In the aftermath of Izzie's affair with George, he doesn't seem to remember anything, and Izzie does her best to avoid Callie, but she becomes nervous when she has to help Callie and George treat a patient with FOP . Callie lets George know that they will be having dinner with her father, but George does not make a good impression, being hungover after last night's events. Alex helps Jane Doe choose what her face will look like after Mark performs reconstructive surgery on her. He also gives her a new perspective on how the world will see her from then on. The hospital board begins interviewing the candidates for the Chief's position, and Colin intimidates everyone with his ten-year plan. However, after taking advice from Bailey, Mark seems to have convinced the board that he is appropriate for the job, despite continuous efforts from Derek, Burke, and Addison, whose careers in the hospital outlast his. Cristina looks for a way to save a man's foot when he makes it clear that he doesn't want it amputated. Izzie seeks advice from Addison about her affair, confessing that sleeping with George felt right, despite him being married. Mark takes Meredith as his intern for the day in order to impress Webber, something that Derek doesn't approve of, feeling that Mark has become manipulative.