hotchpotch/wikipedia-multilingual-ir-related-lead-pairs huggingface dataset:
Vepdegestrant
Vepdegestrant (developmental code name ARV-471) is an investigational oral proteolysis-targeting chimera (PROTAC) compound that targets the estrogen receptor for protein degradation. It is being developed for the treatment of estrogen receptor-positive, HER2-negative (ER+/HER2-) breast cancer by Arvinas and Pfizer.

Proteolysis targeting chimera
A proteolysis targeting chimera (PROTAC) is a molecule that can remove specific unwanted proteins. Rather than acting as a conventional enzyme inhibitor, a PROTAC works by inducing selective intracellular proteolysis. A heterobifunctional molecule with two active domains and a linker, PROTACs consist of two covalently linked protein-binding molecules: one capable of engaging an E3 ubiquitin ligase, and another that binds to a target protein. Recruitment of the E3 ligase to the target results in ubiquitination and subsequent degradation of the target protein via the proteasome. Because PROTACs need only to bind their targets with high selectivity (rather than inhibit the target protein's enzymatic activity), efforts are underway to retool previously ineffective inhibitor molecules as PROTACs.
1991 AFL finals series
The 1991 Australian Football League finals series was the 95th annual edition of the VFL/AFL final series, the Australian rules football play-off tournament staged to determine the winner of the 1991 AFL Premiership season. The series ran over four weekends in September 1991, culminating with the 1991 AFL Grand Final at Waverley Park on 28 September 1991.

The McIntyre final five system, which had operated from 1972 until 1990, was replaced by the first McIntyre final six system. The following season, it was replaced by the second McIntyre final six system.

1991 AFL season
The 1991 AFL season was the 95th season of the Australian Football League (AFL), which was known previously as the Victorian Football League until 1989. The season ran from 22 March until 28 September, and comprised a 22-game home-and-away season followed by a finals series featuring the top six clubs, an increase from the top five clubs which had contested the finals since 1972.

The season saw expansion of the league to fifteen clubs, with the admission of the newly established Adelaide Crows, based in Adelaide, South Australia. With at least one team representing each of the three major Australian rules football states, the league was now the highest level senior Australian rules football competition across Australia, as well as the top administrative body for football in Victoria.

The premiership was won by the Hawthorn Football Club for the ninth time, after defeating West Coast by 53 points in the 1991 AFL Grand Final.
Ageusia
Ageusia (from negative prefix a- and Ancient Greek γεῦσις geûsis 'taste') is the loss of taste functions of the tongue, particularly the inability to detect sweetness, sourness, bitterness, saltiness, and umami (meaning 'savory taste'). It is sometimes confused with anosmia – a loss of the sense of smell. True ageusia is relatively rare compared to hypogeusia – a partial loss of taste – and dysgeusia – a distortion or alteration of taste.

Even though ageusia is considered relatively rare it can impact individuals of any age or demographic. There has been an increase in reported cases of ageusia, due to the COVID-19 pandemic making ageusia more commonly diagnosed than before.

Hypogeusia
Hypogeusia can be defined as the reduced ability to taste things. Due to a lack of stratification, the prevalence of hypogeusia, as well as hyposmia, may not be accurately known. Additionally, reviews do not always make distinctions between ageusia and hypogeusia, often classifying them as the same in certain circumstances and studies. The severity of the loss of taste from hypogeusia is not clearly outlined in current research due to these reasons.
Kia EV2
The Kia EV2 is a battery electric small hatchback from Kia. It was officially unveiled at the Brussels Motor Show on January 9, 2026. It is the sixth model in the manufacturer's "EV" battery electric car line-up after the EV4. It will launch in early 2026 and will be produced in Žilina, Slovakia.

Kia EV4
The Kia EV4 (Korean: 기아 EV4) is a battery electric compact car produced by Kia. It will be the fifth model in the manufacturer's "EV" electric car line-up after the EV3 and be offered as a hatchback and sedan.

It was first introduced on 17 February 2025, and it was fully introduced on 27 February 2025 alongside EV2 and PV5.
Diocese of the Great Lakes (UECNA)
The Diocese of the Great Lakes (DGL) was founded as a Continuing Anglican church body in the United States and Canada. More recently, it became a diocese of the United Episcopal Church of North America. Its worship centers and clergy are located in Michigan and New York.

The DGL uses the 1928 American Book of Common Prayer or the 1962 Canadian book, accepts the Holy Scriptures as the inerrant Word of God, adheres to the Thirty-nine Articles of Religion, and ordains only men to the orders of deacon, priest, and bishop. The Thirty-nine Articles are affirmed in their original sense and it is declared that Scripture contains all that is necessary to salvation. The diocese considers itself to be Evangelical Anglican and in the classical Anglican tradition.  An active work is conducted in nursing homes by DGL clergy and lay readers.

United Episcopal Church of North America
The United Episcopal Church of North America (UECNA) is a church in the Anglican tradition and is part of the Continuing Anglican movement. It is not part of the Anglican Communion.

The UECNA describes itself as "embracing the broad base of ceremonial practice inherent in the Historic Anglican Communion" although historically the UECNA has tended to be low or broad church in its ceremonial practice. The UECNA uses the 1928 American Book of Common Prayer and 1662 English prayer book in the US and, in Canada, the 1962 Canadian prayer book and 1662 prayer book.

The changes in the Episcopal Church and the Anglican Church of Canada that the UECNA and other continuing churches objected to include the theology of the newer liturgies such as the Episcopal Church's 1979 prayer book, the ordination of women, attitudes toward divorce and abortion, and differing interpretations of how the authority of scripture is perceived.
Wrexham Library
Wrexham Library (Welsh: Llyfrgell Wrecsam) is the main public library of Wrexham, Wales. Located in the city centre, adjacent to Llwyn Isaf, it opened in 1972, superseding the old carnegie library on Queen's Square.

It is the most visited library in North Wales, receiving 100,000 in-person and digital visitors annually.

Old Library, Wrexham
The Old Library (sometimes Old Carnegie Library) is a building on Queen's Square in Wrexham city centre, Wales. Built as a carnegie library in 1907, the building served as Wrexham's public library until 1973, when it later became council offices. The building is Grade II listed and owned by Wrexham County Borough Council. Since 2025, it now serves as a hub for the creative arts.
Harshagupta (ruler)
Harshagupta was a ruler of the Panduvamshi dynasty of Dakshina Kosala, who ruled Dakshina Kosala in present-day Chhattisgarh and some other parts. The famous Laxman temple at Sirpur was built by his widow Vasata in his memory.

Panduvamshis of Dakshina Kosala
The Panduvamshis (IAST: Pāṇḍuvaṁśī) or Pandavas (IAST: Pāṇḍava) were an Indian dynasty that ruled the historical Dakshina Kosala region in present-day Chhattisgarh state of India, during the 7th and the 8th centuries. They may have been related to the earlier Panduvamshis of Mekala: both dynasties claimed lunar lineage and descent from the legendary Pandavas.

After the fall of the Sharabhapuriyas in the late 6th century, Dakshina Kosala appears to have been controlled by petty chiefs until the Panduvamshis gained control of the region. The Panduvamshis may have captured a part of the neighbouring Utkala and Vidarbha regions at different times, but their control of these regions did not last long.

Their capital was probably located at Shripura (modern Sirpur). The later Somavamshi dynasty, which claimed lunar lineage, appears to have been related to them, but this cannot be said with certainty.
Albert Tissandier
Albert Tissandier (1839 – 5 September 1906) was a French architect, aviator, illustrator, editor and archaeologist. He was the brother of adventurer Gaston Tissandier with whom he collaborated in writing the magazine La Nature, a French language scientific journal aimed at the popularization of science. He and his brother demonstrated the first electric powered flight.

Gaston Tissandier
Gaston Tissandier (November 21, 1843 – August 30, 1899) was a French chemist, meteorologist, aviator, and editor. He founded and edited the scientific magazine La Nature and wrote several books.

His brother was illustrator Albert Tissandier. His son Paul became a well known aviator in his own right.
Upper Harz Ditches
The Upper Harz Ditches (German: Oberharzer Gräben, pronounced [ˌoːbɐhaːɐ̯tsɐ ˈɡʁɛːbm̩]) are hillside ditches, running roughly parallel to the contour lines, that were laid out in the Upper Harz in Germany from the 16th to the 19th centuries to supply water power to the silver mines there. They are an important component of the Upper Harz Water Regale, a historical water system that is now a cultural monument.

Kunstgraben
A Kunstgraben is a type of man-made water channel that was once used by mines to drive the water wheels needed for power, mine drainage and a host of other purposes. The term is German (plural: Kunstgräben). Similar ditches supplying water mills in England are called leats.
Gino Esposito
Gino Esposito is a fictional character from the Australian soap opera Neighbours, played by Shane McNamara. The character made his first appearance during the episode broadcast on 11 August 2000. The character was originally played by Claude Stevens. McNamara was cast in the role when the character was reintroduced in 2001. Gino owned a hair salon called A Good Hair Day, which employed both Lyn Scully (Janet Andrewartha) and Janelle Timmins (Nell Feeney). Script producer Luke Devenish called Gino "a [gay] stereotype" and a comedic character, similar to Mr. Humphries from the British sitcom Are You Being Served?. He last appeared on 27 June 2007, before returning as a new resident of the Eirini Rising retirement community on 19 September 2024. The character was added to the show's opening titles on 15 April 2025. Gino made his final appearance on 5 November 2025, shortly before the show's conclusion.

Lyn Scully
Lyn Scully is a fictional character from the Australian soap opera Neighbours, played by Janet Andrewartha. The character made her first screen appearance during the episode broadcast on 20 October 1999, along with her family and remained a prominent feature within the show until late 2006. Andrewartha reprised her role for a brief return in 2008 and then returned permanently in August 2009. Lyn departed again on 26 May 2011, so Andrewartha could pursue new acting opportunities. She reprised the role again in 2016, 2017 and 2019.
Warren Vaché Jr.
Warren Vaché Jr. (born February 21, 1951) is an American jazz trumpeter, cornetist, and flugelhornist. He came from a musical family as his father was a bassist. In 1976, he released his first album. He has often worked with Scott Hamilton and has some popularity among swing audiences.

Born and raised in Rahway, New Jersey, Vaché graduated from Rahway High School, where he played in the marching band.

Warren Vaché's father is Warren Vaché Sr., who was a jazz double-bassist. His brother Allan Vaché is also a musician.

Scott Hamilton (musician)
Scott Hamilton (born September 12, 1954) is an American jazz tenor saxophonist associated with swing and straight-ahead jazz. His eldest son, Shō Īmura, is the vocalist of the Japanese rock band Okamoto's.
Icecast
Icecast is a streaming media project released as free software maintained by the Xiph.Org Foundation. It also refers specifically to the server program which is part of the project. Icecast was created in December 1998/January 1999 by Jack Moffitt and Barath Raghavan to provide an open-source audio streaming server that anyone could modify, use, and tinker with.  Version 2, a ground-up rewrite aimed at multi-format support (initially targeting Ogg Vorbis) and scalability, was started in 2001 and released in January 2004.

Vorbis
Vorbis is a free and open-source software project headed by the Xiph.Org Foundation. The project produces an audio coding format and software reference encoder/decoder (codec) for lossy audio compression, libvorbis. Vorbis is most commonly used in conjunction with the Ogg container format and it is therefore often referred to as Ogg Vorbis.

Version 1.0 of Vorbis was released in May 2000. Since 2013, the Xiph.Org Foundation has stated that the use of Vorbis should be deprecated in favor of the Opus codec, an improved and more efficient format that has also been developed by Xiph.Org.
St Patrick's Cathedral, Toowoomba
St Patrick's Cathedral is a heritage-listed Roman Catholic cathedral on James Street, South Toowoomba, Toowoomba, Toowoomba Region, Queensland, Australia. It was designed by Toowoomba architect James Marks and was built from 1883 to 1935. The site of the cathedral was originally a church and school known as St Patrick's Church School. In 1899, the school was moved to make way for the building of the cathedral and in 1959 renamed as St Saviour's School. St Patrick's Cathedral was added to the Queensland Heritage Register on 21 October 1992.

The cathedral serves as the seat for the Bishop of Toowoomba, currently Kenneth Howell.

Diocese of Toowoomba
The Roman Catholic Diocese of Toowoomba: is a suffragan diocese of the Archdiocese of Brisbane, established in 1929, covering the Darling Downs and south west regions of Queensland, Australia.

St Patrick's Cathedral is the seat of the Catholic Bishop of Toowoomba. The diocese covers an area of 487,000 square kilometres (188,000 sq mi). with 48 priests and 57 members of religious orders.  There are 77,400 Catholics among the 276,700 total population within the diocese's borders.
Santa Clara River (California)
The Santa Clara River (Spanish: Río Santa Clara) is an 83 mi (134 km) long river in Ventura and  Los Angeles counties in Southern California. It drains parts of four ranges in the Transverse Ranges System north and northwest of Los Angeles, then flows west onto the Oxnard Plain and into the Santa Barbara Channel of the Pacific Ocean.

The watershed has provided habitat for a wide array of native plants and animals and has historically supplied humans with water, fish, and fertile farmland. The northern portion of the watershed was home to the Tataviam people while the southern portion was occupied by the Chumash people. Much of the Santa Clara River Valley is used for agriculture which has limited the use of structural levees to separate the natural floodplain from the river. Although it is one of the least altered rivers in Southern California, some levees exist where the river flows through areas of significant urban development.

Santa Clara River Valley
The Santa Clara River Valley is a rural, mainly agricultural valley in Ventura County, California that has been given the moniker Heritage Valley by the namesake tourism bureau. The valley includes the communities of Santa Paula, Fillmore, Piru and the national historic landmark of Rancho Camulos. Named for the Santa Clara River, which winds through the valley before emptying into the Pacific Ocean between the cities of Ventura and Oxnard, the tourist bureau describes it as "Southern California's last pristine agricultural valley nestled along the banks of the free-flowing Santa Clara River."
Peria Jerry
Peria Edward Jerry (/pəˈreɪ/; born August 23, 1984) is an American former professional football player who was a defensive tackle in the National Football League (NFL). He was selected by the Atlanta Falcons in the first round of the 2009 NFL draft. He played college football for the University of Mississippi. Jerry retired from football in 2014 after five seasons with the Falcons. He is the older brother of former offensive guard John Jerry.

John Jerry
John Jerry (born June 14, 1986) is an American former professional football player who was a guard in the National Football League (NFL). He played college football for the Ole Miss Rebels and was selected by the Miami Dolphins in the third round of the 2010 NFL draft. He also played for the New York Giants and Cincinnati Bengals.
GamePlan (play)
GamePlan is a 2001 play by British playwright Alan Ayckbourn, the first in a trilogy of plays called Damsels in Distress (FlatSpin and RolePlay being parts two and three.) The darkest of the three plays, it is about a teenage girl who tries to support herself and her mother through prostitution.

RolePlay (play)
RolePlay is a 2001 play by British playwright Alan Ayckbourn, the third in a trilogy of plays called Damsels in Distress (GamePlan and FlatSpin being parts one and two). It is about an engaged couple, Julie-Ann Jobson and Justin Lazenby whose engagement party is interrupted by unexpected intrusions.
General Electric F404
The General Electric F404 and F412 are a family of afterburning turbofan engines in the 10,500–19,000 lbf (47–85 kN) class (static thrust). The series is produced by GE Aerospace. Partners include Volvo Aero, which builds the RM12 variant. The F404 was developed into the larger F414 turbofan, as well as the experimental GE36 civil propfan.

Volvo RM12
Reaktionsmotor 12 (RM12) is a low-bypass afterburning turbofan jet engine developed for the Saab JAS 39 Gripen fighter. A version of the General Electric F404, the RM12 was produced by Volvo Aero (now GKN Aerospace Engine Systems). The last of the 254 engines was produced on 24 May 2011, at which time it had reached 160,000 flight hours without any serious incidents.
Durum wheat
Durum (/ˈdjʊərəm/), also called pasta wheat or macaroni wheat (Triticum durum or Triticum turgidum subsp. durum), is a tetraploid species of wheat. It is the second-most cultivated species of wheat after common wheat, although it represents only 5 to 8% of global wheat production. It was developed by artificial selection of the domesticated emmer wheat strains formerly grown in Central Europe and the Near East around 7000 BC, which developed a naked, free-threshing form. Like emmer, durum is awned (with bristles). It is the predominant wheat grown in the Middle East.

Common wheat
Common wheat (Triticum aestivum), also known as bread wheat, is a cultivated wheat species. About 95% of wheat produced worldwide is this species; it is the most widely planted of all crops by area (as of 2009) and the cereal with the highest monetary yield.
Battle of Ilorin
The Battle of Ilorin, sometimes called the Eleduwe War, occurred during the 1830s as part of the Yoruba Wars. The Ilorin Emirate's decisive victory over the invading Oyo Empire, and the death of the Alaafin Oluewu, marked the final collapse of the Oyo state.

Ilorin Emirate
The Ilorin Emirate is a traditional state based in the city of Ilorin in Kwara State, Nigeria. It is largely populated by the Yoruba-speaking people, though the kingdom is a hybrid state due to the influence of the many other tribes that make up the city.
T2 road (Zambia)
The T2 is a trunk road in Zambia. The road runs from the Tunduma border with Tanzania via Mpika, Kabwe and Lusaka to the Chirundu border with Zimbabwe. The road is the longest route of the country, as it is approximately 1,155 kilometres (718 mi). The route from Nakonde to Kafue is a toll road. The route from Tanzania to Lusaka is Zambia's Great North Road and is part of the Tanzam Highway.

For its entire route, the T2 is part of the Cape to Cairo Road. Also, the section from the T3 road junction in Kapiri Mposhi to the T1 road  junction just after Kafue is part of the Walvis Bay-Ndola-Lubumbashi Development Road.

Lusaka–Livingstone Road
The T1 or Lusaka–Livingstone Road is the main highway of the Southern Province of Zambia. It begins 55 kilometres south of the city of Lusaka (10 kilometres south of Kafue) and heads south-west to the principal tourist destination, Victoria Falls in Livingstone, via Mazabuka, Monze, Choma and Kalomo, measuring approximately 430 kilometres (267 mi). The entire route is part of Trans-African Highway network number 4 or Cairo-Cape Town Highway between Cairo and Cape Town.
RhythmOne
RhythmOne plc, a subsidiary of Nexxen, is an American digital advertising technology company that owns and operates the web properties AllMusic, AllMovie, and SideReel.

Blinkx was founded in 2004, went public on the AIM market of the London Stock Exchange in 2007, and began trading as RhythmOne in 2017. The company is headquartered in San Francisco and London, England. RhythmOne acquired All Media Network and its portfolio of web properties in April 2015. In April 2019, RhythmOne merged with Taptica International (renamed Tremor International in June 2019), an advertising technology company headquartered in Tel Aviv, Israel.

Nexxen
Nexxen (formerly Tremor International Ltd.) is a New York-based, publicly traded online advertising company. Founded in 2007, it focuses on digital advertising, including video, mobile, native advertising, and display technology and connected TV. Its stock trades on both the Nasdaq and London Stock Exchange under the ticker symbol NEXN. The company employs over 800 people across 19 offices globally.
Lu Huaishen
Lu Huaishen (Chinese: 盧懷慎; died December 11, 716), posthumous name Count Wencheng of Yuyang (魚陽文成伯), was an official of the Tang and Wu Zhou dynasties of China. He served as a chancellor during the reign of Emperor Xuanzong. He was known for his honesty as an official, but was criticized both in his time and posterity for not making decisions of his own and simply yielding to his colleague Yao Chong.

Yao Chong
Yao Chong (Chinese: 姚崇; pinyin: Yáo Chóng; 650 – September 28, 721), born Yao Yuanchong (姚元崇), known 700s–713 by the courtesy name Yuanzhi (元之), posthumous name Duke Wenxian of Liang (梁文獻公), was an official of the China's Tang and Wu Zhou dynasties, serving as chancellor under four sovereigns—Wu Zetian, her sons Emperor Zhongzong and Emperor Ruizong, and her grandson Emperor Xuanzong. After his resignation in 716, he still had great influence inside the imperial government, and his opinions often influenced the decisions of Emperor Xuanzong and the succeeding chancellors.
Jim Hazelton
James David Hazelton (20 June 1931 – 10 June 2014) was an Australian aviator and co-founder, alongside his brother Max, of Hazelton Airlines, a regional Australian airline which later became Regional Express Airlines.

In 1964 he became  the first Australian to fly a single-engine aircraft solo across the Pacific, piloting a Piper Comanche 400, a crossing he would repeat over 200 times.

Max Hazelton
Charles Maxwell Hazelton AM OBE (6 May 1927 – 9 April 2023) was an Australian aviator and founder of Hazelton Airlines, alongside his brother Jim, a regional Australian airline which became Regional Express Airlines after a merger in August 2002.