hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Tyrosine kinase
A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell. It functions as an "on" or "off" switch in many cellular functions.

Tyrosine kinases belong to a larger class of enzymes known as protein kinases which also attach phosphates to other amino acids such as serine and threonine. Phosphorylation of proteins by kinases is an important mechanism for communicating signals within a cell (signal transduction) and regulating cellular activity, such as cell division.

Protein kinases can become mutated, stuck in the "on" position, and cause unregulated growth of the cell, which is a necessary step for the development of cancer. Therefore, kinase inhibitors, such as imatinib and osimertinib, are often effective cancer treatments.

Most tyrosine kinases have an associated protein tyrosine phosphatase, which removes the phosphate group.

Tyrosine
L-Tyrosine or tyrosine (symbol Tyr or Y) or 4-hydroxyphenylalanine is one of the 20 standard amino acids that are used by cells to synthesize proteins. It is a conditionally essential amino acid with a polar side group. The word "tyrosine" is from the Greek tyrós, meaning cheese, as it was first discovered in 1846 by German chemist Justus von Liebig in the protein casein from cheese. It is called tyrosyl when referred to as a functional group or side chain. While tyrosine is generally classified as a hydrophobic amino acid, it is more hydrophilic than phenylalanine. It is encoded by the codons UAC and UAU in messenger RNA.

The one-letter symbol Y was assigned to tyrosine for being alphabetically nearest of those letters available. Note that T was assigned to the structurally simpler threonine, U was avoided for its similarity with V for valine, W was assigned to tryptophan, while X was reserved for undetermined or atypical amino acids. The mnemonic tYrosine was also proposed.
West Acton tube station
West Acton is a London Underground station in West Acton, London. It is on the Ealing Broadway branch of the Central line, between Ealing Broadway and North Acton stations. It is its only intermediate station in the branch. The station is a Grade II listed building. It is in London fare zone 3.

The station is close to North Ealing tube station on the Piccadilly line, 550 metres away at the western end of Queens Drive.

North Ealing tube station
North Ealing is a London Underground station in west London. It is on the Uxbridge branch of the Piccadilly line, between Park Royal and Ealing Common stations. The station is located on Station Road, a short distance from the junction of Queen's Drive and Hanger Lane (A406, North Circular Road). It is in London fare zone 3. West Acton tube station on the Central line is situated 550 metres to the east at the other end of Queen's Drive.

Despite its name, the station is geographically located to the east of Ealing Broadway; the areas of Gurnell, Pitshanger, Montpelier and Hanger Hill/Hanger Lane are more geographically suited to the term "North Ealing". There is even a primary school named North Ealing within Pitshanger.
Diocese of Guaranda
The Roman Catholic Diocese of Guaranda (Latin: Dioecesis Guarandensis) is a diocese located in the city of Guaranda in the ecclesiastical province of Quito. It was erected on 29 December 1957 from territory from the Diocese of Riobamba.

Archdiocese of Quito
The Roman Catholic Metropolitan Archdiocese of Quito is the Catholic archdiocese in the capital city of Ecuador, Quito. It was established as the Diocese of Quito on 8 January 1545, before being elevated to archdiocese level on January 13, 1848 by Pope Pius IX.
Fritz Mauthner
Fritz Mauthner (German: [ˈmaʊtnɐ]; 22 November 1849 – 29 June 1923) was an Austrian philosopher and author of novels, satires, reviews and journalistic works. He was an exponent of philosophical scepticism derived from a critique of human knowledge and of philosophy of language.

He became editor of the Berliner Tageblatt in 1895, but is remembered mainly for his Beiträge zu einer Kritik der Sprache (Contributions to a Critique of Language), published in three parts in 1901 and 1902. Ludwig Wittgenstein took several of his ideas from Mauthner, and acknowledges him in his Tractatus Logico-Philosophicus (1922).

Berliner Tageblatt
The Berliner Tageblatt or BT was a German language newspaper published in Berlin from 1872 to 1939. Along with the Frankfurter Zeitung, it became one of the most important liberal German newspapers of its time.
Piz Segnas
Piz Segnas is a mountain in the Glarus Alps, located on the border between the Swiss cantons of Glarus and Grisons (Graubünden).

The Piz Sardona is on the same ridge to the north, from where the Piz Dolf/Trinserhorn lies to the southeast. The Tschingelhörner with the famous Martinsloch (hole of St. Martin) lies to the west, with the Pass dil Segnas between the two mountains.

The mountain lies in the municipalities of Flims, in the canton of Grisons, and Glarus Süd, in the canton of Glarus. The nearest settlements are the villages of Flims, to the south, and Elm, to the west. A path crosses the Pass dil Segnas between the two villages. The easiest access to the area is an aerial cableway to Fil de Cassons (not active since 2015) from Flims or the hike to this ridge lying southeast of Piz Segnas.

Piz Dolf
Piz Dolf (Romansh) or Trinserhorn (German) is a mountain of the Glarus Alps, located on the border between the cantons of St. Gallen and Grisons (Graubünden).

Piz Sardona is to the north across a glacier, and to its west Piz Segnas. Both Piz Segnas and Piz Dolf show the line of the Glarus thrust in its upper part. The easiest access to the area is an aerial cableway to Fil de Cassons from Flims or any of various hikes to this ridge lying southeast of Piz Dolf. One route uses the ascent via Val Bargis.
Let Yourself Go: Celebrating Fred Astaire
Let Yourself Go: Celebrating Fred Astaire is a 2000 studio album by Stacey Kent.

This was Kent's third studio album, and was recorded in tribute to the dancer and singer Fred Astaire, who introduced many of the songs on this album.

Stacey Kent
Stacey Kent (born March 27, 1965) is an American jazz singer from South Orange, New Jersey.

Kent was nominated for a Grammy Award and was awarded the Chevalier de l'Ordre des Arts et des Lettres (Order of Arts and Letters) by the French Minister of Culture in 2009. She is married to saxophonist and composer Jim Tomlinson, who produces Kent's albums and writes songs for her with his lyricist partner, novelist Kazuo Ishiguro.
Prong (band)
Prong is an American heavy metal band formed in New York City in 1986. The band is fronted by guitarist/vocalist Tommy Victor, Prong's sole constant member. To date, they have released 13 studio albums (including a covers album), one live album, four EPs, one DVD and one remix album.

Prong had two independent releases, Primitive Origins (1987) and Force Fed (1988), which attracted the attention of Epic Records, who signed the band in 1989. Their first two albums on Epic, Beg to Differ (1990) and Prove You Wrong (1991), were released to critical acclaim and garnered attention on MTV's Headbangers Ball. The band's 1994 album Cleansing was also successful, and included their best-known song, "Snap Your Fingers, Snap Your Neck". After releasing one more album (Rude Awakening in 1996), Prong disbanded in 1997, but reformed in 2002 and has continued to tour and record since then.

Cleansing (album)
Cleansing is the fourth album by the American heavy metal band Prong, released on January 25, 1994, by Epic Records. It was produced by Terry Date, whereas Prong's previous two albums had been produced by Mark Dodson. The album features ex-Killing Joke members Paul Raven on bass guitar and John Bechdel on keyboards and programming. Featuring an industrial-influenced sound, the record received moderate commercial success.

The single "Snap Your Fingers, Snap Your Neck" received a commercial interest; its music video received heavy rotation on MTV and was featured on an episode of Beavis and Butt-Head. As a part of the album's promotion, the band toured with Sepultura and Pantera as an opener for their Chaos A.D. and Far Beyond Driven tours, respectively.

The record was reissued by SPV/Steamhammer in 2008.
Jarett Andretti
Jarett Andretti (born December 13, 1992) is an American racing driver from Charlotte, North Carolina. He is the son of IndyCar and NASCAR driver John Andretti, and the grandson of Aldo Andretti, the brother of Mario Andretti. He is also the second cousin of Marco Andretti.

John Andretti
John Andrew Andretti (March 12, 1963 – January 30, 2020) was an American professional race car driver. He won individual races in CART, IMSA GTP, Rolex Sports Car Series, and NASCAR during his career. A member of the Andretti racing family, he was the son of Aldo Andretti, older brother of racer Adam Andretti, nephew of Mario Andretti, and the cousin to CART drivers Michael and Jeff Andretti. He was also the first cousin once-removed of Marco Andretti.
Alin Bota
Alin Vasile Bota (born 29 May 1983) is a Romanian football goalkeeper who plays for Liga III side Minaur Baia Mare. In his career he also played for teams such as: CFR Cluj, CS Otopeni, FC Baia Mare or Gloria Bistrița and is well known for scoring from penalties.

CS Minaur Baia Mare (football)
Minaur Baia Mare, known also as Minerul Baia Mare, is a Romanian football club, based in Baia Mare, Maramureș County, northern Romania, founded in 1947. It currently plays in Romania's third division, Liga III. It played for seven seasons in Romania's first league, Liga I, last in 1995.
Kim Yo-han
Kim Yo-han (Korean: 김요한, born September 22, 1999), also known by the mononym Yohan (요한), is a South Korean singer and actor. He is a member of the boy group WEi and a former member of boy group X1, finishing first on Produce X 101. He made his solo debut with the digital single "No More" on August 25, 2020. He debuted in acting through A Love So Beautiful.

Produce X 101
Produce X 101 (Korean: 프로듀스 X 101) is a 2019 South Korean boy group survival reality show on Mnet and the fourth and final season of the Produce 101 franchise. The public, referred to as "national producers", "produces" a boy band by choosing 11 members among the 101 trainees from 47 different entertainment companies and independent trainees through online voting and live voting with multiple elimination rounds. The public will also choose the group's concept, debut song, and group name. The show aired from May 3 to July 19, 2019. Contestant Kim Yohan from Oui Entertainment obtained the most votes at the end, becoming the debut group center. The group from this show was named X1, but after extensive voting manipulation was proven, the group was disbanded on January 6, 2020.
Residual (entertainment industry)
Residuals are financial compensations that are paid to film or television actors, writers, directors, and others involved in making TV shows and movies in cases of the cable reruns, syndication, DVD release, or licensing to streaming media. Residuals are calculated by producers and studios, and administered by industry trade unions like SAG-AFTRA, the Directors Guild of America, and the Writers Guild of America. The word is typically used in the plural form.

SAG-AFTRA
The Screen Actors Guild–American Federation of Television and Radio Artists (SAG-AFTRA, /sæɡˈæftrə/) is an American labor union formed in 2012 by the merger of the Screen Actors Guild and the American Federation of Television and Radio Artists. It represents approximately 170,000 media professionals worldwide. SAG-AFTRA is a member of the AFL-CIO, the largest federation of unions in the United States. SAG-AFTRA is also a member of the International Federation of Actors.
Adib Khan
Adib Khan is an Australian novelist of Bangladeshi origin. He moved to Australia in 1973 and obtained an MA from Monash University in 1976. He taught creative writing at Ballarat University, and in 2007 returned to Monash to pursue a PhD.

Khan started writing in his 40s and has published five novels. His first novel, Seasonal Adjustments won the Christina Stead Prize for Fiction, the Book of the Year award in the 1994 NSW Premier′s Literary Awards, and the 1995 Commonwealth Writers' Prize for Best Book, and was also shortlisted for the 1994 Age Book of the Year award.
Solitude of Illusions was shortlisted for the Christina Stead Prize for Fiction, and the Ethnic Affairs Commission Award in the 1997 NSW Premier′s Literary Awards. It won the 1997 Tilly Aston Braille Book of the Year Award.

Seasonal Adjustments
Seasonal Adjustments is a 1994 novel by the Australian/Bangladeshi author Adib Khan, originally published by Allen & Unwin.

It was the winner of the 1994 New South Wales Premier's Literary Awards, Christina Stead Prize for Fiction, and won the Commonwealth Writers' Prize for Best First Book in the South East Asia and South Pacific Region in 1995.
Upwood
Upwood is a village and former civil parish, now in the parish of Upwood and the Raveleys, in the non-metropolitan district and historic county of Huntingdonshire, England, although in the administrative county of Cambridgeshire. Upwood lies approximately 7 miles (11 km) north of Huntingdon, near Bury. In 1931 the parish had a population of 322.

The village lies along the High Street which runs parallel to the main road from Great Raveley to Ramsey about 300 yards to the west. The church stands about the middle of the village and there are several 17th-century cottages to the north and south of it.

In September 1917, the Royal Air Force started work on RAF Upwood, a large airfield near the village used by both the RAF and latterly by the United States Air Force.

Three nature reserves, Lady's Wood, Ramsey Heights and Upwood Meadows, lie near to the village; the latter is a national nature reserve.

The village has a free Book Exchange housed in a red telephone box.

Bury, Cambridgeshire
Bury is a village and civil parish in Cambridgeshire, England. Bury lies approximately 7 miles (11 km) north/north east of Huntingdon and is near to Ramsey and St Ives. Bury is situated within Huntingdonshire which is a non-metropolitan district of Cambridgeshire as well as being a historic county of England.
Sydenham (New Zealand electorate)
Sydenham was a New Zealand parliamentary electorate, from 1881 to 1890 and again from 1946 to 1996. It had notable politicians representing it like Mabel Howard (the first female cabinet minister in New Zealand), Norman Kirk (who became Prime Minister while holding Sydenham) and Jim Anderton (a former  Father of the House, who started his parliamentary career in Sydenham).

Mabel Howard
Mabel Bowden Howard (18 April 1894 – 23 June 1972) was a well-known New Zealand trade unionist and politician. She was the first woman secretary of a predominantly male union (the Canterbury General Labourers' Union).

She was a Member of Parliament for the Labour Party from 1943 until 1969. In 1947 she became New Zealand's first woman cabinet minister when she was made Minister of Health and Minister in charge of Child Welfare. She is remembered for waving two large pairs of bloomers in Parliament in support of her successful campaign to have clothing sizes standardised.
College Football Hall of Fame
The College Football Hall of Fame is a hall of fame and interactive attraction devoted to American college football. The National Football Foundation (NFF) founded the Hall in 1951 to immortalize the players and coaches of college football that were voted first team All-American by the media.

In August 2014, the Chick-fil-A College Football Hall of Fame opened in downtown Atlanta. The facility is a 94,256 square feet (8,756.7 m2) attraction located in the heart of Atlanta's sports, entertainment and tourism district, and is adjacent to the Georgia World Congress Center and Centennial Olympic Park.

Centennial Olympic Park
Centennial Olympic Park is a 22-acre (89,000 m2) public park located in downtown Atlanta, Georgia, owned and operated by the Georgia World Congress Center Authority. It was built by the Atlanta Committee for the Olympic Games (ACOG) as part of the infrastructure improvements for the 1996 Summer Olympics. It plays host to millions of visitors a year and several events, including a summer popular music concert series (Wednesday WindDown), the annual SweetWater 420 Fest and an annual Independence Day concert and fireworks display.
Gusukube, Okinawa
Gusukube (城辺町, Gusukube-chō; Miyako: Gusїkubi) was a town located in Miyako District, Okinawa Prefecture, Japan.

As of 2003, the town had an estimated population of 7,042, a population density of 122.26 persons per km2, and a total area of 57.60 km2.

On October 1, 2005, Gusukube, along with the city of Hirara, and the towns of Irabu and Shimoji, and the village of Ueno (all from Miyako District), was merged to create the city of Miyakojima.

Hirara, Okinawa
Hirara (平良市, Hirara-shi), (Miyako: Pїsara) was a city located in Okinawa Prefecture, Japan on the island of Miyako. As of 2003, the city had an estimated population of 33,861 and a density of 521.58 persons per km2. The total area was 64.92 km2.
A Strange Mask of Identity
A Strange Mask of Identity (Hungarian: Különös ismertetőjel) is a 1955 Hungarian drama film directed by Zoltán Várkonyi and starring Ferenc Bessenyei, Erzsi Somogyi and Imre Sinkovits. The plot of the movie is set in the Hungarian communist resistance during Second World War. It was shot at the Hunnia Studios in Budapest. The film's sets were designed by the art director István Köpeczi-Boócz.

Erzsi Somogyi
Erzsi Somogyi (1906–1973) was a Hungarian stage and film actress. She was born in Transylvania in what subsequently became Romania after the First World War. She was active on the stage in Budapest for many decades, while also making film appearances. She was married to the actors János Pásztor and the writer Béla Gádor.
Brian Taylor (politician)
Brian Taylor is a medical cannabis activist and politician in British Columbia.  He and Marc Emery created the British Columbia Marijuana Party.  Brian was the first leader of the party during the 2001 provincial election.  He was a former mayor of Grand Forks in British Columbia, He was once nicknamed the "marijuana mayor".  Brian was featured on a CBC documentary called Cannabiz  about the medicinal marijuana industry.  "Cannabis Health" is a journal magazine that was created by Brian Taylor.   A company created by Brian Taylor is Grand Forks Cannabis Research Institute Inc.

Marc Emery
Marc Scott Emery (born February 13, 1958) is a Canadian cannabis rights activist, entrepreneur and politician. Often described as the "Prince of Pot", Emery has been a notable advocate of international cannabis policy reform, and has been active in multiple Canadian political parties at the provincial and federal levels. Emery has been jailed several times for his cannabis activism.

He is the estranged spouse of fellow activist Jodie Emery, with whom he operated Cannabis Culture magazine and Pot TV. Until the business was raided by police, the couple were co-owners of Cannabis Culture, a business that franchised pot dispensaries. Crown prosecutors later deemed the business to be illegal due to obtaining cannabis from illegal sources.
Padraig O'Malley
Padraig O'Malley (born 1942 in Dublin, Ireland) is an Irish international peacemaker, author, and professor. O'Malley specializes in the problems of divided societies, such as South Africa and Northern Ireland. He has written extensively on these subjects and has been actively involved in promoting dialogue among representatives of differing factions. He is currently the John Joseph Moakley Distinguished Professor of Peace and Reconciliation at the University of Massachusetts Boston.

University of Massachusetts Boston
The University of Massachusetts Boston (UMass Boston) is a public university in Boston, Massachusetts, United States.

The university is a member of the Coalition of Urban Serving Universities and the Coalition of Urban and Metropolitan Universities. It is classified among "R1: Doctoral Universities – Very high research spending and doctorate production". It is the only public research university in Boston and the third-largest campus in the five-campus University of Massachusetts system.
Coward, Fool, and Pro
Coward, Fool, and Pro (Russian: Трус, Балбес и Бывалый, Trus, Balbes, i Byvaly) are a trio of comical characters, petty criminals from Soviet cinema, first appeared in the films of Leonid Gaidai.  They were played accordingly, "Coward": Georgy Vitsin,  "Fool": Yuri Nikulin, "Pro": Yevgeny Morgunov. Initially appearing in Gaidai's satirical shorts, they gained all-Union popularity after the films 
Operation Y and Shurik's Other Adventures and Kidnapping, Caucasian Style, (further Shurik's New Adventures).

The exact moment of the creation of the trio is documented in the Mosfilm minutes: December 27, 1960, 17:30. At this moment the Mosfilm management approved the actors for their first common film, Dog Barbos and Unusual Cross.

In Moscow there is the Three Actors' Museum dedicated to them.

Kidnapping, Caucasian Style
Prisoner of the Caucasus or Shurik's New Adventures (Russian: Кавказская пленница, или Новые приключения Шурика) is a 1967 Soviet romantic musical comedy film dealing with a plot revolving around bride kidnapping, an old tradition that used to exist in certain regions of the Northern Caucasus.

The film was directed by Leonid Gaidai. It is the last film featuring the trio of the "Coward" (Georgy Vitsin), the "Fool" (Yuri Nikulin), and the "Pro" (Yevgeny Morgunov), a group of bumbling antiheroes similar in some ways to the American Three Stooges. The film premiered in Moscow on 1 April 1967.
Ivan Thys
Ivan Thys (29 April 1897 – 15 February 1982) was a Belgian footballer who played as a forward.

Ivan Thys played 203 games for Beerschot, scoring 132 goals and making him twice the Belgian First Division top scorer. He played in twenty matches for the Belgium national football team between 1921 and 1926.

Ivan Thys was the father of the future head coach of Belgium, Guy Thys.

Guy Thys
Guy Jean-Leonard Thys (6 December 1922 – 1 August 2003) was a Belgian football manager, mostly known for being the most successful manager in the history of the Belgium national football team as he managed to lead the national side to their only UEFA European Championship final in 1980 and a fourth–place finish at the 1986 FIFA World Cup. With 114 games between 1976 and 1991, he is the longest-serving national coach in the history of the Red Devils to date.
Maeda Toshimasa (1578)
Maeda Toshimasa (前田利政,  1578 – August 18, 1633) was a Japanese daimyō of the Sengoku period to the early Edo period, belonging to the Maeda clan. He was the second son of Maeda Toshiie and Maeda Matsu.

Maeda Toshiie
Maeda Toshiie (前田 利家; January 15, 1538 – April 27, 1599) was one of the leading generals of Oda Nobunaga following the Sengoku period of the 16th century extending to the Azuchi–Momoyama period. His preferred weapon was a yari, and Matazaemon (又左衛門) was his common name; he was therefore known as Yari no Mataza (槍の又左). He was a member of the so-called Echizen Sanninshu (Echizen Triumvir) along with Sassa Narimasa and Fuwa Mitsuharu. The highest rank from the court that he received is the Great Counselor Dainagon (大納言).