hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Carbonic anhydrase inhibitor
Carbonic anhydrase inhibitors are a class of pharmaceuticals that suppress  the activity of carbonic anhydrase. Their clinical use has been established as anti-glaucoma agents, diuretics, antiepileptics, in the management of mountain sickness, gastric and duodenal ulcers, idiopathic intracranial hypertension, neurological disorders, or osteoporosis.

Members of carbonic anhydrase inhibitor group of medications include: acetazolamide, dorzolamide, methazolamide, brinzolamide, dichlorphenamide.

Dorzolamide
Dorzolamide, sold under the brand name Trusopt among others, is a medication used to treat high pressure inside the eye, including in cases of glaucoma. It is used as an eye drop. Effects begin within three hours and last for at least eight hours. It is also available as the combination dorzolamide/timolol.

Common side effects include eye discomfort, eye redness, taste changes, and blurry vision. Serious side effects include Steven Johnson syndrome. Those allergic to sulfonamides may be allergic to dorzolamide. Use is not recommended in pregnancy or breastfeeding. It is a carbonic anhydrase inhibitor and works by decreasing the production of aqueous humor.

Dorzolamide was approved for medical use in the United States in 1994. It is available as a generic medication. In 2023, it was the 190th most commonly prescribed medication in the United States, with more than 2 million prescriptions.
Hele, Devon
Hele is a village in Devon, England, lying about one mile (1.6 km) SSW of Bradninch and 10 miles (16 km) NNE of Exeter, on the River Culm.

The village is home to a paper mill once belonging to the company Wiggins Teape, now part of the multinational company Purico Group. The Devon Valley Mill produces sausage casing paper and teabag paper under the "Crompton Paper" brand name.

The mill site was originally that of a flour mill which was converted to a paper mill in 1762. It was here that John Dewdney produced the first glazed writing paper in England in the 1840s. He was also famously called upon to supply the paper for the catalogues of the Great Exhibition in 1851.

The nearby railway station, now closed, used to serve Hele and Bradninch.

Bradninch
Bradninch is a small town, civil parish and manor in Devon, England, lying about 3 miles (5 km) south of Cullompton. Much of the surrounding farmland belongs to the Duchy of Cornwall. There is an electoral ward with the same name, which since May 2023 comprises the entire parish. The population was 2,165 in 2021.

In 2012, in research of 2,400 postcodes in England and Wales which took into account 60 separate factors of interest to young families, Bradninch was found to be the fifteenth most family friendly location in the country.

The town is twinned with Landunvez in Brittany and Downingtown, Pennsylvania.
Coat of arms of Melilla
The coat of arms of Melilla is that of the Ducal House of Medina Sidonia, whose titular funded the military operation that seized Melilla in 1497.

The crown is topped by a turret, with a male figure throwing a dagger (Guzmán el Bueno, ancestor of the first duke) in chief. The top part of the coat of arms reads Præferre Patriam Liberis Parentem Decet (Latin: "It is seemly for a parent to put his fatherland before his children"), also a nod to the Guzmán el Bueno's role during the 1296 defence of Tarifa on behalf of Sancho IV of Castile. The supporters are the Pillars of Hercules and read Non Plus Ultra (Latin: "Nothing further beyond").

It is the central device of the flag of Melilla, which consists of a pale blue background. The flag was adopted on 13 March 1995 when Melilla became an autonomous city of Spain.

Pillars of Hercules
The Pillars of Hercules are the promontories that flank the entrance to the Strait of Gibraltar. The northern Pillar, Calpe Mons, is the Rock of Gibraltar. A corresponding North African peak not being predominant, the identity of the southern Pillar, Abila Mons, has been disputed throughout history, with the two most likely candidates being Monte Hacho in Ceuta and Jebel Musa in Morocco.  The term was applied in antiquity: Pliny the Elder included the Pillars of Hercules in his Naturalis historia (Book III:3).
Fusarium venenatum
Fusarium venenatum is a microfungus of the genus Fusarium that has a high protein content. One of its strains is used commercially for the production of the single cell protein mycoprotein Quorn.

Fusarium venenatum was discovered growing in soil in Buckinghamshire in the United Kingdom, in 1967 by ICI as part of the effort during the 1960s to find alternative sources of food to fill the protein gap caused by the growing world population. It was originally misidentified as Fusarium graminearum.

The strain Fusarium venenatum A3/5 (IMI 145425, ATCC PTA-2684) was developed commercially by an ICI and Rank Hovis McDougall joint venture to derive a mycoprotein used as a food. Because the hyphae of the fungus are similar in length and width to animal muscle fibres the mycoprotein is used as an alternative to meat and is marketed as Quorn. It is also suitable as a substitute for fat in dairy products and a substitute for cereal in breakfast cereals and snacks.

Fusarium
Fusarium (/fjuˈzɛəriəm/; Audio:ⓘ) is a large genus of filamentous fungi, part of a group often referred to as hyphomycetes, widely distributed in soil and associated with plants. The name of Fusarium comes from Latin fusus, meaning a spindle. Most species in Genus Fusarium are harmless saprobes found in relative abundance in the soil microbial community, and some exist as commensal members of the skin microbiome.

Some species produce mycotoxins in cereal crops that can affect human and animal health if they enter the food chain; the main toxins produced by Fusarium species are the fumonisin and trichothecene families, and zearalenone. Despite most species being harmless, some Fusarium species and subspecific groups are among the most important fungal pathogens of plants and animals.
Characodon
Characodon is a genus of splitfins endemic to north–central Mexico. Two of the species are highly threatened and restricted to pools, ponds and springs in the upper San Pedro Mezquital River basin in Durango. The third species, C. garmani, was restricted to springs near Parras in Coahuila, but it became extinct when they dried out.

Goodeidae
Goodeidae is  a family  of teleost fish endemic to Mexico and some areas of the United States. Many species are known as splitfins. This family contains about 50 species within 18 genera. The family is named after ichthyologist George Brown Goode (1851–1896).

The earliest fossil goodeid is Tapatia, a goodeine from the middle Miocene of Mexico. The earliest fossil empetrichthyine is Empetrichthys erdisi from the Miocene or Pliocene of California.
Gambit
A gambit (from Italian gambetto, the act of tripping someone with the leg to make them fall) is a chess opening in which a player sacrifices material with the aim of achieving a subsequent positional advantage.

Sacrifice (chess)
In chess, a sacrifice is a move that gives up a piece with the objective of gaining tactical or positional compensation in other forms. A sacrifice could also be a deliberate exchange of a chess piece of higher value for an opponent's piece of lower value.

Any chess piece excluding the king may be sacrificed. Because players usually try to hold on to their own pieces, offering a sacrifice can come as an unpleasant surprise to one's opponent, putting them off balance and causing them to waste precious time trying to calculate whether the sacrifice is sound or not, and whether to accept it. Sacrificing one's queen (the most valuable piece), or a string of pieces, adds to the surprise, and such games can be awarded brilliancy prizes.
Fort Sill
Fort Sill is a major United States Army post north of Lawton, Oklahoma, approximately 85 miles (137 km) southwest of Oklahoma City, established in 1869 during the Indian Wars. It covers almost 94,000 acres (38,000 ha) in southwestern Oklahoma and serves as headquarters of the U.S. Army Fires Center of Excellence. The installation is a Basic Combat Training facility, training over 20,000 personnel annually in field artillery, air defense artillery, and electronic warfare.

Fort Sill has participated in every major U.S. conflict since its founding, evolving from a frontier cavalry outpost to a modern training hub. It houses key units including the United States Army Field Artillery School, 75th Field Artillery Brigade (United States), and the 31st Air Defense Artillery Brigade (United States). The post also supports a United States Marine Corps detachment for joint artillery training.

Fort Richardson (Texas)
Fort Richardson was a United States Army installation located in present-day Jacksboro, Texas.  Named in honor of Union General Israel B. Richardson, who died in the Battle of Antietam during the American Civil War, it was active from 1867 to 1878. Today, the site, with a few surviving buildings, is called Fort Richardson State Park, Historic Site, and Lost Creek Reservoir State Trailway.   It was designated a National Historic Landmark in 1963 for its role in securing the state's northern frontier in the post-Civil War era.
Elie Azagury
Elie Azagury (Arabic: إيلي الزاقوري; 1918-2009) was an influential Moroccan architect and director of the Groupe des Architectes Modernes Marocains (GAMMA) after Moroccan independence in 1956. He is considered the first Moroccan modernist architect, with works in cities such as Casablanca, Tangier, and Agadir. Azagury was also a controversial and outspoken Communist, and was active designing cités, or social housing projects made up of modular units, in places like Hay Hassani in Casablanca. These projects combined elements of modern and vernacular architecture, taking local culture and lifestyles into account.

Jean-François Zevaco
Jean-François Zevaco (Arabic: جان فرنسوا زيفاكو; 8 August 1916 – 2003) was a French-Moroccan architect born in Casablanca. He is considered an emblematic figure of the modernist architectural movement in Morocco and in Africa, and his legacy is important in terms of the number of constructions built across Morocco, the diversity of his works, and their international aura.

After his finishing his studies at the École nationale supérieure des Beaux-Arts in Paris and Marseille in 1945, he established a private practice in Morocco and started a career spanning from 1947 to 1999. He marked the architecture of the second half of the 20th century with a resolutely modern work in intense dialogue with the country, the people, and the landscapes surrounding him.
General Emilio Aguinaldo, Cavite
General Emilio Aguinaldo, officially the Municipality of General Emilio Aguinaldo (Tagalog: Bayan ng Heneral Emilio Aguinaldo), is a municipality in the province of Cavite, Philippines. According to the 2024 census, it has a population of 24,264 people.

Formerly known and still commonly referred to as Bailen, the municipality was renamed General Emilio Aguinaldo in honor of Emilio Aguinaldo, the first president of the Philippines and a native of Cavite.

Maragondon
Maragondon, officially the Municipality of Maragondon (Tagalog: Bayan ng Maragondon), is a municipality in the province of Cavite, Philippines. According to the 2024 census, it has a population of 41,977 people.

The town is famous for its bamboo crafts, Mounts Palay-Palay–Mataas-na-Gulod Protected Landscape which includes Mount Pico de Loro, and various ancestral houses and structures important to Philippine history and culture such as Maragondon Church and the execution site and trial house of national hero Andres Bonifacio.
Ducktown, Tennessee
Ducktown  (Cherokee: ᎦᏬᏅᏱ, romanized: Gawonvyi) is a city in Polk County, Tennessee, United States. The population was 461 at the 2020 census and 475 at the 2010 census. It is included in the Cleveland, Tennessee metropolitan area.

Polk County, Tennessee
Polk County is a county located in the southeastern corner of the U.S. state of Tennessee. As of the 2020 United States census, its population was 17,544. Its county seat is Benton. The county was created on November 28, 1839, from parts of Bradley and McMinn counties, after final removal of most Cherokee from the region that year. The county was named after then-governor (and future president) James K. Polk. Polk County is included in the Cleveland, Tennessee Metropolitan Area Statistical Area, which is also included in the Chattanooga–Cleveland–Dalton, TN–GA–AL Combined Statistical Area.
Derrick Trench
Major Derrick le Poer Trench DSO MC (25 May 1882 – 27 August 1917) was a British Army officer and recipient of the Military Cross.

Trench was born in 1882, the son of Colonel Stewart Trench. He was educated at Bloxham School in Oxfordshire and the Royal Military Academy, Woolwich.

Trench was commissioned into the Royal Artillery in 1900, being promoted to captain in 1912. He served with the Guards Division Artillery during the First World War and was promoted to major in 1915. He was awarded the Military Cross the same year. Trench was mentioned in dispatches four times during the war, on 22 June 1915, 1 January and 15 June 1916, and 11 December 1917. He was made a Companion of the Distinguished Service Order in 1917. He was killed, alongside Brigadier-General Malcolm Peake, by a German shell on 27 August 1917.

Bloxham School
Bloxham School, also called All Saints' School, is a private co-educational day and boarding school of the British public school tradition, located in the village of Bloxham, three miles (5 km) from the town of Banbury in Oxfordshire, England. The present school was founded in 1860 by Philip Reginald Egerton and has since become a member of the Woodard Corporation. The current headmaster is Paul Sanderson, who took over from Mark Allbrook in 2013. The school has approximately 560 pupils with a maximum current capacity of 600.

The school is affiliated with Woodard Schools, as only the governors/governing body is fully responsible for the school's performance, but hold responsibility to the Woodard Board. On Woodard Schools website it is listed under "Woodard Incorporated Schools (independent)".

Founded as a school of the Oxford Movement, Bloxham is a member of the Headmasters' and Headmistresses' Conference.
Night sweats
Night sweats or nocturnal hyperhydrosis is the repeated occurrence of excessive sweating during sleep. The person may or may not also perspire excessively while awake. Hot flashes and night sweats are vasomotor symptoms, and the most common symptoms of menopause.

One of the most common causes of night sweats in women over 40 is the hormonal changes related to menopause and perimenopause. This is a very common occurrence during the menopausal transition years. Over 80% of women experience hot flashes, which may include excessive sweating, during menopause.

Night sweats range from being relatively harmless to a sign of underlying disease. Night sweats may happen because the sleep environment is too warm, either because the bedroom is unusually hot or because there are too many covers on the bed.  Night sweats have been associated with a long list of clinical conditions. However, there is very little evidence that supports clinical recommendations for this condition.

Hot flash
Hot flash, also known as hot flush is a vasomotor symptom, often caused by the changing hormone levels that are characteristic of menopause. It is typically experienced as a feeling of intense heat with sweating and rapid heartbeat, and may typically last from two to 30 minutes for each occurrence. Hot flashes are the most commonly recognized menopausal symptom. Longer duration vasomotor symptoms are more often called hot flushes.
Blakely Auto Works
Blakely Auto Works (also called Bernardi Auto Works in later years) was a manufacturer of automobiles and of kit cars, working from premises located in a series of US midwest communities, including Princeton, Wisconsin, in the 1970s and 1980s. Blakely produced several kit car models, the Bantam, Bearcat, and Bernardi.

Kit car
A kit car is an automobile available as a set of parts that a manufacturer sells and the buyer then assembles into a functioning car. Usually, many of the major mechanical systems such as the engine and transmission are sourced from donor vehicles or purchased new from other vendors. Kits vary in completeness, consisting of as little as a book of plans, or as much as a complete set with all components to assemble into a fully operational vehicle such as those from Caterham.
Curry, Walker County, Alabama
Curry is an unincorporated community in north-central Walker County Alabama, United States. It is the closest community to the Lewis Smith Lake dam. Curry is served by Alabama State Route 257, which is simply known as Curry Highway by locals.

Walker County, Alabama
Walker County is a county located in the central portion of the U.S. state of Alabama. As of the 2020 census, the population was 65,342. Its county seat is Jasper. Its name is in honor of John Williams Walker, the first U.S. senator elected from Alabama.

Walker County comprises the entirety of the Jasper, AL Micropolitan Statistical Area.
Maroua Kharbouch
Maroua Kharbouch (born 20 September 1990) is a Gibraltarian model and beauty pageant titleholder who was crowned Miss Gibraltar 2013 and was named as the people's choice at Miss World 2013 in Bali, Indonesia where Megan Young of the Philippines won the pageant, earning her a place in the Top 6 finalists. She was the first Gibraltarian of Moroccan descent to be crowned Miss Gibraltar and the second Gibraltarian finalist at a Miss World beauty pageant.

Gibraltarians
Gibraltarians (Spanish: gibraltareños, colloquially: llanitos) are a sub-national group who live in Gibraltar, a British overseas territory situated near the southern tip of the Iberian Peninsula, close to Spain, at the entrance to the Mediterranean Sea. Gibraltarians hold British citizenship.
Akita Asahi Broadcasting
Akita Asahi Broadcasting Co., Ltd. (秋田朝日放送株式会社, Akita Asahi Hōsō Kabushiki-gaisha), also known as AAB, is a Japanese terrestrial television station affiliated with the All-Nippon News Network, covering all of Akita Prefecture. Their headquarters are located in Akita, its capital with its main transmitter is located at Omoriyama Park, in the city of Akita.

All-Nippon News Network
All-Nippon News Network (ANN; Japanese: オールニッポンニュース・ネットワーク, romanized: Ōrunippon Nyūsu Nettowāku) is a Japanese commercial television network run by TV Asahi Corporation (TV Asahi) in Tokyo, a subsidiary of the TV Asahi Holdings Corporation, which is controlled by The Asahi Shimbun Company. The network's responsibilities include the syndication of national television news bulletins to its regional affiliates, and the news exchange between the stations. Its affiliate stations also broadcast non-news programs originating from TV Asahi. Founded on 1 January 1970,: 161–163  and formalised on 1 April 1974, ANN is made up of 26 affiliates, including two stations that are double- or triple-affiliated with rival networks.

Between 1989 and 2013, it also operated the 24-hour satellite and cable news channel Asahi Newstar.
Squantum Yacht Club
The Squantum Yacht Club (SYC) was founded in 1890 by like-minded individuals in order to help promote sailing and boatsmanship on Boston's south shore.  Located on Quincy Bay at Wollaston Beach, the club is a cooperatively owned venture by both sailors and power boaters, each member contributing both money and time to maintain the ideals of its founders, the club house and its docks.  The SYC also hosts the annual Lipton Cup Regatta, each July in which eastern Massachusetts boating clubs and sailing programs compete in a number of races in Quincy Bay.

Quincy Bay
Quincy Bay is the largest of the three small bays of southern Boston Harbor, part of Massachusetts Bay and forming much of the shoreline of the city of Quincy, Massachusetts. Locally in the Wollaston neighborhood of Quincy it is known as Wollaston Bay. The bay is home to Moon Island, Long Island, and Hangman Island.

Quincy Bay extends from Squantum and Dorchester Bay in the northwest to Hough's Neck and Hingham Bay in the east. Its southwestern shore is Wollaston Beach. The Squantum Yacht Club and the Wollaston Yacht Club are on Quincy Bay along Wollaston Beach. Quincy Shore Drive, one of the Massachusetts Department of Conservation and Recreation parkways in the Greater Boston area, travels 2.1 miles (3.4 km) along Quincy Bay, offering panoramic views of the Boston Harbor Islands and the Boston skyline.
Nitrospira inopinata
Nitrospira inopinata is a bacterium from the phylum Nitrospirota. This phylum contains nitrite-oxidizing bacteria playing role in nitrification. However N. inopinata was shown to perform complete ammonia oxidation to nitrate thus being the first comammox bacterium to be discovered.

N. inopinata was cultivated in enrichment culture. Initial inoculum was obtained in 2011 from microbial biofilm growing on metal surface of the pipe covered by hot water (56 °C, pH 7.5), which was raised from 1 200m deep oil exploration well. The well was located in Aushiger, North Caucasus, Russia. The growth in pure culture was achieved in 2017.

Genome of N. inopinata was released in 2015 represented by 3.3 Mbp, with 3 116 genes and 59.2% GC content. NCBI accession number is LN885086.

Nitrification
Nitrification is the biological oxidation of ammonia to nitrate via the intermediary nitrite. Nitrification is an important step in the nitrogen cycle in soil. The process of complete nitrification may occur through separate organisms or entirely within one organism, as in comammox bacteria. The transformation of ammonia to nitrite is usually the rate limiting step of nitrification. Nitrification is an aerobic process performed by small groups of autotrophic bacteria and archaea.
Brenles
Brenles  is a former municipality in the district Broye-Vully in the canton of Vaud in Switzerland.  In 2017 the former municipalities of Brenles, Chesalles-sur-Moudon, Cremin, Forel-sur-Lucens and Sarzens merged into the municipality of Lucens.

Sarzens
Sarzens  is a former municipality in the district Broye-Vully in the canton of Vaud in Switzerland.  In 2017 the former municipalities of Sarzens, Brenles, Chesalles-sur-Moudon, Cremin, Forel-sur-Lucens merged into the municipality of Lucens.
And in the End...
"And in the End..." is the series finale of the American medical drama television series ER. The two-hour episode, which serves as the 22nd episode of the fifteenth season and the 331st episode overall, was written by John Wells and directed by Rod Holcomb and aired on NBC on April 2, 2009. It was preceded by a one-hour retrospective special.

Samantha Taggart
Samantha "Sam" Taggart is a fictional character on the NBC television drama ER. She is played by actress Linda Cardellini. Linda Cardellini's addition into the main cast opening credits was in 2003, in the fifth episode of season 10.
Well of Dina Nath
The Well of Dina Nath (Punjabi: دِینا ناتھ دا کُھوہ , Urdu: دینا ناتھ کا کنواں) was intended to be a water well in the Wazir Khan Chowk in Lahore, Punjab, Pakistan. The well's construction in the 19th century by a Sikh nobleman sparked controversy, given its location in the immediate vicinity of the Wazir Khan Mosque.

Wazir Khan Mosque
The Wazir Khan Mosque is a 17th-century Mughal mosque located in the city of Lahore, Punjab, Pakistan. The mosque was commissioned by the then governor of Punjab, Wazir Khan, during the reign of the Mughal Emperor Shah Jahan as a part of an ensemble of buildings that also included the nearby Shahi Hammam baths. Construction of the Mosque began in 1634, and was completed in 1641.

Considered to be the most ornately decorated Mughal-era mosque, Wazir Khan Mosque is noted for its intricate faience tile work known as kashi-kari, as well as its interior surfaces that are almost entirely embellished with elaborate  frescoes. It is on the UNESCO World Heritage Tentative List.