Stefan tries to contact Isobel and gets in touch with John Gilbert, who comes home. While Damon tries to get Jules to tell him how to cure the werewolf bite, he asks Elena to keep an eye on Rose, who becomes delirious and mistakes her for Katherine. Caroline and Matt confess their love for each other. Tyler's reaction to Caroline's generosity surprises her. Rose escapes from the Salvatore house and goes on a killing spree. Damon finds her and brings her back to the Salvatore's house, he then stakes her, while giving her a peaceful death by giving her a dream about her old home. He confesses to a stranger that he misses being human. He lets her go, but bites her soon after. Jules informs Tyler that she knows that he and Mason are werewolves. She tells him that more werewolves are coming.