hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Phosphoinositide 3-kinase
Phosphoinositide 3-kinases (PI3Ks), also called phosphatidylinositol 3-kinases, are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in cancer.

PI3Ks are a family of related intracellular signal transducer enzymes capable of phosphorylating the 3 position hydroxyl group of the inositol ring of phosphatidylinositol (PtdIns). The pathway, with oncogene PIK3CA and tumor suppressor gene PTEN, is implicated in the sensitivity of cancer tumors to insulin and IGF1, and in calorie restriction.

Phosphatidylinositol 3-phosphate
Phosphatidylinositol 3-phosphate (PI3P) is a phospholipid found in cell membranes that helps to recruit a range of proteins, many of which are involved in protein trafficking, to the membranes. It is the product of both the class II and III phosphoinositide 3-kinases (PI 3-kinases) activity on phosphatidylinositol.

PtdIns3P is dephosphorylated by the myotubularin family of phosphatases, on the D3 position of the inositol ring, and can be converted to PtdIns(3,5)P2 by the lipid kinase PIKfyve.

Both FYVE domains and PX domains – found in proteins such as SNX1, HGS, and EEA1 – bind to PtdIns3P.

The majority of PtdIns3P appears to be constitutively synthesised by the class III PI 3-kinase, PIK3C3 (Vps34), at endocytic membranes. Class II PI 3-kinases also appear to synthesise PtdIns3P, their activity however appears to be regulated by a range of stimuli, including growth factors. This suggests that specific pools of PtdIns3P may be synthesised upon cell stimulation.
Ministry of Finance (Afghanistan)
The Ministry of Finance of Afghanistan (Dari: وزارت مالیه افغانستان, Pashto: د افغانستان د مالیې وزارت) is responsible for the implementation and execution of the budget, collection of taxes, organization, and control of public expenses in Afghanistan; it also controls the management of the Custom Affairs. The Ministry of Finance provides a quarterly report to inform the public and the executive cabinet of advancements in Afghanistan's financial sector. The current Finance Minister is Nasir Akhund.

Sayyid Abdulillah
Sayyid Abdulillah was an Afghan politician in Mohammad Daoud Khan administration as vice president, deputy prime minister and minister of finance.

He was born in 1945, educated in Afghanistan and obtained bachelor's degree in economics from Kabul University in 1970.

He served as Daoud's Vice President of Afghanistan (19 February 1978 - 29 April 1978) and Minister of Finance (March 1977 - April 1978). He was appointed to Vice President's office and Finance minister office by Mohammed Daoud Khan. He was Second Deputy Prime Minister from 1975 to 1978. He was also assassinated with Mohammed Daoud Khan on 29 April 1978.

Sayyid Abdulillah was a son of Sayyid Abdullah (He was born in 1923 in Farah, a former deputy of Wolesi Jirga from Shindand.).
Piozzano
Piozzano (Piacentino: Piusàn) is a comune (municipality) in the Province of Piacenza in the Italian region Emilia-Romagna, located about 150 kilometres (93 mi) northwest of Bologna and about 20 kilometres (12 mi) southwest of Piacenza.

Piozzano borders the following municipalities: Agazzano, ]Alta Val Tidone, Bobbio, Gazzola, Pianello Val Tidone, Travo.

Alta Val Tidone
Alta Val Tidone is a new comune (municipality) in the Province of Piacenza in the Italian region Emilia-Romagna, located about 180 kilometres (110 mi) northwest of Bologna and about 30 kilometres (19 mi) southwest of Piacenza.

Alta Val Tidone borders the following municipalities: Bobbio, Borgonovo Val Tidone, Canevino, Golferenzo, Pianello Val Tidone, Piozzano, Romagnese, Ruino, Santa Maria della Versa, Travo, Volpara, Zavattarello, Ziano Piacentino

It was formed on 1 January 2018 from the union of Caminata, Nibbiano and Pecorara.
Kinnelon High School
Kinnelon High School is a four-year comprehensive community public high school that serves students in ninth through twelfth grades from Kinnelon in Morris County, in the U.S. state of New Jersey, operating as the lone secondary school of the Kinnelon Public Schools.

As of the 2023–24 school year, the school had an enrollment of 528 students and 57.0 classroom teachers (on an FTE basis), for a student–teacher ratio of 9.3:1. There were 22 students (4.2% of enrollment) eligible for free lunch and 3 (0.6% of students) eligible for reduced-cost lunch.

Butler High School (New Jersey)
Butler High School is a four-year public high school that serves students in ninth through twelfth grades from Butler, in Morris County, in the U.S. state of New Jersey, operating as the lone secondary school of the Butler Public Schools.

Students from Bloomingdale attend Butler High School as part of a sending/receiving relationship with the Bloomingdale School District. In 2020–21, more than 40% of the students in the high school came from Bloomingdale.

As of the 2024–25 school year, the school had an enrollment of 482 students and 38.0 classroom teachers (on an FTE basis), for a student–teacher ratio of 12.7:1. There were 116 students (24.1% of enrollment) eligible for free lunch and 18 (3.7% of students) eligible for reduced-cost lunch.
Abba bar Kahana
Rabbi Abba bar Kahana (Hebrew: רבי אבא בר כהנא) was an amora of the 3rd generation.

His father was Rav Kahana II. He was born in Babylonia, and learned in the beit midrash of Rabbi Hiyya bar Ashi. He moved to the Land of Israel while Rabbi Hanina bar Hama was still alive.

His teachers include Rabbi Helbo and Rabbi Yehoshua ben Levi. His colleagues include Levi II and Rabbi Zeira. Rabbi Berekiah cited many teaching in his name, and apparently was his student.

He is principally known for his many aggadic teachings.

Rav Kahana II
For other Amoraic sages of Babylonia with the name "Rav Kahana", see Rav Kahana.

Rav Kahana (II) (Hebrew: רב כהנא (השני), read as Rav Kahana (Ha-sheni), lit. "Rabbi Kahana (II)"; recorded in the Talmud merely as Rav Kahana) was an Amora of the second generation, active in Babylon and in the Land of Israel.
Armina californica
Armina californica is a species of sea slug, a nudibranch, a marine gastropod mollusk in the family Arminidae.

This species occurs in the Eastern Pacific Ocean from Vancouver Island to Panama. It can commonly be found in a soft-bottom habitat from 1-230 meters in depth. Armina californica is characterized by longitudinal ridges of varying colors including light pink, cream, and brown. Features that differentiate Armina californica from the larger Armina species are separated rhinophores, rachidian teeth with 8-13 elongated denticles, and lateral teeth with 7-9 triangular denticles.

Armina
Armina is a genus of sea slugs, specifically nudibranchs, marine gastropod mollusks in the family Arminidae.

Armina loveni is known to prey on pennatulacean octocorals, consuming the polyps of these colonial animals.
NSB Class 71
NSB Class 71 (Norwegian: type 71) is an electric multiple unit used by Flytoget for the Airport Express Trains on the Gardermoen Line of Norway. Sixteen three-car train sets were built by Adtranz Strømmen between 1997 and 1998. The units are capable of 210 km/h (130 mph), connecting Oslo Central Station and other stations in Metropolitan Oslo to the Oslo Airport, Gardermoen, along Norway's only high-speed railway.

In a three-car configuration, the units weigh 158 tonnes (156 long tons; 174 short tons) and are 82.3 metres (270 ft 0 in) long, with a power output of 2,645 kW (3,547 hp). The units are similar to the NSB Class 73, and are related to the Swedish X2 units. By 2009, all units were expanded with a fourth car.

Vy
Vygruppen, branded as Vy, formerly the Norwegian State Railways (Norwegian: Norges Statsbaner, NSB), is a government-owned railway company which operates most passenger train services and many bus services in Norway. The company is owned by the Norwegian Ministry of Transport. Its sub-brands include Vy Buss coach services, CargoNet freight trains and the Swedish train transport company Tågkompaniet.  In 2009, NSB carried 52 million train passengers and 104 million bus passengers.  On 24 April 2019, passenger train and bus services were rebranded as Vy.

The company was established as the Norwegian State Railways (1883–1996). In 1996 the company was split into the new NSB, the infrastructure company, Jernbaneverket and the Norwegian Railway Inspectorate. In 2002, the freight operations were split to the subsidiary CargoNet, and the maintenance department became Mantena. It was controversially renamed Vygruppen in 2019; the then-opposition parties vowed to reverse the name change.
Second Cooper ministry
The Cooper Ministry[1] was a ministry of the Government of Queensland and was led by National Party Premier Russell Cooper and Deputy Premier Bill Gunn. It succeeded the Ahern Ministry on 25 September 1989 following a party-room ballot, and was in turn succeeded by the Goss Ministry on 7 December 1989 following the National government's defeat at the 1989 state election by the Labor Party, led by Wayne Goss. Seven of the outgoing ministry lost their seats at the election.

On 25 September 1989, the Governor designated 18 principal executive offices of the Government and appointed the following Members of the Legislative Assembly of Queensland to the Ministry as follows. As the National Party was not in coalition at the time, all listed members are from that party.

1  An earlier Cooper Ministry was headed by Labor Premier Frank Cooper from 1942 until 1946. Both ministries were officially styled "The Cooper Ministry".

Ahern ministry
The Ahern Ministry was a ministry of the Australian Government of Queensland and was led by National Party Premier Mike Ahern and Deputy Premier Bill Gunn. It succeeded the Bjelke-Petersen Ministry on 1 December 1987 following Joh Bjelke-Petersen's resignation as Premier and from Parliament, and was in turn succeeded by the Cooper Ministry on 25 September 1989, led by Russell Cooper.

As the National Party was not in coalition at the time, all listed members are from that party.
Hieratic
Hieratic (/haɪəˈrætɪk/; Ancient Greek: ἱερατικά, romanized: hieratiká, lit. 'priestly') is the name given to a cursive writing system used for Ancient Egyptian and the principal script used to write that language from its development in the third millennium BCE until the rise of Demotic in the mid-first millennium BCE. It was primarily written in ink with a reed brush on papyrus.

Hieratic should not be confused with cursive hieroglyphs. The two were indistinct during the Old Kingdom but separated into different writing systems during the First Intermediate Period.

Ligature (writing)
In writing and typography, a ligature occurs where two or more graphemes or letters are joined to form a single glyph. Examples are the characters ⟨æ⟩ and ⟨œ⟩ used in English and French, in which the letters ⟨a⟩ and ⟨e⟩ are joined for the first ligature and the letters ⟨o⟩ and ⟨e⟩ are joined for the second ligature. For stylistic and legibility reasons, ⟨f⟩ and ⟨i⟩ are often merged to create ⟨ﬁ⟩ (where the tittle on the ⟨i⟩ merges with the hood of the ⟨f⟩); the same is true of ⟨s⟩ and ⟨t⟩ to create ⟨ﬆ⟩. The common ampersand, ⟨&⟩, developed from a ligature in which the handwritten Latin letters ⟨e⟩ and ⟨t⟩ (spelling et, Latin for 'and') were combined.
Oxidopamine
Oxidopamine, also known as 6-hydroxydopamine (6-OHDA) or 2,4,5-trihydroxyphenethylamine, is a synthetic monoaminergic neurotoxin used by researchers to selectively destroy dopaminergic and noradrenergic neurons in the brain.

The main use for oxidopamine in scientific research is to induce Parkinsonism in laboratory animals by lesioning the dopaminergic neurons of the substantia nigra pars compacta, in order to develop and test new medicines and treatments for Parkinson's disease.

MPTP
MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is an organic compound. It is classified as a tetrahydropyridine. It is of interest as a precursor to the monoaminergic neurotoxin MPP+, which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain. It has been used to study disease models in various animals.

While MPTP itself has no psychoactive effects, the compound may be accidentally produced during the manufacture of MPPP, a synthetic opioid drug with effects similar to those of morphine and pethidine (meperidine). The harmful effects of MPTP were first discovered when a group of people fell ill after injecting illegally obtained MPPP.
Say Lou Lou
Say Lou Lou (formerly Saint Lou Lou) are a twin sister musical duo hailing from Australia and Sweden. Anna Miranda and Elektra June Kilbey-Jansson (born 7 June 1991) are the daughters of Steve Kilbey, the lead singer of Australian alternative band The Church, and Karin Jansson, ex-girlfriend and recording partner of Kilbey (and before then a member of Swedish new wave band Pink Champagne). They grew up in both Australia and Sweden.

The duo released their first single in 2012 before forming their own record label, à Deux, in 2013. In December 2013, it was announced that Say Lou Lou had made the BBC Sound of 2014 longlist.

Over the course of 2012 to 2014, Say Lou Lou released five singles, and their debut studio album, Lucid Dreaming, was released on 23 February 2015 in Scandinavia and 6 April 2015 elsewhere. On 26 October 2018, the duo released their second studio album, Immortelle.

Steve Kilbey
Steven John Kilbey (born 13 September 1954) is an English-born Australian singer-songwriter best known as the lead singer and bass guitarist for the rock band The Church. He is also a music producer, poet, and painter. As of 2020, Kilbey has released 14 solo albums and has collaborated on recordings with musical artists such as Martin Kennedy, Stephen Cummings and Ricky Maymi as a vocalist, musician, writer and/or producer. Ian McFarlane writes that "Kilbey's solo recordings [are] challenging and evocative. They ran the gamut of sounds and emotions from electronic and avant-garde to acoustic and symphonic, joyous and dreamy to saturnine and sardonic".

As of 2020, Kilbey has over 1,000 original songs registered with Australian copyright agency Australasian Performing Right Association.
1990–91 Pepperdine Waves men's basketball team
The 1990–91 Pepperdine Waves men's basketball team represented Pepperdine University in the 1990–91 NCAA Division I men's basketball season. The team was led by head coach Tom Asbury. The Waves played their home games at the Firestone Fieldhouse and were members of the West Coast Conference. They finished the season 22–9, 13–1 in WCC play to win the regular season conference title by a 4-game margin. After a January 11 home loss to San Diego in the conference opener, Pepperdine was just 6–8 overall. The Waves then went on a 16-game winning streak and won the West Coast Conference tournament to receive the conference's automatic bid to the NCAA tournament. In the opening round, the Waves fell to Seton Hall, 71–51.

1991 West Coast Conference men's basketball tournament
The 1991 West Coast Conference men's basketball tournament was the fifth edition of the tournament, held March 2–4 at the Toso Pavilion at Santa Clara University in Santa Clara, California.

Top seed Pepperdine entered the tournament on a thirteen-game winning streak and defeated #4 seed Saint Mary's in the championship game, 71–68 in overtime, to win the Waves' first WCC tournament title.

Pepperdine's Doug Christie, the WCC player of the year, sprained his right knee in the quarterfinal opener against Portland, which ended his season.

The Waves received the conference's automatic bid to the 64-team NCAA tournament as the fourteenth seed in the West regional.
Heymans (crater)
Heymans is a lunar impact crater that is located in the northern part of the Moon on the far side from the Earth. It lies between the craters Poinsot to the north and Hippocrates slightly farther to the south. To the southeast of Heymans is the larger Mezentsev.

This crater has been worn by subsequent impacts, but retains the general appearance of its original form. At the north end a small crater overlies the rim, and there are smaller impacts across the rim to the east and south. But the rim is generally round and symmetrical, with a slightly narrower inner wall to the northeast. Within the rim, the interior floor is level and nearly featureless.

Mezentsev (crater)
Mezentsev is a lunar impact crater that is located in the high northern latitudes on the Moon's far side. It lies just to the west of the smaller Niepce. To the southwest is the larger Stebbins, to the west-southwest is Hippocrates and to the northwest is Heymans.

This is a worn and eroded crater with a low outer rim and a relatively level interior. The circular nature of the rim can still be seen, but a number of impacts lie across the rim and the edge is generally softened and rounded. A smaller, unnamed crater is attached to the southwestern rim, with the satellite crater Mezentsev S laid across the western rim of this feature. The interior floor is roughly level but with some small craterlets marking the surface. The most prominent of these is a fresh, cup-shaped crater in the western half of the interior.

On some maps this crater has been labelled 'Mesentsev'.
Alizapride
Alizapride (Litican, Plitican, Superan, Vergentan) is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. It is  structurally related to metoclopramide and other benzamides.

Antiemetic
An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anaesthetics, and chemotherapy directed against cancer. They may be used for severe cases of gastroenteritis, especially if the patient is dehydrated.

Some antiemetics previously thought to cause birth defects appear safe for use by pregnant women in the treatment of morning sickness and the more serious hyperemesis gravidarum.
Ionian Islands
The Ionian Islands (Modern Greek: Ιόνια νησιά, Ionia nisia; Ancient Greek, Katharevousa: Ἰόνιαι Νῆσοι, Ioniai Nēsoi) are a group of islands in the Ionian Sea, west of mainland Greece. They are traditionally called the Heptanese ("Seven Islands"; Ἑπτάνησα, Heptanēsa or Ἑπτάνησος, Heptanēsos; Italian: Eptaneso), but the group includes many smaller islands in addition to the seven principal ones.

As a distinct historic region, the collective of islands date to the centuries-long Venetian rule, which kept them outside Ottoman control, and created a distinct cultural identity with many Italian influences. The Ionian Islands became part of the modern Greek state in 1864. Administratively today, they belong to the Ionian Islands Region except for Kythera, which belongs to the Attica Region.

Paxos
Paxos (Greek: Παξός) is a Greek island in the Ionian Sea, lying just south of Corfu. As a group with the nearby island of Antipaxos and adjoining islets, it is also called by the plural form  Paxi or Paxoi (Greek: Παξοί, pronounced /pækˈsiː/ in English and [paˈksi] in Greek). The main town and the seat of the municipality is Gaios. The smallest of the seven main Ionian Islands (the Heptanese), Paxos has an area of 25.3 square kilometres (9.8 sq mi), while the municipality has an area of 30.121 km2 (11.630 sq mi) and a population of about 2,500.

Paxos lies some 15 km from the southern tip of Corfu and at about the same distance from the town of Parga on the mainland. It is connected by ferry lines from Igoumenitsa and Corfu with Gaios. The island is hilly, the highest point having an elevation of 230 m.

In Greek mythology, Poseidon created the island by striking Corfu with his trident, so that he and his wife Amphitrite could have some peace and quiet.
Plumpton, New South Wales
Plumpton is a western suburb of Sydney. It is located 45 km (28 mi) west of the Sydney central business district, in the local government area of the City of Blacktown. In 2021, the population was 10,070. As shown in the 2021 Australian census, Plumpton is a very multicultural area, with 55.3% of residents born overseas, including a high population of Filipinos.

Blacktown railway station
Blacktown railway station is a suburban railway station located on the Main Western line, serving the Sydney suburb of Blacktown. It is served by Sydney Trains T1 Western Line and T5 Cumberland Line services as well as intercity Blue Mountains Line and NSW TrainLink Central West XPT services.
Stanisław Radziejowski
Stanisław Radziejowski (1575–1637) was a Polish nobleman, Voivode of Rawa, Voivode of Łęczyca, starost of Sochaczew, castellan of Rawa Mazowiecka.

Married firstly Katarzyna Sobieska, father of Hieronim Radziejowski, later married to Krystyna Sapieha, the daughter of Jan Piotr Sapieha.

Jan Piotr Sapieha
Jan Piotr Sapieha (English: John Peter Sapieha; 1569–1611) was a Polish–Lithuanian nobleman, general, politician, diplomat, governor of Uświat county, member of the Parliament and a skilled commander of the Polish troops stationing in the Moscow Kremlin.

Sapieha was a participant in the Polish–Swedish War of 1600–1611; he brought a private regiment of 100 Cossacks and commanded the right wing of the Polish–Lithuanian army during the famous Battle of Kircholm in 1605, consisting of 400 winged hussars and 700 mounted Cossacks. He also participated in the Polish–Russian War of 1609–1618, where he commanded the failed siege of Troitse-Sergiyeva Lavra in 1608 and later fought anti-Polish Muscovite forces near Moscow, led by Prokopy Lyapunov. He died suddenly on 15 October, during the siege of the Moscow Kremlin.

Known for his ruthlessness towards the Russian peoples, he was nicknamed Pan Hetman, literally meaning Mr General.
Apostle Islands National Lakeshore
The Apostle Islands National Lakeshore is a U.S. national lakeshore consisting of 21 islands (Apostle Islands) and shoreline encompassing 69,540 acres (28,140 ha) on the northern tip of Wisconsin on the shore of Lake Superior.
It is known for its collection of historic lighthouses, sandstone sea caves, a few old-growth remnant forests, and natural animal habitats. It is featured on the America the Beautiful Quarters series.

The Apostle Islands National Lakeshore is located in Bayfield, Wisconsin, on Lake Superior, the "largest, cleanest, and coldest of the Great Lakes". The lakeshore comprises beaches, cliffs, water, and 21 islands. Of its area, 42,308 acres is land and 27,232 acres is water, extending 1/4 mile from the 155 miles of shoreline. Madeline Island, with commercial establishments of the town of La Pointe, is the only one of the Apostle Islands not included in the national lakeshore, although a portion of the island is protected as Big Bay State Park.

Devils Island Light
The Devils Island Lighthouse is a lighthouse located on Devils Island, one of the Apostle Islands, in Lake Superior in Ashland County, Wisconsin, near the city of Bayfield. Among the Apostle Islands lighthouses—a testament to its remoteness—it was the last built, and the last automated and unmanned.
Sviatopolk II of Kiev
Sviatopolk II Iziaslavich (Old East Slavic: Свѧтополкъ Изѧславичь, romanized: Svętopolkǐ Izęslavičǐ; 8 November 1050 – 16 April 1113) was Grand Prince of Kiev from 1093 to 1113. He was not a popular prince, and his reign was marked by incessant rivalry with his cousin Vladimir Monomakh.

Prince of Turov
The Prince of Turov was the kniaz, the ruler or sub-ruler, of the Rus' Principality of Turov, a lordship based on the city of Turov, now Turaŭ in Homiel Voblast, Belarus.

Although not mentioned in his Testament of 1054, the city of Turov was ruled by the descendants of Iziaslav Iaroslavich, Grand Prince of Kiev. It fell into the control of  Vladimir Monomakh and the latter's son Mstislav Vladimirovich, who delegated control,  until the Iaroslavichi regained control in 1157 in the person of Iurii Iaroslavich in 1157.