Relevant dates include 117 CE, when the Empire was at its greatest territorial extent, and the accession of Diocletian in 284. Irreversible major territorial loss, however, began in 376 with a large - scale irruption of Goths and others. In 395, after winning two destructive civil wars, Theodosius I died, leaving a collapsing field army and the Empire, still plagued by Goths, divided between his two incapable sons. By 476 when Odoacer deposed the Emperor Romulus, the Western Roman Emperor wielded negligible military, political, or financial power and had no effective control over the scattered Western domains that could still be described as Roman. Invading barbarians had established their own power in most of the area of the Western Empire. While its legitimacy lasted for centuries longer and its cultural influence remains today, the Western Empire never had the strength to rise again.
The precise start and end of the Industrial Revolution is still debated among historians, as is the pace of economic and social changes. Eric Hobsbawm held that the Industrial Revolution began in Britain in the 1780s and was not fully felt until the 1830s or 1840s, while T.S. Ashton held that it occurred roughly between 1760 and 1830. Rapid industrialization first began in Britain, starting with mechanized spinning in the 1780s, with high rates of growth in steam power and iron production occurring after 1800. Mechanized textile production spread from Great Britain to continental Europe and the United States in the early 19th century, with important centres of textiles, iron and coal emerging in Belgium and the United States and later textiles in France.
Hiberni (Ireland), Pictish (northern Britain) and Britons (southern Britain) tribes, all speaking Insular Celtic, inhabited the islands at the beginning of the 1st millennium AD. Much of Brittonic-controlled Britain was conquered by the Roman Empire from AD 43. The first Anglo-Saxons arrived as Roman power waned in the 5th century and eventually dominated the bulk of what is now England. Viking invasions began in the 9th century, followed by more permanent settlements and political change—particularly in England. The subsequent Norman conquest of England in 1066 and the later Angevin partial conquest of Ireland from 1169 led to the imposition of a new Norman ruling elite across much of Britain and parts of Ireland. By the Late Middle Ages, Great Britain was separated into the Kingdoms of England and Scotland, while control in Ireland fluxed between Gaelic kingdoms, Hiberno-Norman lords and the English-dominated Lordship of Ireland, soon restricted only to The Pale. The 1603 Union of the Crowns, Acts of Union 1707 and Acts of Union 1800 attempted to consolidate Britain and Ireland into a single political unit, the United Kingdom of Great Britain and Ireland, with the Isle of Man and the Channel Islands remaining as Crown Dependencies. The expansion of the British Empire and migrations following the Irish Famine and Highland Clearances resulted in the distribution of the islands' population and culture throughout the world and a rapid de-population of Ireland in the second half of the 19th century. Most of Ireland seceded from the United Kingdom after the Irish War of Independence and the subsequent Anglo-Irish Treaty (1919–1922), with six counties remaining in the UK as Northern Ireland.

Question: When did the fall begin of the empire that in AD 43 conquered the country where the industrial revolution would start?
Answer: in 376