hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Luxdegalutamide
Luxdegalutamide, also known as ARV-766 and JSB462, is an investigational oral androgen receptor (AR) degrader being developed by Arvinas for the treatment of metastatic castration-resistant prostate cancer (mCRPC). It belongs to a class of drugs called proteolysis targeting chimeras (PROTACs), which are designed to selectively degrade specific proteins by hijacking the ubiquitin-proteasome system. Luxdegalutamide is a second-generation PROTAC AR degrader that has demonstrated a broader efficacy profile and better tolerability compared to its predecessor, ARV-110, in clinical settings. It has shown promise in overcoming resistance associated with certain AR mutations, including the L702H mutation, which is prevalent in up to 24% of treated mCRPC patients. As of 2024, luxdegalutamide is being evaluated in phase I/II clinical trials for prostate cancer.

Proteolysis targeting chimera
A proteolysis targeting chimera (PROTAC) is a molecule that can remove specific unwanted proteins. Rather than acting as a conventional enzyme inhibitor, a PROTAC works by inducing selective intracellular proteolysis. A heterobifunctional molecule with two active domains and a linker, PROTACs consist of two covalently linked protein-binding molecules: one capable of engaging an E3 ubiquitin ligase, and another that binds to a target protein. Recruitment of the E3 ligase to the target results in ubiquitination and subsequent degradation of the target protein via the proteasome. Because PROTACs need only to bind their targets with high selectivity (rather than inhibit the target protein's enzymatic activity), efforts are underway to retool previously ineffective inhibitor molecules as PROTACs.
MSP Estúdios
MSP Estúdios, previously known as Maurício de Sousa Produções (MSP, Mauricio de Sousa Productions), or Estúdios Mauricio de Sousa (Maurício de Sousa Studios), is the company responsible for the production of comics and cartoons, the creation and development of characters, product licensing, and all other projects related to the characters created by Mauricio de Sousa.

Mauricio de Sousa
Mauricio Araújo de Sousa (Brazilian Portuguese: [mawˈɾisju dʒi ˈsowzɐ]; born October 27, 1935), known artistically as Mauricio de Sousa or mononymously just as Mauricio, is a Brazilian cartoonist and businessman who has created over 200 characters for his popular series of children's comic books named Turma da Mônica (Monica and Friends).

At 17 years of age, he worked for a daily newspaper called Folha da Manhã as a crime reporter. In 1959, Mauricio quit that job and began his comic book career, and created Monica and Friends. Mauricio's characters were inspired by children he knew from his childhood and by his own children. His later style is slightly reminiscent of that of Osamu Tezuka, a famous Japanese manga artist and personal friend.
Mauricio's work has garnered recogniation both in his home country and abroad, which includes a number of international awards. In 2011, he was honored in the seventh edition of the Festival Internacional de Quadrinhos, at Belo Horizonte.
Sedum glaucophyllum
Sedum glaucophyllum, the cliff stonecrop, is a species of Sedum native to the Appalachian Mountains in the eastern United States from West Virginia, Maryland, Virginia and North Carolina.

Sedum glaucophyllum is a prostrate, mat-forming evergreen perennial plant forming patches up to 30–40 cm (12–15.5 in) in diameter. The leaves are glaucous green, succulent, rounded, 1–2 cm (0.5–1 in) long and wide, arranged in a dense helix on the stems. The flowers are white, 10–12 mm (0.39–0.47 in) in diameter, with four slender, pointed petals; they are produced in clusters on erect stems up to 10 cm (4 in) tall, held above the foliage.

Sedum
Sedum is a large genus of flowering plants in the family Crassulaceae, members of which are commonly known as stonecrops. The genus has been described as containing up to 600 species, subsequently reduced to 400–500. They are leaf succulents found primarily in the Northern Hemisphere, but extending into the southern hemisphere in Africa and South America. The plants vary from annual and creeping herbs to shrubs. The plants have water-storing leaves. The flowers usually have five petals, seldom four or six. There are typically twice as many stamens as petals. Various species formerly classified as Sedum are now in the segregate genera Hylotelephium and Rhodiola.

Well-known European species of Sedum are Sedum acre, Sedum album, Sedum dasyphyllum, and Sedum hispanicum.
Harry Yee
Harry K. Yee (September 26, 1918 – December 7, 2022) was an American bartender from Honolulu, Hawaii, who was credited with having helped to spread tiki culture during the mid-twentieth century, both in Hawaii and in the continental United States. He invented the Blue Hawaii cocktail, and is attributed with being the first bartender to use paper parasols and vanda orchids in tiki drinks.

Cocktail umbrella
A cocktail umbrella or paper parasol is a small umbrella made from paper, paperboard, and a toothpick. They are frequently associated with tropical drinks and Tiki bars and used as a garnish decoration. They are also used in desserts or other foods and beverages. The overall form resembles a pleated inkcap.
Pere Marquette State Park
Pere Marquette State Park is an 8,050-acre (3,260 ha) protected area in southwestern Jersey County, Illinois, United States.  It is located near the city of Grafton, Illinois, at the confluence of the Mississippi River and the Illinois River.  The park is located on Illinois Route 100, which at this location is also part of both the Great River Road and the Meeting of the Great Rivers Scenic Byway.  The park is operated and maintained by the Illinois Department of Natural Resources.  The park is also part of the Confluence Greenway and is at the northwestern end of the 21.5-mile (34.6 km) Sam Vadalabene Bike Trail.

Confluence Greenway
In 1997, with support from The McKnight Foundation, a group of non-profit organizations led by Trailnet formed a partnership to plan and implement the Confluence Greenway. The Confluence Greenway was planned as a 200-square-mile (520 km2) system of parks, conservation and recreation areas located in the St. Louis, Missouri metropolitan area. Various parks, trails, and attractions are located along forty miles of both the Missouri and Illinois banks of the Mississippi River and Missouri River.
Enkhbatyn Badar-Uugan
Enkhbatyn Badar-Uugan (Mongolian: Энхбатын Бадар-Ууган; born 3 June 1985, in Ulaanbaatar) is a retired boxer from Mongolia who became the first Olympic boxing champion from his country when he won the gold medal in the Bantamweight (-54 kg) division at the 2008 Summer Olympics. He was the second Mongolian to win an Olympic gold in any sport, with judoka Naidangiin Tüvshinbayar winning the first only a few days earlier.

Bantamweight
Bantamweight is a weight class in combat sports and weightlifting. For boxing, the range is above 115 lb (52.2 kg) and up to 118 lb (53.5 kg). In kickboxing, a bantamweight fighter generally weighs between 53 and 55 kilograms (117 and 121 lb). In MMA, bantamweight is 126–135 lb (57.2–61.2 kg).

The name for the class is derived from bantam chickens. Brazilian jiu-jitsu has an equivalent Rooster weight.
Ceranova
Ceranova is a comune (municipality) in the Province of Pavia in the Italian region Lombardy, located about 25 km south of Milan and about 11 km northeast of Pavia.

Ceranova borders the following municipalities: Bornasco, Lardirago, Marzano, Vidigulfo.

Marzano, Pavia
Marzano is a comune (municipality) in the Province of Pavia in the Italian region Lombardy, located about 25 km southeast of Milan and about 14 km northeast of Pavia.

Marzano borders the following municipalities: Ceranova, Lardirago, Roncaro, Torre d'Arese, Torrevecchia Pia, Valera Fratta, Vidigulfo and Vistarino.
Maine mac Cerbaill
Maine mac Cerbaill (died 538) was a king of Uisnech in Mide of the Ui Neill. He was the son of  Fergus Cerrbél, grandson of Conall Cremthainne (died 480) and brother of the high king Diarmait mac Cerbaill (died 565). He ruled from 520 to 538.

Maine was defeated and slain at the Battle of Claenloch (near Kinelea, Co.Galway) by Goibnenn mac Conaill of the Ui Fiachrach Aidhne. Maine was attempting to secure the hostages of the Uí Maine. This battle marked the division of the Ui Maine subject to Connacht and the Cenél Maine of Tethba, subject to the Southern Ui Neill. It is also possible this battle took place at Clea Lake, near Keady in Armagh, which points to the origins of the family of Diarmait mac Cerbaill in the territory north of the Boyne and Blackwater.

Goibnenn mac Conaill
Goibnenn mac Conaill (flourished 537) was the first king of the Ui Fiachrach Aidhne mentioned in the annals. He was the great-grandson of the high king Nath Í (died 445).

In 537 he defeated the King of Uisnech, Maine mac Cerbaill, of the Southern Ui Neill at the Battle of Claenloch (near Kinelea, Co. Galway) and Maine was slain. Maine was attempting to secure the hostages of the Uí Maine. This battle marked the division of the Ui Maine subject to Connacht and the Cenél Maine of Tethba, subject to the Southern Ui Neill. This victory would lead to the domination of the kingship of Connacht by the Ui Fiachrach Aidne in the 7th century.
Yangon Region
Yangon Region (Burmese: ရန်ကုန်တိုင်းဒေသကြီး, MLCTS: rankun tuing desa. kri:, pronounced [jàɰ̃ɡòʊɰ̃ táɪɰ̃ dèθa̰ dʑí]; formerly Rangoon Division and Yangon Division) is an administrative region of Myanmar. Located in central Myanmar, the region is bordered by Bago Region to the north and east, the Gulf of Martaban to the south, and Ayeyarwady Region to the west. Yangon Region is dominated by its capital city of Yangon, the former national capital and the largest city in the country. Other important cities are Thanlyin and Twante. The division is the most developed region of the country and the main international gateway. The division measures 10,170 km2 (3,930 sq mi).

Bamar people
The Bamar people (Burmese: ဗမာလူမျိုး, ba. ma lu myui: IPA: [bə.mà lù mjó]; also known as Burmese people or Burmans) are a Sino-Tibetan-speaking ethnic group native to Myanmar (formerly known as Burma). With an estimated population of around 35 million people, they are the largest ethnic group in Myanmar, accounting for 68.78% of the country's total population. The geographic homeland of the Bamar is the Irrawaddy River basin. The Bamar speak the Burmese language which serves as the national language and lingua franca of Myanmar.
North African Cup of Champions
The North African Cup of Champions was a tournament designed by the Union of North African Football (UNAF) that puts together the winners of the domestic leagues around North Africa. The tournament contains representatives from Algeria, Libya, Morocco and Tunisia.

UNAF Club Cup
The UNAF Club Cup (Arabic: كأس إتحاد شمال إفريقيا للأندية) is a tournament designed by the Union of North African Football Federations (UNAF) that puts together the top three best finishers of the domestic leagues and the two finalists of the domestic cups around North Africa. The tournament has representatives from Algeria, Egypt, Libya, Morocco and Tunisia.
Parc de la Ciutadella
The Parc de la Ciutadella (Catalan pronunciation: [ˈpaɾɡ də lə siwtəˈðeʎə]; lit. 'Citadel Park'; Spanish: Parque de la Ciudadela; Spanish pronunciation: [ˈpaɾke ðe la θjuðaˈðela]) is a park on the northeastern edge of Ciutat Vella, Barcelona, Catalonia, Spain. For decades following its creation in the mid-19th century, this park was the city's only green space. The 31-hectare (77 acres) grounds include the city zoo (once home to the albino gorilla Snowflake, who died in 2003), the Palau del Parlament de Catalunya, a small lake, museums, and a large fountain designed by Josep Fontserè (with possible contributions by the young Antoni Gaudí).

As the location of the Parliament of Catalonia, the tensions in 2018 and 2019 regarding Catalan independence regularly led to the police closure of the park to public access to prevent crowds forming near to the official buildings.

1888 Barcelona Universal Exposition
The 1888 Barcelona Universal Exposition (in Catalan: Exposició Universal de Barcelona and Exposición Universal de Barcelona in Spanish) was Spain's first International World's Fair and ran from 8 April to 9 December 1888. The second one in Barcelona was held in 1929.
Ground Master 200 Multi Mission
The Ground Master 200 Multi-Mission (GM200 MM) is a family of medium-range ground-based radars developed and manufactured by Thales.

Benefiting from the technology of the land-based Ground Master 200 and naval NS100/200 radar systems, the GM200 MM family consists of the GM200 MM/A, designed and manufactured in France, on the one hand; and the GM200 MM/C on the other, developed by the company's Dutch subsidiary, Thales Nederland, for, and in consultation with, the Royal Netherlands Army (RNLA). The two radars feature 4D Active Electronically Scanned Array (AESA) technology, a ‘dual-axis multi-beam’ technology providing flexibility in both elevation and bearing.

The first delivery of the GM200 MM/C to the RNLA took place on 14 February 2024.

Thales Group
Thales S.A., trading as Thales Group (French pronunciation: [talɛs]), is a French multinational aerospace and defence corporation specialising in electronics.

It designs, develops and manufactures a wide variety of aerospace and military systems, devices and equipment but also operates in the cybersecurity and formerly civil ground transportation sectors. The company is headquartered in Paris' business district, La Défense, and its stock is listed on Euronext Paris.

Founded as Thomson-CSF in 1968, the group was rebranded Thales in 2000 due to the company's desire to simplify and improve the group's brand.

Thales is partially owned by the French state and operates in more than 68 countries. In 2023, the company generated €18,42 billion in revenue and was the 17th largest defence contractor in the world, with 53% of its total revenue generated from its military activities.
Te Kawa
Te Kawa is a rural community in the Ōtorohanga District and Waikato region of New Zealand's North Island. It lies just to the south of the volcanic hills of Kakepuku and Te Kawa. Until the swamp was drained in the 1900s, Te Kawa was well known for its eels.

Te Kawa railway station, a station on the North Island Main Trunk, was located in the area. It operated from 9 March 1887 and closed 17 October 1971.

A post office was open by 1909 and a dairy factory and a school existed in 1913. Te Kawa Bridge over the Waipā opened in 1915. A town hall opened in 1928.

Te Whakaaro Kotahi Marae in Te Kawa is a meeting ground of the Ngāti Maniapoto hapū of Te Kanawa. It includes a small building.

Ōtorohanga District
Ōtorohanga District is a territorial authority in the King Country area and Waikato region of the North Island of New Zealand. It is a mostly rural area, with Ōtorohanga town being by far the biggest urban area, with a population nearing 3,000. The District was called Otorohanga County from 1971 to 1979.
Palazzo Corner della Regina
Palazzo Corner della Regina, commonly known as Ca' Corner della Regina, is a Baroque-style palace in the Sestiere Santa Croce of the city of Venice, Italy. In the English language, the title conforms with Palace of the Queen from the "Corner (or Cornaro) Family"; it is so named because Caterina Cornaro, who became Queen of Cyprus by marriage, was born to this family and at this site in 1454. The palace is located on the Grand Canal, near Ca' Pesaro, and between Ca' Favretto and Palazzo Correggio. The opposite structure is Palazzo Contarini Pisani.

Palazzo Contarini Pisani
Palazzo Contarini Pisani is a palace in Venice, located in the Cannaregio district, overlooking the left side of the Grand Canal, between Palazzo Boldù and Casa Levi Morenos, in front of Ca' Corner della Regina.
1947 European Rowing Championships
The 1947 European Rowing Championships were rowing championships held on the Rotsee in the Swiss city of Lucerne. The competition was for men only, they competed in all seven Olympic boat classes (M1x, M2x, M2-, M2+, M4-, M4+, M8+), and 15 nations participated. It was the first European Rowing Championships held after World War II, and it was the second time that the regatta was held on the Rotsee; the previous regatta was in 1934.

Rotsee
The Rotsee (Swiss Standard German pronunciation: [ˈroːtˌzeː]; previously known as Rootsee) is a natural rowing lake on the northern edge of Lucerne, Switzerland. It is regarded as one of the best rowing venues in the world.
Henry Spalding (architect)
Henry Spalding (4 Sept 1838 – 25 Jun 1910) was a British architect.

Spalding was an assistant for William Gilbee Habershon and Edward Habershon from 1857 to 1863. He was in partnership with Samuel Knight (architect) and then went on to establish his own practice with Edward Haberson and later went into partnership with Patrick Auld, Alfred William Stephens Cross and his son Reginald Henry Spalding.

His buildings include Dulwich Public Baths, Camberwell Public Baths and Belle Vue House, Sudbury, Suffolk

Alfred Cross
Alfred William Stephens Cross (1858–1932) was a British architect.

From 1889 to 1899 he was in partnership with Henry Spalding as Spalding and Cross, taking part in many competitions for building design. Cross and his son (Kenneth Mervyn Baskerville Cross, 1890–1968) became specialised in designs for public baths.
Susan Bayly
Susan Bayly is Professor Emerita of Historical Anthropology in the Cambridge University Department of Social Anthropology and a Life Fellow of Christ's College, Cambridge. She is a former editor of the Journal of the Royal Anthropological Institute.

Her research interests include the South Asian caste system. She was married to fellow Cambridge historian, Christopher Bayly, until his death in 2015.

To mark her retirement, and her scholarly works, former students and colleagues published a collected volume of essays in her honour 2023.

Christopher Bayly
Sir Christopher Alan Bayly, FBA, FRSL (18 May 1945 – 18 April 2015) was a British historian specialising in British Imperial, Indian and global history. From 1992 to 2013, he was Vere Harmsworth Professor of Imperial and Naval History at the University of Cambridge.
Piebald Horde
The Piebald Horde (Russian: Пегая Орда) is the Russian term for a confederation of Selkup and Ket tribes in the Ob and Tom river basins which existed in the 16th century, in what is called the Narym region. It was the eastern neighbor and ally of the Khanate of Sibir. As Russian encroachment became a bigger threat, Piebald found itself in conflict with some of the Ugrian Khanty principalities that had allied itself with the Grand Duchy of Moscow, and later the Tsardom of Russia, namely the Principality of Kod.

Principality of Kod
The Principality of Kod (Cyrillic: Кодское княжество), or the Principality of Koda (Кода), was a Khanty principality located in north Western Siberia from the 15th to 17th century. It was located on both banks of the Ob River and along the river tributaries of Kazym and Irtysh, occupying an area approximately now the Oktyabrsky District of the Khanty-Mansi Autonomous Okrug. The rulers of Kod, the House of Alachev, had in their possession various fortified towns along the banks of the Ob, the largest of which being the capital of Shorkar (lit. "city on a stream"), later Alachev. Kod was generally allies of the Grand Duchy of Moscow, and later the Tsardom of Russia, engaging in conflicts with other Yugra states like the Principality of Pelym, though occasionally also siding with enemies of Moscow, like Kuchum Khan of the Sibir Khanate or rebel Ivan Bolotnikov. The principality was ultimately annexed into the expanding Russian state in 1643.
2018 NIRSA National Soccer Championship
The 2018 NIRSA national soccer championship was the 25th NIRSA National Soccer Championships, the annual national championships for United States-based, collegiate club soccer teams organized by NIRSA. It took place at Foley Tourism Complex, in Foley, Alabama from Thursday, November 29 to Saturday, December 1, 2018.

Weather cancelled the initial tournament prematurely, however a continuation was held for three of the four divisions, with the only division to not have a continuation, the men's open division, naming both finalists as champions.

NIRSA National Soccer Championships
The NIRSA National Soccer Championships is an annual collegiate club competition organized by the National Intramural and Recreational Sports Association (NIRSA), deciding the competition winners through a round robin group stage to qualify for a single-elimination knockout format.

The tournament is unique because it is limited to teams representing a university on a non-varsity level. Due to collegiate clubs receiving little to no funding from the university they represent, their ability to travel is limited and why the tournament takes place over a single weekend; typically in late November to early December.
Distributive property
In mathematics, the distributive property of binary operations is a generalization of the distributive law, which asserts that the equality

is always true in elementary algebra.
For example, in elementary arithmetic, one has

Therefore, one would say that multiplication distributes over addition.

This basic property of numbers is part of the definition of most algebraic structures that have two operations called addition and multiplication, such as complex numbers, polynomials, matrices, rings, and fields. It is also encountered in Boolean algebra and mathematical logic, where each of the logical and (denoted ) and the logical or (denoted ) distributes over the other.

Distributivity (order theory)
In the mathematical area of order theory, there are various notions of the common concept of distributivity, applied to the formation of suprema and infima. Most of these apply to partially ordered sets that are at least lattices, but the concept can in fact reasonably be generalized to semilattices as well.
University Hall (Lincoln, Illinois)
University Hall is a building on the campus of Lincoln College in Lincoln. Built from 1865 to 1866, the building was the first constructed on the campus of the college, then known as Lincoln University. The college was founded by the Cumberland Presbyterian Church and was at the time one of the few religiously affiliated schools in the North. University Hall was designed in a Tuscan-influenced Italianate style and features a four-sided cupola and a cornice with dentils and corbels. Until the college's closure in May 2022, the building housed the school's administrative offices.  Since the closure, the building houses the liquidation office.

University Hall was added to the National Register of Historic Places on April 24, 1973.

Lincoln College (Illinois)
Lincoln College was a private college in Lincoln, Illinois.  The college offered associate, bachelor's, and master's programs. It maintained an extension site in Normal, Illinois that provided adults with Accelerated Bridge to Education bachelor's degree programs. The college closed on May 13, 2022.
Lienen
Lienen (German pronunciation: [ˈliːnən]; Westphalian: Linen) is a municipality in the district of Steinfurt, in North Rhine-Westphalia, Germany. It is situated approximately 15 km south-east of Osnabrück and 30 km north-east of Münster.

Lienen is a sister city with Saint Marys, Ohio in the United States. Lienen's neighboring municipalities, Ladbergen and Lengerich, are sister cities with Saint Marys' neighbors New Knoxville and Wapakoneta, respectively.

Lengerich, Westphalia
Lengerich (German pronunciation: [ˈlɛŋəʁɪç] ⓘ; Westphalian: Lengerke) is a town in the district of Steinfurt, in North Rhine-Westphalia, Germany. It is situated on the southern slope of the Teutoburg Forest, approx. 15 km south-west of Osnabrück and 30 km north-east of Münster.