River is formed by the confluence of Barnhardt and Shawnee creeks 3 miles (5 km) northwest of Laneville in southwest central Rusk County, Texas, United States.

A tributary of the Neches River, the river flows southeast for 120 miles (193 km) and forms the boundaries between Cherokee and Nacogdoches, Angelina and Nacogdoches, and Angelina and San Augustine counties. It passes under US 59 via former Angelina River Bridge. It empties into the Neches River 12 miles (19 km) north of Jasper in northwestern Jasper County.

The Sam Rayburn Reservoir is on the southern part of the river.

Angelina River Bridge
The Angelina River Bridge was a historic bridge on U.S. Route 59 (US 59) over the Angelina River in Lufkin, Texas. It was built in 1935 and added to the National Register of Historic Places in 1988.

It was a poured concrete bridge supported by concrete piers, poured in sections about 25 feet (7.6 m) long.  It had square balusters and rails with chamfered edges.

The bridge was demolished and replaced with a new bridge in 1998.
Zakhmee
Zakhmee is a 1975 Hindi movie. Produced by Tahir Hussain, the film was directed by Raja Thakur. It stars Sunil Dutt, Asha Parekh, Rakesh Roshan, Reena Roy, Tariq, Helen, Johnny Walker, Agha, Iftekhar in pivotal roles. The music was composed by Bappi Lahiri, who later said that this film was his first claim to fame. The film performed "Above Average" at the box office, according to one source.

Raja Thakur
Raja Thakur (1923–1975) was an Indian film director who primarily worked in the Marathi film industry. He is best known for his films Me Tulas Tujhya Angani (1955), Rangalya Ratree Ashya (1962), Ektee (1968), Mumbaicha Jawai (1970), Gharkul (1971) and Jawai Vikat Ghene Aahe (1972); for which he won National and State-level awards.
Barmer Assembly constituency
Barmer Assembly constituency is one of the 200 Legislative Assembly constituencies of Rajasthan state in India. It was established in 1962, with its first representative being Umed Singh.

It comprises Barmer tehsil, in Barmer district. As of 2023, it is represented by Priyanka Chaudhary, an Independent mla.

Priyanka Chaudhary
Priyanka  Chaudhary (born 1973) is an Indian politician and doctor from Barmer, Rajasthan. She was elected to the 16th Rajasthan Legislative Assembly from Barmer. She is the grand-daughter of Gangaram Choudhary, cabinet minister in Government of Rajasthan.
2008 United States House of Representatives elections in Tennessee
The 2008 congressional elections in Tennessee was held on November 4, 2008, to elect the 9 U.S. representatives from the state of Tennessee, one from each of the state's nine congressional districts.

Following the 2008 elections, no seats changed hands, leaving the Tennessee delegation at a 5-4 Democratic majority. As of 2026, this was the last time Democrats won a majority of congressional districts from Tennessee's House delegation, as well as the House popular vote.

Lincoln Davis
Lincoln Edward Davis (born September 13, 1943) is an American politician and businessman who served as the U.S. representative for Tennessee's 4th congressional district from 2003 to 2011. Prior to his election to Congress, Davis served in the Tennessee General Assembly from 1980 to 2002. A member of the Democratic Party, he is a member of the ReFormers Caucus of Issue One.
Kake, Hiroshima
Kake (加計町, Kake-chō) was a town located in Yamagata District, Hiroshima Prefecture, Japan.

As of 2003, the town had an estimated population of 4,315 and a density of 44.91 persons per km2. The total area was 96.09 km2. The town was the birthplace of Imperial Japanese Navy aviator and later politician Minoru Genda.

On October 1, 2004, Kake, along with the town of Togouchi, and the village of Tsutsuga (all from Yamagata District), was merged to create the town of Akiōta.

Minoru Genda
General Minoru Genda (源田 実, Genda Minoru; 16 August 1904 – 15 August 1989) was an Imperial Japanese Navy flight officer, JASDF general and politician. He is best known for helping to plan the attack on Pearl Harbor. After the war he became the third Chief of Staff of the Japan Air Self-Defense Force.
Swimming at the 2011 World Aquatics Championships – Women's 100 metre backstroke
The women's 100 metre backstroke competition of the swimming events at the 2011 World Aquatics Championships were held on July 25 with the preliminary round and the semifinals and July 26 with the final.

2011 World Aquatics Championships
The 14th FINA World Championships (Chinese: 2011年世界游泳锦标赛) were held on 16–31 July 2011 in Shanghai, China at the Shanghai Oriental Sports Center. The 2011 World Championships featured five aquatics disciplines: swimming, water polo, diving, open water, and synchronized swimming.  At this championships, synchronized swimmer Natalia Ishchenko, of Russia, was the most decorated competitor winning all six gold medals of her events, at solo, duet and team routines. These championships served as qualifying stages for the 2012 Summer Olympics.

FINA announced Shanghai as the host on 24 March 2007, over other finalist Doha, Qatar.
Paradise Wood
Paradise Wood is a research woodland established by the Earth Trust (formerly Northmoor Trust) between the villages of Little Wittenham and Long Wittenham in Oxfordshire England. It has evolved to become the largest collection of hardwood forestry trials in Britain.

Planning for the wood started in 1992 and tree planting began in 1993.  The Research Woodland was originally conceived and developed by Gabriel Hemery and was established as a centre for research into the improvement of the quality and productivity hardwood trees. The ultimate aim is to create a woodland of 55 hectares in area. It contains a large number of trials supervised by the Future Trees Trust.

On the northern edge of Paradise Wood a small community woodland was planted in 2005 to commemorate the 200th anniversary of the Battle of Trafalgar.  It was named after HMS Neptune as part of a project with the Woodland Trust. It provides free public access  and contains some oak trials.

Earth Trust
Founded in 1967, Earth Trust is an environmental charity (not-for-profit organisation) which was originally known as the Northmoor Trust for Countryside Conservation. Earth Trust is the owner and manager of the largest freely accessible natural green space landscape in Oxfordshire - Wittenham Clumps: 500 hectares of woodland, farmland, wildflower meadows and wetlands. Earth Trust also care for a growing number of smaller community reserves - special places for both nature and people within urban areas and towns. These places receive 200,000+ visits each year. The organisation manages and green spaces and also operates a working farm.
Hinterau valley
The Hinterau valley (Rear Meadow Valley, German: Hinterautal) is a valley crossing the Karwendel range from east to west. The Isar has its official source in the Hinterau valley.

The valley stretches from its western end at Scharnitz to its upper eastern end called Rossloch over 14 km from west to east. Starting from Scharnitz the mountain ranges of the Northern Karwendel range and the Hinterautal-Vomp chain limit the valley to the north, just interrupted by the Karwendel valley. To the south the Gleisch-Hall chain limits the valley.

From the western side the valley first is deeply cut into by the waters of river Isar, after that part the valley follows more smoothly to the source of river Isar. After that the valley ends at an alpine bowl called Rossloch.

Isar
The Isar (pronounced [ˈiːzaʁ] ⓘ) is a river in Austria and in Bavaria, Germany. Its source is in the Karwendel mountain range of the Alps. The Isar river enters Germany near Mittenwald and flows through Krün, Wallgau, Bad Tölz, Munich, and Landshut, before reaching the Danube near Deggendorf. With 295 km length, it is among the longest rivers in Bavaria, and it is Germany's second most important tributary of the Danube.
The Pernicious Enigma
The Pernicious Enigma is the second studio album by the British doom metal band Esoteric. It was released in 1997 through Aesthetic Death Records. The Pernicious Enigma comprises two discs with a total running time of an hour and 55 minutes.

The album has received much praise since its release, and is seen as one of the band's best works. It has been cited to have helped influence the funeral doom and death-doom genres. The album would later be remastered and released as a three-disc vinyl set in 2016, limited to only 600 copies. A CD edition based on this remaster was issued in 2018.

Esoteric (band)
Esoteric is an English funeral doom metal band from Birmingham, founded in 1992. Releasing seven studio albums, and a demo, the band is widely regarded as among the first groups to develop the funeral doom style. The band has named a variety of groups as influences, such as metal bands Morbid Angel and My Dying Bride, more "trippy" artists such as Pink Floyd, Spacemen 3, and King Crimson, and the industrial and dark ambient genres.
The Referee (2010 film)
The Referee (Swedish: Rättskiparen) is a 2010 Swedish critically acclaimed, award-winning documentary film produced by Freedom From Choice AB and Sveriges Television about Swedish top football referee Martin Hansson and his controversial journey to ref at the 2010 FIFA World Cup in South Africa.

Award-winning filmmaker Mattias Löw decided to follow the former firefighter from the village of Holmsjö in Blekinge, southern Sweden for a year that turned out to be the most dramatic in Martin Hansson's life.

The film features French football player Thierry Henry, former FIFA president Sepp Blatter, Arsenal F.C. manager Arsène Wenger, former football star Pelé, Swedish Football Association, Swedish top coaches Janne Andersson and Mikael Stahre in addition to referee boss Bo Karlsson and acclaimed journalist and author Erik Niva.

Mattias Löw
Mattias Löw (born 17 September 1970) is a Swedish film director, documentary filmmaker and photographer based in Stockholm and Motala, who specializes in social issues documentaries and documentary photography. He gives lectures and workshops on the topics of storytelling and documentary filmmaking, in addition to occasional acting. His photographs from Burning Man, a week-long large-scale desert event focused on community, art, self-expression, and self-reliance, has been published and exhibited in various art galleries and museums around the world.
Iroquois Falls Storm
The Iroquois Falls Storm are a Canadian Junior "A" Hockey team based out of Iroquois Falls, Ontario, Canada.  They currently play in the Northern Ontario Junior Hockey League and are former members of the Greater Metro Junior A Hockey League.  The team was originally known as the Elliot Lake Bobcats in Elliot Lake, Ontario, until the 2014–15 season;  where they moved to Cochrane, Ontario as the Cochrane Crunch until their move to Iroquois Falls in 2023. The Storm are the third NOJHL franchise to be located in Iroquois Falls after the Iroquois Falls Jr. Eskis/Abitibi Eskimos (1999-2015) and Iroquois Falls Eskis (2015-17).

Iroquois Falls
Iroquois Falls is a town in Northern Ontario, Canada, with a population of 4,418 at the 2021 Canadian census.

The town centre lies 11 kilometres (6.8 mi) east of Highway 11 on the banks of the Abitibi River, west of Lake Abitibi. Timmins, one of the largest cities in northern Ontario, is approximately 70 kilometres (43 mi) to the southwest. The following communities are also within the municipal boundaries: Monteith, Nellie Lake, and Porquis Junction.

Iroquois Falls' primary industry was a large mill producing newsprint and commercial printing papers.  In December 2014, the owner, Resolute Forest Products, announced its permanent closure. There are also three hydro-electric dams nearby.  The Monteith Correctional Complex, a provincial prison serving a regional catchment area, is located in the community of Monteith (named for Samuel Nelson Monteith).
Shun'ichi Kase
Shun'ichi Kase (加瀬 俊一, Kase Shun'ichi, October 23, 1897– September 9, 1956) was a Japanese diplomat both during and after World War II.

Shun'ichi Kase was a secretary to Japanese Foreign Minister Yōsuke Matsuoka in 1941.  Then he was chargé d’affaires in Italy, as of 1943.  Subsequently, he served as Japanese Ambassador to Switzerland (in 1945), Japanese Ambassador to Mexico (in 1952), and Japanese Ambassador to West Germany (1953-1956).

The names Shun'ichi Kase and Toshikazu Kase are spelled in Japanese using the same characters, but are two different people. Toshikazu was a bureau chief in the foreign office in Tokyo who also served as secretary to several foreign ministers.

Toshikazu Kase
Toshikazu Kase (加瀬 俊一, Kase Toshikazu; January 12, 1903 – May 21, 2004) was a Japanese civil servant and career diplomat. During World War II he was a high-ranking Foreign Ministry official. Hideaki Kase (1936–2022) was his son and Yoko Ono is his niece.
Chestnut wattle-eye
The chestnut wattle-eye (Dyaphorophyia castanea) is a species of bird in the family Platysteiridae. It is widespread across Central Africa. Its natural habitats are subtropical or tropical moist lowland forest, subtropical or tropical swamps, and moist savanna. It is often found on cocoa farms.

Wattle-eye
Platysteiridae is a family of small, stout passerine birds of the African tropics. The family contains the wattle-eyes, batises and shrike-flycatchers. They were previously classed as a subfamily of the Old World flycatchers, Muscicapidae. These insect-eating birds are usually found in open forests or bush. They hunt by flycatching, or by taking prey from the ground like a shrike. The nest is a small, neat cup, placed low in a tree or bush.
SoHi Brands
SoHi Brands (formerly Sortis Holdings) is a private equity firm. It was established in 1995.

Businesses owned by the company include Ava Gene's, Bamboo Sushi, Cicoria, Rudy's Barbershop, Sizzle Pie, and Tusk.

Rudy's Barbershop
Rudy's Barbershop is a chain of barbershops founded in Seattle, Washington by Alex Calderwood, David Petersen and Wade Weigel in 1993, with locations primarily on the United States West Coast. Calderwood and Weigel would later go on to also co-found the Ace Hotel group in 1999. Rudy's Barbershops are known for their casual, retro-hip aesthetic and can be found at Ace Hotel locations in Seattle and New York City.