Prue, Piper, and Phoebe's relaxing night at the club is cut short when they're forced to go up against the Four Horsemen of the Apocalypse, who are causing various bouts of road rage in San Francisco. When Prue and Horseman of War are sucked into a vortex that transports them to the Netherworld of Good and Evil, Piper and Phoebe are facing a dilemma of saving Prue or save the world. While attempting to help the sisters out, Leo tries to get his bosses to aid the Charmed Ones and comes across organized evil.