上田実 (医学研究者) 研究業績
Izumoto-Akita T, Tsunekawa S, Yamamoto A, Uenishi E, Ishikawa K, Ogata H, Iida A, Ikeniwa M, Hosokawa K, Niwa Y, Maekawa R, Yamauchi Y, Seino Y, Hamada Y, Hibi H, Arima H, Ueda M, Oiso Y.Secreted factors from dental pulp stem cells improve glucose intolerance in streptozotocin-induced diabetic mice by increasing pancreatic β-cell function.BMJ Open Diabetes Res Care. 3(1):e000128, 2015
Hattori Y, Kim H, Tsuboi N, Yamamoto A, Akiyama S, Shi Y, Katsuno T, Kosugi T, Ueda M, Matsuo S, Maruyama S.Therapeutic Potential of Stem Cells from Human Exfoliated Deciduous Teeth in Models of Acute Kidney Injury.PLoS One. 10(10):e0140121, 2015
Yamaguchi S, Shibata R, Yamamoto N, Nishikawa M, Hibi H, Tanigawa T, Ueda M, Murohara T, Yamamoto A.Dental pulp-derived stem cell conditioned medium reduces cardiac injury following ischemia-reperfusion.Sci Rep. 5:16295, 2015
Hattori Y, Kim H, Tsuboi N, Yamamoto A, Akiyama S, Shi Y, Katsuno T, Kosugi T, Ueda M, Matsuo S, Maruyama S.Correction: Therapeutic Potential of Stem Cells from Human Exfoliated Deciduous Teeth in Models of Acute Kidney Injury.PLoS One. 10(11):e0143561, 2015
（2016年〜）
Ishikawa J, Takahashi N, Matsumoto T, Yoshioka Y, Yamamoto N, Nishikawa M, Hibi H, Ishigro N, Ueda M, Furukawa K, Yamamoto A.Factors secreted from dental pulp stem cells show multifaceted benefits for treating experimental rheumatoid arthritis.Bone. 83:210-219, 2016
Shimojima C, Takeuchi H, Jin S, Parajuli B, Hattori H, Suzumura A, Hibi H, Ueda M, Yamamoto A.Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis.J Immunol. 196(10):4164-71, 2016
Hirata M, Ishigami M, Matsushita Y, Ito T, Hattori H, Hibi H, Goto H, Ueda M, Yamamoto A.Multifaceted Therapeutic Benefits of Factors Derived From Dental Pulp Stem Cells for Mouse Liver Fibrosis.Stem Cells Transl Med.5(10):1416-1424, 2016
Hishida S, Ozaki N, Honda T, Shigetomi T, Ueda M, Hibi H, Sugiura Y.Atrophy of submandibular gland by the duct ligation and a blockade of SP receptor in rats.Nagoya J Med Sci.78(2):215-27, 2016
（2017年〜）
Fujio M, Xing Z, Sharabi N, Xue Y, Yamamoto A, Hibi H, Ueda M, Fristad I, Mustafa K.Conditioned media from hypoxic-cultured human dental pulp cells promotes bone healing during distraction osteogenesis.J Tissue Eng Regen Med. 11(7):2116-2126, 2017
Al-Sharabi N, Mustafa M, Ueda M, Xue Y, Mustafa K, Fristad I.Conditioned medium from human bone marrow stromal cells attenuates initial inflammatory reactions in dental pulp tissue.Dent Traumatol. 33(1):19-26, 2017
Kano F, Matsubara K, Ueda M, Hibi H, Yamamoto A.Secreted Ectodomain of Sialic Acid-Binding Ig-Like Lectin-9 and Monocyte Chemoattractant Protein-1 Synergistically Regenerate Transected Rat Peripheral Nerves by Altering Macrophage Polarity.Stem Cells. 35(3):641-653, 2017
Ito T, Ishigami M, Matsushita Y, Hirata M, Matsubara K, Ishikawa T, Hibi H, Ueda M, Hirooka Y, Goto H, Yamamoto A.Secreted Ectodomain of SIGLEC-9 and MCP-1 Synergistically Improve Acute Liver Failure in Rats by Altering Macrophage Polarity.Sci Rep. 7:44043, 2017
（2022年〜）
Neurology and Neurorehabilitation 2022, Vol. 4, Issue 2, 011-015 The First in Human Case of Amyotrophic Lateral Sclerosis Treated with Stem Cell-Derived Conditioned Medium: A 1-Year- Follow Up Minoru Ueda1,2* and Yasuhiro Seta3  1Department of Medicine, Postgraduate School of Medicine, Emeritus of Nagoya University, Nagoya, Japan 2President of SAISEIKEN Co. LTD, Tokyo, Japan  3Director of Smart Clinic Tokyo, Tokyo, Japan
Special Lecture in Honor of Opening Ceremony of Newly Constructed Hospital of the Korea University (1991.6.22 Seoul, Korea) Ueda M Osseointegrated implant for maxillofacial reconstructive surgery.
International Symposium on Wound Healing and Tissue Regeneration (1995.2.22-24 Hiroshima, Japan) Ueda M, Hata K, Takahashi K. Cell kinetic analysis of wound contraction using connective tissue model and computer simulation.
Academy of Osseointegration 10th Annual Meeting (1995.3.2-4 Chicago, U.S.A.) Ueda M, Ohkubo H, Yamamoto H, Sawaki Y. Mandibular lengthening by intraoral distraction using osseointegrated implants.
Brånemark System 30 Year Anniversary (1995.8.17-19 Gothenburg, Sweden) Ueda M, Ohkubo H, Hibi H, Sawaki Y. Mandibular lengthening by distraction osteogenesis using osseointegrated implants and an intraoral device Ueda M, Hata K, Murakami I, Niimi A. Vestibloplasty for implant therapy using cultured mucosal epithelium.
Academy of Osseointegration 11th Annual Meeting (1996.2.29-3.2 New York, U.S.A.) Ueda M, Sawai Y, Ohkubo H, Yamamoto H. Osteomorphous control of craniofacial skelton by distraction osteogenesis using osseointegrated implants.
International Congress on Cranial and Facial Bone Distraction Processes (1997.6.20-21 Paris, France) Ueda M. Maxillofacial bone distraction processes using osseointegrated implant and intraoral device.
13th International Conference on Oral and Maxillofacial Surgery (1997.10.20-24 Tokyo, Japan)Ueda M. Osteomorphous control by distraction osteogenesis using osseointegrated implant in maxillofacial region.
13th Annual Meeting of Academy of Osseointegration (1998.3.5-7 Atlanta, U.S.A.) Ueda M, Sawaki Y, Oda T. Ridge augmentation by distraction osteogenesis using osseointegrated implants.
Association for Dental Science of the Republic of China (1998.4.10-12 Taiwan)Ueda M. The effect of teeth loss on spatial memory and acetylcholine release from the parietal cortex in aged rats.
1st Craniofacial Distraction Osteogenesis (1998.11.18-22 Malaysia) Ueda M. Osteomorphous control by distraction osteogenesis using osseointegrated implants Ueda M.A pilot of motor driven distraction device for mandibular reconstruction.
The20th Annual conference of the America College of Oral and Maxillofacial Surgery (1999.2.25-28 Orland, U.S.A.) Ueda M. Biology of distruction osteogenesis using osseointegrated implant.
The 3rd International Symposium on Tissue Engirneering (2001.6.1 Seoul, Korea) Ueda M. Tissue engineering in oral surgery and recent advances in Japanese Tissue Engineering Society.
Second International Symposium on Biomimetic Materials Processing (2002.1.15-17 Nagoya, Japan) Ueda M. Strategy for maxillofacial bone regeneration using tissue engineering concept.
29th Annual Meeting and Exposition of the Controlled Release Society (2002.7.22-25 Seoul, Korea) Ueda M. Strategy for maxillofacial bone reconstraction using tissue engineering concept.
Academy of Osseointegration 18th Annual Meeting (2003.2.27-3.1 Boston, U.S.A.) Ueda M, Yamada Y, Ito K, Okazaki Y. Tissue engineered bone using mesenchymal stem cells and platelet-rich plasma.
5th Annual Meeting of Korean Tissue Engineering Society and 1st Korea-Japan Joint Symposium (2003.5.24 Seoul, Korea) Ueda M. Tissue-engineered bone applied for implant surgery and its commercialization.
2004 Korea Congress of Oral & Maxillofacial Surgery (2004.4.22-24 Seoul, Korea) Ueda M. Tissue-engineered bone applied for alveolar ridge augmentation with simultaneous implant placement.
International Conference on Biomaterials and Tissue Engineering 2004 (2004.5.24-26 Kuala Lumpur, Malaysia) Ueda M. Tissue-engineered bone applied for alveolar ridge augmentation with simultaneous implant placement.
Jeddah International Dental Congress (2008.11.3-5 Saudi Arabia) Ueda M. Part 1: Tissue Engineering and Anti-aging in Dentistry. Part 2: The future possibilities of teeth pulp stem cell for tissue engineering therapy.
The World Gene Convention ( 2016. 10.19 Shanghai )[ Plenary Lecture ] Ueda M.The First in Human Study of Diabetes Type II with the Conditioned Medium from Stem Cell of Human Exfoliated Deciduous Teeth.
Joint Work Shop Between Norway and Japan in Regenerative Medicine ( 2018.6.4 Tokyo )[ Key Note Speech ]Regenerative Medicine by Mesenchymal Stem CellUeda,M [ Symposium Session 2. Central Nerve Regeneration ]Functionary Recovery of Alzheimer’s Disease Using Stem Cells from Human Exfoliated Deciduous Tooth-Derived Conditioned Medium.Ueda M.
（1999年〜）
Ohno K, Takahashi T, Maki K, Ueda M, Taguchi O.Successful transfer of localized autoimmunity with positively selected CD4+ cells to scid mice lacking functional B cells.Autoimmunity. 29: 103-10, 1999
Nishigaki-Maki K, Takahashi T, Ohno K, Morimoto T, Ikeda H, Takeuchi M, Ueda M, Taguchi O. Autoimmune diseases developed in athymic nude mice grafted with embryonic thymus of xenogeneic origin.Eur J Immunol. 29: 3350-9, 1999
Mizuno H, Emi N, Abe A, Takahashi I, Kojima T, Saito H, Sumi Y, Hata KI, Ueda M.Successful culture and sustainability in vivo of gene-modiﬁed human oral mucosal epithelium. Hum Gene Ther. 10: 825-30, 1999
Nakai H, Niimi A, Ueda M.Histologic evaluation of clinically successful osseointegrated implants retrieved from irradiated bone: a report of 2 patients.Int J Oral Maxillofac Implants. 14: 442-6, 1999
Yamada Y, Itano N, Narimatsu H, Kudo T, Hirohashi S, Ochiai A, Niimi A, Ueda M, Kimata K.Receptor for hyaluronan-mediated motility and CD44 expressions in colon cancer assessed by quantitative analysis using real-time reverse transcriptase-polymerase chain reaction.Jpn J Cancer Res. 90: 987-92, 1999
Su WZ, Tohnai I, Kawamura T, Tamakoshi A, Wakai K, Aoki R, Kojima M, Ueda M, Ohno Y.Trends in site-speciﬁc mortality from oral and pharyngeal cancer among Japanese males, 1950-94. Oral Oncol. 35: 9-16, 1999
Sumi Y, Nakamura Y, Mitsudoh K, Ueda M.Application of titanium-alloy endodontic implants in conjunction with periradicular surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 88: 484-7, 1999
（2000年〜）
Hiramatsu Y, Kagami H, Horie K, Okazaki Y, Shigetomi T, Hata K, Kobayashi S, Ueda M.Effects of basic ﬁbroblast growth factor on cultured rat and human submandibular salivary gland cells. Arch Oral Biol. 45: 593-9, 2000
Oda T, Sawaki Y, Ueda M.Experimental alveolar ridge augmentation by distraction osteogenesis using a simple device that permits secondary implant placement.Int J Oral Maxillofac Implants. 15: 95-102, 2000
Honda M, Yada T, Ueda M, Kimata K.Cartilage formation by cultured chondrocytes in a new scaffold made of poly(L-lactide-epsilon- caprolactone) sponge.J Oral Maxillofac Surg. 58: 767-75, 2000
Mizuno H, Emi N, Abe A, Takahashi I, Kojima T, Saito H, Matsuno M, Sumi Y, Hata K, Ueda M.An ex vivo model for gene therapy of hemophilia B using cultured humal oral mucosal epithelium. Mater Sci Eng. 13: 45-48, 2000
（2001年〜）
Hayashi Y, Iwashita T, Murakamai H, Kato Y, Kawai K, Kurokawa K, Tohnai I, Ueda M, Takahashi M. Activation of BMK1 via tyrosine 1062 in RET by GDNF and MEN2A mutation.Biochem Biophys Res Commun. 281: 682-9, 2001
Hayashi Y, Tohnai I, Yamamoto N, Fukuhara H, Fukui T, Ueda M, Mizuno M, Yoshida J.Suicide gene therapy with ganciclovir and adeno-associated virus vector containing the herpes simplex virus thymidine kinase gene for human oral squamous cell carcinoma cell lines.Dent Jpn. 37: 74-77, 2001
Matsuno H, Tohnai I, Mitsudo K, Hayashi Y, Ito M, Shinkai M, Kobayashi T, Yoshida J, Ueda M.Intersitial hyperthermia using magnetite cationic liposomes inhibit to tumor growth of VX-7 transplanted tumor in rabbit tongue.Jpn J Hyperthermic Oncol. 17: 17-26, 2001
Fukui T, Hayashi Y, Kagami H, Yamamoto N, Fukuhara H, Tohnai I, Ueda M, Mizuno M, Yoshida J.Suicide gene therapy for human oral squamous cell carcinoma cell lines with adeno-associated virus vector.Oral Oncol. 37: 211-5, 2001
Kaneko R, Tohnai I, Ueda M, Negoro M, Yoshida J, Yamada Y.Curative treatment of central hemangioma in the mandible by direct puncture and embolisation with n-butyl-cyanoacrylate (NBCA).Oral Oncol. 37: 605-8, 2001