This article published in Cell J (Yakhteh), Vol 23, No 2,2021, on pages 191-198, corresponding author andcorresponding address were changed based on authors’request. The authors would like to apologies for anyinconvenience caused.


Zingiber officinale var. rubrum (red ginger) is widely used in traditional medicine in Asia. Unlike other gingers, it is not used as a spice in cuisines. To date, a total of 169 chemical constituents have been reported from red ginger. The constituents include vanilloids, monoterpenes, sesquiterpenes, diterpenes, flavonoids, amino acids, etc. Red ginger has many therapeutic roles in various diseases, including inflammatory diseases, vomiting, rubella, atherosclerosis, tuberculosis, growth disorders, and cancer. Scientific evidence suggests that red ginger exhibits immunomodulatory, antihypertensive, antihyperlipidemic, antihyperuricemic, antimicrobial, and cytotoxic activities. These biological activities are the underlying causes of red ginger’s therapeutic benefits. In addition, there have been few reports on adverse side effects of red ginger. This review aims to provide insights in terms the bioactive constituents and their biosynthesis, biological activities, molecular mechanisms, pharmacokinetics, and qualitative and quantitative analysis of red ginger. Zingiber officinale, consisting of seven species, is mainly distributed in Asia , of which two are accepted names and six are synonyms. Based on the size and color of the rhizome, common ginger can be categorized into three varieties: giant ginger or white ginger , small white ginger or emprit ginger Rhizome , and red ginger  [Zingiber officinale Roscoe var. rubrum. Its synonyms are Zingiber officinale Roscoe var Sunti Val., Zingiber amomum L., Zingiber cholmondeleyi (F.M. Bailey) K. Schum., Zingiber missionis Wall., Zingiber officinale var. macrorhizonum Makino, Zingiber officinale var. rubens Makino, and Zingiber sichuanense. It is red, with a yellow to pink cross section on the outside of the rhizomes, while the base of the leaf shoot is red. It is an annual plant that grows up to 50–100 cm high. The rhizomes are thick and reddish-brown. It is morphologically similar to common ginger. It is smaller and more pungent than common ginger. The leaves are narrow and lancet-shaped, 5–25 cm in length and 8–20 mm in width. The plant has an ovoid-shaped composite that emerges from the rhizomes, with a stem length of 10–25 cm and small leaves at the base of the flower. The corollas are funnel-shaped, 2–2.5 cm long, and dark purple with creamy yellow spots. The petals are small, tubular, and tridentate. Unlike common ginger, its petiole is reddish, and the lip is scarlet red [There is a taxonomic challenge when identifying the correct species as many synonyms are reported for ginger. There are eight plant names for the species  rubrum) . Red ginrlet red . Red ginZingiber officinale var. rubrum”, “Halia Bara”, and “red ginger”. Only articles published in English are included in this review. A few additional references from the web that were deemed useful for the completion of this review article were included.The Pubmed, Scopus, and Web of Science databases were used to collect the information on red ginger. The keywords used were “Zingiber officinale var. rubrum. This review aims to provide an exhaustive summary of the (1) traditional uses, (2) chemical constituents and their biosynthesis, (3) bioactivities and molecular mechanisms, (4) analysis and quality control, and (5) medicinal products. Research gaps in the literature are identified and we have suggested future research opportunities. Perspectives on further improving the medicinal value of red ginger are provided.To the best of our knowledge, this review article is the first on The chemical composition of red ginger is complex, containing about 169 chemical constituents ,11,12,13The chemical structures of constituents and their respective compound classes are recorded in The vanilloids are biosynthesized from the amino acid phenylalanine, as shown in Red ginger is reported to possess a wide range of biological and pharmacological activities. In traditional medicine, it is used for treating headaches, indigestion, nausea, vomiting, and cancer. In addition, it is widely used to treat autoimmune diseases , hypertePseudomonas aeruginosa, Staphylococcus aureus, and Bacillus subtilis. The rhizome oil was moderately active against Bacillus licheniformis, Bacillus spizizenii, Staphylococcus aureus, and Escherichia coli [Many studies have reported the antimicrobial and antifungal effects of ethanol and methanol extracts of red ginger ,64. Red Candida albicans, Staphylococcus aureus, and Streptococcus mutans; therefore, the combinations may help treat orals infections. Another study found that the combination of nisin and red ginger essential oil had a synergistic effect against Bacillus cereus [Red ginger extract has been used as an auxiliary medicine for treating oral infections. Sukandar et al.  investigs cereus . Studiess cereus . Irawan s cereus  have incs cereus  optimizeβ-caryophyllene has predominant antimicrobial activity [Bacillus cereus > Escherichia coli > Salmonella typhimurium > Pseudomonas aeruginosa [Staphylococcus aureus > Escherichia coli > Aspergillus niger > Bacillus cereus > Pseudomonas fluorescens > Salmonella typhimurium. In contrast, the fresh red ginger extract showed stronger activity against Staphylococcus aureus and E. coli [Streptococcus mutans is more potent than that of common ginger [The primary antimicrobial compounds in red ginger are monoterpenes, of which activity . The majactivity . The antruginosa  and Stap E. coli . The antn ginger . Many st2B activity and pain sensitization [The analgesic activity of red ginger is comparable to that of aspirin . Neuropatization . Anothertization ,73. Red tization . Camphentization ,35.Red ginger inhibits saccharide hydrolyzing enzymes and, thus, can be used for controlling hyperglycemia in type 2 diabetic patients. Safithri et al.  found thOboh et al.  reportedMany studies have confirmed that chronic inflammation is the underlying cause for many diseases such as allergies, atherosclerosis, cancer, diabetes, infection, obesity, and neurodegeneration ,78. Red Many studies have confirmed red ginger’s free radical scavenging activity in different test models ,44,45. Tortho-dihydroxy group on the aromatic ring in vanilloids play a significant role in the anticancer activity [The anticancer activity of red ginger is mainly due to certain pungent vanilloids . Severalactivity . Vimala activity  reportedactivity ,47. Studactivity  reportedactivity . Multiplactivity ,50,51 (Fw/v) inhibited the actions of Angiotensin-I converting enzyme (ACE), iron(II) ion, and sodium nitroprusside (SNP)-induced lipid peroxidation in rats’ hearts via reducing malondialdehyde levels. The activity of red ginger in this respect is more remarkable than that of common ginger [2+ release from intracellular stores. The vanilloids are attributed to the antihypertensive activity of red ginger.The antihyperlipidemic, antihypertensive, and antihypercholesterolemic mechanisms of action are as shown in n ginger . The antn ginger . Razali n ginger  demonstrIt is well known that red ginger extract contains phenolic compounds, which have been shown to protect against metabolic disorders such as hypercholesterolemia. Hypercholesterolemia results from increased cholesterol levels and increased production of free radicals. Phenolic compounds reduce the risk of hypercholesterolemia by (1) increasing the activity of antioxidant enzymes, (2) decreasing the formation of free radicals, hydroxyl radicals, and superoxide anions, (3) inhibiting lipid peroxidation, and (4) regulating low-density lipoprotein (LDL) receptors .Red ginger is reported to (1) inhibit lipid peroxidation, (2) increase antioxidant enzymes, (3) regulate low-density lipoprotein (LDL) receptors, and (4) regulate 3-hydroxy-3-methylglutaryl coenzyme-A receptors (HMG-CoA), which affect cholesterol absorption in the liver ,91.Oboh et al. have reported the acetylcholinesterase (AChE) inhibitory effect of red ginger in SNP-induced mice . Red ginThe vanilloids of red ginger have a potent antioxidant effect . Yang etAedes albopictus, Aedes aegypti, and Culex quinquefasciatus. The major principal constituents in the extract were zingerone (14.92%) and benzaldehyde dimethyl thiol acetal (11.61%). Another study reported the insecticidal activity of red ginger against Spodoptera frugiperda [Mahardika et al.  reportedugiperda  via incrEscherichia coli-infected mice [E. coli strain O157 [Red ginger is usually one of the ingredients in immunomodulating supplements. A study showed that the administration of black cincau and red ginger had immunomodulatory effects in infected mice. Exposure of infected mice to red ginger and black cincau can help them to recover the small intestine mucosa structure. This study demonstrates that red ginger extract can have an immunomodulatory effect in ted mice . The comted mice . Due to ain O157 .Red ginger is one of the ingredients in Wedang uwuh . WU has antioxidant activity, can promote blood circulation, and improves immunity. WU extract administered via 27 mL/kg injections had a dose-dependent immunomodulatory potential in diabetic rats. The results showed that WU significantly inhibited the expression of pro-inflammatory cytokines and anti-inflammatory cytokines and achieved a balance between pro-inflammatory and anti-inflammatory cytokines that was not significantly different from that of normal controls. This study’s results confirm that the use of WU can result in immunomodulatory activity in diabetic rats.Yamauchi et al.  reportedGrowth conditions influence the chemistry and content of active ingredients in any plant; therefore, developing analytical methods to determine the identity and quality is essential. Two anam/z. A Waters Atlantis T3 column  was used and the column temperature was maintained at 40 °C. The mobile phase was a binary eluent of (A) 5 mM (NH4)OAc solution and (B) CH3CN under the following gradient conditions: 0–30 min, linear gradient from 10% to 100% B; 30–40 min, isocratic at 100% B. The flow rate was 0.2 mL/min.The chemical fingerprint analysis was reported using HPLC-TOF-MS. The optRed ginger has gained traction, especially in Asia, where it is known for its medicinal effects: dispelling wind from the body, relieving indigestion, improving blood circulation, and relieving inflammation. The beneficial effects attributed to the constituents of red ginger have occasioned the creation of various medicinal products. In Southeast Asia, red ginger is locally known as halia bara, halia merah, or jahe merah. Currently, the red ginger products marketed in Southeast Asia include foodstuffs such as dried ginger pieces and pickled ginger, and red ginger extracts in instant beverages such as tea and coffee. Furthermore, red ginger extracts are also added to body lotions, creams, ointments, and capsules.Our research group has avidly studied ginger, its constituents, and their pharmacological properties. We prepared this review to present a concise summary of the information on red ginger gathered from the scientific literature thus far. We believe that this will be useful to researchers who are working on ginger, natural products, functional foods, and even ethnomedicine. From our perspective, based on our experience with ginger variants, the following are the main differences between red ginger and common ginger. They are: (1) they differ in color and size; (2) fresh red ginger is more pungent than fresh common ginger; (3) upon drying, red ginger turns black, while common ginger does not; (4) dried red ginger is much harder than dried common ginger; (5) the constituents are reported to be the same in both gingers; however, red ginger is reported to be more biologically active; (6) a few studies have reported that the active constituents (gingerols and shogaols) are higher in red ginger than in common ginger; (7) it is very difficult to distinguish these two variants based on the chemical composition via simple analytical techniques using HPLC and GC instruments; (8) there have been no studies characterizing the constituent that gives red ginger its color; (9) there are no studies on why red ginger is hotter than common ginger; and (10) there are no detailed studies that compare the bioactivities of red ginger and common ginger under the same experimental conditions that clearly explain why red ginger is preferred in ethnomedicine, etc.To date, conclusions on the differences between red ginger and common ginger have yet to be drawn. We strongly believe that it is still worth scientifically exploring the effects of red ginger. The research should be carried out on a standardized extract rather than individual compounds in the physiologically relevant models and molecular mechanisms. It is well established that vanilloids are unique compounds in all ginger variants. Based on our experience with ginger, we believe that red ginger’s chemistry (both primary and secondary metabolites) is different from common ginger, giving rise to a difference in the hotness and biological activities. In our opinion, the plant preparations (consisting of active and inactive constituents) in ethnomedicine are equivalent to modern formulations  and excipients). It is well known that excipients in a formulation influence the bioactivity of API. Similarly, the inactive constituents in a plant extract also influence the bioactivity of the active constituents.https://go.drugbank.com/drugs, accessed on 20 November 2021), which indicates the potential for ginger to be used in modern medicine for therapeutic purposes.Red ginger extracts are scientifically validated for their beneficial effects in inflammatory diseases, metabolic diseases, cancer, neurological diseases, and cardiovascular diseases. Research in these disease areas is still a priority for many researchers, institutions, and the pharmaceutical industry. Thus, like herbal medicine, we argue that red ginger has a lot of potential to provide breakthroughs for these diseases. The ginger extract, ginger oil, and zingerone (pungent components of ginger) are included in DrugBank (This review summarizes the latest research progress on red ginger regarding its chemistry, ethnomedicinal uses, biological activities, molecular mechanism, and analytical methods. We have provided our perspectives on the value of red ginger in metabolic and neurological diseases. The vanilloids are unique to ginger, and are stable in ginger. However, upon isolation in pure form, they are not stable at room temperature. Although vanilloids are simple molecules, their synthesis is still challenging. Thus, further exploring the potential of red ginger in medicine is essential. Many herbal formulations containing red ginger are famous in various traditional systems of medicine. Many scientific studies worldwide have proven the efficacy of red ginger in a wide array of diseases—metabolic, neurological, cardiovascular, infectious, and cancer. Despite red ginger being relatively safe ,95, cons


Error in Institutional Review Board Statement :In the original publication, the Institutional Review Board Statement was incorrect. The authors apologize for the omission and for any inconvenience caused, and state that the scientific conclusions are unaffected. The original publication has also been updated.Corrected Institutional Review Board Statement:“The authors confirm that this study has been ethically reviewed by the Bio-Ethics Committee of the University of Turin [UOR: SI000045—Classif. III/11] under protocol number 0011298 and that ethical approval was granted in January 2012.”


Subsequently to the comments raised by the reader, the authors themselves contacted the Editorial Office to request a retraction of the above paper on account of not being to reproduce the results shown in the Oncology Reports, and in line with the authors’ own request, the Editor has decided that this paper should be retracted from the Journal. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to


The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates.


Furthermore, they regret any inconvenience that this mistake has caused.


Therefore, the affiliations for this paper should have been written as follows (changes are highlighted in bold):1*, ZHENG LI1*, GUANGMING WANG1, XIAOXUE TIAN1, JIE ZHOU1, WENLEI YU1, ZHUOYI FAN1, LIN DONG1, JINYUAN LU1, JUN XU2, WENJUN ZHANG1 and AIBIN LIANG1FANGCE WANG1Department of Hematology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200092; 2Medical Center for Stem Cell Engineering and Transformation, East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China*Contributed equallyThe authors confirm that there are no further errors in the paper, and all the authors agree to this correction. The authors and the Editor apologize for any inconvenience caused.


Entropy 2020, 22, 61”. Firstly, there was an obvious and easily corrected mathematical error at the end of Section 6 of the paper. In the Clifford algebra under consideration, the basis bivectors M does square to the identity and hence non-zero divisors of zero, Corrections are made to my paper “Gill, R.D. Does Geometric Algebra Provide a Loophole to Bell’s Theorem? ad hominem and ad verecundam arguments, a number of scientifically superfluous but insulting sentences have been deleted, and other disrespectful remarks have been rendered neutral by omission of derogatory adjectives. I would like to apologize to Dr. Joy Christian for unwarranted offence.Secondly, in response to a complaint about The end of Section 6 of Gill (2020)  discusseM squares to v. It satisfies One can take as basis for the eight-dimensional real vector space M squares to But the bivectors


After publication of this article  and ExprThe authors stated that this overlap was due to an error in figure preparation, and that the IRF1 panels are incorrect. They provide here an updated version of PLOS ONE Editors apologize that this issue was not identified prior to publication of the Expression of Concern [The  Concern .S2 FileLevel of glycoprotein expression was determined by immunofluorescence assay for the group of IRF1 and its control (pcDNA3), and the group of sh-IRF1 and its control (pSilencer).(ZIP)Click here for additional data file.


Experimental & Molecular Medicine 10.1038/s12276-018-0133-y, published online 05 September 2018Retraction to: The authors have retracted this article. After publication they repeated the experiments further increasing the expression of KCNMA1 but found that this did not activate the cGMP PKG signaling pathway. The authors now believe that the mechanism by which the KCNMA1 gene inhibits the cGMP PKG signaling pathway affecting the disease is not one-to-one regulation. All authors agree to this retraction.


The authors apologize for The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


Erratum zu:Chirurg 202110.1007/s00104-021-01364-2Der Name des Erstautors Ralf Böthig ist im ursprünglich publizierten Beitrag nicht korrekt genannt worden. Die Autoren bitten den Fehler zu entschuldigen.


This abstract has been withdrawn.


Nature Communications 10.1038/s41467-021-26743-5, published online 18 November 2021.Correction to: The HTML version of this Article incorrectly omitted Supplementary Movie 1–14. Supplementary Movie 1–14 can be found as Supplementary Information associated with this Correction.Supplementary Movie 1Supplementary Movie 2Supplementary Movie 3Supplementary Movie 4Supplementary Movie 5Supplementary Movie 6Supplementary Movie 7Supplementary Movie 8Supplementary Movie 9Supplementary Movie 10Supplementary Movie 11Supplementary Movie 12Supplementary Movie 13Supplementary Movie 14


Affordable, reliable and high-quality child and elderly care services are essential for employees to do teleworking in an efficient manner.


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Effective treatment of glioma requires a nanocarrier that can cross the blood–brain barrier (BBB) to target the tumor lesion. In the current study, elemene (ELE) and cabazitaxel (CTX) liposomes were prepared by conjugating liposomes with transferrin (Tf) and embedding the cell membrane proteins of RG2 glioma cells into liposomes , which exhibited effective BBB infiltration to target glioma.The findings showed that Tf-ELE/CTX@BLIP was highly stable. The liposomes exhibited highly significant homologous targeting and immune evasion in vitro and a 5.83-fold intake rate compared with classical liposome (ELE/CTX@LIP). Bioluminescence imaging showed increased drug accumulation in the brain and increased tumor penetration of Tf-ELE/CTX@BLIP in orthotopic glioma model nude mice. Findings from in vivo studies indicated that the antitumor effect of the Tf-ELE/CTX@BLIP led to increased survival time and decreased tumor volume in mice. The average tumor fluorescence intensity after intravenous administration of Tf-ELE/CTX@BLIP was 65.2, 12.5, 22.1, 6.6, 2.6, 1.5 times less compared with that of the control, CTX solution, ELE solution, ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP groups, respectively. Histopathological analysis showed that Tf-ELE/CTX@BLIP were less toxic compared with administration of the CTX solution.These findings indicate that the active-targeting biomimetic liposome, Tf-ELE/CTX@BLIP, is a promising nanoplatform for delivery of drugs to gliomas.The online version contains supplementary material available at 10.1186/s12951-021-01048-3. P-gp) occurs on the BBB, which further increases clearance of chemotherapy drugs  = 20 μg/mL) and incubated for 2 h. In addition, RG2 cells were seeded into a 6-well plate (3 × 105 cells/well) and incubated with ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP (Rho B = 20 μg/mL) for 2 h. The medium was removed and cells were fixed with 4% paraformaldehyde, stained with DAPI and washed thrice with PBS. The cellular uptake was determined by confocal laser scanning microscope imaging  and flow cytometry [Tf-ELE/CTX@BLIP was incubated with SPC-A-1 cells, A549 cells, MDA-MB-231 cells, LM-3 cells, U251 cells, C6 cells, and RG2 cells, separately. Cells were inoculated into 6-well plates  for 2 h. Effect on immune evasion was then determined by CLSM and flow cytometry .Cytotoxicity effects of ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP on RG2 cells were determined using a CCK-8 kit. RG2 cells (3000 cells/well) were inoculated in 96-well plates and incubated for 24 h. After incubation, cells were exposed to ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP (CTX concentrations ranging from 0.4 to 200 ng/mL) for 48 h. Non-treated cells were used as negative controls. Medium was evaluated as the blank control. Cytotoxicity was quantitatively determined by measuring the absorbance at 450 nm using a Spark multi-functional microporous plate testing platform .Furthermore, apoptotic cells were determined by FACS analysis . RG2 cells were incubated with ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP and 50 ng/mL CTX for 48 h then treated with the apoptosis detection kit  for 10 min. Percentage of apoptotic cells was determined using a FACS Calibur System. Non-treated cells were used as the negative control .5 cells/well) and incubated for 24 h. Rhodamine 123  was preconditioned with ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP, Tf-ELE/CTX@BLIP (50 ng/mL) and verapamil (0.625 μg/mL) separately for 30 min then it was exposed to bEnd.3 for 2 h. The medium was removed and bEnd.3 cells were fixed with 4% paraformaldehyde for 30 min and washed thrice with PBS. Cells were then analyzed using fluorescence microscope and flow cytometry. Relative expression level of P-gp in bEnd.3 cells was determined by WB assay. bEnd3 cells in 6-well plates were conditioned with medium and verapamil, ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP, Tf-ELE/CTX@BLIP were added [bEnd.3 cells were cultured as described in the “re added .Female nude mice  were obtained from Shanghai Slack Laboratory Animal Co. LTD. Mice were allowed to acclimatize at room temperature for 7 days prior to the performing animal studies. Animals were housed under the animal care facility and allowed free access to food/water. All animal experiments were approved by the animal ethics committee of Hangzhou Normal University .7 glioma-luc cells in medium were injected slowly into the brain right striatum of nude mice . The needle was maintained at the injection point for 1 min after injection and then pulled out slowly. Alcohol cotton swabs were used to disinfect the skin, the skin was sewn with a needle and thread. The mice were then placed back to the cage to wake up naturally. Rate of growth of intracranial tumor was monitored by magnetic resonance imaging (MRI) and fluorescence imaging.Glioma-luc cells were injected into the right striatum of nude mice to develop a orthotopic glioma-bearing model. Nude mice were anesthetized through administration of 10% chloral hydrate and the head was immobilized on a stoelting . Approximately 2.5 × 10Cypate = 0.1 mg/mL) were injected into normal mice and glioma-bearing mice through the tail vein. Bioluminescence imaging was performed at fixed times  using a small animals in vivo 3D bioluminescence imaging system .The nude mice were then sacrificed, and brains, liver, heart, spleen, lung, and kidney were collected for quantitative biodistribution analysis and ex vivo bioluminescence imaging [Orthotopic glioma-bearing model was established by injecting RG2 cells into the brain striatum as described above. Cypate, Cypate@LIP, Cypate@BLIP, Tf-Cypate@LIP and Tf-Cypate@BLIP (CP-gp.Orthotopic glioma-bearing model nude mice were randomly assigned into seven groups (6 mice/group) as follows: (1) control ; (2) CTX solution; (3) ELE solution (25 mg/kg ELE); (4) ELE/CTX@LIP; (5) ELE/CTX@BLIP; (6) Tf-ELE/CTX@LIP; (7) Tf-ELE/CTX@BLIP, to explore the anti-tumor effect in vivo. Treatments were administered by intravenous injection through the tail at day 1, 3, 5, 7, 9 and 11. Group 2, 4, 5, 6, 7 was administered with 2.5 mg/kg (CTX) on the first time and 0.625 mg/kg for the subsequent 5 injections. Bioluminescence imaging was performed at day 1, 5, 10, and 15 to explore tumor growth. Body weight and survival time were recorded every 3 days. Nude mice were euthanized 2 h post-treatment and their brains were collected for H&E staining, TUNEL immunofluorescence staining and detection of glioma Glioma-bearing nude mice were assigned into seven groups and were administered with (1) control ; (2) CTX solution; (3) ELE solution; (4) ELE/CTX@LIP; (5) ELE/CTX@BLIP; (6) Tf-ELE/CTX@LIP; (7) Tf-ELE/CTX@BLIP, 6 times and every other day. Whole blood samples were collected from retro-orbital sinus of glioma-bearing nude mice 2 h post-treatment. A portion of the complete blood samples was used for complete blood count analysis. The supernatant (serum) of the portion of blood obtained after centrifugation  was used for determination of biochemical indexes of liver and kidney, including total bilirubin, blood urea nitrogen, uric acid, alanine transaminase, creatinine and aspartate transaminase level. Liver, heart, spleen, lung and kidney sections were stained with H&E to evaluate effects of free ELE, CTX solution and liposomes toxicity .t test for comparison between two groups and ANOVA for comparison among multiple groups. Statistical difference was defined as significant for *p < 0.05 and highly significant for **p < 0.01.GraphPad Prism 8.0.2.263 software  was used for statistical analysis. Data were expressed as mean ± SD. Experimental data were analyzed using two-tailed Student Additional file 1: Table S1. Encapsulation efficiency stability of the drug in 4 liposomes at 3 months (n = 3). Fig. S1. Diameter and ζ-potential of Tf-ELE/CTX@BLIP, Tf-ELE/CTX@LIP, ELE/CTX@BLIP and ELE/CTX@LIP. Fig. S2. 7-days stability of TF-ELE/CTX@BLIP diameter in different medium. Fig. S3. Flow cytometry analysis of RG2 glioma cells after incubation with Tf-ELE/CTX@BLIP, Tf-ELE/CTX@LIP, ELE/CTX@BLIP and ELE/CTX@LIP for 2 h. Rho B = 20 μg/mL. Fig. S4. CLSM images of RG2, U251 and C6 glioma cells treated with Tf-ELE/CTX@BLIP for 2 h. Scale bar = 50 μm. Fig. S5. Flow cytometry analysis of RAW264.7 cells treated with Tf-ELE/CTX@BLIP, Tf-ELE/CTX@LIP, ELE/CTX@BLIP and ELE/CTX@LIP for 2 h. Rho B = 20 μg/mL. Fig. S6. WB analysis of P-gp in bEnd.3 cells. Relative protein expression was calculated. Cells preconditioned with (1) control; (2) verapamil; (3) ELE/CTX@LIP; (4) ELE/CTX@BLIP; (5) Tf-ELE/CTX@LIP; (6) Tf-ELE/CTX@BLIP. . Fig. S7. Corresponding quantitative fluorescent analysis of brain, liver, heart, spleen, lung and kidney at 48 h post-injection in glioma-beard mice. *p < 0.05. Fig. S8. In vivo fluorescence imaging of Tf-Cypate@BLIP, Tf-Cypate@LIP, Cypate@BLIP and Cypate@LIP in normal mice. Cypate = 0.5 mg/kg. Fig. S9. Averaged fluorescent intensity of saline, free CTX, free ELE, ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP in nude mice bearing orthotopic glioma brain within 15 days of treatments. Fig. S10. H&E staining of brain sections of orthotopic glioma-bearing mice in different formulation groups. Fig. S11. Biochemical parameter analysis after treated with saline, free CTX, free ELE, ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP. (A) BLI-T: total bilirubin, (B) BUN: blood urea nitrogen, (C) URIC: uric acid, (D) ALT: alanine transaminase, (E) CRE: creatinine, (F) AST: aspartate transaminase.


TP53 aberrations exert a more detrimental prognostic impact, compared to biallelic alterations.” This is incorrect. It should read: “Monoallelic TP53 alterations exert a less detrimental prognostic impact, compared to biallelic alterations.”There was an error in the original publication. Page 3. “Monoallelic TP53 mutations [2].” Reference [2] was erroneously cited. The correct reference here should be reference [1]. This sentence should read: “In fact, among our recently reported cohort of 20 spontaneously regressing CLL cases, three harbored TP53 mutations [1].”There was an error in the original publication. Page 13. “In fact, among our recently reported cohort of 20 spontaneously regressing CLL cases, three harbored There was an error in the original publication. Page 14. “in combination with existing immunomodulatory agents such as the PD-1/PD-L1 inhibitors lenalidomide and ibrutinib” This sentence should read in “in combination with existing immunomodulatory agents such as PD-1/PD-L1 inhibitors, lenalidomide and ibrutinib.”In the original publication, there was a mistake in Table 1: “Döhner” was misspelt as “Doner”. The corrected The authors wish to make the following corrections to their paper :There waThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated.


In


The authors regret that the image of OS-RC-2 invasion group was wrongly attached due to their carelessness in assembling figures Fig.D 1. The The correction made in this erratum does not affect the original conclusions. The authors apologize for any inconvenience or misunderstanding that this error may have caused.


Bioinformatics (2020) doi: 10.1093/bioinformatics/btaa758“The title of this paper was originally, erroneously displayed as “Decombinator V4: an improved AIRR compliant-software package for T-cell receptor sequence annotation?”. This should have appeared as “Decombinator V4: an improved AIRR-C compliant software package for T-cell receptor sequence annotation. This has now been corrected online”.


We acknowledge the points raised by Hodac and Wittekind  and woulWe thank the authors for the opportunity to discuss our findings in more detail. A more in-depth comparison between our estimates and the one provided by  is limit


After publication of the original article, the authors noted that thefollowing error had occurred:Molecular profilingidentified a subset of SOX2-regulated miRNAs in glioma stemcells”. In the passage that reads:The wrong publication was referenced in the analysis performed to identifySox2-regulated miRNAs in the section entitled “To provide robustness to this miRNA profile, we cross-referenced ourmiRNA array results to a set of miRNAs identified by Lopez-Bertoni andcolleagues to be regulated by exogenous expression of SOX2 in GSCs. Lopez et. al. identified 21 down-regulated and 56up-regulated miRNAs in GSCs expressing exogenous SOX2.


The beginning of the Supplemental text should have appeared as below. The error only exists in PDFs downloaded before March 9, 2021.f(t) that describes the kinetics of a Ca2+ transient:Let’s have a function


The authors have retracted this article because following verification, the results of the statistical analysis of the data presented in Fig. 4D and Fig. 6D were identified to be incorrect; specifically, the TUNEL assay results indicated that microRNA-144 could not reverse the effects of HCG11 on apoptosis, which affected the overall conclusions of the study.All authors agree to this retraction.


None of the authors should have been attributed equal contribution to this work.


The authors regret that the affiliations for Professor F. Puglisi are incorrect. They should be:CRO Aviano National Cancer Institute IRCCS, Aviano, Italy and Department of Medicine (DAME), University of Udine, Udine, ItalyThe authors would like to apologise for any inconvenience caused.


The Competing Interests statement published incorrectly. The publisher apologizes for the error. The correct statement is as follows: The authors have read the journal’s policy and the authors of this manuscript have the following competing interests: JT discloses a consulting relationship with Genetika, and JKW discloses paid employment with the Center for Translational Bioethics and Health Care Policy at Geisinger during the conduct of this study but no active competing interests at the time of publication. The authors have declared that no other competing interests exist and that the authors have no financial interests  related to this study to declare. This does not alter our adherence to PLOS ONE policies on sharing data and materials.


We apologize for the errors and for any inconvenience thatthis may have caused the readers of


There are errors in the Funding statement. The correct Funding statement is as follows: The authors received no specific funding for this work.


After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors attention by a concerned reader that certain of the western blotting data shown in Figs. 4C, 5B and 6D were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere prior to its submission to


The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates.


Investigation of a pertussis outbreak and comparison of two acellular booster pertussis vaccines in a junior school in South East England, 2019’ by Tessier et al., published on 25 March 2021, Repevax was mistakenly stated as having ten times more pertussis toxid than Infanrix. The text was corrected on 13 January 2022 on request of the authors. In the article ‘


This Retraction follows an Expression of Concern relating to this article previously published by Portland Press.Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to a duplicated image in Figure 4D.This article is being retracted from The authors were contacted regarding the concerns raised and provided a replacement images for Figures 2D, 3F and 4D, however given that the replacement images for Figure 2D also contained a new duplicated image, the Editorial Board stands by the decision to retract. The authors were contacted in regards to the retraction but did not respond.


There is an error in


While Europe’s response to the pandemic has been laudable, there remains more to be done in order to prevent economic scarring and ensure a robust recovery.


PLOS Genetics Editors that results from experiments reported in Fig 5M and 5N were not reproducible in follow-up experiments, raising questions about the validity of the main conclusions.Following publication of this article , the autIn Fig 5M and 5N of this article , the autGiven the results noted above, the authors consider the conclusions, and in particular the results reported in Fig 5M and 5N, invalid. Therefore, the authors are retracting this publication.PLOS Genetics for the inconvenience.The authors apologize to the readers and editors of All authors agreed with the retraction.


In the article titled “Chaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung” , the aut“LAMP2A HSC70 ”to“LAMP2A HSC70 ”


The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of


In


Erratum for Volume 12, no. 3, e00560-21, 2021, In


Fig. S3D and E).” Following the publication of the above article, the authors have realized that, on p. 8, some of the supplementary data were cited incorrectly in the main text. In the right-hand column, second paragraph, the sentence beginning on line 5 should have read as follows (changed text is highlighted in bold): “Meanwhile, the expression of miR-513b-5p in tumor tissues was decreased and the expression of PRPF39 was increased in tumor tissues with knockout of circ-G004213 (The authors regret their oversight in failing to correct the inaccurate citation of the data in the paper, are grateful to the Editor for allowing them the opportunity to publish this Corrigendum, and apologize to the readership for any inconvenience caused.


The authors would like to make an addendum to their published paper .The animal experimentation methodology was reviewed and approved by the Animal Welfare Committee of Eötvös Loránd University (reference number TTK/6859/1 (2021), certificate number ELTE-AWC-011/2021), and additionally by a higher governmental office .Furthermore, the authors retrospectively obtained the approval for the human ethical aspects of the informed consent form and the participant prospectus for the dog owners who participated with their dogs in the experiments .Animals.The authors submitted all the above mentioned documents, along with a copy of the owner consent form and participant prospectus, to In the originally published version of this article, ethical information was omitted, so the authors wish to add the following information regarding the ethical approval process of the experimental protocols:The change does not affect the scientific results.The rest of the manuscript does not need to be changed.


Bioinformatics (2021), Volume 37(Suppl1), i468–i476, doi:10.1093/bioinformatics/btab331Precision and Recall  were erroneously provided as: In the original published version, the formulae for The correct formulae that were consistently used throughout the experiments are as follows:The error is thus only in mis-typing the formulae themselves; not in the actual calculations of the precision and the recall used throughout the paper.As such, the other parts of the manuscript – specifically the experimental results reported, all stand as they appear in the original publication, and are not impacted by this correction.


In our paper


In fact, in the original publication, the spectra are plotted as functions of angular frequency.The authors wish to make the following corrections to this paper: . In SectBecause of the above mentioned


Soc. Rev., 2021, 50, 7820–7880, DOI: 10.1039/D0CS00729C.Correction for ‘The multifaceted nature of antimicrobial peptides: current synthetic chemistry approaches and future directions’ by Bee Ha Gan  The authors regret that the following funding information was omitted from the original article: “We gratefully acknowledge the financial support from the Swiss National Science Foundation (P2BEP2-191784) to B. H. G.”The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


The COVID-19 crisis has revealed the deep technological and production dependencies of the EU on third countries in sectors deemed as particularly strategic and has thus fuelled the debate on (the lack of) European technological sovereignty in critical fields. This article argues that in the light of a renewed interest in relaunching a European industrial policy, technological sovereignty considerations must be fully incorporated into policy objectives and instruments.


After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors’ attention by a concerned reader that the western blotting assay data shown in Fig. 2B were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to


Humanities and Social Sciences Communications 10.1057/s41599-021-00805-x, published online 27 May 2021.Correction to: The affiliation of one of the authors was wrongly stated as:Kumaran Rajandran, School of Humanities, Universiti Sains, Sains, MalaysiaThis has now been corrected to:Kumaran Rajandran, School of Humanities, Universiti Sains Malaysia, George Town, MalaysiaThis has been corrected in all versions of the paper.


Correction of conflict of interest statementOriginal statement: The authors declare that they have no conflict of interest.Corrected version:Conflict of interestThe authors, except dr. Philippe Lambin, declare that they have no conflict of interest.Dr. Lambin reports, within and outside the submitted work, grants/sponsored research agreements from Varian medical, Oncoradiomics, ptTheragnostic, Health Innovation Ventures and DualTpharma. He received an advisor/presenter fee and/or reimbursement of travel costs/external grant writing fee and/or in kind manpower contribution from Oncoradiomics, BHV, Merck and Convert pharmaceuticals. Dr Lambin has shares in the company Oncoradiomics SA and Convert pharmaceuticals SA and is co-inventor of two issued patents with royalties on radiomics  licensed to Oncoradiomics and one issue patent on mtDNA (PCT/EP2014/059089) licensed to ptTheragnostic/DNAmito, three non-patentable invention (softwares) licensed to ptTheragnostic/DNAmito, Oncoradiomics and Health Innovation Ventures.


The following statement should be added to the Acknowledgments section of this paper: “CRediT roles for this study are as follows: Mohammed Mufrrih: Investigation; Biyao Chen: Formal analysis, Investigation; Shiu-Wan Chan: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing - original draft, Writing - review & editing.”Volume 6, no. 3, e00361-21, 2021,


The journal retracts the article, Effects of a Single Dose of Ivermectin on Viral and Clinical Outcomes in Asymptomatic SARS-CoV-2 Infected Subjects: A Pilot Clinical Trial in Lebanon , cited aFollowing publication, the authors contacted the editorial office regarding an error between files used for the statistical analysis.Adhering to our complaints procedure, an investigation was conducted that confirmed the error reported by the authors.This retraction was approved by the Editor in Chief of the journal.The authors agreed to this retraction.


The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive any reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors’ attention by a concerned reader that the Transwell cell migration assay data shown in Fig. 2C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to


The authors wish to make the following corrections to this paper :Change in Author Names (Add a new one)In the original version of our article , the stuThe corrected author list, affiliation list, authors contribution, and acknowledgements are provided below:MartínezGuillermo1MerineroManuel1Pérez-ArandaMaría1Pérez-SorianoEva María2OrtizTamara3VillamorEduardo4BeginesBelén1*AlcudiaAna1*1Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Seville. C/Profesor García González, 2, 41012 Seville, Spain; mtnezmun@gmail.com (G.M.); lolo191995@gmail.com (M.M.); mariapar89@gmail.com (M.P.-A.)2Department of Materials Science and Engineering and Transport, Escuela Politécnica Superior, University of Seville, 41011 Seville, Spain; evamps@us.es3Department of Normal and Pathological Cytology and Histology, Faculty of Medicine, University of Seville, 41009 Seville, Spain; tortiz@us.es4Faculty of Pharmacy, University of Seville. C/Profesor García González, 2, 41012 Seville, Spain; eduardovillamors@gmail.com*Correspondence: bbegines@us.es (B.B.); aalcudia@us.es (A.A.)Authors Contributions:Conceptualization and methodology, B.B. and A.A.; investigation, G.M., M.M., M.P.-A., and E.V.; writing—original draft preparation, G.M., M.M., M.P.-A., E.M.P.-S., T.O., and E.V.; writing—review and editing, T.O. and E.M.P.-S.; supervision, B.B., A.A.; funding acquisition, A.A. All authors have read and agreed to the published version of the manuscript.Acknowledgments: University of Seville Library for providing access to scientific and technical information resources. Some figures have been designed using resources from Freepik.com.The authors would like to apologize for any inconvenience caused to the readers by these changes.


Furthermore, the flow cytometric plots shown in Fig. 2B in the above paper appeared to be remarkably similar to data presented in a paper published in Oncology Reports has determined that the above paper should be retracted from the Journal on account of a lack of confidence concerning the originality and the authenticity of the data. The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of


The authors apologize for the original versions of our paper unfortunately contained some incorrect representative images. We used the wrong representative images during figure assembly. The IHC images of 7dCon-Runx2, 10dCon-CD146/COL1A1 and 10dT-Del-Runx2 in Figure The authors confirm that the corrections made in this erratum do not affect the original conclusions. The authors apologize for any consequences that these errors may have caused.


The authors regret that the scale bars for the SEM image in Fig. 3a and c were mislabelled. The correct scale bar should be 100 μm, and the corresponding SEM images are shown below.Fig. 3a SEM surface morphology for single layer DLC film.Fig. 3c SEM surface morphology for multilayer DLC film.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


We thank Ravnskov  for his


There is an error in There is also an error in In Tables


In the ITS2 fragment sequence analysis subsection of the Results, there is an error in the fifth sentence of the first paragraph. The correct sentence is: For example, a sample from western Sumba (SM1-108) possessed a G>T transversion at nt 538 but lacked a base transition at nt 479 .The images for Figs


VOLUME 285 (2010) PAGES 26532–26544C panel 3is duplicated in Fig. 10A, b iii. Fig.10A, a iii is duplicated as Fig. 1 inMicrobiology (2009), 155: 780–790.Fig. 5C panel 6 is duplicated asFig. 1A, b ii right, Fig. 10A, a iii isduplicated as Fig. 1A, a ii right, andFig. 10A, c is duplicated in Fig. 1A, din Plant Signaling & Behavior (2011) 6(5): 723–725,respectively representing different experimental conditions. Plant Signaling& Behavior as well as Microbiology havereplaced and corrected the figures which were overlapping with theJBC figures as mentioned above. Both PlantSignaling & Behavior and Microbiology havepublished a corrigendum related to the respective figures.This article has been withdrawn by the authors except Ajay Kumar Saxenaand Deepak Kumar Deep who could not be contacted. Fig. 5


The authors regret that incorrect versions of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


BJPsych Open (2022). Cambridge University Press 8(1), E14. DOI: Following publication in December 2021, discrepancies between Table 1 and the Abstract, Results and Discussion sections were discovered and the authors notified. Upon detailed investigation, further statistical and methodological problems were found and the Editors concluded that a corrigendum would not be sufficient to resolve these issues.The authors of the article agree with the decision.


Retraction Note to: BMC Pediatr 21, 299 (2021)https://doi.org/10.1186/s12887-021-02775-0The Editor has retracted this article because of concerns with the data presented and ethics approval for this study. After publication, the authors became aware of fundamental errors in the data presented in Tables 2 and 3 that undermined the conclusions drawn in this study and contacted the journal to request a retraction. Additional concerns have been raised about the Ethics Approvals for the study since the protocol was updated, but the authors were unable to provide evidence that these changes were approved by all relevant Institutional Review Boards.Authors Ting Yang, Xi Lai, Li Chen, Jie Chen, Ming Xue and Tingyu Li agree to this retraction. Authors Jing Wen, Jiang Zhu, Min Guo and Ting Tang have not responded to any correspondence from the editor or publisher about this retraction.


After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors attention by a concerned reader that certain of the western blotting data shown in Figs. 5D and 6 bore unexpected similarities to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to


Sci., 2021, 12, 13101–13119, DOI: 10.1039/D1SC04181A.Correction for ‘HCOOH disproportionation to MeOH promoted by molybdenum PNP complexes’ by Elisabetta Alberico  The authors regret that in Please note that complex 8 is also shown in Scheme 4 in the proposed mechanism for HCOOH decarbonylation (green part), and in i)-hydride species {Mo(H)(CO)2(CH3CN)[CH3N(CH2CH2P(CH(CH3)2)2)2]}. The correct formula, in agreement with the X-ray structure, is as follows and is shown above in 2(CH3CN)[CH3N(CH2CH2P(CH(CH3)2)2)2]}.Furthermore, a mistake was made in the caption of Fig. 6, showing the solid-state structure of complex 9: the latter has been incorrectly described as a Mo(The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


Scientific Reports 10.1038/s41598-020-68117-9, published online 07 July 2020Correction to: The original version of this Article contained an error in the Acknowledgments section.“This paper is supported by the SILICOFCM project that has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 777204. This research was also funded by Ministry of Education and Science of Serbia, grants OI 174028, III 41007, III 45019 and PROMIS, Science Fund of the Republic of Serbia. The authors acknowledge support from the City of Kragujevac, Serbia.”now reads:“This paper is supported by the SILICOFCM project that has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 777204. This research was also funded by Ministry of Education and Science of Serbia, grants OI 174028, III 41007, III 45019. The authors acknowledge support from the City of Kragujevac, Serbia.”The original Article has been corrected.


The authors also apologize for any inconvenience caused, and agree to address any additional questions regarding their results. All raw data are available from the authors upon request.The corrected versions of


Cardiovasc Res., cvab077, https://doi.org/10.1093/cvr/cvab077The authors have requested that Ralph Knöll be removed from the acknowledgments section of the paper and be added as a co-author.This change does not affect the overall scientific message of the paper.


With the help of Wen-Jing Li, the authors realized there was a mistake of surface temperature in the paper above. The surface temperature in the paper refers to the temperature recorded in images which was detected by the temperature receptors of the field infrared camera, instead of the real surface temperature. As there was no shelter to the field infrared camera in alpine meadow grasslands, the temperature of the camera increased rapidly under the sunshine. Thus the conclusion of the preferable temperature for pikas may be around 31~35°C was not right, neither the temperature in Figure 6. As there was no equipment to measure the surface temperature in the observation, it is hard to restore the original surface temperature. The data in Figure 6 can be used to compare the behavior characteristics of plateau pikas at different relative temperature.The authors would like to declare that the temperature in the paper refers to the temperature recorded in images which was detected by the temperature receptors of the field infrared camera, instead of the real surface temperature. The historic high air temperature in Dari County was 23.2°C . The temperature of the camera could increase rapidly under the sunshine, so the temperature in the paper can only be taken as a reference of the relative temperature.The authors would like to give an extra special thanks to Wen-Jing Li, who provides the professional advice and help.  Thanks to the letter by The authors would like to declare that the temperature in the paper refers to the temperature recorded in images detected by the field infrared camera’s temperature receptors, and does not reflect the actual surface temperature. The historic high air temperature in Dari County was 23.2°C , so the The authors would like to acknowledge Dr. Wen-Jing Li for pointing out this discrepancy in surface temperatures.


Addendum to:Cancer Gene Therapy10.1038/cgt.2016.51After careful review and discussions with the authors, the Editor-in-Chiefis issuing an editorial expression of concern to alert readers that the cell lines usedin this study  may have


Staphylococcus aureus by silver ions’ by Xiangwen Liao et al., RSC Adv., 2020, 10, 33221–33226. DOI: 10.1039/D0RA06357F.Retraction of ‘Functional disruption of staphylococcal accessory regulator A from  RSC Advances article as there is an error in the data and the conclusions of the paper are not supported.We, the named authors, hereby wholly retract this +via its conserved cysteine residues.Fig. 3B does not show the titration data of SarA, it is the titration data of a different protein, and therefore we cannot unequivocally conclude that SarA binds AgThe corresponding authors regret this oversight and apologise for any inconvenience to readers.Signed: Xiangwen Liao, Guijuan Jiang, Jing Wang and Jintao Wangth February 2021Date: 17RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,


After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors attention by a concerned reader that certain of the western blotting data shown in Figs. 3A and 4A, and tumor images in Fig. 5A, bore unexpected similarities to data appearing in different form in other articles by different authors. Owing to the fact that some of the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to


Following publication of the original article , the autThe authors alsofound that the cells in the left three columns  were inconsistent with those in the right three columns. In order to facilitate the readers’ understanding of that part of the content and avoid any possible confusion, we hereby provide the cells consistent with the right three columns as a supplement. The supplementary pictures are shown below in Fig. 3 (the last row). The original full field view of the last row of Fig. 3 is also provided in supplementary information Fig S2.In summary, we provide a correction of Figure 2f and a supplementary image for the last row of Fig. 3 as follows:1. The correction of Fig. Supplementary information Fig S1:2. The supplementary image for Fig. 3 (the last row):Supplementary information Fig S2:The authors apologize for these errors and any inconvenience to the reader.


The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive any reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the Transwell cell migration assay data shown in Fig. 5A were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to


The authors wish to make the following corrections to the paper : During 1Thi Tuong Vy Phan 1 phanttuongvy4@duytan.edu.vnCenter for Advanced Chemistry, Institute of Research and Development, Duy Tan University, 03 Quang Trung, Hai Chau, Danang 550000, Vietnam; We apologize for this unintentional mistake, which, however, does not affect the results of this manuscript and the conclusions drawn from them.


This Retraction follows an Expression of Concern relating to this article previously published by Portland Press.Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to unusual repeated background features in the Western blots.This article is being retracted from The authors have been contacted in regard to the retraction and were asked to provide the raw images for these Western blots. However as the images provided during the investigation differed from those in the published paper and appear to show signs of editing, the Editorial Board stands by the decision to retract. The authors were asked to agree to the retraction but did not respond to the Editorial Office.


VOLUME 284 (2009) PAGES 16183–16190B and 5C, a portion ofthe actin immunoblots were reused in the SMMC7721 panels. InFig. 6B, si-p53 panel, the p53 immunoblot bands for ICNand parental lanes are duplicated. Also in Fig. 6B, si-p53panel, the DR5 immunoblot bands for mock and parental lanes are duplicated. InFig. S1, the Notch 2 and Notch 3 panels are duplicated. The authors state that theydisagree with the Journal’s findings. This study was conducted nearly 15 years ago.The age of the work and the lack of availability of data storage makes it difficultfor the authors to retrieve the requested raw data. The authors’ offer to replacethe images in question with those from other experiments under the same conditionswas declined by the Journal. The authors state that the above issues do not affectthe interpretation of the data nor conclusions of this work. The authors state thatthe conclusions of this article have been confirmed by other independent studies.The authors have indicated that they plan to resubmit their findings elsewhere forpublication.This article has been withdrawn by the authors. The Journal statesthat in Figs. 5


The authors regret that the original version of our paper


The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors’ attention by a concerned reader that the scratch-wound assay data shown in Fig. 2C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to


The authors would like to make corrections to a recently published paper . The reaOriginal Figure 5:We would like it to be corrected as shown below.1.New Figure 5:2.The result of Section 3.1. Clinicopathological Characteristics and Progression of Breast Cancer.A total of 264 LN+ patients, with a median age of 56 years.3.The result of Section 3.2. A Significant Correlation Among RNF8, SNAI1, and CDH1 mRNA Expression in Patients with Breast Cancer.SNAI1 showed a significant positive correlation .4.J. Clin. Investig.2009, 119, 1420–1428. http://doi.org/10.1172/jci39104.The right reference No. 6 is: Kalluri, R.; Weinberg, R.A. The basics of epithelial-mesenchymal transition. JPM for this error. The published version will be updated on the article webpage, with a reference to this correction notice.These changes do not change the results or conclusions of our paper. The authors would like to apologize to readers of


Cell Death & Disease 10.1038/s41419-019-1748-1, published online 1 July 2019Correction to: The authors would like to correct Figs. The revised Fig. The revised Fig.


In the following article,2H2]‐glucose  and [U‐13C]‐palmitate  were started using a Gemini PC2 Pump .After blood and air sampling, infusions of [6.6‐The authors apologise for the errors.


The Journal and Authors retract the 8 February 2021 article cited above for the following reasons provided by the Authors:Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers’ policies.This retraction was approved by the Chief Editors of Frontiers in Oncology and the Chief Executive Editor of Frontiers. The authors agree to this retraction.


The authors have requested that the following changes be made to their paper .The original authors wish to add Dr. Amanda M. Fretts as a coauthor to this paper, as she was mistakenly left off in the original published version. Contributions by Dr. Fretts included study conceptualization, supervision, and revision/editing of the manuscript. She approved the final manuscript for publication during August 2020. Unfortunately, it was not recognized by the authors until after publication that Dr. Fretts had been mistakenly left off of the author list.We would like to apologize for any inconvenience caused to the authors and readers by this mistake. The published version will be updated on the article webpage, with reference to this notice.


We regret the unprofessional behavior of the authors involved.li06yh@126.com>Correspondence: Yinghao Li: <


Proc. R. Soc. B288, 20210839. (Published online 28 July 2021) (doi:10.1098/rspb.2021.0839)Proc. R. Soc. B 288, 20210839. http://doi.org/10.1098/rspb.2021.0839In the paper Roi Harel, J. Carter Loftus and Margaret C. Crofoot 2021. Locomotor compromises maintain group cohesion in baboon troops on the move. The required change is to change the first institution for all of the authors from Department of Ecology, Evolution and Behavior, The Life Sciences Institute, The Hebrew University of Jerusalem, Givat Ram, Jerusalem 9190401, Israel to Department for the Ecology of Animal Societies, Max Planck Institute of Animal Behavior, Bücklestraβe 5, Konstanz 78467, Germany.


In paper “VISTO: An Open-Source Device to Measure Exposure Time in Psychological Experiments”, a device that measures the onset of experimental visual stimuli is described. This device acquires luminance information through a light sensor BPW42, and then records luminance waveforms or onset times. Throughout the paper however, sensor BPW42 was erroneously described as a photodiode, while it is a phototransistor. Moreover, the wiring scheme in In the revised The authors would like to apologize for any inconvenience caused.


The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive any reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors’ attention by a concerned reader that certain of the Transwell cell migration data shown in Fig. 4C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to


The Journal and Authors retract the 9 September 2020 article cited above for the following reasons provided by the Authors:Following publication, concerns were raised regarding image manipulation. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers’ policies.This retraction was approved by the Chief Editors of Frontiers in Oncology and Chief Executive Editor. The authors agree to this retraction.


Cell DiscoveryCorrection to: 10.1038/s41421-021-00281-2, published online 13 July 20211, we missed labeling the co-first authors. The first two authors, Jiayan Zhang and Hui Wang, who have contributed to this work equally, should have been designated with a footnote of “These authors contributed equally: Jiayan Zhang, Hui Wang”. This correction does not affect the description of the results or the conclusion of this work.In the original publication of this Correspondence


Furthermore, text for an Acknowledgments section for this paper has been added as follows:Acknowledgmentswww.pulsenotes.com).Note that the figure used in this review was reproduced with kind permission of The Pulsenotes Team (Oncology Letters regrets that this review was published without a proper acknowledgement being made to The Pulsenotes Team as the source of the figure, and the Journal is grateful to them for raising this matter with us as a concern. Furthermore, we apologize to The Pulsenotes Team for the inconvenience caused.These corrections have also been added to the published version of the paper. Note that the authors were also consulted, but the Editorial Office did not receive a timely response from them. The Editor of


The authors also apologize to the readership for any inconvenience these errors may have caused.Consequently, the corrected versions of


In our paper


In particular, the authors became aware of these errors when they prepared a webinar presentation in which they presented their validation work. The original Table 3 reported values for the tests performed by operator # 1, for dilutions G and H, different from the original raw data. Furthermore, by reanalyzing all the data in this table, we noticed that all the standard deviation measurements were calculated incorrectly. These have now been corrected online. The authors regret this error.


Oxidative Medicine and Cellular Longevity has retracted the article titled “Stearoyl-CoA Desaturase 1 Potentiates Hypoxic plus Nutrient-Deprived Pancreatic Cancer Cell Ferroptosis Resistance” [istance” . SpecifiThe authors do not agree to the retraction.


Following publication of the original article , the autIncorrect2 Translational Oncology, National Center for Tumor Diseases, German Cancer Research Center, Heidelberg, GermanyBenedikt Brors affiliations—1,2,5Correct2 Division of Translational Medical Oncology, National Center for Tumor Diseases, German Cancer Research Center, Heidelberg, GermanyBenedikt Brors affiliations—1,5


Dear Editor,In our publication  we stateThis statement is erroneous. Recently, it was pointed out to us that the Royal College of Obstetricians and Gynecologists of Canada Objectives of Training in the Specialty of Obstetrics and Gynecology were amended and include the following statement applicable after July 1, 2016:“The following procedures in List A are those that the fully trained resident in Obstetrics and Gynecology must be competent to perform independently: 5.2.2.41. Limited cystoscopy”We regret our error and apologise for any inconvenience.E-mail: gjacob2010@gmail.comG.P. Jacob, G.A. Vilos, F. Al Turki, G. Bhangav, B. Abu-Rafea, AG.. Vilos, A. Ternamian


The authors regret that:The EPSRC grant number currently stated in Funding Source section is `EP/K030957/1', which is incorrect. The correct funding source is `EP/N024818/1'.The authors would like to apologise for any inconvenience caused.


There is an error in


Sci., 2021, DOI: 10.1039/d0sc06186g.Correction for ‘Rhodium-catalysed selective C–C bond activation and borylation of cyclopropanes’ by Yandong Wang  The authors regret that there were a few errors in I is the kinetically favoured product” to the end of this paragraph should be corrected to “Finally, the catalytic species A is regenerated via dissociation of 12 or E13- from the Rh center. The enamide E13- is the kinetically favoured product, which supports the observation of 13 in Scheme 3A-3, where HBpin is not added.”On pages 6–7 of the original manuscript, the sentences from “The enamide These changes do not alter the scientific conclusions of the manuscript.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors attention by a concerned reader that certain of the flow cytometric and western blotting data shown in Fig. 3A and C respectively, and the tumor images shown in Fig. 7A, bore unexpected similarities to data appearing in different form in other articles by different authors. Owing to the fact that some of the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to


Sci., 2020, 11, 12731–12736, DOI: 10.1039/D0SC02351E.Correction for ‘On the electronic structure and hydrogen evolution reaction activity of platinum group metal-based high-entropy-alloy nanoparticles’ by Dongshuang Wu  The authors regret that there was an error in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


The dates for the cohort of people with 1 or more office-based addiction treatment encounters given as “January 1” and “December 21, 2018,” should have been “January 1, 2008,” and December 31, 2018.” This article has been corrected.1In the Original Investigation titled “Office-Based Addiction Treatment Retention and Mortality Among People Experiencing Homelessness,”


Sci., 2014, 5, 4474–4482, DOI: 10.1039/C4SC01605J.Correction for ‘Hydrogen-activation mechanism of [Fe] hydrogenase revealed by multi-scale modeling’ by Arndt Robert Finkelmann  In p and the oxypyridine O atom was given as 1.82 Å and the distance between Hp and the Fe atom was given as 1.7 Å. However, it should read 1.82 Å between Hp and Fe and 1.70 Å between Hp and the oxypyridine O atom. In p and Fe was shown to be 1.70 Å and the distance between Hd and Fe was given as 1.73 Å. However, it should read 1.73 Å between Hp and Fe and 1.70 Å between Hd and Fe. The correct versions of these figures are given below. The results and conclusions are not affected by these typographical errors.The authors regret that there were minor typographical errors in two figures. In The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


The Editorial Office has been unable to confirm such findings directly with authorities at the institution in accordance with standard practice. Given the nature of the concerns raised, the Editor-in-Chief wishes to alert the readers to interpret the results presented here with caution.Corresponding authors Insug Kang and Eui-Ju Yeo stated on behalf of all co-authors that they agree to this Expression of Concern.


Furthermore, flow cytometric data featured in Fig. 2D were strikingly similar to those in another previously published paper, and cell cyle data included in Fig. 3 had apparently previously published elsewhere.Owing to the fact that the contentious data in the above article had already appeared in different form in other articles prior to its submission to Molecular Medicine Reports, the Editor has decided that this paper should be retracted from the Journal. The authors also expressed their intention to retract the paper on the grounds that the corresponding author and several of the authors failed to confirm the approval of the final version of the manuscript. The Editor apologizes to the readership for any inconvenience caused.


The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates.


The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of


Sci., 2021, 12, 14432–14440, DOI: 10.1039/d1sc04138j.Correction for ‘Plasticizer and catalyst co-functionalized PEDOT:PSS enables stretchable electrochemical sensing of living cells’ by Jing Yan  The authors regret that there was an error in the equation of the calibration curve of PPL/PDMS in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


Following the publication of this article, the authors have reaized that Table II was printed containing certain numerical errors, although these were not significant enough to have affected the statistical results.Oncology Letters for allowing them the opportunity to publish this corrigendum, and all the authors agree to this corrigendum. Furthermore, the authors apologize to the readership for any inconvenience caused.The corrected version of Table II is shown on the next page, and the corrected data  are highlighted in bold. The authors are grateful to the Editor of


The affiliation of the corresponding author Sharon A. Tooze to the Institute of Cancer Research, Olso, Norway was incorrectly added. The authors would like to apologize for any inconvenience caused.


The authors regret that in the original article an incorrect email address was given for the corresponding author Sang-Wha Lee. The correct email address is shown here.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


Dauncey et al., Chem. Sci., 2019, 10, 7728–7733.Correction for ‘A dual photoredox-nickel strategy for remote functionalization  The authors regret that The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


CLINICS (Sao Paulo). 2021;76:e1512errhttps://doi.org/10.6061/clinics/2020/e1512, published in 2020.Erratum for: doi: Randomized trial of physiotherapy and hypertonic saline techniques for sputum induction in asthmatic children and adolescentsIn the article “Karina Pierantozzi Verganid” for: “Karina Pierantozzi Vergani”Replace and Page 6 – AUTHOR CONTRIBUTIONS“Verganid KP” replace for “Vergani KP”where it reads


The tenth and eleventh authors, Dante R. Culqui and Joan A. Caylà, should be noted as joint senior authors of this work. The publisher apologizes for the error.


Sci., 2020, 11, 6907–6914, DOI: 10.1039/D0SC02717K.Correction for ‘Effect of heterocycle content on metal binding isostere coordination’ by Benjamin L. Dick  The authors regret that a complete Conflicts of interest section was not shown in the original article. The correct Conflicts of interest section is shown below.The authors declare the following competing financial interest(s): S. M. C. is a co-founder of and has an equity interest in Cleave Therapeutics, Forge Therapeutics, and Blacksmith Medicines, companies that may potentially benefit from the research results. S. M. C. also serves on the Scientific Advisory Board for Blacksmith Medicines and serves on the Scientific Advisory Board and receives compensation from Forge Therapeutics. The terms of this arrangement have been reviewed and approved by the University of California, San Diego in accordance with its conflict of interest policies.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors’ attention by a concerned reader that certain of the western blot assay data shown in Figs. 1C and 6A were strikingly similar to data appearing in different form in another article written by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to


After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors’ attention by a concerned reader that the western blot assay data shown in Figs. 1B, 5A, 6A and C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to


Retraction to: BMC Complement Altern Med 17, 458 (2017)https://doi.org/10.1186/s12906-017-1958-yIn Fig. 2 it appears that ‘Control Positive’ and ‘Leaf’ show the same image and that ‘Bark’ and ‘Root’ show the same imageIn Fig. 5 it appears that ‘CH Leaves’ and ‘CH Bark’ show the same image, albeit rotatedIn Fig. 5 it appears that ‘CH Flowers’ and ‘EA Bark’ show the same image, albeit rotatedIn Fig. 5 it appears that ‘HE Bark’ and ‘EA Roots’ show the same image, albeit rotatedIn Fig. 5 it appears that ‘EA Flowers’ and ‘HE Roots’ shows the same imageThe Editor in Chief has retracted this article  because The authors provided additional data, but were not able to show original images for these figures. The Editor-in-Chief therefore no longer has confidence in the integrity of the data in this article.Both authors, P.V.V. Satish and K. Sunita have not explicitly stated whether they agree to this retraction notice.


VOLUME 293 (2018) PAGES 19025–19037D, the PLA images forXPA-WT, XPA-K63Q, and XPA-K67Q were duplicated. Also inFig. 3D, the DAPI merged images for XPA-WT and XPA-K63Qwere duplicated.This article has been withdrawn by the authors except StuartJarrett, who could not be reached. The withdrawing authors were unable to provideoriginal data corresponding to many of the micrographs presented in the articleaccording to Journal policy. In Fig. 3


After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors’ attention by a concerned reader that the western blotting data in Figs. 3 and 6 were strikingly similar to data appearing in different form in other articles by different authors at different research institutes. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere prior to its submission to


The authors regret to acknowledge financial support from Ministerio de Ciencia e Innovación (MCI), Agencia Estatal de Investigación (AEI) and Fondo Europeo de Desarrollo Regional (FEDER) through MOCCA Project (RTI2018-093941-B-C31).The authors would like to apologise for any inconvenience caused.


Following publication, concerns were raised regarding image manipulation. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' guidelines.This retraction was approved by the Chief Editors of Frontiers in Cellular and Development and the Editor-in-Chief of Frontiers. The authors [did] agree to this retraction.


There is an error in the affiliations for authors Miraine Dávila Felipe and Olivier Gascuel. Neither author should have a current address listed and both authors have two affiliations.Both authors are affiliated to #1: Unité Bioinformatique Evolutive, Département de Biologie Computationelle, Institut Pasteur, Paris, France.The correct second affiliation for Miraine Dávila Felipe is: Université de technologie de Compiègne, LMAC (Laboratory of Applied Mathematics of Compiègne), Compiègne, France.The correct second affiliation for Olivier Gascuel is: Institut de Systématique, Evolution, Biodiversité , Paris, France.


Ms. Jill Harris has requested that she should be removed from the list of contributing authors. After re-considering her contribution, we wish to remove her from the authorship of our paper  and add


There is an error in the Conclusion subsection of the Abstract. The correct sentence is: A low autonomic nervous system activity, i.e. low SDNN or Energy, and a predominance of the parasympathetic system, i.e. high HFnu or ANIm, due to the sympathetic depletion in COVID-19 patients are associated with a worse prognosis, higher mortality, and higher IL-6 levels.


The authors regret that the affiliations of three of the authors  were shown incorrectly in the original article. The corrected author list and affiliations are as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


The authors state that the images used in the original


Sci., 2023, https://doi.org/10.1039/D2SC05051J.Correction for ‘Bond breaking of furan–maleimide adducts  The authors regret that a typo in the corresponding author designation in the list of authors, appeared in the original manuscript. The corrected list of authors for this paper is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


Behavioral Ecology, Volume 30, Issue 2, March/April 2019, Pages 348–355, https://doi.org/10.1093/beheco/ary171This is an Expression of Concern regarding: Molly M Ashur, Danielle L Dixson, Multiple environmental cues impact habitat choice during nocturnal homing of specialized reef shrimp, The Editor-in-Chief has been alerted to concerns about the credibility of the data in the above paper.The journal is publishing this Expression of Concern to alert readers while we investigate to determine whether further action is required.


Unfortunately, the authors could not provide the original data, despite the paper being published so recently. The authors re-analysed their samples and supplied cropped replicate blots and analyses, stating that these results support the conclusions of the paper.The journal concluded that without the original data for the published figures, we have no option but to retract this paper. This course of action follows the advice set out by COPE (Committee on Publication Ethics), of which Biology Open is a member.The authors did not respond to say whether they agree with this retraction.


Communications Biology 10.1038/s42003-022-03193-3, published online 15 March 2022.Correction to: In this Q&A the affiliation details for Victor Garcia were incorrectly given as “Associate Professor at New York Medical College” but should have been “Assistant Professor at New York Medical College”.Both errors have now been corrected in the HTML and PDF versions of the Q&A.


Increases in life expectancy over the last 50 years has been matched by an increase in the burden of diseases (e.g. herpes zoster (HZ)) in adults ≥50 years of age (YOA). Without intervention, around 30% of individuals can expect to develop HZ in their lifetime, which would impact their daily activities and healthy ageing.We conducted a narrative review on published literature on the impact of developing HZ on healthy ageing and the ability of vaccination to prevent the burden of disease due to HZ. Specifically, we describe HZ impact on quality of life (QoL), and impact of the adjuvanted recombinant zoster vaccine (RZV) on reducing the burden of HZ in adults ≥50 YOA.In adults ≥50 YOA with HZ, 65.1% and 15.8% reported severe pain and worst imaginable pain, respectively. Pain persisted for up to 90 days  in 10-20% of HZ patients, and occasionally for years after initial symptoms. Pain due to HZ impacted all domains of QoL . Evidence suggested that RZV reduced HZ burden of illness and burden of interference on daily activities by > 90%. Reports also suggested that RZV retained vaccine efficacy of > 90% in all frailty subgroups, who typically respond poorly to other vaccinations. Long-term follow-up data reported vaccine efficacy against HZ of 84.1% , 8 years post-vaccination. Modelling studies demonstrated that vaccination resulted in reduced hospitalization and other healthcare visits related to HZ.Vaccination with RZV can protect older adults from HZ, thus maintaining QoL and promoting active and healthy ageing.• There is significant burden of disease due to HZ among adults ≥50 YOA due to ageing and immunosenescence.• Vaccination can reduce burden of disease among the elderly and frail individuals and maintain QoL.


Ind. Crop & Prod. A,1 which should have been cited in this RSC Advances paper.The authors wish to draw the readers’ attention to their closely related paper, in The authors regret the unattributed text, figure and data overlap between their article and ref. 1. Table 1, Fig. 2, Fig. 3 and Table 2 were re-used in part or in full from ref. 1 without being correctly attributed and without permission from the Publisher.The authors have now received the permission to reuse the images and the corrected captions are shown below:Ind. Crops Prod., 2015, 74, 417–424, with permission from Elsevier.Table 1 Effect of SW water extractives on the mechanical performance of gypsum. Reprinted in part from Dasong Dai and Mizi Fan, ‘Preparation of bio-composite from wood sawdust and gypsum’, Ind. Crops Prod., 2015, 74, 417–424, with permission from Elsevier.Fig. 2 ATR-FTIR spectra of WBE coating SW, raw SW and subtraction from the surface of WBE coating SW. Reprinted from Dasong Dai and Mizi Fan, ‘Preparation of bio-composite from wood sawdust and gypsum’, Ind. Crops Prod., 2015, 74, 417–424, with permission from Elsevier.Fig. 3 Matching result of subtraction from the surface of WBE coating sawdust with OMNIC software. Reprinted from Dasong Dai and Mizi Fan, ‘Preparation of bio-composite from wood sawdust and gypsum’, Ind. Crops Prod., 2015, 74, 417–424, with permission from Elsevier.Table 2 Effect of SW modification on the mechanical performance of gypsum/SW composite (with ultrasonic pretreatment). Reprinted in part from Dasong Dai and Mizi Fan, ‘Preparation of bio-composite from wood sawdust and gypsum’, The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


The journal retracts the 22 August 2019, article cited above.Following publication, concerns were raised regarding the substantial similarity of content with two of the authors’ previous publications. An investigation was conducted in accordance with Frontiers’ policies, whereby it was confirmed that the degree of reuse of the previously published content is inconsistent with our editorial requirements for originality. Following the Committee on Publication Ethics guidelines, this article, published most recently, is retracted. This retraction was approved by the Chief Editors of Frontiers in Pharmacology, and the Chief Executive Editor of Frontiers. The authors agree to this retraction.The authors concur with the retraction and sincerely regret any inconvenience this may have caused to the reviewers, editors, and readers of Frontiers in Pharmacology.


Journal of Healthcare Engineering has retracted the article titled “The Potential Mechanism of Exercise Combined with Natural Extracts to Prevent and Treat Postmenopausal Osteoporosis” [porosis”  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction.


One microscopic image of tissue sections of the mouse brain in Fig. S5 (Supplementary Files) was chosen incorrectly due to wrong data naming. We have performed the histological examination again to ensure scientific rigor in this work. The newly arranged Fig. S5 is as follows. Notably, the correction does not affect the main conclusion of our paper. We genuinely apologize to the Editor and the readership of the journal for any inconvenience it caused.


N-(6-(4-(pyrazine-2-carbonyl)piperazine/homopiperazine-1-yl)pyridin-3-yl)benzamide derivatives as anti-tubercular agents’ by Singireddi Srinivasarao et al., RSC Adv., 2020, 10, 12272–12288, DOI: 10.1039/D0RA01348J.Correction for ‘Seeking potent anti-tubercular agents: design and synthesis of substituted- The authors regret that the name of one of the authors (Linda De Vooght) was shown incorrectly in the original article. The corrected author list is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


A new MRI examination showed a persistent lack of enhancement and involvement of U-fibers (A 78-year-old man was admitted to the emergency department because of disorientation, gait imbalance, and dysarthria for 3 weeks. Brain ic edema . LaboratU-fibers . Based o


The authors regret that an incorrect figure caption was given for The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


The authors regret that the affiliations were incorrectly shown in the original manuscript. The corrected list of affiliations is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


The following information is missing from the Competing Interests statement:PLOS ONE policies on sharing data and materials.Dr. Harald Matthes is a member of the board of directors at Weleda AG, a company that until 2016 distributed Iscador, a mistletoe preparation. In addition, Dr. Harald Matthes is a member of the board of the Hufelandgesellschaft e. V. in Germany; President of the DAHN (German Academy for Homeopathy and Naturopathy); and medical director and managing director of Gemeinschaftskrankenhaus Havelhöhe, a hospital for anthroposophic medicine. Dr. Harald Matthes is also a recipient on an endowed professorship from Charité in Berlin on Integrative and Anthroposophical Medicine. These competing interests do not alter the authors’ adherence to


The authors regret a mistake in the author names of ref. 44. The correct reference is shown below as ref. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


Independently of the reader's enquiry, the authors contacted the Editorial Office to request that the paper be retracted on account of the fact that they were unable to reproduce the results presented in Fig. 2.Oncology Reports, and in line with the authors' own request, the Editor has decided that this paper should be retracted from the Journal. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere when it was submitted to


Sci., 2021, 14, 2335–2348; DOI: 10.1039/D0EE02984J.Correction for ‘Optimizing accuracy and efficacy in data-driven materials discovery for the solar production of hydrogen’ by Yihuang Xiong  The following funding source was missing from the Acknowledgments section:The National Science Foundation through the Research Experiences for Undergraduates and Research Experiences for Teachers in Nanoscale Physics and Materials at Pennsylvania State University under Grant No., DMR142062 and DMR2011839.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.


The text should read “The precursor glass (PG) compositions (mol%) is 17.5 KF-17.5 ZnFThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.