hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Rare variant (genetics)
A rare variant is a genetic variant which occurs at low frequency in a population.  Rare variants play a significant role in both complex and Mendelian disease and are responsible for a portion of the missing heritability of complex diseases. The theoretical case for a significant role of rare variants is that alleles that strongly predispose an individual to disease will be kept at low frequencies in populations by purifying selection. Rare variants are increasingly being studied, as a consequence of whole exome and whole genome sequencing efforts. While these variants are individually infrequent in populations, there are many in human populations, and they can be unique to specific populations.  They are more likely to be deleterious than common variants, as a result of rapid population growth and weak purifying selection.  They have been suspected of acting independently or along with common variants to cause disease states.

Exome sequencing
Exome sequencing, also known as whole exome sequencing (WES), is a genomic technique for sequencing all of the protein-coding regions of genes in a genome (known as the exome). It consists of two steps: the first step is to select only the subset of DNA that encodes proteins. These regions are known as exons—humans have about 180,000 exons, constituting about 1% of the human genome, or approximately 30 million base pairs. The second step is to sequence the exonic DNA using any high-throughput DNA sequencing technology.

The goal of this approach is to identify genetic variants that alter protein sequences, and to do this at a much lower cost than whole-genome sequencing. Since these variants can be responsible for both Mendelian and common polygenic diseases, such as Alzheimer's disease, whole exome sequencing has been applied both in academic research and as a clinical diagnostic.
Manor house
A manor house was historically the main residence of the lord of the manor. The house formed the administrative centre of a manor in the European feudal system; within its great hall were usually held the lord's manorial courts, communal meals with manorial tenants and great banquets. The term is today loosely (though erroneously) applied to various English country houses, mostly at the smaller end of the spectrum, sometimes dating from the Late Middle Ages, which currently or formerly house the landed gentry.

Manor houses were sometimes fortified, albeit not as fortified as castles, but this was often more for show than for defence. They existed in most European countries where feudalism was present.

Fortified house
A fortified house or fortified mansion, from French maison forte, is a type of building which developed in Europe during the Middle Ages, generally with significant fortifications added. During the earlier Roman period it was common for wealthy landowners to construct unfortified villas on their lands. After the fall of Rome, increased social instability and military conflict necessitated more austere, defensible types of structures. A castle is a type of particularly well-fortified residence. In English-language academic works of castellology, the French term maison-forte is also used, more seldom unhyphenated (maison forte).
Shrikhandi Bhittha
Bhitthamore or Shrikhandi Bhittha is a significant human settlement in the Sitamarhi district of the Indian state of Bihar. It is located near the India–Nepal border, along the Ratnawati (Raato) River, serving as a major transit and trade hub. The settlement is a key junction on National Highway 227 connecting it to its district headquarters Sitamarhi (30 km), as well as Janakpur (23 km) and Jaynagar (55 km). The area hosts the Integrated Check Post (ICP) Bhitthamore and is monitored by the Sashastra Seema Bal (SSB).

Sitamarhi district
Sitamarhi district is one of the districts in the Indian state of Bihar. Dumra is the administrative headquarters of this district. The district is a part of the Tirhut division It is believed to be the place of manifestation of Goddess Sita in the ancient Mithila Kingdom while the legendary King Janaka in the epic Ramayana was ploughing a farm field in the present city of Sitamarhi. Presently in the city of Sitamarhi, there are two locations claimed to be the birthplace of the Goddess Sita. The two locations are Urvija Kund at Janaki Sthan and Janaki Kund at Punauradham.
Marge Piercy
Marge Piercy (born March 31, 1936) is an American progressive activist, feminist, and writer. Her work includes Woman on the Edge of Time; He, She and It, which won the 1993 Arthur C. Clarke Award; and Gone to Soldiers, a New York Times Best Seller and a sweeping historical novel set during World War II. Piercy's work is rooted in her Jewish heritage, Marxist social and political activism, and feminist ideals.

He, She and It
He, She, and It (retitled Body of Glass in the United Kingdom) is a 1991 cyberpunk novel by American writer Marge Piercy. It won the Arthur C. Clarke Award for Best Science Fiction Novel in 1993. The novel, set in an post-apocalyptic America, follows a romance between a human woman and a cyborg created to protect her community from corporate raiders. The novel also interweaves a secondary narrative of the creation of a golem in 17th century Prague. Like Piercy's earlier novel Woman on the Edge of Time (1976), He, She, and It also examines themes such as gender roles, political economy, and environmentalism. In the mid-twenty-first century, Norika (formerly North America) is a toxic wasteland. Dominated by powerful corporations known as "multis", the region includes environmental domes, independent "free towns", and the chaotic "Glop", where most Norikans live in violent, polluted conditions ruled by gangs and warlords.
Britt Allcroft
Britt Allcroft (born Hilary Mary Allcroft; 14 December 1943 – 25 December 2024) was an English screenwriter, producer, director, and voice actress. She adapted Wilbert Awdry's The Railway Series in the form of the children's television series Thomas the Tank Engine & Friends (later retitled Thomas & Friends). She created Shining Time Station (with Rick Siggelkow), Mr. Conductor's Thomas Tales, and Magic Adventures of Mumfie. She also wrote, co-produced, and directed the film Thomas and the Magic Railroad (2000).

Magic Adventures of Mumfie
Magic Adventures of Mumfie (full on-screen title: Britt Allcroft's Magic Adventures of Mumfie) is an animated children's television series and movie, inspired by the Mumfie books written and illustrated by British author Katharine Tozer (1907–1943). The first series in 1994, spanning one continuous storyline, has a music score containing more than 20 songs. The series was created by Britt Allcroft (the creator of Thomas & Friends and its US debut, Shining Time Station), produced by The Britt Allcroft Company, narrated by American actor Patrick Breen and directed by John Laurence Collins, with animation produced in Toronto at Phoenix Animation Studios. Mumfie was first seen in the United States on the Fox Kids Network from 1995 to 1996, as part of The Fox Cubhouse. The second and third series debuted on the Fox Family Channel. 79 episodes were produced. The worldwide rights have reverted to Britt Allcroft.
Shallum of Israel
Shallum of Israel (Hebrew: שַׁלּוּם Šallūm, "retribution", fl. mid-8th century BC), was the fifteenth king of the ancient Kingdom of Israel, and the son of Jabesh, who reigned for only one month in 752 BCE.

Jabesh
Jabesh (Hebrew: יָבֵשׁ, romanized: ja'-besh) was the father of Shallum of the Kingdom of Israel according to the Hebrew Bible.

Jabesh is mentioned In the Books of Kings (2 Kings 15:10, 2 Kings 15:13–14). However, the passage may instead mention a toponym, identifying that Shallum was "the son" of a city called Jabesh. In this view, Shallum may have originated from the Israelite town of Jabesh-Gilead.

The name means "dry" in Hebrew.
Diamond White
Diamond White (born January 1, 1999) is an American singer and actress. In 2012, she was a contestant on the second season of the U.S. version of The X Factor, where she finished in fifth place. She voices Frankie Greene on the Discovery Family series Transformers: Rescue Bots, Fuli on the Disney Junior series The Lion Guard and had a cameo appearance on The Haunted Hathaways and has recurring roles on Sofia the First and Phineas and Ferb. She also provided the voice of Babs Byuteman on the 2019 Netflix series, Pinky Malinky. From November 2020 to July 2024, she played the contract role of Paris Buckingham on the CBS soap opera The Bold and the Beautiful. In 2021, she began voicing Lunella Lafayette/Moon Girl in the Disney Channel animated series Moon Girl and Devil Dinosaur, which premiered in early 2023.

Moon Girl And Devil Dinosaur
Moon Girl and Devil Dinosaur is a superhero comic book series published by Marvel Comics, featuring Lunella Lafayette / Moon Girl and Devil Dinosaur as its main protagonists, respectively a 9-year-old Inhuman girl who is described as the smartest character in the Marvel Universe, and a dinosaur with whom she shares a mental link. Written by Brandon Montclare and Amy Reeder and primarily drawn by Natacha Bustos, the series is a direct (yet stand-alone) sequel to Moon-Boy and Devil Dinosaur by Jack Kirby. The series lasted 47 issues, from November 2015 to September 2019.

An animated television series adaptation, starring Diamond White and Fred Tatasciore as the titular characters, aired for two seasons from February 2023 to March 2025. A brief relaunch of the comic book, subtitled Menace on Wheels, was published in 2023 as a tie-in with the series.
Gorkha regiments (India)
At the time of Indian Independence in 1947, as per the terms of the Britain–India–Nepal Tripartite Agreement, six Gorkha regiments, formerly part of the British Indian Army, became part of the Indian Army and have served ever since. The troops are mainly from ethnic Gurkha communities of Nepal. A seventh Gorkha Rifles regiment was formally re-raised in the Indian Army after Independence to accommodate the dedicated Gorkha soldiers of the 7th Gurkha Rifles and the 10th Gurkha Rifles who chose not to transfer to the British Army.

11th Gorkha Rifles
The 11th Gorkha Rifles  is a Gorkha regiment of the Indian Army that was re-raised after independence. The regiment consists of primarily the Kirant Tribes Rai and Limbu and small numbers of Sunuwars, Tamangs and Yakkhas of Eastern Nepal,  Darjeeling, Kalimpong, Dooars of West Bengal, Sikkim and other parts of  Northeast India. Though it is considered to be the youngest of the Gorkha regiments its lineage is as long as those of the 7th Gurkha Rifles and 10th Gurkha Rifles.

The regiment has participated in all major military operations India has undertaken since independence including in the Indo-Pakistani War of 1947, Operation Polo in 1948, the Indo-Pakistani War of 1965, the Indo-Pakistani War of 1971, and the Kargil War in 1999. Units of the regiment have also deployed abroad on UN missions.
Rural Municipality of North Cypress
The Rural Municipality of North Cypress is a former rural municipality (RM) in the  Canadian province of Manitoba. It was originally incorporated as a rural municipality on January 1, 1883. It ceased on January 1, 2015 as a result of its provincially mandated amalgamation with the RM of Langford to form the Municipality of North Cypress – Langford.

As of 2011, the population of the former RM of North Cypress is 1,860.

Municipality of North Cypress-Langford
The Municipality of North Cypress – Langford is a rural municipality (RM) in the Canadian province of Manitoba.
It is located northeast and east of the City of Brandon.  The town of Neepawa borders the RM to the north. Canadian Forces Base Shilo is also adjacent to the RM.
Pottery of Metepec
The pottery of Metepec is that of a municipality in central Mexico, located near Mexico City. It is noted for durable utilitarian items but more noted for its decorative and ritual items, especially sculptures called “trees of life,” decorative plaques in sun and moon shapes and mermaid like figures called Tlanchanas.  Metepec potters such as the Soteno family have won national and international recognition for their work and the town hosts the annual Concurso Nacional de Alfarería y Cerámica.

Metepec
Metepec  (Spanish: [meteˈpek] ⓘ) is a municipality in the State of Mexico in Mexico and is located directly to the east of the state capital, Toluca, at an altitude of 2,635 metres (8,645 ft) above sea level. The center of  Mexico City lies some 50 km further to the east. The city of Metepec also form part of the Greater Toluca. The name Metepec comes from Náhuatl meaning hill of the agave plants. However, it is also known in the Matlatzinca language as "Nepinta-Tuhi" meaning 'people of corn land' and in the Otomi language as "Ntaguada".
Bedessa, Wolaita
Bedessa (Geʽez: በዴሳ, Wolayttattuwa: Baddeessa) is a town and separate district in Wolayita Zone of the South Ethiopia Regional State, Ethiopia.  The town is administrative capital of Damot Weyde district of Wolayita Zone, Ethiopia. Bedessa is located about 373 KM away from Addis Ababa to the south on Sodo-Dimtu-Hawassa road, and 21 KM away from Sodo, the capital of Wolaita Zone. The amenities in the town are, 24 hours electricity, pure public water, banks, schools, postal service, telecommunications services and others. The town has a wire bridge which connects the town with other surrounding communities. Bedessa lies between 6°52'58.9"N 37°55'58.5"E.

Wolayita Zone
Wolayita or Wolaita is an administrative zone in Ethiopia.  Wolayita is bordered on the south by Gamo Zone, on the west by the Omo River which separates it from Dawro, on the northwest by Kembata Zone and Tembaro Special Woreda, on the north by Hadiya, on the northeast by the Oromia Region, on the east by the Bilate River which separates it from Sidama Region, and on the south east by the Lake Abaya which separates it from Oromia Region. The administrative centre of Wolayita is Wolaita Sodo. Other major towns are Areka, Boditi, Tebela, Bale Hawassa, Gesuba, Gununo, Bedessa and Dimtu.

Wolayita has 358 kilometres (222 mi) of all-weather roads and 425 kilometres (264 mi) of dry-weather roads, for an average road density of 187 kilometres per 1000 square kilometres. Its highest point is Mount Damota (2738 meters).
Jennifer Wexton
Jennifer Lynn Wexton (née Tosini, May 27, 1968) is an American politician and lawyer who  served as the U.S. representative for Virginia's 10th congressional district from 2019 to 2025. A member of the Democratic Party, she previously served in the Virginia Senate from 2014 to 2019.

Prior to her election to Congress, she represented the 33rd district, which includes parts of Fairfax and Loudoun Counties from 2014 to 2019.

In 2018, Wexton defeated Republican incumbent Barbara Comstock with 56% of the vote. She was re-elected in 2020 and 2022. Some commentators have described Wexton as a moderate Democrat. In September 2023, after being diagnosed with progressive supranuclear palsy, Wexton announced that she would not seek re-election in 2024. She was succeeded by Democratic state senator Suhas Subramanyam.

Virginia's 33rd Senate district
Virginia's 33rd Senate district is one of 40 districts in the Senate of Virginia. It has been represented by Democrat Jennifer Boysko since a 2019 special election to replace fellow Democrat Jennifer Wexton, who had been elected to Congress.
Karlsøy Municipality
Karlsøy (Northern Sami: Gálssa suohkan) is an island municipality in Troms county, Norway. The administrative centre of the municipality is the village of Hansnes. Other villages include Dåfjord, Hessfjord, Karlsøya, Torsvåg, Vannvåg, and Vannareid. The municipality is made up of many islands including Ringvassøya, Reinøya, Vannøya, Karlsøya, and Rebbenesøya plus several uninhabited islands (many of which were formerly inhabited). Some of the currently uninhabited islands include Helgøya, Nordkvaløya, Grøtøya, and Nordfugløya.

The 1,092-square-kilometre (422 sq mi) municipality is the 103rd largest by area out of the 357 municipalities in Norway. Karlsøy is the 268th most populous municipality in Norway with a population of 2,237. The municipality's population density is 2 inhabitants per square kilometre (5.2/sq mi) and its population has decreased by 4.2% over the previous 10-year period.

Karlsøya, Troms
Karlsøya (Norwegian) or Gálsá (Northern Sami) is an island in Karlsøy Municipality in Troms county, Norway.  The 7.91-square-kilometre (3.05 sq mi) island of Karlsøya lies directly south of the island of Vannøya and northeast of the island of Reinøya, along the western side of the Ullsfjorden.  The one village area on the island is known as Karlsøy and in 2001, it had a population of 70.

The island was the centre of the prestegjeld and municipality of Karlsøy for many hundreds of years (hence the name of the municipality). The island is still the location of the historic Karlsøy Church. The name Karlsøy comes from the man's name Kalfr which comes from Kalven, formerly meaning "the little island which lies next to the bigger one" (referring to Vannøya).
Flip Animation Festival
FLIP was an animation festival that took place between 2004 and 2012, primarily hosted by the Light House Media Centre in Wolverhampton, UK. FLIP took place annually at the beginning of November and attracted submissions from more than 30 countries worldwide. As well as screening selected submissions, FLIP held talks from professionals from the animation world, workshops, industry panels and competitions. Between 2004 and 2011 the festival was set up and managed by Peter McLuskie. It grew out of the 'Animation Forum', also based at Light House, later rebranded as Animation Forum West Midlands, which found a home at Birmingham City University. In 2009, the festival was awarded a Black Country Tourism Award for Event of the Year.

Light House Media Centre
Light House Media Centre, often simply referred to as Light House, was an independent cinema, gallery and media hub located within the historic Chubb Building, the former Chubb Locks Factory, in Wolverhampton city centre. It closed in November 2022, after operating for over 35 years. The venue reopened in July 2025 as the Lockworks Cinema.

Light House was a non-profit making organisation largely funded and supported by regional and national media orientated sources. These included the Arts Council West Midlands, Wolverhampton City Council, UK Film Council, Screen West Midlands, Skillset, Advantage West Midlands, University of Wolverhampton and Europa Cinemas Network. It was supported to develop its media education activity as an Education Hub with funds from The National Lottery through the UK Film Council.
Jeff Smith (darts player)
Jeff Smith (born 6 November 1975) is a Canadian professional darts player who competes in World Darts Federation (WDF) events. He reached the final of the 2016 BDO World Championship, where he finished as runner-up to Scott Waites. He also reached the final of the 2025 WDF World Masters, finishing as runner-up to Jimmy van Schie.

2016 BDO World Darts Championship
The 2016 BDO World Darts Championship (known for sponsorship reasons as the 2016 Lakeside World Professional Darts Championship) was the 39th World Championship organised by the British Darts Organisation, and the 31st staging at the Lakeside Country Club at Frimley Green.

The defending men's champion was Scott Mitchell, who won his first world title in 2015, but lost in the Quarter-finals to Richard Veenstra. 2013 world champion Scott Waites won the title by defeating Jeff Smith 7–1 in the final.

Lisa Ashton was the defending women's champion, having won the previous two editions, but lost to Trina Gulliver in the Quarter-finals. Gulliver then went on to win her 10th world championship title after defeating Deta Hedman 3–2 in the final.
Kampel, Indore
Kampel is a panchayat village in the Indore block of the Indore district, Madhya Pradesh, India. It was the headquarters of a pargana in Mughal Empire before the administrative center of the region was shifted to Indore city under the Holkars of the Maratha Empire.

House of Holkar
The Holkars (pronunciation: [ɦo(ː)ɭkəɾ]) were the ruling house of the Indore State of the Maratha Confederacy, and earlier held the rank of Subahdar under Peshwa Baji Rao I of the Maratha Empire. When the Maratha Confederacy began to weaken due to internal clashes, the Holkars declared themselves the rulers of Indore in Central India, existing as an autonomous member of the Maratha Confederacy until 1818. Later, their kingdom became a princely state under the British protection.

Usha Devi Holkar, 15th Maharani of Indore, is the current titular head.
Charlie Siringo
Charles Angelo Sartana Siringo (February 7, 1855 – October 18, 1928) was an American lawman, detective, bounty hunter, and agent for the Pinkerton National Detective Agency during the late 19th and early 20th centuries.

James McParland
James McParland (né McParlan; 22 March 1844 – 18 May 1919) was an Irish-American private detective and Pinkerton agent.

McParland arrived in New York in 1867. He worked as a laborer, policeman and then in Chicago as a liquor store owner until the Great Chicago Fire of 1871 destroyed his business. He then became a private detective and labor spy, noted for his success against coal mining labor organizations in Pennsylvania.
Cabinet (European Commission)
In the European Commission, a cabinet (the French pronunciation, cab-ee-nay, is used) is the personal office of a European Commissioner. The role of a cabinet is to give political guidance to its Commissioner.   Technical policy preparation is handled by the European Civil Service. The term is not to be confused with the European Commission's top decision making-body known in EU-lexicon, as the "College of Commissioners" (referred to in most political systems as a cabinet).

European Civil Service
The European Civil Service is a generic term applied to all staff serving the institutions and agencies of the European Union (EU). Although recruitment is sometimes done jointly, each institution is responsible for its own internal structures and hierarchies.
Jackson Lake Dam
Jackson Lake Dam is a concrete and earth-fill dam in the western United States, at the outlet of Jackson Lake in northwestern Wyoming. The lake and dam are situated within Grand Teton National Park in Teton County. The Snake River emerges from the dam and flows about eight hundred miles (1,300 km) through Wyoming, Idaho, Oregon, and Washington to its mouth on the Columbia River in eastern Washington.

The chief purpose of the dam is to provide water storage for irrigation in the Snake River basin in the state of Idaho as part of the Minidoka Project. Jackson Lake is a natural lake, but its depth was increased by the dam to provide water storage.

Minidoka Project
The Minidoka Project is a series of public works by the U.S. Bureau of Reclamation to control the flow of the Snake River in Wyoming and Idaho, supplying irrigation water to farmlands in Idaho. One of the oldest Bureau of Reclamation projects in the United States, the project involves a series of dams and canals intended to store, regulate and distribute the waters of the Snake, with electric power generation as a byproduct. The water irrigates more than a million acres (4,000 km²) of otherwise arid land, producing much of Idaho's potato crop. Other crops include alfalfa, fruit and sugar beets. The primary irrigation district lies between Ashton in eastern Idaho and Bliss in the southwestern corner of the state. Five main reservoirs collect water, distributing it through 1,600 miles (2,600 km) of canals and 4,000 miles (6,400 km) of lateral distribution ditches.